{"meta":{"query_hash":"f25a8327a313","filters":{"topic":"Tryptophan and brain disorders"},"cohort_total":1766,"direct_labels_cover":6,"predictions_cover":1766,"exported":1766,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/f25a8327a313","api":"https://metacan.xera.ac/api/v1/cohort?topic=Tryptophan+and+brain+disorders"},"results":[{"id":"W1199033123","doi":"10.3233/nib-2011-001","title":"Introduction: Advances in Neuroimmune Biology: A Comprehensive way to Look at Biology","year":2011,"lang":"en","type":"article","venue":"Advances in Neuroimmune Biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Neuroscience; Biology; Cognitive science; Computational biology; Psychology","score_opus":0.03129872374816376,"score_gpt":0.29805630614530565,"score_spread":0.26675758239714187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1199033123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9618354,0.024808202,0.00021953999,0.0018868602,0.0053349556,0.0009764725,0.00004948722,0.00024733334,0.004641751],"genre_scores_gemma":[0.9783256,0.01712052,0.00048759312,0.0033643774,0.00023679859,0.00016631144,0.00003387592,0.000056871493,0.00020804013],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9949097,0.0010099963,0.0009520625,0.0018372901,0.000097521726,0.0011934001],"domain_scores_gemma":[0.9977972,0.00072721095,0.00031279676,0.0009784343,0.00006165057,0.00012270211],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019729945,0.00056884636,0.0008705469,0.0007082395,0.00019584429,0.0000135088285,0.0011702476,0.00028617485,0.00042648238],"category_scores_gemma":[0.0009910292,0.0005225041,0.00013729613,0.0013400973,0.0013712213,0.0005596439,0.0007632827,0.0006504174,0.00041746316],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011764382,0.0004357544,0.037110936,0.000043123066,0.0000070952783,0.00008385387,0.0006727788,0.00017677946,0.8921863,0.025449112,0.00016487027,0.042492997],"study_design_scores_gemma":[0.0027963824,0.0024663196,0.08496296,0.000041103835,0.0000076287347,0.00019351592,0.00027401466,0.000048807076,0.114056684,0.019553697,0.7745492,0.0010496768],"about_ca_topic_score_codex":0.00009037504,"about_ca_topic_score_gemma":0.0003363945,"teacher_disagreement_score":0.7781296,"about_ca_system_score_codex":0.000100470235,"about_ca_system_score_gemma":0.000037291746,"threshold_uncertainty_score":0.99972266},"labels":[],"label_agreement":null},{"id":"W1410305370","doi":"10.3233/jad-2008-13401","title":"Chronic Inflammation and Amyloidogenesis in Alzheimer's Disease: The Emerging Role of Infection","year":2008,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Inflammation; Disease; Medicine; Immunology; Neuroscience; Biology; Pathology","score_opus":0.025196547182204015,"score_gpt":0.26127777340471864,"score_spread":0.23608122622251462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1410305370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9643772,0.034291524,0.000016128359,0.00090268196,0.0001333624,0.00018170895,0.000006464356,0.0000116235315,0.00007930513],"genre_scores_gemma":[0.99754184,0.0021260316,0.00001314006,0.000085238804,0.0002071385,0.0000069584985,8.6949615e-7,0.000015487623,0.0000032804942],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99862474,0.00017498492,0.00046264776,0.00016551212,0.00038378494,0.00018835205],"domain_scores_gemma":[0.9990271,0.000101902624,0.00039474136,0.00018208829,0.000064003696,0.00023021112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018252966,0.00013847764,0.00018277224,0.0002308805,0.00014499524,0.000022912765,0.00014949378,0.000030152842,0.000046877],"category_scores_gemma":[0.00023872257,0.000102934755,0.00014473686,0.00035199244,0.00020287535,0.0004588948,0.00005022218,0.00015087596,0.00000494233],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022016065,0.0010497579,0.42585942,0.00013485311,0.0006483869,0.0005896648,0.0037935402,0.01509428,0.31307423,0.002202106,0.000915423,0.23443675],"study_design_scores_gemma":[0.0010434212,0.000092592745,0.92563564,0.00007926154,0.0003559374,0.000039107847,0.00006838664,0.0016271743,0.06834913,0.0011522898,0.0013743028,0.00018277076],"about_ca_topic_score_codex":0.000028467164,"about_ca_topic_score_gemma":0.000012866058,"teacher_disagreement_score":0.4997762,"about_ca_system_score_codex":0.000022847616,"about_ca_system_score_gemma":0.00024174922,"threshold_uncertainty_score":0.41975576},"labels":[],"label_agreement":null},{"id":"W1448410398","doi":"10.1016/j.pnpbp.2015.08.016","title":"The role of oxidative and nitrosative stress in accelerated aging and major depressive disorder","year":2015,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":171,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Major depressive disorder; Coenzyme Q10; Oxidative stress; Medicine; Depression (economics); Internal medicine; Bioinformatics; Biology","score_opus":0.0468512627621319,"score_gpt":0.3684976531370654,"score_spread":0.3216463903749335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1448410398","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15935351,0.83839566,5.734796e-7,0.0002902607,0.0004257473,0.0012758729,0.00008891104,0.000029147928,0.000140306],"genre_scores_gemma":[0.07914368,0.92006016,0.000051974832,0.00028155374,0.000067244306,0.00035214928,0.000010349496,0.000026113428,0.0000068022596],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960395,0.0014613635,0.0007186765,0.0010942782,0.00014565099,0.0005405285],"domain_scores_gemma":[0.9976418,0.0014784693,0.0005081975,0.00018944702,0.00003748431,0.00014461369],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035150824,0.00053961464,0.0011282393,0.000244457,0.00021192523,0.00006398202,0.00047710017,0.00047124363,0.000012463507],"category_scores_gemma":[0.00022743229,0.0003200349,0.00008781542,0.00062686007,0.0019944203,0.00011241844,0.00038889918,0.0011338213,0.00000149229],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005076292,0.00045774793,0.19275832,0.0008209291,0.00004393046,0.000028174667,0.00017515439,3.254291e-7,0.000047790007,0.0009441593,0.00005402042,0.80416185],"study_design_scores_gemma":[0.03871562,0.0045607854,0.29600775,0.009678514,0.00085390883,0.00059614854,0.0036638957,0.0003310534,0.00051578955,0.07432734,0.56527907,0.005470134],"about_ca_topic_score_codex":0.0000055686155,"about_ca_topic_score_gemma":0.000031648782,"teacher_disagreement_score":0.7986917,"about_ca_system_score_codex":0.000014730334,"about_ca_system_score_gemma":0.000092176015,"threshold_uncertainty_score":0.9999252},"labels":[],"label_agreement":null},{"id":"W1483881410","doi":"10.1016/j.psychres.2015.06.009","title":"Examining the role of neuroinflammation in major depression","year":2015,"lang":"en","type":"review","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":193,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University; NOSM University; University of Toronto; Adler; START Clinic","funders":"","keywords":"Depression (economics); Proinflammatory cytokine; Neuroinflammation; Inflammation; Tumor necrosis factor alpha; Medicine; Cytokine; Immune system; Interleukin 6; Psychology; Immunology; Internal medicine","score_opus":0.2017685477458423,"score_gpt":0.4260081048920034,"score_spread":0.22423955714616112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1483881410","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022272433,0.98239666,9.0293497e-7,0.000088469154,0.0003187839,0.0010195815,0.000010891835,0.000024157756,0.01391331],"genre_scores_gemma":[0.0022063921,0.9971192,0.000042649892,0.000011604152,0.00018241558,0.00014244103,0.0000065685217,0.000048618487,0.00024013434],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9955556,0.0019126153,0.0005338498,0.0005386214,0.0010038276,0.00045549334],"domain_scores_gemma":[0.99803996,0.0009050677,0.0002075731,0.0007019949,0.00006247808,0.00008290085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020250948,0.00020456841,0.00053962367,0.0005421884,0.00013511207,0.0000639405,0.0011006714,0.00019262168,0.000050727216],"category_scores_gemma":[0.0010732252,0.00012885738,0.00012203083,0.0015781412,0.00021121932,0.00010399781,0.00032335075,0.001122335,0.00015792786],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017845263,0.000083352534,0.0003678071,0.0023019572,0.0000035135956,0.000002839574,0.00012450173,0.0000012731538,0.00025702972,0.00084116106,0.00086320733,0.9951355],"study_design_scores_gemma":[0.00033208783,0.00009111791,0.00026673224,0.004057275,0.000016358259,0.000021369726,0.000366697,0.00006380057,0.00012748537,0.0053796303,0.989071,0.00020642465],"about_ca_topic_score_codex":0.00003339434,"about_ca_topic_score_gemma":0.000047184993,"teacher_disagreement_score":0.9949291,"about_ca_system_score_codex":0.000046111018,"about_ca_system_score_gemma":0.0006189775,"threshold_uncertainty_score":0.5254652},"labels":[],"label_agreement":null},{"id":"W1488332973","doi":"10.1001/jamapsychiatry.2014.3246","title":"Anti-inflammatory Intervention in Depression","year":2015,"lang":"en","type":"letter","venue":"JAMA Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Depression (economics); Medicine; Intervention (counseling); Psychology; Psychiatry","score_opus":0.020387649506169243,"score_gpt":0.270641070032681,"score_spread":0.2502534205265118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1488332973","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.19591823,0.0029142105,0.00006644538,0.7501469,0.016827673,0.0010958976,0.000094172785,0.0005381202,0.032398306],"genre_scores_gemma":[0.053762138,0.00009029462,0.00021133924,0.93586963,0.0060320366,0.000076207405,0.00011378064,0.00015073146,0.003693812],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974031,0.00032386932,0.00048023724,0.00077308493,0.0005534302,0.00046627055],"domain_scores_gemma":[0.9989572,0.0000780749,0.00028519914,0.00058383547,0.000026777238,0.00006890648],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024939282,0.00034084526,0.0003423302,0.00041026025,0.000059173268,0.00013310055,0.0006474259,0.0010114057,0.00020599092],"category_scores_gemma":[0.00024133782,0.00032108446,0.00022390252,0.00030688258,0.00009078295,0.000296451,0.0001439852,0.0021123774,0.0005006746],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027347576,0.00009054675,0.0042328327,0.00020728687,0.000003562603,0.00013158702,0.00006757391,0.0000035638411,0.0005023749,0.000055083176,0.9897271,0.0049511534],"study_design_scores_gemma":[0.0023491713,0.000045043285,0.008547988,0.00063756306,0.000008424941,0.000037726255,0.000055177494,0.00004708831,0.0009528943,0.004340548,0.98247534,0.00050303317],"about_ca_topic_score_codex":0.000023915158,"about_ca_topic_score_gemma":0.00004307903,"teacher_disagreement_score":0.18572272,"about_ca_system_score_codex":0.00007738932,"about_ca_system_score_gemma":0.00014947918,"threshold_uncertainty_score":0.9999241},"labels":[],"label_agreement":null},{"id":"W1492384170","doi":"10.1139/jpn.0932","title":"Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures","year":2009,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Molecular biology; Medicine; Biology","score_opus":0.014124979150621114,"score_gpt":0.30354890989274425,"score_spread":0.28942393074212314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1492384170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945917,0.0012102724,0.000020387532,0.003504256,0.0004484576,0.0001595048,0.0000048289903,0.000010912795,0.000049638245],"genre_scores_gemma":[0.99688494,0.00046760112,0.00046360467,0.0019617304,0.000023863766,9.0352665e-7,5.4602836e-8,0.000010613582,0.00018670724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980927,0.00024040078,0.0006104457,0.00039930953,0.0003802055,0.00027690595],"domain_scores_gemma":[0.9991545,0.00008354968,0.0003455193,0.00015434729,0.000035503363,0.00022656348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050543563,0.00018736004,0.00032470698,0.00071977905,0.00008581195,0.00003181785,0.0002614337,0.000068005174,0.000012563334],"category_scores_gemma":[0.0008039895,0.00015715923,0.000058571106,0.0015082962,0.00022926304,0.00028363557,0.00006022474,0.0002269402,0.0000013445281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028354712,0.00036638867,0.001514068,0.000012141349,7.215598e-7,0.00005690187,0.00055120164,0.00009012162,0.99246407,0.00011410772,0.00035958298,0.0016352126],"study_design_scores_gemma":[0.005136634,0.0018444008,0.3479654,0.00029216145,0.000009749198,0.00025873285,0.000121527984,0.00025203565,0.6422996,0.0006441769,0.00086572685,0.0003098983],"about_ca_topic_score_codex":0.000018525587,"about_ca_topic_score_gemma":0.000030332254,"teacher_disagreement_score":0.3501645,"about_ca_system_score_codex":0.000053675714,"about_ca_system_score_gemma":0.00015730693,"threshold_uncertainty_score":0.64087677},"labels":[],"label_agreement":null},{"id":"W1498582873","doi":"10.1139/jpn.0335","title":"Plasma nitrate levels in deficit versus non-deficit forms of schizophrenia","year":2003,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Nitrate; Psychology; Psychiatry; Chemistry","score_opus":0.03427066081237833,"score_gpt":0.2751001461774358,"score_spread":0.24082948536505744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1498582873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951905,0.00013394402,0.00017328707,0.00026822393,0.0020718114,0.0000972665,0.0000073274537,0.0000069052007,0.0020507048],"genre_scores_gemma":[0.9987683,0.0001642408,0.0006883061,0.00030120768,0.000031729833,0.0000010218747,3.2603893e-8,0.000011446512,0.00003371134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822354,0.00010937663,0.00058548903,0.00031448714,0.000423317,0.00034375765],"domain_scores_gemma":[0.9990039,0.00018794216,0.0004507423,0.00017466137,0.00003704959,0.00014570064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041999578,0.00017641862,0.0002812015,0.00031660602,0.00013579222,0.000059116865,0.00041160118,0.000067510555,0.000016202644],"category_scores_gemma":[0.00069456064,0.00014106899,0.00010661288,0.0008679108,0.00030227072,0.0005399645,0.000034548644,0.00036743243,0.00000319736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001063415,0.0005649242,0.017727865,0.00007583741,0.0000028785976,0.000055483066,0.00016580263,0.0004921688,0.9343199,0.044167325,0.00007413821,0.0012902251],"study_design_scores_gemma":[0.02407177,0.0054929573,0.2836245,0.00046070642,0.00004411029,0.0015494403,0.0012807817,0.0013125183,0.65218145,0.027882418,0.0009960925,0.0011032613],"about_ca_topic_score_codex":0.0000019775814,"about_ca_topic_score_gemma":0.000023103878,"teacher_disagreement_score":0.28213847,"about_ca_system_score_codex":0.000012521018,"about_ca_system_score_gemma":0.00026585342,"threshold_uncertainty_score":0.57526267},"labels":[],"label_agreement":null},{"id":"W1498962687","doi":"10.3389/fnins.2015.00229","title":"Role of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesity","year":2015,"lang":"en","type":"review","venue":"Frontiers in Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":178,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Institut National de la Recherche Agronomique","keywords":"Neuroinflammation; Obesity; Mood disorders; Mood; Context (archaeology); Medicine; Bioinformatics; Cognition; Diabetes mellitus; Inflammation; Psychology; Neuroscience; Clinical psychology; Psychiatry; Immunology; Internal medicine; Anxiety; Endocrinology; Biology","score_opus":0.04280396576364642,"score_gpt":0.29648690924605786,"score_spread":0.25368294348241144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1498962687","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.054601554,0.9369425,0.002897414,0.00009111644,0.0006315922,0.0026882053,0.0008392754,0.000027125341,0.0012812057],"genre_scores_gemma":[0.20879593,0.79079455,0.0001419311,0.00011084047,0.000018153596,0.000063833766,0.000022032718,0.000022039869,0.000030696658],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9975753,0.00059949164,0.0005360611,0.00055214996,0.0005047598,0.00023227501],"domain_scores_gemma":[0.99907494,0.00027505858,0.0003600198,0.000203952,0.000035812478,0.000050218314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004145746,0.00022014482,0.0005894034,0.00030528966,0.000072893585,0.00004387268,0.0005742354,0.000090516514,0.0000011336855],"category_scores_gemma":[0.0007190669,0.00016992299,0.00008275799,0.0010643855,0.0006282881,0.0004292188,0.00010645636,0.00030106102,4.6208567e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029486275,0.003556787,0.0020049575,0.009405371,0.000015167476,0.00008285477,0.009121795,0.00096597994,0.05694775,0.020655362,0.0061285305,0.89082056],"study_design_scores_gemma":[0.012898822,0.0058861086,0.0322216,0.034266245,0.001039083,0.00092188554,0.007048124,0.5057754,0.019868165,0.09080886,0.2811621,0.008103614],"about_ca_topic_score_codex":0.000010809565,"about_ca_topic_score_gemma":0.0000059094264,"teacher_disagreement_score":0.88271695,"about_ca_system_score_codex":0.000024078932,"about_ca_system_score_gemma":0.00018918594,"threshold_uncertainty_score":0.6929258},"labels":[],"label_agreement":null},{"id":"W1502403473","doi":"10.1300/j018v21n03_03","title":"Psychogeriatric Patients Have a Lower Cancer Prevalence Than Nonpsychiatric Geriatric Patients","year":2000,"lang":"en","type":"article","venue":"Clinical Gerontologist","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton","funders":"","keywords":"Autopsy; Medicine; Geriatric psychiatry; Malignancy; General hospital; Cancer; Psychiatry; Mental hospital; Mental health; Internal medicine; Geriatrics; University hospital; Psychiatric hospital; Pediatrics","score_opus":0.04875632753944604,"score_gpt":0.3526773449126518,"score_spread":0.30392101737320576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1502403473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97439575,0.0006949497,0.000025310395,0.00035625964,0.0034886943,0.00093005574,0.0001541711,0.00024274399,0.019712038],"genre_scores_gemma":[0.9886559,0.0027994537,0.00022487255,0.0026022408,0.00053197023,0.00012078172,0.00001289997,0.000052193154,0.0049996544],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99518085,0.00052830356,0.0012470514,0.0015280012,0.0006136864,0.0009020905],"domain_scores_gemma":[0.99760014,0.00062663615,0.00043293711,0.00085853913,0.000106571875,0.00037515923],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00031597094,0.00045961485,0.00057945045,0.00013960218,0.00029826068,0.00010627806,0.0010860988,0.0003883961,0.0042834408],"category_scores_gemma":[0.0012761247,0.00038836294,0.000460651,0.0007292514,0.00059411925,0.00030726034,0.00011127993,0.0005388376,0.0013873692],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008857371,0.0040797847,0.78814006,0.000060341612,0.000024987203,0.000010129115,0.00007777039,0.000014442173,0.000017931097,0.000043205902,0.0256074,0.1810382],"study_design_scores_gemma":[0.0043683928,0.0010097167,0.9698458,0.00002515676,0.000060353927,0.0000012293265,0.000008287422,0.00007426116,0.0000496542,0.00027141222,0.023672514,0.0006132491],"about_ca_topic_score_codex":0.00011215498,"about_ca_topic_score_gemma":0.00012636255,"teacher_disagreement_score":0.1817057,"about_ca_system_score_codex":0.000071869435,"about_ca_system_score_gemma":0.0001030516,"threshold_uncertainty_score":0.9998568},"labels":[],"label_agreement":null},{"id":"W1505416744","doi":"10.1074/jbc.m110300200","title":"Functional Analysis of Tryptophans α62 and β120 on HLA-DM","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Medical Research Council; Pfizer Canada; Cancer Research Society; Pfizer","keywords":"Human leukocyte antigen; Immunology; Biology; Antigen","score_opus":0.060666137548835465,"score_gpt":0.2536156909038495,"score_spread":0.19294955335501404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1505416744","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945887,0.00022439183,0.000055079712,0.0003554183,0.000046890967,0.000018705405,0.000014639559,0.0000082679435,0.004687942],"genre_scores_gemma":[0.99888736,0.0002819079,0.00004270501,0.000406123,0.00008735872,5.69133e-7,0.0000011953323,0.0000031059008,0.00028965963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910563,0.000038809554,0.00032284964,0.0001766417,0.00022143793,0.00013461444],"domain_scores_gemma":[0.9991986,0.0003005829,0.0002614817,0.00009757052,0.000039398044,0.00010235884],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00010332887,0.00010462956,0.0002903951,0.00007245753,0.000043850727,0.000013735095,0.00015390756,0.00011638807,0.0020239262],"category_scores_gemma":[0.00057919795,0.000068149275,0.00022301954,0.00039065978,0.00019788799,0.000040829254,0.000028335233,0.00021444204,0.000005373779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009558867,0.00023695324,0.0018619867,0.000009511481,0.00006896497,0.000021958083,0.000025010348,0.00009044366,0.99544615,0.000059532536,0.0007199239,0.0013639645],"study_design_scores_gemma":[0.0006812558,0.00027738503,0.032999977,0.000015299998,0.0000709164,0.00006860684,0.00007804943,0.00035937846,0.9637173,0.00030775816,0.0012948643,0.00012920197],"about_ca_topic_score_codex":3.6527774e-7,"about_ca_topic_score_gemma":9.626611e-8,"teacher_disagreement_score":0.031728856,"about_ca_system_score_codex":0.000015531396,"about_ca_system_score_gemma":0.000007704512,"threshold_uncertainty_score":0.9988884},"labels":[],"label_agreement":null},{"id":"W1520134753","doi":"10.1002/9781118314814.ch24","title":"An Inflammatory Perspective of Stress and Human Depressive Disorder","year":2013,"lang":"en","type":"other","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Stressor; Neurochemical; Inflammation; Major depressive disorder; Depression (economics); Proinflammatory cytokine; Psychology; Cytokine; Perspective (graphical); Medicine; Immunology; Clinical psychology; Psychiatry; Cognition; Neuroscience","score_opus":0.010765841983320572,"score_gpt":0.2654850717141135,"score_spread":0.2547192297307929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1520134753","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.046546046,0.00045524997,0.000055588484,0.000034825225,0.000075234224,0.00050356955,0.000094621355,0.00019923162,0.9520356],"genre_scores_gemma":[0.45704782,0.00014267079,0.00006473657,0.00016561094,0.0001075067,0.000037678794,0.000006745972,0.00032309943,0.5421041],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897105,0.0000760445,0.00012877709,0.00047396548,0.00017473358,0.00017542635],"domain_scores_gemma":[0.99933636,0.000041175168,0.0001644318,0.00035393337,0.000023327599,0.000080799415],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000016185379,0.0002170221,0.00023132606,0.0001824698,0.00005165926,0.000034731514,0.00026777276,0.00017715829,0.0041370727],"category_scores_gemma":[0.000047930906,0.00017836019,0.000041094536,0.00007132893,0.0003936657,0.0000932176,0.00007331952,0.00013384888,0.000027614307],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028555749,0.0010860912,0.012283606,0.00072112336,0.000111223046,0.00003602942,0.0032864453,0.00001049859,0.11560582,0.67120355,0.19225337,0.0033736588],"study_design_scores_gemma":[0.014974777,0.0023000285,0.0942415,0.0024376055,0.0002449362,0.000039614093,0.04086982,0.0004220009,0.48639876,0.03331788,0.3161326,0.008620479],"about_ca_topic_score_codex":0.0011679712,"about_ca_topic_score_gemma":0.00081247825,"teacher_disagreement_score":0.6378857,"about_ca_system_score_codex":0.000009580963,"about_ca_system_score_gemma":0.000021337728,"threshold_uncertainty_score":0.9967733},"labels":[],"label_agreement":null},{"id":"W1521369411","doi":"10.1212/wnl.84.14_supplement.p4.080","title":"The interactive effects of Ketamine and Magnesium on Brain-Derived Neurotrophic Factor (BDNF) and depressive-like behavior (P4.080)","year":2015,"lang":"en","type":"article","venue":"Neurology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Brain-derived neurotrophic factor; Ketamine; Neurotrophic factors; Magnesium; Neuroscience; Depressive symptoms; Medicine; Psychology; Internal medicine; Anesthesia; Chemistry; Cognition; Receptor","score_opus":0.020161900279108823,"score_gpt":0.2590439237369228,"score_spread":0.23888202345781398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1521369411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957657,0.00013344601,0.000009846511,0.0026478902,0.0006731268,0.0004847367,0.000008581539,0.000045138317,0.00023153644],"genre_scores_gemma":[0.9923796,0.000051779458,0.0000041850444,0.007382612,0.000037159178,0.000050405044,5.9935223e-7,0.000025713118,0.00006791154],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99838305,0.0004750448,0.00017591273,0.0004949511,0.00017422644,0.00029684167],"domain_scores_gemma":[0.99669355,0.002706971,0.00013719156,0.0002904203,0.000035059722,0.00013681255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047648686,0.00020109577,0.00022733754,0.00008557186,0.00011760168,0.000036544156,0.0002316622,0.00009506862,0.000006194488],"category_scores_gemma":[0.0016263423,0.00014425063,0.00003753901,0.00010790491,0.0005699379,0.000100126126,0.00018400533,0.00031926806,0.00000817761],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011368023,0.00017637142,0.0055823224,0.000034387715,0.000004750593,0.00023727652,0.00044681676,0.00000383876,0.9854657,0.0002587983,0.00023837677,0.006414541],"study_design_scores_gemma":[0.0034721098,0.0063259453,0.70530665,0.0000075507855,0.000026431351,0.00023969059,0.000015530413,0.00022225721,0.28162616,0.00035862002,0.0021469109,0.00025216318],"about_ca_topic_score_codex":0.000025772633,"about_ca_topic_score_gemma":0.000021812913,"teacher_disagreement_score":0.70383954,"about_ca_system_score_codex":0.0000048413303,"about_ca_system_score_gemma":0.000023792622,"threshold_uncertainty_score":0.588237},"labels":[],"label_agreement":null},{"id":"W1526800677","doi":"10.1111/j.1524-475x.2010.00635.x","title":"Local expression of indoleamine 2,3-dioxygenase suppresses T-cell-mediated rejection of an engineered bilayer skin substitute","year":2010,"lang":"en","type":"article","venue":"Wound Repair and Regeneration","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Indoleamine 2,3-dioxygenase; CD31; Infiltration (HVAC); Immune system; Cancer research; Immunology; Keratinocyte; Wound healing; Cell; CD3; Medicine; Cell biology; Chemistry; Angiogenesis; Biology; CD8; Cell culture; Materials science","score_opus":0.009948246631120051,"score_gpt":0.22570118173490222,"score_spread":0.21575293510378218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1526800677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964287,0.00013281785,0.0026330117,0.000020717995,0.0003047131,0.00021121846,0.000016454362,0.00008776503,0.00016455445],"genre_scores_gemma":[0.9986665,0.00007105011,0.0009020462,0.000026956961,0.00009053112,0.000010742974,0.00003645466,0.000013649588,0.00018202394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990082,0.00008288501,0.0002719088,0.00030341497,0.00020496524,0.00012865935],"domain_scores_gemma":[0.99941015,0.00007575331,0.000120280914,0.00025848026,0.00006108131,0.00007424822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013723338,0.00012555532,0.0001538464,0.00013281184,0.00009406362,0.000017573228,0.000078811856,0.00015672961,0.00003256841],"category_scores_gemma":[0.00015102151,0.00009906917,0.000055080352,0.00021460808,0.00018149878,0.00025415423,0.000023421502,0.00013860657,0.0000015505954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008133433,0.00020342329,0.000021387352,0.00006478541,0.0000018016908,0.0000028424115,0.00023555581,0.0007565802,0.99755687,0.00021793153,0.00011903001,0.00073846476],"study_design_scores_gemma":[0.0006742702,0.0001547175,0.0010511361,0.000018191895,0.0000039933407,0.000013094931,0.00008148853,0.009271848,0.98810697,0.000051926232,0.00045679865,0.00011553979],"about_ca_topic_score_codex":0.000044023207,"about_ca_topic_score_gemma":0.00009982064,"teacher_disagreement_score":0.0094498675,"about_ca_system_score_codex":0.000006540896,"about_ca_system_score_gemma":0.00004022596,"threshold_uncertainty_score":0.40399235},"labels":[],"label_agreement":null},{"id":"W155900023","doi":"10.1159/000468311","title":"Transmethylation Hypothesis of Schizophrenia: Methionine andNicotinic Acid","year":2017,"lang":"en","type":"review","venue":"International Pharmacopsychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Transmethylation; Nicotinic agonist; Schizophrenia (object-oriented programming); Exacerbation; Methionine; Medicine; Psychopathology; Monoamine oxidase; Psychiatry; Internal medicine; Pharmacology; Biochemistry; Chemistry; Amino acid","score_opus":0.17632396046803162,"score_gpt":0.42197470881707544,"score_spread":0.24565074834904382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W155900023","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007332751,0.98175836,0.00012322342,0.00039165793,0.0053779865,0.000547663,0.00043468407,0.00009430392,0.011198823],"genre_scores_gemma":[0.002333305,0.9946114,0.0012072587,0.00017914563,0.0007308777,0.000039868908,0.00004330581,0.000080366946,0.00077448523],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971442,0.00029457072,0.00094561314,0.0007082224,0.0006412376,0.00026614734],"domain_scores_gemma":[0.9975901,0.0005004713,0.0012196286,0.000510145,0.00007341089,0.00010624919],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003033244,0.00047107792,0.0010989337,0.00049722317,0.0001602109,0.000095023956,0.0017868573,0.00027391294,0.0011570447],"category_scores_gemma":[0.0005069789,0.0004087454,0.00095847045,0.00023764344,0.00019712214,0.00031702,0.000112203146,0.0006140696,0.00026070737],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006981707,0.00018473102,0.0000015669606,0.0018135377,0.00016704579,0.0000046600057,0.00002322457,0.0000016396433,0.0010459914,0.0012198524,0.0013117078,0.99415624],"study_design_scores_gemma":[0.0011096195,0.000034119163,0.000012344774,0.0021614197,0.00028503448,0.000041991614,0.0000035555486,0.000023345567,0.004296021,0.0012449796,0.9903824,0.00040522014],"about_ca_topic_score_codex":0.0000055614023,"about_ca_topic_score_gemma":0.0000026584778,"teacher_disagreement_score":0.993751,"about_ca_system_score_codex":0.0000577661,"about_ca_system_score_gemma":0.00033747274,"threshold_uncertainty_score":0.99983644},"labels":[],"label_agreement":null},{"id":"W1574978600","doi":"10.1517/13543784.2015.1057675","title":"Evidence to support peripheral and central IL-6 signaling targets to treat depression","year":2015,"lang":"en","type":"letter","venue":"Expert Opinion on Investigational Drugs","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Depression (economics); Medicine; Peripheral; Investigational Drugs; Psychology; Bioinformatics; Psychiatry; Biology; Internal medicine; Clinical trial","score_opus":0.08810745822753124,"score_gpt":0.3210609034709742,"score_spread":0.23295344524344297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1574978600","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.029939326,0.001209043,0.00027966473,0.9606346,0.003416184,0.0015882908,0.0003418365,0.0003206551,0.0022704394],"genre_scores_gemma":[0.027946424,0.00022319653,0.0017200344,0.9631507,0.0041488423,0.00026326827,0.00029635432,0.00010255513,0.0021486462],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99585176,0.0003075837,0.00043753258,0.0012914342,0.0014142827,0.000697434],"domain_scores_gemma":[0.99806327,0.0005661776,0.00014212799,0.00040063396,0.000102551865,0.0007252535],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016467679,0.00052930455,0.00037748384,0.00029410355,0.00027947332,0.00022168377,0.0005328806,0.00039689324,0.0003670817],"category_scores_gemma":[0.0015056398,0.00048385764,0.0001048273,0.0003278147,0.00022154761,0.0003568568,0.00021158939,0.0007088984,0.0002592827],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000077559685,0.000026084721,0.000046893005,0.00003524073,0.000003395301,0.00003164662,0.0033109293,0.00028004605,0.034319576,0.00016413425,0.959238,0.0024665087],"study_design_scores_gemma":[0.00045523304,0.00035036344,0.00031213684,0.0007468007,0.0000016783148,0.00002716012,0.00009857786,0.00012236767,0.056386426,0.00090636447,0.9398834,0.0007095004],"about_ca_topic_score_codex":0.000051202634,"about_ca_topic_score_gemma":8.961016e-7,"teacher_disagreement_score":0.022066848,"about_ca_system_score_codex":0.00025982442,"about_ca_system_score_gemma":0.00041695274,"threshold_uncertainty_score":0.9997613},"labels":[],"label_agreement":null},{"id":"W1585166895","doi":"10.1111/j.1365-2133.2011.10489.x","title":"CXCR3 ligands promote expression of functional indoleamine 2,3-dioxygenase in basal cell carcinoma keratinocytes","year":2011,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Hospital and Health Sciences Centre; Vancouver General Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Indoleamine 2,3-dioxygenase; Downregulation and upregulation; Basal cell carcinoma; Kynurenine; Biology; Keratinocyte; Cancer research; CXCR3; Carcinogenesis; Western blot; Molecular biology; Immunology; Immune system; In vitro; Biochemistry; Medicine; Pathology; Chemokine; Gene; Basal cell","score_opus":0.02788231292972241,"score_gpt":0.2188410864020706,"score_spread":0.1909587734723482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1585166895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99746233,0.0008132366,0.00018163334,0.00006886269,0.00023421206,0.00009472589,0.000010110871,0.000008274974,0.0011265818],"genre_scores_gemma":[0.9991724,0.00009506896,0.00040956237,0.00021099937,0.00004563103,0.0000030135675,0.0000014207831,0.00001499125,0.000046893736],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851865,0.000154656,0.0006452327,0.00019149062,0.00023472944,0.0002552272],"domain_scores_gemma":[0.9991988,0.00010865389,0.00040018783,0.00010377638,0.00008741895,0.00010114532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001053962,0.000121020705,0.00034280107,0.00022475285,0.000057656256,0.000017807139,0.00025435232,0.00011886321,0.00019334414],"category_scores_gemma":[0.00026294397,0.00012743018,0.000104578794,0.00020563457,0.00015715924,0.00025360787,0.000062549945,0.00033025813,0.0000074226828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003544181,0.00070259173,0.012216719,0.00007068279,0.000003300372,0.0049340157,0.0005746427,0.000007349352,0.97697514,0.000059743223,0.0020923482,0.0020090688],"study_design_scores_gemma":[0.002252064,0.00013323317,0.08070497,0.00009009505,0.0000025778952,0.012543492,0.0001267627,0.000037679576,0.9036109,0.0003209569,0.000070820024,0.00010648759],"about_ca_topic_score_codex":0.000026035887,"about_ca_topic_score_gemma":0.000023967777,"teacher_disagreement_score":0.073364265,"about_ca_system_score_codex":0.0000143850175,"about_ca_system_score_gemma":0.000112120506,"threshold_uncertainty_score":0.51964515},"labels":[],"label_agreement":null},{"id":"W1588655866","doi":"10.1111/cei.12396","title":"Soluble CD40-ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection","year":2014,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Kynurenine; Regulatory T cell; CD40; Immunology; Peripheral blood mononuclear cell; T cell; Immune system; CD8; Biology; IL-2 receptor; Cytotoxic T cell; In vitro; Biochemistry","score_opus":0.026181124155362015,"score_gpt":0.32253036373414545,"score_spread":0.29634923957878345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1588655866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945598,0.0008218449,0.00010812475,0.00010337325,0.0016363978,0.00036729366,0.000003202845,0.00017583629,0.0022241077],"genre_scores_gemma":[0.9981727,0.00015699309,0.00011379111,0.0008916024,0.0001413278,0.000071955845,0.000022005173,0.000050942224,0.00037866915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964026,0.00090745854,0.0008650731,0.0009850782,0.00021300603,0.0006267657],"domain_scores_gemma":[0.9983592,0.00041708277,0.0002746497,0.0007825142,0.000027238835,0.00013930528],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039713318,0.00033256283,0.00051620207,0.00018136502,0.0002536697,0.000058443773,0.0005022473,0.00047835728,0.0002118691],"category_scores_gemma":[0.0002925798,0.00032919538,0.00018964423,0.00023881123,0.0007385174,0.00053983956,0.000357676,0.0006498249,0.00048450808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041554726,0.00180771,0.002467762,0.000005126523,0.0000070527567,0.000009881283,0.00064146216,0.000028417619,0.9911873,0.0004944911,0.0002289468,0.0027063177],"study_design_scores_gemma":[0.003682529,0.0014383261,0.022476565,0.000026155394,0.0000051390925,0.000019941092,0.0005977943,0.0008556776,0.9675988,0.0007535254,0.002169619,0.00037590635],"about_ca_topic_score_codex":0.00012600987,"about_ca_topic_score_gemma":0.000021192374,"teacher_disagreement_score":0.023588464,"about_ca_system_score_codex":0.0000917365,"about_ca_system_score_gemma":0.000055352233,"threshold_uncertainty_score":0.999916},"labels":[],"label_agreement":null},{"id":"W1591925493","doi":"10.1179/1476830515y.0000000034","title":"Western diet-induced anxiolytic effects in mice are associated with alterations in tryptophan metabolism","year":2015,"lang":"en","type":"article","venue":"Nutritional Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Endocrinology; Internal medicine; Tryptophan hydroxylase; Elevated plus maze; Tryptophan; Serotonin; Anxiolytic; Brain-derived neurotrophic factor; Chemistry; Neurotrophic factors; Biology; Serotonergic; Medicine; Biochemistry; Amino acid; Anxiety; Receptor","score_opus":0.04639954600320893,"score_gpt":0.27471045139761696,"score_spread":0.22831090539440801,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1591925493","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975276,0.00007897326,0.00007507221,0.0010343055,0.00038281275,0.0004720705,0.00003072645,0.00007456762,0.00032386533],"genre_scores_gemma":[0.996404,0.000009957456,0.00006011021,0.0032566695,0.00005578438,0.000111665395,0.0000055796836,0.000019902109,0.00007636246],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99746877,0.00034240662,0.00027711102,0.0006439881,0.0006991064,0.0005685977],"domain_scores_gemma":[0.9989549,0.0004544943,0.00012474958,0.00017989188,0.00005332673,0.00023261765],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025185285,0.00022182327,0.0002584813,0.0003440659,0.00012419521,0.00011749096,0.00040287132,0.00007730772,0.0000039488896],"category_scores_gemma":[0.0019782456,0.00020504059,0.00004161171,0.0018055722,0.00021323109,0.000748043,0.00006639177,0.00031325777,0.000022443617],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038956665,0.0029435277,0.037572194,0.00004421831,0.0000016148407,0.00037742563,0.00066680956,0.0010580465,0.9525907,0.004048979,0.00017977454,0.00012715632],"study_design_scores_gemma":[0.0050173556,0.00036974018,0.8907447,0.00023154577,0.0000054938264,0.00004753886,0.00010723383,0.0026394122,0.098154396,0.0019742816,0.00024620089,0.0004620877],"about_ca_topic_score_codex":0.000024628276,"about_ca_topic_score_gemma":0.0002525743,"teacher_disagreement_score":0.8544363,"about_ca_system_score_codex":0.00010320609,"about_ca_system_score_gemma":0.00013252642,"threshold_uncertainty_score":0.8361313},"labels":[],"label_agreement":null},{"id":"W1600644808","doi":"10.1111/j.1365-2893.2010.01408.x","title":"Persistent pro‐inflammatory cytokines following the initiation of pegylated IFN therapy in hepatitis C infection is associated with treatment‐induced depression","year":2010,"lang":"en","type":"article","venue":"Journal of Viral Hepatitis","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Depression (economics); Cytokine; Medicine; Peripheral blood mononuclear cell; Internal medicine; Tumor necrosis factor alpha; Beck Depression Inventory; In vivo; Endocrinology; Pegylated interferon; Immunology; Gastroenterology; Chronic hepatitis; Virus; Biology; In vitro; Ribavirin; Anxiety; Psychiatry","score_opus":0.024405714237924057,"score_gpt":0.26555426885557853,"score_spread":0.24114855461765447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1600644808","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987866,0.00005068588,0.0000095534615,0.00020038884,0.00038942817,0.00030497136,0.000008307445,0.000018381936,0.00023166245],"genre_scores_gemma":[0.9991563,0.00053186464,0.000022786766,0.00015861596,0.00006382798,0.000012693245,0.0000025040176,0.000019659694,0.00003176982],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99852425,0.00022220999,0.00046933262,0.00016537227,0.00042783038,0.00019098987],"domain_scores_gemma":[0.99884355,0.00019105665,0.00065035466,0.00014405773,0.000120069584,0.000050903316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023697867,0.00016628498,0.0002714876,0.00020838855,0.00014275554,0.000046772995,0.00014584954,0.000117441006,0.00005753605],"category_scores_gemma":[0.00033149833,0.000101576275,0.00023623952,0.00035134962,0.00006223363,0.0004955382,0.000015312986,0.00030818817,0.0000018465291],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001396931,0.00022804075,0.6080667,0.000004844144,0.000048857226,0.000055932574,0.0014402325,0.00003182372,0.37782913,0.000010650508,0.000028023826,0.012116102],"study_design_scores_gemma":[0.002465134,0.0014978108,0.6875348,0.00014049695,0.000025496018,0.00004005538,0.00003549369,0.0004820099,0.3074863,0.00009724478,0.00007561644,0.00011950765],"about_ca_topic_score_codex":0.0008494278,"about_ca_topic_score_gemma":0.0034794924,"teacher_disagreement_score":0.07946816,"about_ca_system_score_codex":0.00010975087,"about_ca_system_score_gemma":0.00011990272,"threshold_uncertainty_score":0.41421604},"labels":[],"label_agreement":null},{"id":"W1606036403","doi":"10.1016/j.ajpath.2011.05.048","title":"The Tryptophan Metabolite 3-Hydroxyanthranilic Acid Plays Anti-Inflammatory and Neuroprotective Roles During Inflammation","year":2011,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":173,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Allergy and Infectious Diseases; Center for AIDS Research, University of Washington; National Institutes of Health; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Deutsche Forschungsgemeinschaft","keywords":"Quinolinic acid; Neurotoxicity; Microglia; Neuroprotection; Biology; Proinflammatory cytokine; Kynurenine pathway; Cytokine; Neuroinflammation; Inflammation; Pharmacology; Kynurenine; Immunology; Biochemistry; Medicine; Tryptophan; Internal medicine; Toxicity","score_opus":0.012042267382220652,"score_gpt":0.22475998249202256,"score_spread":0.21271771510980192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1606036403","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998532,0.00029501945,0.00026282232,0.00020770823,0.00015882424,0.00012092027,0.0000029249215,0.00002403619,0.00039573936],"genre_scores_gemma":[0.9988059,0.0006931467,0.00019670451,0.00015262877,0.00011485982,0.000005662354,8.5997314e-8,0.000020530357,0.000010476569],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983042,0.0005364015,0.00042391388,0.00022935952,0.00019696042,0.00030916688],"domain_scores_gemma":[0.9987762,0.000170762,0.0006879724,0.00019736888,0.000062084306,0.00010559218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032473105,0.00016503688,0.00031005475,0.00016574349,0.00029086205,0.000034147688,0.0003176275,0.000040307008,0.000011558848],"category_scores_gemma":[0.00051169004,0.0001143502,0.00009430921,0.00023791617,0.0011096704,0.00025877796,0.00007368698,0.00034247455,0.000008915515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019771665,0.000022880005,0.0012038331,0.0000053205104,0.000011997667,0.0003957325,0.0025876886,0.000005673322,0.9737291,0.0010389987,0.0000015276894,0.020799577],"study_design_scores_gemma":[0.00067120144,0.00045660877,0.18340652,0.000010749693,0.000016240881,0.0023702774,0.0013985275,0.000027117216,0.81018907,0.001192956,0.000121949946,0.00013880899],"about_ca_topic_score_codex":0.0000034548016,"about_ca_topic_score_gemma":0.000004546228,"teacher_disagreement_score":0.1822027,"about_ca_system_score_codex":0.000014981235,"about_ca_system_score_gemma":0.000041281673,"threshold_uncertainty_score":0.46630657},"labels":[],"label_agreement":null},{"id":"W1609991223","doi":"10.1139/jpn.0935","title":"3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder","year":2009,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":199,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Young Mania Rating Scale; Bipolar disorder; Glutathione; Glutathione reductase; Glutathione peroxidase; Internal medicine; Nitrotyrosine; Mania; Oxidative stress; Stage (stratigraphy); Psychology; Medicine; Psychiatry; Gastroenterology; Mood; Chemistry; Enzyme; Biochemistry; Superoxide dismutase; Biology; Nitric oxide","score_opus":0.010026659052256612,"score_gpt":0.23622546619786697,"score_spread":0.22619880714561036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1609991223","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975537,0.0011328048,0.000023461529,0.00089492556,0.00023124614,0.00013236437,0.0000051079696,0.0000036968681,0.000022684862],"genre_scores_gemma":[0.9984221,0.0009245199,0.00007615495,0.0005545577,0.000013773091,4.3380135e-7,2.7802125e-8,0.0000034625327,0.000005003638],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987864,0.00016413182,0.00037278564,0.00020585643,0.00029374857,0.00017707236],"domain_scores_gemma":[0.9994967,0.000077808494,0.00025362658,0.00009423812,0.00001952548,0.00005812418],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040745706,0.0001064421,0.0001855365,0.00021299534,0.000097443786,0.000064106556,0.0002003351,0.000032255408,3.501136e-7],"category_scores_gemma":[0.00014162359,0.000069598886,0.000025512556,0.0004955784,0.00022372213,0.00038094886,0.000027491098,0.00021936104,9.627386e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017600994,0.000539524,0.86096287,0.00007767579,6.248073e-7,0.000021608757,0.00078878494,0.00003281254,0.13110046,0.003092887,0.000010931075,0.0031957817],"study_design_scores_gemma":[0.0011534509,0.00096041727,0.99591774,0.00011361875,0.0000033076337,0.000055948476,0.00015079771,0.00012501917,0.0009018577,0.0004892029,0.000055508935,0.00007314964],"about_ca_topic_score_codex":0.000011708607,"about_ca_topic_score_gemma":0.000013987405,"teacher_disagreement_score":0.13495483,"about_ca_system_score_codex":0.000004462423,"about_ca_system_score_gemma":0.00002700156,"threshold_uncertainty_score":0.283816},"labels":[],"label_agreement":null},{"id":"W1611362056","doi":"10.1111/j.1471-4159.2004.02434.x","title":"Brain antioxidant systems in human methamphetamine users","year":2004,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; London Health Sciences Centre; Western University; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; University of California Merced","keywords":"Methamphetamine; Oxidative stress; Dopamine; Glutathione; Uric acid; Antioxidant; Superoxide dismutase; Chemistry; Internal medicine; Endocrinology; Glutathione reductase; Dopamine receptor D1; Pharmacology; Dopaminergic; Biochemistry; Medicine; Glutathione peroxidase; Enzyme","score_opus":0.024732045977537837,"score_gpt":0.2786597297179376,"score_spread":0.25392768374039976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1611362056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975209,0.0001734337,0.000083523795,0.0009001582,0.00023414618,0.000060920785,0.0000025036568,0.000017646651,0.0010067205],"genre_scores_gemma":[0.9988267,0.000038472364,0.00004776711,0.00064947206,0.00012848945,0.0000012210463,2.6062955e-7,0.000018236575,0.00028939004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986595,0.000065189466,0.00050724635,0.00020772473,0.00031472798,0.0002456457],"domain_scores_gemma":[0.9991837,0.000132837,0.00034161314,0.00018177199,0.00003975926,0.00012030325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020424691,0.00014525624,0.00025248688,0.00012800274,0.000052027404,0.000056873483,0.00040338968,0.00007005344,0.000016196042],"category_scores_gemma":[0.00076469843,0.00013026968,0.00012049353,0.00031976806,0.0000874915,0.00017637694,0.000038383925,0.00038483852,0.0000048039515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002144158,0.00015191354,0.000210419,0.000047581965,0.0000029244502,0.00047067564,0.000079970516,0.0011591552,0.9973466,0.00014796133,0.00028966775,0.00007173583],"study_design_scores_gemma":[0.0025375595,0.00014667377,0.010247022,0.00017432768,0.00000544993,0.0014168341,0.0002536664,0.000015890615,0.98296934,0.0006395053,0.0013965137,0.00019720274],"about_ca_topic_score_codex":0.0000073891124,"about_ca_topic_score_gemma":0.0000013689569,"teacher_disagreement_score":0.014377198,"about_ca_system_score_codex":0.000066559405,"about_ca_system_score_gemma":0.000081328355,"threshold_uncertainty_score":0.5312243},"labels":[],"label_agreement":null},{"id":"W1660594009","doi":"10.1139/jpn.0704","title":"Platelet serotonin levels support depression scores for women with postpartum depression","year":2007,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; University of British Columbia","funders":"","keywords":"Depression (economics); Serotonin; Postpartum depression; Platelet; Medicine; Internal medicine; Clinical psychology; Psychology; Psychiatry; Pregnancy; Biology; Receptor","score_opus":0.02411474461463245,"score_gpt":0.2861366528877901,"score_spread":0.26202190827315763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1660594009","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936063,0.0000909127,0.0039667534,0.00055549346,0.0011622949,0.00026113295,0.000011084055,0.000021655693,0.00032432502],"genre_scores_gemma":[0.9961168,0.00006122119,0.001342119,0.0021259836,0.00013604481,0.0000053762856,1.18009844e-7,0.000017363835,0.0001949848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981683,0.00005152543,0.00040388503,0.0003975748,0.00047411493,0.0005046357],"domain_scores_gemma":[0.9988291,0.00020477742,0.0004258909,0.00017145526,0.000056531208,0.00031222336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006864598,0.00018191386,0.00021952417,0.00019782488,0.00035405625,0.000103746184,0.00040805133,0.000065563625,0.000018299566],"category_scores_gemma":[0.00027986185,0.00012199783,0.000055659348,0.00035057336,0.00026242482,0.00062503235,0.000058769518,0.00025444245,0.000001191022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028231093,0.00032882832,0.07199853,0.00009108885,0.0000026735506,0.00009648508,0.00041484679,0.000074889984,0.9154296,0.00040923746,0.0008133926,0.0075173117],"study_design_scores_gemma":[0.002977234,0.0029381865,0.35543728,0.00017880336,0.000008079621,0.0020232773,0.00031063633,0.00011205653,0.62878865,0.0020048828,0.004888112,0.00033276674],"about_ca_topic_score_codex":6.41446e-7,"about_ca_topic_score_gemma":0.0000058952833,"teacher_disagreement_score":0.28664094,"about_ca_system_score_codex":0.000015978077,"about_ca_system_score_gemma":0.00017045393,"threshold_uncertainty_score":0.4974927},"labels":[],"label_agreement":null},{"id":"W171179939","doi":"10.1159/000468501","title":"The Use of Nicotinic Acid and Pyridoxine in theTreatment of Schizophrenia","year":2017,"lang":"en","type":"article","venue":"International Pharmacopsychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Pyridoxine; Nicotinic agonist; Medicine; Schizophrenia (object-oriented programming); Pharmacology; Vitamin b6; Therapeutic effect; Vitamin; Internal medicine; Psychiatry; Receptor","score_opus":0.058755505387187754,"score_gpt":0.3319890950929191,"score_spread":0.2732335897057313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W171179939","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99368054,0.00022976872,0.000008122319,0.003309117,0.001156997,0.00012330449,0.000039994753,0.000008094757,0.0014440395],"genre_scores_gemma":[0.9988188,0.00049229816,0.00019247536,0.00020540773,0.000058092246,0.0000071622912,8.6699356e-7,0.000007478352,0.00021738182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925584,0.000037943166,0.00023196511,0.0001704084,0.00020185258,0.00010197572],"domain_scores_gemma":[0.9993006,0.00016702812,0.00024501793,0.00023257521,0.000026227208,0.000028564556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008592792,0.00008303359,0.00009430271,0.00006151261,0.00010813664,0.000058255733,0.0004764595,0.000021211836,0.000051628955],"category_scores_gemma":[0.00024231813,0.00005797591,0.000050420193,0.000040084822,0.0002553915,0.00021626132,0.00012269315,0.000089736895,0.0000049132973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016621809,0.0008073942,0.08153916,0.000035067744,0.00009221631,0.000008333911,0.00028515462,0.00010468844,0.8199093,0.02854363,0.0029500574,0.06406282],"study_design_scores_gemma":[0.0066952137,0.000116560186,0.23637596,0.00010296362,0.00001516917,0.00001726082,0.00006092445,0.0024166119,0.73470926,0.005453085,0.013827256,0.00020976069],"about_ca_topic_score_codex":0.00006368066,"about_ca_topic_score_gemma":0.000056836103,"teacher_disagreement_score":0.1548368,"about_ca_system_score_codex":0.000010798019,"about_ca_system_score_gemma":0.00003082142,"threshold_uncertainty_score":0.2364189},"labels":[],"label_agreement":null},{"id":"W1715244398","doi":"10.1111/cge.12651","title":"Whole‐genome sequencing provides insight into the genetics of major depressive disorder","year":2015,"lang":"en","type":"letter","venue":"Clinical Genetics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pharmacogenomics; Major depressive disorder; Library science; Genome-wide association study; Psychiatry; Psychiatric genetics; Medicine; Genetics; Biology; Single-nucleotide polymorphism; Computer science; Mood; Genotype; Pharmacology","score_opus":0.08764478720738846,"score_gpt":0.3362855078231318,"score_spread":0.24864072061574338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1715244398","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3875114,0.049276713,0.0016879847,0.5378513,0.0068091224,0.0057669603,0.0007577866,0.00043069856,0.009908043],"genre_scores_gemma":[0.11913954,0.00592491,0.0024401569,0.8581674,0.0070256875,0.00015677814,0.00019119587,0.00042629938,0.0065280376],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9947639,0.00094760116,0.0015086884,0.0011575908,0.00095855014,0.00066365156],"domain_scores_gemma":[0.994978,0.0020586606,0.0008817217,0.001622535,0.00027315668,0.0001859001],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00050539704,0.0005695185,0.00083796185,0.00012709631,0.00020595492,0.0001227614,0.0020689908,0.0012286126,0.000058455564],"category_scores_gemma":[0.0029071139,0.00040160542,0.0004351195,0.0004283406,0.0018481391,0.00005588909,0.00078692747,0.00236203,0.00016475625],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015180116,0.0005633824,0.003571566,0.0011262875,0.00031334136,0.0006322246,0.0078823855,0.0015315767,0.07377995,0.00009807711,0.8512266,0.05912278],"study_design_scores_gemma":[0.0009102996,0.0003590917,0.00059960195,0.000070295595,0.000120232646,0.000011153947,0.00010601258,0.00038091614,0.0049916212,0.0029956906,0.98888075,0.00057430327],"about_ca_topic_score_codex":0.00002149836,"about_ca_topic_score_gemma":0.000044923945,"teacher_disagreement_score":0.3203161,"about_ca_system_score_codex":0.000072760966,"about_ca_system_score_gemma":0.00077579304,"threshold_uncertainty_score":0.99993956},"labels":[],"label_agreement":null},{"id":"W1826495180","doi":"10.4137/ijtr.s26862","title":"Tryptophan Catabolism in Chronic Viral Infections: Handling Uninvited Guests","year":2015,"lang":"en","type":"review","venue":"International Journal of Tryptophan Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Immune system; Kynurenine; Indoleamine 2,3-dioxygenase; Biology; Aryl hydrocarbon receptor; Virus; Hepatitis C virus; Immunology; Immunosuppression; Virology; Tryptophan; Amino acid; Biochemistry","score_opus":0.21114566067162638,"score_gpt":0.48765964293816255,"score_spread":0.2765139822665362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1826495180","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021175477,0.99212617,0.000056351233,0.00027318092,0.003135864,0.0007238012,0.00009043898,0.000041745006,0.001434933],"genre_scores_gemma":[0.0038192433,0.99237394,0.000092015965,0.000084137144,0.002786661,0.00006299057,0.00003698841,0.00011070764,0.000633304],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99101806,0.0019705966,0.0019199374,0.0007324459,0.0034185664,0.00094042154],"domain_scores_gemma":[0.99518937,0.0015260932,0.001016942,0.0005004018,0.001329911,0.00043728502],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0029711223,0.0005675096,0.0016136857,0.0049221423,0.00017004208,0.0004945707,0.0032602465,0.00052913255,0.00022264257],"category_scores_gemma":[0.0043143965,0.00048218967,0.0007122165,0.0020500198,0.0004874746,0.00077372143,0.000605189,0.0033973455,0.00030467007],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013996767,0.00063613354,0.000012452487,0.001151412,0.0001649469,0.0017376244,0.00032119176,0.00008778006,0.0008254051,0.0022102534,0.0037507867,0.98896205],"study_design_scores_gemma":[0.0021241938,0.00039183703,0.000016596308,0.008044389,0.00003301665,0.0010583233,0.00006645127,0.0000669625,0.00091296685,0.0024718035,0.9843738,0.0004396561],"about_ca_topic_score_codex":0.000084208834,"about_ca_topic_score_gemma":0.00006718673,"teacher_disagreement_score":0.9885224,"about_ca_system_score_codex":0.0028666048,"about_ca_system_score_gemma":0.004300994,"threshold_uncertainty_score":0.99976295},"labels":[],"label_agreement":null},{"id":"W1838530782","doi":"10.1158/1538-7445.am2014-3765","title":"Abstract 3765: Indoleamine 2,3-dioxygenase mediates immune-independent human tumor cell resistance to olaparib, γ radiation, and cisplatin","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Olaparib; Indoleamine 2,3-dioxygenase; Cancer research; Immune system; Cisplatin; Cancer; Cancer cell; Immunosurveillance; PARP inhibitor; DNA repair; Medicine; Biology; Immunology; Poly ADP ribose polymerase; Internal medicine; Chemotherapy; DNA; Biochemistry","score_opus":0.04319448803183638,"score_gpt":0.35010785905885977,"score_spread":0.3069133710270234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1838530782","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900934,0.0008022375,0.00001574281,0.0011492383,0.00012853822,0.00052226585,0.000060554365,0.000060472048,0.0071675396],"genre_scores_gemma":[0.9961069,0.00017603512,0.000037157195,0.0004603282,0.00021356944,0.00015715936,0.0000069959615,0.00003805602,0.002803754],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99704134,0.00027068728,0.00036682218,0.0007317799,0.0008905207,0.0006988632],"domain_scores_gemma":[0.99826825,0.000692346,0.00009725275,0.00048272606,0.00012160867,0.0003378118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012495633,0.00018749549,0.00022787903,0.0003056457,0.000501403,0.00018584145,0.000535618,0.00007226069,0.00026223424],"category_scores_gemma":[0.001389284,0.00017722319,0.0000433035,0.0006151718,0.00023454172,0.00017467655,0.00019128926,0.00051237346,0.00017700168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014077665,0.00008088769,0.0002704386,0.000096428244,0.0000029821683,0.000018860816,0.000586579,0.00003724984,0.9886392,0.0006911392,0.0068800612,0.0025554346],"study_design_scores_gemma":[0.0014283913,0.000096330725,0.052204207,0.0000572567,0.0000011444339,0.0000013089273,0.00015166006,0.000026906193,0.92564595,0.0006295263,0.019531086,0.00022624152],"about_ca_topic_score_codex":0.00025348377,"about_ca_topic_score_gemma":0.00050410477,"teacher_disagreement_score":0.06299322,"about_ca_system_score_codex":0.00013382276,"about_ca_system_score_gemma":0.00013446235,"threshold_uncertainty_score":0.7226952},"labels":[],"label_agreement":null},{"id":"W1877918830","doi":"10.1016/j.schres.2015.10.008","title":"Association study of functional polymorphisms in interleukins and interleukin receptors genes: IL1A, IL1B, IL1RN, IL6, IL6R, IL10, IL10RA and TGFB1 in schizophrenia in Polish population","year":2015,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Narodowe Centrum Nauki","keywords":"Schizophrenia (object-oriented programming); Haplotype; DISC1; Genetic association; Linkage disequilibrium; Psychosis; Immunology; Population; Gene; Allele; Medicine; Genetics; Biology; Single-nucleotide polymorphism; Genotype; Psychiatry","score_opus":0.08761235249114846,"score_gpt":0.33326049941452407,"score_spread":0.2456481469233756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1877918830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99695647,0.00034950874,0.000004145098,0.00080689363,0.00042816738,0.0010821789,0.000022715294,0.00004540843,0.00030448585],"genre_scores_gemma":[0.99901474,0.00014473837,0.00011948558,0.000079304016,0.00011798854,0.00011561239,0.000021027297,0.000048724458,0.00033839216],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99394447,0.0016917309,0.00095781684,0.0010672068,0.0014844823,0.0008543267],"domain_scores_gemma":[0.9980803,0.00081532064,0.00023626481,0.0004084893,0.00018833348,0.00027125765],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0030585607,0.0003378285,0.00055935286,0.0026685721,0.0001324058,0.00017834837,0.00043668092,0.00029363716,0.00008076885],"category_scores_gemma":[0.003144509,0.00034760803,0.000051881725,0.002709521,0.00028606306,0.00073683355,0.0004952481,0.0011742524,0.000022330398],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011240971,0.0029538204,0.9058531,0.000088759094,0.00003414235,0.000096087875,0.012836921,0.0002666729,0.025232412,0.002572653,0.0015068223,0.037317626],"study_design_scores_gemma":[0.019349007,0.0012761431,0.9564292,0.00024617717,0.000007974798,0.000012227121,0.009241655,0.0015628382,0.0031892397,0.007886052,0.00022955265,0.00056998024],"about_ca_topic_score_codex":0.006614834,"about_ca_topic_score_gemma":0.03632458,"teacher_disagreement_score":0.050576042,"about_ca_system_score_codex":0.0008534997,"about_ca_system_score_gemma":0.00028038287,"threshold_uncertainty_score":0.9999695},"labels":[],"label_agreement":null},{"id":"W1886307983","doi":"10.1038/npp.2015.274","title":"Social Stress and Psychosis Risk: Common Neurochemical Substrates?","year":2015,"lang":"en","type":"review","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":119,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation","keywords":"Neurochemical; Schizophrenia (object-oriented programming); Mechanism (biology); Psychosis; Social stress; Psychology; Neuroscience; Neuroinflammation; Psychiatry; Disease; Medicine","score_opus":0.07901998066836463,"score_gpt":0.4001187117417843,"score_spread":0.3210987310734197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1886307983","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015346512,0.97615665,0.0000010043884,0.00023183858,0.0022561883,0.0011916,0.00039984024,0.00033134656,0.004085037],"genre_scores_gemma":[0.0026219336,0.99469,0.000008320298,0.0014441661,0.00067790796,0.00018340291,0.00002967528,0.0001688794,0.0001757226],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99462163,0.0018139774,0.0007921541,0.0015810817,0.00039255756,0.00079857605],"domain_scores_gemma":[0.997686,0.0007943267,0.0006706932,0.00040037814,0.00004500511,0.00040359073],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018484231,0.0008406406,0.0018073724,0.0002963852,0.0003128943,0.000116899624,0.0009975528,0.000614812,0.00019622552],"category_scores_gemma":[0.00018244711,0.0007651513,0.00041131064,0.00075222395,0.00066073844,0.00011819844,0.00025899624,0.0019731594,0.0003018083],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012851803,0.00047533205,0.000023594666,0.0030091973,0.000052332958,0.00026080757,0.00012135762,3.6156433e-7,0.0013812323,0.00014028979,0.0490165,0.94539046],"study_design_scores_gemma":[0.0012793533,0.00015712714,0.000049855367,0.00020179323,0.00038196504,0.0001862579,0.000006905241,0.00000782806,0.00021490622,0.00021125631,0.9966713,0.00063142355],"about_ca_topic_score_codex":0.0000064101946,"about_ca_topic_score_gemma":0.000003767737,"teacher_disagreement_score":0.94765484,"about_ca_system_score_codex":0.000048628495,"about_ca_system_score_gemma":0.000120692384,"threshold_uncertainty_score":0.99947995},"labels":[],"label_agreement":null},{"id":"W1894734502","doi":"10.1002/gps.4250","title":"The longitudinal associations between C‐reactive protein and depressive symptoms: evidence from the English Longitudinal Study of Ageing (ELSA)","year":2014,"lang":"en","type":"article","venue":"International Journal of Geriatric Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; University College London","keywords":"Depression (economics); Longitudinal study; Ageing; C-reactive protein; Depressive symptoms; Late life depression; Internal medicine; Logistic regression; Medicine; Prospective cohort study; Geriatric Depression Scale; Center for Epidemiologic Studies Depression Scale; Psychology; Psychiatry; Cognition; Pathology; Inflammation","score_opus":0.030794080693301317,"score_gpt":0.3012903106696179,"score_spread":0.2704962299763166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1894734502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942763,0.0006290862,0.00089564186,0.001703044,0.0020042197,0.000306129,0.000038311908,0.000013137747,0.00013415195],"genre_scores_gemma":[0.9977942,0.00006107386,0.0001119987,0.000071995375,0.0019193813,0.000009783919,9.939547e-7,0.000013777275,0.000016810493],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99732,0.000489883,0.0006978019,0.00028052667,0.0010154671,0.00019632783],"domain_scores_gemma":[0.9942844,0.0034794367,0.0014293127,0.00022733482,0.000503919,0.000075580494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007311955,0.00016988354,0.00026336196,0.00012776745,0.00033751302,0.00022724218,0.001136624,0.0000609424,0.000012662128],"category_scores_gemma":[0.0038681356,0.000105712796,0.00014403668,0.00027868123,0.00015209416,0.00049005775,0.00017737153,0.0004408961,0.000001963213],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019122915,0.00028657855,0.989589,0.0000033791985,0.00034412122,0.0000102054255,0.0023522335,0.000045216202,0.0015019778,0.00079982297,0.00037913705,0.004497108],"study_design_scores_gemma":[0.0012943101,0.000347429,0.99078476,0.00012992129,0.00009737969,0.0000127100575,0.0008830785,0.000031458807,0.0007812289,0.005417706,0.00010114742,0.000118853466],"about_ca_topic_score_codex":0.00020805988,"about_ca_topic_score_gemma":0.0001653193,"teacher_disagreement_score":0.004617883,"about_ca_system_score_codex":0.000065627755,"about_ca_system_score_gemma":0.00014496114,"threshold_uncertainty_score":0.4630799},"labels":[],"label_agreement":null},{"id":"W1897872731","doi":"10.3109/15622975.2015.1073856","title":"Valproate augmentation in a subgroup of patients with treatment-resistant unipolar depression","year":2015,"lang":"en","type":"article","venue":"The World Journal of Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Concordia University; McGill University Health Centre; McGill University","funders":"","keywords":"Antidepressant; Internal medicine; Depression (economics); Medicine; Rating scale; Regimen; Clinical trial; Clinical Global Impression; Observational study; Treatment-resistant depression; Psychology","score_opus":0.040516338086313636,"score_gpt":0.27828482268785637,"score_spread":0.23776848460154273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1897872731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99809533,0.00040534977,0.000029856054,0.00059051154,0.00024038987,0.000163237,0.0000062059744,0.000006444893,0.00046264913],"genre_scores_gemma":[0.9992952,0.000042983764,0.00032855713,0.00024190378,0.000038510287,0.000001954564,0.0000013475235,0.000005520485,0.000044018387],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99887794,0.00028118587,0.00034119573,0.00012626138,0.00022629317,0.00014709847],"domain_scores_gemma":[0.9992697,0.000118843105,0.0003769233,0.000121034805,0.00004011201,0.0000733564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023501515,0.000107900894,0.00018937152,0.00012018691,0.00004307866,0.00001126671,0.00022924891,0.000032532527,0.000023239283],"category_scores_gemma":[0.000075946344,0.00004625498,0.00006621636,0.00037124555,0.00013912517,0.00008866116,0.000022678614,0.00013089107,0.0000028125119],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0073965597,0.0016729848,0.96742594,0.000008882549,0.000021444046,0.000008254157,0.0004690454,0.00015690613,0.01623031,0.0009724128,0.0003686027,0.005268654],"study_design_scores_gemma":[0.007339154,0.0028333752,0.9723009,0.00010270482,0.0000162646,0.000007274347,0.0004656852,0.000016464655,0.009369794,0.0065252185,0.0008820871,0.00014108386],"about_ca_topic_score_codex":0.000010221738,"about_ca_topic_score_gemma":0.00008862137,"teacher_disagreement_score":0.0068605156,"about_ca_system_score_codex":0.00004448267,"about_ca_system_score_gemma":0.00005817513,"threshold_uncertainty_score":0.18862233},"labels":[],"label_agreement":null},{"id":"W1917038036","doi":"10.1002/jms.3313","title":"Simultaneous detection of stable isotope‐labeled and unlabeled <scp>l</scp>‐tryptophan and of its main metabolites, <scp>l</scp>‐kynurenine, serotonin and quinolinic acid, by gas chromatography/negative ion chemical ionization mass spectrometry","year":2014,"lang":"en","type":"article","venue":"Journal of Mass Spectrometry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"","keywords":"Chemistry; Quinolinic acid; Tryptophan; Kynurenine; Chromatography; Chemical ionization; Kynurenine pathway; Mass spectrometry; Ion; Biochemistry; Ionization; Amino acid; Organic chemistry","score_opus":0.0069706500854636,"score_gpt":0.22134277556048843,"score_spread":0.21437212547502482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1917038036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9878857,0.00604138,0.00479596,0.00007100444,0.0002035084,0.00057000347,0.00008545083,0.00005922647,0.0002877544],"genre_scores_gemma":[0.9887648,0.0039535165,0.0068050087,0.00008824798,0.00015918484,0.000008635809,0.0000061637857,0.0000724432,0.00014198493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9958305,0.00050447887,0.0012816424,0.0007140917,0.00094776985,0.00072153064],"domain_scores_gemma":[0.9943545,0.002961302,0.0016474924,0.00033040438,0.0003128735,0.00039346822],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009381305,0.000549197,0.0012266976,0.0013648013,0.00017790974,0.00013302662,0.00038240885,0.00036369936,0.000030174346],"category_scores_gemma":[0.007760341,0.0005082746,0.00023327481,0.0025487472,0.00046651202,0.0006200599,0.00012267586,0.0007691463,0.0000022596676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010987648,0.0002776204,0.0021700254,0.0003069354,0.0001484118,0.000018690138,0.0003030547,0.000016159602,0.9954066,0.0005641505,0.00014243211,0.000536031],"study_design_scores_gemma":[0.0040540565,0.0015093188,0.0033911492,0.0001491726,0.0001504363,0.00030031116,0.0007060486,0.0021268711,0.98439574,0.00278422,0.00027036673,0.00016233073],"about_ca_topic_score_codex":0.000010849826,"about_ca_topic_score_gemma":0.0000049391674,"teacher_disagreement_score":0.011010895,"about_ca_system_score_codex":0.00009892908,"about_ca_system_score_gemma":0.00008806704,"threshold_uncertainty_score":0.9997369},"labels":[],"label_agreement":null},{"id":"W192397240","doi":"10.1186/cc14535","title":"Cannabinoid 2 receptor antagonism reverses central nervous system injury-induced immune deficiency syndrome","year":2015,"lang":"en","type":"article","venue":"Critical Care","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Immune system; Central nervous system; Cannabinoid; Immunology; Antagonism; Stroke (engine); Receptor; Cannabinoid receptor type 2; Cannabinoid receptor; Internal medicine","score_opus":0.03848114785252266,"score_gpt":0.28953262024358184,"score_spread":0.2510514723910592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W192397240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98678255,0.0005931675,0.000044949804,0.0010438432,0.0028753167,0.00035215516,0.00018092479,0.0003931745,0.007733931],"genre_scores_gemma":[0.9990547,0.0000041022176,0.000076961966,0.00051519694,0.00010933361,0.000030720294,0.000012238244,0.00003775078,0.00015901127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974726,0.00021426243,0.0003332731,0.0006014427,0.0005285206,0.00084988796],"domain_scores_gemma":[0.99871176,0.00010719456,0.000040879455,0.0004476859,0.00017241528,0.00052007136],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001046286,0.00025429003,0.0003044497,0.00009001843,0.00025658178,0.00013821122,0.00047522146,0.00016106316,0.00006830431],"category_scores_gemma":[0.0020156424,0.00023703092,0.00013128812,0.0003847632,0.0002955819,0.00025236985,0.00014244931,0.0002955117,0.00038271316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023718717,0.00037131496,0.00040882075,0.0015670886,0.0000067126407,0.0013320623,0.0057684607,0.000012275802,0.8712726,0.10465364,0.00841716,0.0059526674],"study_design_scores_gemma":[0.0018224638,0.0016925989,0.0043883217,0.00026268832,0.000059293583,0.0008717549,0.050934523,0.000105440195,0.9269537,0.00060383655,0.010803194,0.0015022333],"about_ca_topic_score_codex":0.00013600069,"about_ca_topic_score_gemma":0.0000046767004,"teacher_disagreement_score":0.10404981,"about_ca_system_score_codex":0.00030438873,"about_ca_system_score_gemma":0.0002593386,"threshold_uncertainty_score":0.9665841},"labels":[],"label_agreement":null},{"id":"W1926247945","doi":"10.1034/j.1600-0404.2000.00011.x","title":"Book review","year":2000,"lang":"en","type":"article","venue":"Acta Neurologica Scandinavica","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Effector; CD8; Immunology; Cytotoxic T cell; Biology; Lymphocyte; Myelin; T lymphocyte; Molecular biology; Cell biology; Immune system; In vitro; Endocrinology; Central nervous system; Genetics","score_opus":0.02057387456544774,"score_gpt":0.26274881070788053,"score_spread":0.2421749361424328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1926247945","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.27411532,0.12388889,0.000004117748,0.13512522,0.00045963767,0.0019115857,0.00004369763,0.001562055,0.46288946],"genre_scores_gemma":[0.4576436,0.09022127,0.000009333034,0.4396135,0.00005024499,0.000041521973,0.0000026519517,0.000019603962,0.012398279],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99826896,0.00019997345,0.00023106004,0.00059861015,0.0002534373,0.00044795766],"domain_scores_gemma":[0.99911547,0.00020795714,0.00006166881,0.00046436227,0.000008986623,0.00014156273],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000080357386,0.00020445722,0.0002470518,0.00003791137,0.00019373538,0.00003919314,0.00055503217,0.00007399876,0.049821045],"category_scores_gemma":[0.0002772277,0.00015650876,0.00012287614,0.00036330931,0.00017944354,0.0001912141,0.000056865898,0.00025905002,0.0015007915],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007012856,0.00012433057,0.000052015967,0.000057429294,0.0000018225696,0.00011893711,0.000014853544,0.0000011803357,0.01802677,0.00011651819,0.9671811,0.014234947],"study_design_scores_gemma":[0.0002637438,0.00024132131,0.0023875611,0.000052014442,0.000007666071,0.00010247554,6.1804025e-7,0.000013944245,0.0033284517,0.00017374435,0.9932407,0.00018775866],"about_ca_topic_score_codex":0.000002808691,"about_ca_topic_score_gemma":3.6713283e-7,"teacher_disagreement_score":0.4504912,"about_ca_system_score_codex":0.00000911421,"about_ca_system_score_gemma":0.000015844653,"threshold_uncertainty_score":0.99927664},"labels":[],"label_agreement":null},{"id":"W1937564299","doi":"10.1007/s00213-015-4079-7","title":"Haloperidol and Risperidone at high concentrations activate an in vitro inflammatory response of RAW 264.7 macrophage cells by induction of apoptosis and modification of cytokine levels","year":2015,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Haloperidol; Pharmacology; Antipsychotic; Cytokine; Risperidone; Apoptosis; Psychosis; Medicine; Endocrinology; Internal medicine; Chemistry; Dopamine; Schizophrenia (object-oriented programming); Psychiatry; Biochemistry","score_opus":0.039449953526225226,"score_gpt":0.30991507338899904,"score_spread":0.27046511986277383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1937564299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987106,0.00010538777,0.000068006586,0.00027443597,0.0002772624,0.0003777586,0.00014094185,0.000014245506,0.00003137135],"genre_scores_gemma":[0.99942064,0.00019761197,0.00014714868,0.00012634542,0.000016834496,0.000028118082,0.000006421909,0.000013796783,0.000043107364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984494,0.0005135745,0.00039854806,0.00032478673,0.00014395545,0.00016975675],"domain_scores_gemma":[0.9991821,0.0001970291,0.0002833692,0.00016440325,0.000062797866,0.000110267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030982046,0.00012854527,0.00025876664,0.00017110133,0.0000395415,0.0000057336374,0.00012154643,0.00010685426,0.00004207391],"category_scores_gemma":[0.00011108463,0.00013278953,0.000020299003,0.00026463074,0.00049120386,0.0002221376,0.000043932723,0.00011433011,0.000001504525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0067236386,0.00024802575,0.00023545683,0.00003368635,0.000007510723,0.0000010113132,0.0011834647,0.000086147746,0.9904222,0.00003364363,0.0002563811,0.0007688502],"study_design_scores_gemma":[0.004307763,0.0002109819,0.006391894,0.000005923498,0.000009648484,0.000004054132,0.00017502501,0.00029226096,0.98828894,0.00006085547,0.00015057184,0.00010206706],"about_ca_topic_score_codex":0.000036588455,"about_ca_topic_score_gemma":0.000002942385,"teacher_disagreement_score":0.006156437,"about_ca_system_score_codex":0.000043374865,"about_ca_system_score_gemma":0.000050729934,"threshold_uncertainty_score":0.5415},"labels":[],"label_agreement":null},{"id":"W1945545951","doi":"10.1016/j.schres.2015.05.010","title":"Using a maternal immune stimulation model of schizophrenia to study behavioral and neurobiological alterations over the developmental course","year":2015,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research; Ministerio de Ciencia e Innovación; Canadian HIV Trials Network, Canadian Institutes of Health Research; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft; European Commission","keywords":"Neurochemical; Prefrontal cortex; Neuroscience; Psychology; Nucleus accumbens; Hippocampus; Globus pallidus; Amygdala; Schizophrenia (object-oriented programming); Stimulation; Dopamine; Basal ganglia; Central nervous system; Psychiatry","score_opus":0.2639351589970123,"score_gpt":0.4250536263789889,"score_spread":0.1611184673819766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1945545951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99845666,0.0000303977,0.00020329682,0.00016498404,0.00008807966,0.0009348282,0.000031968397,0.000032515574,0.00005728468],"genre_scores_gemma":[0.99670565,0.0000021928965,0.00307405,0.000045874698,0.00003985402,0.00004215405,0.0000023935877,0.000019440355,0.00006837996],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9975037,0.00056157017,0.0003253918,0.0004456105,0.00076802884,0.0003957033],"domain_scores_gemma":[0.9991587,0.00016940093,0.000057470927,0.00027373023,0.00014740838,0.00019333401],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008668328,0.00015898468,0.00018245842,0.00019671884,0.0004471277,0.00016770851,0.00043465695,0.00005774791,0.00003596422],"category_scores_gemma":[0.00032854584,0.000112259666,0.00003679091,0.00057834294,0.00032571043,0.00020332322,0.00051875453,0.00037810268,0.00002203813],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003329714,0.0012366915,0.0138215795,0.000008002405,0.000015066583,0.000027171602,0.0028419667,0.008743075,0.96374893,0.0018225217,0.00014065352,0.004264635],"study_design_scores_gemma":[0.013454549,0.0025332528,0.58829826,0.000066456596,0.00004550259,0.000114649454,0.0028821842,0.23129132,0.1527179,0.0077869557,0.000030759293,0.0007782097],"about_ca_topic_score_codex":0.00013269123,"about_ca_topic_score_gemma":0.000059001002,"teacher_disagreement_score":0.81103104,"about_ca_system_score_codex":0.000057895497,"about_ca_system_score_gemma":0.00030938096,"threshold_uncertainty_score":0.45778164},"labels":[],"label_agreement":null},{"id":"W1964827701","doi":"10.1111/j.1399-5618.2005.00239.x","title":"Reductions in cholesterol and synaptic markers in association cortex in mood disorders","year":2005,"lang":"en","type":"article","venue":"Bipolar Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Desmosterol; Lathosterol; Internal medicine; Cholesterol; Endocrinology; Major depressive disorder; Bipolar disorder; Mood disorders; Schizophrenia (object-oriented programming); Synaptophysin; Myelin; Psychology; Neuroscience; Medicine; Central nervous system; Psychiatry; Sterol; Lithium (medication); Amygdala","score_opus":0.007901616790900484,"score_gpt":0.23095675281450304,"score_spread":0.22305513602360255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964827701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992174,0.0010358448,0.000015026697,0.0042158584,0.00014483872,0.00055468106,0.000010476318,0.000063929365,0.0017852996],"genre_scores_gemma":[0.9943085,0.0049931547,0.000060413553,0.00033133116,0.000018265178,0.00007117234,0.0000047780786,0.00003154832,0.0001808515],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99789184,0.0002558247,0.0004146169,0.00059542386,0.00026699642,0.00057529693],"domain_scores_gemma":[0.99934083,0.00023587365,0.00011860135,0.00021701319,0.000007143719,0.00008054621],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034213954,0.000228472,0.00023924909,0.00062668923,0.00008189559,0.000059650432,0.00021563965,0.00017429881,0.000052517706],"category_scores_gemma":[0.00068733207,0.00026232214,0.000057218185,0.0010655907,0.00012988798,0.00050057785,0.00006131805,0.00041332236,0.000036686928],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000096772215,0.0009419142,0.82630706,0.00004005066,0.000012461309,0.0000021098078,0.0019258698,0.0010861472,0.013591647,0.00059396797,0.00015637619,0.15524562],"study_design_scores_gemma":[0.002792238,0.00006502906,0.9827099,0.000044333276,0.0000049342802,0.0000027021,0.0009978149,0.002576776,0.00028587406,0.0011470922,0.009024505,0.000348791],"about_ca_topic_score_codex":0.000750125,"about_ca_topic_score_gemma":0.07281951,"teacher_disagreement_score":0.15640284,"about_ca_system_score_codex":0.0002872292,"about_ca_system_score_gemma":0.0000502256,"threshold_uncertainty_score":0.9999829},"labels":[],"label_agreement":null},{"id":"W1965350402","doi":"10.1371/journal.ppat.0040028","title":"Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis","year":2008,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":158,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Center for AIDS Research, University of Washington; York University; National Institutes of Health; Parkinson's Disease Foundation","keywords":"Phagocytosis; Antigen processing; Antigen presentation; Antigen; Presentation (obstetrics); Cell biology; Immunology; Chemistry; Biology; Medicine; Immune system; T cell","score_opus":0.058836939576348696,"score_gpt":0.2668575641180425,"score_spread":0.20802062454169382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965350402","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956314,0.0006230277,0.00014657431,0.00018734818,0.000035494184,0.00022567899,0.000034145025,0.00013989229,0.0029764648],"genre_scores_gemma":[0.9976699,0.0004835552,0.0006691674,0.00055937516,0.000056685323,0.000024726154,0.000004757078,0.000023912742,0.00050791935],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988173,0.00007699958,0.00016864669,0.00040513373,0.00027772615,0.0002541789],"domain_scores_gemma":[0.9995464,0.00007828528,0.000072275485,0.00015549055,0.000041573167,0.00010593708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004810263,0.00014273936,0.00014819969,0.000089802925,0.00027967204,0.000032895594,0.00012159873,0.000050611045,0.00008038085],"category_scores_gemma":[0.00035890072,0.00012915638,0.00003777362,0.00033312716,0.00019666278,0.00020530132,0.000059162114,0.00007938241,0.00007089412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011415169,0.00016120472,0.0116201965,0.000026451882,0.000004976647,0.000042140528,0.0011761168,0.000002036232,0.9792836,0.00006238821,0.00025836704,0.0073511507],"study_design_scores_gemma":[0.0004547968,0.000045019926,0.01506647,0.000014434557,0.000009447928,0.000069549584,0.00008162579,0.0004543949,0.98118633,0.00019861564,0.002236225,0.00018307073],"about_ca_topic_score_codex":0.0000037532816,"about_ca_topic_score_gemma":0.0000025905547,"teacher_disagreement_score":0.00716808,"about_ca_system_score_codex":0.000009396553,"about_ca_system_score_gemma":0.000042522388,"threshold_uncertainty_score":0.52668446},"labels":[],"label_agreement":null},{"id":"W1965456396","doi":"10.1016/j.pnpbp.2014.11.002","title":"Behavioral alterations in rat offspring following maternal immune activation and ELR-CXC chemokine receptor antagonism during pregnancy: Implications for neurodevelopmental psychiatric disorders","year":2014,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; University of Saskatchewan","keywords":"CXCL1; Offspring; Prepulse inhibition; Chemokine; CXC chemokine receptors; Pregnancy; Psychology; Internal medicine; Medicine; Endocrinology; Immunology; Receptor; Schizophrenia (object-oriented programming); Chemokine receptor; Biology; Psychiatry","score_opus":0.021173788283140073,"score_gpt":0.3145751617679179,"score_spread":0.2934013734847778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965456396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99074334,0.0006204089,0.000089844216,0.0053662565,0.0018407404,0.0011736386,0.000016844526,0.00010084956,0.00004809161],"genre_scores_gemma":[0.99664634,0.000716426,0.0011493784,0.0007266904,0.000109561515,0.0005955577,0.00001772781,0.000027517284,0.000010813281],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976923,0.0002186287,0.0005472591,0.00092303386,0.000088060995,0.00053070264],"domain_scores_gemma":[0.99933404,0.00021198392,0.00017766717,0.00015959851,0.000011915117,0.0001047985],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014538091,0.00031251682,0.00031057346,0.00027699996,0.0004022733,0.000069446025,0.00027212503,0.00019633613,0.00001401746],"category_scores_gemma":[0.000067707195,0.00028130153,0.000090247915,0.00042911354,0.0002567813,0.00024913758,0.00011790233,0.0004149963,0.0000017230948],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054326653,0.0006025823,0.854191,0.00005769217,0.000005741389,0.0000014518346,0.00008248376,0.000004590698,0.12470829,0.00071464945,0.000019779227,0.019068476],"study_design_scores_gemma":[0.0055766185,0.00030976065,0.9848274,0.000052055137,0.000010643169,0.000019278848,0.00002740717,0.00012321127,0.006083183,0.0024155485,0.00022122044,0.0003336599],"about_ca_topic_score_codex":0.000003785512,"about_ca_topic_score_gemma":0.000013038721,"teacher_disagreement_score":0.13063641,"about_ca_system_score_codex":0.00002378708,"about_ca_system_score_gemma":0.00002583118,"threshold_uncertainty_score":0.99996394},"labels":[],"label_agreement":null},{"id":"W1967904504","doi":"10.1016/s0924-977x(00)80027-9","title":"The use of novel antipsychotics to improve response in schizophrenia: a naturalistic study in poor responders","year":2000,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"NFAT; Calcineurin; T-cell receptor; T cell; Cell biology; Biology; Humanities; Immunology; Medicine; Immune system; Internal medicine; Transplantation; Philosophy","score_opus":0.05322608157481883,"score_gpt":0.32391125626270123,"score_spread":0.2706851746878824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967904504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99484724,0.000030018848,0.000008481663,0.0020491371,0.0010716768,0.001412216,0.000025122723,0.00010653183,0.00044959912],"genre_scores_gemma":[0.9925158,0.000098706965,0.00013149079,0.006202481,0.00005464873,0.000025390253,4.1453285e-7,0.000107264765,0.00086379214],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99311835,0.0041060615,0.0008216584,0.00094114285,0.00033157924,0.0006812181],"domain_scores_gemma":[0.9966078,0.0024297608,0.00014639294,0.0006161616,0.000037533035,0.00016239748],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010159038,0.0003228715,0.0003258398,0.0005301945,0.00012315744,0.00008652929,0.0009977507,0.000050449857,0.00007471628],"category_scores_gemma":[0.0019916424,0.0002668247,0.00008464196,0.0018071627,0.00030503605,0.00017599657,0.00014018675,0.00073475763,0.00012822392],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06919612,0.0012752382,0.00017022269,0.000005810916,0.000007253545,0.00076497445,0.000794302,0.0019249796,0.9153918,0.000041772484,0.0019031992,0.008524318],"study_design_scores_gemma":[0.029241536,0.0038644534,0.8994311,0.000048257396,0.00002248916,0.00008167411,0.00025427065,0.0019490687,0.005747105,0.000036384674,0.058534082,0.0007895756],"about_ca_topic_score_codex":0.000015488118,"about_ca_topic_score_gemma":0.000052971485,"teacher_disagreement_score":0.9096447,"about_ca_system_score_codex":0.00004435768,"about_ca_system_score_gemma":0.000059858317,"threshold_uncertainty_score":0.9999784},"labels":[],"label_agreement":null},{"id":"W1968545758","doi":"10.1038/sj.mp.4002110","title":"Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression","year":2007,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":293,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Prefrontal cortex; Neuroscience; GABAergic; Biology; Serotonergic; Psychology; Psychiatry; Genetics; Serotonin; Cognition; Inhibitory postsynaptic potential","score_opus":0.011276435963989462,"score_gpt":0.24540012740869327,"score_spread":0.2341236914447038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968545758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973407,0.0016552517,0.0003945206,0.00012186537,0.000052201027,0.00035026605,0.00000400536,0.000009807256,0.00007141994],"genre_scores_gemma":[0.9986725,0.00007975561,0.0010375585,0.00017595646,0.000008025196,0.0000063402554,0.0000010246921,0.000016761038,0.0000020761254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987876,0.0001508913,0.00027384734,0.00033307268,0.00024060918,0.00021399723],"domain_scores_gemma":[0.99954253,0.00006771648,0.000118999,0.00021026644,0.000008231898,0.000052281164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001805598,0.00014921771,0.00019058828,0.00014488924,0.000039411727,0.000011994765,0.00016704395,0.00006135043,0.000004185039],"category_scores_gemma":[0.000031314907,0.00009734134,0.00003445228,0.00022920688,0.00017540206,0.00007840845,0.000037470174,0.00012025884,1.2213411e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045874616,0.00015356783,0.22537868,0.000081057,0.0000015328601,0.000010165212,0.0004823657,0.0000084649955,0.7725149,0.00003062043,0.000001988206,0.0008779403],"study_design_scores_gemma":[0.00094759226,0.000105724546,0.45886028,0.00021014718,0.0000056139193,0.0000133134245,0.00030885864,0.00006331934,0.53926504,0.00014041491,0.0000047543663,0.00007497852],"about_ca_topic_score_codex":0.00007222396,"about_ca_topic_score_gemma":0.0002441743,"teacher_disagreement_score":0.23348159,"about_ca_system_score_codex":0.0000046169594,"about_ca_system_score_gemma":0.000025773243,"threshold_uncertainty_score":0.3969465},"labels":[],"label_agreement":null},{"id":"W1968731032","doi":"10.1016/j.bbi.2014.06.201","title":"Greater amygdala activity and dorsomedial prefrontal–amygdala coupling are associated with enhanced inflammatory responses to stress","year":2014,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":238,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"National Center for Advancing Translational Sciences; National Institute of Mental Health; National Institute on Aging; Canadian Institutes of Health Research","keywords":"Amygdala; Stressor; Prefrontal cortex; Psychology; Neurocognitive; Social stress; Inflammation; Neuroscience; Feeling; Medicine; Clinical psychology; Internal medicine; Cognition","score_opus":0.020187144990504113,"score_gpt":0.2551477073640189,"score_spread":0.23496056237351481,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968731032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99875927,0.000011249569,0.00006241153,0.00023233841,0.00010643745,0.0004957303,0.000080048994,0.0001307121,0.00012182932],"genre_scores_gemma":[0.99897444,0.000008868934,0.000024351864,0.0003105349,0.00003225531,0.000087693414,0.0000071017384,0.000033463235,0.0005212907],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99831194,0.0003628233,0.00018160594,0.00046996155,0.00027369658,0.000399995],"domain_scores_gemma":[0.9986483,0.0005972901,0.00013724553,0.00035680976,0.000047166723,0.00021322974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003547863,0.00027907547,0.00030251525,0.00013758335,0.00045668523,0.00014236159,0.00021475034,0.0001407229,0.00002458518],"category_scores_gemma":[0.0011977014,0.00023869018,0.000038848983,0.00020017622,0.00035837368,0.00029658267,0.00019172943,0.00034626242,0.0000053474546],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000645231,0.0002497346,0.10431069,0.000026583853,0.000007906558,0.000015692036,0.0019171741,0.000004856807,0.888469,0.000017485861,0.00004750601,0.004288166],"study_design_scores_gemma":[0.0010762226,0.0002611948,0.7573018,0.0000821779,0.000016344853,0.0000063799203,0.0003263119,0.000033341068,0.24055566,0.000010518411,0.00006303282,0.00026698696],"about_ca_topic_score_codex":0.00006689851,"about_ca_topic_score_gemma":0.00033541708,"teacher_disagreement_score":0.6529911,"about_ca_system_score_codex":0.000042374388,"about_ca_system_score_gemma":0.000037296817,"threshold_uncertainty_score":0.9733503},"labels":[],"label_agreement":null},{"id":"W1968978082","doi":"10.1016/j.jagp.2014.05.008","title":"Oxidative Stress in Older Patients with Bipolar Disorder","year":2014,"lang":"en","type":"article","venue":"American Journal of Geriatric Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Center for Advancing Translational Sciences; National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Oxidative stress; Bipolar disorder; Psychology; Clinical psychology; Medicine; Psychiatry; Internal medicine; Cognition","score_opus":0.003850254433077914,"score_gpt":0.2177457330391718,"score_spread":0.2138954786060939,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968978082","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99677813,0.00021652272,0.0012961434,0.0005925211,0.00060078636,0.00014139332,0.000010424894,0.000015350844,0.00034871558],"genre_scores_gemma":[0.9973124,0.000059571514,0.0016305434,0.00076616806,0.0001764761,0.0000027707097,0.0000011289438,0.000029838753,0.000021068801],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981878,0.00028397914,0.00045924686,0.00027718703,0.00044705547,0.00034477748],"domain_scores_gemma":[0.998608,0.00018036901,0.00076649245,0.00022319057,0.0000739931,0.00014798375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017183466,0.00020591464,0.00037297158,0.00041786692,0.000072889496,0.000037372625,0.0004192537,0.000034498564,0.000059121146],"category_scores_gemma":[0.00017521137,0.00015076259,0.00009931627,0.0012906732,0.00024031015,0.00027433547,0.000033959426,0.00033180113,0.000012903462],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035507465,0.0011072528,0.94721884,0.000016172418,0.000017173474,0.0000036981196,0.0004302287,0.00011299751,0.00047327322,0.00032442645,0.0004449599,0.04949593],"study_design_scores_gemma":[0.0047480543,0.0024569386,0.986288,0.000092133894,0.000023768343,0.00001765096,0.001057596,0.000035115303,0.0006730655,0.00051628286,0.0036835293,0.00040782828],"about_ca_topic_score_codex":0.00003559517,"about_ca_topic_score_gemma":0.00003915261,"teacher_disagreement_score":0.0490881,"about_ca_system_score_codex":0.000030308376,"about_ca_system_score_gemma":0.00012531168,"threshold_uncertainty_score":0.614792},"labels":[],"label_agreement":null},{"id":"W1970234726","doi":"10.1016/j.jad.2009.04.007","title":"Altered expression of lipid metabolism and immune response genes in the frontal cortex of suicide completers","year":2009,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Lipid metabolism; Microarray analysis techniques; Microarray; Internal medicine; Endocrinology; Biology; Major depressive disorder; Gene; Gene expression; Psychology; Medicine; Genetics","score_opus":0.016481295509935993,"score_gpt":0.27290035743030133,"score_spread":0.25641906192036534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970234726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99718666,0.0014888266,0.00018293456,0.00056130474,0.00014611115,0.00023496909,0.000009304315,0.0000037510583,0.00018612096],"genre_scores_gemma":[0.9992356,0.00037648773,0.000115985385,0.00023028851,0.000027001384,0.0000016156204,3.7958935e-7,0.000008360072,0.0000043198306],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980713,0.0007961198,0.00045470017,0.00015736425,0.00034027593,0.00018023344],"domain_scores_gemma":[0.9983052,0.00091580645,0.00052910455,0.00015814097,0.00004971833,0.00004205169],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063997495,0.00014661324,0.0003914672,0.00026932088,0.000056089888,0.000015496547,0.00031741973,0.000047678437,0.000012870629],"category_scores_gemma":[0.00072997593,0.00009821897,0.00015940376,0.0002986196,0.00025060645,0.00022450263,0.00003064706,0.00021428395,3.466609e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002340575,0.00028849897,0.0011237875,0.0000107913465,0.000007952172,0.00000517721,0.0024551004,0.000059715796,0.9836105,0.00011146295,0.000079383484,0.009907043],"study_design_scores_gemma":[0.0021840935,0.00074692,0.6900164,0.000075166674,0.000011875267,0.000029123397,0.0025770743,0.000039996758,0.30305928,0.001052935,0.00011491274,0.000092240996],"about_ca_topic_score_codex":0.000043221695,"about_ca_topic_score_gemma":0.000030331665,"teacher_disagreement_score":0.6888926,"about_ca_system_score_codex":0.0000157012,"about_ca_system_score_gemma":0.000043865286,"threshold_uncertainty_score":0.4005253},"labels":[],"label_agreement":null},{"id":"W1970461644","doi":"10.1007/s00213-006-0482-4","title":"Family and case–control association study of the tumor necrosis factor-alpha (TNF-α) gene with schizophrenia and response to antipsychotic medication","year":2006,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia (object-oriented programming); Antipsychotic; Tumor necrosis factor alpha; Association (psychology); Tumor necrosis factor α; Psychosis; Medicine; Psychology; Psychiatry; Internal medicine; Pharmacology; Clinical psychology; Oncology; Psychotherapist","score_opus":0.011885536813892855,"score_gpt":0.27484573231003906,"score_spread":0.2629601954961462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970461644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973696,0.00007116139,0.000067663095,0.0010221316,0.0002848233,0.00094874145,0.000035365632,0.000039386843,0.0001611239],"genre_scores_gemma":[0.99797183,0.0000114596105,0.00007428191,0.0015290302,0.00004128145,0.00005793808,1.9115399e-7,0.000023277811,0.00029071857],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983614,0.00055768533,0.00023142714,0.0004057722,0.0002225426,0.00022114563],"domain_scores_gemma":[0.9989335,0.00057031127,0.00020591769,0.00017874906,0.000032402688,0.000079108715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025730996,0.00014491938,0.00019328612,0.00013357945,0.00015675172,0.000025092466,0.0001442683,0.000050542363,0.00003649226],"category_scores_gemma":[0.00016100012,0.000104911334,0.00002128646,0.0003603809,0.00010014253,0.000061198094,0.000029398174,0.00012212594,0.000005881789],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003829911,0.00042426327,0.033236332,0.000007710561,0.000026188845,0.000044728487,0.00049548614,0.000015007993,0.95971197,0.000017212944,0.00084852485,0.0013426766],"study_design_scores_gemma":[0.011896327,0.00062600116,0.96746075,0.0000075674207,0.00006213254,0.000102990816,0.00015181255,0.000089515226,0.019059759,0.00007438499,0.0003150657,0.00015371713],"about_ca_topic_score_codex":0.00011206409,"about_ca_topic_score_gemma":0.00017048634,"teacher_disagreement_score":0.9406522,"about_ca_system_score_codex":0.000046737074,"about_ca_system_score_gemma":0.00005027499,"threshold_uncertainty_score":0.427816},"labels":[],"label_agreement":null},{"id":"W1970565358","doi":"10.1371/journal.pone.0029754","title":"Early Alterations in Hippocampal Circuitry and Theta Rhythm Generation in a Mouse Model of Prenatal Infection: Implications for Schizophrenia","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Hippocampal formation; Neuroscience; Hippocampus; Schizophrenia (object-oriented programming); Offspring; Inhibitory postsynaptic potential; Parvalbumin; Excitatory postsynaptic potential; Neurotransmission; Biology; Psychology; Medicine; Pregnancy; Internal medicine; Psychiatry","score_opus":0.09243707057912488,"score_gpt":0.26727130732725735,"score_spread":0.17483423674813248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970565358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973052,0.00004646413,0.0016853609,0.00022027563,0.000014457821,0.00049429835,0.00008833153,0.000022048613,0.00012354126],"genre_scores_gemma":[0.99839205,0.0000369496,0.0011034508,0.000071651055,0.00005886586,0.00023126283,0.000012898648,0.000010941026,0.00008194992],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935853,0.000038128055,0.00018664968,0.00017195463,0.00008199546,0.00016271987],"domain_scores_gemma":[0.99966747,0.000064101165,0.00005224807,0.0001493462,0.000023144716,0.000043700988],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008354007,0.00007337455,0.00010909525,0.00013629468,0.000063939835,0.000024098827,0.000048087604,0.0000489946,0.000004231518],"category_scores_gemma":[0.00017085593,0.000077490135,0.000020696403,0.00017170764,0.000045973535,0.00039945258,0.000021747546,0.00008050942,0.000002067407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028028619,0.0009847604,0.010162188,0.00004212386,0.0000048468223,3.833721e-8,0.00086330104,0.0004560827,0.974942,0.011827165,0.0000065597715,0.0006828923],"study_design_scores_gemma":[0.0015019357,0.00007770966,0.052484807,0.000035327674,0.000012335201,0.0000026149066,0.000014345267,0.06710261,0.873606,0.0049847662,0.0000015739625,0.00017593692],"about_ca_topic_score_codex":0.000024806397,"about_ca_topic_score_gemma":0.00011765876,"teacher_disagreement_score":0.10133598,"about_ca_system_score_codex":0.000021086573,"about_ca_system_score_gemma":0.000030306654,"threshold_uncertainty_score":0.3159956},"labels":[],"label_agreement":null},{"id":"W1971861775","doi":"10.1139/cjpp-2014-0560","title":"Antidepressant-like effect of simvastatin in diabetic rats","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Endocrinology; Internal medicine; Streptozotocin; Clomipramine; Behavioural despair test; Corticosterone; Neurochemical; Antidepressant; Serotonin; Simvastatin; Dopamine; Diabetes mellitus; Medicine; Hippocampus; Hormone","score_opus":0.021959759329859035,"score_gpt":0.28627127026430726,"score_spread":0.2643115109344482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971861775","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980639,0.000514851,0.000002451437,0.00024160855,0.0008023308,0.0000909991,0.000009312728,0.000002059033,0.00027247414],"genre_scores_gemma":[0.9989878,0.000048356746,0.000010329354,0.00086384785,0.00006194702,0.0000020506511,5.355335e-7,0.000006486388,0.000018670815],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987082,0.0005927522,0.00024512268,0.00013285417,0.000050608618,0.0002705008],"domain_scores_gemma":[0.9989179,0.0004981069,0.0001570238,0.000052335712,0.000035872174,0.0003388106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029220534,0.00009835827,0.00031656618,0.00024864718,0.00003493907,0.000003819658,0.00017901535,0.000073849595,0.00022208168],"category_scores_gemma":[0.000195207,0.000081061284,0.000041061747,0.00016051196,0.00041110846,0.000081751925,0.000015047548,0.0002450597,0.0000048840916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020894558,0.00001806611,0.007250145,0.00004180072,0.000010161641,0.00014633514,0.00041110438,0.00019570775,0.988368,0.000053763306,0.0026151703,0.0006808357],"study_design_scores_gemma":[0.0022989616,0.0009192991,0.012717143,0.000014892852,0.000016229116,0.000065010754,0.000037653223,0.00008674063,0.98127216,0.0010913399,0.0013892506,0.00009131649],"about_ca_topic_score_codex":0.00018833455,"about_ca_topic_score_gemma":0.00041604848,"teacher_disagreement_score":0.0070958016,"about_ca_system_score_codex":0.000020190435,"about_ca_system_score_gemma":0.00034511054,"threshold_uncertainty_score":0.33055833},"labels":[],"label_agreement":null},{"id":"W1971900958","doi":"10.1152/ajprenal.00044.2007","title":"Proapoptotic activity of indoleamine 2,3-dioxygenase expressed in renal tubular epithelial cells","year":2007,"lang":"en","type":"article","venue":"American Journal of Physiology-Renal Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Fas ligand; Indoleamine 2,3-dioxygenase; TEC; Apoptosis; Immune system; Cancer research; Tumor necrosis factor alpha; Immunology; Biology; Programmed cell death; Medicine; Biochemistry; Tryptophan","score_opus":0.013189974514937182,"score_gpt":0.2564938522603643,"score_spread":0.24330387774542714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971900958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99899936,0.000033873985,0.0002533966,0.00009395252,0.00027119403,0.0002068914,0.00003242443,0.000019174586,0.00008971165],"genre_scores_gemma":[0.9986064,0.000070018745,0.00045752258,0.00046226574,0.00034396446,0.000004759054,0.0000024012545,0.00003388528,0.000018778694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966063,0.00075068674,0.0009602688,0.0005540744,0.00034451394,0.0007841644],"domain_scores_gemma":[0.99677926,0.0009714883,0.001496574,0.00040610356,0.00013365354,0.00021291758],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005647616,0.00037033402,0.0011847145,0.0005347553,0.00007052774,0.0000072710227,0.00076467573,0.000135118,0.00009006023],"category_scores_gemma":[0.00042278614,0.00030195512,0.00034340852,0.0008559004,0.0017180332,0.00023226494,0.00014993301,0.000797364,0.000019760462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035046323,0.00081818644,0.000014140178,0.000030822437,0.000040308933,0.000043181466,0.0002802009,0.0010922604,0.9876656,0.00009660159,0.00008017493,0.006333914],"study_design_scores_gemma":[0.0018394135,0.00243254,0.05059557,0.000051055595,0.000009220286,0.000039819137,0.00016896473,0.00007412687,0.94275486,0.0016055683,0.00016437423,0.00026448545],"about_ca_topic_score_codex":0.00007206455,"about_ca_topic_score_gemma":0.000011961847,"teacher_disagreement_score":0.05058143,"about_ca_system_score_codex":0.00006649659,"about_ca_system_score_gemma":0.00018534287,"threshold_uncertainty_score":0.99994326},"labels":[],"label_agreement":null},{"id":"W1973580143","doi":"10.1016/j.psym.2013.12.010","title":"Metabolic Syndrome and Elevated C-Reactive Protein Levels in Elderly Patients With Newly Diagnosed Depression","year":2013,"lang":"en","type":"article","venue":"Psychosomatics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Medicine; Depression (economics); Odds ratio; Waist; Internal medicine; C-reactive protein; Risk factor; Metabolic syndrome; Disease; Obesity; Inflammation","score_opus":0.015249181792765562,"score_gpt":0.24043880376891186,"score_spread":0.22518962197614628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973580143","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99773175,0.000041821688,0.00018081901,0.00013218043,0.00005544453,0.0014645397,0.000010495702,0.00006921052,0.00031375283],"genre_scores_gemma":[0.99819463,0.000005376833,0.0012246607,0.00025198542,0.0000062531158,0.00021471352,0.0000025451093,0.000028819184,0.00007099844],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99867654,0.0001030491,0.0002433736,0.00037293145,0.00029134672,0.00031274746],"domain_scores_gemma":[0.9993023,0.0001536893,0.00012942533,0.000266704,0.00003775314,0.00011009232],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000042111016,0.0001994301,0.0002310665,0.0001349905,0.00007093157,0.00008314254,0.0001817701,0.00007595962,0.000076756616],"category_scores_gemma":[0.00023565251,0.0001490717,0.000021181424,0.000407711,0.000089153975,0.00041790074,0.000034269728,0.00016474811,0.00007286324],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017881741,0.0032024963,0.538868,0.00024033716,0.000051886982,0.00007704062,0.0049619,0.000039129747,0.41076317,0.00085763185,0.00037906438,0.04038052],"study_design_scores_gemma":[0.0033255827,0.0001860776,0.96366996,0.00016857995,0.0000050766853,0.0000058163864,0.00010295736,0.0003075994,0.029788569,0.0021063115,0.00008131753,0.0002521441],"about_ca_topic_score_codex":0.000076489116,"about_ca_topic_score_gemma":0.000022678152,"teacher_disagreement_score":0.42480198,"about_ca_system_score_codex":0.000012700688,"about_ca_system_score_gemma":0.00001725953,"threshold_uncertainty_score":0.6078967},"labels":[],"label_agreement":null},{"id":"W1973929801","doi":"10.1016/j.neuropharm.2011.08.018","title":"Depressive-like behavior induced by tumor necrosis factor-α in mice","year":2011,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":289,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Behavioural despair test; Tail suspension test; Tumor necrosis factor alpha; Desipramine; Pharmacology; Open field; Imipramine; Fluoxetine; Endocrinology; Cytokine; Chemistry; Internal medicine; Antidepressant; Knockout mouse; Medicine; Receptor; Serotonin; Hippocampus; Pathology","score_opus":0.05739527932971778,"score_gpt":0.2982408830365219,"score_spread":0.24084560370680413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973929801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961523,0.000028659882,0.0000026266246,0.00009198444,0.0011610002,0.00044459364,0.000037249338,0.00013923139,0.001942354],"genre_scores_gemma":[0.9911053,0.00003385946,0.000018576337,0.008389892,0.000029969455,0.0001393519,0.0000013718155,0.000044852284,0.00023682439],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979347,0.0003554455,0.00029376041,0.00068323687,0.00016578255,0.00056709803],"domain_scores_gemma":[0.9992715,0.00023157259,0.00012119866,0.00019529412,0.000019431796,0.00016098654],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000039177576,0.00024177565,0.00023911775,0.00017199625,0.00009598733,0.00002111562,0.00057402696,0.00009860713,0.0014048758],"category_scores_gemma":[0.00016067212,0.00024494316,0.00006955236,0.00038429748,0.00015799914,0.00018941124,0.00016039722,0.0004601745,0.00026981364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000102362064,0.000492825,0.0042549283,0.000005821359,0.000001947798,0.00038354273,0.00032056423,3.171476e-7,0.9912705,0.000030768806,0.0017208345,0.0014155767],"study_design_scores_gemma":[0.0016433237,0.0001781286,0.08512666,0.0000024122978,0.000011170996,0.000032200987,0.000016331345,0.000021219264,0.9108183,0.000024811741,0.0018917437,0.00023371939],"about_ca_topic_score_codex":0.00012746475,"about_ca_topic_score_gemma":0.000017364373,"teacher_disagreement_score":0.08087174,"about_ca_system_score_codex":0.000031250358,"about_ca_system_score_gemma":0.000044927678,"threshold_uncertainty_score":0.99950796},"labels":[],"label_agreement":null},{"id":"W1973934110","doi":"10.1002/brb3.314","title":"Polymorphisms of <i>IKBKE</i> gene are associated with major depressive disorder and panic disorder","year":2015,"lang":"en","type":"article","venue":"Brain and Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"European Regional Development Fund","keywords":"Panic disorder; Major depressive disorder; Medicine; Psychiatry; Genetics; Psychology; Clinical psychology; Biology; Anxiety; Cognition","score_opus":0.024143949248008268,"score_gpt":0.24734474008775462,"score_spread":0.22320079083974634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973934110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975948,0.00084827654,0.000058537105,0.0006852702,0.00006628231,0.00037972187,0.00010435419,0.0000663671,0.0001964029],"genre_scores_gemma":[0.9981624,0.00004284902,0.00006804604,0.0007413786,0.00001720365,0.000057177513,0.0000112831995,0.000034596153,0.0008651036],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99861735,0.00011156677,0.00020560081,0.00045441504,0.00029898118,0.00031205872],"domain_scores_gemma":[0.9991755,0.00017170535,0.00018446617,0.00021963866,0.000051248004,0.00019745814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010385055,0.00022414193,0.0002810414,0.00007898671,0.0001271347,0.000049659662,0.00015670215,0.00010871844,0.000030212563],"category_scores_gemma":[0.00037040608,0.0001738448,0.000040042127,0.00026958622,0.0003895064,0.0001666756,0.00010854886,0.00013202641,0.000004061757],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028021567,0.0019364846,0.6776302,0.00004843676,0.000034198012,0.0001655391,0.0013969594,0.0000059826502,0.2983285,0.00047660552,0.0018372393,0.01785963],"study_design_scores_gemma":[0.008793475,0.00062008825,0.920417,0.000093337396,0.00014807125,0.00009640345,0.0011353304,0.000059293146,0.066741884,0.00026176445,0.0009491162,0.00068423554],"about_ca_topic_score_codex":0.000092515926,"about_ca_topic_score_gemma":0.00026577685,"teacher_disagreement_score":0.2427868,"about_ca_system_score_codex":0.00001281753,"about_ca_system_score_gemma":0.00004624371,"threshold_uncertainty_score":0.7089186},"labels":[],"label_agreement":null},{"id":"W1975336695","doi":"10.1002/jcb.10593","title":"Immune cell proliferation is suppressed by the interferon‐γ‐induced indoleamine 2,3‐dioxygenase expression of fibroblasts populated in collagen gel (FPCG)","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Sick Kids Foundation","keywords":"Indoleamine 2,3-dioxygenase; Kynurenine; Immune system; Peripheral blood mononuclear cell; Western blot; Interferon gamma; Cytokine; Interferon; Northern blot; Biology; Molecular biology; Messenger RNA; Chemistry; Immunology; Tryptophan; In vitro; Biochemistry; Amino acid; Gene","score_opus":0.01168216491886,"score_gpt":0.225552452732567,"score_spread":0.21387028781370698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975336695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985505,0.0005137782,0.00007686315,0.000117386335,0.00014330336,0.00018974405,0.00001587106,0.0000065597965,0.00038602372],"genre_scores_gemma":[0.99904585,0.000020274538,0.00006148065,0.000108020504,0.000030306715,0.0000027902875,0.0000042361366,0.000022257185,0.00070476986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99812937,0.0002085984,0.0007400403,0.00024082103,0.00044149207,0.00023965804],"domain_scores_gemma":[0.9987085,0.000058215257,0.0007005055,0.00035040712,0.0000919271,0.00009043804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002525512,0.0002013369,0.00028729448,0.00008481603,0.000065198365,0.000037066922,0.0004762884,0.0001931862,0.00012217493],"category_scores_gemma":[0.0004301495,0.00014994889,0.00016883352,0.00039364418,0.000073924755,0.00012226852,0.00006895044,0.00029093953,0.0000024761728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018042978,0.00032914727,0.0001121347,0.000098586126,0.0000041096973,0.000013244522,0.0002706655,0.000027411992,0.9974073,0.0000013098437,0.0015225213,0.00003309672],"study_design_scores_gemma":[0.0017689422,0.000120193545,0.00009354993,0.00020148307,0.0000050729504,0.000033941495,0.00020260202,0.00005320807,0.99723643,0.0000407151,0.000095688745,0.00014814394],"about_ca_topic_score_codex":0.0000041728117,"about_ca_topic_score_gemma":4.7181982e-7,"teacher_disagreement_score":0.0015885124,"about_ca_system_score_codex":0.0000625859,"about_ca_system_score_gemma":0.00014108622,"threshold_uncertainty_score":0.6114738},"labels":[],"label_agreement":null},{"id":"W1975679136","doi":"10.1016/j.bbr.2007.08.007","title":"Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys","year":2007,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":87,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"MPTP; Kynurenine; Benserazide; Pharmacology; Kynurenic acid; Levodopa; NMDA receptor; Glutamatergic; Metabolite; Microdialysis; Internal medicine; Chemistry; Endocrinology; Parkinson's disease; Medicine; Glutamate receptor; Receptor; Dopamine; Tryptophan; Biochemistry; Disease","score_opus":0.18941119180925997,"score_gpt":0.3962004216377126,"score_spread":0.2067892298284526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975679136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99601126,0.000032226762,0.000028110384,0.0018313598,0.00008831759,0.00086425553,0.0000074124323,0.0000685206,0.0010685393],"genre_scores_gemma":[0.99862456,0.0000060883767,0.00055843854,0.00010962397,0.00004371509,0.00007023493,0.000013514519,0.000036016623,0.00053778326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99570066,0.00049934315,0.0006839472,0.0006872983,0.0012890031,0.0011397526],"domain_scores_gemma":[0.9984484,0.00070969557,0.00014211137,0.0003368587,0.0001382227,0.00022473242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003209075,0.00023197534,0.00028248437,0.0009848523,0.00028938742,0.000058334805,0.0004369999,0.00018347237,0.00011596188],"category_scores_gemma":[0.0018312354,0.00021848435,0.000073056675,0.0017901505,0.0003227855,0.00024977393,0.00021867284,0.00071403745,0.000054339587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002672966,0.00046262675,0.0064812945,0.000023847651,0.0000020325836,0.00020772383,0.0018223508,0.0000022149839,0.9610779,0.00014206544,0.0003226315,0.02918797],"study_design_scores_gemma":[0.0010973021,0.0001755942,0.1915053,0.00008812888,0.0000011150468,0.000014479829,0.00051016465,0.000025623794,0.80606294,0.000121022415,0.00020454834,0.00019379219],"about_ca_topic_score_codex":0.00015262497,"about_ca_topic_score_gemma":0.0010432345,"teacher_disagreement_score":0.185024,"about_ca_system_score_codex":0.0002006435,"about_ca_system_score_gemma":0.000292559,"threshold_uncertainty_score":0.8909533},"labels":[],"label_agreement":null},{"id":"W1976699674","doi":"10.4161/21624046.2014.959425","title":"From head to tail it's a 2 way street for neuro-immune communication","year":2014,"lang":"en","type":"article","venue":"Worm","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kensington Health","funders":"","keywords":"Immune system; Neuroscience; Biology; Sensory system; Neurotransmitter; Nervous system; Central nervous system; Immunology","score_opus":0.03404196565097209,"score_gpt":0.28489262539903,"score_spread":0.25085065974805787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976699674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96254355,0.00006626812,0.003672128,0.021667816,0.00034786022,0.00060516363,0.000054668693,0.00018039753,0.010862156],"genre_scores_gemma":[0.9888643,0.000010925656,0.0012223842,0.009120746,0.000063064035,0.000053287244,0.000015032799,0.000017463037,0.0006327871],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99923337,0.000070057744,0.00014519083,0.00024119945,0.00011496096,0.00019520512],"domain_scores_gemma":[0.99873376,0.0005621762,0.00004730921,0.00057381124,0.000016441292,0.00006648629],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009783523,0.00009293393,0.000111261725,0.000041962507,0.00014253116,0.000050070776,0.0004594382,0.000036785525,0.000069813424],"category_scores_gemma":[0.00072325213,0.000088083485,0.000052450046,0.00015279789,0.00004679893,0.00008618231,0.00009903615,0.00008348314,0.00017717283],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023783279,0.00034224353,0.0003671819,0.000024223378,0.000007554815,0.0000014233943,0.00318822,0.00010617881,0.74932736,0.014725478,0.09181365,0.13985868],"study_design_scores_gemma":[0.0016084436,0.00026539163,0.011448503,0.00005248057,0.000007180957,8.435797e-7,0.00038432016,0.0018348988,0.19359016,0.0073622083,0.7831074,0.0003381881],"about_ca_topic_score_codex":0.00014880013,"about_ca_topic_score_gemma":0.0004742386,"teacher_disagreement_score":0.6912937,"about_ca_system_score_codex":0.0000138314745,"about_ca_system_score_gemma":0.000009497005,"threshold_uncertainty_score":0.359194},"labels":[],"label_agreement":null},{"id":"W1977078887","doi":"10.1002/mds.20596","title":"Effect of kynurenine 3‐hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in parkinsonian monkeys","year":2005,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Levodopa; Pharmacology; Kynurenic acid; Kynurenine; Dyskinesia; Ionotropic effect; Parkinson's disease; Dopamine; Parkinsonism; Glutamate receptor; MPTP; Internal medicine; Medicine; Chemistry; Receptor; Dopaminergic; Disease; Biochemistry; Tryptophan; Amino acid","score_opus":0.010222303083337655,"score_gpt":0.2516416731178628,"score_spread":0.24141937003452513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977078887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97899306,0.0000650514,0.000028573686,0.018428078,0.00005783381,0.00092176005,0.000018075152,0.000040165523,0.0014474146],"genre_scores_gemma":[0.9921087,0.000187899,0.000024968407,0.007308325,0.000022252942,0.00010065953,0.0000015368548,0.000024797007,0.00022083482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981057,0.00043183987,0.00028182662,0.00046536644,0.00034681094,0.00036848115],"domain_scores_gemma":[0.99881184,0.0006793019,0.00009009901,0.0003229983,0.000007781724,0.00008795361],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003997137,0.00024440917,0.00022457041,0.00029673544,0.00011405103,0.00004223635,0.00019067542,0.000050972954,0.00009342214],"category_scores_gemma":[0.0005894763,0.00017881207,0.00006294293,0.00052962033,0.00016602778,0.00009751372,0.00007715453,0.00015649135,0.000036318168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045259804,0.0013930849,0.039243363,0.00018752392,0.000024101175,0.000033479693,0.0034256415,0.0023846899,0.7155864,0.007217517,0.006813885,0.21916428],"study_design_scores_gemma":[0.0033891555,0.0024580196,0.06274814,0.00019491166,0.00001009846,6.522688e-7,0.00021811947,0.0013548573,0.9208092,0.0023641367,0.006044798,0.0004078915],"about_ca_topic_score_codex":0.00007850937,"about_ca_topic_score_gemma":0.00050268124,"teacher_disagreement_score":0.2187564,"about_ca_system_score_codex":0.00004735285,"about_ca_system_score_gemma":0.000014839163,"threshold_uncertainty_score":0.72917444},"labels":[],"label_agreement":null},{"id":"W1977080576","doi":"10.1016/j.ejphar.2015.01.006","title":"Blockade of NMDA receptors reverses the depressant, but not anxiogenic effect of adolescence social isolation in mice","year":2015,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Anxiogenic; NMDA receptor; Open field; Behavioural despair test; Anxiolytic; Pharmacology; Elevated plus maze; Blockade; Neurochemical; Psychology; Antidepressant; Receptor; Anxiety; Endocrinology; Internal medicine; Medicine; Neuroscience; Psychiatry","score_opus":0.0336716725455748,"score_gpt":0.297980351060749,"score_spread":0.2643086785151742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977080576","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99749124,0.00016078023,0.00007752128,0.00055812835,0.00089723716,0.00014817753,0.000005463357,0.0000066306925,0.000654816],"genre_scores_gemma":[0.999137,0.00010476296,0.00004670911,0.00041227863,0.00024079146,6.328776e-7,1.9814128e-7,0.000015956733,0.000041668027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99596184,0.0029209103,0.00053618854,0.00014384957,0.00024892934,0.000188285],"domain_scores_gemma":[0.9986434,0.00044115647,0.00070722215,0.00006519802,0.000083610415,0.00005943065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014432753,0.00011841458,0.00026838586,0.00015480563,0.000046900066,0.0000068877443,0.0005224814,0.0000285998,0.0000560755],"category_scores_gemma":[0.00060923456,0.0000846088,0.00011988359,0.00029817768,0.00029444552,0.00012862695,0.00008444893,0.00033790906,0.00001211025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011314829,0.00008794984,0.0018614699,0.000025958874,0.000013470239,0.000040737268,0.0009159116,0.00021815709,0.98831165,0.000008354768,0.0048848977,0.0024999776],"study_design_scores_gemma":[0.0031009587,0.0006064029,0.009888049,0.000031769603,0.000036092635,0.000051964093,0.00014635117,0.00008330523,0.9846839,0.000008626002,0.0012832879,0.000079330566],"about_ca_topic_score_codex":0.0000048025468,"about_ca_topic_score_gemma":0.0000015331653,"teacher_disagreement_score":0.008026579,"about_ca_system_score_codex":0.000028635919,"about_ca_system_score_gemma":0.00007177679,"threshold_uncertainty_score":0.34502468},"labels":[],"label_agreement":null},{"id":"W1977295539","doi":"10.1136/jech-2014-205217.6","title":"DEPRESSIVE SYMPTOMS, C-REACTIVE PROTEIN, AND INCIDENCE OF DIABETES","year":2014,"lang":"en","type":"article","venue":"Journal of Epidemiology & Community Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Medicine; Diabetes mellitus; Incidence (geometry); Depression (economics); Internal medicine; C-reactive protein; Center for Epidemiologic Studies Depression Scale; Type 2 diabetes; Depressive symptoms; Endocrinology; Inflammation","score_opus":0.058109603791550425,"score_gpt":0.3537650056529445,"score_spread":0.29565540186139405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977295539","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99365264,0.0008902338,0.0008419744,0.0039709625,0.00009326318,0.00018063714,0.000005129986,0.000011162623,0.0003539866],"genre_scores_gemma":[0.9925601,0.00019529408,0.0009462989,0.0062333345,0.000043636497,0.0000036389717,5.8062045e-7,0.0000095065525,0.000007598335],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9895927,0.0088244695,0.0009249571,0.00015396193,0.00013239509,0.00037154127],"domain_scores_gemma":[0.98358154,0.013738816,0.0018750518,0.0004406928,0.00012775426,0.00023615113],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.00624094,0.00014018519,0.000794878,0.00015692395,0.00030745284,0.0000050876824,0.000529963,0.00010772582,0.000008723891],"category_scores_gemma":[0.038438607,0.00010951513,0.000093852046,0.00015102696,0.0006641419,0.00020216532,0.00017587833,0.0012492436,0.0000016513717],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002587971,0.0008897313,0.7357482,0.0006371761,0.000091937996,0.0000034377254,0.0035428763,0.00016023203,0.17524762,0.0261115,0.0018567004,0.055451836],"study_design_scores_gemma":[0.0017698049,0.0042873793,0.85926014,0.00092946744,0.000020500309,0.00009343223,0.0005375276,0.0005750934,0.0462421,0.08382346,0.002189676,0.00027140795],"about_ca_topic_score_codex":0.00048515844,"about_ca_topic_score_gemma":0.00018279807,"teacher_disagreement_score":0.12900552,"about_ca_system_score_codex":0.000059988386,"about_ca_system_score_gemma":0.00019142313,"threshold_uncertainty_score":0.96966106},"labels":[],"label_agreement":null},{"id":"W1977380476","doi":"10.1111/j.0022-202x.2004.22409.x","title":"Expression of Indoleamine 2,3-Dioxygenase in Dermal Fibroblasts Functions as a Local Immunosuppressive Factor","year":2004,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta; Canadian Institutes of Health Research; Hospital for Sick Children; University of Miami","keywords":"Indoleamine 2,3-dioxygenase; Immune system; Propidium iodide; Jurkat cells; Biology; Cell biology; Apoptosis; CD8; Immunology; Cancer research; Programmed cell death; T cell","score_opus":0.02182199340180982,"score_gpt":0.26109277043558127,"score_spread":0.23927077703377145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977380476","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99702513,0.00019637948,0.0011444936,0.0010147007,0.00015602077,0.0001430324,0.000019426414,0.000012230172,0.000288584],"genre_scores_gemma":[0.99871475,0.000024536212,0.00048648968,0.0007051248,0.000026706406,0.000005442695,0.0000015757353,0.000016354938,0.000019031995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980418,0.00034261536,0.00078494137,0.00021788092,0.0003075829,0.00030515165],"domain_scores_gemma":[0.9984015,0.00036601367,0.00073942373,0.00016392855,0.00014683671,0.00018224881],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006555135,0.00020245534,0.00047675156,0.00044905872,0.00007377033,0.0000137347115,0.00032790142,0.00015813764,0.00007364657],"category_scores_gemma":[0.0014524331,0.00016591951,0.00014313178,0.0004458667,0.0010792868,0.00043609162,0.00009019694,0.0005228447,0.000029030867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020567629,0.00022458137,0.00017734905,0.000035895315,0.0000106971365,0.0005167636,0.0019958124,0.001513499,0.9941814,0.0007365461,0.00023870516,0.00016309046],"study_design_scores_gemma":[0.0027992476,0.0002982183,0.009598102,0.00026615759,0.0000033464512,0.002056756,0.0011880049,0.000024861603,0.9789791,0.0045127785,0.00013287654,0.00014054729],"about_ca_topic_score_codex":0.000021007227,"about_ca_topic_score_gemma":0.000017381833,"teacher_disagreement_score":0.015202282,"about_ca_system_score_codex":0.00007493768,"about_ca_system_score_gemma":0.00040041952,"threshold_uncertainty_score":0.67660016},"labels":[],"label_agreement":null},{"id":"W1977657096","doi":"10.1155/2012/609421","title":"Preclinical and Clinical Evidence of Antioxidant Effects of Antidepressant Agents: Implications for the Pathophysiology of Major Depressive Disorder","year":2012,"lang":"en","type":"review","venue":"Oxidative Medicine and Cellular Longevity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":203,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Antidepressant; Major depressive disorder; Oxidative stress; Medicine; Neuroprotection; Pathophysiology; Pharmacology; Antioxidant; Animal studies; Internal medicine; Depression (economics); Animal models of depression; Psychiatry; Bioinformatics; Cognition; Biology; Hippocampus; Biochemistry","score_opus":0.1467757131329936,"score_gpt":0.41925313487500315,"score_spread":0.27247742174200956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977657096","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02696019,0.96688855,0.0033821794,0.0001690311,0.00021237793,0.0022635974,0.000099193465,0.000008128919,0.000016763015],"genre_scores_gemma":[0.11972624,0.879842,0.000083002364,0.000063665444,0.0001060764,0.00012526613,0.00001089706,0.000023991997,0.00001887134],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99634165,0.0012107932,0.0013039663,0.00066313084,0.00020719194,0.0002732678],"domain_scores_gemma":[0.9775158,0.019933209,0.001620819,0.0006785532,0.00013038749,0.000121190824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010118173,0.00036039995,0.0022010216,0.000098767756,0.00011076108,0.0000046138944,0.0004680664,0.00026158098,0.000018220879],"category_scores_gemma":[0.0073131328,0.00019955201,0.00040935405,0.00027607326,0.0027067107,0.00010559731,0.0003110634,0.00035238467,7.173783e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000103516606,0.0005792795,0.0029514018,0.030779475,0.0002575882,0.000002616169,0.0002234588,1.2753242e-7,0.017337311,0.0009000592,0.00012719234,0.94673795],"study_design_scores_gemma":[0.020902665,0.016075075,0.39775082,0.16724494,0.043950185,0.00011838371,0.0008334879,0.00024060663,0.07412051,0.01082275,0.26376006,0.0041804984],"about_ca_topic_score_codex":0.000032164997,"about_ca_topic_score_gemma":0.0000053367116,"teacher_disagreement_score":0.94255745,"about_ca_system_score_codex":0.000006259686,"about_ca_system_score_gemma":0.00008400693,"threshold_uncertainty_score":0.99729884},"labels":[],"label_agreement":null},{"id":"W1977753547","doi":"10.1152/ajprenal.00567.2007","title":"Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury","year":2008,"lang":"en","type":"article","venue":"American Journal of Physiology-Renal Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Western University","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Kynurenine; Renal ischemia; Creatinine; Kynurenine pathway; Kidney; Medicine; Reperfusion injury; Renal function; Acute kidney injury; Ischemia; In vitro; Internal medicine; Downregulation and upregulation; Endocrinology; Inflammation; Pharmacology; Chemistry; Tryptophan; Biochemistry","score_opus":0.015354904485386853,"score_gpt":0.2542104197461934,"score_spread":0.23885551526080656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977753547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99880993,0.00011519004,0.000061905244,0.0002596759,0.00030561458,0.00017095006,0.00002064391,0.00006453599,0.00019154587],"genre_scores_gemma":[0.9962257,0.00033809483,0.0008004369,0.001681595,0.00078266,0.000011578001,0.000009242945,0.00004883003,0.0001018465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99651456,0.00071495987,0.00088430755,0.0007174191,0.00042256052,0.0007461709],"domain_scores_gemma":[0.99711454,0.00050333,0.0013616795,0.0005126484,0.00018975366,0.00031802058],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002046001,0.00047029246,0.0010473478,0.00034263168,0.0003518845,0.000011756839,0.00089187745,0.00016055141,0.00035552346],"category_scores_gemma":[0.0006476597,0.00034835347,0.00042411976,0.00066380523,0.0022246654,0.0003607284,0.00028522426,0.0009177012,0.000090185094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017020915,0.0004658343,0.0000210399,0.000013958875,0.000029395913,0.00004936444,0.00032871097,0.00012994728,0.9897868,0.000038249545,0.0035269447,0.003907645],"study_design_scores_gemma":[0.001181923,0.003095405,0.0055901436,0.00007992342,0.000008175459,0.0004526607,0.00013821009,0.000051632444,0.98675215,0.0009959097,0.00127686,0.0003769939],"about_ca_topic_score_codex":0.000018239536,"about_ca_topic_score_gemma":7.767657e-7,"teacher_disagreement_score":0.0055691036,"about_ca_system_score_codex":0.000056056084,"about_ca_system_score_gemma":0.00023610065,"threshold_uncertainty_score":0.9998968},"labels":[],"label_agreement":null},{"id":"W1977764668","doi":"10.1016/j.euroneuro.2011.08.001","title":"Prenatal exposure to bacterial endotoxin reduces the number of GAD67- and reelin-immunoreactive neurons in the hippocampus of rat offspring","year":2011,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Reelin; Dentate gyrus; Glutamate decarboxylase; Offspring; DAB1; Hippocampus; Endocrinology; Internal medicine; Schizophrenia (object-oriented programming); Pregnancy; Biology; Neuroscience; Psychology; Medicine; Psychiatry; Biochemistry; Enzyme; Genetics; Receptor","score_opus":0.028249397436614775,"score_gpt":0.27987788244296435,"score_spread":0.2516284850063496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977764668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861973,0.000042861964,0.0000022659378,0.00040524034,0.0012593777,0.0006237345,0.000014007231,0.00004229241,0.01141295],"genre_scores_gemma":[0.9975593,0.00011865513,0.00004853011,0.0020352225,0.000106952306,0.000022479768,7.2638886e-7,0.000054330678,0.000053807948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960081,0.002427445,0.0004926624,0.0005144257,0.00020410855,0.0003532808],"domain_scores_gemma":[0.9985671,0.00064760377,0.0002507424,0.0004290242,0.00003401185,0.00007152887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047955816,0.00023085243,0.00024973243,0.00011395163,0.00008660308,0.000021971857,0.0009911284,0.00003461695,0.0001436381],"category_scores_gemma":[0.00039813775,0.00015420714,0.00007974819,0.00043243685,0.0005105543,0.00012758192,0.0002691805,0.0004184985,0.000032687094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010168013,0.0002551652,0.00046624764,0.000017688026,0.000008415374,0.00012869255,0.0053989813,0.0000065991044,0.9867398,0.00018094791,0.0004649952,0.0053156414],"study_design_scores_gemma":[0.0033217384,0.0007646845,0.2940333,0.0000448545,0.000034123543,0.0003104551,0.00071422214,0.000013079324,0.6975006,0.0002753347,0.0026826265,0.00030500002],"about_ca_topic_score_codex":0.00001865196,"about_ca_topic_score_gemma":0.0000041506632,"teacher_disagreement_score":0.29356703,"about_ca_system_score_codex":0.0000066727384,"about_ca_system_score_gemma":0.000027542785,"threshold_uncertainty_score":0.6288385},"labels":[],"label_agreement":null},{"id":"W1977959548","doi":"10.1017/s1461145713000229","title":"Prenatal immune activation interacts with stress and corticosterone exposure later in life to modulate N-methyl-d-aspartate receptor synaptic function and plasticity","year":2013,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Prenatal stress; NMDA receptor; Offspring; Corticosterone; Hippocampal formation; Schizophrenia (object-oriented programming); Endocrinology; Hippocampus; Synaptic plasticity; Internal medicine; Glutamatergic; Psychosis; Long-term potentiation; Neuroscience; Psychology; Glutamate receptor; Pregnancy; Medicine; Receptor; Biology; Hormone; Psychiatry","score_opus":0.014535278249791951,"score_gpt":0.26275210198326016,"score_spread":0.2482168237334682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977959548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99237907,0.000029884732,0.00016706545,0.0062115355,0.00091140595,0.00026099003,0.0000054512775,0.0000098725095,0.000024735618],"genre_scores_gemma":[0.9958637,0.00007359261,0.000047844333,0.0038421808,0.000108792425,0.000014151777,7.459102e-7,0.000014825613,0.000034197496],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99881005,0.00019093638,0.00036862335,0.00020707732,0.00025522456,0.00016807283],"domain_scores_gemma":[0.9989486,0.00046777088,0.0002776182,0.000060464852,0.00013106839,0.00011450122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010121096,0.00013381988,0.00016023399,0.00020915536,0.00004541181,0.00009567249,0.0002755794,0.000034320437,0.00014134026],"category_scores_gemma":[0.00029706903,0.00008859365,0.000022076938,0.0001177549,0.000104481136,0.00045438687,0.00009014746,0.00032602195,0.000017074848],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028141204,0.00013506113,0.001365732,0.000010070388,0.00005809167,0.000026423995,0.00039339633,0.0012385286,0.99074453,0.000021468242,0.00012894235,0.0030636096],"study_design_scores_gemma":[0.0058765924,0.0016925436,0.741579,0.00020741324,0.000029512072,0.0003050021,0.00019328354,0.0020679596,0.2473565,0.00034260686,0.00013294393,0.00021664833],"about_ca_topic_score_codex":0.000014769883,"about_ca_topic_score_gemma":0.000006048827,"teacher_disagreement_score":0.74338806,"about_ca_system_score_codex":0.000027059114,"about_ca_system_score_gemma":0.000023791928,"threshold_uncertainty_score":0.36127445},"labels":[],"label_agreement":null},{"id":"W1979603195","doi":"10.1111/jnc.12316","title":"Specific subcellular changes in oxidative stress in prefrontal cortex from patients with bipolar disorder","year":2013,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":146,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Toronto; University of Manitoba; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Peroxynitrite; Oxidative stress; Nitrotyrosine; Lipid peroxidation; Protein Carbonylation; Mitochondrion; Chemistry; Prefrontal cortex; Oxidative phosphorylation; Bipolar disorder; Biochemistry; Internal medicine; Endocrinology; Biology; Nitric oxide synthase; Neuroscience; Superoxide; Medicine; Enzyme; Lithium (medication)","score_opus":0.009796861015192357,"score_gpt":0.2014626624858964,"score_spread":0.19166580147070403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979603195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990268,0.00034515298,0.00001225091,0.00015615077,0.00010031711,0.00016334082,0.000031474327,0.000007763443,0.00015680032],"genre_scores_gemma":[0.99952656,0.00013360275,0.000054477252,0.00013359077,0.000062386076,0.0000054766724,0.0000071872096,0.000022081049,0.00005462841],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986501,0.00007037733,0.00033077222,0.00028917228,0.00039281702,0.00026681376],"domain_scores_gemma":[0.99921966,0.00013235696,0.00030313426,0.00017963434,0.000060008482,0.00010521818],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000037525846,0.00018677521,0.00024781658,0.000117378106,0.000028944314,0.000054021486,0.00037553225,0.00007305641,0.0002730639],"category_scores_gemma":[0.000121223005,0.00014981782,0.000045201265,0.00026602094,0.000099067984,0.00028540002,0.00005478811,0.00044844244,0.000012453197],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009992413,0.00050194096,0.13050175,0.000013324337,0.0000033894464,0.00009173458,0.00026061642,0.000015740754,0.86750966,9.570269e-7,0.000086596265,0.0009143595],"study_design_scores_gemma":[0.0016835497,0.0001468398,0.5782429,0.00008512283,0.0000024320655,0.0000067404812,0.0002634975,0.000023875153,0.41886735,0.000053784657,0.00047718518,0.00014670656],"about_ca_topic_score_codex":0.000044358516,"about_ca_topic_score_gemma":0.000060164934,"teacher_disagreement_score":0.4486423,"about_ca_system_score_codex":0.00004779592,"about_ca_system_score_gemma":0.000034788503,"threshold_uncertainty_score":0.6109393},"labels":[],"label_agreement":null},{"id":"W1979634677","doi":"10.1016/j.imbio.2013.06.008","title":"IDO expressing fibroblasts promote the expansion of antigen specific regulatory T cells","year":2013,"lang":"en","type":"article","venue":"Immunobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"FOXP3; IL-2 receptor; Antigen; Immunology; Immune tolerance; Immune system; Mixed lymphocyte reaction; Population; Cell biology; Cancer research; Biology; Chemistry; Medicine; T cell","score_opus":0.018162106635817913,"score_gpt":0.22871518429428148,"score_spread":0.21055307765846357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979634677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99722874,0.0005855819,0.00006494416,0.0002263968,0.00041349436,0.00032794962,0.000004035737,0.00004650907,0.0011023736],"genre_scores_gemma":[0.9990234,0.00017031225,0.00019596326,0.0002489262,0.00004056702,0.000013874074,0.0000016941636,0.000015256007,0.00029004723],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988771,0.00020180683,0.00024881255,0.00029407808,0.00009089867,0.0002873101],"domain_scores_gemma":[0.99914324,0.00016458312,0.00013955461,0.0004982624,0.000028296321,0.000026081776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001073223,0.00012856806,0.00016687489,0.000052008138,0.00013936394,0.000026911333,0.0004312088,0.00009665844,0.0004389734],"category_scores_gemma":[0.000051119434,0.00008376693,0.000072282615,0.00014072369,0.0004957682,0.0001257727,0.00013316766,0.0001329083,0.00030699192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014813626,0.000026186537,0.00003340943,0.0000060440307,0.0000025613072,0.0000010340906,0.00038714104,0.000009535429,0.98914146,0.00022240369,0.0015406726,0.008614726],"study_design_scores_gemma":[0.0002309443,0.00007758117,0.010292292,0.0000270886,6.914756e-7,0.000010794156,0.00012479615,0.000034577613,0.9768168,0.00071455055,0.0115695195,0.00010038731],"about_ca_topic_score_codex":0.000020993077,"about_ca_topic_score_gemma":6.3198416e-7,"teacher_disagreement_score":0.012324695,"about_ca_system_score_codex":0.000010344694,"about_ca_system_score_gemma":0.000025692316,"threshold_uncertainty_score":0.4806451},"labels":[],"label_agreement":null},{"id":"W1979776656","doi":"10.3899/jrheum.121035","title":"Kynurenic Acid in Synovial Fluid and Serum of Patients with Rheumatoid Arthritis, Spondyloarthropathy, and Osteoarthritis","year":2013,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Spondyloarthropathy; Synovial fluid; Osteoarthritis; Rheumatoid arthritis; Arthropathy; Synovitis; Kynurenic acid; Arthritis; Internal medicine; Pathology","score_opus":0.00525955734261399,"score_gpt":0.19238276488157355,"score_spread":0.18712320753895956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979776656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996325,0.002767891,0.000018816138,0.00045415922,0.0001519673,0.00022070123,0.0000109424445,0.0000070357914,0.00004349697],"genre_scores_gemma":[0.99314666,0.006663655,0.0000655591,0.00009973472,0.0000025143638,0.0000030145495,4.2036e-7,0.000014701066,0.0000037391644],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985294,0.00030168533,0.0005301512,0.00014910009,0.00022170374,0.0002680108],"domain_scores_gemma":[0.9989652,0.0003214677,0.00039378778,0.00015426244,0.00007849248,0.000086768836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024339504,0.00015386101,0.00043851056,0.00017364333,0.00008004637,0.000023343757,0.00021141584,0.000075317206,0.00009623179],"category_scores_gemma":[0.00028383435,0.000100576755,0.000032414126,0.0001851606,0.0006707551,0.00030432284,0.0000822001,0.00024912704,0.0000073166834],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011980111,0.00032481874,0.8800855,0.000083933686,0.000026602776,0.000030624033,0.0033390739,0.000010162712,0.033677142,0.0014999232,0.00037657522,0.079347625],"study_design_scores_gemma":[0.025722142,0.005385616,0.905047,0.0013217014,0.000018368482,0.012453408,0.0022364936,0.000090317306,0.040900584,0.0056124968,0.0005432226,0.0006686457],"about_ca_topic_score_codex":0.00006549997,"about_ca_topic_score_gemma":0.00019646267,"teacher_disagreement_score":0.07867898,"about_ca_system_score_codex":0.00000851229,"about_ca_system_score_gemma":0.00005072913,"threshold_uncertainty_score":0.4101401},"labels":[],"label_agreement":null},{"id":"W1980046832","doi":"10.3109/08820139.2012.689405","title":"Host Indoleamine 2,3-Dioxygenase: Contribution to Systemic Acquired Tumor Tolerance","year":2012,"lang":"en","type":"review","venue":"Immunological Investigations","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Calgary","keywords":"Indoleamine 2,3-dioxygenase; Immune tolerance; Immunology; Immune system; Biology; Stromal cell; Immunologic Tolerance; Cancer research; Transplantation; Endogeny; Mechanism (biology); Tumor microenvironment; Medicine","score_opus":0.09975539380441428,"score_gpt":0.3209720692036441,"score_spread":0.2212166753992298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980046832","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0045186253,0.99116266,0.00017877511,0.00015443437,0.00077979406,0.0021389383,0.00036742567,0.00042968575,0.00026966556],"genre_scores_gemma":[0.039755322,0.95617884,0.00026121864,0.0013777827,0.0004021082,0.0013188457,0.00022171608,0.0000733708,0.00041082004],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961745,0.00081381743,0.0009667458,0.0007476023,0.00035077837,0.00094651675],"domain_scores_gemma":[0.99749935,0.000772116,0.0005012522,0.00072138483,0.0000844167,0.00042145772],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029957652,0.0006367584,0.0014048517,0.00027342443,0.0004074812,0.00012760064,0.00089172315,0.00047489587,0.0002183735],"category_scores_gemma":[0.0031596292,0.0004917514,0.00039816473,0.0015323302,0.0005516024,0.00029758355,0.00028690512,0.00052906363,0.003298333],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009086029,0.0021279952,0.000033016753,0.013590533,0.00031644784,0.00011832045,0.00066648563,0.000045385535,0.21509247,0.14984915,0.0025726375,0.6154967],"study_design_scores_gemma":[0.00035628033,0.00008745353,0.00013608554,0.0041147624,0.00010204846,0.00023142535,0.000019593655,0.0000045287497,0.0058431677,0.00013583187,0.9882448,0.0007240532],"about_ca_topic_score_codex":0.0000059874183,"about_ca_topic_score_gemma":0.0000012309447,"teacher_disagreement_score":0.9856721,"about_ca_system_score_codex":0.00027477814,"about_ca_system_score_gemma":0.00019405391,"threshold_uncertainty_score":0.9997534},"labels":[],"label_agreement":null},{"id":"W1980841783","doi":"10.1002/biot.200600001","title":"Inhibitors of human indoleamine 2,3‐dioxygenase identified with a target‐based screen in yeast","year":2006,"lang":"en","type":"article","venue":"Biotechnology Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Yeast; Computational biology; Biology; Chemistry; Microbiology; Biochemistry; Tryptophan","score_opus":0.013261671291581895,"score_gpt":0.23552068882633972,"score_spread":0.22225901753475782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980841783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974475,0.00009102078,0.00080867845,0.00086532417,0.000068591,0.00014075107,0.000011328687,0.00007693229,0.00048986264],"genre_scores_gemma":[0.9990358,0.000005661477,0.000671425,0.00011532348,0.000057911773,0.000003674792,0.0000023755974,0.000019322219,0.000088551635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986676,0.00007658164,0.0003960236,0.00027248717,0.00025065546,0.00033667847],"domain_scores_gemma":[0.9993989,0.000028860622,0.00026412233,0.00023076725,0.000029642038,0.00004770707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001875338,0.00015549283,0.00023117605,0.00075527356,0.00012974947,0.000028678258,0.0003770543,0.00024799252,0.00006187878],"category_scores_gemma":[0.000114775125,0.0001275857,0.0000641817,0.00074784714,0.0005342252,0.00010932207,0.000049854058,0.00054981274,0.0000110547635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000077009914,0.0002562297,0.002722416,0.000008452278,0.000003188495,0.0002020001,0.000015300922,0.000115944335,0.9940012,0.0016097435,0.00044326822,0.00054526585],"study_design_scores_gemma":[0.0020559453,0.00025431707,0.011158764,0.0000636536,0.0000021956241,0.00014056118,0.00008628002,0.000076519995,0.98438555,0.0012793613,0.00035052476,0.00014631246],"about_ca_topic_score_codex":0.00006922867,"about_ca_topic_score_gemma":0.00018253236,"teacher_disagreement_score":0.009615617,"about_ca_system_score_codex":0.00004103966,"about_ca_system_score_gemma":0.0000758875,"threshold_uncertainty_score":0.5202794},"labels":[],"label_agreement":null},{"id":"W1980932033","doi":"10.1016/j.pneurobio.2011.08.008","title":"Autoimmune and inflammatory mechanisms of CNS damage","year":2011,"lang":"en","type":"review","venue":"Progress in Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":78,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Neuroscience; Autoimmunity; Immune system; Inflammation; Central nervous system; Neuroimmunology; Immunology; Immunity; Biology; Function (biology); Medicine","score_opus":0.04994641908044818,"score_gpt":0.3085620007186095,"score_spread":0.25861558163816134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980932033","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007710738,0.9971855,0.0000059274744,0.000011648399,0.0004387214,0.00079163956,0.00003121537,0.00007628413,0.0006879825],"genre_scores_gemma":[0.0026101125,0.9969412,0.00010077993,0.0000699302,0.000014912243,0.00014364325,0.000008846961,0.000051786345,0.000058765843],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99756277,0.00064985064,0.0006541896,0.000678195,0.000062970634,0.00039203174],"domain_scores_gemma":[0.9986864,0.00032161607,0.00047876756,0.000451358,0.000012723483,0.00004914266],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018076935,0.00037422802,0.0012338089,0.00035700953,0.00003864327,0.000012400308,0.0006341175,0.00038618234,0.000057016143],"category_scores_gemma":[0.0001880243,0.00030414056,0.00015603051,0.00030050997,0.000783941,0.00006009474,0.00044111797,0.00049571047,0.000025386718],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014823391,0.00013630764,0.00005360365,0.0068371072,0.000012280299,0.00007048295,0.00008498184,4.7038693e-8,0.0003423379,0.04352565,0.000015497453,0.9489069],"study_design_scores_gemma":[0.0008596235,0.0005769288,0.0009785206,0.005136285,0.00010575698,0.00025892927,0.000012323896,0.0000075894286,0.0020902306,0.0063907257,0.9826082,0.0009748639],"about_ca_topic_score_codex":0.0000017619141,"about_ca_topic_score_gemma":0.0000029010494,"teacher_disagreement_score":0.9825927,"about_ca_system_score_codex":0.000012278099,"about_ca_system_score_gemma":0.00008858187,"threshold_uncertainty_score":0.99994105},"labels":[],"label_agreement":null},{"id":"W1981234240","doi":"10.1016/j.plefa.2006.11.003","title":"Biomarkers of oxidative stress in schizophrenic and control subjects","year":2007,"lang":"en","type":"article","venue":"Prostaglandins Leukotrienes and Essential Fatty Acids","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NOSM University; Lakehead University","funders":"","keywords":"Oxidative stress; Schizophrenia (object-oriented programming); Lipid peroxidation; DNA damage; Internal medicine; Vitamin E; Pathophysiology; Vitamin C; Endocrinology; Oxidative damage; Vitamin; Medicine; Antioxidant; DNA; Biology; Biochemistry; Psychiatry","score_opus":0.011747438473191655,"score_gpt":0.25102461705920226,"score_spread":0.2392771785860106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981234240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99599904,0.0006080633,0.0023007668,0.000108647226,0.00013793305,0.00038761302,0.00007436716,0.000032600747,0.0003509742],"genre_scores_gemma":[0.9993681,0.00034645226,0.00012443057,0.00007719171,0.000037918846,0.000008561752,0.000006563384,0.0000150096275,0.000015790363],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855226,0.00007157774,0.00032609416,0.00043695187,0.00021387014,0.00039925057],"domain_scores_gemma":[0.9992886,0.00029315436,0.00011987464,0.00014645605,0.000027268808,0.0001246404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002912079,0.00019664719,0.0002846265,0.0002700793,0.000117957956,0.000055133845,0.00012728322,0.0001075214,0.000016191452],"category_scores_gemma":[0.00021883912,0.00017109387,0.000045857545,0.00045905582,0.00044139058,0.00023019663,0.00008323085,0.00013265382,0.000001481709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016146996,0.00015876985,0.20981453,0.00012129022,0.000028285045,0.00004341366,0.0008362495,0.000006117369,0.77728915,0.003602085,0.0000057738653,0.006479627],"study_design_scores_gemma":[0.0045317975,0.00017803416,0.11057146,0.000059556958,0.000015932994,0.000016661954,0.0006242674,0.00021620856,0.8828526,0.0006380091,0.000067110646,0.00022832137],"about_ca_topic_score_codex":0.00010123394,"about_ca_topic_score_gemma":0.00027581918,"teacher_disagreement_score":0.105563484,"about_ca_system_score_codex":0.000016494683,"about_ca_system_score_gemma":0.00003923309,"threshold_uncertainty_score":0.6977005},"labels":[],"label_agreement":null},{"id":"W1981424354","doi":"10.1016/j.bbr.2014.05.058","title":"Potential benefits of mindfulness-based interventions in mild cognitive impairment and Alzheimer's disease: An interdisciplinary perspective","year":2014,"lang":"en","type":"review","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":93,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut Universitaire en Santé Mentale de Québec; Université Laval","funders":"","keywords":"Psychology; Neuroscience; Mindfulness; Psychological intervention; Disease; Cognition; Context (archaeology); Alzheimer's disease; Neurodegeneration; Clinical psychology; Medicine; Psychiatry; Internal medicine","score_opus":0.20543557649314056,"score_gpt":0.4757041304418011,"score_spread":0.27026855394866056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981424354","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03556532,0.9584549,0.0000478891,0.0006981201,0.00017226848,0.0036124673,0.0012822668,0.00005339391,0.000113378665],"genre_scores_gemma":[0.8509176,0.14621097,0.00003492234,0.00008750313,0.0001422339,0.0017373388,0.00041056308,0.00018459752,0.000274284],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.99337643,0.0026950608,0.0008459354,0.0013095381,0.0009683504,0.0008046832],"domain_scores_gemma":[0.9969374,0.0015369103,0.00029317592,0.00052333716,0.0002600353,0.00044916145],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001354933,0.0005056579,0.0011735747,0.0015499627,0.00033918457,0.00013871084,0.00080651883,0.0002753068,0.00021048012],"category_scores_gemma":[0.0007846704,0.00044365917,0.0007357121,0.001069456,0.0011708228,0.00023238212,0.0010102375,0.001172768,0.00002717096],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071847485,0.0040123607,0.00021214099,0.008320568,0.000089243076,0.00031381333,0.000832085,0.0000104307,0.000015553165,0.0034204996,0.00055620255,0.9814986],"study_design_scores_gemma":[0.037056174,0.028289303,0.2404331,0.59017676,0.0078099356,0.00055539224,0.035174113,0.0025207247,0.007177164,0.023106592,0.01298827,0.014712462],"about_ca_topic_score_codex":0.00017865375,"about_ca_topic_score_gemma":0.00022465987,"teacher_disagreement_score":0.96678615,"about_ca_system_score_codex":0.00020183904,"about_ca_system_score_gemma":0.00044199376,"threshold_uncertainty_score":0.9998015},"labels":[],"label_agreement":null},{"id":"W1981575054","doi":"10.1038/mt.2011.189","title":"Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation","year":2011,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":710,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Bystander effect; Indoleamine 2,3-dioxygenase; Macrophage; Cytokine; Biology; Immunology; Cell biology; Tryptophan; Genetics; In vitro","score_opus":0.026491362023143276,"score_gpt":0.23759447660627814,"score_spread":0.21110311458313485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981575054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997506,0.00023036562,0.0015808002,0.000020569783,0.000050986182,0.00024413694,0.000006976553,0.00004393789,0.00031621274],"genre_scores_gemma":[0.99952793,0.00008514493,0.00009067309,0.00014450122,0.000010263304,0.000011071603,0.0000074900017,0.000025997653,0.00009692536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991165,0.00010227238,0.00015388092,0.00028099385,0.00019424019,0.00015211414],"domain_scores_gemma":[0.9995905,0.000013766901,0.0001138679,0.00020448565,0.000027000084,0.00005037409],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000050170976,0.00014762997,0.00014208599,0.00009874098,0.0000884,0.000017613724,0.00010335056,0.00007464086,0.00014655598],"category_scores_gemma":[0.000015993175,0.000109089575,0.00003474408,0.00016904176,0.00012732469,0.00010744279,0.000025026704,0.00011268531,0.0000026867015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019237312,0.00017544503,0.00044498342,0.0000121307885,0.00001180316,0.000019567087,0.0007452125,0.000003832369,0.99574375,0.0004917998,0.000013281418,0.0021457965],"study_design_scores_gemma":[0.0018141933,0.00039744866,0.020806566,0.000025603571,0.0000032931537,0.000012902578,0.000082790604,0.000043962387,0.9760138,0.0006295198,0.000039338254,0.00013057288],"about_ca_topic_score_codex":0.000017553728,"about_ca_topic_score_gemma":0.000002719223,"teacher_disagreement_score":0.020361584,"about_ca_system_score_codex":0.000008788412,"about_ca_system_score_gemma":0.000007815037,"threshold_uncertainty_score":0.44485438},"labels":[],"label_agreement":null},{"id":"W1981814313","doi":"10.1111/cea.12498","title":"Respiratory syncytial virus induces indoleamine 2,3‐dioxygenase activity: a potential novel role in the development of allergic disease","year":2015,"lang":"en","type":"article","venue":"Clinical & Experimental Allergy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Saskatchewan; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Indoleamine 2,3-dioxygenase; Immune system; Immunology; Biology; Mononegavirales; Virus; Paramyxoviridae; Viral disease; Biochemistry","score_opus":0.13030227553874119,"score_gpt":0.3693329398911263,"score_spread":0.23903066435238512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981814313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99753445,0.0004306002,0.00006215841,0.0001569607,0.00039227464,0.00036240637,0.000014325856,0.000043315784,0.0010035255],"genre_scores_gemma":[0.99784297,0.000012477257,0.0001749872,0.001606609,0.00019094255,0.00009175121,0.0000048301454,0.000028215669,0.000047224978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968998,0.00046619977,0.000835545,0.0006674263,0.00072405994,0.0004070142],"domain_scores_gemma":[0.99863935,0.0002720564,0.0002456782,0.0004440276,0.000030311392,0.00036857056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065973744,0.00027899898,0.00038286645,0.000112615824,0.00011421367,0.000044382534,0.0007609995,0.00014145694,0.00007315813],"category_scores_gemma":[0.00061633176,0.00021310504,0.00018789002,0.00030519246,0.00044233084,0.00022364875,0.00036859352,0.00034994245,0.000056650657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016886118,0.0060987324,0.00007219143,0.000006922476,0.000024843963,0.000079544334,0.0026213138,0.00006902622,0.9842642,0.0003555667,0.00026958293,0.004449447],"study_design_scores_gemma":[0.0051611625,0.00051251455,0.02065539,0.000033579603,0.000003206057,0.000004353835,0.0030235494,0.00024355535,0.96115166,0.00014252501,0.008667292,0.0004012293],"about_ca_topic_score_codex":0.00003575482,"about_ca_topic_score_gemma":0.000066370565,"teacher_disagreement_score":0.023112573,"about_ca_system_score_codex":0.00007450615,"about_ca_system_score_gemma":0.00047241533,"threshold_uncertainty_score":0.8690171},"labels":[],"label_agreement":null},{"id":"W1982232007","doi":"10.1371/journal.pone.0071044","title":"Immuno-Regulatory Function of Indoleamine 2,3 Dioxygenase through Modulation of Innate Immune Responses","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research","keywords":"Indoleamine 2,3-dioxygenase; Proinflammatory cytokine; Kynurenine; Immune system; Islet; Transplantation; Cancer research; Immunology; Apoptosis; Viability assay; Biology; Cell biology; Inflammation; Medicine; Internal medicine; Endocrinology; Biochemistry; Diabetes mellitus; Tryptophan","score_opus":0.04714354177398092,"score_gpt":0.23201370379654998,"score_spread":0.18487016202256906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982232007","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984643,0.00023809577,0.00009465888,0.000111783185,0.000048647697,0.0003575362,0.000013274093,0.00005389032,0.0006178268],"genre_scores_gemma":[0.9988554,0.000058808033,0.00027734277,0.000103862,0.000022525526,0.00002661465,0.000006108584,0.000018952458,0.00063034653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998746,0.00013364278,0.00037176,0.00021616819,0.0003700273,0.000162443],"domain_scores_gemma":[0.9990827,0.00016320756,0.00023842006,0.00038088363,0.00010868228,0.00002613005],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010617922,0.00011615296,0.00023941603,0.00011626099,0.00005230085,0.000010887209,0.00016162283,0.000069338275,0.00025267756],"category_scores_gemma":[0.00049238635,0.000109534114,0.00006224149,0.00033626778,0.0001818285,0.00039141366,0.00005900364,0.00009491813,0.00006183635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023599499,0.0008620035,0.00024533088,0.00008949332,0.000027262893,3.565843e-7,0.00024431638,0.00002820396,0.99631613,0.00060637906,0.00002587149,0.0013186277],"study_design_scores_gemma":[0.0005178647,0.00016612271,0.21357796,0.00006998496,0.000007328835,3.3728543e-7,0.000055257813,0.0003939486,0.7839675,0.0011492933,0.000010467847,0.00008394524],"about_ca_topic_score_codex":0.000080635655,"about_ca_topic_score_gemma":0.0000016885394,"teacher_disagreement_score":0.21333262,"about_ca_system_score_codex":0.000017430055,"about_ca_system_score_gemma":0.000027048693,"threshold_uncertainty_score":0.44666716},"labels":[],"label_agreement":null},{"id":"W1982809278","doi":"10.1002/jcp.20043","title":"Temperature‐sensitive polymer‐conjugated IFN‐γ induces the expression of IDO mRNA and activity by fibroblasts populated in collagen gel (FPCG)","year":2004,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Peripheral blood mononuclear cell; Northern blot; Western blot; Kynurenine; Chemistry; Molecular biology; Messenger RNA; In vitro; Foreskin; Interferon gamma; Blot; Interferon; Conjugated system; Cell culture; Immunology; Biochemistry; Tryptophan; Biology; Polymer; Gene","score_opus":0.01044905933117303,"score_gpt":0.22995999317648322,"score_spread":0.21951093384531017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982809278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99870354,0.00040387365,0.00001107479,0.00053184456,0.00014201454,0.00013741193,0.000011324031,0.000006983765,0.0000519051],"genre_scores_gemma":[0.99954796,0.000092659415,0.0000145555005,0.00025166036,0.000048486865,0.0000010609003,0.0000017273157,0.000013381104,0.000028534696],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985698,0.0004314251,0.00035011614,0.00022204201,0.0001947156,0.00023194325],"domain_scores_gemma":[0.999057,0.0001987328,0.00047022244,0.00014819227,0.000055176995,0.000070665665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015780644,0.0001659502,0.00037073504,0.00012502419,0.00009366602,0.000018470806,0.00021927377,0.00015955951,0.000014791053],"category_scores_gemma":[0.00017232906,0.00010823404,0.00008393693,0.00031133203,0.0002809162,0.00019447145,0.00007593725,0.0003201302,0.0000015468904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041927156,0.00017203635,0.000018687477,0.000012765974,0.000009183281,0.000032525215,0.00052407815,0.00011319513,0.9983809,0.000033070148,0.00013833898,0.00014596448],"study_design_scores_gemma":[0.0014186392,0.00030012408,0.006331761,0.00008459782,0.000006730136,0.000048036596,0.00020619563,0.000021347305,0.9907269,0.00072846183,0.00001967111,0.000107522115],"about_ca_topic_score_codex":0.00005423892,"about_ca_topic_score_gemma":0.00000800511,"teacher_disagreement_score":0.00765397,"about_ca_system_score_codex":0.000029162024,"about_ca_system_score_gemma":0.00008157076,"threshold_uncertainty_score":0.4413656},"labels":[],"label_agreement":null},{"id":"W1983263255","doi":"10.1182/blood-2006-10-052787","title":"Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":351,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Autocrine signalling; Receptor; Signal transduction; Cell biology; Biology; 5-HT receptor; Serotonin; Immune receptor; Biochemistry","score_opus":0.017783765664830826,"score_gpt":0.2671376262674251,"score_spread":0.24935386060259426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983263255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99267673,0.00005651024,0.0020081075,0.00077874004,0.0000737821,0.0005974143,0.0000159528,0.00013763104,0.0036551098],"genre_scores_gemma":[0.9964123,0.000005353883,0.0005266239,0.0018357943,0.00016544765,0.00011368624,0.000008869077,0.000027347425,0.00090462837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855727,0.00015517796,0.00019864418,0.00047277322,0.00029967102,0.00031645913],"domain_scores_gemma":[0.99929464,0.0002636503,0.0001052297,0.00025851573,0.000027422004,0.000050545303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011407319,0.00016562933,0.000110536144,0.000030654344,0.00028280308,0.0001678176,0.00045584465,0.00006367702,0.00016857187],"category_scores_gemma":[0.00010803015,0.00012653686,0.00004452378,0.00033890657,0.000072922696,0.00053838507,0.000053447533,0.00015275067,0.00010661423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025657715,0.0005156981,0.00006410062,0.00001226714,0.0000016608623,8.258937e-7,0.0003550948,0.00015172176,0.9951543,0.00026351475,0.002608417,0.0008467498],"study_design_scores_gemma":[0.00038091643,0.00013781889,0.000093699826,0.000016814669,0.0000053522617,0.0000010058548,0.00014088664,0.000022338516,0.98975295,0.00096292945,0.008300406,0.00018488916],"about_ca_topic_score_codex":0.00009717782,"about_ca_topic_score_gemma":0.000009879632,"teacher_disagreement_score":0.005691989,"about_ca_system_score_codex":0.000016205691,"about_ca_system_score_gemma":0.000041541316,"threshold_uncertainty_score":0.51600236},"labels":[],"label_agreement":null},{"id":"W1984103995","doi":"10.1016/j.bbi.2014.05.007","title":"Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides","year":2014,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":545,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Priming (agriculture); White matter; Anterior cingulate cortex; Microglia; Dorsum; Neuroscience; Psychology; Medicine; Internal medicine; Biology; Anatomy; Cognition; Inflammation; Magnetic resonance imaging","score_opus":0.09350439338302426,"score_gpt":0.333597160137663,"score_spread":0.24009276675463875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984103995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981908,0.00028715556,0.00009812297,0.00032939808,0.00005351357,0.00096247316,0.000025393234,0.000013822747,0.000039310788],"genre_scores_gemma":[0.9984456,0.000044895467,0.00022204463,0.0010828548,0.000012696393,0.000130543,0.0000023803238,0.000013665757,0.00004535917],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99865085,0.00046377105,0.0002660916,0.00026139253,0.00012143227,0.00023644665],"domain_scores_gemma":[0.9985092,0.0010391963,0.00010552348,0.00028995477,0.000019390014,0.0000367069],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073228194,0.0001492456,0.00020772379,0.00008003818,0.0001858347,0.000080610975,0.00026065722,0.000059344933,0.00002414351],"category_scores_gemma":[0.0005921496,0.00011284119,0.000050665993,0.000105459265,0.00025084472,0.0001616674,0.000114397546,0.00014712875,0.000001024388],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017087972,0.000111862675,0.08342199,0.000070597496,0.0000012799205,0.0000036956656,0.0016448448,3.1262493e-7,0.9031688,0.000017017548,0.00002815774,0.0113605745],"study_design_scores_gemma":[0.001046447,0.00014125761,0.784994,0.00012209064,0.000017128892,0.000023609611,0.0002493979,0.000046598172,0.21310467,0.000062084066,0.000073063995,0.00011966028],"about_ca_topic_score_codex":0.0003776836,"about_ca_topic_score_gemma":0.000057161113,"teacher_disagreement_score":0.701572,"about_ca_system_score_codex":0.000010456797,"about_ca_system_score_gemma":0.000014992307,"threshold_uncertainty_score":0.460153},"labels":[],"label_agreement":null},{"id":"W1985438873","doi":"10.1016/j.biopsych.2009.09.033","title":"A Meta-Analysis of Cytokines in Major Depression","year":2009,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4711,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Physicians' Services Incorporated Foundation; Heart and Stroke Foundation of Canada","keywords":"Depression (economics); Meta-analysis; Medicine; Psychology; Internal medicine; Economics","score_opus":0.2356003050753093,"score_gpt":0.3830227688152376,"score_spread":0.14742246373992832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985438873","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015892705,0.9975677,0.000010975541,0.00007495162,0.00017053272,0.000425509,0.00012184726,0.00004862534,0.0014209135],"genre_scores_gemma":[0.00087408785,0.99803025,0.00033097825,0.00051509624,0.00004895626,0.000056809116,0.000034412806,0.000012808946,0.000096575684],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99712616,0.00062277395,0.00088711455,0.0008606138,0.00020443724,0.00029886948],"domain_scores_gemma":[0.9984925,0.00041744404,0.0004996246,0.00050973374,0.0000106634925,0.00007007824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022266987,0.00041631152,0.0037421307,0.00062518474,0.000036467765,0.000015948815,0.0006911711,0.000528797,0.00055715535],"category_scores_gemma":[0.00024206543,0.00021629945,0.003760933,0.0023571735,0.00012429673,0.000032302898,0.00009602507,0.00033643027,0.0000357344],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013371093,0.003062371,0.00084728515,0.0047621974,0.045007445,0.000046478814,0.000035337995,0.000016801136,0.00022209394,0.008197742,0.0021408782,0.9355277],"study_design_scores_gemma":[0.00045275397,0.00024846446,0.0016691324,0.0005267921,0.1765664,0.000012761691,0.000012895604,0.0000069796065,0.000027277472,0.00363175,0.8158334,0.0010113929],"about_ca_topic_score_codex":0.0000075603753,"about_ca_topic_score_gemma":0.000025842868,"teacher_disagreement_score":0.93451625,"about_ca_system_score_codex":0.000014297433,"about_ca_system_score_gemma":0.000062868225,"threshold_uncertainty_score":0.8820436},"labels":[],"label_agreement":null},{"id":"W1986031990","doi":"10.1080/10401230701653377","title":"Should Depressive Syndromes Be Reclassified as “Metabolic Syndrome Type II”?","year":2007,"lang":"en","type":"review","venue":"Annals of Clinical Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":280,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Metabolic syndrome; Comorbidity; Mood disorders; Hypermetabolism; Bioinformatics; Diabetes mellitus; Disease; Medicine; Type 2 diabetes; Neuroscience; Psychology; Internal medicine; Psychiatry; Endocrinology; Biology; Anxiety","score_opus":0.542984936507987,"score_gpt":0.5387917777331586,"score_spread":0.004193158774828398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986031990","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021025066,0.96939373,0.0000032750786,0.001703785,0.0068447776,0.0009292631,0.00013016463,0.00016950835,0.018722966],"genre_scores_gemma":[0.0008215317,0.9862222,0.0001929298,0.009409663,0.0005454897,0.000028147333,0.000035222452,0.0001529338,0.0025918852],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9917619,0.0010184181,0.0036473896,0.0016454278,0.0009935461,0.00093330373],"domain_scores_gemma":[0.9924062,0.0030304925,0.0022519166,0.0015848817,0.00016463679,0.0005618767],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0016538111,0.0008824983,0.004673342,0.00050654134,0.00023232888,0.0000563275,0.0018664302,0.0013987671,0.00084072904],"category_scores_gemma":[0.0063448222,0.0007063861,0.002693035,0.001581224,0.0007705607,0.00020942673,0.00046662166,0.002007129,0.0006506344],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000153574,0.0015168773,0.00009380534,0.004882135,0.00037705537,0.00017757314,0.000018821189,4.9313604e-7,0.0000014450925,0.011386866,0.053088803,0.9283025],"study_design_scores_gemma":[0.0004903104,0.0007680597,0.0003370082,0.004481258,0.00029534308,0.0003168448,0.0000139495305,7.2750976e-7,0.00002126514,0.0035359177,0.98900926,0.00073003443],"about_ca_topic_score_codex":0.0000150981605,"about_ca_topic_score_gemma":0.000009037077,"teacher_disagreement_score":0.9359205,"about_ca_system_score_codex":0.000006648934,"about_ca_system_score_gemma":0.0012522659,"threshold_uncertainty_score":0.9998976},"labels":[],"label_agreement":null},{"id":"W1986876625","doi":"10.1097/fbp.0b013e32834d1385","title":"Pretreatment with pentoxifylline has antidepressant-like effects in a rat model of acute myocardial infarction","year":2011,"lang":"en","type":"article","venue":"Behavioural Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Pentoxifylline; Medicine; Behavioural despair test; Saline; Myocardial infarction; Internal medicine; Endocrinology; Ischemia; Anesthesia; Antidepressant; Hippocampus","score_opus":0.06719692729588522,"score_gpt":0.2945393444713391,"score_spread":0.2273424171754539,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986876625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99802977,0.00003430271,0.00026935068,0.000095552314,0.00046430953,0.0007484455,0.000026198364,0.000059593218,0.00027244954],"genre_scores_gemma":[0.9987005,0.00006220309,0.00045162567,0.000489296,0.000018018274,0.00012081913,0.000008520533,0.00002229772,0.00012670393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998658,0.00017600668,0.00023829738,0.00039190557,0.00018174508,0.0003540244],"domain_scores_gemma":[0.99955434,0.00006042054,0.00012325401,0.00014924249,0.0000248586,0.000087881635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000067624795,0.00020424231,0.00028524068,0.00016845245,0.00006469288,0.000010212817,0.00020394936,0.000087564775,0.0001464865],"category_scores_gemma":[0.000008259158,0.00016536884,0.000078645186,0.00021080443,0.0002743854,0.0002015467,0.00007368867,0.0001899246,0.00001862611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014520235,0.00082262175,0.04921301,0.000017321543,0.000040538704,0.00016306686,0.0007219534,0.0003723403,0.9459493,0.00008284858,0.00069140346,0.0004735459],"study_design_scores_gemma":[0.005091706,0.00082648813,0.05482566,0.000013656722,0.00021202816,0.00004168009,0.000015571926,0.0029576432,0.9356475,0.0001252968,0.00002826623,0.00021453039],"about_ca_topic_score_codex":0.0001792695,"about_ca_topic_score_gemma":0.000038951595,"teacher_disagreement_score":0.01030185,"about_ca_system_score_codex":0.000047520844,"about_ca_system_score_gemma":0.00006617158,"threshold_uncertainty_score":0.67435455},"labels":[],"label_agreement":null},{"id":"W1987469263","doi":"10.1016/j.neuroscience.2010.08.060","title":"A developmental characterization of mesolimbocortical serotonergic gene expression changes following early immune challenge","year":2010,"lang":"en","type":"article","venue":"Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Calgary; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"TPH2; Serotonergic; Amygdala; Dorsal raphe nucleus; 5-HT receptor; Endocrinology; Forebrain; Internal medicine; Hippocampus; Serotonin transporter; Neuroscience; Serotonin; Tryptophan hydroxylase; Psychology; Receptor; Basolateral amygdala; Biology; Central nervous system; Medicine","score_opus":0.02746411325578932,"score_gpt":0.25675125316240544,"score_spread":0.22928713990661612,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987469263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99769753,0.0000051847433,0.0002267048,0.00028069128,0.0008349963,0.00032107174,0.0000082698425,0.000095444644,0.0005301301],"genre_scores_gemma":[0.99894375,0.000033177337,0.00035001125,0.0004215535,0.000041614876,0.000044723925,0.0000014921008,0.000020470834,0.00014318358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981978,0.00006480126,0.00025729457,0.0005716291,0.0005205958,0.0003878907],"domain_scores_gemma":[0.9994331,0.00005836456,0.00014144987,0.00022190175,0.000020797457,0.00012437347],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001408929,0.00017332048,0.00018823927,0.000132943,0.00022948474,0.00005878429,0.0005406417,0.000082380364,0.00004056215],"category_scores_gemma":[0.00043706057,0.0001550447,0.00007260536,0.00049269554,0.000262691,0.00037112652,0.00019966181,0.00022788269,0.000018550734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015643574,0.00012069628,0.00079343823,0.0000079685915,3.0018353e-7,0.000016217253,0.00037247813,5.5227673e-7,0.9970301,0.000312602,0.0000010627313,0.0013289604],"study_design_scores_gemma":[0.00028076346,0.00010566799,0.09856541,0.000015781883,0.0000017351728,0.00001621004,0.000014507767,0.00016191823,0.900253,0.000042599437,0.000393587,0.00014880496],"about_ca_topic_score_codex":0.0000043929094,"about_ca_topic_score_gemma":0.0000040008135,"teacher_disagreement_score":0.097771965,"about_ca_system_score_codex":0.000009912003,"about_ca_system_score_gemma":0.0000612751,"threshold_uncertainty_score":0.63225394},"labels":[],"label_agreement":null},{"id":"W1987482349","doi":"10.1186/1471-2458-9-s1-s12","title":"Reconciling conflicting clinical studies of antioxidant supplementation as HIV therapy: a mathematical approach","year":2009,"lang":"en","type":"article","venue":"BMC Public Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Medicine; Antioxidant; Reactive oxygen species; Immunology; Human immunodeficiency virus (HIV); Immunosuppression; Biostatistics; Apoptosis; Internal medicine; Epidemiology; Biology; Cell biology; Biochemistry","score_opus":0.3072628626192817,"score_gpt":0.46370722915790363,"score_spread":0.15644436653862193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987482349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9791727,0.0002983326,0.0074708275,0.007606317,0.00011875852,0.0006738848,0.0000109594575,0.00012046736,0.004527738],"genre_scores_gemma":[0.98536706,0.0006847982,0.008198809,0.00548361,0.000085355605,0.000015024604,0.000005768593,0.000012074342,0.00014751912],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9972644,0.00061639125,0.0009289183,0.00040513618,0.00035188877,0.0004332613],"domain_scores_gemma":[0.99828774,0.0008526096,0.00036735233,0.00024590554,0.000068436566,0.00017796898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002695497,0.00013605462,0.0004109078,0.00010927146,0.00017266873,0.000049120034,0.00020878449,0.000054860677,0.00006465279],"category_scores_gemma":[0.0032635995,0.000110304456,0.00010945903,0.00032876013,0.000156116,0.0002050394,0.000031421117,0.00017347238,0.000023265939],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040813262,0.0074751684,0.028378105,0.0015108776,0.000112340465,0.000010094839,0.04210106,0.00004243675,0.02758167,0.41222757,0.010123718,0.47002885],"study_design_scores_gemma":[0.062004328,0.01964333,0.31008267,0.001448976,0.00006180383,0.0006376784,0.21762472,0.051809024,0.0936554,0.12416187,0.113688126,0.0051820553],"about_ca_topic_score_codex":0.000007807605,"about_ca_topic_score_gemma":0.0000028337295,"teacher_disagreement_score":0.4648468,"about_ca_system_score_codex":0.00005429823,"about_ca_system_score_gemma":0.00049429585,"threshold_uncertainty_score":0.4498085},"labels":[],"label_agreement":null},{"id":"W1987906603","doi":"10.1016/j.neuroscience.2005.03.051","title":"The pathogenesis of clinical depression: Stressor- and cytokine-induced alterations of neuroplasticity","year":2005,"lang":"en","type":"review","venue":"Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":324,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neuroplasticity; Stressor; Neuroscience; Depression (economics); Pathogenesis; Psychology; Cytokine; Medicine; Internal medicine","score_opus":0.17701686337523118,"score_gpt":0.41751406098642097,"score_spread":0.2404971976111898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987906603","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03330679,0.9612408,0.00013888063,0.0001042555,0.0024685988,0.0014165409,0.00037297542,0.00008841637,0.0008627236],"genre_scores_gemma":[0.048764978,0.950822,0.00003653675,0.00015275831,0.00009713928,0.000024371531,7.2133014e-7,0.000025870635,0.0000756379],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961417,0.00082929956,0.0012335276,0.000891217,0.00057283096,0.00033146158],"domain_scores_gemma":[0.9948748,0.0033181598,0.0009066284,0.0006980325,0.000053571155,0.00014884518],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041157156,0.0003122692,0.0009698604,0.000115867166,0.00036494678,0.000075601056,0.0010355115,0.00015352177,0.0000060802945],"category_scores_gemma":[0.006270305,0.0001937007,0.0003177449,0.0007583948,0.0010024532,0.00014842444,0.0003731694,0.000413676,0.000003853588],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008955233,0.00013138425,0.00009586513,0.0005283343,0.0000014719442,0.000010353531,0.00001376753,0.0000070786864,0.010158035,0.00034067163,0.000048239155,0.98865587],"study_design_scores_gemma":[0.00047338818,0.00037675689,0.009237537,0.0017242284,0.00015349047,0.0001403435,0.00001046807,0.000660001,0.0053381687,0.000036706886,0.9813141,0.00053478096],"about_ca_topic_score_codex":0.0000026141042,"about_ca_topic_score_gemma":0.000005690563,"teacher_disagreement_score":0.9881211,"about_ca_system_score_codex":0.000006256568,"about_ca_system_score_gemma":0.00028437813,"threshold_uncertainty_score":0.78988856},"labels":[],"label_agreement":null},{"id":"W1988502754","doi":"10.1016/j.neuropharm.2011.11.022","title":"A stereological comparison of GAD67 and reelin expression in the hippocampal stratum oriens of offspring from two mouse models of maternal inflammation during pregnancy","year":2011,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":92,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Reelin; Offspring; Glutamate decarboxylase; DAB1; Hippocampal formation; Hippocampus; Endocrinology; Internal medicine; Biology; Neuroscience; Pregnancy; Medicine; Genetics","score_opus":0.07371341411499724,"score_gpt":0.3053287581327212,"score_spread":0.23161534401772396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988502754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99922943,0.00007330826,0.000079021,0.000018881998,0.00010732175,0.00026694036,0.000013886879,0.000014574113,0.00019664211],"genre_scores_gemma":[0.9996558,0.00007677001,0.00020067037,0.000023726292,0.000017295926,0.000010308211,6.032859e-7,0.0000087879225,0.0000060574557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99848527,0.0004347458,0.0004758925,0.00025824388,0.00016972792,0.00017612072],"domain_scores_gemma":[0.99924165,0.00023423567,0.0003091395,0.00015906179,0.000024434197,0.000031471543],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000068280584,0.00011455156,0.0002604017,0.00009473258,0.00003083317,0.000004499382,0.00029697613,0.000059765734,0.000057631132],"category_scores_gemma":[0.00007423197,0.000085819345,0.00003584714,0.00012122794,0.00022355118,0.00013471754,0.00013206432,0.0002077987,7.684461e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004438352,0.0001450073,0.020618612,0.000059412545,0.0000024600301,0.000027257736,0.003395654,0.00039049523,0.9739284,0.00026472137,0.000001648546,0.0007225157],"study_design_scores_gemma":[0.0013878499,0.00016021136,0.09657849,0.00004883774,0.0000075572098,0.0000051610955,0.00016594435,0.0034950043,0.89750326,0.0005887728,0.0000010038141,0.000057930687],"about_ca_topic_score_codex":0.000047943842,"about_ca_topic_score_gemma":0.000012666636,"teacher_disagreement_score":0.07642514,"about_ca_system_score_codex":0.000005005618,"about_ca_system_score_gemma":0.000014350973,"threshold_uncertainty_score":0.34996113},"labels":[],"label_agreement":null},{"id":"W1988788559","doi":"10.1016/j.bbi.2009.12.001","title":"Interferon-gamma deficiency modifies the effects of a chronic stressor in mice: Implications for psychological pathology","year":2009,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Neurochemical; Corticosterone; Amygdala; Endocrinology; Internal medicine; Psychology; Serotonergic; Elevated plus maze; Cytokine; Neuroscience; Medicine; Anxiety; Serotonin; Hormone; Psychiatry; Receptor","score_opus":0.03683791107311605,"score_gpt":0.33568801719736713,"score_spread":0.29885010612425106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988788559","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99695706,0.0004243582,0.0002018677,0.0013987301,0.00007577539,0.0007399745,0.000019671748,0.000025626528,0.0001569127],"genre_scores_gemma":[0.99912417,0.00011962398,0.00003581164,0.0004939494,0.000009754057,0.00016691552,0.0000038787107,0.0000056597964,0.00004026046],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99905014,0.00020794547,0.00020735759,0.00024135763,0.00005286265,0.00024030816],"domain_scores_gemma":[0.998786,0.00079979264,0.00007060489,0.00029604242,0.000017997241,0.000029611885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016236334,0.00011628722,0.00015788327,0.00007273668,0.00017337537,0.000020582165,0.00034860027,0.000084842635,0.000007191654],"category_scores_gemma":[0.00062888325,0.00008215741,0.000060810667,0.00019363407,0.000329796,0.00006780214,0.000053270458,0.00019744252,0.0000013094458],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048759415,0.00079463643,0.00083125045,0.000023855628,4.4054443e-7,0.00000189362,0.00052420265,0.0000010048238,0.9159917,0.0032175176,0.00010078856,0.07846391],"study_design_scores_gemma":[0.0011134187,0.0015096384,0.9221578,0.000023462975,0.000009392866,0.000030005403,0.00015444843,0.000017870847,0.07201199,0.0028024132,0.00005107838,0.000118446274],"about_ca_topic_score_codex":0.000015970314,"about_ca_topic_score_gemma":0.000025313995,"teacher_disagreement_score":0.9213266,"about_ca_system_score_codex":0.00001866927,"about_ca_system_score_gemma":0.000016790576,"threshold_uncertainty_score":0.33502817},"labels":[],"label_agreement":null},{"id":"W1989730770","doi":"10.1080/17450390903217465","title":"Tryptophan metabolism and related B vitamins in the multiparous sow fed<i>ad libitum</i>after farrowing","year":2009,"lang":"en","type":"article","venue":"Archives of Animal Nutrition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Lactation; Niacin; Endocrinology; Tryptophan; Internal medicine; Haptoglobin; Animal science; Weaning; Biology; Kynurenine; Chemistry; Pregnancy; Amino acid; Medicine; Biochemistry","score_opus":0.012078167008924504,"score_gpt":0.2379719202829054,"score_spread":0.2258937532739809,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989730770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951166,0.0009982022,0.000036990652,0.0018786856,0.000035297926,0.00033316936,0.000015489524,0.00003844063,0.0015471597],"genre_scores_gemma":[0.9981613,0.00042113214,0.00045662743,0.00088388583,0.00002559417,0.000019003432,0.0000043221457,0.0000097961365,0.00001829822],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988469,0.00019202293,0.00025099856,0.00031292328,0.00014971431,0.00024747793],"domain_scores_gemma":[0.9994366,0.0002900687,0.00006854687,0.00015467477,0.0000057305474,0.000044367916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000805087,0.00014590207,0.00018223202,0.00016989681,0.0000921123,0.000041432268,0.00019500677,0.00004935944,0.00000685936],"category_scores_gemma":[0.00012413738,0.00011343893,0.00008887891,0.0002529251,0.00019397055,0.00024956817,0.000029509729,0.00019688791,0.000004112341],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054893846,0.00048238435,0.00006759785,0.000028743822,0.0000024091162,0.000032848286,0.0037021036,8.9567897e-7,0.9814722,0.0022915257,0.000023193219,0.01134718],"study_design_scores_gemma":[0.004890809,0.0012823151,0.5731254,0.00023867442,0.00001771111,0.000107505155,0.0014483915,0.0010762159,0.37348968,0.042692352,0.0012309428,0.0003999679],"about_ca_topic_score_codex":0.000008870124,"about_ca_topic_score_gemma":0.000008692174,"teacher_disagreement_score":0.6079825,"about_ca_system_score_codex":0.000003885081,"about_ca_system_score_gemma":0.000008038803,"threshold_uncertainty_score":0.46259055},"labels":[],"label_agreement":null},{"id":"W1989787131","doi":"10.1016/j.bbi.2009.04.010","title":"Does the nature of neonatal host anti-viral immunity control adult brain function?","year":2009,"lang":"en","type":"letter","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Immunity; Brain function; Host (biology); Function (biology); Virology; Biology; Immunology; Immune system; Neuroscience; Evolutionary biology; Genetics","score_opus":0.008985375275151445,"score_gpt":0.24504503623022866,"score_spread":0.23605966095507722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989787131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6807292,0.0005345157,0.000035466204,0.31422347,0.0013347958,0.0013299545,0.0011714464,0.00016581334,0.000475343],"genre_scores_gemma":[0.6030954,0.00008751394,0.000009680849,0.3945407,0.00039716385,0.0000486865,0.00016731466,0.000051952273,0.001601553],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.995821,0.0015172127,0.0006166664,0.00067473087,0.0006772427,0.00069316995],"domain_scores_gemma":[0.99611694,0.0017701878,0.00046129912,0.0013964691,0.00016766874,0.00008746171],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0004825227,0.00068709557,0.00075502356,0.00023311825,0.0010400864,0.00020191459,0.0013464809,0.0014181959,0.00023915268],"category_scores_gemma":[0.001388855,0.00040414807,0.00041076064,0.00039988582,0.0011876946,0.0003284356,0.00025578708,0.006622652,0.000015086684],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039913796,0.00064888335,0.0019179712,0.0002229999,0.00007790147,0.00023556441,0.0012052334,7.917989e-7,0.1963599,0.00052137615,0.7616702,0.036740087],"study_design_scores_gemma":[0.005639282,0.0010202357,0.52604914,0.0002347355,0.00036599205,0.00022010352,0.0013828209,0.000015162601,0.026283562,0.0009467689,0.4360814,0.0017607664],"about_ca_topic_score_codex":0.00049330015,"about_ca_topic_score_gemma":0.00006820226,"teacher_disagreement_score":0.5241312,"about_ca_system_score_codex":0.000033095133,"about_ca_system_score_gemma":0.00012138077,"threshold_uncertainty_score":0.99987817},"labels":[],"label_agreement":null},{"id":"W1991262780","doi":"10.1111/j.1399-5618.2009.00717.x","title":"Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia","year":2009,"lang":"en","type":"article","venue":"Bipolar Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":269,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Oxidative stress; Bipolar disorder; Schizophrenia (object-oriented programming); Internal medicine; Lipid peroxidation; Neuropathology; Anterior cingulate cortex; DISC1; 4-Hydroxynonenal; Major depressive disorder; Pathological; Medicine; Psychology; Endocrinology; Psychiatry; Chemistry; Lithium (medication); Biochemistry; Cognition; Amygdala; Disease","score_opus":0.007948296916359168,"score_gpt":0.22732051591360608,"score_spread":0.2193722189972469,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991262780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905741,0.007920248,0.00009600193,0.00046356433,0.00003333352,0.00060681446,0.00005020567,0.000053610955,0.00020211276],"genre_scores_gemma":[0.9969527,0.00232944,0.00011030144,0.0005322303,0.000013711549,0.000013985124,0.000006893866,0.000024940467,0.000015770847],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99802345,0.00031133895,0.00031309648,0.0005290054,0.0003874886,0.00043563725],"domain_scores_gemma":[0.99904263,0.000258347,0.00018312004,0.0004095106,0.000024313518,0.000082059894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000208111,0.0003046228,0.0003229634,0.00026856048,0.00017895238,0.00006941828,0.000456089,0.000087305205,0.00002514263],"category_scores_gemma":[0.00025325533,0.00020893462,0.00006863633,0.0009205891,0.00043965888,0.0002758071,0.00004805758,0.00026857635,0.00000472458],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018988309,0.0019067024,0.20092036,0.00014857334,0.000042573425,0.000048928643,0.006778496,0.000061765095,0.5650052,0.0041492847,0.000048453636,0.21899088],"study_design_scores_gemma":[0.0044616275,0.00093971926,0.9527184,0.0001723175,0.00002720439,0.0000212418,0.0018205617,0.00033724576,0.03416631,0.0011444081,0.003660329,0.000530654],"about_ca_topic_score_codex":0.00059701677,"about_ca_topic_score_gemma":0.0026426066,"teacher_disagreement_score":0.75179803,"about_ca_system_score_codex":0.000012724293,"about_ca_system_score_gemma":0.00006530772,"threshold_uncertainty_score":0.85201067},"labels":[],"label_agreement":null},{"id":"W1992628789","doi":"10.1007/s12529-010-9078-9","title":"Depressive Symptoms and C-Reactive Protein Are Not Associated in a Population-Based Sample of Adolescents","year":2010,"lang":"en","type":"article","venue":"International Journal of Behavioral Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Centre Hospitalier de l’Université de Montréal; Université de Montréal; Institut National de Santé Publique du Québec; University of Toronto","funders":"","keywords":"Depression (economics); Medicine; C-reactive protein; Body mass index; National Health and Nutrition Examination Survey; Odds ratio; Confidence interval; Internal medicine; Anthropometry; Blood pressure; Percentile; Population; Demography; Inflammation; Environmental health","score_opus":0.02745312320797543,"score_gpt":0.32669142564369286,"score_spread":0.2992383024357174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992628789","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99856025,0.000009961405,0.000053127853,0.0007373615,0.00045100358,0.00013937922,0.00003531473,0.000005557177,0.000008054851],"genre_scores_gemma":[0.99959683,0.0000013502029,0.00006292674,0.00023466258,0.00008153856,0.0000036350227,0.0000046758146,0.000008397915,0.0000059501417],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986749,0.0000626142,0.00041829987,0.0001254458,0.0006171016,0.000101592785],"domain_scores_gemma":[0.9987576,0.00016825486,0.0006899339,0.000062212275,0.00025125992,0.00007072385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016250566,0.00009359384,0.00021441745,0.00030153728,0.000018540097,0.000011051357,0.00024176748,0.000063229745,0.00005437439],"category_scores_gemma":[0.0016149158,0.00007438669,0.000043244643,0.00012365362,0.00012274101,0.0001555216,0.000024850491,0.000330696,3.990424e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001882994,0.00032824202,0.51409924,0.000003972683,0.000004899393,0.000052040814,0.00016830201,0.0000065111444,0.48299545,0.000068090325,0.0000063001626,0.0020786526],"study_design_scores_gemma":[0.0030545106,0.00021058891,0.895818,0.00063831074,0.0000122854335,0.000019070954,0.00007343532,0.00008166422,0.099661954,0.0003543302,0.000008680143,0.000067182045],"about_ca_topic_score_codex":0.0005707203,"about_ca_topic_score_gemma":0.00033165858,"teacher_disagreement_score":0.3833335,"about_ca_system_score_codex":0.000051513616,"about_ca_system_score_gemma":0.000045250436,"threshold_uncertainty_score":0.3033401},"labels":[],"label_agreement":null},{"id":"W1993000695","doi":"10.1177/0269881108091077","title":"Effects of bupropion augmentation on pro-inflammatory cytokines in escitalopram-resistant patients with major depressive disorder","year":2008,"lang":"en","type":"article","venue":"Journal of Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Eesti Teadusfondi","keywords":"Bupropion; Escitalopram; Major depressive disorder; Medicine; Pharmacology; Psychiatry; Psychology; Antidepressant; Mood; Anxiety; Smoking cessation","score_opus":0.009006476727296842,"score_gpt":0.2675902398947552,"score_spread":0.2585837631674584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993000695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99841446,0.00012563364,0.000054656455,0.00014483008,0.0006161619,0.00051730697,0.0000039002302,0.000009218296,0.00011384083],"genre_scores_gemma":[0.9992352,0.00012530481,0.00008839669,0.00042001158,0.000059964008,0.000020781743,7.1852276e-7,0.00001853955,0.000031091102],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998506,0.00022077285,0.00046571778,0.00020915038,0.00038454143,0.00021379508],"domain_scores_gemma":[0.9988063,0.00029684225,0.00063282636,0.00008245582,0.00010636213,0.00007522242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008018982,0.0001572721,0.0002662193,0.0003480187,0.00007122102,0.00000642333,0.00021266387,0.00006635004,0.000044514723],"category_scores_gemma":[0.00014534619,0.00011419604,0.00006901209,0.0002949982,0.00017536107,0.00022443452,0.000018195331,0.0002501445,0.0000060197954],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0104094995,0.0018439229,0.0726119,0.00015284544,0.000039312243,0.0004024482,0.00073228934,0.0003268918,0.91056067,0.000058433405,0.00094365515,0.0019181089],"study_design_scores_gemma":[0.020640075,0.0019042654,0.6779411,0.000111365625,0.000027169252,0.000026600908,0.000035599733,0.000020041301,0.2987399,0.00014808709,0.00025151597,0.00015427425],"about_ca_topic_score_codex":0.000004291215,"about_ca_topic_score_gemma":0.0000072074645,"teacher_disagreement_score":0.61182076,"about_ca_system_score_codex":0.00005204776,"about_ca_system_score_gemma":0.000073466974,"threshold_uncertainty_score":0.46567792},"labels":[],"label_agreement":null},{"id":"W1993820575","doi":"10.1016/j.jaci.2007.12.1039","title":"In Vivo Inhibition Of Indoleamine 2, 3 - Dioxygenase (IDO) Prevents Ovalbumin-Induced Tolerance","year":2008,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Ovalbumin; Mechanism (biology); In vivo; Antigen; Immune tolerance; Immunotherapy; Immunology; Cancer research; Immune system; Catabolism; Biology; Medicine; Enzyme; Tryptophan; Genetics","score_opus":0.042598747132014,"score_gpt":0.31225088909419507,"score_spread":0.26965214196218107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993820575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998343,0.0004483349,0.000020797004,0.00041116407,0.00044109,0.00006548425,0.0000019287595,0.000004489909,0.00026372945],"genre_scores_gemma":[0.99406475,0.004961607,0.00006951666,0.0006100411,0.00008909148,0.0000011409763,1.9812268e-7,0.0000079605825,0.00019568526],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814725,0.00031696513,0.0010105517,0.000185579,0.00015393915,0.0001857229],"domain_scores_gemma":[0.99876815,0.00043346698,0.00055099954,0.00013352255,0.000052619776,0.000061239574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030520515,0.00011123836,0.00042273264,0.00014066709,0.00004859802,0.0000040220366,0.00017199184,0.00019048729,0.00010311856],"category_scores_gemma":[0.00081016234,0.000093800365,0.00014425356,0.00018669506,0.0003713786,0.00022197946,0.00006359973,0.00046470857,0.0000043936448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014054395,0.0013771903,0.0008494009,0.000009134424,0.000084120744,0.0003858032,0.00030581033,0.00001372131,0.9916556,0.0004020747,0.00041052912,0.003101199],"study_design_scores_gemma":[0.007768285,0.0023967135,0.14073685,0.00013342568,0.0000055118376,0.0006804483,0.00012906129,0.000036415513,0.84392804,0.0014624486,0.002533189,0.00018963536],"about_ca_topic_score_codex":0.000010837467,"about_ca_topic_score_gemma":0.000021200405,"teacher_disagreement_score":0.14772756,"about_ca_system_score_codex":0.000012765655,"about_ca_system_score_gemma":0.00007606511,"threshold_uncertainty_score":0.3825068},"labels":[],"label_agreement":null},{"id":"W1995493368","doi":"10.1371/journal.pone.0047581","title":"Molecular Pathway Reconstruction and Analysis of Disturbed Gene Expression in Depressed Individuals Who Died by Suicide","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Carleton University; Western University","funders":"Robarts Research Institute; Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Microarray analysis techniques; Gene expression; Microarray; Gene; Biology; Gene expression profiling; Major depressive disorder; Bioinformatics; Neuroscience; Genetics; Cognition","score_opus":0.03366294106427725,"score_gpt":0.2365250249419277,"score_spread":0.20286208387765045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995493368","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987554,0.0005560251,0.00015271755,0.000037241556,0.00001449326,0.00016539004,0.00007045407,0.000022438488,0.00022586524],"genre_scores_gemma":[0.99912393,0.00009409694,0.0006104641,0.00009475316,0.0000074243485,0.000019109302,0.000017416885,0.000010280577,0.000022494776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891984,0.00014349753,0.00021934156,0.00024693526,0.00025738156,0.00021298794],"domain_scores_gemma":[0.9994725,0.00012071245,0.00011845202,0.00019713142,0.000013728657,0.00007745503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012147873,0.00010283764,0.00028406925,0.00022392762,0.00003632843,0.000016085089,0.000103699975,0.00006536732,0.000036832982],"category_scores_gemma":[0.00030980387,0.000095836665,0.000043994307,0.00056136627,0.0000850508,0.00018556669,0.000057392062,0.00008195045,0.0000015624942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015388081,0.00042074654,0.16011485,0.000016957963,0.000051251052,7.154044e-7,0.00027026015,0.000006986365,0.83827925,0.00002282899,0.0000054742463,0.0007952634],"study_design_scores_gemma":[0.00036114428,0.000016819551,0.114278026,0.00004209683,0.00008873149,3.9668615e-7,0.000038129434,0.0002478738,0.884767,0.000060915467,0.0000031662198,0.00009571332],"about_ca_topic_score_codex":0.000016870488,"about_ca_topic_score_gemma":0.0000058177943,"teacher_disagreement_score":0.046487708,"about_ca_system_score_codex":0.000012098116,"about_ca_system_score_gemma":0.000006549076,"threshold_uncertainty_score":0.39081058},"labels":[],"label_agreement":null},{"id":"W1996300729","doi":"10.1016/j.psyneuen.2010.09.006","title":"Alterations in cognitive function and behavioral response to amphetamine induced by prenatal inflammation are dependent on the stage of pregnancy","year":2010,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Canadian Bureau for International Education","keywords":"Offspring; Prepulse inhibition; Pregnancy; Amphetamine; Gestation; Endocrinology; Internal medicine; Methamphetamine; Nucleus accumbens; Medicine; Psychology; Dopamine; Physiology; Schizophrenia (object-oriented programming); Biology; Psychiatry","score_opus":0.04269450897734834,"score_gpt":0.31381725807198474,"score_spread":0.2711227490946364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996300729","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99593395,0.000013069439,0.00006594262,0.0026504707,0.00040640225,0.0006506588,0.00008613987,0.00003160629,0.00016177562],"genre_scores_gemma":[0.99899715,0.000011488414,0.000007632595,0.0004576257,0.0000136599365,0.00014130889,0.0000042452934,0.000012485568,0.0003544124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872464,0.0002982369,0.00023100841,0.0003855757,0.000134443,0.00022606822],"domain_scores_gemma":[0.99916327,0.00041312038,0.00011854911,0.00022750179,0.000028607403,0.000048949674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000050100494,0.00012636426,0.0001224492,0.00018724658,0.00008105153,0.000023244002,0.00013772777,0.000037219033,0.00006994126],"category_scores_gemma":[0.0007026928,0.000106414416,0.000021655582,0.00021970215,0.0001095176,0.00010963012,0.00005125625,0.00032338058,0.000019185467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011584826,0.00023157081,0.0020507583,0.0000064026563,0.0000020744262,0.000016551092,0.00028701287,0.000002601218,0.99161655,0.0011731369,0.00004277668,0.0034120874],"study_design_scores_gemma":[0.0018464839,0.0010732723,0.18714245,0.000051853254,0.000006097549,0.000029314819,0.00033983553,0.000026157826,0.8088065,0.00025796617,0.00026931337,0.00015078203],"about_ca_topic_score_codex":0.000020061,"about_ca_topic_score_gemma":0.00028360717,"teacher_disagreement_score":0.18509167,"about_ca_system_score_codex":0.0000066839684,"about_ca_system_score_gemma":0.000012906188,"threshold_uncertainty_score":0.4339454},"labels":[],"label_agreement":null},{"id":"W1996475720","doi":"10.1017/s1461145705005572","title":"Gene expression of tryptophan hydroxylase 2 in post-mortem brain of suicide subjects","year":2005,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"TPH2; Tryptophan hydroxylase; Gene expression; Gene isoform; Biology; Dorsolateral prefrontal cortex; Gene; Internal medicine; Endocrinology; Serotonin; Prefrontal cortex; Genetics; Medicine; Neuroscience; Receptor","score_opus":0.023328999756662968,"score_gpt":0.32288418464526886,"score_spread":0.2995551848886059,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996475720","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894103,0.0001607797,0.00003418722,0.008507604,0.0012075393,0.00013325564,0.000018063261,0.000007560175,0.000520732],"genre_scores_gemma":[0.9935371,0.00022074826,0.0001465855,0.0056838975,0.0003025709,0.0000025050688,7.41705e-7,0.000018238434,0.00008758905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978169,0.00039976725,0.00082538807,0.00018974365,0.00056610873,0.00020204882],"domain_scores_gemma":[0.9978525,0.00088898727,0.0008187409,0.00015371923,0.00021234364,0.00007370832],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040114747,0.0001433252,0.0002729833,0.00042404668,0.00002666331,0.00001119269,0.0012504524,0.000053211552,0.00032534552],"category_scores_gemma":[0.00059743854,0.00010529336,0.00016426138,0.00024844613,0.00021106153,0.00021099493,0.00011123809,0.0003567494,0.000010163685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017901353,0.00045741387,0.00020987968,0.0000055058363,0.000018876093,0.0001831384,0.00037947047,0.0012414895,0.9901082,0.00009752766,0.0011410547,0.004367308],"study_design_scores_gemma":[0.0033455389,0.00030721864,0.008868703,0.00003485282,0.00000852341,0.00044343015,0.000052194948,0.00020077584,0.9855781,0.00028713778,0.00079363445,0.000079880905],"about_ca_topic_score_codex":0.000010013128,"about_ca_topic_score_gemma":0.000010323419,"teacher_disagreement_score":0.008658823,"about_ca_system_score_codex":0.000042058524,"about_ca_system_score_gemma":0.00010979583,"threshold_uncertainty_score":0.42937383},"labels":[],"label_agreement":null},{"id":"W1997436465","doi":"10.1016/j.pnpbp.2010.04.022","title":"Minocycline and psychoneuroimmunology in schizophrenia","year":2010,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Psychoneuroimmunology; Minocycline; Schizophrenia (object-oriented programming); Psychology; Medicine; Psychiatry; Immunology; Biology; Immune system; Antibiotics","score_opus":0.021797123722234097,"score_gpt":0.31550725772739185,"score_spread":0.2937101340051578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997436465","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855128,0.0022802497,0.0000015407799,0.0073009925,0.0037433023,0.0005192711,0.000010133075,0.0001131754,0.0005185443],"genre_scores_gemma":[0.9900159,0.0017301972,0.00061665045,0.007311677,0.0001780184,0.00010955179,0.000002371159,0.000020182697,0.000015454745],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9972014,0.00038477752,0.0005038614,0.0011718703,0.00009891966,0.0006391621],"domain_scores_gemma":[0.9989645,0.0004998319,0.00012700782,0.0002439813,0.000011447461,0.00015321453],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025760254,0.0003456169,0.00039641056,0.0003437525,0.00013194067,0.00003761273,0.00041976682,0.00046132138,0.00015579654],"category_scores_gemma":[0.0002307678,0.0002773463,0.000055253193,0.0005322948,0.0015886897,0.00012083845,0.00018100729,0.0016194591,0.000020957876],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023452658,0.0008665462,0.90562695,0.000022180615,0.0000045271104,0.00009399635,0.00004596255,2.9111612e-7,0.05610878,0.00458483,0.0002408889,0.030059773],"study_design_scores_gemma":[0.0070941197,0.00041043063,0.9786881,0.000011566731,0.00000405088,0.0002121453,0.000020202811,0.00007143037,0.00036685733,0.00986702,0.0029338275,0.000320203],"about_ca_topic_score_codex":0.000002894879,"about_ca_topic_score_gemma":0.00007765165,"teacher_disagreement_score":0.07306119,"about_ca_system_score_codex":0.0000035529135,"about_ca_system_score_gemma":0.000027415868,"threshold_uncertainty_score":0.9999679},"labels":[],"label_agreement":null},{"id":"W1997972581","doi":"10.1038/tp.2011.12","title":"Gene expression biomarkers of response to citalopram treatment in major depressive disorder","year":2011,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Antidepressant; Citalopram; Major depressive disorder; Oncology; Medicine; IRF7; Internal medicine; Bipolar disorder; Psychiatry; Psychology; Bioinformatics; Pharmacology; Biology; Hippocampus; Mood; Receptor","score_opus":0.029997562283437418,"score_gpt":0.2768814214067419,"score_spread":0.24688385912330446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997972581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949466,0.0002254394,0.00090905,0.0010561594,0.00024234057,0.0004554063,0.00008066014,0.000034679353,0.0020496908],"genre_scores_gemma":[0.9909621,0.000009142557,0.008615315,0.00022608801,0.000019709985,0.00005165364,0.0000063819625,0.00001883231,0.00009078586],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99875736,0.0001524002,0.00028839117,0.00036837842,0.00022753989,0.00020593095],"domain_scores_gemma":[0.99946797,0.00014783323,0.00006559008,0.00021684292,0.00001492916,0.00008682426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008964728,0.00015567687,0.00014579507,0.00024523042,0.00006033022,0.000006672726,0.00017795521,0.0000702109,0.00030447214],"category_scores_gemma":[0.0000460988,0.0001354311,0.000092395436,0.00038584246,0.000073341784,0.00012067228,0.000011725668,0.000053966534,0.00003363342],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0090630045,0.0015323127,0.12343388,0.000025058984,0.00002191299,0.000009269631,0.0039568944,0.00020809693,0.85584456,0.0013586293,0.00019800784,0.004348401],"study_design_scores_gemma":[0.0041881544,0.00033104306,0.5913869,0.0000507879,0.000009284531,0.000005473804,0.0002069083,0.000050992538,0.39691317,0.006264301,0.00033753875,0.00025540966],"about_ca_topic_score_codex":0.000057284433,"about_ca_topic_score_gemma":0.00014769951,"teacher_disagreement_score":0.46795306,"about_ca_system_score_codex":0.000015090237,"about_ca_system_score_gemma":0.000110651985,"threshold_uncertainty_score":0.55227196},"labels":[],"label_agreement":null},{"id":"W1998411100","doi":"10.1016/j.bbi.2003.11.005","title":"Considering cytokine panels","year":2003,"lang":"en","type":"letter","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Major depressive disorder; Pathogenesis; Cytokine; Immunology; Medicine; Inflammation; Immune system; Population; Proinflammatory cytokine; Tumor necrosis factor alpha; Immunotherapy; Bioinformatics; Biology; Psychiatry","score_opus":0.05936914177215945,"score_gpt":0.2818183369620792,"score_spread":0.22244919518991974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998411100","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7028865,0.00039853703,0.00003617811,0.28427076,0.0013096416,0.001226969,0.00038280315,0.00041311435,0.009075499],"genre_scores_gemma":[0.08527878,0.00016212436,0.00009079667,0.907104,0.00030449886,0.00009868426,0.000081819235,0.00010698702,0.0067722774],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977128,0.000510335,0.00032479118,0.0005784469,0.00030670717,0.0005669047],"domain_scores_gemma":[0.9984236,0.00064891845,0.00014446386,0.0006709647,0.000026852444,0.000085224085],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001784243,0.00043922133,0.00042972196,0.00017373703,0.0003913779,0.00016854618,0.00038674663,0.00059999246,0.000534373],"category_scores_gemma":[0.00064467615,0.00042972376,0.00014169558,0.00020861755,0.0004480131,0.00014849617,0.00017488391,0.0021712864,0.000068408495],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008392639,0.00010619254,0.00021932076,0.000089905596,0.0000065099084,0.00070594903,0.00023835505,1.107673e-7,0.17654863,0.000061683655,0.8161671,0.0058478676],"study_design_scores_gemma":[0.0006961781,0.00008277036,0.0044719917,0.000045513545,0.000038431168,0.00039758772,0.00010084735,0.0000010144622,0.052950837,0.0002456598,0.9403004,0.0006687599],"about_ca_topic_score_codex":0.000101623904,"about_ca_topic_score_gemma":0.000004089953,"teacher_disagreement_score":0.62283325,"about_ca_system_score_codex":0.00003386717,"about_ca_system_score_gemma":0.00006782915,"threshold_uncertainty_score":0.99981546},"labels":[],"label_agreement":null},{"id":"W1999147591","doi":"10.1371/annotation/11698dd2-0bc1-4fe0-ad92-b161b5594e81","title":"Correction: Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal; McGill University Health Centre","funders":"GIS-Institut des Maladies Rares; McGill University; Canadian Institutes of Health Research; Canadian Foundation for AIDS Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Human immunodeficiency virus (HIV); Table (database); Catabolism; Correct name; Balance (ability); Biology; Immunology; Computer science; Data mining; Biochemistry; Enzyme; Neuroscience","score_opus":0.020300915836847927,"score_gpt":0.2201954749990122,"score_spread":0.19989455916216428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999147591","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99300843,0.00052449043,0.000027285942,0.0010953463,0.00013840906,0.00035049286,0.000013350602,0.00009310237,0.004749106],"genre_scores_gemma":[0.99780434,0.00034025317,0.00012359349,0.00050822046,0.000093822484,0.000047684636,0.000003214415,0.000017558505,0.0010612998],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987632,0.00011905959,0.00017709474,0.0004355704,0.00021840342,0.00028665035],"domain_scores_gemma":[0.9993249,0.00029126697,0.000073409756,0.00018294709,0.000017243417,0.000110193876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011854059,0.00015589806,0.00027323133,0.00008438144,0.00011274113,0.00007266834,0.000115303475,0.000060172802,0.00001985338],"category_scores_gemma":[0.0007512199,0.00014332244,0.000019803425,0.0002119611,0.00022760412,0.00014763194,0.000053608695,0.0001679748,0.000017968661],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014913279,0.0055013597,0.4194414,0.0007325193,0.00010244144,0.000081690334,0.0059934002,0.000020038658,0.4267439,0.011079319,0.0038129548,0.12499965],"study_design_scores_gemma":[0.014074584,0.00041268003,0.79179054,0.0010590706,0.00007174841,0.00003475814,0.0003789127,0.044820726,0.13558127,0.003251421,0.007261242,0.0012630253],"about_ca_topic_score_codex":0.00001814778,"about_ca_topic_score_gemma":0.000060649632,"teacher_disagreement_score":0.37234914,"about_ca_system_score_codex":0.000013934547,"about_ca_system_score_gemma":0.0000135769,"threshold_uncertainty_score":0.584452},"labels":[],"label_agreement":null},{"id":"W1999584548","doi":"10.1016/j.jad.2011.12.037","title":"Does depression lead to influenza? — A systematic literature analysis","year":2012,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"University of Tennessee","keywords":"PsycINFO; Depression (economics); MEDLINE; Medicine; Inclusion and exclusion criteria; Psychiatry; Influenza A virus; Major depressive disorder; Clinical psychology; Immunology; Alternative medicine; Virus; Pathology; Biology; Cognition","score_opus":0.02708983191829381,"score_gpt":0.3337482048570695,"score_spread":0.30665837293877574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999584548","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002761362,0.9963135,0.00062091305,0.000030692674,0.00085596216,0.001502081,0.00004329936,0.000032952146,0.0003244455],"genre_scores_gemma":[0.0045430837,0.9945007,0.00008033128,0.00033793354,0.00021685575,0.00008745123,0.0000040941886,0.00007825251,0.00015127151],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99541444,0.0015246487,0.0012129004,0.00052888587,0.0007860639,0.0005330634],"domain_scores_gemma":[0.9954655,0.0016013482,0.0019028367,0.00053839514,0.00016197524,0.0003299083],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00070577144,0.0006902416,0.0032624595,0.0022048263,0.00015760727,0.00023504758,0.0009036982,0.00038765484,0.000046947313],"category_scores_gemma":[0.0026141603,0.00033624977,0.0023476365,0.0044726296,0.00008525698,0.00052822876,0.00014568532,0.00097646046,0.00007354514],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008621243,0.00062640524,0.00023516058,0.2467429,0.0025234974,0.00006563273,0.0025675197,0.00007840079,0.00011083133,0.00009188855,0.0004321821,0.7464394],"study_design_scores_gemma":[0.0016243373,0.0007038611,0.0003882656,0.3168264,0.02588108,0.00027334839,0.0008910411,0.000020323565,0.00026443735,0.00044639246,0.6502459,0.002434598],"about_ca_topic_score_codex":0.0000057581233,"about_ca_topic_score_gemma":0.00005835541,"teacher_disagreement_score":0.7440048,"about_ca_system_score_codex":0.00018837204,"about_ca_system_score_gemma":0.0001400509,"threshold_uncertainty_score":0.9999089},"labels":[],"label_agreement":null},{"id":"W1999891152","doi":"10.1177/0269881110364268","title":"Schizophrenia genes, epigenetics and psychoneuroimmunology therapeutics: all make sense now?","year":2010,"lang":"en","type":"article","venue":"Journal of Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Psychoneuroimmunology; Schizophrenia (object-oriented programming); Epigenetics; Psychology; Schizophrenia research; Epigenesis; Immune system; Neuroscience; Psychotherapist; Bioinformatics; Medicine; Psychiatry; Gene; Immunology; Biology; Genetics; DNA methylation; Gene expression","score_opus":0.02836196543901895,"score_gpt":0.3244793343122893,"score_spread":0.29611736887327034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999891152","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987457,0.0017259873,0.00008882002,0.00445732,0.005448797,0.00015645403,0.000007373684,0.000029302517,0.0006289628],"genre_scores_gemma":[0.9768406,0.008788741,0.0015765289,0.011920138,0.00058235874,0.0000037360735,3.5711932e-7,0.000041052885,0.00024649213],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981857,0.00028055208,0.0005652024,0.0003354287,0.0002162042,0.0004169027],"domain_scores_gemma":[0.9986585,0.00036463272,0.00044956483,0.00024565915,0.00009550971,0.00018616447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002814432,0.00023459892,0.00033683813,0.00029487725,0.000109304216,0.000043671866,0.00040398192,0.00022135317,0.00034599553],"category_scores_gemma":[0.000071317125,0.00020288909,0.00012726538,0.0002101642,0.00046961897,0.000091840586,0.00006260537,0.0010770637,0.00006690932],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001082308,0.00023427671,0.0002707228,0.000007568328,0.000054112737,0.00018850074,0.00017623657,0.0000049595806,0.96888167,0.00024108606,0.0030298315,0.025828714],"study_design_scores_gemma":[0.012013484,0.0011811078,0.019844908,0.000009637698,0.00013209994,0.0068165567,0.00007425509,0.0001329009,0.31042024,0.0050840755,0.6438085,0.00048223615],"about_ca_topic_score_codex":0.0000014064553,"about_ca_topic_score_gemma":0.000018621256,"teacher_disagreement_score":0.65846145,"about_ca_system_score_codex":0.000010452605,"about_ca_system_score_gemma":0.00007960987,"threshold_uncertainty_score":0.8273577},"labels":[],"label_agreement":null},{"id":"W2000183088","doi":"10.1038/npp.2010.39","title":"Reduction of Endogenous Kynurenic Acid Formation Enhances Extracellular Glutamate, Hippocampal Plasticity, and Cognitive Behavior","year":2010,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":232,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Kynurenic acid; Neuroscience; NMDA receptor; Kynurenine; Glutamate receptor; Hippocampal formation; Synaptic plasticity; Glutamatergic; Long-term potentiation; Hippocampus; Chemistry; Microdialysis; Quinolinic acid; Pharmacology; Psychology; Receptor; Biology; Central nervous system; Biochemistry; Amino acid","score_opus":0.02805764927671617,"score_gpt":0.2902347595278434,"score_spread":0.2621771102511272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000183088","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99622387,0.0001083811,0.0001498694,0.00008232005,0.0019713163,0.0005318695,0.0000343456,0.00008775104,0.00081026496],"genre_scores_gemma":[0.99929184,0.00015392364,0.000067652734,0.00019920399,0.00013667067,0.000078612175,0.0000041544035,0.000023474746,0.000044495067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854684,0.00018747406,0.00033453756,0.0004292584,0.00018817313,0.00031373664],"domain_scores_gemma":[0.9992821,0.00021746382,0.00022958191,0.00010036544,0.000060160703,0.00011028469],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008559768,0.00018982208,0.00021074028,0.000168368,0.00015519968,0.000025579462,0.0001871696,0.00012291747,0.00038056253],"category_scores_gemma":[0.00019301873,0.00018902613,0.00005596707,0.00024816045,0.00047125152,0.0002843306,0.000053353557,0.0004241859,0.000045448964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031789517,0.00028583762,0.000061182436,0.00002997768,0.000004718958,0.000036700007,0.0003678427,0.0000014142529,0.98493946,0.0001338947,0.0000614176,0.013759648],"study_design_scores_gemma":[0.0016876971,0.00035270935,0.0030087736,0.000006109788,0.00005871649,0.00069718284,0.000087184,0.00009400365,0.99346256,0.0001550809,0.00023232325,0.00015766559],"about_ca_topic_score_codex":0.0000034625034,"about_ca_topic_score_gemma":0.0000055536643,"teacher_disagreement_score":0.013601982,"about_ca_system_score_codex":0.0000062460313,"about_ca_system_score_gemma":0.00003043072,"threshold_uncertainty_score":0.7708262},"labels":[],"label_agreement":null},{"id":"W2000467119","doi":"10.1016/j.jalz.2011.05.1056","title":"P2‐169: NSAID use does not affect dementia progression or survival in Alzheimer's disease. The Cache County Dementia Progression Study.","year":2011,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Dementia; Medicine; Clinical Dementia Rating; Alzheimer's disease; Population; Proportional hazards model; Rating scale; Disease; Internal medicine; Psychology","score_opus":0.08544353536424518,"score_gpt":0.32124875449668455,"score_spread":0.23580521913243938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000467119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9541637,0.033649728,0.00009098725,0.000648892,0.0027468696,0.0071422122,0.00014491002,0.0005549783,0.00085778214],"genre_scores_gemma":[0.9974557,0.0002318687,0.00050030084,0.00074138516,0.00013201463,0.00075971877,0.000032565353,0.0001282498,0.00001817923],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.992971,0.0014878033,0.0009925734,0.0016422258,0.0015523094,0.0013541062],"domain_scores_gemma":[0.99713856,0.00044867294,0.00053476874,0.0013649496,0.00010396037,0.00040908295],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001248999,0.0008291506,0.0005566308,0.000265949,0.0008767441,0.00043277923,0.0015141165,0.00017629543,0.001134163],"category_scores_gemma":[0.00028336118,0.00048062808,0.00026544704,0.0008883974,0.0005389764,0.001183265,0.0008592993,0.00054315256,0.00016100073],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045634513,0.010227623,0.8294416,0.000048035898,0.014560952,0.0008230467,0.0043800357,0.00002068503,0.021631213,0.0011317345,0.003983151,0.109188445],"study_design_scores_gemma":[0.0054626013,0.0010992928,0.762033,0.00021414722,0.023055525,0.000008710626,0.0012198921,0.00043671936,0.19563009,0.00032306972,0.008765273,0.001751682],"about_ca_topic_score_codex":0.0004139259,"about_ca_topic_score_gemma":0.0015053108,"teacher_disagreement_score":0.17399888,"about_ca_system_score_codex":0.000015663829,"about_ca_system_score_gemma":0.00021064321,"threshold_uncertainty_score":0.9997789},"labels":[],"label_agreement":null},{"id":"W2000663401","doi":"10.1016/j.molimm.2011.08.017","title":"IDO expression by human B lymphocytes in response to T lymphocyte stimuli and TLR engagement is biologically inactive","year":2011,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; PROTEO; Université de Montréal; Hôpital Notre-Dame","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Lymphocyte; Immunology; Cell biology; Chemistry; Biology","score_opus":0.03837866340450858,"score_gpt":0.27965258985653285,"score_spread":0.24127392645202428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000663401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99689585,0.0007460072,0.00032877244,0.00026985188,0.000071308554,0.0003537019,0.000012014889,0.00006751348,0.0012549903],"genre_scores_gemma":[0.99577224,0.00010113986,0.0004174415,0.0034332639,0.0000031368243,0.000071479786,0.0000025985837,0.000020544207,0.0001781516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99767405,0.000913412,0.00024156245,0.00064006884,0.00011613725,0.0004147533],"domain_scores_gemma":[0.99930245,0.00017883179,0.00007239737,0.00035365124,0.000019562887,0.00007311905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002593319,0.00021728502,0.00023228423,0.00022125717,0.00014796737,0.000022736253,0.00036653227,0.00016618351,0.00024007847],"category_scores_gemma":[0.00056914904,0.00019495937,0.00004396634,0.00026435775,0.00027612087,0.00007607891,0.0004046438,0.00016098392,0.00009062653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014683121,0.00016754851,0.0001439085,0.0000030842657,0.0000073342085,0.000116930496,0.0018991781,0.0000014376574,0.99305165,0.00034687432,0.00019550894,0.0025982093],"study_design_scores_gemma":[0.0018014279,0.0007549683,0.009701408,0.000020891568,0.000002652343,0.000014042233,0.0002683308,0.0000092649325,0.9826556,0.00063341414,0.0039047762,0.00023325093],"about_ca_topic_score_codex":0.000094453084,"about_ca_topic_score_gemma":0.0000027781898,"teacher_disagreement_score":0.0103961015,"about_ca_system_score_codex":0.0001358016,"about_ca_system_score_gemma":0.00004470606,"threshold_uncertainty_score":0.79502124},"labels":[],"label_agreement":null},{"id":"W2000838828","doi":"10.1016/j.socscimed.2010.03.012","title":"Life course socioeconomic position is associated with inflammatory markers: The Framingham Offspring Study","year":2010,"lang":"en","type":"article","venue":"Social Science & Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":140,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; Canadian Institutes of Health Research","keywords":"Life course approach; Body mass index; Internal medicine; Framingham Risk Score; Fibrinogen; C-reactive protein; Medicine; Offspring; Lipoprotein-associated phospholipase A2; Immunology; Endocrinology; Demography; Inflammation; Gerontology; Disease; Cholesterol; Lipoprotein; Biology; Psychology; Pregnancy; Genetics","score_opus":0.012969136350810094,"score_gpt":0.2767407921470704,"score_spread":0.26377165579626033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000838828","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98635954,0.000011425859,0.000008757404,0.008099929,0.000637744,0.00049107376,0.0000032423377,0.00010227282,0.004285989],"genre_scores_gemma":[0.9932441,0.0000025388176,0.000001986059,0.006212807,0.0003693884,0.000022563014,6.595467e-7,0.000015048272,0.0001309114],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99787056,0.000117832904,0.00024205266,0.00048458198,0.00080904714,0.00047593872],"domain_scores_gemma":[0.9989638,0.000271417,0.00022117383,0.0002510205,0.00008349414,0.00020914483],"candidate_categories":["sts"],"consensus_categories":["sts"],"category_scores_codex":[0.0015961485,0.00017032775,0.00020823347,0.0000876475,0.0015125333,0.00010118433,0.0007351717,0.000076167555,0.00034573334],"category_scores_gemma":[0.0016724442,0.00010853661,0.000040894436,0.00058821624,0.0036742068,0.00037374935,0.00007725707,0.0005097383,0.0000359113],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017423785,0.0009746915,0.23700607,0.000015904747,0.0000737635,0.00006244672,0.14061336,0.000005355804,0.5937781,0.006287159,0.009944787,0.011064133],"study_design_scores_gemma":[0.0028515856,0.0005240174,0.9603138,0.00004407778,0.00007572918,0.000008452025,0.02892537,0.0003377633,0.0046712356,0.00096254004,0.0008574656,0.00042795518],"about_ca_topic_score_codex":0.00005346607,"about_ca_topic_score_gemma":0.00013666364,"teacher_disagreement_score":0.7233077,"about_ca_system_score_codex":0.00008078812,"about_ca_system_score_gemma":0.0005168899,"threshold_uncertainty_score":0.9997874},"labels":[],"label_agreement":null},{"id":"W2001678293","doi":"10.1111/j.1398-9995.2008.01809.x","title":"Tryptophan catabolites regulate mucosal sensitization to ovalbumin in respiratory airways","year":2008,"lang":"en","type":"article","venue":"Allergy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Sensitization; Ovalbumin; Nasal administration; Medicine; Immunology; Allergic inflammation; Methacholine; Immune tolerance; Inflammation; Pharmacology; Immune system; Internal medicine; Lung; Respiratory disease","score_opus":0.03592055255355045,"score_gpt":0.2547131303196969,"score_spread":0.21879257776614644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001678293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99261004,0.00012028567,0.000064913875,0.0008985143,0.00019340051,0.00019453376,0.000007902535,0.00010478741,0.005805609],"genre_scores_gemma":[0.99408007,0.00009030001,0.00014260238,0.00436339,0.00013261834,0.000018070677,0.000006320185,0.000030091893,0.0011365123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853945,0.00013236555,0.00024313743,0.00046763656,0.00024525955,0.0003721754],"domain_scores_gemma":[0.9993312,0.00014941346,0.000047983725,0.00031500534,0.000024800105,0.0001316173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007899203,0.000160848,0.00016530792,0.00024495585,0.00013048555,0.000018850818,0.00020589313,0.000080361475,0.00008710375],"category_scores_gemma":[0.00049813883,0.00016802717,0.000047143272,0.0006811775,0.0000978557,0.00016793785,0.00007568757,0.00010234626,0.00023998246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010713451,0.00018438807,0.0014357289,0.00001886664,0.0000038070325,0.00024654658,0.0018958792,0.001026034,0.97173995,0.008352134,0.00982717,0.0051623746],"study_design_scores_gemma":[0.0013906027,0.0001294325,0.14117523,0.00003961051,0.0000010997721,0.000037058267,0.00006590926,0.00027992492,0.79890496,0.0010285367,0.056473896,0.00047375596],"about_ca_topic_score_codex":0.00006277106,"about_ca_topic_score_gemma":0.00020629227,"teacher_disagreement_score":0.17283499,"about_ca_system_score_codex":0.000036967842,"about_ca_system_score_gemma":0.00007333277,"threshold_uncertainty_score":0.6851949},"labels":[],"label_agreement":null},{"id":"W2001795663","doi":"10.1097/00007890-201007272-00083","title":"INDUCTION OF KIDNEY ALLOGRAFT TOLERANCE BY MESENCHYMAL STEM CELLS ASSOCIATED WITH INDOLEAMINE 2,3-DIOXYGENASE EXPRESSION","year":2010,"lang":"en","type":"article","venue":"Transplantation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Mesenchymal stem cell; Kidney; Biology; Cell biology; Cancer research; Medicine; Genetics; Tryptophan","score_opus":0.01214924712923721,"score_gpt":0.22083352396447573,"score_spread":0.20868427683523852,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001795663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977033,0.0000074000536,0.0010233723,0.00008296163,0.00020828402,0.00024263884,0.00022777921,0.000083486506,0.00042079057],"genre_scores_gemma":[0.99928004,0.000042165248,0.00013881785,0.00021828424,0.000022618207,0.00001550708,0.00007142837,0.000017605915,0.00019354149],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890655,0.000093427574,0.00021108716,0.0002922255,0.0003077316,0.00018895228],"domain_scores_gemma":[0.99944437,0.00010181358,0.00015509602,0.00013986308,0.000038071936,0.00012079053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009891016,0.00014080564,0.00014483005,0.000077022785,0.00008218046,0.000018396999,0.00013565371,0.00011900282,0.000056223416],"category_scores_gemma":[0.000039722578,0.000117412455,0.000035737634,0.00027822744,0.000106796215,0.0002716116,0.000004113768,0.00022096993,0.000007071053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002106693,0.00015154583,0.0002992432,0.00004648919,0.0000035599114,0.0000063089,0.0006468485,0.000047980222,0.99762255,0.00004407845,0.000374178,0.00054653257],"study_design_scores_gemma":[0.0016371587,0.00011619493,0.003081038,0.00008176716,0.0000070716396,0.000008594253,0.00005484573,0.0001353171,0.994483,0.000018531935,0.0002308419,0.00014562084],"about_ca_topic_score_codex":0.000013041499,"about_ca_topic_score_gemma":0.000042308555,"teacher_disagreement_score":0.003139548,"about_ca_system_score_codex":0.00000858363,"about_ca_system_score_gemma":0.000046691322,"threshold_uncertainty_score":0.4787941},"labels":[],"label_agreement":null},{"id":"W2002506050","doi":"10.1007/s00432-012-1259-2","title":"Induction of indoleamine-2,3 dioxygenase in bone marrow stromal cells inhibits myeloma cell growth","year":2012,"lang":"en","type":"article","venue":"Journal of Cancer Research and Clinical Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Stem Cell Network","keywords":"Stromal cell; Indoleamine 2,3-dioxygenase; Hematology; Bone marrow; Multiple myeloma; Cancer research; Internal medicine; Biology; Medicine; Immunology; Tryptophan; Biochemistry","score_opus":0.1370004635262769,"score_gpt":0.45503393670386916,"score_spread":0.31803347317759223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002506050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956014,0.0010283563,0.000005088196,0.00149577,0.0005131013,0.00015176274,0.000007128396,0.000003079369,0.0011942964],"genre_scores_gemma":[0.9941261,0.004764843,0.00010365042,0.0002319608,0.0005677498,0.0000054528236,2.1459398e-7,0.000011434078,0.0001886263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967282,0.001000623,0.0009875967,0.00019711543,0.000568504,0.0005179812],"domain_scores_gemma":[0.9970265,0.0017667792,0.00048009361,0.00010690617,0.00022464809,0.00039507673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030453554,0.000101944424,0.0004873583,0.00035353607,0.00005374214,0.0000142097,0.00022443764,0.00023192368,0.000101181206],"category_scores_gemma":[0.0015152148,0.000079688376,0.00011075728,0.0004906044,0.0006508808,0.00031672325,0.00012450908,0.0013065161,0.0000069586786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002819533,0.0028609629,0.029981412,0.000088073815,0.00001708525,0.00013378683,0.0003170339,0.0000038348035,0.9159193,0.00032993584,0.0027953885,0.04473367],"study_design_scores_gemma":[0.0047439123,0.0055007734,0.117574535,0.00007136471,0.0000061667897,0.00005947986,0.00050556555,0.000007286807,0.8663135,0.0007588122,0.0043436154,0.00011497333],"about_ca_topic_score_codex":0.0000810965,"about_ca_topic_score_gemma":0.00008006075,"teacher_disagreement_score":0.08759312,"about_ca_system_score_codex":0.00012125721,"about_ca_system_score_gemma":0.0005159734,"threshold_uncertainty_score":0.5676235},"labels":[],"label_agreement":null},{"id":"W2003516592","doi":"10.1017/neu.2014.13","title":"Can BDNF and IL-2 be indicators for the diagnosis in schizophrenic patients with depressive symptoms?","year":2014,"lang":"en","type":"article","venue":"Acta Neuropsychiatrica","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Depressive symptoms; Schizophrenia (object-oriented programming); Psychology; Clinical psychology; Psychiatry; Medicine; Internal medicine; Anxiety","score_opus":0.008422431718388673,"score_gpt":0.21932086012322538,"score_spread":0.21089842840483672,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003516592","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993578,0.00005806546,0.00002534015,0.0049687554,0.00024209777,0.00076530327,0.000053089807,0.000052448744,0.00025689582],"genre_scores_gemma":[0.99579173,0.00013075166,0.000054217573,0.003709878,0.00005921867,0.0001920021,0.0000030997817,0.000040414794,0.000018686733],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984726,0.00014425728,0.00019807555,0.0005588022,0.00025575352,0.00037055017],"domain_scores_gemma":[0.9980142,0.0013147499,0.00015602936,0.00038794373,0.000017445138,0.00010960843],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006735139,0.00020822424,0.0001724537,0.00021758211,0.00026689796,0.0000788361,0.00044487047,0.00005460209,0.000010851113],"category_scores_gemma":[0.0006646894,0.00013364453,0.000050763054,0.0007134082,0.00017251879,0.00011557589,0.00009174899,0.00021473599,0.000002328156],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004902941,0.00057283323,0.9402208,0.000041810617,0.000020830837,0.0000031811,0.00046789655,0.000024085613,0.00046861096,0.002617348,0.0049772076,0.050095137],"study_design_scores_gemma":[0.0036974829,0.00057890656,0.9780022,0.000013239208,0.000033307624,0.0000026994094,0.000021941189,0.0002221488,0.000814144,0.00043007184,0.015892886,0.00029096208],"about_ca_topic_score_codex":0.000024151534,"about_ca_topic_score_gemma":0.00007770707,"teacher_disagreement_score":0.049804173,"about_ca_system_score_codex":0.000011613029,"about_ca_system_score_gemma":0.000036518555,"threshold_uncertainty_score":0.54498655},"labels":[],"label_agreement":null},{"id":"W2003944625","doi":"10.1111/j.1600-0765.2012.01515.x","title":"Diazepam reverses the alveolar bone loss and hippocampal interleukin‐1beta and interleukin‐6 enhanced by conditioned fear stress in ligature‐induced periodontal disease in rats","year":2012,"lang":"en","type":"article","venue":"Journal of Periodontal Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Diazepam; Periodontitis; Dental alveolus; Medicine; Internal medicine; Interleukin; Hippocampal formation; Hippocampus; Endocrinology; Anesthesia; Cytokine; Dentistry","score_opus":0.038899268039325786,"score_gpt":0.3363091103314538,"score_spread":0.29740984229212797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003944625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99505496,0.0026339483,0.0000036869635,0.0014633042,0.00024069195,0.00040193516,0.00005173297,0.0000087262715,0.00014102654],"genre_scores_gemma":[0.9986708,0.00066974055,0.000018214603,0.00027542913,0.00015649894,0.000020734884,0.0000039588153,0.000029428875,0.0001551976],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.996408,0.00090995437,0.00058043393,0.00037362115,0.00093283335,0.00079515105],"domain_scores_gemma":[0.99825555,0.0006760239,0.00019490099,0.00024559372,0.000100077625,0.00052785676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015764128,0.00025566973,0.00042788874,0.00047428347,0.00027873833,0.00032316873,0.0004578944,0.00013069846,0.00008959702],"category_scores_gemma":[0.0017410332,0.0001867588,0.00011883666,0.0005438081,0.00082828844,0.0010608594,0.00032260802,0.0015071887,0.000009905302],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017137801,0.0006117545,0.060782697,0.00009621281,0.00001738752,0.0003601318,0.012083478,0.000001637673,0.91977775,0.00016436944,0.0006961177,0.003694664],"study_design_scores_gemma":[0.005287223,0.0011407887,0.5731963,0.0009052371,0.000020515276,0.0003505262,0.022324637,0.00008244733,0.3940689,0.0004405466,0.0015639643,0.0006189257],"about_ca_topic_score_codex":0.00021323224,"about_ca_topic_score_gemma":0.0006219633,"teacher_disagreement_score":0.52570885,"about_ca_system_score_codex":0.00022843115,"about_ca_system_score_gemma":0.00019172256,"threshold_uncertainty_score":0.7615803},"labels":[],"label_agreement":null},{"id":"W2004512673","doi":"10.1016/j.rmed.2011.10.023","title":"Association between asthma medications and suicidal ideation in adult asthmatics","year":2012,"lang":"en","type":"article","venue":"Respiratory Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Heart Institute; Hôpital du Sacré-Cœur de Montréal; Concordia University; Université de Montréal; Université du Québec à Montréal","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Asthma; Suicidal ideation; Cohabitation; Anxiety; Depression (economics); Internal medicine; Spirometry; Theophylline; Psychiatry; Poison control; Injury prevention; Emergency medicine","score_opus":0.038097976388300626,"score_gpt":0.3088546361189614,"score_spread":0.27075665973066076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004512673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917923,0.000322324,0.00035415497,0.0037620899,0.00019224465,0.00021323134,0.0000065789945,0.000059557227,0.0032974917],"genre_scores_gemma":[0.996467,0.000048115697,0.000053488893,0.0027582392,0.0005004745,0.000017101467,0.0000057349725,0.000012648597,0.00013721011],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99853987,0.00020193208,0.00033335184,0.00018234573,0.00044691243,0.00029557053],"domain_scores_gemma":[0.9988258,0.00065805815,0.00016543615,0.00014972799,0.000040767107,0.0001602368],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007820185,0.00010981715,0.00018384747,0.00019528989,0.00008152988,0.00000919806,0.00010041639,0.000105901265,0.000096066295],"category_scores_gemma":[0.0038354741,0.00009441007,0.000016036523,0.0004010914,0.00010854885,0.00024093015,0.000026955946,0.00018711557,0.00004443571],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013880504,0.00012037375,0.90509313,0.000076732584,0.000016528293,0.0000033347783,0.0031621084,0.0000036532379,0.056546476,0.00915496,0.005795662,0.020013172],"study_design_scores_gemma":[0.0015252209,0.00012401878,0.9687356,0.000074270494,0.000018486136,0.0000023241194,0.00041912653,0.0000981617,0.009989958,0.0004833907,0.018362334,0.00016713077],"about_ca_topic_score_codex":0.000031571482,"about_ca_topic_score_gemma":0.000048652037,"teacher_disagreement_score":0.06364246,"about_ca_system_score_codex":0.00010631196,"about_ca_system_score_gemma":0.0000310539,"threshold_uncertainty_score":0.45916978},"labels":[],"label_agreement":null},{"id":"W2005158714","doi":"10.1111/j.1600-0897.2005.00299.x","title":"Reduced Uterine Indoleamine 2,3‐Dioxygenase Versus Increased Th1/Th2 Cytokine Ratios as a Basis for Occult and Clinical Pregnancy Failure in Mice and Humans","year":2005,"lang":"en","type":"article","venue":"American Journal of Reproductive Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; McMaster University; University of Toronto","funders":"European Commission","keywords":"Decidua; Terminal deoxynucleotidyl transferase; Pregnancy; Medicine; TUNEL assay; Miscarriage; Cytokine; Immune tolerance; Endocrinology; Internal medicine; Immunology; Fetus; Andrology; Immune system; Biology; Placenta; Immunohistochemistry","score_opus":0.02480345855445545,"score_gpt":0.32419317247782414,"score_spread":0.2993897139233687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005158714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99379575,0.00081644504,0.000072681505,0.004620949,0.00020153973,0.00039629752,0.00002008798,0.000017121796,0.000059119542],"genre_scores_gemma":[0.995669,0.0011942124,0.002413997,0.00033969292,0.0002708136,0.000019560232,0.0000018227078,0.000024384231,0.00006653194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976322,0.00049868564,0.00072348746,0.00067715737,0.00013998737,0.00032847543],"domain_scores_gemma":[0.99786246,0.00082597387,0.00072299276,0.00032819857,0.0001614097,0.00009898112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048637544,0.00022613216,0.0006224369,0.0002816967,0.00009803417,0.000028317763,0.00025773494,0.000075990356,0.000021271147],"category_scores_gemma":[0.0057798014,0.00019861478,0.0001115897,0.0003838604,0.0012161718,0.00032633173,0.00010209369,0.00044798187,0.0000029894134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007453067,0.0004908482,0.0013164218,0.000016214672,0.00014041961,0.000068187626,0.0011863813,0.0000074226377,0.872801,0.00020201212,0.000114146875,0.1162039],"study_design_scores_gemma":[0.022328341,0.018244969,0.16597487,0.0002988337,0.00008951206,0.0018510949,0.006300449,0.000046110268,0.7713601,0.0004406218,0.012267272,0.00079784775],"about_ca_topic_score_codex":0.00006787695,"about_ca_topic_score_gemma":0.000078009005,"teacher_disagreement_score":0.16465846,"about_ca_system_score_codex":0.000062865955,"about_ca_system_score_gemma":0.00013358418,"threshold_uncertainty_score":0.8099276},"labels":[],"label_agreement":null},{"id":"W2005701050","doi":"10.1073/pnas.1207191109","title":"Indole peroxygenase activity of indoleamine 2,3-dioxygenase","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Cancer Research Institute","keywords":"Indole test; Chemistry; Indoleamine 2,3-dioxygenase; Oxygen; Heme; Superoxide dismutase; Superoxide; Photochemistry; Hemeprotein; Tryptophan; Cytochrome; Stereochemistry; Biochemistry; Enzyme; Organic chemistry","score_opus":0.06803230485986562,"score_gpt":0.3144020644778551,"score_spread":0.24636975961798951,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005701050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99230784,0.00007171253,7.6142356e-7,0.0006793576,0.000024727313,0.0001537846,0.0000300659,0.000010874165,0.0067208507],"genre_scores_gemma":[0.9992578,0.000017530521,0.00021688793,0.00029461007,0.000063540654,0.0000056687622,2.4636597e-8,0.0000043946034,0.0001395457],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99810684,0.000014957916,0.00025936644,0.00020981162,0.0011801264,0.00022887597],"domain_scores_gemma":[0.9991268,0.00021094063,0.0004848655,0.000010387493,0.000108140404,0.00005889367],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009607016,0.00010087728,0.00016478456,0.00018064797,0.00014519022,0.00001068284,0.00081473304,0.000070903516,0.00002731942],"category_scores_gemma":[0.0018315618,0.00006728703,0.00009401019,0.0010319366,0.0011877306,0.00079708645,0.00017931842,0.0001538702,0.0000027802535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022982242,0.00017155799,0.0016237833,0.000050971783,0.000002717793,1.8104873e-9,0.00023858978,0.00001041141,0.97690976,0.020132447,0.00029818522,0.00053860067],"study_design_scores_gemma":[0.00019730689,0.0000330007,0.08349531,0.000030783795,0.0000017156506,0.000004424556,0.000117803764,0.00011385295,0.91166615,0.0041648443,0.00010810185,0.00006669948],"about_ca_topic_score_codex":0.0000052784576,"about_ca_topic_score_gemma":3.6978726e-8,"teacher_disagreement_score":0.08187153,"about_ca_system_score_codex":0.000019376197,"about_ca_system_score_gemma":0.00003231891,"threshold_uncertainty_score":0.4376243},"labels":[],"label_agreement":null},{"id":"W2006446152","doi":"10.1007/s00213-014-3582-6","title":"Oxidative stress and the antipsychotic-induced vacuous chewing movement model of tardive dyskinesia: evidence for antioxidant-based prevention strategies","year":2014,"lang":"en","type":"review","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Tardive dyskinesia; Oxidative stress; Antipsychotic; Medicine; Dyskinesia; Schizophrenia (object-oriented programming); Haloperidol; Pharmacology; Animal studies; Neuroscience; Psychology; Psychiatry; Internal medicine; Dopamine; Parkinson's disease","score_opus":0.1442252704170513,"score_gpt":0.4230700529886315,"score_spread":0.2788447825715802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006446152","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012733123,0.94925314,0.027750883,0.00042581634,0.0014933764,0.0077540665,0.00023831309,0.00010380887,0.00024748212],"genre_scores_gemma":[0.07451303,0.92297363,0.0004879589,0.000603936,0.00015782645,0.0010847982,0.000011200101,0.00007128932,0.00009631942],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9960764,0.0012075021,0.00092721917,0.0009915681,0.00031062015,0.00048670458],"domain_scores_gemma":[0.9950809,0.0031582715,0.0011228231,0.00043766765,0.00011164324,0.000088686145],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00088527444,0.00057175866,0.0016694057,0.0002552658,0.00021320704,0.00007916356,0.0007676728,0.00028917854,0.000032605127],"category_scores_gemma":[0.00040351233,0.00039599746,0.00058077136,0.00036511704,0.000520062,0.00022322084,0.00009121395,0.00040899427,0.000006031359],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0055968175,0.0018561952,0.000007695116,0.07632519,0.000959019,0.000016727578,0.0012542506,0.0020843914,0.15082991,0.018949538,0.0017133902,0.7404069],"study_design_scores_gemma":[0.17649303,0.009966499,0.0002359104,0.12987556,0.025300192,0.00012582657,0.0028658512,0.23998995,0.1604602,0.11920839,0.12155521,0.013923391],"about_ca_topic_score_codex":0.000008417618,"about_ca_topic_score_gemma":0.000005600671,"teacher_disagreement_score":0.72648346,"about_ca_system_score_codex":0.000044802677,"about_ca_system_score_gemma":0.0004094831,"threshold_uncertainty_score":0.9998492},"labels":[],"label_agreement":null},{"id":"W2006770834","doi":"10.1046/j.1524-475x.2003.11505.x","title":"Proliferation of peripheral blood mononuclear cells is suppressed by the indoleamine 2,3‐dioxygenase expression of interferon‐γ–treated skin cells in a co‐culture system","year":2003,"lang":"en","type":"article","venue":"Wound Repair and Regeneration","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Sick Kids Foundation","keywords":"Indoleamine 2,3-dioxygenase; Peripheral blood mononuclear cell; Kynurenine; Interferon gamma; Immune system; Interferon; Immunology; Cytokine; Monocyte; Human skin; Cell culture; Biology; Tryptophan; In vitro; Biochemistry","score_opus":0.008788480305289649,"score_gpt":0.2147096819185366,"score_spread":0.20592120161324695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006770834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99794614,0.0006013602,0.00011378167,0.000033090993,0.00009438332,0.0005596534,0.000046077592,0.000049397404,0.0005561111],"genre_scores_gemma":[0.9984804,0.00010131323,0.000096682495,0.000069937436,0.00002808941,0.000027349604,0.000013631427,0.000017177375,0.0011654334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986291,0.0003158847,0.0003657932,0.00034193572,0.00020150692,0.0001457702],"domain_scores_gemma":[0.9995305,0.000034031298,0.00013687433,0.00022069621,0.00003871472,0.000039166694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017099442,0.00016144117,0.00019658134,0.00006956118,0.00010166773,0.000049700182,0.00008756647,0.00014152653,0.000019144565],"category_scores_gemma":[0.00002278346,0.000101760685,0.00007274188,0.00019393567,0.00011472086,0.00013519902,0.000017997929,0.00012598587,0.0000020493062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000887159,0.00017619896,0.00004510227,0.00018980113,0.000007272851,0.0000025754114,0.0025076,0.00026198567,0.99286705,0.00025380275,0.0035512135,0.00004867395],"study_design_scores_gemma":[0.0008360085,0.00023194929,0.000029798559,0.00010844146,0.00000995212,0.000010709797,0.00075070944,0.003651925,0.99362105,0.000016800735,0.00062084786,0.0001118101],"about_ca_topic_score_codex":0.000027805956,"about_ca_topic_score_gemma":0.000015316296,"teacher_disagreement_score":0.0033899392,"about_ca_system_score_codex":0.000023364499,"about_ca_system_score_gemma":0.000025627163,"threshold_uncertainty_score":0.414968},"labels":[],"label_agreement":null},{"id":"W2007506824","doi":"10.1038/tp.2014.125","title":"Hippocampal and behavioral dysfunctions in a mouse model of environmental stress: normalization by agomelatine","year":2014,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Hippocampal formation; Agomelatine; Psychology; Neuroscience; Neuroplasticity; Endocrinology; Internal medicine; Hippocampus; Medicine; Antidepressant","score_opus":0.01657056993674825,"score_gpt":0.24309002480328615,"score_spread":0.2265194548665379,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007506824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989976,0.00008723678,0.008613309,0.0003066863,0.00006330539,0.00011910616,0.0004138403,0.000019418349,0.00040108306],"genre_scores_gemma":[0.9987333,0.000024808745,0.000891112,0.0001468315,0.00001668863,0.0000069163953,0.000058064976,0.000011165441,0.000111151174],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9992618,0.000040131094,0.00020277158,0.0001987654,0.00018608982,0.00011046762],"domain_scores_gemma":[0.99979234,0.000032320535,0.000050401715,0.000081888335,0.0000028642671,0.00004021686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047042373,0.000090612084,0.00008690556,0.0000827604,0.000052860007,0.00000816948,0.00006177586,0.000054831566,0.00009204213],"category_scores_gemma":[0.000005406659,0.00009559984,0.000030094965,0.00008527862,0.00009416593,0.00016420879,0.0000064519872,0.00008365958,0.0000036985864],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014713778,0.0013447548,0.2304317,0.00004768527,0.0000045088145,9.6036075e-8,0.0007948627,0.016891466,0.7286868,0.017735036,0.00020194345,0.0037140117],"study_design_scores_gemma":[0.012634064,0.0006387118,0.27165517,0.00008527611,0.000054553762,0.000008589103,0.0006426602,0.5666235,0.097131915,0.049008258,0.00030670388,0.0012105893],"about_ca_topic_score_codex":0.000007988568,"about_ca_topic_score_gemma":0.00006732794,"teacher_disagreement_score":0.63155484,"about_ca_system_score_codex":0.000005755922,"about_ca_system_score_gemma":0.00001815065,"threshold_uncertainty_score":0.38984483},"labels":[],"label_agreement":null},{"id":"W2008310054","doi":"10.1097/01.mco.0000134373.16557.92","title":"Interleukin-1?? system in anorectic catabolic tumor-bearing rats","year":2004,"lang":"en","type":"article","venue":"Current Opinion in Clinical Nutrition & Metabolic Care","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Cancer Institute","keywords":"Anorectic; Anorexia; Cytokine; Tumor necrosis factor alpha; Receptor; Endocrinology; Downregulation and upregulation; Internal medicine; Receptor antagonist; Cachexia; Biology; Medicine; Cancer; Antagonist; Biochemistry","score_opus":0.0967482416240348,"score_gpt":0.3921265531167847,"score_spread":0.2953783114927499,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008310054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96943426,0.015789254,0.00007452064,0.0003613039,0.012714842,0.0011006981,0.00007706464,0.00022261776,0.00022546558],"genre_scores_gemma":[0.99424994,0.004336018,0.000074664145,0.00021084899,0.0008100683,0.00023734703,0.00004998679,0.000028915409,0.0000022338638],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99604875,0.0006210422,0.001380677,0.0009622944,0.00043040136,0.0005568238],"domain_scores_gemma":[0.9984974,0.00049840147,0.00024539523,0.00046503966,0.00008284021,0.00021091483],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057026016,0.00031270555,0.0006779041,0.00053389795,0.00009789072,0.00009726055,0.00047776368,0.00015568109,0.000021148137],"category_scores_gemma":[0.001428054,0.00032010698,0.00029690147,0.0012607562,0.00020550929,0.0003104372,0.00015312902,0.0009082527,0.00017034239],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0046567414,0.030812731,0.19555882,0.028515724,0.000084627565,0.00038032903,0.022270884,0.0025869987,0.03386568,0.21337871,0.007945987,0.45994276],"study_design_scores_gemma":[0.060861643,0.0007613108,0.4893038,0.020051135,0.00005996339,0.00024985883,0.018808117,0.0004850776,0.05458907,0.0066734124,0.34460622,0.0035503886],"about_ca_topic_score_codex":0.000110273984,"about_ca_topic_score_gemma":0.00010767315,"teacher_disagreement_score":0.45639238,"about_ca_system_score_codex":0.0002209921,"about_ca_system_score_gemma":0.00016994064,"threshold_uncertainty_score":0.9999251},"labels":[],"label_agreement":null},{"id":"W2009170866","doi":"10.1186/1471-2202-14-105","title":"Meta-analysis of gene coexpression networks in the post-mortem prefrontal cortex of patients with schizophrenia and unaffected controls","year":2013,"lang":"en","type":"review","venue":"BMC Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Michael Smith Health Research BC; University of British Columbia; Canada's Michael Smith Genome Sciences Centre; University of British Columbia Hospital","funders":"National Institute of General Medical Sciences","keywords":"Schizophrenia (object-oriented programming); Biology; Neuroscience; Gene; Prefrontal cortex; Gene expression profiling; Computational biology; Gene regulatory network; Microarray; Candidate gene; Genetics; Gene expression; Psychology; Cognition; Psychiatry","score_opus":0.07877516742332039,"score_gpt":0.29752767029336497,"score_spread":0.21875250287004458,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009170866","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08918123,0.90246403,0.0006892617,0.000009998474,0.00020867198,0.0065465476,0.0005612795,0.000063045576,0.0002759121],"genre_scores_gemma":[0.5059774,0.49208075,0.0004006945,0.00047530426,0.00002259833,0.000518274,0.000059810638,0.00013250476,0.00033270725],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9962589,0.0010009949,0.0007255937,0.000927878,0.0007359384,0.00035065226],"domain_scores_gemma":[0.99704164,0.000989442,0.0010681679,0.00074840925,0.000062799,0.00008952912],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027451836,0.000436185,0.0022971416,0.0004925668,0.00008592692,0.0000688823,0.0010380367,0.00012615013,0.000046577476],"category_scores_gemma":[0.00043700426,0.0002211029,0.0006239956,0.002501763,0.0006863859,0.00018776889,0.00014722082,0.00027489828,0.0000016748463],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047882763,0.02163356,0.026376244,0.037818614,0.032785915,0.0003633662,0.0031965384,0.010338134,0.19791885,0.005486347,0.00081900024,0.65847516],"study_design_scores_gemma":[0.008901606,0.003981947,0.6728127,0.002146677,0.26952425,0.00006770626,0.00011741496,0.015185222,0.0014556365,0.000031469168,0.021869624,0.0039057136],"about_ca_topic_score_codex":0.000034015844,"about_ca_topic_score_gemma":0.000058220096,"teacher_disagreement_score":0.65456945,"about_ca_system_score_codex":0.000011303183,"about_ca_system_score_gemma":0.00010958312,"threshold_uncertainty_score":0.9016315},"labels":[],"label_agreement":null},{"id":"W2009439040","doi":"10.1159/000356549","title":"Targeting the Inflammatory Pathway as a Therapeutic Tool for Major Depression","year":2014,"lang":"en","type":"review","venue":"NeuroImmunoModulation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Major depressive disorder; Depression (economics); Inflammatory response; Medicine; Bipolar disorder; Inflammation; Psychology; Bioinformatics; Psychiatry; Immunology; Cognition; Biology","score_opus":0.04030343336484963,"score_gpt":0.30515567050813114,"score_spread":0.2648522371432815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009439040","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009455835,0.9923246,0.0016525554,0.000057393063,0.0010281405,0.003374545,0.00002212659,0.00022665197,0.0003684311],"genre_scores_gemma":[0.0116750235,0.98517585,0.000043416698,0.0008920388,0.00040375898,0.0007696326,0.0000924797,0.0001935685,0.00075424096],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972141,0.0006660397,0.00068803324,0.00071480003,0.00033097214,0.00038605422],"domain_scores_gemma":[0.99709517,0.0014757495,0.00064073305,0.0007174695,0.000036356803,0.000034494176],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004111768,0.0004505728,0.00066365843,0.00013227887,0.0005403028,0.00019595416,0.0006744454,0.00020604041,0.000038919847],"category_scores_gemma":[0.0010318116,0.00029242312,0.0004862677,0.00026041517,0.00008935311,0.00018874726,0.00011744881,0.00041661205,0.0002062917],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021972703,0.000027078613,0.0000022801999,0.0017955492,0.000011248406,0.0000023188034,0.00004223707,0.000050198032,0.0045426944,0.0010871673,0.00013529135,0.992282],"study_design_scores_gemma":[0.00032278654,0.00006664392,0.00005430116,0.0008414355,0.00007285526,0.000028824825,0.0000036534102,0.00073661504,0.0004684307,0.0006559937,0.99639744,0.00035103795],"about_ca_topic_score_codex":0.0000026105113,"about_ca_topic_score_gemma":4.215242e-7,"teacher_disagreement_score":0.99626213,"about_ca_system_score_codex":0.000050133844,"about_ca_system_score_gemma":0.00014773793,"threshold_uncertainty_score":0.9999528},"labels":[],"label_agreement":null},{"id":"W2010382787","doi":"10.1016/j.pnpbp.2013.05.006","title":"Combination of prenatal immune challenge and restraint stress affects prepulse inhibition and dopaminergic/GABAergic markers","year":2013,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Novartis Pharmaceuticals Canada; Fonds de Recherche du Québec - Santé; Novartis Pharma","keywords":"Prepulse inhibition; Dopaminergic; Prenatal stress; Striatum; Prefrontal cortex; Dopamine; Endocrinology; GABAergic; Internal medicine; Medicine; Schizophrenia (object-oriented programming); Neuroscience; Immune system; Dopamine receptor D2; Offspring; Psychology; Biology; Immunology; Pregnancy; Receptor; Psychiatry","score_opus":0.014768049468579743,"score_gpt":0.2741490767355101,"score_spread":0.25938102726693035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010382787","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904935,0.0045025293,0.000001987222,0.002945168,0.00057017885,0.0009927206,0.000020014339,0.00006360778,0.00041034713],"genre_scores_gemma":[0.99581283,0.0032917322,0.00010975172,0.00053240143,0.00004748612,0.00017476568,0.000008275548,0.000013160094,0.000009581983],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979886,0.00042889905,0.00036674438,0.00073275267,0.00012254051,0.0003604583],"domain_scores_gemma":[0.9991451,0.00037314757,0.00019485195,0.00013533834,0.000023293549,0.00012827969],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001954687,0.00026476977,0.00031034838,0.00017280228,0.00011421347,0.00003645385,0.00014367797,0.0002479563,0.000071733826],"category_scores_gemma":[0.000100841185,0.00020650456,0.00004439028,0.00022745434,0.0011913135,0.00021028653,0.00016490144,0.00038992165,0.0000021834478],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029040745,0.0033821634,0.8522151,0.0008556509,0.000038872517,0.00008557826,0.00039781965,0.000004534632,0.04725853,0.0108188735,0.00039125458,0.08164752],"study_design_scores_gemma":[0.005206721,0.0015242305,0.9829096,0.0000955339,0.0000102912845,0.00006359959,0.00014035664,0.00033092473,0.0028603582,0.006556716,0.000032213655,0.00026943473],"about_ca_topic_score_codex":0.0000044784692,"about_ca_topic_score_gemma":0.0000042789206,"teacher_disagreement_score":0.1306945,"about_ca_system_score_codex":0.0000066787156,"about_ca_system_score_gemma":0.000013601343,"threshold_uncertainty_score":0.84210116},"labels":[],"label_agreement":null},{"id":"W2010588199","doi":"10.1016/j.neuroscience.2011.11.011","title":"Altered object-in-place recognition memory, prepulse inhibition, and locomotor activity in the offspring of rats exposed to a viral mimetic during pregnancy","year":2011,"lang":"en","type":"article","venue":"Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":131,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Prepulse inhibition; Offspring; Psychology; Recognition memory; Startle response; Endocrinology; Pregnancy; Internal medicine; Developmental psychology; Neuroscience; Physiology; Schizophrenia (object-oriented programming); Medicine; Biology; Psychiatry; Cognition","score_opus":0.054399548137219776,"score_gpt":0.2548121676471687,"score_spread":0.2004126195099489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010588199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982796,0.000012437387,0.000040921273,0.000087830995,0.00015727815,0.00080482085,0.000006672619,0.000028954426,0.00058149995],"genre_scores_gemma":[0.9994745,0.000023494413,0.00007644161,0.00030040144,0.000009564498,0.00007205951,1.2429429e-7,0.000010281063,0.00003308387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982202,0.00030283656,0.00024209518,0.0006044543,0.00029437282,0.00033606318],"domain_scores_gemma":[0.9993852,0.00013332363,0.0001054015,0.00029221876,0.00001608724,0.000067818546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021130357,0.00014588148,0.00015252568,0.00023597172,0.00011378111,0.0000451727,0.00030717463,0.0000364407,0.000009951551],"category_scores_gemma":[0.0007434997,0.0001244312,0.000031356154,0.00079351367,0.00022571847,0.0004781691,0.00012219168,0.00017608218,0.000005029555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000099269324,0.0002194813,0.0016321219,0.00004431409,1.14330305e-7,0.000040286828,0.0031160854,0.000009251587,0.99248964,0.000012506619,0.0000020410766,0.0023348879],"study_design_scores_gemma":[0.00049735897,0.0001619982,0.22952102,0.00013744565,0.000001159163,0.000024117451,0.00010894111,0.00018551471,0.7690969,0.00015567782,0.0000018012138,0.000108027525],"about_ca_topic_score_codex":0.000055196946,"about_ca_topic_score_gemma":0.00009366246,"teacher_disagreement_score":0.2278889,"about_ca_system_score_codex":0.000023060527,"about_ca_system_score_gemma":0.000035377787,"threshold_uncertainty_score":0.5074157},"labels":[],"label_agreement":null},{"id":"W2011684192","doi":"10.1016/s0889-1591(02)00009-0","title":"Cytokines, stress, and depressive illness","year":2002,"lang":"en","type":"review","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":220,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Carleton University; Royal Ottawa Mental Health Centre","funders":"","keywords":"Cytokine; Neurochemical; Antidepressant; Psychoneuroimmunology; Proinflammatory cytokine; Depression (economics); Psychology; Sickness behavior; Tumor necrosis factor alpha; Immunology; Immune system; Major depressive disorder; Medicine; Inflammation; Psychiatry; Neuroscience; Cognition; Anxiety","score_opus":0.06121742803462278,"score_gpt":0.3200441787845443,"score_spread":0.2588267507499215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011684192","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0059630303,0.991759,0.0000025631389,0.000027263228,0.00019808591,0.000847475,0.00039136017,0.00009935687,0.0007118456],"genre_scores_gemma":[0.0026057246,0.99604475,0.000009547336,0.0001421166,0.000052950563,0.0001854343,0.000055284505,0.00006327604,0.000840883],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99781716,0.00053828437,0.00040034836,0.0006370292,0.00021305784,0.0003941005],"domain_scores_gemma":[0.9983447,0.00064061605,0.00023852337,0.00058872346,0.000021704689,0.0001657083],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001096822,0.0005331117,0.0010108291,0.00017519973,0.00051330955,0.00018322509,0.00046255515,0.00035169255,0.00016618033],"category_scores_gemma":[0.000437692,0.00043794038,0.00019044355,0.00031216696,0.0005001304,0.00019057147,0.0003992353,0.0007160001,0.000023287037],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000025368915,0.00016842994,0.00004873346,0.0021016046,0.0000068286186,0.00005402095,0.0001250852,1.0974061e-8,0.000088863584,0.00013505817,0.0004944773,0.9967744],"study_design_scores_gemma":[0.00051012717,0.000061633196,0.0013055169,0.0025402906,0.00026948604,0.00027651672,0.00007402547,9.501562e-7,0.0002469185,0.000036620244,0.9938725,0.0008053655],"about_ca_topic_score_codex":0.000087890156,"about_ca_topic_score_gemma":0.000012619789,"teacher_disagreement_score":0.995969,"about_ca_system_score_codex":0.000024705038,"about_ca_system_score_gemma":0.000049579357,"threshold_uncertainty_score":0.99980724},"labels":[],"label_agreement":null},{"id":"W2011845468","doi":"10.3389/fnins.2014.00416","title":"Cytokine variations and mood disorders: influence of social stressors and social support","year":2014,"lang":"en","type":"review","venue":"Frontiers in Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Mental Health Research Canada","funders":"","keywords":"Stressor; Mood disorders; Psychology; Social defeat; Depression (economics); Mood; Anhedonia; Cytokine; Social stress; Social connectedness; Developmental psychology; Clinical psychology; Neuroscience; Immunology; Medicine; Psychiatry; Social psychology; Anxiety; Pleasure","score_opus":0.02293037751869698,"score_gpt":0.2946379804167445,"score_spread":0.2717076028980475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011845468","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.032325618,0.92671555,0.009312164,0.0024796298,0.008050651,0.00893841,0.0029026777,0.0006977859,0.008577531],"genre_scores_gemma":[0.05085311,0.94823015,0.00026769322,0.0003030445,0.000066679495,0.0000682552,0.000007984613,0.000051972205,0.00015109715],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996896,0.00037324644,0.0006681214,0.0010733478,0.00046547514,0.0005237539],"domain_scores_gemma":[0.9989108,0.00020776251,0.00053122395,0.00023872439,0.000021160236,0.000090361646],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002979962,0.00042310945,0.0011949763,0.00050679233,0.00037798221,0.0001098646,0.00074189174,0.000251833,0.0000053824956],"category_scores_gemma":[0.00076406205,0.00040183577,0.00015110071,0.0010982632,0.0016174329,0.00035892992,0.0003357454,0.00045914494,0.0000017277092],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036118046,0.00050279946,0.0011422863,0.012578006,0.000013734083,0.00001692891,0.0032211796,0.000026543486,0.0010149772,0.01443545,0.0024087627,0.9646032],"study_design_scores_gemma":[0.0010533903,0.00025606356,0.008685819,0.000752554,0.00012977174,0.000034010412,0.00014593068,0.00054388493,0.000061630664,0.001974976,0.9852415,0.0011205188],"about_ca_topic_score_codex":0.000009694646,"about_ca_topic_score_gemma":0.000014862189,"teacher_disagreement_score":0.9828327,"about_ca_system_score_codex":0.000037529695,"about_ca_system_score_gemma":0.00018299693,"threshold_uncertainty_score":0.99984336},"labels":[],"label_agreement":null},{"id":"W2012028931","doi":"10.1586/14737175.8.1.1","title":"Fast-acting antidepressants: are we nearly there?","year":2007,"lang":"en","type":"editorial","venue":"Expert Review of Neurotherapeutics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Neuroscience; Medicine; Psychology","score_opus":0.057684727145477725,"score_gpt":0.3659947003450203,"score_spread":0.30830997319954256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012028931","genre_codex":"editorial","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000047790658,0.2993926,0.00037832942,0.0013848986,0.6915335,0.001371301,0.00019044577,0.0002606623,0.0054404554],"genre_scores_gemma":[0.000090525406,0.73628104,0.00023415244,0.009652914,0.2527531,0.0000399863,0.0000126484065,0.00022726745,0.00070835],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948671,0.0005187956,0.0011106587,0.0010456354,0.0017788603,0.0006789442],"domain_scores_gemma":[0.99488246,0.0022682932,0.0012794519,0.0011935668,0.0002306288,0.00014559181],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046307867,0.00073571544,0.0013183985,0.00018360621,0.00015480389,0.000093865034,0.0013725347,0.00056866,0.00031934577],"category_scores_gemma":[0.0022576374,0.00062465976,0.0005389241,0.00061062933,0.00031016447,0.00019080218,0.00017390029,0.0013957304,0.000068941736],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003920764,0.00018125681,0.0000029399216,0.00534236,0.000028520797,0.000076322955,0.00022567925,6.4820284e-7,0.011927041,0.000017911354,0.91294575,0.069212385],"study_design_scores_gemma":[0.0003807102,0.00012586359,0.0000069997623,0.012449297,0.000027290132,0.0000072819366,0.00006591863,0.000009113773,0.01711904,0.000024997827,0.96924406,0.00053944625],"about_ca_topic_score_codex":0.000017935747,"about_ca_topic_score_gemma":0.0000032491203,"teacher_disagreement_score":0.4387804,"about_ca_system_score_codex":0.000046855614,"about_ca_system_score_gemma":0.00021121716,"threshold_uncertainty_score":0.9996205},"labels":[],"label_agreement":null},{"id":"W2012110465","doi":"10.2174/156720511795255982","title":"Does a Pro-Inflammatory Process Precede Alzheimers Disease and Mild Cognitive Impairment?","year":2011,"lang":"en","type":"article","venue":"Current Alzheimer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Alzheimer's disease; Cognitive impairment; Disease; Cognition; Medicine; Psychology; Neuroscience; Pathology","score_opus":0.2350679501944421,"score_gpt":0.4125679148927063,"score_spread":0.17749996469826418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012110465","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98617935,0.0063679293,0.0000083726845,0.0003179881,0.0004814806,0.0029822872,0.000078999044,0.00021559464,0.0033679837],"genre_scores_gemma":[0.9984784,0.00055119395,0.0000159876,0.000060860115,0.00011746949,0.00062416284,0.000008960943,0.00005137823,0.00009158247],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996177,0.0005074785,0.0002964121,0.0010215509,0.0009913566,0.001006162],"domain_scores_gemma":[0.99832857,0.00033618134,0.00008355588,0.00035488297,0.00020670105,0.00069010025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000586564,0.0003033559,0.00021127444,0.00036246623,0.0004921388,0.00013329259,0.00052761764,0.00007084844,0.0004125178],"category_scores_gemma":[0.00058655586,0.00020227066,0.000089345085,0.0006069687,0.0012527194,0.00051056704,0.00033859495,0.0006588314,0.0002623159],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021415949,0.017417781,0.3154068,0.0043480615,0.002396814,0.00066443393,0.11095801,0.000004191235,0.026492655,0.02005358,0.01812763,0.46271408],"study_design_scores_gemma":[0.008710669,0.001205647,0.22064267,0.0016090494,0.00065821386,0.0000196998,0.008256605,0.000971373,0.72367114,0.026020203,0.005492283,0.002742438],"about_ca_topic_score_codex":0.000011689629,"about_ca_topic_score_gemma":0.000012285176,"teacher_disagreement_score":0.6971785,"about_ca_system_score_codex":0.000019627454,"about_ca_system_score_gemma":0.00028738668,"threshold_uncertainty_score":0.8248358},"labels":[],"label_agreement":null},{"id":"W2012695716","doi":"10.1016/j.mad.2006.01.009","title":"Inflammatory/immune responses in ageing: Relevant factors and putative targets for intervention","year":2006,"lang":"en","type":"article","venue":"Mechanisms of Ageing and Development","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Ageing; Immune system; Immunology; Inflammation; Biology; Senescence; Medicine; Gerontology; Computational biology; Genetics","score_opus":0.02078742733953059,"score_gpt":0.2530395207887257,"score_spread":0.23225209344919512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012695716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9768321,0.00016541574,0.022481138,0.00006034387,0.00008024566,0.00028682683,0.000006357473,0.000033050997,0.00005453053],"genre_scores_gemma":[0.9928111,0.000018067025,0.0068996237,0.00002927386,0.0000041572625,0.000028744313,0.0000062410863,0.000012463617,0.00019032319],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989754,0.00007023003,0.0003505556,0.00027455876,0.00013325142,0.00019601302],"domain_scores_gemma":[0.9995047,0.00024841732,0.00013101738,0.00006397584,0.000020372396,0.000031544605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031810903,0.00013849846,0.00018422467,0.00018597938,0.000118700205,0.000032297936,0.00006839899,0.000050225473,0.0000042887314],"category_scores_gemma":[0.00030176202,0.000121189536,0.00003123188,0.00008658932,0.000052521147,0.00010829787,0.00006783786,0.00006214288,8.043054e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003513574,0.00018975064,0.0016941763,0.00030594895,0.000012580964,0.00008171799,0.00460309,0.000036153757,0.9638102,0.013630577,0.000024593626,0.015259852],"study_design_scores_gemma":[0.0009304486,0.00010495158,0.13348371,0.00011511944,0.000002122321,0.000002500153,0.00084640516,0.00007988764,0.8475762,0.01628474,0.00041708627,0.00015682366],"about_ca_topic_score_codex":0.000061628394,"about_ca_topic_score_gemma":0.00005609434,"teacher_disagreement_score":0.13178954,"about_ca_system_score_codex":0.000027584667,"about_ca_system_score_gemma":0.000031121286,"threshold_uncertainty_score":0.4941966},"labels":[],"label_agreement":null},{"id":"W2013369041","doi":"10.1016/j.physbeh.2010.09.018","title":"Increased plasma d-lactic acid associated with impaired memory in rats","year":2010,"lang":"en","type":"article","venue":"Physiology & Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Wilfrid Laurier University","funders":"","keywords":"Lactic acid; Lactic acidosis; Fermentation; Lactic acid fermentation; Internal medicine; Endocrinology; Carbohydrate; Biology; Chemistry; Biochemistry; Medicine; Bacteria","score_opus":0.020541832037967226,"score_gpt":0.259553977393448,"score_spread":0.23901214535548077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013369041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99869525,0.0000073619894,2.7276837e-7,0.00008901524,0.00034698393,0.00033055784,0.00001846331,0.00014863766,0.0003634473],"genre_scores_gemma":[0.9990582,0.0000019230727,0.000032238073,0.00053378846,0.00004651282,0.00015699373,0.000017404182,0.000029711278,0.000123226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998471,0.00021049676,0.00019502669,0.000506264,0.00015603955,0.0004611361],"domain_scores_gemma":[0.9991467,0.0002617254,0.00011979265,0.00033824067,0.000026110953,0.00010743535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109495384,0.00021297112,0.00027878728,0.0001233877,0.00011306972,0.000019526828,0.00031113296,0.00017940771,0.0002923809],"category_scores_gemma":[0.000514771,0.0001767545,0.00006134996,0.0003560987,0.00035388893,0.00016615308,0.000060320337,0.00054069504,0.000102524915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015268603,0.00062149245,0.0059543783,0.0000022937966,0.0000030520787,0.000060506187,0.00013147117,9.201103e-7,0.99175835,0.00003568566,0.00009521847,0.0011839658],"study_design_scores_gemma":[0.0011371054,0.00012411943,0.48869434,0.0000063617786,0.000012639227,0.000010150621,0.00004045544,0.000034945213,0.509724,0.00003796743,0.000019352055,0.00015851909],"about_ca_topic_score_codex":0.000079402,"about_ca_topic_score_gemma":0.0006163646,"teacher_disagreement_score":0.48273996,"about_ca_system_score_codex":0.000032365373,"about_ca_system_score_gemma":0.00009743509,"threshold_uncertainty_score":0.72078395},"labels":[],"label_agreement":null},{"id":"W2014446321","doi":"10.1038/nrneurol.2013.93","title":"A link between microbial infection and cognition?","year":2013,"lang":"en","type":"review","venue":"Nature Reviews Neurology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Hospital; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Cognition; Cohort; Cohort study; Ethnic group; Link (geometry); Intensive care medicine; Immunology; Internal medicine; Psychiatry","score_opus":0.05885370607291726,"score_gpt":0.34781493133345054,"score_spread":0.28896122526053325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014446321","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000031901796,0.9950236,0.0000072894363,0.00046724197,0.00081686216,0.002531787,0.00005158299,0.000110542605,0.0009591664],"genre_scores_gemma":[0.000019615469,0.9942716,0.0000314186,0.003907306,0.001233232,0.00025359675,0.00006630836,0.0000698432,0.00014710776],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99601525,0.0015791575,0.0007783928,0.0010605155,0.00013604613,0.00043066381],"domain_scores_gemma":[0.9979725,0.0008193648,0.0006116901,0.00042844928,0.000029778796,0.00013822013],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0002481858,0.0006044838,0.002252607,0.0003138474,0.00014384498,0.00007602065,0.000333363,0.0018419918,0.00016137255],"category_scores_gemma":[0.0013571228,0.00044788423,0.0005128368,0.0005673997,0.00022583526,0.0001233859,0.0001891633,0.003179502,0.0011028098],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000019496576,0.000012413464,0.0000027121218,0.00626791,0.000010151513,0.000010837255,0.0000037447037,3.640041e-9,0.00003570375,0.00011392089,0.0049627563,0.9885779],"study_design_scores_gemma":[0.00017842397,0.00012761852,0.000021979746,0.0012737202,0.00026301874,0.00035057054,4.0774193e-8,2.0793716e-7,0.000016547361,0.00023831478,0.99718964,0.00033991135],"about_ca_topic_score_codex":0.0000032555827,"about_ca_topic_score_gemma":0.0000044959097,"teacher_disagreement_score":0.9922269,"about_ca_system_score_codex":0.000013488001,"about_ca_system_score_gemma":0.00007139809,"threshold_uncertainty_score":0.9997973},"labels":[],"label_agreement":null},{"id":"W2015172696","doi":"10.4088/pcc.14l01695","title":"Nabilone for the Treatment of Dementia-Associated Sexual Disinhibition","year":2015,"lang":"en","type":"article","venue":"The Primary Care Companion For CNS Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Dementia; Disinhibition; Psychological intervention; Affect (linguistics); Psychiatry; Psychology; Institutionalisation; Medicine; Clinical psychology; Internal medicine; Disease","score_opus":0.05185389231880671,"score_gpt":0.2781513253328916,"score_spread":0.2262974330140849,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015172696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9767443,0.0030669977,0.009087192,0.003734213,0.00085995276,0.004385291,0.0005773991,0.00017572018,0.0013689125],"genre_scores_gemma":[0.99853534,0.00014923846,0.00008487691,0.00044423706,0.000048653787,0.00035132832,0.0001908074,0.00003272504,0.00016282687],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99872774,0.00011769323,0.0002627553,0.000303909,0.0002743188,0.00031358787],"domain_scores_gemma":[0.99855435,0.0007451222,0.00017659878,0.00035493597,0.00010962532,0.000059359372],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016792085,0.00019872477,0.00023083917,0.000046777426,0.00038412242,0.000040850515,0.0003432117,0.00005321871,0.000008753291],"category_scores_gemma":[0.00019171955,0.000117985626,0.0002102846,0.00021941579,0.00025752425,0.0000983084,0.000042948748,0.00004870847,0.0000050094577],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0072525693,0.01467547,0.008372685,0.001178733,0.0015682935,0.0000021779272,0.11597573,0.012852944,0.1464256,0.04517334,0.097411536,0.5491109],"study_design_scores_gemma":[0.07159496,0.024376981,0.049428523,0.00016975318,0.0021887312,0.000013176794,0.12584399,0.0170066,0.15378089,0.056361467,0.4960332,0.0032017375],"about_ca_topic_score_codex":0.00007345344,"about_ca_topic_score_gemma":0.00026057925,"teacher_disagreement_score":0.54590917,"about_ca_system_score_codex":0.00019992971,"about_ca_system_score_gemma":0.00010606044,"threshold_uncertainty_score":0.48113143},"labels":[],"label_agreement":null},{"id":"W2015264407","doi":"10.1111/nmo.12540","title":"Vagotomy prevents the effect of probiotics on caspase activity in a model of postmyocardial infarction depression","year":2015,"lang":"en","type":"article","venue":"Neurogastroenterology & Motility","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lallemand (Canada); Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Vagus nerve; Vagotomy; Medicine; Myocardial infarction; Depression (economics); Infarction; Amygdala; Apoptosis; Internal medicine; Anesthesia; Endocrinology; Pharmacology; Biology; Biochemistry","score_opus":0.02852012134819443,"score_gpt":0.27503775495725385,"score_spread":0.24651763360905943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015264407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99858737,0.0000024365527,0.00011949561,0.00020371094,0.00021165042,0.00071968476,0.000033119002,0.00002336143,0.00009915616],"genre_scores_gemma":[0.9996672,0.000002233371,0.000016894794,0.0002620109,0.000011685605,0.000022769414,0.0000012912859,0.00001096038,0.000004925883],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974705,0.0013022883,0.00026529186,0.0004037076,0.0002772936,0.0002809064],"domain_scores_gemma":[0.9989993,0.0002523388,0.00019833032,0.0004495788,0.000026809372,0.00007364427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043805584,0.00017157207,0.00030748802,0.00009739317,0.00003537922,0.0000052838227,0.00028927613,0.00009054556,0.000002306951],"category_scores_gemma":[0.00072060747,0.00012217768,0.000114342045,0.00015257065,0.00028871073,0.00011108261,0.00015519922,0.00034414034,0.000002044343],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024800987,0.0007464107,0.5895225,0.000060036342,0.000009755534,0.000005174874,0.00025878084,0.024561824,0.38084128,0.000008144434,0.00007178078,0.0014342522],"study_design_scores_gemma":[0.0028781565,0.0030396015,0.5782231,0.000018224979,0.000014990575,0.000010382688,0.0000065319273,0.023766775,0.39191845,0.00009667315,0.000003934348,0.000023164452],"about_ca_topic_score_codex":0.000038866554,"about_ca_topic_score_gemma":0.000032964996,"teacher_disagreement_score":0.011299345,"about_ca_system_score_codex":0.0000349423,"about_ca_system_score_gemma":0.00003067134,"threshold_uncertainty_score":0.49822608},"labels":[],"label_agreement":null},{"id":"W2015725986","doi":"10.1038/mp.2013.137","title":"Role of brain transmigrating neutrophils in depression-like behavior during systemic infection","year":2013,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":97,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; McGill University; Douglas Mental Health University Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Sickness behavior; Leptin; Immune system; Lipopolysaccharide; Inflammation; Systemic inflammation; Immunology; Mood; Hormone; Neuroscience; Psychology; Medicine; Endocrinology; Obesity; Psychiatry","score_opus":0.005118428082851189,"score_gpt":0.22317358776091425,"score_spread":0.21805515967806308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015725986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978897,0.00045580932,0.00016039473,0.0001450537,0.00028483852,0.0005499538,0.0000026221976,0.0000718714,0.00043974473],"genre_scores_gemma":[0.99924505,0.000013007342,0.0002054905,0.00031523092,0.000024436149,0.00014113242,0.0000013427102,0.000029173252,0.000025126703],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986594,0.0001465977,0.00033973771,0.00037162725,0.00020922782,0.00027346006],"domain_scores_gemma":[0.9994978,0.000029618466,0.000114752955,0.00027676794,0.000016479995,0.00006462986],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006089172,0.00015810832,0.00017382856,0.00019383409,0.000070122376,0.000032227603,0.00017406819,0.00008557622,0.00005763716],"category_scores_gemma":[0.000043954406,0.00015595809,0.0001129018,0.00038237168,0.00004422292,0.0001679577,0.00003070428,0.00019275748,0.000032054573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009207498,0.00014988432,0.07140289,0.00007775742,0.0000019095364,0.0000055118157,0.00013669489,0.0002380553,0.9266758,0.00017916811,0.000025697578,0.0010974156],"study_design_scores_gemma":[0.0012288262,0.00005853928,0.43483007,0.00023610871,0.000009224442,0.000083888655,0.00022348893,0.00035273068,0.5618615,0.0008249408,0.000019089268,0.00027159246],"about_ca_topic_score_codex":0.00027103198,"about_ca_topic_score_gemma":0.000072044386,"teacher_disagreement_score":0.3648143,"about_ca_system_score_codex":0.000020173025,"about_ca_system_score_gemma":0.000033848493,"threshold_uncertainty_score":0.63597864},"labels":[],"label_agreement":null},{"id":"W2015858267","doi":"10.1016/j.biopsych.2014.11.024","title":"Elevated Monoamine Oxidase-A Distribution Volume in Borderline Personality Disorder Is Associated With Severity Across Mood Symptoms, Suicidality, and Cognition","year":2014,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research; American Psychiatric Institute for Research and Education","keywords":"Borderline personality disorder; Psychology; Internal medicine; Anterior cingulate cortex; Mood; Prefrontal cortex; Clinical psychology; Psychiatry; Medicine; Cognition","score_opus":0.02120349506586828,"score_gpt":0.27162844506045614,"score_spread":0.25042494999458786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015858267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953842,0.00007151694,0.0006352878,0.0021956337,0.00010581111,0.0003443832,0.00083377596,0.00017579942,0.00025359384],"genre_scores_gemma":[0.997417,0.000035772904,0.000045188754,0.0018251551,0.00004794165,0.000027069602,0.00052857277,0.000014020483,0.00005929605],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.997712,0.00042960237,0.0003397255,0.00075068796,0.0002328874,0.0005351062],"domain_scores_gemma":[0.99925166,0.00019312422,0.00016087283,0.000206365,0.000057879366,0.00013010875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043160727,0.000284425,0.0003352008,0.00002876035,0.0002374312,0.000066991444,0.00018428377,0.00032191788,0.00010562854],"category_scores_gemma":[0.0008061327,0.00021229064,0.00006246482,0.0005108633,0.0004387258,0.00013594591,0.000091054244,0.00035186653,0.000017170649],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039798763,0.0013496747,0.98823464,0.00003031738,0.000018079376,0.0000022221936,0.00009382584,0.000003975132,0.006747092,0.0011641338,0.00032827703,0.0016297514],"study_design_scores_gemma":[0.002678335,0.0005226716,0.99028033,0.00003640723,0.000009243057,0.000007377762,0.00011166254,0.0017848245,0.00056870334,0.0028601112,0.00077600114,0.0003643521],"about_ca_topic_score_codex":0.0001397994,"about_ca_topic_score_gemma":0.00095902855,"teacher_disagreement_score":0.006178389,"about_ca_system_score_codex":0.000041867355,"about_ca_system_score_gemma":0.000031259024,"threshold_uncertainty_score":0.86569613},"labels":[],"label_agreement":null},{"id":"W2017719663","doi":"10.4236/abb.2012.324072","title":"&amp;lt;i&amp;gt;In vivo&amp;lt;/i&amp;gt; immunomodulatory effects of antipsychotics on inflammatory mediators: A review","year":2012,"lang":"en","type":"review","venue":"Advances in Bioscience and Biotechnology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institut universitaire en santé mentale de Montréal","funders":"","keywords":"Antipsychotic; Clozapine; Cytokine; Tumor necrosis factor alpha; Schizophrenia (object-oriented programming); Interleukin; Medicine; Pharmacology; Receptor; Internal medicine; Immunology; Psychiatry","score_opus":0.02795078010364414,"score_gpt":0.3214903518592888,"score_spread":0.29353957175564466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017719663","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008251888,0.98752254,0.00008188269,0.00021534055,0.0016446743,0.0017907784,0.00005741805,0.00018003283,0.000255432],"genre_scores_gemma":[0.0027635358,0.99534416,0.0008116359,0.0006481705,0.00007791491,0.00015462148,0.000013300612,0.00006843108,0.00011820834],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99400777,0.00052857446,0.0016067204,0.0018023971,0.0007113174,0.0013432378],"domain_scores_gemma":[0.9956205,0.0011951802,0.0011868579,0.0017576503,0.000045148372,0.00019467852],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0010023683,0.001017137,0.0025396508,0.0016938125,0.00017447893,0.00003942385,0.0020493742,0.0013540752,0.000051965148],"category_scores_gemma":[0.0025854914,0.0008158654,0.00036086788,0.0036577564,0.0031567002,0.00062277185,0.0004886045,0.0013103358,0.00018568477],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038831862,0.0005647046,0.00009847888,0.03503434,0.000016472928,0.000025914147,0.000111149035,0.0000013793294,0.042083807,0.0048631597,0.0002727114,0.9168891],"study_design_scores_gemma":[0.00044712608,0.00014838182,0.00005155648,0.02754013,0.00008258633,0.000084509644,0.000005240519,5.898167e-7,0.003118458,0.00046061986,0.9672268,0.00083399273],"about_ca_topic_score_codex":0.0000037830312,"about_ca_topic_score_gemma":0.00020942334,"teacher_disagreement_score":0.9669541,"about_ca_system_score_codex":0.00016078737,"about_ca_system_score_gemma":0.00022463285,"threshold_uncertainty_score":0.99994236},"labels":[],"label_agreement":null},{"id":"W2018711807","doi":"10.1016/s0165-1781(00)00184-0","title":"Effects of repeated fluoxetine and citalopram administration on cytokine release in C57BL/6 mice","year":2000,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":77,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Fluoxetine; Citalopram; Splenocyte; Cytokine; Pharmacology; Serotonin reuptake inhibitor; Serotonin; Reuptake inhibitor; Medicine; Endocrinology; Internal medicine; Immune system; Immunology; Receptor","score_opus":0.028401634401070193,"score_gpt":0.3352218104730386,"score_spread":0.30682017607196843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018711807","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877189,0.0001907098,0.0000014099904,0.0023282322,0.00008334182,0.00045761536,0.000008197337,0.000033504846,0.009178117],"genre_scores_gemma":[0.9983723,0.00021096482,0.00011484154,0.00023968866,0.00005357729,0.000028227898,0.000003735592,0.000016590571,0.0009600808],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980727,0.00039951727,0.0002385203,0.00045702257,0.00047907035,0.00035316162],"domain_scores_gemma":[0.9990407,0.0005316261,0.000035307494,0.00024738218,0.000032059943,0.00011292451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004028674,0.00011397264,0.00014272888,0.00026625904,0.000097560805,0.00003537805,0.00019645964,0.00008079826,0.00016916834],"category_scores_gemma":[0.00076407875,0.00010611966,0.000031419186,0.0009020972,0.00020429649,0.000090209265,0.00002243921,0.0003815663,0.00008195735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004513286,0.0028212364,0.012472367,0.00080067833,0.000009244959,0.00014043954,0.00047035638,0.000025746094,0.9262798,0.003806691,0.004493818,0.044166375],"study_design_scores_gemma":[0.0055892677,0.0035413373,0.21251503,0.00043775237,0.000006390892,0.00004101689,0.0002015232,0.0006583245,0.7693024,0.004039489,0.0032619783,0.0004054793],"about_ca_topic_score_codex":0.000053442862,"about_ca_topic_score_gemma":0.00006549903,"teacher_disagreement_score":0.20004265,"about_ca_system_score_codex":0.000018290246,"about_ca_system_score_gemma":0.000100878315,"threshold_uncertainty_score":0.4327434},"labels":[],"label_agreement":null},{"id":"W2018764785","doi":"10.3899/jrheum.110900","title":"Psychiatric Disorders in Patients with Immune-Mediated Inflammatory Diseases: Prevalence, Association with Disease Activity, and Overall Patient Well-being","year":2011,"lang":"en","type":"review","venue":"Journal of Rheumatology Supplement","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba; SKiN Health; University of British Columbia; Manitoba Health; St. Boniface Hospital","funders":"LEO Pharma; Michael Smith Health Research BC; Crohn's and Colitis Foundation; Amgen; Crohn's and Colitis Foundation of Canada; AstraZeneca; Child and Family Research Institute; Canadian Institutes of Health Research; Abbott Canada; AstraZeneca Canada; Janssen Canada; Amgen Canada","keywords":"Medicine; Depression (economics); Disease; Anxiety; Cohort; Psychiatry; Affect (linguistics); Immunology; Clinical psychology; Internal medicine","score_opus":0.0062359490882168325,"score_gpt":0.23295347679825884,"score_spread":0.226717527710042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018764785","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4800085,0.51648426,0.000017285067,0.00019622062,0.0005863762,0.0023781126,0.00021264375,0.000033631113,0.00008294419],"genre_scores_gemma":[0.1298563,0.8698608,0.00005098706,0.00004112909,0.000008833793,0.00007350939,0.00003330393,0.00005918024,0.000015944928],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9962523,0.00071614905,0.0012253313,0.00052467076,0.00072251976,0.0005590541],"domain_scores_gemma":[0.9958167,0.00053355517,0.002962668,0.00030464955,0.00008693941,0.00029550417],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024452625,0.00055978156,0.0014423708,0.00077428017,0.00012806775,0.000056337736,0.00040649076,0.00019151425,0.00014393129],"category_scores_gemma":[0.00027940638,0.00038374125,0.00025040502,0.00040851007,0.00014101587,0.00044181224,0.00014822543,0.00067993294,0.000009596899],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011259625,0.0014593783,0.9496222,0.00851244,0.00023892274,0.000031610936,0.0003441183,0.0000057630186,2.2594476e-7,0.00021695156,0.000489295,0.037953112],"study_design_scores_gemma":[0.021232298,0.005478334,0.55478853,0.022935992,0.0024213188,0.00013289905,0.00015154222,0.000019954048,0.000005071498,0.0008459555,0.38931626,0.0026718148],"about_ca_topic_score_codex":0.000021818503,"about_ca_topic_score_gemma":0.00006143809,"teacher_disagreement_score":0.39483368,"about_ca_system_score_codex":0.0003342788,"about_ca_system_score_gemma":0.0005438968,"threshold_uncertainty_score":0.9998615},"labels":[],"label_agreement":null},{"id":"W2018933100","doi":"10.1055/s-0029-1202263","title":"Imbalance between Pro- and Anti-inflammatory Cytokines, and between Th1 and Th2 Cytokines in Depressed Patients: The Effect of Electroacupuncture or Fluoxetine Treatment","year":2009,"lang":"en","type":"article","venue":"Pharmacopsychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":190,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"","keywords":"Proinflammatory cytokine; Electroacupuncture; Fluoxetine; Cytokine; Medicine; Tumor necrosis factor alpha; Placebo; Internal medicine; Endocrinology; Acupuncture; Pharmacology; Immunology; Inflammation; Receptor; Serotonin; Pathology","score_opus":0.01180854497594369,"score_gpt":0.27583235842079123,"score_spread":0.26402381344484754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018933100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961373,0.0015092377,0.0000055352193,0.0009765382,0.00009394046,0.0010499659,0.00006558364,0.0000537287,0.0001081621],"genre_scores_gemma":[0.9986001,0.00069700816,0.00003765218,0.00039023685,0.00018595881,0.00003315758,0.0000100900825,0.000021943562,0.000023835346],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99832267,0.00025097985,0.00033005563,0.00052145956,0.00021236327,0.00036246722],"domain_scores_gemma":[0.9991044,0.00039802658,0.00016294651,0.00020964317,0.00001627839,0.00010874589],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016610911,0.0003692166,0.00047917894,0.00010738015,0.00014362489,0.00004660264,0.00019152698,0.00008418353,0.000009013499],"category_scores_gemma":[0.000085690604,0.00019626938,0.00005054427,0.00029917894,0.000181583,0.00017220757,0.000053861684,0.00020548457,9.42773e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044671237,0.00007876582,0.90965104,0.00012865545,0.000024534855,0.0000045151737,0.00019913002,0.0000031171421,0.067280106,0.0000123798645,0.00018479397,0.021986252],"study_design_scores_gemma":[0.005326647,0.00082642405,0.8151196,0.000046783945,0.00007763862,0.000006292897,0.0000110999035,0.000035635105,0.17765789,0.00011145825,0.00057226344,0.00020823913],"about_ca_topic_score_codex":0.000014998977,"about_ca_topic_score_gemma":0.000008769684,"teacher_disagreement_score":0.11037778,"about_ca_system_score_codex":0.00001919147,"about_ca_system_score_gemma":0.000032272557,"threshold_uncertainty_score":0.8003633},"labels":[],"label_agreement":null},{"id":"W2019135818","doi":"10.1016/j.genhosppsych.2015.01.005","title":"New insights into the neurobiological mechanisms of major depressive disorders","year":2015,"lang":"en","type":"review","venue":"General Hospital Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Major depressive disorder; Neuroimaging; Amygdala; Psychology; Neuroscience; Mechanism (biology); Psychiatry; Clinical psychology","score_opus":0.022895523803702925,"score_gpt":0.2862595714919853,"score_spread":0.26336404768828237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019135818","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005559625,0.98986715,0.0004902343,0.00057743,0.0053787166,0.0012994519,0.000030781324,0.000114302806,0.0016859403],"genre_scores_gemma":[0.0006881162,0.995633,0.0013292445,0.0005882456,0.0006412005,0.00008960818,0.00003747891,0.0000968927,0.0008961944],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996783,0.00044636775,0.0007476154,0.0010564941,0.00046435112,0.0005021722],"domain_scores_gemma":[0.99805105,0.0001404266,0.0006288621,0.00088838424,0.000034396682,0.00025689704],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010387869,0.0007139868,0.0012440381,0.00015330239,0.00020613491,0.000067295514,0.0017588137,0.0004805814,0.00007026462],"category_scores_gemma":[0.00015758416,0.0004061022,0.00084485265,0.0007069597,0.00029390698,0.00012741146,0.0004472847,0.00067883125,0.00016787555],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029713947,0.0004380577,0.000008300258,0.0018982098,0.000102230784,0.000009814793,0.000505292,0.000011546044,0.00011663928,0.094407395,0.03730873,0.8651641],"study_design_scores_gemma":[0.0006295087,0.0006433876,0.00001617825,0.0006378408,0.00019417913,0.000012705978,0.00006592346,0.00000634111,0.00010713505,0.17576459,0.8211555,0.00076669885],"about_ca_topic_score_codex":0.00006670144,"about_ca_topic_score_gemma":0.000056635665,"teacher_disagreement_score":0.86439735,"about_ca_system_score_codex":0.000038040682,"about_ca_system_score_gemma":0.00063041045,"threshold_uncertainty_score":0.99983907},"labels":[],"label_agreement":null},{"id":"W2019315586","doi":"10.1021/tx050095o","title":"A Comparison of the Covalent Binding of Clozapine, Procainamide, and Vesnarinone to Human Neutrophils in Vitro and Rat Tissues in Vitro and in Vivo","year":2005,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"In vitro; Procainamide; In vivo; Clozapine; Pharmacology; Chemistry; Covalent bond; Biochemistry; Internal medicine; Medicine; Biology; Schizophrenia (object-oriented programming); Biotechnology","score_opus":0.10609939632704743,"score_gpt":0.4203702081701297,"score_spread":0.31427081184308225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019315586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99660736,0.00034511348,4.031211e-7,0.0022368627,0.000013695321,0.0006083317,0.000005116885,0.000004062231,0.00017904452],"genre_scores_gemma":[0.99956083,0.00011744815,0.00010977309,0.00010863774,0.000011758961,0.000055754103,5.3187335e-7,0.000008873734,0.000026395628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99812275,0.00033697384,0.00040814097,0.00041434064,0.00024692123,0.00047085018],"domain_scores_gemma":[0.9989311,0.00074241334,0.000053119744,0.0001589695,0.000019766483,0.00009462737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062874623,0.000110095316,0.00038003284,0.0004937831,0.00003349953,0.00001486487,0.0002558907,0.00013423753,0.000007200341],"category_scores_gemma":[0.0011718217,0.00009365649,0.000014371756,0.000818269,0.000823923,0.00006618409,0.00046625588,0.0005375209,4.9679835e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006722205,0.0003812331,0.010559449,0.00011269562,7.456735e-7,0.00001285035,0.0009518884,0.00001203602,0.9842403,0.0002146449,0.000028825312,0.0028131176],"study_design_scores_gemma":[0.0015615532,0.00015476104,0.013599644,0.000075160286,5.3347947e-7,0.000005313056,0.00023953535,0.0005060262,0.98318046,0.00041183628,0.00018751991,0.00007764174],"about_ca_topic_score_codex":0.00007308099,"about_ca_topic_score_gemma":0.00035908754,"teacher_disagreement_score":0.0030401952,"about_ca_system_score_codex":0.00011483675,"about_ca_system_score_gemma":0.000046713438,"threshold_uncertainty_score":0.3819201},"labels":[],"label_agreement":null},{"id":"W2019640877","doi":"10.1186/1751-0759-3-3","title":"Allergies and major depression: a longitudinal community study","year":2009,"lang":"en","type":"article","venue":"BioPsychoSocial Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale","keywords":"Allergy; Depression (economics); Medicine; CIDI; Incidence (geometry); Longitudinal study; Environmental health; Cohort; Hazard ratio; Cohort study; Demography; Population; Confidence interval; Internal medicine; Immunology; Pathology; National Comorbidity Survey","score_opus":0.05735928973802404,"score_gpt":0.33594736867834407,"score_spread":0.27858807894032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019640877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97967565,0.0003221659,0.000024903895,0.0047827926,0.00033641534,0.00033766197,0.000002330745,0.00012366955,0.014394411],"genre_scores_gemma":[0.9967155,0.00006259749,0.000025803389,0.0026417654,0.00030345042,0.000009402926,0.0000010064781,0.00000829454,0.00023217865],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987453,0.00026721676,0.00019130675,0.00027086923,0.00030255044,0.00022276101],"domain_scores_gemma":[0.99933654,0.00019369314,0.00006976637,0.00026246937,0.000020616397,0.00011689884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024187383,0.00015621186,0.00022641972,0.00007639648,0.00049762195,0.000023996836,0.00026150205,0.000058783524,0.000087002365],"category_scores_gemma":[0.00045547605,0.000116472045,0.000026496564,0.00028603175,0.00031389427,0.00008479032,0.00004841204,0.0002857663,0.000012379006],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017845569,0.007062118,0.09758243,0.00007627081,0.00007736755,0.00031439547,0.055262897,8.532529e-7,0.53844327,0.005279797,0.06733173,0.22678433],"study_design_scores_gemma":[0.004009356,0.0015079231,0.9795676,0.0000684648,0.000018033792,0.000021784139,0.006110017,0.0000040270306,0.0016719601,0.0036460378,0.003158809,0.00021602446],"about_ca_topic_score_codex":0.000096568205,"about_ca_topic_score_gemma":0.00004866347,"teacher_disagreement_score":0.8819851,"about_ca_system_score_codex":0.000012124978,"about_ca_system_score_gemma":0.000011660606,"threshold_uncertainty_score":0.4749592},"labels":[],"label_agreement":null},{"id":"W2020066927","doi":"10.1159/000026457","title":"Central Monoamine Activity following Acute and Repeated Systemic Interleukin-2 Administration","year":2000,"lang":"en","type":"article","venue":"NeuroImmunoModulation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Carleton University","funders":"","keywords":"Monoamine neurotransmitter; Endocrinology; Internal medicine; Dopamine; Medicine; Serotonin; Hippocampus; Prefrontal cortex; Amygdala; Norepinephrine; Locus coeruleus; Neuroscience; Psychology; Central nervous system; Receptor; Cognition","score_opus":0.016240573613129566,"score_gpt":0.25166556277399244,"score_spread":0.23542498916086288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020066927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99780256,0.00003138446,0.00026198194,0.00017279653,0.00025098515,0.00029828525,0.0000068644886,0.00017941688,0.0009957415],"genre_scores_gemma":[0.99913603,0.000064051565,0.000023338005,0.00014788208,0.00003286048,0.000010119396,0.000012685835,0.000021047039,0.00055198546],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987864,0.00013771506,0.00021525736,0.00043200114,0.00017973025,0.0002489226],"domain_scores_gemma":[0.99953717,0.0000661828,0.00008074672,0.00025097735,0.0000088890865,0.000056039764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000060233637,0.00015907755,0.00014650797,0.000066469045,0.00017096469,0.00012044137,0.00011144748,0.000053760672,0.0000657334],"category_scores_gemma":[0.00006974802,0.0001628644,0.00006911078,0.00020542728,0.000040163177,0.00051793066,0.000020427957,0.00013430661,0.000026076348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021417938,0.000055362278,0.0006514184,0.000009245842,0.000007836058,0.000046140125,0.00017532545,0.00017691763,0.9391565,0.0000612395,0.000015694673,0.059430152],"study_design_scores_gemma":[0.0021259566,0.00057238195,0.41935402,0.00008243066,0.00004694251,0.0005280003,0.000034014112,0.04380647,0.5320187,0.0002170453,0.0007103218,0.0005036935],"about_ca_topic_score_codex":0.000014578362,"about_ca_topic_score_gemma":0.000004068273,"teacher_disagreement_score":0.4187026,"about_ca_system_score_codex":0.00004193485,"about_ca_system_score_gemma":0.00002385411,"threshold_uncertainty_score":0.6641417},"labels":[],"label_agreement":null},{"id":"W2021087861","doi":"10.1523/jneurosci.0091-13.2013","title":"Maternal Immune Activation during Gestation Interacts with<i>Disc1</i>Point Mutation to Exacerbate Schizophrenia-Related Behaviors in Mice","year":2013,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":149,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Centre for Addiction and Mental Health; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Brain and Behavior Research Foundation","keywords":"DISC1; Schizophrenia (object-oriented programming); Prepulse inhibition; Offspring; Immune system; Pregnancy; Biology; Endocrinology; Gene; Immunology; Psychology; Genetics; Psychiatry","score_opus":0.012089000833178053,"score_gpt":0.24712517216761162,"score_spread":0.23503617133443358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021087861","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974931,0.000003830038,0.000365708,0.0013118546,0.0004187686,0.00031449183,0.0000013516866,0.000024607378,0.00006629812],"genre_scores_gemma":[0.9988516,0.000012931355,0.00034532126,0.0006123087,0.000021387163,0.000011030402,3.0761754e-7,0.000019296389,0.00012582485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808085,0.00013357498,0.0006076435,0.00031757375,0.0005494607,0.0003109046],"domain_scores_gemma":[0.9989417,0.00008726829,0.0005490726,0.00013179192,0.000109165565,0.0001810072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019747792,0.00016593214,0.0001811523,0.0005241569,0.00012787236,0.00023570337,0.00039679676,0.000039965755,0.00003556722],"category_scores_gemma":[0.0007393536,0.00013408235,0.000050417973,0.00095859694,0.00010044013,0.0023467743,0.000060015052,0.0003488303,0.00003376619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018283694,0.000079715675,0.0006241374,0.000010225318,5.632708e-7,0.00009137871,0.000708867,0.002978611,0.99396956,0.000022203722,0.000010911027,0.0013209628],"study_design_scores_gemma":[0.00078246056,0.00023139993,0.4380297,0.00013878659,0.0000022446786,0.00035161627,0.00010502875,0.0005382147,0.5596159,0.00009409254,0.0000059139475,0.000104643834],"about_ca_topic_score_codex":0.000080155296,"about_ca_topic_score_gemma":0.000008146394,"teacher_disagreement_score":0.43740556,"about_ca_system_score_codex":0.00012967047,"about_ca_system_score_gemma":0.00009501594,"threshold_uncertainty_score":0.54677194},"labels":[],"label_agreement":null},{"id":"W2021324542","doi":"10.4236/ojpsych.2011.12006","title":"Dopamine receptor D3R and D4R mRNA levels in peripheral lymphocytes in patients with schizophrenia correlate with severity of illness","year":2011,"lang":"en","type":"article","venue":"Open Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Schizophrenia (object-oriented programming); Dopaminergic; Internal medicine; Psychology; Dopamine receptor; Pathophysiology; Dopamine hypothesis of schizophrenia; Receptor; Dopamine receptor D3; Dopamine; Endocrinology; Neuroscience; Medicine; Psychiatry","score_opus":0.017435193816034658,"score_gpt":0.23225152746432476,"score_spread":0.21481633364829011,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021324542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99830925,0.000105884086,0.000016824868,0.000115146075,0.00037639146,0.00024538726,0.000012762264,0.0000031318116,0.00081523467],"genre_scores_gemma":[0.9939485,0.000028130484,0.0057985117,0.0001358096,0.000020639567,0.0000025585077,5.038184e-7,0.000019162273,0.00004617428],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99872357,0.00012696847,0.00044271193,0.00022834947,0.00026757046,0.00021086128],"domain_scores_gemma":[0.99920166,0.000031450374,0.00044738865,0.00015767309,0.000063241314,0.000098590855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022564063,0.00016873228,0.000347084,0.00015978006,0.000054879583,0.00004503155,0.00046696787,0.0000568082,0.00017465682],"category_scores_gemma":[0.00004459665,0.00011690258,0.000029855839,0.000392465,0.000177128,0.0006440938,0.000083272,0.00024830704,0.0000018743808],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007868482,0.0008378302,0.9834662,0.000038814742,0.000016826545,0.000017169605,0.0015940777,0.000021731485,0.00066333136,0.00030831658,0.00008372089,0.005083475],"study_design_scores_gemma":[0.012701997,0.0011212062,0.98228997,0.00040901607,0.000008158032,0.000045854384,0.00063711114,0.000012174202,0.0021443244,0.0003650959,0.000045567434,0.00021954071],"about_ca_topic_score_codex":0.00008385131,"about_ca_topic_score_gemma":0.00059964973,"teacher_disagreement_score":0.005781687,"about_ca_system_score_codex":0.000039402534,"about_ca_system_score_gemma":0.0002755145,"threshold_uncertainty_score":0.47671488},"labels":[],"label_agreement":null},{"id":"W2022559194","doi":"10.3899/jrheum.110903","title":"The Role of Inflammation in the Pathophysiology of Depression: Different Treatments and Their Effects","year":2011,"lang":"en","type":"review","venue":"Journal of Rheumatology Supplement","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"LEO Pharma; Galderma; National Alliance for Research on Schizophrenia and Depression; Amgen Canada; Amgen; Astellas Pharma; Abbott Canada; National Institute of Mental Health; Abbott Laboratories","keywords":"Proinflammatory cytokine; Medicine; Depression (economics); Irritability; Pathophysiology; Inflammation; Neuroscience; Bioinformatics; Immunology; Internal medicine; Anxiety; Psychiatry; Psychology; Biology","score_opus":0.019126681362577717,"score_gpt":0.27813893590840727,"score_spread":0.25901225454582955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022559194","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10658457,0.8924679,0.0000070597057,0.000071699345,0.00021130919,0.00060603954,0.000018349809,0.0000018520395,0.00003118525],"genre_scores_gemma":[0.13925636,0.86066,0.000012189657,0.000010150232,0.0000072174994,0.00003883733,0.0000031688242,0.000009573581,0.0000024903202],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971897,0.0012356495,0.0010593527,0.00016290137,0.0001520031,0.00020039096],"domain_scores_gemma":[0.99581283,0.0021684824,0.0016933137,0.0002640455,0.000029436173,0.00003190351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034653788,0.0002440491,0.0011788951,0.00016145998,0.000070589624,0.00000831182,0.00052639213,0.00013378619,0.000017906634],"category_scores_gemma":[0.00022336814,0.00009548821,0.0002632104,0.00011262008,0.00022051811,0.000045219364,0.00011123461,0.000273651,8.793013e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007859995,0.00022016256,0.0013932445,0.0017951619,0.00011778306,0.0000076143624,0.0013859506,2.7998848e-7,0.00084566424,0.0020721483,0.00010690532,0.9919765],"study_design_scores_gemma":[0.008534164,0.0045445743,0.007434428,0.02260347,0.0010068049,0.0029896353,0.0036016942,0.000039322687,0.04792476,0.05238428,0.84799606,0.0009408049],"about_ca_topic_score_codex":0.00001252571,"about_ca_topic_score_gemma":0.000020810743,"teacher_disagreement_score":0.9910357,"about_ca_system_score_codex":0.000022968297,"about_ca_system_score_gemma":0.000069191374,"threshold_uncertainty_score":0.38938963},"labels":[],"label_agreement":null},{"id":"W2023560341","doi":"10.1016/j.pnpbp.2014.01.013","title":"Inflamed moods: A review of the interactions between inflammation and mood disorders","year":2014,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":610,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Western University","funders":"","keywords":"Mood disorders; Bipolar disorder; Mood; Major depressive disorder; Medicine; Inflammation; Depression (economics); Fluoxetine; Psychiatry; Psychology; Clinical psychology; Bioinformatics; Anxiety; Internal medicine","score_opus":0.04140677399375642,"score_gpt":0.37465264008706844,"score_spread":0.333245866093312,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023560341","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010448343,0.9817723,0.000002759366,0.0035441744,0.0015484145,0.002111654,0.000043248216,0.00006002208,0.00046910727],"genre_scores_gemma":[0.012209024,0.98587275,0.000049692437,0.0011336216,0.00029729214,0.00038864146,0.000011706251,0.000026812835,0.000010460601],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99588084,0.0015935338,0.0010886058,0.00088657497,0.00016387946,0.0003865528],"domain_scores_gemma":[0.99743164,0.0012669998,0.0008336404,0.00033841128,0.000020430101,0.00010890738],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039730108,0.00050105934,0.0013756737,0.00020114027,0.00016350608,0.000024452731,0.000651551,0.0004062867,0.000055062057],"category_scores_gemma":[0.0004990269,0.0002956989,0.0003265725,0.0007274582,0.0011485629,0.00009154135,0.00031737352,0.0011866356,0.0000072565144],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057510257,0.00014889493,0.036238316,0.027885232,0.000042093943,9.586144e-7,0.000019147807,7.2700395e-8,0.0000083246305,0.00064591214,0.00038811172,0.9345654],"study_design_scores_gemma":[0.0018044178,0.00034487448,0.042234298,0.023185218,0.00035215952,0.000058193586,0.000009139233,0.0000073563738,0.000007756818,0.0025525517,0.92880094,0.00064307364],"about_ca_topic_score_codex":7.4926817e-7,"about_ca_topic_score_gemma":0.000009613648,"teacher_disagreement_score":0.93392235,"about_ca_system_score_codex":0.000013639229,"about_ca_system_score_gemma":0.000071387934,"threshold_uncertainty_score":0.9999495},"labels":[],"label_agreement":null},{"id":"W2024344447","doi":"10.1002/hup.1076","title":"Lack of association of GPX1 and MnSOD genes with symptom severity and response to clozapine treatment in schizophrenia subjects","year":2009,"lang":"en","type":"article","venue":"Human Psychopharmacology Clinical and Experimental","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Clozapine; GPX1; Internal medicine; Oxidative stress; Schizophrenia (object-oriented programming); Glutathione peroxidase; Medicine; Antioxidant; Lipid peroxidation; Endocrinology; Psychiatry; Superoxide dismutase; Biology; Biochemistry","score_opus":0.05336549478538501,"score_gpt":0.41203768746196734,"score_spread":0.35867219267658235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024344447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99838424,0.00048576156,4.93268e-7,0.0005654275,0.00008099474,0.00032320444,0.0000118273465,0.000014249117,0.0001337997],"genre_scores_gemma":[0.99833137,0.00034216125,0.000113571674,0.0010088996,0.00003307338,0.000014257696,9.873773e-7,0.000006457152,0.00014924986],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986567,0.00032006012,0.00037055963,0.00038551434,0.00010230523,0.00016484682],"domain_scores_gemma":[0.9993201,0.0003306367,0.00013269414,0.000085583,0.000012874579,0.00011812891],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025854137,0.0001394168,0.0003394249,0.000100764875,0.000072161405,0.000011129954,0.000062681815,0.00009655768,0.000039076887],"category_scores_gemma":[0.000049988976,0.00011447161,0.000033084314,0.00013634418,0.00027134747,0.00006172766,0.000031714542,0.000091851674,0.0000011513113],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0206079,0.0011859633,0.023297118,0.000007718568,0.000019048479,0.000012345319,0.0009530368,0.0000010850559,0.9492799,0.000090033,0.00018740744,0.0043584406],"study_design_scores_gemma":[0.027939446,0.00663465,0.4994596,0.000026660122,0.000020930718,0.000012717583,0.00027237413,0.00003026517,0.4647369,0.00023556112,0.0004209922,0.0002098774],"about_ca_topic_score_codex":0.000015011363,"about_ca_topic_score_gemma":0.000020296662,"teacher_disagreement_score":0.484543,"about_ca_system_score_codex":0.00002788221,"about_ca_system_score_gemma":0.000021974314,"threshold_uncertainty_score":0.46680167},"labels":[],"label_agreement":null},{"id":"W2025026106","doi":"10.1038/npp.2011.154","title":"Astrocytic Hypertrophy in Anterior Cingulate White Matter of Depressed Suicides","year":2011,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":225,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología","keywords":"White matter; Anterior cingulate cortex; Neuroscience; Psychology; Pathology; Anatomy; Medicine; Magnetic resonance imaging; Cognition","score_opus":0.030478915842819993,"score_gpt":0.27712199383394054,"score_spread":0.24664307799112054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025026106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890774,0.000046945413,0.000034190944,0.00014963595,0.0007916523,0.00025828925,0.000006829089,0.000054281696,0.009580764],"genre_scores_gemma":[0.9945137,0.000047373735,0.00017745544,0.004943974,0.00003621899,0.000024076608,3.2785314e-7,0.000037665028,0.00021923536],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9982252,0.0002709723,0.00042391077,0.00051124854,0.00013458081,0.00043406518],"domain_scores_gemma":[0.99937063,0.00010781479,0.00015370814,0.00026027832,0.000021968042,0.0000855712],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006793255,0.00019884552,0.00031441415,0.000303007,0.000037813603,0.000009247798,0.00042791435,0.00007205928,0.0024125618],"category_scores_gemma":[0.00005808768,0.00019024829,0.0000909494,0.00039347773,0.00024160481,0.00012426067,0.000085548105,0.00024109027,0.000250999],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065463904,0.00024739435,0.04575196,0.000028806293,0.0000040253276,0.0001701967,0.00039515318,0.000018832196,0.95161515,0.000022623171,0.000393839,0.0006973811],"study_design_scores_gemma":[0.002581894,0.00023683868,0.6028561,0.000015898997,0.000009589188,0.000055110595,0.00002120507,0.00014568785,0.39350608,0.0001672478,0.00022654698,0.00017780733],"about_ca_topic_score_codex":0.000023391907,"about_ca_topic_score_gemma":0.00000701766,"teacher_disagreement_score":0.55810905,"about_ca_system_score_codex":0.000013201185,"about_ca_system_score_gemma":0.000022973534,"threshold_uncertainty_score":0.9984994},"labels":[],"label_agreement":null},{"id":"W2025725983","doi":"10.1097/yco.0b013e32834b9db6","title":"Inflammatory mechanisms in major depressive disorder","year":2011,"lang":"en","type":"review","venue":"Current Opinion in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":214,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Foothills Medical Centre; University of Calgary; Hotchkiss Brain Institute; Alberta Health Services","funders":"","keywords":"Major depressive disorder; Medicine; Psychiatry; Mood","score_opus":0.06970060117432357,"score_gpt":0.35543661814715666,"score_spread":0.2857360169728331,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025725983","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000016634096,0.9631922,0.00013350818,0.00003866525,0.034357,0.0013788209,0.000059777853,0.00010016406,0.0007232256],"genre_scores_gemma":[0.000019503876,0.9986969,0.00010645418,0.000042850974,0.00037691987,0.00056466373,0.000051055325,0.00010143681,0.000040209867],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962224,0.000500059,0.0011311152,0.0011816855,0.0003078108,0.00065694255],"domain_scores_gemma":[0.9984302,0.00015572684,0.00054376083,0.0007172257,0.0000139825715,0.00013910906],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020101728,0.0006919454,0.0011465175,0.00091935403,0.00008590652,0.000052252966,0.0010532193,0.000447726,0.0002583803],"category_scores_gemma":[0.00016157531,0.0006199338,0.00043784486,0.0009928431,0.00012253401,0.00020932678,0.00026613983,0.0012307611,0.0004433792],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001747957,0.0007053191,0.0003322799,0.024777628,0.0000095548885,0.0000023477544,0.00015310152,0.0000011111691,8.738643e-7,0.061819296,0.003651044,0.90852994],"study_design_scores_gemma":[0.0011107512,0.00003308876,0.00018974226,0.022063242,0.000019819538,0.000013878766,0.00003439194,0.0000052560486,0.0000019720098,0.01354554,0.96223134,0.00075098715],"about_ca_topic_score_codex":0.000009211864,"about_ca_topic_score_gemma":0.000037847924,"teacher_disagreement_score":0.95858026,"about_ca_system_score_codex":0.000091922404,"about_ca_system_score_gemma":0.00049044844,"threshold_uncertainty_score":0.9996252},"labels":[],"label_agreement":null},{"id":"W2025894081","doi":"10.3389/fncel.2013.00068","title":"Interplay between pro-inflammatory cytokines and growth factors in depressive illnesses","year":2013,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Proinflammatory cytokine; Inflammation; Medicine; Neuroscience; Psychology; Immunology","score_opus":0.015955015224959276,"score_gpt":0.2391083446148982,"score_spread":0.22315332938993893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025894081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995236,0.00011977146,0.0022553736,0.00019272794,0.001171633,0.0006055737,0.000008284162,0.00007310879,0.00033753758],"genre_scores_gemma":[0.99911714,0.000085488544,0.00018611326,0.00034468833,0.000030662297,0.000054299475,0.0000012724786,0.000026387732,0.00015394685],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99752116,0.00020330743,0.000371097,0.000925219,0.00036603757,0.00061315915],"domain_scores_gemma":[0.9991964,0.00019591792,0.00012914251,0.00029000058,0.000023547393,0.0001649626],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014716394,0.0002861595,0.00031554658,0.000489679,0.00015134703,0.00018766707,0.00072409183,0.00010304525,0.000015733938],"category_scores_gemma":[0.0011917626,0.00025224301,0.0000473047,0.00087585126,0.00075356907,0.0009414955,0.0002528744,0.00033545398,0.000009069514],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000059625427,0.00003730961,0.6823847,0.00003338764,4.5482955e-7,0.000049875227,0.0004946295,0.000017267934,0.31540444,0.00009637855,0.00040147093,0.0010741187],"study_design_scores_gemma":[0.00045982152,0.000052705338,0.43300167,0.000045285105,0.0000021373796,0.0000044800486,0.00026413522,0.0012299885,0.56196207,0.0021919715,0.00044099547,0.00034475498],"about_ca_topic_score_codex":0.000085165564,"about_ca_topic_score_gemma":0.000011296361,"teacher_disagreement_score":0.24938305,"about_ca_system_score_codex":0.00004594451,"about_ca_system_score_gemma":0.00005172352,"threshold_uncertainty_score":0.99999297},"labels":[],"label_agreement":null},{"id":"W2026429388","doi":"10.1158/0008-5472.can-06-2925","title":"Inhibition of Indoleamine 2,3-Dioxygenase in Dendritic Cells by Stereoisomers of 1-Methyl-Tryptophan Correlates with Antitumor Responses","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":583,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Indoleamine 2,3-dioxygenase; Cancer research; Biology; Chemistry; Immunology; Tryptophan; Biochemistry","score_opus":0.047109739234006236,"score_gpt":0.3536550443331169,"score_spread":0.30654530509911065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026429388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99807274,0.0006528986,0.00004881875,0.000080763035,0.00006556815,0.0004272322,0.00009107346,0.000016318558,0.0005445678],"genre_scores_gemma":[0.9989615,0.00033853995,0.00004893101,0.000067644265,0.000019208253,0.000027187147,0.000003331364,0.000026138288,0.00050752005],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975782,0.00033978277,0.00037675267,0.00039685346,0.000743269,0.0005651185],"domain_scores_gemma":[0.99833465,0.0010206874,0.00010894065,0.00026845853,0.00014789276,0.000119354794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010183146,0.00013653174,0.0002571288,0.00070304016,0.00006644209,0.000018114537,0.0002518442,0.00008210125,0.00012605106],"category_scores_gemma":[0.0004734804,0.000120056546,0.000039789655,0.0016519128,0.0007989618,0.00016601286,0.00007770044,0.00040022712,0.000010595812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014239707,0.00023698343,0.001376435,0.0001707137,0.000004257063,0.0001048322,0.0005232643,0.00002204807,0.9943056,0.00013858992,0.00033931655,0.0013539711],"study_design_scores_gemma":[0.001471484,0.00042452273,0.0038761874,0.0002633507,0.0000011730247,0.000005665511,0.00112603,0.000012406362,0.9924568,0.00009347177,0.00014338017,0.0001255248],"about_ca_topic_score_codex":0.00035259177,"about_ca_topic_score_gemma":0.00032968345,"teacher_disagreement_score":0.0024997524,"about_ca_system_score_codex":0.000099886136,"about_ca_system_score_gemma":0.00021159492,"threshold_uncertainty_score":0.4895764},"labels":[],"label_agreement":null},{"id":"W2028046530","doi":"10.1016/j.jad.2014.03.011","title":"Serotonin 2A receptor clustering in peripheral lymphocytes is altered in major depression and may be a biomarker of therapeutic efficacy","year":2014,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Universidade de Santiago de Compostela","keywords":"Depression (economics); Serotonin transporter; Biomarker; Serotonin; Antidepressant; Internal medicine; Population; Receptor; 5-HT receptor; Case-control study; Medicine; Endocrinology; Psychology; Biology","score_opus":0.018345946597584976,"score_gpt":0.28230255693229506,"score_spread":0.2639566103347101,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028046530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977973,0.00043883553,0.00040150012,0.0005134678,0.00016773533,0.0003469761,0.0000033498773,0.0000078895855,0.00032291593],"genre_scores_gemma":[0.99906546,0.0002453189,0.0001475373,0.00047300255,0.0000189593,0.000008985138,3.2133264e-7,0.000023314313,0.000017101325],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99836576,0.00044959478,0.00039625494,0.00027293016,0.00025072554,0.00026473776],"domain_scores_gemma":[0.99890554,0.0005588481,0.00030284323,0.00013138988,0.000030968666,0.000070425616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039775608,0.00019034972,0.00035758776,0.00036009774,0.000048522274,0.00003317016,0.00020856154,0.00008725234,0.00005891922],"category_scores_gemma":[0.00044552697,0.00015578863,0.00010631906,0.00041504798,0.0001720302,0.0002653879,0.0000662732,0.00020271058,0.0000010439232],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020960667,0.0006798355,0.18835358,0.00012425712,0.00003625511,0.000006152538,0.0060513844,0.00043217064,0.6208888,0.00004533482,0.000121886376,0.18116426],"study_design_scores_gemma":[0.014939848,0.0008238568,0.80199957,0.00046837324,0.000015172197,0.000036023426,0.0015638596,0.0066600726,0.17173569,0.00061555137,0.00076357694,0.00037839965],"about_ca_topic_score_codex":0.00010596362,"about_ca_topic_score_gemma":0.0003326125,"teacher_disagreement_score":0.613646,"about_ca_system_score_codex":0.00008873716,"about_ca_system_score_gemma":0.000049474602,"threshold_uncertainty_score":0.6352876},"labels":[],"label_agreement":null},{"id":"W2030164093","doi":"10.1159/000159775","title":"Cytokine Genes &lt;i&gt;TNF&lt;/i&gt;, &lt;i&gt;IL1A&lt;/i&gt;, &lt;i&gt;IL1B&lt;/i&gt;, &lt;i&gt;IL6&lt;/i&gt;, &lt;i&gt;IL1RN&lt;/i&gt; and &lt;i&gt;IL10&lt;/i&gt;, and Childhood-Onset Mood Disorders","year":2008,"lang":"en","type":"article","venue":"Neuropsychobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Mental Health","keywords":"Cytokine; Chemistry; Endocrinology; Molecular biology; Internal medicine; Biology; Medicine","score_opus":0.014854263867735558,"score_gpt":0.23800200224681645,"score_spread":0.2231477383790809,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030164093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81815404,0.06251961,0.0014579111,0.01146838,0.01954248,0.016474158,0.010205864,0.008080817,0.052096758],"genre_scores_gemma":[0.8536326,0.084297426,0.0027585223,0.013332374,0.0064344285,0.0037519806,0.003832067,0.004867144,0.027093422],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9201854,0.011485364,0.014592979,0.023780009,0.009573546,0.02038274],"domain_scores_gemma":[0.9510534,0.010163812,0.008828255,0.016737428,0.0032717336,0.009945388],"candidate_categories":["metaresearch","metaepi_narrow","metaepi_broad","sts","scholarly_communication","open_science","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","sts","open_science","research_integrity","insufficient_payload"],"category_scores_codex":[0.007220077,0.01702867,0.015413815,0.009775817,0.011342475,0.003305772,0.017150078,0.010049888,0.005044592],"category_scores_gemma":[0.009112473,0.017858354,0.0070814854,0.014729644,0.02084778,0.006784109,0.008505217,0.008844041,0.0065504718],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0046809674,0.008691134,0.0017172905,0.0012277605,0.0021451837,0.0024283614,0.0037933562,0.0009671958,0.78904927,0.028341418,0.13993557,0.017022496],"study_design_scores_gemma":[0.031906314,0.008313196,0.07743373,0.001441731,0.0025298528,0.008612766,0.00019928106,0.0025091306,0.016302628,0.004723323,0.8281722,0.017855853],"about_ca_topic_score_codex":0.0000878742,"about_ca_topic_score_gemma":0.007416066,"teacher_disagreement_score":0.7727466,"about_ca_system_score_codex":0.0025661136,"about_ca_system_score_gemma":0.004512739,"threshold_uncertainty_score":0.9995138},"labels":[],"label_agreement":null},{"id":"W2030396834","doi":"10.1016/j.biopsych.2007.09.024","title":"Inflammatory Cytokine Alterations in Schizophrenia: A Systematic Quantitative Review","year":2007,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":998,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institut universitaire en santé mentale de Montréal","funders":"","keywords":"Cytokine; Schizophrenia (object-oriented programming); Tumor necrosis factor alpha; Immunology; Interleukin; Receptor antagonist; Immune system; Inflammation; In vivo; Interleukin 1 receptor antagonist; Receptor; Psychosis; Interleukin 6; Medicine; Psychology; Internal medicine; Biology; Antagonist; Psychiatry","score_opus":0.1422064003413828,"score_gpt":0.38772997649355684,"score_spread":0.24552357615217404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030396834","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000029859424,0.9938794,0.000055504297,0.00013313383,0.0008785452,0.003252589,0.00007012959,0.0001480917,0.0015527474],"genre_scores_gemma":[0.000022536895,0.99675554,0.00069021434,0.0017627968,0.00015308388,0.00046354238,0.000042494128,0.000037341517,0.0000724569],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.99520284,0.0013543045,0.0017276034,0.0009349507,0.00027855072,0.0005017628],"domain_scores_gemma":[0.9973463,0.0012156251,0.0006894465,0.00058322283,0.000027070117,0.0001383567],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00080630794,0.0006179865,0.0025356873,0.00036877947,0.00011829597,0.00004648895,0.0007503579,0.0005225538,0.00013010154],"category_scores_gemma":[0.0022613737,0.00038400135,0.00070238835,0.0012597908,0.0002224391,0.00009028565,0.00012450348,0.0008385334,0.00086703745],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044471264,0.00046051512,0.000010471257,0.8717985,0.000047192694,0.00007154292,0.000024411373,3.439084e-7,0.000012295331,0.07805157,0.0025223272,0.04695633],"study_design_scores_gemma":[0.00050790625,0.00023155018,0.00003097308,0.55602807,0.00017126478,0.000120146695,0.000031470594,0.0000031688737,0.000001346242,0.0014667839,0.44047242,0.0009349084],"about_ca_topic_score_codex":0.0000018679773,"about_ca_topic_score_gemma":0.000023545013,"teacher_disagreement_score":0.4379501,"about_ca_system_score_codex":0.00008590291,"about_ca_system_score_gemma":0.00028607398,"threshold_uncertainty_score":0.9999109},"labels":[],"label_agreement":null},{"id":"W2030862564","doi":"10.1016/j.bbi.2014.09.012","title":"Astrocytic TNFα regulates the behavioral response to antidepressants","year":2014,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Behavioural despair test; Desipramine; Fluoxetine; Tail suspension test; Tumor necrosis factor alpha; Antidepressant; Astrocyte; Pharmacology; In vivo; Serotonin; Medicine; Hippocampus; Internal medicine; Endocrinology; Psychology; Biology; Central nervous system; Receptor","score_opus":0.03376739156277703,"score_gpt":0.29923627278621984,"score_spread":0.2654688812234428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030862564","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99766064,0.00002786772,0.00004349157,0.001287263,0.00015620551,0.0004122081,0.000019685749,0.00010519387,0.00028743222],"genre_scores_gemma":[0.9971866,0.000005731027,0.00008142192,0.0016463578,0.000027619932,0.000055447003,0.0000025859288,0.000024837645,0.00096938165],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99789923,0.00089309353,0.00021522728,0.00035488931,0.00024527794,0.00039226748],"domain_scores_gemma":[0.9982866,0.00079392263,0.000059592916,0.00067907275,0.000027240643,0.00015357368],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070785393,0.00020319904,0.0001846554,0.00009909749,0.00061868166,0.00015391957,0.00051681686,0.000076050455,0.00008263024],"category_scores_gemma":[0.0010961717,0.00015024246,0.000071081995,0.00028738377,0.00032813882,0.00016395,0.00027031414,0.00028719578,0.0000578418],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003567613,0.00022069746,0.004625689,0.000004144235,0.0000012301015,0.0000072478206,0.00083047367,0.0000026136381,0.9690427,0.00019808538,0.0011283534,0.023581997],"study_design_scores_gemma":[0.00075212144,0.00036552927,0.77893454,0.00001797174,0.000017026787,0.000045186247,0.0003575384,0.000026078467,0.21271656,0.00012062796,0.0064073103,0.0002395127],"about_ca_topic_score_codex":0.00012653029,"about_ca_topic_score_gemma":0.000024431125,"teacher_disagreement_score":0.77430886,"about_ca_system_score_codex":0.000019614848,"about_ca_system_score_gemma":0.000026713042,"threshold_uncertainty_score":0.61267096},"labels":[],"label_agreement":null},{"id":"W2030922811","doi":"10.1038/sj.jcbfm.9591524.0615","title":"Adenovirus-induced overexpression of D<sub>2</sub> receptors alters the responsivity of striatal dopamine","year":2005,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dopamine; Neuroscience; Responsivity; Receptor; Dopamine receptor; Biology; Chemistry; Physics; Medicine; Internal medicine; Optics","score_opus":0.018561471461428426,"score_gpt":0.24763213603775516,"score_spread":0.22907066457632674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030922811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99711806,0.0006513438,0.00004114452,0.0008613172,0.00087441405,0.00022759565,0.00005182349,0.000016210752,0.00015808891],"genre_scores_gemma":[0.9978599,0.00030631057,0.0006827359,0.00037573947,0.0006994571,0.0000021887176,0.0000010596356,0.000033641616,0.000038972626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963271,0.0006871462,0.0011681201,0.00029885853,0.0011139039,0.00040486272],"domain_scores_gemma":[0.9971046,0.0005959193,0.0014443776,0.0004649915,0.00019515671,0.00019496545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094955973,0.0002966512,0.00072480174,0.00033590072,0.00012889132,0.000039599367,0.00084024854,0.0001464208,0.0001218654],"category_scores_gemma":[0.001850446,0.00019474796,0.00049183686,0.0006250363,0.00023949344,0.0007157294,0.00016210474,0.000637958,0.000009918809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073731854,0.0004342658,0.00007726151,0.000021241809,0.000057232148,0.000005201504,0.00054156827,0.00016710708,0.9748258,0.00026512519,0.0008484947,0.022019386],"study_design_scores_gemma":[0.0033462783,0.0002716599,0.0057075494,0.00011862476,0.00012465891,0.00007328198,0.00017091737,0.000082614715,0.9876542,0.00020936053,0.0020508277,0.0001900223],"about_ca_topic_score_codex":0.000009180943,"about_ca_topic_score_gemma":0.000008828759,"teacher_disagreement_score":0.021829365,"about_ca_system_score_codex":0.000021869437,"about_ca_system_score_gemma":0.00021352859,"threshold_uncertainty_score":0.7941591},"labels":[],"label_agreement":null},{"id":"W2031329056","doi":"10.4088/jcp.08r04505","title":"Inflammation and the Phenomenology, Pathophysiology, Comorbidity, and Treatment of Bipolar Disorder","year":2009,"lang":"en","type":"review","venue":"The Journal of Clinical Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":505,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Bipolar disorder; Comorbidity; Pathophysiology; Phenomenology (philosophy); Inflammation; Medicine; Psychotherapist; Psychology; Psychiatry; Internal medicine; Philosophy; Cognition; Epistemology","score_opus":0.09468775670641474,"score_gpt":0.4002596789173289,"score_spread":0.3055719222109141,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031329056","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014855492,0.9807997,0.000011178991,0.0028938921,0.00084934244,0.00046494094,0.000012791547,0.000006132953,0.00010654545],"genre_scores_gemma":[0.0009135447,0.9979997,0.00007813071,0.00030253388,0.00065126066,0.000002878936,0.0000010482423,0.00001587479,0.00003500817],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9953436,0.002366978,0.0017386217,0.00019975637,0.00018265085,0.00016838136],"domain_scores_gemma":[0.99351776,0.0037196171,0.002297797,0.0003533317,0.000034648587,0.000076865384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014550497,0.00027066687,0.0017828755,0.00009082874,0.00013543421,0.000019144449,0.00045461612,0.00025588166,0.00001159221],"category_scores_gemma":[0.00064226054,0.00011091855,0.0005369827,0.00017200381,0.0014842064,0.00006500975,0.00007716633,0.00059749134,0.00000435823],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026515097,0.00022663138,0.000050245322,0.00029034997,0.000081012455,0.0000011720787,0.0000920774,8.7112613e-7,0.000003973745,0.0016693273,0.0001560973,0.9971631],"study_design_scores_gemma":[0.004527893,0.002274537,0.0011046657,0.0010518674,0.0010467418,0.00017623357,0.00011008786,0.000011308327,0.0000019851486,0.033706423,0.9557809,0.00020736344],"about_ca_topic_score_codex":0.0000063845964,"about_ca_topic_score_gemma":0.000013046234,"teacher_disagreement_score":0.99695575,"about_ca_system_score_codex":0.00000987189,"about_ca_system_score_gemma":0.00019553374,"threshold_uncertainty_score":0.54686207},"labels":[],"label_agreement":null},{"id":"W2031946701","doi":"10.1016/j.bbi.2012.07.023","title":"Central administration of murine interferon-α induces depressive-like behavioral, brain cytokine and neurochemical alterations in mice: A mini-review and original experiments","year":2012,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Neurochemical; Cytokine; Neuroscience; Psychology; Sickness behavior; Proinflammatory cytokine; Tumor necrosis factor alpha; Immunology; Medicine; Inflammation","score_opus":0.0520406086677173,"score_gpt":0.34859170704141007,"score_spread":0.29655109837369276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031946701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964479,0.002408129,0.0000069890043,0.00048545998,0.0000830083,0.00045903094,0.000051611314,0.00001854505,0.00003928422],"genre_scores_gemma":[0.99848384,0.0006023283,0.00009256953,0.00063833315,0.000019005238,0.000072289986,0.00002949716,0.00001354925,0.00004861071],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987213,0.00022325503,0.0003406128,0.0002731038,0.00013333764,0.00030839056],"domain_scores_gemma":[0.9993774,0.00015213767,0.00011213976,0.00017663409,0.000018601906,0.00016302928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013801479,0.00020025519,0.00026867553,0.00008972769,0.00012046457,0.000046697092,0.00013237618,0.000078244506,0.00005762745],"category_scores_gemma":[0.0001507401,0.00019267634,0.000031613137,0.00015797168,0.00029141226,0.000444519,0.00013714694,0.00024927224,6.452834e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082639854,0.0009589322,0.017073551,0.00011278263,0.0000021180851,0.000006606529,0.0010390516,2.5525399e-8,0.9780736,0.00006280913,0.00024191567,0.0023459885],"study_design_scores_gemma":[0.0016069451,0.0005157137,0.3783753,0.00022794577,0.00006859091,0.00021253667,0.00045277085,0.0000061241867,0.61738765,0.000011073919,0.00080449966,0.00033086134],"about_ca_topic_score_codex":0.000111088906,"about_ca_topic_score_gemma":0.000027570357,"teacher_disagreement_score":0.36130175,"about_ca_system_score_codex":0.000016320195,"about_ca_system_score_gemma":0.00003209691,"threshold_uncertainty_score":0.7857113},"labels":[],"label_agreement":null},{"id":"W2031959289","doi":"10.1007/s12035-015-9183-5","title":"Toward Omics-Based, Systems Biomedicine, and Path and Drug Discovery Methodologies for Depression-Inflammation Research","year":2015,"lang":"en","type":"review","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Health and Medical Research Council","keywords":"Biomedicine; Immune system; Inflammation; Computational biology; Drug discovery; Systems biology; Proteomics; KEGG; Metabolomics; Biology; Bioinformatics; Transcriptome; Immunology; Gene expression; Genetics","score_opus":0.2419086449073754,"score_gpt":0.4297580763795448,"score_spread":0.18784943147216937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031959289","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014989898,0.9886901,0.0060136286,0.0002656407,0.0007090413,0.0024461958,0.00020247302,0.00008650667,0.00008743161],"genre_scores_gemma":[0.0017934092,0.99644476,0.00059030537,0.00018647403,0.00012408162,0.00050926354,0.00014128012,0.00008264303,0.00012775909],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9943422,0.0033147817,0.0005037759,0.0011068159,0.00020835601,0.0005240858],"domain_scores_gemma":[0.99528944,0.0037681584,0.00026798717,0.00045947655,0.00008465571,0.00013026754],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016074283,0.00040419464,0.0012181372,0.0004966069,0.000151126,0.00014733554,0.0004331547,0.00037429132,9.073936e-7],"category_scores_gemma":[0.0035018618,0.00028891704,0.00014783429,0.00035254456,0.00072900514,0.00009432556,0.00035411617,0.00046417926,0.000005262946],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022740393,0.00007464838,0.0000071395984,0.03472097,0.000071797185,0.00029803385,0.00021578619,0.000032488246,0.07516457,0.0048674066,0.0046612774,0.87965846],"study_design_scores_gemma":[0.0008954996,0.00035626633,0.0000025028803,0.0015927716,0.000116772164,0.000202447,0.00008160471,0.00013522284,0.00517974,0.0012849261,0.9896694,0.00048286316],"about_ca_topic_score_codex":0.00001828351,"about_ca_topic_score_gemma":0.0000010531023,"teacher_disagreement_score":0.9850081,"about_ca_system_score_codex":0.000042897656,"about_ca_system_score_gemma":0.00024924544,"threshold_uncertainty_score":0.9999563},"labels":[],"label_agreement":null},{"id":"W2033253360","doi":"10.1016/j.ajpath.2010.10.028","title":"Serotonin Activates Dendritic Cell Function in the Context of Gut Inflammation","year":2011,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada; Crohn's and Colitis Foundation; McMaster University","keywords":"Inflammation; Serotonin; Context (archaeology); Dendritic cell; Biology; Function (biology); Immunology; Neuroscience; Medicine; Pathology; Cell biology; Immune system; Receptor; Biochemistry","score_opus":0.02409367218764087,"score_gpt":0.24513298147152895,"score_spread":0.2210393092838881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033253360","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979526,0.000024466262,0.0003280565,0.00019398412,0.00010477592,0.000077101446,0.000001000841,0.000003589899,0.0013144226],"genre_scores_gemma":[0.9991398,0.000033613167,0.000181514,0.0006010141,0.000026428213,0.0000032190078,1.4793045e-7,0.000005495658,0.0000087735025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894786,0.00042676768,0.00029350136,0.00008656716,0.00011981353,0.00012549094],"domain_scores_gemma":[0.9991319,0.00023803541,0.00046514516,0.00010223057,0.000040011,0.000022660908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002678961,0.000065248416,0.00017272717,0.00014355833,0.000024499866,0.000004872358,0.00021372749,0.000024255907,0.00004274527],"category_scores_gemma":[0.00021363949,0.00004489893,0.000053520926,0.0002448263,0.00033890293,0.00012645122,0.000013707565,0.00017780601,0.000008026917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020689392,0.000109902234,0.00438184,0.000006521493,0.0000022089998,0.00012320872,0.0073562637,0.000005607423,0.9585678,0.0009938239,0.000030642568,0.028215269],"study_design_scores_gemma":[0.0009727819,0.0025105728,0.12913938,0.000023208228,0.00001398994,0.0006756507,0.02003344,0.00001904966,0.843891,0.0023338783,0.00028071378,0.00010629903],"about_ca_topic_score_codex":0.000017327633,"about_ca_topic_score_gemma":0.000009738468,"teacher_disagreement_score":0.124757536,"about_ca_system_score_codex":0.000010908016,"about_ca_system_score_gemma":0.000031828076,"threshold_uncertainty_score":0.18309252},"labels":[],"label_agreement":null},{"id":"W2034013647","doi":"10.1074/jbc.m111.262139","title":"NADH Oxidase Activity of Indoleamine 2,3-Dioxygenase","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Catalase; Superoxide dismutase; Adduct; Hydrogen peroxide; Superoxide; Enzyme; Heme; Ferrous; Peroxide; Photochemistry; Biochemistry; Stereochemistry; Organic chemistry","score_opus":0.07573280685252408,"score_gpt":0.2647037355387455,"score_spread":0.1889709286862214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034013647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99509746,0.00006996222,0.000053136097,0.000035507426,0.0000469859,0.000029581031,0.0000091151705,0.000011104501,0.0046471455],"genre_scores_gemma":[0.99943566,0.000061806764,0.00019203823,0.00012008631,0.00007289421,6.348485e-7,2.4808006e-7,0.000004531441,0.00011210554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918115,0.000053328335,0.00029230345,0.00014597869,0.00016176845,0.00016546536],"domain_scores_gemma":[0.9991651,0.00013827701,0.00038606243,0.00013307828,0.000050964263,0.00012649836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016207411,0.000108840904,0.00024192095,0.000023487595,0.000027479462,0.0000054251,0.00032191956,0.00013023967,0.00060388236],"category_scores_gemma":[0.0010739727,0.00007032399,0.00016208338,0.0001346013,0.0002240981,0.00007280465,0.000059991875,0.00027086784,0.0000054264096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002769685,0.00037747374,0.00021018201,0.00002154017,0.0000056792906,0.00007571176,0.00003773816,4.1903434e-7,0.9969849,0.000015710995,0.000076645214,0.0019170535],"study_design_scores_gemma":[0.000488257,0.00019375909,0.0075550964,0.000017262177,0.000001755137,0.00012289967,0.000042268508,0.0000032443515,0.99084914,0.00047674176,0.00016582602,0.00008376056],"about_ca_topic_score_codex":0.0000017172405,"about_ca_topic_score_gemma":1.0902251e-7,"teacher_disagreement_score":0.0073449146,"about_ca_system_score_codex":0.000015542957,"about_ca_system_score_gemma":0.000037745584,"threshold_uncertainty_score":0.66120887},"labels":[],"label_agreement":null},{"id":"W2034269266","doi":"10.1016/s0893-133x(99)00086-x","title":"Effects on Mood of Acute Phenylalanine/Tyrosine Depletion in Healthy Women","year":2000,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":119,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Medical Research Council; National Alliance for Research on Schizophrenia and Depression","keywords":"Phenylalanine; Tyrosine; Mood; Psychology; Medicine; Internal medicine; Endocrinology; Clinical psychology; Psychiatry; Chemistry; Biochemistry; Amino acid","score_opus":0.011248391338276941,"score_gpt":0.2910390762269513,"score_spread":0.27979068488867437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034269266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906572,0.000018839528,0.0000035828443,0.0013976118,0.0005852254,0.00046428747,0.000013817792,0.00008912828,0.0067702974],"genre_scores_gemma":[0.98549175,0.00038097365,0.00001695254,0.013562759,0.00009019088,0.00009302855,0.0000015814072,0.000032570028,0.00033017955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980032,0.00044428365,0.00031360073,0.00053341204,0.00019613201,0.00050937245],"domain_scores_gemma":[0.99925494,0.0003309903,0.00009003832,0.00018620324,0.000011050084,0.00012678749],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000096380645,0.00019523555,0.0002788956,0.0002046948,0.000055663117,0.00000819574,0.00029866755,0.000084402054,0.0011059063],"category_scores_gemma":[0.000046041594,0.0001906356,0.0000550419,0.00060972164,0.0001137498,0.00007467951,0.000022482289,0.00030454827,0.0002527607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044303266,0.00062511687,0.00029197775,0.000036091482,0.0000066029543,0.00010357485,0.00033999077,0.00008064062,0.9795806,0.00009909308,0.0010838931,0.013322089],"study_design_scores_gemma":[0.0203733,0.0061748615,0.18498074,0.00002898815,0.000022004966,0.00007516929,0.0000210503,0.00041182886,0.7781287,0.0005633154,0.008754761,0.00046528166],"about_ca_topic_score_codex":0.0000068030304,"about_ca_topic_score_gemma":0.000002516219,"teacher_disagreement_score":0.2014519,"about_ca_system_score_codex":0.000055069155,"about_ca_system_score_gemma":0.000028641927,"threshold_uncertainty_score":0.99980724},"labels":[],"label_agreement":null},{"id":"W2034445092","doi":"10.1002/ibd.21849","title":"Serum Analysis of Tryptophan Catabolism Pathway: Correlation With Crohnʼs Disease Activity","year":2011,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":156,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institutes of Health; Crohn's and Colitis Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; Crohn's and Colitis Foundation of America; Howard Hughes Medical Institute","keywords":"Catabolism; Crohn's disease; Tryptophan; Medicine; Disease; Correlation; Internal medicine; Immunology; Gastroenterology; Chemistry; Biochemistry; Metabolism; Amino acid","score_opus":0.01982572585084748,"score_gpt":0.22617378143187017,"score_spread":0.20634805558102268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034445092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969372,0.00011300453,0.00041514516,0.000027517452,0.00012496303,0.00032690642,0.00079764525,0.00018877412,0.0010688019],"genre_scores_gemma":[0.9994832,0.000024860072,0.000025128282,0.0001779731,0.00003592804,0.000050455423,0.000025833122,0.00003129139,0.00014529948],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981729,0.00017890854,0.0002887257,0.00054775237,0.0004675801,0.0003441809],"domain_scores_gemma":[0.9984703,0.00013112547,0.00028993862,0.0006355743,0.0000680627,0.00040499383],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059130318,0.0002733529,0.00032135664,0.0004037495,0.00016162224,0.000036059893,0.00033149633,0.00006385973,0.00052003836],"category_scores_gemma":[0.00023777467,0.00023465518,0.0002543727,0.0008430357,0.00030638967,0.0005734987,0.00007642777,0.00011409588,0.000036791884],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033019122,0.0012834012,0.9713185,0.00021061981,0.00032561802,0.00043754047,0.0015023549,0.0012686037,0.009331936,0.0070870034,0.00016262755,0.0037699263],"study_design_scores_gemma":[0.0006637174,0.000048845515,0.98533165,0.00002751647,0.00041115138,8.5775616e-7,0.00007988684,0.002225001,0.010334502,0.00042786938,0.00014611121,0.00030291456],"about_ca_topic_score_codex":0.00003722951,"about_ca_topic_score_gemma":0.00006391903,"teacher_disagreement_score":0.01401317,"about_ca_system_score_codex":0.000029527137,"about_ca_system_score_gemma":0.00022006122,"threshold_uncertainty_score":0.95689607},"labels":[],"label_agreement":null},{"id":"W2035229071","doi":"10.1016/s0165-1781(14)70004-6","title":"Understanding the role of adjunctive nonpharmacological therapies in management of the multiple pathways to depression","year":2014,"lang":"en","type":"review","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"START Clinic; Western University; Lakehead University; Windsor Regional Hospital; McGill University; McGill University Health Centre","funders":"National Institute of Mental Health; National Institutes of Health; Valeant Pharmaceuticals International","keywords":"Major depressive disorder; Pharmacotherapy; Psychology; Medicine; Neuroscience; Neuroplasticity; Adjunctive treatment; Psychiatry; Clinical psychology; Cognition; Internal medicine","score_opus":0.28382743780137787,"score_gpt":0.4216165583339735,"score_spread":0.13778912053259562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035229071","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0027165767,0.98485774,0.00010552324,0.00040033623,0.0005988573,0.0035418326,0.000046147306,0.000020562467,0.0077124154],"genre_scores_gemma":[0.19910516,0.8003334,0.00006933476,0.00006673329,0.00005284127,0.00027275702,0.0000012057054,0.00003057246,0.00006800119],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99585176,0.0018718145,0.00045032374,0.0005084522,0.0008781615,0.00043946726],"domain_scores_gemma":[0.997722,0.0013964653,0.00018939363,0.0006001107,0.000032870474,0.000059130736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013771754,0.00021498043,0.0005539505,0.00026310747,0.00023209648,0.000027292514,0.0015587177,0.00013916212,0.00006299386],"category_scores_gemma":[0.0002086356,0.00010176075,0.00028229493,0.0014994331,0.0003849073,0.000032792217,0.00071671564,0.0007882069,0.000019692592],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052445155,0.0016800492,0.005357301,0.02475906,0.00023165192,0.000007659633,0.0026944147,0.00008808857,0.0024990835,0.06430922,0.003287208,0.8945618],"study_design_scores_gemma":[0.0030447894,0.00073069474,0.006207696,0.03662567,0.00019402754,0.000012155921,0.016807811,0.00038316086,0.0015208622,0.06470254,0.86871254,0.0010580621],"about_ca_topic_score_codex":0.000015006167,"about_ca_topic_score_gemma":0.00003149885,"teacher_disagreement_score":0.8935037,"about_ca_system_score_codex":0.000105302504,"about_ca_system_score_gemma":0.0001310104,"threshold_uncertainty_score":0.41496828},"labels":[],"label_agreement":null},{"id":"W2037080364","doi":"10.1016/s0924-9338(13)77113-x","title":"2249 – Efficacy And Safety Of 3 Agomelatine Dose Regimens (10, 25, 25-50 Mg) Versus Placebo In Out-patients Suffering From Moderate To Severe Major Depressive Disorder","year":2013,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Agomelatine; Placebo; Discontinuation; Internal medicine; Medicine; Major depressive disorder; Adverse effect; Gastroenterology; Randomized controlled trial; Antidepressant","score_opus":0.015281796797628073,"score_gpt":0.24257343648722893,"score_spread":0.22729163968960087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037080364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98027915,0.00019588115,0.0001296092,0.00058353925,0.00094841333,0.00084142666,0.000074715215,0.0000786423,0.016868647],"genre_scores_gemma":[0.9973394,0.000019087145,0.0009494786,0.00047899285,0.000089853886,0.000013941,0.000018909526,0.00007713391,0.0010131684],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9977336,0.00034710727,0.00047400084,0.0007445407,0.00027765863,0.00042310753],"domain_scores_gemma":[0.99880826,0.00025725554,0.00019290742,0.00050542614,0.000036597292,0.00019956715],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010130309,0.00031819165,0.00030419976,0.00016245988,0.00014434154,0.000075762306,0.00040033547,0.00006003784,0.00036001974],"category_scores_gemma":[0.00031353132,0.00030070392,0.00006427143,0.00025160558,0.000098845296,0.00026916034,0.00031532164,0.000257066,0.0005326135],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0739381,0.010475949,0.4527485,0.0009583576,0.0006239421,0.00016498826,0.06808749,0.010122502,0.24017663,0.0056051333,0.070295006,0.06680338],"study_design_scores_gemma":[0.052998994,0.00072272366,0.9374672,0.00050498324,0.000038766444,0.0000024374733,0.0009709914,0.0007607508,0.0014256029,0.0006817539,0.0032579796,0.0011678116],"about_ca_topic_score_codex":0.000100458994,"about_ca_topic_score_gemma":0.00015364666,"teacher_disagreement_score":0.4847187,"about_ca_system_score_codex":0.000025250069,"about_ca_system_score_gemma":0.00002994356,"threshold_uncertainty_score":0.9999445},"labels":[],"label_agreement":null},{"id":"W2037158815","doi":"10.1016/j.biopsych.2012.02.034","title":"Clustering of Depression and Inflammation in Adolescents Previously Exposed to Childhood Adversity","year":2012,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":335,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; Canadian Institutes of Health Research","keywords":"Depression (economics); Inflammation; Psychopathology; Psychology; Clinical psychology; Medicine; Psychiatry; Internal medicine","score_opus":0.02718386765810498,"score_gpt":0.2568042815499199,"score_spread":0.22962041389181492,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037158815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99867487,0.00023513444,0.00020040156,0.000096769385,0.0002469605,0.00025545212,0.0000018639058,0.000028328683,0.00026024863],"genre_scores_gemma":[0.9989576,0.000035575657,0.00058208784,0.00035155643,0.00006250132,0.0000040956247,7.186861e-7,0.0000033240867,0.0000025413058],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992984,0.00008353073,0.00015357787,0.0001914286,0.0000734697,0.00019961914],"domain_scores_gemma":[0.9997339,0.000020877209,0.00005370851,0.000098249446,0.000004118101,0.00008910425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105239,0.00007912706,0.000104730425,0.000055568882,0.00003701102,0.000005069424,0.00010833101,0.00007909935,0.0000099550525],"category_scores_gemma":[0.00017025901,0.000059653743,0.000026113335,0.00013326055,0.000035052817,0.000093409864,0.000114200295,0.00007643209,0.000009915186],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008559528,0.00019593828,0.8948865,0.00003049445,5.8828033e-7,1.8526745e-7,0.00029618485,0.000008875683,0.09721558,0.00006774288,0.000026022177,0.0071862848],"study_design_scores_gemma":[0.0005170279,0.00007382812,0.9879455,0.00010140726,8.906851e-7,0.0000019131871,0.00008280492,0.00002072435,0.010992926,0.00012887445,0.000051734594,0.000082353006],"about_ca_topic_score_codex":0.0000029653079,"about_ca_topic_score_gemma":0.000010459625,"teacher_disagreement_score":0.09305901,"about_ca_system_score_codex":0.000008582274,"about_ca_system_score_gemma":0.0000067974825,"threshold_uncertainty_score":0.2432609},"labels":[],"label_agreement":null},{"id":"W2037163638","doi":"10.2147/ndt.s65740","title":"Kynurenine and depressive symptoms in a poststroke population","year":2014,"lang":"en","type":"article","venue":"Neuropsychiatric Disease and Treatment","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Rehabilitation Institute; Sunnybrook Hospital; Sunnybrook Health Science Centre; Heart and Stroke Foundation","funders":"Toronto Rehabilitation Institute; Heart and Stroke Foundation of Canada","keywords":"Medicine; Kynurenine; Depression (economics); Stroke (engine); Population; Internal medicine; Proinflammatory cytokine; Cohort; Psychiatry; Inflammation; Tryptophan; Environmental health","score_opus":0.0078697131990553,"score_gpt":0.2298705031962311,"score_spread":0.2220007899971758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037163638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99809825,0.0004892818,0.000007711989,0.00044721478,0.00010211407,0.00026042448,0.000016080261,0.000045911853,0.00053297996],"genre_scores_gemma":[0.9989719,0.0003246337,0.000016971342,0.00046039387,0.00005388092,0.000030684685,0.0000073249994,0.000013643723,0.00012059275],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990689,0.00009746009,0.0001263306,0.00042008178,0.00010754541,0.00017968139],"domain_scores_gemma":[0.9995286,0.000082578605,0.000044799835,0.00015480605,0.000004342142,0.00018488329],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000015466117,0.00015436059,0.00012442158,0.00012739451,0.00008496865,0.000044858556,0.000046284025,0.000022650733,0.000009455504],"category_scores_gemma":[0.00005857658,0.00012166903,0.000034735032,0.00017113445,0.000036872316,0.0000871521,0.000024577554,0.000040266914,0.000006071935],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033793846,0.00073816074,0.848581,0.000025231066,0.000011614698,0.00007417743,0.00014265205,0.000047433536,0.0015873841,0.005468389,0.000045822882,0.1429402],"study_design_scores_gemma":[0.0023688036,0.00030220358,0.99474084,0.000008471939,0.00003596794,0.000007899644,0.000004745907,0.00080300396,0.00014592572,0.0011542311,0.00030142925,0.00012649776],"about_ca_topic_score_codex":0.00006820995,"about_ca_topic_score_gemma":0.00003242965,"teacher_disagreement_score":0.14615981,"about_ca_system_score_codex":0.000013910943,"about_ca_system_score_gemma":0.000011288299,"threshold_uncertainty_score":0.49615192},"labels":[],"label_agreement":null},{"id":"W2038609004","doi":"10.1186/1471-2334-14-s2-o16","title":"Liver fibrosis is strongly associated with an enhanced level of immunosuppressive tryptophan catabolism independently of HCV viremia in ART-treated HIV/HCV co-infected patients","year":2014,"lang":"en","type":"article","venue":"BMC Infectious Diseases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Viremia; Medical microbiology; Virology; Medicine; Immunology; Human immunodeficiency virus (HIV); Hepatitis C; Hepacivirus; Parasitology; Viral disease; Pathology","score_opus":0.019009321214030005,"score_gpt":0.2493679737738463,"score_spread":0.2303586525598163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038609004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957286,0.0000309407,0.0002566371,0.0000025637405,0.00008722508,0.00064905465,0.0015963314,0.0001443501,0.0015042962],"genre_scores_gemma":[0.9992885,0.000018279236,0.00001907858,0.00008627801,0.000022902992,0.000065279535,0.00031148043,0.000056109646,0.00013211346],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971395,0.0005473946,0.0005570818,0.00065780315,0.000602029,0.0004962051],"domain_scores_gemma":[0.99790466,0.0004996078,0.000631095,0.0005224794,0.0002551646,0.00018697791],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007743962,0.00040111397,0.0005900397,0.0003464172,0.00013345649,0.000050458606,0.00035245952,0.0001847022,0.00024662534],"category_scores_gemma":[0.0011857603,0.0003678901,0.00015507085,0.00069746154,0.00034104876,0.00050386816,0.00007958275,0.0002017292,0.000032202883],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008347705,0.003304448,0.949546,0.0001244493,0.00005236017,0.000004305562,0.0008143238,0.00034896287,0.04317867,0.000101573074,0.0003117432,0.0013784083],"study_design_scores_gemma":[0.0058356915,0.0007413003,0.7791164,0.00016215524,0.00005703649,6.0357814e-7,0.000047750003,0.00030717647,0.2132912,0.00006811314,0.00002224034,0.00035035214],"about_ca_topic_score_codex":0.00042568037,"about_ca_topic_score_gemma":0.0007377662,"teacher_disagreement_score":0.1704296,"about_ca_system_score_codex":0.00010868029,"about_ca_system_score_gemma":0.00017178136,"threshold_uncertainty_score":0.99987733},"labels":[],"label_agreement":null},{"id":"W2038829654","doi":"10.2174/138161212803523635","title":"The Canadian Biomarker Integration Network in Depression (CAN-BIND): Advances in Response Prediction","year":2012,"lang":"en","type":"article","venue":"Current Pharmaceutical Design","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto","funders":"H. Lundbeck A/S; Wellcome Trust","keywords":"Personalized medicine; Neuroimaging; Biomarker; Precision medicine; Major depressive disorder; Depression (economics); Medicine; Biomarker discovery; Informatics; Modalities; Bioinformatics; Mood; Proteomics; Psychiatry; Pathology; Biology","score_opus":0.11580892221327473,"score_gpt":0.3749051576990403,"score_spread":0.2590962354857656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038829654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86514974,0.07245578,0.027815511,0.006185802,0.017226165,0.00604013,0.0000914845,0.00041903145,0.004616362],"genre_scores_gemma":[0.9978732,0.0015428821,0.00004557304,0.0003006358,0.000106682564,0.00009549732,0.000003584025,0.000012634874,0.000019342579],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.997221,0.001284894,0.00027083966,0.0002691487,0.0002442489,0.00070986414],"domain_scores_gemma":[0.9983436,0.0011603171,0.000046059424,0.00014921965,0.000014518465,0.00028631053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014649718,0.00014734585,0.000098811295,0.00015901744,0.00027636485,0.00006885186,0.00021862719,0.00007705403,0.000037413167],"category_scores_gemma":[0.001107836,0.00010584015,0.00003403843,0.00066127174,0.00015518001,0.00042335156,0.00003056314,0.00041000688,0.000034465178],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027634832,0.00031209056,0.0497947,0.00001851466,0.0000023235548,0.000010475601,0.00054610556,0.00092737214,0.04199433,0.0025063483,0.003308761,0.89781547],"study_design_scores_gemma":[0.0030425203,0.00010901983,0.4244347,0.00034358914,0.000014587577,0.000017717806,0.00014080602,0.0945559,0.07959098,0.0033760492,0.39378166,0.0005924481],"about_ca_topic_score_codex":0.00012338448,"about_ca_topic_score_gemma":0.004216808,"teacher_disagreement_score":0.89722306,"about_ca_system_score_codex":0.00025724285,"about_ca_system_score_gemma":0.00014232832,"threshold_uncertainty_score":0.43160358},"labels":[],"label_agreement":null},{"id":"W2039829650","doi":"10.1139/y07-124","title":"Alteration of superoxide- and nitric oxide-mediated antimicrobial function of macrophages by in vivo cocaine exposure","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Nitric oxide; Superoxide; Respiratory burst; Reactive oxygen species; In vivo; Chemistry; Proinflammatory cytokine; Pharmacology; Nitric oxide synthase; Reactive nitrogen species; Microbiology; Immunology; Biochemistry; Inflammation; Biology; Enzyme","score_opus":0.012253261985940423,"score_gpt":0.22723541156108915,"score_spread":0.21498214957514872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039829650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987747,0.0006288834,0.000011963544,0.00018404929,0.000254546,0.00007912889,0.00004696905,0.0000017857554,0.00001796494],"genre_scores_gemma":[0.9983847,0.0006513661,0.000012593713,0.0008753623,0.000041232375,0.0000010458772,0.000002984069,0.00000563673,0.000025075366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991186,0.00021695725,0.00031793187,0.00012901789,0.00003996111,0.00017750151],"domain_scores_gemma":[0.9993867,0.00019536754,0.00019340495,0.000036237136,0.00005541487,0.00013284298],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000101049576,0.000090188114,0.00026467573,0.00028206245,0.000069910115,0.0000020310401,0.00008168467,0.000096937765,0.00024264722],"category_scores_gemma":[0.00007390623,0.00008434893,0.000029710927,0.00019275125,0.0005089948,0.00011142275,0.000008909349,0.00017834046,5.6002165e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002051002,0.00003995378,0.0050227535,0.000039707353,0.00001270788,0.00003992169,0.0001992172,0.000043001837,0.98973435,0.000022293149,0.004556137,0.000084841515],"study_design_scores_gemma":[0.0017138204,0.00031548244,0.05793303,0.000009044208,0.000012750016,0.00013671866,0.000029269964,0.00003710841,0.9392712,0.000104170496,0.0003707485,0.000066664674],"about_ca_topic_score_codex":0.00029941212,"about_ca_topic_score_gemma":0.00020975765,"teacher_disagreement_score":0.052910276,"about_ca_system_score_codex":0.000014095164,"about_ca_system_score_gemma":0.00019309881,"threshold_uncertainty_score":0.34396496},"labels":[],"label_agreement":null},{"id":"W2039846441","doi":"10.1002/(sici)1099-1077(200004)15:3<199::aid-hup163>3.0.co;2-t","title":"The interaction between cytokines and neurotransmitters in depression and stress: possible mechanism of antidepressant treatments","year":2000,"lang":"en","type":"article","venue":"Human Psychopharmacology Clinical and Experimental","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Antidepressant; Mechanism (biology); Depression (economics); Animal models of depression; Psychology; Stress (linguistics); Chronic stress; Neuroscience; Pharmacology; Psychotherapist; Medicine; Hippocampus; Philosophy","score_opus":0.0501237004069989,"score_gpt":0.399544832697158,"score_spread":0.34942113229015914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039846441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99836296,0.0005406206,0.0000011422223,0.00014620538,0.00017305436,0.0002636632,0.000014062738,0.000017548326,0.00048075453],"genre_scores_gemma":[0.9977266,0.0016846801,0.000012191041,0.0004146959,0.00005031874,0.000025010695,0.0000018362989,0.000010055812,0.00007460456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987068,0.00023108034,0.00038544709,0.0004161915,0.000083412,0.00017706888],"domain_scores_gemma":[0.9993801,0.00036023054,0.00007521709,0.00009198547,0.000003852354,0.00008862747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010890548,0.0001393373,0.00021181234,0.00004783125,0.00021836405,0.000029689843,0.0001032379,0.00007711672,0.000112319365],"category_scores_gemma":[0.000010340643,0.00009814751,0.000039673025,0.000056363777,0.00055490766,0.00012919563,0.000046953264,0.00017786688,0.000002045233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022208064,0.00087694207,0.24161384,0.000021542744,0.000042421518,0.000032035685,0.00096735184,0.0000024935707,0.6976944,0.00024440934,0.00016458836,0.05611915],"study_design_scores_gemma":[0.016277075,0.0010479967,0.40063843,0.00007273183,0.00003920018,0.00003052906,0.00061341864,0.0002880791,0.5785677,0.0016401629,0.0005090677,0.00027563304],"about_ca_topic_score_codex":0.00002696997,"about_ca_topic_score_gemma":0.0000063374328,"teacher_disagreement_score":0.15902461,"about_ca_system_score_codex":0.0000041065664,"about_ca_system_score_gemma":0.0000039340857,"threshold_uncertainty_score":0.40023392},"labels":[],"label_agreement":null},{"id":"W2040169540","doi":"10.1016/s0165-0327(99)00076-2","title":"The in vitro immunosuppressive effects of moclobemide in healthy volunteers","year":2000,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"NIH Clinical Center","keywords":"Moclobemide; Proinflammatory cytokine; Cytokine; Pharmacology; Tumor necrosis factor alpha; Monoamine neurotransmitter; Medicine; Chemistry; Endocrinology; Internal medicine; Immunology; Serotonin; Receptor; Inflammation; Antidepressant","score_opus":0.004635938487889741,"score_gpt":0.24594390183056852,"score_spread":0.2413079633426788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040169540","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952088,0.0016995574,0.000023204506,0.00074447895,0.00028858602,0.00042254518,0.0000027994631,0.0000067960254,0.0016032173],"genre_scores_gemma":[0.99748546,0.0020653405,0.000020990723,0.000327637,0.000021039717,0.000013438833,2.2791258e-7,0.000018368319,0.00004748991],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979592,0.00056309934,0.0005178936,0.00020619456,0.0003591822,0.00039440717],"domain_scores_gemma":[0.99726295,0.0021458126,0.00029915062,0.00018341477,0.000041178595,0.00006747024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003896921,0.000177734,0.00035551723,0.0002782789,0.000090790156,0.000024432831,0.0004470406,0.00007397312,0.000026333124],"category_scores_gemma":[0.0015624361,0.00012785861,0.00017914384,0.00075392483,0.00029340872,0.00026767512,0.000028790193,0.00051394064,0.000006768013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009819094,0.0014499811,0.005706765,0.0001716859,0.00005206914,0.00012997226,0.0056627146,0.003491632,0.6234277,0.00035111356,0.00064213516,0.34909514],"study_design_scores_gemma":[0.01733921,0.0031602771,0.23625338,0.00051303336,0.000024353782,0.00007112203,0.0037689062,0.00092507363,0.7263529,0.008443862,0.002563319,0.0005846162],"about_ca_topic_score_codex":0.0002647287,"about_ca_topic_score_gemma":0.0004265481,"teacher_disagreement_score":0.34851053,"about_ca_system_score_codex":0.000120575765,"about_ca_system_score_gemma":0.00012402641,"threshold_uncertainty_score":0.5213923},"labels":[],"label_agreement":null},{"id":"W2040358998","doi":"10.3389/fpsyt.2015.00013","title":"Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models","year":2015,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Endophenotype; Schizophrenia (object-oriented programming); Neuroscience; Mechanism (biology); Psychology; Depression (economics); Animal models of depression; Psychiatry; Cognition; Hippocampus","score_opus":0.09095805022346064,"score_gpt":0.3367756546261261,"score_spread":0.24581760440266542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040358998","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022595064,0.98573,0.00036708193,0.00015802344,0.009018063,0.00072989694,0.00010166562,0.00013733505,0.0035320062],"genre_scores_gemma":[0.00006355377,0.99258024,0.0058758566,0.00019317622,0.00043870503,0.000060580045,0.000042858584,0.00017541515,0.0005696485],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966855,0.00044641155,0.0005679165,0.001350772,0.00044409744,0.00050527835],"domain_scores_gemma":[0.9985837,0.00008288905,0.000361807,0.00068975845,0.000014105185,0.0002677361],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019126834,0.00064107834,0.0014931692,0.00050244696,0.000110920795,0.0002883927,0.0006940104,0.00064019574,0.00007037149],"category_scores_gemma":[0.000097931275,0.0005606026,0.0002550753,0.0003654102,0.00024180801,0.0006656751,0.00020331427,0.0008453618,0.000079957535],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010697852,0.00009717834,0.00011652976,0.0009505842,0.000022945456,0.000016297063,0.00011421739,0.0000022803656,0.0000022190402,0.00011154923,0.13331988,0.86513937],"study_design_scores_gemma":[0.0016568903,0.00006165455,0.000018844265,0.009473074,0.00012729265,0.000019765697,0.0007004409,0.0005707171,0.000007917124,0.034602556,0.9518729,0.0008879803],"about_ca_topic_score_codex":0.00003212352,"about_ca_topic_score_gemma":0.00003855114,"teacher_disagreement_score":0.8642514,"about_ca_system_score_codex":0.0000826882,"about_ca_system_score_gemma":0.00036602505,"threshold_uncertainty_score":0.9996846},"labels":[],"label_agreement":null},{"id":"W2040757945","doi":"10.1097/bcr.0b013e318235836e","title":"Immunoprotective Role of Indoleamine 2,3-Dioxygenase in Engraftment of Allogenic Skin Substitute in Wound Healing","year":2012,"lang":"en","type":"review","venue":"Journal of Burn Care & Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Wound healing; Indoleamine 2,3-dioxygenase; Immune system; Immunology; Immune tolerance; Biology","score_opus":0.11779875361358223,"score_gpt":0.4070116609932307,"score_spread":0.2892129073796485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040757945","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.088852525,0.909689,0.000003161102,0.00001104651,0.00011358067,0.0010467875,0.000037307218,0.0000028367529,0.00024372384],"genre_scores_gemma":[0.28883392,0.7109271,0.000041762825,0.0000048981296,0.000100538025,0.000033997054,0.000002967103,0.00003533831,0.000019443101],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9938445,0.0017688533,0.0017380648,0.00035569957,0.0015521531,0.00074069836],"domain_scores_gemma":[0.9969475,0.00093443267,0.0010292714,0.00043065954,0.0004906962,0.00016738937],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0032910507,0.00032455343,0.0017781557,0.0024402316,0.00006125249,0.000034286848,0.0010522851,0.00033280786,0.00004876493],"category_scores_gemma":[0.0010101657,0.00025978833,0.00059381605,0.0020363561,0.00031532926,0.00021712144,0.00027871286,0.0025362791,0.000008016507],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030782766,0.0007212307,0.000024061927,0.009885922,0.00008706345,0.00026911922,0.004741995,0.0000507246,0.0273653,0.00011545494,0.000008202698,0.9564231],"study_design_scores_gemma":[0.007169745,0.0030869464,0.0014261302,0.05809305,0.00014418684,0.0007668366,0.017602375,0.000016059856,0.4192034,0.0008413564,0.49027902,0.0013708913],"about_ca_topic_score_codex":0.0004083219,"about_ca_topic_score_gemma":0.00026211032,"teacher_disagreement_score":0.9550522,"about_ca_system_score_codex":0.00084532594,"about_ca_system_score_gemma":0.0013152225,"threshold_uncertainty_score":0.99998546},"labels":[],"label_agreement":null},{"id":"W2041973311","doi":"10.3390/ijerph8010117","title":"Constitutive, but Not Challenge-Induced, Interleukin-10 Production Is Robust in Acute Pre-Pubescent Protein and Energy Deficits: New Support for the Tolerance Hypothesis of Malnutrition-Associated Immune Depression Based on Cytokine Production in vivo","year":2011,"lang":"en","type":"article","venue":"International Journal of Environmental Research and Public Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Immune system; Cytokine; Immunology; Malnutrition; Depression (economics); Medicine; Interleukin 10; Intensive care medicine; Internal medicine; Economics","score_opus":0.10292215072484849,"score_gpt":0.31588756942368285,"score_spread":0.21296541869883434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041973311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876574,0.00019130034,0.00015156023,0.011112085,0.00015011203,0.000537366,0.00008290424,0.0000034811899,0.00011378538],"genre_scores_gemma":[0.9974685,0.0017509406,0.00019403899,0.00024019452,0.000061218634,0.000034327106,0.0000033374938,0.000010084267,0.0002374002],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99799967,0.00024872858,0.00048654567,0.00029213715,0.00068768335,0.00028524417],"domain_scores_gemma":[0.99916244,0.0002283066,0.00029609332,0.00011222439,0.000074102034,0.00012681042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011302739,0.000109869005,0.00018088461,0.00044107687,0.00009991606,0.000035676454,0.00025018497,0.000056485667,0.00009077173],"category_scores_gemma":[0.00089648704,0.00008461683,0.000041090458,0.00015838008,0.00022873688,0.00033651682,0.000051184354,0.0002824323,4.5348622e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012275282,0.009511701,0.00692139,0.00014001617,0.00010184543,0.000052869087,0.0029097758,0.00019361661,0.6831033,0.00084552326,0.00083353213,0.28311116],"study_design_scores_gemma":[0.0049503203,0.0033690955,0.105711445,0.00075926335,0.0000044513454,0.000087494154,0.001070472,0.0010004762,0.8797913,0.00069341506,0.0023639149,0.00019834444],"about_ca_topic_score_codex":0.00021272845,"about_ca_topic_score_gemma":0.00010741046,"teacher_disagreement_score":0.2829128,"about_ca_system_score_codex":0.00032117602,"about_ca_system_score_gemma":0.00028484713,"threshold_uncertainty_score":0.34505743},"labels":[],"label_agreement":null},{"id":"W2042244259","doi":"10.2174/13816128113196660740","title":"Transcriptional Dys-regulation in Anxiety and Major Depression: 5-HT1A Gene Promoter Architecture as a Therapeutic Opportunity","year":2014,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"Canadian Institutes of Health Research","keywords":"Anxiety; Depression (economics); Gene; Promoter; Biology; Medicine; Psychology; Gene expression; Genetics; Psychiatry","score_opus":0.19201298931739302,"score_gpt":0.4013390565362857,"score_spread":0.2093260672188927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042244259","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008482476,0.97339684,0.02299075,0.0001702329,0.00055522716,0.0024035352,0.000051841893,0.00011270737,0.0002340389],"genre_scores_gemma":[0.0052541443,0.9932225,0.000222149,0.0005579735,0.0002240613,0.0002987593,0.000061212144,0.000073341354,0.0000858779],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954149,0.001754808,0.00066718296,0.0010665135,0.0005227151,0.00057389215],"domain_scores_gemma":[0.9984216,0.0005584125,0.00018861737,0.0003346201,0.000024856216,0.0004718688],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055900426,0.00063438545,0.00096894195,0.00027506065,0.00015284448,0.000114375674,0.00044416203,0.0003306836,0.00056529144],"category_scores_gemma":[0.0002141493,0.00048307015,0.00031068426,0.00043772097,0.00029961794,0.00014304888,0.00009001578,0.0012421272,0.00008047429],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071588176,0.0002749972,0.000004672635,0.003928682,0.000016322141,0.00000969237,0.000062410516,0.000005201714,0.0019256821,0.00063595874,0.000102813974,0.992962],"study_design_scores_gemma":[0.0011759795,0.00006807265,0.00007890243,0.0023963742,0.00025132368,0.00023962672,0.0000015432948,0.0010895485,0.001429931,0.0036490366,0.9889598,0.00065989327],"about_ca_topic_score_codex":6.9195585e-7,"about_ca_topic_score_gemma":4.060632e-7,"teacher_disagreement_score":0.99230206,"about_ca_system_score_codex":0.00007590623,"about_ca_system_score_gemma":0.00029363928,"threshold_uncertainty_score":0.9997621},"labels":[],"label_agreement":null},{"id":"W2042979672","doi":"10.1159/000048621","title":"A Case-Control Analysis of Nonsteroidal Anti-Inflammatory Drugs and Alzheimer’s Disease: Are They Protective?","year":2002,"lang":"en","type":"article","venue":"Neuroepidemiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Montreal General Hospital; Jewish General Hospital; McGill University","funders":"","keywords":"Medicine; Nonsteroidal; Disease; Drug; Medical prescription; Dementia; Internal medicine; Alzheimer's disease; Recall bias; Pharmacology; Pathology","score_opus":0.042988888268981805,"score_gpt":0.2703629045826967,"score_spread":0.22737401631371487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042979672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962862,0.0007279906,0.00021155109,0.0016417293,0.00011071318,0.00050771784,0.0001300194,0.0000901611,0.0002939234],"genre_scores_gemma":[0.99714684,0.00011416278,0.000022670629,0.002581582,0.000036231304,0.000051306622,8.790078e-7,0.000021023076,0.000025274416],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99684525,0.0013953882,0.00047460795,0.0007245358,0.00013860872,0.0004215908],"domain_scores_gemma":[0.99678487,0.0021564376,0.0003656125,0.0004592035,0.000033477096,0.00020041455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030480145,0.0002403484,0.00071977393,0.0003678837,0.00014549524,0.000012703195,0.00022063799,0.00009998403,0.00013762429],"category_scores_gemma":[0.0024433222,0.00020621173,0.00023897534,0.00042142428,0.0004454596,0.000113792,0.00008028685,0.0002881124,0.000018802495],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006777651,0.00086418324,0.8326709,0.00018065162,0.0015036786,0.007968781,0.0022920207,0.00557822,0.11744973,0.0056611123,0.0018331608,0.023319794],"study_design_scores_gemma":[0.0021769754,0.00021304915,0.9134963,0.000020641564,0.0014332728,0.00062555267,0.00016139592,0.07698981,0.0024812266,0.0011029904,0.00073710235,0.00056165335],"about_ca_topic_score_codex":0.000031525076,"about_ca_topic_score_gemma":0.00004240184,"teacher_disagreement_score":0.1149685,"about_ca_system_score_codex":0.000007343104,"about_ca_system_score_gemma":0.000013360533,"threshold_uncertainty_score":0.840907},"labels":[],"label_agreement":null},{"id":"W2042982960","doi":"10.1016/j.jad.2013.10.043","title":"Treatment-resistant depression: Definitions, review of the evidence, and algorithmic approach","year":2013,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":416,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université Laval; Bristol-Myers Squibb (Canada); McMaster University; University of Toronto; University Health Network","funders":"Bristol-Myers Squibb","keywords":"Aripiprazole; Major depressive disorder; Treatment-resistant depression; Psychosocial; Psychological intervention; Depression (economics); Pharmacotherapy; Quetiapine; Modalities; Medicine; Psychiatry; Psychology; Clinical psychology; Psychotherapist; Mood; Schizophrenia (object-oriented programming)","score_opus":0.08260955453904091,"score_gpt":0.33031484765159924,"score_spread":0.24770529311255834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042982960","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000052087224,0.996263,0.0000559088,0.0001095883,0.00022248138,0.0017482841,0.00003615519,0.000008811927,0.0015036471],"genre_scores_gemma":[0.00024066523,0.9991753,0.00017767341,0.00012813928,0.000056110366,0.00011738785,0.0000018420694,0.000039568204,0.00006329624],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99680185,0.001216169,0.0008525987,0.00038509295,0.00049537956,0.00024890673],"domain_scores_gemma":[0.99595577,0.0016275343,0.0017902298,0.00040754557,0.0001105526,0.00010838296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030683388,0.00045475864,0.0016207882,0.00022730877,0.00016988118,0.000043495776,0.00058286346,0.00015931042,0.000046169847],"category_scores_gemma":[0.0019867881,0.00023026252,0.0010352604,0.000756698,0.00037167367,0.00027726477,0.00011349881,0.00045630976,0.000006649151],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010886836,0.00029502428,0.000012703392,0.029218128,0.000102415666,0.0000038228486,0.00005082698,4.2913345e-7,0.000030859726,0.00019820503,0.001099,0.9689777],"study_design_scores_gemma":[0.0014232938,0.0009832325,0.00023491569,0.26576194,0.002096196,0.00074288284,0.00022084887,0.000008891925,0.00015219797,0.0011404263,0.72649616,0.000738995],"about_ca_topic_score_codex":0.000020876852,"about_ca_topic_score_gemma":0.000004921523,"teacher_disagreement_score":0.9682387,"about_ca_system_score_codex":0.00012449217,"about_ca_system_score_gemma":0.00041622698,"threshold_uncertainty_score":0.9389833},"labels":[],"label_agreement":null},{"id":"W2043049090","doi":"10.1007/s11920-011-0210-6","title":"Inflammatory Biomarkers in Depression: An Opportunity for Novel Therapeutic Interventions","year":2011,"lang":"en","type":"review","venue":"Current Psychiatry Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Depression (economics); Medicine; Context (archaeology); Psychiatry; Conceptualization; Psychological intervention; Disease; Clinical psychology; Intensive care medicine; Psychology; Psychotherapist; Internal medicine","score_opus":0.2696909647684732,"score_gpt":0.42220594714682985,"score_spread":0.15251498237835664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043049090","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008413271,0.98559004,0.0007221464,0.0000128852025,0.010238986,0.0023202195,0.00007779492,0.00015874229,0.0007950797],"genre_scores_gemma":[0.00024298104,0.9979359,0.00018934523,0.00007408286,0.00027447942,0.0008899812,0.00016996803,0.000112876776,0.00011038816],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99596906,0.0002736185,0.00172713,0.0012682395,0.00024291029,0.0005190711],"domain_scores_gemma":[0.99685526,0.00011503529,0.0014604073,0.0011931672,0.00003874828,0.0003373705],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006319255,0.0006032139,0.0010580368,0.00054962613,0.00017290917,0.00006950628,0.0005738775,0.00033212788,0.00018008401],"category_scores_gemma":[0.00029780885,0.00051266374,0.001265797,0.00048560064,0.00015994298,0.00030889505,0.00013434184,0.00056062837,0.000013024686],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015618334,0.0014397223,0.00041266915,0.017266447,0.000050456816,0.000020280908,0.000045979603,2.6823344e-7,0.0000062859067,0.0010295914,0.0010467,0.978666],"study_design_scores_gemma":[0.00034733827,0.00006658797,0.00021277703,0.014953395,0.00017542636,0.0003219396,0.000029246066,0.000009008777,0.0000045519246,0.0020366765,0.98120916,0.0006338672],"about_ca_topic_score_codex":0.0000038992416,"about_ca_topic_score_gemma":0.00004857907,"teacher_disagreement_score":0.9801625,"about_ca_system_score_codex":0.000070871036,"about_ca_system_score_gemma":0.00108436,"threshold_uncertainty_score":0.9997325},"labels":[],"label_agreement":null},{"id":"W2043060245","doi":"10.1176/appi.pn.2014.5b4","title":"Drug to Enhance NMDA Receptors Studied to Treat Negative Symptoms","year":2014,"lang":"en","type":"article","venue":"Psychiatric News","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"NMDA receptor; Glutamate receptor; Schizophrenia (object-oriented programming); Placebo; Receptor; Neuroscience; Medicine; Pharmacology; Drug; Clinical trial; Psychology; Psychiatry; Internal medicine","score_opus":0.010695814119335297,"score_gpt":0.27873016740381884,"score_spread":0.26803435328448355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043060245","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9408693,0.00006583819,0.0018202062,0.009171092,0.0025295538,0.0009888998,0.0000151465965,0.000278986,0.044261005],"genre_scores_gemma":[0.97437,0.00004950891,0.0020065296,0.013667594,0.0005177397,0.00012590781,0.0000010695483,0.000048888844,0.009212778],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977167,0.00020133783,0.00031264313,0.0008777996,0.00035123935,0.000540242],"domain_scores_gemma":[0.9986265,0.00036685367,0.00009806314,0.0005228806,0.000032015796,0.00035372106],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014094244,0.0002901145,0.00029356437,0.00026703396,0.00023660313,0.00006964501,0.0005478404,0.00005054951,0.00019841209],"category_scores_gemma":[0.0007433067,0.00025188908,0.00011287961,0.0016319266,0.00004963443,0.00011518776,0.00012012449,0.0001572346,0.0019080875],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042712447,0.0006491766,0.0031825942,0.00005462538,0.000016882112,0.0000018403977,0.0073711225,0.00017811578,0.047436856,0.0039844313,0.64403844,0.29265878],"study_design_scores_gemma":[0.0026585455,0.0014285787,0.0050327512,0.000052662785,0.000036161826,0.0000042771785,0.0013874149,0.00006729947,0.39124578,0.0067098434,0.58965427,0.0017223979],"about_ca_topic_score_codex":0.00016657056,"about_ca_topic_score_gemma":0.00026730107,"teacher_disagreement_score":0.34380892,"about_ca_system_score_codex":0.00005615444,"about_ca_system_score_gemma":0.0000327567,"threshold_uncertainty_score":0.9999933},"labels":[],"label_agreement":null},{"id":"W2043068812","doi":"10.1111/jnc.12771","title":"Astrocyte‐dependent protective effect of quetiapine on <scp>GABA</scp>ergic neuron is associated with the prevention of anxiety‐like behaviors in aging mice after long‐term treatment","year":2014,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Saskatchewan; University of Alberta","funders":"Canadian Institutes of Health Research; Health Canada; AstraZeneca Canada","keywords":"Neuroprotection; Astrocyte; GABAergic; Neuroscience; Programmed cell death; Pharmacology; Quetiapine; Neuron; Medicine; Chemistry; Biology; Inhibitory postsynaptic potential; Apoptosis; Psychiatry; Biochemistry; Central nervous system; Schizophrenia (object-oriented programming)","score_opus":0.007826495584800868,"score_gpt":0.2425735037100193,"score_spread":0.23474700812521843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043068812","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992934,0.000051714564,0.000034219673,0.000091679554,0.000058898495,0.00035662853,0.000010064454,0.000009200968,0.00009419639],"genre_scores_gemma":[0.999543,0.000041164254,0.0000050009344,0.00010236204,0.000037618538,0.000024616676,9.688737e-7,0.000025540663,0.00021970003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980889,0.00039162752,0.00044159775,0.0002965559,0.0005349865,0.00024633744],"domain_scores_gemma":[0.99818677,0.00052328035,0.00090894924,0.00023340175,0.00007381472,0.000073765],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028325416,0.00025343508,0.00039603608,0.00010592312,0.000044411354,0.00002410473,0.000278032,0.000082812054,0.000008161991],"category_scores_gemma":[0.0004754037,0.00016306357,0.00021563571,0.00025298866,0.00011103509,0.00010916688,0.000040229068,0.0004152145,8.2741315e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004379677,0.0005429562,0.010294298,0.00008252015,0.000023039816,0.000079085075,0.00043212678,0.00014550397,0.98703176,2.5693691e-7,0.000020630705,0.0009098326],"study_design_scores_gemma":[0.0022228537,0.0029199629,0.19914195,0.00029325436,0.00006146301,0.000111348345,0.000046227684,0.000022423394,0.7951102,0.00000452462,0.000011197429,0.000054588047],"about_ca_topic_score_codex":0.0000052920386,"about_ca_topic_score_gemma":0.000012035679,"teacher_disagreement_score":0.19192158,"about_ca_system_score_codex":0.00010155724,"about_ca_system_score_gemma":0.000054185057,"threshold_uncertainty_score":0.66495395},"labels":[],"label_agreement":null},{"id":"W2043390055","doi":"10.1021/np060111x","title":"Indoleamine 2,3-Dioxygenase Inhibitors from the Northeastern Pacific Marine Hydroid <i>Garveia </i><i>annulata</i>","year":2006,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Hydroid (botany); Indoleamine 2,3-dioxygenase; Fractionation; Biology; Chemistry; Hydrozoa; Stereochemistry; Cnidaria; Biochemistry; Botany; Ecology; Coral; Chromatography; Tryptophan","score_opus":0.009397956959365175,"score_gpt":0.20411966941079818,"score_spread":0.194721712451433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043390055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882666,0.0017477653,0.0000036526578,0.0071789064,0.0017120917,0.00022871369,0.000022648508,0.00003728122,0.00080234796],"genre_scores_gemma":[0.99499846,0.00006326204,0.0001509387,0.00091554056,0.0026099407,0.0000012968939,0.000010777367,0.00003182381,0.001217982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99766374,0.00019859285,0.00064624054,0.0003868317,0.00072613545,0.00037844657],"domain_scores_gemma":[0.9984534,0.00027278217,0.0005799197,0.0004296082,0.00017953754,0.000084749256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032664003,0.00026814395,0.0003084152,0.000116181785,0.00018864029,0.00013705919,0.0006490351,0.00007226633,0.000038664184],"category_scores_gemma":[0.0008324126,0.00016041983,0.00017219681,0.00062728475,0.00018865205,0.00053060893,0.00015376922,0.0007952292,0.000055816934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003508471,0.00028996938,0.002410547,0.000018635634,0.000019913055,0.00023972298,0.00018210895,0.000097477234,0.95728755,0.00009587203,0.0282547,0.010752654],"study_design_scores_gemma":[0.001617518,0.00016605553,0.0387045,0.00006020249,0.000015641914,0.00037426242,0.00012400298,0.000090214395,0.91678107,0.001775232,0.039959684,0.00033162083],"about_ca_topic_score_codex":0.00012079788,"about_ca_topic_score_gemma":0.000071415525,"teacher_disagreement_score":0.04050649,"about_ca_system_score_codex":0.000043366636,"about_ca_system_score_gemma":0.00008666633,"threshold_uncertainty_score":0.6541731},"labels":[],"label_agreement":null},{"id":"W2044680993","doi":"10.1016/j.nbd.2014.10.005","title":"Laminar and cellular analyses of reduced somatostatin gene expression in the subgenual anterior cingulate cortex in major depression","year":2014,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":101,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; National Institutes of Health","keywords":"Somatostatin; Anterior cingulate cortex; Neuroscience; Internal medicine; Endocrinology; Major depressive disorder; Cingulate cortex; Psychology; Prefrontal cortex; In situ hybridization; Biology; Neuropeptide; Gene expression; Medicine; Gene; Central nervous system; Receptor; Genetics; Cognition","score_opus":0.01953545116105946,"score_gpt":0.2796299787141329,"score_spread":0.26009452755307344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044680993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9994214,0.0001461566,0.000019473864,0.00010452685,0.00005074918,0.00019458056,0.000024255594,0.000009587934,0.000029232648],"genre_scores_gemma":[0.99959135,0.000042501477,0.000049477465,0.00027807537,0.000008456021,0.00000889896,0.000005824984,0.000008797746,0.00000663433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998464,0.00063509203,0.00029790966,0.00033574193,0.0000896029,0.00017769274],"domain_scores_gemma":[0.9992221,0.00029831863,0.00015898584,0.00025807155,0.000010551368,0.00005199193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013879304,0.00011814385,0.00022413745,0.00014412553,0.000036730835,0.0000056926037,0.00022662221,0.00004905893,0.000011900053],"category_scores_gemma":[0.00033415912,0.00008240247,0.00004638311,0.00018080774,0.00026727852,0.000052194067,0.000081752005,0.00009272291,0.0000010700364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002905957,0.00014882971,0.023005579,0.000044444725,8.39738e-7,0.000010097096,0.000265637,0.000022170838,0.97582126,0.000012392816,0.000015240118,0.00036294153],"study_design_scores_gemma":[0.0006703554,0.00007971924,0.3402928,0.000042328047,0.0000055847704,0.0000011179673,0.000048416186,0.00012496802,0.6585452,0.00013190713,0.000004511361,0.000053077332],"about_ca_topic_score_codex":0.000019990026,"about_ca_topic_score_gemma":0.000009061383,"teacher_disagreement_score":0.31728724,"about_ca_system_score_codex":0.0000026750454,"about_ca_system_score_gemma":0.000019214725,"threshold_uncertainty_score":0.33602753},"labels":[],"label_agreement":null},{"id":"W2044733885","doi":"10.1371/journal.pone.0120433","title":"Serum Levels of Inflammatory Markers in Depressed Elderly Patients with Diabetes and Mild Cognitive Impairment","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Uniwersytet Łódzki","keywords":"Internal medicine; Montreal Cognitive Assessment; Medicine; Depression (economics); Diabetes mellitus; Mood; Geriatric Depression Scale; Univariate analysis; Logistic regression; C-reactive protein; Gastroenterology; Cognitive impairment; Inflammation; Depressive symptoms; Clinical psychology; Endocrinology; Multivariate analysis; Disease","score_opus":0.03769301765651638,"score_gpt":0.217023356325,"score_spread":0.17933033866848364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044733885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989704,0.000036638863,0.0000011099139,0.000046959856,0.0000107962,0.0004753897,0.00007055421,0.000021741827,0.000366402],"genre_scores_gemma":[0.99967325,0.0000034534382,0.00008083284,0.00016912587,0.000004696273,0.000024516374,0.0000013885979,0.000012666114,0.000030093122],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990491,0.00007909291,0.00014214429,0.00021863151,0.0003123803,0.00019863206],"domain_scores_gemma":[0.9995404,0.00014378966,0.00007280135,0.00009613221,0.00005692023,0.000089965455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000808867,0.000102743106,0.00016076583,0.00008420535,0.000020836307,0.000013305025,0.00008155559,0.00003565694,0.000019097159],"category_scores_gemma":[0.00023141911,0.00008813167,0.000011520032,0.00014160348,0.00013535118,0.00014996537,0.00004715386,0.00007690453,0.0000047641156],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029372994,0.0013690246,0.9795977,0.00012541414,0.000031568074,0.0000034274735,0.0009287244,0.000002497293,0.016318893,0.000009010111,0.000019899633,0.0013001459],"study_design_scores_gemma":[0.0033537962,0.00051592116,0.78801525,0.00023600052,0.000011922405,3.8571994e-8,0.00020448976,0.00006151086,0.20741151,0.00008286202,7.817401e-7,0.000105928484],"about_ca_topic_score_codex":0.0000033954354,"about_ca_topic_score_gemma":0.00001678587,"teacher_disagreement_score":0.19158243,"about_ca_system_score_codex":0.00001592573,"about_ca_system_score_gemma":0.000037543734,"threshold_uncertainty_score":0.3593905},"labels":[],"label_agreement":null},{"id":"W2044757846","doi":"10.1371/journal.pone.0090439","title":"Suppression of Immunodominant Antitumor and Antiviral CD8+ T Cell Responses by Indoleamine 2,3-Dioxygenase","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Western University","funders":"National Cancer Institute; Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Indoleamine 2,3-dioxygenase; Kynurenine; Biology; FOXP3; Subdominant; Influenza A virus; Immunology; Antigen; Cytotoxic T cell; Epitope; Immunodominance; CD8; Virus; Virology; Immune system; In vitro; Genetics; Tryptophan","score_opus":0.02536459755828014,"score_gpt":0.22416942802038714,"score_spread":0.198804830462107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044757846","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981668,0.00032856452,0.000025107996,0.0001118338,0.000030459592,0.00018116641,0.00005257324,0.000040178053,0.0010633046],"genre_scores_gemma":[0.9982641,0.00025144295,0.0002640346,0.00016478084,0.000019407531,0.0000055363453,0.0000039549186,0.000019448247,0.0010073028],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987914,0.0002002487,0.00020605777,0.00030583487,0.0002702286,0.00022624881],"domain_scores_gemma":[0.9992059,0.00033162397,0.00011309796,0.00027185766,0.000021993766,0.00005553379],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016405384,0.00013371572,0.00025451448,0.00008712029,0.00008097756,0.00002168169,0.00018443445,0.000051835883,0.000035807087],"category_scores_gemma":[0.00069910684,0.00011363115,0.000033102882,0.00014239055,0.00020118651,0.00011037333,0.00010751252,0.00010869914,0.000025972542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032389525,0.00086625677,0.0004539783,0.00011361035,0.0000039655556,0.0000044706003,0.00010014284,9.59386e-8,0.99700403,0.000056120232,0.00037784068,0.0006955817],"study_design_scores_gemma":[0.0011793405,0.000277869,0.004009909,0.000109154935,0.000006988157,0.0000016822521,0.0000319951,0.000210844,0.9937679,0.00007188812,0.00019038572,0.00014201649],"about_ca_topic_score_codex":0.00001178277,"about_ca_topic_score_gemma":9.564665e-7,"teacher_disagreement_score":0.0035559305,"about_ca_system_score_codex":0.0000053389,"about_ca_system_score_gemma":0.000014811814,"threshold_uncertainty_score":0.46337438},"labels":[],"label_agreement":null},{"id":"W2044762426","doi":"10.1002/jcp.22220","title":"High expression of IMPACT protein promotes resistance to indoleamine 2,3‐dioxygenase‐induced cell death","year":2010,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Jurkat cells; Indoleamine 2,3-dioxygenase; Immune system; Cell biology; Apoptosis; Cytotoxic T cell; Biology; T cell; Chemistry; Cancer research; Immunology; Tryptophan; In vitro; Biochemistry","score_opus":0.01586867424673736,"score_gpt":0.2555487582135605,"score_spread":0.23968008396682314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044762426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988642,0.000043851785,0.00017431467,0.00014348574,0.000262236,0.00030606132,0.000010149168,0.000012569253,0.00018315885],"genre_scores_gemma":[0.9977231,0.0000049730124,0.0016768876,0.00009756953,0.00023567448,0.000005683613,0.0000012281507,0.000025117975,0.00022978177],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834305,0.0002203443,0.0005303975,0.00027195294,0.0003077054,0.0003265519],"domain_scores_gemma":[0.99851817,0.00013471204,0.00066343945,0.000356358,0.00013768472,0.00018963516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002458831,0.00020269585,0.00045629742,0.00020747539,0.000066676905,0.000015016266,0.0005367939,0.00014582812,0.00015335633],"category_scores_gemma":[0.00054139545,0.00014444206,0.00020567283,0.0002627402,0.00008323132,0.00015365602,0.00008576023,0.00051559863,0.000017513266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048176985,0.00031513863,0.000012953479,0.000048592206,0.000004658673,0.000028458815,0.00013651898,0.000025633419,0.9984255,0.00017619609,0.00021757947,0.00012700599],"study_design_scores_gemma":[0.00086575915,0.00079899933,0.0041454504,0.00006513028,0.0000035821938,0.000011569669,0.000022665638,0.0000069072066,0.991859,0.0018556819,0.00021849493,0.00014674758],"about_ca_topic_score_codex":0.000008075314,"about_ca_topic_score_gemma":0.000004020779,"teacher_disagreement_score":0.0065664826,"about_ca_system_score_codex":0.000020424184,"about_ca_system_score_gemma":0.00012779367,"threshold_uncertainty_score":0.5890177},"labels":[],"label_agreement":null},{"id":"W2045520507","doi":"10.1016/j.bbr.2006.10.033","title":"Investigating the hedonic effects of interferon-α on female rats using brain-stimulation reward","year":2006,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Stimulation; Psychology; Neuroscience; Brain stimulation reward; Brain stimulation; Developmental psychology; Central nervous system","score_opus":0.16236506681106955,"score_gpt":0.3931082258705254,"score_spread":0.23074315905945586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045520507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949319,0.000054702417,0.000058902926,0.0032254935,0.00014967378,0.0008402912,0.0000060165885,0.00006238294,0.0006706556],"genre_scores_gemma":[0.9982513,0.0000018721327,0.00011283748,0.0006410172,0.00009186992,0.000031861455,0.0000058166665,0.00003741861,0.0008259925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961441,0.0012685511,0.00036437286,0.00051012984,0.0010479173,0.00066490745],"domain_scores_gemma":[0.9939131,0.0052665696,0.0001253507,0.0004912497,0.00010667669,0.00009704107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00120255,0.00019357572,0.00021010537,0.00028466762,0.000538985,0.00013186788,0.0005792677,0.000110848785,0.00003920216],"category_scores_gemma":[0.0039160717,0.00014450948,0.000111810405,0.0009782765,0.00075822277,0.00017811112,0.00022882222,0.0006514007,0.000041844476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044819513,0.00013805971,0.009566463,0.00006315656,0.000002190839,0.00001873456,0.00034633683,0.00069914584,0.98251104,0.0023870254,0.002196001,0.002027016],"study_design_scores_gemma":[0.000821335,0.00055977324,0.09391238,0.00025474353,0.0000050185026,0.000010437681,0.00019609906,0.0033460627,0.89870214,0.0018719333,0.000109614775,0.00021044332],"about_ca_topic_score_codex":0.0007185535,"about_ca_topic_score_gemma":0.00007555494,"teacher_disagreement_score":0.08434592,"about_ca_system_score_codex":0.0001306085,"about_ca_system_score_gemma":0.00012277975,"threshold_uncertainty_score":0.5892925},"labels":[],"label_agreement":null},{"id":"W2045969502","doi":"10.3109/15622975.2014.984631","title":"The role of genetic variation across IL-1β, IL-2, IL-6, and BDNF in antipsychotic-induced weight gain","year":2015,"lang":"en","type":"article","venue":"The World Journal of Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Health Sciences Centre; University Health Network; Sunnybrook Health Science Centre; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Multifactor dimensionality reduction; Internal medicine; Antipsychotic; Single-nucleotide polymorphism; Brain-derived neurotrophic factor; Weight gain; Genotype; Endocrinology; Biology; Medicine; Oncology; Schizophrenia (object-oriented programming); Psychology; Neurotrophic factors; Genetics; Gene; Psychiatry; Receptor; Body weight","score_opus":0.034500576638817324,"score_gpt":0.29207627857376967,"score_spread":0.25757570193495233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045969502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908678,0.0017683965,0.00005421196,0.005225427,0.0010166689,0.00016550011,0.000010572731,0.00001040886,0.0008809917],"genre_scores_gemma":[0.9980455,0.00052011036,0.00036060493,0.00075429684,0.00024925833,0.0000021603119,2.2222886e-7,0.000009131826,0.000058706497],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980379,0.00053304527,0.0006092921,0.0002129657,0.00028038392,0.0003264651],"domain_scores_gemma":[0.99859804,0.0004954415,0.00048785843,0.00024444767,0.000055766177,0.00011844155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011582258,0.00015768272,0.00025871696,0.000083058396,0.00017226802,0.000056178993,0.00059529115,0.00008701542,0.000014460753],"category_scores_gemma":[0.00040042694,0.00007539474,0.00010676414,0.00050119596,0.00032634934,0.000083777,0.00008211836,0.00043022243,0.000008458671],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0050550275,0.0017876934,0.20824811,0.000031879732,0.000088826266,0.00003225657,0.0042583565,0.00031195793,0.6534623,0.03401018,0.003791856,0.088921584],"study_design_scores_gemma":[0.0035750344,0.0011782472,0.75883526,0.000095887146,0.000019796022,0.00017266964,0.0021075062,0.00043853757,0.012922998,0.20958796,0.010735172,0.00033096137],"about_ca_topic_score_codex":0.000007772283,"about_ca_topic_score_gemma":0.000084441934,"teacher_disagreement_score":0.6405393,"about_ca_system_score_codex":0.000019628225,"about_ca_system_score_gemma":0.000069254005,"threshold_uncertainty_score":0.3074508},"labels":[],"label_agreement":null},{"id":"W2046297288","doi":"10.2353/ajpath.2008.070456","title":"Adoptively Transferred Dendritic Cells Restore Primary Cell-Mediated Inflammatory Competence to Acutely Malnourished Weanling Mice","year":2008,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Immune system; Immunology; Weanling; Medicine; Dendritic cell; Wasting; CD8; Inflammation; Biology; Internal medicine","score_opus":0.01779548249423927,"score_gpt":0.2327575212391953,"score_spread":0.21496203874495604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046297288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960911,0.00012099236,0.0018860066,0.0005541567,0.000425378,0.00017292668,0.000024542134,0.000047491456,0.00067738205],"genre_scores_gemma":[0.98861283,0.0003733983,0.0063611767,0.0044080643,0.00012317895,0.0000046074747,0.0000013991482,0.00004013252,0.00007519936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99739915,0.0005296945,0.0006899979,0.00040332667,0.00042117128,0.0005566779],"domain_scores_gemma":[0.9981871,0.00063276564,0.0004537726,0.000231191,0.00014006264,0.0003550659],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026178284,0.00026299278,0.00060855434,0.00038469158,0.00017569405,0.00001833629,0.000689481,0.00007725013,0.000034024506],"category_scores_gemma":[0.0003125132,0.00024878653,0.00018516167,0.00063200586,0.0009585633,0.0002199249,0.000061935214,0.0005678356,0.00009159835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033509548,0.00016536827,0.0010444365,0.000015763899,0.00000803292,0.007348197,0.002723957,0.00016754988,0.98637325,0.000016496673,0.0005578064,0.0012440473],"study_design_scores_gemma":[0.0048347395,0.0066197794,0.1685323,0.00019534693,0.000081567254,0.01903141,0.003691866,0.00010574959,0.78996974,0.00010966318,0.005477885,0.0013499523],"about_ca_topic_score_codex":0.0000053845215,"about_ca_topic_score_gemma":0.000002739384,"teacher_disagreement_score":0.1964035,"about_ca_system_score_codex":0.00008212229,"about_ca_system_score_gemma":0.0003204508,"threshold_uncertainty_score":0.9999964},"labels":[],"label_agreement":null},{"id":"W2047068897","doi":"10.1016/j.nbd.2010.11.004","title":"Broadening our horizons: Gene expression profiling to help better understand the neurobiology of suicide and depression","year":2010,"lang":"en","type":"review","venue":"Neurobiology of Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Neuroscience; Depression (economics); Gene; Gene expression profiling; Gene expression; Biology; Psychology; Computational biology; Bioinformatics; Genetics","score_opus":0.05539285414230284,"score_gpt":0.3240784469994108,"score_spread":0.26868559285710797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047068897","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3970483,0.59738845,0.00009960252,0.0005980637,0.0014719417,0.0026673763,0.0005595971,0.0000998275,0.00006686951],"genre_scores_gemma":[0.11184419,0.8857769,0.0003622841,0.0013517805,0.00027168158,0.00013256312,0.000075143,0.00012380448,0.000061693805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99659353,0.0010172265,0.00071452785,0.0010461616,0.00015212239,0.00047641547],"domain_scores_gemma":[0.99743766,0.0008749948,0.00061187055,0.00078120345,0.000044580866,0.00024970985],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017810919,0.00050178904,0.0011495185,0.00026805096,0.00018697165,0.00002098585,0.00080340466,0.0003908815,0.000013801558],"category_scores_gemma":[0.0011631404,0.0003180689,0.00032923624,0.00029770515,0.0004554788,0.000070150556,0.0005908081,0.00074982387,0.000010673799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00061519037,0.00036885662,0.001542503,0.007351336,0.00004653988,0.000030811414,0.00017111436,0.000017085858,0.7575752,0.0001832291,0.0012812883,0.23081681],"study_design_scores_gemma":[0.0033565636,0.0018601596,0.003771963,0.013300734,0.0016085419,0.00013370113,0.0004488342,0.000013623534,0.8128277,0.0010701194,0.15861548,0.0029925758],"about_ca_topic_score_codex":0.0000034204793,"about_ca_topic_score_gemma":0.0000023165978,"teacher_disagreement_score":0.28838843,"about_ca_system_score_codex":0.000011187478,"about_ca_system_score_gemma":0.00016469827,"threshold_uncertainty_score":0.99992716},"labels":[],"label_agreement":null},{"id":"W2047482781","doi":"10.1016/j.pnpbp.2011.11.011","title":"Systemic illness moderates the impact of N-acetyl cysteine in bipolar disorder","year":2011,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; Bristol-Myers Squibb Canada; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Stanley Medical Research Institute; Beyond Blue; Organon BioSciences; Geelong Region Medical Research Foundation; Novartis","keywords":"Comorbidity; Medicine; Bipolar disorder; Context (archaeology); Depression (economics); Psychiatry; Quality of life (healthcare); Placebo; Randomized controlled trial; Clinical trial; Internal medicine; Mood; Alternative medicine","score_opus":0.034411491201157385,"score_gpt":0.3190890789208362,"score_spread":0.2846775877196788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047482781","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839897,0.013602995,0.000009167908,0.00048512558,0.0008440284,0.0007601303,0.000020664378,0.000058030575,0.00023013508],"genre_scores_gemma":[0.99689084,0.0020789767,0.000051278483,0.0007436738,0.000056518486,0.00015313811,0.0000016581434,0.000017488677,0.000006453552],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974387,0.0007026339,0.00054395787,0.0006767837,0.000110583846,0.00052728615],"domain_scores_gemma":[0.99911225,0.00033289287,0.0002020926,0.00024302231,0.000020768914,0.00008898365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003168539,0.00031576966,0.0004201587,0.00019721503,0.00012701386,0.000016195965,0.0005649774,0.00024992033,0.00011950027],"category_scores_gemma":[0.0000969622,0.00017636712,0.00013307632,0.0006929457,0.0010400312,0.00010785108,0.0001354413,0.000571542,0.000007947691],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016610266,0.0010711554,0.97977275,0.00004353742,0.000014443225,0.000025329717,0.00039586113,0.000031956984,0.009416107,0.0010990048,0.00009216455,0.0063766916],"study_design_scores_gemma":[0.004620079,0.0018233488,0.9866942,0.000055959546,0.00000952044,0.00013487191,0.00022759374,0.00083337346,0.000746659,0.0043418165,0.0001379456,0.00037459034],"about_ca_topic_score_codex":0.00003300975,"about_ca_topic_score_gemma":0.000017920845,"teacher_disagreement_score":0.012901092,"about_ca_system_score_codex":0.000013325596,"about_ca_system_score_gemma":0.000043638098,"threshold_uncertainty_score":0.71920425},"labels":[],"label_agreement":null},{"id":"W2048477468","doi":"10.1097/tp.0000000000000661","title":"Immunoprotection and Functional Improvement of Allogeneic Islets in Diabetic Mice, Using a Stable Indoleamine 2,3-Dioxygenase Producing Scaffold","year":2015,"lang":"en","type":"article","venue":"Transplantation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Natural Sciences and Engineering Research Council of Canada","funders":"Canadian Institutes of Health Research","keywords":"Islet; FOXP3; Indoleamine 2,3-dioxygenase; Splenocyte; Population; Transplantation; Immune system; Medicine; Streptozotocin; Cancer research; Immunology; Biology; Diabetes mellitus; Internal medicine; Endocrinology","score_opus":0.041034004188205485,"score_gpt":0.24580837034622569,"score_spread":0.2047743661580202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048477468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99734473,0.000106653155,0.0019479776,0.000028082624,0.00010074586,0.0003763069,0.000013124334,0.000021459551,0.00006092366],"genre_scores_gemma":[0.999621,0.00004870292,0.00019248991,0.00005182328,0.000019039899,0.000020306126,0.000011468261,0.000010292232,0.000024886125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913675,0.000052353018,0.00021213475,0.00025666054,0.0001888799,0.00015319757],"domain_scores_gemma":[0.9997433,0.000033103053,0.00007691564,0.0000806451,0.000028046677,0.00003801202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020573693,0.00009364661,0.00010753143,0.0001529466,0.000043264172,0.000015497295,0.00003969639,0.00003990993,0.000009507007],"category_scores_gemma":[0.000037742466,0.000093900715,0.000017142907,0.0002333171,0.000042788168,0.0002118767,0.000007299342,0.00006381609,0.0000026880182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002999865,0.00007829294,0.0006808849,0.00013978462,0.0000029102353,0.0000037405584,0.0009225613,0.0018970569,0.994805,0.00002329099,0.000001807944,0.0011446828],"study_design_scores_gemma":[0.0017821332,0.00015482893,0.01952033,0.000059455357,0.000006481918,0.000016739847,0.00014767473,0.0014031426,0.97661924,0.00018601674,0.000004490745,0.000099443496],"about_ca_topic_score_codex":0.00021487293,"about_ca_topic_score_gemma":0.00008591456,"teacher_disagreement_score":0.018839445,"about_ca_system_score_codex":0.000044224846,"about_ca_system_score_gemma":0.00004946776,"threshold_uncertainty_score":0.382916},"labels":[],"label_agreement":null},{"id":"W2048631947","doi":"10.1027/0838-1925.12.4.178","title":"Herbal Tea Formula Practice,Nutritional Insufficiency and Impairment of Cell-MediatedImmunity in an Infant with Pseudomonas aeruginosaSepsis","year":2000,"lang":"en","type":"article","venue":"Allergy & Clinical Immunology International - Journal of the World Allergy Organization","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pseudomonas aeruginosa; Sepsis; Medicine; Immunity; Immune system; Immunology; Intensive care medicine; Pediatrics; Biology; Bacteria","score_opus":0.014297493155673975,"score_gpt":0.29116328689691007,"score_spread":0.2768657937412361,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048631947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99377716,0.0001950554,0.000098918434,0.004539113,0.0005498663,0.00014889048,0.00001025643,0.000016672608,0.00066408975],"genre_scores_gemma":[0.99519134,0.0022381227,0.0006955656,0.0014969676,0.00013035488,0.000003019667,0.000013011095,0.000024062372,0.0002075896],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99699956,0.0006848972,0.0012043399,0.00028552758,0.00059512886,0.00023056273],"domain_scores_gemma":[0.99727905,0.0009006096,0.0009381904,0.00023124147,0.0005649625,0.000085976244],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005854588,0.0002005199,0.00033077513,0.00030112162,0.00013627321,0.000050838404,0.0009817383,0.00013651044,0.0007380044],"category_scores_gemma":[0.0011814211,0.00014495249,0.00010558234,0.00074245105,0.00055843015,0.00071702147,0.00017124673,0.0006473782,0.000008139622],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.030536028,0.09668053,0.18805014,0.00007725988,0.004876513,0.00097431254,0.010947062,0.027579254,0.5511355,0.043665826,0.0053884834,0.04008911],"study_design_scores_gemma":[0.016930506,0.0041137724,0.8842364,0.00037495664,0.000074000214,0.0011251552,0.0012243589,0.0007833174,0.06594588,0.0019298306,0.022556672,0.0007051901],"about_ca_topic_score_codex":0.000060492912,"about_ca_topic_score_gemma":0.00030417467,"teacher_disagreement_score":0.69618624,"about_ca_system_score_codex":0.000090947105,"about_ca_system_score_gemma":0.0002513129,"threshold_uncertainty_score":0.80806303},"labels":[],"label_agreement":null},{"id":"W2049234823","doi":"10.1007/s12017-010-8140-8","title":"Mood Disorders and Obesity: Understanding Inflammation as a Pathophysiological Nexus","year":2010,"lang":"en","type":"review","venue":"NeuroMolecular Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":164,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill University; University Health Network","funders":"","keywords":"Resistin; Mood disorders; Bipolar disorder; Allostatic load; Adiponectin; Adipokine; Insulin resistance; Leptin; Mood; Medicine; Obesity; Bioinformatics; Psychology; Internal medicine; Neuroscience; Clinical psychology; Psychiatry; Biology; Anxiety","score_opus":0.06399031839923969,"score_gpt":0.3130887523842647,"score_spread":0.24909843398502501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049234823","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016623893,0.98307145,0.0007660345,0.0008271954,0.0009377296,0.0016948638,0.000012871179,0.00029814546,0.010729347],"genre_scores_gemma":[0.0063375286,0.99251384,0.000019799521,0.0006074565,0.0002678112,0.000054877677,0.000033237604,0.00008491786,0.00008051504],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969096,0.00052200205,0.0005436551,0.0010401695,0.00052915065,0.00045541418],"domain_scores_gemma":[0.99828124,0.0005768824,0.00033729651,0.0005406039,0.0000143191055,0.0002496808],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018652626,0.00060854194,0.0012482938,0.00031159073,0.00023232856,0.000059700535,0.0004330655,0.0004668941,0.00009328794],"category_scores_gemma":[0.0021127358,0.0004404756,0.00023528465,0.0005984948,0.0006425811,0.0001007996,0.00020225166,0.001135176,0.000070148955],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015135678,0.00009771427,0.0000010085184,0.0038876685,0.000021311134,0.0003679984,0.00023430568,6.6064774e-7,0.030007647,0.019164592,0.00009738856,0.9461046],"study_design_scores_gemma":[0.001218227,0.00090321095,0.000018370461,0.0038838221,0.0003583635,0.00051009597,0.00009857541,0.000053186388,0.00029119386,0.029028144,0.9627561,0.00088072376],"about_ca_topic_score_codex":0.000009866856,"about_ca_topic_score_gemma":0.000011996622,"teacher_disagreement_score":0.9626587,"about_ca_system_score_codex":0.00004808345,"about_ca_system_score_gemma":0.000095105344,"threshold_uncertainty_score":0.9998047},"labels":[],"label_agreement":null},{"id":"W2049777942","doi":"10.1016/j.bbr.2012.07.026","title":"Novel therapeutic targets in depression: Minocycline as a candidate treatment","year":2012,"lang":"en","type":"review","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":189,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre; University Health Network; University of Toronto","funders":"","keywords":"Minocycline; Antidepressant; Neuroscience; Mood; Mood disorders; Monoamine neurotransmitter; Depression (economics); Medicine; Bioinformatics; Psychology; Psychiatry; Anxiety; Hippocampus; Biology; Internal medicine; Receptor; Serotonin","score_opus":0.3786694960846065,"score_gpt":0.47717027235681947,"score_spread":0.09850077627221299,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049777942","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010016316,0.9944782,0.00000419118,0.00031463013,0.00027437427,0.002477474,0.00017564661,0.00007957987,0.0011942288],"genre_scores_gemma":[0.006846024,0.9830544,0.00004692594,0.00021242157,0.00018725567,0.0010235853,0.00014352564,0.00013685746,0.008348989],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99371237,0.0014456908,0.0007358873,0.001214742,0.0011604399,0.0017308935],"domain_scores_gemma":[0.99627846,0.0021029909,0.00018565737,0.00094115135,0.000051829167,0.00043991522],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0010397446,0.00068202725,0.0013168536,0.00094443525,0.0003114892,0.00016904256,0.0011137247,0.0005204506,0.0009880805],"category_scores_gemma":[0.00054159004,0.0004752995,0.00047771723,0.0013599887,0.0003887537,0.0002011956,0.00038926274,0.0013201893,0.00096051657],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038151673,0.000924973,0.00017102732,0.000621604,0.00001504485,0.00021230144,0.0002426545,1.3099285e-7,0.0009821609,0.00013304004,0.00040251954,0.9962564],"study_design_scores_gemma":[0.0011819897,0.00023964289,0.00056259584,0.0015860117,0.00006893212,0.00021815406,0.000058143734,0.0000043381615,0.0008461299,0.00006254058,0.9945844,0.0005871181],"about_ca_topic_score_codex":0.0013765427,"about_ca_topic_score_gemma":0.0005368476,"teacher_disagreement_score":0.99566925,"about_ca_system_score_codex":0.0006424687,"about_ca_system_score_gemma":0.00064453005,"threshold_uncertainty_score":0.99992514},"labels":[],"label_agreement":null},{"id":"W2050406083","doi":"10.2174/1381612053381611","title":"Multiple Mechanisms of Cytokine Action in Neurodegenerative and Psychiatric States: Neurochemical and Molecular Substrates","year":2005,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Neurochemical; Proinflammatory cytokine; Microglia; Neurodegeneration; Neuroinflammation; Neuroscience; Cytokine; Tumor necrosis factor alpha; Neurotoxin; Disease; Medicine; Immunology; Inflammation; Psychology; Pathology; Internal medicine","score_opus":0.18048690771819584,"score_gpt":0.409723292864976,"score_spread":0.22923638514678016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050406083","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002300142,0.9899041,0.006118684,0.00005959969,0.0002854905,0.0012020308,0.00007091856,0.000047543137,0.0000114947525],"genre_scores_gemma":[0.016303796,0.9829969,0.0003962543,0.000111387584,0.00004799835,0.00007548794,0.000018045082,0.000047285,0.0000028444094],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971627,0.00071183813,0.00061460666,0.0008498791,0.00026950974,0.00039144384],"domain_scores_gemma":[0.9986223,0.00075676996,0.00020819492,0.00017407678,0.000022309125,0.00021637371],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001801252,0.00047544908,0.0008494253,0.00029025864,0.00005175728,0.00005032185,0.00022644376,0.00016471655,0.000019870226],"category_scores_gemma":[0.00028525697,0.00041101157,0.00013404748,0.0005737197,0.00026175688,0.00012663192,0.00010044817,0.0007318411,0.0000066362377],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006822354,0.0003940882,0.0000021134376,0.004130507,0.000010649317,0.00001917255,0.000033187756,0.000024325074,0.05759748,0.0010034218,0.000067690045,0.93664914],"study_design_scores_gemma":[0.005038484,0.00067342166,0.000025020518,0.0032152697,0.00082522386,0.00024252063,0.0000365874,0.023707248,0.5717545,0.0050535947,0.38722172,0.0022063921],"about_ca_topic_score_codex":6.370117e-7,"about_ca_topic_score_gemma":5.016618e-7,"teacher_disagreement_score":0.93444276,"about_ca_system_score_codex":0.00003210959,"about_ca_system_score_gemma":0.0000852094,"threshold_uncertainty_score":0.9998342},"labels":[],"label_agreement":null},{"id":"W2050725315","doi":"10.1126/scisignal.2003579","title":"Inflammatory Factors Contribute to Depression and Its Comorbid Conditions","year":2012,"lang":"en","type":"article","venue":"Science Signaling","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Canadian Institutes of Health Research","keywords":"Depression (economics); Medicine; Biology; Psychology; Clinical psychology; Psychiatry; Economics","score_opus":0.0325483570099361,"score_gpt":0.2952062304165358,"score_spread":0.26265787340659974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050725315","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981758,0.00011052988,0.00022758007,0.000116276824,0.00033112793,0.00020305133,0.000017588976,0.00008057626,0.00073744537],"genre_scores_gemma":[0.9991855,0.000004704413,0.00005026295,0.00064241816,0.000047006706,0.000009083261,8.5954406e-7,0.000007232664,0.00005295057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986108,0.000045363053,0.00013443487,0.00031020667,0.00038065494,0.00051853876],"domain_scores_gemma":[0.9991794,0.00020829267,0.000050478295,0.00013030836,0.00004105237,0.00039047375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041627142,0.00010745642,0.00009595453,0.00017861938,0.0006684318,0.00010386322,0.0002778069,0.00003173351,0.00009443656],"category_scores_gemma":[0.001096029,0.00008980968,0.00002354221,0.00056733267,0.00027405412,0.0008443038,0.00014240983,0.000097989556,0.00008395936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000029206121,0.000016353357,0.008502656,0.0000039415645,4.0549648e-7,0.0000010568401,0.000721982,0.000048676327,0.9878602,0.0026551588,0.00004609035,0.00014056744],"study_design_scores_gemma":[0.00015704626,0.000015794174,0.03223359,0.000024918429,0.0000019504741,0.0000057210777,0.00029314664,0.00018279428,0.96613306,0.00020336414,0.00060905155,0.00013956151],"about_ca_topic_score_codex":0.0000029368264,"about_ca_topic_score_gemma":9.218198e-7,"teacher_disagreement_score":0.023730932,"about_ca_system_score_codex":0.000029730309,"about_ca_system_score_gemma":0.000056820387,"threshold_uncertainty_score":0.51411045},"labels":[],"label_agreement":null},{"id":"W2050837748","doi":"10.2174/1871527313666141130204535","title":"Major Depressive Disorder and Type II Diabetes Mellitus: Mechanisms Underlying Risk for Alzheimer’s Disease","year":2015,"lang":"en","type":"review","venue":"CNS & Neurological Disorders - Drug Targets","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Disease; Medicine; Type 2 Diabetes Mellitus; Diabetes mellitus; Cognition; Neurodegeneration; Alzheimer's disease; Insulin resistance; Depression (economics); Major depressive disorder; Type 2 diabetes; Comorbidity; Cognitive decline; Psychiatry; Psychology; Dementia; Internal medicine; Endocrinology","score_opus":0.06917791278279671,"score_gpt":0.319807305493071,"score_spread":0.2506293927102743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050837748","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011697593,0.9907405,0.0005161409,0.00064488995,0.0010545101,0.0043020262,0.00083590817,0.00048793477,0.00024837337],"genre_scores_gemma":[0.009244778,0.9873845,0.00030844065,0.001189307,0.000090088855,0.0010936885,0.0002515747,0.00026466878,0.00017297469],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99272186,0.0012312199,0.0010029952,0.0027537192,0.00067083817,0.0016193463],"domain_scores_gemma":[0.995096,0.002027399,0.00082919316,0.0009849954,0.00010416865,0.0009582192],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00045040282,0.0015117998,0.0023386446,0.00033250908,0.00137363,0.00023542221,0.0013749448,0.00060526375,0.00016102089],"category_scores_gemma":[0.0031991762,0.001157223,0.0009100395,0.0007607611,0.0007782529,0.0003386176,0.0010345592,0.0011692157,0.00009589005],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002523664,0.00093340775,0.0001054298,0.0023117242,0.00021527614,0.00004870532,0.00015199576,0.00003867434,0.00001949099,0.0030346343,0.004102065,0.9887862],"study_design_scores_gemma":[0.0017376704,0.0007780022,0.00017487959,0.00040783867,0.0018500118,0.000005562929,0.000042490876,0.0006744,0.000013926792,0.06374801,0.92883766,0.0017295417],"about_ca_topic_score_codex":0.000011558552,"about_ca_topic_score_gemma":0.000024732177,"teacher_disagreement_score":0.9870567,"about_ca_system_score_codex":0.000037595015,"about_ca_system_score_gemma":0.00027191528,"threshold_uncertainty_score":0.99992645},"labels":[],"label_agreement":null},{"id":"W2052367168","doi":"10.1016/s0893-133x(99)00091-3","title":"Increased Temporal Cortex ER Stress Proteins in Depressed Subjects Who Died by Suicide","year":2000,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":104,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Medical Research Council; Medical Research Council Canada; Canadian Psychiatric Research Foundation","keywords":"Calreticulin; Schizophrenia (object-oriented programming); Bipolar disorder; Depression (economics); Mood disorders; Pathophysiology; Internal medicine; Major depressive disorder; Psychology; Mood; Endocrinology; Psychiatry; Medicine; Endoplasmic reticulum; Biology; Biochemistry","score_opus":0.016461520356104327,"score_gpt":0.28703365339317655,"score_spread":0.2705721330370722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052367168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865591,0.000120863,0.000005986453,0.0006890132,0.0004267643,0.0011124191,0.00009774658,0.00023039721,0.01075771],"genre_scores_gemma":[0.98684925,0.00019116842,0.000019719111,0.010541637,0.00009506699,0.00019156223,0.00001654673,0.0000707321,0.0020243465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99657995,0.00078264065,0.00046205302,0.0010282991,0.00032189165,0.00082517264],"domain_scores_gemma":[0.9988791,0.0003337298,0.00012160503,0.00038800703,0.000022633058,0.00025497653],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011568843,0.00036700245,0.00039428018,0.0002077291,0.00014162505,0.00005446159,0.00066926796,0.00016494705,0.003967855],"category_scores_gemma":[0.00015104133,0.00036945174,0.0000946098,0.00074944866,0.00029329513,0.00021772494,0.000059100505,0.0005831062,0.0003355235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012911175,0.0007797915,0.0078042806,0.00002310416,0.0000062425975,0.00044936436,0.000115184914,0.000052453008,0.97393507,0.000025094898,0.010220665,0.0052976543],"study_design_scores_gemma":[0.016877953,0.0006934031,0.23385075,0.000048483624,0.000024375351,0.00006929101,0.00003248372,0.0014509328,0.70291317,0.00025435004,0.04277176,0.0010130337],"about_ca_topic_score_codex":0.00033075304,"about_ca_topic_score_gemma":0.00015236836,"teacher_disagreement_score":0.27102187,"about_ca_system_score_codex":0.000037220627,"about_ca_system_score_gemma":0.000073499774,"threshold_uncertainty_score":0.9998757},"labels":[],"label_agreement":null},{"id":"W2052374541","doi":"10.1111/j.1524-475x.2008.00377.x","title":"Skin cells, but not T cells, are resistant to indoleamine 2, 3‐dioxygenase (IDO) expressed by allogeneic fibroblasts","year":2008,"lang":"en","type":"article","venue":"Wound Repair and Regeneration","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Immune system; Apoptosis; Human skin; Cell biology; Biology; Cancer research; Epidermis (zoology); Immune tolerance; Chemistry; Immunology; Tryptophan","score_opus":0.017493234908599112,"score_gpt":0.21556015651744642,"score_spread":0.1980669216088473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052374541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99709046,0.00051849906,0.0004894757,0.0005470755,0.0002985806,0.0004637504,0.000111531124,0.00021959693,0.00026100888],"genre_scores_gemma":[0.9861108,0.0004343484,0.0006895293,0.0016244296,0.00021306226,0.00004481423,0.000029358886,0.00003699079,0.010816673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99798286,0.0001683362,0.0003343024,0.0007767384,0.00037246733,0.00036527583],"domain_scores_gemma":[0.99912673,0.00007487103,0.0001196222,0.00040605752,0.00004564752,0.00022707702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011609396,0.0002700576,0.000233577,0.00012216128,0.0005304935,0.00007597953,0.00016844331,0.00015998096,0.000033806667],"category_scores_gemma":[0.000076572884,0.00023224122,0.000105047446,0.000276541,0.0001621107,0.00015875172,0.00007858725,0.00013744501,0.00004875197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001591127,0.00014119226,0.000010579248,0.000035748897,0.0000058800033,0.000039937,0.0003610763,0.00044615072,0.94426847,0.00004960423,0.05422074,0.00026152938],"study_design_scores_gemma":[0.00067833014,0.00018663383,0.00058704056,0.000025402267,0.000004132618,0.000016310758,0.00009863627,0.0004827876,0.9653525,0.00001908489,0.032234076,0.000315114],"about_ca_topic_score_codex":0.000050284776,"about_ca_topic_score_gemma":0.000093307404,"teacher_disagreement_score":0.021986665,"about_ca_system_score_codex":0.00004609495,"about_ca_system_score_gemma":0.000053869328,"threshold_uncertainty_score":0.94705224},"labels":[],"label_agreement":null},{"id":"W2052390712","doi":"10.1038/nm.3090","title":"Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression","year":2013,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":331,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute of General Medical Sciences; National Institute of Mental Health","keywords":"Nucleus accumbens; RAC1; Social defeat; Biology; Chromatin remodeling; Synaptic plasticity; Dendritic spine; Neuroscience; Cell biology; Chromatin; Genetics; Signal transduction; Dopamine; Gene","score_opus":0.010960648140949056,"score_gpt":0.26063840562120816,"score_spread":0.2496777574802591,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052390712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947351,0.0026706825,0.00014056038,0.0012637706,0.00017062403,0.00026093572,9.1616755e-7,0.000019907196,0.000737453],"genre_scores_gemma":[0.99909616,0.00039607915,0.00011566646,0.0002909059,0.00004746063,0.000007531827,0.0000025708675,0.000009481707,0.00003412599],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99907804,0.0000703384,0.00020762403,0.00025867598,0.00024046106,0.00014484955],"domain_scores_gemma":[0.9994558,0.00023337251,0.00008550429,0.00015068523,0.00002720826,0.00004739281],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010676638,0.00009923967,0.00016187153,0.00017293442,0.000035140027,0.0000058643536,0.00011493959,0.00016513653,0.00007094448],"category_scores_gemma":[0.0011147854,0.00007133519,0.000013164892,0.0002852733,0.00015423945,0.00011313805,0.000034195677,0.00029827785,0.0000019707907],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022707396,0.000044331424,0.005843678,0.00007373761,0.0000020350717,0.0000010057296,0.0008270958,0.00025757306,0.9309526,0.00022748514,0.00010622789,0.061641484],"study_design_scores_gemma":[0.0024902911,0.00016753796,0.58090407,0.0008827994,0.000013487426,0.0000063659736,0.0012005154,0.018916728,0.37907273,0.015959091,0.00012700395,0.00025940133],"about_ca_topic_score_codex":0.00011046017,"about_ca_topic_score_gemma":0.0000673543,"teacher_disagreement_score":0.57506037,"about_ca_system_score_codex":0.000009275358,"about_ca_system_score_gemma":0.000010419272,"threshold_uncertainty_score":0.29089645},"labels":[],"label_agreement":null},{"id":"W2052457877","doi":"10.1007/bf03033790","title":"Excitotoxicity of quinolinic acid: Modulation by endogenous antagonists","year":2000,"lang":"en","type":"article","venue":"Neurotoxicity Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":65,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Quinolinic acid; Kynurenic acid; Excitotoxicity; NMDA receptor; Neuroprotection; Chemistry; Neurotoxicity; Kynurenine; Pharmacology; Picolinic acid; Glutamate receptor; Kynurenine pathway; Biochemistry; Receptor; Biology; Tryptophan","score_opus":0.14821117729861108,"score_gpt":0.36475153995551013,"score_spread":0.21654036265689905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052457877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856806,0.000060974722,0.000019607964,0.00031835388,0.000069390764,0.0011065693,0.000083800616,0.000116045354,0.012544659],"genre_scores_gemma":[0.99819684,0.00028997273,0.000021614664,0.00043972043,0.000071284856,0.00007776568,0.0000061253263,0.000037875867,0.00085880223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957278,0.000965941,0.00042356495,0.0007473002,0.0013176991,0.0008177045],"domain_scores_gemma":[0.9985139,0.00044997383,0.00007701863,0.00065588905,0.00009385945,0.00020941002],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005959752,0.00020164429,0.0002762208,0.00022816422,0.00038449612,0.000080613456,0.0007852407,0.00015011232,0.0019293452],"category_scores_gemma":[0.0004977057,0.00020047123,0.00012134191,0.0010887722,0.000667778,0.00024954064,0.00012483729,0.0006761063,0.00041131984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001563581,0.0003914906,0.0003605724,0.00003388881,0.0000024535148,0.000022529543,0.00017323466,0.000021161375,0.9723582,0.0001626199,0.0017329324,0.024584537],"study_design_scores_gemma":[0.00069354416,0.00040679774,0.0024920083,0.000010556478,9.1285347e-7,0.000028921228,0.000029813813,0.00054839015,0.99000853,0.0007462947,0.004868739,0.0001655068],"about_ca_topic_score_codex":0.00016007623,"about_ca_topic_score_gemma":0.000017009103,"teacher_disagreement_score":0.02441903,"about_ca_system_score_codex":0.00005284425,"about_ca_system_score_gemma":0.0001182281,"threshold_uncertainty_score":0.998983},"labels":[],"label_agreement":null},{"id":"W2052938828","doi":"10.1016/j.jaci.2004.01.055","title":"Human eosinophils regulate T-cell functions through induction of indoleamine 2,3-dioxygenase","year":2004,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Eosinophil; Immunology; Cell biology; Biology; Chemistry; Biochemistry; Tryptophan","score_opus":0.04768888654134498,"score_gpt":0.31869432624627564,"score_spread":0.27100543970493063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052938828","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964541,0.000670941,0.00023203241,0.00085466163,0.00067401765,0.000053560827,0.0000021007552,0.000011496577,0.0010470648],"genre_scores_gemma":[0.9970076,0.0019247158,0.0001896543,0.00038554677,0.00016013175,6.738829e-7,7.787766e-7,0.000010372406,0.00032049816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984,0.0001895446,0.00090311497,0.00019446576,0.00013497761,0.0001779021],"domain_scores_gemma":[0.99883944,0.00016176794,0.0006680537,0.00018012652,0.000090998044,0.000059643917],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002490279,0.00011807846,0.00035277163,0.000102287886,0.00012873544,0.000011697996,0.0002006403,0.00023116184,0.00007678556],"category_scores_gemma":[0.00033457685,0.00009628586,0.00018810142,0.00017772419,0.0006100765,0.0002351648,0.0000615569,0.00054097746,0.000010335446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000535587,0.0015978738,0.000050621376,0.000009842831,0.00022750994,0.000051606286,0.0002521339,0.00018990798,0.985244,0.0059976233,0.00031036354,0.0055329762],"study_design_scores_gemma":[0.0159557,0.00934846,0.1168443,0.00015379832,0.000054839224,0.0008582544,0.0010888724,0.000004889207,0.786739,0.05260701,0.015902959,0.00044193788],"about_ca_topic_score_codex":0.00001690981,"about_ca_topic_score_gemma":0.00001723736,"teacher_disagreement_score":0.19850497,"about_ca_system_score_codex":0.000017272861,"about_ca_system_score_gemma":0.000074892014,"threshold_uncertainty_score":0.39264235},"labels":[],"label_agreement":null},{"id":"W2053563738","doi":"10.1016/j.cyto.2011.07.359","title":"CS09-7. Cross-talk between RIG-I dependent antiviral signalling and apoptosis","year":2011,"lang":"en","type":"article","venue":"Cytokine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Fluoxetine; Aggression; Biting; Alcohol; Serotonin; Pharmacology; Psychology; Medicine; Endocrinology; Internal medicine; Chemistry; Psychiatry; Biology; Biochemistry; Receptor; Ecology","score_opus":0.05282265809613305,"score_gpt":0.27529567162802243,"score_spread":0.2224730135318894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053563738","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98954,0.000055118264,0.00058301643,0.000050695224,0.00012358626,0.00014103939,0.000033739903,0.00012128567,0.00935152],"genre_scores_gemma":[0.9988776,0.000035008845,0.00024515996,0.0002822465,0.00010590379,0.00000739139,0.0000029577154,0.000024265728,0.00041946062],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874896,0.000051015275,0.00020185039,0.00044354852,0.00021054134,0.00034409575],"domain_scores_gemma":[0.9995086,0.00010631376,0.00006972653,0.00019439319,0.000018438623,0.00010250462],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120756675,0.00016984552,0.00018344156,0.00008508374,0.00017991725,0.000083242914,0.00025289904,0.00007946498,0.00018729077],"category_scores_gemma":[0.00013416966,0.00015382972,0.00005647863,0.00017885183,0.00022563574,0.00025159997,0.00012587555,0.0001565622,0.000093528724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070641014,0.00013106775,0.059616547,0.000038593585,0.000015136647,0.00003958394,0.000787698,0.0000025230127,0.9254397,0.0012536299,0.00016264849,0.012442191],"study_design_scores_gemma":[0.0006205514,0.000091884416,0.05603068,0.0000137597535,0.00000910599,0.0000060207703,0.000036430425,0.00003075071,0.94097817,0.0012904338,0.00068095955,0.00021125356],"about_ca_topic_score_codex":0.000043520682,"about_ca_topic_score_gemma":0.0000045752913,"teacher_disagreement_score":0.015538431,"about_ca_system_score_codex":0.000013221687,"about_ca_system_score_gemma":0.000014637388,"threshold_uncertainty_score":0.6272994},"labels":[],"label_agreement":null},{"id":"W2053664689","doi":"10.1021/ol900972j","title":"Plectosphaeroic Acids A, B, and C, Indoleamine 2,3-Dioxygenase Inhibitors Produced in Culture by a Marine Isolate of the Fungus <i>Plectosphaerella cucumerina</i>","year":2009,"lang":"en","type":"article","venue":"Organic Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Fungus; Chemistry; Stereochemistry; Microbiology; Biochemistry; Botany; Tryptophan; Biology; Amino acid","score_opus":0.0050063982340237045,"score_gpt":0.19634217887418803,"score_spread":0.19133578064016432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053664689","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932872,0.00030580332,0.000010688326,0.0055336356,0.00014569388,0.00048686084,0.000009167769,0.000056832985,0.00016410899],"genre_scores_gemma":[0.98955667,0.00017460468,0.000028254719,0.009975927,0.000048292983,0.0000071934305,0.000002547598,0.000029338407,0.00017718418],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822044,0.00012877399,0.00034205287,0.00056794035,0.0002920078,0.00044878465],"domain_scores_gemma":[0.99927753,0.0000516586,0.00015297567,0.0004141187,0.000015513435,0.00008821621],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109887726,0.00027770587,0.00027961985,0.00007333365,0.00010478755,0.0000403572,0.0004062134,0.000092030445,0.000069762355],"category_scores_gemma":[0.00028803965,0.00020548217,0.000069230904,0.0010886359,0.00017393284,0.00015633114,0.00014719277,0.00036441282,0.0000103450775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062832405,0.000120578086,0.0019233247,0.00002808175,0.000004256689,0.0000146575885,0.00051507616,0.0000024195517,0.99091387,0.000023140661,0.0048602265,0.0015315672],"study_design_scores_gemma":[0.001453358,0.0001431512,0.012398258,0.00003526059,0.0000045038314,0.00003799576,0.000029572557,0.000016787577,0.98450065,0.00004836495,0.0010923473,0.00023977371],"about_ca_topic_score_codex":0.00004679109,"about_ca_topic_score_gemma":0.000058150807,"teacher_disagreement_score":0.010474933,"about_ca_system_score_codex":0.00005063867,"about_ca_system_score_gemma":0.000036869114,"threshold_uncertainty_score":0.837932},"labels":[],"label_agreement":null},{"id":"W2054596199","doi":"10.6000/1929-5634.2013.02.04.8","title":"Dissociation of C-Reactive Protein Levels from Long-Chain Omega-3 Fatty Acid Status and Antidepressant Response in Adolescents with Major Depressive Disorder: An Open-Label Dose-Ranging Trial","year":2013,"lang":"en","type":"article","venue":"Journal of Nutritional Therapeutics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; National Institutes of Health","keywords":"Major depressive disorder; Internal medicine; Arachidonic acid; Fatty acid; Antidepressant; C-reactive protein; Omega 3 fatty acid; Depression (economics); Endocrinology; Eicosapentaenoic acid; Medicine; Gastroenterology; Polyunsaturated fatty acid; Inflammation; Docosahexaenoic acid; Chemistry; Biochemistry","score_opus":0.05353555996956328,"score_gpt":0.3135497984293106,"score_spread":0.2600142384597473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054596199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966743,0.00048322888,0.00083158526,0.0005869261,0.00006470958,0.0012023704,0.00014106666,0.000007853647,0.000007971862],"genre_scores_gemma":[0.9985283,0.00007132452,0.0009988528,0.00026257944,0.0000643261,0.000037133654,0.0000050071835,0.000026627202,0.0000058638075],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976293,0.0006711654,0.0005564974,0.0002718779,0.00058502634,0.00028613477],"domain_scores_gemma":[0.99846727,0.0003116193,0.0007410566,0.00014950249,0.00021020092,0.0001203512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035838032,0.00019599823,0.00037595304,0.000230332,0.00012162021,0.0001552161,0.00034570333,0.00010204813,0.000014067056],"category_scores_gemma":[0.00023695813,0.00015731498,0.00004407432,0.0002757319,0.00016773987,0.001078671,0.00007159169,0.00034596177,0.0000010452992],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0848499,0.0038958983,0.026877448,0.000036731217,0.00006316968,0.00003534008,0.0008137613,0.000027475886,0.8809743,0.000132251,0.0000024287936,0.002291289],"study_design_scores_gemma":[0.1041656,0.0025137176,0.7438995,0.0009258623,0.000039152426,0.000021411683,0.0006646278,0.00035838495,0.13818744,0.008917583,0.00001534175,0.00029136],"about_ca_topic_score_codex":0.00007582617,"about_ca_topic_score_gemma":0.000036261106,"teacher_disagreement_score":0.7427869,"about_ca_system_score_codex":0.00008413734,"about_ca_system_score_gemma":0.00015233559,"threshold_uncertainty_score":0.64151186},"labels":[],"label_agreement":null},{"id":"W2055260344","doi":"10.4155/fmc.10.297","title":"The Potential Use of Gabaergic Drugs in the Treatment of Asthma","year":2011,"lang":"en","type":"article","venue":"Future Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Asthma; GABAergic; Pharmacology; Medicine; Chemistry; Neuroscience; Biology; Internal medicine; Inhibitory postsynaptic potential","score_opus":0.022742096783538054,"score_gpt":0.23623903918998718,"score_spread":0.21349694240644912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055260344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954311,0.00047411036,0.0000049539963,0.0005069072,0.00018074024,0.00010714659,0.000007850335,0.000008101679,0.0032790846],"genre_scores_gemma":[0.9988806,0.00042373367,0.000024838697,0.00011079718,0.00023480103,0.000009518129,0.0000017567867,0.0000060766374,0.00030786524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911934,0.000053574502,0.00019820109,0.00016003956,0.00030270254,0.00016614098],"domain_scores_gemma":[0.99938226,0.00016081768,0.00010623676,0.00029978808,0.000017585164,0.000033330358],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009496614,0.00010812443,0.00013141024,0.000013402473,0.000056085577,0.0000064776573,0.00030182552,0.00005750956,0.00011219178],"category_scores_gemma":[0.000076969074,0.00005186116,0.00008076113,0.00016787504,0.00030780502,0.000032377324,0.000014934577,0.00010504169,0.0000019909853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00061660376,0.001095435,0.0007412054,0.00011401291,0.0000200599,0.000102349404,0.019251702,0.0000040129476,0.95253676,0.00062674895,0.0018590018,0.023032129],"study_design_scores_gemma":[0.0009221255,0.0002389508,0.009605325,0.000027447604,0.000012509354,0.00004314449,0.0067359847,0.000024232577,0.96721333,0.00024120562,0.014852516,0.00008323035],"about_ca_topic_score_codex":0.000046429395,"about_ca_topic_score_gemma":0.0000074193194,"teacher_disagreement_score":0.022948898,"about_ca_system_score_codex":0.000014719674,"about_ca_system_score_gemma":0.000035028286,"threshold_uncertainty_score":0.21148367},"labels":[],"label_agreement":null},{"id":"W2055503327","doi":"10.1371/journal.pone.0010967","title":"Prenatal Inflammation-Induced Hypoferremia Alters Dopamine Function in the Adult Offspring in Rat: Relevance for Schizophrenia","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Canadian Institutes of Health Research; Canadian Bureau for International Education","keywords":"Offspring; Dopamine; Nucleus accumbens; Endocrinology; Ventral tegmental area; Internal medicine; Neurochemical; Amphetamine; Prenatal cocaine exposure; Dopaminergic; Medicine; Biology; Pregnancy","score_opus":0.032327007798654106,"score_gpt":0.2360688914078746,"score_spread":0.2037418836092205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055503327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973479,0.0000096552585,0.000047394376,0.0011635871,0.00019491072,0.0007297473,0.0000051395887,0.000051232073,0.0004504429],"genre_scores_gemma":[0.99867046,0.000010747449,0.0005327228,0.00037193773,0.00014573471,0.00019900451,0.000005248134,0.000013935948,0.000050206418],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988638,0.000056798362,0.00025520826,0.00032152268,0.00024647758,0.00025618495],"domain_scores_gemma":[0.99914813,0.00042074345,0.00008682956,0.00028077594,0.000031187297,0.000032309355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020417868,0.00012114292,0.00013516626,0.00013184884,0.00007964466,0.000050047383,0.00028660422,0.00007200832,0.000010667485],"category_scores_gemma":[0.0023901805,0.00010250533,0.00003255721,0.00034491086,0.00004504274,0.00030470625,0.00002412152,0.0003839421,0.000023941402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023900789,0.00022812243,0.00053134275,0.000066186374,0.000002735696,0.0000027837973,0.00028793406,0.00001225175,0.9926421,0.0022461545,0.000010925822,0.0037304217],"study_design_scores_gemma":[0.0019410421,0.00008075425,0.0180994,0.00012453293,0.0000058464175,0.0000017266683,0.000078510435,0.0029424508,0.9751272,0.0013997296,0.000043372045,0.00015541715],"about_ca_topic_score_codex":0.000023088933,"about_ca_topic_score_gemma":0.00079160917,"teacher_disagreement_score":0.017568057,"about_ca_system_score_codex":0.00002322433,"about_ca_system_score_gemma":0.000030504616,"threshold_uncertainty_score":0.4180046},"labels":[],"label_agreement":null},{"id":"W2055568104","doi":"10.1038/tp.2014.56","title":"Association of trauma exposure with proinflammatory activity: a transdiagnostic meta-analysis","year":2014,"lang":"en","type":"review","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":206,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Defence Research and Development Canada; Western University","funders":"Nova Southeastern University","keywords":"Medicine; Meta-analysis; Biomarker; Population; Proinflammatory cytokine; Internal medicine; Clinical psychology; Interleukin; Inflammation; Psychiatry; Cytokine; Environmental health","score_opus":0.0690294989003811,"score_gpt":0.31835482743581095,"score_spread":0.24932532853542985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055568104","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001635428,0.99310845,0.001956306,0.0009423988,0.00018591882,0.0013140434,0.0005376633,0.00010167837,0.0016899685],"genre_scores_gemma":[0.0134302825,0.98214644,0.0017297165,0.00027435468,0.00029334574,0.00054853153,0.00019685918,0.00018350618,0.0011969536],"study_design_codex":"design_other","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99637043,0.00069409667,0.00082946516,0.0007628617,0.0010232108,0.00031993157],"domain_scores_gemma":[0.99696124,0.0014459561,0.0009911588,0.00044474975,0.00005910995,0.00009777463],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042661594,0.000549891,0.0030767387,0.0005580959,0.000104619714,0.00003930254,0.00038781675,0.00039371545,0.00067092426],"category_scores_gemma":[0.0000705751,0.00040102444,0.0035995578,0.0015191737,0.000091561276,0.00017289828,0.0000056419144,0.00046950416,0.000042641837],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039836645,0.003046712,0.00093092583,0.0634478,0.39179188,0.000015367492,0.00093040394,0.0018902961,0.0000490599,0.017093455,0.0016322231,0.5187735],"study_design_scores_gemma":[0.0014062158,0.0002918347,0.00091026595,0.0006360463,0.60799694,0.000015834077,0.000011065947,0.000057055873,0.000054342923,0.0013403958,0.3860265,0.0012534842],"about_ca_topic_score_codex":0.0000052245477,"about_ca_topic_score_gemma":0.00025005368,"teacher_disagreement_score":0.51752,"about_ca_system_score_codex":0.000033796437,"about_ca_system_score_gemma":0.00042627222,"threshold_uncertainty_score":0.99984413},"labels":[],"label_agreement":null},{"id":"W2056254518","doi":"10.1016/j.idairyj.2009.12.002","title":"Neuroimmune aspects of food intake","year":2009,"lang":"en","type":"article","venue":"International Dairy Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Affect (linguistics); Cognition; Motility; Function (biology); Neuroscience; Biology; Inflammation; Intestinal motility; Central nervous system; Brain function; Physiology; Psychology; Immunology; Cell biology; Communication","score_opus":0.027413277647892025,"score_gpt":0.27280328495519446,"score_spread":0.24539000730730243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056254518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8871878,0.00008529949,0.00058805186,0.0043294244,0.0014685524,0.000055891483,0.000012947953,0.00003516869,0.10623691],"genre_scores_gemma":[0.9976772,0.00006428631,0.000110567475,0.0016195317,0.00020061164,4.0848215e-7,9.393127e-7,0.0000065674876,0.00031987223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897856,0.000045281202,0.00027516016,0.00013730107,0.00042197117,0.00014175869],"domain_scores_gemma":[0.9995202,0.000072583774,0.00017454676,0.00010222502,0.00006878815,0.00006168315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000092576105,0.000085115214,0.00009599569,0.00016236186,0.000068024,0.00006367841,0.000496078,0.000028754866,0.000412469],"category_scores_gemma":[0.0004250066,0.00007571084,0.000103430866,0.00012647994,0.0000538116,0.00025061704,0.000030836174,0.00024119588,0.000036685466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012257541,0.0003375558,0.00013573487,0.0000024604683,0.000018725665,0.00011005823,0.00026795958,0.00013828365,0.82706183,0.11223881,0.0027719992,0.056793995],"study_design_scores_gemma":[0.002269201,0.0010663248,0.06424198,0.000077072844,0.0000067644987,0.0023222938,0.00011284693,0.00039980127,0.7345408,0.15491462,0.039769273,0.00027900212],"about_ca_topic_score_codex":0.0000010040219,"about_ca_topic_score_gemma":0.0000013898989,"teacher_disagreement_score":0.110489465,"about_ca_system_score_codex":0.000026820922,"about_ca_system_score_gemma":0.000046210975,"threshold_uncertainty_score":0.45162463},"labels":[],"label_agreement":null},{"id":"W2056547365","doi":"10.1503/jpn.090180","title":"Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder","year":2010,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Svenska Läkaresällskapet; Bertil Hållstens Forskningsstiftelse; Länsstyrelsen Östergötland; Vetenskapsrådet; Stockholms Läns Landsting; Karolinska Institutet; Ragnar Söderbergs stiftelse","keywords":"Kynurenic acid; Bipolar disorder; Schizophrenia (object-oriented programming); Cerebrospinal fluid; Internal medicine; Psychology; Kynurenine pathway; Medicine; Endocrinology; Kynurenine; Psychiatry; Glutamate receptor; Chemistry; Tryptophan; Lithium (medication)","score_opus":0.013310822633269485,"score_gpt":0.24616492078536115,"score_spread":0.23285409815209165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056547365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982248,0.00015042163,0.00009895913,0.00059713045,0.00074448955,0.00012405073,0.000019028861,0.0000032306634,0.00003791703],"genre_scores_gemma":[0.9991565,0.000044973283,0.00026232412,0.00049270026,0.000028453922,7.808314e-7,9.293205e-8,0.000007219085,0.0000069843186],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984589,0.000121957295,0.00044783996,0.0002109954,0.00055095914,0.00020933883],"domain_scores_gemma":[0.99905896,0.0000915143,0.0004964896,0.00021329045,0.00007323071,0.000066507135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003551836,0.0001288499,0.00020610125,0.00018330709,0.00010266813,0.00002864137,0.0006236379,0.000047347134,0.000018154911],"category_scores_gemma":[0.00034856165,0.000074789285,0.00006455823,0.00082947715,0.00056930643,0.00034882224,0.00003675764,0.0004217375,3.5945683e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018166477,0.00055256585,0.26822424,0.000028466362,0.0000010770541,0.0000021818767,0.00018612816,0.0000146641405,0.7286507,0.0014109535,0.000027937032,0.00071943476],"study_design_scores_gemma":[0.0012771924,0.0012132679,0.92847157,0.000039441788,0.000007955858,0.000050290168,0.00008603873,0.00004181352,0.067633644,0.00060528895,0.0004743592,0.00009914421],"about_ca_topic_score_codex":0.0000035893231,"about_ca_topic_score_gemma":0.00003621788,"teacher_disagreement_score":0.661017,"about_ca_system_score_codex":0.0000024205208,"about_ca_system_score_gemma":0.00012963625,"threshold_uncertainty_score":0.30498183},"labels":[],"label_agreement":null},{"id":"W2056757508","doi":"10.1017/s0033291712000190","title":"Non-steroidal anti-inflammatory drugs and efficacy of antidepressants in major depressive disorder","year":2012,"lang":"en","type":"article","venue":"Psychological Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute for Health and Care Research","keywords":"Major depressive disorder; Medicine; Psychiatry; Depression (economics); Antidepressant; Psychology; Anxiety; Cognition","score_opus":0.026689708232526387,"score_gpt":0.3183476968815173,"score_spread":0.29165798864899095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056757508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931009,0.0009907617,0.00006389223,0.0006252192,0.0003285789,0.00033198067,0.0000035569649,0.00003880927,0.0045163175],"genre_scores_gemma":[0.9985695,0.00024845533,0.000043827647,0.0009373603,0.00012617839,0.000015473082,0.0000013200241,0.000014177981,0.000043744327],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983495,0.00012270882,0.00038387981,0.00041943355,0.00028251673,0.00044194568],"domain_scores_gemma":[0.9989022,0.0004889581,0.00013532097,0.00028133768,0.000013965741,0.0001782269],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025863628,0.00019170725,0.00037821964,0.00014073511,0.000050950508,0.000005880879,0.00025593038,0.00012135487,0.00022180667],"category_scores_gemma":[0.00074880634,0.00012799155,0.000038339076,0.00028836608,0.00068923726,0.00014716965,0.000095059266,0.00024558103,0.000022994505],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003527511,0.0013692687,0.47455025,0.00009101143,0.0000099891595,0.000048745627,0.0027488226,0.000004090468,0.47721627,0.0006929167,0.0007629979,0.0421529],"study_design_scores_gemma":[0.005652595,0.00018252611,0.9777856,0.00009923259,0.000007634507,0.00002146646,0.00021941288,0.000020407122,0.01540184,0.0002530409,0.00020067274,0.00015560283],"about_ca_topic_score_codex":0.000012903724,"about_ca_topic_score_gemma":0.0000015932362,"teacher_disagreement_score":0.50323534,"about_ca_system_score_codex":0.0000061160627,"about_ca_system_score_gemma":0.0000022742913,"threshold_uncertainty_score":0.5219344},"labels":[],"label_agreement":null},{"id":"W2058488647","doi":"10.1016/j.jalz.2012.05.823","title":"P2‐118: Liver X receptors ligand and minocycline: Effectiveness of combined drug therapy in an Alzheimer's transgenic mouse model","year":2012,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"","keywords":"Minocycline; Neuroinflammation; Apolipoprotein E; Neuroprotection; Liver X receptor; Genetically modified mouse; Medicine; Neuropathology; Pharmacology; Transgene; Internal medicine; Disease; Biology; Nuclear receptor; Gene","score_opus":0.04431363206228949,"score_gpt":0.2814821280977374,"score_spread":0.23716849603544793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058488647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9673127,0.03147744,0.0000725964,0.00003788544,0.00022358689,0.0006767189,0.000016153426,0.000059059235,0.00012387574],"genre_scores_gemma":[0.9983077,0.0009787111,0.00033905948,0.0002243282,0.000029288467,0.000054304197,0.00001106432,0.00004935778,0.0000062005906],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99791235,0.0004489652,0.0003684732,0.0004882213,0.00027218155,0.0005098041],"domain_scores_gemma":[0.9990543,0.00025251525,0.000119731594,0.0003565034,0.00003109351,0.00018585852],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004886189,0.0003021105,0.00035312137,0.00016721741,0.000099117504,0.000034729983,0.0003238196,0.000107393316,0.000059343496],"category_scores_gemma":[0.000021842778,0.00028207176,0.00009952483,0.00027662332,0.00023536962,0.00067837903,0.000059541035,0.00017318013,0.000014306961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086427236,0.0016071441,0.020468783,0.000024641955,0.001285377,0.0000018330038,0.003856026,0.00018341915,0.94709134,0.00080779975,0.00015084294,0.023658514],"study_design_scores_gemma":[0.0025737202,0.00019391763,0.014507301,0.000017367627,0.00066307705,0.0000010895487,0.00008306825,0.0011756041,0.9801336,0.0002080697,0.00010461054,0.00033856984],"about_ca_topic_score_codex":0.000095722055,"about_ca_topic_score_gemma":0.000057176276,"teacher_disagreement_score":0.03304226,"about_ca_system_score_codex":0.000004056352,"about_ca_system_score_gemma":0.000032811615,"threshold_uncertainty_score":0.99996316},"labels":[],"label_agreement":null},{"id":"W2058846568","doi":"10.1016/j.jpsychores.2010.07.009","title":"Pain, sensory function, and neurogenic inflammatory response in young women with low mood","year":2010,"lang":"en","type":"article","venue":"Journal of Psychosomatic Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Mood; Subclinical infection; Depression (economics); Psychopathology; Psychology; Medicine; Mood disorders; Clinical psychology; Psychiatry; Internal medicine; Anxiety","score_opus":0.025400847022859305,"score_gpt":0.31275906103823176,"score_spread":0.2873582140153724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058846568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978398,0.000040836632,0.00006810524,0.0011831903,0.00021793415,0.00022609106,7.0088436e-7,0.000012375029,0.00041094425],"genre_scores_gemma":[0.99931294,0.000058360503,0.00012788174,0.00021299654,0.000089942325,0.00001480222,3.1528494e-8,0.000024064213,0.00015900159],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9961863,0.001639117,0.00046471157,0.00024321763,0.0009827547,0.0004838582],"domain_scores_gemma":[0.99740654,0.0016671275,0.00017941263,0.00031194108,0.00017928102,0.00025571685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0056221597,0.0001264243,0.00020361695,0.00071441935,0.00014061284,0.00013163943,0.00033666924,0.00008204241,0.00011420325],"category_scores_gemma":[0.0036734412,0.000093898925,0.00003541839,0.00074810814,0.0003566443,0.00032225042,0.000042423206,0.0012054485,0.000023049988],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006025521,0.00025361226,0.033693794,0.00008461643,0.000014783348,0.00016998127,0.00234543,0.000015117314,0.954817,0.00010815472,0.00026062227,0.0022113926],"study_design_scores_gemma":[0.003611758,0.0022816095,0.9775045,0.00014373775,0.0000027088238,0.000776358,0.002783825,0.0004543218,0.006419444,0.005393555,0.00042974006,0.00019846165],"about_ca_topic_score_codex":0.0000024202577,"about_ca_topic_score_gemma":0.000047124915,"teacher_disagreement_score":0.9483975,"about_ca_system_score_codex":0.000046469428,"about_ca_system_score_gemma":0.00019830433,"threshold_uncertainty_score":0.5237141},"labels":[],"label_agreement":null},{"id":"W2058897435","doi":"10.1038/jid.2011.467","title":"Application of an Indoleamine 2,3-Dioxygenase–Expressing Skin Substitute Improves Scar Formation in a Fibrotic Animal Model","year":2012,"lang":"en","type":"letter","venue":"Journal of Investigative Dermatology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Indoleamine 2,3-dioxygenase; Medicine; Immune system; Scars; Kynurenine; Catabolism; Wound healing; Immunology; Pathology; Tryptophan; Biology; Internal medicine; Metabolism; Biochemistry","score_opus":0.03454119276250287,"score_gpt":0.27030275664151776,"score_spread":0.2357615638790149,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058897435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97166026,0.00021652345,0.0028889973,0.024558729,0.0001061075,0.0004148573,0.00003522808,0.000018532555,0.000100794714],"genre_scores_gemma":[0.9529817,0.000020545607,0.0030556205,0.04353156,0.00030742315,0.000019880526,0.000034836805,0.000040147635,0.000008256577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969831,0.00057313085,0.0012394593,0.000300657,0.00045085925,0.00045280185],"domain_scores_gemma":[0.9969115,0.00027737065,0.002203423,0.0002848112,0.00018960118,0.00013327383],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000207218,0.0003472236,0.0007967071,0.0007817459,0.00007210971,0.00003690733,0.0005784028,0.0006077799,0.0000040026803],"category_scores_gemma":[0.0005237124,0.00031219094,0.00016214392,0.00039184012,0.00077093364,0.0014594818,0.00007282194,0.0015084919,0.0000065325053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000817882,0.000095346215,0.000012603057,0.00039525246,0.000013811863,0.0001456789,0.0013540215,0.00068963005,0.9892772,0.0002574229,0.0070819347,0.0005953127],"study_design_scores_gemma":[0.0009068825,0.00012220487,0.00050441944,0.00019193917,0.000018988108,0.0013069457,0.000105878746,0.035587877,0.95703053,0.0028331198,0.0011241649,0.00026702473],"about_ca_topic_score_codex":0.000012408645,"about_ca_topic_score_gemma":0.000010774638,"teacher_disagreement_score":0.034898248,"about_ca_system_score_codex":0.00010327411,"about_ca_system_score_gemma":0.00021134899,"threshold_uncertainty_score":0.999933},"labels":[],"label_agreement":null},{"id":"W2059166555","doi":"10.2217/pgs.13.154","title":"Integrative Mouse and Human mRNA Studies Using WGCNA Nominates Novel Candidate Genes Involved in the Pathogenesis of Major Depressive Disorder","year":2013,"lang":"en","type":"article","venue":"Pharmacogenomics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Pathogenesis; Gene; Biology; Computational biology; Candidate gene; Bioinformatics; Genetics; Immunology","score_opus":0.058546488405750094,"score_gpt":0.3222031114866521,"score_spread":0.263656623080902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059166555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962494,0.002681198,0.000068954876,0.00016555325,0.000069655056,0.00061093067,0.00008567155,0.000016614282,0.00005204273],"genre_scores_gemma":[0.99772274,0.0013146796,0.00026547574,0.0005258908,0.000030746927,0.00007779175,0.000003437857,0.000026698272,0.000032507138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874383,0.00015063497,0.0003217675,0.00036592418,0.00013448005,0.00028335024],"domain_scores_gemma":[0.99918044,0.00032248133,0.00019409232,0.00018548708,0.00006749157,0.000050001705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014284748,0.00023730233,0.00028536055,0.00013316296,0.0002256803,0.000056767556,0.00035754647,0.000040118062,0.000017102953],"category_scores_gemma":[0.00012225185,0.00016263714,0.000059718175,0.0002318469,0.0003830758,0.00023423664,0.00018276484,0.00013471344,0.0000036323622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023785711,0.00014372438,0.0060942792,0.000040859144,0.000030887775,0.000003846001,0.0044548064,0.00012886964,0.98694223,0.00020693791,0.00003062777,0.0018991451],"study_design_scores_gemma":[0.001857595,0.000039526847,0.00548112,0.000024102781,0.000047043864,0.0000072217613,0.00785289,0.00255677,0.98115283,0.0005980051,0.00010364534,0.00027922625],"about_ca_topic_score_codex":0.0007712517,"about_ca_topic_score_gemma":0.00036718723,"teacher_disagreement_score":0.0057893777,"about_ca_system_score_codex":0.000039591785,"about_ca_system_score_gemma":0.000030379542,"threshold_uncertainty_score":0.663215},"labels":[],"label_agreement":null},{"id":"W2059739275","doi":"10.1016/j.gene.2015.04.029","title":"Transcriptomic profiling of peripheral blood CD4+ T-cells in asthmatics with and without depression","year":2015,"lang":"en","type":"article","venue":"Gene","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"Transcriptome; Depression (economics); Asthma; Microarray; Biology; Gene expression profiling; Immunology; Pathophysiology; Microarray analysis techniques; Internal medicine; Gene; Gene expression; Endocrinology; Bioinformatics; Medicine; Genetics","score_opus":0.02673051618089305,"score_gpt":0.24630914381862098,"score_spread":0.21957862763772792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059739275","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99864316,0.00016028646,0.0004900571,0.000023039702,0.00004976682,0.00016663926,0.0000046072337,0.00001819589,0.00044426325],"genre_scores_gemma":[0.9944284,0.00001864652,0.00537494,0.00008403449,0.000010440107,0.0000055878904,6.2798614e-7,0.000011190047,0.00006611643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993835,0.00004241041,0.00012008063,0.00017775744,0.00014135151,0.00013491222],"domain_scores_gemma":[0.99976754,0.000012393806,0.00004038784,0.00010957144,0.000012268681,0.000057832367],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000075296106,0.000078667545,0.000118340926,0.00004235666,0.00001820189,0.000012559907,0.000080582686,0.000032297405,0.0000045732068],"category_scores_gemma":[0.000026009819,0.00006020375,0.000011648711,0.00011388713,0.000074175994,0.00006877515,0.000016021873,0.000064107386,0.0000011954501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007620837,0.00007289254,0.013721026,0.00002447951,0.0000015461185,0.0000039137026,0.00097331457,0.00019790544,0.98434544,0.000023729819,0.000008082891,0.00055144087],"study_design_scores_gemma":[0.0018803551,0.00011323298,0.0015358014,0.000028156554,0.000004504925,0.000017101975,0.00021386695,0.0012985804,0.9947002,0.000098458826,0.000027498463,0.00008223292],"about_ca_topic_score_codex":0.000010957067,"about_ca_topic_score_gemma":0.000023883274,"teacher_disagreement_score":0.012185224,"about_ca_system_score_codex":0.000006089665,"about_ca_system_score_gemma":0.00003994881,"threshold_uncertainty_score":0.24550377},"labels":[],"label_agreement":null},{"id":"W2060279710","doi":"10.1016/j.brainres.2014.06.002","title":"Unpredictable chronic mild stress induces anxiety and depression-like behaviors and inactivates AMP-activated protein kinase in mice","year":2014,"lang":"en","type":"article","venue":"Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":97,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Alberta; University of Saskatchewan; University of Manitoba","funders":"","keywords":"AMPK; Protein kinase A; Chronic stress; Endocrinology; Anxiety; Kinase; Tail suspension test; Internal medicine; Biology; Cell biology; Medicine; Behavioural despair test; Antidepressant; Hippocampus; Psychiatry","score_opus":0.050423206322653014,"score_gpt":0.3380387581955051,"score_spread":0.2876155518728521,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060279710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971365,0.0003737244,0.0000083003715,0.0007895188,0.000047635396,0.0008672028,0.00002001368,0.0000687359,0.00068838714],"genre_scores_gemma":[0.9987959,0.00013703718,0.00007304719,0.00013883889,0.000056336474,0.00017846808,0.0000067927513,0.00003473133,0.00057880103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966898,0.0008745305,0.00022482405,0.0008315003,0.0006072531,0.00077211484],"domain_scores_gemma":[0.9983435,0.00097301754,0.000056574176,0.00033385277,0.00005628595,0.00023676666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094929716,0.00021067502,0.00022140265,0.00039988785,0.00036198515,0.00018887292,0.00036618352,0.00018375227,0.00005821936],"category_scores_gemma":[0.0023050578,0.00018746678,0.000024035411,0.00092607574,0.00059427693,0.0003949047,0.0004309764,0.0007931377,0.000010749362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010132983,0.00017566867,0.007962535,0.0001067437,0.0000020854768,0.000009224154,0.00046643813,0.0000061496553,0.97868824,0.00011996491,0.00059249764,0.011769097],"study_design_scores_gemma":[0.0014010905,0.0001426386,0.039390694,0.00025726476,0.0000012762757,0.0000071279155,0.00043224933,0.00028419174,0.9540823,0.0003853995,0.0033780863,0.00023767524],"about_ca_topic_score_codex":0.0009675581,"about_ca_topic_score_gemma":0.00047461863,"teacher_disagreement_score":0.031428162,"about_ca_system_score_codex":0.00009412514,"about_ca_system_score_gemma":0.0001229106,"threshold_uncertainty_score":0.7644673},"labels":[],"label_agreement":null},{"id":"W2061226855","doi":"10.1371/journal.pone.0037747","title":"Mechanism Underlying Defective Interferon Gamma-Induced IDO Expression in Non-obese Diabetic Mouse Fibroblasts","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research","keywords":"Nod; NOD mice; STAT protein; Interferon; Immune system; Major histocompatibility complex; Interferon gamma; Biology; STAT1; Signal transduction; Immunology; Medicine; Endocrinology; Cell biology; STAT3; Diabetes mellitus","score_opus":0.08204947840947201,"score_gpt":0.2678181621541137,"score_spread":0.18576868374464167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061226855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978227,0.00003152378,0.00031218538,0.00007104538,0.00009363175,0.0004734555,0.000003921528,0.00010847545,0.0010830443],"genre_scores_gemma":[0.9989341,0.000017300248,0.00037959253,0.00024394259,0.000050724215,0.00007974944,0.0000015641956,0.000044947894,0.00024809572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982603,0.00017196912,0.00021759384,0.0004017865,0.0003491134,0.0005992046],"domain_scores_gemma":[0.99918425,0.00024155682,0.00008372956,0.0003073733,0.000018298355,0.00016477291],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014867459,0.0002107169,0.00024872104,0.00019775613,0.00009814252,0.000044894834,0.00025706622,0.0001193214,0.0001152724],"category_scores_gemma":[0.0003994343,0.00020127084,0.000055067445,0.00028722212,0.00004180128,0.00046941263,0.00017323863,0.00030758005,0.00027151668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046390385,0.0013296835,0.0005417387,0.000069986585,0.0000062147874,0.0000033757465,0.001823356,0.0000027542571,0.9956996,0.00020156588,0.000015407519,0.00025994075],"study_design_scores_gemma":[0.0006383026,0.0001807448,0.0034106395,0.00037294926,0.000008197961,0.0000010036825,0.00029183645,0.0003342522,0.99363273,0.00089130836,0.0000016226073,0.00023639639],"about_ca_topic_score_codex":0.000012004226,"about_ca_topic_score_gemma":0.000019996829,"teacher_disagreement_score":0.0028689008,"about_ca_system_score_codex":0.00010163322,"about_ca_system_score_gemma":0.000017347133,"threshold_uncertainty_score":0.82075864},"labels":[],"label_agreement":null},{"id":"W2061381094","doi":"10.1038/tp.2014.112","title":"Investigation of blood mRNA biomarkers for suicidality in an independent sample","year":2014,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of King's College; The King's University; University of Alberta","funders":"Lundbeckfonden; Canada Research Chairs; Government of Alberta; European Commission; National Institute for Health and Care Research; King's College London; South London and Maudsley NHS Foundation Trust","keywords":"Suicidal ideation; Antidepressant; Depression (economics); Schizophrenia (object-oriented programming); Internal medicine; Oncology; Medicine; Psychiatry; Clinical psychology; Psychology; Poison control; Anxiety; Suicide prevention","score_opus":0.04426702421206104,"score_gpt":0.2890894096804665,"score_spread":0.24482238546840546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061381094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916212,0.000030024768,0.0056913802,0.0016567367,0.00023385626,0.00030112232,0.0000955867,0.000030067526,0.00034004025],"genre_scores_gemma":[0.99162024,0.0000014226823,0.0077106715,0.00053377234,0.000057839625,0.00001713274,0.00004365908,0.000011399753,0.0000038562116],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989279,0.00011275385,0.00029517297,0.00028282925,0.00023094895,0.0001504078],"domain_scores_gemma":[0.99936885,0.00031462792,0.00008537106,0.0001469089,0.000023421086,0.000060848826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000291877,0.000094832976,0.00011290241,0.0001225754,0.000053143085,0.000013040683,0.00015649252,0.000069826805,0.00004156224],"category_scores_gemma":[0.000102556034,0.00009796763,0.0000650368,0.00023298517,0.000096899654,0.0001826984,0.0000041470994,0.00006796717,0.0000018851975],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027883405,0.00029601032,0.6470387,0.00013352321,0.000013146319,9.216073e-8,0.0005187204,0.0004231566,0.22317767,0.1260416,0.00007256688,0.0020059664],"study_design_scores_gemma":[0.002889318,0.00016360768,0.67503965,0.00002176931,0.000013990811,0.0000011899701,0.000055457163,0.0029764401,0.040906873,0.27766076,0.00008904081,0.00018191323],"about_ca_topic_score_codex":0.000060283826,"about_ca_topic_score_gemma":0.0006896036,"teacher_disagreement_score":0.1822708,"about_ca_system_score_codex":0.0000041405265,"about_ca_system_score_gemma":0.00008581914,"threshold_uncertainty_score":0.3995004},"labels":[],"label_agreement":null},{"id":"W2061967693","doi":"10.1016/j.jpsychires.2012.03.004","title":"Increase in dopaminergic, but not serotoninergic, receptors in T-cells as a marker for schizophrenia severity","year":2012,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Schizophrenia (object-oriented programming); Dopaminergic; Population; Serotonergic; Receptor; Serotonin; Psychology; Internal medicine; CD8; Dopamine; Psychosis; Endocrinology; Immune system; Medicine; Neuroscience; Immunology; Psychiatry","score_opus":0.049764146443797834,"score_gpt":0.3536756460087197,"score_spread":0.30391149956492186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061967693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99326235,0.0005811809,0.000020829411,0.0016354041,0.0010680216,0.0006513342,0.000009445064,0.000009974395,0.0027614767],"genre_scores_gemma":[0.9950721,0.0006836876,0.0020789187,0.0002888787,0.0006121516,0.000044163793,6.940289e-7,0.0000347827,0.0011845757],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99565965,0.0010055051,0.0008289865,0.000330111,0.0011607027,0.0010150475],"domain_scores_gemma":[0.9976014,0.0012490723,0.0002723395,0.0002910825,0.00017438302,0.0004117582],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004935423,0.00020441719,0.00038374032,0.0017519903,0.00013351046,0.000085399544,0.0007336412,0.00016499762,0.00029851196],"category_scores_gemma":[0.0023031558,0.00017009999,0.00019980299,0.0022154923,0.00014964097,0.00048512616,0.00012745924,0.001188574,0.00008419871],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.053957965,0.010269188,0.20197555,0.0008795793,0.00007038553,0.0004953108,0.0027899994,0.00040196403,0.53539914,0.010029181,0.13043883,0.053292893],"study_design_scores_gemma":[0.05515708,0.0049140723,0.42027515,0.00050078216,0.000048326296,0.0010466398,0.004292532,0.0020678516,0.34389102,0.01709409,0.14836669,0.0023457399],"about_ca_topic_score_codex":0.00030564348,"about_ca_topic_score_gemma":0.00008885656,"teacher_disagreement_score":0.21829961,"about_ca_system_score_codex":0.00019617862,"about_ca_system_score_gemma":0.00044730835,"threshold_uncertainty_score":0.6936476},"labels":[],"label_agreement":null},{"id":"W2062117677","doi":"10.1016/j.jaac.2013.11.013","title":"Inflammation in Children and Adolescents With Neuropsychiatric Disorders: A Systematic Review","year":2013,"lang":"en","type":"review","venue":"Journal of the American Academy of Child & Adolescent Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":244,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Bipolar disorder; Psychiatry; Clinical psychology; Major depressive disorder; Systematic review; Psychology; Population; Attention deficit hyperactivity disorder; Autism; Context (archaeology); Medicine; MEDLINE; Cognition","score_opus":0.011653150247076888,"score_gpt":0.2776769582096655,"score_spread":0.2660238079625886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062117677","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028805183,0.98863566,0.000008199819,0.004319629,0.0002467616,0.0038493725,0.000013790582,0.000017263534,0.000028825774],"genre_scores_gemma":[0.0059885373,0.9889668,0.00007238395,0.0045845467,0.00025981676,0.000026773358,6.3831277e-7,0.000091329544,0.000009144905],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.99394524,0.0014980806,0.0025921718,0.0005430085,0.0009720423,0.0004494559],"domain_scores_gemma":[0.99022585,0.00008736656,0.0089893155,0.00047463225,0.000033493205,0.00018936473],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005336489,0.00072813727,0.0035571358,0.000691872,0.000107941625,0.000054031254,0.001793648,0.00014986099,0.000004128894],"category_scores_gemma":[0.00031131678,0.00040562704,0.00090325606,0.002085549,0.0005253186,0.00030602165,0.00020352233,0.002281079,0.00000976593],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082131184,0.00067159574,0.005669392,0.90212137,0.0001745091,0.0000011150175,0.000029067633,0.0000059323647,0.000004623868,0.00010727119,0.001745845,0.08938714],"study_design_scores_gemma":[0.0009578044,0.00020922601,0.028857302,0.9614736,0.00166886,0.0010195873,0.000020198731,0.0000019724553,0.0000034256038,0.000091852424,0.0051422645,0.00055395206],"about_ca_topic_score_codex":0.0000038403855,"about_ca_topic_score_gemma":0.0000019454587,"teacher_disagreement_score":0.08883319,"about_ca_system_score_codex":0.00007216413,"about_ca_system_score_gemma":0.00022692216,"threshold_uncertainty_score":0.99983954},"labels":[],"label_agreement":null},{"id":"W2062748162","doi":"10.1016/j.euroneuro.2012.09.009","title":"Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response","year":2012,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Alberta","funders":"European Commission","keywords":"Escitalopram; Antidepressant; Cytokine; Tumor necrosis factor alpha; Medicine; Serotonin reuptake inhibitor; Major depressive disorder; Pharmacology; Oncology; Internal medicine; Immunology; Bioinformatics; Biology; Amygdala","score_opus":0.03244708624833665,"score_gpt":0.2982187449360101,"score_spread":0.26577165868767344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062748162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936721,0.00032441443,0.000023711864,0.0018266335,0.0016328903,0.0014495013,0.00018009458,0.0001913108,0.0006993584],"genre_scores_gemma":[0.98724574,0.000076932076,0.000018348393,0.012064862,0.00015421954,0.00011399059,0.000003570756,0.00012813442,0.00019421645],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9940063,0.0037083887,0.00048884976,0.0007267119,0.00024943182,0.00082033226],"domain_scores_gemma":[0.9976885,0.0015227428,0.00025393354,0.00026190976,0.0000412241,0.00023173823],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011022373,0.00038385848,0.00029261407,0.0003161455,0.00024188712,0.00010219633,0.00065490435,0.000053429816,0.000074706535],"category_scores_gemma":[0.0011711676,0.00031372145,0.00013591528,0.00047873455,0.0003085846,0.00044831156,0.0000891006,0.00040131778,0.00019376139],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003866473,0.000278471,0.00024094364,0.000040812312,0.000016645294,0.00031211885,0.0039719096,0.0000036953534,0.9882257,0.00015102596,0.0022645134,0.000627719],"study_design_scores_gemma":[0.009852777,0.00072160404,0.6031539,0.000031299838,0.00004015295,0.00028423715,0.0010127653,0.00018068944,0.31898737,0.00016641089,0.06473581,0.0008329675],"about_ca_topic_score_codex":0.0000018034282,"about_ca_topic_score_gemma":0.0000029597966,"teacher_disagreement_score":0.66923827,"about_ca_system_score_codex":0.00003441013,"about_ca_system_score_gemma":0.000042152835,"threshold_uncertainty_score":0.9999315},"labels":[],"label_agreement":null},{"id":"W2063144795","doi":"10.1038/sj.jid.5700022","title":"Local Expression of Indoleamine 2,3-Dioxygenase Protects Engraftment of Xenogeneic Skin Substitute","year":2005,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta; Sick Kids Foundation; Canadian Institutes of Health Research; Hospital for Sick Children; University of Miami","keywords":"Indoleamine 2,3-dioxygenase; Immune system; Immunology; Kynurenine; Transplantation; Cancer research; Angiogenesis; Wound healing; Biology; Medicine; Tryptophan","score_opus":0.027392813979613007,"score_gpt":0.26157718874832964,"score_spread":0.23418437476871662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063144795","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99675846,0.00041992834,0.0014879517,0.0008158907,0.00005889648,0.00023038713,0.000009855442,0.000009016655,0.0002095831],"genre_scores_gemma":[0.9967057,0.000055465927,0.0026205925,0.0005400927,0.000041571595,0.0000065577633,7.812287e-7,0.000013721192,0.0000154889],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979486,0.00039098022,0.00085668266,0.00018768906,0.0003722548,0.00024381297],"domain_scores_gemma":[0.9981091,0.0002376009,0.001108188,0.00018065471,0.00018988714,0.00017456792],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001714767,0.00018222124,0.00052247866,0.00030634916,0.000052925297,0.000005938294,0.00035172055,0.00012003909,0.000041093997],"category_scores_gemma":[0.00078414154,0.00014116852,0.00015120216,0.0003237183,0.001172274,0.00023695387,0.00007106935,0.00030039874,0.000008664516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013152238,0.0002428004,0.000011519558,0.000078817204,0.000015705462,0.000089073066,0.0009230008,0.00056359486,0.9953925,0.0010747451,0.00046410528,0.0010126338],"study_design_scores_gemma":[0.0014813137,0.00024396184,0.0012316837,0.00015166924,0.00000614006,0.0006291447,0.00024751207,0.00013256432,0.99378765,0.0009743989,0.0009973323,0.00011661543],"about_ca_topic_score_codex":0.000004258044,"about_ca_topic_score_gemma":0.000007949505,"teacher_disagreement_score":0.0016048184,"about_ca_system_score_codex":0.000043000055,"about_ca_system_score_gemma":0.00021956605,"threshold_uncertainty_score":0.5756685},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"agree"},{"id":"W2064995917","doi":"10.1055/s-0030-1251730","title":"Microarray Analysis as a Tool to Elucidate the Mechanism of Action of St. John's Wort","year":2010,"lang":"en","type":"article","venue":"Planta Medica","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Fluoxetine; Microarray; Microarray analysis techniques; DNA microarray; Hypericum perforatum; Gene; Gene expression; Depression (economics); Mechanism (biology); Mechanism of action; Medicine; Pharmacology; Hypericum; Biology; Bioinformatics; Genetics; Traditional medicine; Serotonin","score_opus":0.016985395299670622,"score_gpt":0.2672221392351664,"score_spread":0.2502367439354958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064995917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949358,0.0000053381013,0.000871744,0.001236024,0.00035131257,0.00017296938,0.00007681919,0.00002527073,0.0023247062],"genre_scores_gemma":[0.9984918,0.00004579721,0.00017867242,0.00093831803,0.000040382813,0.000009907611,0.000007903145,0.000007022849,0.0002801442],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988964,0.000056799192,0.00022223259,0.00023994416,0.00040929564,0.00017532097],"domain_scores_gemma":[0.9991837,0.00021524534,0.00013085206,0.00037095672,0.000021596732,0.000077612865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029422282,0.00009179766,0.00019496553,0.00017882734,0.00006277025,0.000012153486,0.00041469905,0.00006563567,0.00084665284],"category_scores_gemma":[0.00064130535,0.0000613642,0.00009537386,0.00066055974,0.00011322775,0.000054533357,0.00005962326,0.0001923195,0.00004259632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005425502,0.000052825544,0.000082589686,0.000010726534,0.000038864167,0.000005072621,0.000438496,0.000002129019,0.99196744,0.0020179187,0.0012773884,0.004052297],"study_design_scores_gemma":[0.00020944035,0.000054151125,0.0018543653,0.000009572476,0.000080792095,0.000013854109,0.00017793874,0.00011037361,0.98516303,0.00051628175,0.011726983,0.000083217135],"about_ca_topic_score_codex":0.0001292402,"about_ca_topic_score_gemma":0.00029404246,"teacher_disagreement_score":0.010449595,"about_ca_system_score_codex":0.000005058296,"about_ca_system_score_gemma":0.00005586187,"threshold_uncertainty_score":0.9270255},"labels":[],"label_agreement":null},{"id":"W2065948396","doi":"10.1016/j.biopsych.2008.08.009","title":"Risk for Depression During Interferon-Alpha Treatment Is Affected by the Serotonin Transporter Polymorphism","year":2008,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":135,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health","keywords":"Serotonin transporter; Internal medicine; Beck Depression Inventory; Major depressive disorder; Genotype; Depression (economics); Psychology; 5-HTTLPR; Neuroticism; Alpha interferon; Medicine; Psychiatry; Serotonin; Biology; Mood; Anxiety; Genetics; Interferon; Immunology; Personality; Gene","score_opus":0.035446953433111904,"score_gpt":0.2618591967763985,"score_spread":0.2264122433432866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065948396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958157,0.00075731555,0.0002811883,0.0012713127,0.00046187403,0.00081399095,0.00018323277,0.00015209672,0.0002632675],"genre_scores_gemma":[0.9971312,0.00042649315,0.00016383336,0.0014603675,0.00012922595,0.00018702343,0.000012766559,0.000016840067,0.000472202],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986379,0.00012870078,0.00021487148,0.0005530817,0.000105791594,0.00035962975],"domain_scores_gemma":[0.99939597,0.0001287174,0.00009735504,0.00028232622,0.0000075255143,0.00008808815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047628775,0.00023454081,0.00019210683,0.00002906081,0.00049945,0.000015812751,0.00029756775,0.000159027,0.00018722058],"category_scores_gemma":[0.000037009395,0.000118631826,0.00022463725,0.00012437318,0.00021607762,0.000049705777,0.000023117074,0.0001410104,0.000037131886],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023145543,0.002300624,0.17489061,0.000029535628,0.000064843865,0.000014200125,0.0011169721,0.0000050295184,0.790481,0.00020962188,0.019618794,0.008954252],"study_design_scores_gemma":[0.0052241352,0.0018824525,0.6567075,0.000030691906,0.00002586001,0.0000777898,0.00012174592,0.00007525356,0.32545325,0.0009085152,0.008975158,0.00051764253],"about_ca_topic_score_codex":0.00002363137,"about_ca_topic_score_gemma":0.000008010741,"teacher_disagreement_score":0.4818169,"about_ca_system_score_codex":0.000025915948,"about_ca_system_score_gemma":0.000020353624,"threshold_uncertainty_score":0.48376656},"labels":[],"label_agreement":null},{"id":"W2066725313","doi":"10.1016/j.eurpsy.2008.01.450","title":"A double-blind, placebo-controlled study with acute and continuation phase of Quetiapine and Lithium in adults with bipolar depression (Embolden I)","year":2008,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Mental Health & Substance Use Services; University of British Columbia","funders":"","keywords":"Quetiapine; Internal medicine; Morning; Bipolar disorder; Medicine; Depression (economics); Schizophrenia (object-oriented programming); Placebo; Psychosis; Psychopathology; Gastroenterology; Endocrinology; Lithium (medication); Psychiatry","score_opus":0.01857105718022026,"score_gpt":0.26996290919038585,"score_spread":0.25139185201016556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066725313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952546,0.0009156227,0.0000732325,0.00014883545,0.00006852382,0.0015893878,0.000006212296,0.000052889474,0.0018907295],"genre_scores_gemma":[0.9991488,0.00010160191,0.0003182575,0.00014487842,0.000043533288,0.0000266345,0.0000030314206,0.000038205933,0.00017507143],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99832535,0.00034813676,0.0003269694,0.0005259968,0.00026745876,0.00020610148],"domain_scores_gemma":[0.99932265,0.00006353947,0.00021982033,0.0002644089,0.00003380666,0.000095758835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025390004,0.00021801535,0.00032853094,0.00020197262,0.00012278653,0.00003102342,0.00014881352,0.000029957513,0.000007878578],"category_scores_gemma":[0.000033243712,0.00014909438,0.000024079534,0.00032752263,0.00018317642,0.00020850768,0.000056293393,0.000185423,0.000003915063],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.6095596,0.0051682307,0.33420813,0.00015151071,0.00014785427,0.0005200564,0.021561276,0.000032502423,0.024217838,0.00024683762,0.00036413534,0.0038219984],"study_design_scores_gemma":[0.8526258,0.0071159373,0.12813714,0.0007856168,0.00013048975,0.00038885552,0.0032532949,0.0003669127,0.006257372,0.000029641664,0.00022660987,0.00068233354],"about_ca_topic_score_codex":0.00002656212,"about_ca_topic_score_gemma":0.0001910208,"teacher_disagreement_score":0.24306618,"about_ca_system_score_codex":0.0000051788184,"about_ca_system_score_gemma":0.000051508126,"threshold_uncertainty_score":0.6079892},"labels":[],"label_agreement":null},{"id":"W2066738717","doi":"10.1177/0269881112444941","title":"Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment","year":2012,"lang":"en","type":"article","venue":"Journal of Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":285,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Janssen Pharmaceuticals; National Institute for Health and Care Research; Stanley Medical Research Institute; Eli Lilly and Company","keywords":"Minocycline; Apathy; Placebo; Schizophrenia (object-oriented programming); Antipsychotic; Psychosis; Positive and Negative Syndrome Scale; Medicine; Internal medicine; Randomized controlled trial; Psychiatry; Population; Psychology; Antibiotics; Cognition","score_opus":0.06608662485706934,"score_gpt":0.3859502058608767,"score_spread":0.31986358100380735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066738717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99080527,0.00018147031,0.0000036506835,0.00041742733,0.005117154,0.0030030226,0.000015325693,0.000011444765,0.00044524448],"genre_scores_gemma":[0.9977798,0.00029466595,0.00006581744,0.00073280337,0.00091760984,0.0001302806,9.85303e-7,0.000026384752,0.000051677027],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99536586,0.0013031757,0.0019072881,0.0003597461,0.00046472048,0.0005991819],"domain_scores_gemma":[0.99588543,0.0024843495,0.0010576622,0.00015742677,0.00008439406,0.00033075517],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013769369,0.00032719402,0.0012876103,0.000710251,0.000060450326,0.000032338718,0.00033085782,0.0002438245,0.00013799936],"category_scores_gemma":[0.00073929055,0.00023764069,0.00047522664,0.0004111376,0.00014482216,0.00031397698,0.000027761856,0.0007361337,0.000029701761],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9755654,0.0056518693,0.0101171145,0.0000028778452,0.00011524414,0.000029074521,0.00053817715,0.0001227404,0.00071726966,0.00004067834,0.0003006421,0.006798957],"study_design_scores_gemma":[0.958789,0.010504412,0.026872242,0.000034986097,0.00007937209,0.0000055836626,0.000024587855,0.000021805785,0.0031844794,0.00008141999,0.00020889357,0.00019323525],"about_ca_topic_score_codex":0.000008624265,"about_ca_topic_score_gemma":0.00003380524,"teacher_disagreement_score":0.016776374,"about_ca_system_score_codex":0.00021089673,"about_ca_system_score_gemma":0.00017018421,"threshold_uncertainty_score":0.9690706},"labels":[],"label_agreement":null},{"id":"W2066901708","doi":"10.1016/j.phrs.2010.10.009","title":"Effects of PEG-interferon alpha plus ribavirin on tryptophan metabolism in patients with chronic hepatitis C","year":2010,"lang":"en","type":"article","venue":"Pharmacological Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Regione del Veneto","keywords":"Ribavirin; Kynurenine; Medicine; Internal medicine; Alpha interferon; Hepatitis C; Gastroenterology; Alpha (finance); Pegylated interferon; PEG ratio; Pharmacology; Tryptophan; Hepatitis C virus; Immunology; Endocrinology; Interferon; Chemistry; Biochemistry; Virus; Surgery","score_opus":0.0390471601954913,"score_gpt":0.35628719318516255,"score_spread":0.31724003298967124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066901708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964029,0.000060739465,0.000008175954,0.000248005,0.00029833554,0.0012071826,0.000012491058,0.00004651892,0.0017156389],"genre_scores_gemma":[0.9990624,0.00012442522,0.000030699735,0.00028923422,0.00009244702,0.00018677629,0.0000027161,0.00002345389,0.00018780123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964526,0.0007231167,0.00026618972,0.00063676736,0.0011098671,0.00081143645],"domain_scores_gemma":[0.9975406,0.0018373271,0.00006607685,0.00022245607,0.00010637792,0.00022716263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051396515,0.00020971433,0.00032901208,0.0003318405,0.00012877095,0.000041645624,0.00070027594,0.00013224235,0.0007928542],"category_scores_gemma":[0.0013410037,0.00014555102,0.00006897315,0.0008168627,0.0006269212,0.0001490174,0.00024329513,0.0014766827,0.00014924812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022425496,0.0017459925,0.0045844205,0.00009008477,0.000011507962,0.000087765016,0.00012020349,0.000023091454,0.974764,0.0018430913,0.00054994115,0.013937373],"study_design_scores_gemma":[0.0052571236,0.0018559375,0.31658962,0.000027944094,0.000004768932,5.4992887e-7,0.0000029205332,0.00020768758,0.67457306,0.000278965,0.00105661,0.00014482904],"about_ca_topic_score_codex":0.00012172568,"about_ca_topic_score_gemma":0.00012633367,"teacher_disagreement_score":0.3120052,"about_ca_system_score_codex":0.00013597446,"about_ca_system_score_gemma":0.00013994069,"threshold_uncertainty_score":0.8681197},"labels":[],"label_agreement":null},{"id":"W2067871560","doi":"10.1016/j.neulet.2015.02.028","title":"Effects of haloperidol and clozapine administration on oxidative stress in rat brain, liver and serum","year":2015,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Haloperidol; Lipid peroxidation; Oxidative stress; Clozapine; Internal medicine; Pharmacology; Endocrinology; Medicine; Schizophrenia (object-oriented programming); Dopamine; Psychiatry","score_opus":0.025485317738117165,"score_gpt":0.2588871292186589,"score_spread":0.23340181148054176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067871560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99337065,0.000030385456,0.000056437475,0.005896828,0.0002505458,0.0002965681,0.000006392622,0.000022294906,0.00006989694],"genre_scores_gemma":[0.97982526,0.000050305316,0.000029966177,0.020019185,0.00001723868,0.000009573344,3.3372453e-7,0.000008236348,0.000039873434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869233,0.00016837739,0.00014296405,0.0004810899,0.00028894487,0.00022629304],"domain_scores_gemma":[0.99936056,0.00030956397,0.00007306568,0.00012918898,0.000011318407,0.000116288546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118033815,0.00013611862,0.0001369314,0.00013268187,0.000058801616,0.000060468992,0.00016758361,0.000033617285,0.0000014054168],"category_scores_gemma":[0.0011395711,0.0001209041,0.000015028209,0.00034380943,0.00052653585,0.00033336942,0.000067276385,0.00013147494,0.0000022984252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066299406,0.00008159242,0.0018076805,0.000038503535,1.8121729e-7,0.00008317809,0.0005925244,0.00003655622,0.9946073,0.0002519477,0.00044763935,0.0019865665],"study_design_scores_gemma":[0.00093417795,0.0005057829,0.038777065,0.000040831485,0.0000013933516,0.000016144524,0.00006112718,0.00053808454,0.95841974,0.000030799227,0.0005465176,0.0001283605],"about_ca_topic_score_codex":0.000012547894,"about_ca_topic_score_gemma":0.000013366235,"teacher_disagreement_score":0.036969386,"about_ca_system_score_codex":0.000014401188,"about_ca_system_score_gemma":0.000031007465,"threshold_uncertainty_score":0.4930326},"labels":[],"label_agreement":null},{"id":"W2068583943","doi":"10.1186/1710-1492-6-s3-p8","title":"Respiratory syncytial virus replication induces Indoleamine 2,3-dioxygenase (IDO) activation in human dendritic cells","year":2010,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Bronchiolitis; Immunology; Biology; Virus; Flow cytometry; Virology","score_opus":0.03754342404088807,"score_gpt":0.32877875001595386,"score_spread":0.2912353259750658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068583943","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980125,0.000051538736,0.000030444084,0.00032988697,0.00049210363,0.0001865856,0.0000027376964,0.0000674641,0.0008267532],"genre_scores_gemma":[0.9979254,0.00014917998,0.000039522958,0.001540954,0.00015810638,0.000030156418,0.0000068091795,0.000020296837,0.00012959917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99776375,0.00039107382,0.00064532016,0.0007519226,0.00012443218,0.00032350037],"domain_scores_gemma":[0.99846184,0.0006560503,0.00019967947,0.0005672051,0.000034075172,0.00008116055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043206167,0.00017753041,0.0002813775,0.00016145394,0.00016956664,0.000036335583,0.00031951553,0.0004531171,0.0001696834],"category_scores_gemma":[0.0012938823,0.00017537107,0.000073942814,0.00022997442,0.000574586,0.00021702118,0.00013653057,0.0009064831,0.000057533936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000106583044,0.00037462512,0.00013485638,0.0000030903232,0.00001309459,0.000008279088,0.00006569876,9.3204113e-7,0.97880435,0.00445035,0.00007311897,0.015965046],"study_design_scores_gemma":[0.0017331844,0.00043905393,0.16238691,0.00001335734,0.0000012572607,0.0000066993625,0.000077779325,0.000023934583,0.8239214,0.001142576,0.010037876,0.00021598767],"about_ca_topic_score_codex":0.0001096941,"about_ca_topic_score_gemma":0.0006304503,"teacher_disagreement_score":0.16225205,"about_ca_system_score_codex":0.000015379712,"about_ca_system_score_gemma":0.000057787776,"threshold_uncertainty_score":0.7151425},"labels":[],"label_agreement":null},{"id":"W2069270603","doi":"10.1007/s00277-012-1451-0","title":"Decreased indoleamine 2,3-dioxygenase expression in dendritic cells and role of indoleamine 2,3-dioxygenase-expressing dendritic cells in immune thrombocytopenia","year":2012,"lang":"en","type":"article","venue":"Annals of Hematology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; St. Michael's Hospital","funders":"National Science Foundation","keywords":"Indoleamine 2,3-dioxygenase; Immune system; Flow cytometry; Immunology; Immune tolerance; Dendritic cell; Kynurenine; Mixed lymphocyte reaction; CTLA-4; Cancer research; Medicine; Biology; T cell","score_opus":0.03411859100454438,"score_gpt":0.29070048051653036,"score_spread":0.25658188951198596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069270603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925474,0.0062722787,0.000028920535,0.00008392972,0.00012433251,0.0004431422,0.00004039339,0.000029973204,0.00042962917],"genre_scores_gemma":[0.9986279,0.00047874163,0.00044555773,0.0003177727,0.000025387775,0.000033103774,0.000007535266,0.000044923163,0.000019085595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996554,0.0005522336,0.0010793401,0.00055526674,0.00032025314,0.0009389114],"domain_scores_gemma":[0.99792665,0.00088069757,0.00039365268,0.0005145093,0.00005216134,0.00023230606],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042660628,0.0003673803,0.0011381705,0.00062952365,0.00006731536,0.00001950823,0.00044013024,0.0002860857,0.00008980992],"category_scores_gemma":[0.0005682549,0.00035939924,0.00012316898,0.00055974146,0.00045901517,0.00047478706,0.0002654204,0.00034540662,0.000016781596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020398229,0.0009777335,0.002411391,0.00031036284,0.000006670967,0.00006734687,0.0009391562,0.000020035968,0.99397415,0.00047628992,0.00006899891,0.00054385304],"study_design_scores_gemma":[0.0019748516,0.00013255764,0.01775553,0.0005008226,0.000003107451,0.000092457,0.0008777161,0.0001111469,0.9776463,0.0005126764,0.000077662604,0.0003151898],"about_ca_topic_score_codex":0.000112270085,"about_ca_topic_score_gemma":0.00005788058,"teacher_disagreement_score":0.016327897,"about_ca_system_score_codex":0.000013832686,"about_ca_system_score_gemma":0.000071371025,"threshold_uncertainty_score":0.9998858},"labels":[],"label_agreement":null},{"id":"W2069294598","doi":"10.1016/j.mehy.2007.01.078","title":"Thiazolidinediones: From antioxidant to neurotherapeutic?","year":2007,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Neurocognitive; Allostasis; Mood; Neuroscience; Mood disorders; Psychology; Disease; Neuroplasticity; Medicine; Cognition; Psychiatry; Internal medicine; Anxiety","score_opus":0.04604333677956854,"score_gpt":0.3003485550567019,"score_spread":0.25430521827713337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069294598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9785001,0.00010135007,0.0063851103,0.0048561394,0.0005688282,0.00020571842,0.000011341054,0.00023944165,0.009131916],"genre_scores_gemma":[0.9686408,0.000065767774,0.00030888306,0.030246565,0.00034951878,0.0000073597075,4.998809e-7,0.000028478962,0.00035213222],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99792117,0.00007937385,0.00025681686,0.00043432842,0.00086137874,0.00044693495],"domain_scores_gemma":[0.9977321,0.0014903612,0.000036538775,0.00028139175,0.000014841191,0.0004447611],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00032770823,0.00015654886,0.0001783674,0.000110178975,0.000104551706,0.00004013392,0.0005028445,0.00010411029,0.0019741917],"category_scores_gemma":[0.003621368,0.00012112047,0.00007205311,0.00038087388,0.00017243924,0.000075439966,0.000084710366,0.00019874163,0.0008868836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019263572,0.00039175403,0.0011004066,0.000010316261,0.000009222642,0.00039939882,0.0007627402,0.0000020076957,0.826996,0.0054593943,0.00314716,0.16152896],"study_design_scores_gemma":[0.00082198816,0.00018186618,0.034924544,0.0000720512,0.000005843621,0.00003259061,0.00026284286,0.00008583447,0.7569672,0.0048068226,0.20147151,0.0003669135],"about_ca_topic_score_codex":0.000057807407,"about_ca_topic_score_gemma":0.000054965356,"teacher_disagreement_score":0.19832435,"about_ca_system_score_codex":0.000014752549,"about_ca_system_score_gemma":0.000050210056,"threshold_uncertainty_score":0.99989104},"labels":[],"label_agreement":null},{"id":"W2069486241","doi":"10.1016/j.psym.2011.10.001","title":"A Genetic Predisposition to Produce Low Levels of IL-10 is Related to Depressive Symptoms: A Pilot Study of Patients with End Stage Renal Disease","year":2012,"lang":"en","type":"article","venue":"Psychosomatics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"University of Toronto","keywords":"Medicine; Depression (economics); Disease; End stage renal disease; Cytokine; Beck Depression Inventory; Internal medicine; Single-nucleotide polymorphism; Kidney disease; Immunology; Genotype; Psychiatry; Anxiety; Gene; Biology; Genetics","score_opus":0.020575982739442895,"score_gpt":0.26857677671272717,"score_spread":0.24800079397328428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069486241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99683636,0.00001678556,0.000307681,0.000057178393,0.00011712615,0.0020753827,0.00046270015,0.000036017234,0.000090772686],"genre_scores_gemma":[0.99899065,0.0000010132605,0.0004830795,0.0002075803,0.000017272501,0.00009579131,0.000003681823,0.000031715186,0.00016920545],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99816984,0.00012046461,0.00042213258,0.00037094683,0.000611529,0.0003051048],"domain_scores_gemma":[0.9986936,0.000082643055,0.0002475223,0.0005729483,0.00010970688,0.00029359857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000060511902,0.000191279,0.00022069596,0.0001482255,0.000058355632,0.000017024433,0.0002732156,0.00002429753,0.00014646746],"category_scores_gemma":[0.00024956092,0.00015932716,0.00002877707,0.00055615924,0.00006112893,0.00015857317,0.000068988666,0.00007040745,0.000028238068],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033291897,0.03096652,0.7668531,0.00069465727,0.00014948336,0.000008323285,0.044622574,0.0010942699,0.14795154,0.000096910764,0.0009158672,0.0033175924],"study_design_scores_gemma":[0.0018714708,0.0034208735,0.96741956,0.00019439701,0.000045541303,4.0625537e-7,0.00016580638,0.000095626085,0.026498102,0.000056894874,0.000022600101,0.0002086892],"about_ca_topic_score_codex":0.0000057029733,"about_ca_topic_score_gemma":0.0000041512353,"teacher_disagreement_score":0.20056652,"about_ca_system_score_codex":0.00002233125,"about_ca_system_score_gemma":0.000029768813,"threshold_uncertainty_score":0.64971733},"labels":[],"label_agreement":null},{"id":"W2069678140","doi":"10.1186/1710-1492-6-s2-p24","title":"Expression and roles of glutamate (NMDA) receptors on T cell subsets","year":2010,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Manitoba","funders":"","keywords":"NMDA receptor; Excitotoxicity; Glutamate receptor; Catabolism; Immune system; Receptor; Cell biology; Biology; Quinolinic acid; Indoleamine 2,3-dioxygenase; Tryptophan; Chemistry; Biochemistry; Amino acid; Immunology; Enzyme","score_opus":0.017106342582326142,"score_gpt":0.28344310075073675,"score_spread":0.2663367581684106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069678140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995887,0.00020858599,0.000008281086,0.00041750193,0.00069025636,0.00007576362,0.0000035742464,0.00003590447,0.002673141],"genre_scores_gemma":[0.9969073,0.0021483982,0.00011848814,0.00044570008,0.000038614962,0.0000042673246,0.0000017927538,0.000013445514,0.00032198962],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868214,0.00020353011,0.00036487376,0.00042426775,0.00009533046,0.00022984165],"domain_scores_gemma":[0.99868184,0.00080449827,0.00015381651,0.0002621728,0.000017997943,0.00007966743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017312873,0.00014247997,0.0002626746,0.000057178364,0.00009922823,0.000014791449,0.00019485553,0.00029395308,0.00023684016],"category_scores_gemma":[0.00044934207,0.000114603834,0.000067656416,0.0000709669,0.0008171387,0.00006942906,0.00015236856,0.0004553026,0.00003670064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003494729,0.0003383044,0.0008339889,0.000005979998,0.00001318534,0.0000049280334,0.00012602228,5.934956e-7,0.9579382,0.003722168,0.00029158173,0.0363756],"study_design_scores_gemma":[0.0028303051,0.0013647933,0.07778171,0.000034569475,0.0000034068676,0.00001857175,0.0002493365,0.000051520954,0.85050887,0.0024165078,0.064440854,0.0002995399],"about_ca_topic_score_codex":0.0000071408344,"about_ca_topic_score_gemma":0.0000453122,"teacher_disagreement_score":0.10742928,"about_ca_system_score_codex":0.0000015356628,"about_ca_system_score_gemma":0.000017266151,"threshold_uncertainty_score":0.46734086},"labels":[],"label_agreement":null},{"id":"W2069793088","doi":"10.1016/j.bbrc.2004.03.137","title":"Inhibition of human P450 enzymes by nicotinic acid and nicotinamide","year":2004,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Nicotinamide; Nicotinic agonist; Enzyme; Chemistry; Biochemistry; Pharmacology; Biology","score_opus":0.07848296052862996,"score_gpt":0.3669556221577739,"score_spread":0.2884726616291439,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069793088","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935271,0.00097009307,0.000012570361,0.003932296,0.0000045451,0.00018691827,0.000042615025,0.00003412794,0.001289708],"genre_scores_gemma":[0.99849534,0.0010314015,0.00019876559,0.00012585614,0.000018046827,0.000027395577,0.00002585819,0.000009542052,0.00006777106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987096,0.00017959779,0.00020597348,0.00030664753,0.00032533106,0.0002728087],"domain_scores_gemma":[0.99867266,0.00046154,0.00004673431,0.0005855765,0.000073795396,0.00015968524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019954816,0.00010383945,0.00014893246,0.00007495526,0.000361711,0.00004787834,0.00043133213,0.00008326201,0.00000970838],"category_scores_gemma":[0.00069688645,0.00008929015,0.0000453709,0.00042657694,0.0023525623,0.00009615213,0.0005734571,0.00039452268,0.000012537405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012497529,0.00044449515,0.000014043247,0.000025000652,0.0000023300042,2.4030876e-7,0.0000934259,1.8894625e-8,0.9489692,0.049070377,0.000571855,0.0007965293],"study_design_scores_gemma":[0.0004818867,0.0001763288,0.00046899248,0.0000498017,0.0000027631052,0.0000019628737,0.000109659406,0.000017037963,0.98100954,0.017132541,0.00045227524,0.00009722498],"about_ca_topic_score_codex":0.000070415925,"about_ca_topic_score_gemma":0.0000064970195,"teacher_disagreement_score":0.03204034,"about_ca_system_score_codex":0.000025027231,"about_ca_system_score_gemma":0.00003830061,"threshold_uncertainty_score":0.86681134},"labels":[],"label_agreement":null},{"id":"W2070029808","doi":"10.1016/j.jneuroim.2014.09.019","title":"Family-based association study of interleukin 6 (IL6) and its receptor (IL6R) functional polymorphisms in schizophrenia in the Polish population","year":2014,"lang":"en","type":"article","venue":"Journal of Neuroimmunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia (object-oriented programming); Pathogenesis; Haplotype; Genotyping; SNP; Psychosis; Medicine; Single-nucleotide polymorphism; Immunology; Biology; Gene; Genetics; Genotype; Psychiatry","score_opus":0.02792040506229602,"score_gpt":0.24988691464241544,"score_spread":0.22196650958011943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070029808","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99801373,0.00007709338,0.000010142288,0.001164975,0.000504188,0.00016544812,0.0000021985632,0.000005840731,0.00005640564],"genre_scores_gemma":[0.9991927,0.000021443833,0.000013237186,0.0006914365,0.00005220259,0.0000034580298,9.627736e-7,0.000009172647,0.000015377187],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99776435,0.001034455,0.00055955164,0.00016670473,0.00030458023,0.0001703338],"domain_scores_gemma":[0.99849844,0.0007229948,0.0005887173,0.00011745385,0.000053652937,0.000018725694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062837725,0.00010646596,0.0002549184,0.00046645218,0.00004765362,0.000024683892,0.00024828353,0.00008450687,0.000015266041],"category_scores_gemma":[0.0015231824,0.000082750696,0.00004927368,0.0004029911,0.00003570803,0.00018902175,0.000034150693,0.00044169606,0.0000030167453],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012381664,0.0010988192,0.12637268,0.000008250575,0.0000114043505,0.000015442949,0.0010879667,0.00039314764,0.8655493,0.00079599774,0.00016326236,0.0032655185],"study_design_scores_gemma":[0.003446744,0.0010230934,0.9931535,0.000020284602,0.0000059131253,0.00001940639,0.00030355327,0.00028217857,0.0012559615,0.00031795487,0.000105635234,0.00006575339],"about_ca_topic_score_codex":0.0000702325,"about_ca_topic_score_gemma":0.00007999353,"teacher_disagreement_score":0.8667808,"about_ca_system_score_codex":0.0000710715,"about_ca_system_score_gemma":0.000035674657,"threshold_uncertainty_score":0.33744755},"labels":[],"label_agreement":null},{"id":"W2070477028","doi":"10.1016/s0306-9877(03)00319-0","title":"Schizophrenia and cancer: the adrenochrome balanced morphism","year":2003,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Adrenochrome; Population; Cancer; Schizophrenia (object-oriented programming); Medicine; Incidence (geometry); Psychiatry; Internal medicine; Environmental health; Epinephrine","score_opus":0.029752867060089633,"score_gpt":0.26608678393447543,"score_spread":0.2363339168743858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070477028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9347013,0.0025239424,0.000120414654,0.005496549,0.00031699514,0.00023242373,0.000008146371,0.00016646381,0.05643375],"genre_scores_gemma":[0.992686,0.00082368683,0.000068745896,0.0038646788,0.00006281442,0.000028477063,9.8097495e-8,0.000022310865,0.002443186],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99888504,0.00013521932,0.00010721483,0.00025475802,0.00037824217,0.00023955847],"domain_scores_gemma":[0.9991225,0.00050362915,0.000031931148,0.00017970166,0.0000054053403,0.00015683478],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014113242,0.00010701207,0.00011960504,0.000030800395,0.00013791055,0.000031627154,0.00023836271,0.0000606626,0.004666963],"category_scores_gemma":[0.0029853177,0.00006313781,0.000029274628,0.00017509982,0.0005164854,0.000041339044,0.00003814484,0.00015777824,0.00011236756],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015815053,0.00045287382,0.0033548805,0.00008753852,0.000045096276,0.0002883687,0.0011023536,0.0000066079,0.18969162,0.26483414,0.03191686,0.5080615],"study_design_scores_gemma":[0.0040214527,0.00016478251,0.027394632,0.00019114709,0.000022017235,0.0003116984,0.00025928894,0.000387772,0.21215522,0.026301393,0.7280575,0.0007330713],"about_ca_topic_score_codex":0.000019871723,"about_ca_topic_score_gemma":0.000024113318,"teacher_disagreement_score":0.69614065,"about_ca_system_score_codex":0.0000075236376,"about_ca_system_score_gemma":0.000069303795,"threshold_uncertainty_score":0.9962429},"labels":[],"label_agreement":null},{"id":"W2070757879","doi":"10.3389/fncel.2013.00218","title":"Neuroplasticity and the next wave of antidepressant strategies","year":2013,"lang":"en","type":"review","venue":"Frontiers in Cellular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Neuroplasticity; Neurogenesis; Antidepressant; Neuroscience; Synaptogenesis; Psychology; Neurotrophic factors; Depression (economics); Medicine; Hippocampus; Internal medicine; Receptor","score_opus":0.07769099976394668,"score_gpt":0.27862741287842746,"score_spread":0.2009364131144808,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070757879","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009116903,0.99049985,0.003613927,0.000030791467,0.002302201,0.0014904287,0.000025917532,0.000046501085,0.001078684],"genre_scores_gemma":[0.005569346,0.99363154,0.0002566756,0.00017459442,0.000035189485,0.00006307839,0.0000011628473,0.000045257246,0.00022314559],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99598336,0.0009675945,0.0007844357,0.0011252143,0.00056006707,0.0005793092],"domain_scores_gemma":[0.99786526,0.00077747914,0.0005190951,0.00070161786,0.000022593827,0.0001139475],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.00039427867,0.0005116301,0.0014689562,0.00035457773,0.000188224,0.00036004256,0.0012401488,0.00017010064,0.000011487751],"category_scores_gemma":[0.0013498075,0.0003198672,0.00027711646,0.0011695904,0.0035223623,0.0005163836,0.00046335752,0.000714557,0.0000066998523],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007616986,0.00033059026,0.0000419752,0.011920203,0.000012605575,0.00045070972,0.0006299846,0.000112380134,0.010821808,0.01412622,0.002565783,0.9589116],"study_design_scores_gemma":[0.0022790313,0.00023665502,0.000110932146,0.0039338027,0.00023227262,0.00027136024,0.0005009447,0.014766273,0.004312362,0.0069838497,0.9647099,0.0016626333],"about_ca_topic_score_codex":0.000029389832,"about_ca_topic_score_gemma":0.0000012258818,"teacher_disagreement_score":0.9621441,"about_ca_system_score_codex":0.00002124352,"about_ca_system_score_gemma":0.00022864381,"threshold_uncertainty_score":0.9999253},"labels":[],"label_agreement":null},{"id":"W2070772124","doi":"10.1055/s-2006-941557","title":"The Comparison of Changes in Behavior, Neurochemistry, Endocrine, and Immune Functions after Different Routes, Doses and Durations of Administrations of IL-1β in Rats","year":2006,"lang":"en","type":"article","venue":"Pharmacopsychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"","keywords":"Corticosterone; Internal medicine; Endocrinology; Elevated plus maze; Monoamine neurotransmitter; Dopamine; Anxiogenic; Open field; Serotonin; Neurotransmitter; Medicine; Immune system; Cytokine; Hormone; Anxiolytic; Central nervous system; Immunology; Anxiety","score_opus":0.017485193010913645,"score_gpt":0.2984021928947804,"score_spread":0.28091699988386676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070772124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99690133,0.0015424269,0.00000739599,0.00075569877,0.00016481975,0.00024053334,0.000115821735,0.000008513429,0.00026346894],"genre_scores_gemma":[0.9994865,0.00027249957,0.000029889214,0.000026431528,0.000021087231,0.000083314364,0.000007086946,0.0000074816803,0.0000656746],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991083,0.00006020292,0.00039089803,0.00018387381,0.00011936654,0.00013731774],"domain_scores_gemma":[0.99949646,0.00016711843,0.0001544557,0.00013488425,0.000019220346,0.000027860844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003726017,0.00011174036,0.0001788784,0.00008679491,0.00006400941,0.000014512572,0.000098884775,0.000024528426,0.000021053836],"category_scores_gemma":[0.000029536857,0.00009177877,0.000031019426,0.00022896094,0.00021967122,0.000058561065,0.000041963845,0.00012296539,1.94609e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008514876,0.0006368559,0.18677942,0.00006104501,0.0000022568506,9.994051e-7,0.00013354335,0.000009111278,0.81127065,0.0002540325,0.000093730705,0.0006731776],"study_design_scores_gemma":[0.0006549661,0.000053807624,0.5423103,0.000021019709,0.000015305428,0.0000040689115,0.00029860297,0.00011845037,0.45628685,0.00009236073,0.00008050923,0.000063774736],"about_ca_topic_score_codex":0.00009956728,"about_ca_topic_score_gemma":0.0019155247,"teacher_disagreement_score":0.35553086,"about_ca_system_score_codex":0.000005609956,"about_ca_system_score_gemma":0.000031563104,"threshold_uncertainty_score":0.37426296},"labels":[],"label_agreement":null},{"id":"W2070879379","doi":"10.1016/j.bbi.2013.07.177","title":"C-reactive protein predicts fatigue independently of depression in breast cancer patients prior to chemotherapy","year":2013,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":95,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"Irish Research Council","keywords":"Depression (economics); Kynurenine; Breast cancer; Inflammation; Internal medicine; Medicine; Oncology; Cancer; Cancer-related fatigue; Chemotherapy; Cytokine; Kynurenine pathway; Pathogenesis; Tumor necrosis factor alpha; Immunology; Biology; Tryptophan","score_opus":0.019656299134804316,"score_gpt":0.27963023529815956,"score_spread":0.25997393616335523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070879379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997725,0.000012687839,0.000007230158,0.0003208333,0.00005112999,0.0016244709,0.000055630786,0.000025961384,0.00017707236],"genre_scores_gemma":[0.99892825,0.0000066454204,0.000035484813,0.00045758524,0.000007812737,0.00042576512,0.0000043195473,0.000018226498,0.00011594119],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988434,0.00015342026,0.00023259877,0.00028411445,0.00024420206,0.00024227035],"domain_scores_gemma":[0.9994281,0.00006955491,0.0001013885,0.00023316307,0.00006126654,0.00010650476],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008989348,0.0001577231,0.00018438272,0.0001333315,0.00009299732,0.000033294054,0.00023908938,0.00009254039,0.00024141524],"category_scores_gemma":[0.00012619408,0.00013661174,0.000033776938,0.00026670157,0.00009843061,0.000315902,0.00011766247,0.00022070462,0.000007637528],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008734306,0.0006863834,0.33103448,0.000014341458,0.0000013720787,7.2723657e-7,0.0011064226,7.53857e-7,0.62432635,0.000004776155,0.00007947965,0.042657543],"study_design_scores_gemma":[0.0012296789,0.00007224713,0.73841023,0.00007258228,0.000001984392,0.0000012928904,0.00013904473,0.0000063924695,0.25991306,0.000024161345,0.000017683959,0.00011163623],"about_ca_topic_score_codex":0.0024834436,"about_ca_topic_score_gemma":0.000072521536,"teacher_disagreement_score":0.40737575,"about_ca_system_score_codex":0.00004012819,"about_ca_system_score_gemma":0.00003850239,"threshold_uncertainty_score":0.55708647},"labels":[],"label_agreement":null},{"id":"W2071238162","doi":"10.1016/j.bbi.2009.07.001","title":"Cytokine-induced depression during IFN-α treatment: The role of IL-6 and sleep quality","year":2009,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":140,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health","keywords":"Depression (economics); Beck Depression Inventory; Inflammation; Major depressive disorder; Internal medicine; Cohort; Cytokine; Systemic inflammation; Alpha interferon; Medicine; Sleep (system call); Depressive symptoms; Incidence (geometry); Clinical psychology; Psychology; Psychiatry; Immunology; Interferon; Cognition; Anxiety; Amygdala","score_opus":0.031680211884835476,"score_gpt":0.301300613394407,"score_spread":0.2696204015095715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071238162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99837416,0.00030840104,0.0000014987066,0.00019662331,0.000028896375,0.0002706049,0.000026116799,0.000040917344,0.00075276365],"genre_scores_gemma":[0.99964315,0.00009503174,0.000011525071,0.00014449134,0.000013181999,0.0000141359005,0.0000024527797,0.000007835828,0.000068187044],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989589,0.00028039512,0.00019954135,0.00023163237,0.00013535479,0.00019421666],"domain_scores_gemma":[0.99925804,0.00021402015,0.000090229325,0.00035915207,0.00001434098,0.00006422281],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015007878,0.00014999472,0.00017660347,0.000047328547,0.00040291532,0.0000395585,0.00016469459,0.00006715176,0.000016956568],"category_scores_gemma":[0.00017553542,0.00010126615,0.000054935033,0.00013285052,0.0001373023,0.00013962794,0.00007088127,0.00014327206,0.0000013125529],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005777575,0.0002433016,0.008289225,0.000004043986,0.0000017334216,0.0000022176637,0.0009075733,2.1610934e-7,0.8877629,0.00017509202,0.0000018895435,0.102554016],"study_design_scores_gemma":[0.00055661815,0.0001086495,0.5360432,0.000006177952,0.000009318234,0.000012445091,0.00033508486,0.0000056692743,0.46256477,0.00019983889,0.00008583154,0.00007235069],"about_ca_topic_score_codex":0.000300292,"about_ca_topic_score_gemma":0.000026119878,"teacher_disagreement_score":0.527754,"about_ca_system_score_codex":0.000014733641,"about_ca_system_score_gemma":0.000011507621,"threshold_uncertainty_score":0.41295138},"labels":[],"label_agreement":null},{"id":"W2071406308","doi":"10.1038/mp.2014.139","title":"Towards a classification of biomarkers of neuropsychiatric disease: from encompass to compass","year":2014,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":121,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Nosology; Disease; Biomarker; Phenome; Trait; Psychology; Medicine; Bioinformatics; Psychiatry; Biology; Pathology; Computer science; Phenotype","score_opus":0.0335868493068501,"score_gpt":0.3175561093842923,"score_spread":0.28396926007744216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071406308","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017749323,0.98708963,0.0041681975,0.0006133543,0.002394738,0.0014310036,0.00060510024,0.00010109188,0.0018219383],"genre_scores_gemma":[0.0198659,0.9730325,0.0048661577,0.0011494518,0.00029659434,0.00022429551,0.00022814995,0.00028330676,0.00005364135],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9956435,0.00080483477,0.0012717836,0.0011414874,0.0007399056,0.00039848976],"domain_scores_gemma":[0.99684894,0.0001786752,0.0010552793,0.0014971278,0.00006172941,0.0003582452],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017704509,0.0006158522,0.0017094599,0.0006819387,0.00006305065,0.000037047706,0.001412892,0.00020783323,0.00007402549],"category_scores_gemma":[0.00028215474,0.00056370115,0.0011032228,0.0017749149,0.00018834978,0.000049428778,0.00017747868,0.000314489,0.00010161371],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024685793,0.0017848093,0.00022976285,0.032024615,0.00041076832,0.00002808046,0.00008933177,0.000029212419,0.0054081082,0.026429417,0.014935509,0.91838354],"study_design_scores_gemma":[0.001022958,0.00028020033,0.0039437027,0.007374746,0.0010916336,0.000010022702,0.000036219815,0.00013615846,0.0005004218,0.0029471614,0.9812654,0.0013913392],"about_ca_topic_score_codex":0.000041807005,"about_ca_topic_score_gemma":0.000007821864,"teacher_disagreement_score":0.96632993,"about_ca_system_score_codex":0.000040254003,"about_ca_system_score_gemma":0.0006190434,"threshold_uncertainty_score":0.9996815},"labels":[],"label_agreement":null},{"id":"W2071703666","doi":"10.1159/000079415","title":"Influence of Chronic Interleukin-2 Infusion and Stressors on Sickness Behaviors and Neurochemical Change in Mice","year":2004,"lang":"en","type":"article","venue":"NeuroImmunoModulation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Anhedonia; Neurochemical; Anorexia; Internal medicine; Stressor; Cytokine; Endocrinology; Sickness behavior; Corticosterone; Chronic stress; Medicine; Hypothalamus; Psychology; Dopamine; Hormone; Psychiatry","score_opus":0.02053919811528912,"score_gpt":0.2678201133848276,"score_spread":0.24728091526953846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071703666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99934024,0.00006668828,0.000005486173,0.00018342602,0.000055230565,0.0002910767,0.000004346057,0.000029769712,0.000023752458],"genre_scores_gemma":[0.9995713,0.00011698525,0.000008646941,0.00025201595,0.000014643518,0.0000144729565,0.000002732789,0.00001518005,0.0000039814145],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990212,0.000057346948,0.00022785264,0.00036349878,0.0001624555,0.00016768555],"domain_scores_gemma":[0.99959904,0.000090964684,0.00010168691,0.0001574948,0.000014740341,0.000036059813],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004652595,0.00013941141,0.0001403385,0.00016929238,0.000048189293,0.000028823935,0.00011431272,0.00005519576,0.0000027376698],"category_scores_gemma":[0.00014871111,0.0001416511,0.00001941702,0.00024832156,0.00015389344,0.00040922122,0.000084865416,0.00017902006,0.0000023099549],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007574606,0.00011833143,0.0036634947,0.000031432104,3.825849e-7,0.000010175299,0.0006024821,0.0027474104,0.98512864,0.00039753187,2.4786084e-7,0.0072241183],"study_design_scores_gemma":[0.0009956011,0.0003212021,0.6871898,0.000104963474,0.0000024736403,0.000015692538,0.000012860262,0.000608471,0.31042528,0.00020179224,0.000012717916,0.00010911326],"about_ca_topic_score_codex":0.00017995268,"about_ca_topic_score_gemma":0.00004807629,"teacher_disagreement_score":0.68352634,"about_ca_system_score_codex":0.00004290869,"about_ca_system_score_gemma":0.00001760706,"threshold_uncertainty_score":0.5776364},"labels":[],"label_agreement":null},{"id":"W2072121441","doi":"10.1016/j.bbr.2011.07.039","title":"Escitalopram reduces circulating pro-inflammatory cytokines and improves depressive behavior without affecting sleep in a rat model of post-cardiac infarct depression","year":2011,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; H. Lundbeck A/S","keywords":"Escitalopram; Anhedonia; Internal medicine; Endocrinology; Corticosterone; Medicine; Psychology; Antidepressant; Anesthesia; Dopamine; Hippocampus","score_opus":0.10626552680929596,"score_gpt":0.34553163174809165,"score_spread":0.2392661049387957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072121441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974756,0.00017593718,0.000012869851,0.00008898041,0.0001009397,0.0016719918,0.000024407582,0.00008546899,0.00036379413],"genre_scores_gemma":[0.99871564,0.000012623388,0.00071122876,0.000035754787,0.000029137174,0.00032994917,0.0000053202666,0.000059392638,0.00010095489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99609286,0.0007483174,0.000525063,0.00088853535,0.00088731304,0.0008579429],"domain_scores_gemma":[0.9982813,0.00063232443,0.0002094431,0.00044307418,0.00022144458,0.00021243928],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012492419,0.00030174208,0.00040417473,0.000608336,0.00036064474,0.0001123134,0.0005108768,0.0002125408,0.00001990069],"category_scores_gemma":[0.0026469,0.00026578418,0.00012297025,0.0005846518,0.0006829232,0.00069505494,0.00058143924,0.0007755502,0.0000039995425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013479129,0.00015878196,0.23855723,0.000056239896,0.0000030772458,0.00003502647,0.0031065666,0.00001748925,0.7431609,0.00006103681,0.000009943135,0.014698889],"study_design_scores_gemma":[0.0007275371,0.0001655246,0.32713613,0.0001467737,0.000010210122,0.000017580149,0.0012310194,0.0018476588,0.6682445,0.0002147902,7.0572366e-7,0.0002576034],"about_ca_topic_score_codex":0.00040590207,"about_ca_topic_score_gemma":0.00007192303,"teacher_disagreement_score":0.088578895,"about_ca_system_score_codex":0.000064278516,"about_ca_system_score_gemma":0.00014871148,"threshold_uncertainty_score":0.99997944},"labels":[],"label_agreement":null},{"id":"W2073023785","doi":"10.1038/nrn3839","title":"The molecular bases of the suicidal brain","year":2014,"lang":"en","type":"review","venue":"Nature reviews. Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":277,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Neurotransmitter systems; Epigenetics; Genetic predisposition; Neuroscience; Psychology; Gene; Medicine; Biology; Genetics","score_opus":0.04313293183519227,"score_gpt":0.35728882106070214,"score_spread":0.31415588922550985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073023785","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000062625,0.99299264,0.00004599466,0.0010155193,0.0021913042,0.0020801423,0.00003752461,0.00005052152,0.0015800738],"genre_scores_gemma":[0.00019931416,0.9888658,0.000016936609,0.00969678,0.000099840596,0.00011310247,0.0000012902391,0.00006034065,0.0009465822],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.992959,0.0027350446,0.0011545719,0.001274103,0.0011475069,0.00072973594],"domain_scores_gemma":[0.993551,0.0026020794,0.0014128193,0.0022356582,0.000052248848,0.00014619973],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015598588,0.0007026851,0.0017505675,0.00012555486,0.0006740784,0.00019367436,0.005338342,0.0004561338,0.0000126798],"category_scores_gemma":[0.025013817,0.0003129943,0.0015526398,0.0028526967,0.0015500698,0.00012753908,0.00069951266,0.0021541803,0.000061033355],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000018301486,0.000044136792,7.108099e-7,0.0049186833,0.0000018308305,0.000009204821,0.00000697948,8.308167e-7,0.0020997429,0.014822769,0.008480282,0.969613],"study_design_scores_gemma":[0.000065438384,0.00004029914,0.000008011156,0.0032892856,0.0000628609,0.000089353955,8.6481367e-7,0.000007712982,0.0010756666,0.00016544631,0.9948739,0.00032115306],"about_ca_topic_score_codex":0.0000029812097,"about_ca_topic_score_gemma":0.000007049495,"teacher_disagreement_score":0.98639363,"about_ca_system_score_codex":0.000043109703,"about_ca_system_score_gemma":0.00041034922,"threshold_uncertainty_score":0.9999322},"labels":[],"label_agreement":null},{"id":"W2073868632","doi":"10.1007/s00213-008-1166-z","title":"Influence of continuous infusion of interleukin-1β on depression-related processes in mice: corticosterone, circulating cytokines, brain monoamines, and cytokine mRNA expression","year":2008,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Corticosterone; Neurochemical; Cytokine; Internal medicine; Endocrinology; Serotonin; Monoamine neurotransmitter; Receptor; Interleukin 6; Dopamine; Medicine; Hormone","score_opus":0.017036019186904543,"score_gpt":0.2865430477621038,"score_spread":0.26950702857519926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073868632","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984176,0.0003505932,0.0000108597715,0.00017965867,0.00017235512,0.000506717,0.000015039463,0.00005114164,0.00029600674],"genre_scores_gemma":[0.9986104,0.0004326651,0.000060457118,0.00076428556,0.000018995855,0.000040931587,0.0000035006353,0.00002678031,0.000041989206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99784994,0.00022095873,0.00078260974,0.00056758325,0.00025239887,0.00032652856],"domain_scores_gemma":[0.9982208,0.0008754102,0.00051870913,0.00019942454,0.00009180031,0.00009385752],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013609143,0.00024863266,0.0004534185,0.00036964915,0.00008745669,0.0000064568676,0.0003075504,0.00016561663,0.00004801845],"category_scores_gemma":[0.00097094476,0.0002220214,0.00004185397,0.00068850286,0.00038913227,0.00020798379,0.00013461117,0.00029555263,0.000004362053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008365523,0.0004179511,0.0414243,0.00016825787,0.0000058227306,0.00006824634,0.0012903099,0.0009759244,0.9529628,0.000010493451,0.00015342809,0.0016859169],"study_design_scores_gemma":[0.0048559047,0.0003243183,0.19677056,0.0003325386,0.000007408553,0.00011563793,0.00006148163,0.00035266258,0.79675555,0.0001161884,0.00010629567,0.0002014572],"about_ca_topic_score_codex":0.00004199556,"about_ca_topic_score_gemma":0.000009765863,"teacher_disagreement_score":0.15620725,"about_ca_system_score_codex":0.000024775578,"about_ca_system_score_gemma":0.00006493205,"threshold_uncertainty_score":0.905377},"labels":[],"label_agreement":null},{"id":"W2073890209","doi":"10.1016/j.bbi.2007.10.012","title":"Acute deviations from long-term trait depressive symptoms predict systemic inflammatory activity","year":2007,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Mood; Trait; Systemic inflammation; Inflammation; C-reactive protein; Internal medicine; Medicine; Interleukin 6; Depressive symptoms; Major depressive disorder; Depressed mood; Psychology; Clinical psychology; Psychiatry; Anxiety","score_opus":0.01910004482557882,"score_gpt":0.2772399996051585,"score_spread":0.2581399547795797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073890209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997143,0.00014392352,0.0010305354,0.0000513743,0.00025329777,0.0005999372,0.0002687637,0.00020249902,0.00030672245],"genre_scores_gemma":[0.99933106,0.00004317252,0.000014643803,0.00023312746,0.000058440946,0.000060019487,0.000036144156,0.00002886658,0.00019454461],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998329,0.00025397912,0.00030974523,0.00042009543,0.00027655167,0.00041063005],"domain_scores_gemma":[0.99845773,0.00064791535,0.00017330011,0.00049622747,0.000036391935,0.00018842859],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002424544,0.0002534674,0.00025113786,0.00013305059,0.00049276295,0.00010496953,0.00038618277,0.0001834677,0.000091979186],"category_scores_gemma":[0.0002493273,0.0002458495,0.000105449566,0.00022204571,0.00028246792,0.00045158458,0.000163771,0.00043093233,0.000017837621],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007504915,0.00024110821,0.1582513,0.000018787186,0.000019409666,0.000081528575,0.0007060734,5.330573e-7,0.81659645,0.0000818272,0.00005859935,0.02386936],"study_design_scores_gemma":[0.00096150074,0.000059425365,0.8473345,0.000051767078,0.000064470245,0.00007149613,0.00007791604,0.000008297455,0.15107736,0.000032634132,0.000027788637,0.00023285097],"about_ca_topic_score_codex":0.00011248132,"about_ca_topic_score_gemma":0.000114255585,"teacher_disagreement_score":0.6890832,"about_ca_system_score_codex":0.00006184564,"about_ca_system_score_gemma":0.0000618938,"threshold_uncertainty_score":0.9999994},"labels":[],"label_agreement":null},{"id":"W2073928762","doi":"10.1016/j.neuropharm.2004.01.001","title":"Dopamine-induced death of PC12 cells is prevented by a substituted tetrahydronaphthalene","year":2004,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"ALS Society of Canada; Muscular Dystrophy Association","keywords":"Dopamine; Programmed cell death; Apoptosis; Chemistry; Oxidative stress; Lipid peroxidation; Intracellular; Biochemistry; Cell biology; Pharmacology; Biology; Endocrinology","score_opus":0.030877153923910602,"score_gpt":0.2910722421959722,"score_spread":0.2601950882720616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073928762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99618435,0.00008362428,0.000049169994,0.0006601526,0.000784204,0.0004382135,0.00008141953,0.00012961429,0.0015892582],"genre_scores_gemma":[0.99602735,0.00014695636,0.000052847485,0.0033237003,0.000047293914,0.000026000935,0.0000035399808,0.000040379116,0.0003319065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99804515,0.00019217875,0.00037602952,0.0006268408,0.00026747544,0.00049233314],"domain_scores_gemma":[0.99913,0.00022450693,0.00017596423,0.0002723311,0.000035702848,0.00016147374],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000061009192,0.00025980244,0.0003099709,0.00015887666,0.00009360692,0.000012030849,0.00050384493,0.000115465016,0.000601521],"category_scores_gemma":[0.00012018432,0.00025669974,0.000120725395,0.0004357577,0.00018125445,0.00013040718,0.00009704875,0.0002956418,0.00015823547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011211621,0.0005823964,0.00006263225,0.00002796611,0.000010633373,0.00017596236,0.000078580146,0.00007013578,0.9972249,0.00027920585,0.0009621183,0.00041334983],"study_design_scores_gemma":[0.0032010358,0.0003188147,0.0007209656,0.000008052536,0.000021103582,0.00006043661,0.0000069958874,0.00005421229,0.99207133,0.00017722796,0.0031511395,0.0002086769],"about_ca_topic_score_codex":0.00004033755,"about_ca_topic_score_gemma":0.0000016236778,"teacher_disagreement_score":0.0051535647,"about_ca_system_score_codex":0.0000409147,"about_ca_system_score_gemma":0.00009728445,"threshold_uncertainty_score":0.9999885},"labels":[],"label_agreement":null},{"id":"W2075847490","doi":"10.1097/01.psy.0000195780.37277.2a","title":"Increased Serum Levels of 8-Hydroxy-2′-Deoxyguanosine in Clinical Depression","year":2006,"lang":"en","type":"article","venue":"Psychosomatic Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":311,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"National Cancer Institute","keywords":"Depression (economics); Internal medicine; Medicine; Biomarker; Body mass index; Pathophysiology; Oxidative stress; Case-control study; 8-Hydroxy-2'-deoxyguanosine; Gastroenterology; Oxidative damage; Biology; DNA oxidation","score_opus":0.051585278984713726,"score_gpt":0.34765313155997063,"score_spread":0.2960678525752569,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075847490","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98162854,0.00025633024,0.0004707169,0.0018605039,0.00038737277,0.00036224065,0.000012374891,0.000064445274,0.014957466],"genre_scores_gemma":[0.9979588,0.0000426465,0.00030080986,0.0012992675,0.0001395396,0.00001215358,0.0000024811034,0.000020447505,0.00022387583],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974318,0.0002887678,0.001091939,0.00042385166,0.00047004235,0.00029360116],"domain_scores_gemma":[0.9983253,0.00078897545,0.000293399,0.00046414533,0.000023256953,0.00010494218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055696047,0.00018305355,0.00048605932,0.00021777039,0.000037791004,0.000005493652,0.00032896758,0.000111964124,0.00072355574],"category_scores_gemma":[0.0014026972,0.00013486667,0.000071529816,0.00059537415,0.00035306707,0.00008795798,0.000037947553,0.00020121221,0.00004670413],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001869693,0.0016108772,0.50709474,0.0003556505,0.000011742144,0.00005352276,0.00036795094,0.000030813673,0.45584524,0.0021721127,0.010290564,0.0219798],"study_design_scores_gemma":[0.004971782,0.00016593268,0.9509246,0.00061644026,0.00001035488,0.00001835887,0.000054583106,0.0013769328,0.034373533,0.006852334,0.00047262007,0.0001625361],"about_ca_topic_score_codex":0.00014566732,"about_ca_topic_score_gemma":0.00002764259,"teacher_disagreement_score":0.44382983,"about_ca_system_score_codex":0.000014324399,"about_ca_system_score_gemma":0.000029950428,"threshold_uncertainty_score":0.7922428},"labels":[],"label_agreement":null},{"id":"W2076578736","doi":"10.1016/j.pnpbp.2011.05.011","title":"Soluble interleukin-2 receptor levels correlated with positive symptoms during quetiapine treatment in schizophrenia-spectrum disorders","year":2011,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Hôpital Louis-H Lafontaine; AstraZeneca (Canada); Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research; AstraZeneca; Eli Lilly and Company","keywords":"Quetiapine; Clozapine; Schizophrenia (object-oriented programming); Positive and Negative Syndrome Scale; Internal medicine; Atypical antipsychotic; Population; Psychology; Medicine; Antipsychotic; Psychiatry; Gastroenterology; Psychosis","score_opus":0.024738323333914573,"score_gpt":0.2757270163497898,"score_spread":0.25098869301587523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076578736","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99323475,0.0012526863,0.000006410151,0.0022679907,0.0014020809,0.0010574047,0.000019006437,0.00017747254,0.00058217277],"genre_scores_gemma":[0.997094,0.0010996416,0.00027345197,0.001097236,0.00007479799,0.00027299926,0.0000057904463,0.00003366342,0.000048461574],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99687386,0.00047055533,0.00052068516,0.0012161675,0.00012422263,0.0007945407],"domain_scores_gemma":[0.9992166,0.00018719229,0.00019388337,0.0002159259,0.000010357825,0.000176029],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012211436,0.0004897411,0.00046082068,0.0003300503,0.00018428777,0.000029933199,0.00038055613,0.00030983245,0.00032437893],"category_scores_gemma":[0.000032376876,0.00034280485,0.00008911922,0.0006911982,0.0009860941,0.00016485137,0.00011378085,0.0006793108,0.000030055584],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014312506,0.0029196488,0.96954894,0.000028136476,0.00004233324,0.000114963914,0.00055466616,0.0000050583426,0.0032179065,0.0018297383,0.00004850792,0.007377569],"study_design_scores_gemma":[0.014952954,0.0034639332,0.9744298,0.000082685896,0.000015276424,0.00007188559,0.000075758064,0.00007194754,0.0033524386,0.0027640334,0.0001827881,0.0005365335],"about_ca_topic_score_codex":0.000023414597,"about_ca_topic_score_gemma":0.00018606591,"teacher_disagreement_score":0.0068410356,"about_ca_system_score_codex":0.000058253238,"about_ca_system_score_gemma":0.00005506372,"threshold_uncertainty_score":0.99990237},"labels":[],"label_agreement":null},{"id":"W2076925873","doi":"10.1016/j.chembiol.2003.09.015","title":"Enzyme-Assisted Suicide","year":2003,"lang":"en","type":"article","venue":"Chemistry & Biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Waterloo; McMaster University","funders":"","keywords":"Enzyme; Biology; Computational biology; Biochemistry","score_opus":0.042319440961693475,"score_gpt":0.2889979455901197,"score_spread":0.24667850462842622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076925873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87448686,0.00020229109,0.00008951534,0.00021644447,0.00015052484,0.000053329135,0.000009476606,0.00011237419,0.124679185],"genre_scores_gemma":[0.99584645,0.000024881952,0.00008093837,0.0010072794,0.000037321224,0.000009731586,0.000007182737,0.000009464884,0.0029767624],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910647,0.000056001616,0.00013070871,0.00036057798,0.000046742098,0.0002995261],"domain_scores_gemma":[0.9994946,0.00012307524,0.000047757363,0.00024700124,0.000011908723,0.000075667056],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000054252505,0.00011874248,0.00012385593,0.000013100843,0.00007314561,0.0000118453645,0.0002055096,0.00013527692,0.0009900661],"category_scores_gemma":[0.0008590178,0.00010663177,0.000057361176,0.00015082557,0.00021934147,0.000022714781,0.000028223598,0.00012600163,0.00015051155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006119047,0.00004098271,0.00041191763,0.0000086613145,0.0000017696877,0.000007732356,0.000011852362,4.1665265e-7,0.9958734,0.0014675749,0.0011879813,0.0009815969],"study_design_scores_gemma":[0.00028995174,0.000011872001,0.00034411505,0.0000027330475,0.0000015475727,0.000054046606,0.000024696124,0.0000039593333,0.9214729,0.0012158545,0.076458775,0.00011953552],"about_ca_topic_score_codex":0.0000031531708,"about_ca_topic_score_gemma":9.3199407e-7,"teacher_disagreement_score":0.12170242,"about_ca_system_score_codex":0.000018030161,"about_ca_system_score_gemma":0.00004245991,"threshold_uncertainty_score":0.99992317},"labels":[],"label_agreement":null},{"id":"W2077050740","doi":"10.1007/s00213-008-1295-4","title":"Lower serum cytokine levels in smokers than nonsmokers with chronic schizophrenia on long-term treatment with antipsychotics","year":2008,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"National Institute on Drug Abuse","keywords":"Schizophrenia (object-oriented programming); Medicine; Cytokine; Psychiatry; Psychosis; Antipsychotic; Psychology; Pharmacology; Internal medicine","score_opus":0.038683734246820915,"score_gpt":0.30571830322926447,"score_spread":0.26703456898244354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077050740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99486357,0.000111821275,0.00006768941,0.0012064168,0.00086208514,0.00091374444,0.000051012765,0.00015266894,0.0017709647],"genre_scores_gemma":[0.9959959,0.0006817418,0.000120655866,0.002172692,0.00016600257,0.00011548884,0.0000049232494,0.00008072791,0.0006618702],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9972234,0.00017985035,0.00032259294,0.0010342599,0.00035083422,0.0008890621],"domain_scores_gemma":[0.99892217,0.00018665334,0.00015603802,0.00047356385,0.000028434855,0.00023314057],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000066254535,0.0005201813,0.00044417244,0.00038611272,0.00022398838,0.000025981368,0.0004146275,0.00014941352,0.00058552844],"category_scores_gemma":[0.000010042081,0.0003799166,0.00009370743,0.0008358903,0.0006371184,0.00016928512,0.000027127979,0.0004122402,0.00020164342],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.07393945,0.009929266,0.41407895,0.00013591883,0.00045140536,0.012134384,0.0017674079,0.0029311234,0.45822594,0.00039247147,0.0026320666,0.02338161],"study_design_scores_gemma":[0.042688493,0.010009888,0.8367626,0.00010815913,0.000052818992,0.0006298217,0.00002554537,0.00013995184,0.107003845,0.00003804365,0.0016368695,0.00090396585],"about_ca_topic_score_codex":0.000017827446,"about_ca_topic_score_gemma":0.0003941833,"teacher_disagreement_score":0.42268363,"about_ca_system_score_codex":0.00030498818,"about_ca_system_score_gemma":0.00025943958,"threshold_uncertainty_score":0.9998653},"labels":[],"label_agreement":null},{"id":"W2077548349","doi":"10.1016/j.expneurol.2013.08.007","title":"The absence of indoleamine 2,3-dioxygenase expression protects against NMDA receptor-mediated excitotoxicity in mouse brain","year":2013,"lang":"en","type":"article","venue":"Experimental Neurology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"","keywords":"Striatum; Neurotoxicity; Excitotoxicity; Neuroprotection; Kynurenine pathway; Indoleamine 2,3-dioxygenase; Quinolinic acid; NMDA receptor; Pharmacology; Kynurenine; Chemistry; Neuroscience; Biology; Dopamine; Internal medicine; Receptor; Medicine; Biochemistry; Toxicity; Tryptophan","score_opus":0.014138012029662098,"score_gpt":0.24806734618315232,"score_spread":0.2339293341534902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077548349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99772817,0.00009708039,0.0000066044327,0.00037539218,0.00021020102,0.0010556896,0.000009734191,0.0000769312,0.00044021063],"genre_scores_gemma":[0.99659115,0.00003764892,0.000032434804,0.0027852554,0.000036896665,0.00031858674,0.000003906909,0.000028289025,0.00016581902],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99786115,0.00051929755,0.0003827635,0.00051070907,0.00025757376,0.000468487],"domain_scores_gemma":[0.998665,0.00064358074,0.0001764235,0.00038973693,0.000018421397,0.000106874366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013054142,0.00021815971,0.00022264871,0.00011064655,0.00016051024,0.00002974199,0.0005057002,0.00013625425,0.00014442096],"category_scores_gemma":[0.0007671932,0.00016352064,0.000060811297,0.00030440904,0.0005138152,0.0002000184,0.00022752259,0.00035106865,0.00013721234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018230708,0.00029906453,0.00012525158,0.0000060946218,0.0000010595882,0.000007548429,0.00039489398,0.000019821755,0.99740833,0.000060711354,0.0011451062,0.00034978206],"study_design_scores_gemma":[0.0010573507,0.00038287268,0.0017626403,0.0000082902425,9.994992e-9,0.0000032608777,0.00019878043,0.00027416725,0.9953468,0.000048616173,0.0007698155,0.00014741078],"about_ca_topic_score_codex":0.000070869544,"about_ca_topic_score_gemma":0.000014449205,"teacher_disagreement_score":0.0024098633,"about_ca_system_score_codex":0.000021161535,"about_ca_system_score_gemma":0.000028574266,"threshold_uncertainty_score":0.66681784},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"agree"},{"id":"W2077713411","doi":"10.1016/j.bbr.2012.11.011","title":"Effects of complete vagotomy and blockage of cell adhesion molecules on interferon-α induced behavioral changes in mice","year":2012,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Deutsche Forschungsgemeinschaft; McMaster University","keywords":"Immune system; Cytokine; Cell adhesion molecule; Immunology; Neuroscience; Medicine; Biology","score_opus":0.14919035569296366,"score_gpt":0.37512162896587475,"score_spread":0.2259312732729111,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077713411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985896,0.00008077001,5.660971e-7,0.0002662256,0.00009923589,0.0007560212,0.000023413791,0.000016161603,0.00016803622],"genre_scores_gemma":[0.99962986,0.0000136904655,0.000047482372,0.00008534414,0.000014274496,0.000042945674,0.0000021279238,0.000025447884,0.00013883182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975496,0.00058107177,0.00024562253,0.00035396195,0.00065904006,0.0006107339],"domain_scores_gemma":[0.9986439,0.0008130204,0.00009386985,0.00024194235,0.000049897477,0.0001573803],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043952212,0.00017228468,0.00026805856,0.0004842755,0.00007264181,0.00001719809,0.00038960186,0.00013372852,0.00002682325],"category_scores_gemma":[0.00038109312,0.00015661196,0.000060036473,0.0005752363,0.00030396512,0.00011534486,0.0003724431,0.00047244356,0.000008535111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012059383,0.0008254856,0.02932825,0.00015558166,5.8818523e-7,0.000011378436,0.0008275611,1.0117056e-7,0.96752226,0.0001182703,0.00006956241,0.0010203841],"study_design_scores_gemma":[0.0008569488,0.00064504985,0.29328313,0.00014167062,0.0000027656167,0.0000021707203,0.00014344939,0.000005960244,0.7047909,0.00001730969,0.000010241113,0.000100392775],"about_ca_topic_score_codex":0.00038445558,"about_ca_topic_score_gemma":0.00012993776,"teacher_disagreement_score":0.26395488,"about_ca_system_score_codex":0.000052331125,"about_ca_system_score_gemma":0.00002937554,"threshold_uncertainty_score":0.63864505},"labels":[],"label_agreement":null},{"id":"W2077761938","doi":"10.1002/dneu.22043","title":"Prenatal and postnatal animal models of immune activation: Relevance to a range of neurodevelopmental disorders","year":2012,"lang":"en","type":"review","venue":"Developmental Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":149,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Autism; Schizophrenia (object-oriented programming); Neuroscience; Disease; Neurochemical; Neurodevelopmental disorder; Immune system; Cerebral palsy; Epilepsy; Biology; Psychology; Psychiatry; Immunology; Medicine; Pathology","score_opus":0.04764802103416053,"score_gpt":0.27922372849482735,"score_spread":0.23157570746066683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077761938","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18853045,0.80366117,0.000084802305,0.00014886753,0.0010026931,0.003723909,0.00082543294,0.00015746642,0.0018652185],"genre_scores_gemma":[0.14011504,0.8579587,0.0011378537,0.00031110147,0.000032159227,0.00013116027,0.000105790314,0.0001068815,0.00010133277],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99689996,0.00028666027,0.0011209646,0.0008823083,0.00023021094,0.0005798887],"domain_scores_gemma":[0.99838316,0.0005676728,0.0005979771,0.0002695712,0.000028972383,0.0001526143],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014391744,0.000607765,0.001430169,0.00041620855,0.00010054966,0.000013240793,0.0006256312,0.00027626887,0.000057073576],"category_scores_gemma":[0.00024696504,0.00055045856,0.00022853323,0.00064030016,0.0004118642,0.00030442167,0.0007649743,0.00037243112,0.000028148626],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060384884,0.00081518583,0.00014502446,0.016793745,0.0001661205,0.000030029161,0.0018603402,0.000006166305,0.03737815,0.0026793764,0.00017046847,0.93935156],"study_design_scores_gemma":[0.006517485,0.0029208236,0.016975269,0.01601718,0.00051672413,0.0038169965,0.0005528704,0.000036748355,0.12590913,0.0005452359,0.81881636,0.0073751453],"about_ca_topic_score_codex":0.000014756352,"about_ca_topic_score_gemma":0.0000048668985,"teacher_disagreement_score":0.9319764,"about_ca_system_score_codex":0.0000650987,"about_ca_system_score_gemma":0.0002468341,"threshold_uncertainty_score":0.9996947},"labels":[],"label_agreement":null},{"id":"W2078699418","doi":"10.1111/j.1601-5215.2010.00508.x","title":"Tryptophan and depression: can diet alone be the answer?","year":2011,"lang":"en","type":"article","venue":"Acta Neuropsychiatrica","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Tryptophan; Mood; Depression (economics); Serotonin; Scientific evidence; Psychology; Medicine; Psychiatry; Internal medicine; Biology; Biochemistry","score_opus":0.0340251887058577,"score_gpt":0.23911211758620446,"score_spread":0.20508692888034677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078699418","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.968212,0.00026325407,0.00001435496,0.005782545,0.0010851223,0.0003401698,0.000022091179,0.00018677682,0.024093688],"genre_scores_gemma":[0.98999673,0.00034405253,0.00014779504,0.008964726,0.0001782503,0.000018346982,9.860889e-7,0.000037507118,0.0003116088],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99832094,0.00019727641,0.0002125878,0.0005898142,0.0002808268,0.00039855778],"domain_scores_gemma":[0.9988831,0.00020797353,0.000106234256,0.00061698887,0.000018067578,0.00016762316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007397879,0.00022554085,0.00016490802,0.00008647726,0.00040367452,0.000064920416,0.0005849819,0.00006497362,0.00016465425],"category_scores_gemma":[0.00027823754,0.00014932777,0.00007642879,0.00052559556,0.00023666001,0.00013439095,0.00017699452,0.0002885969,0.000022699613],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003851335,0.0033877431,0.055743862,0.00019767146,0.000093558556,0.0007252007,0.024375884,0.000004122605,0.5355511,0.016470565,0.2702999,0.089299105],"study_design_scores_gemma":[0.0050031273,0.0019361674,0.6333603,0.000033405708,0.000115409355,0.00048824697,0.0012836644,0.0002619751,0.116302915,0.0074557243,0.23195738,0.0018016553],"about_ca_topic_score_codex":0.000060878163,"about_ca_topic_score_gemma":0.00002830924,"teacher_disagreement_score":0.57761645,"about_ca_system_score_codex":0.000005594129,"about_ca_system_score_gemma":0.00003259629,"threshold_uncertainty_score":0.60894096},"labels":[],"label_agreement":null},{"id":"W2079421033","doi":"10.1016/j.jalz.2008.05.653","title":"P1‐067: Age‐, sex‐ and transgene‐dependent biphasic alterations of social behavior in triple‐transgenic 3XTg‐AD mice","year":2008,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Apathy; Disinhibition; Transgene; Genetically modified mouse; Presenilin; Psychology; Frontal cortex; Internal medicine; Cortex (anatomy); Disease; Endocrinology; Physiology; Developmental psychology; Biology; Alzheimer's disease; Neuroscience; Medicine; Genetics","score_opus":0.05226531382367816,"score_gpt":0.2868728601293179,"score_spread":0.23460754630563974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079421033","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928951,0.0052858233,0.000151441,0.00022915337,0.00021230702,0.0005669191,0.000053891537,0.00004738804,0.00055794255],"genre_scores_gemma":[0.9989307,0.00031009442,0.0002291128,0.00032293037,0.000029839191,0.00008103102,0.000013108827,0.000027569555,0.0000556412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982506,0.00014724978,0.00044382646,0.00047446685,0.0003201447,0.00036373397],"domain_scores_gemma":[0.99956495,0.000060870992,0.000093607574,0.00018184682,0.000017765631,0.00008094449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011530428,0.00021257986,0.00026010495,0.00018592869,0.00025915826,0.000030924944,0.00025835584,0.00009544061,0.00023375519],"category_scores_gemma":[0.000012996983,0.00022754306,0.000121228826,0.00034481354,0.00026809255,0.00022384309,0.000034077933,0.00016589121,0.00001776037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007158715,0.0005620525,0.0020982244,0.000010274318,0.00037294521,0.00007384134,0.0052194325,0.0000104307,0.9756162,0.0004535183,0.00038052333,0.0151309725],"study_design_scores_gemma":[0.003222876,0.00020194017,0.0751126,0.000007618145,0.0014852312,0.000033682947,0.00022723511,0.000052801814,0.91774416,0.00012553619,0.0013420322,0.00044427186],"about_ca_topic_score_codex":0.00006514576,"about_ca_topic_score_gemma":0.00035967506,"teacher_disagreement_score":0.07301438,"about_ca_system_score_codex":0.000005072385,"about_ca_system_score_gemma":0.00006594851,"threshold_uncertainty_score":0.9278937},"labels":[],"label_agreement":null},{"id":"W2079768378","doi":"10.2174/1567205054367883","title":"Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Other Anti- Inflammatory Agents in the Treatment of Neurodegenerative Disease","year":2005,"lang":"en","type":"review","venue":"Current Alzheimer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Anti-inflammatory; Medicine; Disease; Pharmacology; Inflammation; Immunology; Internal medicine","score_opus":0.2868608985748374,"score_gpt":0.4566297959493554,"score_spread":0.169768897374518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079768378","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04732575,0.9485733,5.348366e-7,0.00006697038,0.00031754814,0.0032059494,0.0001669209,0.000026719788,0.00031631836],"genre_scores_gemma":[0.01272953,0.9861642,0.0000032698429,0.000047545207,0.00033383069,0.00052439666,0.00002398382,0.000096939795,0.00007631113],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9934934,0.0022332668,0.0008680247,0.0011850349,0.0013161883,0.000904123],"domain_scores_gemma":[0.9974836,0.00083617604,0.00029866915,0.0010095866,0.00007231194,0.00029967204],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000848378,0.00067923224,0.0011780245,0.00086163246,0.0002726074,0.0001782696,0.0011096002,0.00017015774,0.00008800751],"category_scores_gemma":[0.00013493937,0.0004419572,0.00042722275,0.00093582843,0.00095574325,0.0002004931,0.00025695437,0.00083243725,0.00018201488],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038164184,0.0012809839,0.0006533731,0.0022930796,0.00011390836,0.00008701644,0.0024536178,0.0000050331287,0.000051996598,0.00025886018,0.001045895,0.99171805],"study_design_scores_gemma":[0.0008798412,0.00014552996,0.00090294704,0.0017559497,0.00020901902,0.0000055621576,0.00009381136,0.00007178555,0.0003169839,0.000021359658,0.99515903,0.00043815988],"about_ca_topic_score_codex":0.000011698971,"about_ca_topic_score_gemma":0.000010351049,"teacher_disagreement_score":0.99411315,"about_ca_system_score_codex":0.000095970965,"about_ca_system_score_gemma":0.0005399408,"threshold_uncertainty_score":0.99980325},"labels":[],"label_agreement":null},{"id":"W2079819775","doi":"10.1016/j.pnpbp.2010.06.020","title":"Cytokines mediated inflammation and decreased neurogenesis in animal models of depression","year":2010,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":294,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"Canada Research Chairs","keywords":"Neurogenesis; Neuroinflammation; Neurotrophic factors; Neurotrophin; Proinflammatory cytokine; Inflammation; Microglia; Brain-derived neurotrophic factor; Neuroscience; Cytokine; Neuroprotection; Psychology; Endocrinology; Internal medicine; Medicine; Receptor","score_opus":0.05105245447302214,"score_gpt":0.35019377364711485,"score_spread":0.2991413191740927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079819775","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4285785,0.5696508,0.0000011689416,0.00018370786,0.0005459503,0.0009008323,0.00003548546,0.000050536215,0.0000529538],"genre_scores_gemma":[0.13720958,0.8618051,0.00013457482,0.00042235377,0.00011209249,0.00026342671,0.000018688012,0.00003299211,0.0000011866061],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9961235,0.0009809509,0.0010223514,0.0012184187,0.00016787037,0.00048692574],"domain_scores_gemma":[0.99789375,0.0011365409,0.0005405885,0.00023583548,0.000022551554,0.00017075377],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031531387,0.0005658578,0.0012778939,0.0005500493,0.000084621075,0.000027187507,0.00047164483,0.001009041,0.000030652052],"category_scores_gemma":[0.00031133898,0.00040436233,0.00016134715,0.000762059,0.00084593496,0.00014891033,0.00022242223,0.0011304553,0.0000029736755],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014065433,0.00095187675,0.13650684,0.0035862534,0.00002077231,0.000087510496,0.000042064126,0.0000019313657,0.0027502647,0.0007000587,0.00005476879,0.85389113],"study_design_scores_gemma":[0.037901875,0.004618163,0.6726837,0.012784393,0.00089607784,0.0009891281,0.00008494544,0.0040322756,0.0013030975,0.024277728,0.23365864,0.0067699277],"about_ca_topic_score_codex":0.0000021746202,"about_ca_topic_score_gemma":0.000011743351,"teacher_disagreement_score":0.8471212,"about_ca_system_score_codex":0.000008858038,"about_ca_system_score_gemma":0.00009276676,"threshold_uncertainty_score":0.9998408},"labels":[],"label_agreement":null},{"id":"W2080287150","doi":"10.1139/o11-077","title":"Changes in the levels of thioredoxin and indoleamine-2,3-dioxygenase activity in plasma of patients with colorectal cancer treated with chemotherapy","year":2012,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Junta de Castilla y León","keywords":"Indoleamine 2,3-dioxygenase; Oxidative stress; Malondialdehyde; Colorectal cancer; Kynurenine; Chemotherapy; Medicine; Internal medicine; Monoclonal antibody; Cancer; Thioredoxin; Pharmacology; Antibody; Immunology; Chemistry; Tryptophan; Biochemistry","score_opus":0.013560770614507882,"score_gpt":0.2298184344005018,"score_spread":0.2162576637859939,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080287150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9994024,0.00011086595,3.8883263e-7,0.000040916035,0.000006024998,0.00014344483,0.000078501216,0.0000031350903,0.00021434038],"genre_scores_gemma":[0.99980783,0.00008382129,0.000008091486,0.000055012923,0.000008058409,0.000016660548,0.0000032784278,0.000004378589,0.000012886446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995067,0.0000564572,0.00007165349,0.00016295776,0.000046552603,0.00015567515],"domain_scores_gemma":[0.99972314,0.00009256682,0.00008023724,0.00006990141,0.000009255608,0.00002488366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006032556,0.00009861747,0.00014423471,0.000027925887,0.000015766796,0.0000022950517,0.00007036994,0.000085016545,0.000010638915],"category_scores_gemma":[0.000014582145,0.000056818855,0.0000072699368,0.00014372476,0.0002840725,0.000025254387,0.000015615062,0.00007294247,5.1508515e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051981653,0.00020778249,0.21488759,0.00004042672,0.0000023446225,4.483299e-7,0.00035630495,2.465918e-7,0.78189594,0.0000035153553,0.0000011050001,0.0020844843],"study_design_scores_gemma":[0.0011266355,0.00016581624,0.3271904,0.000010296022,0.0000011581483,8.8116144e-7,0.000107101405,0.0000035508308,0.67132944,0.0000014825947,0.000012206037,0.00005102111],"about_ca_topic_score_codex":0.00005014391,"about_ca_topic_score_gemma":0.000093536386,"teacher_disagreement_score":0.112302825,"about_ca_system_score_codex":0.000006801953,"about_ca_system_score_gemma":0.00001690467,"threshold_uncertainty_score":0.23170057},"labels":[],"label_agreement":null},{"id":"W2080647566","doi":"10.1016/j.jpsychores.2014.07.012","title":"C-reactive protein, depressive symptoms, and risk of diabetes: Results from the English Longitudinal Study of Ageing (ELSA)","year":2014,"lang":"en","type":"article","venue":"Journal of Psychosomatic Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; University College London","keywords":"Diabetes mellitus; Medicine; Depression (economics); Internal medicine; Hazard ratio; Center for Epidemiologic Studies Depression Scale; Incidence (geometry); Longitudinal study; Prospective cohort study; C-reactive protein; Proportional hazards model; Type 2 diabetes; Depressive symptoms; Endocrinology; Confidence interval; Inflammation; Pathology","score_opus":0.06337829305857308,"score_gpt":0.3501066305035248,"score_spread":0.28672833744495174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080647566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99810135,0.00017665017,0.000067164045,0.00017245919,0.00013547704,0.00069020333,0.000024848223,0.000005897916,0.0006259547],"genre_scores_gemma":[0.9996095,0.000045365057,0.0001085124,0.00001366762,0.0001745696,0.0000137197385,2.2298958e-7,0.000015827278,0.000018665505],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.994749,0.0022718254,0.000852981,0.0003042787,0.0015003758,0.00032155702],"domain_scores_gemma":[0.99076205,0.0069222376,0.0010908536,0.0005161823,0.000586012,0.00012267007],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0028948684,0.00014230596,0.0004146155,0.00024101337,0.00020387878,0.00008359659,0.0007751947,0.00006393102,0.000015151393],"category_scores_gemma":[0.01892353,0.00008736192,0.00009518089,0.00057911826,0.00043401422,0.00026999283,0.00014450739,0.0007957476,0.00000194],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017867566,0.0034832165,0.66156137,0.00023375616,0.0006652462,0.000051404473,0.066872105,0.00010570897,0.2438087,0.0002992445,0.0014935932,0.0196389],"study_design_scores_gemma":[0.0057824156,0.0026715384,0.92842925,0.0009212782,0.0000576794,0.000003638322,0.0070902617,0.00044806077,0.046314247,0.008070283,0.00007292313,0.00013841216],"about_ca_topic_score_codex":0.00016916089,"about_ca_topic_score_gemma":0.00004606092,"teacher_disagreement_score":0.2668679,"about_ca_system_score_codex":0.00002218303,"about_ca_system_score_gemma":0.00006156812,"threshold_uncertainty_score":0.9893405},"labels":[],"label_agreement":null},{"id":"W2081306572","doi":"10.1016/j.jpsychires.2013.06.008","title":"Effects of doxycycline on depressive-like behavior in mice after lipopolysaccharide (LPS) administration","year":2013,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":196,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Doxycycline; Pharmacology; Behavioural despair test; Lipid peroxidation; Oxidative stress; Lipopolysaccharide; Imipramine; Minocycline; Antidepressant; Chemistry; Hippocampus; Medicine; Endocrinology; Biochemistry; Antibiotics","score_opus":0.030165489083779435,"score_gpt":0.3531656019436941,"score_spread":0.3230001128599147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081306572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971227,0.00043085203,0.000027508846,0.0009725012,0.00048627533,0.00053510885,0.0000020326795,0.000005392027,0.00041764247],"genre_scores_gemma":[0.99878347,0.0002703448,0.0002763427,0.0001829609,0.00020687004,0.00005454857,1.8127695e-7,0.000016997485,0.00020829844],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99715734,0.0005104487,0.0006285847,0.00024717167,0.0010811,0.00037537076],"domain_scores_gemma":[0.99814206,0.0010002465,0.00030479953,0.00019474963,0.00019505832,0.00016306432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006399641,0.00012525936,0.0002389122,0.0010008429,0.00006158418,0.00007063428,0.00048554767,0.00010398808,0.000162555],"category_scores_gemma":[0.00094403955,0.00009792115,0.00013726308,0.00078198273,0.00012560344,0.00026566963,0.000050898474,0.0007625517,0.00007121021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013212227,0.0021386081,0.017618906,0.00017925698,0.000008686702,0.0002701496,0.0002322775,0.00001315179,0.9632158,0.00027465675,0.0043525975,0.0103746345],"study_design_scores_gemma":[0.0028366195,0.002760772,0.4275208,0.00013191499,0.000017847367,0.000074349526,0.00014163989,0.00005509707,0.56450564,0.0015948577,0.00018056415,0.00017988401],"about_ca_topic_score_codex":0.000068343856,"about_ca_topic_score_gemma":0.000022599193,"teacher_disagreement_score":0.40990192,"about_ca_system_score_codex":0.000048952963,"about_ca_system_score_gemma":0.0001945542,"threshold_uncertainty_score":0.39931086},"labels":[],"label_agreement":null},{"id":"W2081342988","doi":"10.1503/cmaj.071569","title":"The dietary supplement 5-hydroxytryptophan and urinary 5-hydroxyindole acetic acid","year":2008,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Diarrhea; Medicine; Feces; Urinary system; Fecal incontinence; Internal medicine; Disease; Gastroenterology; Biology; Microbiology","score_opus":0.015011660391237783,"score_gpt":0.23389139309522397,"score_spread":0.2188797327039862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081342988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9161632,0.0007479787,0.000017734592,0.07886863,0.00094166497,0.00016022414,0.000023064276,0.000030019744,0.0030474898],"genre_scores_gemma":[0.984256,0.0016671045,0.000029225674,0.012547312,0.0005917422,0.000007905112,0.0000020310656,0.000014847284,0.0008838085],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973083,0.00029191002,0.00033119286,0.0002181514,0.0011905619,0.00065988215],"domain_scores_gemma":[0.997972,0.00037314024,0.00014432879,0.0001290519,0.00005814442,0.0013233039],"candidate_categories":["sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007471589,0.00013828653,0.00014794125,0.0000979716,0.0017463475,0.00011410654,0.00037455227,0.000176024,0.0012338181],"category_scores_gemma":[0.0021699674,0.00010331165,0.00007825887,0.00021474996,0.00021102183,0.00015053435,0.000045183308,0.0007496358,0.00012753895],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007390532,0.0003006753,0.057195146,0.000024587214,0.00014652964,0.0070807515,0.0038925256,0.000011745309,0.008821648,0.0028909745,0.8333794,0.08618213],"study_design_scores_gemma":[0.002396787,0.0002776335,0.09467108,0.000039978862,0.000012753217,0.005898504,0.00078459916,0.00064093235,0.004193685,0.0019450925,0.8887146,0.00042435914],"about_ca_topic_score_codex":0.00030096737,"about_ca_topic_score_gemma":0.0032903063,"teacher_disagreement_score":0.08575777,"about_ca_system_score_codex":0.00033254945,"about_ca_system_score_gemma":0.0010860197,"threshold_uncertainty_score":0.9996792},"labels":[],"label_agreement":null},{"id":"W2081409519","doi":"10.1027/0838-1925.15.2.68","title":"Immunologic Investigations in Neurological and Psychiatric Diseases","year":2003,"lang":"en","type":"article","venue":"Allergy & Clinical Immunology International - Journal of the World Allergy Organization","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Psychiatry; Medicine; Psychology","score_opus":0.024055359178761348,"score_gpt":0.2919250332354246,"score_spread":0.2678696740566633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081409519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.977204,0.00096934114,0.0001593144,0.01713616,0.0037630298,0.00012260675,0.000003823122,0.000034228648,0.00060748175],"genre_scores_gemma":[0.99156904,0.0030089172,0.00031992755,0.0045067533,0.0001330476,0.0000027177823,0.0000025525555,0.000021389926,0.00043563065],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99705666,0.001048192,0.0010262682,0.0003248496,0.00031575616,0.00022827684],"domain_scores_gemma":[0.9975345,0.0011799169,0.0006990405,0.00023810407,0.000269252,0.000079146244],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.00033789928,0.0001841864,0.00028745842,0.0003544087,0.000170698,0.00006692662,0.00097523764,0.00015176424,0.0004357857],"category_scores_gemma":[0.013121828,0.00013191182,0.000146092,0.0009686627,0.0006335713,0.0002696965,0.00022152193,0.000671738,0.00002162686],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00070063706,0.0034980446,0.5719344,0.000005937205,0.0010576969,0.0001866466,0.0003500319,0.0028445758,0.020595774,0.38666168,0.0057962732,0.006368272],"study_design_scores_gemma":[0.002554844,0.0002612767,0.9365284,0.00003978744,0.00002097298,0.000333705,0.000063590516,0.00010880454,0.002248656,0.028192775,0.029399537,0.00024763838],"about_ca_topic_score_codex":0.000004894615,"about_ca_topic_score_gemma":0.000089562585,"teacher_disagreement_score":0.36459398,"about_ca_system_score_codex":0.000039973613,"about_ca_system_score_gemma":0.00017167257,"threshold_uncertainty_score":0.99519104},"labels":[],"label_agreement":null},{"id":"W2081538358","doi":"10.1021/jm800143h","title":"Synthesis of Indoleamine 2,3-Dioxygenase Inhibitory Analogues of the Sponge Alkaloid Exiguamine A","year":2008,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Sponge; Indoleamine 2,3-dioxygenase; Natural product; Alkaloid; In vitro; Stereochemistry; Biochemistry; Tryptophan; Amino acid; Botany","score_opus":0.022322510675809606,"score_gpt":0.2323618263124414,"score_spread":0.2100393156366318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081538358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99688363,0.00073407666,0.000011265148,0.0003920375,0.0001225496,0.00004866963,0.000015985586,0.000005724226,0.0017860577],"genre_scores_gemma":[0.9989079,0.00027059708,0.000057579968,0.00020332402,0.00030292876,0.0000011369553,3.8313144e-7,0.000012398778,0.0002437081],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808913,0.00008191971,0.0006830485,0.00014364299,0.0008218161,0.00018045337],"domain_scores_gemma":[0.9980946,0.00047518514,0.00087348337,0.00026290468,0.0001714501,0.00012236997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034424785,0.00014964749,0.00042253165,0.00007592329,0.00006001719,0.000002658334,0.0005356666,0.00009189886,0.00011735146],"category_scores_gemma":[0.0037252838,0.000095138836,0.00023833237,0.00034183243,0.000682825,0.00008450025,0.000063511114,0.0003667829,0.0000011188226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020257688,0.00021915845,0.0004298216,0.00018435481,0.000017725995,0.0001564786,0.0002731614,0.000008912368,0.99594915,0.0000033058343,0.0017619599,0.00079339655],"study_design_scores_gemma":[0.0007814477,0.00010306029,0.006513738,0.00036483986,0.000017643477,0.0012314342,0.00052092696,0.000008870329,0.9899149,0.000033911252,0.000426892,0.00008232062],"about_ca_topic_score_codex":0.0000065655295,"about_ca_topic_score_gemma":9.0890194e-7,"teacher_disagreement_score":0.0060839164,"about_ca_system_score_codex":0.000034709712,"about_ca_system_score_gemma":0.00022821836,"threshold_uncertainty_score":0.44597816},"labels":[],"label_agreement":null},{"id":"W2082058677","doi":"10.1037/a0014477","title":"Behavioral and neurobiological changes in C57BL/6 mice exposed to cuprizone.","year":2009,"lang":"en","type":"article","venue":"Behavioral Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":135,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Southern Illinois University","keywords":"Prepulse inhibition; Prefrontal cortex; Dopamine; Psychology; Internal medicine; Hippocampus; Endocrinology; Central nervous system; Neuroscience; Myelin; Schizophrenia (object-oriented programming); Medicine; Psychiatry","score_opus":0.09935633401025828,"score_gpt":0.33313614006672215,"score_spread":0.23377980605646387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082058677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99660116,0.000018720462,0.00001977048,0.0020140028,0.00044483732,0.0005402268,0.00001872488,0.00017964216,0.00016290849],"genre_scores_gemma":[0.99122566,0.00003637609,0.00017285853,0.008227159,0.000029506617,0.000029130106,0.0000010380807,0.000015968753,0.0002622976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972001,0.00015593236,0.00027411297,0.0012168284,0.00036930208,0.0007837332],"domain_scores_gemma":[0.99916315,0.000060295533,0.00007113966,0.00034650546,0.000018564448,0.00034036997],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014638594,0.00030730182,0.0002711711,0.00029757904,0.00021131532,0.00018262064,0.0007011917,0.000103700026,0.000025435937],"category_scores_gemma":[0.000207704,0.00027829778,0.000050604205,0.0011483378,0.0003538572,0.00032753727,0.00020256352,0.0003129905,0.000030651772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040944633,0.000497673,0.0022730057,0.0000015617802,2.2126859e-8,0.0001641552,0.00019645515,0.00000709798,0.98364276,0.00018481552,0.00008722882,0.0129042575],"study_design_scores_gemma":[0.00097085454,0.0038230782,0.35422856,0.000027224389,0.000006104625,0.0001559375,0.00011991201,0.00011132156,0.6367231,0.0002249745,0.0029038594,0.0007050699],"about_ca_topic_score_codex":0.000028379693,"about_ca_topic_score_gemma":0.000081476486,"teacher_disagreement_score":0.35195553,"about_ca_system_score_codex":0.000029991472,"about_ca_system_score_gemma":0.00003207518,"threshold_uncertainty_score":0.9999669},"labels":[],"label_agreement":null},{"id":"W2082485125","doi":"10.1016/j.jalz.2011.03.012","title":"Nonsteroidal anti‐inflammatory drug use and the risk of cognitive impairment and Alzheimer's disease","year":2012,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa; Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Dementia; Medicine; Hazard ratio; Incidence (geometry); Internal medicine; Confidence interval; Disease; Cohort study; Observational study; Cohort; Population; Alzheimer's disease; Proportional hazards model; Vascular dementia; Environmental health","score_opus":0.02051004388995043,"score_gpt":0.24598086316824863,"score_spread":0.2254708192782982,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082485125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93496263,0.06374453,0.000020440342,0.00018024896,0.00018893137,0.00064675114,0.000076902135,0.00003563185,0.00014392102],"genre_scores_gemma":[0.99838036,0.00086508284,0.00005601053,0.00057910674,0.000051131658,0.000037696223,0.000003994682,0.000022858421,0.0000037278685],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983218,0.00040789356,0.00027891152,0.000327526,0.00027382927,0.0003900918],"domain_scores_gemma":[0.9985096,0.00074535754,0.00020611542,0.00025005083,0.00003271156,0.0002561975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003961944,0.00022123186,0.00021071214,0.00006534084,0.00025490642,0.000084927735,0.00015301861,0.000036606154,0.0000625548],"category_scores_gemma":[0.00019478089,0.00015443776,0.00008981378,0.0001087081,0.00094487274,0.00057035254,0.00023245969,0.0001436821,0.000020896721],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011817872,0.00074652117,0.9508597,0.000018991213,0.00579826,0.000018432089,0.007035662,0.0000051825427,0.0037221536,0.004357211,0.0016548645,0.024601232],"study_design_scores_gemma":[0.004056318,0.00004544201,0.9256785,0.00004195039,0.011500838,0.000010279145,0.00058284006,0.00019439058,0.05650778,0.00028733452,0.00073785876,0.00035647725],"about_ca_topic_score_codex":0.00006270753,"about_ca_topic_score_gemma":0.00001033274,"teacher_disagreement_score":0.06341775,"about_ca_system_score_codex":0.0000010508274,"about_ca_system_score_gemma":0.000026644138,"threshold_uncertainty_score":0.6297789},"labels":[],"label_agreement":null},{"id":"W2083167029","doi":"10.1016/j.neuropharm.2011.02.022","title":"Prenatal exposure to a viral mimetic alters behavioural flexibility in male, but not female, rats","year":2011,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression; University of Saskatchewan; Saskatchewan Health Research Foundation; Hope for Depression Research Foundation","keywords":"Offspring; Schizophrenia (object-oriented programming); Cognitive flexibility; Pregnancy; Prefrontal cortex; In utero; Prepulse inhibition; Executive functions; Physiology; Fetus; Medicine; Psychology; Cognition; Internal medicine; Psychiatry; Biology","score_opus":0.07560904591374729,"score_gpt":0.30637685487709054,"score_spread":0.23076780896334326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083167029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958602,0.000020173831,0.0000093092485,0.00030422022,0.0013486041,0.000804233,0.000045724555,0.00013820137,0.0014693276],"genre_scores_gemma":[0.9879731,0.000011460435,0.00016410457,0.010865554,0.00007015617,0.0001162094,0.0000018461095,0.000040435934,0.00075714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99696213,0.0005837435,0.0004317041,0.0010029149,0.00024573124,0.0007738059],"domain_scores_gemma":[0.99898565,0.00023560692,0.0000912098,0.00038545867,0.00002750305,0.00027455427],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016126715,0.0003026246,0.00031546137,0.00028180247,0.000098077355,0.0000252178,0.00066024094,0.00011669887,0.0013742378],"category_scores_gemma":[0.00036549475,0.00030435965,0.00010373021,0.0004329049,0.0002724113,0.00021165969,0.0002786481,0.0004761739,0.00045846912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010425121,0.0005182938,0.010622216,0.00002977218,0.0000033768683,0.0012734843,0.00079870876,0.000036962338,0.9837102,0.0001053267,0.0003497528,0.0015093731],"study_design_scores_gemma":[0.0015350007,0.0007255715,0.17833716,0.000007124477,0.000012486054,0.0001110309,0.000041548843,0.0000687051,0.81870973,0.000036545243,0.00013677131,0.0002783311],"about_ca_topic_score_codex":0.000114024784,"about_ca_topic_score_gemma":0.000041493255,"teacher_disagreement_score":0.16771494,"about_ca_system_score_codex":0.0000538125,"about_ca_system_score_gemma":0.00006579472,"threshold_uncertainty_score":0.9999409},"labels":[],"label_agreement":null},{"id":"W2083947971","doi":"10.1016/j.febslet.2006.03.034","title":"Cytochrome <i>b</i><sub>5</sub> is a major reductant in vivo of human indoleamine 2,3‐dioxygenase expressed in yeast","year":2006,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research; Canadian Blood Services","keywords":"Indoleamine 2,3-dioxygenase; Yeast; Chemistry; In vivo; Cytochrome; Biochemistry; Biology; Tryptophan; Enzyme; Genetics; Amino acid","score_opus":0.012450699084111129,"score_gpt":0.22582469368308658,"score_spread":0.21337399459897546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083947971","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971042,0.000031280295,0.000015609332,0.0015915029,0.00007538961,0.00036646958,0.000092288785,0.000049842198,0.00067338726],"genre_scores_gemma":[0.9955066,0.0000064987776,0.000045646,0.004224672,0.0000791719,0.000044175704,0.0000057712064,0.000036541973,0.00005093958],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979952,0.0001200575,0.0004895229,0.0005569406,0.00034601032,0.00049227243],"domain_scores_gemma":[0.9993206,0.00006214034,0.00015274386,0.0003931409,0.000011803496,0.000059533595],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012716629,0.00023669717,0.00031812306,0.00043201726,0.00005066263,0.000032279648,0.0003731921,0.00008406635,0.00007619153],"category_scores_gemma":[0.000073025985,0.00024690473,0.000094530784,0.00075813354,0.0002272808,0.00018457139,0.00008147985,0.00023152267,0.00002942864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059247068,0.00026165342,0.00036286534,0.00004511236,0.0000019084678,0.00016712902,0.00041397935,0.000054404496,0.99126506,0.000107407286,0.0071635027,0.00009772943],"study_design_scores_gemma":[0.0018981311,0.00005108079,0.02106227,0.00009223058,0.0000017146065,0.00000861934,0.00007284633,0.000025958923,0.9760537,0.00019425442,0.00028379928,0.000255384],"about_ca_topic_score_codex":0.00027428564,"about_ca_topic_score_gemma":0.00021091993,"teacher_disagreement_score":0.020699406,"about_ca_system_score_codex":0.000073542324,"about_ca_system_score_gemma":0.000028456296,"threshold_uncertainty_score":0.99999833},"labels":[],"label_agreement":null},{"id":"W2084567714","doi":"10.3109/08039488.2012.700947","title":"Limitation of pro- and anti-inflammatory cytokine analysis to discriminate biological stress effects in patients suffering from chronic psychological distress","year":2012,"lang":"en","type":"article","venue":"Nordic Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University","funders":"","keywords":"Medicine; Distress; Cytokine; Coping (psychology); Immune system; Depression (economics); Clinical psychology; Quality of life (healthcare); Psychological distress; Chronic stress; Tumor necrosis factor alpha; Psychiatry; Anxiety; Internal medicine; Immunology","score_opus":0.019201258236339266,"score_gpt":0.2790155567688275,"score_spread":0.2598142985324882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084567714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99802506,0.0004588396,0.00054583856,0.0001686739,0.00054038747,0.0001822385,0.000033856668,0.000008810975,0.000036271027],"genre_scores_gemma":[0.99905175,0.00007786079,0.00060133287,0.000094367424,0.00015332116,0.0000039560896,0.000006790925,0.000009118099,0.0000015119857],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984443,0.00022430427,0.00051591406,0.00023509128,0.00028574865,0.00029461997],"domain_scores_gemma":[0.9990868,0.00019559519,0.0003530761,0.0001566726,0.000035720564,0.00017211659],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018769912,0.00016163333,0.0003936538,0.00033413502,0.000043695087,0.000020083113,0.00023649227,0.00009932132,0.000017388327],"category_scores_gemma":[0.00027155768,0.00011712833,0.00014118277,0.0005092367,0.000104525185,0.00021326795,0.00006311657,0.00024497218,0.000003037837],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012587872,0.00074740796,0.97590756,0.000050195962,0.00004733949,0.000003492155,0.0003223964,0.0001168664,0.018096935,0.00020045026,0.00002179466,0.0043596923],"study_design_scores_gemma":[0.0013805189,0.00048557523,0.99393845,0.00011454413,0.00007126221,0.0000022005875,0.000120451856,0.000031394757,0.003417,0.00030091562,0.000007815702,0.00012984732],"about_ca_topic_score_codex":0.0000076109122,"about_ca_topic_score_gemma":0.000032583157,"teacher_disagreement_score":0.018030923,"about_ca_system_score_codex":0.00003740823,"about_ca_system_score_gemma":0.000016139118,"threshold_uncertainty_score":0.47763547},"labels":[],"label_agreement":null},{"id":"W2084881641","doi":"10.1039/c2mb25118c","title":"Combining redox-proteomics and epigenomics to explain the involvement of oxidative stress in psychiatric disorders","year":2012,"lang":"en","type":"review","venue":"Molecular BioSystems","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Oxidative stress; Epigenetics; Epigenomics; Schizophrenia (object-oriented programming); Proteomics; DNA methylation; Bipolar disorder; Bioinformatics; DNA damage; Psychiatry; Biology; Neuroscience; Computational biology; Medicine; DNA; Genetics; Biochemistry; Gene; Cognition","score_opus":0.036569112776316866,"score_gpt":0.28745458452933315,"score_spread":0.2508854717530163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084881641","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013830543,0.9810932,0.00043350089,0.00009795785,0.0004760691,0.0036128548,0.00014235669,0.000024708592,0.00028876675],"genre_scores_gemma":[0.05041213,0.94856936,0.00033233993,0.00015172349,0.00004730123,0.00035147122,0.000023420665,0.00008920249,0.000023024038],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970026,0.00077801896,0.00081770733,0.0006232029,0.00031721356,0.0004612302],"domain_scores_gemma":[0.99848455,0.0002183533,0.0005290143,0.00062653463,0.0000168021,0.00012476895],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005277106,0.00044927446,0.0010082083,0.00039848068,0.00010046986,0.000060751143,0.0006963289,0.00021564159,0.000003942896],"category_scores_gemma":[0.00014320473,0.0003303669,0.00022690414,0.0009455411,0.00012478286,0.00005411825,0.00029816767,0.00033562857,0.000014023376],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011662868,0.0015901986,0.0005022348,0.06272981,0.00035597215,0.000052510473,0.0109053515,0.00014684355,0.05682235,0.027957333,0.00022506318,0.8385957],"study_design_scores_gemma":[0.0029069977,0.0009513654,0.000060064627,0.021367026,0.00068659894,0.00005220858,0.005179121,0.00011922294,0.046837885,0.0009735384,0.917137,0.0037289618],"about_ca_topic_score_codex":0.00012865537,"about_ca_topic_score_gemma":0.0001721102,"teacher_disagreement_score":0.91691196,"about_ca_system_score_codex":0.000090397494,"about_ca_system_score_gemma":0.00010119982,"threshold_uncertainty_score":0.9999148},"labels":[],"label_agreement":null},{"id":"W208494508","doi":"10.1007/s00213-002-1273-1","title":"Dissociating anorexia and anhedonia elicited by interleukin-1β: antidepressant and gender effects on responding for \"free chow\" and \"earned\" sucrose intake","year":2003,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":127,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Royal Ottawa Mental Health Centre","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Anhedonia; Anorexia; Psychology; Antidepressant; Endocrinology; Internal medicine; Interleukin 1β; Interleukin; Developmental psychology; Psychotherapist; Medicine; Psychiatry; Anxiety; Pleasure; Cytokine","score_opus":0.024644307498567816,"score_gpt":0.3248231724026256,"score_spread":0.30017886490405776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W208494508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962854,0.0009473038,0.00007806743,0.0005308242,0.00054110563,0.00072290475,0.000047652757,0.00007827577,0.000768496],"genre_scores_gemma":[0.99448335,0.00046336677,0.00020130143,0.004408565,0.00006249893,0.00009130197,0.0000033193562,0.000043944307,0.00024235067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978963,0.00037975732,0.0002564735,0.0007955841,0.00013793935,0.0005339165],"domain_scores_gemma":[0.99779946,0.0016611895,0.00014310544,0.00018774763,0.000022048454,0.0001864504],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035212713,0.00027987175,0.0003090002,0.00022981474,0.00032539357,0.00009986338,0.00017843065,0.00014522484,0.000029434008],"category_scores_gemma":[0.0010935374,0.00026300803,0.00004243007,0.00027574736,0.00023883852,0.00014785117,0.00008781913,0.00027016984,0.0000030928963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076148636,0.00011588698,0.008834285,0.00013048145,0.000029778914,0.00001776673,0.00092559686,0.0000010512553,0.9736492,0.0017761694,0.006607965,0.0071503436],"study_design_scores_gemma":[0.03189771,0.0018234913,0.08543512,0.00010889001,0.00012430201,0.0001590806,0.00042992897,0.00090902136,0.8383349,0.011699216,0.02774743,0.0013308977],"about_ca_topic_score_codex":0.0000047317158,"about_ca_topic_score_gemma":0.000003962906,"teacher_disagreement_score":0.13531429,"about_ca_system_score_codex":0.000030499563,"about_ca_system_score_gemma":0.000014893876,"threshold_uncertainty_score":0.99998224},"labels":[],"label_agreement":null},{"id":"W2085179013","doi":"10.1016/j.jneuroim.2007.02.008","title":"Interferon-α effects are exaggerated when administered on a psychosocial stressor backdrop: Cytokine, corticosterone and brain monoamine variations","year":2007,"lang":"en","type":"article","venue":"Journal of Neuroimmunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa; Robarts Clinical Trials; Carleton University","funders":"","keywords":"Cytokine; Stressor; Norepinephrine; Corticosterone; Psychosocial; Alpha (finance); Monoamine neurotransmitter; Endocrinology; Immunotherapy; Distress; Alpha interferon; Internal medicine; Medicine; Dopamine; Psychology; Immunology; Interferon; Serotonin; Clinical psychology; Psychiatry; Immune system; Hormone; Receptor","score_opus":0.02832624516965723,"score_gpt":0.2881922653031006,"score_spread":0.2598660201334434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085179013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99247164,0.00013271901,0.00069543306,0.004912878,0.0011629993,0.00021128666,0.000013614325,0.00003306445,0.0003663689],"genre_scores_gemma":[0.9958234,0.00007192847,0.00012537927,0.0035737506,0.0001384847,0.000002838411,0.0000010789573,0.000030132986,0.00023302711],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99812984,0.0003500137,0.0006187474,0.00030482278,0.00022300972,0.00037353934],"domain_scores_gemma":[0.9971887,0.0016864524,0.0006937705,0.00022890493,0.00008392782,0.00011825632],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021264137,0.00022100014,0.00040069106,0.00035685385,0.00013745828,0.00007205971,0.00031486846,0.00014155287,0.000060435177],"category_scores_gemma":[0.002125269,0.00019499958,0.00009006897,0.00023539572,0.00019952196,0.00018454505,0.00007557213,0.0005595284,0.000019137879],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002008365,0.00052110205,0.00042599335,0.000020963953,0.00003811959,0.00052073825,0.000530944,0.0000030435979,0.9833094,0.0004110873,0.0017701394,0.010440106],"study_design_scores_gemma":[0.0074394117,0.010031198,0.8783337,0.0002728157,0.00004839367,0.0014770323,0.00024641858,0.000102117716,0.09471602,0.0011638091,0.005743665,0.00042540702],"about_ca_topic_score_codex":0.0000030154108,"about_ca_topic_score_gemma":0.000010407291,"teacher_disagreement_score":0.8885934,"about_ca_system_score_codex":0.000046154706,"about_ca_system_score_gemma":0.000043096206,"threshold_uncertainty_score":0.7951852},"labels":[],"label_agreement":null},{"id":"W2085247371","doi":"10.1016/j.jad.2011.12.041","title":"Serotonin transporter clustering in blood lymphocytes as a putative biomarker of therapeutic efficacy in major depressive disorder","year":2012,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Universidade de Santiago de Compostela","keywords":"Serotonin transporter; Biomarker; Major depressive disorder; Depression (economics); Psychology; Medicine; Serotonin; Psychiatry; Clinical psychology; Internal medicine; Biology; Genetics; Receptor; Mood","score_opus":0.016400453186162657,"score_gpt":0.2840255150559347,"score_spread":0.26762506186977203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085247371","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959615,0.0016320214,0.00064248947,0.00017355177,0.00018517063,0.00066833716,0.000008172156,0.000011882227,0.0007168877],"genre_scores_gemma":[0.99930185,0.00030959785,0.00007329527,0.00020866479,0.000020767911,0.000029733776,9.332317e-7,0.000040541297,0.0000145967515],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976763,0.00047065632,0.0006380609,0.00028076608,0.00039628742,0.0005379117],"domain_scores_gemma":[0.9982351,0.00092425314,0.00050825294,0.00015705558,0.000055763994,0.000119545584],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004247318,0.00029748306,0.00052208937,0.0006565762,0.000055131204,0.000021924976,0.00032579884,0.00012139719,0.000073176445],"category_scores_gemma":[0.00047806912,0.00024914794,0.00024351089,0.0009265759,0.0002520576,0.00067270966,0.000041968593,0.00033790563,0.0000054903753],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024613554,0.0064602103,0.5569212,0.00017111778,0.00023266267,0.00009550457,0.024806784,0.002106271,0.33493564,0.0002768187,0.000010042534,0.07152244],"study_design_scores_gemma":[0.013654627,0.000515476,0.83568984,0.00020854594,0.000057847694,0.000070439266,0.0031853304,0.0002130618,0.14517984,0.0008350834,0.00004973782,0.00034015908],"about_ca_topic_score_codex":0.00025801224,"about_ca_topic_score_gemma":0.00064579205,"teacher_disagreement_score":0.2787687,"about_ca_system_score_codex":0.00009202803,"about_ca_system_score_gemma":0.00011587483,"threshold_uncertainty_score":0.99999607},"labels":[],"label_agreement":null},{"id":"W2085498887","doi":"10.1016/s0920-9964(99)00116-4","title":"Immunosuppressive effects of clozapine and haloperidol: enhanced production of the interleukin-1 receptor antagonist","year":2000,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":147,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Clozapine; Haloperidol; Receptor antagonist; Interleukin 1 receptor antagonist; Antipsychotic; Proinflammatory cytokine; Cytokine; Antagonist; Pharmacology; Medicine; Interleukin; Internal medicine; Endocrinology; Receptor; Schizophrenia (object-oriented programming); Inflammation; Psychiatry; Dopamine","score_opus":0.021242700477961656,"score_gpt":0.2979152760944258,"score_spread":0.27667257561646413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085498887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99670947,0.00047411013,0.0000019225108,0.00075597747,0.0003806953,0.0006562133,0.000009737709,0.000021342745,0.0009905373],"genre_scores_gemma":[0.99641114,0.000901617,0.00009910157,0.00002654496,0.000075616896,0.00004104749,0.0000012558144,0.000018097928,0.0024255973],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978783,0.0005784401,0.00024943275,0.00041876695,0.00056373456,0.0003112965],"domain_scores_gemma":[0.9988838,0.00036058747,0.00007726403,0.0005145651,0.000108611035,0.00005520131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003411983,0.0001239267,0.00019828005,0.00012426484,0.00024369246,0.000034882003,0.0005020693,0.00006452211,0.00024965272],"category_scores_gemma":[0.0015249094,0.000085138854,0.000065492306,0.0007257488,0.0012268132,0.00014072913,0.00018185159,0.00038444446,0.00003356355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014005973,0.0001076146,0.000020336467,0.00015144658,0.000006299733,0.0000010854966,0.000596301,0.000003084988,0.94717205,0.00038337905,0.00063160335,0.04952622],"study_design_scores_gemma":[0.0011026935,0.00021976704,0.003364525,0.00018737392,0.000002534398,0.000005964619,0.000082672115,0.000011938333,0.99299854,0.000529989,0.0014112282,0.000082793405],"about_ca_topic_score_codex":0.000047551097,"about_ca_topic_score_gemma":0.000013887219,"teacher_disagreement_score":0.049443424,"about_ca_system_score_codex":0.000024352197,"about_ca_system_score_gemma":0.00010314591,"threshold_uncertainty_score":0.4520244},"labels":[],"label_agreement":null},{"id":"W2086673145","doi":"10.1097/tp.0b013e3181fed001","title":"Regulatory T-Cell Generation and Kidney Allograft Tolerance Induced by Mesenchymal Stem Cells Associated With Indoleamine 2,3-Dioxygenase Expression","year":2010,"lang":"en","type":"article","venue":"Transplantation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":353,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Mesenchymal stem cell; FOXP3; Immune tolerance; IL-2 receptor; Immunology; Immunosuppression; Medicine; Kidney; In vivo; Transplantation; Spleen; Kynurenine; Regulatory T cell; T cell; Cancer research; Immune system; Biology; Endocrinology; Internal medicine; Pathology","score_opus":0.01473205923068548,"score_gpt":0.21342613383173922,"score_spread":0.19869407460105373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086673145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99829334,0.000019484898,0.00064712006,0.00007022088,0.00017156139,0.00030826352,0.00012057828,0.00010277762,0.00026667965],"genre_scores_gemma":[0.99889314,0.000059390128,0.00016570816,0.00045220047,0.000045254194,0.00002314905,0.00010756382,0.000024308943,0.000229292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998768,0.00012019194,0.00018984283,0.00041268874,0.0002905692,0.00021872025],"domain_scores_gemma":[0.9994696,0.00008209946,0.000115625524,0.00015351406,0.000029624583,0.00014958673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117566706,0.0001800775,0.00013591402,0.000070059126,0.00016853622,0.000058669913,0.00010532219,0.00014918622,0.000029529909],"category_scores_gemma":[0.000016058464,0.00015556741,0.00002404734,0.00017476751,0.00007557638,0.0003153458,0.0000057764682,0.00023290329,0.000005349342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009884721,0.00010286319,0.00020983965,0.00003443033,0.0000023362354,0.000008586592,0.00061818823,0.000024319417,0.99813235,0.000028054623,0.00033815473,0.00040204098],"study_design_scores_gemma":[0.0020862338,0.00010794673,0.0035574725,0.000038090984,0.000007700488,0.0000072957273,0.000027300966,0.00092589913,0.9928824,0.0000060516977,0.00014206086,0.00021160331],"about_ca_topic_score_codex":0.000008868597,"about_ca_topic_score_gemma":0.00006868973,"teacher_disagreement_score":0.0052499953,"about_ca_system_score_codex":0.000011105197,"about_ca_system_score_gemma":0.00004294173,"threshold_uncertainty_score":0.63438547},"labels":[],"label_agreement":null},{"id":"W2086761335","doi":"10.1111/jnc.12792","title":"Desvenlafaxine prevents white matter injury and improves the decreased phosphorylation of the rate‐limiting enzyme of cholesterol synthesis in a chronic mouse model of depression","year":2014,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Saskatchewan; University of Alberta","funders":"Canadian Institutes of Health Research; AstraZeneca Canada","keywords":"Limiting; Depression (economics); White matter; Enzyme; Internal medicine; Phosphorylation; Endocrinology; Medicine; Cholesterol; Chemistry; Biochemistry","score_opus":0.011557698913703878,"score_gpt":0.2295273256134559,"score_spread":0.21796962669975203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086761335","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99948865,0.000052358366,0.00013765064,0.00013697206,0.000020439487,0.00009020183,0.0000072373687,0.000002035553,0.000064472675],"genre_scores_gemma":[0.9996963,0.000041043222,0.000041659376,0.00014552988,0.000018535415,0.000002847187,1.05175204e-7,0.000012419316,0.000041549883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887985,0.00015037956,0.00048771861,0.00013553498,0.00022987157,0.00011664158],"domain_scores_gemma":[0.9985543,0.00030183737,0.00083249755,0.00022821197,0.000045754266,0.00003740804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002834311,0.0001066625,0.00020807583,0.00004266132,0.000035369394,0.000011206412,0.00033437143,0.000054651675,0.0000075896864],"category_scores_gemma":[0.0007669894,0.000065647764,0.000089507055,0.00011369774,0.00013025236,0.00011325354,0.000085511434,0.00020403365,1.11151714e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001198164,0.00007143496,0.007312273,0.00015856074,0.000003549791,2.5037028e-7,0.000109820525,0.0012096579,0.9901921,8.334034e-7,0.000020477855,0.00080118177],"study_design_scores_gemma":[0.00046176868,0.000038413178,0.06558147,0.000256889,0.000014705443,0.0000100906145,0.00002879777,0.008288361,0.925203,0.000066488275,0.0000018476871,0.000048129423],"about_ca_topic_score_codex":0.0000025650168,"about_ca_topic_score_gemma":8.9011394e-7,"teacher_disagreement_score":0.064989105,"about_ca_system_score_codex":0.000019087016,"about_ca_system_score_gemma":0.00006701704,"threshold_uncertainty_score":0.26770383},"labels":[],"label_agreement":null},{"id":"W2087973865","doi":"10.1016/j.pneurobio.2008.01.004","title":"Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders","year":2008,"lang":"en","type":"review","venue":"Progress in Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":339,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; University of Ottawa; Carleton University","funders":"","keywords":"Neuroscience; Neurochemical; Neurotransmitter; Psychology; Neuropeptide; Neurotransmitter Agents; Vasopressin; Medicine; Internal medicine; Central nervous system; Receptor","score_opus":0.04229864824026432,"score_gpt":0.3206299657203129,"score_spread":0.2783313174800486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087973865","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18686378,0.8098294,0.000034632485,0.00024158819,0.00017040603,0.002576925,0.00012012523,0.00009603316,0.00006710186],"genre_scores_gemma":[0.09327762,0.90558964,0.00006395485,0.00021697463,0.00005695864,0.00063365296,0.00005822688,0.00008919338,0.000013790388],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950633,0.0013408255,0.0008536375,0.0018812187,0.00017817505,0.00068284426],"domain_scores_gemma":[0.9975836,0.0014525678,0.00038139103,0.00038662727,0.000026855174,0.00016894857],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010871664,0.0007561596,0.0015246087,0.00070584926,0.0001993801,0.000062471554,0.0005058281,0.000429615,0.00000435164],"category_scores_gemma":[0.00081927737,0.00064627745,0.00010037771,0.0011157206,0.0006770473,0.00023980426,0.00046048767,0.001029362,0.0000064321666],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006522882,0.00023509277,0.09892569,0.0036691867,0.0000096982385,0.0001115486,0.00050655036,0.000024492841,0.000046282996,0.000027656739,0.000051500494,0.8963271],"study_design_scores_gemma":[0.0044918656,0.0013232137,0.18048052,0.008357444,0.00015815451,0.00062523043,0.00003209658,0.00008299547,0.0006776573,0.00047459715,0.8003046,0.0029916423],"about_ca_topic_score_codex":0.000026002,"about_ca_topic_score_gemma":0.00026960715,"teacher_disagreement_score":0.89333546,"about_ca_system_score_codex":0.000030520354,"about_ca_system_score_gemma":0.00011479217,"threshold_uncertainty_score":0.99959886},"labels":[],"label_agreement":null},{"id":"W2088243327","doi":"10.3389/fnbeh.2014.00168","title":"Heightened fear in response to a safety cue and extinguished fear cue in a rat model of maternal immune activation","year":2014,"lang":"en","type":"article","venue":"Frontiers in Behavioral Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Fear conditioning; Extinction (optical mineralogy); Offspring; Psychology; Neuroscience; Recall; Developmental psychology; Forgetting; Amygdala; Classical conditioning; Freezing behavior; Immune system; Conditioning; Audiology; Pregnancy; Cognitive psychology; Medicine; Immunology; Biology","score_opus":0.02508585910579145,"score_gpt":0.2747688458601316,"score_spread":0.24968298675434017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088243327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99600047,0.000009493508,0.0026023348,0.00033905747,0.0004913478,0.00046936702,0.000011633861,0.000028693297,0.00004762727],"genre_scores_gemma":[0.9964449,0.000022846285,0.002889325,0.0004432001,0.0000073313663,0.000028069337,5.6188986e-7,0.000020462337,0.00014329949],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974239,0.00042974736,0.0005018922,0.00074964867,0.0004029872,0.0004918619],"domain_scores_gemma":[0.9993107,0.000083115614,0.0001338312,0.0003363629,0.000022020964,0.000114011666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000749027,0.000210587,0.00034209047,0.0007043429,0.00008430458,0.00006610101,0.0005295431,0.000088930115,0.0000032672463],"category_scores_gemma":[0.0010942768,0.00021430143,0.000039947266,0.001232434,0.00030636633,0.0004504192,0.00019510165,0.0002777159,0.0000012775498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012308379,0.00018637025,0.038597044,0.0000090285375,6.067979e-8,0.000013451131,0.0007720764,0.0031450028,0.9530576,0.000054004093,0.00002221887,0.0029123444],"study_design_scores_gemma":[0.0019933204,0.00034558412,0.42437968,0.00010804491,0.0000018892543,0.000007620319,0.00017131133,0.06846769,0.50359863,0.00048151895,0.000121975434,0.00032272082],"about_ca_topic_score_codex":0.00015684018,"about_ca_topic_score_gemma":0.000047485,"teacher_disagreement_score":0.44945893,"about_ca_system_score_codex":0.000107317675,"about_ca_system_score_gemma":0.00007583499,"threshold_uncertainty_score":0.8738959},"labels":[],"label_agreement":null},{"id":"W2089690473","doi":"10.1159/000229842","title":"Role of Norepinephrine and 5-Hydroxytryptamine in the Delayed Phase of the Inflammatory Reaction in Rats","year":2009,"lang":"en","type":"article","venue":"International Archives of Allergy and Applied Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Norepinephrine; Immunology; Medicine; Serotonin; Inflammation; Internal medicine; Dopamine; Receptor","score_opus":0.007381303809199189,"score_gpt":0.2339982008563633,"score_spread":0.22661689704716412,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089690473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99434054,0.00012550576,0.000011332331,0.0004889102,0.000023996361,0.00009912783,0.000004839452,0.0000025368308,0.0049031833],"genre_scores_gemma":[0.9994419,0.00038459804,0.000030555366,0.00011496327,0.0000068487307,0.0000055483374,0.0000025510267,0.0000021275657,0.00001085713],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946254,0.000049409944,0.00022752045,0.00011515122,0.000075572745,0.000069811154],"domain_scores_gemma":[0.99957186,0.00018975232,0.00012946023,0.00009750349,0.0000055740525,0.000005835822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004891895,0.00006050447,0.00010307161,0.00011356457,0.00001656897,0.0000021946305,0.00022253492,0.000026393505,0.000004753243],"category_scores_gemma":[0.000047384703,0.000040994466,0.000021240756,0.00007649622,0.00029534142,0.000032804204,0.00005617817,0.00010790141,1.3426951e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045742857,0.00019656194,0.00010104899,0.000001975705,0.000012910338,6.093153e-7,0.0011345479,0.000042793905,0.92805433,0.044169422,0.0000012903247,0.025827054],"study_design_scores_gemma":[0.0018930204,0.00015455367,0.4248874,0.000023189219,0.0000012376096,0.000012364739,0.0004596868,0.00053398527,0.5426185,0.02888733,0.00047583165,0.000052906038],"about_ca_topic_score_codex":0.000032626616,"about_ca_topic_score_gemma":0.000058878242,"teacher_disagreement_score":0.42478633,"about_ca_system_score_codex":0.0000024904962,"about_ca_system_score_gemma":0.000009733587,"threshold_uncertainty_score":0.16717058},"labels":[],"label_agreement":null},{"id":"W2091527091","doi":"10.1016/j.psychres.2004.06.023","title":"Genetic association analysis of the glutathione peroxidase (GPX1) gene polymorphism (Pro197Leu) with tardive dyskinesia","year":2006,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Tardive dyskinesia; GPX1; Oxidative stress; Glutathione peroxidase; Genotype; Dyskinesia; Gene polymorphism; Polymorphism (computer science); Neurotoxicity; Internal medicine; Endocrinology; Genetics; Medicine; Biology; Gene; Schizophrenia (object-oriented programming); Toxicity; Superoxide dismutase; Psychiatry","score_opus":0.023471963337946922,"score_gpt":0.2895659616341402,"score_spread":0.2660939982961933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091527091","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917504,0.00028473916,0.00013063887,0.003981323,0.00017959984,0.0003920854,0.00006471866,0.000035805468,0.0031806808],"genre_scores_gemma":[0.99653995,0.000027489206,0.00054694514,0.00022283349,0.00015453769,0.000036872705,0.0000066069842,0.000023045488,0.0024417252],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9964208,0.0006026159,0.00030888405,0.00051447324,0.0015910624,0.0005621495],"domain_scores_gemma":[0.9986641,0.00027467674,0.0001863071,0.00059907144,0.00019800426,0.0000778799],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005911143,0.00015636817,0.0002517175,0.0005528517,0.00048276814,0.00009038248,0.00059247686,0.000104020684,0.00019493068],"category_scores_gemma":[0.0002459844,0.00010520793,0.0002073888,0.005631264,0.00025847575,0.00008683905,0.00011146997,0.0003707498,0.000039699233],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020604994,0.0007611662,0.70750546,0.00004391759,0.00025398016,0.000008421825,0.00025945678,0.0014236174,0.27843648,0.0025146948,0.008123233,0.00046347847],"study_design_scores_gemma":[0.0008482576,0.00013798024,0.9655806,0.000016303931,0.0001599062,0.0000043265495,0.00014426335,0.00090947584,0.029757543,0.0018475297,0.0004074773,0.00018635365],"about_ca_topic_score_codex":0.00066972594,"about_ca_topic_score_gemma":0.00076348137,"teacher_disagreement_score":0.2580751,"about_ca_system_score_codex":0.000113065864,"about_ca_system_score_gemma":0.00023105176,"threshold_uncertainty_score":0.4290255},"labels":[],"label_agreement":null},{"id":"W2092302975","doi":"10.1016/j.neuroscience.2014.04.061","title":"Preventive effect of α-lipoic acid on prepulse inhibition deficits in a juvenile two-hit model of schizophrenia","year":2014,"lang":"en","type":"article","venue":"Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"","keywords":"Prepulse inhibition; Oxidative stress; Prefrontal cortex; Schizophrenia (object-oriented programming); Lipoic acid; Neuroscience; Psychology; Offspring; Maternal deprivation; Medicine; Internal medicine; Psychiatry; Antioxidant; Pregnancy; Cognition; Chemistry; Biology; Biochemistry","score_opus":0.01735607128828631,"score_gpt":0.26170511923390744,"score_spread":0.24434904794562112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092302975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99637914,0.000007770235,0.00086529367,0.00004175894,0.00018861449,0.00041107702,0.00001900694,0.00003908363,0.002048254],"genre_scores_gemma":[0.9994948,0.00000721227,0.00008220468,0.00026904594,0.000011883229,0.000028141456,5.533779e-7,0.000015136919,0.000091023125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99778426,0.00038326526,0.00035748509,0.0006381228,0.0005179677,0.0003188937],"domain_scores_gemma":[0.99894863,0.0003490358,0.0002318733,0.00037667638,0.00002392204,0.00006987054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042985298,0.00018648761,0.00029801912,0.0002655861,0.00007202867,0.000020747382,0.0003802355,0.00005322346,0.000009708012],"category_scores_gemma":[0.002271187,0.00016312991,0.00009257119,0.0008746883,0.00036331217,0.0002592486,0.000114629416,0.0001913036,0.000010282546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003154533,0.00018635126,0.0004475953,0.0000532307,1.875489e-7,0.0000021165963,0.00014244305,0.010199811,0.9830856,0.0019500747,0.000010881232,0.0036063066],"study_design_scores_gemma":[0.0014292572,0.0009496947,0.0048322426,0.00010086647,0.0000031590257,0.0000034793359,0.0000035429082,0.056978803,0.9341996,0.0013610859,0.000009567449,0.00012870143],"about_ca_topic_score_codex":0.000010063907,"about_ca_topic_score_gemma":0.000012884481,"teacher_disagreement_score":0.04888595,"about_ca_system_score_codex":0.000022183543,"about_ca_system_score_gemma":0.00005449286,"threshold_uncertainty_score":0.66522443},"labels":[],"label_agreement":null},{"id":"W2092608768","doi":"10.1016/j.jad.2014.03.023","title":"C-reactive protein, interleukin-6, soluble tumor necrosis factor α receptor 2 and incident clinical depression","year":2014,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Cancer Institute; National Institutes of Health","keywords":"Depression (economics); Medicine; Internal medicine; Prospective cohort study; Antidepressant; C-reactive protein; Tumor necrosis factor alpha; Body mass index; Cross-sectional study; Menopause; Inflammation; Pathology","score_opus":0.018399890803840985,"score_gpt":0.2962633378755576,"score_spread":0.2778634470717166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092608768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99577177,0.00008016324,0.0016561775,0.00041647922,0.0007381539,0.00045698497,0.000005251246,0.00003159189,0.0008434383],"genre_scores_gemma":[0.9988332,0.000053435488,0.00026015338,0.00056502956,0.00014567868,0.00001529416,4.833471e-7,0.00003437486,0.00009239801],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99755245,0.00069103943,0.0005687534,0.0004258651,0.0004266607,0.00033523765],"domain_scores_gemma":[0.9976309,0.001039601,0.00075700507,0.00019671532,0.00012821067,0.00024758364],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005782097,0.0002595076,0.00046226685,0.00020430869,0.00017989444,0.000105296866,0.00033143113,0.000109085304,0.00008170961],"category_scores_gemma":[0.004926857,0.00020026114,0.00025858887,0.00024347134,0.00033546248,0.00058379764,0.0001439743,0.0006238408,0.00002302007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016049518,0.0012992736,0.12836084,0.0000779834,0.00009308135,0.000015700347,0.0020658104,0.000017692248,0.6940091,0.00040315406,0.0033352573,0.16871715],"study_design_scores_gemma":[0.008750065,0.0046240073,0.4334144,0.0004693365,0.000056052577,0.00010116919,0.0016528609,0.00045573854,0.52947867,0.0068669724,0.0132229235,0.000907784],"about_ca_topic_score_codex":0.00004384202,"about_ca_topic_score_gemma":0.00007364813,"teacher_disagreement_score":0.30505356,"about_ca_system_score_codex":0.000076668475,"about_ca_system_score_gemma":0.00008071911,"threshold_uncertainty_score":0.8166412},"labels":[],"label_agreement":null},{"id":"W2092669597","doi":"10.1016/j.pnpbp.2007.09.015","title":"Pro-inflammatory cytokines and treatment response to escitaloprsam in major depressive disorder","year":2007,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":288,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Eesti Teadusfondi","keywords":"Escitalopram; Major depressive disorder; Depression (economics); Antidepressant; Internal medicine; Cytokine; Rating scale; Tumor necrosis factor alpha; Medicine; Proinflammatory cytokine; Interleukin; Pathophysiology; Psychology; Oncology; Inflammation; Amygdala","score_opus":0.022685865135695378,"score_gpt":0.32420628191914286,"score_spread":0.3015204167834475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092669597","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897977,0.0023854175,0.000010817205,0.005258136,0.00093388924,0.0013329939,0.000015451977,0.00010416687,0.0001614201],"genre_scores_gemma":[0.99430037,0.00055184466,0.00031038735,0.0043876944,0.00011874033,0.0002738566,0.0000016767159,0.000021399832,0.000034024557],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99705786,0.0004912808,0.00049123884,0.0011035007,0.00012917341,0.00072697696],"domain_scores_gemma":[0.9985787,0.00085278926,0.00010926557,0.00019023808,0.000015644373,0.00025335222],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046294913,0.00037695406,0.00036280655,0.00040991613,0.00016659076,0.00003825667,0.000274995,0.00028071794,0.000045756962],"category_scores_gemma":[0.00024672103,0.00027564718,0.000058663307,0.0005713862,0.0006645737,0.000110627014,0.00015010219,0.0003757214,0.0000133880585],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01339937,0.00082599104,0.9410131,0.00002058229,0.000007749409,0.00026147612,0.00020240703,0.0000029944347,0.014672432,0.00032270004,0.00009920989,0.029171987],"study_design_scores_gemma":[0.0074023763,0.0012097764,0.98453796,0.000025463218,0.0000066575312,0.00006245334,0.00009327219,0.000024590632,0.001181976,0.0011155694,0.0039992076,0.0003406772],"about_ca_topic_score_codex":0.000003722565,"about_ca_topic_score_gemma":0.00012825213,"teacher_disagreement_score":0.04352488,"about_ca_system_score_codex":0.000030844145,"about_ca_system_score_gemma":0.00004092734,"threshold_uncertainty_score":0.99996954},"labels":[],"label_agreement":null},{"id":"W2092805551","doi":"10.1177/2167702612455743","title":"Targeted Rejection Triggers Differential Pro- and Anti-Inflammatory Gene Expression in Adolescents as a Function of Social Status","year":2012,"lang":"en","type":"article","venue":"Clinical Psychological Science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Inflammation; Gene expression; Psychology; Depression (economics); Messenger RNA; Signal transduction; Social defeat; Immunology; Gene; Medicine; Biology; Genetics; Neuroscience","score_opus":0.07605774171591832,"score_gpt":0.3922613413308704,"score_spread":0.31620359961495204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092805551","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975331,0.000039352704,0.00018678373,0.000067656205,0.0010657999,0.00029756784,0.0000024932342,0.000051032388,0.0007562197],"genre_scores_gemma":[0.9993419,0.000066288834,0.00006515605,0.00035504097,0.00013400437,0.000009681853,7.125628e-7,0.000006070278,0.00002111291],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99750865,0.00027518574,0.0005360211,0.0006570107,0.0004588594,0.0005642631],"domain_scores_gemma":[0.9991884,0.00012959143,0.00021474659,0.00017209812,0.000030719228,0.0002644135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009316348,0.00013620892,0.00024567693,0.00012585569,0.00020211103,0.00003164318,0.0002596812,0.00019200209,0.00009117215],"category_scores_gemma":[0.0018942315,0.000099982564,0.000082292325,0.0006775941,0.001644647,0.00038006977,0.00012614348,0.00030750452,0.000022042228],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004600992,0.0010566184,0.10894143,0.000011172607,6.4652306e-7,0.0000018514587,0.000121322846,6.3017995e-7,0.8708779,0.00020690224,0.00007541736,0.018245988],"study_design_scores_gemma":[0.0013040085,0.00028162613,0.9506897,0.000024675024,0.0000027634653,0.0000024246851,0.00005696296,0.000023854163,0.046984605,0.00036376284,0.00013880846,0.00012685561],"about_ca_topic_score_codex":0.0000020716873,"about_ca_topic_score_gemma":7.5399197e-7,"teacher_disagreement_score":0.84174824,"about_ca_system_score_codex":0.000030074823,"about_ca_system_score_gemma":0.00003240149,"threshold_uncertainty_score":0.60597706},"labels":[],"label_agreement":null},{"id":"W2094141300","doi":"10.1007/s11920-013-0425-9","title":"Toward Clinically Applicable Biomarkers in Bipolar Disorder: Focus on BDNF, Inflammatory Markers, and Endothelial Function","year":2013,"lang":"en","type":"review","venue":"Current Psychiatry Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Mental Health","keywords":"Biomarker; Mood disorders; Medicine; Mood; Bipolar disorder; Population; Precision medicine; Bioinformatics; Clinical psychology; Psychiatry; Pathology; Anxiety; Biology","score_opus":0.046120897867108226,"score_gpt":0.317863897953057,"score_spread":0.27174300008594876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094141300","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007442607,0.9864157,0.00006852633,0.000110751695,0.008305364,0.002902555,0.00004324369,0.00020299976,0.0012066303],"genre_scores_gemma":[0.00029529838,0.998076,0.00007328515,0.000106599015,0.0004900879,0.0006480142,0.00004724637,0.00012982661,0.00013364687],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9939395,0.00048308668,0.0022574412,0.0019846666,0.00059426884,0.00074101647],"domain_scores_gemma":[0.99668044,0.00036363574,0.0015326446,0.001075678,0.00002757977,0.0003199938],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007188347,0.00090467336,0.0015374229,0.00060315843,0.00017006072,0.00016028488,0.0004024275,0.0005591331,0.00016828775],"category_scores_gemma":[0.0003536703,0.0007606375,0.00064395636,0.0006946081,0.000283762,0.00023791446,0.0002113482,0.0011434156,0.00018809253],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007384539,0.0004457324,0.0026373898,0.005932695,0.000052498523,0.000043931483,0.000012997149,5.141928e-7,0.000007968244,0.0004928365,0.004321612,0.985978],"study_design_scores_gemma":[0.0005575238,0.00020945109,0.00031911465,0.0042670113,0.00013981605,0.00018899016,0.000024244266,0.000008182351,0.000002570609,0.0016786207,0.991815,0.0007895281],"about_ca_topic_score_codex":0.000026025904,"about_ca_topic_score_gemma":0.000020722702,"teacher_disagreement_score":0.98749334,"about_ca_system_score_codex":0.00009661214,"about_ca_system_score_gemma":0.00060333987,"threshold_uncertainty_score":0.9994845},"labels":[],"label_agreement":null},{"id":"W2094296088","doi":"10.4236/ojpsych.2014.42018","title":"The Relationship between Impaired Methylnicotinate Response and Oxidative Stress in Schizophrenia","year":2014,"lang":"en","type":"article","venue":"Open Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NOSM University; Lakehead University","funders":"","keywords":"Schizophrenia (object-oriented programming); Lipid peroxidation; Oxidative stress; Arachidonic acid; Internal medicine; Vitamin E; Antioxidant; Endocrinology; Chemistry; Psychology; Biochemistry; Medicine; Psychiatry; Enzyme","score_opus":0.04161860752131329,"score_gpt":0.32073691604237015,"score_spread":0.27911830852105685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094296088","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98974967,0.0002202369,0.000118481854,0.008820352,0.00033664075,0.00015559609,0.000005850132,0.000004580236,0.00058859977],"genre_scores_gemma":[0.99799865,0.000021212209,0.001526967,0.00020824056,0.00009270957,0.0000021443755,2.1625223e-7,0.000011836646,0.00013804053],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99767864,0.0013477291,0.00041710612,0.00016735116,0.00020466607,0.00018450715],"domain_scores_gemma":[0.99594265,0.0033450245,0.00038712833,0.0001952687,0.000029461655,0.000100493075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022375323,0.00010400492,0.00018735169,0.00012856688,0.00028088476,0.00023395068,0.00072293024,0.00005175218,0.000010217808],"category_scores_gemma":[0.0034666208,0.0000708924,0.00005215515,0.00031496666,0.00017652163,0.0003906004,0.00012604643,0.000407356,0.000007783876],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0056386795,0.00017812687,0.9096736,0.000019624718,0.000022722752,0.000007631954,0.0010024878,0.000026352222,0.013002322,0.055306498,0.0015603765,0.013561611],"study_design_scores_gemma":[0.0024192382,0.00033140645,0.9300095,0.00011765319,0.00000873229,0.000022426526,0.0005578018,0.000017854227,0.004665922,0.061060876,0.00067463855,0.00011394333],"about_ca_topic_score_codex":0.0000068143036,"about_ca_topic_score_gemma":0.000072990755,"teacher_disagreement_score":0.020335943,"about_ca_system_score_codex":0.000016940585,"about_ca_system_score_gemma":0.00015506728,"threshold_uncertainty_score":0.4150119},"labels":[],"label_agreement":null},{"id":"W2095102348","doi":"10.1212/01.wnl.0000052682.99812.f5","title":"α-[ <sup>11</sup> C] methyl- <scp>L</scp> -tryptophan and glucose metabolism in patients with temporal lobe epilepsy","year":2003,"lang":"en","type":"article","venue":"Neurology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Epilepsy; Tryptophan; Temporal lobe; Metabolism; Carbohydrate metabolism; Chemistry; Medicine; Biochemistry; Neuroscience; Biology; Amino acid","score_opus":0.010303226862359516,"score_gpt":0.21834181822080242,"score_spread":0.2080385913584429,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095102348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99636626,0.00021820069,0.00003450099,0.00024203405,0.00022172903,0.00047227164,0.000018324878,0.000096579395,0.0023300753],"genre_scores_gemma":[0.9933953,0.00004861105,0.00020518492,0.006101014,0.000035114746,0.00003535927,0.000005716042,0.000053668515,0.00011998334],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99686134,0.00074577343,0.00034945807,0.00094840606,0.0003256782,0.0007693679],"domain_scores_gemma":[0.9985561,0.00062480423,0.00013884122,0.00043520433,0.000037238606,0.00020780836],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019695912,0.00035955108,0.0004558582,0.0002996376,0.00012987082,0.000051307852,0.00032455425,0.00021882799,0.00005566428],"category_scores_gemma":[0.0012333533,0.0003082513,0.000060875354,0.0006272716,0.00039138278,0.0002557277,0.00010069593,0.00047033056,0.00005400137],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051158166,0.0015405595,0.9592829,0.000054773536,0.000025213,0.00037223054,0.001781261,0.00042804214,0.012241954,0.018809916,0.001534582,0.0034170004],"study_design_scores_gemma":[0.009574852,0.0017997198,0.8545743,0.000008385482,0.000024590192,0.000075812466,0.000094456605,0.00027173516,0.032723647,0.0033894188,0.09711658,0.0003464895],"about_ca_topic_score_codex":0.000059948088,"about_ca_topic_score_gemma":0.000088927234,"teacher_disagreement_score":0.104708575,"about_ca_system_score_codex":0.000009989222,"about_ca_system_score_gemma":0.00005828685,"threshold_uncertainty_score":0.99993694},"labels":[],"label_agreement":null},{"id":"W2096662368","doi":"10.1002/ajmg.b.31204","title":"A follow‐up case–control association study of tractable (druggable) genes in recurrent major depression","year":2011,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Major depressive disorder; Depression (economics); Internal medicine; SNP; Single-nucleotide polymorphism; Candidate gene; Oncology; Genetics; Biology; Medicine; Psychology; Psychiatry; Genotype; Gene; Mood","score_opus":0.026306848408258785,"score_gpt":0.2783841291272932,"score_spread":0.2520772807190344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096662368","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99424267,0.0024718705,0.00037222568,0.00020948781,0.0020654493,0.0004317109,0.00001388555,0.000014984997,0.00017770476],"genre_scores_gemma":[0.99523187,0.0033562707,0.0006902126,0.00041860822,0.00021836086,0.000010140542,2.9248986e-7,0.000047845875,0.00002642912],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99395907,0.0012782636,0.0016254364,0.0004800029,0.0020704113,0.0005868241],"domain_scores_gemma":[0.9965058,0.00059527514,0.0018001978,0.00041627925,0.00019871398,0.00048374175],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011969173,0.000314237,0.0007369991,0.0004826076,0.000101953534,0.00003049684,0.00088234927,0.00012255069,0.00013782273],"category_scores_gemma":[0.001166123,0.0002727843,0.00021052039,0.0013539467,0.0001737709,0.000057157868,0.000118407785,0.00070668827,0.0000071289637],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013690039,0.007961023,0.58021176,0.000070667906,0.00018814244,0.0028613303,0.006042208,0.0009270745,0.008632467,0.0000148273375,0.001641731,0.39007974],"study_design_scores_gemma":[0.06628143,0.05074588,0.80266464,0.00045924287,0.0018946137,0.007359241,0.02057903,0.009161978,0.028050076,0.0012067568,0.008603926,0.0029931946],"about_ca_topic_score_codex":0.000083843275,"about_ca_topic_score_gemma":0.00017801521,"teacher_disagreement_score":0.38708654,"about_ca_system_score_codex":0.000057824403,"about_ca_system_score_gemma":0.00033645506,"threshold_uncertainty_score":0.99997246},"labels":[],"label_agreement":null},{"id":"W2096883848","doi":"10.1186/1745-6215-15-390","title":"The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy – CTN PT006: study protocol for a randomized controlled trial","year":2014,"lang":"en","type":"article","venue":"Trials","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Collège de Maisonneuve; Ottawa Hospital; McGill University; McGill University Health Centre; Canadian Institutes of Health Research","funders":"McGill University Health Centre; Ottawa Hospital Research Institute; McGill University; Canadian Foundation for AIDS Research","keywords":"Medicine; Immune system; Niacin; Immunology; T cell; Randomized controlled trial; CD8; Internal medicine","score_opus":0.03214178216427306,"score_gpt":0.3273993967637366,"score_spread":0.29525761459946354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096883848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6435186,0.0000012341064,0.00003090832,0.00002222135,0.000026564034,0.3562518,0.000005075266,0.00002712245,0.000116462914],"genre_scores_gemma":[0.7318571,0.0000023073487,0.000004172311,0.00003600895,0.000033978784,0.26802537,0.0000039460647,0.00001573917,0.000021347108],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9939281,0.0042752507,0.00096507824,0.00033251688,0.00029910213,0.00019998668],"domain_scores_gemma":[0.9915442,0.0072523844,0.0008875882,0.00019735223,0.0000857561,0.000032760945],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0025345592,0.00021867901,0.0012817349,0.00015669239,0.00014758928,0.00007052828,0.000111842346,0.00005686228,0.000008764837],"category_scores_gemma":[0.011349228,0.00010942103,0.0001849509,0.00023397381,0.000115324656,0.00011735778,0.00001192769,0.000092939714,0.0000011394841],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.92399293,0.0019897071,0.00037119634,0.0000061769865,0.000030771353,1.4438601e-7,0.00013528857,0.00000413594,0.0601038,0.0001503294,0.0000042908378,0.0132112205],"study_design_scores_gemma":[0.89216644,0.008125797,0.0030808356,0.00003338781,0.00002853579,8.760046e-8,0.00004343917,0.0004990181,0.095407315,0.00047311428,0.000030678602,0.00011134307],"about_ca_topic_score_codex":0.00002969704,"about_ca_topic_score_gemma":0.0000049578475,"teacher_disagreement_score":0.088338524,"about_ca_system_score_codex":0.0000130783155,"about_ca_system_score_gemma":0.000036134064,"threshold_uncertainty_score":0.9969786},"labels":[],"label_agreement":null},{"id":"W2097181433","doi":"10.1038/tp.2013.73","title":"DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP","year":2013,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"H. Lundbeck A/S; European Commission; Medical Research Council; National Institute for Health and Care Research; Menzies Centre for Australian Studies, King's College London, University of London; GlaxoSmithKline","keywords":"Antidepressant; DNA methylation; Escitalopram; Nortriptyline; Major depressive disorder; CpG site; Epigenetics; Methylation; Medicine; Oncology; Pharmacology; Psychology; Bioinformatics; Clinical psychology; Internal medicine; Psychiatry; Biology; Genetics; Gene; Gene expression; Anxiety; Mood","score_opus":0.04721747153131118,"score_gpt":0.3380889343029776,"score_spread":0.2908714627716664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097181433","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868901,0.000056320718,0.00061108975,0.009951939,0.0007150876,0.00060865394,0.000019446567,0.00005814542,0.0010892426],"genre_scores_gemma":[0.99597377,0.000008295932,0.0016681503,0.0020820957,0.00009616562,0.000044025124,0.0000058602072,0.000020423913,0.00010120448],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99766856,0.0005143538,0.0006545826,0.00052311615,0.00034249257,0.0002969179],"domain_scores_gemma":[0.99897754,0.0005915001,0.00006676728,0.00022074429,0.00002113709,0.00012231542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061168405,0.00015498653,0.00019456807,0.0003768266,0.000041146766,0.000037501264,0.0002676009,0.00013330621,0.0003512517],"category_scores_gemma":[0.00034773105,0.00015598217,0.00008687558,0.00061237696,0.000066023946,0.00035980626,0.00002040972,0.0002525644,0.00027802482],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021952617,0.0010054642,0.8901359,0.000036337027,0.000007986643,0.0000104852115,0.0016263664,0.0017084742,0.084392436,0.0034955917,0.0032057595,0.012179952],"study_design_scores_gemma":[0.0019717498,0.00007278485,0.98447,0.000046126297,0.000001695685,0.0000027098683,0.000067801266,0.001300229,0.0013929214,0.009897752,0.0006032854,0.00017292163],"about_ca_topic_score_codex":0.000050848055,"about_ca_topic_score_gemma":0.00080466206,"teacher_disagreement_score":0.09433413,"about_ca_system_score_codex":0.000018443889,"about_ca_system_score_gemma":0.00013284758,"threshold_uncertainty_score":0.6360768},"labels":[],"label_agreement":null},{"id":"W2098120777","doi":"10.1503/jpn.120209","title":"Acute tryptophan depletion in humans: a review of theoretical, practical and ethical aspects","year":2013,"lang":"en","type":"review","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Serotonin; Tryptophan; Mood; Psychology; Medicine; Endocrinology; Psychiatry; Neuroscience; Internal medicine; Chemistry; Biochemistry; Amino acid","score_opus":0.05345112232327861,"score_gpt":0.3782636561252125,"score_spread":0.3248125338019339,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098120777","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00076612196,0.99413407,0.00008989635,0.0032064072,0.00085167924,0.0005175513,0.000012378473,0.000008701544,0.0004132074],"genre_scores_gemma":[0.00067988754,0.9954202,0.0007150194,0.0030499508,0.0000947588,0.000009193607,2.6199677e-7,0.000018913619,0.000011806648],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99631375,0.0009082089,0.0012800271,0.0005461168,0.00063335575,0.00031852734],"domain_scores_gemma":[0.99752337,0.00069324387,0.0012261047,0.0002631065,0.00005586872,0.00023829013],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010136929,0.00033710548,0.0013582197,0.00031281135,0.000108366025,0.00008104367,0.00047691472,0.00031784,0.000046768375],"category_scores_gemma":[0.00249029,0.00022959593,0.00028493546,0.0007757325,0.0013813062,0.00028028412,0.00013480653,0.0017218927,0.000003225175],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010784706,0.0010074851,0.000058031554,0.10386316,0.00002440748,0.00037823696,0.00018556442,2.9745863e-7,0.004245009,0.75731194,0.002123746,0.13069427],"study_design_scores_gemma":[0.0031259279,0.005897265,0.0006427553,0.35386598,0.001578285,0.022309767,0.00015818559,0.00007162527,0.00085891964,0.07689382,0.53239673,0.0022007306],"about_ca_topic_score_codex":7.499798e-7,"about_ca_topic_score_gemma":0.0000017678911,"teacher_disagreement_score":0.68041813,"about_ca_system_score_codex":0.000018918327,"about_ca_system_score_gemma":0.0006171476,"threshold_uncertainty_score":0.936265},"labels":[],"label_agreement":null},{"id":"W2098158682","doi":"10.1177/0269881113503506","title":"Prevention and reversal of ketamine-induced schizophrenia related behavior by minocycline in mice: Possible involvement of antioxidant and nitrergic pathways","year":2013,"lang":"en","type":"article","venue":"Journal of Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico","keywords":"Minocycline; TBARS; Prepulse inhibition; Ketamine; Pharmacology; Schizophrenia (object-oriented programming); Clozapine; Oxidative stress; Psychology; Medicine; Chemistry; Neuroscience; Internal medicine; Psychiatry; Lipid peroxidation; Biochemistry","score_opus":0.022225602886329212,"score_gpt":0.29733946708060505,"score_spread":0.27511386419427586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098158682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979721,0.0009470673,0.000005503179,0.00028473142,0.00037547763,0.00035250638,0.000009429959,0.0000048873712,0.000048315072],"genre_scores_gemma":[0.99838,0.0010625704,0.00031198986,0.00013356537,0.000022231574,0.000008554744,8.5457776e-7,0.000011184915,0.00006907264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99837554,0.00021662653,0.00083387666,0.00020477983,0.00018582006,0.00018334723],"domain_scores_gemma":[0.9988627,0.00011784743,0.00076285185,0.00007611548,0.000079091704,0.00010140138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027986217,0.00013574422,0.00035833623,0.00032400514,0.000028504995,0.000010055369,0.00015739269,0.00011197052,0.00015487835],"category_scores_gemma":[0.00006640132,0.000118944095,0.0000709684,0.00027574238,0.0001540927,0.00024388407,0.00004159531,0.00027456926,0.0000018132911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039738519,0.0007107482,0.0048236325,0.000050505416,0.000019058363,0.000021699228,0.00026253416,0.0000016947234,0.9885598,0.000022280963,0.0009436342,0.00418704],"study_design_scores_gemma":[0.013604952,0.0015020191,0.17339042,0.00011699632,0.00007930906,0.00014265251,0.0003338909,0.00012651006,0.8094643,0.0010345888,0.00004027023,0.00016412848],"about_ca_topic_score_codex":0.000032391246,"about_ca_topic_score_gemma":0.000008085117,"teacher_disagreement_score":0.17909552,"about_ca_system_score_codex":0.000020488602,"about_ca_system_score_gemma":0.000051863994,"threshold_uncertainty_score":0.48503992},"labels":[],"label_agreement":null},{"id":"W2098164623","doi":"10.1001/archgenpsychiatry.2010.22","title":"Mitochondrial Complex I Activity and Oxidative Damage to Mitochondrial Proteins in the Prefrontal Cortex of Patients With Bipolar Disorder","year":2010,"lang":"en","type":"article","venue":"Archives of General Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":446,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Bipolar disorder; Prefrontal cortex; Schizophrenia (object-oriented programming); Internal medicine; Oxidative stress; Oxidative phosphorylation; Mitochondrion; Major depressive disorder; Nitrotyrosine; Endocrinology; Mitochondrial respiratory chain; Psychiatry; Medicine; Psychology; Chemistry; Lithium (medication); Biochemistry; Nitric oxide synthase; Nitric oxide; Cognition","score_opus":0.00968680663500967,"score_gpt":0.24080071254879845,"score_spread":0.23111390591378878,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098164623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99678063,0.000014001114,0.00033094382,0.0004199358,0.00046952974,0.001252477,0.00018983167,0.000011745897,0.0005309265],"genre_scores_gemma":[0.9849332,0.0000035094304,0.014609808,0.00020824409,0.00014127689,0.000037649334,0.000011923563,0.000018341383,0.00003607147],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985999,0.00019555917,0.00023081897,0.00041556923,0.00030409585,0.0002540681],"domain_scores_gemma":[0.9992286,0.00014553577,0.00016098567,0.0003736184,0.000013887923,0.00007737447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003338686,0.00019454994,0.00023534236,0.00014207259,0.00010108921,0.000021958866,0.00043993443,0.000046871795,0.000022708035],"category_scores_gemma":[0.000085501,0.00013130862,0.000064487234,0.00023547627,0.0005003904,0.00014392259,0.00011449809,0.00029185897,0.0000014577736],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015063293,0.00086750515,0.04561309,0.000028302347,0.000009098764,4.3292832e-7,0.0015167407,0.000010435902,0.94636613,0.001343483,0.0001062834,0.002632156],"study_design_scores_gemma":[0.002724789,0.0009094676,0.9714699,0.000019766529,0.00000762216,9.975852e-7,0.00012795655,0.00011091386,0.022770254,0.0010022516,0.0006723529,0.00018374731],"about_ca_topic_score_codex":0.00025291528,"about_ca_topic_score_gemma":0.0032388808,"teacher_disagreement_score":0.92585677,"about_ca_system_score_codex":0.000002496155,"about_ca_system_score_gemma":0.00006681638,"threshold_uncertainty_score":0.535461},"labels":[],"label_agreement":null},{"id":"W2098731039","doi":"10.1186/1741-7015-10-66","title":"Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways","year":2012,"lang":"en","type":"review","venue":"BMC Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":633,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Cilag; National Institutes of Health; H. Lundbeck A/S; Beyond Blue; Sanofi; National Health and Medical Research Council; Servier; Pfizer; Geelong Region Medical Research Foundation; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Sickness behavior; Inflammation; Anhedonia; Depression (economics); Immunology; Anorexia; Atypical depression; Allostatic load; Bystander effect; Psychoneuroimmunology; Immune system; Cognition; Psychiatry; Internal medicine; Physiology","score_opus":0.15754932227039012,"score_gpt":0.35307867786613184,"score_spread":0.19552935559574172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098731039","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008012057,0.98879886,0.000025858402,0.00004690865,0.00069136824,0.0017813217,0.00010659398,0.00017341366,0.0003636093],"genre_scores_gemma":[0.0021014235,0.99460536,0.00009570857,0.000459451,0.00058371783,0.00062837335,0.000038972306,0.00011147624,0.0013755134],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99692124,0.0005598335,0.0006384108,0.00084547175,0.0005360672,0.0004989548],"domain_scores_gemma":[0.9971446,0.0011849727,0.0004069741,0.0007398613,0.00003628619,0.00048733907],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004094564,0.00055257836,0.0013745688,0.00039197181,0.0001644877,0.000034443656,0.0005166854,0.00031276353,0.00035397123],"category_scores_gemma":[0.002711668,0.00037227492,0.00014143654,0.00041441745,0.00023206073,0.00013840177,0.00030426282,0.00037491854,0.00021724682],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012701991,0.00012164362,0.0012442505,0.013104584,0.000008853056,0.00015550182,0.00070472434,1.0015268e-7,0.0022457037,0.000073173804,0.003029003,0.97918546],"study_design_scores_gemma":[0.0007354314,0.00009417119,0.0068532806,0.015171982,0.00031528718,0.00013704515,0.00015240592,7.6802223e-7,0.00021907286,0.000008934102,0.97577554,0.00053606945],"about_ca_topic_score_codex":0.0000062921354,"about_ca_topic_score_gemma":0.000018050296,"teacher_disagreement_score":0.9786494,"about_ca_system_score_codex":0.000053029613,"about_ca_system_score_gemma":0.00017458596,"threshold_uncertainty_score":0.9998729},"labels":[],"label_agreement":null},{"id":"W2099429097","doi":"10.1371/journal.pone.0099211","title":"Fludarabine Downregulates Indoleamine 2,3-Dioxygenase in Tumors via a Proteasome-Mediated Degradation Mechanism","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO; Centre hospitalier universitaire de Québec; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Fludarabine; Indoleamine 2,3-dioxygenase; Cancer research; STAT protein; STAT1; Proteasome inhibitor; Proteasome; Biology; Medicine; Immunology; Signal transduction; Interferon; Cell biology; Internal medicine; STAT3; Biochemistry; Cyclophosphamide","score_opus":0.028878476751333135,"score_gpt":0.20945187266310186,"score_spread":0.18057339591176874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099429097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975617,0.00001879502,0.00040414068,0.0005653408,0.000027885499,0.0007972669,0.000011869101,0.00020868031,0.00040430416],"genre_scores_gemma":[0.9979515,0.000013003855,0.0007591824,0.00059806707,0.000058050573,0.00013775405,0.000029410206,0.00003436169,0.00041865453],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981106,0.00024521808,0.00031442734,0.00048093835,0.00045626712,0.00039257915],"domain_scores_gemma":[0.9991737,0.0002324116,0.00011871089,0.000315421,0.000036937196,0.0001228412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028243914,0.00020748404,0.0002992234,0.00026461974,0.00009445946,0.000041864852,0.00026643707,0.00009190965,0.00016022015],"category_scores_gemma":[0.0018151017,0.00019513482,0.000041288444,0.00064547366,0.00007699229,0.00022949469,0.00006406356,0.00025600486,0.0003760557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058535843,0.0014319874,0.00014718126,0.00006235499,0.0000063310495,0.000008899989,0.000109407956,0.000006637722,0.9960112,0.0012229437,0.000015154877,0.00091936707],"study_design_scores_gemma":[0.0016718339,0.00018512615,0.005290132,0.00012065767,0.0000044965946,0.0000032051496,0.000025666763,0.009293377,0.9788886,0.0042527393,0.000021376309,0.00024280822],"about_ca_topic_score_codex":0.0000328484,"about_ca_topic_score_gemma":0.00005424767,"teacher_disagreement_score":0.017122617,"about_ca_system_score_codex":0.00004584398,"about_ca_system_score_gemma":0.0000290685,"threshold_uncertainty_score":0.79573673},"labels":[],"label_agreement":null},{"id":"W2101163595","doi":"10.1093/schbul/sbq098","title":"Neonatal Behavioral Changes in Rats With Gestational Exposure to Lipopolysaccharide: A Prenatal Infection Model for Developmental Neuropsychiatric Disorders","year":2010,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":136,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Offspring; Autism; Schizophrenia (object-oriented programming); Pregnancy; Gestation; Lipopolysaccharide; Medicine; Prenatal development; Fetus; Physiology; Psychology; Internal medicine; Psychiatry; Biology","score_opus":0.015196188294860424,"score_gpt":0.24958528750584835,"score_spread":0.23438909921098794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101163595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99374473,0.0000091450265,0.0016549691,0.0027896194,0.0004295098,0.0010464024,0.00011234677,0.00013844484,0.00007480998],"genre_scores_gemma":[0.98181665,0.000009442814,0.016626911,0.00062445545,0.000105225256,0.0004893315,0.000030422136,0.000058207414,0.00023935107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981537,0.000046559067,0.0002500737,0.00071666174,0.00035443934,0.00047858973],"domain_scores_gemma":[0.99941003,0.00010334597,0.000091431546,0.00018936665,0.00003844522,0.000167348],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012027851,0.00029774386,0.0001864219,0.00038430336,0.00022479767,0.00009785783,0.00027586566,0.000113960894,0.0001663499],"category_scores_gemma":[0.00016750146,0.0002796975,0.00006017104,0.0004131638,0.00010395756,0.00013028445,0.00008734648,0.00032837086,0.00007214552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012772691,0.00230953,0.023702204,0.0002202886,0.00002590358,0.00006281594,0.0056408662,0.0084735835,0.74234194,0.011369656,0.0044620372,0.1886185],"study_design_scores_gemma":[0.05788707,0.009946446,0.25252658,0.0004285597,0.00016354067,0.0008577724,0.0013856567,0.03896124,0.57920116,0.009527047,0.03972437,0.009390533],"about_ca_topic_score_codex":0.00009731454,"about_ca_topic_score_gemma":0.011604904,"teacher_disagreement_score":0.22882438,"about_ca_system_score_codex":0.00003440949,"about_ca_system_score_gemma":0.00018239368,"threshold_uncertainty_score":0.99996555},"labels":[],"label_agreement":null},{"id":"W2101857382","doi":"10.1002/ajmg.b.30885","title":"Tagging SNP association study of the IL‐1β gene (<i>IL1B</i>) and childhood‐onset mood disorders","year":2008,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University Health Network","funders":"National Institute of Mental Health","keywords":"Single-nucleotide polymorphism; Genetics; SNP; Genetic association; Haplotype; Mood disorders; Allele; Genotype; Biology; Candidate gene; Mood; Gene; Medicine; Psychiatry; Anxiety","score_opus":0.013154044011354149,"score_gpt":0.24987218658670982,"score_spread":0.23671814257535567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101857382","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99423784,0.0005851538,0.00011425624,0.0032781009,0.0012848816,0.0003416423,0.000019091536,0.000017220049,0.00012180376],"genre_scores_gemma":[0.9847814,0.012624781,0.00039775006,0.0018344382,0.00027738657,0.0000036773392,4.3850932e-7,0.00004857688,0.000031550633],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99448395,0.00090440136,0.0010962548,0.00043437132,0.0025866393,0.00049436366],"domain_scores_gemma":[0.9969139,0.00054487144,0.0015189014,0.0004817055,0.00012205459,0.00041854673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005793961,0.0003074736,0.000546669,0.00021494155,0.0003245852,0.000034013286,0.0011135398,0.00010236348,0.000026951038],"category_scores_gemma":[0.0013106354,0.00023527344,0.0002109117,0.0013013232,0.0006361852,0.00004468004,0.0002848361,0.0007498001,0.0000037434775],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015954932,0.0049649216,0.92504394,0.000034095105,0.00020268216,0.00006608831,0.0063498905,0.0024644402,0.0062893485,0.00002207583,0.0054339305,0.04896906],"study_design_scores_gemma":[0.003748111,0.0039998214,0.98173517,0.00003035853,0.00017107549,0.0005673928,0.0014755756,0.0005066156,0.0023757592,0.00016860195,0.004811694,0.00040983025],"about_ca_topic_score_codex":0.00001618735,"about_ca_topic_score_gemma":0.000030026013,"teacher_disagreement_score":0.056691244,"about_ca_system_score_codex":0.000032293065,"about_ca_system_score_gemma":0.00037865006,"threshold_uncertainty_score":0.9594173},"labels":[],"label_agreement":null},{"id":"W2102430753","doi":"10.1155/2016/7215684","title":"Acute Psychological Stress Modulates the Expression of Enzymes Involved in the Kynurenine Pathway throughout Corticolimbic Circuits in Adult Male Rats","year":2015,"lang":"en","type":"article","venue":"Neural Plasticity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Canadian Institutes of Health Research; University of Calgary; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Quinolinic acid; Kynurenine pathway; Kynurenine; Kynurenic acid; Amygdala; Prefrontal cortex; Hippocampus; Endocrinology; Neuroprotection; Internal medicine; Serotonin; Hypothalamus; Tryptophan hydroxylase; Corticosterone; Neuroscience; Biology; Chemistry; Tryptophan; Hormone; Medicine; Biochemistry; Amino acid; Cognition","score_opus":0.06360749596334786,"score_gpt":0.3046626727985731,"score_spread":0.24105517683522526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102430753","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983245,0.000045537832,0.000030280784,0.00051821955,0.00022407442,0.0004184244,0.000053053736,0.000032709326,0.0003531591],"genre_scores_gemma":[0.99891716,0.000017420316,0.000012552765,0.0009339318,0.00003955504,0.000037563055,0.0000043630566,0.000010707865,0.000026763131],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794364,0.00045657277,0.0003711089,0.0004099911,0.00045638482,0.00036229249],"domain_scores_gemma":[0.9986134,0.00084555487,0.00014809718,0.0002812526,0.00004344134,0.0000682254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014318322,0.00019798118,0.00025010185,0.00006314234,0.00007480875,0.00004768004,0.0006596487,0.00010829851,0.000026343854],"category_scores_gemma":[0.0013594134,0.00010377799,0.00006127487,0.00046672724,0.00032092744,0.00018843244,0.00010902545,0.00041510578,0.000009951742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037973357,0.0009191054,0.019347178,0.000021921298,0.0000029228008,0.00016828212,0.0028632225,0.002302938,0.9711991,0.0010879062,0.0010554205,0.00065226824],"study_design_scores_gemma":[0.0019971512,0.0004200424,0.1467045,0.00006875358,0.0000075358944,0.000037815294,0.00082528323,0.006079855,0.8425342,0.0010940339,0.000017345941,0.00021350724],"about_ca_topic_score_codex":0.000046386882,"about_ca_topic_score_gemma":0.00022163721,"teacher_disagreement_score":0.12866493,"about_ca_system_score_codex":0.000018860568,"about_ca_system_score_gemma":0.000024730314,"threshold_uncertainty_score":0.42319435},"labels":[],"label_agreement":null},{"id":"W2103071544","doi":"10.1517/14728222.2012.718331","title":"Targeting IL-1 in depression","year":2012,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":162,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Neuroinflammation; Depression (economics); Antidepressant; Anakinra; Inflammation; Medicine; Interleukin; Neurogenesis; Receptor antagonist; Interleukin 6; Cytokine; Internal medicine; Immunology; Pharmacology; Receptor; Antagonist; Psychology; Neuroscience; Hippocampus; Disease","score_opus":0.11416306333005723,"score_gpt":0.37276939465907355,"score_spread":0.25860633132901634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103071544","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[5.967589e-7,0.9942522,0.000066920344,0.000055585322,0.0028310334,0.0008863178,0.000022815844,0.00017609981,0.001708439],"genre_scores_gemma":[0.00034481124,0.996892,0.000082911,0.0014387048,0.0006298845,0.0002717661,0.00006124342,0.00014138264,0.00013734387],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963116,0.0007137262,0.0007082462,0.00094805675,0.00048051836,0.00083783764],"domain_scores_gemma":[0.9982703,0.00061790645,0.000354179,0.00057520805,0.0000121614685,0.0001702432],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029076167,0.0006964881,0.0011295194,0.00039870452,0.00017141529,0.00006206387,0.0007180821,0.00047115004,0.00057292136],"category_scores_gemma":[0.00015127797,0.0005256398,0.00048490256,0.0004814055,0.000093418705,0.00019157944,0.00013843707,0.000719331,0.00075980613],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017714912,0.00025480214,0.0000015588469,0.00048217934,0.000012748041,0.00000622107,0.00042243543,0.0000016160841,0.0002733775,0.0004518106,0.0011012527,0.9969743],"study_design_scores_gemma":[0.0003380626,0.00004825583,0.0000036389135,0.0022283075,0.0000051185393,0.00001586372,0.000037308713,0.000014881899,0.00043696165,0.00010728725,0.996164,0.000600273],"about_ca_topic_score_codex":0.000007344907,"about_ca_topic_score_gemma":5.5603095e-7,"teacher_disagreement_score":0.996374,"about_ca_system_score_codex":0.0001502005,"about_ca_system_score_gemma":0.0000958155,"threshold_uncertainty_score":0.9997195},"labels":[],"label_agreement":null},{"id":"W2103127225","doi":"10.1017/s1461145710000805","title":"Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders","year":2010,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":588,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Oxidative stress; Glutathione; Prefrontal cortex; Major depressive disorder; Schizophrenia (object-oriented programming); Glutathione peroxidase; Glutathione reductase; Internal medicine; Reactive oxygen species; Bipolar disorder; Mood disorders; Endocrinology; GSTP1; Chemistry; Medicine; Psychiatry; Biochemistry; Mood; Superoxide dismutase; Enzyme; Lithium (medication); Cognition","score_opus":0.008854969531403294,"score_gpt":0.27105905027590693,"score_spread":0.26220408074450363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103127225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98641014,0.00003789658,0.00005518161,0.009446254,0.00329368,0.00030798663,0.00012698096,0.000010232087,0.0003116661],"genre_scores_gemma":[0.99369407,0.000040146457,0.000097445496,0.005901605,0.00020391807,0.0000052887954,0.0000021088772,0.00002500801,0.000030409854],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9979022,0.00034128528,0.0006034557,0.00025204883,0.0006760441,0.00022495796],"domain_scores_gemma":[0.99768245,0.0010724062,0.0007438277,0.00020063302,0.00022053943,0.00008013047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026618005,0.00018540697,0.00021870027,0.00025549458,0.00008252328,0.000037018894,0.0016009796,0.000056978057,0.00040905923],"category_scores_gemma":[0.00040065104,0.000104712744,0.00013370161,0.0003099686,0.00036812038,0.00021699675,0.000087221655,0.0007566089,0.000011040361],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029157053,0.0008240971,0.014530794,0.0000023543773,0.00008072084,0.00004815828,0.0003207267,0.000045922618,0.9759787,0.0002100015,0.00061791023,0.0044249073],"study_design_scores_gemma":[0.0067255152,0.0004133589,0.9833346,0.00001116734,0.000033250777,0.000089932626,0.000076394026,0.00011610537,0.0074492428,0.0009812909,0.00064768275,0.00012147154],"about_ca_topic_score_codex":0.00006557328,"about_ca_topic_score_gemma":0.00031595875,"teacher_disagreement_score":0.9688038,"about_ca_system_score_codex":0.000021680904,"about_ca_system_score_gemma":0.00015781511,"threshold_uncertainty_score":0.44789118},"labels":[],"label_agreement":null},{"id":"W2103254333","doi":"10.1186/1741-7015-12-73","title":"The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder","year":2014,"lang":"en","type":"article","venue":"BMC Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Medical Research Council; European Commission; King's College London; National Institute for Health and Care Research; Canada Research Chairs; GlaxoSmithKline","keywords":"Endogeny; Gene; Gene expression; Phenotype; Biology; Medicine; Genetics; Endocrinology","score_opus":0.06166797137902052,"score_gpt":0.32196649038324465,"score_spread":0.2602985190042241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103254333","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9837906,0.0047838506,0.00938921,0.0005076011,0.00006246023,0.00060589594,0.0000073269953,0.00007501824,0.00077803136],"genre_scores_gemma":[0.9990449,0.00029606023,0.00017054217,0.00030136752,0.000032074007,0.00006874498,0.000004515125,0.000026460042,0.00005536641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982268,0.00033941012,0.0002559073,0.0006179296,0.0002526659,0.0003072833],"domain_scores_gemma":[0.9972013,0.0021153055,0.00019138596,0.00031592077,0.0000648023,0.00011125032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030875142,0.00026737695,0.00034118997,0.00006437719,0.00087395473,0.000043738004,0.0002041459,0.000057220248,0.0000059593285],"category_scores_gemma":[0.003797543,0.0001444213,0.000035397232,0.00015490595,0.00068937434,0.000100787045,0.00021539924,0.00020245406,0.0000024447716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014308699,0.000036255246,0.0056254305,0.00006482678,0.000027284968,0.000013314098,0.0015173092,8.572662e-7,0.97603667,0.011626481,0.000050978786,0.004857511],"study_design_scores_gemma":[0.00907632,0.0021120007,0.19222891,0.0010027176,0.00027446664,0.00031312273,0.017941112,0.0015552307,0.6936509,0.07984547,0.0009824975,0.0010172534],"about_ca_topic_score_codex":0.00011281478,"about_ca_topic_score_gemma":0.00025257323,"teacher_disagreement_score":0.28238577,"about_ca_system_score_codex":0.000020517731,"about_ca_system_score_gemma":0.000012114222,"threshold_uncertainty_score":0.67218417},"labels":[],"label_agreement":null},{"id":"W2103413346","doi":"10.1016/j.euroneuro.2007.05.003","title":"Bright light exposure during acute tryptophan depletion prevents a lowering of mood in mildly seasonal women","year":2007,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas College; Douglas Mental Health University Institute; McGill University","funders":"","keywords":"Mood; Serotonin; Tryptophan; Profile of mood states; Psychology; Mood disorders; Psychiatry; Medicine; Internal medicine; Endocrinology; Chemistry; Anxiety; Biochemistry; Amino acid","score_opus":0.010780507546836926,"score_gpt":0.26782169527893923,"score_spread":0.2570411877321023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103413346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871369,0.00005606145,0.000059283626,0.00017859659,0.0011420375,0.00044464006,0.000017807666,0.00023490633,0.010729765],"genre_scores_gemma":[0.9978223,0.00012867108,0.000050207276,0.0009857718,0.00021425186,0.000015197633,0.0000017546627,0.0001159727,0.0006658842],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9965412,0.0005767633,0.000724186,0.00085681997,0.0003629035,0.0009381201],"domain_scores_gemma":[0.99892694,0.00015412532,0.00027826361,0.00034327435,0.000030999076,0.0002664161],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00051702454,0.0003451153,0.0003560951,0.0004245803,0.000104676976,0.000025308436,0.00069457333,0.0000759155,0.0003133705],"category_scores_gemma":[0.000104338294,0.00036029654,0.00012866333,0.00082849944,0.00015406034,0.00022670074,0.00020153238,0.00049543614,0.000098206416],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013078286,0.0005305573,0.002568354,0.00005107623,0.000021021275,0.0009704203,0.0011331565,0.00004592895,0.9905132,0.000026809294,0.0001345949,0.002697071],"study_design_scores_gemma":[0.0062113353,0.0003349896,0.5117864,0.000038198545,0.0000125576325,0.00017858029,0.000047979753,0.000021615468,0.47810096,0.00003538082,0.0028735083,0.00035847834],"about_ca_topic_score_codex":0.0000016847572,"about_ca_topic_score_gemma":0.0000046364853,"teacher_disagreement_score":0.51241225,"about_ca_system_score_codex":0.00008605897,"about_ca_system_score_gemma":0.000029547233,"threshold_uncertainty_score":0.9998849},"labels":[],"label_agreement":null},{"id":"W2103650651","doi":"10.1152/ajpgi.00184.2011","title":"Liver-brain inflammation axis","year":2011,"lang":"en","type":"review","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Sickness behavior; Inflammation; Serotonergic; Immune system; Medicine; Microglia; Neuroscience; Immunology; Central nervous system; Neuroinflammation; Neurotransmission; Blood–brain barrier; Psychology; Serotonin; Internal medicine; Receptor","score_opus":0.0331404738891459,"score_gpt":0.27513168313127234,"score_spread":0.24199120924212644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103650651","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03889444,0.95921606,0.00014195716,0.0001240456,0.0004561369,0.00061756326,0.00006291991,0.00009077758,0.00039610127],"genre_scores_gemma":[0.00972497,0.98750544,0.0014007052,0.000383365,0.000803625,0.000017025093,0.000014147545,0.000066975765,0.00008377985],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959939,0.0013482649,0.0010844839,0.0007421767,0.00018000325,0.00065113505],"domain_scores_gemma":[0.9949292,0.001618873,0.0026679907,0.00036316348,0.00014754641,0.00027321742],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002503855,0.00070302305,0.0025000235,0.00044486273,0.00016159218,0.00002502811,0.0008326327,0.00013079421,0.00023073558],"category_scores_gemma":[0.0007648424,0.0005158249,0.0007086478,0.00046976836,0.0022205538,0.00024655636,0.0002915535,0.0011340168,0.00012773313],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026133825,0.00017141059,0.0000020457173,0.0016279757,0.00007975116,0.00008863174,0.0002207167,0.0000025043364,0.10399492,0.0017620914,0.00063180993,0.8911568],"study_design_scores_gemma":[0.0016341681,0.018373182,0.0037328163,0.011303013,0.0007860693,0.024432486,0.00047823024,0.000079508434,0.0011829406,0.00533461,0.9305483,0.0021146594],"about_ca_topic_score_codex":0.00005136647,"about_ca_topic_score_gemma":0.00000277956,"teacher_disagreement_score":0.9299165,"about_ca_system_score_codex":0.000057901332,"about_ca_system_score_gemma":0.00027420575,"threshold_uncertainty_score":0.99972934},"labels":[],"label_agreement":null},{"id":"W2103719975","doi":"10.3389/fpsyt.2015.00138","title":"Cellular and Molecular Inflammatory Profile of the Choroid Plexus in Depression and Suicide","year":2015,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Choroid plexus; Inflammation; Immune system; Cerebrospinal fluid; Microglia; Monocyte; Tumor necrosis factor alpha; Medicine; Parenchyma; Immunology; Neuroscience; Central nervous system; Biology; Internal medicine; Pathology","score_opus":0.00950459196374979,"score_gpt":0.22589485374981397,"score_spread":0.2163902617860642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103719975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916273,0.0052032284,0.00016641147,0.00019123155,0.0015443176,0.0002761704,0.0000037366794,0.0000125540555,0.0009750476],"genre_scores_gemma":[0.9978092,0.000050310697,0.0017526634,0.00031153447,0.000016831238,0.000012290656,5.046909e-7,0.000012636426,0.00003403346],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99907947,0.00011969373,0.00018994557,0.00026527976,0.00017056942,0.00017502536],"domain_scores_gemma":[0.9996195,0.000014774585,0.00007271378,0.00022337929,0.00000711331,0.00006252695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015175952,0.00010348882,0.00013762004,0.00011709482,0.000028454566,0.000012638655,0.00018415273,0.000077775134,0.0000024651615],"category_scores_gemma":[0.00012399166,0.0000808119,0.000023266466,0.00023786676,0.00018439551,0.000091342416,0.000099751414,0.00016452071,6.112216e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007537643,0.00006747717,0.9399893,0.00005693017,0.0000020210994,0.000006500078,0.00056358194,0.000033424494,0.048777808,0.0004646022,0.007603145,0.002359789],"study_design_scores_gemma":[0.005278914,0.00010584633,0.65760756,0.00031690323,0.000010683236,0.000015299507,0.0040883007,0.0022061644,0.29344037,0.034850348,0.0016069317,0.00047269685],"about_ca_topic_score_codex":0.000023865814,"about_ca_topic_score_gemma":0.000036244637,"teacher_disagreement_score":0.2823818,"about_ca_system_score_codex":0.000016080054,"about_ca_system_score_gemma":0.000070639144,"threshold_uncertainty_score":0.3295414},"labels":[],"label_agreement":null},{"id":"W2103728693","doi":"10.1371/journal.pone.0116489","title":"Detection of a Novel, Integrative Aging Process Suggests Complex Physiological Integration","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; Université du Québec à Trois-Rivières; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Context (archaeology); Causality (physics); Successful aging; Disease; Biology; Gerontology; Medicine; Internal medicine","score_opus":0.18562697781837428,"score_gpt":0.3111455015212271,"score_spread":0.12551852370285282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103728693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99587876,0.000009985469,0.0026226507,0.00014729096,0.000026315543,0.00021396317,0.0000073439633,0.000086067776,0.0010076392],"genre_scores_gemma":[0.9990808,0.000004601805,0.00059972424,0.0001933924,0.000036129575,0.000023904531,0.000004462015,0.000007853984,0.00004913317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991588,0.0000634907,0.00015008615,0.00022845267,0.00026952577,0.00012965087],"domain_scores_gemma":[0.9995389,0.000075156175,0.0000987404,0.00010450623,0.00012752827,0.000055174052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000073800955,0.00009966629,0.00016923934,0.00006494113,0.000043698758,0.00001741681,0.0001383407,0.00004405518,0.000017158522],"category_scores_gemma":[0.0012258845,0.000074398355,0.000028449396,0.00030752667,0.00012939308,0.00016117663,0.000028535018,0.00013517895,0.000015632177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047186648,0.0010709987,0.000040354447,0.000021836137,0.000005267272,4.828907e-7,0.0011175305,0.000013225495,0.9965351,0.00030869056,0.000016179196,0.00082311],"study_design_scores_gemma":[0.0004926218,0.0002729248,0.0017155971,0.00007648439,0.000006728477,0.000001191699,0.00083496986,0.0076249233,0.9879645,0.0009168176,0.0000044490457,0.00008878364],"about_ca_topic_score_codex":0.0000136767485,"about_ca_topic_score_gemma":0.000027426737,"teacher_disagreement_score":0.00857063,"about_ca_system_score_codex":0.000029644405,"about_ca_system_score_gemma":0.000028402224,"threshold_uncertainty_score":0.30338767},"labels":[],"label_agreement":null},{"id":"W2104248348","doi":"10.1177/2167702614555413","title":"The Emerging Field of Nutritional Mental Health","year":2015,"lang":"en","type":"article","venue":"Clinical Psychological Science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"University of Canterbury","keywords":"Mental health; Psychological intervention; Psychology; Microbiome; Brain Structure and Function; Neuroscience; Psychiatry; Medicine; Cognition; Bioinformatics; Biology","score_opus":0.24481523659616097,"score_gpt":0.5228486893498085,"score_spread":0.27803345275364755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2104248348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91210836,0.0001960301,0.0005296236,0.061666083,0.0021070016,0.00028567572,0.0000075628896,0.000066766304,0.023032866],"genre_scores_gemma":[0.9881818,0.00019862218,0.00046140357,0.010960372,0.00007729811,0.0000040498703,2.8347785e-7,0.0000022916709,0.00011382274],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979435,0.00020546495,0.00046320976,0.00046618507,0.0005707094,0.0003509336],"domain_scores_gemma":[0.99809194,0.0011284695,0.00014711426,0.00027332388,0.0000446036,0.00031456325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024977732,0.00007187416,0.00013984686,0.000028021439,0.00038628132,0.00004172572,0.00091254624,0.000047838745,0.000059194048],"category_scores_gemma":[0.007048266,0.00004061939,0.000087685745,0.0006375034,0.0024377834,0.000112411566,0.00014943497,0.00022771365,0.00005962473],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00090670545,0.0040109954,0.012104221,0.000011878847,0.0000049870746,0.000013570245,0.00055313355,0.00001509833,0.03474592,0.17358036,0.27450138,0.49955174],"study_design_scores_gemma":[0.008758576,0.012555679,0.2323102,0.00012897381,0.00000421954,0.000116394935,0.0019610007,0.0018394982,0.032571618,0.2548528,0.4539032,0.0009978482],"about_ca_topic_score_codex":0.0000031252837,"about_ca_topic_score_gemma":0.0000018043996,"teacher_disagreement_score":0.4985539,"about_ca_system_score_codex":0.00001950052,"about_ca_system_score_gemma":0.000092646645,"threshold_uncertainty_score":0.8982115},"labels":[],"label_agreement":null},{"id":"W2104473789","doi":"10.3945/jn.114.203091","title":"Tryptophan Catabolism and Vitamin B-6 Status Are Affected by Gender and Lifestyle Factors in Healthy Young Adults","year":2015,"lang":"en","type":"article","venue":"Journal of Nutrition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"National Institute of Child Health and Human Development; Intramural Research Program; National Institutes of Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Health Research Board","keywords":"Catabolism; Tryptophan; Gerontology; Vitamin; Endocrinology; Medicine; Internal medicine; Physiology; Biology; Metabolism; Biochemistry; Amino acid","score_opus":0.024661475209098647,"score_gpt":0.2666510445337477,"score_spread":0.24198956932464907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2104473789","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968985,0.0022928286,0.00002642028,0.00029756592,0.00022670918,0.00016396522,0.00004330231,0.000011763916,0.000038965623],"genre_scores_gemma":[0.9977165,0.0018264197,0.000096379015,0.00025280626,0.000082690305,0.0000029135153,0.0000048886395,0.000011532499,0.000005856534],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99891937,0.00015805395,0.00026787,0.00016985608,0.00025483803,0.00023001105],"domain_scores_gemma":[0.99927247,0.000095852345,0.00023267379,0.000061602754,0.000059948237,0.00027748098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013662939,0.000114610644,0.00020394783,0.00020074434,0.000049347567,0.000051356317,0.000064619926,0.000076483295,0.0000032186983],"category_scores_gemma":[0.00041333295,0.00010026688,0.000026610758,0.00020256198,0.00006182052,0.00038647762,0.000019523468,0.00021766083,8.7590104e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0063025467,0.008078748,0.24480322,0.0012860637,0.000036440724,0.0005162748,0.024098584,0.000012269169,0.6572508,0.00044529728,0.047388136,0.00978157],"study_design_scores_gemma":[0.020430032,0.0013919288,0.9202176,0.00035063512,0.000013461086,0.00038467135,0.009100752,0.00013091769,0.04339048,0.001129268,0.0030837595,0.0003765272],"about_ca_topic_score_codex":0.000048571226,"about_ca_topic_score_gemma":0.000039468345,"teacher_disagreement_score":0.6754143,"about_ca_system_score_codex":0.000057871966,"about_ca_system_score_gemma":0.000042326366,"threshold_uncertainty_score":0.40887645},"labels":[],"label_agreement":null},{"id":"W2105974032","doi":"10.5455/bcp.20140918102748","title":"Glycine Reuptake Inhibitors in the Treatment of Negative Symptoms of Schizophrenia","year":2014,"lang":"en","type":"article","venue":"Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta; Alberta Health Services","keywords":"Schizophrenia (object-oriented programming); Reuptake; Glycine; Psychiatry; Reuptake inhibitor; Medicine; Pharmacology; Internal medicine; Chemistry; Antidepressant; Biochemistry; Serotonin; Anxiety; Receptor","score_opus":0.0433842249583909,"score_gpt":0.3783021859288188,"score_spread":0.3349179609704279,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105974032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98057157,0.00029277324,0.000024230158,0.006743555,0.0022383071,0.0010865522,0.000049702554,0.000048459046,0.008944865],"genre_scores_gemma":[0.993594,0.0012572272,0.00061788934,0.0036500455,0.0005161489,0.00008549618,0.0000046126393,0.000045124627,0.00022947021],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99153054,0.0028991124,0.003388081,0.00097487145,0.00059177855,0.0006155951],"domain_scores_gemma":[0.9851485,0.011961932,0.0017123923,0.0008242674,0.00016415438,0.0001887705],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020537367,0.00047430242,0.0016725931,0.0003268267,0.00007893482,0.000009145294,0.0011909491,0.000432886,0.00074046716],"category_scores_gemma":[0.0032902923,0.00033415493,0.00074266637,0.00078256417,0.0021269778,0.00004445355,0.000095805975,0.00064896274,0.00009400346],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.07256763,0.0441936,0.04043181,0.0006493605,0.0007748727,0.0001266608,0.0076823137,0.00075944647,0.20978859,0.020163082,0.07182931,0.53103334],"study_design_scores_gemma":[0.1078586,0.03265427,0.06894922,0.00026936567,0.0003705224,0.00005121864,0.0010788431,0.0010000394,0.18171722,0.007904143,0.5967882,0.0013583252],"about_ca_topic_score_codex":0.00009033559,"about_ca_topic_score_gemma":0.000021063224,"teacher_disagreement_score":0.529675,"about_ca_system_score_codex":0.000028266091,"about_ca_system_score_gemma":0.000116661424,"threshold_uncertainty_score":0.99991107},"labels":[],"label_agreement":null},{"id":"W2108490151","doi":"10.1016/s2215-0366(14)00081-9","title":"Changes in the adolescent brain and the pathophysiology of psychotic disorders","year":2014,"lang":"en","type":"review","venue":"The Lancet Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":256,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Mental Health; Economic and Social Research Council","keywords":"Psychopathology; Psychology; Neuroscience; Affect (linguistics); Brain development; Brain function; Neurotransmitter systems; Cognition; Developmental psychopathology; Autism; Developmental psychology; Psychiatry; Dopamine","score_opus":0.03944519463608208,"score_gpt":0.3202979629669697,"score_spread":0.2808527683308876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108490151","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00028597983,0.9534771,0.00001039413,0.042595048,0.0010134707,0.0013772416,0.000028415314,0.000026499662,0.0011858423],"genre_scores_gemma":[0.0019349204,0.9807812,0.000014113162,0.01638987,0.0006482265,0.00014918919,0.0000038823587,0.00003289601,0.000045698696],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961352,0.0023647798,0.0004036756,0.00045778995,0.0002282752,0.00041032713],"domain_scores_gemma":[0.9967978,0.001667192,0.00041906032,0.0010848057,0.000005766612,0.00002539493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010975847,0.0003520828,0.0012706441,0.000083891944,0.00014759779,0.000037033,0.0016504423,0.0001576893,0.000014467064],"category_scores_gemma":[0.00026273026,0.0001376274,0.00026820818,0.00048811955,0.00095873524,0.00002085724,0.00011746603,0.0007534264,0.000021220965],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020813278,0.00028733155,0.00006362999,0.011970168,0.000036945043,9.594582e-7,0.0013277611,0.0000019217969,0.0000136672315,0.065258086,0.030344244,0.89048713],"study_design_scores_gemma":[0.0016744845,0.00009509357,0.0006742428,0.002692996,0.00009428077,0.000018048746,0.00021582023,0.0000130041635,6.820552e-7,0.04119061,0.95305294,0.00027779926],"about_ca_topic_score_codex":0.0000124112175,"about_ca_topic_score_gemma":0.0004263696,"teacher_disagreement_score":0.9227087,"about_ca_system_score_codex":0.0000074598056,"about_ca_system_score_gemma":0.000058915615,"threshold_uncertainty_score":0.5612282},"labels":[],"label_agreement":null},{"id":"W2109443258","doi":"10.1371/journal.pone.0078146","title":"Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal; McGill University Health Centre","funders":"GIS-Institut des Maladies Rares; McGill University; Canadian Institutes of Health Research; Canadian Foundation for AIDS Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Kynurenine; Catabolism; Indoleamine 2,3-dioxygenase; Immune system; Inflammation; Immunology; Immune dysregulation; Medicine; Tryptophan; Biology; Metabolism; Endocrinology; Biochemistry","score_opus":0.024195648012337128,"score_gpt":0.21811033832967788,"score_spread":0.19391469031734077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109443258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99414563,0.0010145151,0.0000030668064,0.0019478659,0.000025390791,0.0006475334,0.000022755303,0.000072824,0.0021204024],"genre_scores_gemma":[0.99780476,0.0005361115,0.00023394216,0.00060260657,0.000043079483,0.00012142818,0.000003195613,0.000019246165,0.00063565286],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987175,0.000079399004,0.00018961316,0.0004337213,0.00022684666,0.00035291712],"domain_scores_gemma":[0.99940825,0.0001777524,0.00006732907,0.00019276507,0.000019816025,0.00013407464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006711424,0.00016685939,0.0002778239,0.000085569816,0.00008523481,0.00010548409,0.00014514042,0.00005989134,0.000059008315],"category_scores_gemma":[0.00037964,0.00014599772,0.000019481116,0.00019403451,0.0002556715,0.00025145995,0.00007396034,0.00015251208,0.00005571165],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027387013,0.0029270982,0.20872854,0.00043953094,0.000057909452,0.00006372298,0.0033219396,0.0000017026226,0.7473764,0.00500246,0.0010101341,0.030796703],"study_design_scores_gemma":[0.008008697,0.00014531851,0.90077835,0.00047947266,0.000031698644,0.000009662662,0.0003303895,0.005526663,0.07852861,0.004533092,0.00086675,0.00076128746],"about_ca_topic_score_codex":0.000049096798,"about_ca_topic_score_gemma":0.00003354483,"teacher_disagreement_score":0.6920498,"about_ca_system_score_codex":0.000012427769,"about_ca_system_score_gemma":0.000015083962,"threshold_uncertainty_score":0.5953615},"labels":[],"label_agreement":null},{"id":"W2110395460","doi":"10.1093/infdis/jiv037","title":"Immunosuppressive Tryptophan Catabolism and Gut Mucosal Dysfunction Following Early HIV Infection","year":2015,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"GIS-Institut des Maladies Rares; Canadian Institutes of Health Research; McGill University Health Centre; McGill University; Canadian Foundation for AIDS Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Kynurenine; Immunology; Catabolism; Immune system; CD8; Inflammation; Tumor necrosis factor alpha; T cell; Internal medicine; Lipopolysaccharide; Medicine; Biology; Endocrinology; Tryptophan; Metabolism; Amino acid; Biochemistry","score_opus":0.015506955055851654,"score_gpt":0.24776648910376667,"score_spread":0.23225953404791502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110395460","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957633,0.0011667438,0.00059319724,0.00020693388,0.0013507461,0.00014814366,0.000009168856,0.00006695963,0.0006948129],"genre_scores_gemma":[0.9989569,0.0003060223,0.0000065050167,0.00029100463,0.0003351981,0.0000042817333,0.0000010707193,0.000020858928,0.000078120465],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986007,0.00034831607,0.00030452307,0.00014122993,0.0003836814,0.00022153732],"domain_scores_gemma":[0.99887836,0.0002856278,0.00033502874,0.0001757086,0.00010905162,0.00021623932],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002472463,0.00016990108,0.00021414245,0.000175835,0.0002817559,0.00012537414,0.00016326351,0.00005405346,0.000017136876],"category_scores_gemma":[0.0012313083,0.000115199124,0.00015222897,0.00027790875,0.00014451322,0.0007070332,0.000067333305,0.00025032306,0.000023646793],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039907144,0.0025638558,0.4878868,0.00016523026,0.0005623642,0.00042062002,0.01621328,0.004113616,0.41246977,0.0026124027,0.028283184,0.04071817],"study_design_scores_gemma":[0.013040512,0.0020341214,0.9166561,0.00021390042,0.00068107364,0.0019414827,0.0013375005,0.0003771953,0.04069534,0.018010398,0.0042054136,0.00080699776],"about_ca_topic_score_codex":0.00010641452,"about_ca_topic_score_gemma":0.000010554964,"teacher_disagreement_score":0.4287693,"about_ca_system_score_codex":0.00006395127,"about_ca_system_score_gemma":0.000120358636,"threshold_uncertainty_score":0.4697684},"labels":[],"label_agreement":null},{"id":"W2110790107","doi":"10.1503/jpn.090083","title":"Oxidative damage to RNA but not DNA in the hippocampus of patients with major mental illness","year":2010,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":152,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Dentate gyrus; Schizophrenia (object-oriented programming); Hippocampus; DNA damage; Medicine; Oxidative stress; Oxidative damage; Bipolar disorder; Internal medicine; Pathology; Psychiatry; Biology; DNA; Biochemistry","score_opus":0.010657385335156363,"score_gpt":0.24943780785780975,"score_spread":0.23878042252265338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110790107","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958498,0.0000063235957,0.000035316578,0.0022219247,0.001489514,0.00019863305,0.000020691481,0.0000035988808,0.00017418645],"genre_scores_gemma":[0.9961527,0.0000110237515,0.00028564793,0.0034826011,0.00004335686,0.0000018902365,1.1497644e-7,0.0000067848805,0.000015874843],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99858356,0.00012059869,0.00030158102,0.00024333256,0.0005372993,0.0002136559],"domain_scores_gemma":[0.9992433,0.00012300226,0.00029829112,0.00018199014,0.000042443076,0.00011095238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033437007,0.00012615114,0.00015893423,0.00016731165,0.00017408052,0.00006104101,0.000636372,0.000031697193,0.000010586568],"category_scores_gemma":[0.00030613985,0.000074114694,0.000042909865,0.0005903347,0.0003857794,0.0004006542,0.000058558755,0.00036792035,0.0000011690545],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038272218,0.0005334508,0.027525233,0.000014248588,9.2813576e-7,0.000011603433,0.0011031572,0.000007937178,0.96753794,0.00092579133,0.00016847257,0.0017884889],"study_design_scores_gemma":[0.001746881,0.0013413578,0.7752708,0.00004666995,0.0000074667732,0.00007030583,0.0008086005,0.000025933276,0.21885626,0.0012124802,0.00042546928,0.0001877604],"about_ca_topic_score_codex":0.0000038694448,"about_ca_topic_score_gemma":0.000045685152,"teacher_disagreement_score":0.7486817,"about_ca_system_score_codex":0.000004761177,"about_ca_system_score_gemma":0.00008314143,"threshold_uncertainty_score":0.30223095},"labels":[],"label_agreement":null},{"id":"W2111804623","doi":"10.3899/jrheum.141505","title":"Downregulation of Tryptophan-related Metabolomic Profile in Rheumatoid Arthritis Synovial Fluid","year":2015,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Korea Institute of Science and Technology; Korea Research Council of Fundamental Science and Technology; Ministry of Science, ICT and Future Planning; National Research Foundation","keywords":"Metabolomics; Medicine; Synovial fluid; Rheumatoid arthritis; Kynurenine; Internal medicine; Metabolic pathway; Tryptophan; Kynurenine pathway; Endocrinology; Immunology; Biochemistry; Osteoarthritis; Chemistry; Metabolism; Amino acid; Pathology; Chromatography","score_opus":0.021232356611042672,"score_gpt":0.2507705211311771,"score_spread":0.22953816452013442,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111804623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962091,0.0017851272,0.00014904529,0.0006474016,0.0005100293,0.0001739052,0.000004567467,0.00001645178,0.0005043892],"genre_scores_gemma":[0.9977842,0.0019599467,0.00014368747,0.00005666029,0.000004800587,0.0000024028993,8.6257984e-7,0.000015496043,0.000031948344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99758023,0.0006951243,0.0009930783,0.00013556314,0.00032789266,0.00026811982],"domain_scores_gemma":[0.99834913,0.00046832432,0.00076702534,0.00021600223,0.000110104374,0.000089432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010081789,0.00014659854,0.0005427444,0.00029717933,0.000049172482,0.000011176666,0.00046132336,0.00012781368,0.0001262355],"category_scores_gemma":[0.0013153314,0.00010210717,0.000101940124,0.0004645117,0.0003538677,0.00024082545,0.00006189234,0.00029920254,0.000043801294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031140058,0.00072532374,0.013663268,0.000063354644,0.00009417642,0.000052827094,0.009540102,0.0027409748,0.9157996,0.031219173,0.0056536584,0.017333524],"study_design_scores_gemma":[0.03160934,0.0022485054,0.042062394,0.0010259071,0.000050472994,0.032717273,0.00543951,0.0065784315,0.8137198,0.06067442,0.002839024,0.0010349255],"about_ca_topic_score_codex":0.0000883674,"about_ca_topic_score_gemma":0.000044098757,"teacher_disagreement_score":0.102079816,"about_ca_system_score_codex":0.000035328525,"about_ca_system_score_gemma":0.00021719946,"threshold_uncertainty_score":0.41638097},"labels":[],"label_agreement":null},{"id":"W2112325336","doi":"10.1200/jco.2005.12.513","title":"Randomized Study on the Efficacy of Cognitive-Behavioral Therapy for Insomnia Secondary to Breast Cancer, Part II: Immunologic Effects","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":156,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Immune system; Breast cancer; Internal medicine; Insomnia; Randomized controlled trial; CD8; Cognitive behavioral therapy; Cancer; Oncology; Immunology; Psychiatry","score_opus":0.15819506505990197,"score_gpt":0.47448948161590876,"score_spread":0.31629441655600676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112325336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867146,0.00022752637,0.000021808657,0.00925831,0.0013069992,0.0021747139,0.000023109249,0.000011865312,0.00026108007],"genre_scores_gemma":[0.9899835,0.0004046035,0.000051226198,0.00876261,0.0005830084,0.000108972185,2.6188678e-7,0.000016156131,0.000089659734],"study_design_codex":"design_other","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99485654,0.0025428433,0.0017512628,0.00027167017,0.00030397222,0.00027372933],"domain_scores_gemma":[0.9629153,0.03513957,0.0014245065,0.00017678308,0.00020572032,0.00013809551],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0038015672,0.00018482663,0.0015812389,0.00010959817,0.00014535311,0.000014664881,0.0005131547,0.0001862751,0.00020189113],"category_scores_gemma":[0.010675917,0.00009745252,0.0007061819,0.0001896315,0.0004905473,0.00009351838,0.00007845717,0.0007716989,0.000011826345],"study_design_candidate":"randomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.43248552,0.02160626,0.0009701249,0.000005695148,0.0002046637,0.00003329221,0.0011193412,0.00003125663,0.0039028125,0.00016967008,0.0022195235,0.53725183],"study_design_scores_gemma":[0.71825486,0.061652105,0.1929901,0.00015504875,0.00021981483,0.000049524147,0.0006515031,0.00001994425,0.0113967415,0.00032522428,0.014022014,0.00026310986],"about_ca_topic_score_codex":0.000008870835,"about_ca_topic_score_gemma":0.000018585164,"teacher_disagreement_score":0.53698874,"about_ca_system_score_codex":0.000047907542,"about_ca_system_score_gemma":0.0005661161,"threshold_uncertainty_score":0.9976576},"labels":[],"label_agreement":null},{"id":"W2113325722","doi":"10.1158/1078-0432.ccr-11-1331","title":"Indoleamine 2,3-Dioxygenase Expression in Human Cancers: Clinical and Immunologic Perspectives","year":2011,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":388,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame; Montreal General Hospital","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Immune system; Medicine; Immunology; Immunotherapy; Cancer; Cancer immunotherapy; Clinical trial; Cancer research; Tryptophan Metabolism; Biology; Internal medicine; Tryptophan","score_opus":0.5876062187741322,"score_gpt":0.5994187160481229,"score_spread":0.011812497273990696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113325722","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009850085,0.98584086,9.65852e-7,0.00006855378,0.00041689954,0.001525876,0.00006273164,0.00007249917,0.0021615091],"genre_scores_gemma":[0.0059155202,0.9914554,0.000031200132,0.00010149071,0.00067150424,0.0006061267,0.000006251828,0.0000891196,0.0011234164],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.987462,0.006498568,0.0020389103,0.0022939227,0.00063070515,0.0010759125],"domain_scores_gemma":[0.99292994,0.0050451793,0.00043192855,0.0010500543,0.00016704263,0.00037586296],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0051841927,0.0005270166,0.0023834757,0.0006197078,0.0003255217,0.00011629671,0.0014988558,0.0011336585,0.00079257577],"category_scores_gemma":[0.0083137285,0.0003919663,0.00056173746,0.001317762,0.0040320866,0.00018188852,0.0012178662,0.0055276365,0.00013047358],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020691757,0.00069550594,0.00018630258,0.0025090808,0.000033184395,0.000133878,0.00025282436,1.0108037e-7,0.00010706525,0.0006043049,0.0020643454,0.9932065],"study_design_scores_gemma":[0.001800102,0.00085305143,0.0011849564,0.008562585,0.000019416186,0.0000098444525,0.00046487837,0.0000022904917,0.00021322093,0.00057357585,0.9856845,0.000631571],"about_ca_topic_score_codex":0.00043250542,"about_ca_topic_score_gemma":0.00022783485,"teacher_disagreement_score":0.99257493,"about_ca_system_score_codex":0.00033774038,"about_ca_system_score_gemma":0.0015275902,"threshold_uncertainty_score":0.9998532},"labels":[],"label_agreement":null},{"id":"W2114772839","doi":"10.1111/hdi.12200","title":"Association between depression and inflammatory/anti‐inflammatory cytokines in chronic kidney disease and end‐stage renal disease patients: A review of literature","year":2014,"lang":"en","type":"review","venue":"Hemodialysis International","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Proinflammatory cytokine; Depression (economics); Kidney disease; Dialysis; Internal medicine; Inflammation; End stage renal disease; Disease; Immunology","score_opus":0.012911946982881973,"score_gpt":0.28065331989709336,"score_spread":0.2677413729142114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114772839","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004945599,0.99177593,0.00001595153,0.0001612751,0.00024304396,0.0009138683,0.0017598037,0.0000388699,0.00014566684],"genre_scores_gemma":[0.004526119,0.9929895,0.00001358157,0.00032348337,0.0004353376,0.00013528182,0.0012825244,0.000041010087,0.0002531747],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964947,0.0005775576,0.0010344051,0.0007908772,0.0008407472,0.00026171785],"domain_scores_gemma":[0.99740213,0.00055011734,0.0011748361,0.0003631596,0.00014438543,0.000365388],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046123157,0.0004404092,0.0011708218,0.00052682747,0.00007137292,0.00011412811,0.00042060364,0.00021065632,0.0001434674],"category_scores_gemma":[0.004483317,0.00037131776,0.00038861064,0.0003734202,0.000107849875,0.0003447957,0.0002725504,0.0003810146,0.000009864956],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000114272865,0.0002834865,0.17527239,0.254713,0.00060318504,0.00009085651,0.00014223902,0.000009878567,0.0000981529,0.0007013817,0.0040999344,0.5638712],"study_design_scores_gemma":[0.0010695372,0.000016399317,0.028861122,0.11541267,0.0007514048,0.0000010626721,6.5065797e-7,0.000115037255,0.0000274743,0.00010779272,0.8531125,0.00052432047],"about_ca_topic_score_codex":0.0000023648342,"about_ca_topic_score_gemma":0.000003362418,"teacher_disagreement_score":0.8490126,"about_ca_system_score_codex":0.00036877586,"about_ca_system_score_gemma":0.0004084175,"threshold_uncertainty_score":0.9998739},"labels":[],"label_agreement":null},{"id":"W2115090099","doi":"10.2174/187152409787601897","title":"Anti-Inflammatory Effects of Antidepressants: Possibilities for Preventives Against Alzheimers Disease","year":2009,"lang":"en","type":"review","venue":"Central Nervous System Agents in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Fondation pour la Recherche sur Alzheimer","keywords":"Microglia; Inflammation; Pathogenesis; Disease; Medicine; Alzheimer's disease; Depression (economics); Mediator; Immune system; Immunology; Neuroinflammation; Pharmacology; Bioinformatics; Internal medicine; Biology","score_opus":0.034893578559110794,"score_gpt":0.31119827123184074,"score_spread":0.27630469267272995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115090099","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020913692,0.97429377,0.00002585059,0.000007073008,0.0008275713,0.0029371786,0.00023025891,0.00012377811,0.0006408266],"genre_scores_gemma":[0.09696815,0.9017432,0.000020129093,0.000060687944,0.0003693371,0.00024233718,0.00012190567,0.0001022349,0.00037205045],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9952873,0.00037848201,0.0014545443,0.0011525638,0.0007185124,0.0010086006],"domain_scores_gemma":[0.9970475,0.0007374596,0.00096197316,0.0007545418,0.000045659188,0.0004528829],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030335886,0.0008072189,0.0023442362,0.0001542832,0.000118271266,0.00004015562,0.0010367148,0.0003849169,0.000016886117],"category_scores_gemma":[0.0011429292,0.0006788855,0.00084498205,0.00035251418,0.0004057057,0.00012867711,0.000111837835,0.00043722408,0.00000504805],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012960836,0.0006355873,0.00013107098,0.65158707,0.0002291721,0.0012276382,0.00044625733,0.000028742203,0.0024947121,0.00007935791,0.0009984755,0.3420123],"study_design_scores_gemma":[0.009679722,0.0003776544,0.004103947,0.71498144,0.0045005837,0.00024749595,0.0026764974,0.00042823737,0.06444899,0.00018841912,0.19314393,0.0052230973],"about_ca_topic_score_codex":0.0000049447804,"about_ca_topic_score_gemma":4.0219518e-7,"teacher_disagreement_score":0.3367892,"about_ca_system_score_codex":0.00028112234,"about_ca_system_score_gemma":0.0005310939,"threshold_uncertainty_score":0.99956626},"labels":[],"label_agreement":null},{"id":"W2115901840","doi":"10.1371/annotation/bd02ad26-a081-4c61-88c2-ebda285b8bca","title":"Correction: Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis","year":2008,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Center for AIDS Research, University of Washington; York University; National Institutes of Health; Parkinson's Disease Foundation","keywords":"Phagocytosis; Presentation (obstetrics); Antigen processing; Antigen presentation; Methamphetamine; Antigen; Immunology; Medicine; Computer science; Pharmacology; Immune system; T cell; Surgery","score_opus":0.049424300862144575,"score_gpt":0.26436573081967635,"score_spread":0.21494142995753177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115901840","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99323344,0.0005209505,0.00026826528,0.00016214923,0.00019262683,0.00022850762,0.000020458026,0.00017782138,0.0051957746],"genre_scores_gemma":[0.99698925,0.0004548254,0.0003408363,0.00046505546,0.00009278725,0.000028020664,0.0000049446066,0.000022887421,0.0016013803],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883705,0.000081354636,0.00017147335,0.0004085421,0.0002703701,0.00023122862],"domain_scores_gemma":[0.9995203,0.00010244345,0.000079200945,0.00014573151,0.00005213361,0.00010020817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000046914935,0.00014285953,0.00014566634,0.00009325049,0.00035171543,0.000036124296,0.00010154227,0.000054312113,0.00010353725],"category_scores_gemma":[0.00044020955,0.00013283592,0.000039001923,0.00039876223,0.00018584098,0.00021777271,0.000048585105,0.00009617029,0.000069649475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020485757,0.00022439,0.016135702,0.000025011164,0.000007125943,0.00004574463,0.001530867,0.0000064820942,0.9646324,0.000028913817,0.001967169,0.015375739],"study_design_scores_gemma":[0.0004271098,0.000059382273,0.017538587,0.000019827974,0.000010892423,0.0001555547,0.0001247039,0.0014702487,0.97619295,0.000085225234,0.0037232046,0.00019231452],"about_ca_topic_score_codex":0.0000052031633,"about_ca_topic_score_gemma":0.0000044105864,"teacher_disagreement_score":0.015183425,"about_ca_system_score_codex":0.000013046173,"about_ca_system_score_gemma":0.00004815557,"threshold_uncertainty_score":0.5416892},"labels":[],"label_agreement":null},{"id":"W2117086645","doi":"10.1124/dmd.30.1.42","title":"The Role of Cytokines in the Depression of CYP1A Activity Using Cultured Astrocytes as an in Vitro Model of Inflammation in the Central Nervous System","year":2002,"lang":"en","type":"article","venue":"Drug Metabolism and Disposition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Central nervous system; In vitro; Inflammation; Depression (economics); Neuroscience; Tumor necrosis factor alpha; Cytokine; Biology; Immunology; Pharmacology; Cell biology; Biochemistry","score_opus":0.013731179577376223,"score_gpt":0.2313714355606445,"score_spread":0.21764025598326828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117086645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99893415,0.0004549774,0.00009018677,0.00005676017,0.000023683053,0.00028522828,0.000018541641,0.0000047266626,0.00013174626],"genre_scores_gemma":[0.9998262,0.00007609585,0.000040864867,0.000017440441,0.000018413804,0.000012593475,0.0000033465687,0.000004030375,0.0000010074153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879247,0.00047119273,0.00023115639,0.00013769815,0.00022963666,0.00013782675],"domain_scores_gemma":[0.99952376,0.00012015642,0.0001671159,0.00015807647,0.000016683236,0.000014231156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002800877,0.00008707328,0.00014973256,0.00007331802,0.00007633567,0.000027283984,0.00017972408,0.00003884534,4.5915337e-7],"category_scores_gemma":[0.00005450382,0.000045995886,0.00003505811,0.00026629303,0.00008136506,0.00033341735,0.00002101305,0.00008737217,8.839772e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020015953,0.0001168545,0.00041345364,0.000029780691,8.222968e-7,5.8469607e-7,0.008048192,0.0038342052,0.97789794,0.0024401483,4.7187325e-7,0.007017372],"study_design_scores_gemma":[0.000470056,0.000008383534,0.049137883,0.000041125055,0.000008785438,0.0000033529889,0.0038919097,0.18535292,0.76060736,0.00042979972,0.000003190932,0.000045231678],"about_ca_topic_score_codex":0.00035615574,"about_ca_topic_score_gemma":0.00011758556,"teacher_disagreement_score":0.2172906,"about_ca_system_score_codex":0.000009459533,"about_ca_system_score_gemma":0.000008567529,"threshold_uncertainty_score":0.18756579},"labels":[],"label_agreement":null},{"id":"W2117633457","doi":"10.2174/1381612053381701","title":"Cytokines as a Precipitant of Depressive Illness: Animal and Human Studies","year":2005,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":213,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Proinflammatory cytokine; Antidepressant; Cytokine; Medicine; Anhedonia; Neurotransmitter; Internal medicine; Endocrinology; Sickness behavior; Animal models of depression; Immunology; Dopamine; Inflammation; Central nervous system; Hippocampus","score_opus":0.3399554514491655,"score_gpt":0.4952558110698303,"score_spread":0.1553003596206648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117633457","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015513595,0.9974379,0.00010131877,0.00003239301,0.00042884573,0.0014668145,0.00006326288,0.00009029144,0.00022405613],"genre_scores_gemma":[0.0038915356,0.9953992,0.00005401349,0.000061798,0.00025977733,0.00021979272,0.000005273515,0.000059682498,0.000048943402],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965023,0.0008138889,0.0008010618,0.0009201067,0.0004427124,0.00051996316],"domain_scores_gemma":[0.99745715,0.0015271856,0.00039679627,0.00030570757,0.00006903316,0.00024414976],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002649779,0.00063621695,0.001616539,0.00022444544,0.00020833111,0.000056951383,0.00054274296,0.0001724802,0.00010643991],"category_scores_gemma":[0.0010064434,0.00047290447,0.00032913702,0.00039893336,0.00082725077,0.00016987625,0.0003467895,0.0006121428,0.00006419195],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044399407,0.00031420382,9.359513e-7,0.009489442,0.00008205833,0.000024185609,0.00017181184,6.6243786e-7,0.0011164142,0.0036962493,0.00085100334,0.98420864],"study_design_scores_gemma":[0.00068588695,0.00022986157,0.0000026117411,0.0062403064,0.0006485063,0.000068699075,0.000030419966,0.000028621187,0.006004187,0.00045429615,0.9849683,0.0006383085],"about_ca_topic_score_codex":4.858815e-7,"about_ca_topic_score_gemma":1.5526722e-7,"teacher_disagreement_score":0.98411727,"about_ca_system_score_codex":0.00006115699,"about_ca_system_score_gemma":0.00013834608,"threshold_uncertainty_score":0.99977225},"labels":[],"label_agreement":null},{"id":"W2118085818","doi":"10.1016/j.genhosppsych.2008.05.001","title":"Major depression as a risk factor for chronic disease incidence: longitudinal analyses in a general population cohort","year":2008,"lang":"en","type":"article","venue":"General Hospital Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":259,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Health Canada","keywords":"Medicine; Incidence (geometry); Population; Depression (economics); Cohort study; Cohort; Hazard ratio; Chronic bronchitis; Comorbidity; Internal medicine; Demography; Environmental health","score_opus":0.027329295761068455,"score_gpt":0.3226129173275099,"score_spread":0.29528362156644145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118085818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99523443,0.0014751602,0.00031534847,0.0002745847,0.001359542,0.00093811005,0.00020343719,0.00011078194,0.00008858369],"genre_scores_gemma":[0.99657714,0.0002281812,0.0013921319,0.00032803178,0.0007675051,0.00015501649,0.000047990805,0.000043145847,0.00046087475],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9975789,0.000109033295,0.00042138054,0.00089921546,0.00044190604,0.0005495424],"domain_scores_gemma":[0.99905115,0.000049007584,0.00021150154,0.00040198455,0.000032219956,0.00025414655],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006746175,0.0003177481,0.00029265467,0.0002156912,0.00040936616,0.000053275286,0.00033294075,0.000121054465,0.00018639286],"category_scores_gemma":[0.000257337,0.00028497633,0.00027322065,0.00046007548,0.00011324956,0.0004116093,0.0000827203,0.00022392087,0.0000444782],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021277711,0.00028711383,0.99107254,0.000033550805,0.000013528858,0.00002267291,0.00009274261,0.0011790124,0.004554596,0.0002544064,0.00067123986,0.0016058059],"study_design_scores_gemma":[0.0014480547,0.00026401298,0.9892457,0.00003336202,0.000027240423,0.000010973393,0.000013842957,0.0038940269,0.0015381909,0.0030507708,0.00006407837,0.00040971886],"about_ca_topic_score_codex":0.00070345786,"about_ca_topic_score_gemma":0.0004024389,"teacher_disagreement_score":0.003016405,"about_ca_system_score_codex":0.00013902724,"about_ca_system_score_gemma":0.00023484528,"threshold_uncertainty_score":0.99996024},"labels":[],"label_agreement":null},{"id":"W2118998411","doi":"10.1503/jpn.100175","title":"Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls","year":2011,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Kynurenic acid; Kynurenine; Kynurenine pathway; Schizophrenia (object-oriented programming); Relevance (law); Medicine; Psychology; Internal medicine; Psychiatry; Chemistry; Pharmacology; Biochemistry; Tryptophan; Amino acid; Political science","score_opus":0.01957614557203848,"score_gpt":0.23859106990872253,"score_spread":0.21901492433668404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118998411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99709576,0.00060945924,0.00037654585,0.0009283206,0.0005213662,0.00030459254,0.000017042245,0.000014238872,0.00013266041],"genre_scores_gemma":[0.99510163,0.00020157914,0.0031420027,0.0014410904,0.00004805745,0.000009657583,7.544303e-8,0.00002279391,0.000033102046],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985341,0.000094018826,0.00038853794,0.00038757612,0.00027119037,0.0003245815],"domain_scores_gemma":[0.9990128,0.0001708102,0.00040592125,0.0001581775,0.000035218523,0.00021705638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024590074,0.00018260701,0.00028245823,0.00024338417,0.00015817519,0.000047977133,0.00029827486,0.000049899398,0.000012186527],"category_scores_gemma":[0.0006465742,0.00013367253,0.000050947874,0.00035459665,0.000334554,0.00042973695,0.000032170217,0.00019737938,7.9503326e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.055259693,0.0058323694,0.43780756,0.00039399022,0.000033158107,0.0001127769,0.0013591775,0.000029120327,0.42322946,0.026496405,0.0016063115,0.04783997],"study_design_scores_gemma":[0.011090074,0.0056436122,0.94580215,0.00024584573,0.00003878365,0.00016338973,0.000075338685,0.0001254646,0.03273217,0.0030215906,0.00059616566,0.00046542654],"about_ca_topic_score_codex":0.0000027691078,"about_ca_topic_score_gemma":0.000022096841,"teacher_disagreement_score":0.5079946,"about_ca_system_score_codex":0.000008434931,"about_ca_system_score_gemma":0.0001078173,"threshold_uncertainty_score":0.54510075},"labels":[],"label_agreement":null},{"id":"W2119581482","doi":"10.1097/psy.0b013e318190d7de","title":"Chronic Interpersonal Stress Predicts Activation of Pro- and Anti-Inflammatory Signaling Pathways 6 Months Later","year":2008,"lang":"en","type":"article","venue":"Psychosomatic Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":198,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute","keywords":"Proinflammatory cytokine; Inflammation; Systemic inflammation; Lipopolysaccharide; Chronic stress; Cytokine; Interpersonal communication; Medicine; Immunology; Internal medicine; Psychology","score_opus":0.03411729842889406,"score_gpt":0.2593494799349389,"score_spread":0.22523218150604485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119581482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99667025,0.00025166367,0.00037318142,0.00063349504,0.00017709356,0.0004025062,0.0000060096863,0.00006729071,0.0014184962],"genre_scores_gemma":[0.99919945,0.00013676159,0.00008723235,0.00025530116,0.00020351325,0.000022309434,0.000004057228,0.000017742124,0.000073607196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986533,0.000070733906,0.00036673993,0.00029909285,0.00039717607,0.00021296249],"domain_scores_gemma":[0.99928343,0.00020086262,0.00018720573,0.00020408074,0.000028185656,0.00009624944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112121976,0.00016048872,0.0002594513,0.00013104876,0.000093681294,0.0000057422076,0.00015672774,0.000060403912,0.00022294317],"category_scores_gemma":[0.0002827518,0.00012060621,0.00003138161,0.00016853411,0.00040464738,0.00015821395,0.000026622127,0.0001247108,0.000007870971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033329692,0.000080355436,0.013602134,0.00047446982,0.000016291371,0.00001336614,0.0068170573,0.000017873472,0.9761524,0.00018221409,0.0006533835,0.001957102],"study_design_scores_gemma":[0.0049597663,0.00064341613,0.09894272,0.0028591643,0.000025298968,0.000106098865,0.0011347623,0.009103492,0.8807385,0.0007732382,0.00035006198,0.0003634634],"about_ca_topic_score_codex":0.0000067819883,"about_ca_topic_score_gemma":9.967084e-7,"teacher_disagreement_score":0.0954139,"about_ca_system_score_codex":0.00002302358,"about_ca_system_score_gemma":0.000044138655,"threshold_uncertainty_score":0.49181786},"labels":[],"label_agreement":null},{"id":"W2122718122","doi":"10.1002/ijc.27710","title":"Silencing IDO in dendritic cells: A novel approach to enhance cancer immunotherapy in a murine breast cancer model","year":2012,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Cure Brain Cancer Foundation; Lawson Health Research Institute","keywords":"Immunotherapy; Gene silencing; Medicine; FOXP3; Cancer research; Dendritic cell; Cancer; Cancer immunotherapy; Antigen; Breast cancer; Immunology; CD8; CTL*; Cancer vaccine; Immune system; Biology; Internal medicine; Gene","score_opus":0.025711000485738884,"score_gpt":0.33517465844344513,"score_spread":0.30946365795770625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122718122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881536,0.0028549107,0.0046187425,0.0020539996,0.0015836543,0.00017679996,0.000094189294,0.000014095974,0.00045000698],"genre_scores_gemma":[0.9933861,0.0019222583,0.00063150976,0.0032452717,0.00053507247,0.00009912819,2.6057157e-7,0.00003665592,0.00014376201],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981554,0.00004264111,0.00051856984,0.00023146348,0.00065515505,0.0003967585],"domain_scores_gemma":[0.99929464,0.000072172625,0.00024229847,0.00010311935,0.00016289105,0.00012490615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023178007,0.00017596169,0.00024807703,0.00042756967,0.00002227344,0.000051115996,0.00062890473,0.000057102563,0.00017630884],"category_scores_gemma":[0.000046541754,0.00015933323,0.00009384571,0.00035100337,0.000049359754,0.0006013762,0.0000618944,0.00033941382,0.000003963478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042790335,0.0006808801,0.004855883,0.000017895463,0.000034831442,0.000009937087,0.0026195378,0.10384041,0.87243795,0.00029599463,0.00027767042,0.0145010995],"study_design_scores_gemma":[0.006510463,0.000066539666,0.07084954,0.0017104103,0.000022009315,0.00023542067,0.0006468622,0.045679547,0.8695966,0.000518874,0.0032376111,0.00092610903],"about_ca_topic_score_codex":0.001390607,"about_ca_topic_score_gemma":0.0008340331,"teacher_disagreement_score":0.06599366,"about_ca_system_score_codex":0.0007473204,"about_ca_system_score_gemma":0.0003136762,"threshold_uncertainty_score":0.64974207},"labels":[],"label_agreement":null},{"id":"W2124107177","doi":"10.1503/jpn.100057","title":"<i>N</i>-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action","year":2011,"lang":"en","type":"review","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":485,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Acetylcysteine; Schizophrenia (object-oriented programming); Glutamatergic; Psychiatry; Psychosis; Addiction; Bipolar disorder; Medicine; Neuroscience; Psychology; Lithium (medication); Glutamate receptor; Internal medicine; Biology; Antioxidant","score_opus":0.10906288373457847,"score_gpt":0.35675784843871355,"score_spread":0.2476949647041351,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124107177","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0023168111,0.9876206,0.0010368855,0.00022216851,0.008390543,0.0003696416,0.000010097961,0.000011177697,0.000022075534],"genre_scores_gemma":[0.020654786,0.97856987,0.00033947476,0.0002343673,0.00015445478,0.0000053690587,1.4357244e-7,0.000026176953,0.000015387288],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99697787,0.00047573893,0.0011338212,0.00059977156,0.00047170086,0.000341113],"domain_scores_gemma":[0.99770564,0.00014901701,0.0016440494,0.00027942678,0.00004220704,0.0001796339],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006575538,0.0003960075,0.001060855,0.0005867264,0.00012803706,0.00007535088,0.0006763805,0.00016047004,0.000010866526],"category_scores_gemma":[0.00022256767,0.00029592068,0.00029824086,0.00090654736,0.00039309924,0.00063065963,0.00012696598,0.00080028764,0.0000014117813],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022996489,0.001173035,0.00016437608,0.016274657,0.000013984787,0.000025065357,0.00013222908,0.0000064396413,0.019867582,0.022073017,0.00017141165,0.9398682],"study_design_scores_gemma":[0.009290607,0.016290708,0.0066782054,0.1815264,0.0027264827,0.021324566,0.000700742,0.00032571456,0.0073811007,0.13509327,0.61301774,0.005644481],"about_ca_topic_score_codex":0.0000033407696,"about_ca_topic_score_gemma":0.0000086172195,"teacher_disagreement_score":0.9342238,"about_ca_system_score_codex":0.000019128815,"about_ca_system_score_gemma":0.00056582026,"threshold_uncertainty_score":0.9999493},"labels":[],"label_agreement":null},{"id":"W2124736441","doi":"10.1186/1742-4933-3-1","title":"A Need to Study the Immune Status of Frail Older Adults","year":2006,"lang":"en","type":"article","venue":"Immunity & Ageing","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Gerontology; Medicine; Disease; Immune system; Immunosenescence; Immunology; Internal medicine","score_opus":0.01846933372584375,"score_gpt":0.2649876220744169,"score_spread":0.24651828834857314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124736441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939643,0.00021191394,0.000069925554,0.00029716568,0.00012690062,0.00063352194,0.0000046896052,0.000074621974,0.0046169613],"genre_scores_gemma":[0.9992157,0.000015886293,0.000051480893,0.000311187,0.000026095511,0.000022512148,0.0000014094059,0.000018812696,0.00033690597],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99845785,0.00038284724,0.0002753657,0.00018981409,0.0002860012,0.00040812633],"domain_scores_gemma":[0.99889374,0.00034830737,0.00009382917,0.00057110935,0.00004147156,0.000051549727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002486246,0.00012999156,0.000160236,0.000095681535,0.00040773736,0.00005079893,0.0004933196,0.000033162596,0.00008768053],"category_scores_gemma":[0.00047240243,0.000102170976,0.000072150746,0.00061325735,0.00011403539,0.00010645969,0.00019562797,0.00024347576,0.000035035726],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039474142,0.0034639235,0.0060247458,0.000047262503,0.00004126401,0.00011247874,0.10023255,0.0003064375,0.81711984,0.0017658378,0.0005178842,0.06997305],"study_design_scores_gemma":[0.0021010367,0.00022380803,0.8040705,0.000070127804,0.000013636692,0.0000026562736,0.033008248,0.000042417425,0.1566332,0.00023674507,0.0033490993,0.00024857378],"about_ca_topic_score_codex":0.009822572,"about_ca_topic_score_gemma":0.00042474203,"teacher_disagreement_score":0.7980457,"about_ca_system_score_codex":0.00002519964,"about_ca_system_score_gemma":0.000036538637,"threshold_uncertainty_score":0.9967711},"labels":[],"label_agreement":null},{"id":"W2126919470","doi":"10.1038/npp.2012.79","title":"Epigenetic Mechanisms in Learned Fear: Implications for PTSD","year":2012,"lang":"en","type":"review","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":187,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Nursing Research; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada; National Institute on Aging; National Institutes of Health","keywords":"Epigenetics; Neuroscience; DNA methylation; Psychology; Fear conditioning; Context (archaeology); Chromatin; Biology; Amygdala; Gene expression; Gene; Genetics","score_opus":0.15280946910784043,"score_gpt":0.42016264296314015,"score_spread":0.2673531738552997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126919470","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000661916,0.9900708,0.00048766637,0.00069414586,0.003050747,0.0035188945,0.00016732996,0.00018078323,0.0017634162],"genre_scores_gemma":[0.00052747864,0.9934417,0.0002107277,0.0025944824,0.00028147886,0.001965493,0.000024771574,0.00016668963,0.0007871916],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99635166,0.00075224263,0.00071857235,0.0011200351,0.00012347654,0.00093402725],"domain_scores_gemma":[0.99763143,0.0012315285,0.0003614267,0.0005329516,0.000025992646,0.00021666546],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021839945,0.00053350884,0.001140978,0.0004992178,0.00015112641,0.00003626099,0.00097051397,0.00040092107,0.00039427695],"category_scores_gemma":[0.00022360089,0.00050541235,0.0004631798,0.00085196935,0.0001418786,0.00008188214,0.0001301115,0.000684934,0.00060328445],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032025306,0.0003117993,7.4535717e-7,0.001671901,0.000012844876,0.0000085099655,0.00003075216,0.0000023561693,0.014042251,0.0042276937,0.0013743899,0.9782847],"study_design_scores_gemma":[0.0010422224,0.00012810099,0.00004648176,0.00012812877,0.00017507598,0.0000710422,0.0000025598756,0.0000053210665,0.0001891939,0.0021952167,0.995589,0.0004276364],"about_ca_topic_score_codex":0.0000022586164,"about_ca_topic_score_gemma":0.000005552471,"teacher_disagreement_score":0.99421465,"about_ca_system_score_codex":0.00007686161,"about_ca_system_score_gemma":0.00016852963,"threshold_uncertainty_score":0.99973977},"labels":[],"label_agreement":null},{"id":"W2127406167","doi":"10.1139/jpn.0304","title":"Effect of loxapine on peripheral dopamine-like and serotonin receptors in patients with schizophrenia","year":2003,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University; Custom Security Industries (Canada); Queen's University","funders":"","keywords":"Schizophrenia (object-oriented programming); Dopamine; Peripheral; Serotonin; Medicine; Dopamine receptor D3; 5-HT receptor; Dopamine receptor D2; Receptor; Psychology; Pharmacology; Neuroscience; Psychiatry; Internal medicine","score_opus":0.00682525817367384,"score_gpt":0.23316081317748444,"score_spread":0.22633555500381058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127406167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985349,0.00008706751,0.0000131226125,0.00014917566,0.00090061617,0.00017387696,0.000002318285,0.0000046223863,0.00013425444],"genre_scores_gemma":[0.99928236,0.00007456898,0.00021952251,0.0003640407,0.00001728893,0.0000013707939,6.0432306e-8,0.000009039141,0.000031747575],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998614,0.00026351502,0.00029133473,0.0002758976,0.00035366972,0.00020159836],"domain_scores_gemma":[0.9993591,0.00012033033,0.0002646553,0.00011515219,0.000024354102,0.00011644279],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003283288,0.00015760139,0.000238253,0.00018412928,0.000090347945,0.000036561185,0.00016767392,0.00003692105,0.000008870257],"category_scores_gemma":[0.00036174982,0.00010411125,0.000033694654,0.0005497746,0.00030400153,0.00027132095,0.000018855193,0.0002504958,3.59751e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0056536784,0.00094827585,0.90119904,0.0001736107,0.0000035083856,0.000022056005,0.00018008538,0.0002496853,0.08283175,0.0021016714,0.00015688983,0.006479733],"study_design_scores_gemma":[0.015207162,0.026175603,0.83549726,0.00040018326,0.000018051773,0.00018064729,0.00005979925,0.000092787246,0.120655075,0.00027935315,0.000992781,0.000441284],"about_ca_topic_score_codex":0.0000010692277,"about_ca_topic_score_gemma":0.0000035216501,"teacher_disagreement_score":0.06570179,"about_ca_system_score_codex":0.00000895998,"about_ca_system_score_gemma":0.00006256433,"threshold_uncertainty_score":0.42455336},"labels":[],"label_agreement":null},{"id":"W2127751385","doi":"10.1016/j.jad.2010.01.058","title":"Oxidative damage: Consequences for major psychosis","year":2010,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Psychosis; Oxidative damage; Oxidative phosphorylation; Psychiatry; Psychology; Oxidative stress; Medicine; Biology; Internal medicine; Biochemistry","score_opus":0.015856057545734725,"score_gpt":0.29920524984437297,"score_spread":0.28334919229863825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127751385","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883829,0.000054547818,0.0031600173,0.0027620476,0.0012895213,0.0004762154,0.000028050868,0.000025954636,0.003820792],"genre_scores_gemma":[0.9977399,0.000062451836,0.0011384339,0.0007837528,0.00012053338,0.000023985787,6.838725e-7,0.000023223296,0.000107044165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875957,0.00012841045,0.00028802763,0.0002566191,0.0002797983,0.00028755976],"domain_scores_gemma":[0.99801093,0.0011415245,0.00040756437,0.00015666429,0.00015904209,0.0001242999],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033741837,0.0001836972,0.0002574118,0.00022564783,0.00019250826,0.00007093772,0.0004100243,0.00009036937,0.00013967403],"category_scores_gemma":[0.0029028095,0.0001464821,0.00024951136,0.00036381796,0.00056681136,0.00042728437,0.000024169141,0.00043888838,0.000013263032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026106575,0.00028088703,0.0015486281,0.000019562369,0.000037935384,0.000005453804,0.00058372185,0.000010372189,0.9640635,0.0052181613,0.0049927826,0.0229779],"study_design_scores_gemma":[0.005089104,0.0016371466,0.020279437,0.000046200734,0.000054988595,0.00007062825,0.002174793,0.0000833127,0.88382834,0.06741109,0.018827988,0.0004969884],"about_ca_topic_score_codex":0.000022733922,"about_ca_topic_score_gemma":0.00036392888,"teacher_disagreement_score":0.080235206,"about_ca_system_score_codex":0.000021229342,"about_ca_system_score_gemma":0.00010236557,"threshold_uncertainty_score":0.59733665},"labels":[],"label_agreement":null},{"id":"W2128847103","doi":"10.1002/ajmg.b.30898","title":"Peripheral gene expression profiling of CCK‐4‐induced panic in healthy subjects","year":2008,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Panic; Gene expression profiling; Panic disorder; Microarray; Gene expression; Gene; Medicine; False discovery rate; Candidate gene; Microarray analysis techniques; Bioinformatics; Biology; Genetics; Psychiatry; Anxiety","score_opus":0.033924170272144026,"score_gpt":0.2943838587265877,"score_spread":0.26045968845444367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128847103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948731,0.0017926774,0.000728673,0.0009019208,0.0013358532,0.0002478897,0.000005988328,0.000018638595,0.00009524112],"genre_scores_gemma":[0.9783878,0.013249606,0.0062440084,0.0016108474,0.00043244482,0.0000045104553,9.717944e-7,0.000061167164,0.000008654459],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.994257,0.0007901638,0.0015864649,0.00051167916,0.0021753244,0.000679374],"domain_scores_gemma":[0.9971822,0.0003549496,0.0011769242,0.00046502723,0.00014394322,0.00067699],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005617021,0.0003337405,0.0007361509,0.00044061267,0.00012774685,0.000018094217,0.0011093097,0.0001485864,0.000080181766],"category_scores_gemma":[0.00083680113,0.0002945144,0.00023850217,0.0015613217,0.00062420254,0.000054302196,0.00016575532,0.00088697433,0.000007666166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012914601,0.002134858,0.06540281,0.000113987786,0.000028112325,0.0008979858,0.0015821648,0.0021568376,0.87702125,0.00004975134,0.0007860337,0.048534717],"study_design_scores_gemma":[0.011879811,0.020433746,0.11938162,0.00028108896,0.0000782952,0.004606908,0.0012612011,0.004165855,0.83339745,0.00031300113,0.0027966013,0.0014044483],"about_ca_topic_score_codex":0.000010287119,"about_ca_topic_score_gemma":0.0000063699604,"teacher_disagreement_score":0.05397881,"about_ca_system_score_codex":0.00004307443,"about_ca_system_score_gemma":0.0010452464,"threshold_uncertainty_score":0.9999507},"labels":[],"label_agreement":null},{"id":"W2129376177","doi":"10.1517/13543784.2014.998334","title":"Novel investigational drugs targeting IL-6 signaling for the treatment of depression","year":2015,"lang":"en","type":"review","venue":"Expert Opinion on Investigational Drugs","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Major depressive disorder; Antidepressant; Signal transduction; Neuroscience; Drug development; Medicine; Function (biology); Bioinformatics; Pharmacology; Drug; Psychology; Biology; Psychiatry; Cognition; Anxiety; Cell biology","score_opus":0.15072664658707133,"score_gpt":0.37481996680945256,"score_spread":0.22409332022238124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129376177","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000045159537,0.9931707,0.0005360561,0.00096484256,0.0016703465,0.0022782206,0.00076020113,0.000103856524,0.00047063283],"genre_scores_gemma":[0.00011662049,0.99018604,0.004020354,0.0011713298,0.0014925099,0.0016167028,0.0009549974,0.00011969507,0.0003217631],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961449,0.00030100334,0.0010560703,0.00093243463,0.001156493,0.00040911115],"domain_scores_gemma":[0.9937524,0.004402179,0.0009066635,0.00046002676,0.0001910773,0.00028762245],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048304378,0.00065396604,0.00096889155,0.0002661726,0.00050221337,0.00008749402,0.0006626263,0.00030637512,0.00006341342],"category_scores_gemma":[0.0013044701,0.00042723652,0.0007457358,0.00051826896,0.0006365072,0.00018968398,0.00007403452,0.00024738623,0.00004261725],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011348134,0.0011708066,0.0000031506238,0.0022586475,0.00024025362,0.0000012345428,0.00794488,0.0015447895,0.004256363,0.054231767,0.05587293,0.8723617],"study_design_scores_gemma":[0.00093979173,0.00018174743,0.0000013628835,0.0026390802,0.00002457171,0.000008326073,0.00020881726,0.00076636253,0.0052821557,0.002508902,0.98699063,0.0004482626],"about_ca_topic_score_codex":0.000027375127,"about_ca_topic_score_gemma":2.6898863e-7,"teacher_disagreement_score":0.9311177,"about_ca_system_score_codex":0.00030912328,"about_ca_system_score_gemma":0.0011984864,"threshold_uncertainty_score":0.99981797},"labels":[],"label_agreement":null},{"id":"W2129605044","doi":"10.1016/j.jad.2006.08.015","title":"Changes in plasma cholesterol in mood disorder patients: Does treatment make a difference?","year":2006,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Hamilton Anxiety Rating Scale; Hamilton Rating Scale for Depression; Internal medicine; Mania; Depression (economics); Anxiety; Mood; Young Mania Rating Scale; Rating scale; Bipolar disorder; Medicine; Psychology; Psychiatry; Gastroenterology; Major depressive disorder","score_opus":0.0077042365353111614,"score_gpt":0.23277503385765239,"score_spread":0.22507079732234123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129605044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970316,0.00008504619,0.00003355884,0.0008433438,0.00030348366,0.0005335482,0.000019159961,0.000017018461,0.0011332011],"genre_scores_gemma":[0.9992847,0.00028478235,0.000021746911,0.00015573027,0.000051592757,0.000044589033,0.0000027081317,0.000029455272,0.00012473513],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99809104,0.00027783445,0.000441304,0.0003622355,0.00037215673,0.00045543484],"domain_scores_gemma":[0.9990275,0.00036835062,0.000327633,0.0001601619,0.000043842923,0.00007253201],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009878374,0.00031576268,0.00043538073,0.00063773635,0.000064413805,0.00005807249,0.00026761633,0.000104081155,0.00003037658],"category_scores_gemma":[0.00027325755,0.00021381782,0.00014422523,0.000627057,0.00014204996,0.0002053827,0.000039976567,0.00027710266,0.0000057492375],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037744793,0.0044455305,0.8599474,0.000027960832,0.000016196856,0.000024467807,0.0018510415,0.0005698818,0.008039518,0.00020220413,0.000030315565,0.12446804],"study_design_scores_gemma":[0.010139702,0.0013959869,0.97261935,0.00009174217,0.00001007052,0.0000058114224,0.0011818548,0.00015847707,0.010866149,0.0027724162,0.00046603652,0.00029241742],"about_ca_topic_score_codex":0.0006851848,"about_ca_topic_score_gemma":0.10390515,"teacher_disagreement_score":0.12417563,"about_ca_system_score_codex":0.00024589984,"about_ca_system_score_gemma":0.000054525357,"threshold_uncertainty_score":0.91244626},"labels":[],"label_agreement":null},{"id":"W2129848727","doi":"10.1038/npp.2015.337","title":"Enzymatic Depletion of the Polysialic Acid Moiety Associated with the Neural Cell Adhesion Molecule Inhibits Antidepressant Efficacy","year":2015,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Neurogenesis; Polysialic acid; Antidepressant; Neural cell adhesion molecule; Neuroplasticity; Neuroscience; Neurotrophic factors; Synaptic plasticity; Hippocampal formation; Pharmacology; Psychology; Hippocampus; Medicine; Chemistry; Internal medicine; Receptor; Cell adhesion; Biochemistry","score_opus":0.028477103050191334,"score_gpt":0.2735731358607056,"score_spread":0.24509603281051426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129848727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949786,0.00013748575,0.000026504395,0.002111234,0.0007551439,0.00066358567,0.000010681781,0.00008964863,0.0012271389],"genre_scores_gemma":[0.99393517,0.000023451812,0.0000059618546,0.0057569095,0.000055992852,0.000027309496,0.000001643421,0.000039325918,0.00015425688],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99706835,0.0012651735,0.00029902818,0.00046437784,0.0005066067,0.00039647619],"domain_scores_gemma":[0.99863523,0.0003973676,0.00032630333,0.00044968267,0.00007670087,0.00011470471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020833654,0.00023420129,0.00025234293,0.00006758685,0.00019906634,0.00002958788,0.0007108585,0.00008679803,0.00003766587],"category_scores_gemma":[0.00044607272,0.00013031955,0.00014468495,0.0008196789,0.00040401443,0.000102363585,0.00015357109,0.00042375183,0.000024936955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002848115,0.00037088516,0.00042479404,0.000009853661,0.000011106355,0.000014741835,0.00039744904,0.0006208759,0.992086,0.00002420958,0.0054058065,0.00034947973],"study_design_scores_gemma":[0.0044095977,0.00040499488,0.021908833,0.000014076088,0.000056540997,0.000027418359,0.000085081956,0.0014693891,0.97081935,0.000029260456,0.0005975992,0.00017784355],"about_ca_topic_score_codex":0.000010230657,"about_ca_topic_score_gemma":0.000005671688,"teacher_disagreement_score":0.021484038,"about_ca_system_score_codex":0.000025265546,"about_ca_system_score_gemma":0.00006124702,"threshold_uncertainty_score":0.5314277},"labels":[],"label_agreement":null},{"id":"W2130066056","doi":"10.1016/j.schres.2015.10.015","title":"A case of pseudo-Stauffer's syndrome related to asenapine use","year":2015,"lang":"en","type":"letter","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Asenapine; Medicine; Adverse effect; Psychiatry; Intensive care medicine; Internal medicine; Schizophrenia (object-oriented programming); Antipsychotic","score_opus":0.13235144636557403,"score_gpt":0.36412159391249865,"score_spread":0.23177014754692463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130066056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7516358,0.00013519767,0.000004872035,0.24296609,0.0006171024,0.0018728438,0.000849735,0.00022595053,0.001692431],"genre_scores_gemma":[0.7779879,0.00013992903,0.0016150333,0.16777195,0.0010701171,0.000389547,0.00027245676,0.0006382789,0.050114788],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.991548,0.0019321628,0.0007810102,0.0015679004,0.002553065,0.0016178498],"domain_scores_gemma":[0.9948301,0.0019788202,0.0001872249,0.0018743371,0.0006031458,0.0005263778],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015919664,0.000555591,0.00084371865,0.002047181,0.00030830354,0.00028965753,0.0014847136,0.0010842249,0.0006295004],"category_scores_gemma":[0.007086967,0.0005024454,0.00025272256,0.0032581438,0.0008172869,0.00031392553,0.0009374894,0.0055283513,0.0019521968],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051102863,0.00010434542,0.000004302298,0.00020045423,0.000031668926,0.103952035,0.00021440483,0.000007389374,0.011540755,0.00047839715,0.88197297,0.000982233],"study_design_scores_gemma":[0.008837538,0.0034840647,0.00019591139,0.001145888,0.000068167086,0.06728783,0.00027246698,0.00045907576,0.029522793,0.018766856,0.8670454,0.0029140133],"about_ca_topic_score_codex":0.0004883234,"about_ca_topic_score_gemma":0.000071420014,"teacher_disagreement_score":0.075194135,"about_ca_system_score_codex":0.00022718452,"about_ca_system_score_gemma":0.0009182366,"threshold_uncertainty_score":0.99974275},"labels":[],"label_agreement":null},{"id":"W2130547250","doi":"10.1177/070674370505000507","title":"A Study of HLA-Linked Genes in a Monosymptomatic Psychotic Disorder in an Indian Bengali Population","year":2005,"lang":"en","type":"article","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Delusional disorder; Human leukocyte antigen; Etiology; Psychiatry; Population; Medicine; Psychology; Immunology; Psychosis; Antigen","score_opus":0.02497769584152417,"score_gpt":0.2820565824514988,"score_spread":0.25707888660997463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130547250","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99584484,0.00032498766,0.0000022508545,0.0029769752,0.00043265076,0.00033736948,0.0000037312793,0.0000043576865,0.00007285245],"genre_scores_gemma":[0.9992002,0.000009452016,0.00020821254,0.00044063744,0.00010943859,0.000004510778,5.75526e-7,0.000017975195,0.000008992301],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99830747,0.00035591572,0.00064968294,0.00016196778,0.0002336529,0.0002912868],"domain_scores_gemma":[0.9991273,0.00005548788,0.00031251545,0.00026705713,0.00002558068,0.00021201359],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004160857,0.00013368815,0.00023212827,0.000725799,0.00011891369,0.000045072113,0.0005078429,0.000064603315,0.00004429896],"category_scores_gemma":[0.00009066337,0.000105020205,0.000059164777,0.00069825904,0.000065421955,0.00027847168,0.000007014909,0.00032597166,0.0000037499185],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004632761,0.00055448286,0.9781139,0.00001602376,0.0000072891235,0.00002018247,0.010539071,0.0041911798,0.00018297945,0.0008827807,0.00004835539,0.0053974288],"study_design_scores_gemma":[0.002097861,0.00038821305,0.98413956,0.000080297265,0.000009807895,0.00004578423,0.0067678373,0.00040706593,0.000030149185,0.005873045,0.000023426315,0.00013696632],"about_ca_topic_score_codex":0.02065762,"about_ca_topic_score_gemma":0.959778,"teacher_disagreement_score":0.9391204,"about_ca_system_score_codex":0.00009487303,"about_ca_system_score_gemma":0.00050287246,"threshold_uncertainty_score":0.9858639},"labels":[],"label_agreement":null},{"id":"W2131763634","doi":"10.1098/rstb.2012.0212","title":"Beyond the monoaminergic hypothesis: neuroplasticity and epigenetic changes in a transgenic mouse model of depression","year":2012,"lang":"en","type":"review","venue":"Philosophical Transactions of the Royal Society B Biological Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":170,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Institut National de la Santé et de la Recherche Médicale; European Commission","keywords":"Monoaminergic; Monoamine neurotransmitter; Neuroscience; Epigenetics; Neuroplasticity; Antidepressant; Hippocampus; Glucocorticoid receptor; Mood disorders; Psychology; Biology; Serotonin; Medicine; Endocrinology; Internal medicine; Glucocorticoid; Receptor; Psychiatry; Gene; Genetics","score_opus":0.16596730025959702,"score_gpt":0.30042624137232093,"score_spread":0.1344589411127239,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131763634","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.077630356,0.91537094,0.0015860556,0.0026750406,0.0002484455,0.0017201435,0.00036718557,0.000064683496,0.00033712818],"genre_scores_gemma":[0.5061062,0.49357644,0.000102021586,0.000114909315,0.00002631186,0.000050604074,2.622442e-7,0.000008210448,0.000015067203],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9974648,0.00060933933,0.0005173372,0.0005926553,0.0004021617,0.00041375594],"domain_scores_gemma":[0.997532,0.0017935451,0.00026700838,0.00029433143,0.000015391452,0.000097738695],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00051233196,0.00034159215,0.0008009844,0.000050758314,0.00040489755,0.000022015258,0.0011881087,0.00035815517,0.00003137473],"category_scores_gemma":[0.00018829716,0.00014783572,0.0007167059,0.00074586243,0.0032100799,0.000050518924,0.00008532751,0.00059678726,0.0000012488233],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012514366,0.003140118,0.00041999813,0.00652912,0.00017973853,8.091409e-7,0.0015278369,0.020534417,0.02032853,0.0055550477,0.000013925355,0.9416453],"study_design_scores_gemma":[0.007913621,0.0074260384,0.005771491,0.01503952,0.007891362,0.00011851879,0.0014429925,0.27789524,0.14240699,0.5047954,0.017323662,0.0119751915],"about_ca_topic_score_codex":0.00001284686,"about_ca_topic_score_gemma":0.000009055081,"teacher_disagreement_score":0.92967016,"about_ca_system_score_codex":0.00002079779,"about_ca_system_score_gemma":0.00006713738,"threshold_uncertainty_score":0.9995026},"labels":[],"label_agreement":null},{"id":"W2131908174","doi":"10.2174/138955711795906941","title":"Anti-Inflammatory Properties of Antipsychotics Via Microglia Modulations: Are Antipsychotics a &amp;#x2018;Fire Extinguisher&amp;#x2019; in the Brain of Schizophrenia?","year":2011,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Schizophrenia (object-oriented programming); Dopamine; Microglia; Neuroscience; Antipsychotic; Dopamine receptor D2; Medicine; Psychosis; Dopamine hypothesis of schizophrenia; Dementia; Psychology; Psychiatry; Inflammation; Internal medicine; Disease","score_opus":0.11974580279900147,"score_gpt":0.3342569643533351,"score_spread":0.21451116155433358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131908174","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.043165226,0.953791,0.000079955375,0.00010851083,0.00041986915,0.0019056534,0.00006288106,0.00003339773,0.00043348304],"genre_scores_gemma":[0.0033981358,0.9935736,0.0019027204,0.00025133003,0.00029031298,0.00015090019,0.000037526996,0.00010773606,0.00028775106],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99304366,0.0009949716,0.003349586,0.0011337947,0.0007663349,0.0007116707],"domain_scores_gemma":[0.99455196,0.0006182942,0.0026593397,0.0019331932,0.00010065326,0.00013657514],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0022263182,0.0010122893,0.0036197905,0.00029439898,0.000097499214,0.00003490845,0.0022611404,0.00069245877,0.00014974317],"category_scores_gemma":[0.004609972,0.0006914014,0.0007356047,0.0014728449,0.0011311341,0.00012254335,0.00016398124,0.0014919543,0.0000569537],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042561098,0.0023064003,0.0006096998,0.24023482,0.00011780687,0.000032834232,0.00475147,0.000003406799,0.1705821,0.00006166953,0.0035945973,0.57727957],"study_design_scores_gemma":[0.0007648545,0.00003317582,0.000152382,0.06914841,0.00018288693,0.00017569672,0.00020448223,0.0000029838636,0.001471969,0.00011286271,0.9270387,0.0007115813],"about_ca_topic_score_codex":0.000015257454,"about_ca_topic_score_gemma":0.00004043434,"teacher_disagreement_score":0.9234441,"about_ca_system_score_codex":0.00008358136,"about_ca_system_score_gemma":0.00033733484,"threshold_uncertainty_score":0.99955374},"labels":[],"label_agreement":null},{"id":"W2132838767","doi":"10.1016/j.jpsychires.2009.09.001","title":"Interleukin 10 family gene polymorphisms are not associated with major depressive disorder and panic disorder phenotypes","year":2009,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Vedecká Grantová Agentúra MŠVVaŠ SR a SAV","keywords":"Panic disorder; Haplotype; Single-nucleotide polymorphism; Genetics; SNP; Allele; Biology; Bipolar disorder; Locus (genetics); Genotype; Gene; Anxiety; Psychiatry; Mood; Psychology","score_opus":0.038553010683691255,"score_gpt":0.31736106820870513,"score_spread":0.27880805752501386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132838767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890491,0.003790439,0.00029497113,0.005274497,0.00018835535,0.00028918096,0.000016433436,0.000026038424,0.0010709952],"genre_scores_gemma":[0.9970914,0.0006893723,0.0002800591,0.00064528716,0.00020194107,0.0000052945443,0.0000012799377,0.000034803514,0.0010505682],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9963563,0.00056841754,0.00054242206,0.00044741883,0.0013978007,0.00068760494],"domain_scores_gemma":[0.9979796,0.0005947515,0.0005041301,0.00030046035,0.00035049467,0.00027059452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080504065,0.00024986506,0.0004044587,0.00074616354,0.00041800662,0.00021334822,0.000684625,0.0001400739,0.00014102297],"category_scores_gemma":[0.0012188851,0.00017593369,0.00013353661,0.0014970457,0.00027684885,0.00030373386,0.00009123459,0.0009625217,0.00002726616],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015611911,0.010071598,0.21878839,0.00018620488,0.0006379254,0.001731649,0.003899824,0.0004874233,0.49378932,0.003878046,0.067229435,0.18368828],"study_design_scores_gemma":[0.010480988,0.004543525,0.96455747,0.00019709503,0.000077682365,0.00022691481,0.0012299989,0.00027827374,0.00953941,0.005757071,0.0024503318,0.000661249],"about_ca_topic_score_codex":0.000037100035,"about_ca_topic_score_gemma":0.000073777235,"teacher_disagreement_score":0.7457691,"about_ca_system_score_codex":0.00007432908,"about_ca_system_score_gemma":0.00022016732,"threshold_uncertainty_score":0.71743673},"labels":[],"label_agreement":null},{"id":"W2133551071","doi":"10.2217/nmt.14.5","title":"Depression Versus Dementia: Is This Construct Still relevant?","year":2014,"lang":"en","type":"review","venue":"Neurodegenerative Disease Management","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; Ontario Brain Institute; University of Toronto; St. Michael's Hospital; University of Calgary","funders":"","keywords":"Dementia; Prodrome; Depression (economics); Cognitive decline; Cognition; Late life depression; Cognitive impairment; Psychology; Etiology; Population; Clinical psychology; Psychiatry; Medicine; Neurodegeneration; Disease; Internal medicine","score_opus":0.050342392182383476,"score_gpt":0.31858143763878555,"score_spread":0.2682390454564021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133551071","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005186708,0.9717967,0.00029450766,0.00012243958,0.0022704138,0.0023998644,0.00041085365,0.00027415037,0.022379212],"genre_scores_gemma":[0.00069115125,0.99382126,0.00016050925,0.0018469522,0.00023347726,0.00047706088,0.00011683066,0.00015157914,0.0025011543],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9944919,0.00095760956,0.0007746831,0.002156475,0.0009046233,0.0007147344],"domain_scores_gemma":[0.99725926,0.00036628896,0.00052921165,0.0013282794,0.00004672036,0.00047023452],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001389651,0.001003873,0.0012485202,0.00038809862,0.00040935667,0.00026150205,0.0010601905,0.00015926876,0.0011013543],"category_scores_gemma":[0.00028690932,0.0008318973,0.0008094409,0.0005932847,0.00027979075,0.00017486185,0.00080956175,0.00045492075,0.001214524],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013784839,0.00022562935,0.0000022846814,0.008247816,0.00025150905,0.00030513405,0.00003709152,0.000010880139,0.000015023513,0.009864914,0.040401965,0.9404999],"study_design_scores_gemma":[0.0011238185,0.000067891546,0.000008206596,0.00161029,0.0014019615,0.0000028283566,0.000007710647,0.0001316901,0.0002261003,0.00012382373,0.99451584,0.0007798604],"about_ca_topic_score_codex":0.0000018569109,"about_ca_topic_score_gemma":0.0000014488113,"teacher_disagreement_score":0.95411384,"about_ca_system_score_codex":0.00009779487,"about_ca_system_score_gemma":0.00011646114,"threshold_uncertainty_score":0.99981177},"labels":[],"label_agreement":null},{"id":"W2135167226","doi":"10.1002/ajmg.b.32330","title":"A genome‐wide association study of suicidal behavior","year":2015,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Université Laval; McGill University; Institut Universitaire en Santé Mentale de Québec","funders":"National Institute of Mental Health","keywords":"Genome-wide association study; Single-nucleotide polymorphism; Suicidal ideation; Genetic association; Medicine; Poison control; SNP; Disease; Psychiatry; Suicide prevention; Bioinformatics; Genetics; Biology; Genotype; Gene; Internal medicine; Medical emergency","score_opus":0.03330493196254541,"score_gpt":0.3017140729601594,"score_spread":0.268409140997614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135167226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958201,0.0005721336,0.0002559083,0.0011785583,0.0016379305,0.000331385,0.000008257909,0.000019569705,0.00017612508],"genre_scores_gemma":[0.9965407,0.0010368384,0.00059140427,0.0012788577,0.00043911955,0.000006550006,7.5132334e-7,0.000050491053,0.000055266504],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99317104,0.0008905881,0.0013802627,0.0003832911,0.0036706114,0.0005042391],"domain_scores_gemma":[0.99589574,0.0006453924,0.0017528982,0.00042699708,0.00038909947,0.00088985276],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011363064,0.0002775235,0.00063946197,0.0003471033,0.00007261134,0.00004604583,0.0012054464,0.00011367064,0.000062989966],"category_scores_gemma":[0.0032407392,0.0002482287,0.00019249538,0.0013107772,0.00028488893,0.00004554308,0.00018967956,0.00064181664,0.000020708372],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003406801,0.0072022793,0.94509786,0.00002384197,0.000111932604,0.00043039923,0.0028700242,0.001903613,0.007329809,0.000015389523,0.0045012585,0.03017291],"study_design_scores_gemma":[0.010839075,0.030011522,0.9233613,0.000025141118,0.00060451607,0.00040007077,0.0072550145,0.00048078687,0.00436663,0.0002181473,0.021496,0.0009417792],"about_ca_topic_score_codex":0.000017457614,"about_ca_topic_score_gemma":0.000019791589,"teacher_disagreement_score":0.029231131,"about_ca_system_score_codex":0.000075638345,"about_ca_system_score_gemma":0.0006673713,"threshold_uncertainty_score":0.999997},"labels":[],"label_agreement":null},{"id":"W2135344776","doi":"10.1517/14656566.8.11.1615","title":"Thiazolidinediones: novel treatments for cognitive deficits in mood disorders?","year":2007,"lang":"en","type":"review","venue":"Expert Opinion on Pharmacotherapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Mount Sinai Hospital; McMaster University; University of Toronto; University Health Network","funders":"GlaxoSmithKline; AstraZeneca; Eli Lilly and Company","keywords":"Mood disorders; Mood; Medicine; Cognition; Disease; Bioinformatics; Neuroscience; Psychiatry; Psychology; Clinical psychology; Anxiety; Internal medicine; Biology","score_opus":0.18067765430314467,"score_gpt":0.45982508818113105,"score_spread":0.27914743387798635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135344776","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000019918843,0.98940617,0.0010380698,0.00014597381,0.002110599,0.0042774677,0.00039307633,0.000172458,0.0024362733],"genre_scores_gemma":[0.00011620071,0.9946314,0.00012313666,0.0023067205,0.0005346866,0.0016331362,0.00015279854,0.00021119167,0.0002907115],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99660516,0.00019417626,0.00075915887,0.0012466331,0.00044087434,0.0007539891],"domain_scores_gemma":[0.99750847,0.0016412565,0.00036172027,0.00029298954,0.000029805873,0.00016574936],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019581454,0.00088470866,0.0012623287,0.00070237275,0.00018087358,0.00006549636,0.00053217233,0.00036923547,0.00018263557],"category_scores_gemma":[0.0001323644,0.0007184922,0.0006805043,0.0007755309,0.0001095766,0.00017129682,0.000034329987,0.00040587084,0.000114079085],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003389442,0.0017448753,8.5277753e-7,0.0004917542,0.00008185641,0.0000020186644,0.0004699986,0.000001102867,0.00054456864,0.0007497689,0.00086062076,0.99471366],"study_design_scores_gemma":[0.006916264,0.00039492766,0.0000020764867,0.0036126235,0.000015006304,0.00000971995,0.00008653871,0.000032743148,0.0032039585,0.00009189834,0.9848744,0.0007598115],"about_ca_topic_score_codex":0.000012791113,"about_ca_topic_score_gemma":0.0000069444086,"teacher_disagreement_score":0.9939538,"about_ca_system_score_codex":0.00018681173,"about_ca_system_score_gemma":0.00015632682,"threshold_uncertainty_score":0.9995266},"labels":[],"label_agreement":null},{"id":"W2136168452","doi":"10.2190/l811-0738-10ng-7157","title":"Self-Reported Allergies and Their Relationship to Several Axis I Disorders in a Community Sample","year":2007,"lang":"en","type":"article","venue":"The International Journal of Psychiatry in Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Allergy; Sample (material); Medicine; Dermatology; Environmental health; Psychology; Immunology; Chemistry; Chromatography","score_opus":0.03287465353961431,"score_gpt":0.3217028529184775,"score_spread":0.28882819937886317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136168452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9514231,0.0001808145,0.0016895155,0.04419177,0.0010735143,0.00012167444,0.0000027302654,0.000011459502,0.0013053974],"genre_scores_gemma":[0.995754,0.00016819946,0.0011583382,0.0027026727,0.00018900078,0.0000014879776,0.0000010904671,0.000007923075,0.000017266286],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99859554,0.00020529627,0.00057634787,0.00009596833,0.00037477427,0.00015208039],"domain_scores_gemma":[0.99772424,0.0017752675,0.00023523015,0.00014157959,0.00005661185,0.000067070156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019619372,0.00010508159,0.00015803296,0.00041253417,0.00008100002,0.000017181077,0.0005753644,0.000037924463,0.000035718676],"category_scores_gemma":[0.0021504427,0.000065307286,0.00003722003,0.0003498757,0.00013301517,0.0001281995,0.00006981402,0.0005963876,0.0000014753452],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002000953,0.001389351,0.87792885,0.000052888634,0.00017231479,0.000051165647,0.07042223,0.0015638851,0.006505067,0.023447862,0.004036658,0.012428788],"study_design_scores_gemma":[0.0033219268,0.00047124078,0.8590576,0.00031543538,0.000008798609,0.0002889499,0.017434321,0.00030819676,0.00029660104,0.115057886,0.0032850634,0.00015395231],"about_ca_topic_score_codex":0.00038468753,"about_ca_topic_score_gemma":0.008574372,"teacher_disagreement_score":0.09161002,"about_ca_system_score_codex":0.00006285063,"about_ca_system_score_gemma":0.000066112174,"threshold_uncertainty_score":0.47847012},"labels":[],"label_agreement":null},{"id":"W2136567014","doi":"10.1186/s12974-014-0151-1","title":"The common inflammatory etiology of depression and cognitive impairment: a therapeutic target","year":2014,"lang":"en","type":"review","venue":"Journal of Neuroinflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":229,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"Ontario Neurotrauma Foundation","keywords":"Kynurenine; Depression (economics); Medicine; Psychological intervention; Drug; Etiology; Kynurenine pathway; Inflammation; Cognition; Psychiatry; Bioinformatics; Immunology; Biology; Tryptophan","score_opus":0.029606446560247933,"score_gpt":0.3130024408593819,"score_spread":0.283395994299134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136567014","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.022850476,0.97549736,0.00012789087,0.000102257,0.0004379143,0.00070317765,0.000008429088,0.000015884743,0.00025660216],"genre_scores_gemma":[0.027983025,0.9717555,0.000013538404,0.00003883649,0.00014293277,0.000009949608,0.0000025012944,0.000031174066,0.00002253659],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996813,0.001306945,0.0011528584,0.00020146898,0.00033209965,0.00019361998],"domain_scores_gemma":[0.9943504,0.0025946207,0.0026998294,0.00018878361,0.000095913965,0.000070502865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006803685,0.00025618233,0.00088874524,0.00022913083,0.00016996036,0.00005570899,0.00033893937,0.00016938365,0.000008417844],"category_scores_gemma":[0.0007414882,0.0001500776,0.00030851312,0.00016890437,0.00026021607,0.00017532232,0.000081803766,0.0005267243,0.00000693734],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012854721,0.000043835593,0.000034864377,0.002678785,0.00004682449,0.000025137151,0.00015477794,0.000005988334,0.0025258174,0.0004123335,0.000086686516,0.99385643],"study_design_scores_gemma":[0.002604748,0.001547738,0.0023231367,0.014721335,0.0008704319,0.0025398845,0.00011571391,0.00034946762,0.0072408067,0.004983987,0.9620217,0.00068104547],"about_ca_topic_score_codex":4.0108438e-7,"about_ca_topic_score_gemma":0.0000012986202,"teacher_disagreement_score":0.9931753,"about_ca_system_score_codex":0.00002074908,"about_ca_system_score_gemma":0.00013035836,"threshold_uncertainty_score":0.6119987},"labels":[],"label_agreement":null},{"id":"W2136685395","doi":"10.4021/jocmr2009.12.1275","title":"Font Size: Effect of Escitalopram on White Blood Cells in Patients With Major Depression","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Medicine Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Escitalopram; Medicine; Depression (economics); White blood cell; Internal medicine; Serotonin reuptake inhibitor; Major depressive disorder; Gastroenterology; Pharmacology; Antidepressant; Serotonin; Receptor","score_opus":0.05600297440607638,"score_gpt":0.43612482258047375,"score_spread":0.38012184817439737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136685395","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948524,0.00006521778,0.000005770157,0.002211067,0.00021468352,0.00035571837,0.0000015649297,0.000004820595,0.0022887052],"genre_scores_gemma":[0.9990528,0.00010795424,0.00007092867,0.00041250244,0.0002287535,0.0000013412457,2.1691301e-7,0.000011260765,0.0001142354],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9943956,0.0015311174,0.0011954356,0.00028241862,0.0022159761,0.00037943272],"domain_scores_gemma":[0.9887543,0.009942549,0.00046203533,0.0002791239,0.00025782033,0.00030419492],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.005818385,0.0001365795,0.0007086489,0.00036852717,0.00005006653,0.000012329474,0.0004940794,0.00012417394,0.000090405374],"category_scores_gemma":[0.024101736,0.00007026872,0.00011966002,0.00070138834,0.0004253303,0.00012052148,0.000047331134,0.0012043926,0.000008307037],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.032124337,0.007997478,0.65417117,0.00019183564,0.000045302517,0.00061573886,0.00032433076,0.00006081192,0.04286958,0.000055505236,0.0074591655,0.25408477],"study_design_scores_gemma":[0.0243283,0.052251607,0.8423346,0.0014076937,0.000020414524,0.000006918499,0.000031474494,0.000019774836,0.07889365,0.00031620776,0.00029301664,0.00009628873],"about_ca_topic_score_codex":0.000004526269,"about_ca_topic_score_gemma":0.0000025474,"teacher_disagreement_score":0.25398847,"about_ca_system_score_codex":0.000020315441,"about_ca_system_score_gemma":0.000111199544,"threshold_uncertainty_score":0.98411864},"labels":[],"label_agreement":null},{"id":"W2136812855","doi":"10.1038/npp.2012.191","title":"Candidate Genes Expression Profile Associated with Antidepressants Response in the GENDEP Study: Differentiating between Baseline ‘Predictors’ and Longitudinal ‘Targets’","year":2012,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":433,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Medical Research Council; Regione Lombardia; Ministero della Salute; Servier; European Commission; National Institute for Health and Care Research; King's College London; Eli Lilly and Company; Psychiatry Research Trust; South London and Maudsley NHS Foundation Trust; National Alliance for Research on Schizophrenia and Depression","keywords":"Escitalopram; Antidepressant; Internal medicine; Nortriptyline; Proinflammatory cytokine; FKBP5; Medicine; Neurotrophic factors; Glucocorticoid receptor; Endocrinology; Citalopram; Major depressive disorder; Oncology; Brain-derived neurotrophic factor; Tumor necrosis factor alpha; Glucocorticoid; Psychology; Receptor; Inflammation; Amygdala; Amitriptyline","score_opus":0.04129203917185755,"score_gpt":0.3167356951785351,"score_spread":0.2754436560066776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136812855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99792904,0.00017827826,0.000034243654,0.00022563309,0.0004886989,0.0009068064,0.00005753436,0.00009027058,0.000089486995],"genre_scores_gemma":[0.9987774,0.00005779317,0.000016144662,0.00077251997,0.00017608223,0.00010820313,0.000008360273,0.000038729875,0.000044768563],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99449,0.003543115,0.00033529507,0.0005869797,0.00037363253,0.000670958],"domain_scores_gemma":[0.99754274,0.0018320563,0.00019101173,0.00026124288,0.000025691967,0.00014728161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00096759805,0.00028022015,0.00029934244,0.0001805262,0.00030064423,0.000048753674,0.000381185,0.00008171276,0.0001258623],"category_scores_gemma":[0.0004997722,0.0001850038,0.000034254186,0.00046812993,0.00017512837,0.00025674843,0.00011062486,0.00046334078,0.000010345938],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011812744,0.00072693505,0.6378239,0.000006442957,0.000013458254,0.000094777206,0.0019211986,0.0000044073954,0.3574014,9.2793044e-7,0.00029165935,0.0005336676],"study_design_scores_gemma":[0.0035563777,0.00056403945,0.9681906,0.000013912229,0.000039413797,0.000024192377,0.00029634242,0.00012837243,0.026801508,0.0000040544087,0.00018345092,0.00019774617],"about_ca_topic_score_codex":0.000009880555,"about_ca_topic_score_gemma":0.000012982079,"teacher_disagreement_score":0.3305999,"about_ca_system_score_codex":0.000020177346,"about_ca_system_score_gemma":0.000024093793,"threshold_uncertainty_score":0.7544236},"labels":[],"label_agreement":null},{"id":"W2137583344","doi":"10.1016/j.pnpbp.2009.09.020","title":"Oxidative stress in tardive dyskinesia: Genetic association study and meta-analysis of NADPH quinine oxidoreductase 1 (NQO1) and Superoxide dismutase 2 (SOD2, MnSOD) genes","year":2009,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"U.S. National Library of Medicine; Canadian Institutes of Health Research; University of California, Irvine","keywords":"SOD2; Superoxide dismutase; Oxidative stress; Tardive dyskinesia; Genotype; Internal medicine; Allele; Single-nucleotide polymorphism; Gene polymorphism; Medicine; Genetics; Biology; Gene; Schizophrenia (object-oriented programming); Psychiatry","score_opus":0.03803219227994182,"score_gpt":0.3340248728294256,"score_spread":0.2959926805494838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137583344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98643374,0.009143904,0.0000027370545,0.0030068527,0.00022072454,0.00096278545,0.00017043788,0.000036607926,0.00002222715],"genre_scores_gemma":[0.99605083,0.00147135,0.00024142484,0.0020474275,0.000041993095,0.000116268966,0.000012145409,0.0000104417095,0.000008141456],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9963546,0.0011186121,0.0006901141,0.0011470986,0.00022256986,0.00046702084],"domain_scores_gemma":[0.9986675,0.00062167825,0.0003217474,0.00020005098,0.000039167622,0.0001498597],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004060333,0.00039138523,0.0011140202,0.00050838315,0.000116248164,0.000038331702,0.0002648617,0.000248381,0.0000846679],"category_scores_gemma":[0.00019490386,0.00028482656,0.0001762442,0.0011644105,0.0005066915,0.00013579027,0.00011843936,0.0004358576,8.481058e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086797244,0.0026350508,0.9824025,0.000020148715,0.0016131642,0.00007886056,0.00035858565,0.000022930875,0.009916204,0.00010729513,0.00006101421,0.001916267],"study_design_scores_gemma":[0.0032526602,0.0012979272,0.9878707,0.00000259456,0.004909828,0.000008734577,0.00041394163,0.00012498794,0.0009103398,0.0008963538,0.000018084456,0.00029385823],"about_ca_topic_score_codex":0.000013129972,"about_ca_topic_score_gemma":0.000089184105,"teacher_disagreement_score":0.009617084,"about_ca_system_score_codex":0.000016858266,"about_ca_system_score_gemma":0.000021866254,"threshold_uncertainty_score":0.99996036},"labels":[],"label_agreement":null},{"id":"W2138112842","doi":"10.1111/j.1574-6968.2010.02034.x","title":"Histidine is a source of the antioxidant, α-ketoglutarate, in Pseudomonas fluorescens challenged by oxidative stress","year":2010,"lang":"en","type":"article","venue":"FEMS Microbiology Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University","funders":"Industry Canada","keywords":"Pseudomonas fluorescens; Biochemistry; Citric acid cycle; NAD+ kinase; Oxidative phosphorylation; Dehydrogenase; Oxidative stress; Biology; Reactive oxygen species; Metabolism; Isocitrate dehydrogenase; Enzyme; Chemistry; Bacteria","score_opus":0.010890831352446975,"score_gpt":0.22105825360795134,"score_spread":0.21016742225550436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138112842","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98913264,0.000054560012,0.000048116475,0.00958588,0.000480975,0.0003095586,0.00021066175,0.000036691257,0.00014089544],"genre_scores_gemma":[0.99275446,0.000027964676,0.000063924475,0.006778853,0.000035938658,0.000012536138,0.000009941818,0.000023194707,0.00029318756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984267,0.00023452872,0.00030564444,0.00052229466,0.00007295997,0.00043787246],"domain_scores_gemma":[0.99910647,0.00020211923,0.00019857057,0.00043003165,0.00001932742,0.00004350635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012620277,0.00022950715,0.00027995667,0.00010913495,0.00010578253,0.000012442761,0.00066484633,0.00017302771,0.000116795294],"category_scores_gemma":[0.00018105558,0.00015469873,0.00010974063,0.00031362489,0.0010304118,0.00006755498,0.00015148366,0.0005860355,0.00003893008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003795572,0.0001378458,0.0027553854,0.000010945734,0.000007972893,0.000005414889,0.0009760003,0.0000058155483,0.98279154,0.00005229178,0.012985346,0.00023348168],"study_design_scores_gemma":[0.00082968746,0.000032877466,0.0053159026,0.000025839654,0.0000039265155,0.00002839353,0.000092447204,0.00001560434,0.9835144,0.000019128285,0.00992721,0.00019454418],"about_ca_topic_score_codex":0.00010905051,"about_ca_topic_score_gemma":0.00017149282,"teacher_disagreement_score":0.0036217975,"about_ca_system_score_codex":0.000022974766,"about_ca_system_score_gemma":0.000028782042,"threshold_uncertainty_score":0.63084316},"labels":[],"label_agreement":null},{"id":"W2138288344","doi":"10.3389/fnbeh.2011.00019","title":"Toward an Anti-Inflammatory Strategy for Depression","year":2011,"lang":"en","type":"article","venue":"Frontiers in Behavioral Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; National Alliance for Research on Schizophrenia and Depression","keywords":"Depression (economics); Psychology; Medicine; Economics","score_opus":0.14056887179474437,"score_gpt":0.32100423502612835,"score_spread":0.18043536323138398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138288344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98937035,0.000035025572,0.0071445624,0.00001810144,0.0021544194,0.00059541804,0.00003418081,0.00016271933,0.00048523702],"genre_scores_gemma":[0.9962275,0.000027279946,0.00306025,0.00041748577,0.000028895365,0.00007801128,0.000002040644,0.00003064903,0.00012788516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976613,0.00011378709,0.0003049475,0.00094784936,0.00033141434,0.0006407231],"domain_scores_gemma":[0.99921817,0.000019549849,0.00011090341,0.00041986562,0.00002387769,0.00020766022],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018259704,0.00023235094,0.00022175937,0.0002540938,0.00020928783,0.00008773234,0.00095632457,0.00010630994,0.000021025999],"category_scores_gemma":[0.00012385595,0.0002209256,0.00008057584,0.00049031444,0.00048204616,0.0010264599,0.000096354,0.00020851905,0.000005081693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016445798,0.0009870776,0.17864744,0.000025703672,2.6181263e-7,0.00016764396,0.0012663509,0.00010490427,0.78833795,0.00065225794,0.0011667636,0.028479174],"study_design_scores_gemma":[0.0013976701,0.0007712204,0.37969995,0.000027596792,0.000008903795,0.000033116823,0.00071566034,0.003717803,0.6091826,0.0024964174,0.0012576857,0.00069136836],"about_ca_topic_score_codex":0.00002193275,"about_ca_topic_score_gemma":0.0000075733647,"teacher_disagreement_score":0.20105249,"about_ca_system_score_codex":0.000035348592,"about_ca_system_score_gemma":0.00007937597,"threshold_uncertainty_score":0.90090847},"labels":[],"label_agreement":null},{"id":"W2139001568","doi":"10.6000/1927-5951.2014.04.04.4","title":"Improved Serotonergic Tone Contributes to the Mechanism of Action of St John’s Wort in Nicotine Withdrawn Mice","year":2014,"lang":"en","type":"article","venue":"Journal of Pharmacy and Nutrition Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Nicotine; Serotonergic; Corticosterone; Chemistry; Saline; Serotonin; Pharmacology; Abstinence; 5-Hydroxyindoleacetic acid; Internal medicine; Endocrinology; Medicine; Biochemistry; Psychiatry","score_opus":0.0388499978309111,"score_gpt":0.34024816491690385,"score_spread":0.30139816708599276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139001568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99392474,0.00025466955,0.0010039757,0.0042630085,0.00023827194,0.00022565814,0.0000078006315,0.0000035913758,0.000078282064],"genre_scores_gemma":[0.9986174,0.00049297,0.00019595922,0.0006134594,0.00005714338,0.0000054339953,1.476366e-7,0.0000026566595,0.000014806792],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885166,0.00015762883,0.00041961335,0.00013817132,0.0002952631,0.00013764341],"domain_scores_gemma":[0.9991105,0.00027925643,0.00039627307,0.000054885946,0.00010369726,0.00005537227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010633338,0.00007532477,0.00019830388,0.00025737743,0.00011396665,0.000038157188,0.00027495518,0.000019172787,0.000020404448],"category_scores_gemma":[0.00030919886,0.00004862518,0.00005109999,0.0006770613,0.00024678346,0.00036449832,0.000032423195,0.00012303902,4.7006404e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030677076,0.00019285912,0.00035355412,0.000040286497,0.000002708882,5.4784846e-7,0.0001670542,0.00003181175,0.9954391,0.0015823807,0.00018287628,0.0017000542],"study_design_scores_gemma":[0.0022554146,0.00039200552,0.0006651279,0.000103808285,0.000008348534,0.00002500498,0.0004795923,0.0022818262,0.9887213,0.0022976173,0.0027137632,0.0000561598],"about_ca_topic_score_codex":0.000030849707,"about_ca_topic_score_gemma":0.00003342366,"teacher_disagreement_score":0.0067177643,"about_ca_system_score_codex":0.000011341351,"about_ca_system_score_gemma":0.00004643216,"threshold_uncertainty_score":0.19828774},"labels":[],"label_agreement":null},{"id":"W2139284574","doi":"10.1016/j.biopsych.2011.10.001","title":"Relating the Effects of Prenatal Stress in Rodents to the Pathogenesis of Schizophrenia","year":2011,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Offspring; NMDA receptor; AMPA receptor; Glutamatergic; Glutamate receptor; Synapse; Neuroscience; Biology; Synaptic plasticity; Ontogeny; Schizophrenia (object-oriented programming); Receptor; Endocrinology; Psychology; Pregnancy; Psychiatry","score_opus":0.031922829899591124,"score_gpt":0.25145336799153367,"score_spread":0.21953053809194256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139284574","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978429,0.0003167535,0.000018455152,0.00018849644,0.00050185405,0.00033525017,0.000017112223,0.000016157097,0.000763015],"genre_scores_gemma":[0.9992624,0.000025073645,0.00032074083,0.00031468435,0.00003845845,0.000019566622,5.3605027e-7,0.000005124197,0.000013434449],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99899054,0.00024754068,0.00022933428,0.00023687312,0.00012458504,0.00017112562],"domain_scores_gemma":[0.999251,0.00033189144,0.00010706795,0.00026957688,0.000008949481,0.000031496344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014585622,0.00009683227,0.00013067342,0.000036167738,0.000058014713,0.0000043992104,0.00053051097,0.00007591309,0.000023084682],"category_scores_gemma":[0.00079334754,0.000044134056,0.00007409618,0.00031180077,0.00014981283,0.000025674946,0.00013374821,0.00012448178,0.000011258991],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00079827907,0.0010852311,0.581918,0.00021875952,0.000015337584,0.0000062721124,0.0018367072,0.00002777009,0.37692925,0.020358639,0.00028250267,0.016523255],"study_design_scores_gemma":[0.0004308487,0.0003151207,0.8987675,0.00010954487,0.000003395395,0.0000014980875,0.00019091865,0.000012210034,0.0977734,0.0022908961,0.000019777588,0.00008490576],"about_ca_topic_score_codex":0.000030432439,"about_ca_topic_score_gemma":0.00004511393,"teacher_disagreement_score":0.3168495,"about_ca_system_score_codex":0.000003688716,"about_ca_system_score_gemma":0.000016632752,"threshold_uncertainty_score":0.17997347},"labels":[],"label_agreement":null},{"id":"W2140263133","doi":"10.1021/ja067211+","title":"Exiguamine A, an Indoleamine-2,3-dioxygenase (IDO) Inhibitor Isolated from the Marine Sponge <i>Neopetrosia </i><i>exigua</i>","year":2006,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":125,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Exigua; Sponge; Indoleamine 2,3-dioxygenase; Stereochemistry; Biogenesis; In vitro; Skeleton (computer programming); Carbon skeleton; Tryptophan; Biochemistry; Botany; Spodoptera; Gene; Biology; Anatomy; Amino acid","score_opus":0.010170603584430398,"score_gpt":0.22959814904436515,"score_spread":0.21942754545993476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140263133","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99573976,0.00011592027,0.000077930825,0.003256075,0.0002532979,0.00014650554,0.000047708814,0.00004498361,0.00031783018],"genre_scores_gemma":[0.98760426,0.000075297394,0.00069414964,0.010111058,0.0012659153,0.0000035355638,0.000005891741,0.000043105025,0.00019677868],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99759907,0.00024006213,0.0006341926,0.00035623138,0.00070782774,0.00046260026],"domain_scores_gemma":[0.9976897,0.0005438854,0.0009597561,0.0005527563,0.000089075744,0.00016480751],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028065033,0.00030027752,0.000456811,0.000019853822,0.00023955021,0.00011763319,0.0013766537,0.00008526332,0.00008973125],"category_scores_gemma":[0.0003267911,0.00016654436,0.00068958534,0.0008547024,0.0009796249,0.00024531578,0.00034973543,0.00088282017,0.000013107235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021660158,0.00032698907,0.0011890186,0.0000033882588,0.000023394938,0.000012923558,0.00020692717,0.000020890027,0.96924156,0.00001891393,0.026932977,0.0018063865],"study_design_scores_gemma":[0.0013071798,0.000193514,0.018225841,0.000028091117,0.000030178822,0.0001010835,0.00046302404,0.00035280178,0.97081935,0.00064977206,0.0075512035,0.00027793602],"about_ca_topic_score_codex":0.00046771564,"about_ca_topic_score_gemma":0.000020542444,"teacher_disagreement_score":0.019381775,"about_ca_system_score_codex":0.00012986145,"about_ca_system_score_gemma":0.000093033916,"threshold_uncertainty_score":0.67914814},"labels":[],"label_agreement":null},{"id":"W2143110843","doi":"10.1503/jpn.100059","title":"Pharmacogenetics of antidepressant response","year":2011,"lang":"en","type":"review","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":179,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pharmacogenetics; Antidepressant; Medicine; Pharmacology; Psychology; Psychiatry; Biology; Genetics; Genotype; Gene; Anxiety","score_opus":0.08418545772601496,"score_gpt":0.3552512087428509,"score_spread":0.27106575101683594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143110843","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005048875,0.9912952,0.00006475264,0.000069742855,0.003073651,0.0001903971,0.000030802556,0.000009330334,0.0002172189],"genre_scores_gemma":[0.00255493,0.996573,0.00030230268,0.0003424101,0.000116335694,0.0000014611453,6.680008e-8,0.000025851452,0.00008369961],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972789,0.00063741487,0.0010144874,0.00039814162,0.0003922953,0.00027875678],"domain_scores_gemma":[0.99742585,0.00037596584,0.0016627633,0.00028451192,0.00004893504,0.00020196936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006783772,0.00030380045,0.00096511573,0.00043061355,0.000114412804,0.000042615164,0.00096859696,0.00012122917,0.00001939516],"category_scores_gemma":[0.0007105689,0.00021749668,0.0004232241,0.0006813419,0.0005664245,0.00021240296,0.00013432911,0.00051560876,0.0000031623954],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014614604,0.0019771939,0.0005902717,0.019006412,0.000042917833,0.00035410826,0.0003472351,0.000010618043,0.034628,0.0045453603,0.0039936863,0.93304276],"study_design_scores_gemma":[0.0004799121,0.0008115209,0.00055605045,0.0041170586,0.00021625281,0.00230813,0.000014112333,0.0000053077683,0.0023435385,0.00043219334,0.98835987,0.00035604363],"about_ca_topic_score_codex":5.5438124e-7,"about_ca_topic_score_gemma":2.437193e-7,"teacher_disagreement_score":0.9843662,"about_ca_system_score_codex":0.0000073804586,"about_ca_system_score_gemma":0.0005795266,"threshold_uncertainty_score":0.88692576},"labels":[],"label_agreement":null},{"id":"W2143606210","doi":"10.1186/1741-7015-9-40","title":"L-lysine as adjunctive treatment in patients with schizophrenia: a single-blinded, randomized, cross-over pilot study","year":2011,"lang":"en","type":"article","venue":"BMC Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Adlerbertska Research Foundation; Svenska Läkaresällskapet; Fondation pour la Recherche Médicale; H. Lundbeck A/S; Åhlén-stiftelsen; Vetenskapsrådet; Stanley Medical Research Institute; Lundbeckfonden; Fredrik och Ingrid Thurings Stiftelse; Stiftelsen Tornspiran","keywords":"Medicine; Schizophrenia (object-oriented programming); Lysine; Positive and Negative Syndrome Scale; Internal medicine; Adjunctive treatment; Placebo; Randomized controlled trial; Gastroenterology; Psychosis; Psychiatry; Amino acid; Pathology","score_opus":0.08105561123731189,"score_gpt":0.29674725511520905,"score_spread":0.21569164387789716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143606210","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914451,0.0000573729,0.00008258906,0.00004270126,0.00024901042,0.0026435396,0.000006040398,0.00007705214,0.005396569],"genre_scores_gemma":[0.9986444,0.0000072756266,0.00012703096,0.00040578135,0.00008082723,0.00018600104,0.0000064125757,0.000034827903,0.0005074391],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9974848,0.00038336302,0.0004722277,0.00069640187,0.00059429504,0.0003689332],"domain_scores_gemma":[0.9985913,0.0005391014,0.00019161683,0.00046106832,0.00006690638,0.00014999454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031630302,0.0003477062,0.0007515596,0.0002872368,0.00009350835,0.000020431868,0.00023734616,0.000039898267,0.00071536005],"category_scores_gemma":[0.0013372159,0.00019803522,0.000056445868,0.0005920559,0.0006055891,0.00018657376,0.00005365474,0.00014492242,0.000069545255],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.7437008,0.015207028,0.2314381,0.000019323108,0.00007401915,0.00009525029,0.0057915957,0.000009577615,0.0008084326,0.000524971,0.000058062316,0.0022728597],"study_design_scores_gemma":[0.62649554,0.01804449,0.35292462,0.00006435068,0.00006813108,0.000002908532,0.00033259072,0.000021282598,0.0013991364,0.00039873,0.000021490501,0.00022677127],"about_ca_topic_score_codex":0.0012459945,"about_ca_topic_score_gemma":0.0011289011,"teacher_disagreement_score":0.12148651,"about_ca_system_score_codex":0.00010749209,"about_ca_system_score_gemma":0.00009125948,"threshold_uncertainty_score":0.8075642},"labels":[],"label_agreement":null},{"id":"W2144107861","doi":"10.1093/schbul/sbu099","title":"Towards a Psychosis Risk Blood Diagnostic for Persons Experiencing High-Risk Symptoms: Preliminary Results From the NAPLS Project","year":2014,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":238,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; University of Calgary","funders":"National Institute of Mental Health","keywords":"Prodrome; Psychosis; Medicine; Internal medicine; Psychology; Psychiatry; Clinical psychology","score_opus":0.014657814417000935,"score_gpt":0.2434265354076448,"score_spread":0.22876872099064388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144107861","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98910636,0.00030072802,0.00089931465,0.004375381,0.00076153694,0.0015834573,0.0020977322,0.0003457094,0.00052980677],"genre_scores_gemma":[0.99210954,0.00029363236,0.0044682734,0.0011909342,0.0007175958,0.0008724935,0.00004456605,0.00008591326,0.00021706671],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960726,0.00081851374,0.00055004103,0.0013131681,0.00051267695,0.00073299353],"domain_scores_gemma":[0.9892783,0.009021266,0.0004352662,0.0010591988,0.00005377237,0.00015218892],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007085888,0.00046121268,0.00038490878,0.000111995716,0.0010205263,0.00023342673,0.0010451068,0.00018766707,0.00014437152],"category_scores_gemma":[0.02330501,0.00033506166,0.0002994806,0.00040537416,0.00032921004,0.00008764779,0.00019774093,0.0005272457,0.00016677644],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.04076345,0.003222313,0.0033542968,0.00017549883,0.0005569197,0.00007362789,0.071767636,0.0005150447,0.02415155,0.0067336606,0.52698326,0.32170278],"study_design_scores_gemma":[0.08508092,0.013911766,0.08306516,0.0015177381,0.0018260976,0.000104086685,0.012590499,0.0053789467,0.25524423,0.016071042,0.51940227,0.0058072736],"about_ca_topic_score_codex":0.002567136,"about_ca_topic_score_gemma":0.0001409352,"teacher_disagreement_score":0.3158955,"about_ca_system_score_codex":0.00003141049,"about_ca_system_score_gemma":0.00009564361,"threshold_uncertainty_score":0.9999101},"labels":[],"label_agreement":null},{"id":"W2146026881","doi":"10.1186/1742-2094-8-17","title":"The relationship between indoleamine 2,3-dioxygenase activity and post-stroke cognitive impairment","year":2011,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Heart and Stroke Foundation; Health Sciences Centre; Institute for Clinical Evaluative Sciences; Sunnybrook Health Science Centre","funders":"Alzheimer Society; Heart and Stroke Foundation of Canada","keywords":"Indoleamine 2,3-dioxygenase; Neurology; Stroke (engine); Cognition; Cognitive impairment; Neuroscience; Medicine; Neuroinflammation; Psychiatry; Psychology; Immunology; Biology; Inflammation; Biochemistry","score_opus":0.059534400473146946,"score_gpt":0.2750771259304739,"score_spread":0.21554272545732694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146026881","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99863905,0.000025174846,0.0001414631,0.00046868203,0.000103449594,0.00017814098,0.000010699076,0.000013131082,0.00042024167],"genre_scores_gemma":[0.99965346,0.000034115455,0.00003621275,0.00004368871,0.00010072246,0.0000019373344,4.3669704e-7,0.000009705297,0.00011971378],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989108,0.00025985087,0.00030004737,0.00011594803,0.00027043934,0.00014290822],"domain_scores_gemma":[0.9979522,0.0013156551,0.00046269735,0.00009023159,0.000092211354,0.0000869601],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034582042,0.00009749306,0.00011232084,0.000117746196,0.0002489674,0.00005862973,0.00012433174,0.000039594503,0.000007996241],"category_scores_gemma":[0.0025902318,0.000067318826,0.000068296235,0.000118304575,0.00010780796,0.00048205437,0.00003534877,0.0002764857,0.000011331019],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060403097,0.000107023414,0.021302884,0.000022709439,0.000015571595,0.00005835106,0.0016528422,0.000002780399,0.949671,0.00064331293,0.000046665056,0.025872847],"study_design_scores_gemma":[0.00053542596,0.00031871072,0.6723103,0.000016332004,0.000007587915,0.00006725759,0.00011619327,0.00002332947,0.32594007,0.0005977668,0.000017585577,0.000049443068],"about_ca_topic_score_codex":0.0000034059167,"about_ca_topic_score_gemma":0.0000049622004,"teacher_disagreement_score":0.6510074,"about_ca_system_score_codex":0.00001808749,"about_ca_system_score_gemma":0.000044350763,"threshold_uncertainty_score":0.31009367},"labels":[],"label_agreement":null},{"id":"W2146888659","doi":"10.1155/2016/4729192","title":"Redox Modulations, Antioxidants, and Neuropsychiatric Disorders","year":2015,"lang":"en","type":"review","venue":"Oxidative Medicine and Cellular Longevity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Perspective (graphical); Redox; Neuroscience; Review article; Medicine; Psychology; Bioinformatics; Biology; Computer science; Chemistry; Pathology","score_opus":0.06828598713122698,"score_gpt":0.3269055788100485,"score_spread":0.25861959167882154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146888659","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014636643,0.992872,0.00029394682,0.00034198616,0.00038128515,0.00095680775,0.00005043747,0.00008611837,0.0035537528],"genre_scores_gemma":[0.002036751,0.9966205,0.00006113126,0.00020359621,0.0002544454,0.000034719218,0.000064814354,0.00006602798,0.0006580096],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99666214,0.00078434095,0.0005799418,0.0011078981,0.00046758298,0.00039807725],"domain_scores_gemma":[0.9982728,0.00043147887,0.0004204836,0.0005048589,0.000043232558,0.00032719792],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050336466,0.00063236355,0.0015702787,0.00039555738,0.00025430875,0.0000505161,0.00030469015,0.0002314683,0.000089671026],"category_scores_gemma":[0.0008200334,0.00045755116,0.00015006226,0.00089871883,0.0008603629,0.00019869763,0.0002097852,0.0005667485,0.000038986134],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008416207,0.00008927296,0.000031925967,0.0031986553,0.000025570285,0.000027995076,0.00021148763,1.4501025e-7,0.00021054647,0.0011124085,0.0023345882,0.992749],"study_design_scores_gemma":[0.0006546184,0.00021016746,0.00007340993,0.00144821,0.00032688474,0.00004707012,0.000113374306,0.000027725437,0.000030482905,0.0012734906,0.9952801,0.00051448285],"about_ca_topic_score_codex":0.000036284084,"about_ca_topic_score_gemma":0.000012274344,"teacher_disagreement_score":0.9929455,"about_ca_system_score_codex":0.000031460393,"about_ca_system_score_gemma":0.00011606614,"threshold_uncertainty_score":0.9997876},"labels":[],"label_agreement":null},{"id":"W2147065314","doi":"10.1016/j.comppsych.2004.07.029","title":"A case of seasonal bipolar disorder exacerbated by Cushing's disease","year":2005,"lang":"en","type":"article","venue":"Comprehensive Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal General Hospital; Royal Victoria Hospital; McGill University Health Centre; Royal Victoria Regional Health Centre","funders":"","keywords":"Bipolar disorder; Light therapy; Hypercortisolemia; Medicine; Adrenocorticotropic hormone; Depression (economics); Lithium (medication); Internal medicine; Cushing syndrome; Endocrinology; Pediatrics; Mood; Psychiatry; Hydrocortisone; Hormone","score_opus":0.01827078760250602,"score_gpt":0.2642794858253308,"score_spread":0.24600869822282476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147065314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98388225,0.011129698,0.00032537934,0.0028855407,0.00059357536,0.00032193508,0.00025347547,0.00015888146,0.00044929137],"genre_scores_gemma":[0.99486893,0.00015172313,0.0006436379,0.0037638464,0.00015553595,0.000017202005,0.000016720327,0.000045126006,0.0003372892],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982171,0.00016571357,0.0003328411,0.0005837977,0.00028758775,0.00041293332],"domain_scores_gemma":[0.9987879,0.000170512,0.00016229192,0.00048195108,0.00008086371,0.000316491],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000038694303,0.00028234767,0.00026044896,0.00011067645,0.00021051812,0.000040885985,0.00033695722,0.00007885827,0.0004088739],"category_scores_gemma":[0.00012551504,0.0002713966,0.00018210441,0.00045415224,0.00028636848,0.00022948199,0.00011171158,0.00024171887,0.00013933009],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017401449,0.007438754,0.071296886,0.0009583142,0.00018406927,0.00093302253,0.0018778067,0.001648708,0.38056883,0.028115356,0.39881587,0.10642224],"study_design_scores_gemma":[0.009733026,0.00047543892,0.028515648,0.0002562236,0.00015327046,0.0013852415,0.0016116899,0.015152149,0.02600308,0.0055628223,0.90870136,0.002450042],"about_ca_topic_score_codex":0.000029658038,"about_ca_topic_score_gemma":0.00003463782,"teacher_disagreement_score":0.5098855,"about_ca_system_score_codex":0.000021605296,"about_ca_system_score_gemma":0.00011739298,"threshold_uncertainty_score":0.99997383},"labels":[],"label_agreement":null},{"id":"W2147141656","doi":"10.1007/s12575-010-9028-6","title":"Highly Efficient Stable Expression of Indoleamine 2,3 Dioxygenase Gene in Primary Fibroblasts","year":2010,"lang":"en","type":"article","venue":"Biological Procedures Online","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Indoleamine 2,3-dioxygenase; Cell sorting; Gene expression; Transfection; Population; Cell biology; Biology; Immune system; Transplantation; Inducer; Regulation of gene expression; Cancer research; Gene; Molecular biology; Chemistry; Immunology; Flow cytometry; Genetics; Medicine","score_opus":0.02226370948116194,"score_gpt":0.25636468020754594,"score_spread":0.234100970726384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147141656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99877083,0.00013617192,0.00003985608,0.0001471472,0.00010554226,0.0003207149,0.00011128868,0.000082076855,0.00028639843],"genre_scores_gemma":[0.997586,0.000059027352,0.0016002681,0.00051606965,0.00008087397,0.000016978465,0.0000444516,0.0000126930245,0.00008363833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845564,0.00007727388,0.000376222,0.000513157,0.00022032725,0.00035740453],"domain_scores_gemma":[0.99924296,0.00023505594,0.00013273972,0.0002508951,0.000032056043,0.00010626687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001391394,0.00019173646,0.00027728942,0.00011680301,0.000052009895,0.000011863558,0.00037822244,0.00019850985,0.00008587599],"category_scores_gemma":[0.0017367979,0.00012615693,0.00006674023,0.00036191175,0.00025656633,0.000050572165,0.00020173134,0.00033156946,0.000012215655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023933098,0.0011942845,0.000568466,0.000059554262,7.1567376e-7,0.000011710252,0.000038783324,0.00014998188,0.9969348,0.00012870273,0.00012830547,0.00054536964],"study_design_scores_gemma":[0.0008050871,0.00021792151,0.06011378,0.00004571299,5.095947e-7,0.000008537796,0.000021713988,0.00019256303,0.9378813,0.00015794863,0.00039027818,0.00016467762],"about_ca_topic_score_codex":0.000006689833,"about_ca_topic_score_gemma":0.000027376936,"teacher_disagreement_score":0.059545312,"about_ca_system_score_codex":0.000016781174,"about_ca_system_score_gemma":0.00008263229,"threshold_uncertainty_score":0.514453},"labels":[],"label_agreement":null},{"id":"W2148598875","doi":"10.1016/j.schres.2008.10.003","title":"Prenatal immune challenge induces developmental changes in the morphology of pyramidal neurons of the prefrontal cortex and hippocampus in rats","year":2008,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":113,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Prefrontal cortex; Dendritic spine; Hippocampal formation; Hippocampus; Offspring; Neuroscience; Immune system; Fetus; Biology; Internal medicine; Endocrinology; Medicine; Immunology; Pregnancy","score_opus":0.07192941418791407,"score_gpt":0.3073849140628853,"score_spread":0.23545549987497125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148598875","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967277,0.0005504501,1.08242546e-7,0.0013965678,0.0000823807,0.00059574057,0.000020172016,0.000007592512,0.00061926723],"genre_scores_gemma":[0.99940395,0.00038331145,0.000032295233,0.000062355386,0.00001782997,0.0000402097,0.0000015032302,0.000012688121,0.000045872846],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.997466,0.0008307869,0.00027813495,0.0003654314,0.00062009064,0.00043950972],"domain_scores_gemma":[0.99899656,0.000572393,0.00007667383,0.0002842694,0.000030813415,0.000039279566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006315499,0.00013199143,0.00021296651,0.00029837035,0.00017133274,0.000012917884,0.00081162684,0.000096518655,0.00002975585],"category_scores_gemma":[0.00056140317,0.0000846242,0.00003598036,0.0007944698,0.0016972235,0.00010013966,0.0004662533,0.000697996,0.000004449951],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008236474,0.00047762625,0.00487499,0.00007499159,0.000005125135,0.000117492076,0.008475349,0.0000027937974,0.97738326,0.0013045648,0.00004560228,0.0064145783],"study_design_scores_gemma":[0.0013637113,0.00019784967,0.714133,0.00005401018,8.180109e-7,0.000120046214,0.0013593454,0.000027664204,0.2815252,0.001114787,0.000015714748,0.00008780825],"about_ca_topic_score_codex":0.00025407545,"about_ca_topic_score_gemma":0.0017765453,"teacher_disagreement_score":0.7092581,"about_ca_system_score_codex":0.000033032687,"about_ca_system_score_gemma":0.0002417099,"threshold_uncertainty_score":0.6253491},"labels":[],"label_agreement":null},{"id":"W2149240801","doi":"10.1177/0269881113490329","title":"ATP-binding cassette sub-family F member 1 (ABCF1) is identified as a putative therapeutic target of escitalopram in the inflammatory cytokine pathway","year":2013,"lang":"en","type":"article","venue":"Journal of Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Escitalopram; Major depressive disorder; Antidepressant; Proinflammatory cytokine; Cytokine; Transcriptome; Medicine; Internal medicine; Pharmacology; Oncology; Bioinformatics; Immunology; Biology; Inflammation; Gene expression; Gene; Genetics; Amygdala","score_opus":0.03162534028473807,"score_gpt":0.3207008437798483,"score_spread":0.28907550349511024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149240801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933063,0.0003695312,0.000045894165,0.00316962,0.0012808784,0.00047116465,0.00001586283,0.00001193829,0.0013288286],"genre_scores_gemma":[0.9882035,0.00019964635,0.00006922293,0.01121381,0.00014546323,0.000029179755,7.0048316e-7,0.000026067955,0.00011239033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99725246,0.0006653671,0.00086376816,0.000278082,0.0005242956,0.00041604176],"domain_scores_gemma":[0.99793977,0.00076974195,0.00084152905,0.0001858922,0.00015656235,0.00010651432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00076445204,0.00022998288,0.00040293086,0.00042707563,0.00009406986,0.00006151515,0.0007341912,0.0001277688,0.00076016743],"category_scores_gemma":[0.0001603906,0.00016104785,0.00021458266,0.00061737973,0.00029492643,0.0005027842,0.0000498723,0.0006805571,0.0001688394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028849771,0.00029049828,0.0007248591,0.000023980805,0.00005612877,0.000211455,0.0053941477,0.000049113893,0.98408747,0.0001311335,0.0076530864,0.0010896225],"study_design_scores_gemma":[0.0072790766,0.0007099662,0.048146944,0.000056699046,0.000055266817,0.00050468143,0.0034659216,0.00022061353,0.9179589,0.0103192665,0.010908787,0.00037384304],"about_ca_topic_score_codex":0.00001732402,"about_ca_topic_score_gemma":0.0000037006193,"teacher_disagreement_score":0.066128545,"about_ca_system_score_codex":0.00005804273,"about_ca_system_score_gemma":0.00015377675,"threshold_uncertainty_score":0.83233},"labels":[],"label_agreement":null},{"id":"W2149858560","doi":"10.1038/npp.2014.226","title":"Testing the Predictive Value of Peripheral Gene Expression for Nonremission Following Citalopram Treatment for Major Depression","year":2014,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"National Institute of Mental Health; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Citalopram; Major depressive disorder; Cohort; Internal medicine; Medicine; Depression (economics); Prospective cohort study; Oncology; Antidepressant","score_opus":0.03734421012877817,"score_gpt":0.32457649490582663,"score_spread":0.28723228477704843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149858560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97820413,0.00007867674,0.01665102,0.00034717325,0.0017400819,0.0018600128,0.000042950454,0.000104748746,0.00097120064],"genre_scores_gemma":[0.9935995,0.0000124953895,0.0039854855,0.001255018,0.0003163709,0.0005925923,0.000005800465,0.00005004164,0.00018273122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981053,0.0003405339,0.0003289743,0.00063236477,0.00018105151,0.00041178483],"domain_scores_gemma":[0.99687064,0.0024751564,0.00022222637,0.00027302606,0.000055360502,0.00010359538],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020768718,0.00024204372,0.00027237946,0.00006779051,0.00042651722,0.000022505468,0.00036136943,0.000100892205,0.000019206796],"category_scores_gemma":[0.0010882288,0.00015934986,0.00023320467,0.00019039083,0.00010760024,0.00010439236,0.00006403305,0.00011360247,0.0000021167368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011243096,0.00023508233,0.00038631607,0.000025350253,0.00001150241,0.000002490381,0.00020802025,0.00048407054,0.9794342,0.000035500976,0.0009893007,0.017063849],"study_design_scores_gemma":[0.0065345922,0.0015874802,0.003446465,0.000030963005,0.0000579321,0.000012128834,0.000031265117,0.024068715,0.9572607,0.0005210593,0.0062832055,0.00016546783],"about_ca_topic_score_codex":0.0000035982034,"about_ca_topic_score_gemma":3.5896946e-7,"teacher_disagreement_score":0.023584643,"about_ca_system_score_codex":0.000037517253,"about_ca_system_score_gemma":0.000043328266,"threshold_uncertainty_score":0.6498099},"labels":[],"label_agreement":null},{"id":"W2153441220","doi":"10.1073/pnas.1119283109","title":"Reply to McLean et al. and Burnet: The microbiome–gut–brain axis as a pathway toward next generation psychotropics","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Task (project management); Computer science; Perception; Artificial intelligence; Cognitive science; Visual perception; Computer vision; Human–computer interaction; Cognitive psychology; Psychology; Neuroscience","score_opus":0.1013482793335116,"score_gpt":0.332001675998114,"score_spread":0.23065339666460238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153441220","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84804773,0.00012708714,0.0000027389997,0.1483001,0.000057046756,0.00024973744,0.000010696489,0.000013233629,0.00319162],"genre_scores_gemma":[0.9262605,0.000051161063,0.0005270819,0.07284256,0.00007948814,0.000011651929,8.6964214e-8,0.000004987568,0.00022251527],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845475,0.00002255595,0.0002398757,0.0002996595,0.00076610316,0.00021705816],"domain_scores_gemma":[0.9994386,0.00017386748,0.00022356397,0.00001568131,0.000084546286,0.00006374449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001289537,0.00010449294,0.000100753576,0.00013018388,0.0002840766,0.000090140966,0.00069294905,0.00004313974,0.000018106108],"category_scores_gemma":[0.0014990419,0.000060864135,0.00005019577,0.00081785826,0.00069546694,0.00071429723,0.00014877936,0.00014625522,0.000006082854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008333024,0.000034071545,0.00024863545,0.0000087210465,0.0000019267475,2.1575708e-9,0.0012308863,0.000006214172,0.91697544,0.05683141,0.023843696,0.00081069046],"study_design_scores_gemma":[0.0001816412,0.00008699736,0.013660736,0.000029953018,0.000002434187,0.000022049793,0.00048653368,0.00025852513,0.91350365,0.0113450745,0.06030047,0.00012192811],"about_ca_topic_score_codex":0.0000082945535,"about_ca_topic_score_gemma":9.5702205e-8,"teacher_disagreement_score":0.07821273,"about_ca_system_score_codex":0.00001757525,"about_ca_system_score_gemma":0.000025676856,"threshold_uncertainty_score":0.2562477},"labels":[],"label_agreement":null},{"id":"W2153574969","doi":"10.1016/j.bbi.2013.09.014","title":"Inflammatory dietary pattern and risk of depression among women","year":2013,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":216,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Depression (economics); Confounding; Medicine; Internal medicine; Body mass index; Confidence interval; Antidepressant; Prospective cohort study; Relative risk","score_opus":0.014792197818250275,"score_gpt":0.23618736269898952,"score_spread":0.22139516488073924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153574969","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99931455,0.00009624608,0.0000069780185,0.000022815295,0.000058989568,0.0002665779,0.000015923913,0.00003558753,0.00018233553],"genre_scores_gemma":[0.9994253,0.00020313475,0.000011833481,0.00011402762,0.000007974839,0.000065863205,0.0000019431834,0.000011676506,0.0001582658],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990889,0.00022694386,0.0001724507,0.00019509239,0.00011475078,0.00020185714],"domain_scores_gemma":[0.9993204,0.00020843478,0.000096415395,0.00025464807,0.0000167676,0.000103372826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015240809,0.00012044438,0.00014408237,0.00006183019,0.00018267524,0.000037598587,0.00013806499,0.000069121736,0.00015875907],"category_scores_gemma":[0.00019321292,0.00010156598,0.00002862012,0.00007214161,0.00033594057,0.00028596824,0.00018086463,0.00020911921,0.0000065505037],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000071945265,0.000083129904,0.70404655,0.000018721517,0.000002108191,0.0000018895117,0.0010124566,1.5433511e-7,0.21779388,0.0000014926014,0.00009768993,0.07693471],"study_design_scores_gemma":[0.00044959396,0.00006798405,0.9690108,0.000017220833,0.0000073675933,0.000004221401,0.00065165455,0.000027473976,0.029508397,0.00008663088,0.000050673956,0.00011801034],"about_ca_topic_score_codex":0.00080446474,"about_ca_topic_score_gemma":0.000025669138,"teacher_disagreement_score":0.2649642,"about_ca_system_score_codex":0.000007807793,"about_ca_system_score_gemma":0.000008449421,"threshold_uncertainty_score":0.41417405},"labels":[],"label_agreement":null},{"id":"W2153868934","doi":"10.1080/15476910802085723","title":"Changes in Gene Expression Induced by Carbamazepine and Phenytoin: Testing the Danger Hypothesis","year":2008,"lang":"en","type":"article","venue":"Journal of Immunotoxicology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Oxidative stress; Carbamazepine; Immune system; Pharmacology; Metabolite; Phenytoin; Chemistry; Biology; Biochemistry; Immunology; Epilepsy","score_opus":0.06855938810225783,"score_gpt":0.25969529486102605,"score_spread":0.19113590675876824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153868934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968016,0.00080342195,0.000007669092,0.001840642,0.0001794748,0.00012250902,0.000002149192,0.000008387603,0.00023415974],"genre_scores_gemma":[0.9973602,0.00048120643,0.0003727126,0.0016299413,0.00007854833,0.0000077811155,1.0813891e-7,0.000013271443,0.000056178727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988906,0.00026317482,0.00029622964,0.0001484488,0.00016624454,0.00023533175],"domain_scores_gemma":[0.9985165,0.0009679039,0.000299721,0.00013448423,0.000035783003,0.000045586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027308284,0.00011591202,0.00023239225,0.00013527593,0.00015437906,0.000015872107,0.00027826428,0.000093931405,0.00003172523],"category_scores_gemma":[0.0017474857,0.00007515691,0.000035611665,0.00025487697,0.0001819864,0.00010604705,0.00007929192,0.00033632794,0.0000026172609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006118972,0.000084597814,0.0006006879,0.000003343595,0.0000032655091,0.00006265429,0.000568507,0.0000033561014,0.9925531,0.0000033428846,0.000476438,0.0055794767],"study_design_scores_gemma":[0.00093952543,0.00035771538,0.028376698,0.000027257716,0.0000032928301,0.00081246695,0.00014128129,0.000025764695,0.9683247,0.00009214958,0.0008096678,0.000089483525],"about_ca_topic_score_codex":0.000008494505,"about_ca_topic_score_gemma":0.000008086233,"teacher_disagreement_score":0.02777601,"about_ca_system_score_codex":0.000033055163,"about_ca_system_score_gemma":0.00005229365,"threshold_uncertainty_score":0.306481},"labels":[],"label_agreement":null},{"id":"W2154558110","doi":"10.1016/j.euroneuro.2011.07.002","title":"The keys to improving depression outcomes","year":2011,"lang":"en","type":"review","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"British Association for Psychopharmacology","keywords":"Tolerability; Monoamine neurotransmitter; Antidepressant; Depression (economics); Neuroscience; Psychology; Agomelatine; Medicine; Psychiatry; Pharmacology; Internal medicine; Anxiety; Serotonin; Receptor; Adverse effect","score_opus":0.06598592553186904,"score_gpt":0.3548013391566907,"score_spread":0.28881541362482166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154558110","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000171138,0.9469197,0.00003188881,0.00018187807,0.007515959,0.0019024863,0.000026459644,0.00085123704,0.04239926],"genre_scores_gemma":[0.00023673754,0.98827255,0.000034067558,0.006136768,0.0004367315,0.00012695817,0.0000025139611,0.00047621343,0.0042774393],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99233586,0.0039017787,0.00094540534,0.0015405546,0.00027434595,0.0010020611],"domain_scores_gemma":[0.99638796,0.0014941334,0.0005602244,0.0011209479,0.000032952736,0.0004037555],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00051668234,0.0008342715,0.0010808883,0.0003034512,0.0005754542,0.00017344032,0.002881571,0.00013335787,0.00018420673],"category_scores_gemma":[0.0010083632,0.0005105788,0.00064160686,0.0006965078,0.00027293098,0.000099706784,0.0009995989,0.0008965282,0.005362212],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003610303,0.00008288561,0.0000016152723,0.0004041909,0.000021839882,0.0002747621,0.000057378027,3.9935617e-7,0.0025660656,0.00013127204,0.01561262,0.9808109],"study_design_scores_gemma":[0.00043702955,0.000111804504,0.00014951716,0.00024079201,0.000119881086,0.00010499535,0.0000036782649,0.0000012680032,0.00005046689,0.000014306177,0.9982476,0.000518643],"about_ca_topic_score_codex":0.0000029116038,"about_ca_topic_score_gemma":0.0000015401978,"teacher_disagreement_score":0.982635,"about_ca_system_score_codex":0.0000427555,"about_ca_system_score_gemma":0.00009046707,"threshold_uncertainty_score":0.9997346},"labels":[],"label_agreement":null},{"id":"W2155488925","doi":"10.1177/0269881113512043","title":"Tryptophan and inhibitors of tryptophan 2,3-dioxygenase as antidepressants","year":2014,"lang":"en","type":"letter","venue":"Journal of Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Cardiff Metropolitan University; Cardiff University","keywords":"Tryptophan; Tryptophan Metabolism; Pharmacology; Indoleamine 2,3-dioxygenase; Medicine; Chemistry; Biochemistry; Amino acid","score_opus":0.024414575277270204,"score_gpt":0.31048613092513716,"score_spread":0.28607155564786696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155488925","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8424123,0.0023501264,0.000054519223,0.14408208,0.007399362,0.0005436121,0.00005678295,0.000047356607,0.0030538281],"genre_scores_gemma":[0.48517585,0.0024872036,0.00018146833,0.5047845,0.0065530105,0.000010410577,0.000003862531,0.00013028152,0.0006733737],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99537516,0.00087316683,0.0015571745,0.00067643967,0.00082662544,0.0006914435],"domain_scores_gemma":[0.9957797,0.0009514448,0.0023997345,0.00038702117,0.00020356671,0.00027853515],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00047650348,0.0005987816,0.0013659701,0.0009571866,0.00011655966,0.000054751392,0.0010171366,0.0009836266,0.0007952517],"category_scores_gemma":[0.00049364567,0.00052092,0.00050206034,0.00042358233,0.0006680898,0.0002519809,0.0001246367,0.0026592757,0.00005341313],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044462964,0.0001370247,0.0000335401,0.00020965433,0.000085326414,0.0011657652,0.00013790444,0.000004433879,0.35907346,0.000021161137,0.6369359,0.0017511926],"study_design_scores_gemma":[0.0071220635,0.0012218143,0.00034823886,0.00022193954,0.00013934402,0.0024078526,0.000047565947,0.00001652073,0.3449853,0.0019605656,0.6409382,0.0005905859],"about_ca_topic_score_codex":0.000010867284,"about_ca_topic_score_gemma":8.4559287e-7,"teacher_disagreement_score":0.36070246,"about_ca_system_score_codex":0.00004639787,"about_ca_system_score_gemma":0.00021474402,"threshold_uncertainty_score":0.9997242},"labels":[],"label_agreement":null},{"id":"W2156443184","doi":"10.1093/schbul/sbu157","title":"Imaging Neuroinflammation in Gray and White Matter in Schizophrenia: An In-Vivo PET Study With [18F]-FEPPA","year":2014,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":169,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute of Mental Health","keywords":"Translocator protein; Neuroinflammation; White matter; Positron emission tomography; Radioligand; Magnetic resonance imaging; Binding potential; Medicine; Imaging biomarker; Psychology; In vivo; Nuclear medicine; Pathology; Internal medicine; Radiology; Receptor; Inflammation; Biology","score_opus":0.007245024041339829,"score_gpt":0.2194012292938617,"score_spread":0.21215620525252185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156443184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947278,0.000017714208,0.000022754222,0.0028179788,0.0000991397,0.0007614624,0.0000048268303,0.00008424453,0.0014641073],"genre_scores_gemma":[0.9982496,0.0000080606205,0.0006726421,0.0007578747,0.000057786416,0.00007953968,0.0000027453882,0.00005999685,0.000111752364],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99681675,0.00068287336,0.0005186169,0.001029738,0.00037427482,0.0005777643],"domain_scores_gemma":[0.9990235,0.0001743244,0.00013939368,0.00050952047,0.00002066365,0.00013258196],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00059103343,0.000375859,0.00038891856,0.00068920327,0.00010740394,0.00021045844,0.0003758001,0.000044479468,0.00033338615],"category_scores_gemma":[0.00019901016,0.00034191247,0.00003183504,0.0007201723,0.0001696514,0.000317192,0.000136427,0.00053971924,0.00015158587],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00456161,0.0010608865,0.9478205,0.00007878841,0.0000038433386,0.0007561007,0.0020850298,0.0006559393,0.036555473,0.0008459714,0.0006313424,0.0049445215],"study_design_scores_gemma":[0.011954438,0.00037544104,0.98031205,0.00012924666,0.000005900857,0.00012852377,0.00068708445,0.0018276703,0.0024236683,0.00078485685,0.0007299159,0.0006412163],"about_ca_topic_score_codex":0.00021566954,"about_ca_topic_score_gemma":0.003868003,"teacher_disagreement_score":0.034131803,"about_ca_system_score_codex":0.000040710453,"about_ca_system_score_gemma":0.000040264033,"threshold_uncertainty_score":0.99990326},"labels":[],"label_agreement":null},{"id":"W2156920421","doi":"10.1176/appi.ajp.2014.14070926r","title":"Response to Kunte et al.","year":2015,"lang":"en","type":"letter","venue":"American Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Depression (economics); Nortriptyline; Medicine; Biomarker; Internal medicine; Cohort; Psychology; Psychiatry; Biology","score_opus":0.020412020618102975,"score_gpt":0.3005835055486451,"score_spread":0.2801714849305421,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156920421","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.026221456,0.00016131117,0.0002485117,0.9678589,0.0039311983,0.00012256758,0.00004351853,0.0000325203,0.0013799903],"genre_scores_gemma":[0.003452256,0.000050403265,0.003921249,0.9898189,0.0014047753,0.0000031472107,0.0000016180358,0.000086976455,0.0012607106],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99632317,0.0011269693,0.0006296671,0.00041782687,0.0010264392,0.00047590374],"domain_scores_gemma":[0.99752975,0.00045136132,0.0010830661,0.0004959428,0.00014275651,0.0002971259],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009240126,0.00034719182,0.000629117,0.0006095714,0.00005977179,0.00009183974,0.0010620866,0.00012202991,0.00010012472],"category_scores_gemma":[0.0009767218,0.00029257845,0.0003367092,0.0007370446,0.00040742237,0.00014619358,0.00008452939,0.002202719,0.00026067288],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009369405,0.000052683692,0.00005416309,0.0000060640673,0.000021043812,0.00027056664,0.00020464379,0.0000098391565,0.0019545278,0.00002880389,0.9943671,0.0020936227],"study_design_scores_gemma":[0.0005164931,0.001815349,0.0001713132,0.00012737999,0.000016595264,0.0006260363,0.00028655116,8.713716e-7,0.00014596783,0.0006560798,0.9952996,0.0003378098],"about_ca_topic_score_codex":0.000012036554,"about_ca_topic_score_gemma":0.0000045890297,"teacher_disagreement_score":0.022769202,"about_ca_system_score_codex":0.000080000485,"about_ca_system_score_gemma":0.0012002719,"threshold_uncertainty_score":0.9999526},"labels":[],"label_agreement":null},{"id":"W2157130670","doi":"10.2147/ndt.s41020","title":"Effects of pentoxifylline, 7-nitroindazole, and imipramine on tumor necrosis factor-&amp;alpha; and indoleamine 2,3-dioxygenase enzyme activity in the hippocampus and frontal cortex of chronic mild-stress-exposed rats","year":2013,"lang":"en","type":"article","venue":"Neuropsychiatric Disease and Treatment","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"","keywords":"Pentoxifylline; Medicine; Endocrinology; Imipramine; Nitric oxide synthase; Hippocampus; Internal medicine; Enos; Tumor necrosis factor alpha; Serotonin; Nitric oxide; Immunostaining; Pharmacology; Immunohistochemistry; Pathology; Receptor","score_opus":0.013835055917417361,"score_gpt":0.23654300429569985,"score_spread":0.2227079483782825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157130670","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99515235,0.0030433799,0.000001724678,0.00019594812,0.000073006035,0.0013044798,0.0001830147,0.000018335526,0.000027727314],"genre_scores_gemma":[0.9973959,0.002193973,0.000014327149,0.0002189135,0.000036151963,0.0000835854,0.000008826386,0.000022708056,0.000025628831],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983699,0.0002332088,0.0002614083,0.00058981293,0.0002481424,0.0002975638],"domain_scores_gemma":[0.99875516,0.00051414425,0.00018179519,0.00027820593,0.000016475755,0.00025423887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003552155,0.00035014356,0.00037305732,0.00018867469,0.00011337761,0.00006379809,0.00011012057,0.00004288523,0.000013864016],"category_scores_gemma":[0.00007311411,0.0002367723,0.00006796642,0.0002590894,0.00025117968,0.00016415076,0.00006011811,0.0001225553,0.000002159835],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002332205,0.0090947645,0.056108825,0.0011743758,0.000100755504,0.0002260923,0.0012445801,0.0000089175965,0.81617266,0.00012231153,0.00015801017,0.11325648],"study_design_scores_gemma":[0.0055225375,0.0017334933,0.93404967,0.000060293478,0.000071778806,0.000012617918,0.000047531426,0.00023645553,0.05782256,0.00021932607,0.000016695636,0.00020706553],"about_ca_topic_score_codex":0.0002657532,"about_ca_topic_score_gemma":0.00012490418,"teacher_disagreement_score":0.87794083,"about_ca_system_score_codex":0.000025647716,"about_ca_system_score_gemma":0.000060874543,"threshold_uncertainty_score":0.96552944},"labels":[],"label_agreement":null},{"id":"W2157480158","doi":"10.2174/156720511795745366","title":"The Mechanism of Memory Impairment Induced by A&amp;#946; Chronic Administration Involves Imbalance between Cytokines and Neurotrophins in the Rat Hippocampus","year":2011,"lang":"en","type":"article","venue":"Current Alzheimer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"Canadian Institutes of Health Research","keywords":"Neurotrophic factors; Glial cell line-derived neurotrophic factor; Neuroinflammation; Neurotrophin; Proinflammatory cytokine; Nerve growth factor; Alzheimer's disease; Tumor necrosis factor alpha; Cytokine; Hippocampus; Immunology; Neuroscience; Medicine; Inflammation; Endocrinology; Internal medicine; Psychology; Disease; Receptor","score_opus":0.2537441849689178,"score_gpt":0.3935261134121121,"score_spread":0.13978192844319426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157480158","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921863,0.0054515023,0.000011547127,0.00088969315,0.00023231906,0.0009986914,0.000016013295,0.00002203808,0.00019188675],"genre_scores_gemma":[0.99844134,0.0012475379,0.0000082077595,0.00003699063,0.000088480694,0.00013776777,0.000006617194,0.000017571185,0.000015517073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968991,0.0010007003,0.0003372126,0.00044975395,0.0007652782,0.00054789806],"domain_scores_gemma":[0.9985384,0.0007013978,0.00010870713,0.00049531745,0.00006358636,0.00009260574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012191061,0.0001791696,0.00017533613,0.00013853259,0.0003752315,0.00009897308,0.00082374807,0.000065362176,0.000019982275],"category_scores_gemma":[0.0003179364,0.000110085704,0.00005336724,0.00056799286,0.0005592713,0.00017762849,0.0002126355,0.0006396123,0.000018947896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038988376,0.0011116752,0.0032823882,0.0001686392,0.000061138664,0.0000139069725,0.008731316,7.436599e-7,0.8643376,0.0150564695,0.0039749993,0.10287125],"study_design_scores_gemma":[0.0018053515,0.0018108212,0.025278376,0.00012584934,0.000040079318,0.000013054631,0.0012491568,0.0001292209,0.9393896,0.025073618,0.0046422915,0.00044261798],"about_ca_topic_score_codex":0.000049336697,"about_ca_topic_score_gemma":0.00010199796,"teacher_disagreement_score":0.10242862,"about_ca_system_score_codex":0.00002927353,"about_ca_system_score_gemma":0.00018785473,"threshold_uncertainty_score":0.4489165},"labels":[],"label_agreement":null},{"id":"W2159554191","doi":"10.2147/ndt.s89922","title":"A meta-analysis of lipid peroxidation markers in major depression","year":2015,"lang":"en","type":"review","venue":"Neuropsychiatric Disease and Treatment","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Centre for Addiction and Mental Health; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research","keywords":"Lipid peroxidation; Major depressive disorder; Medicine; Antidepressant; Internal medicine; Depression (economics); Mood; Meta-analysis; Psychiatry; Oxidative stress","score_opus":0.10785791373255024,"score_gpt":0.3357906896393308,"score_spread":0.22793277590678054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159554191","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015809078,0.99630755,0.0000019459496,0.000036033354,0.00011068439,0.0009994439,0.00038036614,0.000030212159,0.00055283715],"genre_scores_gemma":[0.002964182,0.9961607,0.00002502568,0.000065716136,0.000031719173,0.00025810188,0.00009669759,0.00003619071,0.00036167837],"study_design_codex":"design_other","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9973519,0.000584891,0.0005944333,0.0008791575,0.00035388593,0.00023573558],"domain_scores_gemma":[0.9985281,0.00023694042,0.00039439945,0.0005393868,0.00001891188,0.0002822627],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000097642165,0.00047317115,0.002157019,0.0010923347,0.000051860243,0.000039886472,0.00019470649,0.00008905292,0.00014156326],"category_scores_gemma":[0.000063717824,0.0003017959,0.0017330361,0.0020148023,0.00005671544,0.00008696706,0.0000620518,0.00009740085,0.000016101718],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026244018,0.0022722157,0.00030694975,0.002282702,0.032195322,0.00014932726,0.000090775226,0.000030776366,0.0000029532584,0.00013892386,0.00027937707,0.9619882],"study_design_scores_gemma":[0.0014386277,0.00028537947,0.0012948798,0.00012652506,0.7271977,0.000005411365,0.000016488995,0.00008611108,0.0000032390712,0.00006888092,0.26893878,0.00053799676],"about_ca_topic_score_codex":0.000038301707,"about_ca_topic_score_gemma":0.000023282719,"teacher_disagreement_score":0.9614502,"about_ca_system_score_codex":0.000059764054,"about_ca_system_score_gemma":0.00021445693,"threshold_uncertainty_score":0.99994344},"labels":[],"label_agreement":null},{"id":"W2159809009","doi":"10.2217/pgs.15.136","title":"Genetic Variation in <i>IL-1β, IL-2, IL-6, TSPO</i> and <i>BDNF</i> and Response to Duloxetine or Placebo Treatment in Major Depressive Disorder","year":2015,"lang":"en","type":"article","venue":"Pharmacogenomics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Michael's Hospital; University of Toronto; University Health Network; Canada Research Chairs; Centre for Addiction and Mental Health","funders":"","keywords":"Duloxetine; Placebo; Major depressive disorder; Internal medicine; Duloxetine Hydrochloride; Rating scale; Depression (economics); Placebo response; Medicine; Psychology; Psychiatry","score_opus":0.030554426211723957,"score_gpt":0.28985612262565036,"score_spread":0.2593016964139264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159809009","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966438,0.0004018737,0.00012599617,0.0012432894,0.00015561336,0.0010867049,0.00016360168,0.000039370534,0.00013977155],"genre_scores_gemma":[0.9961233,0.0007137502,0.00064676907,0.00193259,0.000054226493,0.0001692901,0.0000034789027,0.000042313568,0.00031424226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980825,0.0003651668,0.00033632407,0.0006412976,0.00016762207,0.0004070921],"domain_scores_gemma":[0.9989426,0.00045292146,0.00008991532,0.00020230885,0.000022709914,0.00028955637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030941045,0.0002736424,0.0002634496,0.00024819764,0.000076999895,0.00007454389,0.00016922166,0.000069911745,0.000025291116],"category_scores_gemma":[0.00041944452,0.0002441734,0.00002649575,0.00039141663,0.00007813837,0.00014795961,0.00014537282,0.00012410371,0.000031682895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015454284,0.00051757175,0.009182849,0.000028131444,0.000013698505,0.00024574515,0.007909964,0.0017856562,0.95075136,0.000028947698,0.0003052393,0.013776541],"study_design_scores_gemma":[0.10448493,0.00263162,0.15660445,0.000111893045,0.00017160967,0.00038186111,0.0021807826,0.022868998,0.59733427,0.0014184803,0.10912034,0.0026907828],"about_ca_topic_score_codex":0.00024558746,"about_ca_topic_score_gemma":0.00047554975,"teacher_disagreement_score":0.3534171,"about_ca_system_score_codex":0.00018260235,"about_ca_system_score_gemma":0.0001645019,"threshold_uncertainty_score":0.99571025},"labels":[],"label_agreement":null},{"id":"W2159890531","doi":"10.7202/1014956ar","title":"Ce que la microscopie peut nous apprendre sur le suicide","year":2013,"lang":"fr","type":"article","venue":"Santé mentale au Québec","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Neuroanatomy; Context (archaeology); Neuroimaging; Mood; Mood disorders; Neuroscience; Psychology; Depression (economics); White matter; Medicine; Psychiatry; Biology; Magnetic resonance imaging; Anxiety","score_opus":0.02026879131668936,"score_gpt":0.26582554315062773,"score_spread":0.24555675183393838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159890531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95114636,0.0070348727,0.000088548426,0.00559428,0.0014930457,0.00078169804,0.00010926001,0.00015929154,0.033592653],"genre_scores_gemma":[0.9481517,0.00034725855,0.00026120638,0.002501537,0.00023857343,0.000085309184,0.000014926124,0.00008813437,0.048311364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968067,0.00035841466,0.0004714961,0.0008707112,0.00038749017,0.0011051896],"domain_scores_gemma":[0.998266,0.0005384124,0.00018737798,0.0006336167,0.000043752203,0.00033088337],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00017875906,0.0004792957,0.00040618566,0.00011533362,0.0005546989,0.0002576379,0.0007242851,0.00023761445,0.0030688015],"category_scores_gemma":[0.00019994318,0.0005112856,0.00023388742,0.00035841845,0.0011374672,0.0006934309,0.00029949876,0.00043226095,0.004340164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049579587,0.0018803462,0.010367763,0.00037873472,0.000055523076,0.00018864185,0.008755436,0.000021128424,0.82585883,0.002153027,0.040328033,0.10996294],"study_design_scores_gemma":[0.0030895215,0.00030557017,0.04152539,0.00036604443,0.000044705386,0.00035889103,0.0063554863,0.000285638,0.6891297,0.0003180409,0.25707442,0.0011466111],"about_ca_topic_score_codex":0.49186537,"about_ca_topic_score_gemma":0.15801848,"teacher_disagreement_score":0.3338469,"about_ca_system_score_codex":0.0005479171,"about_ca_system_score_gemma":0.0027058935,"threshold_uncertainty_score":0.99973387},"labels":[],"label_agreement":null},{"id":"W2161000933","doi":"10.1038/tp.2012.26","title":"Discovery of blood transcriptomic markers for depression in animal models and pilot validation in subjects with early-onset major depression","year":2012,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institutes of Health; Davee Foundation; National Institute of Mental Health; Nationwide Children's Hospital","keywords":"Depression (economics); Animal model; Schizophrenia (object-oriented programming); Transcriptome; Behavioral medicine; Psychiatry; Medicine; Animal models of depression; Psychology; Clinical psychology; Internal medicine; Biology; Genetics; Antidepressant; Anxiety; Gene","score_opus":0.02715166385665363,"score_gpt":0.2632784488099276,"score_spread":0.236126784953274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161000933","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99518603,0.0005814868,0.0029979164,0.00020824696,0.00010867437,0.00058985496,0.00008172355,0.000017982176,0.00022806418],"genre_scores_gemma":[0.9977413,0.000021259288,0.0020353254,0.00007218247,0.00002968295,0.00004768673,0.000019498646,0.000022698643,0.00001039123],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99883217,0.00008880321,0.00028293216,0.00030623272,0.00023036555,0.00025949455],"domain_scores_gemma":[0.9995887,0.00016730485,0.000076528,0.00010740257,0.000010219549,0.000049799422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017414178,0.0001503862,0.00016201827,0.00019694476,0.0000523927,0.000020275469,0.000097446886,0.000069396396,0.0000069436105],"category_scores_gemma":[0.000012596604,0.00013044591,0.000041577397,0.00023268646,0.0000729999,0.0009925803,0.0000059826625,0.00011608521,4.4280364e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0049515353,0.0006957217,0.8444191,0.00014081741,0.000007957092,4.0863642e-7,0.0006098791,0.00056337146,0.14678006,0.0016098084,0.000013834278,0.00020748714],"study_design_scores_gemma":[0.0061977035,0.00022773577,0.9359274,0.00017265645,0.00002541958,0.000009221612,0.00007180424,0.0014533766,0.050596114,0.0051170727,0.0000016968494,0.00019980718],"about_ca_topic_score_codex":0.00004352919,"about_ca_topic_score_gemma":0.00019384938,"teacher_disagreement_score":0.09618394,"about_ca_system_score_codex":0.000006341245,"about_ca_system_score_gemma":0.000060904982,"threshold_uncertainty_score":0.531943},"labels":[],"label_agreement":null},{"id":"W2161663172","doi":"10.1111/j.1542-4758.2010.00464.x","title":"Relationship between an increased serum kynurenine/tryptophan ratio and atherosclerotic parameters in hemodialysis patients","year":2010,"lang":"en","type":"article","venue":"Hemodialysis International","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Kynurenine; Quartile; Medicine; Internal medicine; Tryptophan; Endocrinology; Common carotid artery; Hemodialysis; Body mass index; Carotid arteries; Chemistry; Biochemistry; Amino acid; Confidence interval","score_opus":0.03287018631946891,"score_gpt":0.27204111793386276,"score_spread":0.23917093161439384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161663172","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99762315,0.0000027697934,0.000321451,0.0003382206,0.0003999363,0.00026841386,0.000090939764,0.00008078948,0.00087434513],"genre_scores_gemma":[0.9977721,0.00000336427,0.0012227338,0.00047609082,0.00020183208,0.00004561482,0.00014835273,0.00003170551,0.00009823441],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.997637,0.000262989,0.00049928325,0.0007074015,0.0005726318,0.00032073667],"domain_scores_gemma":[0.9983022,0.0008345143,0.00019694427,0.00038596345,0.000076665536,0.00020366648],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033730344,0.00025719192,0.00029731952,0.00055343437,0.00017280842,0.00020575055,0.00049474626,0.00017884467,0.00018307245],"category_scores_gemma":[0.0022564637,0.0002626665,0.00012389179,0.000556204,0.00020592603,0.0006570405,0.0001028827,0.00043223967,0.000056583736],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042061292,0.00023108612,0.97537327,0.0000049218243,0.000015686386,0.0000027747544,0.00039944006,0.000105654966,0.019071573,0.0017253945,0.00003502047,0.0029931054],"study_design_scores_gemma":[0.0019207273,0.000042305513,0.96472013,0.000007826922,0.000026010122,0.0000017225799,0.000038078233,0.0032725504,0.026515922,0.0030688706,0.0000981033,0.00028772512],"about_ca_topic_score_codex":0.000117609416,"about_ca_topic_score_gemma":0.0003326315,"teacher_disagreement_score":0.010653122,"about_ca_system_score_codex":0.00006373127,"about_ca_system_score_gemma":0.00004803597,"threshold_uncertainty_score":0.99998254},"labels":[],"label_agreement":null},{"id":"W2162870899","doi":"10.1097/01.psy.0000174172.82428.ce","title":"Clinical Depression and Regulation of the Inflammatory Response During Acute Stress","year":2005,"lang":"en","type":"article","venue":"Psychosomatic Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":254,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"","keywords":"Depression (economics); Medicine; Internal medicine; Tumor necrosis factor alpha; Stressor; Interleukin 6; Inflammation; Anxiety; Psychoneuroimmunology; Endocrinology; Immunology; Psychiatry; Immune system","score_opus":0.022761356796133583,"score_gpt":0.3237464369636259,"score_spread":0.30098508016749237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162870899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954771,0.00012001962,0.00003877676,0.0033201228,0.00021419124,0.0002363745,0.0000018115467,0.00003079724,0.00056081923],"genre_scores_gemma":[0.9987405,0.000095684,0.00012373767,0.00044429957,0.00013080775,0.0000064842743,2.8418572e-7,0.000008992744,0.00044919454],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99862295,0.00031828575,0.00042891694,0.00021736659,0.00029404584,0.000118407115],"domain_scores_gemma":[0.9988423,0.0004988124,0.00020599939,0.00037121083,0.000014556274,0.00006713823],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003718353,0.000089665766,0.00016390614,0.000057515324,0.000087786946,0.0000047686963,0.00018595673,0.00005423111,0.00009446422],"category_scores_gemma":[0.001019662,0.000052295974,0.000034678407,0.0001492573,0.00034007154,0.00008365315,0.00004961711,0.00011199397,0.0000069458583],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005057642,0.00008032242,0.13385312,0.00008898621,0.000010892497,0.0000015583945,0.0009798133,0.00001251958,0.8564947,0.00012879215,0.000625134,0.007218348],"study_design_scores_gemma":[0.0016435964,0.00004272488,0.9299606,0.00040556202,0.000011374282,0.000018772875,0.000065517095,0.0005509527,0.066577226,0.00025063043,0.00041555424,0.000057506386],"about_ca_topic_score_codex":0.0000010231263,"about_ca_topic_score_gemma":0.0000016229928,"teacher_disagreement_score":0.7961075,"about_ca_system_score_codex":0.000007062855,"about_ca_system_score_gemma":0.000014481412,"threshold_uncertainty_score":0.21325679},"labels":[],"label_agreement":null},{"id":"W2162987312","doi":"10.1002/ibd.21531","title":"Adoptive transfer of macrophage from mice with depression-like behavior enhances susceptibility to colitis","year":2011,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"Crohn's and Colitis Foundation of Canada; Canadian Association of Gastroenterology; Crohn's and Colitis Foundation; Institut de France","keywords":"Colitis; Macrophage; Adoptive cell transfer; Depression (economics); Medicine; Immunology; Inflammatory bowel disease; Biology; Internal medicine; Immune system; Disease; T cell; Genetics","score_opus":0.019217336331401328,"score_gpt":0.2378802591123029,"score_spread":0.21866292278090158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162987312","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99694526,0.00012454261,0.00017792225,0.000008627864,0.00016365404,0.00071507297,0.0008714058,0.00013456665,0.0008589706],"genre_scores_gemma":[0.999093,0.000017370607,0.00021215157,0.00031780545,0.000035929854,0.00019192963,0.000008131606,0.000032645956,0.00009105817],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99809885,0.00016204733,0.00033262893,0.0006616095,0.00039173118,0.00035315353],"domain_scores_gemma":[0.99884295,0.00017978439,0.00007400506,0.0004733167,0.000074710435,0.00035525628],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000045939723,0.0002627969,0.00025312763,0.00008485901,0.00012015303,0.00002730201,0.00044262133,0.0000741149,0.0012050351],"category_scores_gemma":[0.0001202596,0.0002183131,0.000121932644,0.00018229331,0.0004399569,0.0003104315,0.000070177804,0.000109155655,0.000078937795],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004035297,0.0015151728,0.4000659,0.00015696629,0.000035081397,0.00063295785,0.0050017475,0.000016277412,0.5838279,0.00026790725,0.00035931345,0.004085478],"study_design_scores_gemma":[0.00048778008,0.00010283604,0.62395614,0.00006010318,0.00003599941,0.0000014746223,0.00034051063,0.0000026926787,0.374638,0.00009147117,0.00008356203,0.00019947489],"about_ca_topic_score_codex":0.00020985576,"about_ca_topic_score_gemma":0.00048304323,"teacher_disagreement_score":0.22389023,"about_ca_system_score_codex":0.000027871296,"about_ca_system_score_gemma":0.00011842517,"threshold_uncertainty_score":0.999708},"labels":[],"label_agreement":null},{"id":"W2163286994","doi":"10.1053/j.gastro.2010.06.063","title":"Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice","year":2010,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":672,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hamilton Health Sciences; St. Joseph's Hospital; McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Kynurenine; Inflammation; Immunology; Tumor necrosis factor alpha; Endocrinology; Internal medicine; Kynurenine pathway; Biology; Medicine; Tryptophan; Biochemistry","score_opus":0.00828324180399622,"score_gpt":0.22168906598139548,"score_spread":0.21340582417739926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163286994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988064,0.000009814144,0.00007443593,0.0003613069,0.00036531352,0.0002159935,0.0000117942145,0.00007833589,0.000076573844],"genre_scores_gemma":[0.99925727,0.0000049270375,0.00030817935,0.00017184597,0.00017286635,0.000043541942,0.000008293197,0.000015360123,0.000017743767],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984915,0.00008515973,0.00026162318,0.00045105844,0.000116251744,0.00059438834],"domain_scores_gemma":[0.99953246,0.000034364617,0.0001165048,0.00017460562,0.00001446949,0.00012762228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008992558,0.00017941563,0.00016953549,0.00010047475,0.00006558047,0.00003993481,0.00022860392,0.00007969863,0.000023343648],"category_scores_gemma":[0.000070216985,0.00018365444,0.000039285143,0.00009180167,0.00025339305,0.0001267452,0.00008977954,0.00041158736,0.000010546858],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007169425,0.00003204813,0.099029146,0.00004359113,0.0000010829673,0.000047052064,0.000063916,0.000011509792,0.89864445,0.00003879952,0.000026210599,0.0019904838],"study_design_scores_gemma":[0.0024362728,0.00054682605,0.6135529,0.00007996706,0.000014839577,0.004381973,0.00030770476,0.0007339928,0.37760934,0.000012918867,0.000113391034,0.00020985158],"about_ca_topic_score_codex":0.00004071547,"about_ca_topic_score_gemma":0.00036223923,"teacher_disagreement_score":0.52103513,"about_ca_system_score_codex":0.00007034715,"about_ca_system_score_gemma":0.000040552703,"threshold_uncertainty_score":0.7489211},"labels":[],"label_agreement":null},{"id":"W2163828684","doi":"10.4049/jimmunol.173.10.5909","title":"Cutting Edge: Human Eosinophils Regulate T Cell Subset Selection through Indoleamine 2,3-Dioxygenase","year":2004,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":205,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"Indoleamine 2,3-dioxygenase; CD28; Immunology; Allergic inflammation; Eosinophilia; Interferon gamma; Biology; Interleukin 5; T cell; Jurkat cells; Molecular biology; Cytokine; Allergy; Interleukin; Immune system; Tryptophan; Biochemistry","score_opus":0.023103610321120873,"score_gpt":0.26258018111284487,"score_spread":0.239476570791724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163828684","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960179,0.00072585576,0.00043632786,0.0012304226,0.0003535016,0.000105211155,0.0000018360856,0.000031378713,0.0010976121],"genre_scores_gemma":[0.99830204,0.00031439745,0.00017223772,0.00076268875,0.00016764291,9.285228e-7,4.5062825e-7,0.000020801053,0.0002587869],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985733,0.00031299866,0.00044732483,0.00013989728,0.00019078064,0.00033567596],"domain_scores_gemma":[0.9989957,0.00014874413,0.00052886625,0.00021435985,0.000079337624,0.00003297332],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003718374,0.00015486695,0.0002313582,0.00012126822,0.00036847751,0.0000283743,0.0005157023,0.000101409256,0.00007085004],"category_scores_gemma":[0.00019436255,0.0001069044,0.00010192452,0.00036541722,0.00027458006,0.00027176933,0.000069542126,0.00055819436,0.000038746173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014944247,0.00013044,0.000011862901,0.000006255059,0.000015211363,0.00002181045,0.0010036294,0.00053035567,0.9964982,0.0008884417,0.0003199872,0.00042435655],"study_design_scores_gemma":[0.001802311,0.0005872868,0.0018886654,0.000029234034,0.000011583811,0.0010727042,0.0002866654,0.0000047823078,0.9842773,0.008719354,0.0012068646,0.0001132663],"about_ca_topic_score_codex":0.00003232268,"about_ca_topic_score_gemma":0.0000073614215,"teacher_disagreement_score":0.012220925,"about_ca_system_score_codex":0.00008301317,"about_ca_system_score_gemma":0.00008000318,"threshold_uncertainty_score":0.4359435},"labels":[],"label_agreement":null},{"id":"W2164171672","doi":"10.1177/070674370605100602","title":"Genetic Associations between Delusional Disorder and Paranoid Schizophrenia: A Novel Etiologic Approach","year":2006,"lang":"en","type":"article","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Paranoid schizophrenia; Schizophrenia (object-oriented programming); Delusional disorder; Psychiatry; Human leukocyte antigen; Population; Psychology; Linkage disequilibrium; Psychosis; Medicine; Allele; Genetics; Haplotype; Immunology; Gene; Biology","score_opus":0.020850845689594524,"score_gpt":0.22969371698830376,"score_spread":0.20884287129870924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164171672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9843797,0.0014114024,0.0012247021,0.010774704,0.00043097333,0.00012997555,0.00010736569,0.000009023486,0.0015321599],"genre_scores_gemma":[0.9933798,0.000009704675,0.0052151354,0.0007392326,0.00055125885,0.0000019969184,0.0000030621386,0.0000131630195,0.00008666203],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989207,0.00010546564,0.00032235478,0.0001558674,0.00020490157,0.00029075413],"domain_scores_gemma":[0.9992708,0.00012067402,0.00023577374,0.00012917661,0.00004069764,0.00020286499],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002298328,0.00012343097,0.00016882728,0.00015354497,0.0006447337,0.00009194732,0.0003505321,0.00008893115,0.000030837644],"category_scores_gemma":[0.00011392631,0.00008608302,0.00009337596,0.00027230446,0.0002558209,0.00007682296,0.000016440881,0.00033713563,0.0000065639306],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004202077,0.00019459239,0.86175907,0.000017860197,0.00005398076,0.000011012434,0.0002845486,0.0019056826,0.0014300906,0.123095304,0.009492382,0.0017134419],"study_design_scores_gemma":[0.0009064855,0.000058080313,0.9503289,0.000009863272,0.0000289175,0.00011808561,0.00007408446,0.00008231687,0.000026187643,0.047332205,0.0008971522,0.00013772424],"about_ca_topic_score_codex":0.0034881148,"about_ca_topic_score_gemma":0.092516474,"teacher_disagreement_score":0.08902836,"about_ca_system_score_codex":0.000045546185,"about_ca_system_score_gemma":0.00092195056,"threshold_uncertainty_score":0.92404276},"labels":[],"label_agreement":null},{"id":"W2165407125","doi":"10.1016/s0006-3223(01)01265-3","title":"Comment on “ketamine has equal affinity for NMDA receptors and the high-affinity state of the dopamine D2 receptor”: Reply","year":2001,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"NMDA receptor; Receptor; Dopamine receptor D2; Ketamine; Dopamine; Dopamine receptor; Neuroscience; Chemistry; Political science; Pharmacology; Psychology; Medicine; Biochemistry","score_opus":0.06001710025865619,"score_gpt":0.2714008261522204,"score_spread":0.2113837258935642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165407125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9286633,0.0001315101,0.00009272466,0.06753817,0.0018677727,0.00089989207,0.00010044404,0.000070096954,0.00063605193],"genre_scores_gemma":[0.97686994,0.0003489236,0.00042318102,0.021922719,0.00016419627,0.00005791504,0.000009209098,0.000013916404,0.00018999376],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99785453,0.00060672034,0.00042881427,0.0005250965,0.00022395715,0.0003609042],"domain_scores_gemma":[0.9975095,0.0015872521,0.00027745226,0.0005077863,0.000032594467,0.00008543819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006813358,0.00024526505,0.00033109816,0.000035644658,0.0004400914,0.00004331955,0.0005642381,0.00010131734,0.00011489009],"category_scores_gemma":[0.0015592702,0.000113064576,0.00018736039,0.00031318597,0.001222784,0.000042094034,0.00018301257,0.00029605243,0.000016046655],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03819571,0.008929969,0.07092008,0.00026157027,0.0002027974,0.000003511258,0.0013195332,0.00015446398,0.06000341,0.3686419,0.3808317,0.07053534],"study_design_scores_gemma":[0.02043093,0.0068289223,0.13259909,0.0001595938,0.000045710967,0.000016108133,0.0006984036,0.00012703,0.062435817,0.11024093,0.6651916,0.0012258571],"about_ca_topic_score_codex":0.00003711071,"about_ca_topic_score_gemma":0.00004226591,"teacher_disagreement_score":0.28435993,"about_ca_system_score_codex":0.000021043677,"about_ca_system_score_gemma":0.000040474013,"threshold_uncertainty_score":0.46106398},"labels":[],"label_agreement":null},{"id":"W2165520691","doi":"10.1016/j.jad.2015.08.058","title":"Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: Evidence, pathophysiology and treatment implications","year":2015,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":171,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Pathophysiology; Bipolar disorder; Inflammation; Cognition; Cognitive impairment; Neuroscience; Psychology; Medicine; Pathology; Internal medicine","score_opus":0.05311315197015267,"score_gpt":0.34726324423374155,"score_spread":0.2941500922635889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165520691","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15385616,0.84417886,0.00002366545,0.0001070567,0.000111143105,0.0015645701,0.0000651445,0.00001174848,0.00008168248],"genre_scores_gemma":[0.055841554,0.9439162,0.000011914873,0.000027406104,0.000041970972,0.00011084063,0.000011454399,0.000028268141,0.000010393091],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966835,0.0013600085,0.0009492033,0.00047491494,0.00021630408,0.0003161143],"domain_scores_gemma":[0.99558645,0.0025089262,0.0014261964,0.00018230315,0.00015532036,0.00014080154],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004062951,0.00046391264,0.0015531691,0.0006372926,0.00006991875,0.000028237027,0.0002762919,0.00026053799,0.000013754276],"category_scores_gemma":[0.0019186469,0.00031971087,0.000446418,0.00080980104,0.00040104598,0.00028090656,0.00007999533,0.00042972591,0.000008542082],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017430559,0.0005770268,0.00044981416,0.0005545814,0.00006726508,0.000019112404,0.00045393367,0.000014471645,0.0004989852,0.00017747597,0.000011429444,0.9970016],"study_design_scores_gemma":[0.034734733,0.11107938,0.11931517,0.0729844,0.005452252,0.0025819507,0.0084029855,0.00015434458,0.0021093378,0.071524054,0.5646212,0.0070401626],"about_ca_topic_score_codex":0.000065560285,"about_ca_topic_score_gemma":0.00015865079,"teacher_disagreement_score":0.98996145,"about_ca_system_score_codex":0.00019864897,"about_ca_system_score_gemma":0.0005684928,"threshold_uncertainty_score":0.9999255},"labels":[],"label_agreement":null},{"id":"W2165782579","doi":"10.1503/jpn.130155","title":"Oxidation and nitration in dopaminergic areas of the prefrontal cortex from patients with bipolar disorder and schizophrenia","year":2014,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Schizophrenia (object-oriented programming); Prefrontal cortex; Bipolar disorder; Dopaminergic; Neuroscience; Nitration; Psychiatry; Psychology; Medicine; Dopamine; Cognition; Chemistry","score_opus":0.0059760639704354935,"score_gpt":0.20238525745225838,"score_spread":0.1964091934818229,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165782579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988686,0.0002292373,0.00015845345,0.0003108041,0.00031358274,0.00009370841,0.0000051504344,0.0000026106584,0.000017896302],"genre_scores_gemma":[0.99944884,0.00010091161,0.00017001035,0.0002454481,0.000023887915,5.731253e-7,2.1587135e-7,0.0000045183597,0.0000055787355],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991345,0.000108177795,0.00022198158,0.00019498492,0.00024330939,0.00009705016],"domain_scores_gemma":[0.9994811,0.00006990064,0.00027998653,0.00009150662,0.000022085402,0.000055435987],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000114924784,0.00008894563,0.00011661057,0.00007928669,0.000110308625,0.00004385107,0.00013529831,0.000027109978,0.0000015811269],"category_scores_gemma":[0.00016428543,0.000054102547,0.00001734635,0.00023093075,0.00028753275,0.00039309033,0.00003567916,0.00013750678,7.366864e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018237856,0.00014096894,0.81177425,0.000011669306,6.459061e-7,3.4839243e-7,0.00008408785,0.000018353678,0.18497239,0.0005492524,0.0000047606914,0.002260886],"study_design_scores_gemma":[0.0013555271,0.00034287994,0.9922681,0.00005179691,0.0000062739095,0.000014196602,0.000031494084,0.00047478362,0.004339652,0.0009803196,0.00006918708,0.00006580007],"about_ca_topic_score_codex":0.000016401615,"about_ca_topic_score_gemma":0.00014864029,"teacher_disagreement_score":0.18063274,"about_ca_system_score_codex":0.0000031991544,"about_ca_system_score_gemma":0.000034585133,"threshold_uncertainty_score":0.22062379},"labels":[],"label_agreement":null},{"id":"W2166043067","doi":"10.1016/j.schres.2013.10.011","title":"Antipsychotics' effects on blood levels of cytokines in schizophrenia: A meta-analysis","year":2013,"lang":"en","type":"review","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":221,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institut Universitaire en Santé Mentale de Québec","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Schizophrenia (object-oriented programming); Antipsychotic; Cytokine; Medicine; Meta-analysis; Psychosis; Plasma levels; Interleukin; Interleukin 6; Internal medicine; Pharmacology; Psychiatry; Immunology","score_opus":0.2924898188616775,"score_gpt":0.4333174860860075,"score_spread":0.14082766722433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166043067","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0029420606,0.99159455,0.000007559424,0.0001470662,0.00020712079,0.003459099,0.00040688214,0.00009590264,0.0011397812],"genre_scores_gemma":[0.017097915,0.9797943,0.0005451824,0.00006273223,0.00020004713,0.0009771918,0.000025831998,0.00018582061,0.0011109482],"study_design_codex":"design_other","study_design_gemma":"meta_analysis","domain_scores_codex":[0.98653746,0.0051627127,0.0016913641,0.0023415384,0.0027151061,0.0015518453],"domain_scores_gemma":[0.988451,0.007863054,0.00060761167,0.0024568764,0.00024711716,0.00037435297],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00243505,0.0011187152,0.0067750127,0.006843951,0.00025326505,0.00027873734,0.0027898215,0.00078458653,0.0011605555],"category_scores_gemma":[0.0034327803,0.00079321564,0.004419836,0.01276069,0.0006877688,0.00023757637,0.00057921204,0.003054382,0.0010893202],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011555693,0.0021417728,0.0000037269836,0.02617246,0.055560425,0.0005575959,0.00015392374,0.000024542687,0.0025000344,0.012917936,0.0010506456,0.89776134],"study_design_scores_gemma":[0.026635807,0.006190673,0.0008630974,0.017036524,0.5274904,0.00024992716,0.00012784805,0.00018666929,0.066178545,0.026461922,0.31765667,0.010921959],"about_ca_topic_score_codex":0.00007550561,"about_ca_topic_score_gemma":0.00010763702,"teacher_disagreement_score":0.8868394,"about_ca_system_score_codex":0.00009480677,"about_ca_system_score_gemma":0.0006849288,"threshold_uncertainty_score":0.9997525},"labels":[],"label_agreement":null},{"id":"W2167020344","doi":"10.1017/s1461145706006663","title":"Cholesterol content in brains of suicide completers","year":2006,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Content (measure theory); Psychology; Cholesterol; Neuroscience; Clinical psychology; Medicine; Psychiatry; Internal medicine; Mathematics","score_opus":0.06833845921718236,"score_gpt":0.3300308531928637,"score_spread":0.26169239397568134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167020344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98682266,0.000040131566,0.0000637813,0.009531619,0.0018374803,0.000104165694,0.000009577915,0.000006585217,0.0015840078],"genre_scores_gemma":[0.9903114,0.00006701679,0.000024554965,0.009250989,0.00021017343,0.0000020341606,4.1671984e-7,0.000011177105,0.00012226733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998491,0.0002392177,0.0005910896,0.00013022702,0.00038706735,0.00016140641],"domain_scores_gemma":[0.99877906,0.00050762866,0.0004703498,0.00008777704,0.00012129141,0.000033914475],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022687968,0.00010015078,0.0001804597,0.00024390302,0.000022976945,0.000020255764,0.0010008062,0.00002609701,0.00013664192],"category_scores_gemma":[0.00014579046,0.00007161317,0.000117418196,0.00013945943,0.00022186902,0.000093661154,0.00006353367,0.00028007617,0.000011228369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047740297,0.00026352843,0.0021464743,0.0000019587405,0.000014007167,0.00013190156,0.00008539009,0.0007411843,0.9914253,0.0008175883,0.0026942024,0.0012011058],"study_design_scores_gemma":[0.011358169,0.00054367515,0.4775616,0.00006174456,0.000021146217,0.0015058595,0.00014094087,0.00052844564,0.49116457,0.0024346968,0.014463402,0.00021577698],"about_ca_topic_score_codex":0.00006155478,"about_ca_topic_score_gemma":0.00002834763,"teacher_disagreement_score":0.5002607,"about_ca_system_score_codex":0.000035923393,"about_ca_system_score_gemma":0.000035622234,"threshold_uncertainty_score":0.29203004},"labels":[],"label_agreement":null},{"id":"W2167237836","doi":"10.1007/s11010-007-9635-y","title":"Differential immunosuppressive effect of indoleamine 2,3-dioxygenase (IDO) on primary human CD4+ and CD8+ T cells","year":2007,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Jurkat cells; CD8; Cytotoxic T cell; Bystander effect; Immune system; Biology; Cell biology; T cell; Molecular biology; Immunology; Chemistry; Cancer research; Tryptophan; In vitro; Biochemistry","score_opus":0.0040285700073719646,"score_gpt":0.21260710321713444,"score_spread":0.20857853320976247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167237836","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996455,0.0005772888,0.00031466645,0.000013700117,0.000054056476,0.00019888842,0.00002099707,0.000030684037,0.0023347135],"genre_scores_gemma":[0.9995291,0.0000121388475,0.00001717597,0.00015533959,0.00003760395,0.0000052488053,0.000032602235,0.000027116368,0.00018364369],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985598,0.000076530174,0.00023892349,0.000503281,0.00027084126,0.00035063413],"domain_scores_gemma":[0.9992673,0.000113776085,0.000111012785,0.00033671237,0.000015145764,0.00015607334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012480697,0.0002701132,0.00027480352,0.000065763445,0.0001101015,0.00003444407,0.00018568622,0.00016474185,0.000034476685],"category_scores_gemma":[0.000063584266,0.0002407418,0.000104768995,0.00011274672,0.0002947256,0.000026176587,0.00014015156,0.0002091996,0.0000027511335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018750638,0.00011434771,0.000039776627,0.00027102433,0.000014546702,0.00016073044,0.00003388166,6.8161364e-7,0.9981097,0.00006927117,0.00003860711,0.00095995277],"study_design_scores_gemma":[0.0015294255,0.00029254198,0.00019044339,0.00005505172,0.000013956936,0.000014900591,0.000025210518,0.000004935858,0.9975548,0.00004348074,0.00003565682,0.00023963157],"about_ca_topic_score_codex":0.0000056483254,"about_ca_topic_score_gemma":1.4340128e-7,"teacher_disagreement_score":0.0030741254,"about_ca_system_score_codex":0.00001693809,"about_ca_system_score_gemma":0.00001255946,"threshold_uncertainty_score":0.98171663},"labels":[],"label_agreement":null},{"id":"W2167275173","doi":"10.1139/y2012-080","title":"A study about drug combination therapy of<i>Schisandra sphenanthera</i>extract and Rapamycin in healthy subjects","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Bioavailability; Pharmacology; Pharmacokinetics; Oral administration; Drug; Medicine; Schisandra","score_opus":0.027038387005464043,"score_gpt":0.3053274090205962,"score_spread":0.27828902201513217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167275173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947571,0.0037051383,9.493112e-7,0.0005534285,0.00066846213,0.00022194414,0.000005064415,0.000002324602,0.00008555949],"genre_scores_gemma":[0.9971112,0.00090979715,0.0000071016193,0.0018601363,0.00008796613,0.0000042739275,3.904494e-7,0.000007875526,0.0000112776615],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986455,0.0005656284,0.00027941362,0.00013062712,0.000051320978,0.00032753072],"domain_scores_gemma":[0.9991173,0.00031722104,0.00020612897,0.000050206294,0.000029170393,0.00027996313],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038383465,0.00010905476,0.00028334188,0.0002540913,0.00010560131,0.0000056321046,0.000118800934,0.00006009592,0.00021063132],"category_scores_gemma":[0.000041941752,0.00009114763,0.000030442166,0.00015746466,0.00030420354,0.00018123536,0.000009104453,0.00028228312,0.0000012247821],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00081029086,0.0004952602,0.06338979,0.000033639117,0.000027692411,0.000041771505,0.009649203,0.000008956089,0.9208981,0.0004673591,0.00048818707,0.0036897603],"study_design_scores_gemma":[0.010377616,0.0020744428,0.7136037,0.000016651582,0.000018268083,0.00017183219,0.0014006866,0.000019722062,0.26785958,0.0016187095,0.002609859,0.00022896714],"about_ca_topic_score_codex":0.00045640414,"about_ca_topic_score_gemma":0.0012420843,"teacher_disagreement_score":0.6530385,"about_ca_system_score_codex":0.00002214381,"about_ca_system_score_gemma":0.0002447782,"threshold_uncertainty_score":0.37168926},"labels":[],"label_agreement":null},{"id":"W2170857085","doi":"10.1016/s0165-0327(99)00100-7","title":"Lymphocyte proliferation among major depressive and dysthymic patients with typical or atypical features","year":2000,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa; Carleton University","funders":"","keywords":"Immune system; Antidepressant; Dysthymic Disorder; Major depressive disorder; Lymphocyte; Immunology; Medicine; Depression (economics); Psychology; Internal medicine; Psychiatry; Anxiety","score_opus":0.004679168258748982,"score_gpt":0.22164754683803767,"score_spread":0.2169683785792887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170857085","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99862057,0.000116361785,0.00013691932,0.00017037292,0.00007980709,0.0004009704,0.00000582689,0.00001917526,0.00044997514],"genre_scores_gemma":[0.9992172,0.00012413225,0.000088978384,0.00033123486,0.000053863267,0.000009834561,0.0000013662232,0.000022357997,0.00015102923],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998718,0.00019599455,0.00021710835,0.00026653334,0.00036124192,0.00024109636],"domain_scores_gemma":[0.99923116,0.00026130542,0.00018863547,0.00010368852,0.000077199424,0.00013803576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007077672,0.0001925033,0.00024043738,0.00011941304,0.00017813369,0.00008101345,0.00015311979,0.000091812915,0.00015852413],"category_scores_gemma":[0.0003864348,0.000119378645,0.00006816858,0.00025560037,0.00028851078,0.00047467122,0.000020118392,0.00025861317,0.0000072314333],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06145245,0.0020531092,0.55611336,0.000093072755,0.00019902117,0.00012875267,0.0026108583,0.0006948533,0.004151219,0.00044126547,0.002251568,0.3698105],"study_design_scores_gemma":[0.006469892,0.001326941,0.98586166,0.00006430026,0.00003133688,0.000057546848,0.00011389131,0.00007251958,0.005107309,0.00042580665,0.000267803,0.00020099952],"about_ca_topic_score_codex":0.0000077647865,"about_ca_topic_score_gemma":0.00017895117,"teacher_disagreement_score":0.4297483,"about_ca_system_score_codex":0.000058380305,"about_ca_system_score_gemma":0.00008782496,"threshold_uncertainty_score":0.486812},"labels":[],"label_agreement":null},{"id":"W2172799097","doi":"10.1371/journal.pone.0143435","title":"IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Pemetrexed; Cancer research; Gemcitabine; Small hairpin RNA; Immune system; Cancer; Thymidylate synthase; Gene knockdown; Medicine; Biology; Pharmacology; Chemotherapy; Immunology; Internal medicine; Cell culture","score_opus":0.12497439158007205,"score_gpt":0.2994758239437907,"score_spread":0.17450143236371862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2172799097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99745125,0.00006561636,0.000037465423,0.00092124863,0.000042111722,0.0003174894,0.00001715053,0.000054439366,0.0010932451],"genre_scores_gemma":[0.99797755,0.000015684527,0.0008859728,0.0005667113,0.000068519585,0.000024886653,0.0000021763788,0.00001550435,0.00044299744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874437,0.0001756144,0.00015504005,0.0003695124,0.00032554858,0.0002298915],"domain_scores_gemma":[0.9994441,0.00014398682,0.000051310213,0.00016787469,0.00004494286,0.00014778585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029855364,0.00012579259,0.000205123,0.00019466311,0.000056572506,0.00004358465,0.00007805136,0.000056605877,0.000029872783],"category_scores_gemma":[0.00044624554,0.00012288468,0.000015894633,0.00047664563,0.0000623527,0.00019281391,0.00008301419,0.00011574917,0.000022562888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025386222,0.0003504723,0.0013190384,0.00002301407,0.0000055199116,0.000007509717,0.00059930846,0.000055331504,0.9962261,0.00025793267,0.00010532412,0.001025095],"study_design_scores_gemma":[0.00064872694,0.00007805748,0.047038794,0.0000510035,0.000011166716,7.6351387e-7,0.00009530855,0.00048501536,0.9510264,0.00033077196,0.00006549481,0.00016853731],"about_ca_topic_score_codex":0.000347105,"about_ca_topic_score_gemma":0.0007958488,"teacher_disagreement_score":0.045719754,"about_ca_system_score_codex":0.000052790034,"about_ca_system_score_gemma":0.000028725333,"threshold_uncertainty_score":0.5011092},"labels":[],"label_agreement":null},{"id":"W2178695456","doi":"10.1155/2015/105828","title":"Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer’s Disease","year":2015,"lang":"en","type":"review","venue":"Mediators of Inflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":490,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Health and Medical Research Council; Medical Research Council; Alzheimer Society; Canadian Institutes of Health Research; Fundação de Amparo à Pesquisa do Estado de São Paulo; Curtin University of Technology; Alzheimer's Disease Research Foundation","keywords":"Insulin resistance; Oxidative stress; Inflammation; Disease; Obesity; Medicine; Alzheimer's disease; Bioinformatics; Internal medicine; Biology","score_opus":0.0373030433630299,"score_gpt":0.2989034432936384,"score_spread":0.26160039993060846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2178695456","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.110655874,0.8868517,0.000053228745,0.00019498679,0.00010364989,0.0015645669,0.00024575883,0.000055453063,0.0002747727],"genre_scores_gemma":[0.046498165,0.9529065,0.000041728923,0.00001359206,0.00021794315,0.00012354589,0.00014098745,0.000040133706,0.000017407765],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99737227,0.0007610897,0.00062958745,0.00047276434,0.0005574085,0.00020688232],"domain_scores_gemma":[0.99744743,0.000991661,0.0008779819,0.0003841334,0.0001068358,0.0001919812],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00061078905,0.00036062778,0.0007919114,0.00022925691,0.00013477929,0.00008292028,0.00029523828,0.00020073485,0.000005422489],"category_scores_gemma":[0.002334031,0.00026181756,0.00010931952,0.00041169047,0.00040645877,0.00037546593,0.00019402271,0.0002846255,0.000009310056],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000384135,0.000034734778,0.00045393984,0.0057458268,0.00009750461,0.000013004011,0.0008783226,0.0000038360463,0.00024055796,0.0066887964,0.00009715941,0.9857079],"study_design_scores_gemma":[0.0031305985,0.00023369807,0.009280796,0.0125436075,0.003773067,0.000008064269,0.00052116223,0.00012589093,0.03979759,0.02428557,0.9037138,0.0025861638],"about_ca_topic_score_codex":0.000007028919,"about_ca_topic_score_gemma":0.00002492827,"teacher_disagreement_score":0.98312175,"about_ca_system_score_codex":0.000045002307,"about_ca_system_score_gemma":0.00024423233,"threshold_uncertainty_score":0.99998343},"labels":[],"label_agreement":null},{"id":"W2179794578","doi":"10.1002/ajhb.22807","title":"Household‐level predictors of maternal mental health and systemic inflammation among infants in Mwanza, Tanzania","year":2015,"lang":"en","type":"article","venue":"American Journal of Human Biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute for Medical Research; Health Research Board","keywords":"Tanzania; Mental health; Mediation; Depression (economics); Medicine; Anxiety; Edinburgh Postnatal Depression Scale; Environmental health; Depressive symptoms; Psychiatry; Socioeconomics","score_opus":0.03579328294989925,"score_gpt":0.28442015598514914,"score_spread":0.24862687303524988,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2179794578","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9993215,0.00013588171,0.000024521642,0.00013749211,0.00018553625,0.00010463464,0.000023198572,0.000008338299,0.000058883965],"genre_scores_gemma":[0.9996136,0.00009564103,0.000057797824,0.00015166086,0.000059505808,0.0000011618338,0.0000016822447,0.000009573817,0.000009375901],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986293,0.00031174257,0.00058024103,0.00013643454,0.00014587416,0.00019641632],"domain_scores_gemma":[0.99875516,0.000047701054,0.00092174264,0.00008524833,0.000031186824,0.00015899],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034763882,0.00010187803,0.0003573912,0.00026780195,0.000038424692,0.000011149392,0.00019224586,0.000032119715,0.000004723771],"category_scores_gemma":[0.00011837163,0.000082578386,0.000033305645,0.00016015531,0.0005948996,0.00013847972,0.00004580401,0.000145102,8.247457e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016960817,0.000039877257,0.84662086,0.00001950957,0.000011720306,0.00001068296,0.0031913891,0.000014269821,0.14478683,0.00025037117,0.00016849718,0.0047163856],"study_design_scores_gemma":[0.0032310747,0.0053072963,0.9627517,0.00028329372,0.000005627941,0.0006706536,0.0048225634,0.000039341852,0.021914465,0.00058298814,0.00017379501,0.0002172339],"about_ca_topic_score_codex":0.00022353855,"about_ca_topic_score_gemma":0.0000617066,"teacher_disagreement_score":0.12287236,"about_ca_system_score_codex":0.000063053696,"about_ca_system_score_gemma":0.0001116078,"threshold_uncertainty_score":0.33674487},"labels":[],"label_agreement":null},{"id":"W2180062270","doi":"10.1016/j.euroneuro.2015.10.009","title":"Transcriptomics and the mechanisms of antidepressant efficacy","year":2015,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Dalhousie University","funders":"University of California, Los Angeles; Medical Research Council; National Institute for Health and Care Research","keywords":"Nortriptyline; Transcriptome; Escitalopram; Antidepressant; DNA microarray; Gene expression; Gene; Microarray; Biology; Gene expression profiling; Pharmacology; Bioinformatics; Genetics; Endocrinology; Amitriptyline","score_opus":0.03762706006752384,"score_gpt":0.2874673155507855,"score_spread":0.24984025548326164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2180062270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96771675,0.00019683242,0.0009326077,0.0020234403,0.0014277492,0.0004713749,0.0000089997,0.00020378885,0.02701846],"genre_scores_gemma":[0.9923513,0.00023325616,0.0001004127,0.0070048855,0.00007492365,0.0000044130884,4.1290198e-7,0.00006342524,0.0001669669],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99714553,0.001644815,0.0003205935,0.00041961527,0.00019774667,0.00027167427],"domain_scores_gemma":[0.9989691,0.00042845687,0.00013843793,0.00027812333,0.00003256566,0.00015336461],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005384004,0.0001766716,0.00024021199,0.00008144656,0.000070868125,0.000027336131,0.0005253981,0.000025612459,0.00003467072],"category_scores_gemma":[0.00039490126,0.00012223083,0.00008140504,0.00024634108,0.0007992478,0.0000776151,0.000119624005,0.00025223233,0.00006212465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012875841,0.00014560291,0.000012928433,0.000009356719,0.000009740772,0.00009842643,0.0007935949,0.000056207275,0.97245747,0.018222075,0.0038147334,0.0030922985],"study_design_scores_gemma":[0.1555562,0.0022394406,0.047450203,0.000057162462,0.00030208396,0.0013119915,0.00083822256,0.0043124887,0.6109077,0.0270521,0.1481859,0.0017865199],"about_ca_topic_score_codex":0.0000027013,"about_ca_topic_score_gemma":2.9745573e-7,"teacher_disagreement_score":0.36154976,"about_ca_system_score_codex":0.000004525391,"about_ca_system_score_gemma":0.000021423657,"threshold_uncertainty_score":0.49844286},"labels":[],"label_agreement":null},{"id":"W2183967069","doi":"10.4172/2161-0460.s2-0011","title":"Generation of Reactive Oxygen Species (ROS) and Pro-Inflammatory Signaling in Human Brain Cells in Primary Culture.","year":2012,"lang":"en","type":"article","venue":"PubMed","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Surrey Place Centre; Norgen Biotek Corporation (Canada)","funders":"National Institute on Aging","keywords":"Reactive oxygen species; Oxidative stress; Dichlorofluorescein; Neurotoxicity; Cell biology; Phospholipase A2; Neuroinflammation; Chemistry; Biology; Pharmacology; Biochemistry; Inflammation; Immunology; Enzyme; Toxicity","score_opus":0.05442687756630904,"score_gpt":0.23979725949944802,"score_spread":0.18537038193313898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2183967069","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955705,0.00012767864,0.000006607723,0.00010308072,0.00007742394,0.0006021206,0.0000045673314,0.00001644975,0.0034915656],"genre_scores_gemma":[0.99888563,0.000016563867,0.000042787266,0.00029676786,0.000088734145,0.0001883967,0.0000039160514,0.0000096632575,0.00046753552],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904627,0.000117796284,0.0002061672,0.00019650144,0.00014807777,0.00028517345],"domain_scores_gemma":[0.9996851,0.000069400485,0.000086945154,0.000093666786,0.000009378338,0.000055494518],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035269296,0.00009325816,0.00013124265,0.00012441255,0.00004004124,0.000020652235,0.00008538645,0.000057474455,0.000005947382],"category_scores_gemma":[0.00015137324,0.00008677901,0.000021249958,0.00017201364,0.00008943159,0.0003198317,0.000041623753,0.000108798304,0.0000011896328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001331599,0.000084251165,0.007999504,0.000029517323,0.0000011677728,0.000001982366,0.0019332182,0.000011008927,0.987498,0.0006508241,0.00022101529,0.0015562312],"study_design_scores_gemma":[0.0003225373,0.000005884503,0.39548773,0.0000052301075,8.734908e-7,7.4585523e-7,0.00012059809,0.000007967631,0.60335934,0.00009963023,0.00051581475,0.00007365789],"about_ca_topic_score_codex":0.000009180954,"about_ca_topic_score_gemma":0.0000310867,"teacher_disagreement_score":0.38748825,"about_ca_system_score_codex":0.00006295145,"about_ca_system_score_gemma":0.0000118062435,"threshold_uncertainty_score":0.3538745},"labels":[],"label_agreement":null},{"id":"W2185131159","doi":"10.1016/j.biopsych.2015.11.022","title":"Hippocampal Neuroinflammation, Functional Connectivity, and Depressive Symptoms in Multiple Sclerosis","year":2015,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":147,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; Canada Research Chairs; University College London; Imperial College London; Parkinson's UK; IXICO; Multiple Sclerosis Society; Association France Parkinson; Wellcome Trust; National Institute for Health and Care Research; Teva Pharmaceutical Industries; Medical Research Council; Gedeon Richter; Australian Nuclear Science and Technology Organisation; Biogen; GlaxoSmithKline; Michael J. Fox Foundation for Parkinson's Research","keywords":"Neuroinflammation; Hippocampal formation; Neuroscience; Functional connectivity; Multiple sclerosis; Hippocampal sclerosis; Depressive symptoms; Psychology; Medicine; Psychiatry; Cognition; Internal medicine; Inflammation; Temporal lobe","score_opus":0.1124899121399666,"score_gpt":0.258499272238313,"score_spread":0.14600936009834636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2185131159","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968633,0.0002280502,0.00014642718,0.0010075137,0.0006997132,0.0002008782,0.000010468481,0.00009684893,0.00074676744],"genre_scores_gemma":[0.9986682,0.00002819863,0.00009692181,0.0010192763,0.00013197892,0.000023686787,0.000004462291,0.0000074458935,0.000019809253],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987992,0.00019418237,0.00018407257,0.00044932865,0.00014280087,0.00023041348],"domain_scores_gemma":[0.99934465,0.00030255032,0.00006516599,0.0001306061,0.00001982818,0.00013720193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012106558,0.00013730292,0.0001411905,0.00006909113,0.000088315726,0.000038516515,0.00012570282,0.000119061486,0.000040293537],"category_scores_gemma":[0.0011127723,0.00010501552,0.00004016481,0.00021226119,0.00021167922,0.00012491162,0.00009115076,0.00015965679,0.000047592413],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002386061,0.00026020163,0.94371957,0.0000064968103,0.0000033052231,0.000003825509,0.0000663488,0.00012251134,0.044529848,0.0060578072,0.0017920142,0.003199457],"study_design_scores_gemma":[0.0019960843,0.0001864467,0.98213506,0.000012835311,0.000001603291,0.000016078113,0.00006760653,0.0005118901,0.0015622184,0.013023289,0.00030834996,0.00017851732],"about_ca_topic_score_codex":0.00001031188,"about_ca_topic_score_gemma":0.00004163928,"teacher_disagreement_score":0.04296763,"about_ca_system_score_codex":0.00001743533,"about_ca_system_score_gemma":0.000046433914,"threshold_uncertainty_score":0.42824087},"labels":[],"label_agreement":null},{"id":"W2187048307","doi":"10.1016/j.jpsychires.2015.10.015","title":"Nod-like receptor pyrin containing 3 (NLRP3) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation","year":2015,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":129,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Ontario Mental Health Foundation; Brain Research Foundation; Brain and Behavior Research Foundation","keywords":"Pyrin domain; Mediator; Bipolar disorder; Frontal cortex; Mitochondrion; Neuroscience; Receptor; Immune system; Nod; Psychology; Medicine; Biology; Internal medicine; Inflammasome; Immunology; Endocrinology; Cell biology; Diabetes mellitus","score_opus":0.031849797810380095,"score_gpt":0.3014372805774175,"score_spread":0.26958748276703737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2187048307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99606115,0.0009098773,0.00014518946,0.0016684316,0.000565937,0.0005045296,0.000040429608,0.000009066583,0.00009539698],"genre_scores_gemma":[0.9987815,0.000087046334,0.0004990041,0.00012253708,0.00043992727,0.000008879445,0.000015458392,0.000027428383,0.000018245768],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99587184,0.00091413053,0.000613168,0.0003304773,0.0018228171,0.0004475376],"domain_scores_gemma":[0.99810237,0.0006588494,0.00039911826,0.00025464635,0.00035406434,0.00023098265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012867477,0.000181965,0.00031883814,0.00059754704,0.00022972634,0.00019098965,0.00065354793,0.00011327252,0.000040819894],"category_scores_gemma":[0.00086701795,0.00011636009,0.000082778024,0.000924307,0.00019678813,0.00048471312,0.00009657747,0.0010359936,0.00001555762],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040253648,0.0007967,0.95649844,0.000023534518,0.000059471855,0.000037935126,0.005122952,0.000011838676,0.019505296,0.000078932586,0.0031359438,0.010703581],"study_design_scores_gemma":[0.00782514,0.0026782234,0.9791927,0.000051983894,0.000020451127,0.00001127266,0.0059873085,0.00006263359,0.0006016113,0.00061821804,0.002736054,0.00021443283],"about_ca_topic_score_codex":0.0005863349,"about_ca_topic_score_gemma":0.000101675345,"teacher_disagreement_score":0.02269422,"about_ca_system_score_codex":0.000102551705,"about_ca_system_score_gemma":0.00038731645,"threshold_uncertainty_score":0.47450268},"labels":[],"label_agreement":null},{"id":"W2190448116","doi":"10.1186/s12974-015-0454-x","title":"Electroconvulsive seizures (ECS) do not prevent LPS-induced behavioral alterations and microglial activation","year":2015,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministerie van Economische Zaken; Newfoundland and Labrador; ZonMw","keywords":"Microglia; Hippocampal formation; Open field; Dentate gyrus; Lipopolysaccharide; Hippocampus; Internal medicine; Endocrinology; Electroconvulsive therapy; Neuroinflammation; Medicine; Psychology; Neuroscience; Pharmacology; Inflammation","score_opus":0.05354296644803918,"score_gpt":0.3055136985115626,"score_spread":0.25197073206352344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2190448116","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99752086,0.000012831031,0.00022622375,0.001566393,0.0002662823,0.00022645894,0.000002680377,0.000019419045,0.00015882473],"genre_scores_gemma":[0.9993386,0.000018050392,0.00016380577,0.00013831024,0.00025930972,0.000004126728,0.000001323178,0.000013610954,0.00006284717],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987174,0.00018171484,0.00041080627,0.00016475662,0.00037050917,0.00015480617],"domain_scores_gemma":[0.9990313,0.000102829435,0.00047439145,0.00010198722,0.00016466514,0.00012481803],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001951722,0.00012170432,0.00014693277,0.00018855678,0.00010542855,0.00016040388,0.0001244911,0.000053504067,0.000009684698],"category_scores_gemma":[0.00051744794,0.00010956517,0.00006042917,0.00014850989,0.0000341244,0.0008460443,0.000026597603,0.00022523753,0.000007897326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014092418,0.00008680398,0.000028490153,0.000005624567,0.0000027676374,0.000028138391,0.00083509093,0.00008865509,0.99366874,0.00028291353,0.00027968895,0.0045521506],"study_design_scores_gemma":[0.001020839,0.0006226766,0.0018450721,0.00002041186,0.000013981184,0.00040411841,0.00012730886,0.00029754828,0.9941264,0.0008314605,0.0005841964,0.000105998806],"about_ca_topic_score_codex":0.000003571249,"about_ca_topic_score_gemma":0.0000035205614,"teacher_disagreement_score":0.0044461517,"about_ca_system_score_codex":0.00005505007,"about_ca_system_score_gemma":0.00013496983,"threshold_uncertainty_score":0.4467938},"labels":[],"label_agreement":null},{"id":"W2192082260","doi":"10.1515/jcim-2015-0051","title":"Evaluation of the antioxidant properties of tryptophan and its metabolites in <i>in vitro</i> assay","year":2015,"lang":"en","type":"article","venue":"Journal of Complementary and Integrative Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of Manitoba","funders":"","keywords":"Tryptophan; Chemistry; Biochemistry; Antioxidant; Quinolinic acid; Essential amino acid; Amino acid; Trolox; Kynurenine; DPPH","score_opus":0.11535580346035801,"score_gpt":0.32959400311957754,"score_spread":0.21423819965921953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2192082260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912836,0.005940897,0.000014081249,0.0021142229,0.00012415973,0.00021894272,0.000006997244,7.7077476e-7,0.0002963266],"genre_scores_gemma":[0.99937755,0.00027703322,0.000041632295,0.000260123,0.000029898547,0.000002034392,3.5268835e-7,0.0000029007533,0.000008502691],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979454,0.00075202883,0.0005190852,0.00008887821,0.0006090326,0.00008552521],"domain_scores_gemma":[0.9991637,0.00013537057,0.00033439734,0.00005610755,0.00026924434,0.000041189487],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024049152,0.00009225557,0.0003304655,0.00017015872,0.000018847957,0.0000035193368,0.00012792816,0.000013904303,0.000027587888],"category_scores_gemma":[0.0014412269,0.000042415682,0.000028452105,0.00024711603,0.00025315795,0.0001905177,0.000035786496,0.0001473767,5.6807842e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023128014,0.0000936636,0.0016862412,0.000020582938,0.000011796002,0.0000013349043,0.0047032726,0.0000070721244,0.9891183,0.00069665944,0.000098451754,0.003331355],"study_design_scores_gemma":[0.0036638007,0.00045442962,0.020051876,0.00042325092,0.000040889052,0.000020992056,0.010363227,0.0012579386,0.9614097,0.0020973177,0.0001709141,0.00004568178],"about_ca_topic_score_codex":0.000059829512,"about_ca_topic_score_gemma":0.000081547594,"teacher_disagreement_score":0.027708609,"about_ca_system_score_codex":0.000026544567,"about_ca_system_score_gemma":0.0000921996,"threshold_uncertainty_score":0.17296612},"labels":[],"label_agreement":null},{"id":"W2192846808","doi":"10.4088/jcp.14m09395","title":"Inflammatory Markers Among Adolescents and Young Adults With Bipolar Spectrum Disorders","year":2015,"lang":"en","type":"article","venue":"The Journal of Clinical Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Spectrum (functional analysis); Medicine; Psychology; Clinical psychology; Physics","score_opus":0.021403135153938407,"score_gpt":0.292508997640197,"score_spread":0.27110586248625856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2192846808","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99300826,0.00077811535,0.00009596788,0.0029070596,0.0021907226,0.00018064145,0.0000018589495,0.000021433116,0.0008159234],"genre_scores_gemma":[0.99763775,0.0007374674,0.00014255036,0.000956959,0.00043627212,5.919955e-7,1.09397405e-7,0.00002502989,0.000063259286],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976202,0.00054756703,0.0008205395,0.00020158663,0.00053481007,0.00027528842],"domain_scores_gemma":[0.9983255,0.00025639424,0.0007347882,0.0002770402,0.00003563755,0.000370619],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001623924,0.0001762847,0.00031337107,0.00008293103,0.00011022234,0.00004062376,0.0004954648,0.000100509504,0.000012489327],"category_scores_gemma":[0.0006752857,0.00010082705,0.00013875232,0.00020332904,0.00068026356,0.0002883253,0.00006966288,0.00079175737,0.0000140400825],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037995027,0.00023514612,0.9898273,0.000031354877,0.000025214153,0.000007694313,0.00030790962,0.000020917763,0.000018484834,0.00014538247,0.0028667026,0.0027144402],"study_design_scores_gemma":[0.005616541,0.0011866434,0.98477936,0.00035578266,0.0000509562,0.00012075617,0.0013072513,0.00012605538,0.000039518345,0.0044075744,0.0017977343,0.00021182283],"about_ca_topic_score_codex":0.000017482997,"about_ca_topic_score_gemma":0.00034785375,"teacher_disagreement_score":0.005047886,"about_ca_system_score_codex":0.000011601977,"about_ca_system_score_gemma":0.00022198551,"threshold_uncertainty_score":0.41116077},"labels":[],"label_agreement":null},{"id":"W2200032699","doi":"10.1093/rheumatology/kev272","title":"Depressive symptoms predict future simple disease activity index scores and simple disease activity index remission in a prospective cohort of patients with early inflammatory polyarthritis","year":2015,"lang":"en","type":"article","venue":"Lara D. Veeken","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Arthritis Society; Agenția Națională pentru Cercetare și Dezvoltare","keywords":"Medicine; Prospective cohort study; Polyarthritis; Internal medicine; Disease; Index (typography); Cohort; Depression (economics); Physical therapy; Arthritis","score_opus":0.0066875853931551744,"score_gpt":0.2241836621415521,"score_spread":0.21749607674839694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2200032699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99762106,0.0001268261,0.000062660234,0.00006131679,0.0000753355,0.0014459208,0.00042158322,0.00009258259,0.00009270608],"genre_scores_gemma":[0.99961036,0.00002480485,0.000003996476,0.00007327998,0.00007543343,0.00012735862,0.000020916696,0.000041534437,0.000022340286],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974738,0.00025929708,0.00023145862,0.0007942274,0.0007906533,0.00045059805],"domain_scores_gemma":[0.9982903,0.00013039695,0.00025691924,0.0005031019,0.00010965393,0.00070960517],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012009309,0.00032909124,0.0003725208,0.00016953735,0.0001345363,0.000075340555,0.0002602753,0.0001283637,0.000014593228],"category_scores_gemma":[0.00054143585,0.00028203125,0.00006441333,0.00041796418,0.00035842558,0.000902419,0.000254279,0.000353849,0.0000018310961],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005630114,0.0005657288,0.9885748,0.000074630756,0.000018001527,0.000078382465,0.00044279342,0.0000637348,0.001115288,0.000026934262,0.000077910685,0.0033316785],"study_design_scores_gemma":[0.0044222916,0.00031632476,0.99061716,0.00010394605,0.000022617278,9.436462e-7,0.000038190767,0.00052927795,0.00271878,0.0008290352,0.00007338797,0.00032802162],"about_ca_topic_score_codex":0.00022793551,"about_ca_topic_score_gemma":0.00021434932,"teacher_disagreement_score":0.0030036569,"about_ca_system_score_codex":0.00010594877,"about_ca_system_score_gemma":0.0003259036,"threshold_uncertainty_score":0.99996316},"labels":[],"label_agreement":null},{"id":"W2201064350","doi":"10.1080/19490976.2015.1107696","title":"A dysbiotic subpopulation of alcohol-dependent subjects","year":2015,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Dysbiosis; Alcohol dependence; Intestinal permeability; Alcohol; Addiction; Biology; Psychological intervention; Psychiatry; Immunology; Microbiome; Bioinformatics; Psychology","score_opus":0.06568011584854871,"score_gpt":0.2840949044867092,"score_spread":0.2184147886381605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2201064350","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99548227,0.0001368884,0.00012174711,0.00015899117,0.0002449807,0.00014437428,0.000010104965,0.000058920385,0.0036417062],"genre_scores_gemma":[0.99877644,0.000011100143,0.00019852622,0.0002446203,0.000028458606,0.0000022427112,0.0000035617347,0.000011808481,0.0007232662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991861,0.000061042876,0.00016747932,0.00022328807,0.00018074828,0.00018133994],"domain_scores_gemma":[0.9995831,0.000046336692,0.000076915174,0.00019081081,0.000034277447,0.00006850695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010210825,0.000093479764,0.00011864396,0.00008324442,0.000034183377,0.00002246114,0.0001777643,0.000049175527,0.000040804345],"category_scores_gemma":[0.00032489793,0.00008501529,0.0000441582,0.00018789849,0.00007683135,0.00011170183,0.00005220098,0.000060232764,0.00015173941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026418973,0.000076094046,0.002311162,0.000015565536,0.000001932388,0.0000054322677,0.00047672132,0.000048585884,0.99418473,0.00059250265,0.0013038989,0.0009569545],"study_design_scores_gemma":[0.00080986694,0.00006149575,0.0097754765,0.000016797974,0.0000045806205,0.000018202289,0.0001719054,0.00005227604,0.9860151,0.0013393621,0.0016127172,0.00012222891],"about_ca_topic_score_codex":0.0001025967,"about_ca_topic_score_gemma":0.00007201279,"teacher_disagreement_score":0.008169641,"about_ca_system_score_codex":0.000024665705,"about_ca_system_score_gemma":0.000042298063,"threshold_uncertainty_score":0.34668228},"labels":[],"label_agreement":null},{"id":"W2203156848","doi":"10.4103/2347-8659.167300","title":"The role of anti-glutamic acid decarboxylase autoantibodies in mood disorders","year":2015,"lang":"en","type":"article","venue":"Neuroimmunology and Neuroinflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Glutamate decarboxylase; Autoantibody; Mood; Glutamic acid; Mood disorders; Psychiatry; Biochemistry; Immunology; Enzyme; Antibody; Amino acid","score_opus":0.012647916207232846,"score_gpt":0.23299722492924016,"score_spread":0.2203493087220073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2203156848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951611,0.00067572424,0.000007981604,0.00091200846,0.00024220158,0.00023612306,0.000002263937,0.000064392465,0.002698198],"genre_scores_gemma":[0.99829555,0.0015764105,0.000006937151,0.000050879447,0.000011063356,0.000011142347,0.0000013240859,0.000015322332,0.000031370997],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860805,0.00032930612,0.00031918043,0.0003156611,0.00015232654,0.00027549468],"domain_scores_gemma":[0.9990811,0.000431838,0.00015527647,0.00027738517,0.000022913226,0.00003150277],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017472407,0.00015296308,0.0001754466,0.00014962806,0.00015923734,0.00003285471,0.00025071867,0.00008076508,0.0000026362384],"category_scores_gemma":[0.0013093345,0.0001227896,0.0000394224,0.00028442842,0.00047338268,0.00023181533,0.00011160537,0.00023220247,0.00001448685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011846736,0.000053087897,0.0077446722,0.000007232054,0.0000024699305,0.0000046771597,0.00041613483,0.00008137477,0.96748596,0.009056849,0.0000052911273,0.015023777],"study_design_scores_gemma":[0.0010993896,0.00025107057,0.3874918,0.000017676459,0.000006954329,0.000057558485,0.0005111365,0.005152071,0.5824352,0.02107109,0.0017014027,0.00020467331],"about_ca_topic_score_codex":0.000019720132,"about_ca_topic_score_gemma":0.00011155022,"teacher_disagreement_score":0.38505077,"about_ca_system_score_codex":0.000009298092,"about_ca_system_score_gemma":0.000042363914,"threshold_uncertainty_score":0.50072145},"labels":[],"label_agreement":null},{"id":"W2215672988","doi":"10.1186/s12991-015-0085-8","title":"Serotonin transporter clustering in blood lymphocytes predicts the outcome on anhedonia scores in naïve depressive patients treated with antidepressant medication","year":2015,"lang":"en","type":"article","venue":"Annals of General Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Saskatchewan Health Research Foundation; University of Saskatchewan","keywords":"Anhedonia; Serotonin transporter; Antidepressant; Depression (economics); Internal medicine; Psychiatry; Medicine; Psychology; Major depressive disorder; Clinical psychology; Endocrinology; Serotonin; Schizophrenia (object-oriented programming); Mood; Receptor","score_opus":0.05127268707238723,"score_gpt":0.29867605717815976,"score_spread":0.2474033701057725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2215672988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973949,0.00020042887,0.000010453818,0.001101568,0.00019198611,0.00054034934,0.00003256275,0.00003118387,0.00049655064],"genre_scores_gemma":[0.9976672,0.00009546622,0.00009118912,0.0019752784,0.000047881935,0.00005287508,0.00001351824,0.000023876079,0.000032692868],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981918,0.00015447552,0.00045630065,0.00041960456,0.0004499912,0.00032787077],"domain_scores_gemma":[0.9992447,0.000055312692,0.00021473732,0.00033607264,0.000049800237,0.00009938539],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017980186,0.00021012033,0.00025216935,0.00019039764,0.00004698993,0.00002231772,0.00036131774,0.00008674665,0.0000070432106],"category_scores_gemma":[0.000081191916,0.00013552113,0.000055343833,0.00038228274,0.00014736562,0.00018097101,0.000029830855,0.00015409348,0.0000036821018],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005589485,0.0005693651,0.9934071,0.00003124327,0.00001210636,0.000010069032,0.00053240755,0.0022752753,0.001669789,0.00007310134,0.0003517044,0.0005089016],"study_design_scores_gemma":[0.0044447505,0.00046154822,0.9379358,0.00019101465,0.000009646688,0.0000035864055,0.00007275229,0.00072368,0.055773355,0.00019074691,0.00002052582,0.00017255759],"about_ca_topic_score_codex":0.00052564166,"about_ca_topic_score_gemma":0.0011575836,"teacher_disagreement_score":0.055471253,"about_ca_system_score_codex":0.000013000322,"about_ca_system_score_gemma":0.000097781594,"threshold_uncertainty_score":0.55263907},"labels":[],"label_agreement":null},{"id":"W2218287850","doi":"10.1016/j.jad.2015.12.020","title":"Lipid peroxidation biomarkers in adolescents with or at high-risk for bipolar disorder","year":2015,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; Canadian Institutes of Health Research; National Institutes of Health; Ontario Ministry of Research, Innovation and Science; National Center for Advancing Translational Sciences; J. Willard and Alice S. Marriott Foundation; Ontario Mental Health Foundation; Centre for Addiction and Mental Health Foundation; Mayo Clinic","keywords":"Bipolar disorder; Lipid peroxidation; Psychology; Medicine; Clinical psychology; Psychiatry; Internal medicine; Mood; Oxidative stress","score_opus":0.016062062992516633,"score_gpt":0.2597602124631047,"score_spread":0.24369814947058807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2218287850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99355173,0.00047095475,0.004277593,0.00040851333,0.0004246507,0.0007626478,0.00001852834,0.000023298013,0.00006210264],"genre_scores_gemma":[0.9989394,0.00037028082,0.00029584617,0.00020225816,0.00007312997,0.000025231271,0.000002099282,0.00004540973,0.000046361616],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9980894,0.00032597288,0.00037294845,0.0003462466,0.0004773566,0.00038810435],"domain_scores_gemma":[0.998687,0.00026553523,0.000528559,0.00017436387,0.0001516149,0.00019288655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004966733,0.00025711826,0.00034455548,0.00043553763,0.00013681133,0.000047201756,0.0002972248,0.000097769574,0.000016036809],"category_scores_gemma":[0.0020167637,0.0001779197,0.00013154473,0.0007586429,0.00019149233,0.0005289959,0.000050403054,0.00025721727,0.000010122017],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021565162,0.00251302,0.76488036,0.00021459367,0.00018159043,0.000041296615,0.0033277513,0.003012862,0.022658933,0.00018706727,0.0028621699,0.17855518],"study_design_scores_gemma":[0.095244706,0.022041116,0.74567664,0.0014848555,0.00030663505,0.0002453555,0.013704643,0.0035647172,0.071490854,0.0047474876,0.038960304,0.0025326682],"about_ca_topic_score_codex":0.00020464887,"about_ca_topic_score_gemma":0.0044513824,"teacher_disagreement_score":0.1760225,"about_ca_system_score_codex":0.00025305242,"about_ca_system_score_gemma":0.00019574295,"threshold_uncertainty_score":0.7255355},"labels":[],"label_agreement":null},{"id":"W2226422021","doi":"10.1002/jcp.25301","title":"IDO‐Expressing Fibroblasts Protect Islet Beta Cells From Immunological Attack and Reverse Hyperglycemia in Non‐Obese Diabetic Mice","year":2016,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"University of British Columbia; Michael Smith Health Research BC; Canadian Institutes of Health Research; Health Canada; University of Miami","keywords":"NOD mice; Insulitis; Nod; Islet; CD8; Immune system; Endocrinology; Internal medicine; Beta cell; T cell; Immune tolerance; Immunology; Cancer research; Biology; Diabetes mellitus; Medicine","score_opus":0.016847073492706408,"score_gpt":0.23216295924369584,"score_spread":0.21531588575098942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2226422021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99829024,0.0004192786,0.00023549497,0.0005399848,0.0002583448,0.00016210483,0.000010021269,0.000011301474,0.00007320162],"genre_scores_gemma":[0.9986993,0.00028251228,0.00039767247,0.00034949166,0.00015682052,0.0000037445805,6.0974907e-7,0.000019026134,0.00009081033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981487,0.0004411307,0.0004781404,0.0003694627,0.00017690119,0.0003857027],"domain_scores_gemma":[0.99866664,0.0005886313,0.00038299407,0.00022800485,0.000036394755,0.000097312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017494321,0.00020895818,0.0004684343,0.00014107388,0.00006833139,0.000026160093,0.0003874672,0.00018910084,0.00014646613],"category_scores_gemma":[0.00027122896,0.00013331525,0.00012487404,0.00015321882,0.00037564477,0.00025856638,0.0001616313,0.00039428877,0.000056342837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002990291,0.00011352248,0.00007471723,0.000019211595,0.000009841239,0.000091649075,0.00014371196,0.00003211496,0.9969572,0.000009028018,0.0002424767,0.0020075208],"study_design_scores_gemma":[0.0021371427,0.00036723478,0.0071212337,0.00024423643,0.0000091443835,0.000026997313,0.000050249855,0.000099136385,0.98749685,0.0010929726,0.0011657937,0.00018902594],"about_ca_topic_score_codex":0.000011588501,"about_ca_topic_score_gemma":0.0000018970243,"teacher_disagreement_score":0.009460345,"about_ca_system_score_codex":0.00004103133,"about_ca_system_score_gemma":0.00004442572,"threshold_uncertainty_score":0.5436438},"labels":[],"label_agreement":null},{"id":"W2226830739","doi":"10.1016/j.physbeh.2016.01.002","title":"A two-hit model of suicide-trait-related behaviors in the context of a schizophrenia-like phenotype: Distinct effects of lithium chloride and clozapine","year":2016,"lang":"en","type":"article","venue":"Physiology & Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canada Research Chairs","keywords":"Prepulse inhibition; Impulsivity; Clozapine; Lithium (medication); Schizophrenia (object-oriented programming); Psychology; Population; Context (archaeology); Social isolation; Psychiatry; Anxiety; Poison control; Lithium chloride; Clinical psychology; Medicine; Chemistry; Biology","score_opus":0.018277962102875512,"score_gpt":0.2683105542627238,"score_spread":0.2500325921598483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2226830739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99885726,0.00014142452,0.000010287789,0.00010587456,0.0001262529,0.0006002369,0.00010111189,0.000022486529,0.000035046098],"genre_scores_gemma":[0.9996213,0.000047486297,0.000038530274,0.00010436595,0.000011847042,0.000101419784,0.0000042429483,0.000021800273,0.00004904175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983388,0.00022394948,0.00051367976,0.000419187,0.00019968233,0.00030469734],"domain_scores_gemma":[0.9985019,0.00066484255,0.00031923995,0.00041289066,0.000049644426,0.000051469182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015596658,0.00022467587,0.00051656656,0.00013207197,0.000044766126,0.0000035848586,0.00041650355,0.00012011576,0.000023478664],"category_scores_gemma":[0.00026641975,0.00013700545,0.0001249304,0.00028722023,0.001043598,0.00010048655,0.00011409154,0.00018395089,0.0000030953897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005120609,0.0005826157,0.0030181312,0.00004913024,0.00000574443,0.0000057368406,0.00075106043,0.000005805515,0.98750675,0.0018940812,0.0000096090735,0.005659291],"study_design_scores_gemma":[0.0036709746,0.00035902427,0.3112202,0.00010755496,0.00007580677,0.0000047552435,0.000085762396,0.00006683482,0.6832462,0.0010032151,0.0000030081792,0.00015666605],"about_ca_topic_score_codex":0.00021325554,"about_ca_topic_score_gemma":0.00008294387,"teacher_disagreement_score":0.30820206,"about_ca_system_score_codex":0.000014074405,"about_ca_system_score_gemma":0.000055348457,"threshold_uncertainty_score":0.558692},"labels":[],"label_agreement":null},{"id":"W2237079496","doi":"10.3390/ijms17010080","title":"Obesity and Its Potential Effects on Antidepressant Treatment Outcomes in Patients with Depressive Disorders: A Literature Review","year":2016,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Mental Health; H. Lundbeck A/S; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; Sunovion; Brain and Behavior Research Foundation","keywords":"Antidepressant; Obesity; Neurocognitive; Major depressive disorder; Medicine; Depression (economics); Internal medicine; Psychiatry; Psychology; Clinical psychology; Cognition","score_opus":0.012076124152757802,"score_gpt":0.30273719848665437,"score_spread":0.29066107433389654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2237079496","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014541972,0.9839403,0.00003430238,0.00030908926,0.00042975182,0.0006097217,0.00004342801,0.000006027413,0.000085378975],"genre_scores_gemma":[0.025821589,0.9737058,0.000034983514,0.00035044595,0.00003838183,0.000014739902,0.0000024001129,0.000013985502,0.000017674125],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9974326,0.00036427873,0.00047786348,0.00044545796,0.0010677079,0.00021211515],"domain_scores_gemma":[0.9985861,0.0003323755,0.000749709,0.00012539892,0.00011762912,0.000088769084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001807754,0.0003396023,0.0008359504,0.00046693077,0.00006288987,0.00015759493,0.00083119335,0.00008208769,0.000008363941],"category_scores_gemma":[0.00046719494,0.00016531092,0.00029635767,0.0002887629,0.00013401933,0.00033297454,0.00009634023,0.00020805404,0.0000053789367],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006402832,0.00077285036,0.0011733044,0.0021819256,0.00017979184,0.0012055618,0.000042631433,0.0000086547125,0.00003909663,0.00035476757,0.000026563888,0.99395084],"study_design_scores_gemma":[0.014092577,0.008224407,0.01744359,0.83269703,0.00082634174,0.0009986765,0.000013275367,0.000017522096,0.0029242395,0.0012428033,0.11913328,0.0023862529],"about_ca_topic_score_codex":0.0000011770835,"about_ca_topic_score_gemma":0.0000015591872,"teacher_disagreement_score":0.9915646,"about_ca_system_score_codex":0.000081898936,"about_ca_system_score_gemma":0.00015240263,"threshold_uncertainty_score":0.6741184},"labels":[],"label_agreement":null},{"id":"W2247106978","doi":"10.1159/000358027","title":"Proteomic and Metabolomic Evidence for Glial Alterations in Schizophrenia","year":2014,"lang":"en","type":"book-chapter","venue":"Advances in biological psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of British Columbia","funders":"","keywords":"Microglia; Oligodendrocyte; Astrocyte; Grey matter; Schizophrenia (object-oriented programming); White matter; Neuroscience; Biology; Neuroglia; Neuroinflammation; Central nervous system; Medicine; Immunology; Myelin; Psychiatry; Inflammation; Magnetic resonance imaging","score_opus":0.05796424552748295,"score_gpt":0.3261223157069631,"score_spread":0.2681580701794801,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2247106978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.65098804,0.15179113,0.008659288,0.009817524,0.015290622,0.01855759,0.0008429529,0.0007757059,0.14327712],"genre_scores_gemma":[0.90705675,0.03875511,0.028911233,0.00585839,0.0017560833,0.0010309019,0.000051043804,0.00013112143,0.01644936],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9980491,0.000080349484,0.0004879496,0.0009438734,0.00011381149,0.00032493257],"domain_scores_gemma":[0.99888635,0.00057592057,0.00020147269,0.0002580208,0.000013274911,0.000064979344],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021010074,0.00034396184,0.00047322837,0.00018477351,0.00009253292,0.00003614462,0.00036217476,0.0003637262,0.000058702066],"category_scores_gemma":[0.0006643909,0.0002674595,0.00011310144,0.00007074793,0.00041242232,0.00019370842,0.00008793351,0.0004564805,0.00002737656],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019490957,0.00008132432,0.0014785595,0.00017221279,0.0000054106326,0.000004021204,0.00003027731,0.00005604406,0.007719074,0.95955855,0.00022490669,0.028720528],"study_design_scores_gemma":[0.002902717,0.0007621601,0.0037563688,0.0008424385,0.000012853534,0.00001527295,0.000009911222,0.00016611787,0.00077817944,0.92588073,0.06392113,0.00095212925],"about_ca_topic_score_codex":0.0000024792694,"about_ca_topic_score_gemma":0.00012804911,"teacher_disagreement_score":0.25606868,"about_ca_system_score_codex":0.000030083958,"about_ca_system_score_gemma":0.00006307295,"threshold_uncertainty_score":0.99997777},"labels":[],"label_agreement":null},{"id":"W2253752583","doi":"10.1093/schbul/sbv118","title":"Elevated Myo-Inositol, Choline, and Glutamate Levels in the Associative Striatum of Antipsychotic-Naive Patients With First-Episode Psychosis: A Proton Magnetic Resonance Spectroscopy Study With Implications for Glial Dysfunction","year":2015,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Glutamate receptor; Psychosis; Glutamatergic; Choline; Internal medicine; Antipsychotic; Endocrinology; Schizophrenia (object-oriented programming); Neuroscience; Psychology; Striatum; Medicine; Psychiatry; Dopamine; Receptor","score_opus":0.023197426628324688,"score_gpt":0.2655127902210914,"score_spread":0.24231536359276673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2253752583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908737,0.00008709102,0.00016949615,0.0025073176,0.00009308423,0.0059152623,0.00022219669,0.000047971633,0.00008388784],"genre_scores_gemma":[0.9968765,0.000015487027,0.001571575,0.00021565506,0.00004535457,0.0011890995,0.000009804018,0.00003395061,0.000042586053],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9978913,0.00028565447,0.00037762645,0.0006475724,0.00041495202,0.00038286706],"domain_scores_gemma":[0.99867886,0.00032281107,0.00032328363,0.0003877148,0.00020501776,0.00008228701],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034128517,0.00027927448,0.00032016877,0.00012931362,0.00020810269,0.00008672427,0.00033455092,0.00007581573,0.000009829746],"category_scores_gemma":[0.00047555592,0.00018659554,0.000036807673,0.00069837616,0.00017369537,0.00010365538,0.00003356987,0.00023824364,0.0000063671855],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.048021395,0.0059216763,0.9266919,0.00013848487,0.000056241515,0.000006284681,0.005458405,0.000041677693,0.0036307673,0.0007926425,0.00647269,0.0027678676],"study_design_scores_gemma":[0.020255044,0.0067583537,0.965644,0.00012856258,0.000041536474,0.0000034947473,0.0005833249,0.000049301187,0.0041704834,0.00065811316,0.0014071023,0.0003006626],"about_ca_topic_score_codex":0.00011907709,"about_ca_topic_score_gemma":0.00067442475,"teacher_disagreement_score":0.03895215,"about_ca_system_score_codex":0.000054750853,"about_ca_system_score_gemma":0.00005926883,"threshold_uncertainty_score":0.76091456},"labels":[],"label_agreement":null},{"id":"W2257952977","doi":"10.1016/j.pnpbp.2016.01.008","title":"Neuropathological relationship between major depression and dementia: A hypothetical model and review","year":2016,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":105,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Mitacs; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Excitotoxicity; Neurodegeneration; Neuroscience; Neurotrophic factors; Neurogenesis; Major depressive disorder; Brain-derived neurotrophic factor; Psychology; Medicine; Glutamate receptor; Internal medicine; Amygdala; Receptor","score_opus":0.09650358469682994,"score_gpt":0.38771710112107,"score_spread":0.29121351642424004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2257952977","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020756485,0.9745636,0.00001847122,0.0021128128,0.00049365347,0.0016758139,0.00008157592,0.00012910961,0.00016849364],"genre_scores_gemma":[0.025337234,0.9682923,0.000352733,0.0053764624,0.00017643122,0.00039630118,0.0000093086455,0.00004506325,0.000014185005],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99438834,0.0018011378,0.0009974722,0.0019349608,0.0001903399,0.0006877652],"domain_scores_gemma":[0.9965383,0.0024118884,0.00039678405,0.0003069332,0.000015424162,0.0003307035],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055125385,0.00073890656,0.0015953432,0.00024292654,0.00028410155,0.0000521315,0.0004800635,0.00088905264,0.000051004634],"category_scores_gemma":[0.00070589554,0.00043518978,0.0002086636,0.00038965276,0.0016779866,0.00011341512,0.0005316343,0.001435532,0.000021091088],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016713032,0.0003174424,0.26238245,0.006913714,0.000025033216,0.00009740674,0.0000063287184,3.12014e-8,0.0000071021436,0.0018745104,0.0008836137,0.72732526],"study_design_scores_gemma":[0.008900168,0.0015777578,0.4299242,0.027098514,0.0016107677,0.002032645,0.0000057410607,0.000056405293,0.0000022431423,0.03729534,0.48837575,0.003120447],"about_ca_topic_score_codex":1.10636215e-7,"about_ca_topic_score_gemma":2.787993e-7,"teacher_disagreement_score":0.7242048,"about_ca_system_score_codex":0.000012176135,"about_ca_system_score_gemma":0.000063166604,"threshold_uncertainty_score":0.99981},"labels":[],"label_agreement":null},{"id":"W2263491442","doi":"10.1159/000441521","title":"Inflammatory Cytokines and Antipsychotic-Induced Weight Gain: Review and Clinical Implications","year":2016,"lang":"en","type":"review","venue":"Complex Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; St. Michael's Hospital; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Clozapine; Antipsychotic; Cytokine; Immune system; Medicine; Schizophrenia (object-oriented programming); Neuroinflammation; Inflammation; Weight gain; Olanzapine; Immunology; Proinflammatory cytokine; Obesity; Psychosis; Internal medicine; Body weight; Psychiatry","score_opus":0.13113788702030404,"score_gpt":0.40408565981867417,"score_spread":0.2729477727983701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2263491442","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000047456153,0.99069434,0.000023769377,0.004191494,0.0011097975,0.0014391167,0.00013583346,0.00015723197,0.0022009679],"genre_scores_gemma":[0.000032373948,0.9948098,0.00025789443,0.003957648,0.00055339764,0.0000958853,0.000017667524,0.00008532178,0.00018999162],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99631757,0.00054443436,0.0012582781,0.0012583163,0.00018167288,0.0004397209],"domain_scores_gemma":[0.99726135,0.00066715264,0.00064242975,0.0010762089,0.00003987512,0.00031295972],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033409795,0.0006053316,0.0017885637,0.00017867536,0.00027705097,0.00008139533,0.00066168,0.00033763782,0.00019668131],"category_scores_gemma":[0.0003254186,0.00042641663,0.00045008652,0.00039166695,0.00044999708,0.00013348089,0.00023640155,0.0004970149,0.0002475379],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000537373,0.00011536917,0.0002797187,0.027238313,0.00005253009,0.000002557409,0.0000041690555,5.9020067e-10,0.00002039403,0.015221566,0.047965713,0.9090943],"study_design_scores_gemma":[0.0004247464,0.000054170883,0.0016827586,0.015845865,0.00032961663,0.0001715946,0.0000013999603,3.9207276e-7,4.0165654e-7,0.0025965697,0.9783471,0.0005453899],"about_ca_topic_score_codex":5.4450146e-7,"about_ca_topic_score_gemma":0.0000054333923,"teacher_disagreement_score":0.93038136,"about_ca_system_score_codex":0.000018804336,"about_ca_system_score_gemma":0.0002638245,"threshold_uncertainty_score":0.99981874},"labels":[],"label_agreement":null},{"id":"W2267633038","doi":"10.2174/1566524016666160126144722","title":"Nitric Oxide and Major Depressive Disorder: Pathophysiology and Treatment Implications","year":2016,"lang":"en","type":"review","venue":"Current Molecular Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"AstraZeneca","keywords":"Neuroinflammation; Major depressive disorder; Nitric oxide; Neuroprotection; Inflammation; Tetrahydrobiopterin; Microglia; Neuroscience; Biology; Nitric oxide synthase; Medicine; Internal medicine; Immunology; Amygdala","score_opus":0.04175321178978796,"score_gpt":0.34228546202697685,"score_spread":0.3005322502371889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2267633038","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013546248,0.99637675,0.00045186514,0.0003548682,0.0001495561,0.001022849,0.0000918705,0.000053217154,0.00014442556],"genre_scores_gemma":[0.0004960217,0.998677,0.000013735676,0.00017160068,0.00010157586,0.00037912262,0.00005353356,0.000046605997,0.000060780727],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997959,0.00027154805,0.00040117936,0.00088027824,0.00014628681,0.00034168674],"domain_scores_gemma":[0.9985565,0.00044176966,0.00027253796,0.0004912698,0.000022741227,0.00021517507],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000047280955,0.00048931345,0.0010802324,0.00026116782,0.00014349775,0.000014962133,0.00022677866,0.00014353452,0.000032290223],"category_scores_gemma":[0.00043700825,0.00028107912,0.00014452948,0.00029649367,0.0005121777,0.000038427672,0.00014267529,0.00018393445,0.000030376188],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000029130217,0.0000661237,0.0000045506736,0.0010146883,0.00002172325,0.000017768627,0.000020727126,1.37322385e-8,0.0038815134,0.0011960373,0.00015136048,0.9936226],"study_design_scores_gemma":[0.0012905207,0.00015004589,0.000129525,0.0037125803,0.00036251542,0.000076754564,0.000007205412,0.0000011872872,0.00009514388,0.0018733917,0.99195236,0.00034879585],"about_ca_topic_score_codex":0.0000060274024,"about_ca_topic_score_gemma":0.0000011838778,"teacher_disagreement_score":0.9932738,"about_ca_system_score_codex":0.00004867926,"about_ca_system_score_gemma":0.000084692285,"threshold_uncertainty_score":0.9999641},"labels":[],"label_agreement":null},{"id":"W2275844848","doi":"10.2174/1570159x13666150630171433","title":"The Involvement of TNF-&amp;#945; in Cognitive Dysfunction Associated with Major Depressive Disorder: An Opportunity for Domain Specific Treatments","year":2015,"lang":"en","type":"review","venue":"Current Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":139,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Major depressive disorder; Adalimumab; Medicine; Cognition; Comorbidity; Clinical psychology; Infliximab; Etanercept; Psychiatry; Bioinformatics; Disease; Internal medicine; Tumor necrosis factor alpha","score_opus":0.2044859349534796,"score_gpt":0.4030462794623671,"score_spread":0.1985603445088875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2275844848","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.038416155,0.95035386,0.00014090005,0.000050782754,0.0025370044,0.0070845783,0.0011683942,0.000088518325,0.00015981146],"genre_scores_gemma":[0.0019741533,0.9953043,0.000007284,0.00010295034,0.00011079916,0.0016504551,0.00059185876,0.00009991131,0.00015828024],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948312,0.0022268381,0.00084951904,0.0010219694,0.00040492375,0.00066556677],"domain_scores_gemma":[0.99574286,0.0023064732,0.0011287224,0.00035887104,0.00018777592,0.0002752788],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004379672,0.0006451927,0.0012888608,0.00030181318,0.000298583,0.00004765532,0.00062552094,0.0001942863,0.000058131838],"category_scores_gemma":[0.0005453127,0.0004282985,0.00027228813,0.00068919925,0.00053841947,0.00015180472,0.00016451563,0.00063145056,0.000019126575],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006727573,0.002677697,0.00006632843,0.0011101176,0.00016078257,0.000043830863,0.00022965082,0.0000043729156,0.00022394369,0.00013415121,0.0017890362,0.9928873],"study_design_scores_gemma":[0.007147128,0.0010707561,0.000109251756,0.0010538178,0.0005235569,0.000011978472,0.00010765191,0.000009379888,0.00011916767,0.0002823437,0.9890994,0.0004656024],"about_ca_topic_score_codex":0.000006578359,"about_ca_topic_score_gemma":0.000103074206,"teacher_disagreement_score":0.99242175,"about_ca_system_score_codex":0.00024883033,"about_ca_system_score_gemma":0.0006335112,"threshold_uncertainty_score":0.9998169},"labels":[],"label_agreement":null},{"id":"W2276998540","doi":"","title":"PDEs as drug targets for CNS immune disorders.","year":2008,"lang":"en","type":"article","venue":"PubMed","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Neuroinflammation; Immune system; Neuroscience; Signal transduction; Microglia; Central nervous system; Neuroimmunology; Medicine; Immunology; Biology; Inflammation; Cell biology","score_opus":0.026257522662819548,"score_gpt":0.22670169401910495,"score_spread":0.2004441713562854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2276998540","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95478314,0.0008648451,0.00034864852,0.0054443423,0.00090234785,0.0021870472,0.00003295029,0.00036423674,0.035072446],"genre_scores_gemma":[0.9870454,0.00023939386,0.000084426094,0.0012613698,0.00007461202,0.0015569094,0.000003961041,0.000027340398,0.009706591],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987085,0.00004066016,0.00016901799,0.00035480177,0.00018485141,0.0005421817],"domain_scores_gemma":[0.99936384,0.00021860428,0.00005882591,0.00023374877,0.000014085947,0.000110889465],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107018706,0.00014006704,0.00014863674,0.000072350274,0.00028938887,0.000027628439,0.00030897243,0.000041991578,0.00005409228],"category_scores_gemma":[0.0008331468,0.00012778208,0.00012898337,0.00020213198,0.0001872804,0.00017414414,0.000055286207,0.00008732921,0.000088714565],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010214822,0.0028195542,0.009301122,0.0002749513,0.0000896931,0.00010747511,0.007390046,0.00014096021,0.068648905,0.037524126,0.18867184,0.68400985],"study_design_scores_gemma":[0.002969042,0.000058643385,0.31464505,0.0000051929846,0.000009977112,0.00003600323,0.0002218431,0.00009993803,0.30722734,0.01884711,0.35520184,0.0006780067],"about_ca_topic_score_codex":0.00003296834,"about_ca_topic_score_gemma":0.000019999106,"teacher_disagreement_score":0.68333185,"about_ca_system_score_codex":0.000019236391,"about_ca_system_score_gemma":0.00002381269,"threshold_uncertainty_score":0.52108026},"labels":[],"label_agreement":null},{"id":"W227878633","doi":"10.1177/070674370204700306","title":"Relation of Blood Counts during Clozapine Treatment to Serum Concentrations of Clozapine and Nor-Clozapine","year":2002,"lang":"en","type":"article","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Western University; Queen's University","funders":"","keywords":"Clozapine; Hematocrit; Medicine; White blood cell; Hemoglobin; Toxicity; Schizophrenia (object-oriented programming); Internal medicine; Anesthesia; Pharmacology; Gastroenterology; Psychiatry","score_opus":0.020745453905851582,"score_gpt":0.22718055565421508,"score_spread":0.2064351017483635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W227878633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883675,0.0028021303,0.000009498778,0.0069246422,0.0005536479,0.00013078739,0.000050784653,0.0000036736037,0.0011573237],"genre_scores_gemma":[0.99826914,0.00056968856,0.00028752425,0.00026564917,0.0001191322,8.509883e-7,4.3542641e-7,0.000008890656,0.00047869707],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99929947,0.000044248653,0.00029406778,0.00008703036,0.00013013298,0.00014502663],"domain_scores_gemma":[0.9993991,0.000028371911,0.00020092248,0.00013588434,0.000046677433,0.00018899649],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000071135655,0.00008249492,0.0001386576,0.00013033471,0.00012868247,0.000014391984,0.00013286658,0.000035535904,0.0003653592],"category_scores_gemma":[0.00006190729,0.0000619776,0.000053393287,0.00021489442,0.00010684621,0.00006556084,0.000005153706,0.00008557831,0.000009821136],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008231332,0.0019588133,0.34319186,0.00062842516,0.00096826244,0.00020305406,0.023020871,0.0039667725,0.3444444,0.19327429,0.043634392,0.043885745],"study_design_scores_gemma":[0.018418793,0.003954265,0.7923267,0.00090922235,0.00061306224,0.0014429535,0.0013104735,0.0007216473,0.10811852,0.009116101,0.062059056,0.0010092446],"about_ca_topic_score_codex":0.00047523412,"about_ca_topic_score_gemma":0.016627017,"teacher_disagreement_score":0.4491348,"about_ca_system_score_codex":0.00003487597,"about_ca_system_score_gemma":0.00022159287,"threshold_uncertainty_score":0.9278266},"labels":[],"label_agreement":null},{"id":"W2281819675","doi":"10.1016/j.neubiorev.2016.02.002","title":"T helper 17 cells may drive neuroprogression in major depressive disorder: Proposal of an integrative model","year":2016,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":90,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University","funders":"","keywords":"Pathophysiology; Serotonergic; Major depressive disorder; Neuroscience; Dopaminergic; Psychology; Monoamine neurotransmitter; Autoimmunity; Neuroinflammation; Immune system; Inflammation; Medicine; Immunology; Dopamine; Serotonin; Cognition; Internal medicine; Receptor","score_opus":0.07488915475554757,"score_gpt":0.3852312709168516,"score_spread":0.310342116161304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2281819675","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004200943,0.9883154,0.00016138221,0.000011964711,0.00083756767,0.005767206,0.00039332747,0.00012253204,0.00018968675],"genre_scores_gemma":[0.0009508379,0.9965996,0.00046174874,0.00032465963,0.000056082135,0.0007766592,0.00001617215,0.00014087535,0.000673356],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99140793,0.0015344509,0.0021166448,0.0027312832,0.0010405185,0.0011691594],"domain_scores_gemma":[0.99594223,0.00003504374,0.0019207571,0.0015850291,0.0000833879,0.00043352292],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00059412327,0.0013877447,0.003135908,0.0007300889,0.0002780796,0.00016733615,0.0028189418,0.0004774973,0.000101942744],"category_scores_gemma":[0.0008188805,0.00080813054,0.00096737355,0.0019008969,0.0019988262,0.0010982573,0.00068244885,0.0011264457,0.000115427945],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018555096,0.000702993,0.000013663602,0.001410761,8.9312756e-8,0.000082227794,0.00012806617,0.0000034274274,0.045769338,0.0001187377,0.0002503176,0.95150185],"study_design_scores_gemma":[0.0006279256,0.0007373215,0.000012043793,0.014926657,0.00012313739,0.00005862065,0.000037444566,0.00026531084,0.0042420854,0.000107094376,0.97772247,0.0011399187],"about_ca_topic_score_codex":0.000025469042,"about_ca_topic_score_gemma":0.00006239348,"teacher_disagreement_score":0.9774721,"about_ca_system_score_codex":0.00013613873,"about_ca_system_score_gemma":0.0007454944,"threshold_uncertainty_score":0.9998873},"labels":[],"label_agreement":null},{"id":"W2284757052","doi":"10.1016/j.neubiorev.2016.02.017","title":"Mapping inflammation onto mood: Inflammatory mediators of anhedonia","year":2016,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":125,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Sunnybrook Health Science Centre; Toronto Rehabilitation Institute; University of Toronto","funders":"","keywords":"Anhedonia; Research Domain Criteria; Neuroscience; Psychology; Mood; Nucleus accumbens; Dopaminergic; Cognition; Dopamine; Clinical psychology","score_opus":0.10393492790590751,"score_gpt":0.3596775397534409,"score_spread":0.2557426118475334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2284757052","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012135489,0.9934772,0.000060813247,0.000007545362,0.0016299743,0.0028653613,0.0001015241,0.00017633119,0.0004676981],"genre_scores_gemma":[0.00030231618,0.9985194,0.00007925891,0.00016356244,0.00021532986,0.00036706813,0.000008551845,0.00009592352,0.00024855547],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9931564,0.00074126094,0.0024955224,0.0015924615,0.0010950208,0.00091934914],"domain_scores_gemma":[0.9956218,0.000038387527,0.0025184748,0.001378462,0.00006984992,0.0003730526],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009904167,0.0010034222,0.0026358603,0.0007926579,0.00025476958,0.00013900129,0.0020912213,0.0004500401,0.00018463082],"category_scores_gemma":[0.0022298347,0.000679256,0.0011332475,0.0018945985,0.0009454702,0.00080833724,0.0004405057,0.0005848107,0.0005886876],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002305264,0.000058321635,0.000025878595,0.0037110783,8.7428695e-8,0.00001231518,0.00006654992,5.7425506e-8,0.023776555,0.00018857118,0.0003368785,0.9718214],"study_design_scores_gemma":[0.000197151,0.0000958809,0.00006058763,0.0097624445,0.000060280992,0.000036286514,0.000009173423,0.0000015657846,0.0007038005,0.000032510918,0.9883654,0.00067487755],"about_ca_topic_score_codex":0.000007362305,"about_ca_topic_score_gemma":0.000008879944,"teacher_disagreement_score":0.9880286,"about_ca_system_score_codex":0.00018608979,"about_ca_system_score_gemma":0.0005373434,"threshold_uncertainty_score":0.99956584},"labels":[],"label_agreement":null},{"id":"W2292886270","doi":"10.3233/jhd-159003","title":"Indoleamine 2,3 Dioxygenase as a Potential Therapeutic Target in Huntington’s Disease","year":2015,"lang":"en","type":"review","venue":"Journal of Huntington s Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Quinolinic acid; Kynurenine; Indoleamine 2,3-dioxygenase; Kynurenine pathway; Kynurenic acid; Neuroprotection; Metabolite; Huntington's disease; Neurodegeneration; Tryptophan; Enzyme; Catabolism; Pharmacology; Biochemistry; Disease; Biology; Chemistry; Medicine; Amino acid; Internal medicine","score_opus":0.0429775877604345,"score_gpt":0.32539238041221924,"score_spread":0.28241479265178476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2292886270","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010778862,0.9861441,0.000027222637,0.00024326172,0.0011037134,0.00096717937,0.00015386002,0.000071962335,0.0005098273],"genre_scores_gemma":[0.031503875,0.965246,0.000068964284,0.0010223014,0.0011545216,0.000048212685,0.00003212579,0.00023327222,0.0006907009],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99313706,0.0010792665,0.0021980517,0.00090114394,0.001708488,0.00097601727],"domain_scores_gemma":[0.9942899,0.00036320832,0.0025528627,0.0007749389,0.00024402184,0.0017751055],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011395458,0.0009706096,0.0023624266,0.0013361098,0.00016497177,0.00035671063,0.0015992203,0.00026655072,0.00045872765],"category_scores_gemma":[0.0035834815,0.0007752348,0.0017691093,0.0012052839,0.00027424996,0.0006764771,0.00033518006,0.0014796718,0.000282834],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018936987,0.004235319,0.00029237592,0.017302308,0.00025167406,0.0038666225,0.0003023225,0.00017735278,0.0003205531,0.0005555563,0.0040830807,0.96671915],"study_design_scores_gemma":[0.0024763297,0.00019841178,0.00048165163,0.00804475,0.0006610254,0.000055267923,0.00009886056,0.000043288597,0.0001540031,0.0022712732,0.9843339,0.0011812501],"about_ca_topic_score_codex":0.000009124785,"about_ca_topic_score_gemma":0.0000018680239,"teacher_disagreement_score":0.98025084,"about_ca_system_score_codex":0.00030765543,"about_ca_system_score_gemma":0.0031187418,"threshold_uncertainty_score":0.9994699},"labels":[],"label_agreement":null},{"id":"W2293592800","doi":"10.1016/j.schres.2016.03.002","title":"Quantitative mass spectrometry reveals changes in SNAP-25 isoforms in schizophrenia","year":2016,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Mental Health & Substance Use Services","funders":"National Institute of Mental Health","keywords":"Schizophrenia (object-oriented programming); Snap; Mass spectrometry; Gene isoform; Chemistry; Psychology; Psychiatry; Chromatography; Computer science; Biochemistry","score_opus":0.08307855905217913,"score_gpt":0.36191518491604996,"score_spread":0.2788366258638708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2293592800","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98551786,0.00034074407,0.000096001546,0.007797811,0.00022416847,0.00086749386,0.000059701808,0.00011144103,0.004984797],"genre_scores_gemma":[0.99425745,0.00068885833,0.0025811899,0.00020252314,0.0001369331,0.00017758441,0.0000028557704,0.00006715671,0.0018854291],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99381655,0.0011317529,0.00054157426,0.0012742263,0.0014313658,0.0018045128],"domain_scores_gemma":[0.996309,0.0024112961,0.00010808949,0.00078274007,0.00010780234,0.0002810921],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0025661443,0.00036234618,0.00050130486,0.0028487465,0.0002327776,0.00015130905,0.0012410515,0.00024155597,0.0007640445],"category_scores_gemma":[0.0054920684,0.00025622864,0.00010144717,0.004645021,0.0007773782,0.00055551046,0.00037940353,0.0011003974,0.0014013893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028891275,0.00020079112,0.002357713,0.000046714384,0.000005424785,0.00019417929,0.0002779676,0.0000013621893,0.9157688,0.06441465,0.00072790217,0.013115388],"study_design_scores_gemma":[0.015744863,0.0015981488,0.13493317,0.0009007508,0.0000031942939,0.000030971547,0.0011675481,0.00016335754,0.57381934,0.26911807,0.0013188109,0.0012017568],"about_ca_topic_score_codex":0.0001281203,"about_ca_topic_score_gemma":0.0023040792,"teacher_disagreement_score":0.34194943,"about_ca_system_score_codex":0.0003888096,"about_ca_system_score_gemma":0.00028353292,"threshold_uncertainty_score":0.999989},"labels":[],"label_agreement":null},{"id":"W2296605000","doi":"10.1159/000445191","title":"Increased Activity of the Immunoregulatory Enzyme Indoleamine-2,3-Dioxygenase with Consecutive Tryptophan Depletion Predicts Death in Patients with Neuroendocrine Neoplasia","year":2016,"lang":"en","type":"article","venue":"Neuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Medicine; Proportional hazards model; Internal medicine; Tryptophan; Endocrinology; Cohort; Retrospective cohort study; Kynurenine; Gastroenterology; Biology; Amino acid; Biochemistry","score_opus":0.010253097163547819,"score_gpt":0.20783118164573922,"score_spread":0.19757808448219139,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2296605000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997881,0.000022942297,0.000027798402,0.0005541517,0.00017706462,0.0009135636,0.000083798215,0.00010222432,0.0002374458],"genre_scores_gemma":[0.9990904,0.00005672186,0.000015188395,0.00063028914,0.000020006022,0.00006582149,0.0000025354138,0.000054809898,0.000064238295],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99686223,0.0007268352,0.00035712868,0.0008123576,0.00047898229,0.00076245354],"domain_scores_gemma":[0.9981072,0.0005415385,0.00034607152,0.00080383883,0.00008418092,0.00011717484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000015424603,0.00039795233,0.0004401273,0.00027093495,0.00012979264,0.000014795128,0.0005801546,0.00004243604,0.000038246544],"category_scores_gemma":[0.0004885258,0.00021850133,0.00008286555,0.0005724187,0.00085124874,0.00027124162,0.00021809433,0.00036226824,0.000010074133],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00801222,0.0011365121,0.68776983,0.00004593739,0.000030220785,0.0004429805,0.00008112719,0.00003280582,0.296952,0.0013580642,0.000105473824,0.004032803],"study_design_scores_gemma":[0.0060222256,0.0010198909,0.5936909,0.00004408712,0.000007120414,0.00014200248,0.0000075741173,0.000008386535,0.3986633,0.00003972101,0.00020686946,0.0001479287],"about_ca_topic_score_codex":0.000106207895,"about_ca_topic_score_gemma":0.00018088428,"teacher_disagreement_score":0.10171129,"about_ca_system_score_codex":0.00007406513,"about_ca_system_score_gemma":0.00017372858,"threshold_uncertainty_score":0.89102256},"labels":[],"label_agreement":null},{"id":"W2299031941","doi":"10.1111/bdi.12373","title":"Anti‐inflammatory agents in the treatment of bipolar depression: a systematic review and meta‐analysis","year":2016,"lang":"en","type":"review","venue":"Bipolar Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":197,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; Western University; University of Toronto; Health Sciences Centre; University Health Network","funders":"National Institute of Mental Health; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; AstraZeneca; Fundação de Amparo à Pesquisa do Estado de São Paulo; National Health and Medical Research Council; National Institutes of Health; Sunovion; H. Lundbeck A/S; Servier; Medical Research Council; Geelong Region Medical Research Foundation; Beyond Blue; GlaxoSmithKline; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Australian Rotary Health; Canadian Institutes of Health Research; Bristol-Myers Squibb; Eli Lilly and Company; Shire; Stanley Medical Research Institute; Sanofi; Novartis; Pfizer; Cilag; Brain and Behavior Research Foundation","keywords":"Bipolar disorder; Adjunctive treatment; Randomized controlled trial; Medicine; Internal medicine; Meta-analysis; Antidepressant; Depression (economics); Mood; Mood disorders; Confidence interval; Adverse effect; Psychiatry; Anxiety","score_opus":0.0691242161692713,"score_gpt":0.33345100135635575,"score_spread":0.26432678518708447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2299031941","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000062793315,0.99520147,0.000011326593,0.00010125539,0.00003766089,0.0043687806,0.00017744642,0.000033484186,0.00006230941],"genre_scores_gemma":[0.00006113413,0.9985216,0.0000066680577,0.0002495421,0.00000942134,0.0009129823,0.00001373539,0.00005055839,0.00017431701],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.99492353,0.0021075762,0.0012162196,0.00082242826,0.0005140524,0.00041619746],"domain_scores_gemma":[0.99666595,0.0010467232,0.00091949117,0.0012562239,0.000018521563,0.00009308653],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055079965,0.0007114733,0.0055557224,0.00061723485,0.00012781951,0.00004814523,0.000862329,0.00021588668,0.00016628247],"category_scores_gemma":[0.00030677122,0.0003249875,0.0025096533,0.0016099341,0.00023454685,0.00012487896,0.000074787866,0.00016368271,0.000052933687],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000025634486,0.00051298394,0.000046133562,0.86000925,0.022625145,0.000018402714,0.00028746342,3.901181e-7,0.0000027133642,0.00013576806,0.00007607463,0.116283104],"study_design_scores_gemma":[0.00022061105,0.00005371088,0.000021230442,0.019185444,0.27882063,0.000011930115,0.000022856246,0.0000013271157,0.0000039458387,0.000021558524,0.7012657,0.00037106712],"about_ca_topic_score_codex":0.000037282934,"about_ca_topic_score_gemma":0.00010541356,"teacher_disagreement_score":0.8408238,"about_ca_system_score_codex":0.00004979753,"about_ca_system_score_gemma":0.000089734815,"threshold_uncertainty_score":0.9999202},"labels":[],"label_agreement":null},{"id":"W2304968738","doi":"10.1093/ijnp/pyw001","title":"Stress-Related Immune Markers in Depression: Implications for Treatment","year":2016,"lang":"en","type":"review","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"Depression (economics); Immune system; Endocrine system; Inflammation; Psychoneuroimmunology; Major depressive disorder; Immune dysregulation; Psychology; Medicine; Pathogenesis; Bioinformatics; Clinical psychology; Psychiatry; Immunology; Internal medicine; Hormone; Biology; Mood","score_opus":0.0610109265096613,"score_gpt":0.4040255342627093,"score_spread":0.34301460775304804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2304968738","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011394655,0.9858303,0.000043156746,0.0047082873,0.006000327,0.0010926961,0.0002950698,0.000021147505,0.000869551],"genre_scores_gemma":[0.0027854748,0.995557,0.000016964936,0.00054795516,0.00041678193,0.00013323016,0.000005943104,0.000047411162,0.00048925413],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99759775,0.0004661151,0.0011262865,0.00032778477,0.00022012947,0.00026196],"domain_scores_gemma":[0.99579567,0.002509583,0.0012629258,0.00023375676,0.00012189868,0.00007615574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024243965,0.00029921575,0.0007355341,0.0004471801,0.00007465209,0.000042039403,0.0018253905,0.00013276236,0.00025812042],"category_scores_gemma":[0.0003149399,0.00015952556,0.00065429904,0.00022370175,0.00015558225,0.00010887791,0.00009716524,0.00029017054,0.000038645885],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035039673,0.00030073593,0.0000060989496,0.00007696888,0.0001955202,0.00008334928,0.000031709944,0.000010232137,0.007096162,0.0002800972,0.0017541883,0.9898145],"study_design_scores_gemma":[0.0031131029,0.00022008095,0.00021961895,0.0012026461,0.00013727201,0.0009867445,0.0000056314625,0.0000050077383,0.00036274205,0.0008944633,0.99268353,0.00016914439],"about_ca_topic_score_codex":0.0000016187059,"about_ca_topic_score_gemma":0.000001361577,"teacher_disagreement_score":0.99092937,"about_ca_system_score_codex":0.00022866439,"about_ca_system_score_gemma":0.0002709108,"threshold_uncertainty_score":0.65052634},"labels":[],"label_agreement":null},{"id":"W2315848922","doi":"10.1017/s0007114512003807","title":"Attenuation of post-myocardial infarction depression in rats by<i>n</i>-3 fatty acids or probiotics starting after the onset of reperfusion","year":2012,"lang":"en","type":"article","venue":"British Journal Of Nutrition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lallemand (Canada); Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Proinflammatory cytokine; Lactobacillus helveticus; Endocrinology; TUNEL assay; Internal medicine; Medicine; Polyunsaturated fatty acid; Myocardial infarction; Lactobacillus; Biology; Inflammation; Biochemistry; Fatty acid","score_opus":0.01605285898233268,"score_gpt":0.2509216353313456,"score_spread":0.2348687763490129,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2315848922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980055,0.0008382103,0.00021949867,0.0003315508,0.00024625132,0.00027874805,0.000053290718,0.000006066269,0.000020878613],"genre_scores_gemma":[0.9983369,0.00085031526,0.00041434364,0.00024422666,0.000122030586,0.0000073608367,0.000007733483,0.0000111294175,0.000005964834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983502,0.00033840796,0.0006192822,0.00011262126,0.000392841,0.00018662646],"domain_scores_gemma":[0.9989354,0.00018695014,0.000548697,0.00009482243,0.00018344022,0.00005070756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062768225,0.0000857424,0.000193701,0.00012157917,0.000073443254,0.000026983424,0.000115118906,0.00009030697,0.0000318407],"category_scores_gemma":[0.00089730904,0.00007156941,0.00010057483,0.00029905635,0.000095485935,0.00062292063,0.000036899957,0.00024272197,0.0000010183571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018262772,0.0010467264,0.023134464,0.000110113455,0.0000058118017,0.000019582329,0.00046973815,0.000026281436,0.9543606,0.0000035147575,0.0010263228,0.01797056],"study_design_scores_gemma":[0.0021670812,0.0005048717,0.25897852,0.0013603001,0.000023255367,0.0009415823,0.00058355654,0.00008207268,0.7347432,0.0001882562,0.00029527885,0.00013206963],"about_ca_topic_score_codex":0.000029638159,"about_ca_topic_score_gemma":0.000023722918,"teacher_disagreement_score":0.23584406,"about_ca_system_score_codex":0.000042543885,"about_ca_system_score_gemma":0.000037328537,"threshold_uncertainty_score":0.2918516},"labels":[],"label_agreement":null},{"id":"W2316826747","doi":"10.1016/j.brainresbull.2016.03.012","title":"Physical activity and exercise attenuate neuroinflammation in neurological diseases","year":2016,"lang":"en","type":"review","venue":"Brain Research Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":127,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Neuroinflammation; Neuropathology; Neuroscience; Disease; Medicine; Major depressive disorder; Dementia; Psychology; Pathology; Amygdala","score_opus":0.10819324739443184,"score_gpt":0.3977319720956649,"score_spread":0.2895387247012331,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2316826747","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07338268,0.90927285,0.000004747559,0.011862338,0.00014397934,0.0038313703,0.00017980499,0.00023094713,0.0010912906],"genre_scores_gemma":[0.004063976,0.9940101,0.000004036657,0.00010223576,0.0001912139,0.0004039147,0.0000050675444,0.00006906558,0.0011503763],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9932984,0.0032721676,0.00030695082,0.001334648,0.0008610447,0.0009267546],"domain_scores_gemma":[0.99161315,0.0073644845,0.0001389899,0.00055393565,0.00003586486,0.00029359997],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007184609,0.0004319623,0.0010485342,0.00053109333,0.00021146573,0.00018670906,0.00068765273,0.00023314726,0.00017705784],"category_scores_gemma":[0.00688932,0.0002957614,0.00025407688,0.00069368543,0.0007929573,0.00009607354,0.00070704543,0.001190345,0.0011489128],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084431,0.0002664906,0.000006297236,0.0019303374,0.0000023038176,0.00028237162,0.000026513553,1.2205929e-7,0.00024279332,0.00041755574,0.0053054756,0.9914353],"study_design_scores_gemma":[0.0004898174,0.00016724195,0.0013144703,0.003101784,0.000011538518,0.000019752928,0.0000028538782,0.000027222342,0.00007169455,0.0007310452,0.9936818,0.00038078718],"about_ca_topic_score_codex":0.000015891326,"about_ca_topic_score_gemma":0.000002648668,"teacher_disagreement_score":0.99105453,"about_ca_system_score_codex":0.000038662514,"about_ca_system_score_gemma":0.00014037573,"threshold_uncertainty_score":0.99994946},"labels":[],"label_agreement":null},{"id":"W2320191747","doi":"10.6000/1927-5129.2016.12.21","title":"Diclofenac Sodium Inhibits Hepatic Tryptophan 2,3-Dioxygenase but Augments Brain Indoleamine 2,3-Dioxygenase Activities in Rats","year":2016,"lang":"en","type":"article","venue":"Journal of Basic & Applied Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Quinolinic acid; Indoleamine 2,3-dioxygenase; Kynurenine; Kynurenine pathway; Kynurenic acid; Diclofenac Sodium; Medicine; Internal medicine; Endocrinology; Diclofenac; Pharmacology; Inflammation; Tryptophan; Serotonin; Enzyme assay; Enzyme; Chemistry; Biochemistry; Glutamate receptor","score_opus":0.025344589014422526,"score_gpt":0.2616719141507521,"score_spread":0.23632732513632956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2320191747","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938285,0.0001512216,0.00028608728,0.0021441246,0.00048562424,0.0003515207,0.000018136914,0.00004166633,0.0026931397],"genre_scores_gemma":[0.99706936,0.000113273745,0.00025784216,0.001732987,0.00024762013,0.000020540485,3.3855665e-7,0.00002753586,0.00053050375],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99582446,0.00028200969,0.0009874939,0.0006577892,0.001392019,0.0008562188],"domain_scores_gemma":[0.99733,0.0011881723,0.00079595007,0.00030204497,0.000051338462,0.00033248425],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001571697,0.00038980646,0.0006028706,0.00084536395,0.00034066846,0.0001808055,0.0010787033,0.0001262874,0.00017369898],"category_scores_gemma":[0.0009078798,0.00025011858,0.00018659036,0.001292239,0.0010546405,0.0010351464,0.00017151945,0.00036875627,0.00006392007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024691803,0.000332617,0.00025015985,0.00002524243,0.000008051238,0.000098732926,0.0005449906,0.000026936128,0.98028547,0.0008930919,0.000891106,0.016396677],"study_design_scores_gemma":[0.002810999,0.00041454172,0.0023724122,0.00020148244,0.0000040336727,0.00009017195,0.0012051046,0.000045952536,0.98907316,0.002830784,0.00059193076,0.00035943795],"about_ca_topic_score_codex":0.000014395567,"about_ca_topic_score_gemma":0.00005230941,"teacher_disagreement_score":0.016037239,"about_ca_system_score_codex":0.0001716258,"about_ca_system_score_gemma":0.00047633893,"threshold_uncertainty_score":0.9999951},"labels":[],"label_agreement":null},{"id":"W2320665292","doi":"10.2174/138955711795906888","title":"Antidepressants and Neuroinflammation: Can Antidepressants Calm Glial Rage Down?","year":2011,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Neuroinflammation; Astrogliosis; Microglia; Neuroscience; Antidepressant; Medicine; Gliosis; Astrocyte; Inflammation; Pharmacology; Immunology; Biology; Central nervous system; Hippocampus","score_opus":0.08061159292120237,"score_gpt":0.3306726767791806,"score_spread":0.2500610838579782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2320665292","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001348262,0.98590434,0.000004307057,0.000053000585,0.00047603637,0.001312979,0.0001357897,0.00007933914,0.010685935],"genre_scores_gemma":[0.000594696,0.9969854,0.000051135677,0.00026691842,0.00052099396,0.00019312098,0.00004508419,0.00009443765,0.001248219],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99455416,0.00058329024,0.0018597963,0.0016095543,0.00057102914,0.00082215056],"domain_scores_gemma":[0.99702483,0.0005115814,0.000961001,0.00109504,0.000023388811,0.00038414597],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008442438,0.0010476927,0.0031623202,0.00018085334,0.00015170554,0.00007364369,0.0012180944,0.0005809089,0.0007034387],"category_scores_gemma":[0.0026217008,0.0008280916,0.00042980682,0.00062348397,0.0006309822,0.00015744816,0.00037546988,0.0013959791,0.00009827278],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017650149,0.000098255376,0.000035559122,0.02801817,0.0000145376935,0.0005452227,0.00018509658,4.246006e-8,0.0016200283,0.000009435557,0.0022468423,0.96720916],"study_design_scores_gemma":[0.0007637455,0.00003237545,0.00004677722,0.019562753,0.00020690341,0.0006573759,0.000026082278,0.0000044286867,0.003133498,0.000035439723,0.9747335,0.0007971676],"about_ca_topic_score_codex":0.000039352213,"about_ca_topic_score_gemma":0.000018140521,"teacher_disagreement_score":0.9724866,"about_ca_system_score_codex":0.00007339602,"about_ca_system_score_gemma":0.000254123,"threshold_uncertainty_score":0.999417},"labels":[],"label_agreement":null},{"id":"W2322941916","doi":"10.2174/156802612805219969","title":"Recent Developments in the Regulation of Monoamine Oxidase Form and Function: Is the Current Model Restricting Our Understanding of the Breadth of Contribution of Monoamine Oxidase to Brain [dys]Function?","year":2012,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Monoamine neurotransmitter; Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase A; Dopamine; Serotonin; Chemistry; Neuroscience; Biochemistry; Biology; Enzyme; Receptor","score_opus":0.13512804513257068,"score_gpt":0.35522062895266776,"score_spread":0.22009258382009708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2322941916","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.081925765,0.90854967,0.0038477327,0.0016087028,0.0012275183,0.0023588056,0.00012659817,0.00001508233,0.00034011918],"genre_scores_gemma":[0.62565637,0.37396273,0.000022182036,0.0000573249,0.00014708667,0.00005990005,0.000042103537,0.000016499884,0.000035796314],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975156,0.00017870856,0.0010866998,0.00032641017,0.00063928316,0.0002532757],"domain_scores_gemma":[0.998085,0.0003847982,0.0009478658,0.0004231247,0.0001029996,0.000056184494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009391331,0.00027439886,0.0006482535,0.00012193165,0.00008245316,0.000008101423,0.0004100413,0.00013501644,0.0000070161036],"category_scores_gemma":[0.0010812538,0.00016021673,0.00013010445,0.0009152217,0.00015829208,0.00007638754,0.00015880784,0.0005820621,1.6576215e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011017233,0.00040716474,0.00075227075,0.010236509,0.000027920662,4.025613e-7,0.0013887985,0.000050813785,0.002672583,0.0016245581,0.00033981513,0.982389],"study_design_scores_gemma":[0.013550936,0.0008217425,0.02612637,0.12292069,0.0027793127,0.00012435064,0.011299312,0.0072782706,0.091262355,0.01568886,0.7052061,0.0029416992],"about_ca_topic_score_codex":0.000005975874,"about_ca_topic_score_gemma":0.000006803233,"teacher_disagreement_score":0.9794473,"about_ca_system_score_codex":0.000250807,"about_ca_system_score_gemma":0.00023525183,"threshold_uncertainty_score":0.65334487},"labels":[],"label_agreement":null},{"id":"W2328376535","doi":"10.1097/psy.0000000000000078","title":"Family Chaos and Adolescent Inflammatory Profiles","year":2014,"lang":"en","type":"article","venue":"Psychosomatic Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Proinflammatory cytokine; Socioeconomic status; Inflammation; Systemic inflammation; Cytokine; Medicine; Immunology; Interleukin 6; Population; Environmental health","score_opus":0.02686903839971627,"score_gpt":0.26980903487886243,"score_spread":0.24293999647914616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2328376535","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96928704,0.00036699482,0.0009904685,0.005877829,0.0005106233,0.00048980117,0.0000011709948,0.00017340975,0.022302663],"genre_scores_gemma":[0.9898525,0.00017841911,0.0001544705,0.009070458,0.00027161493,0.00003275863,0.0000010403088,0.00001914206,0.00041961097],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99875265,0.00010873503,0.00026820935,0.00032470818,0.00030920756,0.00023647513],"domain_scores_gemma":[0.99924785,0.00018567155,0.00009272398,0.00030283164,0.000013746179,0.0001571893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020551056,0.00015758433,0.00021279084,0.00009901476,0.00008504455,0.000013868549,0.00018070091,0.00004618335,0.00012002653],"category_scores_gemma":[0.0006573996,0.000112616974,0.000021617687,0.00014769458,0.0003082922,0.0000652856,0.00002954099,0.00011627039,0.00012474645],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060932154,0.00023400682,0.017242558,0.0011378938,0.000014008759,0.000010255441,0.0020593044,0.0000016501696,0.81043017,0.014330386,0.09702129,0.057457533],"study_design_scores_gemma":[0.012515346,0.0011255696,0.6954145,0.0033855047,0.000058576952,0.0001649041,0.0015734812,0.008831325,0.047103733,0.035549033,0.19295219,0.0013258624],"about_ca_topic_score_codex":0.0000024508615,"about_ca_topic_score_gemma":7.3880057e-7,"teacher_disagreement_score":0.76332647,"about_ca_system_score_codex":0.000007948368,"about_ca_system_score_gemma":0.000009612009,"threshold_uncertainty_score":0.45923868},"labels":[],"label_agreement":null},{"id":"W2328568124","doi":"10.1158/1538-7445.am10-1489","title":"Abstract 1489: Basal cell carcinomas express functional indoleamine 2,3-dioxygenase (IDO) which may confer immunoprotection","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Basal cell carcinoma; Indoleamine 2,3-dioxygenase; Biology; Immune system; Cancer research; Hair follicle; Kynurenine; Keratinocyte; Carcinogenesis; FOXP3; Immunology; Downregulation and upregulation; Cancer; Cell biology; Medicine; Pathology; Cell culture; Basal cell; Gene","score_opus":0.08472240354582905,"score_gpt":0.3436644546561708,"score_spread":0.25894205111034174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2328568124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98558336,0.00015582336,0.00005245139,0.0008791044,0.0010509021,0.0006146373,0.000060378352,0.00009312571,0.011510187],"genre_scores_gemma":[0.99352986,0.00007328752,0.000026407235,0.00022714442,0.0006274151,0.00039360026,0.000010877268,0.000051753723,0.0050596735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968947,0.00020335872,0.00025940718,0.0007570275,0.0010825329,0.0008029763],"domain_scores_gemma":[0.9983996,0.00033714177,0.000067746696,0.0005792551,0.0003759009,0.00024033722],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00072530843,0.00021535979,0.00017989893,0.00032092573,0.00054282794,0.00019868213,0.0005238553,0.00021386478,0.0054234318],"category_scores_gemma":[0.00056156114,0.00019969966,0.00007892465,0.000815048,0.0003945901,0.00031530598,0.00018487913,0.0018827571,0.0005379472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003091287,0.00016451976,0.0002396286,0.00007017008,0.0000043113187,0.000018225863,0.00015165382,0.000044706798,0.9906466,0.00027727132,0.005986232,0.0020875637],"study_design_scores_gemma":[0.0011008274,0.00008020773,0.048842467,0.00001764318,0.0000010740713,0.0000063430416,0.0001329423,0.00007357928,0.927527,0.0002167394,0.021781664,0.00021952474],"about_ca_topic_score_codex":0.0010061995,"about_ca_topic_score_gemma":0.0004829052,"teacher_disagreement_score":0.063119605,"about_ca_system_score_codex":0.00011482711,"about_ca_system_score_gemma":0.00054634747,"threshold_uncertainty_score":0.9954857},"labels":[],"label_agreement":null},{"id":"W2331353920","doi":"10.1021/np300345j","title":"Halicloic Acids A and B Isolated from the Marine Sponge <i>Haliclona</i> sp. Collected in the Philippines Inhibit Indoleamine 2,3-Dioxygenase","year":2012,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Decarboxylation; Sponge; Stereochemistry; Indoleamine 2,3-dioxygenase; Chemistry; Carbon skeleton; Biology; Amino acid; Biochemistry; Botany; Tryptophan","score_opus":0.020090573607391162,"score_gpt":0.23882499066184107,"score_spread":0.2187344170544499,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2331353920","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.978186,0.0045949197,8.090857e-7,0.016149133,0.000580308,0.0003494658,0.000010752065,0.000016626534,0.00011194366],"genre_scores_gemma":[0.99508566,0.00024252346,0.00006267797,0.0035405385,0.0008696849,0.0000032209075,0.000003476714,0.000017331888,0.00017487306],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980315,0.00043806634,0.00045240478,0.00023805085,0.00045600106,0.0003839677],"domain_scores_gemma":[0.99871856,0.00046660146,0.0003233444,0.00029052407,0.000121992045,0.00007895281],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007211635,0.00021612807,0.0002731471,0.00013135589,0.00017943687,0.00010282018,0.00050915324,0.00007314841,0.000026870623],"category_scores_gemma":[0.00271143,0.00010794962,0.000068773195,0.0013124129,0.00015445486,0.0005428961,0.00013849663,0.00079429656,0.000007618625],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088359823,0.00039274123,0.004852706,0.000024698258,0.000027232818,0.00011756641,0.003847577,0.0000029078756,0.97701836,0.00012406826,0.007970376,0.0047381916],"study_design_scores_gemma":[0.0042876313,0.00037886956,0.5404883,0.00011885293,0.000034492026,0.002027732,0.00081294647,0.00012175755,0.4216744,0.00094426895,0.028662583,0.00044816695],"about_ca_topic_score_codex":0.00005939973,"about_ca_topic_score_gemma":0.00006567226,"teacher_disagreement_score":0.5553439,"about_ca_system_score_codex":0.00003396362,"about_ca_system_score_gemma":0.00006235822,"threshold_uncertainty_score":0.44020578},"labels":[],"label_agreement":null},{"id":"W2332863458","doi":"10.1177/0706743716635535","title":"Posttraumatic Stress Disorder: Does the Gut Microbiome Hold the Key?","year":2016,"lang":"en","type":"review","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":125,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Immune system; Gut flora; Endocrine system; Microbiome; Gut–brain axis; Neuroscience; Biology; Psychology; Immunology; Bioinformatics; Endocrinology; Hormone","score_opus":0.030885431921490358,"score_gpt":0.279712317923191,"score_spread":0.24882688600170066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2332863458","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029211646,0.9533825,0.000004756342,0.03904036,0.0052250065,0.0006555199,0.00038265882,0.0000108104105,0.0010062783],"genre_scores_gemma":[0.001500461,0.9928663,0.00002701999,0.0030455226,0.001198075,0.000015588059,0.0000024227006,0.000090817244,0.0012538395],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99684906,0.00088194344,0.0009137886,0.00029262103,0.00038201854,0.0006805424],"domain_scores_gemma":[0.99665326,0.0007422612,0.0011782147,0.0010147685,0.000059105885,0.00035238804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007411169,0.00048368142,0.0007848448,0.0002808778,0.0012766715,0.00042562818,0.003913733,0.00020514365,0.0003811193],"category_scores_gemma":[0.0002708704,0.0001491554,0.0009018282,0.0005879492,0.0010174824,0.00012966816,0.000059294543,0.0011880642,0.00018656904],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002340137,0.00015155801,0.00013920863,0.0045246235,0.0005276321,0.00009785134,0.00250646,0.000007330814,0.000028087572,0.04264373,0.098814525,0.8505356],"study_design_scores_gemma":[0.00020598213,0.000055469845,0.000050524926,0.005679539,0.00022477262,0.0007136239,0.00034418819,4.9851303e-7,0.000003864894,0.005458991,0.9869811,0.0002814736],"about_ca_topic_score_codex":0.0017000029,"about_ca_topic_score_gemma":0.18482183,"teacher_disagreement_score":0.88816655,"about_ca_system_score_codex":0.00013263752,"about_ca_system_score_gemma":0.0041807727,"threshold_uncertainty_score":0.9819254},"labels":[],"label_agreement":null},{"id":"W2338925098","doi":"10.1503/jpn.150226","title":"Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individuals","year":2016,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health","keywords":"Quinolinic acid; Kynurenine pathway; Kynurenic acid; Kynurenine; Indoleamine 2,3-dioxygenase; Prefrontal cortex; Endocrinology; Internal medicine; Biology; Medicine; Tryptophan; Biochemistry; Glutamate receptor; Neuroscience; Receptor; Amino acid; Cognition","score_opus":0.019408473844605534,"score_gpt":0.25873041948405245,"score_spread":0.23932194563944692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2338925098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99626297,0.00057016005,0.0001404844,0.0021061616,0.0006627592,0.00011862848,0.000017635542,0.00000494778,0.00011626407],"genre_scores_gemma":[0.99838716,0.00052305585,0.00028733566,0.0006917666,0.000073608106,0.000001967926,4.4283716e-8,0.000006328233,0.000028717066],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998439,0.00024383226,0.00041607927,0.0002675408,0.00043325045,0.0002002629],"domain_scores_gemma":[0.99906325,0.00023627201,0.00041881276,0.00017033814,0.000022766286,0.0000885443],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004805024,0.00012770011,0.00021787548,0.00015878132,0.00010809617,0.00004225516,0.0004496955,0.000045139255,0.000007974996],"category_scores_gemma":[0.0004990157,0.00006287655,0.000053171647,0.00031606667,0.00039380605,0.0004726609,0.00007361291,0.0001770193,2.773031e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008447582,0.00014920218,0.0046955915,0.000010583546,6.020337e-7,0.000007845949,0.00026231466,0.0000014539349,0.99245626,0.0007290123,0.00010500073,0.001497683],"study_design_scores_gemma":[0.0013000177,0.0002859338,0.51866543,0.0001098785,0.0000061058363,0.00026135618,0.00011148011,0.000008073198,0.4766718,0.0018399899,0.00065307645,0.000086891894],"about_ca_topic_score_codex":0.0000013046014,"about_ca_topic_score_gemma":0.0000034179764,"teacher_disagreement_score":0.51578444,"about_ca_system_score_codex":0.0000031641976,"about_ca_system_score_gemma":0.00007639097,"threshold_uncertainty_score":0.25640312},"labels":[],"label_agreement":null},{"id":"W2339925206","doi":"10.1503/jpn.150195","title":"Evidence of activation of the Toll-like receptor-4 proinflammatory pathway in patients with schizophrenia","year":2016,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Proinflammatory cytokine; Innate immune system; Schizophrenia (object-oriented programming); TLR4; Toll-like receptor; Pattern recognition receptor; Antipsychotic; Psychosis; Immunology; Medicine; Biology; Immune system; Inflammation; Psychiatry","score_opus":0.017547850979077507,"score_gpt":0.23166540730476937,"score_spread":0.21411755632569185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2339925206","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978939,0.00004868709,0.00010259444,0.0011398437,0.0006325861,0.00015107979,0.0000036114875,0.0000032462633,0.000024395758],"genre_scores_gemma":[0.99945545,0.00005882883,0.00021203826,0.00021362118,0.000023076105,0.0000010245055,1.0028318e-8,0.0000058421792,0.0000301078],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985848,0.00014860074,0.0004085054,0.00019911476,0.0005144202,0.00014453773],"domain_scores_gemma":[0.99881905,0.00016425707,0.00070018397,0.00019111199,0.000070255934,0.000055130782],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027266558,0.000099438206,0.00015980579,0.00012901254,0.000060460196,0.000013201223,0.00041815752,0.0000326676,0.000006367689],"category_scores_gemma":[0.0006202143,0.000048434547,0.000051695413,0.000495175,0.00041453046,0.0007037168,0.00005368624,0.00013898381,4.2825582e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008267034,0.00020438149,0.2503068,0.000045162873,7.47395e-7,5.4932167e-7,0.00009421441,0.000017057197,0.7455877,0.0008359706,0.00006124148,0.002019454],"study_design_scores_gemma":[0.0015435806,0.0006860315,0.6552703,0.0011357622,0.0000023378282,0.000009552145,0.00002757048,0.0000061726164,0.3406664,0.00047098033,0.00009627806,0.00008505784],"about_ca_topic_score_codex":6.836768e-7,"about_ca_topic_score_gemma":0.0000032694927,"teacher_disagreement_score":0.4049635,"about_ca_system_score_codex":0.000012116691,"about_ca_system_score_gemma":0.00023838674,"threshold_uncertainty_score":0.19751036},"labels":[],"label_agreement":null},{"id":"W2340213393","doi":"10.1016/j.jns.2015.08.439","title":"Correction of vitamin d status improves lymphocyte susceptibility to oxidative cell death in mild cognitive impairtment patients","year":2015,"lang":"en","type":"article","venue":"Journal of the Neurological Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Comisión Nacional de Investigación Científica y Tecnológica","keywords":"Dementia; Biomarker; Medicine; Lymphocyte; Cognitive decline; Programmed cell death; Montreal Cognitive Assessment; Internal medicine; Vitamin E; Disease; Immunology; Oncology; Biology; Apoptosis; Biochemistry; Antioxidant","score_opus":0.0404660664451124,"score_gpt":0.28620301210323623,"score_spread":0.24573694565812382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2340213393","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99776685,0.000015228713,0.000016215872,0.0002854862,0.0009850609,0.00027614925,0.000007353611,0.0000055922833,0.0006420693],"genre_scores_gemma":[0.99870026,0.000016397971,0.00007250686,0.0011625362,0.0000196845,0.0000024354358,7.806603e-8,0.0000024026158,0.000023676525],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9978475,0.00053713017,0.00038756485,0.0002734351,0.00065665523,0.0002977184],"domain_scores_gemma":[0.99856126,0.00063503516,0.00040971366,0.00008806172,0.00013027767,0.00017563242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070832594,0.00011519094,0.00020308311,0.00011360995,0.00009446067,0.00003337625,0.00049841724,0.000044706896,0.000010794843],"category_scores_gemma":[0.0038704728,0.000060001403,0.0000967853,0.0006950513,0.00040456775,0.00022249171,0.00017745669,0.00019537845,0.0000040518453],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025746233,0.002606306,0.8185167,0.000011283925,0.000004618608,0.000017712637,0.0025312104,0.0026383689,0.15631372,0.00003827171,0.00072825456,0.014018944],"study_design_scores_gemma":[0.0013871411,0.0062366067,0.7908624,0.00002062993,0.0000055543665,0.0000051979464,0.00045783276,0.0005809961,0.19973975,0.00054728985,0.00006874877,0.0000878474],"about_ca_topic_score_codex":0.00004501444,"about_ca_topic_score_gemma":0.000040258597,"teacher_disagreement_score":0.043426033,"about_ca_system_score_codex":0.00007989953,"about_ca_system_score_gemma":0.00017937331,"threshold_uncertainty_score":0.46335968},"labels":[],"label_agreement":null},{"id":"W2341986749","doi":"10.1097/qai.0000000000000859","title":"Influence of Hepatitis C Virus Sustained Virological Response on Immunosuppressive Tryptophan Catabolism in ART-Treated HIV/HCV Coinfected Patients","year":2015,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Université du Québec à Montréal","funders":"McGill University Health Centre; Canadian Institutes of Health Research; Canadian Foundation for AIDS Research","keywords":"Coinfection; Hepatitis C virus; Immunology; Liver disease; Medicine; Hepatitis C; Internal medicine; Catabolism; Hepacivirus; Gastroenterology; Human immunodeficiency virus (HIV); Virus; Metabolism","score_opus":0.015995939411043887,"score_gpt":0.25337228849781257,"score_spread":0.2373763490867687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2341986749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99826247,0.00041892807,0.000015060126,0.00020522198,0.0003174922,0.00040820835,0.000079792306,0.000064609994,0.00022822473],"genre_scores_gemma":[0.99923474,0.00028276892,0.00005511558,0.00016850462,0.000014226699,0.000013845233,0.000010892759,0.00004401195,0.00017587187],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99483526,0.001272534,0.0016066096,0.00046847542,0.0011069332,0.000710183],"domain_scores_gemma":[0.9961999,0.0012505754,0.001228252,0.00055588037,0.0005484957,0.00021690126],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010984737,0.00042458635,0.0009445957,0.0012078714,0.00013080779,0.00006678873,0.0010171013,0.00023024534,0.00004854328],"category_scores_gemma":[0.011644368,0.000344405,0.00026097047,0.0018353454,0.0006215677,0.0007427182,0.00019605567,0.00031790056,0.00011913544],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013608947,0.0039129173,0.08113341,0.000068532885,0.00005200423,0.001528906,0.0041186344,0.00784565,0.8849201,0.00050402625,0.0010736325,0.001233245],"study_design_scores_gemma":[0.0064254734,0.004092182,0.8053063,0.00023717002,0.000023992348,0.0001802085,0.00039394203,0.00011589683,0.18215287,0.0004851003,0.00018560077,0.00040125742],"about_ca_topic_score_codex":0.00012548994,"about_ca_topic_score_gemma":0.000005766829,"teacher_disagreement_score":0.7241729,"about_ca_system_score_codex":0.00021347622,"about_ca_system_score_gemma":0.00031917228,"threshold_uncertainty_score":0.9999008},"labels":[],"label_agreement":null},{"id":"W2343003799","doi":"10.1016/j.pnpbp.2016.04.012","title":"Tryptophan via serotonin/kynurenine pathways abnormalities in a large cohort of aggressive inmates: markers for aggression","year":2016,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Université du Québec à Trois-Rivières; Université du Québec à Montréal; Institut national de psychiatrie légale Philippe-Pinel; Université de Sherbrooke; McGill University Health Centre","funders":"","keywords":"Conduct disorder; Kynurenine; Impulsivity; Aggression; Serotonin; Psychology; Psychopathology; Psychiatry; Attention deficit hyperactivity disorder; Poison control; Internal medicine; Fenfluramine; Confounding; Clinical psychology; Medicine; Tryptophan; Chemistry","score_opus":0.022114107343358797,"score_gpt":0.3025684027702615,"score_spread":0.2804542954269027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2343003799","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991443,0.0033199976,0.000075314325,0.0015926446,0.0014403706,0.0017321944,0.00015859221,0.00009453646,0.00014338938],"genre_scores_gemma":[0.9934616,0.0030082655,0.000365558,0.0022103162,0.00011461081,0.0007855168,0.0000079975,0.000027615924,0.00001849276],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.996615,0.00056014356,0.00077923265,0.0010223757,0.0001837712,0.0008394925],"domain_scores_gemma":[0.9978636,0.0010297325,0.000671773,0.00023622325,0.000041832584,0.00015684628],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005151462,0.00040819283,0.0006030482,0.0003325728,0.0001347928,0.000016620588,0.00048845133,0.00041359238,0.00018208598],"category_scores_gemma":[0.00046600163,0.0002553214,0.00014566054,0.00047072035,0.00096481456,0.00017337524,0.00016846856,0.00036633437,0.000005695588],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005817653,0.001049291,0.94749206,0.00013703214,0.000017084058,0.000057678244,0.0001262424,7.6305463e-7,0.025252797,0.0015096284,0.0003346328,0.01820514],"study_design_scores_gemma":[0.01617534,0.0016595656,0.9593632,0.0005939,0.00001630691,0.000072191724,0.00014168026,0.00014648413,0.010075165,0.01040154,0.00079179794,0.00056282384],"about_ca_topic_score_codex":0.0000017181789,"about_ca_topic_score_gemma":0.000011439733,"teacher_disagreement_score":0.017642317,"about_ca_system_score_codex":0.00002292533,"about_ca_system_score_gemma":0.000053761265,"threshold_uncertainty_score":0.9999899},"labels":[],"label_agreement":null},{"id":"W2343019844","doi":"10.2174/1566524016666160429121737","title":"Repurposing of Anti-Diabetic Agents for the Treatment of Cognitive Impairment and Mood Disorders","year":2016,"lang":"en","type":"review","venue":"Current Molecular Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dementia; Mood; Cognition; Mood disorders; Disease; Psychology; Bioinformatics; Depression (economics); Medicine; Neuroscience; Clinical psychology; Psychiatry; Internal medicine; Anxiety; Biology","score_opus":0.05730538215770534,"score_gpt":0.3646784472039899,"score_spread":0.3073730650462846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2343019844","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011443046,0.99383813,0.001001348,0.000096280484,0.00050042226,0.0031820051,0.00014732209,0.000013748488,0.00007643272],"genre_scores_gemma":[0.008950625,0.9906068,0.000006599612,0.000022457321,0.000057091467,0.00026520656,0.00002785931,0.000039986873,0.000023378187],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981362,0.00017912858,0.00058994215,0.0005000585,0.0003146163,0.0002800157],"domain_scores_gemma":[0.99774826,0.0012343595,0.00054716936,0.00034129948,0.000042993262,0.00008589582],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013395229,0.0003882583,0.0011964055,0.00016707456,0.00007059283,0.0000060323578,0.00022246818,0.00007865828,0.000026822734],"category_scores_gemma":[0.00048967416,0.00019107365,0.00036576783,0.0002408236,0.0006503109,0.000022920562,0.00004647315,0.00007833054,0.0000017952699],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014023945,0.0003783119,0.0000051793313,0.0045918105,0.00010196541,0.0000014518938,0.00033150727,1.2531694e-7,0.00032237882,0.00016067362,0.00004322737,0.9940494],"study_design_scores_gemma":[0.0057021966,0.0029796755,0.00007399226,0.05366079,0.0022737568,0.000013259079,0.00014647098,0.00002508264,0.003886666,0.000339508,0.9304475,0.00045109543],"about_ca_topic_score_codex":0.0000030558047,"about_ca_topic_score_gemma":7.7206346e-7,"teacher_disagreement_score":0.9935982,"about_ca_system_score_codex":0.00004018734,"about_ca_system_score_gemma":0.00008112784,"threshold_uncertainty_score":0.77917576},"labels":[],"label_agreement":null},{"id":"W2344254260","doi":"10.1016/j.physbeh.2016.04.052","title":"Involvement of D1 and D2 dopamine receptors in the antidepressant-like effects of selegiline in maternal separation model of mouse","year":2016,"lang":"en","type":"article","venue":"Physiology & Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Selegiline; Behavioural despair test; Psychology; Antidepressant; Dopamine; Open field; Sulpiride; Dopamine receptor D2; Dopaminergic; Monoamine oxidase B; Internal medicine; Endocrinology; Receptor antagonist; Pharmacology; Antagonist; Neuroscience; Receptor; Medicine; Chemistry; Monoamine oxidase; Parkinson's disease; Psychiatry; Hippocampus","score_opus":0.024079197569862622,"score_gpt":0.28252943851250517,"score_spread":0.2584502409426426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2344254260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99952734,0.000021856657,0.000017838769,0.000032121883,0.000053267773,0.0003171741,0.000017674349,0.000005210345,0.000007541633],"genre_scores_gemma":[0.9996917,0.00010661749,0.000047450452,0.00005491838,0.0000052476207,0.000044877517,0.0000019233069,0.0000062991617,0.000040940813],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991432,0.00014872258,0.00026856404,0.00020026193,0.00010860803,0.00013065936],"domain_scores_gemma":[0.9994842,0.00016987832,0.00014175322,0.00017232895,0.00001765895,0.000014187526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010005117,0.00009064007,0.00021258519,0.00009031939,0.00001122723,0.0000015262428,0.00016298288,0.000047552054,0.0000068747318],"category_scores_gemma":[0.000048326856,0.000054513537,0.00002903413,0.00008942316,0.00022688098,0.00008083812,0.00005175074,0.00005486329,7.0972635e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009583573,0.00035445025,0.036654945,0.00004483608,0.0000011731491,0.0000010441892,0.00023873232,0.000063496744,0.96158004,0.00015883098,0.0000114320155,0.00079519366],"study_design_scores_gemma":[0.0008306955,0.00015065615,0.23216636,0.000033814445,0.0000054692964,4.8482974e-7,0.000024594268,0.000225385,0.7664444,0.000072927105,0.0000019273525,0.000043295757],"about_ca_topic_score_codex":0.00007238868,"about_ca_topic_score_gemma":0.000050508883,"teacher_disagreement_score":0.19551142,"about_ca_system_score_codex":0.000007698095,"about_ca_system_score_gemma":0.000013167233,"threshold_uncertainty_score":0.22229975},"labels":[],"label_agreement":null},{"id":"W2344505457","doi":"10.1016/j.neuropharm.2016.04.021","title":"Ketamine modulates hippocampal neurogenesis and pro-inflammatory cytokines but not stressor induced neurochemical changes","year":2016,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":94,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Canadian Institutes of Health Research","keywords":"Neurochemical; Ketamine; Corticosterone; Monoamine neurotransmitter; NMDA receptor; Antidepressant; Pharmacology; Proinflammatory cytokine; Medicine; Internal medicine; Psychology; Endocrinology; Hippocampus; Neuroscience; Receptor; Hormone; Serotonin; Inflammation","score_opus":0.03661496499477499,"score_gpt":0.2742052587565025,"score_spread":0.2375902937617275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2344505457","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99209756,0.00004929302,0.0000056256276,0.0060992,0.0008111681,0.0004734564,0.00004581609,0.00031262045,0.00010524598],"genre_scores_gemma":[0.99139374,0.0004044458,0.000013511015,0.007348795,0.00033620792,0.00009567657,0.0000010145537,0.00007649321,0.00033009992],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972879,0.00040628412,0.00031224737,0.001028099,0.0002823943,0.0006830528],"domain_scores_gemma":[0.99818754,0.001021744,0.00015618764,0.00030904176,0.000049897037,0.00027559494],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000772111,0.00039102283,0.00035066446,0.00020545209,0.00017020374,0.00004147859,0.00045230158,0.00015504107,0.00022882332],"category_scores_gemma":[0.0008423321,0.0002919853,0.00007373498,0.0002444067,0.0004268885,0.00017088653,0.00032780078,0.00024640586,0.000090162124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003052416,0.00009118897,0.00086029863,0.00003678786,0.000007809139,0.0002950633,0.000035726214,0.0000013705913,0.9804935,0.00007681377,0.00032130853,0.017474895],"study_design_scores_gemma":[0.002001281,0.0003064364,0.019708525,0.000009218277,0.000022997681,0.0001472749,0.000005938577,0.00011848237,0.97456074,0.000055126187,0.0027561581,0.000307815],"about_ca_topic_score_codex":0.0000031388881,"about_ca_topic_score_gemma":0.0000041304775,"teacher_disagreement_score":0.018848227,"about_ca_system_score_codex":0.00001920922,"about_ca_system_score_gemma":0.000044175802,"threshold_uncertainty_score":0.9999532},"labels":[],"label_agreement":null},{"id":"W2345604850","doi":"10.1038/nm.4106","title":"Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor","year":2016,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1526,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Aryl hydrocarbon receptor; Inflammation; Experimental autoimmune encephalomyelitis; Microglia; Kynurenine; Immunology; Biology; Astrocyte; Central nervous system; Multiple sclerosis; Cytokine; Chemistry; Tryptophan; Biochemistry; Endocrinology; Transcription factor","score_opus":0.00802789140291715,"score_gpt":0.22697735719203926,"score_spread":0.2189494657891221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2345604850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950971,0.00088384375,0.00030479635,0.0026927327,0.0005827664,0.00024576808,0.000010401041,0.0000441647,0.00013844024],"genre_scores_gemma":[0.9993102,0.00016223874,0.000030051608,0.00013256588,0.0002752587,0.0000031898276,0.0000016258101,0.000012703162,0.00007216153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999019,0.00010634525,0.00018255856,0.00027797636,0.00019783927,0.00021623216],"domain_scores_gemma":[0.9993282,0.00022960469,0.00013904613,0.00019007176,0.000033757267,0.00007934272],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013329397,0.00015564634,0.00023971776,0.00007874776,0.00007292724,0.000010532197,0.00014076686,0.0001395211,0.000016309446],"category_scores_gemma":[0.0003837567,0.00007704473,0.000026031483,0.00019149028,0.00034685974,0.00012333744,0.00005818541,0.0002459717,0.0000020294117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024609396,0.000009951766,0.00013206269,0.00005361473,0.000009987742,0.0000015779246,0.00036605223,6.046485e-7,0.9719532,0.000621737,0.00008219882,0.026522897],"study_design_scores_gemma":[0.0011438577,0.00018467304,0.019390702,0.00019055704,0.000024743207,0.000030476709,0.00006575811,0.00026785562,0.97755176,0.00010513662,0.0009519658,0.00009252388],"about_ca_topic_score_codex":0.000024748453,"about_ca_topic_score_gemma":0.000017136612,"teacher_disagreement_score":0.026430374,"about_ca_system_score_codex":0.00002644772,"about_ca_system_score_gemma":0.000017729835,"threshold_uncertainty_score":0.31417927},"labels":[],"label_agreement":null},{"id":"W2368013400","doi":"10.1016/j.eurpsy.2016.01.072","title":"Peripheral sub-inflammation is associated with antidepressant consumption in schizophrenia. Results from the multi-center FACE-SZ dataset","year":2016,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Depression (economics); Confounding; Internal medicine; Medicine; Antidepressant; Schizophrenia (object-oriented programming); Comorbidity; Psychiatry; Psychology","score_opus":0.032327932789171,"score_gpt":0.25632326993504884,"score_spread":0.22399533714587783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2368013400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890153,0.00008207388,0.00024196645,0.0036161607,0.00047002255,0.0002992618,0.0057882722,0.00010881466,0.00037813527],"genre_scores_gemma":[0.99732524,0.000074493735,0.00019477536,0.001638974,0.00014371697,0.0000044066205,0.00045923635,0.00004192694,0.000117242635],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99770564,0.0007051294,0.0003767194,0.0006227642,0.00028070435,0.00030902005],"domain_scores_gemma":[0.9988861,0.00021651639,0.00023296832,0.00058375514,0.000014939603,0.00006571501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031404782,0.00021733977,0.00014128949,0.000055002653,0.00016379869,0.00010539581,0.00046600724,0.000044513166,0.000073591975],"category_scores_gemma":[0.00038120477,0.00012222459,0.00004565333,0.0001798757,0.00018067702,0.00032135114,0.000097266355,0.00020252645,0.00046910986],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0078178225,0.0023682655,0.43516958,0.00004045598,0.00011585195,0.00023733209,0.008180854,0.00010245989,0.28582197,0.00059959764,0.23448308,0.025062738],"study_design_scores_gemma":[0.029325362,0.00011179685,0.94821686,0.0008236255,0.000017299231,0.000011538172,0.00025231775,0.0003785146,0.011314854,0.00009553671,0.00885152,0.0006007729],"about_ca_topic_score_codex":0.000023749937,"about_ca_topic_score_gemma":0.0005158198,"teacher_disagreement_score":0.5130473,"about_ca_system_score_codex":0.00003135909,"about_ca_system_score_gemma":0.000030481426,"threshold_uncertainty_score":0.6029615},"labels":[],"label_agreement":null},{"id":"W2385771159","doi":"10.1016/j.eurpsy.2016.01.635","title":"Inflammatory and metabolic biomarkers of psychopathological dimensions of schizophrenia","year":2016,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Internal medicine; Insulin resistance; Biomarker; Psychopathology; Medicine; Homocysteine; Body mass index; Comorbidity; Positive and Negative Syndrome Scale; Psychosis; Depression (economics); Psychiatry; Psychology; Obesity; Biology","score_opus":0.01472721774408754,"score_gpt":0.2387678370224735,"score_spread":0.22404061927838598,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2385771159","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99025726,0.0010921257,0.00007605285,0.0005402266,0.00050849485,0.000108759115,0.000023524712,0.00006117114,0.007332389],"genre_scores_gemma":[0.99797326,0.00027095742,0.0013109993,0.00026740826,0.0000559355,0.0000013174675,2.5259337e-7,0.000023454106,0.00009638691],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986334,0.0003450159,0.00033653365,0.00034104948,0.00016298592,0.00018102508],"domain_scores_gemma":[0.9992522,0.000109437206,0.00017851275,0.00034856884,0.000018141476,0.00009311361],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023283155,0.00013797979,0.00018774452,0.0001333799,0.000054133954,0.000006394592,0.00024389786,0.000033897886,0.00006154927],"category_scores_gemma":[0.00023843319,0.00007801286,0.00008813382,0.0002123923,0.00049002905,0.000085352774,0.00010675759,0.00006912238,0.000056082314],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020898404,0.00014631063,0.015014591,0.000026682214,0.000013008757,0.0000077797995,0.00013487077,2.4541694e-7,0.94842464,0.019592214,0.0015147361,0.014915937],"study_design_scores_gemma":[0.006013962,0.00040991628,0.81297123,0.0004680059,0.000043641998,0.00008867071,0.00027618857,0.00000576355,0.15928407,0.007774958,0.012073101,0.0005905112],"about_ca_topic_score_codex":5.48535e-7,"about_ca_topic_score_gemma":0.0000011515175,"teacher_disagreement_score":0.79795665,"about_ca_system_score_codex":0.0000018002737,"about_ca_system_score_gemma":0.0000259676,"threshold_uncertainty_score":0.31812721},"labels":[],"label_agreement":null},{"id":"W2392666962","doi":"10.1016/j.jneuroim.2016.05.010","title":"Family-based association study of interleukin 10 (IL10) and interleukin 10 receptor alpha (IL10RA) functional polymorphisms in schizophrenia in Polish population","year":2016,"lang":"en","type":"article","venue":"Journal of Neuroimmunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia (object-oriented programming); Haplotype; Etiology; Transmission disequilibrium test; Interleukin 10; Population; Immunology; Interleukin 10 receptor, alpha subunit; Medicine; Allele; Biology; Genetics; Psychiatry; Gene; Cytokine","score_opus":0.026289559649274697,"score_gpt":0.25028728805005374,"score_spread":0.22399772840077903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2392666962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99756366,0.00008665677,0.000022323571,0.0012950436,0.0007496772,0.0001978475,0.000009818723,0.000015030081,0.000059960832],"genre_scores_gemma":[0.99928427,0.000040558538,0.000038736805,0.00029067195,0.00005973845,0.000005881874,0.0000016682999,0.000021504418,0.0002569991],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9973308,0.00071850006,0.00096468703,0.000319478,0.00036980922,0.00029673547],"domain_scores_gemma":[0.9980057,0.00072365085,0.00093165826,0.00018539756,0.00010564121,0.000047974296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046123506,0.00019195599,0.0004521221,0.0010166224,0.000043719654,0.000028439485,0.0002919497,0.000158682,0.00024088344],"category_scores_gemma":[0.0017952422,0.00015395245,0.00008935476,0.0004816813,0.00009984762,0.00040416507,0.000085198306,0.00038654538,0.000016411805],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029783836,0.00087437034,0.0916798,0.0000062664253,0.000017677246,0.00003706966,0.00028035024,0.00003266829,0.8944572,0.00009051067,0.00042451537,0.009121152],"study_design_scores_gemma":[0.008269345,0.0019002453,0.9824161,0.00009548522,0.000008899988,0.00002853638,0.00020765746,0.000042640655,0.0062921545,0.00029306277,0.00030264244,0.00014323491],"about_ca_topic_score_codex":0.00011294913,"about_ca_topic_score_gemma":0.00018855825,"teacher_disagreement_score":0.8907363,"about_ca_system_score_codex":0.00028725897,"about_ca_system_score_gemma":0.00009273199,"threshold_uncertainty_score":0.6277999},"labels":[],"label_agreement":null},{"id":"W2396648186","doi":"10.1016/j.psyneuen.2016.05.015","title":"Association of serum interleukin-6 with mental health problems in children exposed to perinatal complications and social disadvantage","year":2016,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Disadvantage; Mental health; Medicine; Cohort; Mood; Mood disorders; Relative risk; Psychiatry; Risk factor; Clinical psychology; Internal medicine; Anxiety; Confidence interval","score_opus":0.01667371374750284,"score_gpt":0.27797096074381406,"score_spread":0.26129724699631124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2396648186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9597673,0.000013358872,0.00011416989,0.03906034,0.00008970882,0.00051790185,0.00016937222,0.000044898323,0.00022296306],"genre_scores_gemma":[0.9978364,0.000072539726,0.00006159743,0.00180206,0.00001149013,0.000040948875,0.000002781381,0.000015824999,0.00015632565],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987159,0.00014687444,0.0002311028,0.00040614285,0.00013110357,0.0003689239],"domain_scores_gemma":[0.9995742,0.000076286015,0.00014312711,0.0001396287,0.000013162008,0.000053625186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003002747,0.00012152399,0.00018461872,0.00015333146,0.00009144495,0.000010502224,0.00017480303,0.000019211782,0.000019483507],"category_scores_gemma":[0.000039502556,0.000092686176,0.00002355044,0.00017892933,0.00012495166,0.00009867777,0.00007306542,0.000093243085,0.000015705917],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017999957,0.00044432576,0.6754939,0.000034253404,0.000020627103,0.0000038917706,0.0020580422,0.0000018620475,0.2896009,0.003606877,0.0011681643,0.027387144],"study_design_scores_gemma":[0.0024221498,0.00056497304,0.98212975,0.000024244366,0.0000014029024,0.00009867715,0.00010115692,0.0000021569704,0.011936638,0.00016369515,0.0024268094,0.00012832753],"about_ca_topic_score_codex":0.000014803327,"about_ca_topic_score_gemma":0.0001859721,"teacher_disagreement_score":0.30663586,"about_ca_system_score_codex":0.000070211,"about_ca_system_score_gemma":0.000018369265,"threshold_uncertainty_score":0.37796327},"labels":[],"label_agreement":null},{"id":"W2398056138","doi":"10.1007/s00018-016-2272-4","title":"Stress transgenerationally programs metabolic pathways linked to altered mental health","year":2016,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"Canadian Institutes of Health Research; Alberta Innovates - Health Solutions; Alberta Centre for Child, Family and Community Research; University of Lethbridge","keywords":"Biology; Mental health; Metabolomics; Psychology; Identification (biology); Downregulation and upregulation; Metabolic pathway; Bioinformatics; Genetics; Computational biology; Gene; Psychiatry","score_opus":0.039422724882533074,"score_gpt":0.2666403598456982,"score_spread":0.22721763496316516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2398056138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9777513,0.0016522538,0.009606226,0.009605353,0.00029112402,0.00053240533,0.000045528104,0.00007424209,0.0004415578],"genre_scores_gemma":[0.99330497,0.00024335441,0.00090922794,0.005338559,0.0000623741,0.00002945543,0.0000054858638,0.0000115891135,0.00009496123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99812275,0.00015401148,0.00021676625,0.0006146908,0.0004692159,0.00042257132],"domain_scores_gemma":[0.9993496,0.000029815725,0.00005842276,0.0001627403,0.000018899427,0.00038054914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002777669,0.00016213443,0.00017301993,0.00011063459,0.00041173553,0.000112938105,0.0003370537,0.00003617849,0.00003045905],"category_scores_gemma":[0.00010904534,0.000107218606,0.00006987514,0.0003651867,0.00038257852,0.00016283258,0.00006062903,0.00004676895,0.000024032928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008085585,0.00006914306,0.00008811706,0.0000074816235,0.0000032287783,0.0000035460564,0.000487073,0.000008023116,0.964742,0.011570002,0.00013787068,0.022875423],"study_design_scores_gemma":[0.00080141186,0.00040514802,0.00069558265,0.000053497155,0.0000038619237,0.0000065391523,0.00022413615,0.00018048708,0.9776058,0.00092640164,0.018774662,0.00032246477],"about_ca_topic_score_codex":0.000012219454,"about_ca_topic_score_gemma":0.000015426449,"teacher_disagreement_score":0.022552958,"about_ca_system_score_codex":0.00000916168,"about_ca_system_score_gemma":0.00019247303,"threshold_uncertainty_score":0.43722478},"labels":[],"label_agreement":null},{"id":"W2406346747","doi":"10.1177/070674371005501118","title":"Re: Antidepressant Pretreatment and Symptomatic Treatment in Interferon Treatment","year":2010,"lang":"en","type":"letter","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Antidepressant; Medicine; Psychiatry; Pharmacology; Internal medicine; Anxiety","score_opus":0.021135533238861418,"score_gpt":0.2500011422807867,"score_spread":0.22886560904192527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2406346747","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24490681,0.0025333746,0.000001549601,0.74724716,0.003058168,0.00070587423,0.000089889465,0.000012346226,0.0014448607],"genre_scores_gemma":[0.7545096,0.001035665,0.00047787162,0.23846176,0.0030653968,0.00006196863,0.00001452553,0.00014868012,0.002224502],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979525,0.00029279783,0.0005808989,0.00035800217,0.0002562143,0.00055955566],"domain_scores_gemma":[0.99846685,0.00022755579,0.0004643146,0.00052089774,0.000024160887,0.00029620875],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014480636,0.0004568821,0.0005485794,0.00051062374,0.00024435145,0.00019843807,0.000501874,0.00055077096,0.00016102828],"category_scores_gemma":[0.000058258447,0.00026822544,0.00023074921,0.00018229593,0.0003104796,0.00009788444,0.00001505476,0.0014246217,0.000018854398],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026827646,0.00067930087,0.04799802,0.0003136758,0.00065152784,0.006494572,0.009380617,0.00004876706,0.00051372976,0.0010788814,0.9067152,0.025857424],"study_design_scores_gemma":[0.012068091,0.011132653,0.02178877,0.0021971625,0.00089390995,0.0041304287,0.0013997913,0.0001169172,0.0050441185,0.025903294,0.9132176,0.002107246],"about_ca_topic_score_codex":0.016097225,"about_ca_topic_score_gemma":0.6036084,"teacher_disagreement_score":0.5875112,"about_ca_system_score_codex":0.0006736862,"about_ca_system_score_gemma":0.0023146477,"threshold_uncertainty_score":0.999977},"labels":[],"label_agreement":null},{"id":"W2407448809","doi":"10.1158/2326-6074.cricimteatiaacr15-a134","title":"Abstract A134: The immunoregulatory enzyme IDO induces resistance to common chemotherapy drugs via base excision repair pathway","year":2016,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Lawson Health Research Institute","funders":"","keywords":"Cancer research; Immune system; Indoleamine 2,3-dioxygenase; Medicine; Immunotherapy; CD8; Immunology; Biology","score_opus":0.05595747684208299,"score_gpt":0.3480774577969711,"score_spread":0.2921199809548881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2407448809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9737039,0.0059043076,0.000021336524,0.016133782,0.0005347496,0.00073250214,0.000034665652,0.00020179676,0.0027329496],"genre_scores_gemma":[0.9903181,0.0018118444,0.000024452636,0.0018162563,0.0001614829,0.00035748942,0.0000011507902,0.000058454694,0.005450773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959915,0.0008484006,0.00041382256,0.00090338173,0.00077548285,0.001067359],"domain_scores_gemma":[0.9962031,0.0018507785,0.0001160752,0.001509039,0.00018682824,0.0001341568],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016561514,0.00027119648,0.00030977782,0.00030506658,0.0008138766,0.00007412082,0.0015965969,0.00024073581,0.0011494207],"category_scores_gemma":[0.0006365545,0.00016225479,0.00015220199,0.00094019854,0.0016306316,0.00026626146,0.00038325824,0.0007727644,0.00062442996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008809224,0.00009254471,0.00010523476,0.000013881598,0.000022719629,0.000019021709,0.00093762396,0.0000010068668,0.8949465,0.000930847,0.011495845,0.09055384],"study_design_scores_gemma":[0.0010827443,0.00013572909,0.03443553,0.00014744961,0.0000014505765,0.0000050685685,0.00032086964,0.0000023298858,0.84576535,0.0022575858,0.115601934,0.00024397243],"about_ca_topic_score_codex":0.00016695862,"about_ca_topic_score_gemma":0.00016655201,"teacher_disagreement_score":0.10410609,"about_ca_system_score_codex":0.00035342795,"about_ca_system_score_gemma":0.00035830506,"threshold_uncertainty_score":0.99976367},"labels":[],"label_agreement":null},{"id":"W2408685783","doi":"10.1007/7854_2016_2","title":"Evidence for Inflammation-Associated Depression","year":2016,"lang":"en","type":"review","venue":"Current topics in behavioral neurosciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":103,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Inflammation; Depression (economics); Tumor necrosis factor alpha; Medicine; Cytokine; Proinflammatory cytokine; Immunology; Oxidative stress; Interleukin; Bioinformatics; Internal medicine; Biology","score_opus":0.387644486491802,"score_gpt":0.4750605538502574,"score_spread":0.08741606735845542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2408685783","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0023270708,0.98844063,0.000060399434,0.00006621921,0.007047994,0.0017815771,0.00010260935,0.0001216492,0.00005181836],"genre_scores_gemma":[0.00071836467,0.9980289,0.000019762794,0.000022605533,0.00024810166,0.0004679063,0.000008287083,0.000031272197,0.00045482448],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964928,0.00035730505,0.00079674745,0.0011786122,0.00055976294,0.0006147548],"domain_scores_gemma":[0.99778885,0.0010746823,0.00054433814,0.00042855254,0.000040974544,0.00012260085],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003392986,0.00044523328,0.00081226655,0.00039054462,0.00025886038,0.0002058703,0.0013338126,0.00022638997,0.000032212025],"category_scores_gemma":[0.0030833536,0.0003080625,0.00037062055,0.000889979,0.00034874675,0.00058106973,0.00023935121,0.00039587304,0.00003271964],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000030189497,0.00013117766,0.00015419474,0.00081113423,2.937226e-7,0.000004694846,0.000023766414,2.8074697e-7,0.00019438667,0.00023567048,0.00013552979,0.99830586],"study_design_scores_gemma":[0.00030853372,0.00011677213,0.00016405107,0.020262064,0.000041919804,0.0000056677686,0.000004027305,0.000018035036,0.00054294564,0.00042347334,0.9775629,0.0005496222],"about_ca_topic_score_codex":0.000003149034,"about_ca_topic_score_gemma":0.000014773286,"teacher_disagreement_score":0.99775624,"about_ca_system_score_codex":0.00014354727,"about_ca_system_score_gemma":0.00030763418,"threshold_uncertainty_score":0.9999372},"labels":[],"label_agreement":null},{"id":"W2408773464","doi":"10.1093/schbul/sbw059","title":"Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases","year":2016,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Human Genome Research Institute; University of Toronto; National Institutes of Health; King's College London; Queen Mary University of London; Harvard University","keywords":"Immune system; Schizophrenia (object-oriented programming); Major histocompatibility complex; Genome-wide association study; Genetic association; Biology; Gene; Immunology; Genetics; Single-nucleotide polymorphism; Medicine; Genotype; Psychiatry","score_opus":0.01972862674500873,"score_gpt":0.2533251300967973,"score_spread":0.23359650335178858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2408773464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9651987,0.0023238126,0.00004915098,0.030058086,0.00067081355,0.00091402355,0.00014521198,0.0003948258,0.00024535318],"genre_scores_gemma":[0.99321914,0.00078097015,0.0008186956,0.0023629619,0.000166592,0.00025601516,0.000021993492,0.00007339845,0.0023002164],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99569654,0.0005035798,0.00091337686,0.0010973085,0.00077947765,0.001009715],"domain_scores_gemma":[0.9959792,0.002481773,0.00037019583,0.00075681804,0.00013502924,0.00027698177],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000464902,0.00053293846,0.0007681879,0.0005236119,0.00032127515,0.00012504733,0.00078316673,0.00015097225,0.00059811445],"category_scores_gemma":[0.008154259,0.00042044403,0.00021510411,0.0010091614,0.00016353132,0.00014405217,0.00046945494,0.00027478408,0.002679091],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0052465345,0.0011222656,0.020893896,0.00007240994,0.0001559252,0.00014833975,0.00090087607,0.000215781,0.9460689,0.00077466265,0.01596204,0.008438371],"study_design_scores_gemma":[0.010756421,0.00023459714,0.85628057,0.00026747436,0.000042087388,0.000005544261,0.00021054629,0.000012815872,0.07812628,0.0009834307,0.051996995,0.0010832383],"about_ca_topic_score_codex":0.000038677026,"about_ca_topic_score_gemma":0.00006090852,"teacher_disagreement_score":0.86794263,"about_ca_system_score_codex":0.0007148301,"about_ca_system_score_gemma":0.00012108216,"threshold_uncertainty_score":0.99982476},"labels":[],"label_agreement":null},{"id":"W2408809560","doi":"10.1002/gps.4512","title":"Immunological biomarkers associated with brain structure and executive function in late‐life depression: exploratory pilot study","year":2016,"lang":"en","type":"article","venue":"International Journal of Geriatric Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Minority Health and Health Disparities; National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Center for Research Resources; National Institute of Mental Health; National Institute on Aging; Washington University in St. Louis; National Institutes of Health; Syngenta Foundation for Sustainable Agriculture","keywords":"Depression (economics); Psychology; Late life depression; Executive functions; Brain function; Exploratory research; Clinical psychology; Executive dysfunction; Gerontology; Neuroscience; Psychiatry; Medicine; Cognition; Neuropsychology","score_opus":0.017778128891724553,"score_gpt":0.2532307683892626,"score_spread":0.23545263949753806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2408809560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99487495,0.00038964054,0.00022969885,0.002224583,0.0019619134,0.0001623426,0.000018883988,0.000021899206,0.00011606167],"genre_scores_gemma":[0.9989868,0.00007210179,0.000058665442,0.0006391658,0.00018420926,0.000003981823,7.84186e-7,0.000014203852,0.000040129285],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982663,0.00030746654,0.0004405915,0.0002760434,0.0005328683,0.00017673572],"domain_scores_gemma":[0.99881315,0.00036843377,0.00050024927,0.000098296754,0.00012770493,0.00009219078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027900343,0.00016482525,0.00020723688,0.00040481976,0.00005872931,0.000054899258,0.0003508823,0.00006424485,0.00009670416],"category_scores_gemma":[0.00068496156,0.000096357704,0.000044155902,0.0003305955,0.000103022016,0.00043137147,0.00007098972,0.00022711857,0.0000025408788],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015484893,0.0034982234,0.7847684,0.000007635002,0.00066105457,0.00029775887,0.0010277777,0.00006370624,0.17547968,0.0005191595,0.004124519,0.014067205],"study_design_scores_gemma":[0.010610557,0.0033058461,0.9794088,0.00015539792,0.000025497813,0.00008611336,0.00093676976,0.000010900856,0.00094293203,0.0041378736,0.00013435248,0.00024493766],"about_ca_topic_score_codex":0.0000054931584,"about_ca_topic_score_gemma":0.000047028258,"teacher_disagreement_score":0.19464044,"about_ca_system_score_codex":0.00008537961,"about_ca_system_score_gemma":0.00017254915,"threshold_uncertainty_score":0.39293534},"labels":[],"label_agreement":null},{"id":"W2409550653","doi":"10.1007/978-1-62703-071-7_14","title":"The MRL Model: An Invaluable Tool in Studies of Autoimmunity–Brain Interactions","year":2012,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Autoimmunity; Neurodegeneration; Immune system; Immunology; Neuroscience; Neuroimmunology; Disease; Autoimmune disease; Systemic lupus erythematosus; Cerebrospinal fluid; Medicine; Antibody; Biology; Pathology","score_opus":0.29957357058799844,"score_gpt":0.5477822365472146,"score_spread":0.24820866595921615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2409550653","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012256103,0.95954525,0.038564082,0.00012850408,0.00046108026,0.0006862711,0.000015762502,0.00002676739,0.00044969568],"genre_scores_gemma":[0.000021913724,0.91010416,0.08893775,0.00039980447,0.000015920696,0.0002953732,0.000009775147,0.00004241181,0.00017288627],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9864916,0.011576273,0.0008693179,0.00048534913,0.00009522159,0.0004822414],"domain_scores_gemma":[0.9941906,0.0045570876,0.0003693312,0.0008208582,0.000032648422,0.000029527091],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003622762,0.00034487294,0.0012905835,0.00041461329,0.000108867076,0.000016975355,0.0009172951,0.0002879152,0.000013132495],"category_scores_gemma":[0.006251641,0.00023275394,0.00025816352,0.0007917774,0.0006146264,0.00008077121,0.00044575875,0.0008501975,0.000005340217],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008526209,0.000148913,0.000002312557,0.00075431075,0.00003598912,0.000006648739,0.00038324384,0.00007965332,0.022607308,0.016326424,0.000027271872,0.9596194],"study_design_scores_gemma":[0.00031993206,0.00014744887,0.0000020387838,0.001087298,0.00009110425,0.000038960177,0.00029470166,0.0011096763,0.0053229127,0.037233476,0.95383286,0.00051957526],"about_ca_topic_score_codex":0.000037062942,"about_ca_topic_score_gemma":0.000103853214,"teacher_disagreement_score":0.9590998,"about_ca_system_score_codex":0.00010977104,"about_ca_system_score_gemma":0.00015872109,"threshold_uncertainty_score":0.94914305},"labels":[],"label_agreement":null},{"id":"W2412732036","doi":"10.1055/s-2003-45124","title":"Regio entorhinalis in Schizophrenia: More Evidence for Migrational Disturbances and Suggestions for a New Biological Hypothesis","year":2003,"lang":"en","type":"article","venue":"Pharmacopsychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Deutsche Forschungsgemeinschaft; Stanley Medical Research Institute","keywords":"White matter; Replicate; Psychology; Gray (unit); Neuroscience; Psychosis; Biology; Psychiatry; Medicine; Nuclear medicine; Magnetic resonance imaging; Statistics; Mathematics; Radiology","score_opus":0.14560537217853606,"score_gpt":0.3617924769539174,"score_spread":0.21618710477538136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2412732036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9770752,0.005921743,0.0030533778,0.011731922,0.00073155825,0.0011609279,0.0001119739,0.00008173334,0.00013155682],"genre_scores_gemma":[0.9819664,0.00057309814,0.014587517,0.0019912138,0.00022670187,0.0003198066,0.0000044050926,0.000016291899,0.00031456372],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9988054,0.00008860171,0.0002144594,0.0004884228,0.00012294202,0.00028015938],"domain_scores_gemma":[0.99839675,0.0012739174,0.00007545915,0.00011234612,0.000020923546,0.00012058444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001674439,0.00016423587,0.00016127466,0.00008470272,0.00017415771,0.00005230584,0.00017632508,0.000059758964,0.000049908656],"category_scores_gemma":[0.0016814622,0.00013948788,0.00009800083,0.0002521268,0.00012842726,0.0002114039,0.000014556764,0.00010060151,0.000003609261],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0061899084,0.0017311275,0.09643678,0.000595691,0.000077048964,0.0000106851385,0.0031703624,0.0001531761,0.38820836,0.19752775,0.2635789,0.04232022],"study_design_scores_gemma":[0.03499267,0.0012629717,0.21060285,0.00082065177,0.00022915607,0.0001941547,0.0018079405,0.0032975848,0.18258433,0.3489616,0.21194509,0.0033010233],"about_ca_topic_score_codex":0.000015997572,"about_ca_topic_score_gemma":0.00004879621,"teacher_disagreement_score":0.20562401,"about_ca_system_score_codex":0.000021283466,"about_ca_system_score_gemma":0.00012892045,"threshold_uncertainty_score":0.56881505},"labels":[],"label_agreement":null},{"id":"W2414179507","doi":"10.1371/journal.pone.0142598","title":"Prolonged Subdural Infusion of Kynurenic Acid Is Associated with Dose-Dependent Myelin Damage in the Rat Spinal Cord","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; McMaster University","funders":"","keywords":"Kynurenic acid; Myelin; Spinal cord; Central nervous system; Astrogliosis; Medicine; Internal medicine; Neuroprotection; Oligodendrocyte; Endocrinology; Anesthesia; Chemistry; Pharmacology; Glutamate receptor","score_opus":0.09490089638723999,"score_gpt":0.27145680265462657,"score_spread":0.1765559062673866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414179507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975862,0.00005498319,0.0000022365405,0.00110677,0.0000326915,0.00049420644,0.000011040122,0.000045313318,0.0006665793],"genre_scores_gemma":[0.9987797,0.000014200651,0.000047084126,0.00085226714,0.000021971075,0.00002815641,0.0000046691903,0.000015409654,0.00023654684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99823385,0.00026536887,0.00021602298,0.00026497408,0.00076074986,0.00025900415],"domain_scores_gemma":[0.99936014,0.00008102038,0.0001471194,0.0002826185,0.00006766408,0.00006144864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003584113,0.00013499387,0.00021710465,0.000084755615,0.000054017415,0.000034019402,0.0003927203,0.00007064247,0.000046751327],"category_scores_gemma":[0.0007841326,0.00008892915,0.000031471427,0.00046626382,0.0001381585,0.00013827386,0.00006898937,0.00026426217,0.00003386221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019122957,0.002261395,0.008667567,0.000031506628,0.00001978694,0.000057235524,0.0020809218,0.0000029502758,0.9839331,0.00007594568,0.00037361117,0.0005836791],"study_design_scores_gemma":[0.0042107487,0.0028817202,0.06688395,0.00022561893,0.00004030902,0.000005872634,0.00069017534,0.00051777496,0.9239002,0.00037449697,0.000022892304,0.0002462385],"about_ca_topic_score_codex":0.000029481425,"about_ca_topic_score_gemma":0.00035588414,"teacher_disagreement_score":0.060032904,"about_ca_system_score_codex":0.000041202326,"about_ca_system_score_gemma":0.00008439477,"threshold_uncertainty_score":0.36264253},"labels":[],"label_agreement":null},{"id":"W2415131480","doi":"10.1038/mp.2016.90","title":"Postmortem evidence of cerebral inflammation in schizophrenia: a systematic review","year":2016,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":362,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Centre for Addiction and Mental Health; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Neuroinflammation; Schizophrenia (object-oriented programming); Microglia; Psychosis; Medicine; Neuroscience; Psychology; Pathology; Psychiatry; Inflammation; Internal medicine","score_opus":0.02992986103902121,"score_gpt":0.31945367917143885,"score_spread":0.2895238181324176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2415131480","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00004489949,0.99514854,0.00008654005,0.00031117065,0.0004898047,0.0035179793,0.000018853309,0.00005853693,0.0003236864],"genre_scores_gemma":[0.00015073131,0.9987124,0.00018137494,0.00042304405,0.000055299184,0.00034258762,0.0000051658008,0.00007296992,0.000056408146],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9952648,0.0012128127,0.0018035206,0.00076221605,0.0005853851,0.00037125679],"domain_scores_gemma":[0.99711037,0.00031099143,0.0012765666,0.0011696733,0.0000400415,0.00009236678],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00054842397,0.0005365254,0.0025970633,0.00040322446,0.000036741083,0.000031825177,0.000992034,0.0002326907,0.00005985869],"category_scores_gemma":[0.0017875775,0.00037732956,0.00083678885,0.0010795535,0.00009688293,0.00019558759,0.00013597532,0.00037713145,0.00029368803],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007702377,0.000039566767,8.786808e-7,0.9751224,0.000024188572,0.000024739182,0.000007182048,9.759654e-8,0.00012693583,0.0030579392,0.000105331645,0.021483056],"study_design_scores_gemma":[0.00027680452,0.000053691067,0.0000012054518,0.9947806,0.0003691809,0.00009756053,0.0000028507625,0.0000012006809,0.00012328311,0.00048146557,0.0034041388,0.00040801978],"about_ca_topic_score_codex":0.0000031547602,"about_ca_topic_score_gemma":0.000007493008,"teacher_disagreement_score":0.021075038,"about_ca_system_score_codex":0.00007958792,"about_ca_system_score_gemma":0.0005492292,"threshold_uncertainty_score":0.99986786},"labels":[],"label_agreement":null},{"id":"W2419857233","doi":"10.1016/j.coph.2016.06.001","title":"Inflammation and the microbiome: implications for depressive disorders","year":2016,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Royal Ottawa Mental Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Microbiome; Inflammation; Medicine; Bioinformatics; Biology; Immunology","score_opus":0.09310128831203901,"score_gpt":0.4313205772834371,"score_spread":0.3382192889713981,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2419857233","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000075486637,0.9882617,0.00043697222,0.0022031488,0.0054948027,0.0032559726,0.00023437389,0.00003642605,0.00006904748],"genre_scores_gemma":[0.000045480916,0.99624217,0.000007201361,0.000047486003,0.00044533194,0.0030910769,0.00005911358,0.000027183438,0.000034960183],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981857,0.00046975198,0.00047772517,0.0005154677,0.000051211882,0.00030015007],"domain_scores_gemma":[0.997209,0.0021676405,0.00037162405,0.00018231515,0.000020688994,0.000048721013],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018788097,0.00026414607,0.00055845384,0.00024057571,0.0001649367,0.00003072705,0.00042790285,0.00013895014,0.00003579927],"category_scores_gemma":[0.00023266023,0.00015873912,0.00019339152,0.00028564525,0.0005071845,0.00009279887,0.00014762521,0.00024043221,0.000027435588],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002306564,0.0000355653,0.0000016973371,0.0032307077,0.000011309533,1.9727509e-8,0.000048762104,2.9340964e-7,0.00022709058,0.0075819134,0.0071342285,0.98170537],"study_design_scores_gemma":[0.0024104998,0.000012414012,0.000008463482,0.0011581227,0.000045464163,0.0000072610374,0.000002456237,0.000008185472,0.0000637411,0.0033172986,0.9927754,0.00019069464],"about_ca_topic_score_codex":6.610915e-7,"about_ca_topic_score_gemma":7.893757e-7,"teacher_disagreement_score":0.9856412,"about_ca_system_score_codex":0.00005447757,"about_ca_system_score_gemma":0.00011693589,"threshold_uncertainty_score":0.6473194},"labels":[],"label_agreement":null},{"id":"W2462592197","doi":"10.1080/15622975.2016.1190867","title":"Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition","year":2016,"lang":"en","type":"review","venue":"The World Journal of Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":335,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Wellcome Trust","keywords":"Neurocognitive; Neurochemistry; Anxiety; Neuroscience; Psychology; Endophenotype; Biomarker; Psychiatry; Clinical psychology; Neurology; Cognition; Biology","score_opus":0.06041478086345764,"score_gpt":0.3240209602768214,"score_spread":0.2636061794133638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2462592197","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.029330641,0.96067744,0.00002669397,0.0058086026,0.001899361,0.0014605606,0.0003349159,0.00005927722,0.00040247582],"genre_scores_gemma":[0.0049417894,0.99232656,0.0001508602,0.0017755564,0.00056240463,0.00004202942,0.000010845558,0.00003517954,0.00015479903],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99633634,0.0010212568,0.0011738613,0.00075321394,0.00017072594,0.0005445825],"domain_scores_gemma":[0.99597096,0.0021798827,0.0013024749,0.00028178366,0.000048269303,0.00021662943],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00049141404,0.0005821994,0.0012559406,0.0001452191,0.0004421552,0.000057294186,0.00059417443,0.0002786727,0.00008329048],"category_scores_gemma":[0.00087422685,0.00027172957,0.0005654544,0.00028878637,0.0012890903,0.000046401074,0.00031106675,0.0007675394,0.000005220456],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013938594,0.000471364,0.00009697478,0.0016678191,0.0001397319,0.00001790837,0.000022211187,4.328467e-7,0.0027790465,0.001338824,0.019714255,0.9723576],"study_design_scores_gemma":[0.0011186948,0.0014478952,0.0002352551,0.0011097635,0.00012507082,0.0004946717,0.00003688456,0.000002214859,0.0000146505645,0.007942243,0.98707175,0.00040091408],"about_ca_topic_score_codex":5.0017115e-7,"about_ca_topic_score_gemma":0.0000026093312,"teacher_disagreement_score":0.9719567,"about_ca_system_score_codex":0.000017579414,"about_ca_system_score_gemma":0.00011476217,"threshold_uncertainty_score":0.9999735},"labels":[],"label_agreement":null},{"id":"W2465910153","doi":"10.1128/jvi.00994-16","title":"Kynurenine Reduces Memory CD4 T-Cell Survival by Interfering with Interleukin-2 Signaling Early during HIV-1 Infection","year":2016,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University Health Centre; Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Government of Canada","keywords":"Kynurenine; Biology; Kynurenine pathway; Immune system; T cell; Jurkat cells; Immunology; Catabolism; Cell biology; Tryptophan; Biochemistry; Metabolism","score_opus":0.011028115843913588,"score_gpt":0.22118947836043482,"score_spread":0.21016136251652123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2465910153","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99620366,0.0000652402,0.0018561665,0.00067922554,0.00054651074,0.00005309564,0.0000027988406,0.000028212151,0.00056507817],"genre_scores_gemma":[0.9989771,0.00006423346,0.00006772544,0.00012177795,0.00020562352,0.000001711761,1.4824464e-7,0.000023373006,0.00053827226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987392,0.00018672038,0.00037337418,0.00021890095,0.00020160165,0.00028019946],"domain_scores_gemma":[0.9991374,0.0002129422,0.00039885292,0.00010890206,0.000046681565,0.000095223695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020966594,0.00015413253,0.00025806433,0.00021165168,0.00007906975,0.000033887798,0.00023241062,0.000080268364,0.00013114572],"category_scores_gemma":[0.00015300086,0.00009632687,0.00008582421,0.00012948262,0.00017007175,0.00036148436,0.00005642762,0.00028449376,0.000027824755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065010093,0.00008261263,0.0020183583,0.000009582876,0.0000137025545,0.00006307613,0.00026840708,0.000055513363,0.9954362,0.0000076119786,0.00019008333,0.0012047838],"study_design_scores_gemma":[0.0019548917,0.0010226216,0.0058150454,0.00008049897,0.000011978817,0.00032175347,0.00005519869,0.0000065435834,0.9901507,0.000049312865,0.00039771947,0.00013374134],"about_ca_topic_score_codex":0.000007106419,"about_ca_topic_score_gemma":0.0000071072045,"teacher_disagreement_score":0.005285473,"about_ca_system_score_codex":0.00005365721,"about_ca_system_score_gemma":0.000031671636,"threshold_uncertainty_score":0.39280957},"labels":[],"label_agreement":null},{"id":"W2466989152","doi":"10.1016/j.jpsychires.2016.07.006","title":"Circulating biosignatures of late-life depression (LLD): Towards a comprehensive, data-driven approach to understanding LLD pathophysiology","year":2016,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Mental Health; National Institute on Aging; National Institutes of Health; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Proteostasis; Biomarker; Internal medicine; Medicine; Bioinformatics; Psychology; Biology; Biochemistry","score_opus":0.27390372154593867,"score_gpt":0.40367719939865415,"score_spread":0.12977347785271548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2466989152","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97547346,0.00095238007,0.016372606,0.0032094303,0.00064572983,0.0004585921,0.000054256485,0.000022895865,0.0028106314],"genre_scores_gemma":[0.9949369,0.00038495168,0.0040162196,0.00030298205,0.00028976472,0.0000029639064,0.0000012716149,0.000026217009,0.000038722017],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9960774,0.00086582825,0.0006917264,0.000512231,0.0012999305,0.0005528912],"domain_scores_gemma":[0.9973757,0.0010276609,0.00042728506,0.0006177113,0.00023470826,0.00031692476],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010162619,0.00017026025,0.00042028588,0.0010126048,0.00024787532,0.000054092616,0.0014616133,0.00015105888,0.000039843006],"category_scores_gemma":[0.001879174,0.0001042876,0.00014377991,0.0014229772,0.00024584474,0.00027883588,0.0005463533,0.0006208114,0.000011273566],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007071061,0.0004064401,0.0016152272,0.00016101402,0.000040248662,0.000039970906,0.0004127622,0.000732249,0.9668389,0.0025631837,0.018678995,0.007803924],"study_design_scores_gemma":[0.05383411,0.014986077,0.3202878,0.0048925923,0.00037769944,0.0015011103,0.021917544,0.037684966,0.23323749,0.2906448,0.015026531,0.005609279],"about_ca_topic_score_codex":0.000017836011,"about_ca_topic_score_gemma":0.0000015706308,"teacher_disagreement_score":0.7336014,"about_ca_system_score_codex":0.00010154547,"about_ca_system_score_gemma":0.00036795635,"threshold_uncertainty_score":0.4252725},"labels":[],"label_agreement":null},{"id":"W2469221759","doi":"10.5455/bcp.20160520092044","title":"The Neuroinflammation Perspective of Depression: Reuniting the Outstanding Mechanisms of the Pathophysiology","year":2016,"lang":"en","type":"article","venue":"Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Neuroinflammation; Perspective (graphical); Depression (economics); Pathophysiology; Psychology; Neuroscience; Medicine; Pathology; Computer science; Disease; Artificial intelligence","score_opus":0.04602643419604933,"score_gpt":0.37591924079810796,"score_spread":0.3298928066020586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2469221759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9048635,0.00034218162,0.0009530868,0.076996975,0.0062854216,0.0014495944,0.00006483484,0.00008160259,0.008962839],"genre_scores_gemma":[0.994574,0.0010860512,0.00017131185,0.0033273583,0.000308343,0.000048664053,3.8553955e-7,0.000039337498,0.00044456363],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99215746,0.003728641,0.0022527578,0.0007511546,0.00055762,0.00055239385],"domain_scores_gemma":[0.97659194,0.019555151,0.0024107564,0.00096124527,0.00037030247,0.00011061689],"candidate_categories":["metaresearch","sts"],"consensus_categories":[],"category_scores_codex":[0.0028019575,0.00031855752,0.0007671367,0.00008423627,0.0004682239,0.0000121801495,0.001903564,0.0003026229,0.0003810584],"category_scores_gemma":[0.0114508625,0.00013788679,0.00068357517,0.0004222427,0.0030614303,0.000050915525,0.00053528755,0.00077460846,0.000039382383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033387737,0.0003983065,0.00089235854,0.000041623072,0.00009422685,0.000007640381,0.00041951606,0.000046279078,0.9128557,0.054719213,0.009354898,0.017831497],"study_design_scores_gemma":[0.016393587,0.0018662518,0.025254643,0.00035845992,0.00028081058,0.000054961165,0.0036260146,0.0004446152,0.70253897,0.198666,0.049778096,0.00073756074],"about_ca_topic_score_codex":0.000018189217,"about_ca_topic_score_gemma":0.0000054818915,"teacher_disagreement_score":0.21031667,"about_ca_system_score_codex":0.000029326597,"about_ca_system_score_gemma":0.00014312316,"threshold_uncertainty_score":0.9996517},"labels":[],"label_agreement":null},{"id":"W2471987962","doi":"10.1111/hdi.12442","title":"Potential role of costimulatory pathways in immune dysfunction in hemodialysis patients","year":2016,"lang":"en","type":"letter","venue":"Hemodialysis International","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Nephrology; Medicine; Transplantation; Dialysis; Internal medicine; Hemodialysis; Intensive care medicine","score_opus":0.011173590751508429,"score_gpt":0.21880522082983278,"score_spread":0.20763163007832436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2471987962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9360134,0.0001659016,0.00042495586,0.045491014,0.0043217936,0.000952551,0.001031844,0.0001200355,0.011478503],"genre_scores_gemma":[0.964178,0.00008655847,0.00004433744,0.033322044,0.0012791863,0.00007005783,0.00048016483,0.000059391135,0.0004802035],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99605536,0.00032622507,0.001054216,0.0008906039,0.0012064703,0.0004671339],"domain_scores_gemma":[0.99837166,0.000361376,0.00059048407,0.00048124147,0.00015077999,0.000044440112],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025676575,0.0003977199,0.00066498324,0.0016305138,0.000044265093,0.000050806222,0.00086276035,0.00060789863,0.00082617963],"category_scores_gemma":[0.0006202526,0.00037504276,0.00046772027,0.00054245204,0.00016950163,0.0003104351,0.00021640486,0.0008023988,0.00015207444],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016340473,0.0029901871,0.06498775,0.00026771487,0.0005514748,0.00068209576,0.0016563071,0.004814772,0.5927419,0.00072966807,0.15647209,0.17247197],"study_design_scores_gemma":[0.033988718,0.00040078102,0.13482505,0.001256253,0.00031429878,0.000024186009,0.00020571821,0.02186499,0.3408828,0.021746589,0.44001326,0.004477365],"about_ca_topic_score_codex":0.00011688024,"about_ca_topic_score_gemma":0.000032541175,"teacher_disagreement_score":0.28354117,"about_ca_system_score_codex":0.00043439667,"about_ca_system_score_gemma":0.00011259065,"threshold_uncertainty_score":0.9998701},"labels":[],"label_agreement":null},{"id":"W2472893188","doi":"10.1016/j.jpsychires.2016.07.009","title":"Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis","year":2016,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Douglas Mental Health University Institute; McGill University","funders":"National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"microRNA; Gene; Biology; Biological pathway; Gene regulatory network; Gene expression; Antidepressant; Computational biology; Bioinformatics; Genetics; Neuroscience","score_opus":0.03610550810632803,"score_gpt":0.35777935053731297,"score_spread":0.32167384243098496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2472893188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922355,0.0005731921,0.0018659283,0.004549398,0.0002235671,0.00037237574,0.000015880592,0.000010697134,0.00015350626],"genre_scores_gemma":[0.99651426,0.00045905702,0.0018293211,0.00011475089,0.00042472937,0.000032418196,4.6414422e-7,0.000018741266,0.0006062596],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9953933,0.0019390692,0.00059818086,0.00040411548,0.0010382909,0.0006270416],"domain_scores_gemma":[0.9977516,0.0011603531,0.00023421788,0.00035319087,0.00018000744,0.00032062543],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017074472,0.00016205564,0.00034770992,0.0015625375,0.000223476,0.00008423494,0.00048834214,0.0001002656,0.00019586223],"category_scores_gemma":[0.00091949344,0.00009669758,0.00027387918,0.0036268767,0.00008493517,0.00019956318,0.00008582462,0.0002723285,0.000023364766],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022378847,0.0013826452,0.08894135,0.000012660705,0.00020678564,0.0005047281,0.00079620874,0.003335912,0.86652684,0.00008934152,0.005072861,0.0107518],"study_design_scores_gemma":[0.018512405,0.011992098,0.73592865,0.00029440477,0.00038806148,0.00025899542,0.0002825748,0.000557212,0.22545666,0.0032010986,0.0025207074,0.0006071],"about_ca_topic_score_codex":0.000040946525,"about_ca_topic_score_gemma":0.00006918831,"teacher_disagreement_score":0.6469873,"about_ca_system_score_codex":0.00026105216,"about_ca_system_score_gemma":0.00021721449,"threshold_uncertainty_score":0.39432126},"labels":[],"label_agreement":null},{"id":"W2475360113","doi":"10.1097/qad.0000000000001168","title":"Combination antiretroviral therapy and indoleamine 2,3-dioxygenase in HIV infections","year":2016,"lang":"en","type":"letter","venue":"AIDS","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Kynurenine; Kynurenine pathway; Immunology; Biology; Biochemistry; Tryptophan","score_opus":0.024900352061479645,"score_gpt":0.25039481159208266,"score_spread":0.22549445953060301,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2475360113","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8347809,0.00019491356,0.00008196311,0.15978515,0.0005397866,0.00047820143,0.00007787941,0.00014995906,0.0039112666],"genre_scores_gemma":[0.6740688,0.00050310843,0.000017732104,0.32050163,0.00059608446,0.00003931917,0.00003240409,0.000044706623,0.004196234],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99873614,0.00017069279,0.00018056734,0.0004220404,0.00019887171,0.00029169593],"domain_scores_gemma":[0.9993885,0.00025585218,0.000080626334,0.00023202886,0.000014692912,0.000028311324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083956016,0.00020720212,0.00020675502,0.00037511755,0.00007565821,0.000057741985,0.00016433076,0.00031403932,0.00009207721],"category_scores_gemma":[0.00016292508,0.00016431937,0.000055514683,0.0003020428,0.0001610272,0.00018691408,0.000046948284,0.00058315875,0.00008171337],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004349517,0.00026967187,0.01034735,0.00009065325,0.000016130842,0.00028260605,0.00027838975,5.0658036e-7,0.10351405,0.0022555203,0.78978276,0.09311888],"study_design_scores_gemma":[0.0042942204,0.0010598741,0.01440289,0.00012470422,0.0000030998624,0.000036189005,0.0000146767325,0.00002533212,0.068153545,0.0033379362,0.9078825,0.00066499144],"about_ca_topic_score_codex":0.000022702243,"about_ca_topic_score_gemma":0.0000030864412,"teacher_disagreement_score":0.16071647,"about_ca_system_score_codex":0.00003578586,"about_ca_system_score_gemma":0.00003120594,"threshold_uncertainty_score":0.67007494},"labels":[],"label_agreement":null},{"id":"W2477421061","doi":"10.1007/s11064-016-2009-7","title":"Kynurenic Acid Induces Impairment of Oligodendrocyte Viability: On the Role of Glutamatergic Mechanisms","year":2016,"lang":"en","type":"article","venue":"Neurochemical Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Kynurenic acid; Glutamatergic; Glutamate receptor; Neuroscience; Biology; Central nervous system; Oligodendrocyte; Cell biology; Receptor; Chemistry; Pharmacology; Myelin; Biochemistry","score_opus":0.05348166404294938,"score_gpt":0.321248131488069,"score_spread":0.26776646744511967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2477421061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957885,0.000027402242,0.00001493105,0.0015362604,0.000042982734,0.0003451712,0.000018622932,0.00002839774,0.0021977331],"genre_scores_gemma":[0.99956733,0.00005568164,0.00001852224,0.00017568751,0.000021589574,0.00004420347,2.8201373e-7,0.000018534934,0.00009815785],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99703157,0.0004635751,0.00029475658,0.00047914195,0.0012220579,0.0005088734],"domain_scores_gemma":[0.99704635,0.002045397,0.000076521115,0.00061187934,0.00009703533,0.00012282254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006057567,0.00013819293,0.00019721025,0.00013226915,0.00008624041,0.00001782796,0.0009071918,0.00009412955,0.0003072575],"category_scores_gemma":[0.003009908,0.0000722536,0.000111458394,0.0004969776,0.0006430374,0.000064138905,0.00034990004,0.00033558416,0.0000906028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021748981,0.00024076848,0.000020358995,0.000021699138,0.0000028566417,0.000002526298,0.000104779734,1.7565594e-7,0.9822878,0.014673443,0.00009170473,0.0023363773],"study_design_scores_gemma":[0.0003282242,0.0004561574,0.0002340169,0.000045170713,0.0000013950167,0.000003421461,0.000079364116,0.000018338955,0.9554242,0.04308813,0.00025125116,0.000070358205],"about_ca_topic_score_codex":0.0000072641637,"about_ca_topic_score_gemma":7.6179884e-7,"teacher_disagreement_score":0.028414687,"about_ca_system_score_codex":0.000043629614,"about_ca_system_score_gemma":0.00008273506,"threshold_uncertainty_score":0.36033583},"labels":[],"label_agreement":null},{"id":"W2482548809","doi":"10.1371/journal.pone.0160455","title":"Socioeconomic Disadvantage Moderates the Association between Peripheral Biomarkers and Childhood Psychopathology","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"TBARS; CBCL; Psychopathology; sed; Internal medicine; Brain-derived neurotrophic factor; Medicine; Child Behavior Checklist; Psychology; Neurotrophic factors; Endocrinology; Clinical psychology; Oxidative stress; Lipid peroxidation","score_opus":0.024482767570969136,"score_gpt":0.23615005719383003,"score_spread":0.2116672896228609,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2482548809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903847,0.000055934008,0.00003968584,0.008214032,0.000042636766,0.00018461961,0.00004693689,0.00006116245,0.0009702947],"genre_scores_gemma":[0.9982489,0.00019455691,0.0000679649,0.00084913813,0.000094429255,0.000018834182,0.0000014159303,0.000014816569,0.0005099941],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991276,0.00012504538,0.00012734941,0.00027806984,0.00011362503,0.00022829138],"domain_scores_gemma":[0.99927306,0.00044310186,0.00008680908,0.00014503021,0.000008842257,0.000043128864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013158115,0.000099060155,0.00013947555,0.000027744627,0.00017612152,0.000046730725,0.00014361323,0.0000648207,0.000096968986],"category_scores_gemma":[0.0002355745,0.000059866266,0.000033913348,0.00003935863,0.00013378749,0.00015947016,0.000041816827,0.000074380216,0.00009294557],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026445603,0.000346118,0.32459366,0.000008468363,0.00010262991,0.0000013335401,0.0007954233,2.8327867e-7,0.6664951,0.0005399728,0.0002699023,0.006820681],"study_design_scores_gemma":[0.0017686558,0.00012282575,0.8311526,0.000033414843,0.000053847958,0.000002428696,0.00013497147,0.000063364416,0.15802594,0.008183994,0.00017863158,0.00027933271],"about_ca_topic_score_codex":0.0000021872681,"about_ca_topic_score_gemma":0.0000053884974,"teacher_disagreement_score":0.50846916,"about_ca_system_score_codex":0.000056263754,"about_ca_system_score_gemma":0.000012468233,"threshold_uncertainty_score":0.24412754},"labels":[],"label_agreement":null},{"id":"W2484218215","doi":"10.1016/j.schres.2016.06.031","title":"Peripheral immuno-inflammatory abnormalities in ultra-high risk of developing psychosis","year":2016,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Psychosis; Schizophrenia (object-oriented programming); Global Assessment of Functioning; Internal medicine; Interleukin; Flow cytometry; Tumor necrosis factor alpha; Young adult; Medicine; Peripheral; Disease; Immunology; Psychology; Psychiatry; Clinical psychology; Cytokine","score_opus":0.04254749327457231,"score_gpt":0.3194913905993911,"score_spread":0.2769438973248188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2484218215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962327,0.0001534312,0.00007856801,0.0008962953,0.0001882515,0.0002944417,0.0000374523,0.000056464763,0.002062434],"genre_scores_gemma":[0.9974044,0.001013603,0.0005490651,0.000049456583,0.00006731019,0.000069411755,7.818429e-7,0.000029627077,0.00081632735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965715,0.00091061153,0.00042798824,0.0004941648,0.0008348071,0.0007609283],"domain_scores_gemma":[0.99809253,0.0011113652,0.000093543014,0.00049182284,0.00011461178,0.00009612352],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013248504,0.00017247841,0.00023509345,0.0005178692,0.00022455574,0.000056514844,0.00072316284,0.000111357425,0.0003644984],"category_scores_gemma":[0.0016942968,0.00012393293,0.00008564071,0.0008600838,0.00072203256,0.00034678084,0.00012352891,0.00043913632,0.00015435368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019216468,0.00012939774,0.025706885,0.000113807866,0.000019497096,0.000033129058,0.0013323964,0.000007632881,0.858352,0.061765406,0.0007240283,0.049894147],"study_design_scores_gemma":[0.003747848,0.00014540694,0.18291034,0.00029577478,0.0000018626674,0.000008382196,0.00048388858,0.00001223562,0.78708065,0.02315423,0.0018220198,0.00033735958],"about_ca_topic_score_codex":0.0004097496,"about_ca_topic_score_gemma":0.0003850005,"teacher_disagreement_score":0.15720345,"about_ca_system_score_codex":0.00013914898,"about_ca_system_score_gemma":0.00027332682,"threshold_uncertainty_score":0.50538385},"labels":[],"label_agreement":null},{"id":"W2489232577","doi":"10.1016/j.bbi.2016.07.155","title":"Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment","year":2016,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":113,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Wilfrid Laurier University; Centre hospitalier universitaire de Québec","funders":"Ministero della Salute","keywords":"Fluoxetine; Antidepressant; Inflammation; Microglia; Mood; Serotonin reuptake inhibitor; Immune system; Medicine; Depression (economics); Pharmacology; Sickness behavior; Mood disorders; Reuptake inhibitor; Proinflammatory cytokine; Serotonin; Hippocampus; Immunology; Internal medicine; Psychiatry; Anxiety; Receptor","score_opus":0.03158251539845562,"score_gpt":0.27467200451349666,"score_spread":0.24308948911504102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2489232577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99587005,0.000084152045,0.000030588883,0.0032611561,0.00012428443,0.0005674767,0.00002291079,0.000015875026,0.000023474418],"genre_scores_gemma":[0.99891263,0.00005346219,0.0000050965145,0.00046512167,0.000023175116,0.000064073145,1.7429257e-7,0.000009171729,0.00046711008],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9978656,0.0014567119,0.00016164208,0.00019275969,0.00015632312,0.00016696686],"domain_scores_gemma":[0.99716246,0.0022198856,0.00009393302,0.0004734364,0.0000068646073,0.000043396754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010213878,0.00012940742,0.000112403526,0.000026927926,0.0005633004,0.000036640482,0.00021441247,0.00003980958,0.00002377488],"category_scores_gemma":[0.00093974976,0.000052358915,0.0000615461,0.00007683852,0.00033420126,0.000075989046,0.0002665715,0.0000934241,0.000004784259],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027379414,0.000083713574,0.024494946,0.0000037062655,0.0000028408745,4.3259348e-7,0.0010671659,4.4132398e-7,0.9404416,0.00005239131,0.000039252856,0.033539698],"study_design_scores_gemma":[0.00040493134,0.00018626661,0.82325506,0.000023034352,0.0000122637175,0.0000057705943,0.000824905,6.90843e-7,0.17343928,0.000013470109,0.0017611719,0.00007313623],"about_ca_topic_score_codex":0.00008228541,"about_ca_topic_score_gemma":0.000036324578,"teacher_disagreement_score":0.7987601,"about_ca_system_score_codex":0.000042078558,"about_ca_system_score_gemma":0.000022490976,"threshold_uncertainty_score":0.4332508},"labels":[],"label_agreement":null},{"id":"W2489853012","doi":"10.1016/j.atherosclerosis.2016.07.902","title":"Inflammation, depression and atherosclerosis or depression, inflammation and atherosclerosis?","year":2016,"lang":"en","type":"letter","venue":"Atherosclerosis","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Depression (economics); Medicine; Inflammation; Coronary artery disease; Psoriasis; Internal medicine; Cardiology; Positron emission tomography; Diabetes mellitus; Subclinical infection; Coronary atherosclerosis; Risk factor; Disease; Computed tomography angiography; Endothelial dysfunction; Angiography; Radiology; Immunology; Endocrinology","score_opus":0.032245693334314054,"score_gpt":0.244575387611064,"score_spread":0.21232969427674997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2489853012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81094575,0.00062770117,0.0007735594,0.17973046,0.0013005171,0.0031146314,0.00056150364,0.0013984371,0.0015474487],"genre_scores_gemma":[0.6453652,0.02291975,0.0015062614,0.29692128,0.010875417,0.002165523,0.00026063167,0.0016657462,0.018320184],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9921874,0.00078218395,0.0013896195,0.0027379121,0.0013608013,0.0015420972],"domain_scores_gemma":[0.9950123,0.0016624884,0.0011642105,0.0015811084,0.00017752974,0.00040236855],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0005484965,0.0015397231,0.0012338101,0.00051939575,0.001152886,0.00085566094,0.001069901,0.0021173263,0.0006405454],"category_scores_gemma":[0.0011224276,0.0011072081,0.0003096908,0.0006531206,0.0009913507,0.0013402534,0.00083730475,0.0015588418,0.0003024785],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014592652,0.000055194858,0.008532074,0.00043963673,0.000072143725,0.000011305875,0.0012050242,0.000002957284,0.7911126,0.000091458794,0.1370684,0.061263274],"study_design_scores_gemma":[0.005213359,0.00033131955,0.04230165,0.0032228844,0.00020468431,0.00006487394,0.0001235271,0.00014976914,0.40537256,0.0013607983,0.5387027,0.0029518548],"about_ca_topic_score_codex":0.000074704556,"about_ca_topic_score_gemma":0.000046035366,"teacher_disagreement_score":0.4016343,"about_ca_system_score_codex":0.00017855842,"about_ca_system_score_gemma":0.00013738393,"threshold_uncertainty_score":0.9997351},"labels":[],"label_agreement":null},{"id":"W2490223419","doi":"10.1007/978-3-319-32480-7_14","title":"Metabolic-Inflammation Aspects of Depression and Cardiovascular Disease","year":2016,"lang":"en","type":"book-chapter","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University Health Network; University of Toronto","funders":"","keywords":"Inflammation; Major depressive disorder; Medicine; Disease; Insulin resistance; Bioinformatics; Metabolic syndrome; Depression (economics); Diabetes mellitus; Mood; Internal medicine; Endocrinology; Psychiatry; Biology","score_opus":0.01755123391253327,"score_gpt":0.21917006216638307,"score_spread":0.2016188282538498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2490223419","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012049429,0.005171148,0.0004176375,0.00007943202,0.00010557925,0.0003241862,0.000036901005,0.000073874406,0.9925863],"genre_scores_gemma":[0.6728196,0.0058227666,0.000064683896,0.00014773403,0.00028254295,0.000014442172,0.000005391611,0.000082606086,0.3207602],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988133,0.00002618978,0.00018738813,0.00045692807,0.00039269964,0.00012350283],"domain_scores_gemma":[0.9991896,0.000078034325,0.00009635282,0.0004894028,0.000026869186,0.00011971679],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007294292,0.00019842436,0.00031089204,0.00011513016,0.000045604684,0.000016876063,0.00013355316,0.000107693144,0.00040380296],"category_scores_gemma":[0.00013490813,0.00013568593,0.00025331663,0.00001784529,0.00013870095,0.00011259455,0.00009577753,0.000075047385,0.000058786736],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003529044,0.0000064457313,0.000009837718,0.00007798929,0.000066009736,0.000023055161,0.000019028674,0.000005476073,0.019453052,0.87230486,0.0001302867,0.107868664],"study_design_scores_gemma":[0.001402831,0.000030368436,0.0011834615,0.00039937225,0.000319191,0.000011868244,0.00000550621,0.00005272589,0.29712766,0.20662835,0.49209687,0.0007417808],"about_ca_topic_score_codex":0.000002653228,"about_ca_topic_score_gemma":0.0000013873293,"teacher_disagreement_score":0.67182606,"about_ca_system_score_codex":0.000005284598,"about_ca_system_score_gemma":0.000038994363,"threshold_uncertainty_score":0.55331117},"labels":[],"label_agreement":null},{"id":"W2495498299","doi":"10.1007/s10802-016-0187-z","title":"The Role of Family Routines in the Intergenerational Transmission of Depressive Symptoms between Parents and their Adolescent Children","year":2016,"lang":"en","type":"article","venue":"Journal of Abnormal Child Psychology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Psychology; Depressive symptoms; Depression (economics); Developmental psychology; Clinical psychology; Association (psychology); Anxiety; Psychiatry; Psychotherapist","score_opus":0.014654887989780306,"score_gpt":0.27229072062666626,"score_spread":0.25763583263688594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2495498299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957172,0.0014946708,0.0003919293,0.0016837436,0.000126829,0.0001089415,0.000014491355,0.0000020101086,0.0004601704],"genre_scores_gemma":[0.9987238,0.0007080318,0.000010177969,0.0004175165,0.00012874904,0.0000013178175,4.36209e-7,0.0000059730532,0.000004014706],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99876565,0.00028110453,0.00048951665,0.00012505167,0.00018408964,0.00015457282],"domain_scores_gemma":[0.99912435,0.00027649474,0.0003841211,0.00013447486,0.00003970246,0.000040880022],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002838653,0.00010427802,0.00019062398,0.000088377754,0.0000798628,0.0000095322575,0.00045189634,0.000058595073,0.0000069753146],"category_scores_gemma":[0.000068542286,0.00004198488,0.000091740556,0.00010703226,0.00023701527,0.00010475801,0.000028084623,0.00018961041,4.784622e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055559416,0.00036069605,0.7139587,0.0000072155062,0.000053788848,0.0000029209468,0.001759897,0.000015093878,0.13890898,0.00094594306,0.00033147892,0.1430997],"study_design_scores_gemma":[0.0012911533,0.00026209108,0.9540657,0.00010267762,0.000006670586,0.00011176512,0.00010774522,0.000004570034,0.042330004,0.001029283,0.00063614466,0.000052222305],"about_ca_topic_score_codex":0.000002929553,"about_ca_topic_score_gemma":0.0000025058275,"teacher_disagreement_score":0.24010697,"about_ca_system_score_codex":0.0000050100384,"about_ca_system_score_gemma":0.000018763829,"threshold_uncertainty_score":0.17120937},"labels":[],"label_agreement":null},{"id":"W2507671672","doi":"10.1080/08039488.2016.1216163","title":"Personalized medicine in psychiatry","year":2016,"lang":"en","type":"review","venue":"Nordic Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Psychiatry; Personalized medicine; Psychology; Medicine; Bioinformatics","score_opus":0.04520800129608609,"score_gpt":0.3506239863466678,"score_spread":0.3054159850505817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2507671672","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003921336,0.9766708,0.000088524976,0.0038997892,0.013418116,0.0003267128,0.00002048963,0.000025679443,0.005510653],"genre_scores_gemma":[0.000026313437,0.99455416,0.0005338385,0.0011612742,0.0029900006,0.000008935164,0.0000015905621,0.00009495042,0.00062891655],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99532676,0.00064543006,0.0020526852,0.0005455274,0.00086140184,0.00056818203],"domain_scores_gemma":[0.99664795,0.0004513589,0.0020785616,0.00048039967,0.000058960708,0.0002827772],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008336849,0.0006228148,0.0024438696,0.0012383128,0.000088774534,0.000031115327,0.001316111,0.00043475948,0.001370544],"category_scores_gemma":[0.0005760564,0.0003698402,0.0011067203,0.0010339206,0.00042538406,0.00021285012,0.00006827802,0.0013264237,0.00021015864],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008769509,0.00035891694,0.00018436513,0.006422298,0.00009149575,0.000082022896,0.000115067705,1.4747692e-7,0.000013298266,0.01549627,0.06085033,0.9162981],"study_design_scores_gemma":[0.0024736268,0.00028563454,0.000034048342,0.04422051,0.00017053555,0.0011302023,0.00010045137,1.9138882e-7,6.0629293e-7,0.00944279,0.9417349,0.00040647437],"about_ca_topic_score_codex":0.0000050165836,"about_ca_topic_score_gemma":0.000027327716,"teacher_disagreement_score":0.91589165,"about_ca_system_score_codex":0.0001307881,"about_ca_system_score_gemma":0.0020114821,"threshold_uncertainty_score":0.99987537},"labels":[],"label_agreement":null},{"id":"W2510167678","doi":"10.1016/j.neulet.2016.08.015","title":"Interactive effects of ghrelin and ketamine on forced swim performance: Implications for novel antidepressant strategies","year":2016,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Ontario Mental Health Foundation","keywords":"Behavioural despair test; Ketamine; Ghrelin; Antidepressant; Antagonist; Pharmacology; Saline; Medicine; Psychology; Endocrinology; Internal medicine; Hormone; Anesthesia; Receptor; Hippocampus","score_opus":0.02407069880309473,"score_gpt":0.2766494973317613,"score_spread":0.2525787985286666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2510167678","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9787028,0.0000043806167,0.01527609,0.0049999403,0.0003097081,0.00049059995,0.000030466239,0.000047856793,0.00013818656],"genre_scores_gemma":[0.9939939,0.000047076595,0.00012072698,0.005689233,0.000025168625,0.00006974397,3.4370953e-7,0.00001421912,0.000039615483],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998788,0.000029638586,0.00018090717,0.0005287551,0.00016574467,0.00030695664],"domain_scores_gemma":[0.9985147,0.0010076994,0.00012959493,0.00026157306,0.000022690749,0.00006375243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000069574526,0.00015201335,0.00015059972,0.00013288489,0.00016511379,0.000055669625,0.0003196278,0.000029495603,0.0000015334759],"category_scores_gemma":[0.0007436309,0.00010246902,0.000051261028,0.00022982279,0.0005147961,0.0005392437,0.00006161188,0.00007417823,0.0000022238073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053162825,0.00006205317,0.00074810657,0.000043719843,6.6484e-7,6.681896e-7,0.000075207165,0.000040242663,0.99219626,0.0024021065,0.00014697763,0.0042308103],"study_design_scores_gemma":[0.0009338747,0.0003549865,0.1556911,0.00007082972,0.0000037949212,0.000008163834,0.000016453238,0.00038046812,0.8419979,0.0001681748,0.00024400215,0.00013024299],"about_ca_topic_score_codex":0.0000024260169,"about_ca_topic_score_gemma":6.812171e-7,"teacher_disagreement_score":0.15494299,"about_ca_system_score_codex":0.000014350194,"about_ca_system_score_gemma":0.000025349787,"threshold_uncertainty_score":0.41785654},"labels":[],"label_agreement":null},{"id":"W2511508557","doi":"10.1016/j.bbi.2016.07.128","title":"Abstract # 1849 The role of immune system maturation in development of normal behavior in mice","year":2016,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"","keywords":"Immune system; Immunology; Biology","score_opus":0.017908632150133802,"score_gpt":0.24925017462819837,"score_spread":0.23134154247806457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2511508557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99889696,0.00015038796,0.000003465306,0.000047020694,0.000057697984,0.00037955897,0.00001645893,0.000013467296,0.00043499595],"genre_scores_gemma":[0.99980885,0.00001318339,0.00004424381,0.000012342931,0.0000036973538,0.00006808599,0.000002585847,0.0000088007155,0.00003824041],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99884063,0.00014835798,0.0005094177,0.00015234994,0.00016602383,0.00018320876],"domain_scores_gemma":[0.999324,0.00024055332,0.00017111033,0.00021580425,0.000023604915,0.000024889618],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042904788,0.00011527764,0.00017951315,0.00012621412,0.00008311562,0.0000126454715,0.00025899545,0.000071501716,0.00002526922],"category_scores_gemma":[0.00011818158,0.00007464511,0.00004023844,0.00020839016,0.0001566953,0.00018769427,0.000089605455,0.00014523338,0.000003839446],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008808041,0.00026239478,0.016792148,0.00002622494,6.918625e-7,0.0000026760868,0.0011739597,2.0075812e-7,0.94972295,0.00017942624,0.0000012525607,0.031749982],"study_design_scores_gemma":[0.00039126212,0.000017603877,0.55109113,0.000060032427,0.0000023277435,0.000004778593,0.0009626013,0.0000012205022,0.4473793,0.0000047536423,0.000029360295,0.0000556328],"about_ca_topic_score_codex":0.00039549486,"about_ca_topic_score_gemma":0.00023806495,"teacher_disagreement_score":0.534299,"about_ca_system_score_codex":0.000043627188,"about_ca_system_score_gemma":0.00005997897,"threshold_uncertainty_score":0.30439395},"labels":[],"label_agreement":null},{"id":"W2511745659","doi":"10.1016/j.jagp.2016.01.107","title":"Immunological Markers Associated with Brain Health and Treatment Response in Late-Life Depression: Pilot Study","year":2016,"lang":"en","type":"article","venue":"American Journal of Geriatric Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Depression (economics); Dementia; Medicine; Late life depression; Psychiatry; Psychology; Clinical psychology; Internal medicine; Cognition; Disease","score_opus":0.020661942230939662,"score_gpt":0.27581762174464297,"score_spread":0.2551556795137033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2511745659","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869807,0.00062520686,0.000043402535,0.011718715,0.00025358438,0.0002991717,0.0000071173313,0.000026820622,0.00004533485],"genre_scores_gemma":[0.9975407,0.00042991503,0.00023030466,0.0016404032,0.000052858937,0.000008467005,1.6599367e-7,0.000021731748,0.00007545643],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.996556,0.0017740121,0.00058481406,0.0003574454,0.00032919424,0.00039854646],"domain_scores_gemma":[0.997288,0.0012745119,0.00087865285,0.00021445705,0.00002905471,0.000315342],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008268798,0.00022971244,0.00054400787,0.00035114292,0.00012232225,0.000032049862,0.00024662563,0.00002713062,0.00003079597],"category_scores_gemma":[0.00117532,0.0001232188,0.00006217657,0.0008562942,0.00029517917,0.00015176772,0.000040030103,0.00018770783,0.0000032633502],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.09631159,0.008270782,0.757196,0.00000685176,0.00020881464,0.0002503681,0.0019958077,0.000027604408,0.01056876,0.000033697514,0.0013680274,0.1237617],"study_design_scores_gemma":[0.009836253,0.07525146,0.91141117,0.000111439214,0.000013645213,0.0000854245,0.0027601807,0.000003516013,0.00003933349,0.00010477242,0.00015734854,0.00022546647],"about_ca_topic_score_codex":0.000052151296,"about_ca_topic_score_gemma":0.0000535681,"teacher_disagreement_score":0.15421517,"about_ca_system_score_codex":0.00018473493,"about_ca_system_score_gemma":0.00074569805,"threshold_uncertainty_score":0.5024717},"labels":[],"label_agreement":null},{"id":"W2513211100","doi":"10.1111/gbb.12323","title":"<scp>RNA</scp>‐sequencing profiles hippocampal gene expression in a validated model of cancer‐induced depression","year":2016,"lang":"en","type":"article","venue":"Genes Brain & Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton","funders":"Canadian Cancer Society; Sunovion; Canadian Institutes of Health Research; Bristol-Myers Squibb","keywords":"KEGG; Gene; RNA; Biology; Gene expression; Messenger RNA; Computational biology; Genetics; Transcriptome","score_opus":0.06473999233871344,"score_gpt":0.3059688828149919,"score_spread":0.24122889047627846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2513211100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99780333,0.00022898855,0.00062219234,0.00009229836,0.00021743048,0.00070254545,0.000107645894,0.0001303315,0.00009524122],"genre_scores_gemma":[0.997023,0.0001169596,0.0016517709,0.0002067929,0.000057250218,0.0004021899,0.000006094282,0.00006025153,0.00047570743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99731874,0.00023211118,0.0005217964,0.0008102879,0.00050076796,0.0006162904],"domain_scores_gemma":[0.9985225,0.00045985123,0.00026543622,0.0005301706,0.000059719518,0.0001622935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022872134,0.0003190258,0.00035070657,0.00027326396,0.0001252733,0.000031726,0.000548076,0.00022058214,0.00006160991],"category_scores_gemma":[0.0007458257,0.00023136495,0.000121211444,0.0004159907,0.00013851974,0.0003195222,0.00021555119,0.0001592905,0.000018109546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026378122,0.00014485234,0.012734617,0.000019546187,0.0000016534437,0.000022259628,0.00065523,0.00026389028,0.95775443,0.000013849428,0.00019600772,0.028167302],"study_design_scores_gemma":[0.001324772,0.000053180956,0.010606297,0.00024200887,0.000012080993,0.000005905004,0.00017747785,0.0006049045,0.98664117,0.00011484393,0.000056641005,0.00016073536],"about_ca_topic_score_codex":0.00013281383,"about_ca_topic_score_gemma":0.00004967298,"teacher_disagreement_score":0.02888674,"about_ca_system_score_codex":0.0001383205,"about_ca_system_score_gemma":0.0002543818,"threshold_uncertainty_score":0.9434788},"labels":[],"label_agreement":null},{"id":"W2514007471","doi":"10.1176/appi.ajp.2016.16020171","title":"Imaging Microglial Activation in Untreated First-Episode Psychosis: A PET Study With [<sup>18</sup>F]FEPPA","year":2016,"lang":"en","type":"article","venue":"American Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute of Mental Health","keywords":"Translocator protein; Radioligand; Dorsolateral prefrontal cortex; Psychosis; Positron emission tomography; Prefrontal cortex; Psychology; Binding potential; Schizophrenia (object-oriented programming); Hippocampus; Neuroinflammation; Neuroscience; Internal medicine; Medicine; Psychiatry; Inflammation; Receptor; Cognition","score_opus":0.009036220989066864,"score_gpt":0.2543877642336592,"score_spread":0.24535154324459235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2514007471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98909116,0.000030599236,0.0006310798,0.009377204,0.00024331865,0.00026406246,0.0000067864316,0.00003365674,0.00032210708],"genre_scores_gemma":[0.9972806,0.000030753006,0.0012109195,0.0011669617,0.00020146371,0.0000123102,2.357515e-7,0.000039512997,0.000057273242],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979767,0.0002583149,0.00054586923,0.0003911965,0.00042641975,0.0004014761],"domain_scores_gemma":[0.99865055,0.00019271352,0.0006567042,0.00028396852,0.00007002113,0.00014604111],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022687388,0.000253067,0.00037632813,0.0004236377,0.00011605084,0.00005778735,0.00043417705,0.000018682613,0.0001101858],"category_scores_gemma":[0.00013073973,0.00016120222,0.0001090555,0.0008624706,0.00030000845,0.00046364256,0.000029002138,0.00027600102,0.000019861383],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023624243,0.0019843446,0.94876915,0.000012203195,0.000060698476,0.00010263609,0.0013105928,0.00013724565,0.014211597,0.00008804916,0.0028914877,0.028069595],"study_design_scores_gemma":[0.05562818,0.022097597,0.8089384,0.003429974,0.00028872842,0.003307579,0.062984474,0.0006163389,0.029408187,0.0038043468,0.006229472,0.0032667525],"about_ca_topic_score_codex":0.0002628451,"about_ca_topic_score_gemma":0.0004420859,"teacher_disagreement_score":0.13983075,"about_ca_system_score_codex":0.00008550544,"about_ca_system_score_gemma":0.00009766462,"threshold_uncertainty_score":0.6573636},"labels":[],"label_agreement":null},{"id":"W2514584249","doi":"10.12740/pp/61273","title":"Family association study of Transforming Growth Factor Beta1 gene polymorphisms in schizophrenia","year":2016,"lang":"pl","type":"article","venue":"Psychiatria Polska","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Theology; Physics; Philosophy","score_opus":0.02393869471426861,"score_gpt":0.2599058992540746,"score_spread":0.235967204539806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2514584249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915327,0.0007202392,0.00012476447,0.002282795,0.0028343725,0.00148489,0.00038617558,0.00008583842,0.00054823497],"genre_scores_gemma":[0.99820757,0.0004014196,0.0001247967,0.00027921476,0.00033392358,0.00003300155,0.0000025712689,0.00007391163,0.0005435898],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9952114,0.00057489966,0.0012561157,0.0009865471,0.0010289715,0.00094206777],"domain_scores_gemma":[0.997871,0.00057403685,0.00071602716,0.0005472093,0.000082073166,0.00020964535],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00052024424,0.00052100845,0.0007561956,0.0006640299,0.00018360502,0.00007278839,0.0007628235,0.0003309279,0.00017986429],"category_scores_gemma":[0.00048977364,0.00042056493,0.00031106672,0.0012960099,0.00009872496,0.00051363924,0.00007544202,0.00036247307,0.00015016166],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012829128,0.0035938676,0.3523523,0.00005783596,0.00012526,0.0000145886825,0.0048497547,0.000002071595,0.6215085,0.0013534756,0.00045890347,0.014400548],"study_design_scores_gemma":[0.023955608,0.0017081336,0.8970375,0.00017623429,0.00010804577,0.0000028695008,0.00086218317,0.000015209822,0.07378227,0.0012327962,0.0002178,0.0009013622],"about_ca_topic_score_codex":0.00084020133,"about_ca_topic_score_gemma":0.00080323993,"teacher_disagreement_score":0.5477262,"about_ca_system_score_codex":0.0002728,"about_ca_system_score_gemma":0.00026082835,"threshold_uncertainty_score":0.99982464},"labels":[],"label_agreement":null},{"id":"W2515037692","doi":"10.1016/j.resuscitation.2016.07.239","title":"Influence of core body temperature on Tryptophan metabolism, kynurenines, and estimated IDO activity in critically ill patients receiving target temperature management following cardiac arrest","year":2016,"lang":"en","type":"article","venue":"Resuscitation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Critically ill; Core (optical fiber); Targeted temperature management; Tryptophan; Critical illness; Intensive care medicine; Resuscitation; Anesthesia; Cardiopulmonary resuscitation; Biochemistry; Return of spontaneous circulation","score_opus":0.012077063963393074,"score_gpt":0.26501031456325563,"score_spread":0.25293325059986255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2515037692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981296,0.000059656522,0.000009501462,0.0004985419,0.0004126116,0.00050006196,0.00006257782,0.000058902235,0.00026853677],"genre_scores_gemma":[0.9989303,0.00009202853,0.00042704522,0.000410167,0.000029584276,0.00003586224,0.000010211701,0.00002429799,0.000040504077],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99817604,0.00020861033,0.00028254668,0.0005544126,0.00045783815,0.00032055672],"domain_scores_gemma":[0.99896103,0.0003996109,0.000108101376,0.00025067537,0.00018972003,0.000090887246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020531376,0.00023107717,0.0002915283,0.00023880436,0.00012026229,0.000059700506,0.00017099356,0.00013793206,0.0000032620142],"category_scores_gemma":[0.002885552,0.00017443433,0.000072596325,0.00058339775,0.00010825684,0.00052662235,0.000055883014,0.00017845149,0.000004715755],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021116972,0.00015193598,0.011386821,0.00009293872,0.000014068337,0.0000140828115,0.00027996086,0.00020565494,0.9834163,0.001605002,0.00013963027,0.0024824007],"study_design_scores_gemma":[0.0014188424,0.000075084536,0.8354731,0.00046408613,0.000012728506,1.7466031e-7,0.00006276204,0.000045519842,0.16135874,0.0007940525,0.00008167523,0.0002132099],"about_ca_topic_score_codex":0.000011393295,"about_ca_topic_score_gemma":0.000007211816,"teacher_disagreement_score":0.8240863,"about_ca_system_score_codex":0.000058882633,"about_ca_system_score_gemma":0.000028026849,"threshold_uncertainty_score":0.71132255},"labels":[],"label_agreement":null},{"id":"W2516834136","doi":"10.1186/s12974-016-0688-2","title":"Electroconvulsive shock attenuated microgliosis and astrogliosis in the hippocampus and ameliorated schizophrenia-like behavior of Gunn rat","year":2016,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; University of British Columbia; Shimane University","keywords":"Astrogliosis; Neuroscience; Hippocampus; Schizophrenia (object-oriented programming); Electroconvulsive Shock; Neurology; Medicine; Psychology; Psychiatry; Anesthesia; Central nervous system","score_opus":0.013397116802261001,"score_gpt":0.2379246119703223,"score_spread":0.2245274951680613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2516834136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974081,0.000110544584,0.000026029156,0.0020794435,0.00009747117,0.00025415368,0.0000042670126,0.000008637089,0.000011337845],"genre_scores_gemma":[0.99943525,0.0003004385,0.00008344626,0.00011752648,0.000037570815,0.000005689202,3.43241e-7,0.000012380304,0.0000073702968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851483,0.00031308152,0.00052149774,0.00018143843,0.00028464154,0.0001845183],"domain_scores_gemma":[0.99878573,0.0003637324,0.0005528595,0.000130577,0.00011044738,0.000056642933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027606086,0.00014108112,0.00022042655,0.00032007426,0.000064963744,0.000058529287,0.00019565423,0.000055378765,0.000008607361],"category_scores_gemma":[0.00047612822,0.00008394229,0.000056643996,0.00041835866,0.00014756186,0.0004396583,0.000032373224,0.0001836656,0.0000023799712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027297763,0.000052527732,0.0020824776,0.0000115498015,0.0000033982922,0.000047902584,0.00023169865,0.000002290935,0.9649054,0.000034312194,0.0000937414,0.03226172],"study_design_scores_gemma":[0.0028768019,0.00061855797,0.08323405,0.000116312025,0.00003951437,0.0008506702,0.00015992369,0.000056552166,0.9107633,0.0010782022,0.00007182029,0.00013425016],"about_ca_topic_score_codex":0.0000025876438,"about_ca_topic_score_gemma":0.000011224664,"teacher_disagreement_score":0.081151575,"about_ca_system_score_codex":0.000019563298,"about_ca_system_score_gemma":0.000044186767,"threshold_uncertainty_score":0.3423067},"labels":[],"label_agreement":null},{"id":"W2518135013","doi":"10.1101/068684","title":"Cross-disorder analysis of schizophrenia and 19 immune diseases reveals genetic correlation","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Research Foundation of Korea; Suomen Kulttuurirahasto; National Research Foundation; Ministry of Science and ICT, South Korea; Fondation Brain Canada; Fulbright Canada; Ministerio de Economía y Competitividad; Government of Canada; Northwestern University","keywords":"Schizophrenia (object-oriented programming); Immune system; Pleiotropy; Genome-wide association study; Genetic architecture; Disease; Genetic correlation; Correlation; Genetic association","score_opus":0.012216992244311081,"score_gpt":0.2399809257386224,"score_spread":0.22776393349431132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2518135013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99233365,0.003187015,0.0025699148,0.000076270175,0.00035761937,0.000544377,0.0006512647,0.00024606942,0.000033814464],"genre_scores_gemma":[0.9984119,0.00055304775,0.00060739706,0.00010726288,0.00007893209,0.00007193,3.3754895e-7,0.000109238135,0.00005993196],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9972122,0.00020837523,0.0006480605,0.0011354979,0.00039352098,0.00040235528],"domain_scores_gemma":[0.99750376,0.00023261296,0.00067898625,0.0011813942,0.00015010507,0.0002531312],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017798097,0.00045423,0.0007313116,0.00075822964,0.00015748545,0.00016486048,0.00050461583,0.00032981733,0.0003027663],"category_scores_gemma":[0.0010703043,0.0004200971,0.00026879532,0.0011704816,0.0004473892,0.00013950896,0.0004673965,0.00026064427,0.000039503495],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009171452,0.00014847307,0.18360002,0.00023183913,0.0002726651,0.000014995126,0.000007810894,0.00034371813,0.8139732,0.0012425309,0.000056859313,0.000016164191],"study_design_scores_gemma":[0.0007776606,0.000026389516,0.9457975,0.00015224396,0.00044560272,7.641478e-9,8.4584906e-7,0.0008938682,0.051039834,0.000025629282,0.00032925853,0.00051115063],"about_ca_topic_score_codex":0.00003220279,"about_ca_topic_score_gemma":0.0000023555247,"teacher_disagreement_score":0.7629334,"about_ca_system_score_codex":0.000060639788,"about_ca_system_score_gemma":0.00019734805,"threshold_uncertainty_score":0.99982506},"labels":[],"label_agreement":null},{"id":"W2522433741","doi":"10.1101/070730","title":"Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Center for AIDS Research, University of California Los Angeles; National Institutes of Health; National Institute for Health and Care Research; NIHR Cambridge Biomedical Research Centre; Stiftung zur Erforschung der Vaskulären Demenz; Wellcome Trust; Sidney R. Baer, Jr. Foundation; Center for AIDS Research, University of Washington; National Alliance for Research on Schizophrenia and Depression; Gerber Foundation; Autism Speaks","keywords":"Heritability; Linkage disequilibrium; Genetic association; Schizophrenia (object-oriented programming); Context (archaeology); Single-nucleotide polymorphism; Genetic correlation; Genetic epidemiology; Bipolar disorder; Comorbidity","score_opus":0.014676115061547548,"score_gpt":0.2160294108910383,"score_spread":0.20135329582949074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2522433741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99095905,0.0009098919,0.002367528,0.0011418484,0.0018873111,0.001111546,0.0008910269,0.0005631244,0.00016868672],"genre_scores_gemma":[0.9978949,0.00025356503,0.0007840509,0.00064755726,0.00019275166,0.000070347545,0.0000016520085,0.00012426748,0.000030918683],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99630696,0.00035067796,0.00065198535,0.0015675824,0.0005523059,0.00057051826],"domain_scores_gemma":[0.9959056,0.0008072717,0.0008159774,0.0021169067,0.00013895429,0.00021530209],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005209141,0.00052296265,0.00044280663,0.00044369724,0.00035978312,0.00027654512,0.001075156,0.00061128725,0.00009767399],"category_scores_gemma":[0.0027471147,0.0005070277,0.00011108351,0.0006718968,0.00016654137,0.0002407475,0.0006039134,0.00075688836,0.0001843048],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011092622,0.00070321374,0.5275281,0.00038125954,0.00019283975,0.000051092265,0.000029802659,0.0015467413,0.46620375,0.001276827,0.0019548829,0.000020573321],"study_design_scores_gemma":[0.0010280808,0.000047090965,0.98036236,0.00016250182,0.00009579628,4.8983217e-9,9.399449e-7,0.005953224,0.010496849,0.00004150286,0.0010854101,0.00072624517],"about_ca_topic_score_codex":0.000019748813,"about_ca_topic_score_gemma":0.000003139549,"teacher_disagreement_score":0.4557069,"about_ca_system_score_codex":0.0002804678,"about_ca_system_score_gemma":0.00041081902,"threshold_uncertainty_score":0.99973816},"labels":[],"label_agreement":null},{"id":"W2525191723","doi":"10.1007/s11920-016-0736-8","title":"A Slice of the Suicidal Brain: What Have Postmortem Molecular Studies Taught Us?","year":2016,"lang":"en","type":"review","venue":"Current Psychiatry Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Epigenetics; Postmortem studies; Psychology; Neuroscience; Medicine; Psychiatry; Biology; Genetics; Gene","score_opus":0.07723517337964372,"score_gpt":0.38421885310199255,"score_spread":0.30698367972234886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2525191723","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006644465,0.97584546,0.000010466862,0.0010706168,0.020159272,0.0015460727,0.00004344313,0.00008381185,0.00057640224],"genre_scores_gemma":[0.00025135023,0.997727,0.000015574187,0.00061215414,0.00042166506,0.00013721395,0.000010124029,0.00010163008,0.00072333566],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99478745,0.0005331287,0.0017224075,0.0014042942,0.00092593726,0.0006268018],"domain_scores_gemma":[0.994843,0.00033356523,0.0025333539,0.0020139455,0.00011783791,0.00015828646],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004098873,0.0008263731,0.0017967643,0.00020360401,0.00021371662,0.00011313813,0.00091919524,0.00026774677,0.00006230694],"category_scores_gemma":[0.0010196649,0.0004645206,0.001610057,0.00065251754,0.0005475054,0.00033918422,0.0005113327,0.0006242471,0.000039387247],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013486054,0.0006533868,0.00050453277,0.028770626,0.00028916757,0.00023430114,0.00020885642,8.425465e-7,0.00015948144,0.0023333263,0.032932706,0.9338993],"study_design_scores_gemma":[0.00018535419,0.000042799624,0.000040275503,0.026770083,0.0002511944,0.0008462357,0.00009003376,3.241965e-7,0.00018811373,0.0010757484,0.9699263,0.0005835126],"about_ca_topic_score_codex":0.0000026066377,"about_ca_topic_score_gemma":0.0000134326365,"teacher_disagreement_score":0.9369936,"about_ca_system_score_codex":0.000085931846,"about_ca_system_score_gemma":0.00084434694,"threshold_uncertainty_score":0.99978065},"labels":[],"label_agreement":null},{"id":"W2527444812","doi":"10.1007/7854_2016_37","title":"Immune-to-Brain Communication Pathways in Inflammation-Associated Sickness and Depression","year":2016,"lang":"en","type":"review","venue":"Current topics in behavioral neurosciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":207,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Inflammation; Immune system; Sickness behavior; Medicine; Neuroscience; Immunology; Gut–brain axis; Depression (economics); Rheumatoid arthritis; Disease; Psychology; Internal medicine","score_opus":0.1310479136196812,"score_gpt":0.3887708056040721,"score_spread":0.2577228919843909,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2527444812","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15453488,0.8407014,0.000009324532,0.00023200925,0.0025820134,0.0016441044,0.000071393675,0.00010329593,0.000121575475],"genre_scores_gemma":[0.021028044,0.9784832,0.00001433523,0.00004602444,0.00005075152,0.00023078042,0.000014765851,0.000026884702,0.000105194085],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966246,0.0007764011,0.00083064486,0.00086982996,0.00042805512,0.00047046918],"domain_scores_gemma":[0.99842036,0.00051597215,0.00038698097,0.0005324677,0.000026709651,0.00011753855],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046807883,0.00038417112,0.0007549787,0.0006189343,0.00019807152,0.00018752426,0.0011477679,0.00020081198,0.000012755266],"category_scores_gemma":[0.0014365969,0.00029317348,0.00011742974,0.0012867954,0.00033382722,0.00040835649,0.0005429799,0.0005691482,0.000018781144],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002251986,0.0001865985,0.000795767,0.00030966522,1.6347231e-7,0.000008475597,0.00023970354,8.629823e-7,0.000645429,0.0003757747,0.00002594165,0.99740934],"study_design_scores_gemma":[0.0015166157,0.00022437058,0.019773893,0.032794453,0.00004114257,0.00002072434,0.00013801208,0.00007691894,0.0011436716,0.0017279893,0.94064295,0.0018992578],"about_ca_topic_score_codex":0.000020987516,"about_ca_topic_score_gemma":0.00009377453,"teacher_disagreement_score":0.9955101,"about_ca_system_score_codex":0.00012519216,"about_ca_system_score_gemma":0.00015000359,"threshold_uncertainty_score":0.999952},"labels":[],"label_agreement":null},{"id":"W2527804273","doi":"10.1016/j.socscimed.2016.10.001","title":"Psychosocial distress and inflammation: Which way does causality flow?","year":2016,"lang":"en","type":"article","venue":"Social Science & Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Psychosocial; Distress; Causality (physics); Depression (economics); Anxiety; Social support; Inflammation; Clinical psychology; Mental health; Psychology; Medicine; Psychiatry; Social psychology; Immunology","score_opus":0.02054831556186168,"score_gpt":0.3082304178271922,"score_spread":0.28768210226533053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2527804273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.930842,0.000020490235,0.00022816064,0.047934853,0.0010223619,0.00018688226,0.000020505122,0.00009992589,0.01964481],"genre_scores_gemma":[0.99792755,0.00004755066,0.000008669314,0.0005829164,0.0010673881,0.000010374199,7.357987e-7,0.0000065728595,0.00034824247],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980411,0.00008555,0.00021075079,0.00049415114,0.0007659204,0.00040251852],"domain_scores_gemma":[0.99931026,0.00017969575,0.00009503792,0.00015207937,0.00009168638,0.0001712511],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0006037604,0.00013033062,0.00017198133,0.000073419265,0.0007992595,0.00004894601,0.00037301463,0.00006237217,0.0003499703],"category_scores_gemma":[0.0020404328,0.00006669454,0.000022985683,0.00090146495,0.003389414,0.00042523877,0.00006902305,0.00009090769,0.00001801808],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003600872,0.00003275276,0.004411764,0.000017996988,0.000002028639,0.000005197849,0.0105535425,7.740168e-8,0.74091935,0.03475658,0.001902991,0.2073617],"study_design_scores_gemma":[0.009911608,0.0004996133,0.4429207,0.000450616,0.0000480845,0.00002563813,0.00565339,0.00014164501,0.3164719,0.15080002,0.07142017,0.0016565815],"about_ca_topic_score_codex":0.000042293435,"about_ca_topic_score_gemma":0.00013675311,"teacher_disagreement_score":0.43850896,"about_ca_system_score_codex":0.00006431159,"about_ca_system_score_gemma":0.000081016966,"threshold_uncertainty_score":0.9993228},"labels":[],"label_agreement":null},{"id":"W2528997020","doi":"10.1002/ajmg.b.32494","title":"Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression","year":2016,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Medical Research Council; H. Lundbeck A/S; Canada Research Chairs; European Commission; Engineering and Physical Sciences Research Council; Canadian Institutes of Health Research; National Institute for Health and Care Research; King's College London; Nova Scotia Health Research Foundation; GlaxoSmithKline","keywords":"Escitalopram; Antidepressant; Computational biology; Venlafaxine; Nortriptyline; Citalopram; Major depressive disorder; Feature selection; Multiple comparisons problem; Biology; Bioinformatics; Computer science; Machine learning; Pharmacology; Mathematics; Statistics; Neuroscience","score_opus":0.03317260758836265,"score_gpt":0.31806030717173656,"score_spread":0.2848876995833739,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2528997020","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959244,0.0017659181,0.0014151954,0.00049812987,0.00009150827,0.00019853501,0.00008623184,0.0000051996813,0.000014886355],"genre_scores_gemma":[0.9893759,0.008279024,0.0022137214,0.00006128873,0.00003777614,0.000003334,8.43903e-7,0.000020272395,0.0000078592475],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9958724,0.0009945112,0.0012798738,0.00043971086,0.0010783524,0.0003351986],"domain_scores_gemma":[0.996949,0.0007973699,0.0012658939,0.00046681587,0.0001193037,0.00040162177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033940436,0.00030476518,0.0011211868,0.00088062976,0.000036515077,0.000008856538,0.0005184832,0.00009045276,0.000019497236],"category_scores_gemma":[0.00018839662,0.00018983927,0.00029026615,0.0013111762,0.0009516798,0.000030485906,0.0000860192,0.0001503358,2.9083495e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004740683,0.002270627,0.19621962,0.000020364778,0.00036867862,0.00004595379,0.002081117,0.026825184,0.67622274,0.00003817612,0.000014247089,0.091152616],"study_design_scores_gemma":[0.007032457,0.028957138,0.66497576,0.0001320835,0.0012476114,0.00009958224,0.00060593046,0.03220606,0.26392052,0.00016425611,0.00019162522,0.0004669901],"about_ca_topic_score_codex":0.000027450098,"about_ca_topic_score_gemma":0.000064197775,"teacher_disagreement_score":0.46875614,"about_ca_system_score_codex":0.000036626545,"about_ca_system_score_gemma":0.0004412639,"threshold_uncertainty_score":0.7741421},"labels":[],"label_agreement":null},{"id":"W2529974648","doi":"10.4137/ijtr.s38355","title":"The Kynurenine Pathway is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy","year":2016,"lang":"en","type":"review","venue":"International Journal of Tryptophan Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":168,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; McGill University; McGill University Health Centre","funders":"","keywords":"Immune system; Immune privilege; Kynurenine; Immunotherapy; Immunology; Biology; Inflammation; Cancer immunotherapy; Cancer; Immune tolerance; Autoimmunity; Indoleamine 2,3-dioxygenase; Cancer research; Genetics","score_opus":0.19206383362528448,"score_gpt":0.479232459803875,"score_spread":0.2871686261785905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2529974648","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0037312084,0.9876142,0.00004019143,0.0065597137,0.0005388714,0.0011173208,0.00019584673,0.000008099281,0.00019452201],"genre_scores_gemma":[0.009084392,0.9893124,0.000050264356,0.00009435288,0.00037626378,0.0004075577,0.000005168114,0.000052165815,0.0006174432],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963934,0.00053088856,0.0012679494,0.00043559313,0.0008257174,0.00054646813],"domain_scores_gemma":[0.9943254,0.0040327352,0.0006475764,0.00034558188,0.00054642523,0.000102276834],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019760043,0.00029207303,0.0007788207,0.0012548853,0.00021218251,0.00031572737,0.002224173,0.0001998532,0.00008433698],"category_scores_gemma":[0.0009530984,0.0001766162,0.00039892417,0.00070841896,0.00037200528,0.0002502346,0.00022946052,0.0010088535,0.0000105183735],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069784914,0.00016836883,0.00009974334,0.00024918004,0.00009374123,0.000023239285,0.0001907704,7.6932304e-7,0.006648533,0.0030706502,0.00069198705,0.9880652],"study_design_scores_gemma":[0.0045469203,0.0001679471,0.0010068049,0.00608626,0.000008172839,0.00013167833,0.00005043628,0.00000995085,0.002909872,0.0064404756,0.9783594,0.00028211006],"about_ca_topic_score_codex":0.000034787237,"about_ca_topic_score_gemma":0.00016698644,"teacher_disagreement_score":0.9877831,"about_ca_system_score_codex":0.00046101905,"about_ca_system_score_gemma":0.0009004694,"threshold_uncertainty_score":0.72021997},"labels":[],"label_agreement":null},{"id":"W2530831879","doi":"10.1016/j.bbi.2016.10.005","title":"Oxidative stress predicts depressive symptom changes with omega-3 fatty acid treatment in coronary artery disease patients","year":2016,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Hospital; University of Toronto; University Health Network; University of Guelph; Centre for Addiction and Mental Health; Toronto Rehabilitation Institute; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation","keywords":"Malondialdehyde; Internal medicine; Coronary artery disease; Polyunsaturated fatty acid; Oxidative stress; Medicine; Placebo; Lipid peroxidation; Gastroenterology; Depression (economics); Endocrinology; Fatty acid; Biology; Pathology; Biochemistry","score_opus":0.02173119940667533,"score_gpt":0.25138119669447007,"score_spread":0.22964999728779473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2530831879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978705,0.00008539807,0.000018434734,0.0003400684,0.00007055013,0.00082876504,0.00063369947,0.00006187516,0.00009071585],"genre_scores_gemma":[0.9989964,0.00013185343,0.0000123437585,0.0002526411,0.000013713893,0.00032888702,0.00004234727,0.00002283271,0.00019897956],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99856275,0.00028686677,0.00013958299,0.0004350425,0.00022153436,0.0003542253],"domain_scores_gemma":[0.9990122,0.0002875814,0.000090442096,0.00037392747,0.00003152649,0.00020436788],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000443502,0.00026576512,0.00020798198,0.0001197765,0.00019332346,0.000040801486,0.00020237193,0.00006124682,0.00004578693],"category_scores_gemma":[0.00014863114,0.00016425132,0.00003632168,0.00015355456,0.00034118386,0.00031818505,0.000114778966,0.00010571118,0.0000076097917],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050648086,0.0016584515,0.8330775,0.000013124081,0.000008811174,0.00012027766,0.0010308555,2.8611362e-7,0.1157033,0.00002164353,0.000037379406,0.047821887],"study_design_scores_gemma":[0.0038985366,0.0006950485,0.8878175,0.00011089453,0.000022036536,0.0000052293844,0.00020017543,0.0000018294453,0.106938146,0.000024360475,0.000064628155,0.00022162168],"about_ca_topic_score_codex":0.000048858095,"about_ca_topic_score_gemma":0.00021737175,"teacher_disagreement_score":0.05473999,"about_ca_system_score_codex":0.00008206474,"about_ca_system_score_gemma":0.00005223525,"threshold_uncertainty_score":0.6697974},"labels":[],"label_agreement":null},{"id":"W2531632863","doi":"","title":"An optimized green fluorescent protein biosensor for the inhibitory neurotransmitter GABA","year":2015,"lang":"en","type":"article","venue":"URSCA Proceedings","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Inhibitory postsynaptic potential; Neurotransmitter; Biosensor; Fluorescence; Chemistry; Biochemistry; Biology; Neuroscience; Receptor; Physics","score_opus":0.04968808330773411,"score_gpt":0.2726275577400125,"score_spread":0.2229394744322784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2531632863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9803293,0.00008581594,0.00048266814,0.012667574,0.00042785972,0.0034395296,0.000030802075,0.00045631194,0.00208018],"genre_scores_gemma":[0.99343854,0.0000068622653,0.0014298112,0.0033647465,0.0004139103,0.00037969855,0.000001621621,0.00006146155,0.00090332254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983352,0.000024693634,0.00022784261,0.0005547518,0.00039143482,0.00046608478],"domain_scores_gemma":[0.9992792,0.000075874465,0.00009594321,0.00019192099,0.00013186863,0.00022516807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027516583,0.0002321413,0.00017336564,0.000087077766,0.00022777238,0.00018577611,0.0005696351,0.000089247595,0.000016979055],"category_scores_gemma":[0.0003469446,0.0001588072,0.00010916682,0.00026379552,0.000230481,0.00040761437,0.000047509526,0.00019867464,0.00004536122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005921658,0.00021540225,0.000056539768,0.00006852546,0.0000067625137,0.000005421441,0.0022455358,0.000012682726,0.9752481,0.002085017,0.015342514,0.00412133],"study_design_scores_gemma":[0.003057374,0.0005486106,0.00023836752,0.00003660307,0.000019271278,0.000027745618,0.0007313222,0.0050250376,0.93951416,0.001126012,0.049296156,0.00037936936],"about_ca_topic_score_codex":0.000015755717,"about_ca_topic_score_gemma":0.000001921562,"teacher_disagreement_score":0.03573397,"about_ca_system_score_codex":0.000030472309,"about_ca_system_score_gemma":0.000056859306,"threshold_uncertainty_score":0.64759696},"labels":[],"label_agreement":null},{"id":"W2532166186","doi":"10.1038/srep35169","title":"Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; University of California, San Francisco; National Institutes of Health","keywords":"Tryptophan; Dioxygenase; Ternary complex; Indole test; Binding site; Chemistry; Active site; Indoleamine 2,3-dioxygenase; Biochemistry; Stereochemistry; Enzyme; Amino acid","score_opus":0.020035468327128256,"score_gpt":0.25002432385456913,"score_spread":0.22998885552744086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2532166186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966694,0.000081399885,0.0018704694,0.00009356718,0.0005676232,0.00043233053,0.000025844178,0.00005689075,0.00020243875],"genre_scores_gemma":[0.999313,0.000005159776,0.00008225206,0.000025254527,0.000012487436,0.000033161527,0.000034641187,0.000019592588,0.0004744425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979188,0.00006527421,0.00048562672,0.0008509383,0.00039402477,0.00028532452],"domain_scores_gemma":[0.99864745,0.00013983258,0.0003235705,0.00063215056,0.00012755921,0.0001294441],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056990754,0.00014635961,0.00020522339,0.00022361819,0.00023579449,0.000093174174,0.0001376883,0.00006659294,0.00009394692],"category_scores_gemma":[0.0011996095,0.00010831469,0.00010696568,0.0005893119,0.00050450634,0.0002160513,0.00004497238,0.000029812632,0.0000044434373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008968374,0.00007891496,0.00044090816,0.00003929106,0.0000051788725,0.00004865775,0.00015142087,0.0000054968937,0.9979774,0.000396774,0.0002208747,0.0006261279],"study_design_scores_gemma":[0.00028648684,0.000048402937,0.00039263963,0.00002537844,0.000010957435,0.000010227659,0.00006730959,0.00004660637,0.9937523,0.004486676,0.00072546274,0.00014757735],"about_ca_topic_score_codex":0.000010518013,"about_ca_topic_score_gemma":0.000017989867,"teacher_disagreement_score":0.004225111,"about_ca_system_score_codex":0.000023728051,"about_ca_system_score_gemma":0.000075897515,"threshold_uncertainty_score":0.44169447},"labels":[],"label_agreement":null},{"id":"W2542075442","doi":"10.1016/j.clim.2016.10.012","title":"Intraperitoneal injection of IDO-expressing dermal fibroblasts improves the allograft survival","year":2016,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Immunosuppression; Peritoneal cavity; Medicine; Immune system; Fibroblast; Transplantation; Fibroblast activation protein, alpha; Immunology; Cancer research; Infiltration (HVAC); Immune tolerance; Biology; Cancer; Internal medicine; Surgery; Cell culture","score_opus":0.046408419721423955,"score_gpt":0.3285502472565625,"score_spread":0.28214182753513856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2542075442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948891,0.00012205434,0.0006197607,0.0019120511,0.0015680029,0.0001349977,0.0000053578187,0.00007440455,0.0006742947],"genre_scores_gemma":[0.9988448,0.00017726333,0.00008356105,0.0004961397,0.00015304484,0.000009570109,5.611517e-7,0.000014827388,0.00022021063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979983,0.00062840135,0.0005526569,0.0003755596,0.00011960692,0.0003255057],"domain_scores_gemma":[0.9967011,0.0026277804,0.00021134765,0.00038380636,0.000036098612,0.000039851264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003302191,0.00013079397,0.00026267773,0.00004720417,0.00012959946,0.00001844805,0.00045642527,0.00021202881,0.00008710059],"category_scores_gemma":[0.0022768977,0.000071579576,0.00016613623,0.00015372822,0.0018943929,0.00014607451,0.00020830179,0.00026962138,0.00005263087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019761488,0.00013061457,0.0014449436,0.000003744296,0.000020345193,0.000002583989,0.000055100147,6.921705e-7,0.9190718,0.0014761866,0.00013219686,0.077464156],"study_design_scores_gemma":[0.002980071,0.0016103726,0.28656977,0.000074532414,0.000022886654,0.00008165213,0.00020488643,0.000070238624,0.69399995,0.003639878,0.010410305,0.0003354644],"about_ca_topic_score_codex":0.000014633452,"about_ca_topic_score_gemma":0.000016734253,"teacher_disagreement_score":0.28512484,"about_ca_system_score_codex":0.000010307214,"about_ca_system_score_gemma":0.000055066637,"threshold_uncertainty_score":0.6979969},"labels":[],"label_agreement":null},{"id":"W2545885512","doi":"10.1017/s204579601600072x","title":"Patterns of association of chronic medical conditions and major depression","year":2016,"lang":"en","type":"article","venue":"Epidemiology and Psychiatric Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"Social Sciences and Humanities Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Medicine; Confounding; Population; Confidence interval; Depression (economics); Demography; Odds ratio; Disease; Meta-analysis; Internal medicine; Environmental health","score_opus":0.03172611203026222,"score_gpt":0.3361397232883847,"score_spread":0.3044136112581225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2545885512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887409,0.0011279039,0.0007794875,0.008413433,0.0002896777,0.00006383752,0.000022597054,0.000010397044,0.00055173953],"genre_scores_gemma":[0.9976608,0.0015970484,0.00010423858,0.0004934444,0.000048639795,0.0000036153733,3.1465288e-7,0.0000015530028,0.00009035838],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99874663,0.00038679325,0.00027931583,0.00026033315,0.00014889296,0.0001780285],"domain_scores_gemma":[0.99542046,0.004166066,0.00026612706,0.00006980873,0.0000117634345,0.000065798085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015174038,0.000058262936,0.00018423311,0.000098846576,0.00015535242,0.0000018701131,0.00014450878,0.0001074632,0.00020319264],"category_scores_gemma":[0.004537614,0.000033187574,0.000029325047,0.00017976992,0.0004983778,0.0000865086,0.00003994363,0.00005522697,0.0000025506486],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006794233,0.000032562755,0.972867,0.000018847872,0.0000027613783,2.0400799e-7,0.0000314655,6.329784e-7,0.0050627743,0.013898664,0.00079008576,0.0072882185],"study_design_scores_gemma":[0.00077505445,0.0002548892,0.95994574,0.000058869788,0.000009057547,0.000013718808,0.000040573414,0.00015791651,0.004641871,0.033609487,0.00040888353,0.000083922874],"about_ca_topic_score_codex":0.00002948669,"about_ca_topic_score_gemma":0.000041714025,"teacher_disagreement_score":0.019710824,"about_ca_system_score_codex":0.0000071409677,"about_ca_system_score_gemma":0.00006388699,"threshold_uncertainty_score":0.5432276},"labels":[],"label_agreement":null},{"id":"W2551416739","doi":"10.1111/febs.13966","title":"Regulation of kynurenine biosynthesis during influenza virus infection","year":2016,"lang":"en","type":"editorial","venue":"FEBS Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre","funders":"Janssen Pharmaceuticals; Orionin Tutkimussäätiö; Jane ja Aatos Erkon Säätiö; Helsingin Yliopisto","keywords":"Virology; Biosynthesis; Kynurenine; Virus; Kynurenine pathway; Influenza A virus; Biology; Microbiology; Gene; Tryptophan; Biochemistry; Amino acid","score_opus":0.017032071292804988,"score_gpt":0.279003416515174,"score_spread":0.26197134522236903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2551416739","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18990919,0.000121987294,0.00018581863,0.00007474349,0.80838996,0.00014925971,0.00011945282,0.00007943625,0.000970179],"genre_scores_gemma":[0.12010862,0.0013980084,0.00004790399,0.000037440357,0.8769121,0.0000062186414,0.0000052454984,0.0000800156,0.0014044098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997742,0.00020959982,0.00056105247,0.00031661912,0.00087195827,0.00029876968],"domain_scores_gemma":[0.99803334,0.0005692127,0.0008772216,0.00024757386,0.0001657266,0.00010690959],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027729786,0.00025387216,0.00033806093,0.0004570163,0.0002452107,0.00009895286,0.00028502117,0.0005037471,0.0005650868],"category_scores_gemma":[0.0042596073,0.00019652159,0.00022563407,0.0002482545,0.000121549456,0.0003675862,0.00006400414,0.0006713255,0.00007967107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019494994,0.000048204503,0.000070457594,0.00006058758,0.000016580174,0.000008047705,0.000054011303,0.000015195321,0.6407462,0.00001777677,0.3562337,0.0025343264],"study_design_scores_gemma":[0.0010830825,0.0000984153,0.004658704,0.0004516618,0.000027429618,0.00004316386,0.000002794264,0.000004228642,0.5423914,0.0007224823,0.4502411,0.0002755325],"about_ca_topic_score_codex":0.000020956606,"about_ca_topic_score_gemma":0.000016043792,"teacher_disagreement_score":0.09835477,"about_ca_system_score_codex":0.00014128204,"about_ca_system_score_gemma":0.00018020169,"threshold_uncertainty_score":0.80139184},"labels":[],"label_agreement":null},{"id":"W2551915924","doi":"10.1016/j.neubiorev.2016.11.010","title":"Selfish brain and selfish immune system interplay: A theoretical framework for metabolic comorbidities of mood disorders","year":2016,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Immune system; Mood; Mood disorders; Neuroscience; Psychology; Medicine; Psychiatry; Immunology; Anxiety","score_opus":0.06543630169855673,"score_gpt":0.3805716340356594,"score_spread":0.31513533233710267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2551915924","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022603472,0.9901589,0.0019562792,0.00005480069,0.0015453928,0.0047687422,0.0008603387,0.00019147978,0.00023799553],"genre_scores_gemma":[0.0075339465,0.99017197,0.00061191444,0.00033281092,0.000114062364,0.0010188642,0.000012114936,0.00013691469,0.00006742798],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99339676,0.0009776866,0.002057543,0.0018316259,0.00068684533,0.0010495232],"domain_scores_gemma":[0.99647534,0.0003102298,0.0015128676,0.0012859614,0.0000626076,0.00035299943],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0012656199,0.0011219527,0.003851763,0.0004275786,0.0003660902,0.00027109447,0.0019134824,0.0005181007,0.00007059347],"category_scores_gemma":[0.004102056,0.00073922286,0.0014083548,0.001176522,0.0029366193,0.00040295147,0.0005528941,0.0006778188,0.0000350575],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013387721,0.00016785029,0.000008783875,0.007060548,5.396292e-7,0.000002857636,0.000079397105,1.1778847e-8,0.0006691556,0.1279679,0.00020702546,0.8638226],"study_design_scores_gemma":[0.00033194505,0.00036063054,0.000029388264,0.014974484,0.00029173677,0.00010522297,0.000055017725,0.000008751907,0.00016693545,0.0013190802,0.9815812,0.00077558635],"about_ca_topic_score_codex":0.000010251443,"about_ca_topic_score_gemma":0.000006343447,"teacher_disagreement_score":0.9813742,"about_ca_system_score_codex":0.000073667725,"about_ca_system_score_gemma":0.00023734813,"threshold_uncertainty_score":0.99977684},"labels":[],"label_agreement":null},{"id":"W2552975555","doi":"10.1016/j.neuint.2016.11.005","title":"Individual and interactive sex-specific effects of acute restraint and systemic IFN-γ treatment on neurochemistry","year":2016,"lang":"en","type":"article","venue":"Neurochemistry International","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Canadian Institutes of Health Research","keywords":"Monoaminergic; Monoamine neurotransmitter; Corticosterone; Amygdala; Stressor; Endocrinology; Internal medicine; Kynurenine; Cytokine; Prefrontal cortex; Hippocampus; Hypothalamus; Serotonin; Neurochemistry; Neuroscience; Psychology; Medicine; Chemistry; Hormone; Receptor; Tryptophan; Neurology; Cognition","score_opus":0.014205830411210815,"score_gpt":0.25497256492347364,"score_spread":0.24076673451226283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2552975555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99699056,0.00003640067,0.000047271184,0.0005315714,0.0002734102,0.00014814729,0.00016160251,0.00004639826,0.0017646225],"genre_scores_gemma":[0.9979963,0.00044003833,0.000019015393,0.00020921523,0.00013140809,0.000029327606,0.0000072216317,0.000019115538,0.0011484165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986347,0.00004283812,0.00022880026,0.0005923412,0.0003173459,0.00018395479],"domain_scores_gemma":[0.998789,0.00070745073,0.00015057328,0.00021465348,0.000032918007,0.00010539218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000028630055,0.00022883338,0.00018268866,0.000059021262,0.000049930706,0.000048386795,0.00026486395,0.000077370896,0.00003631264],"category_scores_gemma":[0.0002385117,0.00017077735,0.00005921086,0.00005579796,0.00023062962,0.00010178158,0.000111842724,0.00011982395,0.0000063346483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014414827,0.00013219302,0.0002766238,0.00004470757,0.000040774474,0.00009215837,0.00019242812,4.448966e-7,0.9871447,0.0001407379,0.00017415626,0.011616935],"study_design_scores_gemma":[0.0016077858,0.0002171487,0.0039704186,0.00016649523,0.000013892691,0.00038136673,0.00004797218,0.000012937627,0.9924451,0.0001157051,0.0008704516,0.00015069226],"about_ca_topic_score_codex":0.0000012540603,"about_ca_topic_score_gemma":1.3284476e-7,"teacher_disagreement_score":0.011466242,"about_ca_system_score_codex":0.000057280115,"about_ca_system_score_gemma":0.000026637817,"threshold_uncertainty_score":0.6964098},"labels":[],"label_agreement":null},{"id":"W2553027773","doi":"10.1002/pon.4316","title":"Pro‐ and anti‐inflammatory cytokine associations with major depression in cancer patients","year":2016,"lang":"en","type":"article","venue":"Psycho-Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Depression (economics); Confounding; Cancer; Cytokine; Internal medicine; Oncology; Sickness behavior; Psychological intervention; Immunology; Psychiatry","score_opus":0.02129502460622635,"score_gpt":0.3086299767620932,"score_spread":0.28733495215586685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2553027773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99419886,0.00004956478,0.00003150838,0.0017211451,0.00024930696,0.00033948838,0.000036778605,0.000042203013,0.0033311713],"genre_scores_gemma":[0.9987185,0.00016394735,0.0000680367,0.00067365373,0.00004338157,0.00010871412,0.0000014337155,0.000014974008,0.00020735167],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99893117,0.00012627243,0.00017548075,0.00035787243,0.00014533219,0.00026384558],"domain_scores_gemma":[0.9994137,0.00022918452,0.00013093968,0.00012701926,0.000029303445,0.000069808804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008665121,0.000108388034,0.00016282558,0.00010085304,0.00007785099,0.000010584049,0.00012041095,0.00011063755,0.000097058146],"category_scores_gemma":[0.00016919097,0.00006751906,0.000016627388,0.00017259552,0.00012689474,0.00014618493,0.000037634974,0.000101297446,0.000024995183],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013471204,0.000372012,0.7735596,0.000008618729,0.000004856642,0.000009622211,0.00080305367,0.0000012348053,0.19693734,0.000110360714,0.0009885824,0.027070062],"study_design_scores_gemma":[0.005028922,0.00022993497,0.9454886,0.000053037238,0.0000054823504,0.000003615083,0.00007095739,0.000007647914,0.034418747,0.00026609725,0.014262037,0.00016492658],"about_ca_topic_score_codex":0.00002475101,"about_ca_topic_score_gemma":0.00038003534,"teacher_disagreement_score":0.17192905,"about_ca_system_score_codex":0.00013470779,"about_ca_system_score_gemma":0.000081489045,"threshold_uncertainty_score":0.27533475},"labels":[],"label_agreement":null},{"id":"W2555368951","doi":"10.1016/j.neuroscience.2016.11.003","title":"Streptozotocin induced oxidative stress, innate immune system responses and behavioral abnormalities in male mice","year":2016,"lang":"en","type":"article","venue":"Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Zanjan University of Medical Sciences","keywords":"Innate immune system; Hippocampus; Neurodegeneration; Streptozotocin; Oxidative stress; Inflammation; Endocrinology; Internal medicine; Medicine; Receptor; Diabetes mellitus; Disease","score_opus":0.04713923817407971,"score_gpt":0.2940535040886201,"score_spread":0.24691426591454035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2555368951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979999,0.0000406136,0.000021858783,0.00033714125,0.0003281364,0.0003713663,0.00008544037,0.00010953321,0.00070600735],"genre_scores_gemma":[0.99837446,0.000043779575,0.000023321174,0.00026561297,0.000014772616,0.0000501215,2.8803922e-7,0.000016660844,0.001210983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99765563,0.000376502,0.00032423734,0.000747039,0.00038638661,0.0005101829],"domain_scores_gemma":[0.99903333,0.00036253274,0.00013903088,0.00032472968,0.000028188555,0.00011218739],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002610883,0.00021411985,0.00020822305,0.0002376916,0.00020517988,0.00011995619,0.0005059029,0.00006955982,0.00002334872],"category_scores_gemma":[0.00070759485,0.00015843194,0.00003669142,0.0005974483,0.00062865607,0.0007713867,0.0002343256,0.00016447109,0.000020883339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007816729,0.00007819595,0.012981027,0.000019077745,1.8045166e-7,0.00009934617,0.00038912418,0.0000010480576,0.9830604,0.0017745001,0.000010548671,0.0015083557],"study_design_scores_gemma":[0.00068346405,0.0002220378,0.13897498,0.00012825805,0.0000017086311,0.0000820012,0.00071330374,0.000045328798,0.85874337,0.000044236916,0.00014018442,0.000221123],"about_ca_topic_score_codex":0.0001531848,"about_ca_topic_score_gemma":0.000054790264,"teacher_disagreement_score":0.12599395,"about_ca_system_score_codex":0.00006024284,"about_ca_system_score_gemma":0.000087023494,"threshold_uncertainty_score":0.6460667},"labels":[],"label_agreement":null},{"id":"W2556128087","doi":"10.1002/ar.23517","title":"Ionized calcium‐binding adaptor molecule 1 positive macrophages and HO‐1 up‐regulation in intestinal muscularis resident macrophages","year":2016,"lang":"en","type":"article","venue":"The Anatomical Record","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"","keywords":"Chemistry; Calcium-binding protein; Macrophage; Calcium; Pathology; Cell biology; Internal medicine; Medicine; Biology; Biochemistry; In vitro","score_opus":0.02329459952598069,"score_gpt":0.27310892713076895,"score_spread":0.24981432760478828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2556128087","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953808,0.000105155916,0.0014310342,0.0022496928,0.00014082686,0.00030202323,0.000018094832,0.00006155858,0.0003107755],"genre_scores_gemma":[0.9984029,0.000118924894,0.00018302893,0.00036696586,0.000048993585,0.000020434616,0.0000014848747,0.000024975581,0.0008323088],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99826217,0.00034976247,0.0002788209,0.00048120643,0.00025288633,0.0003751613],"domain_scores_gemma":[0.9986292,0.00087934255,0.00010248335,0.00025299622,0.000028281544,0.000107660075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024091892,0.00019356761,0.00021068759,0.00013400191,0.0001669486,0.000079542144,0.00029173185,0.00008042553,0.00014780983],"category_scores_gemma":[0.0010640032,0.0001172273,0.000075557204,0.00030339116,0.00033097868,0.00021545266,0.00017567065,0.0001935786,0.00007317937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033984196,0.00003565242,0.0011763378,0.000007675019,0.000005961779,0.000048453803,0.000235165,0.0000010816767,0.9715514,0.0023203802,0.00024056403,0.024037447],"study_design_scores_gemma":[0.0019367638,0.00012115209,0.08911168,0.0001555953,0.000012882369,0.000040922103,0.00019037705,0.0007950227,0.90092635,0.006245303,0.00016704926,0.00029691146],"about_ca_topic_score_codex":0.00018853656,"about_ca_topic_score_gemma":0.00007447814,"teacher_disagreement_score":0.08793534,"about_ca_system_score_codex":0.00009959168,"about_ca_system_score_gemma":0.000037816102,"threshold_uncertainty_score":0.47803906},"labels":[],"label_agreement":null},{"id":"W2557277616","doi":"10.1002/gps.4645","title":"Depression with inflammation: longitudinal analysis of a proposed depressive subtype in community dwelling older adults","year":2016,"lang":"en","type":"article","venue":"International Journal of Geriatric Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"H. Lundbeck A/S; Eli Lilly and Company; American Heart Association","keywords":"Depression (economics); Longitudinal study; Inflammation; Gerontology; Psychology; Depressive symptoms; Medicine; Internal medicine; Psychiatry; Clinical psychology; Cognition; Pathology","score_opus":0.011403059196652415,"score_gpt":0.2652729095266657,"score_spread":0.2538698503300133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2557277616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940315,0.00017413338,0.004036575,0.0007140126,0.00065951934,0.00011277171,0.000013117921,0.000009799271,0.00024858819],"genre_scores_gemma":[0.998887,0.00008916976,0.00075420045,0.000054920736,0.00018242956,0.0000021701928,0.0000017398398,0.00001059954,0.000017757995],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99813527,0.00023486836,0.0006557602,0.00017128962,0.0006546586,0.00014817153],"domain_scores_gemma":[0.99801326,0.0003525008,0.0010344516,0.0001955539,0.00033905506,0.00006518523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003061589,0.00013386553,0.00028182776,0.0010247704,0.000056594316,0.00003052238,0.0006578984,0.00006529411,0.00011674495],"category_scores_gemma":[0.00025069262,0.00008287488,0.00016938295,0.0008950176,0.00008490728,0.00039930758,0.00006425413,0.00025122345,0.0000029572268],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028905743,0.0006087506,0.9655689,0.00003264657,0.00038750377,0.00005047043,0.0009905878,0.0012381392,0.017363656,0.00034834878,0.00007433409,0.01044606],"study_design_scores_gemma":[0.0051948274,0.00020881875,0.9652386,0.0006928387,0.00014788244,0.000094864816,0.0003701285,0.0003388942,0.026681557,0.00082353526,0.000024620935,0.00018345208],"about_ca_topic_score_codex":0.00005146438,"about_ca_topic_score_gemma":0.00024645653,"teacher_disagreement_score":0.0102626085,"about_ca_system_score_codex":0.00006071808,"about_ca_system_score_gemma":0.00017468481,"threshold_uncertainty_score":0.33795395},"labels":[],"label_agreement":null},{"id":"W2557456288","doi":"10.1007/s12325-016-0455-x","title":"Sirukumab: A Potential Treatment for Mood Disorders?","year":2016,"lang":"en","type":"review","venue":"Advances in Therapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; University Health Network","funders":"Pfizer; H. Lundbeck A/S; Purdue University; AstraZeneca; Allergan; Eli Lilly and Company","keywords":"Medicine; Mood; Anxiety; Mood disorders; Cognition; Anhedonia; Disease; Major depressive disorder; Research Domain Criteria; Bioinformatics; Psychiatry; Clinical psychology; Immunology; Internal medicine","score_opus":0.04639387100269654,"score_gpt":0.3714001226772261,"score_spread":0.32500625167452957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2557456288","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000008951454,0.9944083,0.00062355003,0.00007498603,0.00073061057,0.0020382053,0.0001444684,0.00008238422,0.0018885349],"genre_scores_gemma":[0.00013234072,0.9973539,0.00013267109,0.00009340927,0.00019772151,0.001213107,0.000013304003,0.00008441418,0.00077911234],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99798405,0.00016118767,0.00041966746,0.0007792288,0.00016796749,0.00048789996],"domain_scores_gemma":[0.99867445,0.0005942245,0.00024419726,0.00042040722,0.000008619356,0.000058114256],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006620263,0.00049816346,0.0009791711,0.00018281832,0.00009907478,0.00003680004,0.0004951681,0.00017241502,0.000102184415],"category_scores_gemma":[0.000072336756,0.00030218167,0.0005794079,0.000261298,0.00014441178,0.0002651842,0.000026079933,0.00010474676,0.00006963353],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057691785,0.00020930766,4.205684e-7,0.00043797895,0.000013050555,0.0000021431158,0.000041501185,0.0000020399762,0.000022539904,0.0010798974,0.000017827195,0.9981156],"study_design_scores_gemma":[0.0020103746,0.00041110037,4.5855705e-7,0.0011378527,0.000012438075,0.0000059470444,0.000009399224,0.0000026858143,0.00013923345,0.007905048,0.98798245,0.0003830255],"about_ca_topic_score_codex":0.000002609446,"about_ca_topic_score_gemma":0.0000411525,"teacher_disagreement_score":0.9977326,"about_ca_system_score_codex":0.0001276002,"about_ca_system_score_gemma":0.00010510716,"threshold_uncertainty_score":0.999943},"labels":[],"label_agreement":null},{"id":"W2557804582","doi":"10.5455/bcp.20161123044657","title":"Neuroinflammation in Schizophrenia: A Critical Review and The Future","year":2016,"lang":"en","type":"review","venue":"Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Neuroinflammation; Schizophrenia (object-oriented programming); Neuroscience; Neurodegeneration; Genetic predisposition; Psychology; Psychiatry; Population; Medicine; Inflammation; Immunology; Disease; Internal medicine","score_opus":0.06986699706652899,"score_gpt":0.4430976735379742,"score_spread":0.3732306764714452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2557804582","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000043072196,0.93665785,0.000007833016,0.052244455,0.0045201285,0.003179692,0.00009872272,0.000105413965,0.0031428349],"genre_scores_gemma":[0.00010911025,0.97939175,0.00015397774,0.017534424,0.0017504512,0.0005157521,0.000008488525,0.00012541535,0.00041064777],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98157656,0.009244993,0.005709174,0.0019684175,0.000564883,0.000935978],"domain_scores_gemma":[0.96761745,0.0287444,0.0020567738,0.001052569,0.00014313628,0.00038566996],"candidate_categories":["metaresearch","metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00503422,0.0010170472,0.006223217,0.00036537094,0.0001739493,0.000042428375,0.0018086291,0.0012253283,0.0022200425],"category_scores_gemma":[0.013574326,0.000592974,0.0017177591,0.00076242787,0.0041005425,0.000081111815,0.000550753,0.003235534,0.00090577273],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016599463,0.00041018764,0.0000024825702,0.019359585,0.00009323483,0.00010193387,0.000020046522,9.3397055e-8,0.0000069605717,0.008998058,0.06858298,0.90076447],"study_design_scores_gemma":[0.010544705,0.00021074885,0.000017638806,0.008955884,0.00084816094,0.00018815164,0.000007408834,0.000004244548,0.000002750171,0.0013322325,0.97731155,0.000576547],"about_ca_topic_score_codex":0.000004496219,"about_ca_topic_score_gemma":0.0000034189686,"teacher_disagreement_score":0.90872854,"about_ca_system_score_codex":0.0000361791,"about_ca_system_score_gemma":0.00037438574,"threshold_uncertainty_score":0.99987215},"labels":[],"label_agreement":null},{"id":"W2561962108","doi":"","title":"The Role of Prostaglandin H Synthase (PHS) Bioactivation and Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)-Mediated Protection in Endogenous and Methamphetamine-initiated Neurotoxicity","year":2012,"lang":"en","type":"dissertation","venue":"TSpace","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Endogeny; Methamphetamine; Neurotoxicity; Chemistry; Pharmacology; Biochemistry; Medicine; Toxicity","score_opus":0.04271434111672455,"score_gpt":0.28375189221008074,"score_spread":0.24103755109335617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2561962108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99572885,0.0005691024,0.0000022799838,0.0000934228,0.0002104583,0.002119842,0.00010652727,0.00011192218,0.0010575657],"genre_scores_gemma":[0.99899465,0.00046698496,0.000006731699,0.000020788735,0.000020986558,0.000089351044,0.000085367436,0.00007042166,0.00024473143],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99791324,0.00038321535,0.00042223695,0.00053679134,0.00033920308,0.00040533225],"domain_scores_gemma":[0.9985426,0.00048848824,0.0005334974,0.000258178,0.000060143986,0.00011705829],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016081677,0.00037506787,0.00038208097,0.00027607076,0.00025515113,0.00008395775,0.0001647031,0.0003798002,0.00007482614],"category_scores_gemma":[0.0012268949,0.00029763984,0.00005956205,0.00052269053,0.00018023248,0.00025206155,0.000043031243,0.0005516209,0.000009845475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045366975,0.00015310966,0.00044594036,0.00011817721,0.000017702816,0.0000041806684,0.009307357,6.887841e-7,0.9834272,0.00006533682,0.0000032838118,0.006003341],"study_design_scores_gemma":[0.0015933813,0.0003276771,0.081873626,0.00013819695,0.00002753222,0.000027697843,0.0057158605,0.00052928366,0.90818876,0.00015259343,0.00091947376,0.00050588633],"about_ca_topic_score_codex":0.0005472645,"about_ca_topic_score_gemma":0.00034880734,"teacher_disagreement_score":0.081427686,"about_ca_system_score_codex":0.00005626667,"about_ca_system_score_gemma":0.00006625885,"threshold_uncertainty_score":0.99994755},"labels":[],"label_agreement":null},{"id":"W2562179245","doi":"10.1139/cjpp-2016-0598","title":"Olanzapine alleviates oxidative stress in the liver of socially isolated rats","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Olanzapine; Superoxide dismutase; Oxidative stress; Malondialdehyde; Catalase; Endocrinology; Chemistry; Antioxidant; Internal medicine; Pharmacology; Biochemistry; Medicine; Schizophrenia (object-oriented programming); Psychiatry","score_opus":0.02381274947280796,"score_gpt":0.27408168642327624,"score_spread":0.25026893695046826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2562179245","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961307,0.0005231453,0.000008967855,0.0028426414,0.0002475404,0.000081266764,0.000030963893,0.0000014425035,0.0001333243],"genre_scores_gemma":[0.99715596,0.0005394521,0.0000066312127,0.0021723174,0.00008790238,0.0000016957754,4.3307105e-7,0.000004142105,0.000031450338],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897015,0.0004566078,0.00020524098,0.00010859995,0.000041663432,0.00021776312],"domain_scores_gemma":[0.9991146,0.0005104635,0.0001784746,0.000045084704,0.00004815559,0.00010325083],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001618129,0.00008093364,0.00018932208,0.00013285395,0.000071602335,0.0000035154696,0.0002655756,0.000074501804,0.0008731712],"category_scores_gemma":[0.00009436089,0.00004572921,0.000041384083,0.00012010259,0.0005084767,0.00008794261,0.000011678144,0.00017306802,0.000004660146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011390619,0.000030752173,0.00043949083,0.00001200247,0.000017737288,0.00007584651,0.0013885944,0.00000461334,0.9941124,0.0006587417,0.0019071123,0.0012388385],"study_design_scores_gemma":[0.001561911,0.0004590652,0.02159077,0.00002659263,0.000017049055,0.000054625016,0.0002268674,0.000015874039,0.96959937,0.004531287,0.0018198695,0.00009670067],"about_ca_topic_score_codex":0.00019411866,"about_ca_topic_score_gemma":0.0021241987,"teacher_disagreement_score":0.024512976,"about_ca_system_score_codex":0.000016347174,"about_ca_system_score_gemma":0.00034407043,"threshold_uncertainty_score":0.95606124},"labels":[],"label_agreement":null},{"id":"W2562896472","doi":"10.1007/s00213-016-4499-z","title":"Retraction note to: Chronic fluoxetine increases cytosolic phospholipase A2 activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat","year":2016,"lang":"en","type":"retraction","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Arachidonic acid; Phospholipase A2; Fluoxetine; Cytosol; Pharmacology; Arachidonic acid metabolism; Phospholipase; Chemistry; Endocrinology; Internal medicine; Medicine; Biochemistry; Serotonin; Enzyme; Receptor","score_opus":0.014076141793659352,"score_gpt":0.3125877882942287,"score_spread":0.2985116465005693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2562896472","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97815317,0.0020065876,0.00002754662,0.0055301297,0.01071404,0.0017963287,0.00021545762,0.00010141074,0.001455357],"genre_scores_gemma":[0.9839787,0.007539116,0.000014504559,0.003414741,0.0010535524,0.00021849651,0.00001097903,0.00011136463,0.0036585857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99554485,0.0010496528,0.0006871745,0.0013003764,0.0006071328,0.00081081607],"domain_scores_gemma":[0.9968453,0.0013488746,0.000794615,0.00070395716,0.000066776716,0.00024050023],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00061041047,0.0007060463,0.0009375639,0.00049854576,0.00019870022,0.000046413512,0.0007738667,0.0010686971,0.0008884234],"category_scores_gemma":[0.0009566251,0.0004971301,0.00031171096,0.0010474392,0.00053991517,0.00029224055,0.00019291953,0.0018890437,0.00011817845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026523587,0.000508736,0.00013358306,0.00021812315,0.000022555098,0.000025928673,0.0001270304,0.0000092804075,0.93880534,0.000024192894,0.027973616,0.029499276],"study_design_scores_gemma":[0.008266787,0.00045376245,0.0103464,0.00036796133,0.000084426356,0.0002082686,0.0000070648516,0.00006722016,0.7338111,0.00015268213,0.2455396,0.00069470756],"about_ca_topic_score_codex":0.00035853707,"about_ca_topic_score_gemma":0.0004408217,"teacher_disagreement_score":0.217566,"about_ca_system_score_codex":0.0005790916,"about_ca_system_score_gemma":0.0004856243,"threshold_uncertainty_score":0.99974805},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"other","about_ca_system":false,"about_ca_topic":false,"confidence":"high"},{"model":"gpt","categories":[],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"agree"},{"id":"W2567498147","doi":"10.1038/tp.2016.148","title":"Insights into psychosis risk from leukocyte microRNA expression","year":2016,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Center for Gastrointestinal Biology and Disease, School of Medicine, University of North Carolina at Chapel Hill; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; International Mental Health Research Organization; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression; Gerber Foundation","keywords":"Psychosis; microRNA; Biomarker; Immune system; Schizophrenia (object-oriented programming); Small RNA; Bioinformatics; Biology; Medicine; Oncology; Psychology; Immunology; Psychiatry; Genetics; Gene","score_opus":0.016553975238561516,"score_gpt":0.25493783185073693,"score_spread":0.23838385661217543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2567498147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97683805,0.0009559806,0.0118231,0.0056003826,0.001303216,0.00018119672,0.00007480487,0.00016079505,0.0030624848],"genre_scores_gemma":[0.99266666,0.00021848068,0.005421605,0.0011483,0.0003291591,0.000016503365,0.000009155819,0.000028562366,0.00016157348],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984402,0.00013009697,0.00028665023,0.00057758525,0.0003571142,0.00020832045],"domain_scores_gemma":[0.9991581,0.00028858832,0.000111666144,0.00030606525,0.00001845393,0.00011711792],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000038120885,0.00019799916,0.00013943888,0.0001041524,0.00024306675,0.000030405627,0.00031681632,0.00011709837,0.0006605442],"category_scores_gemma":[0.00003972852,0.00013454408,0.00014238637,0.00020642504,0.00013118141,0.0003175387,0.000014620495,0.00014084316,0.00053242134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021085364,0.00015958468,0.008826157,0.000006794437,0.000009477563,8.3446844e-7,0.00042354708,0.000009809594,0.96562535,0.0052523497,0.004768705,0.01470653],"study_design_scores_gemma":[0.0039196606,0.00006476676,0.11111382,0.0001676789,0.000017924005,0.0000017424293,0.000059806054,0.00007049825,0.47934824,0.37100196,0.033701416,0.000532497],"about_ca_topic_score_codex":0.000042062013,"about_ca_topic_score_gemma":0.00014051625,"teacher_disagreement_score":0.48627713,"about_ca_system_score_codex":0.00001442892,"about_ca_system_score_gemma":0.00006127031,"threshold_uncertainty_score":0.72324955},"labels":[],"label_agreement":null},{"id":"W2568270526","doi":"10.1139/apnm-2016-0530","title":"Dose-dependent decrease in mortality with no cognitive or muscle function improvements due to dietary EGCG supplementation in aged mice","year":2017,"lang":"en","type":"article","venue":"Applied Physiology Nutrition and Metabolism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Endocrinology; Affect (linguistics); Internal medicine; Cognition; Preference test; Skeletal muscle; Medicine; Treadmill; Oxidative stress; Psychology; Preference; Neuroscience","score_opus":0.03085379511197331,"score_gpt":0.2934607204793311,"score_spread":0.26260692536735775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2568270526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99776286,0.000026131684,0.000039899824,0.000132246,0.00015010721,0.001215358,0.00008117934,0.000027589045,0.00056460284],"genre_scores_gemma":[0.99614185,0.00016572734,0.00013709269,0.002724247,0.00007278996,0.00062202965,0.00008703013,0.0000148367435,0.000034405497],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986686,0.00011021439,0.00022620951,0.0005630238,0.00014554268,0.0002864199],"domain_scores_gemma":[0.99942905,0.000089098554,0.00013133329,0.00020406471,0.00002707824,0.000119403936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013671354,0.00018111007,0.00026472393,0.00013536547,0.00022040386,0.000047915375,0.00013445075,0.000075085336,0.00012500212],"category_scores_gemma":[0.0001114425,0.00015304676,0.000024511894,0.0001260758,0.00013865791,0.00024028769,0.00007674386,0.00016017421,0.00002832903],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021564236,0.00074032496,0.0002750793,0.00004494685,0.0000113326805,0.000017774128,0.00030355368,0.0000015682313,0.9867778,0.00056314876,0.00007709902,0.0090309465],"study_design_scores_gemma":[0.011087027,0.000077331795,0.9223163,0.00003283505,0.000022334998,0.0000017284488,0.0005523115,0.000015367517,0.06301755,0.0022351674,0.00044129798,0.00020073056],"about_ca_topic_score_codex":0.00039390998,"about_ca_topic_score_gemma":0.0012450522,"teacher_disagreement_score":0.92376024,"about_ca_system_score_codex":0.000017325856,"about_ca_system_score_gemma":0.000031334417,"threshold_uncertainty_score":0.6241066},"labels":[],"label_agreement":null},{"id":"W2572063635","doi":"10.1007/s00005-016-0434-6","title":"An Association Between Functional Polymorphisms of the Interleukin 1 Gene Complex and Schizophrenia Using Transmission Disequilibrium Test","year":2016,"lang":"en","type":"article","venue":"Archivum Immunologiae et Therapiae Experimentalis","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu","keywords":"Haplotype; Transmission disequilibrium test; Genetics; Schizophrenia (object-oriented programming); Biology; Disequilibrium; Linkage disequilibrium; Allele; Genetic association; Gene; Single-nucleotide polymorphism; Genotype; Psychiatry; Medicine; Surgery","score_opus":0.04556725078930026,"score_gpt":0.285450340209358,"score_spread":0.23988308942005773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2572063635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967509,0.00028931996,0.000903705,0.0012342457,0.00015457372,0.00025296348,0.00017232134,0.00007770629,0.00016428914],"genre_scores_gemma":[0.9988432,0.00008859773,0.0005033798,0.00036908124,0.000048314196,0.000013619533,0.000014845938,0.000029849603,0.00008913935],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982084,0.00048452543,0.0003084952,0.0004012046,0.00030396847,0.00029340942],"domain_scores_gemma":[0.99875325,0.0005891006,0.00022887046,0.00035149397,0.000015424745,0.00006187944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017217801,0.00021457365,0.00021520913,0.00009073345,0.00022794504,0.000046104495,0.00041680725,0.00008356628,0.00026772983],"category_scores_gemma":[0.00010431316,0.000127262,0.00011673409,0.00016301981,0.0004609459,0.00034521075,0.0001434684,0.0001361899,0.000004824702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017287522,0.00016271508,0.0085897995,0.0000026218427,0.00003160988,5.248852e-7,0.0008147177,0.0000011456921,0.97996795,0.0003588573,0.00003157157,0.009865614],"study_design_scores_gemma":[0.001279018,0.00022188252,0.19719574,0.000039027876,0.000007970995,0.0000069888856,0.00009527318,0.00004821334,0.80010074,0.00070653704,0.00014454035,0.00015404078],"about_ca_topic_score_codex":0.000055822806,"about_ca_topic_score_gemma":0.0000018429297,"teacher_disagreement_score":0.18860593,"about_ca_system_score_codex":0.00010133418,"about_ca_system_score_gemma":0.00005165652,"threshold_uncertainty_score":0.51895934},"labels":[],"label_agreement":null},{"id":"W2575808097","doi":"10.1098/rstb.2016.0160","title":"Tumour necrosis factor-mediated homeostatic synaptic plasticity in behavioural models: testing a role in maternal immune activation","year":2017,"lang":"en","type":"article","venue":"Philosophical Transactions of the Royal Society B Biological Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Proinflammatory cytokine; Homeostatic plasticity; Neuroscience; Neuroinflammation; Synaptic plasticity; Metaplasticity; Synaptic scaling; Neuroplasticity; Glutamate receptor; Tumor necrosis factor alpha; Biology; Psychology; Inflammation; Immunology; Receptor","score_opus":0.1216724936720387,"score_gpt":0.28550348282354204,"score_spread":0.16383098915150335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2575808097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957379,0.000014093565,0.00089402683,0.0027193727,0.00008088042,0.00025986804,0.0000415505,0.000038519956,0.00021377104],"genre_scores_gemma":[0.9995391,0.000015296795,0.00028430836,0.0001083094,0.000015048352,0.000027518916,4.6723713e-7,0.000005730567,0.0000042667953],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981715,0.00017520528,0.00040721564,0.00045343908,0.00037568988,0.00041693606],"domain_scores_gemma":[0.99861175,0.00087174895,0.00023881078,0.00017832921,0.000026194348,0.00007315757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027059813,0.00018272208,0.0002758099,0.000046553592,0.0008432126,0.00011357864,0.0010977957,0.00016272749,0.000046374644],"category_scores_gemma":[0.0011601228,0.00011241692,0.00021114663,0.0004586057,0.0017752612,0.00032914398,0.00008377756,0.00048149505,0.0000032357252],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016253973,0.0012826715,0.18963,0.00004591812,0.000018329545,0.000004716287,0.0010783627,0.037554976,0.7650663,0.0017547661,9.953467e-7,0.0034003803],"study_design_scores_gemma":[0.0005882328,0.00020317984,0.7179219,0.00010092342,0.0000050839176,0.0000020668901,0.00015101364,0.20579925,0.028442662,0.04658715,2.1719926e-7,0.00019833299],"about_ca_topic_score_codex":0.0013424094,"about_ca_topic_score_gemma":0.00004168181,"teacher_disagreement_score":0.7366237,"about_ca_system_score_codex":0.000073124014,"about_ca_system_score_gemma":0.000052680996,"threshold_uncertainty_score":0.6541024},"labels":[],"label_agreement":null},{"id":"W2576625712","doi":"","title":"The multiple effects of mood stabilizers and antidepressants on neuroprotection:translating basic findings into clinical practice","year":2005,"lang":"en","type":"article","venue":"Acta Neurobiologiae Experimentalis","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Neuroprotection; Mood; Clinical Practice; Psychology; Psychotherapist; Medicine; Neuroscience; Psychiatry; Physical therapy","score_opus":0.025420894633654687,"score_gpt":0.32180612572208794,"score_spread":0.29638523108843323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2576625712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99584377,0.00017142908,0.000010341919,0.0014343539,0.00050213886,0.0006796403,0.0000071102863,0.00010481122,0.00124642],"genre_scores_gemma":[0.9979217,0.0003507935,0.0002643886,0.0012821343,0.00007461565,0.000044332784,0.0000015356115,0.000028825081,0.000031641033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99751824,0.0007974616,0.00046836847,0.00066448183,0.00021723646,0.0003342213],"domain_scores_gemma":[0.9930332,0.0062390584,0.00022016422,0.000395753,0.00002241667,0.00008943203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033196062,0.0002395494,0.00023998406,0.000053600324,0.00044419942,0.000073412484,0.0003627874,0.000107855376,0.000014465911],"category_scores_gemma":[0.0074001355,0.00017045402,0.0001102298,0.00019996673,0.0006091531,0.00033691042,0.00015468008,0.00037916467,0.00000979438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028211332,0.0003088355,0.0010286017,0.000017406717,0.0000105135,0.0000046340238,0.000681501,0.000008043729,0.99071944,0.000114029,0.0003154829,0.0065094093],"study_design_scores_gemma":[0.0013715312,0.0008430493,0.0038213676,0.000022696593,0.000008572564,0.00002850742,0.0004005245,0.00017212064,0.9883303,0.000020369389,0.004803578,0.0001773531],"about_ca_topic_score_codex":0.000029339712,"about_ca_topic_score_gemma":0.000011287667,"teacher_disagreement_score":0.007068175,"about_ca_system_score_codex":0.000022029686,"about_ca_system_score_gemma":0.00001956233,"threshold_uncertainty_score":0.8859188},"labels":[],"label_agreement":null},{"id":"W2580142118","doi":"10.1016/j.neuroscience.2017.01.033","title":"Prenatal maternal immune activation and brain development with relevance to psychiatric disorders","year":2017,"lang":"en","type":"article","venue":"Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Centre for Addiction and Mental Health Foundation","keywords":"Schizophrenia (object-oriented programming); Psychiatry; Offspring; Bipolar disorder; Autism; Medicine; Animal studies; Epidemiology; Pathological; Epidemiology of child psychiatric disorders; Psychology; Psychosis; Pregnancy; Pathology; Cognition; Biology; Internal medicine","score_opus":0.014923999805421584,"score_gpt":0.25697275674444126,"score_spread":0.24204875693901967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2580142118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99143344,0.000008047186,0.002472335,0.0041554365,0.00033316485,0.00030632183,0.0000028284494,0.000068489884,0.0012199576],"genre_scores_gemma":[0.9957816,0.000022575317,0.0010222809,0.002345569,0.000020507763,0.000026367825,1.9842226e-7,0.00001596938,0.00076493074],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983901,0.000032116575,0.0001521985,0.0006707197,0.00039377887,0.00036111122],"domain_scores_gemma":[0.99917555,0.00007994692,0.0001455968,0.00044903936,0.000013712483,0.00013614284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010800478,0.00016257692,0.00010596215,0.0001040385,0.0010701161,0.00038435764,0.0007222163,0.000027970656,0.000006464936],"category_scores_gemma":[0.0009900776,0.00013284547,0.000016459986,0.00022916145,0.00032057872,0.00069669157,0.0002193853,0.00012398971,0.000019322322],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002196844,0.00014146474,0.033408113,0.000060027745,9.850387e-7,0.000013963193,0.0006134751,0.00013084321,0.8840597,0.0016606415,0.00023332745,0.07945773],"study_design_scores_gemma":[0.00043037767,0.00013516344,0.7304771,0.000035211357,7.522394e-7,0.000018033696,0.000011947357,0.00016478972,0.2622193,0.00017727642,0.006130778,0.00019923579],"about_ca_topic_score_codex":0.000025978023,"about_ca_topic_score_gemma":0.00003734769,"teacher_disagreement_score":0.697069,"about_ca_system_score_codex":0.000018121627,"about_ca_system_score_gemma":0.00006777518,"threshold_uncertainty_score":0.8230576},"labels":[],"label_agreement":null},{"id":"W2582369321","doi":"10.1038/srep41382","title":"Behavioural Effects of Using Sulfasalazine to Inhibit Glutamate Released by Cancer Cells: A Novel target for Cancer-Induced Depression","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University","funders":"Canadian Institutes of Health Research; Cure Brain Cancer Foundation; McMaster University","keywords":"Anhedonia; Pharmacology; Medicine; Cancer; Sulfasalazine; Behavioural despair test; Fluoxetine; Antidepressant; Anxiolytic; Immunology; Internal medicine; Receptor; Disease","score_opus":0.04692904044075131,"score_gpt":0.31863726937884307,"score_spread":0.27170822893809177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2582369321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98976344,0.00009416112,0.0005156537,0.00014155384,0.0081508085,0.0011484132,0.00008948663,0.000052593303,0.000043884243],"genre_scores_gemma":[0.9981898,0.0000028259428,0.0006586032,0.00008747018,0.000048057478,0.00015074859,0.000008011597,0.000036368318,0.00081811514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973553,0.00003224937,0.00046335033,0.0010957118,0.0005422138,0.00051120436],"domain_scores_gemma":[0.99771875,0.000074147196,0.0007782783,0.0010669967,0.00014242386,0.00021941052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039684094,0.00021777475,0.0003057656,0.00014216863,0.0009234891,0.0003414809,0.00039215514,0.000090979265,0.00003443596],"category_scores_gemma":[0.0009477116,0.00019337496,0.00012964502,0.00026024782,0.00023846947,0.00033329014,0.00018546266,0.00009930285,0.0000023813202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004057589,0.00013594491,0.0041492726,0.0001098217,0.000003545422,0.000039218536,0.00014223394,0.000102908605,0.99019533,0.0000032795504,0.003546856,0.0015310078],"study_design_scores_gemma":[0.0006210676,0.000049250404,0.003374068,0.0002542261,0.000019990779,0.000010988803,0.000009687902,0.00080757355,0.9928694,0.00011356915,0.0016319291,0.00023828603],"about_ca_topic_score_codex":0.0015311976,"about_ca_topic_score_gemma":0.00016662985,"teacher_disagreement_score":0.008426354,"about_ca_system_score_codex":0.00008320241,"about_ca_system_score_gemma":0.0002385204,"threshold_uncertainty_score":0.78856015},"labels":[],"label_agreement":null},{"id":"W2582903515","doi":"10.1111/acps.12698","title":"Peripheral cytokine and chemokine alterations in depression: a meta‐analysis of 82 studies","year":2017,"lang":"en","type":"review","venue":"Acta Psychiatrica Scandinavica","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1426,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Major depressive disorder; Cytokine; Meta-analysis; Chemokine; Internal medicine; Medicine; Chemokine receptor; Tumor necrosis factor alpha; Oncology; Receptor; Immunology; Amygdala","score_opus":0.21218396012287802,"score_gpt":0.43032163433559134,"score_spread":0.21813767421271332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2582903515","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017906388,0.99689966,0.000005004913,0.00032347592,0.0002013339,0.00063943653,0.00021943747,0.00003335116,0.0014992291],"genre_scores_gemma":[0.019703517,0.9791806,0.00020479267,0.00010668539,0.000080835074,0.00020785944,0.000030704232,0.00003856905,0.00044645608],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99712515,0.00028091186,0.000885614,0.0009771084,0.00035376937,0.00037747453],"domain_scores_gemma":[0.99736947,0.0005526011,0.0009154091,0.0009980755,0.000042817355,0.0001216519],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023236965,0.00054874126,0.0039570397,0.0010978932,0.00029263378,0.00010497677,0.0007333003,0.0002231368,0.00016917718],"category_scores_gemma":[0.0003848154,0.00038546722,0.0013997405,0.0018866918,0.00030678752,0.00019523797,0.00026247726,0.00038736392,0.000003095434],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028510636,0.0024441513,0.0008045269,0.02647684,0.1604583,0.00015266707,0.0025381327,0.000024013683,0.00016819751,0.0020422793,0.011112388,0.7934934],"study_design_scores_gemma":[0.0007543817,0.000109378074,0.00030216385,0.0007484868,0.13617527,0.00003540091,0.00006102058,0.00004342687,0.000018832665,0.00018663157,0.8608205,0.0007445381],"about_ca_topic_score_codex":0.000050786046,"about_ca_topic_score_gemma":0.00016115559,"teacher_disagreement_score":0.8497081,"about_ca_system_score_codex":0.00005297478,"about_ca_system_score_gemma":0.00012154864,"threshold_uncertainty_score":0.99985975},"labels":[],"label_agreement":null},{"id":"W2586728661","doi":"10.1093/schbul/sbw221","title":"Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis","year":2017,"lang":"en","type":"review","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":244,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Kynurenic acid; Schizophrenia (object-oriented programming); Meta-analysis; Psychology; Neuroscience; Medicine; Psychiatry; Internal medicine; NMDA receptor","score_opus":0.11774986575986487,"score_gpt":0.3487109769739199,"score_spread":0.23096111121405502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586728661","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[9.179397e-7,0.99279153,0.0000063201624,0.0011059247,0.000104714905,0.004781231,0.0002805959,0.00015541485,0.0007733693],"genre_scores_gemma":[0.00006067421,0.9936714,0.00030445124,0.0010812792,0.00005341092,0.0019901304,0.000045455265,0.00014496855,0.002648195],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99112743,0.0023946674,0.0024859137,0.0022826528,0.0008009744,0.00090834365],"domain_scores_gemma":[0.9933825,0.0008703279,0.0022062757,0.0031433483,0.000056878467,0.00034063376],"candidate_categories":["metaepi_narrow","metaepi_broad","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.0015682819,0.0015626788,0.016985957,0.0013363194,0.00039280494,0.00049980485,0.0024289784,0.00060861476,0.002105982],"category_scores_gemma":[0.0040073963,0.00108498,0.005459397,0.0017790358,0.0004064442,0.00013991592,0.00062636944,0.0014487846,0.0018337657],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034083485,0.00011361312,4.671772e-8,0.96191144,0.026210047,0.00016944844,0.000020444211,2.4257056e-7,0.0000013913113,0.00083726144,0.0016110452,0.009090938],"study_design_scores_gemma":[0.00062816835,0.00003653461,5.814522e-7,0.04324886,0.6814411,0.00015032825,0.0000037084699,0.0000011780678,0.000004777422,0.00014654668,0.27314255,0.0011956356],"about_ca_topic_score_codex":0.0000316889,"about_ca_topic_score_gemma":0.00011293204,"teacher_disagreement_score":0.9186626,"about_ca_system_score_codex":0.000094222414,"about_ca_system_score_gemma":0.00027606942,"threshold_uncertainty_score":0.99971217},"labels":[],"label_agreement":null},{"id":"W2586887960","doi":"10.71781/27626","title":"Dérèglement des cytokines inflammatoires chez les schizophrènes avec abus de substances","year":2006,"lang":"fr","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; AstraZeneca; Eli Lilly and Company","keywords":"Medicine; Psychology","score_opus":0.007665124327326996,"score_gpt":0.18546586997929165,"score_spread":0.17780074565196466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586887960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94467664,0.034962043,0.00023693881,0.000296835,0.0012601594,0.0005453991,0.00012842027,0.0002540643,0.017639475],"genre_scores_gemma":[0.9457531,0.0028229558,0.0010384945,0.0001213458,0.00036550156,0.00006029092,0.00027726288,0.00007250485,0.04948856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956606,0.0003686108,0.00072041305,0.0011465322,0.0010370426,0.0010667735],"domain_scores_gemma":[0.99786854,0.00029726225,0.0006754762,0.00048510762,0.00025614252,0.0004174637],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.00024547716,0.0008712105,0.00061132194,0.00050968403,0.012613255,0.00024433073,0.00094430795,0.0006401348,0.00015282242],"category_scores_gemma":[0.00017880046,0.0009913351,0.00052570907,0.00070993626,0.0016691699,0.00073135097,0.00018439004,0.0006114703,0.00007183853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027285665,0.0011303795,0.1973716,0.001384995,0.00040065846,0.008721565,0.09918978,0.012569675,0.5691387,0.07432193,0.0010311028,0.032011032],"study_design_scores_gemma":[0.0024482768,0.00019911902,0.43214017,0.0010333426,0.00030294375,0.0011251705,0.032607477,0.0020528338,0.48340702,0.0017144945,0.041385446,0.0015837104],"about_ca_topic_score_codex":0.06054647,"about_ca_topic_score_gemma":0.096446745,"teacher_disagreement_score":0.23476857,"about_ca_system_score_codex":0.0049339044,"about_ca_system_score_gemma":0.0020807162,"threshold_uncertainty_score":0.9992537},"labels":[],"label_agreement":null},{"id":"W2587897530","doi":"","title":"Astrocyte-Produced Factors Protect Retinal Ganglion Cells from Acute Metabolic Stress","year":2016,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Krembil Foundation","funders":"","keywords":"Astrocyte; Retinal; Ganglion; Retinal ganglion cell; Ophthalmology; Cell biology; Neuroscience; Chemistry; Medicine; Biology; Central nervous system","score_opus":0.044158137145276714,"score_gpt":0.31374812522509704,"score_spread":0.2695899880798203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2587897530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971916,0.00002686665,0.0000241732,0.00058560516,0.00073194597,0.0005807084,0.00020071524,0.00015013931,0.0005082112],"genre_scores_gemma":[0.99871033,0.0000073846318,0.0004720994,0.00028549597,0.00012966529,0.00006125407,0.000004207812,0.000030108522,0.000299475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99540323,0.00053671363,0.00040837715,0.0017561873,0.0008592283,0.001036268],"domain_scores_gemma":[0.9979377,0.0005535803,0.00033477994,0.00052952743,0.00013632119,0.00050813815],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.00044974906,0.000438144,0.0004369524,0.00032301125,0.0006320534,0.00012125586,0.0012756857,0.00015075771,0.00043247928],"category_scores_gemma":[0.0023577628,0.00028772568,0.00011627269,0.0015824905,0.007609169,0.0009399249,0.00042965513,0.00031705244,0.00030502927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005643129,0.000103690676,0.0065155067,0.0000030415295,0.0000100227235,0.00014034384,0.00068042707,0.0000023817063,0.99177426,0.00023071111,0.00003481379,0.00044837722],"study_design_scores_gemma":[0.0005033754,0.0004504322,0.043931365,0.000052378986,0.000013876111,0.000046849702,0.00017573069,0.000028615943,0.9504046,0.0039463,0.00007322256,0.0003732539],"about_ca_topic_score_codex":0.00012313668,"about_ca_topic_score_gemma":0.000002848445,"teacher_disagreement_score":0.04136965,"about_ca_system_score_codex":0.000098146564,"about_ca_system_score_gemma":0.00040009114,"threshold_uncertainty_score":0.9999575},"labels":[],"label_agreement":null},{"id":"W2588275242","doi":"10.1007/s40142-017-0112-y","title":"Recent Progress in Functional Genomic Studies of Depression and Suicide","year":2017,"lang":"en","type":"article","venue":"Current Genetic Medicine Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Epigenomics; Depression (economics); Genomics; Functional genomics; Biology; Psychiatry; Bioinformatics; Psychology; Genome; Neuroscience; Genetics; Gene; DNA methylation","score_opus":0.12515513061213035,"score_gpt":0.38048470914676635,"score_spread":0.255329578534636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2588275242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.927197,0.07029819,0.000018526971,0.00055741577,0.0013499436,0.0002397181,6.310721e-7,0.000011175484,0.00032743253],"genre_scores_gemma":[0.98433864,0.01539874,0.00004467112,0.000033267796,0.000110704845,0.000023444343,0.0000013108364,0.000007903265,0.000041304134],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986928,0.000044495453,0.00041646804,0.00039127193,0.00028842894,0.0001665162],"domain_scores_gemma":[0.99897045,0.00007696696,0.00041355923,0.0004150268,0.00005241342,0.00007157141],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023969318,0.000115404524,0.00024110026,0.0000914138,0.00012130446,0.000010603782,0.00010069598,0.000026975253,0.00003812222],"category_scores_gemma":[0.0011408436,0.000083423,0.000019429586,0.00005569337,0.00070689974,0.000047994843,0.00014442891,0.00009119318,0.0000011615738],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021873884,0.000065340035,0.57883936,0.000106935804,0.000004155763,0.00009959583,0.00023780008,0.0000045621855,0.019416684,0.000026214133,0.00090709154,0.4002704],"study_design_scores_gemma":[0.00060234056,0.000061430284,0.97597784,0.0004174697,0.000010966634,0.000151745,0.00006166254,0.000033474895,0.013123113,0.0011857353,0.008281374,0.000092828705],"about_ca_topic_score_codex":0.0000043359,"about_ca_topic_score_gemma":0.000010062518,"teacher_disagreement_score":0.40017757,"about_ca_system_score_codex":0.000019154413,"about_ca_system_score_gemma":0.000046527166,"threshold_uncertainty_score":0.34018913},"labels":[],"label_agreement":null},{"id":"W2588351378","doi":"10.1159/000454677","title":"Early Development of Parvalbumin-, Somatostatin-, and Cholecystokinin-Expressing Neurons in Rat Brain following Prenatal Immune Activation and Maternal Iron Deficiency","year":2016,"lang":"en","type":"article","venue":"Developmental Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Parvalbumin; Subiculum; Interneuron; Endocrinology; Offspring; Internal medicine; Somatostatin; Cholecystokinin; Hippocampus; Prefrontal cortex; Neuroscience; Biology; Dentate gyrus; Psychology; Pregnancy; Medicine; Inhibitory postsynaptic potential; Receptor","score_opus":0.017723401290820905,"score_gpt":0.24266598068093764,"score_spread":0.22494257939011675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2588351378","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99841505,0.000023152568,0.00062608597,0.00021016682,0.0002219011,0.00027871435,0.000005210588,0.000046584228,0.00017316113],"genre_scores_gemma":[0.9976294,0.0000151905915,0.0018819646,0.00032131543,0.000004319664,0.000020971238,6.33861e-7,0.000021178417,0.00010500995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99764127,0.00010859311,0.00051369664,0.00075934903,0.00048921845,0.000487888],"domain_scores_gemma":[0.9992694,0.00027432176,0.000191134,0.00013613254,0.0000114446,0.00011754906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026570895,0.00024674987,0.00021475747,0.00025790546,0.0003258586,0.00011868059,0.00032770925,0.00005042312,0.000005819215],"category_scores_gemma":[0.0006184935,0.00019843575,0.000028930168,0.0004511734,0.00041887307,0.0009517271,0.0003484153,0.000115623145,0.000004188981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032277087,0.000053919433,0.03454865,0.000031463773,3.19953e-7,0.0000193394,0.0015710874,0.0000015191602,0.9433033,0.0000891755,0.0000028791787,0.020346085],"study_design_scores_gemma":[0.00070592656,0.0000344022,0.42871985,0.00014447958,6.476812e-7,0.000032095268,0.00008142239,0.000023379986,0.5700083,0.00003623581,0.000052428106,0.0001608548],"about_ca_topic_score_codex":0.000015569818,"about_ca_topic_score_gemma":0.0000058033834,"teacher_disagreement_score":0.39417118,"about_ca_system_score_codex":0.00005928775,"about_ca_system_score_gemma":0.00015571064,"threshold_uncertainty_score":0.80919755},"labels":[],"label_agreement":null},{"id":"W2589361283","doi":"10.1016/j.psyneuen.2017.02.020","title":"Biomarker development: Current issues and perspectives","year":2017,"lang":"en","type":"letter","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Amygdala; Biomarker; Anxiety; Depression (economics); Mood; Psychology; Inflammation; Clinical psychology; Peripheral; Internal medicine; Medicine; Psychiatry; Neuroscience; Biology","score_opus":0.0914514605337021,"score_gpt":0.3391176875780616,"score_spread":0.2476662270443595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2589361283","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011569792,0.012645907,0.000022979762,0.95935667,0.005220484,0.0006059084,0.000048985254,0.00040828582,0.010121017],"genre_scores_gemma":[0.061052185,0.032427248,0.0005387045,0.85973334,0.0060329516,0.00044361618,0.000094756215,0.0005201817,0.039157033],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964645,0.00030881533,0.00033230204,0.0016190924,0.00031912574,0.000956199],"domain_scores_gemma":[0.99844426,0.00021560307,0.0002905237,0.00092324935,0.000040198836,0.00008618024],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000028641727,0.00056982366,0.00051470555,0.00040501665,0.00049379544,0.00019655815,0.0009800334,0.00021488433,0.00022024447],"category_scores_gemma":[0.00043637434,0.0005381368,0.000112183,0.00009850589,0.00097125786,0.00015095907,0.0003243444,0.0016966382,0.00055040733],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002826904,0.000076308635,0.000094936644,0.00011021229,0.000021964985,0.0013363867,0.00038916394,1.3883903e-8,0.0017892005,0.00031542787,0.9547375,0.041100617],"study_design_scores_gemma":[0.00057487085,0.000045631496,0.0034228154,0.00004094199,0.000010912611,0.0007099871,0.000025912057,0.0000019656475,0.0023609404,0.00078088127,0.9915198,0.00050531374],"about_ca_topic_score_codex":0.000009200926,"about_ca_topic_score_gemma":0.0000038095466,"teacher_disagreement_score":0.099623315,"about_ca_system_score_codex":0.000029736162,"about_ca_system_score_gemma":0.000067265784,"threshold_uncertainty_score":0.99970704},"labels":[],"label_agreement":null},{"id":"W2590249728","doi":"10.1038/tpj.2017.44","title":"New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation","year":2017,"lang":"en","type":"review","venue":"The Pharmacogenomics Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Alberta","funders":"Canada Research Chairs; National Institutes of Health; National Cancer Institute; European Federation of Pharmaceutical Industries and Associations; National Institute on Alcohol Abuse and Alcoholism; King's College London; National Institute of General Medical Sciences; National Institute for Health and Care Research; GlaxoSmithKline; European Commission; National Institute of Mental Health; Pfizer; Medical Research Council; National Human Genome Research Institute; Pharmaceutical Research and Manufacturers of America Foundation","keywords":"Pharmacogenomics; Imputation (statistics); Antidepressant; Star (game theory); Medicine; Pharmacology; Statistics; Psychiatry; Mathematics; Missing data","score_opus":0.11102177042999337,"score_gpt":0.38020310225076365,"score_spread":0.2691813318207703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2590249728","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15037295,0.8464458,0.00070935267,0.0008652852,0.00063979387,0.00075986946,0.00018215418,0.000016316226,0.000008477976],"genre_scores_gemma":[0.055230163,0.94327176,0.00020515715,0.0005723078,0.00058568263,0.000010787031,0.000009952019,0.00006055404,0.00005366157],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99451226,0.0028372875,0.0010780058,0.0006805768,0.00048268968,0.00040916295],"domain_scores_gemma":[0.992277,0.004383157,0.0021283838,0.0008436091,0.00013022897,0.00023757607],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0021501426,0.0006255529,0.0015620926,0.00027206272,0.002096581,0.00052065786,0.0018936715,0.00013896874,0.00003863844],"category_scores_gemma":[0.00066153926,0.00029933537,0.0006050818,0.0004819508,0.00077714317,0.00025044393,0.0008853329,0.001240057,0.0000073971632],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010056832,0.00006262986,0.000018910263,0.00036945258,0.0061062803,0.00024309922,0.014904229,0.0001504596,0.008880121,0.00010421845,0.0010046121,0.96715033],"study_design_scores_gemma":[0.0051784245,0.00020285581,0.0016117991,0.0014579042,0.03795658,0.0018032703,0.0024202478,0.0028937007,0.006303705,0.013546932,0.9247959,0.0018286494],"about_ca_topic_score_codex":0.0003733707,"about_ca_topic_score_gemma":0.00009744271,"teacher_disagreement_score":0.96532166,"about_ca_system_score_codex":0.00015399825,"about_ca_system_score_gemma":0.00059174286,"threshold_uncertainty_score":0.9999459},"labels":[],"label_agreement":null},{"id":"W2591817769","doi":"10.1007/s11010-017-2975-3","title":"Kynurenic acid downregulates IL-17/1L-23 axis in vitro","year":2017,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"International Collaboration On Repair Discoveries; University of British Columbia","funders":"Canadian Institutes of Health Research; WorkSafe Victoria; WorkSafeBC","keywords":"Kynurenic acid; Kynurenine; Chemistry; Cytokine; Kynurenine pathway; Inflammation; Flow cytometry; Cell biology; Biochemistry; Molecular biology; Immunology; Biology; Glutamate receptor; Receptor; Tryptophan; Amino acid","score_opus":0.008294613747651308,"score_gpt":0.2207469390202803,"score_spread":0.212452325272629,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2591817769","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99072397,0.0010702469,0.00012551092,0.0006181801,0.000067897374,0.00011584925,0.000024022953,0.00004478355,0.0072095417],"genre_scores_gemma":[0.99852836,0.000021733447,0.00010507499,0.0003821479,0.000036063586,0.000013888639,0.000023022472,0.000024552688,0.0008651748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985008,0.00003802907,0.00018330711,0.0006192084,0.00021417075,0.0004444686],"domain_scores_gemma":[0.99892,0.000020821544,0.0000979383,0.0007897591,0.000013553223,0.00015788857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000102284575,0.00023452142,0.0001976693,0.000045748926,0.00024627335,0.00019377367,0.000521571,0.00017601384,0.000046057605],"category_scores_gemma":[0.00026220956,0.00023456955,0.00011126457,0.00008423297,0.0003368519,0.00007912808,0.00021354495,0.00020580486,0.000023937117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043120413,0.00006147837,0.00007999083,0.000038662558,0.0000049916994,0.00019930473,0.000026918951,0.0000010316165,0.99737537,0.00010248841,0.00012908308,0.0019375661],"study_design_scores_gemma":[0.00071746175,0.000016544856,0.00016451498,0.000022767279,0.0000068260665,0.000022299295,0.0000449245,0.000059798793,0.99736917,0.0007547648,0.0005362667,0.00028464917],"about_ca_topic_score_codex":0.000014371018,"about_ca_topic_score_gemma":0.0000015854392,"teacher_disagreement_score":0.007804374,"about_ca_system_score_codex":0.000022097942,"about_ca_system_score_gemma":0.000034426554,"threshold_uncertainty_score":0.95654684},"labels":[],"label_agreement":null},{"id":"W2593014017","doi":"10.1016/j.bbi.2017.02.020","title":"Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression","year":2017,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":269,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Alberta","funders":"Lundbeckfonden; European Commission","keywords":"Depression (economics); Depressive symptoms; C-reactive protein; Association (psychology); Internal medicine; Medicine; Psychology; Clinical psychology; Psychiatry; Inflammation; Anxiety; Psychotherapist","score_opus":0.02080012346717941,"score_gpt":0.27237525092280895,"score_spread":0.25157512745562954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2593014017","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977318,0.00013192635,0.00003224576,0.00020074291,0.0000555354,0.0009833564,0.00005706161,0.00006339641,0.0007439013],"genre_scores_gemma":[0.9992876,0.000030221092,0.000060345596,0.00006311954,0.000038205337,0.00014345981,0.000013574255,0.000029374338,0.00033411317],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99801147,0.00038305353,0.00024864578,0.0006016571,0.00035054574,0.00040464045],"domain_scores_gemma":[0.9984105,0.00037549075,0.00038942258,0.0006335764,0.000046551264,0.00014442358],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031427253,0.00028364948,0.00032771655,0.0001215394,0.0010978349,0.00033886125,0.00039652278,0.0002362419,0.000024711315],"category_scores_gemma":[0.000610001,0.00023691425,0.00004195164,0.000111518435,0.0002845234,0.00086221116,0.00037787505,0.00058769225,0.000004662946],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011639908,0.0001526192,0.78085864,0.000013920991,0.000007497189,0.000018896855,0.00039827757,1.673207e-7,0.1974908,0.000013730754,0.000035243804,0.020893825],"study_design_scores_gemma":[0.002098569,0.00007266919,0.8074065,0.00014470672,0.000025642137,0.000011382525,0.000100608384,0.000007260637,0.18961687,0.00012000732,0.0001309135,0.00026490813],"about_ca_topic_score_codex":0.00065595907,"about_ca_topic_score_gemma":0.00017894377,"teacher_disagreement_score":0.026547832,"about_ca_system_score_codex":0.00009534729,"about_ca_system_score_gemma":0.000033796063,"threshold_uncertainty_score":0.96610826},"labels":[],"label_agreement":null},{"id":"W2594544642","doi":"10.1016/j.ymgme.2017.02.009","title":"Hypertryptophanemia due to tryptophan 2,3-dioxygenase deficiency","year":2017,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Alberta; Alberta Children's Hospital","funders":"Division of Chemistry; National Institute of General Medical Sciences; National Institute of Mental Health; National Institutes of Health","keywords":"Tryptophan; Dioxygenase; Loss of heterozygosity; Gene; Phenotype; Enzyme; Compound heterozygosity; Biology; Genetics; Biochemistry; Molecular biology; Chemistry; Amino acid","score_opus":0.018726171855750463,"score_gpt":0.2624674648882671,"score_spread":0.24374129303251665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2594544642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98608935,0.0029900721,0.0021337143,0.0007752479,0.00048388224,0.00034268148,0.000023131377,0.000056383473,0.007105527],"genre_scores_gemma":[0.9937477,0.00039491034,0.002157809,0.0031992712,0.000105735366,0.000029459883,0.000001378716,0.000044382585,0.00031935945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811983,0.00007147287,0.00022682492,0.0007086962,0.0003475986,0.0005255813],"domain_scores_gemma":[0.99842453,0.000028818786,0.000105765896,0.0010097994,0.00004181751,0.00038927206],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012096751,0.0002771897,0.0002982889,0.00012247851,0.0006392482,0.0003810774,0.000730153,0.00010683145,0.000047943708],"category_scores_gemma":[0.00051728426,0.00025864656,0.000102765945,0.00013050408,0.00019709175,0.000088504974,0.0003708402,0.00014030295,0.00009834487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014189509,0.000054664633,0.00001578626,0.000010348499,0.0000037705718,0.00016906732,0.00014832607,0.000022695594,0.95462996,0.01107722,0.00016217878,0.033691816],"study_design_scores_gemma":[0.0007956024,0.000046703593,0.018480914,0.000009274279,0.000014668786,0.00006763768,0.0000285019,0.00011467853,0.9353586,0.0038620196,0.04084014,0.0003812598],"about_ca_topic_score_codex":0.00002798806,"about_ca_topic_score_gemma":0.000006955699,"teacher_disagreement_score":0.04067796,"about_ca_system_score_codex":0.000008054975,"about_ca_system_score_gemma":0.000047973033,"threshold_uncertainty_score":0.9999866},"labels":[],"label_agreement":null},{"id":"W2595675373","doi":"10.3390/ijms18030651","title":"Neuroinflammation and Oxidative Stress in Psychosis and Psychosis Risk","year":2017,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":172,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health","keywords":"Psychosis; Neuroinflammation; Synaptic pruning; Schizophrenia (object-oriented programming); Neuroscience; Endophenotype; Prodrome; Disease; Oxidative stress; Psychology; Medicine; Psychiatry; Bioinformatics; Cognition; Inflammation; Biology; Pathology; Internal medicine","score_opus":0.06802178677102629,"score_gpt":0.38625434464243646,"score_spread":0.3182325578714102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2595675373","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04049609,0.95706016,0.00015609853,0.0003996988,0.00085645483,0.00021619679,0.000040740026,0.000006017112,0.00076856057],"genre_scores_gemma":[0.019756312,0.9798023,0.00027765174,0.000067942776,0.00006670944,0.0000052627115,7.474095e-7,0.000010028037,0.000013026336],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979375,0.0003009676,0.00054329354,0.0003710097,0.0006978755,0.00014934278],"domain_scores_gemma":[0.99804294,0.00029969972,0.0013723986,0.00012913499,0.0000779446,0.0000779007],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000563569,0.00020082342,0.00046590186,0.00066994963,0.00012580502,0.0004710629,0.0010872083,0.00008450765,0.000008564002],"category_scores_gemma":[0.0010295935,0.00015188813,0.00015230909,0.00018678623,0.00048628307,0.0004927094,0.00012378332,0.00033281674,0.0000029260577],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008833339,0.000052789317,0.00018715148,0.00012203543,0.000027930217,0.00010750323,0.0001280179,0.000008029776,0.00040864342,0.0004191113,0.000030616862,0.99849933],"study_design_scores_gemma":[0.0029291527,0.0010292464,0.0035801728,0.027193272,0.0003525556,0.0023587663,0.00036168032,0.0005032819,0.0067454474,0.012264984,0.94110304,0.00157839],"about_ca_topic_score_codex":0.000021264488,"about_ca_topic_score_gemma":0.00001907874,"teacher_disagreement_score":0.99692094,"about_ca_system_score_codex":0.00002799272,"about_ca_system_score_gemma":0.00008882908,"threshold_uncertainty_score":0.61938184},"labels":[],"label_agreement":null},{"id":"W2600090085","doi":"10.1093/schbul/sbx021.194","title":"136. Increased Expression of Early Complement Components in Frontal Cortex in Schizophrenia","year":2017,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Dorsolateral prefrontal cortex; Complement system; Prefrontal cortex; Biology; Schizophrenia (object-oriented programming); Synaptic pruning; Neuroscience; Psychology; Immunology; Inflammation; Antibody; Microglia; Cognition; Psychiatry","score_opus":0.034567130931797745,"score_gpt":0.2668990514734898,"score_spread":0.23233192054169205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2600090085","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962007,0.00005733489,0.000012319537,0.00056228833,0.0002785492,0.0005829657,0.00007752432,0.000052846597,0.0021754634],"genre_scores_gemma":[0.9983083,0.000024514185,0.0012551574,0.0001692172,0.00005509526,0.000045870176,0.000015836062,0.000038338505,0.00008767804],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9971012,0.0003051257,0.00070864544,0.0007449967,0.0005682131,0.00057185115],"domain_scores_gemma":[0.9982387,0.00016946415,0.00045633625,0.000944775,0.00002762676,0.00016311457],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034924454,0.00033386852,0.00052810455,0.0003332984,0.00028022824,0.00012347221,0.0012067708,0.00013647557,0.0008402238],"category_scores_gemma":[0.00051799574,0.0003280609,0.00012262752,0.0001598983,0.00037138295,0.00016747453,0.00048636275,0.00043899284,0.0002844228],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0050219507,0.000670817,0.029017264,0.000042507087,0.000003960162,0.00009578327,0.0002667268,0.000008796313,0.95955575,0.0011920537,0.0009207539,0.0032036204],"study_design_scores_gemma":[0.011636967,0.00014169278,0.79795194,0.00032036824,0.0000035739558,0.000005501371,0.00006285659,0.00012640613,0.1873278,0.0008091851,0.0012492313,0.00036447885],"about_ca_topic_score_codex":0.0024341387,"about_ca_topic_score_gemma":0.0006379399,"teacher_disagreement_score":0.77222794,"about_ca_system_score_codex":0.00006909744,"about_ca_system_score_gemma":0.00007421464,"threshold_uncertainty_score":0.99991715},"labels":[],"label_agreement":null},{"id":"W2600536493","doi":"10.2527/jas.2016.1179","title":"Comparison of plasma tryptophan-related metabolites in crossbred Piétrain and Duroc pigs1","year":2017,"lang":"en","type":"article","venue":"Journal of Animal Science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Institut National de la Recherche Agronomique","keywords":"Tryptophan; Internal medicine; Weaning; Crossbreed; Endocrinology; Metabolite; Metabolism; Biology; Chemistry; Animal science; Amino acid; Biochemistry; Medicine","score_opus":0.05336650999896706,"score_gpt":0.3600148705360127,"score_spread":0.30664836053704564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2600536493","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973666,0.00021728581,0.000007689089,0.00045310776,0.00025030045,0.00007814345,0.000004076226,0.0000060545044,0.0016167196],"genre_scores_gemma":[0.9993812,0.00006075453,0.00043526708,0.000053017422,0.00003084994,4.722009e-7,3.094686e-8,0.000006002158,0.000032414395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814105,0.00006141828,0.0006000398,0.00026159722,0.00060708023,0.00032883938],"domain_scores_gemma":[0.9984552,0.00017824535,0.00087910856,0.00021080731,0.00011308118,0.00016351923],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008686173,0.00012402984,0.00037821973,0.00028628242,0.00039286993,0.00026319848,0.0010344675,0.000053115753,0.000033938406],"category_scores_gemma":[0.003624871,0.0000977145,0.00007333206,0.00041905945,0.0018718397,0.001128712,0.00016127768,0.00026810492,0.000003630837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018646588,0.00013722686,0.0148069225,0.000009454189,0.0000019131653,0.000024136485,0.00092507806,0.000013007939,0.9791191,0.0023926105,0.00002954252,0.0023545448],"study_design_scores_gemma":[0.0009785097,0.0003595209,0.3863837,0.000041164203,0.000003848321,0.00005377831,0.00031220843,0.0010185986,0.60986954,0.00079470983,0.00009818664,0.000086228],"about_ca_topic_score_codex":0.000016455107,"about_ca_topic_score_gemma":0.0000138813975,"teacher_disagreement_score":0.37157682,"about_ca_system_score_codex":0.000025704176,"about_ca_system_score_gemma":0.00022401518,"threshold_uncertainty_score":0.68968713},"labels":[],"label_agreement":null},{"id":"W2600853092","doi":"10.1093/schbul/sbx021.278","title":"200. Neuroinflammation in Individuals at Clinical High Risk for Psychosis: A PET Study With [(18)F]-FEPPA","year":2017,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Translocator protein; Neuroinflammation; Positron emission tomography; Psychosis; Prefrontal cortex; Psychology; Dorsolateral prefrontal cortex; Binding potential; Medicine; Internal medicine; Neuroscience; Psychiatry; Cognition; Inflammation","score_opus":0.03905492986781338,"score_gpt":0.3198017109347264,"score_spread":0.28074678106691303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2600853092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992965,0.000017939792,0.00003350935,0.0037516283,0.0004604,0.0019134108,0.00009127678,0.000109966066,0.00065687357],"genre_scores_gemma":[0.9965692,0.000065126886,0.0016233458,0.00037398038,0.00022187778,0.00032784604,0.0000075249027,0.000056475164,0.0007546027],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99685943,0.0004989085,0.00064974005,0.0010293551,0.00045335662,0.000509205],"domain_scores_gemma":[0.9973654,0.00063116854,0.00066317146,0.0011405356,0.000044391953,0.00015531633],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010072311,0.00031850947,0.00043067444,0.00015514439,0.0008185799,0.0003024451,0.0009384974,0.00009518978,0.0004053195],"category_scores_gemma":[0.0025964521,0.0002667573,0.00012872863,0.00014030303,0.0002876728,0.00014855547,0.00023568705,0.00043017688,0.0004983228],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012802391,0.003481715,0.88966954,0.000073682924,0.00008790362,0.00021947928,0.0007541343,0.00013246201,0.002164738,0.0015144853,0.06567566,0.023423798],"study_design_scores_gemma":[0.017696025,0.0015655541,0.9589658,0.000060225673,0.000042531083,0.000019659972,0.00012528297,0.000091566355,0.0013685471,0.0010516355,0.018532285,0.0004809129],"about_ca_topic_score_codex":0.000150092,"about_ca_topic_score_gemma":0.0009021473,"teacher_disagreement_score":0.069296226,"about_ca_system_score_codex":0.000031668445,"about_ca_system_score_gemma":0.000052592834,"threshold_uncertainty_score":0.9999785},"labels":[],"label_agreement":null},{"id":"W2600904107","doi":"","title":"Examining the effects of hiit exercise on depressive symptoms and inflammation in university students","year":2016,"lang":"en","type":"article","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McMaster University","funders":"","keywords":"Mood; Physical therapy; Interval training; Medicine; Depression (economics); Aerobic exercise; Randomized controlled trial; Placebo; Profile of mood states; Beck Depression Inventory; Internal medicine; Psychology; Anxiety; Clinical psychology; Psychiatry","score_opus":0.011579140056529765,"score_gpt":0.2264897953683271,"score_spread":0.21491065531179734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2600904107","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982552,0.000007097267,0.000026619995,0.000057515426,0.000034552562,0.0001867417,5.456821e-7,0.000013881245,0.0014178796],"genre_scores_gemma":[0.999454,0.00006949411,0.0000027035423,0.00003752514,0.0000033214442,0.0000013437877,4.2868326e-8,0.0000025328754,0.00042903706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99955934,0.000056414963,0.000051804545,0.0001329916,0.00012442179,0.00007499756],"domain_scores_gemma":[0.9992257,0.00061636715,0.000037178477,0.00009811919,0.0000054034767,0.000017283819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047003392,0.000046693138,0.00005698285,0.000053592597,0.000034032328,0.000007794783,0.00014438629,0.000021290589,0.0000082987035],"category_scores_gemma":[0.00018331785,0.000025352294,0.000008511305,0.00009252213,0.000072543044,0.000103083046,0.00007066064,0.000027208293,0.000005661262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014160763,0.00007453521,0.10134533,0.000040353538,0.0000035821586,0.000021215395,0.0014505297,0.000006847837,0.78133434,0.0030781794,0.000048450132,0.112455055],"study_design_scores_gemma":[0.0012971605,0.000079866615,0.39131138,0.00016391804,0.0000027455153,2.7690348e-7,0.0001518065,0.000016823897,0.60670644,0.00018377215,0.000036436097,0.000049368737],"about_ca_topic_score_codex":0.0000079081565,"about_ca_topic_score_gemma":0.000010349168,"teacher_disagreement_score":0.28996605,"about_ca_system_score_codex":0.000012022138,"about_ca_system_score_gemma":0.0000049622768,"threshold_uncertainty_score":0.10338365},"labels":[],"label_agreement":null},{"id":"W2600971053","doi":"10.1093/schbul/sbx024.066","title":"SU68. Effect of Cannabis on Neuroinflammation in Clinical High Risk for Psychosis: An In Vivo PET Study With [18F]-FEPPA","year":2017,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Neuroinflammation; Translocator protein; Psychosis; Cannabis; Psychology; Schizophrenia (object-oriented programming); Dorsolateral prefrontal cortex; Medicine; Neuroprotection; Prefrontal cortex; Internal medicine; Psychiatry; Neuroscience; Cognition; Inflammation","score_opus":0.018637538082366092,"score_gpt":0.31089122188082613,"score_spread":0.29225368379846006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2600971053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960352,0.0000043988084,0.0000063977163,0.0014783957,0.00029994443,0.001870575,0.0000451538,0.00004446224,0.00021545835],"genre_scores_gemma":[0.99919826,0.00001662553,0.00021668982,0.00010295473,0.0000889481,0.00024143032,0.0000022916386,0.000040705043,0.00009207024],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99698496,0.0009115272,0.00060654467,0.0008057506,0.00033397574,0.00035722123],"domain_scores_gemma":[0.9978275,0.00056373264,0.00050252554,0.0009735145,0.000029646688,0.00010311011],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012904032,0.00027313226,0.00048747208,0.00021707155,0.00021350097,0.00010171769,0.0006879467,0.00006849338,0.00006621991],"category_scores_gemma":[0.0024269253,0.0002171472,0.000097313095,0.00015924672,0.00021349793,0.00011844533,0.00006394539,0.00040044563,0.000030283401],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.12139212,0.0073584467,0.78025377,0.00031791418,0.00005738419,0.00046656444,0.0011381692,0.0011552268,0.024000347,0.002049224,0.008100767,0.053710043],"study_design_scores_gemma":[0.02372988,0.012233695,0.93209827,0.00014583526,0.000027467615,0.000006353434,0.00009495139,0.00035141423,0.02942658,0.00031655267,0.00116303,0.00040599416],"about_ca_topic_score_codex":0.0010042194,"about_ca_topic_score_gemma":0.0048521175,"teacher_disagreement_score":0.15184446,"about_ca_system_score_codex":0.000023673705,"about_ca_system_score_gemma":0.000043049742,"threshold_uncertainty_score":0.88550055},"labels":[],"label_agreement":null},{"id":"W2601967957","doi":"10.1371/journal.pone.0173063","title":"Asthma, corticosteroid use and schizophrenia: A nationwide population-based study in Taiwan","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Chiayi Chang Gung Memorial Hospital; National Health Research Institutes; Chang Gung Medical Foundation","keywords":"Medicine; Asthma; Schizophrenia (object-oriented programming); Incidence (geometry); Hazard ratio; Population; Comorbidity; Odds ratio; Retrospective cohort study; Pediatrics; Confounding; Diagnosis of schizophrenia; Cohort study; Psychiatry; Internal medicine; Confidence interval; Psychosis; Environmental health","score_opus":0.07439147188651742,"score_gpt":0.27268607706151327,"score_spread":0.19829460517499586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2601967957","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986982,0.000008290402,0.0000059396625,0.00064097275,0.000029134697,0.00047657322,0.000008697987,0.000043109656,0.00008911529],"genre_scores_gemma":[0.99928296,0.0000017529013,0.00025801302,0.0002960987,0.000018724972,0.000030699808,0.0000022625418,0.000013375925,0.000096138305],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990099,0.00007577251,0.0001667659,0.00030705472,0.0002840842,0.00015638693],"domain_scores_gemma":[0.99932593,0.0001089556,0.00010816681,0.00037570338,0.00002410458,0.000057138128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008074877,0.00009714485,0.0001457586,0.000112970134,0.00027028276,0.0003024001,0.00018939863,0.00003231307,0.000021893313],"category_scores_gemma":[0.002138934,0.00009721698,0.000015457985,0.00007895284,0.00004813406,0.00042383967,0.000061674364,0.00011113958,0.000017922139],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008723493,0.0017234713,0.9459645,0.000014018749,0.0000055429928,0.000017242022,0.00017384431,0.0000073497145,0.051344972,0.000106983665,0.0000032824914,0.00055156293],"study_design_scores_gemma":[0.0019050045,0.0001090108,0.9870425,0.000040162904,0.0000063183666,3.222972e-7,0.000039319722,0.001004913,0.009544713,0.00019498092,0.000002513399,0.00011024861],"about_ca_topic_score_codex":0.00015925725,"about_ca_topic_score_gemma":0.002060934,"teacher_disagreement_score":0.041800257,"about_ca_system_score_codex":0.000018788929,"about_ca_system_score_gemma":0.00002352481,"threshold_uncertainty_score":0.39643934},"labels":[],"label_agreement":null},{"id":"W2602908130","doi":"10.1186/s13195-017-0253-y","title":"Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain","year":2017,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":349,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Montreal Neurological Institute and Hospital; McGill University","funders":"Canadian Institutes of Health Research; Alzheimer's Association","keywords":"Selegiline; Monoamine oxidase B; Monoamine oxidase; Monoamine oxidase A; Neurology; Pharmacology; Medicine; Monoamine oxidase inhibitor; Geriatric psychiatry; Human brain; Clorgyline; Chemistry; Psychiatry; Parkinson's disease; Biochemistry; Internal medicine; Enzyme","score_opus":0.23033182064208652,"score_gpt":0.4330650590117566,"score_spread":0.2027332383696701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2602908130","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96943486,0.0023692609,0.0000018481812,0.018595405,0.0001706598,0.0010397916,0.000011026275,0.000065776345,0.008311394],"genre_scores_gemma":[0.9958889,0.0007264176,0.00003887596,0.001895963,0.00036318306,0.00018440238,0.0000050352282,0.00004884303,0.00084839814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99560267,0.0011025851,0.0003544518,0.0007713191,0.0011804521,0.0009884962],"domain_scores_gemma":[0.9970955,0.00094908965,0.00012114516,0.0015846831,0.00009431003,0.00015527036],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0025211629,0.00026871366,0.000249024,0.00030103515,0.0018065553,0.00078020466,0.0027648343,0.00010383837,0.00019919455],"category_scores_gemma":[0.0011379039,0.0001851121,0.0001249804,0.0005238703,0.0011361868,0.0005553365,0.00023737237,0.00092778355,0.00017555768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015969288,0.00059229526,0.00031053557,0.0000039746637,0.000040348037,0.00014345987,0.0032706766,0.0000018593116,0.8983609,0.0034970567,0.024669385,0.06894982],"study_design_scores_gemma":[0.0035282073,0.0006767371,0.037238833,0.000044977154,0.000005887943,0.000022890497,0.0016192781,0.00011260161,0.77527785,0.005978911,0.17500603,0.00048778873],"about_ca_topic_score_codex":0.00044430635,"about_ca_topic_score_gemma":0.00022355691,"teacher_disagreement_score":0.15033665,"about_ca_system_score_codex":0.000022986302,"about_ca_system_score_gemma":0.00012520979,"threshold_uncertainty_score":0.99949294},"labels":[],"label_agreement":null},{"id":"W2603070676","doi":"10.1080/13607863.2017.1293005","title":"Serum interleukin-6 is related to lower cognitive functioning in elderly patients with major depression","year":2017,"lang":"en","type":"article","venue":"Aging & Mental Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Depression (economics); Montgomery–Åsberg Depression Rating Scale; Major depressive disorder; Cognition; Internal medicine; Rating scale; Medicine; Psychology; Observational study; Effects of sleep deprivation on cognitive performance; Clinical psychology; Psychiatry; Developmental psychology","score_opus":0.014418625088819458,"score_gpt":0.2951732730234815,"score_spread":0.28075464793466204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2603070676","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99542516,0.000025880021,0.000030368896,0.0019835038,0.0004510681,0.00052721024,0.000028521792,0.000050803956,0.0014774974],"genre_scores_gemma":[0.9937451,0.0000068616046,0.00005049252,0.0055478294,0.00000976886,0.000014738627,0.000008625668,0.000021546763,0.0005950312],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998668,0.000068601796,0.00019570797,0.00044780032,0.00024206557,0.00037779738],"domain_scores_gemma":[0.99941456,0.000040751194,0.0001555817,0.00022701091,0.000018085067,0.00014402547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010982419,0.00013788375,0.00013939428,0.00010231256,0.000680054,0.0000995769,0.00019042459,0.000033860495,0.000096606396],"category_scores_gemma":[0.00006793352,0.00011807986,0.00002452854,0.00012648062,0.0000654838,0.00033453992,0.0001194933,0.00019692173,0.00008946214],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064879615,0.0005065447,0.7763681,0.000058160163,0.000009395292,0.000022825992,0.010905651,0.0000040244286,0.0010544253,0.000039695762,0.0014223483,0.20896006],"study_design_scores_gemma":[0.0043391227,0.0008918571,0.98203886,0.0011588999,0.0000026358641,0.0000051712514,0.0009554474,0.000067600566,0.009493926,0.00008827072,0.00070790853,0.00025028977],"about_ca_topic_score_codex":0.00033237872,"about_ca_topic_score_gemma":0.0003317259,"teacher_disagreement_score":0.20870976,"about_ca_system_score_codex":0.00012603925,"about_ca_system_score_gemma":0.00004771325,"threshold_uncertainty_score":0.5230494},"labels":[],"label_agreement":null},{"id":"W2603176710","doi":"10.1016/j.pnpbp.2017.03.024","title":"Targeting aggression in severe mental illness: The predictive role of genetic, epigenetic, and metabolomic markers","year":2017,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Seventh Framework Programme; European Commission","keywords":"Epigenetics; Schizophrenia (object-oriented programming); Aggression; Bipolar disorder; Mental illness; Autism spectrum disorder; Metabolomics; Phenotype; Autism; Psychology; Bioinformatics; Biology; Medicine; Genetics; Neuroscience; Psychiatry; Gene; Mental health; Cognition","score_opus":0.035762637784699784,"score_gpt":0.35056235492578763,"score_spread":0.31479971714108784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2603176710","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.114631034,0.88151014,6.072487e-7,0.00027899977,0.0015653243,0.001777274,0.00009640074,0.000029999828,0.000110195215],"genre_scores_gemma":[0.07080856,0.92815185,0.0001140953,0.000385037,0.00014157452,0.00035089548,0.000009482553,0.000031840216,0.0000066754014],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99546474,0.0015876391,0.00092645566,0.0012493327,0.0001769449,0.00059486745],"domain_scores_gemma":[0.99792475,0.00076389586,0.00084925967,0.00032616218,0.000015067674,0.00012086199],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048393215,0.00059328956,0.0013094132,0.0002517638,0.00032333084,0.0000453463,0.0009095957,0.00062384945,0.000061006554],"category_scores_gemma":[0.00024348816,0.00035215524,0.00020008037,0.00029526008,0.0019362232,0.00008052773,0.00048605533,0.0011350274,0.0000038417247],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008905639,0.00039745905,0.07165084,0.0009509626,0.0000432003,0.000031671327,0.00012074099,0.0000011854232,0.00009566832,0.000056080393,0.00022504623,0.9255366],"study_design_scores_gemma":[0.009587453,0.0017296197,0.29756728,0.007316657,0.0004469122,0.0004896618,0.0005688247,0.00035551042,0.000059413098,0.005032133,0.6746056,0.0022409293],"about_ca_topic_score_codex":0.00000293351,"about_ca_topic_score_gemma":0.000004069226,"teacher_disagreement_score":0.9232957,"about_ca_system_score_codex":0.000017699493,"about_ca_system_score_gemma":0.000092416565,"threshold_uncertainty_score":0.99989307},"labels":[],"label_agreement":null},{"id":"W2604335903","doi":"10.1097/wnr.0000000000000778","title":"Antidepressive-like effect of imperatorin from Angelica dahurica in prenatally stressed offspring rats through 5-hydroxytryptamine system","year":2017,"lang":"en","type":"article","venue":"Neuroreport","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Science North","funders":"Northwest University; National Natural Science Foundation of China","keywords":"Offspring; Hippocampus; Endocrinology; Internal medicine; Imperatorin; Behavioural despair test; Serotonin; Open field; Cortex (anatomy); Hippocampal formation; Psychology; Biology; Medicine; Neuroscience; Receptor; Antidepressant; Chemistry; Pregnancy","score_opus":0.01964534479762195,"score_gpt":0.2772741133985187,"score_spread":0.2576287686008968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604335903","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987897,0.000101976766,0.000013310077,0.000047134938,0.0009212592,0.00051221,0.000056089964,0.00013234704,0.010318699],"genre_scores_gemma":[0.9995229,0.000041476298,0.0000560691,0.00008921951,0.000113025904,0.000044610228,0.000007933767,0.0000477948,0.000076931574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997343,0.00022863426,0.0006279276,0.00080698956,0.00052406755,0.00046938192],"domain_scores_gemma":[0.9972236,0.00037785288,0.00071860687,0.0015353434,0.000030521085,0.0001140333],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019856713,0.00032191855,0.0005726054,0.00009413293,0.00022181933,0.00012566612,0.0008453064,0.00012247091,0.000018087061],"category_scores_gemma":[0.0015160443,0.00027806844,0.00013929697,0.00017795042,0.00020782562,0.00066328765,0.00036949044,0.00028781808,0.000016800732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012486495,0.00012659156,0.13931099,0.00017566548,0.00001121724,0.0012131773,0.00022968739,0.000030874995,0.8577343,0.00015476921,0.00019255417,0.00069530215],"study_design_scores_gemma":[0.0010208061,0.0001234564,0.2073915,0.00016709609,0.000011150103,0.000037698086,0.000017863089,0.0002068981,0.7902931,0.000017683833,0.00051160256,0.00020115775],"about_ca_topic_score_codex":0.0004871147,"about_ca_topic_score_gemma":0.000024754738,"teacher_disagreement_score":0.06808051,"about_ca_system_score_codex":0.000034732653,"about_ca_system_score_gemma":0.00006309997,"threshold_uncertainty_score":0.99996716},"labels":[],"label_agreement":null},{"id":"W2605549847","doi":"10.2174/1381612823666170111144340","title":"Role of Proinflammatory Cytokines in Dopaminergic System Disturbances, Implications for Anhedonic Features of MDD","year":2017,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Hospital; Sunnybrook Health Science Centre; University Health Network","funders":"","keywords":"Anhedonia; Proinflammatory cytokine; Kynurenine; Dopaminergic; Kynurenine pathway; Neuroscience; Tetrahydrobiopterin; Context (archaeology); Major depressive disorder; Dopamine; Psychology; Medicine; Inflammation; Biology; Internal medicine; Amygdala; Biochemistry; Tryptophan","score_opus":0.256811608312062,"score_gpt":0.44334070193183395,"score_spread":0.18652909361977194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605549847","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000022473216,0.994938,0.0004843632,0.000020066813,0.00040201645,0.0033274628,0.0003774484,0.00005510015,0.00037306038],"genre_scores_gemma":[0.010460521,0.98806906,0.000111046895,0.000005133487,0.00012909691,0.0010945023,0.0000326671,0.000053019474,0.00004494203],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972744,0.00039782125,0.0009756511,0.00067240436,0.00023847017,0.0004412376],"domain_scores_gemma":[0.9972241,0.0010534722,0.0008603319,0.0006533771,0.00007017864,0.00013852306],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039543942,0.00043938775,0.0014861727,0.0002676739,0.00010227177,0.000039679806,0.0011302913,0.00018259438,0.0000051381276],"category_scores_gemma":[0.0006057144,0.0003449203,0.0005035596,0.00032467296,0.00037980397,0.0001242166,0.000119937475,0.00040077334,0.00000743531],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048009326,0.00027758104,0.000009757007,0.041816488,0.00002065039,0.0000013520828,0.00002103978,0.000004297106,0.0022818863,0.015869442,0.0004969902,0.9391525],"study_design_scores_gemma":[0.0009272168,0.0000850255,0.0001786087,0.012054601,0.00031939588,0.000027007256,0.000010958188,0.00019524504,0.0059028827,0.0005430105,0.9792559,0.00050012465],"about_ca_topic_score_codex":0.0000011177106,"about_ca_topic_score_gemma":8.8343313e-7,"teacher_disagreement_score":0.97875893,"about_ca_system_score_codex":0.000103460494,"about_ca_system_score_gemma":0.0003924406,"threshold_uncertainty_score":0.9999003},"labels":[],"label_agreement":null},{"id":"W2606332452","doi":"10.1016/j.pnpbp.2017.04.023","title":"Depressive disorders: Processes leading to neurogeneration and potential novel treatments","year":2017,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Monoaminergic; Neurodegeneration; Neuroscience; Disease; Circadian rhythm; Oxidative stress; Medicine; Mood disorders; Cognition; Population; Cognitive decline; Mechanism (biology); Bioinformatics; Psychology; Psychiatry; Dementia; Biology; Internal medicine; Anxiety; Serotonin","score_opus":0.09917792114813914,"score_gpt":0.4089282058358412,"score_spread":0.30975028468770205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2606332452","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04038799,0.95361346,0.000019436135,0.0008800878,0.0024201977,0.0022930817,0.000098345095,0.000119226526,0.00016817644],"genre_scores_gemma":[0.03211061,0.9648476,0.00017741452,0.001618566,0.000352619,0.0007744953,0.000020878135,0.000051626434,0.00004619427],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962588,0.00041776508,0.00063798926,0.0018501893,0.00016471156,0.0006705597],"domain_scores_gemma":[0.9985389,0.00037975077,0.0004764613,0.00031987653,0.000023564236,0.0002614409],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013544579,0.00074286124,0.001210944,0.00034731868,0.0005263111,0.00020021471,0.0006794956,0.0005947818,0.000024535548],"category_scores_gemma":[0.00036062824,0.0005359584,0.00017338536,0.00038976438,0.000716724,0.00019037709,0.00034169885,0.0007239399,0.000021423846],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034287147,0.0010838042,0.012935783,0.0023663929,0.000060378134,0.00006760443,0.000038268,0.0000015936514,0.0001352468,0.000198964,0.00032440154,0.9824447],"study_design_scores_gemma":[0.010344927,0.0028140242,0.024412239,0.0035682626,0.0007515628,0.00084788847,0.000029336878,0.000042579955,0.000074401236,0.0019755133,0.9522539,0.0028853952],"about_ca_topic_score_codex":0.0000010655376,"about_ca_topic_score_gemma":0.000009685678,"teacher_disagreement_score":0.9795593,"about_ca_system_score_codex":0.000017850682,"about_ca_system_score_gemma":0.0001230927,"threshold_uncertainty_score":0.9997092},"labels":[],"label_agreement":null},{"id":"W2606663123","doi":"10.1016/j.cell.2017.03.040","title":"Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans","year":2017,"lang":"en","type":"article","venue":"Cell","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":255,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Great Ormond Street Hospital Charity; Royal Society; Medical Research Council Canada; Wellcome Trust","keywords":"Biology; Drug; Drug metabolism; Caenorhabditis elegans; Cancer; Metabolism; Host (biology); Cancer drugs; Mechanism (biology); Computational biology; Pharmacology; Genetics; Gene; Biochemistry","score_opus":0.019758734241967484,"score_gpt":0.2862127462880072,"score_spread":0.2664540120460397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2606663123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97426856,0.00042204058,0.000002375032,0.0008800754,0.0004444463,0.0001768304,0.000027481785,0.00005100914,0.023727199],"genre_scores_gemma":[0.9912756,0.00040169666,0.000018334495,0.0009915578,0.000084666906,0.000014237422,0.0000014477585,0.000021306018,0.0071911686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990049,0.000044662414,0.00013533678,0.00035068407,0.00012616951,0.0003382567],"domain_scores_gemma":[0.99927205,0.00009619406,0.000097182885,0.00044973454,0.0000101955075,0.00007466499],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006894719,0.00013605405,0.00015512019,0.000063596424,0.00024671768,0.0001536922,0.0006197777,0.00004495879,0.00023606433],"category_scores_gemma":[0.00015670758,0.00012326692,0.000055645243,0.00007623536,0.00020542354,0.00019676417,0.00008564714,0.00017386058,0.0003207685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018185734,0.00019199948,0.0017668105,0.00001784091,0.0000010602683,0.000026137173,0.0013097157,0.000009393963,0.98731416,0.00013738837,0.007606542,0.0016007836],"study_design_scores_gemma":[0.0011013376,0.000005649953,0.07908249,0.000015339432,0.000002533682,7.944878e-7,0.000066441025,0.000029587834,0.84520674,0.00007551905,0.07425173,0.00016181232],"about_ca_topic_score_codex":0.0003422686,"about_ca_topic_score_gemma":0.00019320638,"teacher_disagreement_score":0.14210738,"about_ca_system_score_codex":0.000017556622,"about_ca_system_score_gemma":0.000046554836,"threshold_uncertainty_score":0.5026679},"labels":[],"label_agreement":null},{"id":"W2607108802","doi":"10.1016/j.nlm.2017.04.005","title":"Maternal immune activation during pregnancy in rats impairs working memory capacity of the offspring","year":2017,"lang":"en","type":"article","venue":"Neurobiology of Learning and Memory","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Offspring; Neuroscience; Pregnancy; Immune system; Psychology; Working memory; Developmental psychology; Biology; Immunology; Cognition","score_opus":0.025294638137487196,"score_gpt":0.24677295897714058,"score_spread":0.22147832083965338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2607108802","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982109,0.000051593965,0.0000018780164,0.00012336322,0.00024610435,0.0001266465,5.9920075e-7,0.000019579302,0.0012193088],"genre_scores_gemma":[0.99956423,0.00007793345,0.00001399672,0.000015653215,0.000016860464,0.0000038615067,1.3785201e-7,0.000010054713,0.00029728087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901056,0.00024888988,0.00022618179,0.00024774403,0.00007211796,0.00019452296],"domain_scores_gemma":[0.99917835,0.00013703277,0.00040456068,0.00024828367,0.000011701017,0.000020066254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001304351,0.000104156636,0.00019620928,0.00007400248,0.00031872388,0.00001536511,0.0002965135,0.00007468312,0.000008747523],"category_scores_gemma":[0.00062716694,0.00008252559,0.00005504012,0.00005599032,0.00044181163,0.00010288025,0.00019037398,0.0003626566,7.6247545e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039552317,0.00001882856,0.095075734,0.000058099926,0.0000022443573,0.0000020503621,0.00044812018,0.0001523145,0.9015076,0.000021011741,3.233126e-7,0.0026741135],"study_design_scores_gemma":[0.000323086,0.000023662044,0.43252516,0.00024908734,0.0000015090056,0.000007686685,0.00007901305,0.000021947075,0.5667015,0.000019633886,0.000005316194,0.000042433887],"about_ca_topic_score_codex":0.00008555299,"about_ca_topic_score_gemma":0.0000137721745,"teacher_disagreement_score":0.33744943,"about_ca_system_score_codex":0.0000089967425,"about_ca_system_score_gemma":0.000016638814,"threshold_uncertainty_score":0.3365296},"labels":[],"label_agreement":null},{"id":"W2607899612","doi":"","title":"The Wnt5a-β-catenin Pathway Triggers a Metabolic Switch That Drives Indoleamine 2,3-dioxygenase Activity and Dendritic Cell Tolerization in the Melanoma Microenvironment.","year":2017,"lang":"en","type":"article","venue":"DukeSpace (Duke University)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Kite Pharma; Cancer Institute, University of Pittsburgh; Oregon Clinical and Translational Research Institute; Deutsches Zentrum für Lungenforschung; National Institutes of Health; M.J. Murdock Charitable Trust; Terry Fox Foundation; University of Pittsburgh; Midwest Athletes Against Childhood Cancer; National Institute of Allergy and Infectious Diseases; Dr. Miriam and Sheldon G. Adelson Medical Research Foundation; Harry J. Lloyd Charitable Trust; Achievement Rewards for College Scientists Foundation; Dana-Farber/Harvard Cancer Center; National Science Foundation","keywords":"Indoleamine 2,3-dioxygenase; Melanoma; WNT5A; Cancer research; Catenin; Metabolic pathway; Tumor microenvironment; Biology; Chemistry; Medicine; Wnt signaling pathway; Cell biology; Signal transduction; Tumor cells; Gene; Biochemistry","score_opus":0.015855606479051366,"score_gpt":0.20017808038751658,"score_spread":0.1843224739084652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2607899612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919837,0.0002884151,0.00012963811,0.0022849794,0.00009451631,0.00040700074,0.000015127914,0.000030525684,0.0047661136],"genre_scores_gemma":[0.9948599,0.0014201321,0.000020772875,0.00015693785,0.000021368915,0.000003056692,0.0000017815701,0.000016538877,0.0034995312],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840117,0.0003777118,0.00009119451,0.00046497083,0.00027124284,0.0003937055],"domain_scores_gemma":[0.99876255,0.00034888045,0.00019445896,0.0005942534,0.000010104789,0.00008977589],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0002046195,0.00022336173,0.00019649323,0.00017376462,0.001746751,0.00025681287,0.0009495564,0.00008865472,0.000011838076],"category_scores_gemma":[0.00015196021,0.00016355237,0.000080332225,0.00021750414,0.00055528904,0.00053463667,0.00040520687,0.00025764745,0.00001537254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019356409,0.0002074858,0.0029162737,0.000019617937,0.000011732581,0.00022697217,0.0029339625,0.000019476254,0.98431265,0.0038087633,0.0001026697,0.005246844],"study_design_scores_gemma":[0.002199977,0.00007642839,0.07538075,0.000019274665,0.000018328816,0.000015195993,0.004068265,0.00023264198,0.85719615,0.00007413913,0.06040977,0.00030906755],"about_ca_topic_score_codex":0.00010471417,"about_ca_topic_score_gemma":0.0005263913,"teacher_disagreement_score":0.12711647,"about_ca_system_score_codex":0.00005258647,"about_ca_system_score_gemma":0.00005179858,"threshold_uncertainty_score":0.99955285},"labels":[],"label_agreement":null},{"id":"W2608086188","doi":"10.1503/jpn.170060","title":"Smoking, psychiatric illness and the brain","year":2017,"lang":"en","type":"editorial","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Psychiatry; Medicine","score_opus":0.013551798447094582,"score_gpt":0.2830235917244276,"score_spread":0.269471793277333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2608086188","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015533335,0.0034294901,0.000052016425,0.011455698,0.9678239,0.00026423187,0.00003740182,0.00002120714,0.0013826746],"genre_scores_gemma":[0.14343539,0.017227914,0.00022477549,0.00784478,0.82821923,0.000013699895,0.0000010742602,0.00011339469,0.0029197377],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964739,0.00043590838,0.0006697884,0.0006770823,0.0013156976,0.00042762575],"domain_scores_gemma":[0.99565464,0.0016486396,0.0017963912,0.00056996517,0.00010098701,0.00022937874],"candidate_categories":["metaresearch","sts"],"consensus_categories":[],"category_scores_codex":[0.0014010475,0.00039142487,0.0006165716,0.00028528247,0.0015862039,0.0007962659,0.0017905193,0.00033924272,0.000011693111],"category_scores_gemma":[0.008356514,0.00023816325,0.00023270852,0.00031588098,0.002289238,0.00056680175,0.00026534987,0.0017392299,0.000001663022],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038030348,0.00012194388,0.0001762518,0.00012689819,0.0000061329074,0.000030516978,0.0001647989,0.0000025773966,0.0012853893,0.002751864,0.99328274,0.0016706021],"study_design_scores_gemma":[0.0049899677,0.000597038,0.0011478055,0.0002523126,0.00010098401,0.00048042653,0.000091505965,0.000069548354,0.0003744521,0.011154506,0.9801998,0.00054164306],"about_ca_topic_score_codex":0.0000068960617,"about_ca_topic_score_gemma":0.0000158264,"teacher_disagreement_score":0.13960472,"about_ca_system_score_codex":0.000012783623,"about_ca_system_score_gemma":0.0006312279,"threshold_uncertainty_score":0.99999654},"labels":[],"label_agreement":null},{"id":"W2608092979","doi":"10.1016/j.psyneuen.2017.04.015","title":"Tryptophan breakdown and cognition in bipolar disorder","year":2017,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Stroop effect; California Verbal Learning Test; Kynurenine; Psychology; Bipolar disorder; Kynurenine pathway; Cognition; Verbal memory; Audiology; Verbal learning; Mania; Neuroscience; Clinical psychology; Developmental psychology; Medicine","score_opus":0.02981522533235013,"score_gpt":0.2976570570029993,"score_spread":0.2678418316706492,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2608092979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857313,0.0005091299,0.00003988877,0.0048454897,0.0007154913,0.00026199338,0.000013793203,0.00009602504,0.007786909],"genre_scores_gemma":[0.9964603,0.0015487891,0.00003476867,0.001519948,0.000051946714,0.00003608545,0.0000016222792,0.000024249099,0.00032225164],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984064,0.00013755744,0.0002060763,0.0006275166,0.00011757702,0.0005048593],"domain_scores_gemma":[0.9991198,0.00011931865,0.000117024996,0.00054738886,0.00001105258,0.0000853673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000028802759,0.00018503175,0.00020316095,0.00019567803,0.0003620458,0.000105645835,0.0004287298,0.0000477648,0.00010787518],"category_scores_gemma":[0.00045385677,0.00018448694,0.000041232146,0.000086113694,0.00050325843,0.0002699184,0.00014842652,0.0002690396,0.00014411284],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048621447,0.0009584358,0.1074187,0.0000743118,0.000014825647,0.001067169,0.00040738174,0.000004948597,0.51746386,0.028679537,0.001611863,0.34181273],"study_design_scores_gemma":[0.0055728876,0.00028344517,0.82274747,0.00002477256,0.000009331549,0.00079703156,0.000088379646,0.00016608751,0.04371687,0.014474643,0.11160817,0.0005108971],"about_ca_topic_score_codex":0.0000791758,"about_ca_topic_score_gemma":0.00020408588,"teacher_disagreement_score":0.7153288,"about_ca_system_score_codex":0.0000069263046,"about_ca_system_score_gemma":0.000011011141,"threshold_uncertainty_score":0.75231594},"labels":[],"label_agreement":null},{"id":"W2608613170","doi":"10.1016/j.biopsych.2017.02.245","title":"231. Serotonin Transporter Gene Methylation and Antidepressant Treatment of Major Depressive Disorder","year":2017,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Antidepressant; Epigenetics; Serotonin transporter; DNA methylation; Major depressive disorder; Methylation; Antidepressant medication; Psychiatry; Medicine; Pharmacology; Bioinformatics; Psychology; Serotonin; Gene; Genetics; Internal medicine; Biology; Gene expression; Mood","score_opus":0.04520872218254511,"score_gpt":0.3004614968337388,"score_spread":0.25525277465119367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2608613170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961124,0.0011432217,0.00031551352,0.0008405775,0.00027812555,0.00037444182,0.00005656748,0.000037939666,0.0008411967],"genre_scores_gemma":[0.9983049,0.0006759123,0.0007124323,0.00014228896,0.00006317131,0.000032060336,0.0000063612374,0.000008834661,0.000054026084],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989877,0.00007100281,0.00021103762,0.00043663502,0.000095434945,0.0001982216],"domain_scores_gemma":[0.99929553,0.000062431485,0.00018869502,0.00037222155,0.000011664726,0.00006947731],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004354154,0.00016546309,0.0002336809,0.00003305625,0.0002747556,0.000034780613,0.00021904235,0.00012734962,0.000080608545],"category_scores_gemma":[0.00006289896,0.000104432365,0.00009909657,0.0000361778,0.0003316568,0.00009727232,0.00003043353,0.000053048516,0.0000071224104],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022794526,0.00061876565,0.7063132,0.000016912623,0.000021267237,0.000007130451,0.000100491656,0.0000048492725,0.27812642,0.002174296,0.00003932852,0.012349433],"study_design_scores_gemma":[0.0017852691,0.0004368553,0.88853985,0.00001042444,0.000013880385,0.0000056073222,0.000029535082,0.000039962626,0.10447008,0.003897868,0.0006105448,0.00016014522],"about_ca_topic_score_codex":0.00005559877,"about_ca_topic_score_gemma":0.000030142215,"teacher_disagreement_score":0.18222666,"about_ca_system_score_codex":0.000005628541,"about_ca_system_score_gemma":0.000015345964,"threshold_uncertainty_score":0.42586282},"labels":[],"label_agreement":null},{"id":"W2609313774","doi":"10.3892/ijo.2017.3975","title":"Gene silencing of indoleamine 2,3-dioxygenase hinders tumor growth through angiogenesis inhibition","year":2017,"lang":"en","type":"article","venue":"International Journal of Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Gene silencing; Angiogenesis; Gene knockdown; Cancer research; Biology; Small hairpin RNA; Small interfering RNA; Oncogene; Indoleamine 2,3-dioxygenase; RNA interference; Neovascularization; Cancer; Cell cycle; Transfection; Apoptosis; RNA; Gene; Genetics","score_opus":0.046300042688425164,"score_gpt":0.3319601476051523,"score_spread":0.2856601049167271,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2609313774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928479,0.00006868245,0.0008763121,0.002141903,0.0013111215,0.000060348924,0.000020824957,0.000007880993,0.0026650268],"genre_scores_gemma":[0.9973007,0.00014511045,0.0010137429,0.0010971364,0.00039137027,0.0000017725012,0.0000013351083,0.000012036825,0.000036793943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99862397,0.0000970667,0.0005021283,0.00016021407,0.00046148393,0.00015511645],"domain_scores_gemma":[0.9979579,0.0002150298,0.0012490929,0.00014783083,0.00036920048,0.00006094887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024824447,0.00010858879,0.00024806234,0.00020034461,0.00010825008,0.00004523089,0.0006950936,0.00006746438,0.0000988158],"category_scores_gemma":[0.0014769895,0.00009654094,0.00018164204,0.000056205434,0.00024760675,0.0005405101,0.00012384815,0.00015607828,0.0000110222845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030522209,0.00028900194,0.00065193174,0.000007732956,0.000050101742,0.0006947819,0.00047198412,0.000061025385,0.98968947,0.0012639939,0.0007351488,0.005779603],"study_design_scores_gemma":[0.0019010446,0.0004043164,0.010771608,0.000045276007,0.0000071434624,0.00082959916,0.0001749753,0.000036124497,0.9818791,0.0031291505,0.0007319605,0.000089683854],"about_ca_topic_score_codex":0.000057606107,"about_ca_topic_score_gemma":0.000017417151,"teacher_disagreement_score":0.010119677,"about_ca_system_score_codex":0.0001497271,"about_ca_system_score_gemma":0.00021049779,"threshold_uncertainty_score":0.39368254},"labels":[],"label_agreement":null},{"id":"W2613803567","doi":"","title":"Peripheral sub-inflammation is associated with antidepressant ă consumption in schizophrenia. Results from the multi-center FACE-SZ data ă set","year":2016,"lang":"en","type":"preprint","venue":"RePEc: Research Papers in Economics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Internal medicine; Medicine; Confounding; Depression (economics); Antidepressant; Odds ratio; Schizophrenia (object-oriented programming); Comorbidity; Major depressive disorder; Bipolar disorder; Psychiatry; Psychology","score_opus":0.09833947537286741,"score_gpt":0.331648631864761,"score_spread":0.2333091564918936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2613803567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98853165,0.000056168923,0.000014929827,0.001671902,0.0002696576,0.0013155434,0.006815291,0.00006602099,0.0012588219],"genre_scores_gemma":[0.9924994,0.005484364,0.000105088075,0.00020262609,0.00012991445,0.000103508566,0.0011288263,0.00006811166,0.0002781497],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99474365,0.0011524403,0.00084084016,0.0019337885,0.0004952228,0.00083406345],"domain_scores_gemma":[0.9949717,0.0020570294,0.00043586266,0.0023479848,0.000060975148,0.00012646195],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018129377,0.00040972373,0.0004898249,0.0002688853,0.00022397152,0.00037438294,0.0020904264,0.00044080423,0.000059685237],"category_scores_gemma":[0.0035883908,0.0002989446,0.00008422224,0.00016919851,0.00067338196,0.00042082244,0.0020853365,0.0017021796,0.000035993584],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022864163,0.003550686,0.35996717,0.000471753,0.0006674522,0.0008488327,0.020166589,0.014344683,0.08386863,0.00036106555,0.0048540863,0.48803487],"study_design_scores_gemma":[0.06032104,0.00026518904,0.6562127,0.005142036,0.000037906113,0.000026811425,0.0020189919,0.22322206,0.03674327,0.00190051,0.010863636,0.0032458955],"about_ca_topic_score_codex":0.00023965417,"about_ca_topic_score_gemma":0.0050891577,"teacher_disagreement_score":0.48478898,"about_ca_system_score_codex":0.0006289378,"about_ca_system_score_gemma":0.0003869236,"threshold_uncertainty_score":0.9999463},"labels":[],"label_agreement":null},{"id":"W2614896896","doi":"10.1016/j.bbr.2017.04.057","title":"Two-hit model of schizophrenia induced by neonatal immune activation and peripubertal stress in rats: Study of sex differences and brain oxidative alterations","year":2017,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":77,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Oxidative stress; Schizophrenia (object-oriented programming); Immune system; Psychology; Neuroscience; Endocrinology; Internal medicine; Developmental psychology; Medicine; Psychiatry; Immunology","score_opus":0.1332093411532705,"score_gpt":0.3839287177229232,"score_spread":0.2507193765696527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2614896896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978632,0.00002633779,0.000011732556,0.0010961249,0.000017299757,0.00078335375,0.00011032601,0.00000944484,0.000082221784],"genre_scores_gemma":[0.9995939,0.000008998977,0.000040264807,0.000017236896,0.000007776906,0.00006158993,0.000009428882,0.000013833112,0.0002469621],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997794,0.00050918513,0.00032922637,0.00046662157,0.00058864366,0.00031237712],"domain_scores_gemma":[0.9985217,0.00075674575,0.0001652432,0.00037971747,0.00009077581,0.00008585464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005081345,0.00015852586,0.00027475433,0.00026970956,0.0004837558,0.00019412689,0.00045048076,0.00007408448,0.00001792973],"category_scores_gemma":[0.0014376291,0.00014121595,0.00002533027,0.0002031794,0.0006035135,0.0006016216,0.00037429066,0.00041685166,3.8159666e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019105438,0.00047469756,0.042348538,0.000016243457,0.000005317589,0.0000028943537,0.006631135,0.000007513784,0.9428912,0.00032186127,0.000020518959,0.0070890705],"study_design_scores_gemma":[0.003125767,0.00060737535,0.47732577,0.00006118099,0.0000029193945,0.0000014637624,0.008755831,0.003999692,0.5056399,0.0003112574,3.8033383e-7,0.00016846647],"about_ca_topic_score_codex":0.0030475773,"about_ca_topic_score_gemma":0.0014730345,"teacher_disagreement_score":0.43725127,"about_ca_system_score_codex":0.000024546152,"about_ca_system_score_gemma":0.00008413472,"threshold_uncertainty_score":0.57586193},"labels":[],"label_agreement":null},{"id":"W2617510176","doi":"10.1007/s00406-017-0812-z","title":"A longitudinal study of neurotrophic, oxidative, and inflammatory markers in first-onset depression in midlife women","year":2017,"lang":"en","type":"article","venue":"European Archives of Psychiatry and Clinical Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Queen's University; St. Joseph’s Healthcare Hamilton","funders":"National Institute of Mental Health","keywords":"Depression (economics); Longitudinal study; Oxidative stress; Psychology; Medicine; Internal medicine; Clinical psychology; Psychiatry; Oncology; Endocrinology; Pathology","score_opus":0.0447183548754392,"score_gpt":0.32727454977851456,"score_spread":0.2825561949030754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2617510176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972726,0.00003437023,0.000011077329,0.00021016687,0.0003407283,0.0003716199,0.000008799917,0.0000135268265,0.0017370709],"genre_scores_gemma":[0.9991337,0.00043939654,0.00012468429,0.00022919687,0.000023052362,0.000005594647,1.2853079e-7,0.000015904452,0.000028337992],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99670756,0.001020486,0.00079632126,0.0008865259,0.00025490942,0.00033421448],"domain_scores_gemma":[0.99796116,0.00073729485,0.00049051613,0.0006202499,0.000006835629,0.00018391776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072552677,0.00019473712,0.00035466932,0.00021190952,0.000263401,0.000065049906,0.00088998873,0.00002754842,0.0000041413027],"category_scores_gemma":[0.002188569,0.00017202142,0.000056359,0.00017209373,0.0019693447,0.00030010915,0.0007142262,0.00040272088,0.0000011661422],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00062074244,0.0011702575,0.99135375,0.00006964308,0.0000013819439,0.000060145914,0.00061442424,0.000017378232,0.0038610096,0.00009432539,0.0000056670615,0.0021312688],"study_design_scores_gemma":[0.0025452909,0.0011236421,0.99461675,0.00017395966,0.0000029812368,0.000009319135,0.0003220842,0.000411147,0.00011438268,0.00050143944,0.000026262354,0.00015274425],"about_ca_topic_score_codex":0.000018969033,"about_ca_topic_score_gemma":0.00016198219,"teacher_disagreement_score":0.0037466271,"about_ca_system_score_codex":0.0000026231487,"about_ca_system_score_gemma":0.000043226435,"threshold_uncertainty_score":0.7256133},"labels":[],"label_agreement":null},{"id":"W2619113745","doi":"10.1016/j.cpet.2017.02.008","title":"Novel Phenotypes Detectable with PET in Mood Disorders","year":2017,"lang":"en","type":"review","venue":"PET Clinics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Radioligand; Medicine; Phenotype; Translocator protein; Monoamine oxidase; Major depressive disorder; Affect (linguistics); Anterior cingulate cortex; Prefrontal cortex; Neuroscience; Monoamine oxidase A; Cingulate cortex; Mood; Psychiatry; Clinical psychology; Internal medicine; Receptor; Psychology; Genetics; Serotonin; Biology; Cognition; Gene; Central nervous system; Biochemistry","score_opus":0.1048363299677687,"score_gpt":0.375584992675085,"score_spread":0.2707486627073163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2619113745","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014063783,0.9749795,0.00012312742,0.00009601868,0.0007614389,0.0012656294,0.00019882928,0.00016361759,0.022271162],"genre_scores_gemma":[0.0006121411,0.9966924,0.00051926,0.00012348188,0.00009922508,0.00010702143,0.000019185925,0.00011712683,0.0017101491],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99719554,0.00014911706,0.0006957036,0.001000401,0.00035182323,0.0006074299],"domain_scores_gemma":[0.99706024,0.0009938759,0.000690307,0.0011162133,0.000020403882,0.00011898915],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034436202,0.00055095745,0.0015108661,0.00021796512,0.00020629638,0.00017520152,0.0013074314,0.0001605408,0.000085074505],"category_scores_gemma":[0.0017893331,0.00042126814,0.00034932018,0.00037084648,0.0002967308,0.00019675665,0.00021880073,0.0008629266,0.00027926444],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030727864,0.0003984474,0.000033195294,0.0037766169,0.000023775314,0.00005225173,0.000053440144,0.000009181631,0.000003131596,0.0004473649,0.0001086778,0.9950632],"study_design_scores_gemma":[0.0009197858,0.00013192718,0.00003072799,0.0028734358,0.00009052928,0.000095603005,0.000018813409,0.000069189016,0.0000030199049,0.00039080397,0.9947386,0.0006375659],"about_ca_topic_score_codex":0.00004949249,"about_ca_topic_score_gemma":0.002112611,"teacher_disagreement_score":0.9946299,"about_ca_system_score_codex":0.00005176941,"about_ca_system_score_gemma":0.00048044938,"threshold_uncertainty_score":0.9998239},"labels":[],"label_agreement":null},{"id":"W2620846733","doi":"","title":"Moclobemide response in depressed patients: Association study with a functional polymorphism in the monoamine oxidase-A promoter","year":2000,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Moclobemide; Monoamine oxidase A; Monoamine oxidase; Polymorphism (computer science); Medicine; Monoamine neurotransmitter; Monoamine oxidase B; Association (psychology); Internal medicine; Psychology; Pharmacology; Psychiatry; Endocrinology; Genotype; Genetics; Serotonin; Biology; Receptor; Gene; Psychotherapist; Biochemistry; Enzyme; Antidepressant","score_opus":0.011661487743940107,"score_gpt":0.24347043379388586,"score_spread":0.23180894604994576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2620846733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995124,0.00019609221,0.0000650841,0.0037560803,0.0002782829,0.0004805224,0.0000063577468,0.000010479613,0.00008309344],"genre_scores_gemma":[0.9957577,0.00057743664,0.00019197057,0.0031867598,0.000177452,0.000017445027,0.0000011698578,0.000035628247,0.00005446029],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99324036,0.002238596,0.0009815965,0.00041115494,0.0026352936,0.0004930167],"domain_scores_gemma":[0.99778014,0.00093086524,0.00058595696,0.0003636626,0.000097424796,0.00024196925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014730731,0.00026535775,0.00038761957,0.00035312987,0.000084593274,0.000065609594,0.0008488193,0.000084566906,0.00018019589],"category_scores_gemma":[0.0009961067,0.0001834817,0.00009304312,0.0017730383,0.00021608372,0.0000587571,0.000048408478,0.0008090703,0.000015535647],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007516836,0.009093766,0.8871388,0.000011978488,0.000049556013,0.0006830509,0.0029835051,0.0067428467,0.001637451,0.000004960694,0.0019309323,0.08220633],"study_design_scores_gemma":[0.0054338924,0.0076609487,0.982467,0.000028353383,0.00003894677,0.00009855407,0.00052693626,0.0006415155,0.00019005623,0.000039476643,0.002634427,0.00023992006],"about_ca_topic_score_codex":0.000018532333,"about_ca_topic_score_gemma":0.000043952434,"teacher_disagreement_score":0.09532819,"about_ca_system_score_codex":0.00007640322,"about_ca_system_score_gemma":0.00032856312,"threshold_uncertainty_score":0.7482166},"labels":[],"label_agreement":null},{"id":"W2623849798","doi":"10.1111/bdi.12496","title":"A pilot, open‐label, 8‐week study evaluating the efficacy, safety and tolerability of adjunctive minocycline for the treatment of bipolar I/II depression","year":2017,"lang":"en","type":"article","venue":"Bipolar Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital; University of Toronto; University Health Network","funders":"Beijing Cultural Development Foundation","keywords":"Tolerability; Adjunctive treatment; Minocycline; Hamd; Bipolar disorder; Young Mania Rating Scale; Internal medicine; Medicine; Major depressive disorder; Hamilton Rating Scale for Depression; Depression (economics); Rating scale; Montgomery–Åsberg Depression Rating Scale; Clinical Global Impression; Psychiatry; Psychology; Adverse effect; Cognition; Mania; Lithium (medication)","score_opus":0.12975466754096476,"score_gpt":0.38329563106595016,"score_spread":0.2535409635249854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2623849798","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850658,0.008635295,0.00019597198,0.00076142454,0.00021331779,0.004878122,0.00013884579,0.000019003555,0.00009218703],"genre_scores_gemma":[0.99674445,0.0026856693,0.0001518365,0.000060524286,0.000026550653,0.0001779266,0.0000035336668,0.000025512145,0.00012397961],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99785805,0.00041395484,0.00048409626,0.00059601356,0.0003512584,0.00029664492],"domain_scores_gemma":[0.995627,0.0024222187,0.00055999163,0.0012593644,0.00007147269,0.000059957732],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0008669527,0.00026188523,0.00043099438,0.000045930647,0.0020057699,0.0000973603,0.0011529075,0.00004354699,0.000019888817],"category_scores_gemma":[0.0025068377,0.00014126983,0.00010846784,0.00013526969,0.000766368,0.00021883758,0.00045458323,0.00010711644,9.149677e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004662945,0.012288173,0.05974197,0.000048341913,0.00014071281,3.9861052e-7,0.0063361516,0.00009169501,0.067522995,0.0002166353,0.00004573032,0.84890425],"study_design_scores_gemma":[0.025776615,0.028464442,0.88843936,0.00007117279,0.00033077956,0.000001827015,0.002719333,0.0059430855,0.024358358,0.0008990453,0.022551417,0.00044454538],"about_ca_topic_score_codex":0.0015511254,"about_ca_topic_score_gemma":0.0018878903,"teacher_disagreement_score":0.8484597,"about_ca_system_score_codex":0.00003114186,"about_ca_system_score_gemma":0.00008424384,"threshold_uncertainty_score":0.9992935},"labels":[],"label_agreement":null},{"id":"W2624751168","doi":"10.1007/s12035-017-0632-1","title":"Peripheral Alterations in Cytokine and Chemokine Levels After Antidepressant Drug Treatment for Major Depressive Disorder: Systematic Review and Meta-Analysis","year":2017,"lang":"en","type":"review","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":454,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; National Institute for Health and Care Research","keywords":"Antidepressant; Medicine; Major depressive disorder; Meta-analysis; Internal medicine; Inflammation; Peripheral; Cytokine; Pharmacology; Immunology; Amygdala","score_opus":0.08237821713831807,"score_gpt":0.35286150827033774,"score_spread":0.2704832911320197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2624751168","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023788269,0.9924731,0.00022055354,0.00042390646,0.00003799142,0.0055250158,0.001029106,0.000026073369,0.000026325366],"genre_scores_gemma":[0.0047743996,0.9883772,0.00006894972,0.0012282629,0.000010003737,0.0048008165,0.000106266045,0.00006548859,0.0005685724],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99608225,0.0011116683,0.00094965304,0.0013309931,0.00009837604,0.0004270593],"domain_scores_gemma":[0.99768704,0.00047119235,0.00067815906,0.0010305298,0.000034265664,0.00009880392],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001903465,0.00074372714,0.006187974,0.0003175856,0.00017706655,0.00012799387,0.0004068694,0.00018393707,0.000054749573],"category_scores_gemma":[0.00054864434,0.0004837374,0.0015090461,0.00027273866,0.00023712961,0.000087515546,0.00019978957,0.00019611926,0.0000033606461],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053492746,0.0005726548,0.000013282967,0.94166636,0.049229514,0.00075525325,0.00019961031,0.00002346979,0.0006682518,0.0003829012,0.00009275122,0.006342457],"study_design_scores_gemma":[0.0019796642,0.00029566052,0.000036124882,0.00934064,0.9157178,0.00042920394,0.000005762817,0.00006808595,0.00050194864,0.00012136138,0.069893695,0.0016100572],"about_ca_topic_score_codex":0.00003084705,"about_ca_topic_score_gemma":0.00013506658,"teacher_disagreement_score":0.9323257,"about_ca_system_score_codex":0.000032935615,"about_ca_system_score_gemma":0.000054148808,"threshold_uncertainty_score":0.9997614},"labels":[],"label_agreement":null},{"id":"W2626579659","doi":"10.1002/jnr.24098","title":"Quantitative profiling of neurotransmitter abnormalities in brain, cerebrospinal fluid, and serum of experimental diabetic encephalopathy male rat","year":2017,"lang":"en","type":"article","venue":"Journal of Neuroscience Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Streptozotocin; Cerebrospinal fluid; Central nervous system; Medicine; Internal medicine; Endocrinology; Encephalopathy; Serotonin; Neuroprotection; Diabetes mellitus; Neurotransmitter; Striatum; Intraperitoneal injection; Pharmacology; Dopamine; Receptor","score_opus":0.13500099771888643,"score_gpt":0.40757943859144397,"score_spread":0.27257844087255756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2626579659","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976219,0.00025725516,0.00003440385,0.0011378978,0.00026031476,0.0002395763,0.000009594372,0.0000029290934,0.00043615553],"genre_scores_gemma":[0.9992807,0.00021284977,0.00020748668,0.00015797818,0.000023780638,0.000004711293,3.8474244e-8,0.000012206388,0.000100270474],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99680525,0.00055741245,0.0005422704,0.0003481414,0.0012270854,0.00051984855],"domain_scores_gemma":[0.99828845,0.00061906374,0.00042173307,0.00031700564,0.00020426669,0.00014944951],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0016870119,0.00013921178,0.00033642745,0.00052905304,0.00035326916,0.00016247838,0.0010857902,0.000046803154,0.000019980089],"category_scores_gemma":[0.0034846053,0.00011563443,0.0000878625,0.00041588818,0.0027412504,0.0011217272,0.0002642989,0.00051239604,0.0000012202536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020427081,0.00018594562,0.022814563,0.000078908626,6.6967715e-7,0.00012309293,0.001047704,0.00001823824,0.97406054,0.0011385813,0.000027281712,0.00030022606],"study_design_scores_gemma":[0.00077523035,0.0018224263,0.12870125,0.00013799875,0.0000011825482,0.00015124414,0.001379727,0.0006659494,0.8659369,0.0003068456,0.000030194988,0.00009104909],"about_ca_topic_score_codex":0.000019596691,"about_ca_topic_score_gemma":0.0000033256829,"teacher_disagreement_score":0.10812362,"about_ca_system_score_codex":0.000025290528,"about_ca_system_score_gemma":0.000218778,"threshold_uncertainty_score":0.9999727},"labels":[],"label_agreement":null},{"id":"W2683873898","doi":"10.1016/j.bbi.2017.06.009","title":"Implications of the gut microbiota in vulnerability to the social avoidance effects of chronic social defeat in male mice","year":2017,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":97,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Douglas Mental Health University Institute; Royal Ottawa Mental Health Centre; McGill University; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Social defeat; Gut flora; Vulnerability (computing); Social vulnerability; Psychology; Social psychology; Developmental psychology; Biology; Immunology; Neuroscience; Psychological resilience; Computer security; Computer science","score_opus":0.027133895999739106,"score_gpt":0.3176619886119459,"score_spread":0.2905280926122068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2683873898","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955075,0.000050976207,0.0000036269178,0.0033723768,0.000088184184,0.00065581826,0.000051409042,0.0000050969993,0.00026502289],"genre_scores_gemma":[0.99954796,0.00000826835,0.000005627034,0.00024239784,0.00001906928,0.00006862112,9.2775633e-7,0.000007098107,0.0001000603],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988732,0.0004360294,0.00021011732,0.00019433605,0.000088297485,0.00019805366],"domain_scores_gemma":[0.9989868,0.00032316343,0.00014428345,0.00050525,0.000021868304,0.000018667904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033544295,0.000102143,0.00017253116,0.000038593676,0.00079233677,0.000032008662,0.0008000444,0.00007306675,0.000012291478],"category_scores_gemma":[0.00072529004,0.000073830655,0.00007522193,0.00019416388,0.0006275524,0.000085084364,0.0003315038,0.00029497195,0.0000015534763],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001745587,0.0002893273,0.03862122,0.000043128308,7.851241e-7,3.307383e-7,0.0022642715,5.477304e-7,0.95198,0.0002911644,0.00019925329,0.00629254],"study_design_scores_gemma":[0.0005257601,0.00002867523,0.8801132,0.00002116521,0.0000050641443,0.0000021529063,0.00012824891,0.0000014438384,0.11888116,0.000110959445,0.000113320595,0.00006887804],"about_ca_topic_score_codex":0.0008915385,"about_ca_topic_score_gemma":0.0027876752,"teacher_disagreement_score":0.84149194,"about_ca_system_score_codex":0.000057026165,"about_ca_system_score_gemma":0.00006734907,"threshold_uncertainty_score":0.6094094},"labels":[],"label_agreement":null},{"id":"W2704256164","doi":"10.1002/cpmo.27","title":"Monitoring Pathogen‐Induced Sickness in Mice and Rats","year":2017,"lang":"en","type":"article","venue":"Current Protocols in Mouse Biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Sickness behavior; Neurochemical; Pathogen; Immunology; Medicine; Psychology; Lipopolysaccharide; Internal medicine","score_opus":0.1321155039552236,"score_gpt":0.40476076569561864,"score_spread":0.27264526174039505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2704256164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.979206,0.000052888518,0.00000982813,0.00007632591,0.0003533064,0.020077266,0.000008831853,0.000034602846,0.00018091028],"genre_scores_gemma":[0.9675555,0.000040882183,0.000036126403,0.000025734038,0.00009120609,0.03221109,7.1165806e-7,0.000013066069,0.000025676449],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986113,0.00020288184,0.00024464648,0.0005101043,0.00006768677,0.0003634307],"domain_scores_gemma":[0.9993166,0.00010488832,0.00014177579,0.0003662642,0.000012386301,0.000058134112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002270295,0.00016137741,0.00021788877,0.0001170585,0.00015425,0.00008294823,0.00051784597,0.00011779499,0.000006346918],"category_scores_gemma":[0.0007559041,0.00014606028,0.000025609068,0.00007668783,0.00019852715,0.00017920861,0.00018681174,0.0002837025,0.00001466499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049384926,0.00012494477,0.082769126,0.00004797613,4.2906703e-7,0.000007926398,0.00016196477,5.36556e-7,0.8702264,0.00051851803,0.0000042030256,0.046088576],"study_design_scores_gemma":[0.0018176197,0.00012176463,0.06501575,0.00019477472,6.2190765e-7,0.0000038691046,0.0000429045,0.000041319385,0.92870444,0.0013754381,0.002415384,0.00026613154],"about_ca_topic_score_codex":0.00002132794,"about_ca_topic_score_gemma":0.000036895704,"teacher_disagreement_score":0.05847801,"about_ca_system_score_codex":0.000032299864,"about_ca_system_score_gemma":0.000039608847,"threshold_uncertainty_score":0.5956165},"labels":[],"label_agreement":null},{"id":"W2726396965","doi":"10.1080/13510002.2017.1343223","title":"Phytochemical treatments target kynurenine pathway induced oxidative stress","year":2017,"lang":"en","type":"review","venue":"Redox Report","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"Division of Graduate Education; University of Windsor","keywords":"Oxidative stress; Kynurenine pathway; Phytochemical; Kynurenine; Chemistry; Oxidative phosphorylation; Biology; Pharmacology; Traditional medicine; Biochemistry; Medicine; Tryptophan","score_opus":0.13858327023148093,"score_gpt":0.3862515189893313,"score_spread":0.24766824875785037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2726396965","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006641861,0.96605915,0.000010987639,0.000033050957,0.0009592029,0.0017421402,0.00035572817,0.00024266311,0.029932903],"genre_scores_gemma":[0.00094464235,0.98669094,0.00015462589,0.00003824895,0.00039417983,0.00033548466,0.0004558773,0.00012207395,0.010863952],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99620855,0.00019868449,0.0009491187,0.0014431255,0.0006232282,0.00057727215],"domain_scores_gemma":[0.9961426,0.00018993847,0.0016422169,0.001730963,0.00005287223,0.00024140946],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017776807,0.0007528545,0.0019318305,0.00017147549,0.00025856175,0.00014197423,0.0008919594,0.0005518522,0.00016553821],"category_scores_gemma":[0.0018786787,0.00057114806,0.00075735804,0.00025030642,0.0002020449,0.00018582254,0.0002610742,0.000631435,0.00021554957],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000129780365,0.00055550016,0.000011202751,0.00243349,0.00018794283,0.007439997,0.00006909404,9.90946e-8,0.005518169,0.00009368131,0.0017517238,0.98192614],"study_design_scores_gemma":[0.0003006504,0.000076462995,0.000008466246,0.003007538,0.00013474099,0.0011043794,0.0000057777743,7.205657e-7,0.038918994,0.00015268294,0.95569843,0.0005911727],"about_ca_topic_score_codex":0.000015124053,"about_ca_topic_score_gemma":0.0000017025436,"teacher_disagreement_score":0.9813349,"about_ca_system_score_codex":0.00016573542,"about_ca_system_score_gemma":0.00069245655,"threshold_uncertainty_score":0.999674},"labels":[],"label_agreement":null},{"id":"W2735065830","doi":"10.1016/j.physbeh.2017.07.018","title":"Exercise prevents IFN-α-induced mood and cognitive dysfunction and increases BDNF expression in the rat","year":2017,"lang":"en","type":"article","venue":"Physiology & Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"Behavioural despair test; Open field; Hippocampus; Prefrontal cortex; Brain-derived neurotrophic factor; Psychology; Treadmill; Hippocampal formation; Mood; Neurotrophic factors; Internal medicine; Aerobic exercise; Endocrinology; Neuroscience; Cognition; Medicine; Psychiatry; Antidepressant; Receptor","score_opus":0.03788532589976343,"score_gpt":0.3058657433216825,"score_spread":0.267980417421919,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2735065830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99914026,0.00006616369,7.8183416e-7,0.00006261993,0.000114935065,0.00046963803,0.000010260847,0.000019036606,0.00011631788],"genre_scores_gemma":[0.9994187,0.0001064898,0.0000055905293,0.00018422179,0.000028010827,0.00019395247,0.0000044594385,0.000009027834,0.00004955673],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99906665,0.00017536688,0.0001062314,0.0003771965,0.000090113004,0.00018444314],"domain_scores_gemma":[0.99943316,0.00016527843,0.00009834844,0.00024933074,0.000011197814,0.00004266883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007931424,0.00012953943,0.00015288533,0.000041712217,0.0004120396,0.000057520945,0.00019540201,0.00007743561,0.000020236841],"category_scores_gemma":[0.00022734494,0.000089947986,0.000025140382,0.00003712301,0.00026492297,0.00025293155,0.00014750795,0.00014945448,0.00000767076],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012738282,0.0002686611,0.012080159,0.000005217952,6.6813516e-7,0.000007621592,0.00034811534,2.9645358e-8,0.97304994,0.00001113754,0.000027577888,0.014073516],"study_design_scores_gemma":[0.00088853703,0.000083023675,0.7580887,0.000059654118,0.000021406942,0.0000069282405,0.00024562978,0.0000042982915,0.24028692,0.00022335006,0.0000061205196,0.000085439664],"about_ca_topic_score_codex":0.000084507046,"about_ca_topic_score_gemma":0.000033239183,"teacher_disagreement_score":0.7460085,"about_ca_system_score_codex":0.000004587115,"about_ca_system_score_gemma":0.00001154251,"threshold_uncertainty_score":0.36679724},"labels":[],"label_agreement":null},{"id":"W2736826461","doi":"10.1159/000470804","title":"Neuroprogression and Immune Activation in Major Depressive Disorder","year":2017,"lang":"en","type":"article","venue":"Modern trends in psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Translocator protein; Neuroscience; Glutamate receptor; Major depressive disorder; Psychology; Internal medicine; Orbitofrontal cortex; Endocrinology; Neuroinflammation; Medicine; Amygdala; Prefrontal cortex; Inflammation; Receptor","score_opus":0.01975050466906624,"score_gpt":0.2991663688827812,"score_spread":0.27941586421371495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2736826461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99064994,0.00034560222,0.00015262616,0.0029876276,0.0005729185,0.00011104519,0.00000386226,0.000041513485,0.005134867],"genre_scores_gemma":[0.999095,0.000042626518,0.00018841846,0.00024605947,0.000042257096,0.00002908288,0.000002940964,0.000025130588,0.0003284464],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9987329,0.000077034914,0.00022450076,0.00051141554,0.00017006548,0.00028403453],"domain_scores_gemma":[0.9992195,0.000038111317,0.00016682319,0.00052316487,0.0000058037867,0.00004664944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007070488,0.00016904993,0.00016379176,0.00028278993,0.0002976033,0.00012609301,0.00036717326,0.000096660275,0.00003875585],"category_scores_gemma":[0.0001257738,0.00015460147,0.000041172305,0.00016074076,0.00015219275,0.00042859017,0.00015419324,0.00026614728,0.0000050321755],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029310756,0.0006567457,0.34810704,0.000042199492,0.0000037128218,0.00001666096,0.0008334678,0.00008188014,0.06886231,0.0022897918,0.00021444305,0.5785986],"study_design_scores_gemma":[0.0031676225,0.00004559146,0.96977013,0.000104548955,0.000002422788,0.000004422827,0.00005479616,0.0038197844,0.006660486,0.01603873,0.00009923824,0.00023222346],"about_ca_topic_score_codex":0.00009255954,"about_ca_topic_score_gemma":0.0004353195,"teacher_disagreement_score":0.6216631,"about_ca_system_score_codex":0.000014415438,"about_ca_system_score_gemma":0.00001706662,"threshold_uncertainty_score":0.6304465},"labels":[],"label_agreement":null},{"id":"W2738173692","doi":"","title":"Subdural infusion of kynurenic acid causes myelin loss in chicken optic nerves","year":2017,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Waterloo","funders":"","keywords":"Kynurenic acid; Myelin; Anatomy; Medicine; Internal medicine; Central nervous system; Glutamate receptor","score_opus":0.06104266251935791,"score_gpt":0.3547644995032255,"score_spread":0.2937218369838676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2738173692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99660885,0.000053992375,7.35933e-7,0.0007077273,0.00038592337,0.0002929558,0.00001036651,0.000032397376,0.0019070524],"genre_scores_gemma":[0.99930954,0.00001073355,0.00029220775,0.00019331418,0.000032116208,0.000022928416,0.0000011725203,0.0000152444845,0.00012276192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99707425,0.00027746693,0.0004534167,0.00090818014,0.0005724919,0.00071420486],"domain_scores_gemma":[0.9982594,0.0002708552,0.0004763112,0.0006327279,0.00010373434,0.00025691674],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0007216183,0.00027642798,0.0003894119,0.0003482491,0.00078451587,0.00012947706,0.0019351742,0.00014049874,0.00011436182],"category_scores_gemma":[0.006918897,0.00023914978,0.00007831474,0.0008149711,0.016731678,0.0011400786,0.00073899206,0.00035491254,0.000061079605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003362188,0.00011964559,0.08506925,0.000014596553,0.0000017994428,0.00022789434,0.00093684637,0.00001840086,0.91227967,0.0011025907,0.000006069282,0.00018960293],"study_design_scores_gemma":[0.0003488005,0.00026173962,0.4186973,0.00004892941,0.0000020905222,0.00011218637,0.00011162721,0.00022428691,0.5744167,0.0056158346,0.0000028846541,0.0001576429],"about_ca_topic_score_codex":0.0003381917,"about_ca_topic_score_gemma":0.000047666206,"teacher_disagreement_score":0.337863,"about_ca_system_score_codex":0.00007121845,"about_ca_system_score_gemma":0.00045660054,"threshold_uncertainty_score":0.9859442},"labels":[],"label_agreement":null},{"id":"W2741228199","doi":"10.1158/1538-7445.am2017-ct116","title":"Abstract CT116: BMS-986205, an optimized indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, is well tolerated with potent pharmacodynamic (PD) activity, alone and in combination with nivolumab (nivo) in advanced cancers in a phase 1/2a trial","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of British Columbia; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Pharmacology; Nivolumab; Pharmacodynamics; In vivo; Pharmacokinetics; Adverse effect; Cancer; Cancer research; Internal medicine; Immunotherapy; Biology","score_opus":0.06802588785724402,"score_gpt":0.4034455019186154,"score_spread":0.3354196140613714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2741228199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99579287,0.00013982208,0.000013416772,0.00088301656,0.00012971694,0.0025659653,0.00006092931,0.00003744555,0.00037680712],"genre_scores_gemma":[0.99830306,0.00055377214,0.00005812703,0.00012414565,0.000056370827,0.0006302497,0.000012017309,0.000059857684,0.00020239763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99623257,0.00043095526,0.00039300806,0.0011059663,0.0009138951,0.00092357746],"domain_scores_gemma":[0.99858636,0.00019255345,0.00023343806,0.00058923685,0.0001377228,0.00026070004],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00085847714,0.00034306754,0.0005424563,0.00080564164,0.0003386842,0.00024553694,0.0005884177,0.0001416923,0.00011873917],"category_scores_gemma":[0.00020986203,0.00030392347,0.000033838693,0.0009866161,0.0006359458,0.0012746118,0.00015662776,0.001113918,0.0000055158525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.21003212,0.0026463824,0.00093285745,0.00013862422,0.00001662411,0.0007174668,0.0012415003,0.004430421,0.75183827,0.000008255294,0.00008288822,0.027914591],"study_design_scores_gemma":[0.34362248,0.002610754,0.023889918,0.0006020676,0.0000048712336,0.0000112656635,0.0005268381,0.021261077,0.6066787,0.000056425437,0.0000961599,0.00063942396],"about_ca_topic_score_codex":0.010006634,"about_ca_topic_score_gemma":0.02737657,"teacher_disagreement_score":0.14515956,"about_ca_system_score_codex":0.0009943204,"about_ca_system_score_gemma":0.0009426245,"threshold_uncertainty_score":0.9999413},"labels":[],"label_agreement":null},{"id":"W2743887053","doi":"10.1016/j.biopsych.2017.08.005","title":"Elevated Translocator Protein in Anterior Cingulate in Major Depression and a Role for Inflammation in Suicidal Thinking: A Positron Emission Tomography Study","year":2017,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":343,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; National Institute for Health and Care Research; European Commission; Ministère des relations internationales et de la Francophonie","keywords":"Translocator protein; Anterior cingulate cortex; Insula; Prefrontal cortex; Positron emission tomography; Internal medicine; Psychology; Cingulate cortex; Neuroinflammation; Microglia; Posterior cingulate; Inflammation; Major depressive disorder; Medicine; Neuroscience; Cortex (anatomy); Endocrinology; Cognition; Central nervous system","score_opus":0.020112884616899203,"score_gpt":0.2842704344189186,"score_spread":0.2641575498020194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2743887053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970522,0.00018466922,0.000022015725,0.0005982088,0.00010385057,0.001934895,0.00000503312,0.000042096184,0.00005706445],"genre_scores_gemma":[0.9993631,0.000007266029,0.0003226985,0.00008212192,0.000033110045,0.00017242452,0.0000023481743,0.000009921096,0.000007005003],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998492,0.00018269934,0.00036946093,0.00054200605,0.00011426176,0.00029955368],"domain_scores_gemma":[0.999516,0.000049767266,0.00014441501,0.00022595715,0.000008245593,0.000055592496],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003830899,0.0001718622,0.000244447,0.00022336983,0.00017865594,0.00008395521,0.00030872936,0.00018004098,0.0000050556764],"category_scores_gemma":[0.00026962665,0.00012526302,0.000052256106,0.00018368516,0.00008000549,0.00016047832,0.000068877656,0.00020142835,8.3079493e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078187924,0.00032054557,0.5025075,0.00002033507,9.9873e-7,0.0000041260523,0.00030733662,0.000001136711,0.49418017,0.00006398397,0.0000013777386,0.001810626],"study_design_scores_gemma":[0.004367158,0.00051053404,0.94765973,0.00018551471,0.000001735223,0.0000016319241,0.00028951117,0.000347581,0.04037252,0.0060747475,0.000010332156,0.0001790107],"about_ca_topic_score_codex":0.00012850114,"about_ca_topic_score_gemma":0.0010160655,"teacher_disagreement_score":0.45380765,"about_ca_system_score_codex":0.000016417456,"about_ca_system_score_gemma":0.000023616121,"threshold_uncertainty_score":0.51080775},"labels":[],"label_agreement":null},{"id":"W2745403759","doi":"10.1503/jpn160244","title":"Anti-inflammatory treatment and risk for depression","year":2017,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Depression (economics); Medicine; Internal medicine; Economics","score_opus":0.02644432369020318,"score_gpt":0.29538797584807047,"score_spread":0.2689436521578673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2745403759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99657416,0.0003868522,0.00032958912,0.00088955276,0.0015299409,0.00011976107,0.00000872779,0.0000074656045,0.00015395551],"genre_scores_gemma":[0.99608696,0.0029511284,0.00046003578,0.0002646572,0.00014548752,0.0000020028072,1.9509827e-8,0.0000068151517,0.00008287397],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99919635,0.000047894096,0.00020082764,0.0002503361,0.00013369182,0.00017092672],"domain_scores_gemma":[0.9990233,0.00010193161,0.0005115916,0.00020562376,0.000019170659,0.00013838075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020189141,0.00010835105,0.00015352403,0.00006745613,0.0009991671,0.00020922869,0.00028621798,0.00003455368,0.0000018360736],"category_scores_gemma":[0.0005338044,0.00007454193,0.00006680049,0.000034868764,0.00033682032,0.0004907966,0.000049304803,0.000098014134,4.452412e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021996698,0.00024265697,0.46534106,0.00004069751,0.0000035416542,0.000018643079,0.00015366465,0.000022775608,0.5093533,0.0017055288,0.00037617073,0.022522032],"study_design_scores_gemma":[0.002803921,0.0012360612,0.87126654,0.000073407165,0.000033826465,0.00043299573,0.00006952938,0.0005965091,0.11096199,0.0045079626,0.0078076334,0.00020965456],"about_ca_topic_score_codex":0.0000024714466,"about_ca_topic_score_gemma":0.0000064477317,"teacher_disagreement_score":0.40592545,"about_ca_system_score_codex":0.0000052230594,"about_ca_system_score_gemma":0.000064447755,"threshold_uncertainty_score":0.7684886},"labels":[],"label_agreement":null},{"id":"W2746779919","doi":"10.1111/bdi.12529","title":"Total sleep time and kynurenine metabolism associated with mood symptom severity in bipolar disorder","year":2017,"lang":"en","type":"article","venue":"Bipolar Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Military and Veteran Health Research","funders":"National Center for Advancing Translational Sciences; National Center for Research Resources; Joint Institute for Food Safety and Applied Nutrition, University of Maryland; National Institutes of Health; Georgia Clinical and Translational Science Alliance; University of Pennsylvania; Pennsylvania State University; U.S. Department of Veterans Affairs","keywords":"Neopterin; Bipolar disorder; Internal medicine; Actigraphy; Kynurenine; Mood; Major depressive disorder; Mania; Depression (economics); Sleep disorder; Body mass index; Medicine; Psychology; Psychiatry; Circadian rhythm; Insomnia","score_opus":0.007985676682380035,"score_gpt":0.22083128552445597,"score_spread":0.21284560884207593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2746779919","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906528,0.0061966088,0.000047547404,0.0011392826,0.00016630178,0.00055382814,0.00012302831,0.00018279145,0.000937793],"genre_scores_gemma":[0.9973322,0.0014470742,0.00007016695,0.00023285743,0.0000355412,0.000035075103,0.000022202772,0.000075602016,0.0007492795],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99732864,0.00022394996,0.00031979792,0.0008764716,0.00048131758,0.00076979987],"domain_scores_gemma":[0.99851424,0.00019966142,0.0002777235,0.00077238557,0.00003263342,0.0002033453],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027093137,0.00045479898,0.0004932428,0.00023458734,0.00077200396,0.00030834804,0.0006575636,0.0002165917,0.00015691269],"category_scores_gemma":[0.0012587265,0.00040119648,0.000108878594,0.00037668273,0.0006934684,0.00080629584,0.0002776985,0.00043429752,0.00006980347],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063697324,0.0028320001,0.6202939,0.000091847825,0.000260426,0.00006319641,0.002781163,0.0003077242,0.07407665,0.002595479,0.00046686802,0.29559374],"study_design_scores_gemma":[0.0042651366,0.00014685652,0.9641745,0.000047748348,0.000042388576,0.000013945425,0.00008193106,0.0031820566,0.0021644281,0.00063354615,0.02446416,0.00078327314],"about_ca_topic_score_codex":0.00071206014,"about_ca_topic_score_gemma":0.0043010986,"teacher_disagreement_score":0.3438806,"about_ca_system_score_codex":0.00003821464,"about_ca_system_score_gemma":0.00006200742,"threshold_uncertainty_score":0.999844},"labels":[],"label_agreement":null},{"id":"W2753033745","doi":"10.1016/j.bbi.2017.08.023","title":"Interaction between childhood maltreatment on immunogenetic risk in depression: Discovery and replication in clinical case-control samples","year":2017,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Medical Research Council; Institute of Psychiatry, Psychology and Neuroscience, King’s College London; Deutsche Forschungsgemeinschaft; King's College London; Flinders University; National Institute for Health and Care Research; Henry Luce Foundation; MQ: Transforming Mental Health; FP7 Health; South London and Maudsley NHS Foundation Trust; GlaxoSmithKline","keywords":"Replication (statistics); Depression (economics); Psychology; Early childhood; Psychiatry; Clinical psychology; Developmental psychology; Medicine; Virology","score_opus":0.05999621943974782,"score_gpt":0.3581543161560727,"score_spread":0.29815809671632487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2753033745","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99883413,0.00015234495,0.000015247755,0.00018938533,0.00008500848,0.0005379971,0.00008233183,0.000016783195,0.00008674649],"genre_scores_gemma":[0.99936193,0.00034643867,0.00002599409,0.00011938486,0.000028306791,0.00007343017,0.000008542338,0.000012149013,0.000023820647],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99834025,0.00055092224,0.00036308478,0.00047126086,0.00009161712,0.00018287967],"domain_scores_gemma":[0.9979374,0.0009145225,0.00022234846,0.00086030085,0.0000073257343,0.000058125705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005576798,0.00015341095,0.00022973288,0.00009747303,0.00045871397,0.00018253297,0.00018381454,0.00010484255,0.000008104749],"category_scores_gemma":[0.0015626205,0.0001332759,0.000051074734,0.00005152102,0.00018775271,0.0003605786,0.000121134806,0.00040610184,0.0000026620223],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000091894064,0.00038861495,0.7841963,0.0000030428887,0.000003063898,0.00004259425,0.00019889286,0.0000010388981,0.004058392,0.000013570184,0.0000042452216,0.21099834],"study_design_scores_gemma":[0.002667836,0.00021092713,0.99161947,0.000053483895,0.00002471833,0.000084696425,0.0001811619,0.000016224298,0.0048343176,0.00013386087,0.000037068825,0.00013623445],"about_ca_topic_score_codex":0.0016977136,"about_ca_topic_score_gemma":0.00047476945,"teacher_disagreement_score":0.2108621,"about_ca_system_score_codex":0.000033238317,"about_ca_system_score_gemma":0.00001797032,"threshold_uncertainty_score":0.5434834},"labels":[],"label_agreement":null},{"id":"W2754359204","doi":"10.1053/j.gastro.2017.09.002","title":"Indoleamine 2,3-Dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and Is Associated With Type II Hypersensitivity/Autoimmunity","year":2017,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre","funders":"National Institutes of Health; National Cancer Institute; University of Michigan Comprehensive Cancer Center; American Gastroenterological Association; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Autoimmunity; Indoleamine 2,3-dioxygenase; Inflammation; Metaplasia; Immunology; Medicine; Mucosal inflammation; Pathology; Biology; Immune system; Genetics","score_opus":0.016476337735414476,"score_gpt":0.24320972106565958,"score_spread":0.2267333833302451,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2754359204","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990542,0.000013438395,0.0000059105587,0.00036081267,0.000027095515,0.00033802967,0.000015896023,0.000029599796,0.00015501262],"genre_scores_gemma":[0.99961454,0.00001471765,0.000056236237,0.00022875301,0.000010666547,0.000013994705,0.000011851155,0.000015219497,0.00003403579],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99847245,0.00039179326,0.00023245392,0.0004014936,0.000119750526,0.00038203606],"domain_scores_gemma":[0.99929583,0.000112355934,0.00023048403,0.00026116663,0.00002969641,0.00007044814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003033503,0.00019314761,0.00032396198,0.0002618199,0.0002987526,0.00006346456,0.00017012237,0.00010088866,0.000010084607],"category_scores_gemma":[0.0008695298,0.00018145092,0.000017613684,0.00013495832,0.00037693026,0.00029002066,0.00020054204,0.0002987217,0.0000013736078],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00083796884,0.00027506647,0.29776797,0.000024170953,0.000018512957,0.00014098866,0.0011433942,0.000005686556,0.6987387,0.000024321449,0.000011318478,0.0010118948],"study_design_scores_gemma":[0.0037583406,0.0010536487,0.95261514,0.000051004627,0.000007744148,0.00013228325,0.00007817645,0.0005090501,0.04161112,0.0000768288,0.0000070235583,0.00009962047],"about_ca_topic_score_codex":0.00044181666,"about_ca_topic_score_gemma":0.005516264,"teacher_disagreement_score":0.65712756,"about_ca_system_score_codex":0.000036091977,"about_ca_system_score_gemma":0.000022930108,"threshold_uncertainty_score":0.7399354},"labels":[],"label_agreement":null},{"id":"W2754842155","doi":"10.1515/reveh-2017-0011","title":"Air pollution, aeroallergens and suicidality: a review of the effects of air pollution and aeroallergens on suicidal behavior and an exploration of possible mechanisms","year":2017,"lang":"en","type":"review","venue":"Reviews on Environmental Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Air pollution; Environmental science; Pollution; Environmental chemistry; Environmental health; Medicine; Chemistry; Ecology; Biology","score_opus":0.09713109372438365,"score_gpt":0.3663942619042612,"score_spread":0.26926316817987755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2754842155","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0027965538,0.99096864,0.000018396386,0.00039960994,0.00017993293,0.0053203376,0.000271704,0.000012116111,0.000032701766],"genre_scores_gemma":[0.020639315,0.97739255,0.00007503277,0.0015375499,0.000025357773,0.00018910816,0.000035116394,0.000045711837,0.00006024415],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9953915,0.0016239665,0.0013753815,0.00077700627,0.00049722346,0.0003349436],"domain_scores_gemma":[0.99635106,0.00012299021,0.002328475,0.00097193854,0.0000076898705,0.00021783831],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009941108,0.00054133777,0.0022991868,0.00013858844,0.00030667946,0.000009193248,0.0003416583,0.00019897905,0.000016074478],"category_scores_gemma":[0.0002640772,0.0003705232,0.00034485318,0.00017054619,0.0005012639,0.00026727174,0.00018305278,0.00030405412,0.0000047237677],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002411987,0.0007273393,0.000014996432,0.1659665,0.000021256155,0.0000018645487,0.00016824868,6.061971e-7,0.00095202535,0.0014977381,0.00015363471,0.8304717],"study_design_scores_gemma":[0.0027391803,0.009496753,0.013287655,0.3557218,0.0014354086,0.00015163171,0.00014420833,0.0000068077,0.0063560107,0.00060756545,0.60807055,0.0019824677],"about_ca_topic_score_codex":0.000056151774,"about_ca_topic_score_gemma":0.000035300316,"teacher_disagreement_score":0.8284892,"about_ca_system_score_codex":0.00014322472,"about_ca_system_score_gemma":0.00011536106,"threshold_uncertainty_score":0.99987465},"labels":[],"label_agreement":null},{"id":"W2755551966","doi":"10.1016/j.neubiorev.2017.09.014","title":"Major depressive disorder and anxiety disorders from the glial perspective: Etiological mechanisms, intervention and monitoring","year":2017,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; Concordia University; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Context (archaeology); Neuroscience; Etiology; Major depressive disorder; Anxiety; Perspective (graphical); Psychology; Intervention (counseling); Depression (economics); Psychiatry; Medicine; Cognition; Biology","score_opus":0.15961167799111806,"score_gpt":0.41823089809784714,"score_spread":0.2586192201067291,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2755551966","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021138245,0.9936743,0.00018227534,0.000047716556,0.0012762935,0.002392462,0.00016637283,0.00008509237,0.00006167206],"genre_scores_gemma":[0.004476332,0.99451256,0.000106656895,0.00016186664,0.000159632,0.00042985444,0.000008314582,0.000052429048,0.00009235237],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9952336,0.00087405107,0.0007837952,0.0020055298,0.00047330646,0.0006297473],"domain_scores_gemma":[0.9977089,0.00005247003,0.00097621966,0.0009982205,0.00003276662,0.00023143514],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.00057300983,0.0008186846,0.0014764594,0.00010452541,0.0014221004,0.0007917632,0.0015494971,0.00034778466,0.000042823605],"category_scores_gemma":[0.0022884812,0.00048818628,0.0006342336,0.00033309983,0.0015066906,0.00053023244,0.0009756071,0.00095165754,0.000027512033],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000065237737,0.00010381873,0.00029600615,0.00027512418,2.561212e-7,0.000007450783,0.00006316763,2.529184e-8,0.00070685544,0.0004112883,0.00005282436,0.9980767],"study_design_scores_gemma":[0.0003537412,0.00016021058,0.0019471827,0.0021604148,0.00024860818,0.000042805033,0.00010400243,0.0000048084808,0.000021919785,0.0008225609,0.99357843,0.00055529195],"about_ca_topic_score_codex":0.00032369446,"about_ca_topic_score_gemma":0.0000769194,"teacher_disagreement_score":0.99752134,"about_ca_system_score_codex":0.00007369092,"about_ca_system_score_gemma":0.000070586706,"threshold_uncertainty_score":0.9998779},"labels":[],"label_agreement":null},{"id":"W2755991345","doi":"10.1016/j.schres.2017.08.040","title":"Genetic variation in cytokine genes and risk for transition to psychosis among individuals at ultra-high risk","year":2017,"lang":"en","type":"letter","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Ministry of Science, ICT and Future Planning; Brain and Behavior Research Foundation","keywords":"Psychosis; Variation (astronomy); Genetic variation; Transition (genetics); Psychology; Gene; Genetics; Psychiatry; Clinical psychology; Medicine; Biology","score_opus":0.043612445925585996,"score_gpt":0.3217957965413222,"score_spread":0.2781833506157362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2755991345","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9376907,0.00019684,0.00033372827,0.056395162,0.00032367016,0.0026900382,0.0022142876,0.000057811743,0.000097799566],"genre_scores_gemma":[0.96409297,0.0055486383,0.0037957446,0.019000594,0.003476044,0.0023218575,0.00024048127,0.00027044202,0.0012532076],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9942774,0.0013879783,0.00047256358,0.0015611931,0.0012310422,0.0010698298],"domain_scores_gemma":[0.9968797,0.0015652725,0.0002778258,0.0009534465,0.0001337957,0.00018994544],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015114286,0.00041658696,0.0004848213,0.0012167826,0.0011124581,0.00047780882,0.0009482579,0.00079753477,0.000087410495],"category_scores_gemma":[0.0019673167,0.00040561552,0.00013872121,0.00055846537,0.00042355305,0.00022502904,0.00014434115,0.0020891842,0.00010044831],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004405106,0.00039965994,0.025373664,0.0011385621,0.00020376127,0.00032957035,0.0047057807,0.00040446187,0.14422745,0.00013750842,0.7201955,0.09847901],"study_design_scores_gemma":[0.008686186,0.0009858058,0.8388731,0.00039893133,0.00011262484,0.000026659813,0.000038735132,0.00048507546,0.039820775,0.016490338,0.09261962,0.0014621647],"about_ca_topic_score_codex":0.002037023,"about_ca_topic_score_gemma":0.0017861214,"teacher_disagreement_score":0.8134994,"about_ca_system_score_codex":0.00015939897,"about_ca_system_score_gemma":0.000108069406,"threshold_uncertainty_score":0.99983954},"labels":[],"label_agreement":null},{"id":"W2758455641","doi":"10.1186/s40364-017-0107-6","title":"Comparative study of two protocols for quantitative image-analysis of serotonin transporter clustering in lymphocytes, a putative biomarker of therapeutic efficacy in major depression","year":2017,"lang":"en","type":"article","venue":"Biomarker Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Saskatchewan Health Research Foundation","keywords":"Serotonin transporter; Biomarker; Serotonin; Depression (economics); Medicine; Cluster analysis; Bioinformatics; Pathology; Internal medicine; Biology; Computer science; Artificial intelligence; Genetics; Receptor","score_opus":0.3488978120343236,"score_gpt":0.5250300460882328,"score_spread":0.1761322340539092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2758455641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97787476,0.00004577044,0.0005963779,0.000035815014,0.000012666816,0.020999128,0.000101175225,0.000007100408,0.00032719114],"genre_scores_gemma":[0.9940243,0.0000037218829,0.0004517835,0.000004865392,0.0000017751756,0.0054601026,0.0000056480903,0.000020061349,0.000027748754],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9960896,0.0012429184,0.0008182738,0.00064521894,0.00075767655,0.00044631405],"domain_scores_gemma":[0.9966066,0.0019058567,0.00047933392,0.0006649543,0.00028172365,0.000061549545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002086728,0.00020605903,0.00085949403,0.0014976186,0.00015385312,0.000051646944,0.00084119145,0.00007247386,0.000042600754],"category_scores_gemma":[0.00059529045,0.00016860089,0.00018925825,0.0017002636,0.0008292768,0.00028321953,0.00018164694,0.00015417111,0.0000012979511],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0092789335,0.0041866223,0.07035251,0.00025577674,0.00041169958,0.000020196787,0.015845766,0.00014044889,0.89594686,0.0000698721,0.0000069617026,0.0034843255],"study_design_scores_gemma":[0.009392854,0.0005871516,0.6620211,0.00018097895,0.000045129116,3.325619e-7,0.0034610794,0.020634715,0.30343348,0.00010953094,0.000004525942,0.00012913303],"about_ca_topic_score_codex":0.001476539,"about_ca_topic_score_gemma":0.003237832,"teacher_disagreement_score":0.5925134,"about_ca_system_score_codex":0.00008161504,"about_ca_system_score_gemma":0.00015422112,"threshold_uncertainty_score":0.68753445},"labels":[],"label_agreement":null},{"id":"W2758746528","doi":"","title":"THE EFFECTS OF ACUTE PSYCHOLOGICAL STRESS ON ENZYMES REGULATING THE KYNURENINE PATHWAY","year":2014,"lang":"en","type":"article","venue":"Journal of undergraduate research in Alberta","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Kynurenine pathway; Kynurenine; Endocrinology; Internal medicine; Indoleamine 2,3-dioxygenase; Tumor necrosis factor alpha; Tryptophan; Corticosterone; Biology; Medicine; Biochemistry; Hormone","score_opus":0.046349313144767236,"score_gpt":0.36097994214738627,"score_spread":0.314630629002619,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2758746528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8388257,0.00024914634,0.00005239401,0.1551212,0.0005187722,0.00042061653,0.000001979307,0.000007441708,0.0048027663],"genre_scores_gemma":[0.99807036,0.00064945006,0.000029806704,0.00021091438,0.00012843234,0.0000070864075,2.1015589e-7,0.0000158101,0.00088794815],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995334,0.0021942805,0.0005071428,0.00023679118,0.0012009667,0.0005267701],"domain_scores_gemma":[0.9793767,0.019642597,0.000317659,0.0004333321,0.000115805386,0.00011392852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022631646,0.00014222873,0.00025212133,0.00020477787,0.00033650213,0.000111699024,0.0010929089,0.00007503235,0.0000029674102],"category_scores_gemma":[0.007652412,0.00006558451,0.00014947285,0.0007071172,0.00062971504,0.00010895112,0.0001316304,0.0010688383,0.000010552059],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013600102,0.0010438687,0.0010665647,0.00012988149,0.00009214292,0.00013064011,0.0004796228,0.00026750343,0.31216586,0.6128291,0.007275713,0.0631591],"study_design_scores_gemma":[0.003582849,0.0044125384,0.005600501,0.0008963115,0.000014139196,0.000152038,0.0001346189,0.0013195231,0.6507578,0.32782906,0.005055246,0.00024539026],"about_ca_topic_score_codex":0.00005525922,"about_ca_topic_score_gemma":0.00014005415,"teacher_disagreement_score":0.33859193,"about_ca_system_score_codex":0.00004271873,"about_ca_system_score_gemma":0.000057895086,"threshold_uncertainty_score":0.91612047},"labels":[],"label_agreement":null},{"id":"W2760959372","doi":"10.1111/bjd.16018","title":"Systemic retinoids and psychiatric disorders in patients with skin diseases: a multifactorial relationship","year":2017,"lang":"en","type":"letter","venue":"British Journal of Dermatology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Psychiatry; Dermatology","score_opus":0.008063970809050745,"score_gpt":0.22409785839275548,"score_spread":0.21603388758370473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2760959372","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9511069,0.0019170472,0.00004110249,0.04327513,0.0024945934,0.0006774179,0.00015439872,0.000028184402,0.00030523396],"genre_scores_gemma":[0.9894874,0.00035425363,0.000053530097,0.009366696,0.0006107266,0.0000095707255,0.000023189728,0.000051294006,0.00004333459],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.997412,0.00057545496,0.0007218014,0.00041332017,0.00046011372,0.00041727035],"domain_scores_gemma":[0.9978747,0.00051034085,0.0011743836,0.00025820825,0.00007800528,0.00010436805],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000697589,0.0002750969,0.00067554583,0.00044216472,0.00024383786,0.00020508483,0.00056454795,0.00057900255,0.000012049142],"category_scores_gemma":[0.0011374749,0.00027769763,0.00013382187,0.00016083643,0.00035247844,0.00034085754,0.00006217503,0.0019055736,0.0000063185257],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036946606,0.00027396035,0.7743036,0.00045163097,0.000032890177,0.0048018247,0.00014881534,0.0000031876393,0.000003571586,0.00002437703,0.21516363,0.00442304],"study_design_scores_gemma":[0.013353192,0.0002664944,0.92861,0.001235904,0.00011592686,0.023760358,0.000043522738,0.000008719928,0.000010668733,0.0010426231,0.030790795,0.00076174474],"about_ca_topic_score_codex":0.00004295214,"about_ca_topic_score_gemma":0.00008326558,"teacher_disagreement_score":0.18437283,"about_ca_system_score_codex":0.00005175771,"about_ca_system_score_gemma":0.00017621787,"threshold_uncertainty_score":0.9999675},"labels":[],"label_agreement":null},{"id":"W2765281173","doi":"10.1016/j.jalz.2017.07.729","title":"[P4–566]: ASSESSING THE IMPACT OF INFLAMMATION ON LIMBIC CIRCUITRY AND ITS ROLE IN DEPRESSION IN OLDER ADULTS","year":2017,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill Genome Centre; Douglas Mental Health University Institute; McGill University; Alzheimer Society of Canada","funders":"","keywords":"Amygdala; Depression (economics); Nucleus accumbens; Inflammation; Medicine; Limbic system; Cohort; Neuroscience; Major depressive disorder; Hippocampus; Psychology; Internal medicine; Central nervous system","score_opus":0.027735778988811775,"score_gpt":0.313067362653822,"score_spread":0.2853315836650102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765281173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936263,0.004182349,0.000002525644,0.000103827326,0.00006725331,0.0002888459,0.0000020425941,0.000011213914,0.0017156607],"genre_scores_gemma":[0.99983037,0.00006199735,0.000006190986,0.00005075582,0.000021116944,0.000015027987,0.0000013138872,0.000011561032,0.0000016721177],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99902874,0.000104849016,0.0002158911,0.00026618002,0.00017259429,0.00021175298],"domain_scores_gemma":[0.9993259,0.00010307078,0.00020429798,0.00031902688,0.000013769408,0.000033953125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001807283,0.000120157274,0.00012080687,0.00010218724,0.00017716728,0.00012400541,0.0002839761,0.00006110143,0.00003593482],"category_scores_gemma":[0.00017075519,0.00008622248,0.000042311494,0.000091800044,0.0000666904,0.00049806706,0.000101187354,0.00014416159,0.00000897417],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089400404,0.0002886033,0.2949013,0.00001404284,0.00015250393,0.000013094696,0.0022907949,0.00019553611,0.49067828,0.00025157936,0.00005792506,0.21106695],"study_design_scores_gemma":[0.00071031926,0.000026949265,0.73925734,0.00009670357,0.000044179014,0.0000013046285,0.000068372705,0.0017774389,0.25775823,0.00017668132,0.000006275714,0.00007617717],"about_ca_topic_score_codex":0.00022355723,"about_ca_topic_score_gemma":0.000096718075,"teacher_disagreement_score":0.44435605,"about_ca_system_score_codex":0.000005419934,"about_ca_system_score_gemma":0.000030644947,"threshold_uncertainty_score":0.35160506},"labels":[],"label_agreement":null},{"id":"W2765476329","doi":"10.1016/j.bbi.2017.07.064","title":"Modulation of innate immunity by amyloidogenic peptides: Systematic review of pattern recognition receptors and peptide aggregation state","year":2017,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Innate immune system; Inflammasome; Amyloid (mycology); TLR2; P3 peptide; Pattern recognition receptor; Receptor; Immune system; Biology; Inflammation; Cell biology; Chemistry; Immunology; Amyloid precursor protein; Biochemistry; Medicine; Alzheimer's disease; Disease; Internal medicine","score_opus":0.03440791633456309,"score_gpt":0.2830967086265231,"score_spread":0.24868879229196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765476329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99664766,0.0018547316,0.00005639971,0.00010423782,0.000073998,0.0009946238,0.00014294768,0.000023975394,0.000101438694],"genre_scores_gemma":[0.9913954,0.008158082,0.000032405253,0.00016585462,0.000004103002,0.000057866182,0.00006213494,0.000017529634,0.00010662338],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99813825,0.00061742065,0.00061110675,0.00023126043,0.00023611519,0.00016586097],"domain_scores_gemma":[0.99804384,0.00025956956,0.0009031596,0.0006227596,0.000108330125,0.00006231951],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00078794954,0.00018513773,0.00046145968,0.00008945755,0.00038317006,0.000061801205,0.00028637444,0.00007013687,0.000033797114],"category_scores_gemma":[0.0019922724,0.00017160022,0.00008182273,0.00010935226,0.0003653708,0.0004847585,0.00013861993,0.00019506947,0.0000033372742],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005222149,0.00041383778,0.007498042,0.08923104,0.000022970093,0.0000019537536,0.001738819,3.2970277e-7,0.81462634,0.000010066047,0.00025665437,0.08614773],"study_design_scores_gemma":[0.002516197,0.00059168105,0.47328866,0.080962025,0.00035474348,0.000050452258,0.00093023625,0.00019282996,0.43945307,0.0007850642,0.000028223936,0.0008468487],"about_ca_topic_score_codex":0.0006472255,"about_ca_topic_score_gemma":0.000035919744,"teacher_disagreement_score":0.4657906,"about_ca_system_score_codex":0.000021238133,"about_ca_system_score_gemma":0.000022893119,"threshold_uncertainty_score":0.6997654},"labels":[],"label_agreement":null},{"id":"W2765484555","doi":"10.1371/journal.pone.0186700","title":"Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":164,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Natural Science Foundation of China; National University of Singapore","keywords":"Fluoxetine; Antidepressant; Cytokine; Medicine; Internal medicine; Pharmacology; Peripheral; Proinflammatory cytokine; Endocrinology; Behavioural despair test; Depression (economics); Tumor necrosis factor alpha; Inflammation; Hippocampus; Serotonin; Receptor","score_opus":0.09731100857396742,"score_gpt":0.2828003029718687,"score_spread":0.1854892943979013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765484555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998843,0.00011654465,0.000010590487,0.00024257283,0.000010452657,0.00032781556,0.0000104684,0.000011577936,0.00042699216],"genre_scores_gemma":[0.9995134,0.00013574034,0.00017388708,0.000023493405,0.000031173502,0.000034645785,0.0000012047333,0.000007828733,0.00007863295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936354,0.000023337056,0.00016050159,0.00017503141,0.00017353198,0.00010408111],"domain_scores_gemma":[0.9994908,0.000025550107,0.00017270014,0.00026155944,0.000018926925,0.000030459703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007499256,0.00006784178,0.00014549556,0.000054558266,0.00004995391,0.00001189599,0.00014370236,0.000043701995,0.000012647573],"category_scores_gemma":[0.00025101713,0.00006267465,0.000014750263,0.000033334978,0.00012205904,0.00019576363,0.000069939575,0.000061555285,0.0000013328212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089799774,0.00029937996,0.005494229,0.000267378,0.0000017618535,0.0000027574588,0.00019136537,0.0000052246464,0.9923183,0.00014729098,0.0000025010158,0.0011800192],"study_design_scores_gemma":[0.00074849365,0.000112639114,0.01513403,0.00024395298,0.000005636175,5.734495e-7,0.000005403411,0.020085735,0.9634464,0.0001553245,0.000002590682,0.00005923192],"about_ca_topic_score_codex":0.000008773036,"about_ca_topic_score_gemma":0.0000835447,"teacher_disagreement_score":0.028871905,"about_ca_system_score_codex":0.000010736051,"about_ca_system_score_gemma":0.000043867596,"threshold_uncertainty_score":0.2555798},"labels":[],"label_agreement":null},{"id":"W2766503838","doi":"10.1001/jamapsychiatry.2017.3016","title":"Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations","year":2017,"lang":"en","type":"article","venue":"JAMA Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":247,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Cancer Epidemiology and Genetics, National Cancer Institute; National Institute of Mental Health; NHLBI Division of Intramural Research; Institute of Molecular and Cell Biology; Stanley Center for Psychiatric Research, Broad Institute; University of North Carolina at Chapel Hill; School of Medicine, Emory University; National Institutes of Health; Ministry of Cultural Affairs; H. Lundbeck A/S; Medical Research Council; Siemens Healthineers; Tartu Ülikool; Leids Universitair Medisch Centrum; Westfälische Wilhelms-Universität Münster; Dokuz Eylül Üniversitesi; Vetenskapsrådet; Novo Nordisk; University of Toronto; Nederlands Instituut voor Onderzoek van de Gezondheidszorg; Medizinische Fakultät der Albert-Ludwigs-Universität Freiburg; Region Hovedstaden; GGZ Drenthe; Institute of Genetics; Department of Psychiatry, University of Toronto; Universität Greifswald; GGZ Friesland; Statens Serum Institut; GGZ inGeest; Háskóli Íslands; Bundesministerium für Bildung und Forschung; Janssen Research and Development; ZonMw; Rijksuniversiteit Groningen; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Gentofte Hospital; Deutsche Forschungsgemeinschaft; Australian Research Council; Trinity College Dublin; Universiteit Leiden; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; University of Glasgow; Rheinische Friedrich-Wilhelms-Universität Bonn; Universitair Medisch Centrum Groningen; Università degli Studi di Trento; Newcastle University; Vrije Universiteit Amsterdam; Stiftelsen för Strategisk Forskning; University of Oxford; National Cancer Institute; Lundbeckfonden; University College London; Albert-Ludwigs-Universität Freiburg; King's College London; Aarhus Universitet; Massachusetts Institute of Technology; Universität Basel; QIMR Berghofer Medical Research Institute; South London and Maudsley NHS Foundation Trust; Virginia Commonwealth University; James Cook University; Cardiff University; University of Texas Southwestern Medical Center; University of Southern California; Foundation for the National Institutes of Health; Broad Institute; F. Hoffmann-La Roche; Queensland University of Technology; Brigham and Women's Hospital; Kaiser Permanente; Queensland Brain Institute; Karolinska Institutet; University of Queensland; Emory University; National Institute for Health and Care Research; Universidad de Granada; Rigshospitalet; Aarhus Universitetshospital; Dalhousie University; Universitätsmedizin Göttingen; GlaxoSmithKline; Centre for Cognitive Ageing and Cognitive Epidemiology; Washington University in St. Louis; European Commission; Wellcome Trust; National Science Foundation; Massachusetts General Hospital; Rivierduinen; Pfizer; McDonnell Center for Systems Neuroscience; University of California, San Diego; Johns Hopkins University; Chinese Society of Clinical Oncology; Amgen","keywords":"Depression (economics); Association (psychology); Obesity; Medicine; Genome-wide association study; Psychiatry; Psychology; Genetics; Biology; Internal medicine; Single-nucleotide polymorphism; Genotype; Gene; Psychotherapist","score_opus":0.006178756694654128,"score_gpt":0.23431330930875977,"score_spread":0.22813455261410565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766503838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941516,0.0006089829,0.000036902136,0.0021572576,0.00033893544,0.00017041208,0.000012897884,0.000036130543,0.0024868983],"genre_scores_gemma":[0.99764425,0.00005729621,0.0010866122,0.00019840915,0.00006260596,0.0000064321102,0.0000017482705,0.00001379108,0.0009288617],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99911135,0.0000711449,0.00016534065,0.00026401598,0.00021966768,0.00016849415],"domain_scores_gemma":[0.9991448,0.00006785065,0.00031191818,0.00039288183,0.000028974533,0.000053561882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007653017,0.00010914088,0.0001490676,0.00007009469,0.0004342531,0.00012907268,0.00024214656,0.0001424015,0.00004666468],"category_scores_gemma":[0.00025208356,0.00008667607,0.000044232995,0.0001018514,0.00012394701,0.00021869692,0.00006477373,0.0001743134,0.000009717013],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001850736,0.00018571343,0.962051,0.000030195048,0.000025164454,0.0000012622659,0.00018031673,0.000016396798,0.025873069,0.004766396,0.0017328323,0.0049525974],"study_design_scores_gemma":[0.001719104,0.000039938397,0.99190164,0.000042448675,0.000023574108,0.000013032575,0.000030313593,0.00006006618,0.0032769013,0.0025307331,0.00025200448,0.00011026692],"about_ca_topic_score_codex":0.000021707798,"about_ca_topic_score_gemma":0.0000701316,"teacher_disagreement_score":0.029850634,"about_ca_system_score_codex":0.00001215176,"about_ca_system_score_gemma":0.000041224066,"threshold_uncertainty_score":0.35345474},"labels":[],"label_agreement":null},{"id":"W2766584842","doi":"10.1016/j.jalz.2017.06.1895","title":"[P4–031]: ALZHEIMER'S DISEASE AS A DISORDER OF TRYPTOPHAN METABOLISM","year":2017,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Treventis (Canada); Krembil Foundation","funders":"","keywords":"Enzyme; Chemistry; Indole test; Biochemistry; Computational biology; Biology","score_opus":0.03594439675832115,"score_gpt":0.2945500160788071,"score_spread":0.2586056193204859,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766584842","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75781536,0.19820188,0.00022770581,0.0039792657,0.0028047797,0.0017470267,0.00020734331,0.00038449155,0.034632128],"genre_scores_gemma":[0.99795645,0.0003473779,0.00029719758,0.0010620053,0.00013745115,0.0000713535,0.000010180285,0.0000664823,0.0000515196],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972723,0.00014657002,0.0004883656,0.0008126503,0.0006278204,0.0006523033],"domain_scores_gemma":[0.99735856,0.0000986747,0.00048396658,0.0016203608,0.00006554723,0.00037289],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016923256,0.00039986442,0.00041521844,0.00014128776,0.0007666821,0.00023759146,0.00150012,0.000099513694,0.001203835],"category_scores_gemma":[0.0003654295,0.00037396164,0.0003187273,0.00016935864,0.00064367685,0.0007048051,0.00045725203,0.00019570737,0.00051493035],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001549741,0.0044608954,0.023532681,0.00006665747,0.019941183,0.00042902437,0.00221886,0.00009364578,0.26583225,0.19403349,0.015192606,0.47264898],"study_design_scores_gemma":[0.0035570476,0.0001439166,0.16805287,0.000044053042,0.01241185,0.000010656507,0.000112009344,0.00025529964,0.69410646,0.012005201,0.108117394,0.0011832209],"about_ca_topic_score_codex":0.0003357724,"about_ca_topic_score_gemma":0.000046981517,"teacher_disagreement_score":0.47146577,"about_ca_system_score_codex":0.0000021808335,"about_ca_system_score_gemma":0.00012828142,"threshold_uncertainty_score":0.99987125},"labels":[],"label_agreement":null},{"id":"W2766723179","doi":"10.1016/j.neuroscience.2017.10.023","title":"Anxiety- and Depressive-Like Behaviors are Associated with Altered Hippocampal Energy and Inflammatory Status in a Mouse Model of Crohn’s Disease","year":2017,"lang":"en","type":"article","venue":"Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":101,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Iran National Science Foundation","keywords":"Inflammatory bowel disease; Inflammation; Immunology; Mood disorders; Colitis; Immune system; Innate immune system; Anxiety; Disease; Medicine; Internal medicine; Psychiatry","score_opus":0.02367050940952795,"score_gpt":0.2488366841198263,"score_spread":0.22516617471029834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766723179","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9993743,0.000030019704,0.0000634029,0.00005157789,0.000079387915,0.00016296304,0.00010660049,0.000035627225,0.00009617722],"genre_scores_gemma":[0.9990132,0.00019356736,0.00001638973,0.0004821117,0.0000051369975,0.000023896198,6.3153635e-7,0.000018306688,0.0002467653],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982649,0.00008599336,0.00019019109,0.0006686113,0.00036850237,0.00042180176],"domain_scores_gemma":[0.99884117,0.00006454075,0.000310056,0.00046658303,0.00002988016,0.00028774756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000803517,0.0001871582,0.0001965875,0.000114892726,0.00035907226,0.00017871025,0.00041652482,0.000049743267,0.0000017158137],"category_scores_gemma":[0.0009382214,0.00016467237,0.00002476974,0.000121749494,0.0011994198,0.0006053676,0.00024957303,0.0001243692,1.4122851e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015511733,0.00017578443,0.5616523,0.000020065121,5.77914e-7,0.000081799175,0.0002477137,0.0007696793,0.43573612,0.00024128103,0.000016682083,0.00090289605],"study_design_scores_gemma":[0.0010580011,0.000048354384,0.9484081,0.000045592984,0.0000056075983,0.0000033510757,0.00002601791,0.022065178,0.027959956,0.00016065684,0.000016342643,0.00020282817],"about_ca_topic_score_codex":0.000059863625,"about_ca_topic_score_gemma":0.00031989257,"teacher_disagreement_score":0.40777618,"about_ca_system_score_codex":0.000020273183,"about_ca_system_score_gemma":0.00011892239,"threshold_uncertainty_score":0.67151445},"labels":[],"label_agreement":null},{"id":"W2766855729","doi":"10.3233/jpd-171240","title":"Is the Enzyme ACMSD a Novel Therapeutic Target in Parkinson’s Disease?","year":2017,"lang":"en","type":"review","venue":"Journal of Parkinson s Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Deafness and Other Communication Disorders; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institutes of Health; Alzheimer's Society; Brain and Behavior Research Foundation; Michael J. Fox Foundation for Parkinson's Research; Scottish Rite Charitable Foundation of Canada; U.S. Department of Defense","keywords":"Quinolinic acid; Parkinson's disease; Biology; Kynurenine pathway; Neurotoxin; Genetics; Pathogenesis; Enzyme; Somatic hypermutation; Gene; Cell biology; Biochemistry; Disease; Kynurenine; Tryptophan; Immunology; Medicine; Amino acid; Internal medicine","score_opus":0.13920484819121773,"score_gpt":0.3699734395271527,"score_spread":0.230768591335935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766855729","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018617438,0.99519175,0.00007025077,0.0017720461,0.0010709026,0.00093189446,0.00044496648,0.000026679596,0.00030531708],"genre_scores_gemma":[0.018128848,0.97754127,0.000037954913,0.0027850026,0.0006969501,0.00008353269,0.00000697195,0.0001190124,0.0006004564],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9949925,0.000742882,0.0014750694,0.0007841925,0.001244529,0.00076085236],"domain_scores_gemma":[0.9941439,0.0007998415,0.002543156,0.0014516823,0.00008939839,0.00097202853],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008265709,0.00080825447,0.0017917542,0.00054438197,0.0003848249,0.0004950133,0.0031075468,0.0002148344,0.0003308919],"category_scores_gemma":[0.001822421,0.00049453665,0.0020461443,0.00049194135,0.00042591506,0.00046904347,0.00025444417,0.0013038233,0.00013840744],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010715376,0.0028759353,0.0014827894,0.009399458,0.00034356533,0.002986328,0.0005493272,0.000031565094,0.000051448587,0.0008323951,0.021627247,0.9587484],"study_design_scores_gemma":[0.00093694136,0.000051366915,0.0049715764,0.0051405444,0.0004961134,0.000057708814,0.00002220728,0.000054287033,0.0000088023935,0.0009935915,0.9867147,0.0005521353],"about_ca_topic_score_codex":0.000006349274,"about_ca_topic_score_gemma":0.0000048985944,"teacher_disagreement_score":0.9650875,"about_ca_system_score_codex":0.00022732794,"about_ca_system_score_gemma":0.0019496476,"threshold_uncertainty_score":0.9997506},"labels":[],"label_agreement":null},{"id":"W2767440265","doi":"10.1038/s41593-017-0010-3","title":"Social stress induces neurovascular pathology promoting depression","year":2017,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1018,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Université Laval","funders":"National Center for Complementary and Integrative Health; National Institute of Mental Health","keywords":"Social defeat; Chronic stress; Inflammation; Blood–brain barrier; Nucleus accumbens; Pathology; Biology; Immunology; Medicine; Neuroscience; Central nervous system","score_opus":0.028587043371805714,"score_gpt":0.3155167024748673,"score_spread":0.28692965910306156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767440265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931171,0.000052823718,0.00003853582,0.0016273343,0.0015137063,0.00024226362,0.000011315651,0.00016022628,0.0032366887],"genre_scores_gemma":[0.99605757,0.000021689233,0.00003291586,0.0034938497,0.0002071642,0.000013579874,7.2070213e-7,0.000023998957,0.00014852146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972998,0.00020150305,0.00018604826,0.0010919581,0.00064786134,0.00057281647],"domain_scores_gemma":[0.9987245,0.00010172611,0.00028173605,0.00073658547,0.00003795369,0.00011750613],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00022500478,0.00022583129,0.00019677934,0.00010229391,0.002581949,0.0005163991,0.0019887548,0.0002939491,0.0000109470775],"category_scores_gemma":[0.0052463165,0.00019142509,0.00011322712,0.00023896807,0.0007994087,0.0007452837,0.00056993583,0.001060436,0.000017260749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010581062,0.00009214195,0.002874512,0.000014716825,2.6229338e-7,0.00023339847,0.00023941393,0.0000044847493,0.9853863,0.00087535323,0.00018190879,0.010086929],"study_design_scores_gemma":[0.00043107301,0.000057171113,0.24170133,0.000019488994,0.0000037867105,0.00009303751,0.000020623567,0.00029296914,0.75375575,0.0006898674,0.0026788719,0.00025600812],"about_ca_topic_score_codex":0.0000048579845,"about_ca_topic_score_gemma":0.000005238255,"teacher_disagreement_score":0.23882681,"about_ca_system_score_codex":0.000012451747,"about_ca_system_score_gemma":0.000054179556,"threshold_uncertainty_score":0.99871653},"labels":[],"label_agreement":null},{"id":"W2767482553","doi":"10.3389/fnmol.2017.00248","title":"Translational Identification of Transcriptional Signatures of Major Depression and Antidepressant Response","year":2017,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Infrastructures en Biologie Santé et Agronomie; Aix-Marseille Université","keywords":"Major depressive disorder; Antidepressant; Fluoxetine; Anterior cingulate cortex; Medicine; Microarray; Depression (economics); Bioinformatics; Internal medicine; Oncology; Anxiety; Psychology; Psychiatry; Biology; Gene; Cognition; Gene expression; Serotonin; Receptor; Genetics","score_opus":0.014162845915171167,"score_gpt":0.26334142297420915,"score_spread":0.24917857705903798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767482553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9530376,0.00033491317,0.04554545,0.00027079857,0.00041709826,0.00021087268,0.00005609283,0.000010827225,0.00011630417],"genre_scores_gemma":[0.99851567,0.00005973493,0.001254169,0.00011930897,0.0000039046863,0.0000066773887,0.0000011233521,0.000009079737,0.000030331143],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840766,0.00019184577,0.00032070177,0.00045510195,0.00045456958,0.0001701243],"domain_scores_gemma":[0.9992234,0.00006808773,0.00025827624,0.0003770894,0.000024326844,0.000048838374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003630146,0.0001088441,0.00016449142,0.00021661422,0.00018323438,0.000053926604,0.0005794046,0.000061171464,0.000003297854],"category_scores_gemma":[0.0010205845,0.000106770785,0.00004741431,0.00016159592,0.0009267945,0.0003495248,0.0000498922,0.00012000699,1.9491816e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003029458,0.00007054855,0.01077566,0.0000220555,6.779027e-7,0.0000149174575,0.00010577471,0.00042650112,0.98593765,0.001050101,0.00003150437,0.0012616742],"study_design_scores_gemma":[0.00041486332,0.000024570329,0.40172803,0.00001820279,0.0000026688492,0.0000038277867,0.000012925239,0.003465121,0.5926947,0.0014955925,0.00007142795,0.00006806517],"about_ca_topic_score_codex":0.00000712226,"about_ca_topic_score_gemma":0.0000010283246,"teacher_disagreement_score":0.39324293,"about_ca_system_score_codex":0.000005258275,"about_ca_system_score_gemma":0.000047779646,"threshold_uncertainty_score":0.43539864},"labels":[],"label_agreement":null},{"id":"W2767493640","doi":"10.3389/fimmu.2017.01374","title":"The Kynurenine Pathway As a Novel Link between Allergy and the Gut Microbiome","year":2017,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Microbiome; Kynurenine; Aryl hydrocarbon receptor; Immunology; Kynurenine pathway; Immune system; Immune tolerance; Biology; Indoleamine 2,3-dioxygenase; Metabolic pathway; Allergy; Signal transduction; Medicine; Cell biology; Bioinformatics; Transcription factor; Tryptophan; Metabolism; Genetics; Biochemistry","score_opus":0.04629885206468412,"score_gpt":0.29846675679162876,"score_spread":0.2521679047269446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767493640","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00001973043,0.9926392,0.00013107144,0.0016646027,0.0027207672,0.00090835436,0.000066845605,0.000041056377,0.0018084025],"genre_scores_gemma":[0.000044008673,0.99472654,0.00015730257,0.00017646047,0.00024071313,0.00016012296,0.00002323121,0.00005756265,0.0044140527],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99718505,0.0006762326,0.0006444807,0.00070929644,0.00013687268,0.0006480815],"domain_scores_gemma":[0.9970512,0.0010316714,0.00062039366,0.0012344762,0.000019091443,0.000043168657],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0005426177,0.0004921348,0.0015878099,0.0002523738,0.00070371764,0.00019555597,0.0023306136,0.0006062572,0.000011386005],"category_scores_gemma":[0.0012915805,0.00026444023,0.0003476045,0.00026114966,0.0033071938,0.000079930745,0.00063283613,0.0011056957,0.00006109892],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004944344,0.00001451396,0.000001679723,0.00016691531,0.00018503555,0.000011750746,0.00012920643,3.937058e-8,0.00009264432,0.0024116554,0.0021945639,0.9947426],"study_design_scores_gemma":[0.0014828809,0.000052498377,0.00003074266,0.0006221596,0.000046427278,0.00008616019,0.000054352182,0.0000017953257,0.000029437471,0.0016301048,0.9956666,0.0002968344],"about_ca_topic_score_codex":0.0000707279,"about_ca_topic_score_gemma":0.000028174236,"teacher_disagreement_score":0.99444574,"about_ca_system_score_codex":0.00007193402,"about_ca_system_score_gemma":0.00026784965,"threshold_uncertainty_score":0.9999808},"labels":[],"label_agreement":null},{"id":"W2769359877","doi":"10.2147/ndt.s144774","title":"Cytokines and depression in cancer patients and caregivers","year":2017,"lang":"en","type":"article","venue":"Neuropsychiatric Disease and Treatment","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Depression (economics); Internal medicine; Cancer; Psychological intervention; Biomarker; Oncology; Cytokine; Clinical psychology; Psychiatry","score_opus":0.01730091400919738,"score_gpt":0.26770831491955555,"score_spread":0.2504074009103582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769359877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99749863,0.0011412152,1.709257e-7,0.00040207326,0.0001861268,0.00024085563,0.00004460732,0.000016033879,0.00047029156],"genre_scores_gemma":[0.99440074,0.005234736,0.0000049208334,0.00018200802,0.000031610954,0.00003048262,0.0000013908632,0.000009672535,0.00010442073],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99926,0.00003083833,0.00007528855,0.0003981507,0.00008965796,0.00014602854],"domain_scores_gemma":[0.99956083,0.000031431053,0.00005621429,0.00017004822,0.000006875944,0.00017457876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000007983406,0.00013426856,0.000101551996,0.00006612079,0.00029064703,0.00009716729,0.000064353386,0.000018973169,0.0000056915524],"category_scores_gemma":[0.00005071903,0.000100215744,0.000019906887,0.00004241335,0.00009705642,0.00014456532,0.00006520512,0.000030630734,0.0000012760963],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015277199,0.0002846985,0.9456061,0.000017101342,0.0000036109261,0.000044645014,0.00015798675,0.0000011979239,0.00017243963,0.000056278237,0.00006867081,0.053434487],"study_design_scores_gemma":[0.0026566442,0.000109198074,0.9962667,0.000013600366,0.00002782334,8.880866e-7,0.000023453551,0.00005006935,0.0001812552,0.00014335793,0.0004247736,0.0001022242],"about_ca_topic_score_codex":0.00025330437,"about_ca_topic_score_gemma":0.00010507728,"teacher_disagreement_score":0.053332265,"about_ca_system_score_codex":0.000012239788,"about_ca_system_score_gemma":0.000019113604,"threshold_uncertainty_score":0.40866792},"labels":[],"label_agreement":null},{"id":"W2770633884","doi":"10.1016/j.schres.2017.11.023","title":"Cytokines dysregulation in schizophrenia: A systematic review of psychoneuroimmune relationship","year":2017,"lang":"en","type":"review","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":116,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Fundación Tatiana Pérez de Guzmán el Bueno","keywords":"Psychoneuroimmunology; Proinflammatory cytokine; Schizophrenia (object-oriented programming); Disease; Immune dysregulation; Cytokine; Psychology; Clinical psychology; Immune system; Critical appraisal; Medicine; Psychiatry; Immunology; Inflammation; Internal medicine; Pathology","score_opus":0.2932918891952701,"score_gpt":0.4673760010144214,"score_spread":0.1740841118191513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770633884","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000050432012,0.9909379,0.000003616545,0.00020859126,0.00033003482,0.006310581,0.000078880075,0.00008011562,0.0019998448],"genre_scores_gemma":[0.0009287757,0.9964808,0.00011446805,0.00003565984,0.00012679283,0.0010453846,0.00005607599,0.000136799,0.0010752288],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.98749876,0.0055137337,0.0026167238,0.0013592795,0.002098467,0.00091301446],"domain_scores_gemma":[0.9905121,0.0042453893,0.0015470528,0.0032276765,0.00028441436,0.00018338485],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0049876915,0.0006965487,0.004110437,0.0022858977,0.0005184709,0.0002236998,0.002960993,0.0005421121,0.00010220707],"category_scores_gemma":[0.029827172,0.000558987,0.00085800915,0.0031997273,0.0007372502,0.0004151119,0.0005324324,0.002412496,0.00068659865],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001013651,0.00013457616,0.0000012213336,0.9393726,0.000021352314,0.000041299114,0.00002403728,2.4844118e-7,0.000028063607,0.005484558,0.00036439576,0.054426257],"study_design_scores_gemma":[0.0010187846,0.000083793144,0.000080612954,0.97125876,0.00018409899,0.0000866852,0.0000076009014,0.000011279314,0.000028286417,0.0019396534,0.024773892,0.00052652473],"about_ca_topic_score_codex":0.00002972144,"about_ca_topic_score_gemma":0.00003929735,"teacher_disagreement_score":0.05389973,"about_ca_system_score_codex":0.00021062566,"about_ca_system_score_gemma":0.0010748067,"threshold_uncertainty_score":0.99988896},"labels":[],"label_agreement":null},{"id":"W2774146678","doi":"10.1002/dvdy.24612","title":"Maternal immune activation in neurodevelopmental disorders","year":2017,"lang":"en","type":"review","venue":"Developmental Dynamics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":161,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Biology; Immune system; Immunology; Neuroscience; Genetics","score_opus":0.05493680548464658,"score_gpt":0.3164222424203447,"score_spread":0.26148543693569815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2774146678","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013035493,0.9246844,0.00026043734,0.00018340553,0.0040264046,0.0052379197,0.00037129142,0.00060302764,0.051597614],"genre_scores_gemma":[0.0038184978,0.9934251,0.00041592593,0.00009242495,0.000027494705,0.00015523518,0.00030571406,0.00012588769,0.0016337268],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99699885,0.00015198866,0.00089020445,0.0009081053,0.00042784674,0.0006230289],"domain_scores_gemma":[0.99881554,0.00013772245,0.0005686513,0.00037114936,0.00000888415,0.000098077275],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016229544,0.0006814925,0.00110224,0.0005230447,0.00033318272,0.00024050153,0.0012198027,0.00032110023,0.00009710739],"category_scores_gemma":[0.00023800989,0.00065386505,0.00026911733,0.0003808957,0.0001922399,0.0004218392,0.00049823895,0.000638966,0.00036664543],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008756319,0.000089008216,0.00013151248,0.0013571513,0.00001343591,0.000025346057,0.00007549269,6.0367285e-7,0.000028896895,0.00043520445,0.000029217612,0.99780536],"study_design_scores_gemma":[0.0008738165,0.000028317298,0.0068343175,0.0066003487,0.000024609979,0.0001309855,0.00008291009,0.0001532729,0.00012599821,0.00036361837,0.98313594,0.001645873],"about_ca_topic_score_codex":0.000086713124,"about_ca_topic_score_gemma":0.00033023194,"teacher_disagreement_score":0.9961595,"about_ca_system_score_codex":0.0010095927,"about_ca_system_score_gemma":0.0005372586,"threshold_uncertainty_score":0.99959123},"labels":[],"label_agreement":null},{"id":"W2775178750","doi":"10.1017/s1092852917000803","title":"Peripheral levels of superoxide dismutase and glutathione peroxidase in youths in ultra-high risk for psychosis: a pilot study","year":2017,"lang":"en","type":"article","venue":"CNS Spectrums","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Superoxide dismutase; Glutathione peroxidase; Psychosis; Peroxidase; Peripheral; Medicine; Internal medicine; Chemistry; Psychiatry; Biochemistry; Enzyme; Oxidative stress","score_opus":0.046535466516813596,"score_gpt":0.30057348030560055,"score_spread":0.25403801378878693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2775178750","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976162,0.00005545715,0.00006513919,0.00047657258,0.00016195305,0.0010873553,0.0002471253,0.000028372382,0.00026187976],"genre_scores_gemma":[0.9994422,0.00005916944,0.000119669734,0.00012599463,0.000037410635,0.00010416661,0.0000014140454,0.000027312399,0.00008265765],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9982892,0.00013009264,0.0003622538,0.0006092483,0.00019963506,0.00040953603],"domain_scores_gemma":[0.9989743,0.00017077471,0.00016680194,0.0005776457,0.0000134845595,0.00009699873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003075467,0.00021966166,0.00035050453,0.00016086306,0.00023714408,0.00010683683,0.00043788177,0.000044519085,0.000045943347],"category_scores_gemma":[0.0009335129,0.00020094775,0.00005187438,0.00015270364,0.00029272697,0.00036615366,0.00006021533,0.00021373623,0.0000047739272],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020060309,0.007035918,0.3185556,0.0001198974,0.000028591898,0.00012565714,0.015448976,0.00007205792,0.6449814,0.004854694,0.00008467243,0.006686547],"study_design_scores_gemma":[0.008221893,0.0023527055,0.91548544,0.000060521656,0.0000138723835,0.000006584229,0.0029264423,0.00017128391,0.06689539,0.003530458,0.000018088132,0.00031734077],"about_ca_topic_score_codex":0.0011515896,"about_ca_topic_score_gemma":0.0036720952,"teacher_disagreement_score":0.59692985,"about_ca_system_score_codex":0.0000433694,"about_ca_system_score_gemma":0.000032464563,"threshold_uncertainty_score":0.81944114},"labels":[],"label_agreement":null},{"id":"W2775540375","doi":"10.1016/j.exger.2017.12.005","title":"The association between C-reactive protein, Interleukin-6 and depression among older adults in the community: A systematic review and meta-analysis","year":2017,"lang":"en","type":"review","venue":"Experimental Gerontology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":199,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"","keywords":"Depression (economics); Confounding; Cross-sectional study; Longitudinal study; Association (psychology); Medicine; C-reactive protein; Meta-analysis; Internal medicine; Gerontology; Inflammation; Psychology; Pathology","score_opus":0.15464291800603547,"score_gpt":0.4024258426430536,"score_spread":0.24778292463701812,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2775540375","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015445278,0.9930589,0.0000015920467,0.000116589246,0.000029399082,0.0048642857,0.000022994278,0.000015281556,0.0003464005],"genre_scores_gemma":[0.12567033,0.86993253,0.000005039652,0.0003102307,0.000015733032,0.0036979476,0.00001910747,0.000025128327,0.00032395762],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99175715,0.0065133106,0.00072480075,0.00045120425,0.00026506328,0.0002884415],"domain_scores_gemma":[0.995323,0.0023142754,0.0013942772,0.0008992697,0.00002154939,0.000047644535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014369541,0.00039622746,0.003498619,0.00011071254,0.0006381575,0.00018771077,0.0008937211,0.0002374968,0.000014248093],"category_scores_gemma":[0.0013245221,0.00018744521,0.0006309343,0.0001883247,0.00028854882,0.00016203211,0.0003183109,0.00071628485,0.000005947241],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053570086,0.0011547477,0.0005197983,0.82298774,0.09989373,0.00008899343,0.036846522,3.366178e-8,0.000037357357,0.00045061987,0.0005311687,0.03743571],"study_design_scores_gemma":[0.0018960652,0.000455265,0.00209328,0.10482516,0.85500443,0.00016906379,0.013465196,0.000006877418,0.0005873635,0.00011869856,0.019186955,0.002191635],"about_ca_topic_score_codex":0.00029527294,"about_ca_topic_score_gemma":0.00058282865,"teacher_disagreement_score":0.75511074,"about_ca_system_score_codex":0.00013157695,"about_ca_system_score_gemma":0.000021605516,"threshold_uncertainty_score":0.7643794},"labels":[],"label_agreement":null},{"id":"W2779378535","doi":"10.1007/978-3-319-67577-0_7","title":"Chemo-Immunotherapy: Role of Indoleamine 2,3-Dioxygenase in Defining Immunogenic Versus Tolerogenic Cell Death in the Tumor Microenvironment","year":2017,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute","keywords":"Indoleamine 2,3-dioxygenase; Immunotherapy; Tumor microenvironment; Cancer research; Immunology; Immune tolerance; Immune system; Biology; Medicine; Tryptophan","score_opus":0.07580324872885481,"score_gpt":0.37924889785294624,"score_spread":0.30344564912409144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2779378535","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11688053,0.88152194,2.6011983e-7,0.000015347328,0.00018115246,0.00053780735,0.000011344231,0.0000048598386,0.000846744],"genre_scores_gemma":[0.21483882,0.7847663,0.000028985152,0.00015590453,0.000030649157,0.00013570575,0.000019754785,0.000018107019,0.000005777226],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99793214,0.00033414108,0.0006915147,0.00055498333,0.000108998305,0.0003782279],"domain_scores_gemma":[0.9986097,0.0005122094,0.00041957144,0.00042535915,0.0000025084028,0.000030636613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002666642,0.00037630083,0.0011524995,0.00024706166,0.000056793542,0.0000066710327,0.0006809773,0.00014311394,0.00003469641],"category_scores_gemma":[0.00010033316,0.00023814244,0.000111715395,0.0001911477,0.00062558096,0.00009206719,0.00015265321,0.0003728222,0.000005526378],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005116158,0.0007592034,0.00025188582,0.00090457906,0.000020030015,0.00008630615,0.0023567614,0.0000015457099,0.23742753,0.00045608138,0.000005121787,0.7572193],"study_design_scores_gemma":[0.009825113,0.0024073634,0.00017343099,0.004402353,0.000024476192,0.00012941976,0.0053826733,0.000006309318,0.13879067,0.00022993024,0.8379065,0.0007218032],"about_ca_topic_score_codex":0.00009807415,"about_ca_topic_score_gemma":0.00005132251,"teacher_disagreement_score":0.83790135,"about_ca_system_score_codex":0.00009731775,"about_ca_system_score_gemma":0.00004420273,"threshold_uncertainty_score":0.9711167},"labels":[],"label_agreement":null},{"id":"W2779643662","doi":"10.1111/gbb.12446","title":"A role for activity‐dependent epigenetics in the development and treatment of major depressive disorder","year":2017,"lang":"en","type":"review","venue":"Genes Brain & Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Epigenome; Epigenetics; Epigenomics; DNA methylation; Major depressive disorder; Neuroscience; Histone; Antidepressant; Stressor; Psychology; Biology; Gene; Genetics; Cognition; Hippocampus; Gene expression","score_opus":0.11831530955601711,"score_gpt":0.37365266677803655,"score_spread":0.25533735722201945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2779643662","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06660128,0.9288857,0.0000322268,0.000057567217,0.00012295315,0.004018967,0.00021328455,0.000015863583,0.000052172894],"genre_scores_gemma":[0.0038198668,0.9904738,0.00035134962,0.000034247652,0.000054129177,0.004503546,0.000028059272,0.000064987136,0.0006699882],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979118,0.0002491094,0.0004740864,0.0006898474,0.0002763119,0.00039885385],"domain_scores_gemma":[0.99788684,0.0008777615,0.0004628295,0.0006866951,0.000020773838,0.000065116015],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017838806,0.00047112393,0.0009944502,0.00016979978,0.0002798693,0.00009465452,0.0006686416,0.00022456289,0.000011329168],"category_scores_gemma":[0.0001883322,0.00030802682,0.00027916871,0.00010988472,0.00017039143,0.000059859285,0.0001268449,0.0001107783,0.000006054199],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012709554,0.00057966565,0.0000880704,0.00054167863,0.000015512307,0.000014020816,0.0009507266,3.961484e-7,0.00067852484,0.000018809826,0.000008929374,0.99709094],"study_design_scores_gemma":[0.0012421559,0.0002306951,0.0021170569,0.00052038196,0.00030131557,0.000029190789,0.00016311296,0.0000019247748,0.0059790504,0.000018837665,0.9889436,0.00045267894],"about_ca_topic_score_codex":0.000039650276,"about_ca_topic_score_gemma":0.0006536714,"teacher_disagreement_score":0.9966383,"about_ca_system_score_codex":0.00007664872,"about_ca_system_score_gemma":0.00029328244,"threshold_uncertainty_score":0.9999372},"labels":[],"label_agreement":null},{"id":"W2781744373","doi":"10.1101/228742","title":"PET studies of the glial cell marker TSPO in psychosis patients - a meta-analysis using individual participant data","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Medical Research Council; National Institutes of Health; Vetenskapsrådet; King's College London; Stockholms Läns Landsting; National Institute for Health and Care Research; Maudsley Charity; Wellcome Trust; South London and Maudsley NHS Foundation Trust","keywords":"Translocator protein; Psychosis; Schizophrenia (object-oriented programming); Positron emission tomography; Temporal cortex; Medicine; Binding potential; Internal medicine; Prefrontal cortex; Hippocampus; Psychology; Endocrinology; Neuroscience; Oncology; Psychiatry; Inflammation; Cognition; Neuroinflammation","score_opus":0.24367942864305628,"score_gpt":0.342179838202786,"score_spread":0.09850040955972975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2781744373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99364054,0.0018301235,0.000018179975,0.00015088399,0.00083815225,0.0008105628,0.002655108,0.000049317056,0.0000071054465],"genre_scores_gemma":[0.9986412,0.00017825696,0.00071078044,0.00024436062,0.000058590118,0.00009830488,6.002691e-7,0.000062957115,0.000004963803],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99516404,0.0007268979,0.00091200386,0.001631423,0.00094774604,0.0006179138],"domain_scores_gemma":[0.99330986,0.0002544813,0.001382054,0.0046932935,0.0002302093,0.00013010479],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012268857,0.0005869264,0.0015848455,0.00043316526,0.00030857694,0.00024305556,0.0035262927,0.00021357642,0.00006270622],"category_scores_gemma":[0.0020734402,0.00044010134,0.00071915565,0.0010351336,0.0005153773,0.0002897427,0.00378092,0.0006542601,0.000008202934],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003766259,0.005005474,0.26572648,0.0020216333,0.11288332,0.00016113633,0.0008104946,0.0022866298,0.6083138,0.00024032795,0.0021689788,0.0000051096777],"study_design_scores_gemma":[0.0017802219,0.000059296384,0.59097165,0.00018507247,0.13722238,9.665728e-9,0.000049006867,0.0021069264,0.2653341,0.0000132127425,0.0006701137,0.0016080133],"about_ca_topic_score_codex":0.00016009099,"about_ca_topic_score_gemma":0.00006333392,"teacher_disagreement_score":0.34297967,"about_ca_system_score_codex":0.000060466784,"about_ca_system_score_gemma":0.00030176176,"threshold_uncertainty_score":0.9998051},"labels":[],"label_agreement":null},{"id":"W2782071752","doi":"10.1007/978-981-10-6577-4_4","title":"Diagnosis of Major Depressive Disorders: Clinical and Biological Perspectives","year":2017,"lang":"en","type":"book-chapter","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Major depressive disorder; Mental illness; Psychiatry; Mental health; DECIPHER; Medicine; Psychology; Clinical psychology; Bioinformatics; Cognition","score_opus":0.07632073670088586,"score_gpt":0.33194290256445336,"score_spread":0.2556221658635675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2782071752","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01770539,0.002952721,0.00003396277,0.0009660443,0.0002620802,0.0005672578,0.00012280374,0.000098353325,0.9772914],"genre_scores_gemma":[0.79541886,0.035389148,0.00015334376,0.0003697477,0.00018027854,0.00003259914,0.0000039901433,0.000050831775,0.16840118],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99832404,0.00006058319,0.00037197664,0.00085292384,0.00018722084,0.00020328541],"domain_scores_gemma":[0.9979581,0.0010279849,0.00035676348,0.00050908345,0.000034434663,0.000113627175],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000106997344,0.00030442627,0.00055537006,0.0000867308,0.00015587363,0.00004927328,0.00047737744,0.00045820628,0.0011843295],"category_scores_gemma":[0.0015011306,0.00022075747,0.00027815616,0.000009287547,0.0024680959,0.000091681315,0.00032975088,0.00036592266,0.000052680396],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020164458,0.00044723586,0.01928082,0.00008621807,0.00011858147,0.000052087664,0.0004954,1.7526627e-7,0.00046148011,0.86812824,0.0058009923,0.104927115],"study_design_scores_gemma":[0.00614605,0.0019189258,0.08292865,0.0006544848,0.00019243399,0.000039597115,0.0008280864,0.000020434623,0.007903773,0.6245198,0.2720815,0.002766222],"about_ca_topic_score_codex":0.000016013559,"about_ca_topic_score_gemma":0.000049689756,"teacher_disagreement_score":0.8088902,"about_ca_system_score_codex":0.000006477904,"about_ca_system_score_gemma":0.0000356429,"threshold_uncertainty_score":0.99972874},"labels":[],"label_agreement":null},{"id":"W2782484904","doi":"10.1016/j.pnpbp.2018.01.003","title":"Targeting cytokines in reduction of depressive symptoms: A comprehensive review","year":2018,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Medicine; Rheumatoid arthritis; Major depressive disorder; Depression (economics); Mood; Antidepressant; Clinical trial; Cytokine; Ankylosing spondylitis; Mood disorders; Psoriasis; Disease; Internal medicine; Immunology; Psychiatry; Anxiety","score_opus":0.05937582833323578,"score_gpt":0.3819381128992208,"score_spread":0.322562284565985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2782484904","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.018011518,0.9765977,7.218508e-7,0.00034627802,0.0025939168,0.0022390329,0.000044097185,0.0000724838,0.00009421946],"genre_scores_gemma":[0.0029525436,0.9944038,0.000100509904,0.0016196584,0.00034142233,0.0005167166,0.000022266118,0.000038118313,0.000004967329],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9945354,0.0017056214,0.0014485226,0.0015099965,0.00017804427,0.00062242534],"domain_scores_gemma":[0.99786615,0.0007083035,0.0009601203,0.00029576704,0.0000533265,0.0001163042],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030089435,0.0006668554,0.0020523337,0.00043470797,0.00009775235,0.0000170575,0.0007006997,0.0006698507,0.00010232877],"category_scores_gemma":[0.00031102527,0.00047570473,0.0003207043,0.001206235,0.0014822719,0.000099985795,0.00026596186,0.0011487369,0.000016674374],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008774244,0.0022278358,0.02566322,0.073834114,0.00011372836,0.00018210642,0.0000737013,0.0000011380306,0.00021982027,0.0004481893,0.0075544985,0.8888042],"study_design_scores_gemma":[0.005571278,0.0016344641,0.009474748,0.05414939,0.00040498184,0.000718393,0.000039726867,0.000020758596,0.000033686338,0.0018726141,0.9241972,0.0018827704],"about_ca_topic_score_codex":0.0000012313874,"about_ca_topic_score_gemma":7.7119637e-7,"teacher_disagreement_score":0.91664267,"about_ca_system_score_codex":0.000025259049,"about_ca_system_score_gemma":0.0001063162,"threshold_uncertainty_score":0.99976945},"labels":[],"label_agreement":null},{"id":"W2783265629","doi":"10.3390/v10010036","title":"Interferons: Reprogramming the Metabolic Network against Viral Infection","year":2018,"lang":"en","type":"review","venue":"Viruses","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; SAMHD1; Interferon; Viral replication; Immune system; Innate immune system; Reprogramming; Intrinsic immunity; Cell biology; Transcription factor; Virology; Virus; Immunology; Genetics; Gene; RNA","score_opus":0.1212620894779605,"score_gpt":0.3606021485271227,"score_spread":0.2393400590491622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2783265629","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001468134,0.9952717,0.000051813262,0.000013135759,0.0016066438,0.0007261989,0.000012286935,0.0002840339,0.0018873623],"genre_scores_gemma":[0.000094580064,0.99624544,0.00003700647,0.0017328347,0.001402085,0.00019107289,0.000005937979,0.000070678245,0.00022037922],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997558,0.0005989755,0.00047557478,0.0006730556,0.00021891341,0.00047551273],"domain_scores_gemma":[0.9983582,0.0004637666,0.00036233795,0.0007373148,0.000017526329,0.00006087794],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00034561055,0.00040868632,0.000745973,0.00011791281,0.00038606988,0.00025412807,0.0005937399,0.00020175081,0.000059180726],"category_scores_gemma":[0.0007459793,0.00024436947,0.0004721197,0.00075144024,0.00035185204,0.00019226833,0.00026018065,0.00045744368,0.0009125954],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000037342343,0.00003147771,0.000003378163,0.00040986133,0.000028468767,0.0000034699513,0.000045562127,0.0000014424761,0.00001225618,0.0008793087,0.0032770522,0.995304],"study_design_scores_gemma":[0.000063068845,0.00004418393,0.0000038568387,0.0017313666,0.000110529065,0.00001432799,0.0000039955935,0.0000030957322,0.00016205097,0.00016039566,0.99743193,0.0002711823],"about_ca_topic_score_codex":0.00003922549,"about_ca_topic_score_gemma":0.000038625465,"teacher_disagreement_score":0.9950328,"about_ca_system_score_codex":0.000041582938,"about_ca_system_score_gemma":0.00013722229,"threshold_uncertainty_score":0.9998653},"labels":[],"label_agreement":null},{"id":"W2784255252","doi":"10.1021/acsmedchemlett.7b00488","title":"Identification of Potent Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors Based on a Phenylimidazole Scaffold","year":2018,"lang":"en","type":"article","venue":"ACS Medicinal Chemistry Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Krembil Foundation; Canada Research Chairs","keywords":"Indoleamine 2,3-dioxygenase; Imidazole; Chemistry; Enzyme; Small molecule; Imine; Drug discovery; Structure–activity relationship; Stereochemistry; Pharmacology; Computational biology; Medicine; Cancer research; Biochemistry; Biology; Tryptophan; In vitro; Amino acid; Catalysis","score_opus":0.01382919952096973,"score_gpt":0.2402380601246662,"score_spread":0.22640886060369647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2784255252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935945,0.000015939902,0.00029523845,0.003947779,0.00023606882,0.00016044482,0.000015911697,0.00007504912,0.001659036],"genre_scores_gemma":[0.9924454,0.0000039980923,0.000025912057,0.006885251,0.00048940384,0.000016220993,0.000012319305,0.000023855107,0.000097622134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980118,0.000045735946,0.00042459724,0.00049837097,0.00069165026,0.00032780314],"domain_scores_gemma":[0.99890107,0.00014651688,0.00026111593,0.00049345783,0.00005408606,0.0001437544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022674298,0.00021756913,0.00020454125,0.00008621438,0.00011002685,0.000021704558,0.00038932147,0.00008622954,0.00011865358],"category_scores_gemma":[0.0004802351,0.00019911266,0.00008560503,0.00039927883,0.0005873877,0.000081898295,0.000042078118,0.0001843458,0.000047125963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000133839,0.00014898997,0.000054404692,0.000086235596,0.0000045494135,0.000022267746,0.00015864678,0.0000529458,0.9933658,0.000006397698,0.0045873458,0.0013785502],"study_design_scores_gemma":[0.0009976014,0.00006907121,0.0005728807,0.000114295035,0.000008347209,0.000010100185,0.00014250913,0.000714455,0.996762,0.00001733514,0.00040637676,0.00018507156],"about_ca_topic_score_codex":0.000009594998,"about_ca_topic_score_gemma":6.213528e-7,"teacher_disagreement_score":0.004180969,"about_ca_system_score_codex":0.00006339522,"about_ca_system_score_gemma":0.000051327705,"threshold_uncertainty_score":0.8119579},"labels":[],"label_agreement":null},{"id":"W2785126233","doi":"10.1176/appi.ajp.2017.16070759","title":"Role of Complex Epigenetic Switching in Tumor Necrosis Factor-α Upregulation in the Prefrontal Cortex of Suicide Subjects","year":2018,"lang":"en","type":"article","venue":"American Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Mental Health","keywords":"Prefrontal cortex; Epigenetics; Major depressive disorder; Tumor necrosis factor alpha; Proinflammatory cytokine; Dorsolateral prefrontal cortex; Biology; Medicine; Internal medicine; Psychiatry; Genetics; Gene; Inflammation; Amygdala","score_opus":0.01751796758503724,"score_gpt":0.2754120876574261,"score_spread":0.2578941200723888,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2785126233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99888426,0.0001016875,0.00012039954,0.00026795323,0.00017602598,0.00011794089,0.00000588088,0.0000032570758,0.00032259114],"genre_scores_gemma":[0.9985394,0.000012834934,0.001017299,0.0003467933,0.00006884768,0.0000010093408,2.977965e-7,0.000011668844,0.000001870598],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984525,0.00025473256,0.00061269343,0.00014755146,0.0003314918,0.00020103679],"domain_scores_gemma":[0.99871385,0.0001630009,0.0008558337,0.00018244806,0.000041383795,0.000043507778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022387001,0.00011337312,0.00030462365,0.00022661166,0.000037611935,0.000013008161,0.00041900072,0.000019340552,0.000040464874],"category_scores_gemma":[0.00010508015,0.00008514846,0.000103019265,0.0005995404,0.00034568863,0.00012192822,0.000024919958,0.00018625044,0.0000015857853],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022156478,0.00025498445,0.28842455,0.000012199234,0.000005853753,0.0000017791668,0.0032926078,0.00005065244,0.6988879,0.00024306562,0.000020294043,0.0085845515],"study_design_scores_gemma":[0.0006097957,0.00086751464,0.96952635,0.00008955435,0.000005701152,0.000031949905,0.004327362,0.00024770075,0.022094427,0.002105296,0.000011505502,0.00008283078],"about_ca_topic_score_codex":0.00044727593,"about_ca_topic_score_gemma":0.0012698703,"teacher_disagreement_score":0.6811018,"about_ca_system_score_codex":0.000023579314,"about_ca_system_score_gemma":0.00013229507,"threshold_uncertainty_score":0.34722534},"labels":[],"label_agreement":null},{"id":"W2785540442","doi":"10.1016/j.cmet.2018.01.004","title":"Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation","year":2018,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":289,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Novo Nordisk Fonden; European Research Council; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Svenska Sällskapet för Medicinsk Forskning; Wenner-Gren Stiftelserna; Wellcome Trust; Stichting af Jochnick Foundation; Karolinska Institutet; Familjen Erling-Perssons Stiftelse","keywords":"Kynurenic acid; Kynurenine; Adipose tissue; Kynurenine pathway; Energy homeostasis; Endocrinology; Internal medicine; Biology; Glucose homeostasis; Inflammation; White adipose tissue; Carbohydrate metabolism; Chemistry; Receptor; Biochemistry; Medicine; Insulin resistance; Glutamate receptor; Tryptophan","score_opus":0.011757902077614844,"score_gpt":0.2270526196710643,"score_spread":0.21529471759344945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2785540442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98830444,0.0068830177,0.00021588923,0.00042670366,0.00037378306,0.00011741414,0.000008886626,0.00008690129,0.0035829653],"genre_scores_gemma":[0.99577,0.001755886,0.00029931846,0.00046113678,0.000285556,0.0000092082155,0.0000024983929,0.000021877016,0.0013945523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892193,0.00009812056,0.00016701799,0.0004000366,0.00015691138,0.00025597683],"domain_scores_gemma":[0.9994688,0.000045186895,0.00008228462,0.00024707208,0.000029152403,0.0001275161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000091450114,0.00016214448,0.00017801904,0.00012198571,0.00017637308,0.00009419194,0.00013290881,0.00008635966,0.0000903952],"category_scores_gemma":[0.000106048006,0.00014673886,0.0000243219,0.00023408979,0.00026806677,0.00025075063,0.00009592013,0.00007067843,0.000051857332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001999714,0.000012747994,0.0000066266566,0.000012607999,0.000002717146,0.0000033150413,0.00045091295,2.8526298e-7,0.8342913,0.0045464896,0.00043712062,0.16021593],"study_design_scores_gemma":[0.0005281787,0.000036233156,0.0028769625,0.0000052296396,0.00001660344,0.000010599247,0.000033894812,0.00007463955,0.8405906,0.0029721817,0.15269846,0.0001564453],"about_ca_topic_score_codex":0.000020628184,"about_ca_topic_score_gemma":0.000022196968,"teacher_disagreement_score":0.16005948,"about_ca_system_score_codex":0.0000050279696,"about_ca_system_score_gemma":0.000016593473,"threshold_uncertainty_score":0.5983837},"labels":[],"label_agreement":null},{"id":"W2787403740","doi":"10.1016/j.xphs.2018.01.023","title":"The Safety and Tolerability of Topically Delivered Kynurenic Acid in Humans. A Phase 1 Randomized Double-Blind Clinical Trial","year":2018,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; WorkSafe Victoria","keywords":"Kynurenic acid; Tolerability; Pharmacology; Medicine; In vivo; Internal medicine; Adverse effect; Antagonist; Biology","score_opus":0.2088420921118444,"score_gpt":0.48391645200324224,"score_spread":0.27507435989139783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2787403740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99382806,0.0004128467,0.00022409952,0.0030036827,0.0008230962,0.00055876793,0.000001898652,0.000005433309,0.00114209],"genre_scores_gemma":[0.9980963,0.00093726063,0.00019996919,0.00045169814,0.00028958396,0.0000031604234,4.2951196e-8,0.0000030270446,0.00001898904],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9961298,0.0011131838,0.0015229518,0.00028858808,0.0006351624,0.00031033],"domain_scores_gemma":[0.9956451,0.0033952382,0.0005086436,0.00012737903,0.0001179175,0.00020569615],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.008542628,0.00012154819,0.0005942312,0.00008772611,0.00028781712,0.00009810628,0.0006608592,0.000075614,0.00016950755],"category_scores_gemma":[0.004473684,0.000064323496,0.00024995394,0.00045170324,0.005812548,0.00026236844,0.00010537203,0.000412539,0.0000025788577],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9491055,0.00069726753,0.00028994208,0.0000073906585,0.0000142413355,0.000007456916,0.00024544148,0.000002349827,0.013551064,0.0041704034,0.000048166024,0.03186076],"study_design_scores_gemma":[0.95345294,0.0020674688,0.0004586664,0.000032151696,0.000038891012,0.000018110584,0.000111277346,0.0014575162,0.03458462,0.004080762,0.0035752696,0.00012231467],"about_ca_topic_score_codex":0.000004860418,"about_ca_topic_score_gemma":0.000021989677,"teacher_disagreement_score":0.031738445,"about_ca_system_score_codex":0.00002103337,"about_ca_system_score_gemma":0.00021652662,"threshold_uncertainty_score":0.99689305},"labels":[],"label_agreement":null},{"id":"W2787897432","doi":"10.1016/s2215-0366(18)30048-8","title":"Association of translocator protein total distribution volume with duration of untreated major depressive disorder: a cross-sectional study","year":2018,"lang":"en","type":"article","venue":"The Lancet Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":238,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Azrieli Foundation; Canada Research Chairs; Health Canada; Government of Ontario","keywords":"Translocator protein; Cross-sectional study; Medicine; Major depressive disorder; Internal medicine; Inflammation; Pathology","score_opus":0.01205386630566018,"score_gpt":0.26256904770454703,"score_spread":0.25051518139888684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2787897432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965279,0.000026125312,0.0008496783,0.0010852324,0.0002204306,0.0008173874,0.00023002485,0.000052113963,0.00019108586],"genre_scores_gemma":[0.9992221,0.0000016584924,0.000056179106,0.000042727628,0.00025130864,0.00005975319,0.000023186823,0.000011863544,0.00033122755],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986519,0.00018618755,0.00031371458,0.00025771727,0.00038991604,0.00020057203],"domain_scores_gemma":[0.9991492,0.000049937033,0.00038966176,0.00026244417,0.00012430399,0.000024465198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023769251,0.00012040072,0.00019373954,0.000031130006,0.0002085824,0.000034633656,0.00020875786,0.00006710735,0.000070861635],"category_scores_gemma":[0.00014024109,0.00008160708,0.000052105606,0.0003931474,0.00020011423,0.00014477073,0.000018011415,0.0001250717,0.000011967046],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010657695,0.00058482005,0.971997,0.000035618403,0.00004596321,2.480542e-7,0.0004177531,0.00003462914,0.024584746,0.0007586119,0.0003569156,0.00011789653],"study_design_scores_gemma":[0.0032695336,0.0007129898,0.9675765,0.0000214621,0.000024458659,0.0000034229809,0.00016024998,0.00024149346,0.027320072,0.0005096449,0.00005449529,0.000105656545],"about_ca_topic_score_codex":0.00011512344,"about_ca_topic_score_gemma":0.00050958764,"teacher_disagreement_score":0.0044205096,"about_ca_system_score_codex":0.000034883156,"about_ca_system_score_gemma":0.00007686042,"threshold_uncertainty_score":0.33278403},"labels":[],"label_agreement":null},{"id":"W2789312859","doi":"10.1016/j.bbi.2018.03.004","title":"Complement component 3a receptor deficiency attenuates chronic stress-induced monocyte infiltration and depressive-like behavior","year":2018,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":121,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute of Mental Health; National Institutes of Health","keywords":"Proinflammatory cytokine; Chronic stress; Inflammation; Major depressive disorder; Immune system; Immunology; Social defeat; Knockout mouse; Monocyte; Receptor; Complement system; Cytokine; Medicine; Psychology; Neuroscience; Internal medicine; Amygdala","score_opus":0.051432098294665135,"score_gpt":0.30567926624542413,"score_spread":0.25424716795075897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2789312859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99786365,0.000237023,0.00004636763,0.00021911247,0.00030646374,0.0008529346,0.00012200122,0.00010890022,0.00024352683],"genre_scores_gemma":[0.9990516,0.0001155695,0.00008429198,0.0003355207,0.00006744966,0.00015879852,0.000060017555,0.000026744441,0.00010003125],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99810076,0.00028589362,0.00035377804,0.00052495656,0.000283794,0.0004508341],"domain_scores_gemma":[0.9989813,0.00019140642,0.00015869894,0.00044010195,0.000066048924,0.00016245773],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018771061,0.00029257516,0.0002460859,0.00012404498,0.00090448203,0.00017888652,0.0003069905,0.00010540994,0.00025189272],"category_scores_gemma":[0.00011311859,0.00027678465,0.000056345772,0.00021360707,0.00055411604,0.00033142857,0.00027021125,0.0002855549,0.00003060166],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034960667,0.00044172746,0.023987481,0.000020165136,0.000002707921,0.0000047565345,0.00065939693,3.2543875e-7,0.94672614,0.00021197417,0.00030389178,0.027606491],"study_design_scores_gemma":[0.0013619603,0.0006343849,0.57753134,0.000038565777,0.000038151516,0.000026472113,0.00042115184,0.0000654702,0.41843563,0.000026058413,0.0010662465,0.00035457296],"about_ca_topic_score_codex":0.0004561365,"about_ca_topic_score_gemma":0.0002405413,"teacher_disagreement_score":0.55354387,"about_ca_system_score_codex":0.00007347827,"about_ca_system_score_gemma":0.000059601836,"threshold_uncertainty_score":0.9999684},"labels":[],"label_agreement":null},{"id":"W2789944740","doi":"10.1002/hup.2652","title":"Serum levels of interleukin 6 in schizophrenic patients during treatment augmentation with sarcosine (results of the <scp>PULSAR</scp> study)","year":2018,"lang":"en","type":"article","venue":"Human Psychopharmacology Clinical and Experimental","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Sarcosine; Positive and Negative Syndrome Scale; Placebo; Internal medicine; Schizophrenia (object-oriented programming); Medicine; Tolerability; Psychology; Gastroenterology; Psychosis; Psychiatry; Adverse effect; Glycine; Chemistry","score_opus":0.056462792834141795,"score_gpt":0.3922525650532731,"score_spread":0.3357897722191313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2789944740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982227,0.00003935984,3.0917175e-7,0.00003998819,0.00043318188,0.00073937216,0.0000541471,0.000013685541,0.00045727604],"genre_scores_gemma":[0.99946445,0.000011095499,0.000019595102,0.0002240186,0.000060720926,0.00003596489,0.0000015413178,0.00001398988,0.00016864398],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980967,0.00032997006,0.00070119574,0.0004775302,0.00017810012,0.00021648484],"domain_scores_gemma":[0.999228,0.00018885927,0.00029280107,0.0001949692,0.0000262799,0.0000690801],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001383024,0.00018307894,0.00030636913,0.00009361784,0.00013688413,0.000009215662,0.00022723425,0.00006466076,0.00008435763],"category_scores_gemma":[0.000050981598,0.00012058804,0.00007662973,0.00020596899,0.0009264126,0.00009411835,0.00011187909,0.00013630588,0.000005393759],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042170696,0.0100313425,0.21296863,0.000015115606,0.000073688,0.000008462182,0.006256854,0.0000046291343,0.7643434,0.000043545508,0.00014344056,0.0018938129],"study_design_scores_gemma":[0.035921406,0.0038926739,0.50736713,0.000021356685,0.000012496205,0.0000015651102,0.0007937584,0.000011569933,0.45187253,0.000028823322,0.000034552413,0.000042151092],"about_ca_topic_score_codex":0.000018930717,"about_ca_topic_score_gemma":0.000066713554,"teacher_disagreement_score":0.31247088,"about_ca_system_score_codex":0.000035320387,"about_ca_system_score_gemma":0.000021522508,"threshold_uncertainty_score":0.49174377},"labels":[],"label_agreement":null},{"id":"W2790759623","doi":"10.1016/j.psyneuen.2018.01.024","title":"The relationship between inflammatory state and quantity of affective episodes in bipolar disorder","year":2018,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Bipolar disorder; Mania; Young Mania Rating Scale; Mood; Internal medicine; Psychology; Pathophysiology; Rating scale; Clinical psychology; Medicine; Psychiatry; Developmental psychology","score_opus":0.03951354153935616,"score_gpt":0.3095771377490837,"score_spread":0.27006359620972753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790759623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975571,0.00051951176,0.000089460824,0.00090176275,0.0002774033,0.00024878405,0.000010636454,0.00003391791,0.00036139032],"genre_scores_gemma":[0.9992706,0.00039429634,0.000018175617,0.00014387933,0.00003212711,0.000016533282,4.090144e-7,0.000014831755,0.00010910485],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983713,0.0005073465,0.00027551744,0.0003609872,0.000115279385,0.00036953748],"domain_scores_gemma":[0.9970854,0.0024303356,0.00012106869,0.000292946,0.000025863188,0.000044403598],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009280364,0.00012954153,0.00016637945,0.00017278381,0.00021852861,0.000018230754,0.00024884555,0.000030088651,0.000009816666],"category_scores_gemma":[0.0016257914,0.00010259918,0.000029853123,0.00039809555,0.0012269538,0.00011741765,0.000093032024,0.00025882554,0.000050524388],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006704222,0.000036386777,0.97014534,0.000012025454,0.0000032952453,0.0000064888227,0.00024356267,0.0000012033188,0.005674119,0.016273316,0.00009350141,0.007443723],"study_design_scores_gemma":[0.000614988,0.00018054075,0.97024,0.0000067841097,0.0000024328306,0.00001430775,0.000057209658,0.000015693213,0.00905467,0.0143130515,0.0054070693,0.00009326733],"about_ca_topic_score_codex":0.00007116984,"about_ca_topic_score_gemma":0.0008982868,"teacher_disagreement_score":0.0073504555,"about_ca_system_score_codex":0.000009016853,"about_ca_system_score_gemma":0.000019965084,"threshold_uncertainty_score":0.45207623},"labels":[],"label_agreement":null},{"id":"W2790903108","doi":"10.1016/j.brainresbull.2018.02.001","title":"Involvement of NO/NMDA-R pathway in the behavioral despair induced by amphetamine withdrawal","year":2018,"lang":"en","type":"article","venue":"Brain Research Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Tehran University of Medical Sciences and Health Services; Iran National Science Foundation","keywords":"NMDA receptor; Anhedonia; Amphetamine; Open field; Behavioural despair test; Psychology; Dysphoria; Pharmacology; Nitric oxide; Animal models of depression; Internal medicine; Hippocampus; Endocrinology; Antidepressant; Medicine; Anxiety; Psychiatry; Receptor; Dopamine","score_opus":0.09407956877588691,"score_gpt":0.35805074450398316,"score_spread":0.26397117572809625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790903108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9819904,0.00003486817,0.000012795991,0.011384594,0.00008489314,0.00081292656,0.000027371976,0.00003577445,0.005616395],"genre_scores_gemma":[0.9955562,0.000010291337,0.00008566029,0.0022422876,0.000108787804,0.00013101911,0.000007341379,0.00002652717,0.0018319233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995502,0.0014585025,0.00035743276,0.00055058155,0.0013350097,0.00079645624],"domain_scores_gemma":[0.99788064,0.0011427065,0.000080615675,0.00059659383,0.00018003612,0.00011943184],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0027407357,0.00018090513,0.0002005294,0.00024555213,0.00024511825,0.00008852746,0.0010956669,0.000109305816,0.0010622476],"category_scores_gemma":[0.00229349,0.0001315285,0.00006912819,0.00096287066,0.0010547563,0.000056890418,0.00028703382,0.0005624758,0.0006427461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001619309,0.0009314362,0.0003769864,0.000025885975,0.0000022455276,0.000020747902,0.0017404541,2.5252527e-7,0.8363872,0.0010234367,0.15538259,0.003946806],"study_design_scores_gemma":[0.0018546891,0.0022796923,0.004737803,0.00006874972,9.627717e-7,0.0000043764535,0.0017911496,0.000031633288,0.6488427,0.00035583155,0.3397756,0.00025679654],"about_ca_topic_score_codex":0.00074003934,"about_ca_topic_score_gemma":0.000339022,"teacher_disagreement_score":0.18754451,"about_ca_system_score_codex":0.00006142873,"about_ca_system_score_gemma":0.00014243224,"threshold_uncertainty_score":0.9998509},"labels":[],"label_agreement":null},{"id":"W2790995577","doi":"10.1016/j.jpsychires.2018.02.023","title":"Oxidative stress markers imbalance in late-life depression","year":2018,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":92,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Oxidative stress; TBARS; Internal medicine; Glutathione peroxidase; Glutathione reductase; Glutathione; Lipid peroxidation; Endocrinology; Population; Medicine; Psychology; Chemistry; Biochemistry; Superoxide dismutase; Enzyme","score_opus":0.057501071830494396,"score_gpt":0.38219965259981953,"score_spread":0.3246985807693251,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790995577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98564047,0.0004948422,0.000112729205,0.0015611203,0.0006091925,0.00016774183,0.000004203416,0.000008547887,0.011401154],"genre_scores_gemma":[0.99795914,0.00049274304,0.00046873826,0.00021519684,0.0004612954,0.000002851785,1.726886e-7,0.000015147797,0.0003846956],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9968959,0.0007357943,0.0004681014,0.00027229133,0.0011325235,0.00049536285],"domain_scores_gemma":[0.9984731,0.00058545737,0.00023389261,0.00023527347,0.00024944395,0.00022281273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016074353,0.00010855698,0.00019993416,0.0008733184,0.00017863432,0.00007930507,0.0007279543,0.000086290245,0.00027415046],"category_scores_gemma":[0.0021498692,0.00008228033,0.000084791944,0.0018195655,0.00030126362,0.00025253728,0.00010939017,0.0008343436,0.00009175764],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0062784585,0.0018783581,0.48650905,0.00018223461,0.000041461884,0.00039328844,0.0030945058,0.00023371886,0.32079643,0.0012625421,0.1510607,0.028269252],"study_design_scores_gemma":[0.0077218083,0.0028833346,0.787777,0.00040365182,0.000009925353,0.000070358685,0.002216331,0.0015768261,0.17217226,0.014780444,0.009838939,0.00054913235],"about_ca_topic_score_codex":0.000030033805,"about_ca_topic_score_gemma":0.00003557901,"teacher_disagreement_score":0.30126792,"about_ca_system_score_codex":0.000066231456,"about_ca_system_score_gemma":0.00030073937,"threshold_uncertainty_score":0.36248544},"labels":[],"label_agreement":null},{"id":"W2791892911","doi":"10.1161/jaha.117.008185","title":"Beneficial Pleiotropic Antidepressive Effects of Cardiovascular Disease Risk Factor Interventions in the Metabolic Syndrome","year":2018,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Natural Sciences and Engineering Research Council of Canada","keywords":"Medicine; Disease; Metabolic syndrome; Internal medicine; Psychological intervention; Depression (economics); Risk factor; Endothelial dysfunction; Vascular disease; Physical therapy; Obesity; Endocrinology; Psychiatry","score_opus":0.015641568232994885,"score_gpt":0.27212413747741726,"score_spread":0.25648256924442236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791892911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980879,0.0006822832,0.000097462835,0.0004966818,0.00040400538,0.00019260241,0.000023178396,0.000004593011,0.000011291498],"genre_scores_gemma":[0.99925953,0.00029096403,0.00002647734,0.00025695085,0.00014153995,0.0000034026202,9.455712e-8,0.000007662382,0.000013358112],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974275,0.0013570726,0.000331648,0.0001127265,0.0006094601,0.00016156386],"domain_scores_gemma":[0.99814856,0.00067082915,0.00080671,0.00024694533,0.000087351546,0.000039587296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005033831,0.00008335566,0.00039254487,0.00011147353,0.00012791445,0.000030337005,0.00034674813,0.000019955989,0.000006965464],"category_scores_gemma":[0.0046827216,0.000049549413,0.0008784432,0.000568271,0.00013342373,0.0001357033,0.00004465981,0.00022405274,0.000005031097],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018145151,0.0008203948,0.9488811,0.0000841515,0.000846774,0.00004099401,0.0028900285,0.0012255504,0.032118905,0.00018100989,0.0009524587,0.01177718],"study_design_scores_gemma":[0.00036595305,0.00017669737,0.9911047,0.00006920094,0.00017014418,0.000009827853,0.00008358816,0.000045442128,0.0070297993,0.00027766675,0.0006146946,0.00005227272],"about_ca_topic_score_codex":0.00014698351,"about_ca_topic_score_gemma":0.000016980048,"teacher_disagreement_score":0.04222361,"about_ca_system_score_codex":0.00006987659,"about_ca_system_score_gemma":0.000052787454,"threshold_uncertainty_score":0.5605993},"labels":[],"label_agreement":null},{"id":"W2792331271","doi":"10.1093/jcag/gwy008.295","title":"A294 ROLE OF MACROPHAGE IN GUT MICROBIOTA-BRAIN SIGNALING","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"","keywords":"Immune system; Gut–brain axis; Lipopolysaccharide; Gut flora; Dysbiosis; Liposome; Behavioural despair test; Pharmacology; Immunology; Medicine; Biology; Internal medicine; Biochemistry","score_opus":0.00773684200518109,"score_gpt":0.21892956915489034,"score_spread":0.21119272714970924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792331271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918951,0.000009661406,0.000007996735,0.007328824,0.00035170876,0.000069623864,0.000030640665,0.0000015305538,0.00030495998],"genre_scores_gemma":[0.99701804,0.0000032364626,0.00009476615,0.0026445137,0.000076013275,3.9812852e-7,2.7114768e-7,0.000007935291,0.00015484322],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99847174,0.00043820083,0.0004951035,0.00009618549,0.00019624736,0.00030250344],"domain_scores_gemma":[0.9984576,0.0001415513,0.0010463881,0.00011339959,0.00014528204,0.00009578742],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006902952,0.00007821645,0.00024873423,0.00030448972,0.000061483304,0.000011130662,0.00042321798,0.000092723036,0.00009639662],"category_scores_gemma":[0.0011770063,0.00006532435,0.00013501484,0.0002094297,0.00012212351,0.00007326913,0.00003083974,0.00022957203,0.000004172643],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012358019,0.000042533342,0.14475478,0.0000053242234,0.00001907404,0.0000051979687,0.00046388758,0.00009996131,0.85148853,0.00010385583,0.0027687862,0.00012446515],"study_design_scores_gemma":[0.004788728,0.0016967637,0.63984567,0.00014259457,0.00003431417,0.0001256287,0.0004347248,0.00023456277,0.34267887,0.0020301065,0.007835949,0.00015208738],"about_ca_topic_score_codex":0.0017466691,"about_ca_topic_score_gemma":0.20686316,"teacher_disagreement_score":0.5088097,"about_ca_system_score_codex":0.00041186006,"about_ca_system_score_gemma":0.00022108748,"threshold_uncertainty_score":0.8076095},"labels":[],"label_agreement":null},{"id":"W2792728053","doi":"10.1016/j.molmet.2018.01.018","title":"Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat","year":2018,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of British Columbia; Centre Hospitalier de l’Université de Montréal; Université du Québec à Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fonds de Recherche du Québec-Société et Culture","keywords":"Saturated fat; Nucleus accumbens; Endocrinology; Internal medicine; Inflammation; Hyperinsulinemia; Anhedonia; Medicine; Chemistry; Insulin resistance; Diabetes mellitus; Receptor; Cholesterol; Dopamine","score_opus":0.013189422726311724,"score_gpt":0.2585487115291265,"score_spread":0.2453592888028148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792728053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967981,0.0010432586,0.00045871644,0.00026423647,0.00034904646,0.00047882507,0.0001002227,0.00018048266,0.00032711698],"genre_scores_gemma":[0.99763554,0.00013775738,0.00031582962,0.0015566403,0.00015070659,0.000040932642,0.000066295026,0.00004765759,0.000048653885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99805737,0.00023262735,0.00029133089,0.000614225,0.0003682235,0.00043622006],"domain_scores_gemma":[0.9991094,0.00009484775,0.00018099716,0.00032807465,0.00012066686,0.00016603271],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000076726166,0.00029732613,0.00029882052,0.00014248147,0.00028471698,0.00018523239,0.00028771802,0.0001232972,0.000059953458],"category_scores_gemma":[0.00040940012,0.00027964593,0.00007678724,0.00044541806,0.00041093686,0.0003316678,0.00017960867,0.00021886195,0.000057012046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037313548,0.000046643523,0.00020404824,0.0000075840303,0.000012588922,0.00005356262,0.00084052444,0.0000046865207,0.99024785,0.00023337091,0.0004333151,0.00787851],"study_design_scores_gemma":[0.0010501083,0.000040064842,0.021036202,0.000015998747,0.000057451598,0.000018576044,0.00010225663,0.0010598312,0.9717304,0.000294537,0.0042463797,0.00034821124],"about_ca_topic_score_codex":0.00008432031,"about_ca_topic_score_gemma":0.000014339454,"teacher_disagreement_score":0.020832153,"about_ca_system_score_codex":0.000014602399,"about_ca_system_score_gemma":0.00001788613,"threshold_uncertainty_score":0.99996555},"labels":[],"label_agreement":null},{"id":"W2793970618","doi":"10.1016/j.biopsych.2018.01.017","title":"Opposite Molecular Signatures of Depression in Men and Women","year":2018,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":285,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health","keywords":"Major depressive disorder; Anterior cingulate cortex; Prefrontal cortex; Dorsolateral prefrontal cortex; Depression (economics); Psychology; Gene; Internal medicine; Amygdala; Clinical psychology; Endocrinology; Neuroscience; Medicine; Biology; Genetics; Cognition","score_opus":0.043731785979409285,"score_gpt":0.3216719071036338,"score_spread":0.2779401211242245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793970618","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010445313,0.9860704,0.0000046390173,0.000019072975,0.00021731018,0.0004183315,0.000026729867,0.000031408057,0.0027668003],"genre_scores_gemma":[0.008425496,0.99095553,0.00017731746,0.00027768392,0.00006272429,0.00004709769,0.000006377163,0.00001605803,0.000031733023],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982488,0.00034662324,0.00037898892,0.0006212045,0.00011614081,0.00028822146],"domain_scores_gemma":[0.9992954,0.00015738524,0.000204551,0.0002489703,0.000006707528,0.000086954846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015145075,0.00027089228,0.0007673666,0.00012996979,0.000033593602,0.000014880175,0.00038340027,0.000508937,0.00005976455],"category_scores_gemma":[0.00019005695,0.00016281195,0.00014965356,0.0002831805,0.00025559252,0.000026007829,0.00018360182,0.0002905348,0.000014431419],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023491628,0.0010298489,0.0015598107,0.012543933,0.00006488685,0.000051757685,0.00021680695,7.334556e-7,0.007898396,0.005001526,0.004475898,0.9669215],"study_design_scores_gemma":[0.0012539732,0.000966484,0.0024861067,0.008758697,0.000051496005,0.0000387112,0.00010346905,0.00000583199,0.000505118,0.011354095,0.9732182,0.0012578446],"about_ca_topic_score_codex":0.0000016604603,"about_ca_topic_score_gemma":5.084022e-7,"teacher_disagreement_score":0.96874225,"about_ca_system_score_codex":0.000018393592,"about_ca_system_score_gemma":0.000053847856,"threshold_uncertainty_score":0.66392785},"labels":[],"label_agreement":null},{"id":"W2794553725","doi":"10.1093/schbul/sby016.322","title":"T46. TARGETING THE IMMUNE SYSTEM TO TREAT DEPRESSION AND NEGATIVE SYMPTOMS IN SCHIZOPHRENIA","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Apathy; Anhedonia; Schizophrenia (object-oriented programming); Depression (economics); Minocycline; Psychiatry; Antipsychotic; Psychology; Psychosis; Medicine; Clinical psychology; Cognition","score_opus":0.009015166385551249,"score_gpt":0.23132378011336893,"score_spread":0.22230861372781768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794553725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99090946,0.0006212721,0.000067644774,0.002624831,0.000387487,0.00075687194,0.000016772614,0.0002258983,0.004389767],"genre_scores_gemma":[0.9974746,0.000022480643,0.0010409761,0.0006158959,0.00031457958,0.00009713209,0.0000019868783,0.00005120181,0.0003811131],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99722564,0.00044026677,0.00046961472,0.0008717327,0.00037404496,0.0006186704],"domain_scores_gemma":[0.99855304,0.00053979584,0.00015137858,0.0005197782,0.000050964285,0.00018505036],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00043091632,0.00036081055,0.0003448361,0.0002168269,0.00061039923,0.00018825778,0.00059752073,0.0001289539,0.00022343463],"category_scores_gemma":[0.0010126539,0.00025148707,0.0000804912,0.00069984084,0.00040794408,0.00009577204,0.00039401543,0.0003731459,0.00093420455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012053734,0.00031336382,0.0017504103,0.00022655465,0.000029042543,0.00012613162,0.006054035,0.0001049793,0.85513103,0.022272833,0.010438579,0.091499306],"study_design_scores_gemma":[0.009439414,0.0005099065,0.02408379,0.0007547851,0.000026843065,0.00010937319,0.0019136362,0.00089738745,0.94700974,0.0007745958,0.013394306,0.0010862477],"about_ca_topic_score_codex":0.00020103833,"about_ca_topic_score_gemma":0.00005550658,"teacher_disagreement_score":0.09187869,"about_ca_system_score_codex":0.00006985339,"about_ca_system_score_gemma":0.00004669645,"threshold_uncertainty_score":0.99999374},"labels":[],"label_agreement":null},{"id":"W2794645689","doi":"10.1016/j.neubiorev.2018.03.023","title":"Kynurenine pathway in depression: A systematic review and meta-analysis","year":2018,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":287,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Japan Agency for Medical Research and Development","keywords":"Kynurenine; Kynurenic acid; Quinolinic acid; Kynurenine pathway; Antidepressant; Depression (economics); Meta-analysis; Metabolite; Internal medicine; Medicine; Pharmacology; Endocrinology; Psychology; Tryptophan; Chemistry; Biochemistry; Glutamate receptor; Receptor; Hippocampus; Amino acid","score_opus":0.2809781901019265,"score_gpt":0.4165886385755081,"score_spread":0.1356104484735816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794645689","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000024492874,0.99169075,0.000013725348,0.0000113432625,0.00016268421,0.0077892686,0.00013595448,0.000087294466,0.000106503816],"genre_scores_gemma":[0.000022524695,0.99275,0.0000662478,0.0037594547,0.00002260031,0.0026115712,0.000012109584,0.00006616141,0.0006893214],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.99049515,0.0021514671,0.0029827962,0.0026280896,0.00087849854,0.0008640304],"domain_scores_gemma":[0.9954022,0.00004315221,0.002005185,0.0021118482,0.00005041835,0.000387151],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0021227961,0.0012970023,0.013475558,0.0009117819,0.00024084089,0.0002852831,0.0019518441,0.00031596122,0.00042074508],"category_scores_gemma":[0.0029693025,0.0007507272,0.0040705106,0.006693065,0.00067816174,0.00042945953,0.00054352847,0.0007371153,0.00024682572],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000014914091,0.00029598761,0.0000023598643,0.902355,0.000041210373,0.00013297213,0.000031936088,5.8267094e-8,0.00008030908,0.000043940327,0.0008723767,0.09614232],"study_design_scores_gemma":[0.000054320215,0.00006306212,0.000001487986,0.028310105,0.22245671,0.000105958716,0.0000014844088,0.0000014856051,0.0000059613044,0.0000046653317,0.7483938,0.00060098694],"about_ca_topic_score_codex":0.000013130309,"about_ca_topic_score_gemma":0.000031793617,"teacher_disagreement_score":0.87404495,"about_ca_system_score_codex":0.00007461356,"about_ca_system_score_gemma":0.00016686281,"threshold_uncertainty_score":0.9999782},"labels":[],"label_agreement":null},{"id":"W2794650984","doi":"10.1093/schbul/sby014.022","title":"7. RETINAL FUNCTIONS EXPRESSED IN RETINAL IMAGING, CONTRAST PROCESSING AND ELECTRORETINOGRAPHY MAY DECRYPT EARLY RISK MECHANISMS AND PATHOPHYSIOLOGY OF SCHIZOPHRENIA AND MOOD DISORDERS AND ACCELERATE TRANSLATION TO THE CLINIC","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre intégré universitaire de santé et de services sociaux de la Capitale-Nationale; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean","funders":"","keywords":"Schizophrenia (object-oriented programming); Mood disorders; Neuroscience; Psychology; Electroretinography; Retinal; Retina; Bipolar disorder; Mood; Psychiatry; Medicine; Ophthalmology; Anxiety","score_opus":0.010784986347224227,"score_gpt":0.23932822989298502,"score_spread":0.2285432435457608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794650984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926856,0.0006529125,0.002194832,0.0032804105,0.000060206694,0.0006107671,0.000033305525,0.00006113073,0.00042082003],"genre_scores_gemma":[0.994827,0.0005979678,0.0041330727,0.00025686008,0.0000554832,0.00005261083,0.0000025081424,0.000043561166,0.000030983058],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99780995,0.00039708332,0.00039771848,0.00078967307,0.00018491474,0.00042068807],"domain_scores_gemma":[0.99909514,0.00027517742,0.00022404386,0.0002158237,0.000043666612,0.00014612786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042118522,0.00029456776,0.00032560932,0.00026698504,0.00041654395,0.0001343793,0.00016532661,0.000103761085,0.00009136566],"category_scores_gemma":[0.00026515094,0.00024076166,0.00004332642,0.0003796411,0.00091647636,0.000104618644,0.00009651094,0.0003527758,0.000010292258],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01024228,0.0002014086,0.016619628,0.00012316873,0.000024236639,0.0000050721537,0.0037187575,0.0000026324087,0.7369863,0.0021217726,0.00044825624,0.22950651],"study_design_scores_gemma":[0.017482808,0.0032958009,0.8725275,0.00047504192,0.00016363357,0.00007497467,0.0015818767,0.0023094704,0.041288406,0.055435017,0.0038513148,0.0015141533],"about_ca_topic_score_codex":0.00007925579,"about_ca_topic_score_gemma":0.000287062,"teacher_disagreement_score":0.85590786,"about_ca_system_score_codex":0.000005046911,"about_ca_system_score_gemma":0.000033570035,"threshold_uncertainty_score":0.9817976},"labels":[],"label_agreement":null},{"id":"W2794682159","doi":"10.1093/schbul/sby016.400","title":"T124. CLINICAL DIFFERENCES BETWEEN URBAN AND RURAL SCHIZOPHRENIA","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Urbanity; Psychopathology; Medicine; Psychiatry; Disease; Rural area; Demography; Psychology; Internal medicine; Pathology","score_opus":0.03649111927102926,"score_gpt":0.2900213615037534,"score_spread":0.25353024223272413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794682159","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905584,0.00022740292,0.000050326613,0.0034282873,0.00072158175,0.00030940372,0.000058250662,0.00034173412,0.0043046],"genre_scores_gemma":[0.9942118,0.00008671331,0.0015229026,0.001273877,0.0019651586,0.000018261288,0.0000070895926,0.00004969893,0.0008644925],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9968777,0.00040680537,0.00065816264,0.0009128281,0.000451979,0.0006925803],"domain_scores_gemma":[0.9980762,0.00069867854,0.00020554048,0.0005540737,0.0000552621,0.0004102472],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00042510603,0.00040673744,0.0005358057,0.00015519414,0.000513044,0.00023582815,0.00068675494,0.0002505784,0.0012950372],"category_scores_gemma":[0.0011177537,0.0003435662,0.00016764495,0.00035482662,0.0016056942,0.00011145655,0.0003448325,0.00055541145,0.0023461536],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008156584,0.000986209,0.26424333,0.0001470155,0.00018937621,0.00012789348,0.001553656,4.9891815e-7,0.040912364,0.056246564,0.21832454,0.40911198],"study_design_scores_gemma":[0.009015724,0.0015346389,0.78145176,0.00016066154,0.00006762909,0.000039089096,0.00022970099,0.000079849604,0.018973766,0.010482561,0.17646359,0.0015010115],"about_ca_topic_score_codex":0.000031153406,"about_ca_topic_score_gemma":0.000018879258,"teacher_disagreement_score":0.51720846,"about_ca_system_score_codex":0.00001538909,"about_ca_system_score_gemma":0.00007491726,"threshold_uncertainty_score":0.99990165},"labels":[],"label_agreement":null},{"id":"W2794697420","doi":"10.1093/schbul/sby014.178","title":"43. BUILDING ON GENETICS AND PATHOPHYSIOLOGY OF SCHIZOPHRENIA TO GUIDE DISCOVERY OF NEW TREATMENTS","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Neuroscience; Medicine; Translational research; Adverse effect; Bioinformatics; Psychology; Psychiatry; Internal medicine; Biology; Pathology","score_opus":0.019185189304145745,"score_gpt":0.27325762186457714,"score_spread":0.2540724325604314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794697420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971215,0.00015596951,0.00023887321,0.00091763807,0.00026875644,0.0003181942,0.000057166464,0.0000398777,0.00088198815],"genre_scores_gemma":[0.98468673,0.00013104679,0.012938614,0.00090486865,0.00022555857,0.0000093036115,0.0000022269219,0.000037548092,0.0010641179],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981549,0.000118971446,0.00044344697,0.00063984876,0.00027973042,0.0003630963],"domain_scores_gemma":[0.9988629,0.00020878032,0.000201251,0.00050634315,0.000050378978,0.0001703239],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095489006,0.00027565466,0.00039836313,0.00021024149,0.00010397003,0.000030517578,0.00037337668,0.00010572827,0.00014136052],"category_scores_gemma":[0.00054371596,0.00024058626,0.000098071425,0.00033171911,0.00035611054,0.000046880195,0.00022482933,0.00011727957,0.00013511936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022433673,0.00015111374,0.00012957872,0.000022584883,0.000017126682,0.0000063109246,0.00021609751,0.000021245336,0.95556515,0.004461347,0.005743324,0.031422738],"study_design_scores_gemma":[0.0031785911,0.0018298415,0.0114697805,0.0001224119,0.000023434688,0.0000067677,0.000041530926,0.000025915233,0.96927685,0.00541925,0.00829604,0.00030956537],"about_ca_topic_score_codex":0.000079555946,"about_ca_topic_score_gemma":0.000013662341,"teacher_disagreement_score":0.031113172,"about_ca_system_score_codex":0.00002368546,"about_ca_system_score_gemma":0.00009948418,"threshold_uncertainty_score":0.9810823},"labels":[],"label_agreement":null},{"id":"W2794716739","doi":"10.1093/schbul/sby017.553","title":"F22. DYSLIPIDEMIA AND INFLAMMATORY MARKERS IN RELATION TO CLINICAL SYMPTOMATOLOGY IN PSYCHOTIC DISORDERS","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Internal medicine; Schizophrenia (object-oriented programming); Positive and Negative Syndrome Scale; Schizoaffective disorder; Psychosis; Dyslipidemia; Schizophreniform disorder; Medicine; Depression (economics); Major depressive disorder; Bipolar disorder; Psychiatry; Psychology; Disease","score_opus":0.016035299334926697,"score_gpt":0.289316167303295,"score_spread":0.2732808679683683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794716739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98901504,0.000038997205,0.000055587996,0.0061306055,0.00066432083,0.0004804473,0.0000024379547,0.000087984095,0.003524556],"genre_scores_gemma":[0.9965642,0.0000621767,0.00082614046,0.0022287148,0.00011623044,0.000038609964,0.0000013019703,0.000029512448,0.00013311049],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99733275,0.000557383,0.0006847721,0.00077018066,0.00018440073,0.00047048804],"domain_scores_gemma":[0.99870765,0.000659682,0.00011331029,0.00033202575,0.000014991212,0.00017235025],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007245304,0.00021581214,0.00031261382,0.00039420035,0.0000843951,0.000034910696,0.00028025036,0.00023524035,0.00030218653],"category_scores_gemma":[0.0020190433,0.00022171544,0.000055466775,0.00053233054,0.00043441157,0.00007559751,0.00011778837,0.00042597082,0.00086877774],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047302637,0.0003988433,0.9238273,0.00007260364,0.00001109961,0.00004305034,0.0010022448,0.000057015208,0.0042631677,0.014512038,0.015254687,0.03582769],"study_design_scores_gemma":[0.0034850065,0.00022853445,0.97482866,0.000095769,0.0000027747496,0.000009639844,0.000080299906,0.00036869693,0.0002288717,0.0037699703,0.016580721,0.00032104956],"about_ca_topic_score_codex":0.000026315165,"about_ca_topic_score_gemma":0.0009244599,"teacher_disagreement_score":0.051001366,"about_ca_system_score_codex":0.000030115694,"about_ca_system_score_gemma":0.000054085936,"threshold_uncertainty_score":0.99990916},"labels":[],"label_agreement":null},{"id":"W2794830735","doi":"10.1093/schbul/sby017.766","title":"F235. DIFFERENTIAL EFFECTS OF ANTIPSYCHOTICS ON NEUROINFLAMMATION AND ENERGY SENSING IN A HYPOTHALAMIC CELL LINE","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Endocrinology; Internal medicine; Inflammation; Insulin resistance; Aripiprazole; Protein kinase B; Clozapine; AMPK; MAPK/ERK pathway; Signal transduction; Medicine; Schizophrenia (object-oriented programming); Protein kinase A; Biology; Insulin; Kinase; Cell biology; Psychiatry","score_opus":0.008652773074415934,"score_gpt":0.21247407103216845,"score_spread":0.2038212979577525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794830735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997977,0.000025058645,0.0003397403,0.00038999747,0.0003842028,0.00011445079,0.0000035923915,0.00004492878,0.0007209927],"genre_scores_gemma":[0.99891865,0.00006851821,0.00041780534,0.00026833286,0.00014343762,0.0000016455942,0.0000017340918,0.000025514035,0.00015437452],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874204,0.00017184387,0.00025197543,0.0003929643,0.00019780954,0.00024337703],"domain_scores_gemma":[0.9992293,0.0003459441,0.00012154469,0.00022718411,0.000020279907,0.000055728364],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000502632,0.00017738774,0.00020018639,0.000202855,0.00007003419,0.000033260218,0.00012118903,0.00007923512,0.000032158387],"category_scores_gemma":[0.00026231265,0.00016795825,0.000042372478,0.00021818289,0.00019874748,0.000027604501,0.00005404055,0.00014295465,0.000036161986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00082961645,0.00012668231,0.00003099229,0.0000636217,0.0000013955191,0.000023058514,0.00009895392,0.000009333847,0.9847814,0.0011704448,0.0001963123,0.012668203],"study_design_scores_gemma":[0.002598022,0.00039368498,0.007052257,0.00010496661,0.0000052378837,0.000009324275,0.000007854274,0.0016978019,0.9865426,0.0007484392,0.00066690514,0.0001729013],"about_ca_topic_score_codex":0.000015285395,"about_ca_topic_score_gemma":0.000021611006,"teacher_disagreement_score":0.012495301,"about_ca_system_score_codex":0.000009190267,"about_ca_system_score_gemma":0.000015409021,"threshold_uncertainty_score":0.6849139},"labels":[],"label_agreement":null},{"id":"W2794890798","doi":"10.1093/schbul/sby017.697","title":"F166. LOW-GRADE INFLAMMATION IN FIRST-EPISODE PSYCHOSIS IS DETERMINED BY WAIST CIRCUMFERENCE INCREASE","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Waist; Overweight; Psychosis; Schizophrenia (object-oriented programming); Medicine; Antipsychotic; Population; Internal medicine; Obesity; Metabolic syndrome; Psychiatry","score_opus":0.013905999374782122,"score_gpt":0.2433566179755819,"score_spread":0.22945061860079977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794890798","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98726845,0.000066122644,0.00013115178,0.0086234035,0.00032329277,0.0004565392,0.00006433103,0.000199142,0.0028675462],"genre_scores_gemma":[0.9958443,0.00007263722,0.00050311437,0.0024968772,0.0002374456,0.0001076023,0.000014586057,0.00004588937,0.00067754585],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973619,0.00019748528,0.00051578815,0.000881992,0.00043227893,0.00061055744],"domain_scores_gemma":[0.9986577,0.00027346486,0.00018874746,0.0006207923,0.00004795818,0.0002113195],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002239214,0.00035404685,0.00029557204,0.00023753529,0.00028946775,0.0001515691,0.00067559816,0.00018144351,0.002269293],"category_scores_gemma":[0.0008480555,0.0003566675,0.0001040078,0.0006448862,0.00039197045,0.00015385094,0.0001252813,0.0003064451,0.0026066457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002859912,0.00094822276,0.01241965,0.0002264494,0.000020714697,0.0000871293,0.0017866717,0.000009803506,0.58282214,0.0020078768,0.3547304,0.04208101],"study_design_scores_gemma":[0.0064229644,0.00032663136,0.01825922,0.00028382638,0.000014381531,0.00003004463,0.00006296243,0.0011637827,0.7721287,0.0030567364,0.19709036,0.001160381],"about_ca_topic_score_codex":0.00076809793,"about_ca_topic_score_gemma":0.0011255216,"teacher_disagreement_score":0.18930656,"about_ca_system_score_codex":0.000067320136,"about_ca_system_score_gemma":0.000028718336,"threshold_uncertainty_score":0.99988854},"labels":[],"label_agreement":null},{"id":"W2795016978","doi":"10.1093/schbul/sby014.175","title":"42.2 INFLAMMATION AND GUT MICROBIOME IN FIRST-EPISODE PSYCHOSIS","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Psychosis; Weight gain; Gut flora; Inflammation; Microbiome; Schizophrenia (object-oriented programming); Medicine; Longitudinal study; Obesity; Antipsychotic; Disease; Internal medicine; Immunology; Psychiatry; Bioinformatics; Biology; Body weight; Pathology","score_opus":0.013115782993718064,"score_gpt":0.2386392557978043,"score_spread":0.22552347280408622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795016978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872091,0.00008367256,0.000040813884,0.0092497775,0.0002621268,0.00025225308,0.000010154064,0.0001043491,0.0027877667],"genre_scores_gemma":[0.9972773,0.00007146758,0.001188634,0.00073617866,0.00019840304,0.000030720657,0.0000027152555,0.000023218066,0.0004713465],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.998686,0.000088337605,0.00025829487,0.00049272337,0.00014753609,0.00032712155],"domain_scores_gemma":[0.9994329,0.00012021195,0.00007843147,0.00026586076,0.000021822068,0.00008074972],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00015756501,0.00017637134,0.00015670298,0.00021616447,0.00017321225,0.00008638567,0.00023217888,0.00010007341,0.000784415],"category_scores_gemma":[0.00030174482,0.00017202171,0.00003893537,0.00038488526,0.00029056123,0.000076899334,0.00008860735,0.00015360146,0.0013898702],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012695673,0.00020012115,0.004524109,0.00009737435,0.0000088544275,0.000026217396,0.0012810968,0.0000079679985,0.8971662,0.0053424146,0.053877972,0.036198102],"study_design_scores_gemma":[0.0055540707,0.00027759606,0.051647108,0.00018091837,0.00000776357,0.000050611372,0.00008811021,0.0002446092,0.4075644,0.003993339,0.52962166,0.0007698377],"about_ca_topic_score_codex":0.00012987932,"about_ca_topic_score_gemma":0.00086180767,"teacher_disagreement_score":0.48960182,"about_ca_system_score_codex":0.00002345471,"about_ca_system_score_gemma":0.000008190183,"threshold_uncertainty_score":0.9993877},"labels":[],"label_agreement":null},{"id":"W2795043293","doi":"10.1093/schbul/sby015.188","title":"O1.6. INCREASED COMPLEMENT FACTORS C3 AND C4 IN SCHIZOPHRENIA AND THE EARLY STAGES OF PSYCHOSIS: IMPLICATIONS FOR CLINICAL SYMPTOMATOLOGY AND CORTICAL THICKNESS","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Synaptic pruning; Psychosis; Schizophrenia (object-oriented programming); Complement system; Psychology; Neuroscience; Medicine; Immunology; Psychiatry; Immune system; Inflammation","score_opus":0.04318260919878247,"score_gpt":0.33321937101367827,"score_spread":0.2900367618148958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795043293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927701,0.0002242371,0.00014221347,0.0056135952,0.000090843474,0.0008454126,0.00007713915,0.000048583934,0.00018790428],"genre_scores_gemma":[0.9977484,0.00022798651,0.0013061892,0.0005109194,0.00004786431,0.0000980309,0.0000030189203,0.000029311655,0.000028332925],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979529,0.00046333385,0.00056704454,0.0005792038,0.000126125,0.00031141916],"domain_scores_gemma":[0.9970154,0.0022769824,0.0001872086,0.00032923507,0.000047196765,0.0001439541],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005819817,0.00020879059,0.0004380362,0.000118640026,0.00024762948,0.00005942856,0.0002447202,0.00012635246,0.000086705615],"category_scores_gemma":[0.0012171565,0.00014870868,0.00006053363,0.0001758545,0.0023971698,0.00003740013,0.0001679879,0.00022277518,0.000008908319],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008093465,0.00047819436,0.6966538,0.00012068747,0.00006564473,0.0000016533082,0.0010397914,1.506957e-7,0.0109706875,0.27022353,0.0037621073,0.008590274],"study_design_scores_gemma":[0.010992941,0.00033727236,0.9794048,0.00004577291,0.000029473258,0.000016493377,0.0001505261,0.000047320154,0.0012133194,0.005379615,0.0021814413,0.00020102387],"about_ca_topic_score_codex":0.00015489505,"about_ca_topic_score_gemma":0.00021871536,"teacher_disagreement_score":0.282751,"about_ca_system_score_codex":0.0000058223313,"about_ca_system_score_gemma":0.000034421406,"threshold_uncertainty_score":0.8832472},"labels":[],"label_agreement":null},{"id":"W2795257820","doi":"10.1093/schbul/sby018.956","title":"S169. MICROGLIAL ACTIVATION AND MORPHOLOGICAL BRAIN ALTERATIONS IN PSYCHOSIS AND PSYCHOSIS RISK","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Psychosis; Translocator protein; Neuroscience; Dorsolateral prefrontal cortex; Hippocampus; Psychology; Prefrontal cortex; Schizophrenia (object-oriented programming); Hippocampal formation; Temporal cortex; Medicine; Microglia; Internal medicine; Psychiatry; Inflammation; Cognition","score_opus":0.017113099307787642,"score_gpt":0.26345014818571605,"score_spread":0.2463370488779284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795257820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841417,0.00005383308,0.0003025955,0.014077292,0.00016731763,0.00027392115,0.00003358789,0.00007310857,0.0008766652],"genre_scores_gemma":[0.9936914,0.00013760112,0.002432773,0.0032945515,0.0001826948,0.00004445613,0.0000033804129,0.000018000359,0.0001951738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984459,0.00024183505,0.00024045896,0.0006348891,0.00015026929,0.00028664884],"domain_scores_gemma":[0.99925584,0.00031386572,0.000091860995,0.00021363157,0.000021226731,0.00010356142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021221515,0.00018575908,0.00016544298,0.00016303842,0.00028885025,0.00012937609,0.00014691477,0.00012412154,0.0004964884],"category_scores_gemma":[0.0006960762,0.00016995198,0.000035115434,0.00028017678,0.00041269083,0.00008839054,0.00007073777,0.0002605831,0.000161944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021996775,0.00040485937,0.0067986106,0.00001846019,0.000011017835,0.000017186412,0.001202074,0.0000028142035,0.88511825,0.003203129,0.04929553,0.051728375],"study_design_scores_gemma":[0.013753666,0.0015489148,0.336687,0.0001803848,0.000027239737,0.0001906627,0.00031316243,0.0007047856,0.48319167,0.017007884,0.14487815,0.0015164813],"about_ca_topic_score_codex":0.0001655477,"about_ca_topic_score_gemma":0.00015637127,"teacher_disagreement_score":0.4019266,"about_ca_system_score_codex":0.000015137387,"about_ca_system_score_gemma":0.000010144346,"threshold_uncertainty_score":0.69304407},"labels":[],"label_agreement":null},{"id":"W2795295421","doi":"10.1093/schbul/sby017.577","title":"F46. LUMATEPERONE (ITI-007): FAVORABLE SAFETY PROFILE IN AN OPEN LABEL SAFETY SWITCHING STUDY FROM STANDARD-OF-CARE ANTIPSYCHOTIC THERAPY IN PATIENTS WITH SCHIZOPHRENIA","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Atypical antipsychotic; Psychology; Schizophrenia (object-oriented programming); Antipsychotic; Risperidone; Medicine; Pharmacology; Psychiatry","score_opus":0.023306488492664975,"score_gpt":0.2808597664464885,"score_spread":0.25755327795382355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795295421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942613,0.00011688434,0.00003949595,0.00023866387,0.0003048483,0.0036399488,0.00041754084,0.00012332613,0.00085794163],"genre_scores_gemma":[0.9948979,0.000042481493,0.0043307673,0.00029781027,0.00008151813,0.00009775306,0.000083666244,0.00012260464,0.000045514113],"study_design_codex":"randomized_trial","study_design_gemma":"observational","domain_scores_codex":[0.9948204,0.00086063816,0.0010230298,0.0015522175,0.00090746355,0.0008362357],"domain_scores_gemma":[0.9978026,0.00021817171,0.00039381214,0.001174593,0.00020406004,0.00020676754],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006212986,0.0006049092,0.00096380163,0.0003879498,0.00041749416,0.0002921815,0.001728019,0.00018101519,0.0013305488],"category_scores_gemma":[0.00019693286,0.0005141697,0.000050262017,0.0011607677,0.00029068993,0.00053026044,0.00040496528,0.00064605806,0.00017438563],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.42231348,0.014537889,0.39514,0.00012284196,0.0001073011,0.00010797597,0.0168996,0.000098892786,0.03080739,0.0009475053,0.0005340172,0.118383095],"study_design_scores_gemma":[0.102231555,0.013820801,0.8629939,0.00065863243,0.000019164512,0.0000015317977,0.0031650397,0.00009905714,0.014170977,0.0005874456,0.0009687646,0.0012831143],"about_ca_topic_score_codex":0.0009823344,"about_ca_topic_score_gemma":0.0039406973,"teacher_disagreement_score":0.4678539,"about_ca_system_score_codex":0.00016957788,"about_ca_system_score_gemma":0.00027688878,"threshold_uncertainty_score":0.999731},"labels":[],"label_agreement":null},{"id":"W2795512339","doi":"10.1016/j.physbeh.2018.03.036","title":"The 5α-reductase inhibitor finasteride increases suicide-related aggressive behaviors and blocks clozapine-induced beneficial effects in an animal model of schizophrenia","year":2018,"lang":"en","type":"article","venue":"Physiology & Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Université de Sherbrooke","keywords":"Clozapine; Allopregnanolone; Psychology; Neuroactive steroid; Impulsivity; Schizophrenia (object-oriented programming); Prepulse inhibition; Context (archaeology); Atypical antipsychotic; Pharmacology; Psychiatry; Antipsychotic; Medicine; Internal medicine; GABAA receptor; Receptor","score_opus":0.023669649700887856,"score_gpt":0.29212518927179176,"score_spread":0.2684555395709039,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795512339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988121,0.00013721685,5.137462e-7,0.00004600586,0.0002386128,0.00063013536,0.00006702995,0.000060657956,0.000007755147],"genre_scores_gemma":[0.99949336,0.000030957824,0.00006013529,0.0000983566,0.00011380543,0.00014221245,0.000012908261,0.000036442147,0.000011814669],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99784285,0.0003001244,0.00045723087,0.0006916235,0.00019241056,0.0005157737],"domain_scores_gemma":[0.99874496,0.0002691637,0.00033811943,0.00043402353,0.00007364721,0.00014005486],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011792989,0.00032080614,0.00040131997,0.000162243,0.00033140244,0.00003314706,0.00040195498,0.00021329118,0.000019523024],"category_scores_gemma":[0.00034786423,0.00025287337,0.00008648281,0.00030529383,0.0010515179,0.0002167461,0.00022861539,0.00032257312,0.0000082929255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010624123,0.00060506235,0.0022277564,0.000008202732,0.0000028372112,0.00003125281,0.00031329613,0.0000125008,0.98947877,0.00021297051,0.000014234957,0.0060307197],"study_design_scores_gemma":[0.0018288582,0.001356382,0.23150143,0.00005893253,0.000049614406,0.000021802809,0.00008235578,0.000988096,0.7634882,0.00035830174,0.0000011443075,0.00026490018],"about_ca_topic_score_codex":0.00022600229,"about_ca_topic_score_gemma":0.00027511865,"teacher_disagreement_score":0.22927368,"about_ca_system_score_codex":0.000026224021,"about_ca_system_score_gemma":0.00010718072,"threshold_uncertainty_score":0.9999924},"labels":[],"label_agreement":null},{"id":"W2796284997","doi":"10.1007/s12035-018-1016-x","title":"The Compensatory Immune-Regulatory Reflex System (CIRS) in Depression and Bipolar Disorder","year":2018,"lang":"en","type":"review","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":324,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Major depressive disorder; Bipolar disorder; Immune system; Hypoactivity; Mood disorders; Hemopexin; Psychology; Mood; Antidepressant; Immunology; Internal medicine; Medicine; Neuroscience; Psychiatry; Anxiety; Biology","score_opus":0.022201287027062373,"score_gpt":0.28683926873015125,"score_spread":0.2646379817030889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796284997","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006813627,0.99084175,0.000014843825,0.000023511884,0.00078579114,0.0009683262,0.000022099348,0.000117210526,0.000412833],"genre_scores_gemma":[0.0090234345,0.9902967,0.000009197592,0.00027158845,0.000052413117,0.00011657255,0.000016712029,0.00011052233,0.000102845996],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9951073,0.0021850588,0.0007576028,0.0011535435,0.00016239005,0.0006341234],"domain_scores_gemma":[0.9977762,0.00066050707,0.00040007717,0.0010472233,0.000021476997,0.000094514435],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037841965,0.0005704525,0.0011374081,0.00024919224,0.00034213145,0.00007024037,0.0009241517,0.0005057174,0.000007362402],"category_scores_gemma":[0.00028832196,0.00037833524,0.00031461575,0.00040471615,0.0008998391,0.000048058297,0.0005807966,0.0006801694,0.00011373357],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006245589,0.00014445603,0.00005437266,0.007265424,0.00006261783,0.00044018787,0.00007288253,0.0000032341825,0.02063492,0.007330575,0.00056485576,0.963364],"study_design_scores_gemma":[0.00031508505,0.00008039415,0.00012481713,0.0013492474,0.000043565622,0.00024377064,0.0000138606365,0.000012029499,0.000692327,0.00003343301,0.99670553,0.00038590995],"about_ca_topic_score_codex":0.00001554204,"about_ca_topic_score_gemma":0.000018042383,"teacher_disagreement_score":0.9961407,"about_ca_system_score_codex":0.000064557215,"about_ca_system_score_gemma":0.00011432305,"threshold_uncertainty_score":0.99986684},"labels":[],"label_agreement":null},{"id":"W2796846300","doi":"10.1186/s12882-018-0841-5","title":"Increased urinary excretion of kynurenic acid is associated with non-recovery from acute kidney injury in critically ill patients","year":2018,"lang":"en","type":"article","venue":"BMC Nephrology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Kynurenic acid; Medicine; Kynurenine; Acute kidney injury; Internal medicine; Kynurenine pathway; Creatinine; Urinary system; Excretion; Nephrology; Urology; Endocrinology; Tryptophan; Chemistry; Biochemistry; Glutamate receptor","score_opus":0.011187567366589025,"score_gpt":0.24541136265335556,"score_spread":0.23422379528676654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796846300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99756485,0.0000049905802,0.000333422,0.00032638529,0.00019017297,0.00029476368,0.0004622425,0.000046394616,0.0007768001],"genre_scores_gemma":[0.9719173,0.00001014174,0.00048347068,0.027358796,0.00005073058,0.000025256277,0.00008861996,0.000024555624,0.000041177766],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981964,0.00032258057,0.00032949654,0.00051068125,0.00023687429,0.00040392106],"domain_scores_gemma":[0.9988938,0.00025782027,0.00015578048,0.0003151968,0.00024446883,0.00013295867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001095047,0.0001956936,0.00033110238,0.00019723659,0.000063145424,0.0000135260625,0.00029988287,0.0002308091,0.00045812206],"category_scores_gemma":[0.002310292,0.00017908655,0.00006950893,0.0004259137,0.00052639766,0.00019242,0.000110393274,0.00018148686,0.00008099668],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006309221,0.001853082,0.119766265,0.000022795639,0.000082821585,0.000044994427,0.00057756633,7.294837e-7,0.85737926,0.0001140619,0.012700689,0.001148524],"study_design_scores_gemma":[0.005207605,0.0044022053,0.7796341,0.00006167073,0.00005575388,0.0000055548767,0.000023469385,0.0003126228,0.2069629,0.0020040327,0.0009710178,0.00035903382],"about_ca_topic_score_codex":0.00013705646,"about_ca_topic_score_gemma":0.00007564868,"teacher_disagreement_score":0.6598679,"about_ca_system_score_codex":0.000048808837,"about_ca_system_score_gemma":0.00017256316,"threshold_uncertainty_score":0.73029375},"labels":[],"label_agreement":null},{"id":"W2796889128","doi":"10.1016/j.biopsych.2018.02.1054","title":"S162. Antidepressant and Pro-Cognitive Effects of a Novel Series of GABA-A Receptor Positive Allosteric Modulators With α5 Subunit Efficacy Properties","year":2018,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"GABAA receptor; Mood; Allosteric regulation; Cognition; Neuroscience; Mood disorders; Antidepressant; Receptor; Psychology; Medicine; Pharmacology; Psychiatry; Internal medicine; Hippocampus","score_opus":0.036124096232798976,"score_gpt":0.2522672747354765,"score_spread":0.21614317850267753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796889128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99790967,0.00030324867,0.00009514041,0.0001605765,0.00022271977,0.00076466287,0.00006099087,0.00005247119,0.0004305463],"genre_scores_gemma":[0.9986418,0.000053622713,0.00086340576,0.0002920655,0.000068633344,0.000021999364,0.0000034149248,0.00001569043,0.000039375882],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868715,0.00014281947,0.00025490616,0.00048605326,0.00016638543,0.00026268366],"domain_scores_gemma":[0.9992696,0.00019942982,0.00019813329,0.0001603923,0.00009515142,0.00007726728],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000699433,0.00022784591,0.00033876023,0.00007159379,0.000103812876,0.0000172738,0.00017644765,0.00011895101,0.000018343153],"category_scores_gemma":[0.00042669286,0.0001321961,0.000062720625,0.0002998671,0.0016884896,0.00012922418,0.00010840698,0.00011744111,0.0000054323827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027724665,0.0011072654,0.025349723,0.00021032146,0.00004407812,0.0000021177639,0.00073505344,6.851989e-7,0.9672958,0.0014278488,0.000048224607,0.0010063739],"study_design_scores_gemma":[0.0022030817,0.005299273,0.3077814,0.00049749296,0.00002134179,0.000023826093,0.00038511027,0.000020022211,0.6832828,0.00017279127,0.00003791816,0.00027494534],"about_ca_topic_score_codex":0.000008763728,"about_ca_topic_score_gemma":0.000005599812,"teacher_disagreement_score":0.28401303,"about_ca_system_score_codex":0.000005160576,"about_ca_system_score_gemma":0.000044727716,"threshold_uncertainty_score":0.62213105},"labels":[],"label_agreement":null},{"id":"W2797260314","doi":"10.1016/j.biopsych.2018.02.136","title":"118. Single-Cell Transcriptome of the Depressed and Suicidal Brain","year":2018,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Transcriptome; Neuroscience; Cell; Gene expression; Biology; Gene; Psychology; Genetics","score_opus":0.04280463424147404,"score_gpt":0.25590473301762323,"score_spread":0.2131000987761492,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797260314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98790884,0.00023322564,0.00009243866,0.003421573,0.00071178435,0.00016606042,0.000015968719,0.00004974045,0.0074003744],"genre_scores_gemma":[0.994381,0.000008366705,0.0002312621,0.0050796047,0.00012516534,0.000003173719,4.419237e-7,0.000006870737,0.00016408738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904317,0.00014104598,0.00017113356,0.00032040974,0.000109696055,0.00021456458],"domain_scores_gemma":[0.9995074,0.00014231363,0.000065487366,0.00021729672,0.000012019329,0.000055470195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008253695,0.00011547029,0.00012731178,0.000023929604,0.00011743583,0.000015500073,0.0003271956,0.00011309752,0.000117974734],"category_scores_gemma":[0.00018100886,0.0000637532,0.00008382334,0.00020034314,0.0007883455,0.000034430403,0.00005858664,0.000110648405,0.000015745894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006646874,0.00022088396,0.017469276,0.000011493208,0.0000015119567,2.6609985e-7,0.00006842294,1.7333451e-7,0.9765327,0.0028600993,0.0022214227,0.00054729235],"study_design_scores_gemma":[0.0021335643,0.0013775715,0.34858972,0.000026961794,0.000008955836,0.000017632454,0.00022497354,0.00004444569,0.6172656,0.017238483,0.012676922,0.00039517786],"about_ca_topic_score_codex":0.00000708016,"about_ca_topic_score_gemma":0.000017182621,"teacher_disagreement_score":0.3592671,"about_ca_system_score_codex":0.000003649585,"about_ca_system_score_gemma":0.000019191699,"threshold_uncertainty_score":0.2904692},"labels":[],"label_agreement":null},{"id":"W2797924446","doi":"10.1038/s41386-018-0061-5","title":"Interaction between TSPO—a neuroimmune marker—and redox status in clinical high risk for psychosis: a PET–MRS study","year":2018,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institutes of Health; Lundbeck Canada; National Institute of Mental Health; H. Lundbeck A/S","keywords":"Translocator protein; Psychosis; Oxidative stress; Glutathione; Schizophrenia (object-oriented programming); Psychology; Prefrontal cortex; Internal medicine; Antipsychotic; Neuroscience; Binding potential; Dorsolateral prefrontal cortex; Endocrinology; Medicine; Positron emission tomography; Chemistry; Psychiatry; Inflammation; Neuroinflammation; Biochemistry; Cognition","score_opus":0.044789411504906264,"score_gpt":0.3950501639407262,"score_spread":0.3502607524358199,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797924446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910595,0.00002972879,0.000046064244,0.0008002723,0.0055374047,0.001751071,0.00005570165,0.00014854339,0.0005717091],"genre_scores_gemma":[0.9950747,0.0005280563,0.00011123117,0.00316559,0.0006773851,0.00021258344,0.0000034396455,0.000071614115,0.0001554382],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99489576,0.0018533362,0.0009460833,0.0013388465,0.00021650059,0.00074950396],"domain_scores_gemma":[0.9967456,0.002138739,0.00037837037,0.00043965815,0.00006585897,0.00023176825],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007162386,0.00033659447,0.00050722994,0.00035325726,0.00025665484,0.00006665879,0.00044905132,0.00010980172,0.00022399904],"category_scores_gemma":[0.0011685948,0.00033536198,0.00012995681,0.000597939,0.00047157795,0.0002278082,0.00015107641,0.00082686724,0.00010822],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0143256,0.0047605503,0.65235555,0.000057639943,0.0001236099,0.00026042617,0.0013604285,0.000012111519,0.14962238,0.0001129901,0.016246645,0.16076209],"study_design_scores_gemma":[0.012062659,0.0044273622,0.95821494,0.000011011355,0.0000730875,0.000025578154,0.00020129334,0.00034329423,0.0013083101,0.00042653215,0.022584531,0.00032138656],"about_ca_topic_score_codex":0.000109749555,"about_ca_topic_score_gemma":0.00009549887,"teacher_disagreement_score":0.30585942,"about_ca_system_score_codex":0.00003183048,"about_ca_system_score_gemma":0.00003845759,"threshold_uncertainty_score":0.9999098},"labels":[],"label_agreement":null},{"id":"W2797957016","doi":"10.1016/j.biopsych.2018.02.671","title":"F58. Low-Dose Penicillin Exposure in Adolescent Mice Leads to Long-Term Deficits in Social Odour Recognition: Implications for Microbiota &amp; Olfaction in Disorders Involving Social Communication","year":2018,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Penicillin; Neurochemistry; Microbiome; Olfaction; Offspring; Psychology; Schizophrenia (object-oriented programming); Medicine; Neuroscience; Physiology; Developmental psychology; Psychiatry; Pregnancy; Antibiotics; Bioinformatics; Biology; Neurology","score_opus":0.15512073149171038,"score_gpt":0.33834437464645445,"score_spread":0.18322364315474407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797957016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98959905,0.0002331704,0.00013997726,0.008314179,0.00032879846,0.0010965406,0.000071086586,0.00006372368,0.00015347682],"genre_scores_gemma":[0.996224,0.00021769015,0.00059369614,0.0024185465,0.00020681649,0.00019205034,0.0001131442,0.000019673107,0.000014396373],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979819,0.00034563814,0.0005171679,0.0006155985,0.000084087886,0.00045558476],"domain_scores_gemma":[0.9993654,0.00016143554,0.00015297353,0.0002168311,0.000045865218,0.000057502766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002977871,0.00022024078,0.00024708104,0.00024105763,0.00038029155,0.000050362894,0.00044288902,0.00033144347,0.000036669313],"category_scores_gemma":[0.0002795259,0.00021527095,0.000114462935,0.00078134064,0.00022153722,0.00012640294,0.00011184696,0.00035167453,0.00007310224],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086154445,0.0020103226,0.68887866,0.00006743219,0.0000031267434,2.6910675e-7,0.0009535446,0.000004536933,0.287299,0.0011874593,0.0016518446,0.017082268],"study_design_scores_gemma":[0.0018164675,0.00014338142,0.992234,0.000086374144,0.000002070665,0.0000016514505,0.00018892613,0.0000044667263,0.0008252811,0.004194411,0.00020414723,0.0002988217],"about_ca_topic_score_codex":0.000042321848,"about_ca_topic_score_gemma":0.008665835,"teacher_disagreement_score":0.30335537,"about_ca_system_score_codex":0.00015150539,"about_ca_system_score_gemma":0.00006999946,"threshold_uncertainty_score":0.87784946},"labels":[],"label_agreement":null},{"id":"W2797997643","doi":"10.1016/j.biopsych.2018.02.432","title":"T96. Cortical Astroglial-Mediated Plasticity in Chronic Stress","year":2018,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Neuroscience; Neuroplasticity; Plasticity; Glutamate receptor; Synaptic plasticity; Chronic stress; Psychology; Biology; Receptor","score_opus":0.037277427945590726,"score_gpt":0.28742472918127654,"score_spread":0.2501473012356858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797997643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99492663,0.000063641055,0.00021081419,0.0005191052,0.0010142203,0.00019049503,0.000050854447,0.00015738525,0.0028668384],"genre_scores_gemma":[0.9976844,0.000025475258,0.0002366169,0.0013519735,0.0006355137,0.000013362489,0.0000061922697,0.00000979863,0.000036645313],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99827766,0.00019105186,0.0002848865,0.000558049,0.00016206595,0.0005262642],"domain_scores_gemma":[0.9992932,0.00031947173,0.00006078034,0.00016753342,0.000015093002,0.00014388481],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007344139,0.00018034437,0.00019857594,0.000067116816,0.000118501936,0.0000266987,0.00035015124,0.00021096172,0.0008125486],"category_scores_gemma":[0.000963951,0.00012952858,0.00007094311,0.0003629893,0.0006906795,0.000054715932,0.00009825736,0.0003399557,0.0007653193],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088789256,0.0016987658,0.31568187,0.00004194776,0.000011378227,0.000039115814,0.00010035794,0.000022366528,0.6414686,0.03187148,0.005345863,0.0028303964],"study_design_scores_gemma":[0.002726711,0.0024322525,0.95255345,0.00006662457,0.0000044117287,0.000011427192,0.000121914374,0.0012790447,0.031207802,0.0044230963,0.004602253,0.0005710178],"about_ca_topic_score_codex":0.000011472702,"about_ca_topic_score_gemma":0.00017341884,"teacher_disagreement_score":0.6368716,"about_ca_system_score_codex":0.000058923233,"about_ca_system_score_gemma":0.00011675184,"threshold_uncertainty_score":0.98368865},"labels":[],"label_agreement":null},{"id":"W2799466538","doi":"10.1007/s00406-018-0897-z","title":"Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders","year":2018,"lang":"en","type":"article","venue":"European Archives of Psychiatry and Clinical Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Norges Forskningsråd; European Commission; Seventh Framework Programme; Stiftelsen Kristian Gerhard Jebsen","keywords":"Internal medicine; Osteoprotegerin; Positive and Negative Syndrome Scale; Dyslipidemia; Schizophrenia (object-oriented programming); Psychosis; Schizophreniform disorder; Depression (economics); Medicine; Schizoaffective disorder; Bipolar disorder; Major depressive disorder; Triglyceride; Endocrinology; Psychology; Psychiatry; Cholesterol; Receptor; Disease; Lithium (medication)","score_opus":0.0294346852013786,"score_gpt":0.3125059061516573,"score_spread":0.2830712209502787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2799466538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98847425,0.000042055715,0.00037288322,0.0022626966,0.0009693583,0.00025802403,0.000028834787,0.000051505307,0.00754039],"genre_scores_gemma":[0.99764204,0.00040283808,0.00034926354,0.0012325175,0.00018264374,0.0000022615943,4.2064602e-7,0.000020994621,0.00016700404],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9966619,0.0011311012,0.0006705398,0.0008973223,0.00022050111,0.00041865703],"domain_scores_gemma":[0.99802613,0.001117029,0.00035891385,0.0003007407,0.0000098324845,0.00018736794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049859594,0.00019953326,0.00032366798,0.00015396517,0.00020601196,0.000051285246,0.0005010633,0.000059364032,0.000011340067],"category_scores_gemma":[0.0014883388,0.00018411348,0.00008428621,0.00035742708,0.0016479733,0.00019391332,0.00027109555,0.00037468813,0.0000138128025],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050780378,0.00019940303,0.9760969,0.00003435433,0.0000037554457,0.000002141376,0.00021729952,0.0000014516721,0.0050485805,0.0011144734,0.000044131666,0.01718672],"study_design_scores_gemma":[0.0011538933,0.00067863794,0.992463,0.00006903294,0.000010230705,0.0000077469085,0.000043751224,0.00027845113,0.0006592347,0.0038395054,0.0006030563,0.00019346894],"about_ca_topic_score_codex":0.0000053837484,"about_ca_topic_score_gemma":0.00009697893,"teacher_disagreement_score":0.016993253,"about_ca_system_score_codex":0.0000026883379,"about_ca_system_score_gemma":0.000041327043,"threshold_uncertainty_score":0.750793},"labels":[],"label_agreement":null},{"id":"W2800380700","doi":"10.1093/schbul/sby038","title":"The Emerging Immunogenetic Architecture of Schizophrenia","year":2018,"lang":"en","type":"review","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Genome-wide association study; Schizophrenia (object-oriented programming); Disease; Pleiotropy; Genetic architecture; Immune dysregulation; Genetic association; Biology; Immunology; Neuroscience; Gene; Medicine; Genetics; Phenotype; Single-nucleotide polymorphism; Psychiatry","score_opus":0.028233664790458482,"score_gpt":0.2880019376529996,"score_spread":0.2597682728625411,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800380700","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014752966,0.99486893,0.000030564737,0.00041275524,0.0011285415,0.0010925363,0.00010360631,0.00016880003,0.0020467518],"genre_scores_gemma":[0.00013163051,0.99653745,0.00081981183,0.00011090545,0.0006469357,0.00014914134,0.000017691209,0.00018703322,0.0013994096],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99480873,0.00096880394,0.0013388532,0.001195392,0.0007565944,0.0009316386],"domain_scores_gemma":[0.99552476,0.0014366214,0.0010415018,0.0017467272,0.00007413889,0.00017624476],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00055274426,0.0009413737,0.0016321742,0.0003455049,0.0007697116,0.00019176524,0.0026350417,0.0004423396,0.00067316025],"category_scores_gemma":[0.0013979814,0.000603037,0.001178281,0.0010260955,0.0011836519,0.00002685935,0.00062048715,0.0011339858,0.0019512267],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023439646,0.00005089527,6.3863915e-8,0.002191438,0.00006678274,0.000012830937,0.000050658233,0.0000013556833,0.00017677521,0.0015552226,0.007553644,0.98810595],"study_design_scores_gemma":[0.0006603978,0.000109707275,0.0000017282235,0.0037828553,0.00015584491,0.00009991934,0.000013893507,0.0000014846204,0.00065047946,0.00096714625,0.99293554,0.00062098156],"about_ca_topic_score_codex":0.000012600107,"about_ca_topic_score_gemma":0.000014057477,"teacher_disagreement_score":0.98748493,"about_ca_system_score_codex":0.000053218275,"about_ca_system_score_gemma":0.00042560097,"threshold_uncertainty_score":0.9996421},"labels":[],"label_agreement":null},{"id":"W2800409885","doi":"10.1016/j.ajp.2018.04.031","title":"A case of spontaneous resolution of myocarditis in a schizophrenic patient treated with clozapine without treatment discontinuation","year":2018,"lang":"en","type":"letter","venue":"Asian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Schizophrenia (object-oriented programming); Clozapine; Inflammation; Procalcitonin; Medicine; Context (archaeology); Antipsychotic; Discontinuation; Internal medicine; Confounding; Pathophysiology; C-reactive protein; Gastroenterology; Psychiatry","score_opus":0.0136404941120653,"score_gpt":0.239691643116323,"score_spread":0.22605114900425768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800409885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96763825,0.0004406146,0.000069198344,0.02998779,0.0006602877,0.00049660535,0.00012982506,0.0000118209955,0.00056558044],"genre_scores_gemma":[0.99322927,0.00010435026,0.0016733035,0.003977753,0.00085157785,0.000009370426,0.00001822221,0.000057340847,0.00007881184],"study_design_codex":"not_applicable","study_design_gemma":"case_report","domain_scores_codex":[0.997431,0.00039130633,0.001055857,0.00035037324,0.000470011,0.00030145972],"domain_scores_gemma":[0.99748194,0.000059420054,0.0018818624,0.00037517285,0.00012851614,0.000073089286],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012595569,0.00035507735,0.00077597826,0.0006487432,0.00005055437,0.000020504187,0.00022123374,0.0002801536,0.000045046447],"category_scores_gemma":[0.00007458874,0.0002573174,0.0003069311,0.0004532781,0.00025995955,0.00014560013,0.000017825449,0.0005613202,0.0000030418169],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.04400365,0.011345613,0.029284297,0.0016773475,0.0026693803,0.31034613,0.017202986,0.00059753994,0.013916957,0.0007597102,0.32586047,0.24233593],"study_design_scores_gemma":[0.07253479,0.13187681,0.026454635,0.017171191,0.0027671435,0.6661766,0.007397887,0.000573758,0.026018213,0.0034290608,0.04119049,0.004409394],"about_ca_topic_score_codex":0.00009787141,"about_ca_topic_score_gemma":0.00073867256,"teacher_disagreement_score":0.35583052,"about_ca_system_score_codex":0.00014614052,"about_ca_system_score_gemma":0.00041588608,"threshold_uncertainty_score":0.9999879},"labels":[],"label_agreement":null},{"id":"W2800413934","doi":"10.1080/15622975.2018.1468031","title":"Reduced peripheral availability of tryptophan and increased activation of the kynurenine pathway and cortisol correlate with major depression and suicide","year":2018,"lang":"en","type":"article","venue":"The World Journal of Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Alliance for Research on Schizophrenia and Depression; Brain Research Foundation; Brain and Behavior Research Foundation","keywords":"Major depressive disorder; Kynurenine; Kynurenine pathway; Suicidal ideation; Depression (economics); Internal medicine; Psychopathology; Biomarker; Psychology; Endocrinology; Poison control; Psychiatry; Medicine; Tryptophan; Suicide prevention; Chemistry; Biochemistry","score_opus":0.019244626596281386,"score_gpt":0.25558959363995687,"score_spread":0.23634496704367547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800413934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99787176,0.00044870752,0.00003121463,0.0011166666,0.00015276483,0.00017269515,0.000005327177,0.000005435935,0.0001954152],"genre_scores_gemma":[0.9991759,0.000067345245,0.0003028229,0.00033925613,0.00006907472,0.0000010851953,2.0461997e-7,0.000005238451,0.00003906746],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998908,0.00029494578,0.0003464943,0.00017382174,0.00015476512,0.000121992496],"domain_scores_gemma":[0.9989439,0.0002549577,0.0005229506,0.00015957594,0.000054934662,0.00006364042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028556134,0.00011700673,0.00022890577,0.00004401384,0.00014947398,0.000013535043,0.0001779133,0.00005607484,0.00004493814],"category_scores_gemma":[0.00024777005,0.00004848105,0.000046301502,0.00021914794,0.0011689393,0.00007564507,0.000072844035,0.00023090873,1.40293e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021758005,0.000120103774,0.17265917,0.00001746091,0.000012803679,4.890647e-7,0.00016201193,0.0000012861041,0.82062805,0.000325354,0.00007702884,0.0038204533],"study_design_scores_gemma":[0.0013858402,0.00094074337,0.84484994,0.00014763686,0.00001573481,0.000075147545,0.00012896587,0.000035232264,0.14986967,0.0024402987,0.00003627328,0.00007451732],"about_ca_topic_score_codex":0.000014262708,"about_ca_topic_score_gemma":0.00004335815,"teacher_disagreement_score":0.6721908,"about_ca_system_score_codex":0.0000066251105,"about_ca_system_score_gemma":0.000042858686,"threshold_uncertainty_score":0.43070054},"labels":[],"label_agreement":null},{"id":"W2801080264","doi":"10.1016/j.schres.2018.04.032","title":"Decreased peripheral TNF alpha (TNF-α) mRNA expression in patients with treatment-resistant schizophrenia","year":2018,"lang":"en","type":"letter","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"National Health and Medical Research Council; Australian Government; Brain Research Foundation; Brain and Behavior Research Foundation","keywords":"Mood disorders; Bipolar disorder; Mood; Schizophrenia (object-oriented programming); PsycINFO; Medicine; Psychiatry; Adverse effect; Bioinformatics; Psychopharmacology; Oncology; Internal medicine; Pharmacology; Clinical psychology; Anxiety; MEDLINE; Biology","score_opus":0.040603898464249416,"score_gpt":0.3031394165222456,"score_spread":0.26253551805799613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801080264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9547061,0.00029873243,0.000008624653,0.036983386,0.00062828354,0.0033948412,0.0005615831,0.00033227482,0.0030862011],"genre_scores_gemma":[0.88808787,0.0003722713,0.004056613,0.0774465,0.008226053,0.0020502002,0.0018163266,0.0013289716,0.0166152],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9873365,0.0023029484,0.0008590818,0.0028507349,0.0038733517,0.0027773576],"domain_scores_gemma":[0.99561065,0.0010300777,0.00031019168,0.0021265743,0.00040794432,0.0005145513],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006378577,0.0012299317,0.0010937754,0.0017694338,0.0009360652,0.0006825849,0.0021147963,0.0012416813,0.0016408322],"category_scores_gemma":[0.00094725745,0.00091639225,0.00031905228,0.0021284951,0.001538097,0.00052827137,0.0005198939,0.0039565186,0.00083277305],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.05558769,0.0023825585,0.0020907088,0.00038813316,0.00011188519,0.002574332,0.0006028556,0.0000062053327,0.02743039,0.00013170824,0.8881267,0.020566856],"study_design_scores_gemma":[0.0853377,0.012405549,0.05546099,0.0030636282,0.00008879639,0.000036547626,0.00018031572,0.00019260525,0.102079116,0.0035145297,0.7322755,0.0053647626],"about_ca_topic_score_codex":0.0003286198,"about_ca_topic_score_gemma":0.0004958232,"teacher_disagreement_score":0.15585122,"about_ca_system_score_codex":0.0010269325,"about_ca_system_score_gemma":0.0013496762,"threshold_uncertainty_score":0.9999452},"labels":[],"label_agreement":null},{"id":"W2801521285","doi":"10.4103/psychiatry.indianjpsychiatry_185_17","title":"Serum cholesterol and Suicide in first episode psychosis","year":2017,"lang":"en","type":"article","venue":"Indian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Psychopathology; Psychosis; Psychiatry; Suicide attempt; Psychology; Cohort; Schizophrenia (object-oriented programming); Depression (economics); Internal medicine; Impulsivity; Poison control; Clinical psychology; Medicine; Suicide prevention; Medical emergency","score_opus":0.020670229213641096,"score_gpt":0.28356614316427986,"score_spread":0.26289591395063877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801521285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9805906,0.00027438955,0.000012386515,0.016405344,0.0014851422,0.00008156436,0.000007732292,0.0000068780864,0.0011359913],"genre_scores_gemma":[0.9976485,0.00018571914,0.00039697913,0.0014728897,0.00021950883,0.0000015820558,6.589873e-8,0.00001662403,0.000058163238],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989069,0.0000546895,0.0003656445,0.00020055295,0.00020498307,0.00026724493],"domain_scores_gemma":[0.99895555,0.000053936834,0.00047828205,0.0003265219,0.0000167476,0.0001689783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023415912,0.00013335924,0.00020350635,0.00022945312,0.00028043313,0.00020281938,0.00060990587,0.000081949416,0.00005393541],"category_scores_gemma":[0.00022430132,0.00011807769,0.00008658799,0.00008616404,0.00017311526,0.0004809038,0.000045187855,0.00036084227,0.000019900996],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058104124,0.00012181033,0.9886808,0.00003425173,0.0000065203462,0.0000841494,0.00041047056,0.00000615431,0.0005669352,0.00037179166,0.0014002938,0.008258722],"study_design_scores_gemma":[0.002057844,0.0001594068,0.98652446,0.0002821205,0.0000051089905,0.0004265147,0.00018638726,0.0000071385066,0.0021426324,0.006571133,0.0014773319,0.00015988963],"about_ca_topic_score_codex":0.000051254152,"about_ca_topic_score_gemma":0.0031451967,"teacher_disagreement_score":0.017057898,"about_ca_system_score_codex":0.000015876354,"about_ca_system_score_gemma":0.000038354683,"threshold_uncertainty_score":0.48150682},"labels":[],"label_agreement":null},{"id":"W2801598945","doi":"10.1007/s12640-018-9906-2","title":"Generalized Anxiety Disorder (GAD) and Comorbid Major Depression with GAD Are Characterized by Enhanced Nitro-oxidative Stress, Increased Lipid Peroxidation, and Lowered Lipid-Associated Antioxidant Defenses","year":2018,"lang":"en","type":"article","venue":"Neurotoxicity Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Oxidative stress; Lipid peroxidation; Chemistry; Malondialdehyde; Paraoxonase; Internal medicine; Superoxide dismutase; Endocrinology; Biochemistry; Medicine","score_opus":0.02816578078371036,"score_gpt":0.2980357926703537,"score_spread":0.26987001188664334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801598945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99601996,0.000098986435,0.00017018971,0.00042194343,0.0000728956,0.0023486412,0.00041468238,0.00019255502,0.00026012163],"genre_scores_gemma":[0.9973005,0.00086274935,0.000099955396,0.00074722787,0.00014969992,0.00034852477,0.000058628226,0.000083633764,0.00034909043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99399394,0.0019214954,0.00043801602,0.0014271446,0.001192974,0.0010264191],"domain_scores_gemma":[0.99745905,0.0007378493,0.00030376753,0.00057490444,0.00048635056,0.000438101],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006137043,0.00047466595,0.00056061486,0.00028678463,0.0012200566,0.00043950463,0.00048431222,0.00029151313,0.00026848432],"category_scores_gemma":[0.0020633417,0.00039029605,0.00006808767,0.0010470928,0.0016274025,0.0005672976,0.0004336752,0.00093730754,0.000025264073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017218911,0.00060893013,0.04453122,0.00007511141,0.000021808873,0.000014407055,0.00029866747,3.5886478e-7,0.9510427,0.000020839003,0.00067927415,0.0009847883],"study_design_scores_gemma":[0.005187561,0.0006937052,0.13260004,0.00015712561,0.000012647126,0.000017755185,0.00020866317,0.00027619774,0.8591167,0.000054535703,0.0012483621,0.00042673337],"about_ca_topic_score_codex":0.00038692215,"about_ca_topic_score_gemma":0.0005326972,"teacher_disagreement_score":0.09192602,"about_ca_system_score_codex":0.000057656314,"about_ca_system_score_gemma":0.000121102115,"threshold_uncertainty_score":0.9998549},"labels":[],"label_agreement":null},{"id":"W2802046728","doi":"10.1177/0706743718773728","title":"An Overview of Animal Models Related to Schizophrenia","year":2018,"lang":"en","type":"review","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":242,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; Women and Children’s Health Research Institute; University of Alberta","funders":"National Institute of Mental Health; National Institutes of Health; Canadian Institutes of Health Research; Alberta Innovates","keywords":"Endophenotype; Schizophrenia (object-oriented programming); Disease; Psychology; Psychosis; Cognition; Psychiatry; Medicine; Neuroscience; Clinical psychology; Pathology","score_opus":0.10458474892056091,"score_gpt":0.3498589078658547,"score_spread":0.2452741589452938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802046728","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008146349,0.9946921,0.000005036633,0.0010561574,0.0019024403,0.0003450379,0.00010613012,0.000008878865,0.0010695918],"genre_scores_gemma":[0.0022994787,0.9952748,0.00090319564,0.0008565421,0.00047656504,0.0000036688168,0.0000022764618,0.000085060674,0.000098414865],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99736214,0.0004978505,0.00106024,0.0002984505,0.0003524695,0.00042883723],"domain_scores_gemma":[0.99734205,0.000083389794,0.0009812844,0.000661001,0.0001071011,0.0008251747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060915196,0.0003402531,0.0010229968,0.00059046573,0.00025475724,0.00009409634,0.0018986169,0.0002545333,0.00023625897],"category_scores_gemma":[0.00014583526,0.00022418721,0.00059939246,0.00096027163,0.0002804011,0.00020802877,0.000027503464,0.0007290098,0.00008418553],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028232264,0.00024882323,0.000023391032,0.008983474,0.0004120751,0.00014490787,0.0015647591,0.000111028516,0.000055794975,0.45305365,0.064242326,0.47087744],"study_design_scores_gemma":[0.00064576726,0.0015448027,0.000044817803,0.01690686,0.00051647174,0.0012655228,0.00009193614,0.0000333396,0.000016660186,0.07317413,0.90501416,0.00074555876],"about_ca_topic_score_codex":0.00091605325,"about_ca_topic_score_gemma":0.03809035,"teacher_disagreement_score":0.8407718,"about_ca_system_score_codex":0.00010848056,"about_ca_system_score_gemma":0.007225385,"threshold_uncertainty_score":0.9984027},"labels":[],"label_agreement":null},{"id":"W2802266639","doi":"10.1111/jep.12918","title":"Lowered quality of life in mood disorders is associated with increased neuro‐oxidative stress and basal thyroid‐stimulating hormone levels and use of anticonvulsant mood stabilizers","year":2018,"lang":"en","type":"article","venue":"Journal of Evaluation in Clinical Practice","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Internal medicine; Oxidative stress; Medicine; Major depressive disorder; Pittsburgh Sleep Quality Index; Mood disorders; Mood; Malondialdehyde; Quality of life (healthcare); Bipolar disorder; Endocrinology; Psychiatry; Cognition","score_opus":0.17122570261689454,"score_gpt":0.4469372731045177,"score_spread":0.2757115704876232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802266639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978915,0.00006757857,0.00016698196,0.001233439,0.0000786644,0.00040902485,0.00003974111,0.0000039686897,0.000109135246],"genre_scores_gemma":[0.99836594,0.00016081128,0.00087308895,0.0005571667,0.000024663635,0.0000020849318,0.0000010308919,0.000013926464,0.0000012772788],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99204314,0.004359256,0.00206342,0.0003279469,0.0010197073,0.00018652236],"domain_scores_gemma":[0.9600251,0.035430744,0.003350019,0.00020623654,0.0008455995,0.00014232112],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.00880162,0.00015723673,0.000621324,0.00019611818,0.00005409891,0.000046971854,0.0001318739,0.0001265419,0.000025297939],"category_scores_gemma":[0.27719218,0.00013037455,0.000067225075,0.00054087065,0.0006294995,0.0012978296,0.00007054546,0.00054271903,3.171601e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011212043,0.0049020434,0.8463671,0.00009318119,0.00016832938,0.000009584175,0.004003189,0.0013490623,0.12958753,0.00012602279,0.00005881862,0.0021230492],"study_design_scores_gemma":[0.011042774,0.0035735168,0.96305835,0.00018816034,0.000086160224,0.0000037726752,0.0016417416,0.016608989,0.0028191872,0.0008233554,0.0000017295628,0.00015223472],"about_ca_topic_score_codex":0.00020693976,"about_ca_topic_score_gemma":0.00051105546,"teacher_disagreement_score":0.26839054,"about_ca_system_score_codex":0.000039620252,"about_ca_system_score_gemma":0.0003683097,"threshold_uncertainty_score":0.7288964},"labels":[],"label_agreement":null},{"id":"W2802384692","doi":"10.1038/s41380-018-0047-z","title":"Polyunsaturated fatty acids metabolism, purine metabolism and inosine as potential independent diagnostic biomarkers for major depressive disorder in children and adolescents","year":2018,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":181,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; National Institute for Health and Care Research","keywords":"Major depressive disorder; Metabolomics; Biomarker; Inosine; Pathophysiology; Polyunsaturated fatty acid; Internal medicine; Medicine; Bioinformatics; Fatty acid; Chemistry; Biology; Biochemistry; Adenosine","score_opus":0.004025164326059848,"score_gpt":0.2307350780693,"score_spread":0.22670991374324015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802384692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888882,0.0062801517,0.0015791706,0.0010541352,0.00077165925,0.0012157438,0.00009681607,0.000070357375,0.000043737942],"genre_scores_gemma":[0.99677473,0.00022035018,0.00073051127,0.0019400343,0.00015113872,0.0000752015,0.000028113602,0.00006311655,0.000016812695],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976526,0.00017818224,0.00034990758,0.0009271496,0.00032820154,0.0005639426],"domain_scores_gemma":[0.99919873,0.000047292953,0.00014583276,0.00034943502,0.00005055823,0.00020814892],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011171127,0.00038883789,0.00034817363,0.00030962695,0.00022957362,0.00014665884,0.00031135,0.00016560413,0.000026282669],"category_scores_gemma":[0.00041509245,0.0003620588,0.000102536884,0.0004826844,0.00038466093,0.00021551101,0.0002135889,0.00022847958,0.000010658499],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020756302,0.0017879462,0.4157494,0.00019609272,0.0003814257,0.000093519106,0.00039657828,0.000023364759,0.5564515,0.0048288926,0.00069809123,0.017317554],"study_design_scores_gemma":[0.008136286,0.00011037645,0.9162837,0.00006820151,0.00011519964,0.000120797624,0.000054751636,0.00011158769,0.0718748,0.0024784375,0.00017017293,0.00047564396],"about_ca_topic_score_codex":0.00015885876,"about_ca_topic_score_gemma":0.00008478342,"teacher_disagreement_score":0.50053436,"about_ca_system_score_codex":0.000011548637,"about_ca_system_score_gemma":0.000069538066,"threshold_uncertainty_score":0.9998831},"labels":[],"label_agreement":null},{"id":"W2802830659","doi":"10.1007/s12035-018-1051-7","title":"Major Differences in Neurooxidative and Neuronitrosative Stress Pathways Between Major Depressive Disorder and Types I and II Bipolar Disorder","year":2018,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":109,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Oxidative stress; Superoxide dismutase; Major depressive disorder; Malondialdehyde; Internal medicine; Catalase; Chemistry; Reactive oxygen species; Bipolar disorder; Endocrinology; Nitric oxide; Biochemistry; Medicine; Lithium (medication)","score_opus":0.015270899228378857,"score_gpt":0.23630135855961848,"score_spread":0.22103045933123963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802830659","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99711114,0.0011371728,0.00018853365,0.00066112727,0.00010641444,0.0004687288,0.00014934999,0.000057699894,0.00011985132],"genre_scores_gemma":[0.998574,0.00030544374,0.000046558063,0.0009180463,0.000034597808,0.000033171793,0.000010571411,0.00003906801,0.000038516122],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9974213,0.0006248891,0.00027427316,0.0010511285,0.00011365839,0.0005147005],"domain_scores_gemma":[0.9989855,0.00045750552,0.00013145768,0.00025650027,0.000033657292,0.00013532497],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006571658,0.00036998815,0.00042052765,0.00021619907,0.00038536504,0.00006743341,0.00025169674,0.00015408017,0.000021677643],"category_scores_gemma":[0.00046203338,0.00031720198,0.000035474142,0.00029891508,0.0014555806,0.00015620027,0.00060584856,0.00033985623,0.0000056228773],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013261751,0.00016844405,0.40864533,0.000047822843,0.00002740338,0.00010045443,0.0016122098,0.0000016840418,0.57809037,0.0022267003,0.000016797763,0.00893015],"study_design_scores_gemma":[0.0028221079,0.0018550314,0.8121332,0.000035936664,0.000043316893,0.00004951613,0.00025688135,0.00018678689,0.17788291,0.0030372338,0.0010678555,0.00062925264],"about_ca_topic_score_codex":0.00011246018,"about_ca_topic_score_gemma":0.00021829506,"teacher_disagreement_score":0.40348783,"about_ca_system_score_codex":0.0000062678782,"about_ca_system_score_gemma":0.00002466341,"threshold_uncertainty_score":0.999928},"labels":[],"label_agreement":null},{"id":"W2803515514","doi":"10.1016/j.toxlet.2018.05.020","title":"Inflammatory and oxidative mechanisms potentiate bifenthrin-induced neurological alterations and anxiety-like behavior in adult rats","year":2018,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Max-Planck-Gesellschaft; Albert-Ludwigs-Universität Freiburg; Bundesministerium für Bildung und Forschung","keywords":"Oxidative stress; Bifenthrin; Anxiety; Neuroscience; Mechanism (biology); Oxidative phosphorylation; Medicine; Pharmacology; Psychology; Chemistry; Endocrinology; Biology; Psychiatry; Biochemistry","score_opus":0.019536618036098557,"score_gpt":0.25586700198988804,"score_spread":0.2363303839537895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803515514","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99397665,0.000006163845,0.00015798914,0.0049394765,0.0003337332,0.00041883095,0.000006117613,0.000074235795,0.00008677822],"genre_scores_gemma":[0.9700821,0.00003207157,0.00027094228,0.029452737,0.00004207229,0.00008340594,0.0000018139959,0.000014630648,0.000020233503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984547,0.000275559,0.0002157292,0.00057172036,0.00011524556,0.00036706228],"domain_scores_gemma":[0.99951524,0.00012130463,0.00007404072,0.00016834949,0.000019005678,0.00010208903],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010355492,0.00018235004,0.00017636424,0.00016856335,0.00020999023,0.000050616363,0.00015033959,0.000116835174,0.000066553344],"category_scores_gemma":[0.0001396172,0.00017100267,0.000028700579,0.00016943553,0.00053749385,0.00019355865,0.00013945678,0.0002564698,0.00003248047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055131135,0.00008267623,0.0028413315,0.0000034114234,0.0000025491852,0.00010267478,0.00028954528,0.0000012339435,0.99373037,0.0017583496,0.00014879454,0.0009839275],"study_design_scores_gemma":[0.001893094,0.0009718191,0.21694775,0.000009096446,0.000019922385,0.00019377036,0.00011428622,0.00048524688,0.77795666,0.00070977805,0.00028110886,0.00041745225],"about_ca_topic_score_codex":0.000006407917,"about_ca_topic_score_gemma":0.00011121174,"teacher_disagreement_score":0.21577369,"about_ca_system_score_codex":0.000013832541,"about_ca_system_score_gemma":0.00001680804,"threshold_uncertainty_score":0.6973286},"labels":[],"label_agreement":null},{"id":"W2803828332","doi":"10.18433/jpps29770","title":"Licofelone Attenuates LPS-induced Depressive-like Behavior in Mice: A Possible Role for Nitric Oxide","year":2018,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Tehran University of Medical Sciences and Health Services","keywords":"Tail suspension test; Behavioural despair test; Nitric oxide synthase; Open field; Pharmacology; Nitric oxide; Chemistry; Lipopolysaccharide; Antidepressant; Internal medicine; Medicine; Hippocampus","score_opus":0.10157964954367925,"score_gpt":0.4103726827835781,"score_spread":0.3087930332398988,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803828332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99592215,0.00071106706,0.00008498652,0.0013555022,0.0006383318,0.0005039485,0.000012203541,0.000035573947,0.00073622953],"genre_scores_gemma":[0.9958571,0.00023896349,0.00070946733,0.0025639373,0.00048123352,0.000035938116,3.0196784e-7,0.000021602342,0.00009143518],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966626,0.00029331585,0.0007862282,0.00052853895,0.0008559462,0.0008733308],"domain_scores_gemma":[0.9978908,0.0009197348,0.00041923186,0.00011944382,0.00020044993,0.00045037933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012433616,0.000275093,0.00037800748,0.0005530066,0.0005302376,0.00022056435,0.0012364587,0.000063667205,0.0002900458],"category_scores_gemma":[0.00090902636,0.00021299053,0.00023328235,0.001558798,0.00084212597,0.0010365614,0.00014837208,0.00055753,0.00005440406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004006548,0.0006373732,0.009837809,0.000016779864,0.000007692429,0.00006502651,0.00018948354,0.0000134798875,0.96326774,0.00009920962,0.00045044263,0.025014296],"study_design_scores_gemma":[0.0039067804,0.0004041993,0.0061898,0.000040442792,0.000060283972,0.0002383609,0.0002612353,0.0048900214,0.9702271,0.0004751931,0.013010604,0.00029593962],"about_ca_topic_score_codex":0.000035756624,"about_ca_topic_score_gemma":0.000010851002,"teacher_disagreement_score":0.024718355,"about_ca_system_score_codex":0.000085431566,"about_ca_system_score_gemma":0.00032250327,"threshold_uncertainty_score":0.8685502},"labels":[],"label_agreement":null},{"id":"W2803835540","doi":"10.1101/327239","title":"Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Dalhousie University","funders":"Medical Research Council","keywords":"Major depressive disorder; Confounding; Depression (economics); Body mass index; Biomarker; Internal medicine; Medicine; Antidepressant; Oncology; Clinical psychology; Biology","score_opus":0.019136716003116346,"score_gpt":0.26341983039695877,"score_spread":0.24428311439384243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803835540","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99084586,0.0025939962,0.002567114,0.00007121453,0.000603041,0.0027422241,0.00039863656,0.00016736989,0.000010548025],"genre_scores_gemma":[0.99816144,0.000326162,0.00040618598,0.00033532828,0.00012194394,0.00053258106,3.1175517e-7,0.0001150651,9.806148e-7],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.995935,0.00053507753,0.0006017728,0.001877219,0.00035593013,0.0006949483],"domain_scores_gemma":[0.9970485,0.001206993,0.00053442206,0.00069037586,0.00018483803,0.0003348747],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007772099,0.000709648,0.000705294,0.00030328362,0.0003640621,0.00061066373,0.00030689524,0.00039098787,0.000013682407],"category_scores_gemma":[0.0021617126,0.00070295134,0.000095158,0.00018525792,0.00097023154,0.0005787932,0.0004959179,0.00067796564,0.0000014678677],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016480995,0.00048073358,0.69134456,0.0032855612,0.00015318609,0.00012028835,0.00019453974,0.00008789425,0.3020017,0.0004028699,0.0001504154,0.000130153],"study_design_scores_gemma":[0.0093828775,0.0001689781,0.9440334,0.0015755268,0.00015303571,6.6755416e-7,0.00007402214,0.009083326,0.03316116,0.000114278206,0.00082784594,0.0014249034],"about_ca_topic_score_codex":0.000106403146,"about_ca_topic_score_gemma":0.00004155656,"teacher_disagreement_score":0.26884055,"about_ca_system_score_codex":0.00017475245,"about_ca_system_score_gemma":0.00040838774,"threshold_uncertainty_score":0.9995422},"labels":[],"label_agreement":null},{"id":"W2804603955","doi":"10.1007/s00726-018-2579-6","title":"Characterizing amino-acid biosignatures amongst individuals with schizophrenia: a case–control study","year":2018,"lang":"en","type":"article","venue":"Amino Acids","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; Brain and Cognition Discovery Foundation; University Health Network","funders":"Peking University Health Science Center","keywords":"Amino acid; Sarcosine; Taurine; Glutamine; Chemistry; Arginine; Schizophrenia (object-oriented programming); Internal medicine; Biochemistry; Psychology; Glycine; Medicine; Psychiatry","score_opus":0.016388260893376767,"score_gpt":0.25162287759370555,"score_spread":0.23523461670032877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2804603955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965033,0.00007129915,0.0001222445,0.00025018438,0.00034121703,0.000883735,0.00011167016,0.00029783548,0.0014185313],"genre_scores_gemma":[0.99675965,0.000004144377,0.00021196884,0.002324792,0.00035762932,0.00009274063,0.0000030037236,0.00005763224,0.00018842585],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973702,0.00025946417,0.00032530227,0.00087106443,0.0005037506,0.00067024335],"domain_scores_gemma":[0.99875486,0.00017990598,0.00018697312,0.00062716444,0.00006373874,0.00018738718],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023684584,0.0004037001,0.00038157467,0.00025735993,0.00052997883,0.00026277118,0.00052828767,0.00013856897,0.00022362082],"category_scores_gemma":[0.00023357807,0.00031384948,0.00008066506,0.00066163234,0.0005826528,0.00047083313,0.00013685788,0.0003652044,0.00022333293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006163573,0.0009959292,0.06400199,0.00002515798,0.00013036981,0.0028644316,0.0061226804,6.189242e-7,0.90192777,0.00048417214,0.00045039513,0.022380153],"study_design_scores_gemma":[0.0071460744,0.0032096766,0.413426,0.00005152742,0.00010262395,0.0013464361,0.0020408002,0.000052688043,0.57028776,0.00008517796,0.0013849568,0.0008662607],"about_ca_topic_score_codex":0.000038608534,"about_ca_topic_score_gemma":0.0001357311,"teacher_disagreement_score":0.349424,"about_ca_system_score_codex":0.00003013462,"about_ca_system_score_gemma":0.000056151348,"threshold_uncertainty_score":0.99993134},"labels":[],"label_agreement":null},{"id":"W2805652711","doi":"10.1016/j.genhosppsych.2018.06.001","title":"Psychiatric comorbidity increases mortality in immune-mediated inflammatory diseases","year":2018,"lang":"en","type":"article","venue":"General Hospital Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Manitoba Health; University of Calgary; University of Manitoba","funders":"Canadian Institutes of Health Research; University of Manitoba; Research Manitoba","keywords":"Comorbidity; Psychiatric comorbidity; Immune system; Psychiatry; Medicine; Immune dysregulation; Psychology; Immunology","score_opus":0.012496435444740366,"score_gpt":0.2625693876324504,"score_spread":0.25007295218771003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805652711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907467,0.00094372506,0.000013140409,0.00066369475,0.0041002636,0.00047172882,0.00015749123,0.00030800764,0.0025952996],"genre_scores_gemma":[0.9963136,0.00015367848,0.00025805325,0.0017522669,0.0012714971,0.000047889782,0.00004015172,0.000048362304,0.00011454367],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971764,0.0002303218,0.0006040095,0.0008300409,0.00046406445,0.0006951441],"domain_scores_gemma":[0.99867946,0.00008171627,0.00020979505,0.0007087015,0.000045338144,0.0002749833],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015134244,0.00038292696,0.00034640322,0.00026491398,0.00026479346,0.000082482016,0.0006502973,0.00016135118,0.00031845382],"category_scores_gemma":[0.00031832905,0.00036770003,0.00022235778,0.00097133114,0.00054158916,0.00039133546,0.0001758959,0.00030040214,0.0005179714],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011222876,0.0015688983,0.9780914,0.00005671472,0.000015731195,0.000021901958,0.00010977498,0.000010191774,0.0053106598,0.004724251,0.009390967,0.00058727287],"study_design_scores_gemma":[0.0015304975,0.0003385335,0.98713416,0.000023736895,0.00001515483,0.0000050632184,0.00009047019,0.000222917,0.0018755588,0.0070092445,0.0012000836,0.00055460347],"about_ca_topic_score_codex":0.0004153211,"about_ca_topic_score_gemma":0.0005081476,"teacher_disagreement_score":0.009042728,"about_ca_system_score_codex":0.0000559175,"about_ca_system_score_gemma":0.00024903726,"threshold_uncertainty_score":0.9998775},"labels":[],"label_agreement":null},{"id":"W2805926644","doi":"10.71781/28380","title":"Cognition and inflammation as transdiagnostic dimensions in psychiatry","year":2016,"lang":"en","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; H. Lundbeck A/S; Ministère du Développement Économique, de l’Innovation et de l’Exportation; Sunovion; Servier; Pfizer; Canadian Institutes of Health Research; Teva Pharmaceutical Industries; AstraZeneca; Eli Lilly and Company","keywords":"Cognition; Inflammation; Psychology; Psychotherapist; Cognitive science; Medicine; Psychiatry; Internal medicine","score_opus":0.005414785243800016,"score_gpt":0.18628031603988413,"score_spread":0.1808655307960841,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805926644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9530218,0.0029839887,0.000015963979,0.0004965792,0.00095267536,0.00041761796,0.00003913439,0.00009199854,0.041980203],"genre_scores_gemma":[0.98931706,0.0014189252,0.00005367789,0.00015838414,0.00008693663,0.000035147295,0.00012446404,0.000024709276,0.008780691],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984083,0.00011357102,0.00027818492,0.00054492784,0.00037787767,0.00027714262],"domain_scores_gemma":[0.9991932,0.00022516621,0.00018995347,0.0001787589,0.00005547469,0.00015748141],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.00006992198,0.000276753,0.00022403657,0.0004018428,0.0021665543,0.000037871043,0.00016819114,0.00031469646,0.000049340968],"category_scores_gemma":[0.00021387367,0.00028267107,0.00010559019,0.00025481335,0.0001519561,0.0003462326,0.0000333909,0.00026418155,0.00008000335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001695097,0.0003213612,0.0039024667,0.0003286004,0.00006556957,0.0014303441,0.020545946,0.000106320906,0.88811076,0.06677599,0.00042790087,0.016289663],"study_design_scores_gemma":[0.009815831,0.00044922356,0.22708005,0.003308612,0.000411435,0.0015310161,0.030535614,0.00035863233,0.6753087,0.033734187,0.015024612,0.0024420947],"about_ca_topic_score_codex":0.0014031226,"about_ca_topic_score_gemma":0.005682043,"teacher_disagreement_score":0.22317758,"about_ca_system_score_codex":0.0006911275,"about_ca_system_score_gemma":0.00074985006,"threshold_uncertainty_score":0.99996257},"labels":[],"label_agreement":null},{"id":"W2805926842","doi":"10.1016/j.jad.2018.05.079","title":"Depression and anxiety symptoms are associated with prooxidant-antioxidant balance: A population-based study","year":2018,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Mashhad University of Medical Sciences; Tabriz University of Medical Sciences","keywords":"Anxiety; Depression (economics); Internal medicine; Medicine; Population; Odds ratio; Confounding; Oxidative stress; Cohort; Physiology; Psychiatry; Environmental health","score_opus":0.007844033980191319,"score_gpt":0.2507597574738307,"score_spread":0.2429157234936394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805926842","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983311,0.00007415853,0.0004978497,0.00012218967,0.0001477043,0.0005791085,0.000007208592,0.00003816505,0.00020245812],"genre_scores_gemma":[0.99962276,0.000014800906,0.000037762988,0.00021906101,0.000050390172,0.000011582933,7.120628e-7,0.000027454777,0.000015490348],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982278,0.00036685003,0.0002769059,0.00033981455,0.0005188219,0.00026980776],"domain_scores_gemma":[0.99858326,0.00034761804,0.0006243253,0.00015315757,0.00018135211,0.00011028082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000323721,0.00021657426,0.00031760757,0.00020140316,0.00027741212,0.000073979565,0.0001828687,0.00006799106,0.000020500684],"category_scores_gemma":[0.0012364276,0.00015102679,0.00008129666,0.0005568154,0.000159228,0.00031327884,0.000032508047,0.00025718496,0.0000020262544],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037997487,0.0009283765,0.9804876,0.0000114109525,0.000046461526,0.000011994358,0.00047976736,0.00009074033,0.0112693915,0.0000121684925,0.000065314176,0.006216812],"study_design_scores_gemma":[0.00409531,0.0019566065,0.9862578,0.00018025421,0.00003915577,0.000013541729,0.00074111484,0.00058573205,0.0056945058,0.00019716426,0.000029130071,0.00020972118],"about_ca_topic_score_codex":0.000030969743,"about_ca_topic_score_gemma":0.00060101494,"teacher_disagreement_score":0.0060070907,"about_ca_system_score_codex":0.00007106863,"about_ca_system_score_gemma":0.00007046162,"threshold_uncertainty_score":0.6158694},"labels":[],"label_agreement":null},{"id":"W2806019848","doi":"10.1101/338392","title":"Connectivity analyses of bioenergetic changes in schizophrenia: Identification of novel treatments","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Schizophrenia (object-oriented programming); Gene knockdown; Agonist; Biology; Transcription factor; PPAR agonist; Bioenergetics; Neuroscience; Glycolysis; Peroxisome proliferator-activated receptor; Computational biology; Receptor; Bioinformatics; Medicine; Cell biology; Gene; Genetics; Enzyme; Psychiatry; Biochemistry","score_opus":0.05168974092380378,"score_gpt":0.289288547634035,"score_spread":0.2375988067102312,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806019848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976501,0.00025703947,0.00048823896,0.00007313112,0.00051338034,0.00051620946,0.00040809117,0.00008765885,0.000006166368],"genre_scores_gemma":[0.9988569,0.00023175366,0.00064779795,0.000037020698,0.00007668036,0.000094064904,2.4665425e-7,0.000052653573,0.0000028741765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975059,0.00018408634,0.0006419024,0.0009503388,0.0003895076,0.00032828614],"domain_scores_gemma":[0.9975896,0.00015149482,0.00091054343,0.0010275594,0.00022916225,0.000091672315],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035584168,0.00038263973,0.00064121804,0.000682305,0.000058064914,0.000046229048,0.0005723685,0.00031324427,0.00002463828],"category_scores_gemma":[0.0009171137,0.0003908405,0.00013994923,0.0010382372,0.00039220872,0.00011603103,0.00029547926,0.00024225497,0.000009407558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071210015,0.00070862507,0.0025493256,0.00026398967,0.000047838676,0.000004191288,0.000012935752,0.00007599414,0.9959566,0.00029469669,0.000010881706,0.000003718409],"study_design_scores_gemma":[0.00087986083,0.00006243371,0.16044533,0.00019698282,0.00005298656,4.991993e-9,0.0000024865021,0.0005390065,0.8375431,0.0000054945167,0.000011485536,0.00026088086],"about_ca_topic_score_codex":0.00015254838,"about_ca_topic_score_gemma":0.000029139625,"teacher_disagreement_score":0.15841354,"about_ca_system_score_codex":0.00011838984,"about_ca_system_score_gemma":0.00024856185,"threshold_uncertainty_score":0.9998543},"labels":[],"label_agreement":null},{"id":"W2806431434","doi":"10.1038/s41398-018-0158-y","title":"Networks of blood proteins in the neuroimmunology of schizophrenia","year":2018,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"National Center for Advancing Translational Sciences; National Institute of Mental Health","keywords":"TIMP1; Schizophrenia (object-oriented programming); Immune system; Psychosis; Correlation; Analyte; Internal medicine; Psychology; Neuroscience; Immunology; Medicine; Endocrinology; Biology; Psychiatry; Gene expression; Chemistry; Genetics; Mathematics; Gene","score_opus":0.01971292024834846,"score_gpt":0.25832594015030064,"score_spread":0.23861301990195216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806431434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99251074,0.000319799,0.0006390031,0.002401171,0.00030136458,0.00028231132,0.000011905691,0.000014349522,0.0035193865],"genre_scores_gemma":[0.99858975,0.000011495111,0.00085096894,0.0004203203,0.00010124331,0.000007603828,0.0000018143322,0.0000073287124,0.000009462896],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.9991353,0.00012628023,0.00026131433,0.00016720078,0.00017753722,0.00013237556],"domain_scores_gemma":[0.99956584,0.00012644166,0.00008696951,0.00018977645,0.000019770936,0.000011198503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011527048,0.00007716713,0.00010553022,0.00008111942,0.00004644478,0.0000043538157,0.00030595847,0.000056709367,0.00008835057],"category_scores_gemma":[0.000030208857,0.00005866492,0.00005986,0.0004203245,0.00035425584,0.000056386907,0.000007494204,0.00014263684,0.0000055355895],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014396142,0.0020050267,0.031359702,0.0000946447,0.00003497111,0.000002665611,0.0019833776,0.0009726356,0.40248564,0.5537766,0.00030358834,0.0055415244],"study_design_scores_gemma":[0.004056579,0.00066940096,0.91879314,0.00006194658,0.000024669807,0.000028043232,0.00011142024,0.001430705,0.017606521,0.056607585,0.00040070555,0.00020930298],"about_ca_topic_score_codex":0.000011263191,"about_ca_topic_score_gemma":0.00009167042,"teacher_disagreement_score":0.8874334,"about_ca_system_score_codex":7.06379e-7,"about_ca_system_score_gemma":0.00006530161,"threshold_uncertainty_score":0.23922859},"labels":[],"label_agreement":null},{"id":"W2806727800","doi":"10.2174/1871527317666180605120244","title":"A Longitudinal Study of Alterations of S100B, sRAGE and Fas Ligand in Association to Olanzapine Medication in a Sample of First Episode Patients with Schizophrenia","year":2018,"lang":"en","type":"article","venue":"CNS & Neurological Disorders - Drug Targets","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Fas ligand; Schizophrenia (object-oriented programming); Rage (emotion); Neuroinflammation; Internal medicine; Medicine; Psychosis; Antipsychotic; Olanzapine; Receptor; Apoptosis; Autoantibody; Neuropathology; Fas receptor; Endocrinology; Oncology; Psychology; Immunology; Psychiatry; Inflammation; Neuroscience; Chemistry; Programmed cell death","score_opus":0.01408217252466871,"score_gpt":0.24793389258021145,"score_spread":0.23385172005554275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806727800","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980367,0.00002604917,0.00019484262,0.0007263927,0.00005271474,0.0008474262,0.000048073576,0.000016078962,0.000051744657],"genre_scores_gemma":[0.9995677,0.00002651806,0.00015688746,0.00016485786,0.00000955515,0.00004964041,0.000009955422,0.000010844543,0.0000040658974],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981735,0.00021907644,0.0004967907,0.0004672163,0.00038844373,0.00025500264],"domain_scores_gemma":[0.998778,0.00057670224,0.0002917481,0.0002068368,0.00007681421,0.00006994273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021386522,0.00016386047,0.00035099222,0.00026765463,0.00007317256,0.000011036163,0.00021518208,0.00006851612,0.00002655386],"category_scores_gemma":[0.002171312,0.00013361672,0.000029714749,0.0007316164,0.00019500162,0.0001362396,0.000107992346,0.00015990685,0.0000015996737],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00062962837,0.0022518,0.99273777,0.000022189544,0.0000060874436,0.0000013493026,0.0023098236,0.00012991477,0.0011945394,0.000076515884,0.000054865253,0.00058554125],"study_design_scores_gemma":[0.0035228003,0.0020719958,0.9908869,0.00002316444,0.000008564174,1.8504842e-7,0.00012297265,0.0005458231,0.0020341421,0.0006262728,0.0000378453,0.00011932845],"about_ca_topic_score_codex":0.00043822912,"about_ca_topic_score_gemma":0.014186661,"teacher_disagreement_score":0.013748432,"about_ca_system_score_codex":0.000018803588,"about_ca_system_score_gemma":0.00001749509,"threshold_uncertainty_score":0.791649},"labels":[],"label_agreement":null},{"id":"W2807729355","doi":"10.3389/fpsyt.2018.00299","title":"Biological Mechanisms of Cancer-Induced Depression","year":2018,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Prostate Cancer Canada","keywords":"Depression (economics); Cancer; Context (archaeology); Medicine; Major depressive disorder; Population; Excitotoxicity; Psychiatry; Bioinformatics; Psychology; Neuroscience; Glutamate receptor; Internal medicine; Biology; Mood","score_opus":0.05811974029521325,"score_gpt":0.3418094166487702,"score_spread":0.2836896763535569,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807729355","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021402938,0.97381413,0.0009640105,0.00002791308,0.023348138,0.0006365109,0.00006663541,0.000062486775,0.00086614274],"genre_scores_gemma":[0.00021898506,0.99400806,0.0050993003,0.00018805382,0.0002445872,0.00011447063,0.000008470752,0.000049004444,0.00006908687],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975117,0.0003309439,0.0006652752,0.0008369782,0.0002464181,0.0004087217],"domain_scores_gemma":[0.9988282,0.000066645305,0.0004922759,0.000511867,0.000013831909,0.0000872327],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016739794,0.0004079087,0.0013008937,0.00039242892,0.0000669189,0.00001649563,0.0008939106,0.00062635,0.00009944812],"category_scores_gemma":[0.00014961143,0.0002992164,0.0004202824,0.000757823,0.00016403101,0.000058437017,0.00014350192,0.00045281503,0.000026136504],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037239028,0.0002462339,0.00035008285,0.004296599,0.000032861528,0.0000051921247,0.000026980046,2.0305139e-7,0.00012937032,0.0018073758,0.05096939,0.9420985],"study_design_scores_gemma":[0.0008722862,0.0002499104,0.00009413291,0.015056027,0.00012187447,0.000013293465,0.000082237566,0.000017659686,0.0011598958,0.028240392,0.95311683,0.0009754522],"about_ca_topic_score_codex":0.00001880268,"about_ca_topic_score_gemma":0.000015187786,"teacher_disagreement_score":0.941123,"about_ca_system_score_codex":0.00006708897,"about_ca_system_score_gemma":0.00031730792,"threshold_uncertainty_score":0.999946},"labels":[],"label_agreement":null},{"id":"W2808530830","doi":"10.1515/revneuro-2018-0027","title":"Therapeutic potential of JAK/STAT pathway modulation in mood disorders","year":2018,"lang":"en","type":"review","venue":"Reviews in the Neurosciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto Western Hospital; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"stat; Janus kinase; JAK-STAT signaling pathway; Mood disorders; Signal transduction; Antidepressant; STAT6; Medicine; Neuroscience; Biology; Immunology; Cytokine; STAT3; Cell biology; Interleukin 4; Tyrosine kinase; Psychiatry; Anxiety; Hippocampus","score_opus":0.09167598037319936,"score_gpt":0.3474493878367612,"score_spread":0.25577340746356186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808530830","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00036714177,0.9944226,0.000052499447,0.00007774086,0.0016514374,0.002368697,0.000018618175,0.000021321257,0.0010199437],"genre_scores_gemma":[0.012627717,0.98672885,0.000020564446,0.00026629487,0.000063742,0.00017238113,0.000002845723,0.000028019827,0.00008959299],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9937551,0.002762587,0.0013158971,0.0009797628,0.00066480716,0.0005218663],"domain_scores_gemma":[0.9976858,0.0006333273,0.00086718536,0.0007563958,0.000011811224,0.000045477038],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017596304,0.000477967,0.0014096014,0.00046051544,0.00013782232,0.00009936759,0.0021816404,0.00015791226,0.000027793982],"category_scores_gemma":[0.0011055638,0.0002727437,0.00051993027,0.0029006915,0.00080911454,0.000281122,0.00014655307,0.00046507944,0.00005577769],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000035723226,0.0002330669,0.000011546048,0.0030607632,0.0000010113132,0.000003651563,0.00021087719,0.000014904912,0.00030407542,0.0005413221,0.000044869917,0.99557036],"study_design_scores_gemma":[0.00023037611,0.00022030086,0.00019882535,0.004813115,0.000036007637,0.000032929136,0.000054049982,0.00034545246,0.000048793976,0.002323695,0.99123675,0.00045969896],"about_ca_topic_score_codex":0.000018284285,"about_ca_topic_score_gemma":0.00010921378,"teacher_disagreement_score":0.99511063,"about_ca_system_score_codex":0.00003554579,"about_ca_system_score_gemma":0.00015578055,"threshold_uncertainty_score":0.99997246},"labels":[],"label_agreement":null},{"id":"W2808718833","doi":"10.1503/jpn.170192","title":"Abnormal protein and mRNA expression of inflammatory cytokines in the prefrontal cortex of depressed individuals who died by suicide","year":2018,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health","keywords":"Lymphotoxin; Proinflammatory cytokine; Prefrontal cortex; Internal medicine; Endocrinology; Tumor necrosis factor alpha; Cytokine; Interleukin; Medicine; Antidepressant; Hippocampus; Inflammation; Immunology; Psychiatry","score_opus":0.014897945260564545,"score_gpt":0.2586011946165774,"score_spread":0.24370324935601284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808718833","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986277,0.000345211,0.000054862343,0.0003409829,0.00026308943,0.00020269047,0.000014058123,0.0000037968061,0.00014761617],"genre_scores_gemma":[0.99924916,0.00012757393,0.00014796307,0.0003923116,0.000055280412,0.000002549706,7.850146e-8,0.000006212742,0.00001884228],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838525,0.00021819763,0.00051025226,0.00022666884,0.00046266455,0.00019695841],"domain_scores_gemma":[0.9989934,0.00012324113,0.0006119068,0.00015896204,0.000038941987,0.000073577634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049692905,0.00012713626,0.00022237898,0.00014165438,0.0001300655,0.00004093332,0.00048312117,0.000051457566,0.0000058465193],"category_scores_gemma":[0.00032824776,0.00008179661,0.000045404984,0.00029703783,0.000854615,0.0004945452,0.00008831431,0.00021091294,1.5211283e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014315528,0.0001319766,0.059279792,0.00004460329,6.2566517e-7,0.0000039069573,0.00047170382,0.0000027233643,0.9392935,0.0002111018,0.00018632135,0.00023060113],"study_design_scores_gemma":[0.00075572863,0.0006712796,0.454591,0.00017334685,0.0000043197365,0.00008046405,0.00018293444,0.000039181403,0.5427223,0.0005430945,0.00015853463,0.000077808254],"about_ca_topic_score_codex":0.000005975015,"about_ca_topic_score_gemma":0.000014973215,"teacher_disagreement_score":0.39657116,"about_ca_system_score_codex":0.0000030759898,"about_ca_system_score_gemma":0.000079308295,"threshold_uncertainty_score":0.33355686},"labels":[],"label_agreement":null},{"id":"W2809400156","doi":"10.1016/j.bbi.2018.06.019","title":"Associations between chronic caregiving stress and T cell markers implicated in immunosenescence","year":2018,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health","keywords":"Immunosenescence; CD8; Chronic stress; Immunology; Immune system; Neurotypical; Cytotoxic T cell; T cell; Psychology; Medicine; Internal medicine; Biology; Autism; Genetics; Autism spectrum disorder; Psychiatry; In vitro","score_opus":0.026612286738519866,"score_gpt":0.2849912633167915,"score_spread":0.25837897657827164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809400156","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983875,0.00017500023,0.000012689489,0.00018276196,0.00006342436,0.00028912508,0.00013485595,0.000056040186,0.0006986045],"genre_scores_gemma":[0.99955046,0.000091169575,0.000021780521,0.00011187743,0.000033387598,0.000019656878,0.00002115408,0.00001638927,0.00013411969],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987412,0.00024796184,0.00022273716,0.00032000564,0.0001264698,0.00034161497],"domain_scores_gemma":[0.99912935,0.00038834682,0.00009101558,0.00028302238,0.000029321582,0.000078933765],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002263187,0.00015692903,0.00018878457,0.000113291055,0.00040876068,0.00008968567,0.00023675946,0.000104086364,0.000034864413],"category_scores_gemma":[0.00025275178,0.00016320703,0.000031166514,0.00034423577,0.00039495138,0.00020694049,0.000189594,0.0002778784,0.000007218022],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000127826615,0.00014923139,0.3805064,0.00002248352,0.0000026081666,0.000004751761,0.0011690586,1.6012415e-7,0.5966783,0.00004892196,0.00011168122,0.021293616],"study_design_scores_gemma":[0.00061152497,0.000108593704,0.90124786,0.00003021678,0.000008748191,0.0000025215656,0.00030196767,0.000010211379,0.09735621,0.00003539478,0.00011062323,0.00017612586],"about_ca_topic_score_codex":0.0012043102,"about_ca_topic_score_gemma":0.0004312982,"teacher_disagreement_score":0.52074146,"about_ca_system_score_codex":0.00007858495,"about_ca_system_score_gemma":0.00005659636,"threshold_uncertainty_score":0.66553897},"labels":[],"label_agreement":null},{"id":"W2810746661","doi":"10.1093/ijnp/pyw043.116","title":"PS116. Desvenlafaxine prevents white matter injury and improves the decreased phosphorylation of rate-limiting enzyme of cholesterol synthesis in a chronic mouse model of depression.","year":2016,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Manitoba; University of Alberta; University of Saskatchewan","funders":"","keywords":"Depression (economics); Limiting; Phosphorylation; White matter; Medicine; Internal medicine; Pharmacology; Chemistry; Biochemistry","score_opus":0.019459983280749354,"score_gpt":0.290195324770439,"score_spread":0.2707353414896897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2810746661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971289,0.000082250575,0.00036405763,0.0019440395,0.00022574472,0.00016966385,0.000028486844,0.0000030355113,0.000053792704],"genre_scores_gemma":[0.99861485,0.00038512808,0.000043214837,0.00080735073,0.000051201037,0.000009082679,1.1972242e-7,0.000015304655,0.0000737399],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836546,0.00038332207,0.0006583704,0.00015778754,0.0002993214,0.00013574662],"domain_scores_gemma":[0.99778444,0.000974019,0.00093752355,0.00013597513,0.00012927488,0.0000387847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044850667,0.000117153846,0.00021735289,0.00018829053,0.000027317994,0.000009599043,0.0006972546,0.000040087867,0.00009638298],"category_scores_gemma":[0.0003584751,0.00006235559,0.000088076034,0.00010468853,0.00026206436,0.0001932072,0.000110382614,0.00016656061,0.0000014527129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014066575,0.00014350796,0.0036116436,0.000015878799,0.000032361222,0.0000029808748,0.00016221723,0.0010099851,0.98779005,0.00001920261,0.00013228582,0.0056732497],"study_design_scores_gemma":[0.0018962999,0.00012740042,0.047624543,0.00012312723,0.00002400597,0.000029381856,0.000019292038,0.0032726473,0.9464567,0.0003543917,0.000014893733,0.00005736131],"about_ca_topic_score_codex":0.000006032429,"about_ca_topic_score_gemma":0.0000024671308,"teacher_disagreement_score":0.0440129,"about_ca_system_score_codex":0.00003907067,"about_ca_system_score_gemma":0.00008584441,"threshold_uncertainty_score":0.25427872},"labels":[],"label_agreement":null},{"id":"W2810796301","doi":"10.1016/j.drugalcdep.2018.05.021","title":"Normal glutathione levels in autopsied brain of chronic users of heroin and of cocaine","year":2018,"lang":"en","type":"article","venue":"Drug and Alcohol Dependence","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; London Health Sciences Centre; Western University; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; Centre for Addiction and Mental Health Foundation","keywords":"Heroin; Heroin dependence; Psychology; Glutathione; Medicine; Pharmacology; Drug; Chemistry; Biochemistry","score_opus":0.028566596699507448,"score_gpt":0.2825252576209284,"score_spread":0.25395866092142094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2810796301","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984989,0.0002313363,0.000088021596,0.00026602205,0.000051944062,0.00015070912,0.000036109774,0.000010980292,0.000665955],"genre_scores_gemma":[0.9994323,0.00008286448,0.000132805,0.00015466673,0.000015479996,0.000002668571,5.8188266e-7,0.000008252928,0.00017033023],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998892,0.000089006055,0.00031243713,0.00028019107,0.00022348885,0.00020287666],"domain_scores_gemma":[0.9993113,0.00027075072,0.00015844563,0.00017042729,0.000034822944,0.00005423591],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030302294,0.000111063135,0.00024657042,0.00012034707,0.000037294798,0.000007873222,0.00017609997,0.00005056936,0.000041816176],"category_scores_gemma":[0.00027736928,0.000105102874,0.000028861408,0.00029842157,0.0006754466,0.00017297744,0.000098629396,0.00009923988,0.0000020703471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008173641,0.00010475371,0.0045147594,0.00013608654,0.000004288595,0.000008295169,0.0018877694,0.000018529727,0.98554265,0.0017852045,0.000055387558,0.005860534],"study_design_scores_gemma":[0.0017147932,0.00030178338,0.08499091,0.00013249261,0.0000044471913,0.000021666197,0.00041868852,0.001775433,0.9098546,0.0005879959,0.00005656894,0.00014065237],"about_ca_topic_score_codex":0.00016459584,"about_ca_topic_score_gemma":0.00033611624,"teacher_disagreement_score":0.08047615,"about_ca_system_score_codex":0.000010532368,"about_ca_system_score_gemma":0.00007085162,"threshold_uncertainty_score":0.4285971},"labels":[],"label_agreement":null},{"id":"W2814803529","doi":"10.1136/rmdopen-2018-000670","title":"Depression as a risk factor for the development of rheumatoid arthritis: a population-based cohort study","year":2018,"lang":"en","type":"article","venue":"RMD Open","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Major depressive disorder; Rheumatoid arthritis; Internal medicine; Cohort; Proportional hazards model; Population; Depression (economics); Confounding; Risk factor; Cohort study; Body mass index; Oncology","score_opus":0.03627488044701064,"score_gpt":0.31995968615594306,"score_spread":0.2836848057089324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2814803529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99544966,0.000037114136,0.0010252666,0.000041668132,0.00012346974,0.002715169,0.00003060281,0.00002447871,0.0005525874],"genre_scores_gemma":[0.9986883,0.000015580963,0.00073951925,0.00016809606,0.00001278938,0.00027928033,0.0000023098025,0.000013155925,0.00008096898],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990039,0.000091098445,0.00024602935,0.00028415595,0.00022775476,0.00014707215],"domain_scores_gemma":[0.99910307,0.00038464085,0.00014897542,0.0002856411,0.00004034951,0.000037329562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027458536,0.00009287526,0.00014416686,0.000032742006,0.00042893612,0.00008319371,0.00053512194,0.0000269721,0.00038114042],"category_scores_gemma":[0.0006769484,0.00006198324,0.000033056505,0.00013162922,0.00004653017,0.000106672356,0.00014096126,0.000047902195,0.000041676867],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032126045,0.0004877638,0.8597728,0.000009690187,0.00002581973,6.6320627e-7,0.003464665,0.000022530825,0.0038023589,0.00006244758,0.0002470539,0.13178295],"study_design_scores_gemma":[0.0017177389,0.00013960022,0.9459248,0.000043547512,0.0000023795424,4.8642306e-7,0.00036211318,0.00041527054,0.0482361,0.00016712218,0.0028786107,0.000112220805],"about_ca_topic_score_codex":0.00038769466,"about_ca_topic_score_gemma":0.0012746217,"teacher_disagreement_score":0.13167073,"about_ca_system_score_codex":0.000017602282,"about_ca_system_score_gemma":0.00011674583,"threshold_uncertainty_score":0.41732204},"labels":[],"label_agreement":null},{"id":"W2821883019","doi":"10.71781/31988","title":"Le stress protéotoxique : le prix à payer pour la tolérance au soi immunitaire","year":2018,"lang":"fr","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Medicine","score_opus":0.00609079160680289,"score_gpt":0.18544134927484837,"score_spread":0.17935055766804547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2821883019","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83580935,0.004773305,0.00053686375,0.0011685346,0.0014757675,0.001114568,0.00016072056,0.00021748427,0.15474337],"genre_scores_gemma":[0.8697618,0.00028827772,0.00060973014,0.00018255929,0.00027003518,0.00009654008,0.00018422712,0.00007462082,0.12853217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959484,0.0006170536,0.0005552464,0.0011752681,0.00082026114,0.0008838104],"domain_scores_gemma":[0.99755824,0.00027670414,0.0006058466,0.00075206236,0.0003757082,0.0004314629],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0002597612,0.000737287,0.000558112,0.00033757632,0.012248091,0.00016733396,0.0011757278,0.00081116665,0.00006812829],"category_scores_gemma":[0.00027011556,0.0008946334,0.00047436627,0.00058368105,0.0012170256,0.00085709133,0.00031309976,0.00086638884,0.00023741566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021069942,0.0026174767,0.00839896,0.0011992977,0.00039895912,0.005297467,0.09537447,0.0017140252,0.55352193,0.31509262,0.0023203928,0.011957417],"study_design_scores_gemma":[0.0039759157,0.00026103764,0.060949087,0.001466003,0.00016222346,0.0013267641,0.07026111,0.0016820969,0.670952,0.0013222058,0.18592286,0.0017186644],"about_ca_topic_score_codex":0.067150496,"about_ca_topic_score_gemma":0.048188265,"teacher_disagreement_score":0.31377044,"about_ca_system_score_codex":0.002775343,"about_ca_system_score_gemma":0.012350162,"threshold_uncertainty_score":0.9993504},"labels":[],"label_agreement":null},{"id":"W2839463924","doi":"10.1016/j.cellimm.2018.07.001","title":"Autocrine GABA signaling distinctively regulates phenotypic activation of mouse pulmonary macrophages","year":2018,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Autocrine signalling; Phenotype; Biology; Cell biology; Signal transduction; Receptor; Phenotypic switching; Genetics; Gene","score_opus":0.018232723359738683,"score_gpt":0.23441221354949954,"score_spread":0.21617949018976085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2839463924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952071,0.00023547473,0.0023918857,0.00017919854,0.00022159163,0.00018979891,0.000010916646,0.00011782201,0.0014462513],"genre_scores_gemma":[0.9980028,0.000018538918,0.00020306563,0.00010737191,0.00007999498,0.000011175985,0.000012205508,0.000029015551,0.001535794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871284,0.00016482569,0.00027239358,0.00039731435,0.00013083029,0.0003218169],"domain_scores_gemma":[0.99921423,0.00017575496,0.00018369313,0.00033786174,0.00005737215,0.0000310757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008279502,0.00017159276,0.00021608565,0.00013780831,0.00017398693,0.000015535526,0.00032716102,0.0001056394,0.0004294272],"category_scores_gemma":[0.00030510826,0.00016402775,0.00007056896,0.0002986253,0.0007747025,0.00014645056,0.00013505235,0.00015287178,0.00012546664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018126416,0.00013641083,0.000067459725,0.000018818582,0.000014411213,0.000011038331,0.00020200331,0.0000113330525,0.9925036,0.0030056273,0.000029705216,0.003818335],"study_design_scores_gemma":[0.00037474462,0.00018847238,0.0025321876,0.000016263597,0.0000061972046,0.000011737878,0.0001092322,0.00040443844,0.9925143,0.0028176096,0.0008664394,0.00015836168],"about_ca_topic_score_codex":0.000021138798,"about_ca_topic_score_gemma":0.0000010689225,"teacher_disagreement_score":0.0036599734,"about_ca_system_score_codex":0.000030572955,"about_ca_system_score_gemma":0.00003247092,"threshold_uncertainty_score":0.6688857},"labels":[],"label_agreement":null},{"id":"W2883368938","doi":"10.1016/j.biopsych.2018.07.010","title":"Transcriptomic Evidence for Alterations in Astrocytes and Parvalbumin Interneurons in Subjects With Bipolar Disorder and Schizophrenia","year":2018,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":126,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of General Medical Sciences; National Institute of Mental Health; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Bureau of Meteorology, Australian Government; F. Hoffmann-La Roche","keywords":"Parvalbumin; Schizophrenia (object-oriented programming); Neuroscience; Bipolar disorder; Transcriptome; Biology; Gene expression; Astrocyte; Psychology; Gene; Genetics; Central nervous system; Psychiatry; Cognition","score_opus":0.10478466454740261,"score_gpt":0.3443417652138482,"score_spread":0.2395571006664456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883368938","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.121105485,0.87704545,0.00010617757,0.00014268965,0.00024148925,0.0012427152,0.00006611946,0.00003818056,0.000011676508],"genre_scores_gemma":[0.028663678,0.9696978,0.00095766585,0.00021533527,0.00010463838,0.00029398495,0.000012865222,0.000030890562,0.000023142566],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977345,0.0003297089,0.00046868078,0.000990597,0.000086508255,0.00039003498],"domain_scores_gemma":[0.99879104,0.00074426946,0.0001408366,0.00022006509,0.000008882016,0.000094892675],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001809192,0.00041372102,0.00078472274,0.00024901415,0.000092090275,0.00008407882,0.00030517761,0.00027591482,0.000011851598],"category_scores_gemma":[0.0004099648,0.00026465819,0.00011949403,0.00038861533,0.0004613992,0.00013862464,0.00006437591,0.00037975822,0.000006711038],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040381392,0.0019722446,0.051997546,0.020689687,0.00009116809,0.000037486487,0.0006476941,0.0000022904042,0.0010192777,0.012766958,0.0007804563,0.90595704],"study_design_scores_gemma":[0.0095551675,0.0072034793,0.031483553,0.04680254,0.00027749655,0.0003248081,0.00030495774,0.00017628277,0.00013007839,0.0031703406,0.8969993,0.0035720125],"about_ca_topic_score_codex":0.000018912539,"about_ca_topic_score_gemma":0.0011738592,"teacher_disagreement_score":0.90238506,"about_ca_system_score_codex":0.00002246553,"about_ca_system_score_gemma":0.00013637653,"threshold_uncertainty_score":0.99998057},"labels":[],"label_agreement":null},{"id":"W2883735540","doi":"10.1016/b978-0-12-801238-3.96846-6","title":"Studying the Role of D 4 Receptors in Psychiatric Illnesses and Related Functions With L-745,870","year":2018,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Psychiatry; Psychology; Neuroscience","score_opus":0.013068614682826947,"score_gpt":0.21845344676034822,"score_spread":0.20538483207752128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883735540","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.023254273,0.0013703384,6.000753e-7,0.00007165046,0.00051942933,0.00065447815,0.000012728088,0.000049840302,0.9740667],"genre_scores_gemma":[0.1843086,0.00025345475,0.000033168213,0.00017684643,0.00009114096,0.000038975533,0.0000025940844,0.000079657744,0.81501555],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99855685,0.00006937334,0.00036887662,0.000499068,0.0002811409,0.0002246928],"domain_scores_gemma":[0.99902,0.00019408503,0.00027737502,0.0004140645,0.00004120135,0.000053308955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016565513,0.00029637697,0.00032945332,0.00025757283,0.00020381324,0.00003426312,0.00027229733,0.00017644155,0.0003173018],"category_scores_gemma":[0.00006084571,0.00019361996,0.000078639445,0.00009956507,0.0005913915,0.0000523189,0.000098338125,0.00042410975,0.000052736606],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009572882,0.00004283524,0.00029281326,0.00006468696,0.000045467288,0.000007305189,0.0024863817,0.0000023186137,0.00054713845,0.0055314493,0.00019732313,0.99068654],"study_design_scores_gemma":[0.00087479607,0.00037746946,0.00033367865,0.00036315335,0.00009051471,0.00004410797,0.0008692084,0.00000801267,0.001154148,0.028825695,0.96652514,0.0005340844],"about_ca_topic_score_codex":0.0000018468176,"about_ca_topic_score_gemma":0.00010388335,"teacher_disagreement_score":0.9901525,"about_ca_system_score_codex":0.000022093845,"about_ca_system_score_gemma":0.00008373358,"threshold_uncertainty_score":0.7895593},"labels":[],"label_agreement":null},{"id":"W2884480452","doi":"10.1007/s12640-018-9937-8","title":"Eotaxin, an Endogenous Cognitive Deteriorating Chemokine (ECDC), Is a Major Contributor to Cognitive Decline in Normal People and to Executive, Memory, and Sustained Attention Deficits, Formal Thought Disorders, and Psychopathology in Schizophrenia Patients","year":2018,"lang":"en","type":"article","venue":"Neurotoxicity Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Asahi Glass Foundation","keywords":"Eotaxin; Psychology; Schizophrenia (object-oriented programming); Psychopathology; Cognition; Cognitive skill; Effects of sleep deprivation on cognitive performance; Psychiatry; Medicine; Immunology; Chemokine","score_opus":0.03568328209507651,"score_gpt":0.3333260851933705,"score_spread":0.29764280309829394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884480452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949006,0.000032954777,0.0001343272,0.00065635674,0.000057984256,0.003694075,0.0002369763,0.000035520192,0.0002512328],"genre_scores_gemma":[0.9976171,0.00007003758,0.000118611286,0.0016971021,0.00005883796,0.0003519537,0.000016480588,0.00003993004,0.000029903676],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.995843,0.0008941156,0.00044340442,0.001153419,0.0005422192,0.001123836],"domain_scores_gemma":[0.99818593,0.000788458,0.00008707115,0.0001906778,0.0003611355,0.00038674843],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00096660166,0.0003056522,0.00040440957,0.00075624895,0.00049689587,0.00019923707,0.00023318725,0.00014653434,0.000025784602],"category_scores_gemma":[0.004389242,0.0003112729,0.000029199546,0.0013358725,0.0005073197,0.000548823,0.0007920034,0.00055284833,0.000015238241],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018273212,0.0014659618,0.3961341,0.0001677905,0.000008942671,0.00015023949,0.010888053,6.1571103e-7,0.51123065,0.00009077805,0.00004727095,0.061542396],"study_design_scores_gemma":[0.014602513,0.0058495575,0.8774328,0.00014888178,0.000007778158,0.00006413968,0.0032154045,0.00058521435,0.09736367,0.00020745948,0.000046440895,0.00047609827],"about_ca_topic_score_codex":0.00031741266,"about_ca_topic_score_gemma":0.0077478234,"teacher_disagreement_score":0.48129874,"about_ca_system_score_codex":0.000046456043,"about_ca_system_score_gemma":0.00007706728,"threshold_uncertainty_score":0.99993396},"labels":[],"label_agreement":null},{"id":"W2884516035","doi":"10.3389/fnins.2018.00483","title":"Implications of Systemic Inflammation and Periodontitis for Major Depression","year":2018,"lang":"en","type":"review","venue":"Frontiers in Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of British Columbia","keywords":"Medicine; Periodontitis; Neuroinflammation; Systemic inflammation; Inflammation; Depression (economics); Immunology; Rheumatoid arthritis; Disease; Population; Internal medicine","score_opus":0.04129034549961223,"score_gpt":0.3109827893411095,"score_spread":0.26969244384149726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884516035","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007578822,0.98459524,0.010412721,0.000035904726,0.0016251586,0.002080057,0.00016409197,0.000048502618,0.00028043345],"genre_scores_gemma":[0.0019447105,0.9962053,0.0012200695,0.00004608305,0.000056962246,0.0003271848,0.000005402899,0.00003105604,0.00016323366],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99792933,0.00015507001,0.00057250046,0.000842982,0.00019367835,0.00030646115],"domain_scores_gemma":[0.9988218,0.00018289013,0.00046066826,0.0004269378,0.0000332221,0.000074512456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022784936,0.0002470099,0.0007094733,0.00043651898,0.00017414692,0.00007352402,0.00068295415,0.00015708616,0.000001926241],"category_scores_gemma":[0.0011473277,0.00021507639,0.00014034928,0.0007734759,0.0005428162,0.00025286045,0.00014407466,0.00014050586,0.0000017170863],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000119669285,0.000042363634,0.00031683687,0.0104153985,0.000001996592,0.0000026642165,0.00019120146,0.000002105761,0.007726103,0.0008150456,0.0030443955,0.9774299],"study_design_scores_gemma":[0.0006011607,0.00015473326,0.0005843896,0.009278962,0.0000782767,0.0001668195,0.00005749542,0.00042704062,0.0021351594,0.0011155613,0.98478293,0.00061745837],"about_ca_topic_score_codex":0.000002961892,"about_ca_topic_score_gemma":0.0000025767895,"teacher_disagreement_score":0.98173857,"about_ca_system_score_codex":0.000052842384,"about_ca_system_score_gemma":0.00015248137,"threshold_uncertainty_score":0.87705606},"labels":[],"label_agreement":null},{"id":"W2885803960","doi":"10.1016/j.cyto.2018.07.036","title":"Interleukin (IL)-8 polymorphisms contribute in suicide behavior","year":2018,"lang":"en","type":"article","venue":"Cytokine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg","funders":"","keywords":"Psychology; Medicine","score_opus":0.03096945266186099,"score_gpt":0.286633437944162,"score_spread":0.25566398528230105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885803960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99470115,0.00003679643,0.00015567022,0.0007259092,0.00040824708,0.00024083648,0.000060196002,0.00011021868,0.003560982],"genre_scores_gemma":[0.9967043,0.000009534134,0.00006340829,0.0020728025,0.000156348,0.000033771852,0.0000042774795,0.000021059837,0.000934491],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987251,0.00006201834,0.00025690635,0.00037383346,0.00017863195,0.00040350074],"domain_scores_gemma":[0.9994411,0.00009118243,0.000064405904,0.0002904005,0.000024956478,0.0000879809],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012058592,0.00014737628,0.00017494817,0.00015535209,0.000070231974,0.00004059147,0.00033265023,0.00006944738,0.0006516077],"category_scores_gemma":[0.0005285957,0.00013573313,0.000054961944,0.0004065423,0.00028923916,0.0001353403,0.00009956096,0.00014890796,0.0005755131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081615566,0.00017291332,0.00847748,0.000002974221,0.0000013138147,0.00013956841,0.00020517746,4.4244933e-7,0.9814939,0.0020577474,0.0016498109,0.005717049],"study_design_scores_gemma":[0.0011891822,0.00020923754,0.05027399,0.000035058707,0.00000433014,0.00004758382,0.00003333218,0.00006215159,0.9359361,0.00044939606,0.011542667,0.00021698604],"about_ca_topic_score_codex":0.000089722,"about_ca_topic_score_gemma":0.0003679996,"teacher_disagreement_score":0.04555782,"about_ca_system_score_codex":0.000052568,"about_ca_system_score_gemma":0.000030129258,"threshold_uncertainty_score":0.7397249},"labels":[],"label_agreement":null},{"id":"W2885922534","doi":"10.1523/eneuro.0249-18.2018","title":"Prospective Analysis of the Effects of Maternal Immune Activation on Rat Cytokines during Pregnancy and Behavior of the Male Offspring Relevant to Schizophrenia","year":2018,"lang":"en","type":"article","venue":"eNeuro","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada; University of Saskatchewan","keywords":"Offspring; CXCL1; Cytokine; Sickness behavior; Pregnancy; Endocrinology; Psychology; Internal medicine; Maternal deprivation; Immune system; Physiology; Developmental psychology; Medicine; Immunology; Chemokine; Biology","score_opus":0.007697938071194254,"score_gpt":0.23051814528327796,"score_spread":0.2228202072120837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885922534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992861,0.000013539263,0.0000046900172,0.000045666977,0.00017028398,0.00038853553,0.0000054191037,0.000008337044,0.00007743397],"genre_scores_gemma":[0.9997721,0.000009108333,0.00001747124,0.00002142567,0.000012177019,0.00001804424,6.499082e-8,0.000009063391,0.00014055667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923265,0.00008371521,0.00017216154,0.00020397542,0.00020858526,0.00009891916],"domain_scores_gemma":[0.9993292,0.0001239341,0.00018153762,0.0003163487,0.000032991473,0.000015990141],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002744771,0.00008639294,0.0001556679,0.00010684608,0.00008597008,0.000008769573,0.00022276955,0.000021308662,0.000007667535],"category_scores_gemma":[0.00045812887,0.000052179836,0.00008338533,0.00061478117,0.00014222514,0.00005543464,0.00014250305,0.000065871034,5.6746495e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010960781,0.00006543242,0.04954863,0.000058433685,0.00001243558,9.503492e-7,0.0003165755,0.000024361567,0.949194,0.00012565029,6.0413424e-7,0.00054332195],"study_design_scores_gemma":[0.00018498642,0.000062410014,0.49055463,0.00014320148,0.000034072902,0.0000010120328,0.000004769695,0.000012281043,0.5089677,0.000010635167,4.924474e-7,0.000023822997],"about_ca_topic_score_codex":0.000023492821,"about_ca_topic_score_gemma":0.000013734365,"teacher_disagreement_score":0.441006,"about_ca_system_score_codex":0.000010038901,"about_ca_system_score_gemma":0.0000097457905,"threshold_uncertainty_score":0.21278319},"labels":[],"label_agreement":null},{"id":"W2885956288","doi":"10.1111/ejn.14123","title":"Cocaine self‐administration is increased after frontal traumatic brain injury and associated with neuroinflammation","year":2018,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Institute of Neurosciences, Mental Health and Addiction; Canadian Institutes of Health Research; Health Canada; National Institute of Neurological Disorders and Stroke; Shire; Michael Smith Health Research BC","keywords":"Neuroinflammation; Traumatic brain injury; Psychology; Neuroscience; Administration (probate law); Medicine; Psychiatry; Political science; Internal medicine; Inflammation","score_opus":0.021934967069471612,"score_gpt":0.25205241608457113,"score_spread":0.2301174490150995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885956288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99683446,0.000010100726,0.0005507704,0.0011842,0.00022301568,0.00013989411,0.000010911257,0.000049376813,0.0009972715],"genre_scores_gemma":[0.9950633,0.0000123576165,0.00019059597,0.0044953064,0.000108888824,8.657167e-7,3.7043003e-7,0.00002702093,0.000101306185],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976373,0.00074202934,0.00045416373,0.00034476447,0.0005547772,0.0002670209],"domain_scores_gemma":[0.99882275,0.00018902197,0.00050648046,0.00018063873,0.000106157415,0.00019493741],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072316144,0.00018645533,0.00018068997,0.00017711989,0.00022637584,0.00023315387,0.00035162247,0.00001994383,0.000027223477],"category_scores_gemma":[0.0016027631,0.00014608691,0.000049026763,0.0004868808,0.00053181924,0.00073768833,0.00005581482,0.00022712167,0.000018442342],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003993811,0.00019341806,0.00062971644,0.000011534145,0.0000030129806,0.0005165235,0.0018375638,0.000001867589,0.994026,0.0000463277,0.0006454006,0.0016892388],"study_design_scores_gemma":[0.0021449483,0.0069415458,0.8708661,0.00016954214,0.00002642964,0.0009960087,0.00010901878,0.002214196,0.113690704,0.0000776263,0.0023821883,0.00038166792],"about_ca_topic_score_codex":7.0943e-7,"about_ca_topic_score_gemma":0.0000043639266,"teacher_disagreement_score":0.88033533,"about_ca_system_score_codex":0.00002407926,"about_ca_system_score_gemma":0.00009611334,"threshold_uncertainty_score":0.5957251},"labels":[],"label_agreement":null},{"id":"W2886221328","doi":"10.1016/j.pbb.2018.08.005","title":"Single administration of agmatine reverses the depressive-like behavior induced by corticosterone in mice: Comparison with ketamine and fluoxetine","year":2018,"lang":"en","type":"article","venue":"Pharmacology Biochemistry and Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Agmatine; Corticosterone; Antidepressant; Fluoxetine; Hippocampus; Prefrontal cortex; Ketamine; Endocrinology; Internal medicine; Pharmacology; Hippocampal formation; Tail suspension test; Psychology; Chemistry; Medicine; Behavioural despair test; Serotonin; Neuroscience; Receptor; Biochemistry","score_opus":0.03151842910351823,"score_gpt":0.3160909982693888,"score_spread":0.2845725691658706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886221328","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99895835,0.00020218689,0.0000036217677,0.00027429344,0.00008724784,0.00035950574,0.00004077359,0.000019222472,0.00005477661],"genre_scores_gemma":[0.99939495,0.000026103642,0.000051480965,0.00025773284,0.00003784352,0.00010202257,0.000016282644,0.000010323922,0.00010326907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900687,0.000069121335,0.0002682835,0.00034341484,0.000115670795,0.00019666732],"domain_scores_gemma":[0.9994883,0.00010212308,0.00018954156,0.000109936096,0.000038341823,0.000071762704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006851535,0.0001605061,0.00019458137,0.000029107654,0.00010988476,0.000020712765,0.00013467578,0.00009511502,0.00009148917],"category_scores_gemma":[0.000038668117,0.000120307064,0.000015107935,0.00014609622,0.0007197515,0.00007435115,0.00006530945,0.00017180693,0.0000010630235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002897316,0.0009613807,0.0109726805,0.000034690576,0.0000037562831,0.000016543185,0.00013508304,4.3506e-8,0.98465925,5.7569974e-7,0.0003240924,0.002602198],"study_design_scores_gemma":[0.0016988788,0.00051738066,0.028268952,0.000018284903,0.00012501571,0.00007880473,0.00017522523,0.000020221842,0.9688744,7.227813e-7,0.00008808235,0.00013406243],"about_ca_topic_score_codex":0.000013152149,"about_ca_topic_score_gemma":0.000017651151,"teacher_disagreement_score":0.017296271,"about_ca_system_score_codex":0.000012484492,"about_ca_system_score_gemma":0.000028889615,"threshold_uncertainty_score":0.49059796},"labels":[],"label_agreement":null},{"id":"W2886332567","doi":"10.1101/393173","title":"A new schizophrenia model: immune activation is associated with induction of the tryptophan catabolite pathway and increased eotaxin levels which together determine memory impairments and schizophrenia symptom dimensions","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University; Asahi Glass Foundation","keywords":"Eotaxin; Schizophrenia (object-oriented programming); Xanthurenic acid; Kynurenine; Kynurenine pathway; Psychology; Immunology; Psychosis; Psychiatry; Internal medicine; Immune system; Medicine; Tryptophan; Chemokine; Chemistry; Biochemistry","score_opus":0.017300961982102167,"score_gpt":0.21715078491429943,"score_spread":0.19984982293219727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886332567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973119,0.00020300242,0.00029457352,0.00016895791,0.00028631478,0.0011324405,0.0004115637,0.00018627818,0.000004992411],"genre_scores_gemma":[0.9977283,0.0000602178,0.0016300564,0.00024255329,0.00011961153,0.00007590134,7.3999394e-7,0.00013013619,0.000012512843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99671733,0.000370453,0.00058892404,0.0012119138,0.0006051989,0.00050617993],"domain_scores_gemma":[0.99716866,0.00014472665,0.0008814985,0.001161962,0.00036233113,0.0002808262],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036021898,0.00066124485,0.0006703958,0.0002988232,0.00035628057,0.00018285717,0.00050761807,0.0005319047,0.000022159224],"category_scores_gemma":[0.00082539197,0.0005316875,0.00010061345,0.0010293926,0.00036463572,0.00037757272,0.0006639456,0.0007172039,0.0000030908375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032316294,0.00014467914,0.001016491,0.00008135001,0.00008858405,0.000003519918,0.00011321631,0.000030244977,0.99805015,0.00007704748,0.00003258857,0.000038969858],"study_design_scores_gemma":[0.002696398,0.00009973249,0.16088368,0.0007592117,0.00008071294,1.8494949e-7,0.0000060386847,0.0020733222,0.8327949,0.000043996235,0.00001125194,0.00055054744],"about_ca_topic_score_codex":0.00018984919,"about_ca_topic_score_gemma":0.000022968832,"teacher_disagreement_score":0.16525523,"about_ca_system_score_codex":0.00014675113,"about_ca_system_score_gemma":0.0010382483,"threshold_uncertainty_score":0.9997135},"labels":[],"label_agreement":null},{"id":"W2886676544","doi":"10.1038/s41598-018-30487-6","title":"IL-1β, IL-6, TNF- α and CRP in Elderly Patients with Depression or Alzheimer’s disease: Systematic Review and Meta-Analysis","year":2018,"lang":"en","type":"review","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":583,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Meta-analysis; Depression (economics); Internal medicine; Medicine; Strictly standardized mean difference; Confidence interval; Disease; Tumor necrosis factor alpha; Gastroenterology; Interleukin 6; Alzheimer's disease; Cytokine","score_opus":0.0872503701996251,"score_gpt":0.331693233490763,"score_spread":0.2444428632911379,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886676544","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010670646,0.99449193,0.0000064657015,0.000031257412,0.0003794886,0.0047412184,0.0001195749,0.000051479445,0.00007188737],"genre_scores_gemma":[0.0006221813,0.9954672,0.000062482664,0.00017107907,0.0000119540755,0.00071692705,0.00013566384,0.00006263379,0.002749867],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99312097,0.00080607575,0.0018039752,0.0026194616,0.0011618567,0.0004876692],"domain_scores_gemma":[0.9951154,0.00030673758,0.001933917,0.002117016,0.00014425462,0.00038264677],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017232193,0.0006894166,0.004791373,0.000740799,0.00034675794,0.0005910643,0.0004011427,0.00014486705,0.00025682818],"category_scores_gemma":[0.0015311202,0.00032495795,0.00083823194,0.0029008444,0.00061339664,0.00035172777,0.00026384922,0.0002333029,0.000022723394],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017783193,0.0003780986,0.00016520286,0.97014254,0.012374784,0.0010228098,0.0001016611,7.5744305e-7,8.631425e-7,0.000008941172,0.0042229006,0.011563674],"study_design_scores_gemma":[0.00020342246,0.000089541754,0.000098213226,0.06546814,0.7727698,0.00018709993,0.0000104286455,0.000005737367,0.000008759946,0.00012732661,0.15991047,0.0011210794],"about_ca_topic_score_codex":0.000008966567,"about_ca_topic_score_gemma":0.00006044987,"teacher_disagreement_score":0.9046744,"about_ca_system_score_codex":0.000032225835,"about_ca_system_score_gemma":0.00027032028,"threshold_uncertainty_score":0.99992025},"labels":[],"label_agreement":null},{"id":"W2887186140","doi":"10.1002/jmr.2759","title":"Autoimmunity and immune system dysregulation in schizophrenia: IgGs from sera of patients hydrolyze myelin basic protein","year":2018,"lang":"en","type":"article","venue":"Journal of Molecular Recognition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Registered Nurses’ Foundation of Ontario; Russian Foundation for Basic Research; Rehabilitation Nursing Foundation","keywords":"Autoimmunity; Immune system; Myelin basic protein; Autoantibody; Immunology; Schizophrenia (object-oriented programming); Immune dysregulation; Myelin; Medicine; Antibody; Biology; Neuroscience; Central nervous system; Psychiatry","score_opus":0.012002020515067015,"score_gpt":0.21477944933286588,"score_spread":0.20277742881779887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887186140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99860984,0.0001426699,0.00055765966,0.0000693513,0.00014136243,0.0002747634,0.000021642729,0.000011997062,0.0001707096],"genre_scores_gemma":[0.9992362,0.00001042102,0.00063196156,0.000045375633,0.00004343014,0.0000039286097,0.0000108076465,0.000014743164,0.0000031042434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847406,0.0003527967,0.00057008356,0.0001553617,0.00031983023,0.00012788814],"domain_scores_gemma":[0.99901396,0.00005543303,0.00056685566,0.00013060335,0.000185955,0.00004718055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003008753,0.00011583558,0.00023840304,0.0002453081,0.000059023554,0.000029223438,0.0001292112,0.00008901957,0.000029096105],"category_scores_gemma":[0.00037537975,0.00010888509,0.00007485683,0.00026541683,0.0001079627,0.00028014643,0.00003795856,0.00020983956,0.000010127969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056417246,0.00016476096,0.0002550743,0.000043933946,0.0000099979725,0.000014472203,0.00018576288,0.000005352916,0.9614749,0.000038428447,0.0000022567165,0.037240874],"study_design_scores_gemma":[0.0029902859,0.00038532246,0.07196132,0.000521767,0.000016045295,0.000013064624,0.00009092622,0.0005411898,0.9205784,0.002779254,0.000009513682,0.00011288991],"about_ca_topic_score_codex":0.000044438555,"about_ca_topic_score_gemma":0.000008078715,"teacher_disagreement_score":0.07170625,"about_ca_system_score_codex":0.00004974959,"about_ca_system_score_gemma":0.0000412226,"threshold_uncertainty_score":0.4440205},"labels":[],"label_agreement":null},{"id":"W2887410835","doi":"10.1093/cid/ciy676","title":"Plasma Indoleamine 2,3-Dioxygenase Activity Is Associated With the Size of the Human Immunodeficiency Virus Reservoir in Patients Receiving Antiretroviral Therapy","year":2018,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Natural Science Foundation of China","keywords":"Indoleamine 2,3-dioxygenase; Peripheral blood mononuclear cell; Medicine; Immunology; Odds ratio; Kynurenine; Viral load; CD8; Flow cytometry; Confidence interval; Virus; Virology; Internal medicine; Immune system; Biology; Tryptophan","score_opus":0.037404978088596046,"score_gpt":0.31843261340037443,"score_spread":0.2810276353117784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887410835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998146,0.0000244274,0.0000012804389,0.00016614466,0.0002459754,0.0005035952,0.000074355085,0.00007607744,0.0007621615],"genre_scores_gemma":[0.998569,0.00003482431,3.4995207e-7,0.001168184,0.00007237179,0.000019592939,0.0000016024331,0.000026424112,0.00010765835],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99726814,0.00099271,0.00044491774,0.00048669797,0.00044056,0.00036700213],"domain_scores_gemma":[0.99640673,0.002315358,0.00044931594,0.0006380298,0.00011542621,0.00007514824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039088546,0.00021827758,0.00034433967,0.00005494913,0.00049825985,0.000060928793,0.0006006593,0.0001177318,0.000080478174],"category_scores_gemma":[0.006558319,0.00011999167,0.00022321836,0.000916041,0.0014889176,0.00019397229,0.00019200644,0.00040590196,0.0000112036505],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031124224,0.003797483,0.9762489,0.000007774414,0.00002751838,0.000002301842,0.00025008165,0.000008486415,0.014645415,0.00002460934,0.0006056387,0.0040705553],"study_design_scores_gemma":[0.0032008768,0.0016975576,0.96098304,0.00005706715,0.000008324764,2.3487269e-7,0.000024754738,0.000058894675,0.033570316,0.00016875112,0.00006582276,0.00016433932],"about_ca_topic_score_codex":0.00012484082,"about_ca_topic_score_gemma":0.00030137246,"teacher_disagreement_score":0.018924901,"about_ca_system_score_codex":0.000056208308,"about_ca_system_score_gemma":0.000106601634,"threshold_uncertainty_score":0.7851394},"labels":[],"label_agreement":null},{"id":"W2887725539","doi":"10.1016/j.jpsychires.2018.08.011","title":"Genetic disposition to inflammation and response to antidepressants in major depressive disorder","year":2018,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Nova Scotia Health Authority; Dalhousie University","funders":"H. Lundbeck A/S; Canada Research Chairs; Canadian Institutes of Health Research; National Institute for Health and Care Research; King's College London; Nova Scotia Health Research Foundation; European Commission; Dalhousie Medical Research Foundation; Dalhousie University; GlaxoSmithKline","keywords":"Major depressive disorder; Inflammation; Disposition; Medicine; Psychiatry; Psychology; Clinical psychology; Internal medicine; Cognition","score_opus":0.03223018541310442,"score_gpt":0.3649396608245781,"score_spread":0.3327094754114737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887725539","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99241316,0.00019992216,0.0010833178,0.005368101,0.00021815422,0.00040710965,0.000003206639,0.000006097746,0.00030090185],"genre_scores_gemma":[0.9976027,0.00009901837,0.0016753025,0.00017504726,0.00032808413,0.000010593361,8.410503e-8,0.000014904837,0.000094276365],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99736273,0.0007977203,0.0004207244,0.0002749228,0.00077363424,0.0003702675],"domain_scores_gemma":[0.99871856,0.00049446867,0.00011336608,0.00019981318,0.00023095774,0.00024281621],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013498733,0.00009722974,0.00015327016,0.0014747535,0.00019697117,0.000119881704,0.00035307207,0.000059295184,0.00004459767],"category_scores_gemma":[0.0023797161,0.000081525606,0.000037712834,0.0017088613,0.00010732831,0.00019704981,0.00012676248,0.00030831588,0.00007088595],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0087162,0.00021299298,0.07154698,0.000039919763,0.000007518844,0.00010788372,0.0028920444,0.00014620867,0.8681009,0.00021244984,0.00501767,0.042999256],"study_design_scores_gemma":[0.001960506,0.0015030048,0.95231277,0.00007494388,0.0000041435187,0.00007478805,0.0002724928,0.00013875111,0.03942153,0.0024687848,0.0016257092,0.00014256324],"about_ca_topic_score_codex":0.00003708326,"about_ca_topic_score_gemma":0.00010451755,"teacher_disagreement_score":0.8807658,"about_ca_system_score_codex":0.0000544197,"about_ca_system_score_gemma":0.000118368334,"threshold_uncertainty_score":0.33245176},"labels":[],"label_agreement":null},{"id":"W2888219336","doi":"10.1016/j.pnpbp.2018.08.013","title":"Increased thioredoxin-interacting protein in brain of mice exposed to chronic stress","year":2018,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Thioredoxin; Oxidative stress; Cell biology; Signal transduction; Protein kinase A; Kinase; Nitrosylation; Phosphorylation; TXNIP; Biology; Chemistry; Biochemistry; Endocrinology; Nitric oxide","score_opus":0.02659458911596019,"score_gpt":0.32972045298048547,"score_spread":0.3031258638645253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888219336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911207,0.0005108322,0.0000073622737,0.0054055625,0.0011627737,0.0012139303,0.000021874748,0.000078211175,0.00047876607],"genre_scores_gemma":[0.99312145,0.000049401922,0.00049593294,0.005835765,0.00027231648,0.00018983995,0.0000023546888,0.000019727053,0.000013215952],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9968921,0.0007175915,0.00061111787,0.0009777896,0.00016314292,0.000638272],"domain_scores_gemma":[0.9987291,0.0006449282,0.00021480472,0.00021439274,0.000031573883,0.00016519305],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039674915,0.0003072727,0.00040278732,0.0003393553,0.000106117564,0.000027832284,0.00060286047,0.0002524251,0.00017795635],"category_scores_gemma":[0.00055650255,0.00024901074,0.000071575705,0.00082507235,0.0008240306,0.00011906663,0.00021637688,0.00059294293,0.000021509344],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003357095,0.0012063528,0.4760304,0.00009816774,0.000007975341,0.000049017734,0.00024145991,0.000002408502,0.5053167,0.0007760551,0.0004009666,0.0125134],"study_design_scores_gemma":[0.008439594,0.003617202,0.87054425,0.00032410174,0.000007003764,0.00003704357,0.00019033588,0.000339644,0.11262354,0.0018925521,0.0013757178,0.0006089943],"about_ca_topic_score_codex":0.0000074812892,"about_ca_topic_score_gemma":0.00010088328,"teacher_disagreement_score":0.39451385,"about_ca_system_score_codex":0.00002795482,"about_ca_system_score_gemma":0.00007142291,"threshold_uncertainty_score":0.9999962},"labels":[],"label_agreement":null},{"id":"W2890191325","doi":"10.2174/1568026618666181115093136","title":"Anxiety Disorders: Sex Differences in Serotonin and Tryptophan Metabolism","year":2018,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Serotonin transporter; Anxiety; Serotonin; Anxiogenic; Kynurenine; Serotonin Plasma Membrane Transport Proteins; Medicine; Endocrinology; Internal medicine; Psychology; Tryptophan; Biology; Psychiatry; Receptor; Anxiolytic; Genetics","score_opus":0.06359803012698073,"score_gpt":0.3413592930979954,"score_spread":0.27776126297101467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890191325","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011265078,0.9854907,0.0000048193124,0.00006975647,0.00066233915,0.0005638326,0.000026449005,0.000043725173,0.0018733462],"genre_scores_gemma":[0.0018225837,0.9968935,0.000019148458,0.000045632645,0.0007030527,0.00015933474,0.000024073632,0.00003325118,0.00029937873],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997035,0.00018743823,0.00073518197,0.0010464848,0.00044543296,0.00055044336],"domain_scores_gemma":[0.998902,0.00021936215,0.00025295658,0.00043921484,0.000012747959,0.00017371456],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027333782,0.0005871156,0.0014119655,0.00015150366,0.00006885718,0.00005613906,0.0007200082,0.00040051903,0.00015093948],"category_scores_gemma":[0.00056364207,0.0004756033,0.00017909387,0.00056343054,0.0005373363,0.00008632463,0.0002425752,0.0012589133,0.000008664818],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005354868,0.00016171637,0.0004122264,0.013161513,0.000006114126,0.00001138499,0.0002963477,1.7935411e-8,0.000028949,0.000108193606,0.00018686148,0.98562133],"study_design_scores_gemma":[0.00067308184,0.000018726447,0.00021370132,0.008026943,0.000048631344,0.000031164094,0.00011271521,0.000021071239,0.00043700373,0.0009444528,0.9889279,0.000544601],"about_ca_topic_score_codex":0.00001058838,"about_ca_topic_score_gemma":0.00001824777,"teacher_disagreement_score":0.98874104,"about_ca_system_score_codex":0.00008772711,"about_ca_system_score_gemma":0.000196566,"threshold_uncertainty_score":0.99976957},"labels":[],"label_agreement":null},{"id":"W2890430536","doi":"10.1016/j.neuron.2018.08.031","title":"Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation","year":2018,"lang":"en","type":"article","venue":"Neuron","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":245,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa","funders":"Fundamental Research Funds for the Central Universities; National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"MEN1; Neuroinflammation; Astrocyte; Inflammation; Downregulation and upregulation; Pathogenesis; Major depressive disorder; Neuroscience; Endocrinology; Psychology; Internal medicine; Medicine; Biology; Central nervous system; Endocrine system; Gene; Genetics; Hormone","score_opus":0.01620779017216161,"score_gpt":0.25999743781337803,"score_spread":0.2437896476412164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890430536","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972989,0.000012215769,0.00026045606,0.00029304382,0.00035561417,0.00035792447,0.000012746927,0.00014717312,0.0012619497],"genre_scores_gemma":[0.99849266,0.0000048060815,0.00011081352,0.0010853395,0.000049454145,0.000026484076,0.000006701458,0.000034471566,0.00018929444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980664,0.00016315837,0.00031011863,0.0006379817,0.00034922428,0.0004730971],"domain_scores_gemma":[0.9993496,0.00015820679,0.00010861279,0.00023235436,0.000028909963,0.00012230489],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000086969434,0.00019536768,0.00014467616,0.00018746307,0.00015541755,0.00006932399,0.00035105748,0.00006818689,0.000050383947],"category_scores_gemma":[0.0006561435,0.00020592003,0.00003862362,0.00066208234,0.000100762336,0.00027667198,0.000108845816,0.00020726954,0.00026918502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038797134,0.000070246344,0.0021880139,0.0000050486074,1.4901583e-7,0.0000128595675,0.00031268553,0.00018518462,0.99390614,0.000022991107,0.00082228426,0.0024355717],"study_design_scores_gemma":[0.0007592619,0.0003935544,0.038815618,0.000021430455,0.0000035936173,0.000009549845,0.000036261925,0.0041474923,0.9545917,0.000018673561,0.00093893474,0.00026393874],"about_ca_topic_score_codex":0.00004509788,"about_ca_topic_score_gemma":0.00007359963,"teacher_disagreement_score":0.03931448,"about_ca_system_score_codex":0.000038562433,"about_ca_system_score_gemma":0.00002620886,"threshold_uncertainty_score":0.8397175},"labels":[],"label_agreement":null},{"id":"W2890450469","doi":"10.1038/s41380-018-0247-6","title":"Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples","year":2018,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Alcohol Abuse and Alcoholism; National Institute of Mental Health; Medical Research Council; Universitair Medisch Centrum Groningen; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Vrije Universiteit Amsterdam; National Institutes of Health; U.S. Department of Health and Human Services; Universiteit Leiden; Leids Universitair Medisch Centrum","keywords":"Replicate; Major depressive disorder; Psychology; Association (psychology); Neuroscience; DNA methylation; Schizophrenia (object-oriented programming); Psychiatry; Biology; Genetics; Cognition; Gene; Psychotherapist","score_opus":0.009993961100829224,"score_gpt":0.2616791080799637,"score_spread":0.25168514697913447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890450469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9822297,0.0005358873,0.0011828273,0.014952162,0.00017414284,0.0006650449,0.000032323678,0.00003588769,0.00019201443],"genre_scores_gemma":[0.9891881,0.000036211855,0.0011831498,0.009256968,0.00003703514,0.0001059876,0.0000065311137,0.000036553036,0.00014948077],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9980657,0.00018765635,0.00032105204,0.00076156773,0.00023985896,0.00042414336],"domain_scores_gemma":[0.99872774,0.0007654128,0.00014181467,0.00026148293,0.00002311104,0.00008046276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004809784,0.00020608536,0.0002375426,0.00025109388,0.00012299248,0.00009289453,0.00018564778,0.00015566175,0.000012103187],"category_scores_gemma":[0.0029854544,0.0002156636,0.000058485264,0.00037740255,0.000101941616,0.00014411098,0.000110969144,0.00020143381,0.0000035612818],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011745069,0.00024671783,0.76375645,0.0000706814,0.000021859943,0.000010929946,0.0006004718,0.000004311946,0.22796683,0.0047472185,0.0013953133,0.0010617648],"study_design_scores_gemma":[0.008721329,0.0003344622,0.8307174,0.00009642897,0.000029159508,0.000014757134,0.00037634888,0.00013017752,0.108692035,0.048061837,0.0022396946,0.0005863786],"about_ca_topic_score_codex":0.00013226621,"about_ca_topic_score_gemma":0.0012960655,"teacher_disagreement_score":0.119274795,"about_ca_system_score_codex":0.000038754144,"about_ca_system_score_gemma":0.00005093219,"threshold_uncertainty_score":0.8794506},"labels":[],"label_agreement":null},{"id":"W2890592361","doi":"10.1186/s40608-018-0208-2","title":"Obesity moderates the complex relationships between inflammation, oxidative stress, sleep quality and depressive symptoms","year":2018,"lang":"en","type":"article","venue":"BMC Obesity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Women's College Hospital; University of Toronto","funders":"","keywords":"Medicine; Body mass index; National Health and Nutrition Examination Survey; Obesity; Confounding; Internal medicine; Depression (economics); Oxidative stress; Odds ratio; Population; Environmental health","score_opus":0.09825093712502746,"score_gpt":0.3116314075730562,"score_spread":0.21338047044802871,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890592361","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9838601,0.000029133815,0.013218835,0.00048100026,0.00006318635,0.0004475554,0.00009920796,0.00012759837,0.0016733824],"genre_scores_gemma":[0.99919516,0.000005880245,0.00021481115,0.00014494745,0.00028661176,0.000016319973,0.0000210733,0.000012583721,0.000102629994],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9975201,0.0010688837,0.0003157204,0.00048118483,0.0003106589,0.00030348415],"domain_scores_gemma":[0.99751514,0.0015758862,0.00022785603,0.000440932,0.00012204735,0.00011812622],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0004085034,0.00019519193,0.00021495027,0.00004850321,0.0013986995,0.00015447542,0.00035673342,0.00010989387,0.00008521023],"category_scores_gemma":[0.0019219578,0.0001476745,0.000053989075,0.0002714702,0.00079747126,0.0003978093,0.00021628111,0.0002728457,0.00008228036],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024012006,0.00005419293,0.9725234,0.000024122244,0.000012397261,5.8596135e-7,0.0012843237,0.00006836981,0.007557056,0.017769376,0.0002917312,0.00039045102],"study_design_scores_gemma":[0.0003554072,0.000029478519,0.8939928,0.000012331071,0.000014241183,0.0000012274368,0.00016651332,0.0018089421,0.0892859,0.013999595,0.00015398077,0.0001796162],"about_ca_topic_score_codex":0.0001286437,"about_ca_topic_score_gemma":0.0007941079,"teacher_disagreement_score":0.081728846,"about_ca_system_score_codex":0.0000359401,"about_ca_system_score_gemma":0.000050850034,"threshold_uncertainty_score":0.99990135},"labels":[],"label_agreement":null},{"id":"W2891018058","doi":"10.1177/0004867418796955","title":"Leaky brain in neurological and psychiatric disorders: Drivers and consequences","year":2018,"lang":"en","type":"review","venue":"Australian & New Zealand Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":139,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Psychiatry; Psychology; Medicine","score_opus":0.04378818707278094,"score_gpt":0.32291898869051744,"score_spread":0.2791308016177365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891018058","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013261322,0.9621559,0.0000028255672,0.021619445,0.0022182588,0.00048618764,0.00002760928,0.000027134267,0.00020133417],"genre_scores_gemma":[0.0006902817,0.99584013,0.00058953295,0.0008229519,0.0006687968,0.0000026788318,0.0000017236825,0.000039993833,0.0013438952],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99685645,0.000492716,0.001119023,0.000655786,0.00034368754,0.0005323095],"domain_scores_gemma":[0.9978304,0.00048414627,0.0010032029,0.0002362441,0.00001880613,0.0004272208],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038595044,0.0005408465,0.0013087667,0.00066650705,0.000119802964,0.00016087905,0.0005684095,0.00044531145,0.000106878935],"category_scores_gemma":[0.00030668234,0.0003944536,0.00035628292,0.000675392,0.000718744,0.0002708168,0.000076823424,0.0011053059,0.000017874925],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002393145,0.0005478305,0.02588439,0.003599372,0.00011806345,0.00023502037,0.00037025704,0.0000017099799,0.000013240306,0.0020146426,0.3827887,0.58418745],"study_design_scores_gemma":[0.001407913,0.0012742222,0.0029295825,0.0022102257,0.00016411043,0.0017198466,0.000070094815,6.1471667e-7,8.319756e-7,0.010984718,0.9787572,0.00048064697],"about_ca_topic_score_codex":0.000041573454,"about_ca_topic_score_gemma":0.00027693924,"teacher_disagreement_score":0.5959685,"about_ca_system_score_codex":0.00001512521,"about_ca_system_score_gemma":0.0005816619,"threshold_uncertainty_score":0.99985075},"labels":[],"label_agreement":null},{"id":"W2891750344","doi":"10.1016/j.schres.2018.09.008","title":"An Interleukin-1 beta (IL1B) haplotype linked with psychosis transition is associated with IL1B gene expression and brain structure","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; Alberta Children's Hospital; University of Calgary","funders":"National Health and Medical Research Council; Ramsay Health Care; University of New South Wales; Schizophrenia Research Institute; Pratt Foundation; Sylvia and Charles Viertel Charitable Foundation; Australian Government; Brain and Behavior Research Foundation","keywords":"Psychosis; Dorsolateral prefrontal cortex; Haplotype; Prefrontal cortex; Schizophrenia (object-oriented programming); Gene expression; Grey matter; Biology; Psychology; Human brain; Neuroscience; Internal medicine; Gene; Endocrinology; Genetics; Medicine; Psychiatry; Genotype; Magnetic resonance imaging; White matter; Cognition","score_opus":0.040469397395498374,"score_gpt":0.3259367574515722,"score_spread":0.2854673600560738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891750344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956261,0.000046486286,0.00024048962,0.0029766192,0.00006549927,0.0005259507,0.00012296173,0.00015049023,0.000245423],"genre_scores_gemma":[0.997186,0.00002338659,0.0013509408,0.0009269419,0.00018912816,0.000028276138,0.000032734104,0.00006947084,0.00019313766],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963946,0.00065601117,0.00021013764,0.000991757,0.0010586488,0.00068888685],"domain_scores_gemma":[0.99849397,0.00026477975,0.000075012635,0.0006007684,0.0002633848,0.00030210914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000463724,0.0002758752,0.0002539539,0.00035846603,0.0006731363,0.00029848958,0.00051127817,0.00021491277,0.0003546724],"category_scores_gemma":[0.00019932602,0.00019593636,0.00003540687,0.0010795523,0.0010520457,0.00046527397,0.00007621026,0.00073231093,0.00003347032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042789876,0.00015900489,0.00046129915,0.000018709705,0.0000194695,0.000027983539,0.0025425102,0.0000026620837,0.9859989,0.00016540433,0.0016666845,0.004658367],"study_design_scores_gemma":[0.005496604,0.0042886697,0.020787222,0.0002652308,0.000012784759,0.0000434927,0.0003835455,0.00076446123,0.96503323,0.0020004192,0.00044107245,0.000483266],"about_ca_topic_score_codex":0.000053076004,"about_ca_topic_score_gemma":0.00057552906,"teacher_disagreement_score":0.020965686,"about_ca_system_score_codex":0.00005783762,"about_ca_system_score_gemma":0.00012460467,"threshold_uncertainty_score":0.79900527},"labels":[],"label_agreement":null},{"id":"W2891816107","doi":"10.1093/ijnp/pyw041.524","title":"PM524. VEGF may have a neuroprotective role in the improvement of schizophrenia or in the treatment effects of antipsychotics","year":2016,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia (object-oriented programming); Neuroprotection; Medicine; VEGF receptors; Neuroscience; Psychology; Psychiatry; Pharmacology; Internal medicine","score_opus":0.021215303815516447,"score_gpt":0.3188765337268512,"score_spread":0.29766122991133476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891816107","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890977,0.00008213101,0.0000363472,0.008863238,0.0011525309,0.00057506416,0.000010825415,0.000003338793,0.00017879365],"genre_scores_gemma":[0.99570686,0.000936357,0.000014696812,0.0030945234,0.00016507877,0.000027520931,9.363878e-8,0.000013166486,0.00004172941],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99767613,0.0008003748,0.00058095885,0.00019169976,0.0005502928,0.00020056813],"domain_scores_gemma":[0.99658066,0.002500117,0.0005781064,0.0002137389,0.00010042567,0.00002695706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044929254,0.00016181602,0.00022988018,0.0002419071,0.00003534984,0.000019916093,0.001594297,0.000036301146,0.000038616716],"category_scores_gemma":[0.00035910544,0.00006145064,0.00014386543,0.00026139905,0.00026769657,0.00009612371,0.000047307374,0.0002941714,0.0000045153324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00644499,0.0012192886,0.0002648099,0.0000075560692,0.000042738753,0.00034137382,0.0018492711,0.000049191312,0.96279585,0.00025830753,0.0001799888,0.026546638],"study_design_scores_gemma":[0.020990279,0.007751944,0.10154965,0.00016991043,0.000065238346,0.0007467013,0.0008034692,0.00014606153,0.8604457,0.003583301,0.0035571577,0.00019061171],"about_ca_topic_score_codex":0.00001648957,"about_ca_topic_score_gemma":0.000024796693,"teacher_disagreement_score":0.10235017,"about_ca_system_score_codex":0.000052489875,"about_ca_system_score_gemma":0.00007746821,"threshold_uncertainty_score":0.2962627},"labels":[],"label_agreement":null},{"id":"W2892238272","doi":"10.1007/s12035-019-01737-z","title":"The Role of Aberrations in the Immune-Inflammatory Response System (IRS) and the Compensatory Immune-Regulatory Reflex System (CIRS) in Different Phenotypes of Schizophrenia: the IRS-CIRS Theory of Schizophrenia","year":2019,"lang":"en","type":"review","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":167,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Asahi Glass Foundation","keywords":"Immunology; Immune system; Tumor necrosis factor alpha; Inflammation; Medicine","score_opus":0.015847981925620244,"score_gpt":0.2543965916222536,"score_spread":0.23854860969663333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2892238272","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.26337138,0.7320886,0.000007982915,0.00013137526,0.000518537,0.0032808231,0.00008138894,0.000039950162,0.00047992068],"genre_scores_gemma":[0.90363383,0.09587418,0.0000035236894,0.000059782822,0.00003054257,0.00028302398,0.000008643212,0.00008029411,0.00002617817],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9774977,0.018523706,0.002201619,0.0007908169,0.00043249573,0.00055365666],"domain_scores_gemma":[0.98612094,0.009515185,0.0017966673,0.0024476764,0.00007814987,0.000041398034],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0038199008,0.0007233217,0.0023067994,0.00038497985,0.00031801447,0.000050090006,0.0026520048,0.0004356711,0.0000034295147],"category_scores_gemma":[0.0009605692,0.00032638712,0.00079590234,0.0006799868,0.002921059,0.000057059988,0.00059801905,0.0011780547,0.0000104669725],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00854363,0.00031960427,0.00003327819,0.011790615,0.00042042462,0.000066601046,0.002458275,0.0001646,0.16635357,0.7760305,0.000026699745,0.033792216],"study_design_scores_gemma":[0.09251031,0.007243707,0.08267881,0.123889625,0.010641861,0.005785436,0.082867704,0.0034077582,0.25420982,0.022013918,0.30002335,0.014727698],"about_ca_topic_score_codex":0.000033184308,"about_ca_topic_score_gemma":0.00003587654,"teacher_disagreement_score":0.7540166,"about_ca_system_score_codex":0.0001097154,"about_ca_system_score_gemma":0.0004418556,"threshold_uncertainty_score":0.9999188},"labels":[],"label_agreement":null},{"id":"W2893975246","doi":"10.3389/fphar.2018.01149","title":"Changes in Membrane Protein Clustering in Peripheral Lymphocytes in an Animal Model of Depression Parallel Those Observed in Naïve Depression Patients: Implications for the Development of Novel Biomarkers of Depression","year":2018,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; University of Calgary; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Serotonin; 5-HT2A receptor; Depression (economics); Serotonin transporter; Internal medicine; Serotonin Plasma Membrane Transport Proteins; 5-HT receptor; Receptor; Corticosterone; Endocrinology; Major depressive disorder; Psychology; Biomarker; Lipid raft; Biology; Medicine; Biochemistry","score_opus":0.07173660253828494,"score_gpt":0.3282939445230535,"score_spread":0.25655734198476854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2893975246","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99147767,0.00019465598,0.0061858348,0.000087922424,0.0001869405,0.0018037799,0.000029208688,0.000009445768,0.000024515579],"genre_scores_gemma":[0.9781173,0.00007193628,0.020930314,0.00008369953,0.000009912729,0.0007528198,0.000008959518,0.000021338012,0.0000037387697],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99801004,0.0002303042,0.0007281694,0.0004887478,0.00015282366,0.00038990378],"domain_scores_gemma":[0.99923074,0.00015669364,0.00031262037,0.00020305946,0.00005251398,0.000044386707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004211543,0.00019125546,0.00038009847,0.0005268614,0.00005287013,0.0000053389945,0.0005136057,0.00016153698,0.0000073432543],"category_scores_gemma":[0.00016373058,0.0001613748,0.000036562265,0.0005837731,0.00024068242,0.00022696369,0.00022050382,0.00014125786,5.7886925e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025892763,0.00085220893,0.2598376,0.000098694545,0.0000045968113,4.3940165e-7,0.0028197663,0.008695202,0.71505123,0.000002688174,0.000020356021,0.010027922],"study_design_scores_gemma":[0.006575934,0.0000950692,0.28413796,0.0001840201,0.000003197022,2.4092475e-7,0.00036707643,0.2076414,0.5008141,0.00005478776,0.0000061207543,0.00012010051],"about_ca_topic_score_codex":0.000114094466,"about_ca_topic_score_gemma":0.0029915283,"teacher_disagreement_score":0.21423717,"about_ca_system_score_codex":0.00019914152,"about_ca_system_score_gemma":0.00015899404,"threshold_uncertainty_score":0.65806735},"labels":[],"label_agreement":null},{"id":"W2894410744","doi":"10.1002/acn3.637","title":"Altered tryptophan metabolism is associated with pediatric multiple sclerosis risk and course","year":2018,"lang":"en","type":"article","venue":"Annals of Clinical and Translational Neurology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; Race to Erase MS; National Multiple Sclerosis Society","keywords":"Medicine; Kynurenine; Metabolite; Internal medicine; Odds ratio; Hazard ratio; Proportional hazards model; Gut flora; Physiology; Microbiome; Tryptophan; Metabolomics; Confidence interval; Bioinformatics; Immunology; Biology; Genetics; Amino acid","score_opus":0.14919575253166364,"score_gpt":0.35449844937508945,"score_spread":0.2053026968434258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2894410744","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99325424,0.0002580982,0.000097900156,0.0057022246,0.00015264597,0.00013774101,0.00018317082,0.000027534406,0.00018642054],"genre_scores_gemma":[0.9910685,0.0015889675,0.000068891575,0.006997059,0.00023776194,0.000004096992,0.00000411861,0.000013147595,0.000017491457],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982089,0.0003803987,0.00048914575,0.00047180723,0.00021523495,0.00023450814],"domain_scores_gemma":[0.9971064,0.002278418,0.00024514564,0.00012270297,0.0001035603,0.0001438028],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003538797,0.00014484333,0.00037517335,0.000065827226,0.00014059995,0.000014646435,0.00011380604,0.0001567041,0.00006902305],"category_scores_gemma":[0.00081646314,0.00011435747,0.00009291493,0.00021362018,0.0010061085,0.000119756805,0.000022785944,0.00024754007,0.0000061637656],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019469558,0.00074028695,0.97393864,0.000014852585,0.000071978066,0.000007335011,0.00034473115,0.0000070457245,0.00088214414,0.0017594073,0.00069729553,0.01958935],"study_design_scores_gemma":[0.002618802,0.00064175605,0.9874886,0.0000037550499,0.00004072591,0.0000048702977,0.00000265738,0.0007123069,0.0021508995,0.0054026446,0.00081354025,0.00011941838],"about_ca_topic_score_codex":0.000013603173,"about_ca_topic_score_gemma":0.000048233655,"teacher_disagreement_score":0.019469932,"about_ca_system_score_codex":5.7837894e-8,"about_ca_system_score_gemma":0.00004634615,"threshold_uncertainty_score":0.46633622},"labels":[],"label_agreement":null},{"id":"W2895301659","doi":"10.20944/preprints201810.0083.v2","title":"In Schizophrenia, Low Natural IgM Antibody Titers to Oxidative Specific Epitopes and Higher IgM Responses to Nitrated and Nitrosylated Proteins Strongly Predict Negative Symptoms, Neurocognitive Impairments and the Deficit Syndrome","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University; Asahi Glass Foundation","keywords":"Antibody; Immunology; Schizophrenia (object-oriented programming); Autoantibody; Internal medicine; Chemistry; Medicine; Psychiatry","score_opus":0.03824197531365304,"score_gpt":0.3090486069677208,"score_spread":0.27080663165406776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2895301659","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913798,0.00015025535,0.000020613745,0.0011883716,0.0004550051,0.005984289,0.00035749335,0.00016166504,0.00030253688],"genre_scores_gemma":[0.9977585,0.00015956625,0.00015088433,0.00084924366,0.000076132004,0.00052195904,0.000024415147,0.00007480101,0.00038449085],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99426264,0.0013821194,0.00068785297,0.0023433405,0.0005562554,0.0007677866],"domain_scores_gemma":[0.9974487,0.0008865889,0.0003472212,0.00077270914,0.00018105602,0.0003637624],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006517343,0.0008254756,0.000845539,0.00062628597,0.00030876568,0.00028293312,0.00071979995,0.00030174083,0.0001290445],"category_scores_gemma":[0.0015800704,0.0006669431,0.00010124986,0.0007504864,0.001281373,0.00041369683,0.002676786,0.0013166211,0.00015926831],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.034719594,0.00090775365,0.21881224,0.0005325049,0.0004549203,0.0007641152,0.017628718,0.00010851839,0.72403467,0.0004849221,0.000111662695,0.0014403847],"study_design_scores_gemma":[0.0046986076,0.0003890003,0.9010623,0.0007401973,0.000041038867,0.00009812087,0.00032144267,0.00011866066,0.09019805,0.0014818652,0.00008317198,0.00076754024],"about_ca_topic_score_codex":0.00028238675,"about_ca_topic_score_gemma":0.0000476246,"teacher_disagreement_score":0.6822501,"about_ca_system_score_codex":0.00011861956,"about_ca_system_score_gemma":0.0001478919,"threshold_uncertainty_score":0.9995782},"labels":[],"label_agreement":null},{"id":"W2896066839","doi":"10.1038/s41398-018-0256-x","title":"Effects of tumor necrosis factor-α polymorphism on the brain structural changes of the patients with major depressive disorder","year":2018,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"School of Medicine, Shanghai Jiao Tong University; Robarts Research Institute; Shandong University; Shanghai Jiao Tong University; National Natural Science Foundation of China; Lawson Health Research Institute","keywords":"Major depressive disorder; Tumor necrosis factor α; Medicine; Tumor necrosis factor alpha; Depressive symptoms; Polymorphism (computer science); Schizophrenia (object-oriented programming); Internal medicine; Psychiatry; Psychology; Genotype; Genetics; Cognition; Amygdala; Gene; Biology","score_opus":0.009173259813204462,"score_gpt":0.22820129401792913,"score_spread":0.21902803420472466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896066839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911017,0.000059404545,0.000042125575,0.0074099745,0.00041210634,0.00054466305,0.00014220543,0.000015099567,0.00027271832],"genre_scores_gemma":[0.9977929,7.3219314e-7,0.00006929024,0.0019943553,0.000065568056,0.000013696604,0.0000027561741,0.000017561195,0.0000431414],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988728,0.00011557558,0.00015474431,0.00023494779,0.00045333576,0.00016857054],"domain_scores_gemma":[0.99906635,0.00045800064,0.00017147364,0.00023053441,0.000043880133,0.00002974409],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000026926102,0.00015343112,0.00012689196,0.00004738895,0.00020993006,0.000011183239,0.00034420425,0.000037668502,0.0001375133],"category_scores_gemma":[0.000068217865,0.00007700955,0.00008115801,0.00027699926,0.00047564227,0.00006454828,0.00001703575,0.00011367538,0.0000043751],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019603863,0.00093237316,0.77648354,0.00035899016,0.00013455599,5.547783e-7,0.0044971406,0.00006652145,0.14367954,0.065528974,0.0017377966,0.004619635],"study_design_scores_gemma":[0.0016962161,0.00022508115,0.91756624,0.00006675776,0.000013329544,5.5112076e-7,0.000019568784,0.000035329955,0.0762378,0.003978669,0.000052263407,0.00010820605],"about_ca_topic_score_codex":0.000024853554,"about_ca_topic_score_gemma":0.00014834137,"teacher_disagreement_score":0.1410827,"about_ca_system_score_codex":0.0000039702595,"about_ca_system_score_gemma":0.000051242958,"threshold_uncertainty_score":0.31403583},"labels":[],"label_agreement":null},{"id":"W2896536443","doi":"10.1159/000492030","title":"IL-18 Serum Levels and Variants of the Serotonin Transporter Gene Are Related to Awareness of Emotions in Healthy Subjects: A Preliminary Study","year":2018,"lang":"en","type":"article","venue":"NeuroImmunoModulation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Serotonin transporter; Serotonin; Psychology; Gene; Depression (economics); Transporter; Medicine; Internal medicine; Endocrinology; Genetics; Biology; Receptor","score_opus":0.0511617399971547,"score_gpt":0.29975146134925723,"score_spread":0.24858972135210253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896536443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978546,0.000010106502,0.000113991446,0.00047669644,0.00022347014,0.001177344,0.000070169015,0.000023610113,0.000050013186],"genre_scores_gemma":[0.9997088,0.0000027448,0.00002617046,0.00017603522,0.0000074021327,0.000018527686,0.0000012098184,0.000018468156,0.00004067865],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99854916,0.00029038324,0.00039728917,0.00036755,0.0002179882,0.0001776157],"domain_scores_gemma":[0.99917644,0.00007695641,0.00024951212,0.00040672865,0.000057587808,0.00003278046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001754754,0.0001275339,0.00019919939,0.00016089428,0.00013021329,0.000011578881,0.00021155922,0.000050299397,0.00002664286],"category_scores_gemma":[0.00016232756,0.000108490516,0.000036720772,0.00079487177,0.000114253475,0.00015994873,0.00005788309,0.00011790339,0.0000026575094],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008373358,0.00095889304,0.35865417,0.00006972187,0.000009393363,0.000009631268,0.007751081,0.0015233376,0.6270178,0.00007713027,0.000008736589,0.0030828072],"study_design_scores_gemma":[0.0011511373,0.001095137,0.9620663,0.000053715707,0.00000678507,0.000009343594,0.00022098649,0.0011147808,0.0340505,0.00013817487,0.0000064870187,0.0000866861],"about_ca_topic_score_codex":0.00008070163,"about_ca_topic_score_gemma":0.00012466672,"teacher_disagreement_score":0.6034121,"about_ca_system_score_codex":0.000018597559,"about_ca_system_score_gemma":0.000056483143,"threshold_uncertainty_score":0.44241148},"labels":[],"label_agreement":null},{"id":"W2897267201","doi":"10.1007/s12640-018-9987-y","title":"In Schizophrenia, Increased Plasma IgM/IgA Responses to Gut Commensal Bacteria Are Associated with Negative Symptoms, Neurocognitive Impairments, and the Deficit Phenotype","year":2018,"lang":"en","type":"article","venue":"Neurotoxicity Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Chulalongkorn University; Asahi Glass Foundation","keywords":"Morganella morganii; Immunology; Immune system; Positive and Negative Syndrome Scale; Antibody; Schizophrenia (object-oriented programming); Biology; Klebsiella pneumoniae; Psychosis; Medicine; Psychiatry","score_opus":0.04962602771950573,"score_gpt":0.3280176812033564,"score_spread":0.27839165348385064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897267201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925945,0.0000051000875,0.000003749124,0.0030494148,0.00007752457,0.0029580416,0.00015244618,0.00008904968,0.0010702156],"genre_scores_gemma":[0.9943648,0.0000101968635,0.000029092991,0.0048499787,0.0000829799,0.00037039377,0.0000030334775,0.000058107773,0.00023143986],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99167603,0.00496927,0.0003370163,0.00095610064,0.001057032,0.0010045765],"domain_scores_gemma":[0.99133795,0.0074106893,0.00013698621,0.00047560304,0.0003369649,0.0003017956],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0014491703,0.00033417417,0.0004101269,0.00049484475,0.00072557485,0.00033600198,0.0007010995,0.0001238003,0.00012024704],"category_scores_gemma":[0.015898082,0.00023838948,0.00005163625,0.0020194924,0.0021978875,0.00030367455,0.0005831179,0.0010602725,0.00013646446],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.13425317,0.0019525436,0.036889486,0.00007371104,0.00008450315,0.00080264825,0.0069090505,0.000006593126,0.8111446,0.001691953,0.0035216007,0.0026701246],"study_design_scores_gemma":[0.02421374,0.005067936,0.6810384,0.0003394502,0.000017251552,0.00006152082,0.001052539,0.0011964996,0.28411448,0.0016446804,0.0005220432,0.0007314512],"about_ca_topic_score_codex":0.00039326373,"about_ca_topic_score_gemma":0.0009794272,"teacher_disagreement_score":0.64414895,"about_ca_system_score_codex":0.00010472663,"about_ca_system_score_gemma":0.00021955922,"threshold_uncertainty_score":0.9923914},"labels":[],"label_agreement":null},{"id":"W2897606585","doi":"10.1016/j.psychres.2018.10.022","title":"Low-grade inflammation in first-episode psychosis is determined by increased waist circumference","year":2018,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Academy of Finland; H. Lundbeck A/S; Helsingin ja Uudenmaan Sairaanhoitopiiri","keywords":"Waist; Internal medicine; Medicine; Anthropometry; C-reactive protein; Abdominal obesity; Insulin resistance; Endocrinology; Population; Metabolic syndrome; Obesity; Apolipoprotein B; Circumference; Cholesterol; Inflammation","score_opus":0.055869693691156026,"score_gpt":0.3528879311597369,"score_spread":0.29701823746858086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897606585","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824571,0.000088108434,0.00008572792,0.009651671,0.00048084735,0.00059640454,0.00003748149,0.00009841817,0.0065042553],"genre_scores_gemma":[0.9977382,0.00011132196,0.00019122518,0.00096553215,0.00032149814,0.000149846,0.000008287633,0.000036749854,0.00047736283],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964145,0.0004557238,0.00041843107,0.00086117856,0.0009528165,0.0008973791],"domain_scores_gemma":[0.9984408,0.00042817715,0.00008304113,0.0007068994,0.00010942055,0.00023165648],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00075010426,0.00022320561,0.00020840831,0.0004930557,0.00047477777,0.0001865012,0.0009159544,0.000170143,0.0007462089],"category_scores_gemma":[0.0008022709,0.00021955636,0.00007712286,0.0018017808,0.000604461,0.0003163665,0.00013302696,0.0005479951,0.0009901619],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005644445,0.0012540792,0.38451555,0.00030352463,0.000012941879,0.000011280439,0.0014908843,0.0000015177426,0.3794719,0.0017935644,0.21832852,0.0122518],"study_design_scores_gemma":[0.006571838,0.0013185312,0.22549494,0.0005576015,0.000009006194,0.000024640627,0.000562639,0.0062873657,0.6786508,0.02869628,0.050446905,0.0013794509],"about_ca_topic_score_codex":0.0011369983,"about_ca_topic_score_gemma":0.004650646,"teacher_disagreement_score":0.2991789,"about_ca_system_score_codex":0.000087842294,"about_ca_system_score_gemma":0.000087557826,"threshold_uncertainty_score":0.9997877},"labels":[],"label_agreement":null},{"id":"W2897661184","doi":"10.1038/s41398-018-0270-z","title":"GSK3β: a plausible mechanism of cognitive and hippocampal changes induced by erythropoietin treatment in mood disorders?","year":2018,"lang":"en","type":"review","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Mood disorders; Mood; Erythropoietin; Bipolar disorder; Cognition; Hippocampal formation; Major depressive disorder; Mechanism (biology); Medicine; Mood stabilizer; Psychology; Psychiatry; Clinical psychology; Oncology; Bioinformatics; Neuroscience; Anxiety; Internal medicine; Biology","score_opus":0.04980401859518814,"score_gpt":0.325675941095419,"score_spread":0.27587192250023085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897661184","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0071596694,0.9855469,0.00010167186,0.0008462507,0.0005358668,0.0021151402,0.001229296,0.00005951605,0.0024057045],"genre_scores_gemma":[0.025464015,0.97351414,0.00025105535,0.000100804195,0.0001353642,0.00020473397,0.00016657352,0.00007131663,0.00009201253],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99780536,0.00024640464,0.00051594124,0.00076318544,0.0003341282,0.00033497636],"domain_scores_gemma":[0.9989956,0.00045308305,0.0002886932,0.00015312486,0.000018670997,0.000090796246],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000113644564,0.0005012443,0.00092535274,0.00031942193,0.00009754741,0.000025007204,0.00019501032,0.00034694397,0.00017759012],"category_scores_gemma":[0.000038378545,0.00043242786,0.00022746473,0.00051164237,0.00021000022,0.00008963993,0.000021321846,0.00024100642,0.000027291568],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004548451,0.004693976,0.0003465003,0.0133010475,0.00038732123,0.000002724673,0.003455481,8.7504753e-7,0.0005248169,0.04066247,0.0006963326,0.9354736],"study_design_scores_gemma":[0.051641475,0.016116317,0.0025785686,0.086739734,0.0039915303,0.00024631576,0.0035878427,0.0003331203,0.0036987143,0.35416177,0.46490428,0.012000336],"about_ca_topic_score_codex":0.00004413825,"about_ca_topic_score_gemma":0.0016064226,"teacher_disagreement_score":0.9234733,"about_ca_system_score_codex":0.000029052468,"about_ca_system_score_gemma":0.00034848778,"threshold_uncertainty_score":0.9998127},"labels":[],"label_agreement":null},{"id":"W2898215351","doi":"10.1159/000493399","title":"Diet and Psychosis: A Scoping Review","year":2018,"lang":"en","type":"review","venue":"Neuropsychobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health; Canadian College of Naturopathic Medicine","funders":"","keywords":"Vitamin B12; Observational study; Medicine; Mental health; Psychological intervention; Vitamin D and neurology; Environmental health; Psychiatry; Internal medicine","score_opus":0.09864511976557908,"score_gpt":0.39577714823059795,"score_spread":0.29713202846501885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898215351","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000004877288,0.99212563,0.000003938794,0.00016153105,0.0013802309,0.0018887008,0.000035446792,0.00015692598,0.0042427005],"genre_scores_gemma":[0.0000012899752,0.9908985,0.000028011258,0.008207554,0.0002732177,0.00029190915,0.000012219154,0.00008262058,0.0002046883],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962024,0.000962425,0.0007306845,0.0014629727,0.000114983246,0.0005264999],"domain_scores_gemma":[0.9980585,0.0005711065,0.0004284201,0.0007771677,0.000021046593,0.0001437512],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001907945,0.00056778383,0.0017815651,0.00016910506,0.00013695343,0.000040927807,0.00066408433,0.00031878916,0.00027320258],"category_scores_gemma":[0.000746836,0.00043034626,0.00034801915,0.00053297763,0.0005122237,0.00006158674,0.00018367758,0.00048100037,0.00094686006],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016172362,0.000064324646,5.476717e-7,0.12907936,0.000015555324,0.000026137017,0.000010603915,1.389025e-9,0.000028512746,0.00019709449,0.02789403,0.84266764],"study_design_scores_gemma":[0.00011859365,0.0003017341,8.269625e-7,0.19994335,0.00007918622,0.0002481474,3.8041475e-7,9.4631595e-8,0.0000024516328,0.0000487435,0.7989404,0.00031604615],"about_ca_topic_score_codex":0.0000010830099,"about_ca_topic_score_gemma":0.000003380211,"teacher_disagreement_score":0.8423516,"about_ca_system_score_codex":0.0000117229,"about_ca_system_score_gemma":0.000078779216,"threshold_uncertainty_score":0.999831},"labels":[],"label_agreement":null},{"id":"W2898670454","doi":"10.1089/wound.2018.0811","title":"Local Expression of Indoleamine 2,3, Dioxygenase Prolongs Allogenic Skin Graft Take in a Mouse Model","year":2018,"lang":"en","type":"article","venue":"Advances in Wound Care","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"University of British Columbia; Canadian Institutes of Health Research; WorkSafeBC","keywords":"Indoleamine 2,3-dioxygenase; CD11c; Immunosuppression; Immunogenicity; Medicine; Kynurenine; Immune system; Immune tolerance; Immunology; Infiltration (HVAC); Biology; Phenotype","score_opus":0.01217504659501985,"score_gpt":0.27038208399844216,"score_spread":0.2582070374034223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898670454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959165,0.0012085128,0.0014246124,0.000021064097,0.000082270395,0.00034557912,0.00003226257,0.000034416782,0.00093481696],"genre_scores_gemma":[0.9987856,0.00022301967,0.00047202225,0.0002494175,0.000027008253,0.00005825424,0.00000498362,0.000020874499,0.00015879638],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855405,0.0000776986,0.00029691542,0.00046340362,0.00027238193,0.00033554013],"domain_scores_gemma":[0.9994119,0.00007393093,0.00009726474,0.0003179121,0.00004314206,0.00005587112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000071661954,0.00017030457,0.00021556203,0.00016127797,0.00004731532,0.000012024289,0.00035695432,0.000093412054,0.00001910086],"category_scores_gemma":[0.00016437791,0.00015260934,0.000053961343,0.00038279366,0.00043766122,0.00037579262,0.00011215717,0.00018435535,0.000009352166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041623556,0.00029758905,0.0010631637,0.00016827162,0.0000012509249,0.00002944318,0.0064157867,0.008792769,0.9587903,0.00046158629,0.00003151563,0.023532106],"study_design_scores_gemma":[0.0011358069,0.00018180684,0.00034655,0.00007368172,7.6721125e-7,0.0000028959805,0.0018148932,0.0021406296,0.99209327,0.0011184331,0.0009031788,0.00018809903],"about_ca_topic_score_codex":0.000022364642,"about_ca_topic_score_gemma":0.0013120623,"teacher_disagreement_score":0.033302974,"about_ca_system_score_codex":0.00006898541,"about_ca_system_score_gemma":0.000054523283,"threshold_uncertainty_score":0.62232286},"labels":[],"label_agreement":null},{"id":"W2898947357","doi":"10.1016/j.freeradbiomed.2018.10.357","title":"Thioredoxin-interacting protein, a potential pharmacological target for the treatment of depression","year":2018,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"TXNIP; Thioredoxin-Interacting Protein; Thioredoxin; Oxidative stress; Inflammation; Downregulation and upregulation; Neuroinflammation; Chemistry; Cell biology; Endocrinology; Biology; Internal medicine; Immunology; Medicine; Biochemistry","score_opus":0.03266222002745145,"score_gpt":0.3405705131144647,"score_spread":0.30790829308701323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898947357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98023635,0.0013914936,0.0060373377,0.010266407,0.000718789,0.0008114628,0.000021975384,0.00003740039,0.00047879008],"genre_scores_gemma":[0.9976869,0.00022178175,0.00031911986,0.000904109,0.0006811042,0.00006321842,0.0000034263755,0.000004415665,0.00011587611],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927384,0.0000981493,0.00016283446,0.00021338684,0.000062596046,0.00018921256],"domain_scores_gemma":[0.9990285,0.00069231045,0.00007288733,0.00011860938,0.00001897244,0.000068743095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012375062,0.00009676699,0.0001799797,0.000028583767,0.00020157307,0.0000024002766,0.00016401397,0.000089691544,0.00028946507],"category_scores_gemma":[0.000992448,0.000042801235,0.00004253877,0.00006054324,0.0015593781,0.000019922676,0.00003371036,0.00007230909,0.0000021418628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058699254,0.00015848335,0.00013430725,0.000006347812,0.000017217131,0.0000037683774,0.00025648603,2.3984362e-7,0.9427548,0.0012916769,0.0019657877,0.052823864],"study_design_scores_gemma":[0.005748683,0.0073622977,0.001748372,0.000034331668,0.00005529899,0.00003989153,0.0001326972,0.0011218265,0.8668341,0.0073634903,0.109458975,0.00010001945],"about_ca_topic_score_codex":0.000012772483,"about_ca_topic_score_gemma":0.0000023306022,"teacher_disagreement_score":0.107493185,"about_ca_system_score_codex":0.000006981731,"about_ca_system_score_gemma":0.00001368586,"threshold_uncertainty_score":0.5745594},"labels":[],"label_agreement":null},{"id":"W2899875342","doi":"10.1016/j.neuron.2018.10.039","title":"Inflamed Astrocytes: A Path to Depression Led by Menin","year":2018,"lang":"en","type":"letter","venue":"Neuron","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Neuroinflammation; Depression (economics); Neuroscience; Mood; Psychology; Inflammation; Neuron; Mood disorders; Medicine; Psychiatry; Internal medicine; Anxiety","score_opus":0.016098652128380974,"score_gpt":0.2478895015576126,"score_spread":0.23179084942923164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899875342","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3745168,0.00019913595,0.00041229176,0.5940124,0.0048047174,0.0029009022,0.0004572012,0.001370404,0.021326156],"genre_scores_gemma":[0.021402324,0.000027912607,0.00009710931,0.9666583,0.0018387273,0.000106707485,0.000058197675,0.00013899975,0.00967171],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99702656,0.00026937836,0.0002852547,0.0011116728,0.00064514973,0.0006619607],"domain_scores_gemma":[0.9987421,0.00026151963,0.00016077096,0.0006749306,0.000026084861,0.00013456112],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000056963745,0.00043404906,0.00033226822,0.00016484945,0.00014456664,0.00013374948,0.00079831417,0.0004491363,0.00033340912],"category_scores_gemma":[0.0005697004,0.00038593996,0.0001271428,0.0002700347,0.000109779,0.00011447343,0.00025076725,0.0011054819,0.0011310843],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034369703,0.000019004365,0.000009021663,0.000028575556,0.0000014252339,0.00010373866,0.00006072766,5.193692e-7,0.25613225,7.3189744e-7,0.7423692,0.0012404367],"study_design_scores_gemma":[0.0003942657,0.00022821,0.00007919459,0.00007337304,0.0000059928157,0.0000098195,0.0000029788343,0.000015407568,0.21772256,0.000014134315,0.78115904,0.00029498906],"about_ca_topic_score_codex":0.000010743519,"about_ca_topic_score_gemma":0.000002695992,"teacher_disagreement_score":0.3726459,"about_ca_system_score_codex":0.000042493495,"about_ca_system_score_gemma":0.00004948575,"threshold_uncertainty_score":0.9998593},"labels":[],"label_agreement":null},{"id":"W2900338538","doi":"10.1016/j.jpsychires.2018.11.008","title":"Immunomodulatory effects of antipsychotic treatment on gene expression in first-episode psychosis","year":2018,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Academy of Finland; Jalmari ja Rauha Ahokkaan Säätiö; Helsingin Yliopisto; Yrjö Jahnssonin Säätiö; Juho Vainion Säätiö; Helsingin ja Uudenmaan Sairaanhoitopiiri","keywords":"Psychosis; Antipsychotic; Psychology; Schizophrenia (object-oriented programming); Psychiatry; Medicine; Pharmacology","score_opus":0.04989732715511975,"score_gpt":0.367051020541765,"score_spread":0.3171536933866453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900338538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99523324,0.0010517874,0.00008832126,0.0007059142,0.0012123887,0.00037815445,0.0000019320967,0.0000074981526,0.0013207705],"genre_scores_gemma":[0.9966815,0.0018501261,0.0008334381,0.00007950711,0.0003823735,0.000010856429,1.4455323e-7,0.000024309416,0.00013774443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99693197,0.0005908666,0.0006262975,0.0003352414,0.0010465427,0.00046905436],"domain_scores_gemma":[0.9979936,0.00092174136,0.0003143029,0.0004621194,0.00015894347,0.00014928063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008220914,0.00017025975,0.0003394491,0.0014033667,0.00017495589,0.000034860703,0.00059001,0.00010602084,0.00007341842],"category_scores_gemma":[0.00052779185,0.00012230151,0.00020014972,0.0014502585,0.00024682542,0.00012761477,0.00003987047,0.0004378307,0.000062057334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004307141,0.0056775543,0.042959478,0.00027033768,0.000043337048,0.00013736343,0.0013909388,0.00009182492,0.9033056,0.00033641548,0.019927118,0.021552928],"study_design_scores_gemma":[0.005156599,0.0086057605,0.11445918,0.00032963976,0.000008353929,0.000032912085,0.000070283684,0.00006037221,0.8665284,0.0020353196,0.002547545,0.00016563428],"about_ca_topic_score_codex":0.00005269777,"about_ca_topic_score_gemma":0.000028466517,"teacher_disagreement_score":0.071499705,"about_ca_system_score_codex":0.00014521196,"about_ca_system_score_gemma":0.00007444124,"threshold_uncertainty_score":0.49873108},"labels":[],"label_agreement":null},{"id":"W2900449902","doi":"10.1038/s41386-018-0277-4","title":"VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine","year":2018,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université Laval","funders":"National Center for Complementary and Integrative Health; National Institutes of Health; Hope for Depression Research Foundation; National Institute of Mental Health; BrightFocus Foundation","keywords":"Prefrontal cortex; Psychology; Ventromedial prefrontal cortex; Neuroscience; Depression (economics); Ketamine; Terminal (telecommunication); Cognition","score_opus":0.011839041363434553,"score_gpt":0.2952249570872306,"score_spread":0.28338591572379607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900449902","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952118,0.0001505775,0.0000013684183,0.0019711396,0.0013691997,0.0008287015,0.000014755264,0.00006179179,0.00039070324],"genre_scores_gemma":[0.99522597,0.00009469881,0.000012995804,0.0034357128,0.00012465112,0.00007244093,9.987234e-7,0.0000333304,0.0009992283],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9972697,0.000967714,0.00035243877,0.00073594745,0.00020660514,0.00046759323],"domain_scores_gemma":[0.9987867,0.00063947705,0.00010980464,0.0002172974,0.000027883825,0.00021885366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033790516,0.00023764276,0.00027312536,0.00021778776,0.00020883245,0.00003887123,0.00032689268,0.0001111278,0.0002528255],"category_scores_gemma":[0.0004484264,0.00018288485,0.000043717802,0.0003778786,0.0007954437,0.00012641924,0.00023093935,0.0003706256,0.00008224323],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012239208,0.00012118151,0.0006021217,0.000005600396,0.0000046370837,0.0003352644,0.0010395484,0.0000016477312,0.98258275,0.000040167488,0.0005620324,0.0024658176],"study_design_scores_gemma":[0.013226664,0.00080628804,0.9512639,0.000022234088,0.00003703056,0.0005851429,0.000036183883,0.00065399526,0.030260295,0.00015193713,0.0026931851,0.00026316175],"about_ca_topic_score_codex":0.000008428729,"about_ca_topic_score_gemma":0.000020019696,"teacher_disagreement_score":0.9523225,"about_ca_system_score_codex":0.000021136098,"about_ca_system_score_gemma":0.000034732155,"threshold_uncertainty_score":0.7457828},"labels":[],"label_agreement":null},{"id":"W2900663308","doi":"10.1101/469023","title":"Genetic variation in the Major Histocompatibility Complex and association with depression","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of Mental Health; Medical Research Council; King's Health Partners; King's College London; National Institute for Health and Care Research; Maudsley Charity; Department of Health and Social Care; South London and Maudsley NHS Foundation Trust","keywords":"Human leukocyte antigen; Depression (economics); Major histocompatibility complex; Major depressive disorder; Haplotype; Allele; Genome-wide association study; Medicine; Biology; Genetics; Psychiatry; Single-nucleotide polymorphism; Gene; Genotype; Antigen; Cognition","score_opus":0.02141907236782517,"score_gpt":0.23135123146568717,"score_spread":0.209932159097862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900663308","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99719965,0.0001004601,0.00087106175,0.00027420334,0.0002287684,0.0011252727,0.000051808172,0.000120951205,0.00002782173],"genre_scores_gemma":[0.9972519,0.000022446076,0.0018191402,0.00055712205,0.00013985274,0.0001695181,1.1144271e-7,0.000038275968,0.0000015876753],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99736595,0.00053209864,0.00033632884,0.00091369246,0.000512755,0.00033918236],"domain_scores_gemma":[0.99831814,0.0002643779,0.00043501065,0.00078106,0.00012602653,0.000075391836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068428693,0.00030477077,0.00028478343,0.00014016283,0.00020216143,0.0002195708,0.00045894732,0.0002840938,0.00003813935],"category_scores_gemma":[0.0006059241,0.00023551435,0.000041285126,0.0003933026,0.00013447934,0.0001171178,0.00021139742,0.0004827195,0.000017918597],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006669369,0.00022769853,0.16552092,0.00016966899,0.000015314805,0.00001465959,0.00011688976,0.00003638899,0.83332086,0.00014101958,0.00036599633,0.0000038978965],"study_design_scores_gemma":[0.0005828975,0.000043680244,0.96019554,0.00008770507,0.000024629444,1.7045537e-8,0.0000023054931,0.0010542794,0.03738237,0.000015525222,0.00031729686,0.0002937712],"about_ca_topic_score_codex":0.000111946516,"about_ca_topic_score_gemma":0.000031101714,"teacher_disagreement_score":0.7959385,"about_ca_system_score_codex":0.0003101716,"about_ca_system_score_gemma":0.00016869775,"threshold_uncertainty_score":0.9603997},"labels":[],"label_agreement":null},{"id":"W2900941483","doi":"","title":"Biomarcadores de estrés e inflamación en la psicosis temprana","year":2017,"lang":"es","type":"dissertation","venue":"TDX (Tesis Doctorals en Xarxa)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Humanities; Medicine; Persona; Philosophy","score_opus":0.025817117291838224,"score_gpt":0.33934276074014763,"score_spread":0.3135256434483094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900941483","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9709496,0.001041562,0.000018414477,0.0010948766,0.0016675115,0.0010103643,0.00036977598,0.00043740417,0.023410527],"genre_scores_gemma":[0.98117125,0.0024906974,0.00036405705,0.0005022352,0.00062900997,0.0002019219,0.00032023696,0.00027039324,0.014050204],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99264103,0.0016349854,0.0010889051,0.001888887,0.0012174463,0.001528733],"domain_scores_gemma":[0.99325675,0.002950023,0.0011732026,0.0018741937,0.00017512881,0.0005706853],"candidate_categories":["metaepi_narrow","scholarly_communication","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.001080947,0.0013857454,0.0013360567,0.00082395645,0.0011337138,0.001571179,0.0030322336,0.0014259325,0.0011053066],"category_scores_gemma":[0.004831739,0.001390388,0.00080555567,0.0006292767,0.00067130604,0.0008762225,0.00025115372,0.0011695692,0.0010976049],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007043455,0.0010971248,0.05213258,0.0020403503,0.0005542592,0.00062615215,0.006848417,0.00004896598,0.7652005,0.008256279,0.016389608,0.14610142],"study_design_scores_gemma":[0.00204939,0.0003301488,0.46882898,0.0012946542,0.0004774776,0.000057153356,0.0008274805,0.0002348081,0.42220423,0.0013487005,0.099804156,0.002542833],"about_ca_topic_score_codex":0.0013860379,"about_ca_topic_score_gemma":0.00043540393,"teacher_disagreement_score":0.4166964,"about_ca_system_score_codex":0.0002661272,"about_ca_system_score_gemma":0.00071301014,"threshold_uncertainty_score":0.9998893},"labels":[],"label_agreement":null},{"id":"W2901198337","doi":"10.2174/1568026618666181115101625","title":"Common Environmental Factors May Underpin the Comorbidity Between Generalized Anxiety Disorder and Mood Disorders Via Activated Nitrooxidative Pathways","year":2018,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Comorbidity; Bipolar disorder; Generalized anxiety disorder; Mood disorders; Major depressive disorder; Mood; Anxiety; Psychology; Depression (economics); Clinical psychology; Psychiatry; Medicine","score_opus":0.07303532240738458,"score_gpt":0.330020257336779,"score_spread":0.2569849349293944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901198337","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20289706,0.7939776,0.00007636782,0.00016091362,0.000568673,0.0011168561,0.00039917277,0.00008100532,0.0007223538],"genre_scores_gemma":[0.14223336,0.85662407,0.0000067466053,0.000027422766,0.00039891584,0.00006708258,0.00052922237,0.000049925904,0.00006327453],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968631,0.00042002287,0.000682861,0.00093255995,0.0005529313,0.0005484897],"domain_scores_gemma":[0.9982349,0.00052912824,0.00043326276,0.0006030819,0.000007706259,0.00019190005],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023698597,0.0007342675,0.001180422,0.00006644785,0.0002886191,0.000053198895,0.0008549055,0.00039908395,0.00015900668],"category_scores_gemma":[0.00021949664,0.0004992719,0.00027007787,0.0003279202,0.0011775306,0.000094087314,0.0004050159,0.0015568619,0.00000794278],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021621387,0.0004534175,0.008538925,0.0059283357,0.000080218095,0.0000041142334,0.000687662,4.3474722e-7,0.0013326199,0.000051626197,0.00036831768,0.9825327],"study_design_scores_gemma":[0.0017068987,0.000085818356,0.0024689515,0.0034007868,0.00031223116,0.000021910948,0.0006007835,0.000024538782,0.006741082,0.0014819256,0.98192835,0.0012267468],"about_ca_topic_score_codex":0.000026801468,"about_ca_topic_score_gemma":0.000022533626,"teacher_disagreement_score":0.98156,"about_ca_system_score_codex":0.00022947023,"about_ca_system_score_gemma":0.000103313345,"threshold_uncertainty_score":0.9997459},"labels":[],"label_agreement":null},{"id":"W2901327393","doi":"10.1177/2045125318791944","title":"Anti-cytokine agents for anhedonia: targeting inflammation and the immune system to treat dimensional disturbances in depression","year":2018,"lang":"en","type":"review","venue":"Therapeutic Advances in Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Anhedonia; Neuroscience; Medicine; Mood disorders; Bipolar disorder; Major depressive disorder; Mood; Neurology; Psychology; Bioinformatics; Schizophrenia (object-oriented programming); Psychiatry; Biology","score_opus":0.03277038574245015,"score_gpt":0.3772178966809679,"score_spread":0.3444475109385177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901327393","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0041179587,0.9902603,0.00019812901,0.00014152146,0.0016921366,0.0032804385,0.000034128654,0.00005222528,0.00022318523],"genre_scores_gemma":[0.02948329,0.96836555,0.00014392851,0.00030462333,0.00029602833,0.0012653222,0.000015897773,0.000052760803,0.000072595365],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99675524,0.00081971945,0.0008993638,0.0008337735,0.00020013915,0.00049177057],"domain_scores_gemma":[0.9974959,0.001693012,0.00047191815,0.00025122566,0.00002731385,0.000060641636],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006439689,0.00045193773,0.0012843179,0.000303023,0.00019745408,0.000032874945,0.0005373793,0.00019904008,0.000021807233],"category_scores_gemma":[0.000109865774,0.00028357495,0.00016359778,0.00059704686,0.00040423608,0.00020912023,0.00012217973,0.00032465244,0.00001744411],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001358649,0.000099163866,0.000023250108,0.004745571,0.000023577291,0.000013329006,0.00032023035,0.00011553609,0.0012296459,0.0008688147,0.000095166535,0.99110705],"study_design_scores_gemma":[0.0070732306,0.00011363295,0.000056686236,0.0031353587,0.00012345747,0.00003286943,0.00006684808,0.0005466565,0.00091611635,0.0006621824,0.9868292,0.00044376715],"about_ca_topic_score_codex":0.000004583207,"about_ca_topic_score_gemma":0.000008823466,"teacher_disagreement_score":0.9906633,"about_ca_system_score_codex":0.00012126961,"about_ca_system_score_gemma":0.000046303252,"threshold_uncertainty_score":0.9999616},"labels":[],"label_agreement":null},{"id":"W2901651562","doi":"10.2174/1871527317666181119115532","title":"A New Schizophrenia Model: Immune Activation is Associated with the Induction of Different Neurotoxic Products which Together Determine Memory Impairments and Schizophrenia Symptom Dimensions","year":2018,"lang":"en","type":"article","venue":"CNS & Neurological Disorders - Drug Targets","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Asahi Glass Foundation","keywords":"Schizophrenia (object-oriented programming); Neuroscience; Psychology; Medicine; Psychiatry","score_opus":0.015378636116954392,"score_gpt":0.23011531357064077,"score_spread":0.21473667745368638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901651562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990472,0.00008890328,0.00021097911,0.007345628,0.0001952892,0.0013132322,0.000018192139,0.00019988586,0.00015587233],"genre_scores_gemma":[0.997507,0.00007134012,0.00014522248,0.0018092341,0.000075108524,0.00007620681,0.000010910955,0.000062324,0.0002426994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968203,0.000485593,0.00043552803,0.0010745745,0.0005695448,0.0006145102],"domain_scores_gemma":[0.9983668,0.00032462715,0.0003851407,0.00061334483,0.00012946407,0.0001806371],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001735699,0.0005026675,0.00046133954,0.0001648476,0.0005044595,0.000076449105,0.00050385075,0.00017621431,0.00008121658],"category_scores_gemma":[0.0009988635,0.00031065478,0.00009942758,0.00090591627,0.000661075,0.0003410154,0.00030555003,0.0005720714,0.000010758424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033857336,0.0014261904,0.0015530629,0.000035354853,0.000079377845,0.000010176359,0.0025563103,0.0003410052,0.9745142,0.00025863896,0.0023479727,0.013491966],"study_design_scores_gemma":[0.01286979,0.0053982576,0.29572478,0.00015826826,0.00020951666,0.00006231509,0.0002617144,0.037380014,0.63237196,0.013539335,0.00029297054,0.0017310772],"about_ca_topic_score_codex":0.000023644241,"about_ca_topic_score_gemma":0.000090666974,"teacher_disagreement_score":0.34214225,"about_ca_system_score_codex":0.000022991864,"about_ca_system_score_gemma":0.000099750716,"threshold_uncertainty_score":0.99993455},"labels":[],"label_agreement":null},{"id":"W2901954088","doi":"10.1017/s1092852918001207","title":"Cognitive impairment in major depressive disorder","year":2018,"lang":"en","type":"review","venue":"CNS Spectrums","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":304,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University of Toronto; University Health Network","funders":"","keywords":"Cognition; Major depressive disorder; Psychology; Mood; Working memory; Psychosocial; Executive functions; Clinical psychology; Quality of life (healthcare); Mood disorders; Executive dysfunction; Psychiatry; Medicine; Anxiety; Psychotherapist; Neuropsychology","score_opus":0.03741818655652591,"score_gpt":0.32269208056060145,"score_spread":0.28527389400407555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901954088","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003804661,0.98600316,0.000031739673,0.000064038795,0.0004898035,0.0018328181,0.00014090087,0.00012312549,0.010933931],"genre_scores_gemma":[0.00077772187,0.9969022,0.000015235582,0.00031574364,0.0002539119,0.00032510803,0.00003400544,0.00009881071,0.0012772501],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969878,0.0003053081,0.0005467383,0.0011156243,0.0003224151,0.00072210724],"domain_scores_gemma":[0.99861634,0.0004618659,0.00031047527,0.00045669562,0.00001777633,0.000136834],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000113722985,0.00058750884,0.001141645,0.00038202343,0.00014059247,0.0000904652,0.00064130384,0.0002892354,0.0009731418],"category_scores_gemma":[0.00043156417,0.0004715046,0.0004397376,0.0008440622,0.0003531513,0.00016278654,0.00025676726,0.00054819864,0.0021034826],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006659489,0.0010709612,0.00006440038,0.0071510156,0.000087465836,0.00051373197,0.0004965506,3.3864316e-7,0.000015204788,0.0028412035,0.0039743194,0.9837182],"study_design_scores_gemma":[0.0014048074,0.00022409458,0.00010132732,0.007992907,0.00013668915,0.00009144752,0.000088624394,0.0000056600265,0.00030211432,0.0010473105,0.98771137,0.0008936681],"about_ca_topic_score_codex":0.000029515657,"about_ca_topic_score_gemma":0.00012761122,"teacher_disagreement_score":0.98373705,"about_ca_system_score_codex":0.00015304021,"about_ca_system_score_gemma":0.00022896435,"threshold_uncertainty_score":0.9999401},"labels":[],"label_agreement":null},{"id":"W2902097866","doi":"10.1007/s12035-018-1437-6","title":"In Schizophrenia, Deficits in Natural IgM Isotype Antibodies Including those Directed to Malondialdehyde and Azelaic Acid Strongly Predict Negative Symptoms, Neurocognitive Impairments, and the Deficit Syndrome","year":2018,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Chulalongkorn University; Asahi Glass Foundation","keywords":"Immunology; Schizophrenia (object-oriented programming); Antibody; Autoantibody; Internal medicine; Malondialdehyde; Cognitive deficit; Medicine; Oxidative stress; Psychiatry; Disease","score_opus":0.01062472894684586,"score_gpt":0.2552898347417257,"score_spread":0.24466510579487982,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902097866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99710613,0.00035869158,0.000021776237,0.000840466,0.000303349,0.0010483311,0.00003945459,0.0000859488,0.00019586597],"genre_scores_gemma":[0.99639386,0.00008096709,0.00009319296,0.0032832953,0.000021996859,0.000061016774,0.0000057969214,0.0000375366,0.000022333114],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9969017,0.0010463624,0.00035666945,0.0009150572,0.00014042776,0.0006397648],"domain_scores_gemma":[0.99891347,0.0005882265,0.000113280556,0.00024446295,0.000043409313,0.00009715677],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020431854,0.00036116963,0.0004532955,0.00041796122,0.00018144712,0.00007010968,0.00032229224,0.00012867032,0.000010033816],"category_scores_gemma":[0.0014377042,0.00028295442,0.00005409363,0.0007779998,0.0009981061,0.00017422464,0.00055854995,0.00048639296,0.000020241076],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003247123,0.0001815279,0.010513625,0.000039203394,0.000034970675,0.00096019637,0.0024638374,0.000034828292,0.9793932,0.0016254683,0.00005833765,0.0014476686],"study_design_scores_gemma":[0.020707406,0.0038764246,0.6661306,0.00031731272,0.000070549955,0.0018352256,0.0005138296,0.0022183673,0.2988932,0.0038366204,0.00018469822,0.0014157387],"about_ca_topic_score_codex":0.00007895544,"about_ca_topic_score_gemma":0.00025454626,"teacher_disagreement_score":0.68050003,"about_ca_system_score_codex":0.000030274585,"about_ca_system_score_gemma":0.000042532873,"threshold_uncertainty_score":0.9999623},"labels":[],"label_agreement":null},{"id":"W2903318803","doi":"10.1016/j.bbr.2018.12.003","title":"Lipopolysaccharide (LPS) induced sickness in early adolescence alters the behavioral effects of the short-chain fatty acid, propionic acid, in late adolescence and adulthood: Examining anxiety and startle reactivity","year":2018,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Prepulse inhibition; Startle response; Anxiety; Anxiogenic; Psychology; Acoustic Startle Reflex; Lipopolysaccharide; Internal medicine; Endocrinology; Startle reaction; Elevated plus maze; Immune system; Anxiolytic; Physiology; Medicine; Reflex; Psychiatry; Immunology; Schizophrenia (object-oriented programming)","score_opus":0.0900820965878014,"score_gpt":0.3432385914074584,"score_spread":0.25315649481965696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2903318803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972672,0.000099804536,0.000009262702,0.0007696571,0.00013726317,0.0016556489,0.000012302436,0.00003227925,0.000016587928],"genre_scores_gemma":[0.99952054,0.000058801143,0.000034187866,0.00017398632,0.000031647825,0.0001174231,8.078936e-7,0.000033631186,0.000028966879],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99506485,0.0017570152,0.00040820066,0.0008895685,0.0009359447,0.0009444125],"domain_scores_gemma":[0.9982396,0.00069303194,0.00011537652,0.00067894737,0.00010638003,0.00016668085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019460355,0.00029549166,0.0003273202,0.00024320575,0.00042394924,0.00015123392,0.00084176695,0.00018913332,0.0000056353197],"category_scores_gemma":[0.0014424388,0.00020164163,0.00005595215,0.0011399382,0.0017376046,0.00045637888,0.0007750619,0.0014327585,0.0000037657462],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011040773,0.00016016305,0.35727325,0.00004996646,9.1602766e-7,0.000019346671,0.0032556655,3.4662568e-7,0.62248296,0.000038859333,0.000006622982,0.016601492],"study_design_scores_gemma":[0.00053625734,0.0002430932,0.5331957,0.00028481032,0.000003148997,0.000008294946,0.00045961424,0.00010272845,0.46496883,0.00006013892,0.0000010486012,0.0001363728],"about_ca_topic_score_codex":0.0018161624,"about_ca_topic_score_gemma":0.002594368,"teacher_disagreement_score":0.17592241,"about_ca_system_score_codex":0.000112273134,"about_ca_system_score_gemma":0.00017543203,"threshold_uncertainty_score":0.8222707},"labels":[],"label_agreement":null},{"id":"W2903482849","doi":"10.1016/j.bbi.2018.11.315","title":"Association of baseline inflammatory markers and the development of negative symptoms in individuals at clinical high risk for psychosis","year":2018,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":73,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Center for Advancing Translational Sciences; National Institute of Mental Health","keywords":"Internal medicine; Psychosis; Depression (economics); Schizophrenia (object-oriented programming); Medicine; Population; Psychology; Gastroenterology; Psychiatry","score_opus":0.027265024399915423,"score_gpt":0.31504412124963654,"score_spread":0.28777909684972114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2903482849","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989082,0.000021698583,0.000036353445,0.00022050703,0.00009408855,0.0005818741,0.000079609694,0.000008181461,0.000049483977],"genre_scores_gemma":[0.99904376,0.00007043521,0.0005303851,0.00016240588,0.000013716552,0.00006624324,0.0000051857833,0.000007717881,0.000100141115],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981354,0.0008440288,0.0005359666,0.00018014974,0.0001609088,0.00014358098],"domain_scores_gemma":[0.99569714,0.0036357483,0.00040573592,0.00016370356,0.00006254284,0.000035147048],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029913865,0.00009966827,0.00023750398,0.00007060815,0.00019865356,0.000011466388,0.00014375284,0.00009919181,0.000026048114],"category_scores_gemma":[0.0035402523,0.00007484486,0.000051374947,0.00014634873,0.00058332755,0.00007488205,0.00011752606,0.00014681186,8.437819e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005134496,0.00023714585,0.95041156,0.000022159544,0.00002331577,6.2248205e-8,0.0038353289,1.2583018e-7,0.007549136,0.00011152236,0.00046689587,0.036829323],"study_design_scores_gemma":[0.004669098,0.00013221668,0.9636874,0.000025543135,0.000029093193,3.0164233e-7,0.0003434295,0.000022506341,0.030451803,0.00023468246,0.0003198065,0.00008408136],"about_ca_topic_score_codex":0.00008947807,"about_ca_topic_score_gemma":0.00036051846,"teacher_disagreement_score":0.036745243,"about_ca_system_score_codex":0.000029974552,"about_ca_system_score_gemma":0.000038147038,"threshold_uncertainty_score":0.42382684},"labels":[],"label_agreement":null},{"id":"W2903961002","doi":"10.1002/jnr.24367","title":"Suicide and suicide behaviors: A review of transcriptomics and multiomics studies in psychiatric disorders","year":2018,"lang":"en","type":"review","venue":"Journal of Neuroscience Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Transcriptome; Epigenetics; Psychiatric Disease; Psychiatry; Disease; Neuroscience; Medicine; Psychology; Bioinformatics; Biology; Gene; Genetics; Gene expression","score_opus":0.3601607610839885,"score_gpt":0.5228554338316769,"score_spread":0.1626946727476884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2903961002","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009990659,0.9882258,0.00000599122,0.00032291035,0.0004634219,0.0009227753,0.000023725283,0.0000062050863,0.000038473354],"genre_scores_gemma":[0.0009977221,0.99849963,0.00013478524,0.00020690523,0.00006489364,0.000018068273,3.110261e-7,0.000038899034,0.00003880043],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99410605,0.001421277,0.0016579027,0.0007295868,0.0013827239,0.00070244813],"domain_scores_gemma":[0.99652797,0.0016393181,0.0009151092,0.00037894916,0.00028290352,0.00025577637],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.004292506,0.00037830404,0.0018314619,0.0018940102,0.00021220802,0.000087695,0.0011351563,0.00016098973,0.000003726729],"category_scores_gemma":[0.00769975,0.0002775046,0.00033830144,0.00327966,0.0030895201,0.00043556074,0.00029872177,0.0014196802,0.0000016600451],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009523244,0.00079374074,0.00037060835,0.1634992,0.000018952254,0.00022238119,0.0007430454,8.492893e-7,0.005900795,0.00024668622,0.0011504339,0.82695806],"study_design_scores_gemma":[0.0030818216,0.0049280007,0.0015579434,0.3827554,0.00055369147,0.0035521637,0.0009894825,0.00008340137,0.0005528568,0.002039262,0.5982459,0.0016600627],"about_ca_topic_score_codex":0.000018095514,"about_ca_topic_score_gemma":0.000035114612,"teacher_disagreement_score":0.825298,"about_ca_system_score_codex":0.00010529646,"about_ca_system_score_gemma":0.0006865285,"threshold_uncertainty_score":0.9999677},"labels":[],"label_agreement":null},{"id":"W2905262222","doi":"10.1016/j.schres.2018.11.035","title":"Investigation of peripheral complement factors across stages of psychosis","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Medical Research Council; National Health and Medical Research Council; Astellas Foundation for Research on Metabolic Disorders; Australian Rotary Health; Australian Research Council; University of New South Wales; Schizophrenia Research Institute; Neuroscience Research Australia; University of Melbourne; Royal Melbourne Hospital; National Alliance for Research on Schizophrenia and Depression","keywords":"Psychosis; Schizophrenia (object-oriented programming); Internal medicine; Pathogenesis; Medicine; Peripheral; Complement system; Psychology; Immunology; Clinical psychology; Psychiatry; Antibody","score_opus":0.16397201624040816,"score_gpt":0.4101735013179245,"score_spread":0.24620148507751635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2905262222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984582,0.000026130236,0.000027638933,0.0003410859,0.00012558991,0.00027932317,0.000096942815,0.000026276846,0.000618782],"genre_scores_gemma":[0.99917656,0.000020528556,0.00046490147,0.000041169587,0.0000628449,0.000013515105,0.0000048068564,0.00001548519,0.00020017735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976235,0.00036072,0.00030264934,0.00034799727,0.00091538124,0.00044975968],"domain_scores_gemma":[0.99887085,0.00029987041,0.00009604864,0.0003775964,0.00024176484,0.00011387198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064020435,0.000109928624,0.00017661999,0.00016769633,0.00025215463,0.000040270563,0.0004990374,0.00005567577,0.00052166235],"category_scores_gemma":[0.00052216573,0.00009317839,0.00006450137,0.00086750195,0.0017206917,0.00013787717,0.00018327522,0.0002161805,0.000029469076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003692539,0.000059872935,0.031538807,0.000058315716,0.0000071454524,6.2360056e-7,0.003676071,0.000001280417,0.9558727,0.0041096406,0.0017376912,0.0025685818],"study_design_scores_gemma":[0.00079966744,0.00041289892,0.11062141,0.00003061527,8.5820875e-7,3.8834966e-7,0.00084322906,0.000049219296,0.8838254,0.0027162614,0.0006150721,0.00008496611],"about_ca_topic_score_codex":0.00021466393,"about_ca_topic_score_gemma":0.00022338152,"teacher_disagreement_score":0.0790826,"about_ca_system_score_codex":0.000034950244,"about_ca_system_score_gemma":0.00009053232,"threshold_uncertainty_score":0.633996},"labels":[],"label_agreement":null},{"id":"W2905498976","doi":"10.1016/j.psychres.2018.11.064","title":"A pilot case-control study on the association between N-acetyl derivatives in serum and first-episode schizophrenia","year":2018,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brain and Cognition Discovery Foundation; University Health Network","funders":"Peking University Health Science Center; Peking University","keywords":"Schizophrenia (object-oriented programming); Metabolite; Internal medicine; Glutamine; Psychology; Medicine; Chemistry; Psychiatry; Biochemistry; Amino acid","score_opus":0.09303930531992627,"score_gpt":0.36480718938540635,"score_spread":0.2717678840654801,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2905498976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9834404,0.000046519363,0.000009805957,0.013689886,0.0002140602,0.0011903566,0.000039995022,0.000043740478,0.0013252182],"genre_scores_gemma":[0.99882334,0.0000102721115,0.000030960648,0.00044195136,0.00035543813,0.00011173402,2.526959e-7,0.000022925742,0.00020314516],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99642104,0.0014886564,0.00023455618,0.0005491605,0.0007056717,0.0006009105],"domain_scores_gemma":[0.99649984,0.002883632,0.00007248777,0.0003790091,0.000071463495,0.000093551185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022329686,0.00015521751,0.0001819134,0.00025530296,0.00084457797,0.00018339603,0.0003782466,0.000057255987,0.000094972595],"category_scores_gemma":[0.0023749112,0.00011232828,0.00003174308,0.001003854,0.0002727879,0.00013815366,0.00012915544,0.0007006513,0.00015439357],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033295254,0.00045971514,0.9928309,0.000011471388,0.000023890318,0.000017081067,0.0013734857,8.464971e-7,0.0012374987,0.0013292814,0.001587323,0.0007955917],"study_design_scores_gemma":[0.002778599,0.0026049947,0.9886134,0.000030970907,0.000005535333,0.00000821647,0.0021702605,0.000104696854,0.0005147394,0.0028340318,0.00018971125,0.00014480866],"about_ca_topic_score_codex":0.000268222,"about_ca_topic_score_gemma":0.0064578177,"teacher_disagreement_score":0.015382902,"about_ca_system_score_codex":0.000082722334,"about_ca_system_score_gemma":0.000059531932,"threshold_uncertainty_score":0.64958966},"labels":[],"label_agreement":null},{"id":"W2907086215","doi":"10.3390/ph12010009","title":"Juvenile Arthritis Patients Suffering from Chronic Inflammation Have Increased Activity of Both IDO and GTP-CH1 Pathways But Decreased BH4 Efficacy: Implications for Well-Being, Including Fatigue, Cognitive Impairment, Anxiety, and Depression","year":2019,"lang":"en","type":"article","venue":"Pharmaceuticals","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universiteit Utrecht; Deutsche Forschungsgemeinschaft; Arthritis Society; Dutch Arthritis Society","keywords":"Neopterin; Kynurenine; GTP cyclohydrolase I; Medicine; Tetrahydrobiopterin; Internal medicine; Inflammation; Kynurenine pathway; Arthritis; Endocrinology; Proinflammatory cytokine; Immunology; Tryptophan; Chemistry; Nitric oxide; Biochemistry; Nitric oxide synthase","score_opus":0.046365216347355916,"score_gpt":0.32815124068534485,"score_spread":0.28178602433798894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2907086215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99563324,0.00022704627,0.0012799939,0.00008540683,0.000074981144,0.0018848258,0.0003707066,0.0000773864,0.00036642738],"genre_scores_gemma":[0.9988174,0.0005871981,0.00012357732,0.00016336385,0.000054796616,0.00014650749,0.00006893161,0.00003297291,0.0000052490714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982705,0.00018650391,0.00035390334,0.0006085536,0.0002117761,0.00036874975],"domain_scores_gemma":[0.99775094,0.0014809527,0.00025359602,0.0001995678,0.000077439654,0.00023750111],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020712001,0.00024192553,0.00033587613,0.00010927709,0.0002483613,0.000072328694,0.00013627762,0.00010087468,0.00007264175],"category_scores_gemma":[0.0007052946,0.00024325664,0.0000758141,0.0001355091,0.0001593898,0.0003867175,0.00021277204,0.00016584496,0.0000060620623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027517838,0.00026187833,0.12730587,0.00011680099,0.000019872241,4.5572236e-7,0.000399712,0.000006958436,0.8149666,0.000117114614,0.000016339258,0.0565132],"study_design_scores_gemma":[0.0064482405,0.00011920372,0.29480094,0.0002197261,0.000038983384,0.0000017607485,0.00004956617,0.0050741485,0.69216853,0.0007467075,0.00010395051,0.00022823422],"about_ca_topic_score_codex":0.00009327708,"about_ca_topic_score_gemma":0.000021948043,"teacher_disagreement_score":0.16749507,"about_ca_system_score_codex":0.00006368489,"about_ca_system_score_gemma":0.000066492255,"threshold_uncertainty_score":0.9919718},"labels":[],"label_agreement":null},{"id":"W2909165991","doi":"10.1080/15622975.2019.1701203","title":"In schizophrenia, psychomotor retardation is associated with executive and memory impairments, negative and psychotic symptoms, neurotoxic immune products and lower natural IgM to malondialdehyde","year":2020,"lang":"en","type":"article","venue":"The World Journal of Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia (object-oriented programming); Psychology; Executive functions; Neurocognitive; Schizoaffective disorder; Cognition; Immunology; Psychiatry; Psychosis; Medicine","score_opus":0.017159342048298675,"score_gpt":0.25119770389560064,"score_spread":0.23403836184730198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2909165991","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9486834,0.0010908595,0.0000038102178,0.04902729,0.00046838543,0.000612397,0.000011578553,0.00001683302,0.00008545745],"genre_scores_gemma":[0.98573667,0.00020965142,0.0003032887,0.01348817,0.00015123874,0.0000067166393,7.0441666e-7,0.000013868813,0.000089701156],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99830776,0.0003772296,0.00037851438,0.00043940975,0.00022286689,0.00027419723],"domain_scores_gemma":[0.9990184,0.00025924554,0.0003405593,0.00013203295,0.000046299243,0.00020350862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003022085,0.00023727985,0.0003587029,0.00014480793,0.00014267061,0.000070176655,0.0002464084,0.00006257942,0.000032425392],"category_scores_gemma":[0.0006515863,0.00013373121,0.00004870369,0.0007684549,0.00036024398,0.00021889551,0.00007755215,0.0006071289,0.0000028098073],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0841643,0.0032845095,0.090819955,0.00028016398,0.00070672855,0.0005643116,0.016704286,0.00005922345,0.743278,0.0029689544,0.035785742,0.021383815],"study_design_scores_gemma":[0.011016624,0.006949109,0.9629621,0.00048529432,0.000071013055,0.00043386195,0.0007033139,0.00012787992,0.008916649,0.0069813067,0.0006172229,0.000735608],"about_ca_topic_score_codex":0.0000026710177,"about_ca_topic_score_gemma":0.000020564023,"teacher_disagreement_score":0.87214214,"about_ca_system_score_codex":0.000019700996,"about_ca_system_score_gemma":0.00004750959,"threshold_uncertainty_score":0.54534006},"labels":[],"label_agreement":null},{"id":"W2909975486","doi":"10.1176/appi.pn.2019.1b6","title":"<i>AJP</i> Editors Select 2018 Favorites","year":2019,"lang":"en","type":"article","venue":"Psychiatric News","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Psychology; Freedman; Psychoanalysis; Medicine; Psychotherapist; Psychiatry; Political science; Law","score_opus":0.01109900702202085,"score_gpt":0.23896291104737383,"score_spread":0.22786390402535298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2909975486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8608145,0.0006440462,0.00014679924,0.0033303767,0.027658278,0.0007231419,0.000019355777,0.0004736551,0.10618985],"genre_scores_gemma":[0.9809646,0.00019495301,0.00056494406,0.0052672694,0.005226992,0.000017137332,0.0000032361093,0.00005179571,0.0077090454],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983963,0.00007517735,0.00022368884,0.0005440086,0.00032844188,0.00043239444],"domain_scores_gemma":[0.9991795,0.00018238518,0.00009552715,0.00041198442,0.000014766982,0.000115869436],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007783089,0.00019243738,0.00017982416,0.00015699345,0.00011140872,0.00006902677,0.00041746927,0.00008558788,0.00057548523],"category_scores_gemma":[0.00010876183,0.00016795674,0.00012502195,0.0009235374,0.000044253942,0.00019590139,0.000049523336,0.00020458452,0.0045223236],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004167778,0.00019963112,0.017146405,0.00003560268,0.0000052236455,0.0000026088326,0.00011599868,0.000023267825,0.060606867,0.0016051084,0.9149923,0.00522532],"study_design_scores_gemma":[0.001406783,0.0002876548,0.0030551234,0.00000777088,0.000010315824,0.000015216434,0.00011846146,0.00014206347,0.026608583,0.0030832612,0.96476495,0.00049979973],"about_ca_topic_score_codex":0.000056348945,"about_ca_topic_score_gemma":0.00001553178,"teacher_disagreement_score":0.12015012,"about_ca_system_score_codex":0.000020887377,"about_ca_system_score_gemma":0.00006637092,"threshold_uncertainty_score":0.9962528},"labels":[],"label_agreement":null},{"id":"W2910047340","doi":"10.1007/s11912-019-0750-1","title":"Indoleamine Dioxygenase Inhibitors: Clinical Rationale and Current Development","year":2019,"lang":"en","type":"review","venue":"Current Oncology Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Clinical trial; Immunotherapy; Drug development; Context (archaeology); Indoleamine 2,3-dioxygenase; Drug; Oncology; Pharmacology; Immunology; Immune system; Internal medicine","score_opus":0.31269765832908053,"score_gpt":0.4751845806341543,"score_spread":0.16248692230507378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2910047340","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00083133904,0.98534334,0.000023878843,0.000029629447,0.011111208,0.00206828,0.000021458198,0.00009735511,0.00047349918],"genre_scores_gemma":[0.00006961082,0.9980519,0.00006615327,0.00007700914,0.0008065039,0.00032438512,0.00020959266,0.000054869837,0.0003400077],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.994443,0.00066806655,0.0023861986,0.0015623474,0.00044969955,0.00049066707],"domain_scores_gemma":[0.9963349,0.0010053045,0.0017022876,0.00059119484,0.00006812241,0.0002981828],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009480822,0.0006041417,0.0020586958,0.00028280268,0.00016265019,0.00005911048,0.00026479975,0.0004794279,0.00009251608],"category_scores_gemma":[0.0017014834,0.00048557788,0.00044045958,0.0003319923,0.00036608113,0.00012812414,0.00046091556,0.0012102379,0.00027449426],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000043500104,0.00071554695,0.000071072456,0.004988442,0.000020921116,0.000191549,0.00005710625,1.02428686e-7,0.0000025810812,0.000046448182,0.009506383,0.9843955],"study_design_scores_gemma":[0.00036332716,0.00010669519,0.00008762267,0.0034720558,0.00008337187,0.00075891276,0.000005735633,0.0000012774669,0.000037321603,0.0000471678,0.99460226,0.00043426987],"about_ca_topic_score_codex":3.2426433e-7,"about_ca_topic_score_gemma":0.0000026531857,"teacher_disagreement_score":0.98509586,"about_ca_system_score_codex":0.00024162153,"about_ca_system_score_gemma":0.0028995317,"threshold_uncertainty_score":0.9997596},"labels":[],"label_agreement":null},{"id":"W2910112444","doi":"10.1152/ajpcell.00448.2018","title":"Exercise training impacts skeletal muscle gene expression related to the kynurenine pathway","year":2019,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo; McMaster University; Impact","funders":"Canadian Institutes of Health Research","keywords":"Skeletal muscle; Gene; Gene expression; Kynurenine pathway; Training (meteorology); Kynurenine; Biology; Cell biology; Genetics; Endocrinology; Geography; Tryptophan","score_opus":0.011665897220576187,"score_gpt":0.2402381991957271,"score_spread":0.2285723019751509,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2910112444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99747247,0.00018220916,0.000016468955,0.0007369342,0.0008127648,0.00030831396,0.000013270777,0.000042241234,0.00041535086],"genre_scores_gemma":[0.9968429,0.00015779589,0.00039996998,0.002123652,0.00021258583,0.000010042565,0.000005165012,0.00004819933,0.00019965337],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997146,0.00062310067,0.0006454085,0.0005785323,0.00027689475,0.00073007133],"domain_scores_gemma":[0.9976151,0.00052563776,0.0009141599,0.00058235857,0.00009297854,0.00026978677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002875153,0.00035102805,0.0008356271,0.00020353649,0.00017646316,0.000019338255,0.00098999,0.00010779112,0.0003756227],"category_scores_gemma":[0.00021117128,0.00022361902,0.00035024542,0.0006781417,0.0005849072,0.00019761144,0.00020342757,0.0006921772,0.00037612772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002562163,0.00017139383,0.0000060181383,0.000010387804,0.000013068448,0.0000072747353,0.0017716987,0.002180182,0.9847635,0.000039155613,0.0009906538,0.009790449],"study_design_scores_gemma":[0.0016122534,0.0030446271,0.018817259,0.00009201849,0.000018504605,0.00006819804,0.0019942836,0.000114189424,0.96732885,0.0012785111,0.0052229497,0.00040834685],"about_ca_topic_score_codex":0.00001204751,"about_ca_topic_score_gemma":9.271875e-7,"teacher_disagreement_score":0.01881124,"about_ca_system_score_codex":0.000037932787,"about_ca_system_score_gemma":0.00015204557,"threshold_uncertainty_score":0.91189194},"labels":[],"label_agreement":null},{"id":"W2911360601","doi":"10.1016/b978-0-12-813333-0.00038-x","title":"Advances in the Neurobiology of Late-Life Depression","year":2019,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Depression (economics); Neuroscience; Late life depression; Psychology; Neurotrophic factors; Neurotrophin; Psychiatry; Medicine; Clinical psychology; Cognition; Internal medicine","score_opus":0.01959077859850176,"score_gpt":0.2540659894802908,"score_spread":0.23447521088178905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911360601","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00304644,0.0013241207,7.1374853e-7,0.00007411058,0.0003729517,0.000512912,0.000019059313,0.000022539523,0.9946272],"genre_scores_gemma":[0.16640879,0.001529416,0.000012254397,0.0037849273,0.00008252491,0.000018398028,0.0000053766976,0.00005680563,0.8281015],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986378,0.00011959565,0.00034679333,0.00045571552,0.00021564198,0.00022448783],"domain_scores_gemma":[0.99876,0.00041608553,0.00026211978,0.00051196455,0.000015222825,0.000034613564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013618525,0.00025308074,0.00037806766,0.00012277064,0.000041551233,0.000012583202,0.0006378429,0.00021394572,0.000115989365],"category_scores_gemma":[0.000111484434,0.00016455578,0.00013911366,0.000020548146,0.0002535273,0.000050282186,0.00012055755,0.0004380243,0.00012882949],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057766432,0.000019810746,0.000060783274,0.00012571126,0.0000032513767,0.000013992567,0.0003110692,0.000014337181,0.004837493,0.013438822,0.00008219777,0.98103476],"study_design_scores_gemma":[0.0003870531,0.00008519201,0.0002094715,0.00020400644,0.000008897006,0.0000061270753,0.0000121671155,0.000005000337,0.0029131174,0.009487335,0.986447,0.00023465764],"about_ca_topic_score_codex":2.3213312e-7,"about_ca_topic_score_gemma":0.000015409232,"teacher_disagreement_score":0.9863648,"about_ca_system_score_codex":0.000008692158,"about_ca_system_score_gemma":0.000077176235,"threshold_uncertainty_score":0.671039},"labels":[],"label_agreement":null},{"id":"W2911377666","doi":"10.1111/eip.12775","title":"Putative neuroprotective pharmacotherapies to target the staged progression of mental illness","year":2019,"lang":"en","type":"review","venue":"Early Intervention in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Neuroprotection; Medicine; Schizophrenia (object-oriented programming); Neuroinflammation; Pharmacology; Psychosis; Bioinformatics; Neuroscience; Psychiatry; Psychology; Internal medicine; Inflammation; Biology","score_opus":0.04219049334622837,"score_gpt":0.3883741533596313,"score_spread":0.34618366001340295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911377666","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00487444,0.98407745,0.00024762488,0.00022340531,0.0053861295,0.0045406274,0.00021002008,0.00006153535,0.00037876714],"genre_scores_gemma":[0.014333882,0.9815781,0.000387433,0.00040834103,0.00021184792,0.0012431263,0.000029951523,0.00017472402,0.0016325564],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967078,0.0012182873,0.00078551704,0.0006118415,0.00039295395,0.0002835817],"domain_scores_gemma":[0.99873114,0.00014987607,0.00069417007,0.0003398035,0.00003313449,0.000051852905],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035618572,0.00037100646,0.0007450717,0.00037312528,0.000106119085,0.00006842425,0.0007113982,0.00013004443,0.0002896226],"category_scores_gemma":[0.00011172906,0.00024709819,0.00067848817,0.0008392704,0.00014395686,0.0001671045,0.00015421258,0.000623934,0.00015617428],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016574498,0.00068989,0.000048769685,0.006154642,0.00008159212,0.000005591858,0.0037957644,0.0000063951834,0.00025272398,0.0005507325,0.000911948,0.9873362],"study_design_scores_gemma":[0.0034901171,0.0023807585,0.00060682144,0.042769805,0.00017300907,0.000051597897,0.0029376443,0.00002586095,0.0049081272,0.0019884976,0.9392143,0.00145349],"about_ca_topic_score_codex":0.000022652068,"about_ca_topic_score_gemma":0.000007592506,"teacher_disagreement_score":0.9858827,"about_ca_system_score_codex":0.000061974126,"about_ca_system_score_gemma":0.000078211066,"threshold_uncertainty_score":0.99999815},"labels":[],"label_agreement":null},{"id":"W2911912212","doi":"10.1007/s00213-019-5175-x","title":"Targeting the immune system in the treatment of bipolar disorder","year":2019,"lang":"en","type":"review","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Bipolar disorder; Adjunctive treatment; Medicine; Antidepressant; Mania; Tolerability; Minocycline; Clinical trial; Bipolar I disorder; Major depressive disorder; Mood; Psychiatry; Pharmacology; Internal medicine; Anxiety; Adverse effect","score_opus":0.05260010428938728,"score_gpt":0.3640685957087516,"score_spread":0.31146849141936434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911912212","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034526573,0.9940339,0.000004897391,0.00014790626,0.0020351342,0.0025344444,0.000043552387,0.000033575743,0.0008213291],"genre_scores_gemma":[0.0016853019,0.9971493,0.0000042848706,0.0002010592,0.00016102425,0.0005349544,0.000009430503,0.000044479268,0.00021020678],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964832,0.0015992383,0.0007531641,0.00052442355,0.00021107188,0.00042888426],"domain_scores_gemma":[0.99721,0.0017020223,0.0005034649,0.000544207,0.000013140901,0.000027146249],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036652744,0.00040372938,0.0011700046,0.00018405706,0.000121710545,0.000022575008,0.0011488841,0.0001983704,0.00012688484],"category_scores_gemma":[0.00004677158,0.00018907529,0.00049406756,0.0007407479,0.00020474604,0.000035857793,0.000043438315,0.00036222467,0.0002794956],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004914348,0.0007920979,0.000009575059,0.0058903457,0.00008509089,0.000028990153,0.00096167286,0.000014717799,0.0006554015,0.0010085804,0.00072678115,0.9897776],"study_design_scores_gemma":[0.00096701115,0.00017942832,0.0000066826337,0.00038408302,0.00019600619,0.000030686737,0.00021478375,0.0000289012,0.000068750385,0.0000072854045,0.9977406,0.00017574808],"about_ca_topic_score_codex":0.000038346767,"about_ca_topic_score_gemma":0.0000038291764,"teacher_disagreement_score":0.99701387,"about_ca_system_score_codex":0.00009831128,"about_ca_system_score_gemma":0.0000952624,"threshold_uncertainty_score":0.7710267},"labels":[],"label_agreement":null},{"id":"W2913158194","doi":"10.1177/0706743718771833","title":"Practical Aspects of Animal Models of Psychiatric Disorders","year":2019,"lang":"en","type":"editorial","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Psychiatry; Psychology; Medicine","score_opus":0.020475720985713257,"score_gpt":0.2798752668178813,"score_spread":0.259399545832168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913158194","genre_codex":"editorial","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006094314,0.0022136462,0.0001135677,0.012445488,0.95884687,0.00043849536,0.00036989377,0.0000098722,0.019467847],"genre_scores_gemma":[0.6368381,0.00068459334,0.0023422295,0.00045064028,0.35918254,0.0000034623345,0.000008644327,0.00016997798,0.000319829],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99646956,0.0003388068,0.0010954811,0.00034213808,0.0012070545,0.00054696476],"domain_scores_gemma":[0.9956243,0.0009690308,0.002065553,0.000627004,0.00027557331,0.0004385397],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00067096984,0.0003672289,0.0007514014,0.0006989445,0.00018292377,0.000065014385,0.0014508633,0.0005976262,0.00014703663],"category_scores_gemma":[0.0015638525,0.000275235,0.0005647576,0.0006849836,0.000554048,0.0002828121,0.000038101673,0.0018842088,0.00001800825],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027067616,0.00011678131,0.00013572941,0.00020725287,0.000065456734,0.0000087916,0.00019391812,0.00014979452,0.00012501334,0.059042793,0.939576,0.0001077723],"study_design_scores_gemma":[0.005854455,0.0056183147,0.00079596124,0.0010056237,0.00079939136,0.00025635856,0.0012350443,0.00037433318,0.00081445824,0.4650115,0.51662034,0.0016142124],"about_ca_topic_score_codex":0.004176934,"about_ca_topic_score_gemma":0.11061745,"teacher_disagreement_score":0.63074374,"about_ca_system_score_codex":0.000120853445,"about_ca_system_score_gemma":0.021076715,"threshold_uncertainty_score":0.99996996},"labels":[],"label_agreement":null},{"id":"W2913279861","doi":"10.1111/gbb.12561","title":"Activity‐regulated cytoskeleton‐associated protein (Arc/Arg3.1) regulates anxiety‐ and novelty‐related behaviors","year":2019,"lang":"en","type":"article","venue":"Genes Brain & Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Drug Abuse; College of Charleston; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression; McLean Foundation","keywords":"Novelty; Arc (geometry); Cytoskeleton; Cell biology; Anxiety; Psychology; Biology; Chemistry; Social psychology; Genetics; Cell; Engineering; Psychiatry","score_opus":0.013489283401333646,"score_gpt":0.24845848960609643,"score_spread":0.23496920620476278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913279861","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99493426,0.00017259989,0.0000051593343,0.00084235135,0.00039145374,0.0025022367,0.0001072276,0.0006354842,0.00040924057],"genre_scores_gemma":[0.98634803,0.000041115956,0.00013048862,0.00041837877,0.000036286365,0.00025217832,0.00004981849,0.00014499057,0.012578732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99584097,0.00038104475,0.0005572709,0.0014439225,0.0006934843,0.0010833248],"domain_scores_gemma":[0.9981529,0.00027051964,0.00034395664,0.00082260335,0.000092841394,0.00031714153],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038599415,0.0006472732,0.0006108044,0.00032384312,0.00038352775,0.00020798814,0.0005784067,0.0005533141,0.0008450929],"category_scores_gemma":[0.0003967785,0.00064669724,0.00024615185,0.0010934445,0.00042520312,0.00054540037,0.00030933297,0.000537112,0.00034641734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000736785,0.0005719345,0.00942735,0.000022774462,0.00001515636,0.000038942362,0.0004023441,0.000010899722,0.9601235,0.00021941439,0.00026693108,0.028827092],"study_design_scores_gemma":[0.0027277549,0.0002969109,0.20920603,0.00007669187,0.00006305652,0.00008540837,0.00014601076,0.00021104267,0.7837462,0.00010954009,0.0024111997,0.0009201971],"about_ca_topic_score_codex":0.00013100351,"about_ca_topic_score_gemma":0.000047787722,"teacher_disagreement_score":0.19977868,"about_ca_system_score_codex":0.00013586953,"about_ca_system_score_gemma":0.00012681862,"threshold_uncertainty_score":0.99959844},"labels":[],"label_agreement":null},{"id":"W2913452532","doi":"10.1039/c8fo02474j","title":"Suppressive effects of the supercritical-carbon dioxide fluid extract of <i>Chrysanthemum indicum</i> on chronic unpredictable mild stress-induced depressive-like behavior in mice","year":2019,"lang":"en","type":"article","venue":"Food & Function","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development","funders":"Guangzhou University of Chinese Medicine; China Postdoctoral Science Foundation","keywords":"Carbon dioxide; Chronic stress; Supercritical carbon dioxide; Traditional medicine; Chemistry; Pharmacology; Medicine; Biology; Internal medicine; Organic chemistry","score_opus":0.012490570066045798,"score_gpt":0.22791487610226804,"score_spread":0.21542430603622226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913452532","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99609977,0.00029548872,0.000008198656,0.00003801522,0.0013101675,0.0010762378,0.00005371741,0.00004537353,0.0010730185],"genre_scores_gemma":[0.9996088,0.000032945438,0.0000024202839,0.00013006505,0.00005859946,0.00009470856,0.000006211253,0.00003663318,0.00002960976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978328,0.00032130245,0.0003750244,0.0005321146,0.00052857545,0.0004101867],"domain_scores_gemma":[0.9985016,0.0007449447,0.000105694315,0.0005382686,0.000042635525,0.000066855435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000104553714,0.00024663826,0.00032635088,0.00016569739,0.00006903203,0.000015281148,0.00038458518,0.00018950937,0.00005649152],"category_scores_gemma":[0.00042039395,0.00019283967,0.00015372926,0.00046000778,0.00016745405,0.00021352414,0.000108229986,0.00044675145,0.00001275638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007696155,0.0006361899,0.006666598,0.00024097298,0.000012129244,0.000004672853,0.00015791427,0.00008107321,0.990907,0.000116671756,0.000017133643,0.00039003996],"study_design_scores_gemma":[0.0018738161,0.0063694017,0.05255526,0.0004257894,0.00005224458,0.0000038934418,0.000107899454,0.00011142341,0.9382575,0.000044816577,0.000026360885,0.00017158611],"about_ca_topic_score_codex":0.00008008871,"about_ca_topic_score_gemma":0.00007375028,"teacher_disagreement_score":0.05264948,"about_ca_system_score_codex":0.00009154039,"about_ca_system_score_gemma":0.00010207287,"threshold_uncertainty_score":0.7863773},"labels":[],"label_agreement":null},{"id":"W2914529824","doi":"10.3389/fpsyt.2019.00057","title":"Insulin Resistance as a Shared Pathogenic Mechanism Between Depression and Type 2 Diabetes","year":2019,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":161,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Institute for Translational Neuroscience; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Alzheimer Society","keywords":"Insulin resistance; Depression (economics); Type 2 diabetes; Obesity; Mood disorders; Mood; Anxiety; Diabetes mellitus; Insulin receptor; Dementia; Mechanism (biology); Bipolar disorder; Medicine; Bioinformatics; Insulin; Psychiatry; Psychology; Endocrinology; Internal medicine; Biology; Disease","score_opus":0.02660407629749932,"score_gpt":0.28668053369259305,"score_spread":0.2600764573950937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914529824","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00071941194,0.98781025,0.000052725212,0.0000632735,0.0089920275,0.0010039259,0.00016782829,0.00008886137,0.0011017019],"genre_scores_gemma":[0.00020548199,0.9948169,0.0033342263,0.00029215307,0.00021766176,0.00006797109,0.000057102494,0.00010710697,0.00090137194],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969916,0.00036606583,0.00060580566,0.0011753903,0.00031901136,0.0005421668],"domain_scores_gemma":[0.9986379,0.00015104462,0.0003764124,0.00068031857,0.000014687802,0.00013961122],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000208654,0.0005329211,0.0014337297,0.00044502533,0.00011160003,0.00009157543,0.000724938,0.00057700294,0.00004160283],"category_scores_gemma":[0.00028479326,0.00047102536,0.00025412694,0.0008616865,0.00009566694,0.00016302995,0.00020172425,0.00068468275,0.0001299134],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055169996,0.00013401968,0.0038342439,0.018465763,0.00008008164,0.000014918962,0.0001249846,1.7883085e-7,0.000031430052,0.0011643238,0.067260504,0.9088344],"study_design_scores_gemma":[0.0008306063,0.0000854258,0.0004654858,0.011561262,0.00020682007,0.000004038433,0.000046688394,0.0000066105517,0.00002401838,0.021722006,0.9641522,0.0008948461],"about_ca_topic_score_codex":0.0000015641594,"about_ca_topic_score_gemma":0.0000053612366,"teacher_disagreement_score":0.90793955,"about_ca_system_score_codex":0.00007145394,"about_ca_system_score_gemma":0.00033856602,"threshold_uncertainty_score":0.99977416},"labels":[],"label_agreement":null},{"id":"W2914828693","doi":"10.1016/j.jpsychires.2019.02.005","title":"A clinical model for identifying an inflammatory phenotype in mood disorders","year":2019,"lang":"en","type":"review","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Stanley Medical Research Institute","keywords":"Rheumatoid arthritis; Inflammation; Medicine; Mood disorders; Depression (economics); Mood; Proinflammatory cytokine; Obesity; Diabetes mellitus; Metabolic syndrome; Bioinformatics; Immunology; Internal medicine; Psychiatry; Clinical psychology; Endocrinology; Anxiety; Biology","score_opus":0.41413698992936054,"score_gpt":0.5468793506377916,"score_spread":0.13274236070843104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914828693","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00095061323,0.9928407,0.0012426693,0.000157439,0.0017988712,0.0019047306,0.00002072833,0.000015425745,0.0010688183],"genre_scores_gemma":[0.001050245,0.9961928,0.0014263045,0.000036237605,0.0007540256,0.00004335617,0.0000026045286,0.00010040195,0.00039401205],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99279964,0.0019051314,0.0023869553,0.00069629814,0.0013954366,0.00081653625],"domain_scores_gemma":[0.99520147,0.0024931305,0.001144891,0.0006398059,0.0002179563,0.00030277538],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0072689583,0.00034745713,0.0016489993,0.0023300417,0.00016707183,0.00019700614,0.0016446556,0.00050850096,0.000027068912],"category_scores_gemma":[0.0026103097,0.00027140477,0.0012080524,0.0016972538,0.00019633443,0.00041189816,0.00018576322,0.0029540437,0.000072561576],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022183052,0.00086644443,0.00024899494,0.014818133,0.00004975658,0.000015149948,0.00022634753,0.00020272109,0.0000074326354,0.0017122268,0.003724578,0.9779064],"study_design_scores_gemma":[0.0077802707,0.002594496,0.00041057557,0.008711659,0.00039557702,0.0001244263,0.00041803723,0.015653081,0.0000019023956,0.044380978,0.91803044,0.0014985647],"about_ca_topic_score_codex":0.000004814535,"about_ca_topic_score_gemma":0.00007479959,"teacher_disagreement_score":0.9764078,"about_ca_system_score_codex":0.00016157514,"about_ca_system_score_gemma":0.0025126257,"threshold_uncertainty_score":0.99997383},"labels":[],"label_agreement":null},{"id":"W2914913787","doi":"10.3389/fnins.2019.00098","title":"Exploring the Potential Antidepressant Mechanisms of TNFα Antagonists","year":2019,"lang":"en","type":"review","venue":"Frontiers in Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antidepressant; Tumor necrosis factor alpha; Inflammation; Depression (economics); Microglia; Cytokine; Medicine; Proinflammatory cytokine; Sickness behavior; Neuroscience; Animal models of depression; Immune system; Neuroinflammation; Pharmacology; Immunology; Psychology; Hippocampus","score_opus":0.12646373680783002,"score_gpt":0.3061849621998564,"score_spread":0.1797212253920264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914913787","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027976496,0.9625235,0.012589992,0.000088383844,0.02136011,0.0021501796,0.00012453349,0.000114165814,0.00076933985],"genre_scores_gemma":[0.003421053,0.99545324,0.00036259016,0.00026401825,0.00005223336,0.00010060098,0.0000020327848,0.00006304237,0.0002811761],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99572456,0.0005337067,0.0008021012,0.0013341232,0.00085991283,0.00074562675],"domain_scores_gemma":[0.9980359,0.00021599192,0.0005610129,0.0010726296,0.000019424355,0.000095038486],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004448259,0.0005106457,0.0013398209,0.0005317755,0.00021638395,0.00013785945,0.0028089087,0.00012674562,0.000007053822],"category_scores_gemma":[0.00070545456,0.00035055433,0.00046688275,0.0018821835,0.0007761587,0.0005173087,0.0005409389,0.0007075614,0.000021198131],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025445488,0.00023593412,0.000014944035,0.006072165,0.00000687751,0.00022199667,0.0001564245,0.00015466049,0.009239756,0.00434665,0.0018140516,0.9777111],"study_design_scores_gemma":[0.00051877514,0.00019313012,0.00018279675,0.004230721,0.0001267855,0.00019111922,0.00014438183,0.0010738235,0.007345084,0.001820916,0.98306304,0.001109417],"about_ca_topic_score_codex":0.000010002842,"about_ca_topic_score_gemma":7.716801e-7,"teacher_disagreement_score":0.981249,"about_ca_system_score_codex":0.00006031426,"about_ca_system_score_gemma":0.0002730952,"threshold_uncertainty_score":0.9998946},"labels":[],"label_agreement":null},{"id":"W2914973600","doi":"10.1016/j.brs.2018.12.427","title":"Oxidized phosphatidylcholines as a predictive factor of treatment response to repetitive transcranial magnetic stimulation in major depressive disorder","year":2019,"lang":"en","type":"article","venue":"Brain stimulation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"","keywords":"Transcranial magnetic stimulation; Biomarker; Oxidative stress; Major depressive disorder; Depression (economics); Stimulation; Medicine; Neuroscience; Internal medicine; Psychology; Psychiatry; Mood; Chemistry; Biochemistry","score_opus":0.015050466104979428,"score_gpt":0.28177373319487836,"score_spread":0.2667232670898989,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914973600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946283,0.00005460627,0.0015552687,0.0005341675,0.00014371016,0.0025032964,0.00012426813,0.000073097064,0.00038326872],"genre_scores_gemma":[0.9983613,0.00000764007,0.00026896887,0.00029502137,0.000027023394,0.00009783367,0.00001990546,0.00003355068,0.00088874606],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99784124,0.00044381173,0.00045522678,0.00062806567,0.00034551337,0.00028615588],"domain_scores_gemma":[0.99777967,0.001583872,0.00016184492,0.00030281258,0.000078515666,0.00009328642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014685487,0.00025755668,0.00032621445,0.0003371088,0.000063438805,0.000029286224,0.00014637975,0.0001224118,0.0005177147],"category_scores_gemma":[0.0015899499,0.0002395452,0.0001059958,0.00061233295,0.00006493703,0.00028167176,0.000027044356,0.00008597624,0.000092428025],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01777905,0.00038228513,0.015075614,0.0000231628,0.0000092139935,0.0000059492363,0.0058553875,0.058316994,0.8974484,0.00019208243,0.000011371626,0.004900456],"study_design_scores_gemma":[0.018361738,0.0044991747,0.73951966,0.00013222637,0.000024141762,0.0000036718952,0.00033209112,0.035630006,0.19994186,0.00068511785,0.00043063195,0.00043967064],"about_ca_topic_score_codex":0.0002134794,"about_ca_topic_score_gemma":0.000082915976,"teacher_disagreement_score":0.72444403,"about_ca_system_score_codex":0.00016778277,"about_ca_system_score_gemma":0.00014326473,"threshold_uncertainty_score":0.976837},"labels":[],"label_agreement":null},{"id":"W2915906110","doi":"10.1016/j.bbi.2019.02.029","title":"Longitudinal changes of inflammatory biomarkers moderate the relationship between recent stressful life events and prospective symptoms of depression in a diverse sample of urban adolescents","year":2019,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Social Sciences and Humanities Research Council of Canada; National Science Foundation","keywords":"Stressor; Depression (economics); Depressive symptoms; Medicine; Longitudinal study; Prospective cohort study; Internal medicine; Clinical psychology; Psychiatry; Anxiety; Pathology","score_opus":0.04679806201434873,"score_gpt":0.2860789881166095,"score_spread":0.23928092610226076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2915906110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990072,0.00014553401,0.0000059873787,0.000038918413,0.000038476264,0.00063331285,0.000104653904,0.0000075552566,0.000018307937],"genre_scores_gemma":[0.9998851,0.000046818495,0.0000102256045,0.000014615599,0.000004295443,0.000015454672,0.000006150727,0.000008336672,0.000009039179],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99890345,0.0003078778,0.000250707,0.00020096105,0.00019708628,0.00013993628],"domain_scores_gemma":[0.9988735,0.0005703282,0.00021995105,0.000247018,0.000041115378,0.000048116734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002656772,0.0001169124,0.0002143597,0.00012415992,0.00008930745,0.0000076364095,0.00016532307,0.00007186946,0.000011229273],"category_scores_gemma":[0.0006937336,0.00009163973,0.000031034386,0.00022763056,0.00025041736,0.00012669557,0.00017950308,0.00017156094,3.533059e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001993119,0.00016285489,0.9762503,0.00009771432,0.0000057807606,3.4148218e-7,0.0012419432,0.0000017938684,0.020276148,0.00004421748,0.0000044132507,0.001715161],"study_design_scores_gemma":[0.0012316137,0.0001223061,0.9726709,0.00023412667,0.000018146511,6.22379e-7,0.0006606147,0.000015530582,0.024841392,0.00011733745,0.000002088804,0.0000852917],"about_ca_topic_score_codex":0.00026085318,"about_ca_topic_score_gemma":0.00006568922,"teacher_disagreement_score":0.0045652445,"about_ca_system_score_codex":0.000016253127,"about_ca_system_score_gemma":0.000032110493,"threshold_uncertainty_score":0.373696},"labels":[],"label_agreement":null},{"id":"W2916129467","doi":"10.1503/jpn.170201","title":"GABA levels and TSPO expression in people at clinical high risk for psychosis and healthy volunteers: a PET-MRS study","year":2019,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health","keywords":"Translocator protein; GABAergic; Psychosis; Prefrontal cortex; Internal medicine; Positron emission tomography; Psychology; Schizophrenia (object-oriented programming); gamma-Aminobutyric acid; Dorsolateral prefrontal cortex; Endocrinology; Neuroscience; Pathophysiology; Medicine; Psychiatry; Inflammation; Receptor; Neuroinflammation","score_opus":0.039906430041521376,"score_gpt":0.3447128236467264,"score_spread":0.304806393605205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916129467","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950699,0.0002991288,0.00009380103,0.0016690951,0.002301042,0.00051822583,0.000022041446,0.0000093830895,0.000017355189],"genre_scores_gemma":[0.9965322,0.00096319214,0.0006332638,0.0016810085,0.00008930578,0.0000054272496,6.390582e-8,0.000013218452,0.00008232887],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99776506,0.00032169474,0.000642322,0.000618846,0.00033482665,0.0003172504],"domain_scores_gemma":[0.9985497,0.0005238635,0.00045041952,0.00019704158,0.00002965317,0.00024932998],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010414963,0.00017848967,0.0003753883,0.00019834761,0.00027951616,0.00009498546,0.0002674009,0.000054127402,0.000010617828],"category_scores_gemma":[0.00057918724,0.0001385017,0.0000748879,0.00033765225,0.00021417715,0.00045695188,0.000121220975,0.0003757523,0.0000014759354],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009111984,0.0007143837,0.96969557,0.000056723256,0.0000016165283,0.0000075521452,0.00053401483,0.000014451022,0.026645645,0.00008517387,0.00040989058,0.00092375773],"study_design_scores_gemma":[0.0045406246,0.004219748,0.98782665,0.000077022276,0.000011890008,0.00019977469,0.0007478038,0.00049071875,0.00061982207,0.00062774704,0.0004634015,0.00017481335],"about_ca_topic_score_codex":0.000014803934,"about_ca_topic_score_gemma":0.00020432746,"teacher_disagreement_score":0.026025824,"about_ca_system_score_codex":0.000014468481,"about_ca_system_score_gemma":0.0000763784,"threshold_uncertainty_score":0.5647935},"labels":[],"label_agreement":null},{"id":"W2917718993","doi":"10.1177/0706743719828970","title":"Biomarqueurs de L’inflammation et Dépression du Post-Partum: Une Revue Systématique De la Littérature","year":2019,"lang":"fr","type":"review","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Inflammation; Gynecology; Tumor necrosis factor alpha; PsycINFO; Internal medicine; MEDLINE","score_opus":0.01778339963519365,"score_gpt":0.2806531105521338,"score_spread":0.26286971091694017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2917718993","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005625437,0.8431518,0.00018414034,0.13608243,0.007979855,0.00088366313,0.0002068544,0.000021025393,0.005864785],"genre_scores_gemma":[0.015064936,0.9704809,0.0019046743,0.006692415,0.0039196666,0.000018615245,0.00003364905,0.00019567939,0.0016894321],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99378777,0.0036295708,0.0011019795,0.00035086507,0.00034633523,0.0007835015],"domain_scores_gemma":[0.99574655,0.00074072427,0.0017356875,0.0006283938,0.00022311298,0.0009255259],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0028853887,0.000540197,0.0009262122,0.00056882424,0.0005648661,0.0005060483,0.0015564032,0.00088686857,0.00019123801],"category_scores_gemma":[0.001257022,0.00039433574,0.0007430528,0.0010555359,0.0004708913,0.0003260536,0.000039756447,0.002337524,0.00013429274],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025346936,0.00029559474,0.003874034,0.048966795,0.0006479228,0.0017424802,0.011292532,0.0017044358,0.002308062,0.56942946,0.1698041,0.18968113],"study_design_scores_gemma":[0.0007841584,0.00031236355,0.0031161574,0.03797229,0.000580614,0.013028125,0.00063006143,0.00012600338,0.00010890005,0.0134112965,0.92922014,0.00070989336],"about_ca_topic_score_codex":0.0057977643,"about_ca_topic_score_gemma":0.11009271,"teacher_disagreement_score":0.75941604,"about_ca_system_score_codex":0.0006983354,"about_ca_system_score_gemma":0.020334572,"threshold_uncertainty_score":0.9999641},"labels":[],"label_agreement":null},{"id":"W2917817971","doi":"10.5114/aoms.2019.83146","title":"Immune to happiness – inflammatory process indicators and depressive personality traits","year":2019,"lang":"en","type":"article","venue":"Archives of Medical Science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Uniwersytet Łódzki","keywords":"Medicine; Minnesota Multiphasic Personality Inventory; Myeloperoxidase; Oxidative stress; Neuroticism; Immune system; Inflammation; Superoxide dismutase; Depression (economics); Personality; Immunology; Internal medicine; Clinical psychology; Psychology","score_opus":0.01150651532215146,"score_gpt":0.2788680948703659,"score_spread":0.26736157954821443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2917817971","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99234176,0.000055325632,0.00014014366,0.0016712773,0.000084579435,0.00025672207,0.000004753937,0.00002885254,0.0054166014],"genre_scores_gemma":[0.99915344,0.000024128967,0.00006654938,0.00066429994,0.000017276756,0.000010978462,1.9755007e-7,0.0000054038437,0.000057751604],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99751645,0.000062317995,0.0002145627,0.0005140359,0.0013470781,0.00034553776],"domain_scores_gemma":[0.9988752,0.00040006355,0.00009045885,0.00017610146,0.000013208072,0.00044496576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042265496,0.00010822149,0.0001728695,0.00021804655,0.00013429162,0.000030793442,0.0011675435,0.000040118826,0.0001324055],"category_scores_gemma":[0.0023167701,0.00008359995,0.00003447989,0.0007250143,0.0022981334,0.00021118802,0.00033590745,0.00017517923,0.000016952448],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006956373,0.000143207,0.02383804,0.00019903225,0.0000035999822,0.000013359718,0.009627466,0.0000143285315,0.8112765,0.01146141,0.0000151613785,0.14333831],"study_design_scores_gemma":[0.00068189576,0.00009464593,0.75456256,0.00017176551,0.0000019360568,0.000016062735,0.00044962057,0.0008461822,0.24082129,0.0016724181,0.0004934034,0.00018822556],"about_ca_topic_score_codex":0.000015844073,"about_ca_topic_score_gemma":0.000004979482,"teacher_disagreement_score":0.7307245,"about_ca_system_score_codex":0.00000543342,"about_ca_system_score_gemma":0.00032495524,"threshold_uncertainty_score":0.8467568},"labels":[],"label_agreement":null},{"id":"W2918491080","doi":"","title":"Immunomodulatory effects of antipsychotic treatment on gene expression in first-episode psychosis","year":2019,"lang":"en","type":"article","venue":"STM:n Hallinnonalan avoin julkaisuarkisto (Julkari)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Risperidone; Olanzapine; Antipsychotic; Quetiapine; Psychosis; Immune system; Atypical antipsychotic; Schizophrenia (object-oriented programming); Medicine; TLR2; Internal medicine; Innate immune system; Immunology; Pharmacology; Psychology; Psychiatry","score_opus":0.015306499330311384,"score_gpt":0.2587234468195647,"score_spread":0.24341694748925333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2918491080","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98935795,0.0008484478,0.00011797552,0.00027901042,0.0014013103,0.0015993755,0.00004690836,0.00015133826,0.006197704],"genre_scores_gemma":[0.9960878,0.00059104676,0.00042040797,0.0007066237,0.00009752195,0.00015346613,0.00002693047,0.00011125014,0.0018049569],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956323,0.0003860874,0.00089078286,0.0014375969,0.0007880853,0.00086516177],"domain_scores_gemma":[0.99690044,0.001098594,0.00040270633,0.0013413306,0.000050715236,0.00020623194],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028362902,0.00070066657,0.0008752517,0.0006200903,0.00016884203,0.00005674019,0.0007839767,0.00029528688,0.00032190882],"category_scores_gemma":[0.00018584989,0.00062210043,0.00037683558,0.0008109371,0.00023961395,0.00023176667,0.00009739538,0.00044907408,0.0008188519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014597125,0.0038066017,0.04083597,0.0005124173,0.000056169065,0.00013928924,0.0010377462,0.0008637846,0.94385356,0.0016336195,0.0014040259,0.004397113],"study_design_scores_gemma":[0.0075346944,0.0021631105,0.104287714,0.0008320724,0.000025375051,0.000021852584,0.000054194894,0.0006320102,0.87114936,0.0012672526,0.0110991,0.00093328493],"about_ca_topic_score_codex":0.00019066568,"about_ca_topic_score_gemma":0.00016981272,"teacher_disagreement_score":0.07270421,"about_ca_system_score_codex":0.00029810992,"about_ca_system_score_gemma":0.00006456306,"threshold_uncertainty_score":0.9999591},"labels":[],"label_agreement":null},{"id":"W2920456105","doi":"10.1016/j.neuropharm.2019.02.034","title":"Prenatal treatment with methylazoxymethanol acetate as a neurodevelopmental disruption model of schizophrenia in mice","year":2019,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Ministry of Education, Culture, Sports, Science and Technology","keywords":"Schizophrenia (object-oriented programming); Psychology; Prenatal exposure; Neuroscience; Neurodevelopmental disorder; Pregnancy; Psychiatry; Biology; Gestation; Genetics; Autism","score_opus":0.022633105229522908,"score_gpt":0.2822677138406972,"score_spread":0.2596346086111743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2920456105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972654,0.000027703845,0.000025546875,0.00020864398,0.00027093265,0.0007148754,0.000022755676,0.000061857485,0.0014022868],"genre_scores_gemma":[0.99775374,0.00013261358,0.00031607496,0.0009910039,0.000013194807,0.00006148569,0.0000030713716,0.00003766003,0.00069118215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982242,0.00026265185,0.0002832785,0.0006315089,0.00021501601,0.00038332786],"domain_scores_gemma":[0.9993422,0.00024191405,0.00013809666,0.00017378038,0.000018974095,0.00008504603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000056174966,0.0002472886,0.0003093004,0.0002446851,0.000036448342,0.000012149153,0.00026816357,0.00006269322,0.00018109009],"category_scores_gemma":[0.000044198907,0.00020281112,0.000060261787,0.00039222135,0.00013626809,0.00019443409,0.000091441994,0.00020231216,0.00016826077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016744126,0.00034211567,0.00047535272,0.00003368618,0.000009332247,0.000089058994,0.00039437923,0.002857095,0.9902917,0.00018782885,0.000008157429,0.00363689],"study_design_scores_gemma":[0.006198026,0.0010418263,0.0023647537,0.000012632215,0.000015253708,0.00006506484,0.000030829222,0.011241498,0.97862834,0.00008801031,0.00010989506,0.00020386558],"about_ca_topic_score_codex":0.000026084821,"about_ca_topic_score_gemma":0.00001404593,"teacher_disagreement_score":0.011663347,"about_ca_system_score_codex":0.00006580754,"about_ca_system_score_gemma":0.00017202448,"threshold_uncertainty_score":0.8270397},"labels":[],"label_agreement":null},{"id":"W2921720745","doi":"10.1111/dmcn.14209","title":"The importance of maternal immunity in psychiatry and neurodevelopment","year":2019,"lang":"en","type":"letter","venue":"Developmental Medicine & Child Neurology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Immunity; Psychiatry; Medicine; Psychology; Child and adolescent psychiatry; Immunology; Immune system","score_opus":0.013377988756881629,"score_gpt":0.23500534943763263,"score_spread":0.221627360680751,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921720745","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45018113,0.00041019623,6.555684e-7,0.5432281,0.0022934822,0.00047657092,0.000010936111,0.000029869227,0.0033690804],"genre_scores_gemma":[0.13906024,0.0011667307,0.000042144864,0.8588164,0.0003782467,0.00003815522,0.000026153488,0.00006669456,0.0004052413],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.99663705,0.00041429527,0.00091890595,0.0008385749,0.00052282755,0.0006683619],"domain_scores_gemma":[0.9982066,0.00083279086,0.00045871313,0.0004282795,0.00002052832,0.00005309915],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00031344075,0.00048553073,0.00065540074,0.0003101932,0.00020885353,0.00001824346,0.00089194905,0.0003979478,0.00011681656],"category_scores_gemma":[0.00044863965,0.00033985838,0.00005579032,0.00035337693,0.0009276508,0.00006781306,0.00041306257,0.0024804133,0.00002885105],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052059785,0.00013753262,0.24054387,0.00055995304,0.000048350506,0.00093776337,0.0008073148,0.0000019022456,0.0027586021,0.00060814054,0.7453108,0.0077651776],"study_design_scores_gemma":[0.0019242693,0.00038793843,0.5213541,0.00019944548,0.000008581564,0.0012034973,0.000034537432,0.0000063610582,0.0012795734,0.0006594342,0.47253504,0.00040723284],"about_ca_topic_score_codex":0.00003900968,"about_ca_topic_score_gemma":0.00011698651,"teacher_disagreement_score":0.31558833,"about_ca_system_score_codex":0.000032804062,"about_ca_system_score_gemma":0.00022107751,"threshold_uncertainty_score":0.99990535},"labels":[],"label_agreement":null},{"id":"W2921811730","doi":"10.1093/jcag/gwz006.031","title":"A32 THE ROLE OF GUT MICROBIOTA AND TRACE AMINES IN A MURINE MODEL OF GENERALIZED ANXIETY DISORDER","year":2019,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"","keywords":"Gut–brain axis; Gut flora; Generalized anxiety disorder; Anxiety; Dopamine; Immune system; Serotonin; Major depressive disorder; Biology; Endocrinology; Internal medicine; Immunology; Psychology; Medicine; Psychiatry; Amygdala; Receptor","score_opus":0.006175691554847217,"score_gpt":0.19863699965848902,"score_spread":0.19246130810364181,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921811730","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99383646,0.000060206985,0.0000066016223,0.0057366043,0.000107130974,0.0001232981,0.00004682928,7.709424e-7,0.00008210241],"genre_scores_gemma":[0.99899465,0.00008798913,0.000075525604,0.00061441615,0.000011676929,7.137694e-7,3.1733862e-7,0.0000063552197,0.00020837832],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988932,0.00025704925,0.00041283295,0.00008661816,0.00015740911,0.00019287424],"domain_scores_gemma":[0.99876446,0.00008012866,0.00088704325,0.00012807894,0.00009096203,0.00004931697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036422256,0.000075273034,0.00027053646,0.00014521988,0.000030198371,0.0000064175,0.00030854443,0.000065788816,0.000017199689],"category_scores_gemma":[0.00024096266,0.000050340244,0.000108917586,0.00012157563,0.00009300923,0.00006315977,0.00003426268,0.0001651893,3.0469457e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000133903,0.00004907917,0.610905,0.000010789426,0.00002033902,2.3693266e-7,0.00041565808,0.0024900131,0.3853981,0.00016071532,0.00027989768,0.00013629023],"study_design_scores_gemma":[0.0053943237,0.0005121513,0.9589411,0.00006138205,0.000042239524,0.000047347523,0.0004280334,0.008700566,0.022899736,0.0014091006,0.0014675923,0.000096409465],"about_ca_topic_score_codex":0.0023263046,"about_ca_topic_score_gemma":0.14582406,"teacher_disagreement_score":0.36249834,"about_ca_system_score_codex":0.0001114073,"about_ca_system_score_gemma":0.00010482647,"threshold_uncertainty_score":0.8697624},"labels":[],"label_agreement":null},{"id":"W2921835779","doi":"10.1021/acs.analchem.8b05884","title":"Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma—Application to Clinical and Epidemiology Cohorts","year":2019,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"NIHR Imperial Biomedical Research Centre; National Institutes of Health; Alzheimer Society; National Institute for Health and Care Research; UK Dementia Research Institute; Medical Research Council","keywords":"Chromatography; Chemistry; Analyte; Tandem mass spectrometry; Selected reaction monitoring; Electrospray ionization; Kynurenine; Solid phase extraction; Protein precipitation; Mass spectrometry; Liquid chromatography–mass spectrometry; Electrospray; Tryptophan; Biochemistry; Amino acid","score_opus":0.016067791786440255,"score_gpt":0.29237375034325547,"score_spread":0.2763059585568152,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921835779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972942,0.00020888695,0.0013263212,0.0006878776,0.000011872364,0.00027701334,0.000010786774,0.000015294403,0.00016778747],"genre_scores_gemma":[0.9978756,0.0010613549,0.00078214216,0.00021889566,0.000013558833,0.0000076037995,0.000010385271,0.000010729826,0.000019746047],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984199,0.00010438234,0.0005806426,0.0005221803,0.00012648573,0.00024640813],"domain_scores_gemma":[0.99884444,0.0005058686,0.0002493289,0.00022190005,0.00003546984,0.00014298467],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006027213,0.00014076693,0.0005087643,0.00010403962,0.00003325105,0.00000868416,0.00009329696,0.00012046595,0.000012839741],"category_scores_gemma":[0.00039029008,0.00012271156,0.00003083798,0.0006475963,0.00035739495,0.00008846218,0.00002488341,0.00015922767,7.994208e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027269346,0.000065473745,0.5569868,0.0002052699,0.000013502555,2.0281321e-7,0.000019122517,0.000021928028,0.4411478,0.0008254703,0.000010098569,0.0004316177],"study_design_scores_gemma":[0.00064542546,0.000420167,0.60444295,0.000052878473,0.000013132009,0.00000972007,0.000043741587,0.0047853254,0.38924292,0.0001831497,0.000034803976,0.00012577423],"about_ca_topic_score_codex":0.0000103984885,"about_ca_topic_score_gemma":0.0000043058703,"teacher_disagreement_score":0.051904906,"about_ca_system_score_codex":0.000012811566,"about_ca_system_score_gemma":0.00004833685,"threshold_uncertainty_score":0.5004032},"labels":[],"label_agreement":null},{"id":"W2922174715","doi":"10.3389/fphar.2019.00190","title":"Patterns of Membrane Protein Clustering in Peripheral Lymphocytes as Predictors of Therapeutic Outcomes in Major Depressive Disorder","year":2019,"lang":"en","type":"review","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Xunta de Galicia","keywords":"Antidepressant; Depression (economics); Major depressive disorder; Peripheral; Medicine; Serotonin transporter; Cluster analysis; Serotonin; Bioinformatics; Psychology; Pharmacology; Receptor; Internal medicine; Psychiatry; Biology; Anxiety; Computer science; Cognition","score_opus":0.02777964687692532,"score_gpt":0.3219081961537455,"score_spread":0.2941285492768202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922174715","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13336195,0.8593708,0.00012874544,0.00004405279,0.002710366,0.0040429686,0.00012503803,0.000029332094,0.00018672513],"genre_scores_gemma":[0.100304365,0.898099,0.000091251146,0.0002085681,0.000038305127,0.00071445544,0.000014490576,0.000095057614,0.0004344921],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962602,0.0009586873,0.0011815877,0.00073898537,0.00027114345,0.0005893559],"domain_scores_gemma":[0.9986635,0.00032071213,0.0006377989,0.00030463276,0.000016879383,0.000056504614],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021275638,0.0005173488,0.0024554022,0.0009827247,0.000020160409,0.000010070109,0.00089754496,0.00040739003,0.00020380798],"category_scores_gemma":[0.00012239472,0.0004490559,0.000310761,0.0006114768,0.00020472839,0.00014670359,0.00024414153,0.0005570096,0.000004765837],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011161726,0.0027560336,0.2640685,0.06544548,0.00063115545,0.00037729953,0.0034201373,0.001287127,0.009498884,0.000071380564,0.00024942303,0.6510784],"study_design_scores_gemma":[0.13500255,0.0038682327,0.037636906,0.060936004,0.003139102,0.0002384568,0.0046505043,0.008767764,0.108422086,0.0014428451,0.624442,0.011453544],"about_ca_topic_score_codex":0.00020957272,"about_ca_topic_score_gemma":0.00013564674,"teacher_disagreement_score":0.63962483,"about_ca_system_score_codex":0.00030089976,"about_ca_system_score_gemma":0.00035452185,"threshold_uncertainty_score":0.9997961},"labels":[],"label_agreement":null},{"id":"W2924222392","doi":"10.3389/fpsyt.2019.00151","title":"Understanding the Relation Between Early-Life Adversity and Depression Symptoms: The Moderating Role of Sex and an Interleukin-1β Gene Variant","year":2019,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; University of Ottawa; Royal Ottawa Mental Health Centre","funders":"Canadian Institutes of Health Research","keywords":"SNP; Single-nucleotide polymorphism; Depression (economics); Context (archaeology); Psychology; Clinical psychology; Depressive symptoms; Cytokine; Genotype; Psychiatry; Medicine; Internal medicine; Gene; Genetics; Biology; Anxiety","score_opus":0.01924835557557718,"score_gpt":0.23493550924540846,"score_spread":0.21568715366983127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2924222392","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9873088,0.00043156047,0.010144519,0.00025238108,0.00082473777,0.00026681644,0.000005962678,0.000019565397,0.0007456833],"genre_scores_gemma":[0.99885136,0.000030286894,0.0008090589,0.00021407317,0.00006250896,0.0000023142325,0.0000012978787,0.000011106908,0.00001801935],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99900275,0.00019558975,0.00018170653,0.00029681085,0.0001617195,0.00016140092],"domain_scores_gemma":[0.99948496,0.0001096078,0.00011354892,0.00023752266,0.000006207362,0.000048129248],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025392647,0.0001067276,0.00013913034,0.000075403594,0.00022520556,0.000050372335,0.00019684936,0.000077349905,0.0000039134948],"category_scores_gemma":[0.00005231491,0.00007125102,0.00002610337,0.00014835247,0.00013487451,0.00026525013,0.0000913959,0.00021140378,5.866154e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056932637,0.000023835808,0.9881573,0.000017376522,0.000012041351,3.2618644e-7,0.0050727236,0.00025462735,0.0031895344,0.001820168,0.00017737402,0.0012177615],"study_design_scores_gemma":[0.0017775922,0.00015581511,0.86586916,0.000120291035,0.00003155856,0.000006928923,0.027239777,0.04462596,0.0020944674,0.05776565,0.00003239651,0.00028039803],"about_ca_topic_score_codex":0.00002609146,"about_ca_topic_score_gemma":0.000011903548,"teacher_disagreement_score":0.12228814,"about_ca_system_score_codex":0.000028997445,"about_ca_system_score_gemma":0.000031677828,"threshold_uncertainty_score":0.29055324},"labels":[],"label_agreement":null},{"id":"W2925007637","doi":"10.1016/j.euroneuro.2017.08.292","title":"UBIQUITINATED PROTEINS ARE ELEVATED IN THE BLOOD AND BRAIN OF INDIVIDUALS WITH SCHIZOPHRENIA","year":2019,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Schizophrenia (object-oriented programming); Ubiquitin; Clozapine; Internal medicine; Medicine; Endocrinology; Biology; Psychiatry; Gene; Genetics","score_opus":0.014125844476702265,"score_gpt":0.25735313498421336,"score_spread":0.2432272905075111,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2925007637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915234,0.00004484244,0.0000020624868,0.0018393182,0.00014008427,0.0010931285,0.0000181434,0.000119822034,0.0052192216],"genre_scores_gemma":[0.9913829,0.000038942464,0.000047579473,0.008181528,0.000038241426,0.00001970827,0.0000017537639,0.0000716876,0.00021766864],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9963709,0.0020312923,0.00034256393,0.00060916296,0.00026078994,0.00038529126],"domain_scores_gemma":[0.9988078,0.0004802727,0.0002694451,0.00034380986,0.0000297466,0.000068934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047040422,0.00023868462,0.00026102067,0.00022445596,0.00005890341,0.000039932955,0.00063853903,0.00003959326,0.00011454261],"category_scores_gemma":[0.0002194574,0.00016577622,0.000037021273,0.00083391776,0.0003084415,0.00011461574,0.000115800896,0.0004736676,0.00007317008],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045218685,0.00034610007,0.007111853,0.000042575324,0.000011746145,0.00032942934,0.0005446383,0.000017877604,0.98954093,0.00050491816,0.0005333804,0.00056436553],"study_design_scores_gemma":[0.020926123,0.0022207082,0.8523659,0.000106654865,0.00004307934,0.00046106594,0.00031077096,0.000066706285,0.11259792,0.00014774471,0.010172858,0.00058046845],"about_ca_topic_score_codex":0.0000032123335,"about_ca_topic_score_gemma":0.0000036654415,"teacher_disagreement_score":0.876943,"about_ca_system_score_codex":0.0000041032395,"about_ca_system_score_gemma":0.00002637239,"threshold_uncertainty_score":0.67601585},"labels":[],"label_agreement":null},{"id":"W2926139416","doi":"10.1016/j.biopsych.2019.02.023","title":"Role of Monocyte-Derived MicroRNA106b∼25 in Resilience to Social Stress","year":2019,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Center for Complementary and Integrative Health; National Institute of Mental Health; National Cancer Institute; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Brain and Behavior Research Foundation","keywords":"Inflammation; Immune system; Immunology; microRNA; Phenotype; Monocyte; Bone marrow; Social defeat; Biology; Gene; Genetics; Neuroscience","score_opus":0.02237448370442943,"score_gpt":0.2724449161099963,"score_spread":0.2500704324055669,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2926139416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99370295,0.00013114345,0.000008221643,0.00078234414,0.0003246755,0.00029363562,0.00003434805,0.000042942553,0.0046797567],"genre_scores_gemma":[0.9981557,0.000016705355,0.00037205036,0.0013025854,0.00005856656,0.000009566945,0.0000014977032,0.0000071615673,0.00007614118],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987486,0.00011698821,0.00024544663,0.0004581869,0.00012484094,0.00030595274],"domain_scores_gemma":[0.9995798,0.000085797816,0.0000767942,0.00018354775,0.000011245794,0.00006279789],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000071884875,0.00013026648,0.000211113,0.00008018438,0.000044003715,0.000012182935,0.0004487637,0.00013996809,0.0001668669],"category_scores_gemma":[0.00012708653,0.000101079575,0.000080399426,0.0003601311,0.00012283772,0.00004543703,0.00011643403,0.00014559198,0.00020859647],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015337238,0.00021670364,0.09591212,0.000010772578,0.0000011324497,6.5708116e-7,0.00015535847,0.000014564323,0.8970376,0.00473704,0.0002727435,0.0014879027],"study_design_scores_gemma":[0.0007872202,0.0003364337,0.8379646,0.000030467498,0.0000010004176,0.0000013367693,0.0009875202,0.000024380142,0.15294197,0.0052012596,0.0014735155,0.0002502876],"about_ca_topic_score_codex":0.000022341428,"about_ca_topic_score_gemma":0.0000381703,"teacher_disagreement_score":0.7440957,"about_ca_system_score_codex":0.000015509315,"about_ca_system_score_gemma":0.00003728425,"threshold_uncertainty_score":0.41219056},"labels":[],"label_agreement":null},{"id":"W2926187639","doi":"10.1016/j.jpsychires.2019.03.030","title":"Interplay between pro-inflammatory cytokines, childhood trauma, and executive function in depressed adolescents","year":2019,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Mental Health; American Psychological Foundation","keywords":"Depression (economics); Medicine; Major depressive disorder; Psychology; Internal medicine; Psychiatry; Clinical psychology; Mood","score_opus":0.030290058538738594,"score_gpt":0.33621132316131,"score_spread":0.3059212646225714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2926187639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964235,0.00044636094,0.00005276078,0.0003867189,0.00041608384,0.00047296038,0.0000035132718,0.000009887918,0.0017882491],"genre_scores_gemma":[0.99926287,0.00014678526,0.00005978494,0.00007306358,0.0002842915,0.00000415285,3.8846875e-7,0.000020011144,0.00014865542],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9973481,0.0005025152,0.0005153668,0.0003151065,0.0009024094,0.00041646502],"domain_scores_gemma":[0.99903035,0.0002745602,0.000223078,0.00019472516,0.00011665432,0.00016063715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011987715,0.00013506023,0.00026107972,0.0010724433,0.00009183608,0.00008776417,0.00041144676,0.000109084234,0.00004852863],"category_scores_gemma":[0.00033236443,0.00010907288,0.000088462504,0.00093756954,0.0000982821,0.00031389168,0.00009081467,0.001073917,0.000045708828],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00089236646,0.00037999055,0.957345,0.00017524854,0.00001887249,0.000036309695,0.00083072326,0.00001847891,0.016871596,0.00019674435,0.0024447062,0.020789979],"study_design_scores_gemma":[0.0031484715,0.0006890691,0.98920095,0.00017714677,0.0000068045088,0.000037578156,0.0003698537,0.00003207165,0.0034846584,0.0017511671,0.00097553176,0.00012667284],"about_ca_topic_score_codex":0.000011106997,"about_ca_topic_score_gemma":0.000010141995,"teacher_disagreement_score":0.03185599,"about_ca_system_score_codex":0.000068149144,"about_ca_system_score_gemma":0.00015942301,"threshold_uncertainty_score":0.46656945},"labels":[],"label_agreement":null},{"id":"W2926443144","doi":"10.1089/cap.2019.0015","title":"Inflammatory Cytokines in Children and Adolescents with Depressive Disorders: A Systematic Review and Meta-Analysis","year":2019,"lang":"en","type":"review","venue":"Journal of Child and Adolescent Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Meta-analysis; Depression (economics); Clinical psychology; Medicine; Major depressive disorder; Web of science; Cytokine; Systematic review; Psychology; Psychiatry; MEDLINE; Internal medicine; Cognition; Biology","score_opus":0.02638652138945288,"score_gpt":0.321279638830874,"score_spread":0.29489311744142116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2926443144","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003647453,0.9961205,0.000008419271,0.0005947084,0.00007976207,0.0027522205,0.0000418386,0.000010108787,0.000027682248],"genre_scores_gemma":[0.0063785384,0.98851967,0.0000058832925,0.0049296124,0.000054702683,0.00004194153,0.0000027412352,0.000042968608,0.000023914865],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9962226,0.0010014111,0.0014481308,0.0006782203,0.00029551622,0.00035410543],"domain_scores_gemma":[0.9972511,0.00014123021,0.0020776768,0.00025270166,0.00004819376,0.00022910311],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041421334,0.0006614118,0.006136604,0.0008485281,0.00008658635,0.000075359654,0.0003954679,0.0002024163,0.000039547856],"category_scores_gemma":[0.000094273186,0.00038834685,0.00088830834,0.0006652112,0.00025135197,0.00022768619,0.00012045316,0.0009630402,0.0000029603254],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014021472,0.00048503355,0.00082798325,0.9633823,0.029660622,0.00005113002,0.00004691391,0.000003431966,0.000004923462,0.000012047786,0.0005908009,0.0047946176],"study_design_scores_gemma":[0.0044401204,0.00026767058,0.0022295183,0.14814761,0.8284493,0.0023473415,0.000014592836,0.000003324039,0.0000030374265,0.000019508516,0.013130431,0.0009475337],"about_ca_topic_score_codex":6.6176966e-7,"about_ca_topic_score_gemma":0.0000041870485,"teacher_disagreement_score":0.81523466,"about_ca_system_score_codex":0.000026103617,"about_ca_system_score_gemma":0.00007099703,"threshold_uncertainty_score":0.9998568},"labels":[],"label_agreement":null},{"id":"W2927195072","doi":"10.1111/aji.13115","title":"Poly(I:C) alters placental and fetal brain amino acid transport in a rat model of maternal immune activation","year":2019,"lang":"en","type":"article","venue":"American Journal of Reproductive Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Placenta; Amino acid; Fetus; Amino acid transporter; Transporter; Pregnancy; Internal medicine; Endocrinology; Biology; Chemistry; Medicine; Biochemistry; Gene; Genetics","score_opus":0.010104116633340493,"score_gpt":0.23558402732458897,"score_spread":0.22547991069124848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2927195072","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99736655,0.00034842113,0.00043615716,0.0013100345,0.0002515355,0.00016719979,0.000006057571,0.0000083962295,0.00010562124],"genre_scores_gemma":[0.99908817,0.0001220905,0.00045713683,0.0001705769,0.00002765845,0.0000021726853,9.627599e-7,0.000018555613,0.00011265665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984124,0.00020107353,0.00053748663,0.00038687998,0.00019966609,0.00026251556],"domain_scores_gemma":[0.99878514,0.00010366715,0.0007496427,0.00026223954,0.000062021056,0.000037285285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029646687,0.00016692694,0.000496448,0.0003464639,0.000029994279,0.0000076916795,0.00025861812,0.000043286993,0.000023487071],"category_scores_gemma":[0.00021070155,0.0001502001,0.000096180396,0.00033684337,0.0008254026,0.00039679024,0.0000447461,0.0003480132,0.0000032137893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019272836,0.00012263279,0.011302994,0.000009026931,0.00003006531,0.000011460086,0.0015196392,0.00018484176,0.96347463,0.00016285606,0.000003717681,0.02125083],"study_design_scores_gemma":[0.0015546745,0.0011121689,0.09050345,0.000045000666,0.000006511231,0.00037250295,0.001964476,0.00016437563,0.90387005,0.00024021941,0.000028474531,0.00013809928],"about_ca_topic_score_codex":0.000094906456,"about_ca_topic_score_gemma":0.0000030157516,"teacher_disagreement_score":0.079200454,"about_ca_system_score_codex":0.000074245756,"about_ca_system_score_gemma":0.00010516348,"threshold_uncertainty_score":0.6124982},"labels":[],"label_agreement":null},{"id":"W2935778452","doi":"10.1007/s12035-019-01647-0","title":"Development of a Novel Neuro-immune and Opioid-Associated Fingerprint with a Cross-Validated Ability to Identify and Authenticate Unknown Patients with Major Depression: Far Beyond Differentiation, Discrimination, and Classification","year":2019,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Major depressive disorder; Fingerprint (computing); Artificial intelligence; Linear discriminant analysis; Support vector machine; Psychology; Pattern recognition (psychology); Depression (economics); Medicine; Computer science; Psychiatry; Mood","score_opus":0.01425240073956009,"score_gpt":0.26068207077835287,"score_spread":0.2464296700387928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2935778452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99655074,0.00001377502,0.002384873,0.00017018573,0.00005767026,0.00074377254,0.000023784793,0.000034482928,0.00002070293],"genre_scores_gemma":[0.9991319,0.0000033189358,0.0004431091,0.00028105528,0.0000013100939,0.00003433795,0.000050269544,0.000022526167,0.0000321422],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998462,0.00010686132,0.00033430205,0.0007048207,0.0001628207,0.00022919488],"domain_scores_gemma":[0.999181,0.000113319235,0.00022418307,0.0002692653,0.00012765657,0.000084578205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110116416,0.00020615388,0.0002453409,0.00011541293,0.00013550976,0.000071085604,0.00014278833,0.000080775455,0.000007634316],"category_scores_gemma":[0.0002744109,0.00015812567,0.000017294991,0.0002308685,0.00024000094,0.000104051695,0.0002016205,0.00011083049,0.0000021095602],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015727208,0.00025481114,0.13618399,0.00005615518,0.000012292532,9.704108e-7,0.0006131495,0.0000073150723,0.8616913,0.00041604688,0.0000012432862,0.00060545414],"study_design_scores_gemma":[0.0019051468,0.00017877563,0.842001,0.000027660084,0.000017498412,0.0000036782083,0.000017469274,0.00014669208,0.15543813,0.00005246932,0.000050697654,0.00016076333],"about_ca_topic_score_codex":0.0000060277303,"about_ca_topic_score_gemma":0.000016850065,"teacher_disagreement_score":0.7062532,"about_ca_system_score_codex":0.00001709781,"about_ca_system_score_gemma":0.00003422973,"threshold_uncertainty_score":0.64481777},"labels":[],"label_agreement":null},{"id":"W2936636386","doi":"10.3389/fimmu.2019.00803","title":"The Antidepressant Mirtazapine Inhibits Hepatic Innate Immune Networks to Attenuate Immune-Mediated Liver Injury in Mice","year":2019,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"","keywords":"Immunology; Innate immune system; Immune system; Chemokine; Mirtazapine; Liver injury; Autoimmune hepatitis; CXCL1; Medicine; Inflammation; CXCL2; Cytokine; Chemokine receptor; Biology; Pharmacology; Hepatitis; Internal medicine; Antidepressant","score_opus":0.007168067527125769,"score_gpt":0.21909097299648286,"score_spread":0.2119229054693571,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2936636386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98491585,0.008320973,0.00021826017,0.0012051455,0.0037177857,0.0010306404,0.000011240281,0.000084425374,0.00049569114],"genre_scores_gemma":[0.99319047,0.0046269954,0.00022022278,0.0011029366,0.000026750711,0.00009471414,0.000011960123,0.00005159404,0.0006743879],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9965825,0.00063704996,0.0008137844,0.0007142115,0.00021233497,0.0010401267],"domain_scores_gemma":[0.9983433,0.0004071008,0.00022784104,0.00092152506,0.000040235747,0.000060010472],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005376606,0.00034592138,0.00059518305,0.00050895533,0.00015499776,0.00006457743,0.0014084342,0.0002729591,0.00004370141],"category_scores_gemma":[0.0010242842,0.00028972764,0.00010589699,0.0014282786,0.00039365262,0.00023411056,0.0006737463,0.00084607076,0.0003533198],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022953358,0.00039987126,0.055692416,0.00004710841,0.000079588615,0.000119746415,0.0019165953,0.0013566032,0.90104383,0.0005906145,0.0054660365,0.030992256],"study_design_scores_gemma":[0.009968458,0.0010743149,0.6507999,0.00053351716,0.000019086816,0.000049408824,0.001611437,0.029771945,0.26903492,0.0016286256,0.03355204,0.0019563683],"about_ca_topic_score_codex":0.0004220482,"about_ca_topic_score_gemma":0.00012792317,"teacher_disagreement_score":0.6320089,"about_ca_system_score_codex":0.00014051897,"about_ca_system_score_gemma":0.00007030927,"threshold_uncertainty_score":0.9999555},"labels":[],"label_agreement":null},{"id":"W2936994835","doi":"10.1093/schbul/sbz022.010","title":"4.3 HIPPOCAMPAL SUBFIELDS AND VISUOSPATIAL ASSOCIATIVE MEMORY ACROSS STAGES OF SCHIZOPHRENIA-SPECTRUM DISORDER","year":2019,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; McGill University","funders":"","keywords":"Hippocampal formation; Psychosis; Psychology; Schizophrenia (object-oriented programming); Dentate gyrus; Neuroscience; Episodic memory; Audiology; Content-addressable memory; Hippocampus; Spatial memory; Working memory; Cognition; Psychiatry; Medicine","score_opus":0.00901489146616721,"score_gpt":0.2447871249310813,"score_spread":0.23577223346491408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2936994835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934792,0.00036513314,0.000065211534,0.0027423687,0.0005585493,0.0005885436,0.00014586948,0.00016338167,0.0018917595],"genre_scores_gemma":[0.99712884,0.00015734817,0.00047450294,0.0005421268,0.00013985683,0.00002640969,0.000008294604,0.00006053035,0.0014620692],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99693066,0.00030648656,0.0005457167,0.0008798007,0.0005991989,0.0007381659],"domain_scores_gemma":[0.99825364,0.00063560065,0.00037465716,0.00051152235,0.000051943312,0.00017262818],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003924758,0.00041232677,0.00057466567,0.00012759298,0.0002529706,0.00011708792,0.0004991642,0.0002617069,0.0018220906],"category_scores_gemma":[0.0006710189,0.00038605646,0.0001818866,0.0003915421,0.00040750482,0.00013729607,0.0003462573,0.00053122547,0.000539982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020971794,0.0030745163,0.15421937,0.0011793107,0.0004417158,0.00017471258,0.019131117,0.00039103103,0.5849696,0.052258436,0.020471526,0.1427169],"study_design_scores_gemma":[0.041100163,0.002934308,0.27488235,0.00044349852,0.00009561423,0.00007748256,0.0057887714,0.0005743156,0.62605333,0.01602792,0.028032063,0.003990179],"about_ca_topic_score_codex":0.00017546058,"about_ca_topic_score_gemma":0.00014116803,"teacher_disagreement_score":0.13872673,"about_ca_system_score_codex":0.000037560392,"about_ca_system_score_gemma":0.00009220523,"threshold_uncertainty_score":0.99985915},"labels":[],"label_agreement":null},{"id":"W2937319965","doi":"10.1016/j.ajpath.2019.03.006","title":"Cognitive Decline, Cerebral-Spleen Tryptophan Metabolism, Oxidative Stress, Cytokine Production, and Regulation of the Txnip Gene in a Triple Transgenic Mouse Model of Alzheimer Disease","year":2019,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Oxidative stress; Genetically modified mouse; Alzheimer's disease; Transgene; Disease; Biology; TXNIP; Spleen; Cognitive decline; Medicine; Immunology; Endocrinology; Gene; Internal medicine; Dementia; Biochemistry","score_opus":0.020971303032480817,"score_gpt":0.26404376474360597,"score_spread":0.24307246171112515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937319965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980827,0.00021468248,0.00059016264,0.0005234529,0.00009535824,0.00032400724,0.00014390993,0.00000424678,0.000021508675],"genre_scores_gemma":[0.99904346,0.00015053776,0.00051735545,0.0001874108,0.00003063096,0.0000047592944,0.0000019464608,0.000015807678,0.000048075828],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834317,0.0004512034,0.00053631,0.00025408407,0.00024522477,0.00017002125],"domain_scores_gemma":[0.99862605,0.00010615504,0.00085014355,0.00019250045,0.00015235029,0.00007278266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023335501,0.00013666062,0.00045172364,0.00020014725,0.000029930585,0.000004959594,0.00020291372,0.000033774242,0.000018183495],"category_scores_gemma":[0.0004762363,0.00009901592,0.00012100258,0.0004564355,0.00071503595,0.00018788158,0.00004693059,0.00017986957,6.5589353e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009044555,0.000252671,0.013534636,0.000014140161,0.000029458335,0.00000340609,0.001423235,0.0024133492,0.97895473,0.00027507925,0.0000070771607,0.0021877408],"study_design_scores_gemma":[0.0014602693,0.00025262695,0.193778,0.000037298323,0.00008885593,0.000025296004,0.0005064455,0.0007227719,0.8021413,0.0008831242,0.0000033194872,0.000100689285],"about_ca_topic_score_codex":0.0000133577305,"about_ca_topic_score_gemma":0.000015299467,"teacher_disagreement_score":0.18024336,"about_ca_system_score_codex":0.00000861403,"about_ca_system_score_gemma":0.00014869077,"threshold_uncertainty_score":0.4037752},"labels":[],"label_agreement":null},{"id":"W2937329006","doi":"10.1523/eneuro.0437-18.2019","title":"Maternal Immune Activation during Pregnancy Alters the Behavior Profile of Female Offspring of Sprague Dawley Rats","year":2019,"lang":"en","type":"article","venue":"eNeuro","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation; Government of Canada; University of Saskatchewan","keywords":"Offspring; Prepulse inhibition; Psychology; Schizophrenia (object-oriented programming); Immune system; Pregnancy; Developmental psychology; Physiology; Medicine; Psychiatry; Immunology; Biology","score_opus":0.019282531164778977,"score_gpt":0.2472627720021714,"score_spread":0.2279802408373924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937329006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981476,0.000023932107,0.00000734587,0.000043280983,0.00024334244,0.0005126741,0.0000070522933,0.000027289429,0.0009874507],"genre_scores_gemma":[0.9992555,0.0000148967365,0.000027175443,0.000026077481,0.000014187661,0.000037496546,7.72633e-7,0.000017947536,0.00060595566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990927,0.000072333096,0.00022903725,0.00021982063,0.00022056275,0.00016557291],"domain_scores_gemma":[0.9993464,0.00008903016,0.00019745488,0.00032874555,0.00001804633,0.000020333788],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004215947,0.00009747546,0.00012934895,0.000056344245,0.00004803321,0.0000151273425,0.00029345122,0.000027271863,0.00012717053],"category_scores_gemma":[0.0000893138,0.000075278826,0.00006325524,0.00015323033,0.00006511994,0.00017038929,0.00009538114,0.000103967745,0.000023602144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031603082,0.000061029175,0.01798679,0.00008133965,0.0000018028338,0.000004004023,0.00020752475,0.000049498067,0.98050785,0.00013393186,0.0000020580737,0.0009325401],"study_design_scores_gemma":[0.00024351016,0.000035545203,0.28123417,0.0000962197,0.0000026142511,0.0000044302856,0.00003941985,0.000028386807,0.71824485,0.0000060104826,0.000014194032,0.00005064676],"about_ca_topic_score_codex":0.00003518608,"about_ca_topic_score_gemma":0.0000012195957,"teacher_disagreement_score":0.26324737,"about_ca_system_score_codex":0.000008906456,"about_ca_system_score_gemma":0.000017814305,"threshold_uncertainty_score":0.30697814},"labels":[],"label_agreement":null},{"id":"W2939158812","doi":"10.1093/schbul/sbz018.442","title":"F30. QUINTUPLE HYPOTHESES TARGETED IN SCHIZOPHRENIA: FIGHT FIRE WITH FIRE","year":2019,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Memantine; Galantamine; Schizophrenia (object-oriented programming); Positive and Negative Syndrome Scale; Psychology; Donepezil; NMDA receptor; Internal medicine; Psychiatry; Medicine; Pharmacology; Dementia; Psychosis; Disease; Receptor","score_opus":0.011150126618314764,"score_gpt":0.21157998044008838,"score_spread":0.2004298538217736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939158812","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883013,0.0005217557,0.0000065617405,0.0035045517,0.0003643506,0.0008223176,0.000055637873,0.0003512194,0.006072351],"genre_scores_gemma":[0.9927033,0.0000958196,0.0010877843,0.0017928588,0.00012994853,0.0000860315,0.000017349643,0.000108034954,0.0039788834],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99648595,0.00025013706,0.0004910698,0.0012195932,0.0006362656,0.0009169703],"domain_scores_gemma":[0.99820936,0.00047050836,0.00019372553,0.000858605,0.000046433328,0.00022135419],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00020164384,0.00054556294,0.0005594577,0.00021419048,0.00020232877,0.00016280064,0.00083814084,0.00022687086,0.007437572],"category_scores_gemma":[0.00050823746,0.00044866337,0.00015580385,0.0009595075,0.00024058104,0.00019253729,0.00019097277,0.000690442,0.0063576736],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.04576876,0.0042619207,0.019608209,0.0009705286,0.00019607482,0.0018741125,0.003256858,0.002847536,0.5790594,0.024521723,0.17631626,0.14131857],"study_design_scores_gemma":[0.051702656,0.0031706516,0.10083226,0.001659945,0.00007025126,0.00038902418,0.0013490438,0.0046894145,0.358632,0.006024218,0.46511263,0.0063679237],"about_ca_topic_score_codex":0.0001399743,"about_ca_topic_score_gemma":0.00013535694,"teacher_disagreement_score":0.28879637,"about_ca_system_score_codex":0.00007234599,"about_ca_system_score_gemma":0.00017199437,"threshold_uncertainty_score":0.9997965},"labels":[],"label_agreement":null},{"id":"W2940223517","doi":"10.1093/schbul/sbz019.293","title":"T13. THE ASSOCIATION BETWEEN CHILDHOOD TRAUMA AND INFLAMMATION IN YOUTH AT CLINICAL HIGH RISK FOR PSYCHOSIS","year":2019,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"","keywords":"Prodrome; Psychosis; Psychology; Clinical psychology; Population; Psychiatry; Anxiety; Child abuse; Depression (economics); Neglect; Medicine; Poison control; Injury prevention","score_opus":0.019093968618323572,"score_gpt":0.26091669205023227,"score_spread":0.2418227234319087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2940223517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993076,0.000032574077,0.000018644532,0.0050843298,0.00032115198,0.00087465206,0.00014474378,0.000055793902,0.00039207673],"genre_scores_gemma":[0.9985606,0.000096726224,0.00026341935,0.0003822391,0.0002806434,0.000036965917,0.00002350664,0.000022680138,0.00033319456],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99815816,0.0003842205,0.00043857686,0.0004763378,0.0002536748,0.0002890478],"domain_scores_gemma":[0.99787074,0.0014688246,0.00031667072,0.00026158695,0.00002200376,0.000060142193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009791417,0.00015577016,0.00024234099,0.000072894756,0.00018450462,0.00007359975,0.00023231783,0.00017755985,0.000115299656],"category_scores_gemma":[0.0013497388,0.00011980964,0.000106510604,0.00018556917,0.00005673818,0.000058093185,0.00006819487,0.00031582513,0.00034871302],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001382172,0.00021647182,0.85031754,0.00003641703,0.000060652437,7.5307577e-7,0.0027270296,0.00003998986,0.0014309252,0.0022128457,0.00511044,0.13646476],"study_design_scores_gemma":[0.005160731,0.00015399985,0.9807634,0.000024412724,0.000029284538,4.6559137e-7,0.00009955444,0.00003576612,0.003734634,0.0018436838,0.007963613,0.00019048665],"about_ca_topic_score_codex":0.000060995662,"about_ca_topic_score_gemma":0.00009998158,"teacher_disagreement_score":0.13627428,"about_ca_system_score_codex":0.00005622768,"about_ca_system_score_gemma":0.000015421976,"threshold_uncertainty_score":0.48856956},"labels":[],"label_agreement":null},{"id":"W2942105281","doi":"10.1371/journal.pone.0215101","title":"Bifidobacterium longum R0175 attenuates post-myocardial infarction depressive-like behaviour in rats","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lallemand (Canada); Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Bifidobacterium longum; Behavioural despair test; Lactobacillus helveticus; Medicine; Internal medicine; Myocardial infarction; Bifidobacterium; Endocrinology; Lactobacillus; Biology; Hippocampus; Food science","score_opus":0.026422052742321504,"score_gpt":0.2284365190477901,"score_spread":0.2020144663054686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2942105281","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99700683,0.00003915242,0.0000014917008,0.00069118745,0.00034458397,0.00050433766,0.000028915214,0.00011440984,0.0012690601],"genre_scores_gemma":[0.99757975,0.000037331632,0.00003969828,0.0013845831,0.000090830305,0.000041147396,0.000014525751,0.00003130611,0.00078080554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983999,0.00012148704,0.00022267958,0.0004949717,0.0003799596,0.00038101483],"domain_scores_gemma":[0.9993311,0.00008867959,0.000089764166,0.00035102136,0.000054465847,0.000084956555],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007841456,0.00017855378,0.00024624946,0.00017788852,0.00006311071,0.00007703563,0.0002590152,0.00010974244,0.00023683188],"category_scores_gemma":[0.0002164687,0.0001787595,0.00007022906,0.00030219313,0.00006968147,0.0003504728,0.00010801538,0.00024947574,0.0009548124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007661839,0.00064177305,0.15678409,0.00002596377,0.000009653036,0.000013011378,0.00019536371,0.000006093963,0.84195817,0.000022928802,0.00007852974,0.00018781994],"study_design_scores_gemma":[0.0008715904,0.00013670212,0.44632336,0.000080633356,0.00001791495,0.0000040683276,0.00007110167,0.00009548514,0.55202794,0.00005883941,0.00007245025,0.00023987645],"about_ca_topic_score_codex":0.00009173562,"about_ca_topic_score_gemma":0.000050619998,"teacher_disagreement_score":0.2899302,"about_ca_system_score_codex":0.00004141887,"about_ca_system_score_gemma":0.000039938626,"threshold_uncertainty_score":0.99982303},"labels":[],"label_agreement":null},{"id":"W2942616011","doi":"10.1177/0269881119845820","title":"Glutathione levels and activities of glutathione metabolism enzymes in patients with schizophrenia: A systematic review and meta-analysis","year":2019,"lang":"en","type":"review","venue":"Journal of Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Japan Society for the Promotion of Science","keywords":"Glutathione; Glutathione reductase; GPX3; Glutathione peroxidase; GPX1; Glutathione disulfide; GPX4; GPX6; Oxidative stress; Chemistry; Biochemistry; Internal medicine; Medicine; Enzyme","score_opus":0.0669301808198794,"score_gpt":0.35546682657286355,"score_spread":0.28853664575298416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2942616011","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016359692,0.996137,0.000014783528,0.00011653991,0.00017288262,0.0017604914,0.0001394539,0.000005896358,0.00001698444],"genre_scores_gemma":[0.0057522804,0.9932329,0.00016473541,0.0006453195,0.000022647824,0.00006300063,0.000001729138,0.000038839626,0.00007854589],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9950122,0.0017257571,0.0019677402,0.00048298054,0.0005196854,0.00029160114],"domain_scores_gemma":[0.99472106,0.0011009674,0.0036162022,0.00029560682,0.00012811722,0.0001380791],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009076494,0.00054534245,0.0101876175,0.0013305688,0.000044688924,0.00003320301,0.00043853867,0.00020501077,0.00018621376],"category_scores_gemma":[0.00027919273,0.00031885318,0.0012192209,0.0012944941,0.00023956678,0.00030745042,0.00008576783,0.000735629,0.0000035210132],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041780176,0.00069702556,0.00000673276,0.9104715,0.08412289,0.00006230557,0.00027994392,0.000005027635,0.000058453585,0.00025491562,0.00019595154,0.0034274375],"study_design_scores_gemma":[0.004247959,0.00043110858,0.00015884516,0.01597427,0.9754176,0.00021967945,0.000037388843,0.000001405431,0.000039935177,0.00006297067,0.0028735234,0.0005352898],"about_ca_topic_score_codex":0.000002105098,"about_ca_topic_score_gemma":0.0000030484268,"teacher_disagreement_score":0.8944973,"about_ca_system_score_codex":0.000034349818,"about_ca_system_score_gemma":0.00017887207,"threshold_uncertainty_score":0.9999263},"labels":[],"label_agreement":null},{"id":"W2943873559","doi":"10.1016/j.jpsychires.2019.05.011","title":"Anxiety disorders in childhood are associated with youth IL-6 levels: A mediation study including metabolic stress and childhood traumatic events","year":2019,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul; Hospital de Clínicas de Porto Alegre; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Mediation; Association (psychology); Anxiety; CTQ tree; Clinical psychology; Depression (economics); Medicine; Internal medicine; Psychology; Psychiatry; Poison control; Injury prevention","score_opus":0.058360467632582305,"score_gpt":0.3382104025318724,"score_spread":0.2798499348992901,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943873559","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997226,0.0005391797,0.00000875601,0.000539912,0.000228086,0.0010953775,0.000031717962,0.000014783112,0.00031621224],"genre_scores_gemma":[0.9990488,0.0007000576,0.000050094968,0.000041960844,0.00009075545,0.000010424976,0.0000014479433,0.000034612513,0.000021846035],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9952074,0.0012284451,0.00066682056,0.00042297476,0.0019086469,0.0005656873],"domain_scores_gemma":[0.99833256,0.0005041807,0.00058637717,0.0002510172,0.00014383357,0.00018202185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024762375,0.00021835035,0.00048057156,0.0012600623,0.00022847416,0.000111790156,0.00054553366,0.000097543154,0.000031395222],"category_scores_gemma":[0.0014576016,0.00016247598,0.00009500459,0.002587723,0.00007096342,0.00043850328,0.000116593794,0.0011202986,0.0000075076773],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011538411,0.003125071,0.97505987,0.000038017835,0.000064973814,0.0000056071217,0.017259954,0.00014241149,0.00012541116,0.000032530963,0.000023151735,0.0040076044],"study_design_scores_gemma":[0.0061864955,0.00090868823,0.9651984,0.00015655546,0.000025204601,0.000009729858,0.026374448,0.000075460375,0.000081343904,0.0008006675,0.000006250763,0.00017674311],"about_ca_topic_score_codex":0.000041354506,"about_ca_topic_score_gemma":0.0005021084,"teacher_disagreement_score":0.009861469,"about_ca_system_score_codex":0.00008603047,"about_ca_system_score_gemma":0.00024815096,"threshold_uncertainty_score":0.6625578},"labels":[],"label_agreement":null},{"id":"W2943883651","doi":"10.1016/j.ygeno.2019.05.001","title":"Copy number variation-based gene set analysis reveals cytokine signalling pathways associated with psychiatric comorbidity in patients with inflammatory bowel disease","year":2019,"lang":"en","type":"article","venue":"Genomics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto; University of Manitoba; George & Fay Yee Centre for Healthcare Innovation","funders":"Mitacs; Health Sciences Centre Foundation","keywords":"Biology; Gene; Copy-number variation; Comorbidity; Disease; Psychiatric comorbidity; Inflammatory bowel disease; Cytokine; Genetics; Signalling; Psychiatry; Internal medicine; Medicine; Genome","score_opus":0.011257380270579749,"score_gpt":0.20917651027852896,"score_spread":0.19791913000794922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943883651","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977394,0.000007892601,0.00095507613,0.000042118227,0.00007651246,0.00058667496,0.00042968956,0.000067272274,0.0000953656],"genre_scores_gemma":[0.9985545,0.000008117023,0.00040403742,0.00066083507,0.000021832751,0.000019518771,0.00026226745,0.000038216953,0.000030658488],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981333,0.0001891312,0.00033985806,0.0005556074,0.00041377248,0.00036832117],"domain_scores_gemma":[0.998827,0.00020484965,0.00033055522,0.00039654542,0.00008301499,0.00015804934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022590176,0.0002399465,0.00029812395,0.0002422471,0.0001124493,0.00006561078,0.0002656233,0.00007964311,0.00013018241],"category_scores_gemma":[0.000111094734,0.0002091913,0.000091142596,0.0011841599,0.00005176873,0.00013708905,0.00003334158,0.00018296891,0.0000689584],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044051633,0.000277748,0.93782157,0.000019472001,0.000057533765,0.000009128576,0.00014561765,0.058443125,0.0026886084,0.00005503623,0.000028076713,0.000013541804],"study_design_scores_gemma":[0.0032230213,0.00008935552,0.9854441,0.000016030992,0.00011937084,1.05041835e-7,0.000013328591,0.009548364,0.0010629687,0.00012346743,0.000022520158,0.00033733458],"about_ca_topic_score_codex":0.000021945953,"about_ca_topic_score_gemma":0.00007739587,"teacher_disagreement_score":0.04889476,"about_ca_system_score_codex":0.00020631966,"about_ca_system_score_gemma":0.00024618828,"threshold_uncertainty_score":0.8530574},"labels":[],"label_agreement":null},{"id":"W2944396145","doi":"10.1016/j.physbeh.2019.05.006","title":"The efficacy of anti-inflammatory treatment interventions on depression in individuals with major depressive disorder and high levels of inflammation: A systematic review of randomized clinical trials","year":2019,"lang":"en","type":"review","venue":"Physiology & Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Randomized controlled trial; Psychological intervention; Medicine; Major depressive disorder; Inflammation; Depression (economics); Clinical trial; Antidepressant; Meditation; Internal medicine; Intervention (counseling); Placebo; Physical therapy; Psychiatry; Alternative medicine; Pathology","score_opus":0.132576272563833,"score_gpt":0.4317617295654484,"score_spread":0.29918545700161536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944396145","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07387597,0.9117233,0.0000055902347,0.000027391541,0.00014781811,0.01399699,0.00020318286,0.0000113697815,0.000008395921],"genre_scores_gemma":[0.036224257,0.9612023,0.00001650829,0.000015675078,0.000021378502,0.0024216184,0.000030609506,0.000031529322,0.00003611796],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.98191094,0.012246042,0.004758559,0.0005666724,0.0003055326,0.0002122757],"domain_scores_gemma":[0.9704915,0.022418799,0.0061317715,0.00082639983,0.000084289386,0.000047235382],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.004015901,0.00045071315,0.008994152,0.00022566112,0.00006362214,0.000011045526,0.0004801002,0.00026580627,0.000033128385],"category_scores_gemma":[0.008752625,0.00021130993,0.0017110452,0.00026940127,0.0007491341,0.00006505964,0.00013597372,0.0002722869,0.0000059044073],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019541439,0.0016134548,0.00028732917,0.8819242,0.0007765381,0.000005511479,0.00013227413,0.000003377979,0.000706733,0.00041068284,0.000011182015,0.11217454],"study_design_scores_gemma":[0.058191698,0.0005804272,0.0056011924,0.92174584,0.0122419335,0.000010708321,0.00003536467,0.0000021450144,0.0009711475,0.000030437646,0.00022857125,0.00036055018],"about_ca_topic_score_codex":0.000008483381,"about_ca_topic_score_gemma":0.0000054865586,"teacher_disagreement_score":0.11181399,"about_ca_system_score_codex":0.000025943325,"about_ca_system_score_gemma":0.00019071014,"threshold_uncertainty_score":0.9995971},"labels":[],"label_agreement":null},{"id":"W2944446355","doi":"10.1001/jamapsychiatry.2019.0779","title":"Efficacy of Adjunctive Infliximab vs Placebo in the Treatment of Adults With Bipolar I/II Depression","year":2019,"lang":"en","type":"article","venue":"JAMA Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":193,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa; University Health Network; University of Toronto","funders":"Daiichi Sankyo Europe; National Institute on Drug Abuse; Pfizer; National Institute of Mental Health; National Institutes of Health; Allergan; Sunovion; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Palo Alto Health Sciences; H. Lundbeck A/S; Stanley Medical Research Institute; Purdue University","keywords":"Infliximab; Medicine; Randomized controlled trial; Bipolar disorder; Internal medicine; Depression (economics); Placebo; Adjunctive treatment; Bipolar II disorder; Montgomery–Åsberg Depression Rating Scale; Major depressive episode; Psychiatry; Placebo-controlled study; Pediatrics; Physical therapy; Mood; Major depressive disorder; Double blind; Tumor necrosis factor alpha","score_opus":0.008208050681070542,"score_gpt":0.23652796301684678,"score_spread":0.22831991233577625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944446355","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954898,0.00054914533,0.000005098936,0.0005299358,0.0002404951,0.0007828487,0.000017338387,0.000017528251,0.0023678122],"genre_scores_gemma":[0.9992209,0.000078147015,0.00019944792,0.0003544675,0.000036659396,0.000024085664,0.0000029604298,0.000013729188,0.00006961958],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988772,0.0001295339,0.00021832592,0.00031096212,0.00028002265,0.00018395155],"domain_scores_gemma":[0.999109,0.00024322748,0.00016893871,0.00043154325,0.000017875724,0.000029364293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006950989,0.00015057021,0.00021199323,0.00010689224,0.000045998084,0.0000096836,0.00026943523,0.00007510706,0.00004542287],"category_scores_gemma":[0.00004470058,0.00008399985,0.00007862551,0.00038406817,0.000091994414,0.00011033347,0.000023810902,0.00010700706,0.000014302953],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.051946938,0.016337333,0.7590619,0.00037865003,0.000078626785,0.000012450303,0.046717554,0.0007195546,0.05367604,0.00494472,0.0017807822,0.06434548],"study_design_scores_gemma":[0.04570125,0.0063026147,0.8472024,0.0004839675,0.000027549613,0.000014606519,0.002870738,0.0002634541,0.08979939,0.0002956102,0.0067165084,0.0003219209],"about_ca_topic_score_codex":0.00007404216,"about_ca_topic_score_gemma":0.00008259703,"teacher_disagreement_score":0.088140525,"about_ca_system_score_codex":0.000017848311,"about_ca_system_score_gemma":0.00007050366,"threshold_uncertainty_score":0.34254143},"labels":[],"label_agreement":null},{"id":"W2944883498","doi":"10.1016/j.biopsych.2019.03.771","title":"S20. Depletion of CD4+CD25+ Regulatory T Cells Inhibits the Anxiolytic Effects of Lactobacillus Rhamnosus (JB-1)","year":2019,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Anxiolytic; Lactobacillus rhamnosus; IL-2 receptor; Pharmacology; Biology; Chemistry; Lactobacillus; Bacteria; Immunology; Receptor; T cell; Immune system; Biochemistry","score_opus":0.013993004689023814,"score_gpt":0.22534041407840735,"score_spread":0.21134740938938354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944883498","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99431765,0.0006187957,0.000023965255,0.00034262403,0.0015898411,0.00058498426,0.000014295242,0.000060878356,0.0024469506],"genre_scores_gemma":[0.99847764,0.000097782635,0.00009457086,0.0010696155,0.0000787494,0.000009207063,0.0000024280582,0.000012186349,0.00015780937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983885,0.00027607233,0.00035732947,0.00043386282,0.00024996873,0.00029423673],"domain_scores_gemma":[0.99864113,0.00054322014,0.0002506144,0.00047248494,0.000027340864,0.00006521049],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019714894,0.00019193892,0.0003008547,0.000057452973,0.000061311286,0.000009714235,0.00041652124,0.00021427347,0.00011887011],"category_scores_gemma":[0.00026921977,0.00011106232,0.00019265832,0.00033543896,0.00037662833,0.00005175104,0.000103890256,0.00020225596,0.00013248494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015243057,0.00029159978,0.020062894,0.00015875755,0.000008306465,9.4299156e-7,0.00005627373,0.000023899256,0.96894,0.00821804,0.0011307062,0.00095610454],"study_design_scores_gemma":[0.0016330428,0.0011689434,0.29042032,0.00013040198,0.000012007165,0.000008493301,0.00012912437,0.0000628086,0.6995719,0.004650816,0.0018939577,0.00031819261],"about_ca_topic_score_codex":0.0000067920796,"about_ca_topic_score_gemma":0.0000032954633,"teacher_disagreement_score":0.27035743,"about_ca_system_score_codex":0.00001528126,"about_ca_system_score_gemma":0.000050783434,"threshold_uncertainty_score":0.45289898},"labels":[],"label_agreement":null},{"id":"W2944960906","doi":"10.1016/j.biopsych.2019.03.073","title":"59. LCM-Seq: Pyramidal Neuron Transcriptomic Profiling in the Prefrontal Cortex of Abused Suicides","year":2019,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Transcriptome; Prefrontal cortex; Neuroscience; Cell type; Profiling (computer programming); Gene expression profiling; Biology; Cell; Psychology; Gene; Gene expression; Genetics; Cognition; Computer science","score_opus":0.034181001015421375,"score_gpt":0.26383913112459906,"score_spread":0.22965813010917768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944960906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951299,0.00022080485,0.00001303068,0.00055181317,0.0008820032,0.0006402092,0.000020241674,0.0000629241,0.0024790755],"genre_scores_gemma":[0.9978056,0.000035884903,0.00014912215,0.0018641059,0.00006189172,0.00001559635,0.0000053962294,0.000011257835,0.000051130875],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984099,0.00023953035,0.0003374035,0.00047645788,0.00019601846,0.0003406356],"domain_scores_gemma":[0.9993842,0.00017170454,0.00010004999,0.0002962796,0.000007979587,0.00003973669],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019813556,0.00017997879,0.00023710412,0.000060826,0.000049975646,0.000021645512,0.00058740575,0.00014757301,0.00012544739],"category_scores_gemma":[0.00009019938,0.00010536582,0.00014283945,0.00026738452,0.0002350468,0.00007600729,0.00003087229,0.0003004476,0.00006828381],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030148478,0.00041004558,0.18079375,0.000035162713,0.000002780481,0.0000029630946,0.0002294871,0.000017717002,0.8103346,0.007397791,0.00009387597,0.0003803546],"study_design_scores_gemma":[0.0013330186,0.00061182765,0.9799709,0.00002333307,0.0000034928055,0.000010295266,0.00075464183,0.00021534447,0.012987385,0.003642176,0.00024047717,0.00020714528],"about_ca_topic_score_codex":0.000017864937,"about_ca_topic_score_gemma":0.000034617602,"teacher_disagreement_score":0.7991771,"about_ca_system_score_codex":0.0000116200345,"about_ca_system_score_gemma":0.00004405181,"threshold_uncertainty_score":0.42966935},"labels":[],"label_agreement":null},{"id":"W2945822310","doi":"10.1016/j.schres.2019.05.011","title":"Differential gene expression analysis in blood of first episode psychosis patients","year":2019,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Medical Research Council; National Institute for Health and Care Research; Academy of Medical Sciences; Guy's and St Thomas' Charity; Government of Alberta; Menzies Centre for Australian Studies, King's College London, University of London; National Alliance for Research on Schizophrenia and Depression; South London and Maudsley NHS Foundation Trust","keywords":"Psychosis; Gene; Genetics; Differential diagnosis; Medicine; Psychology; Psychiatry; Biology; Pathology","score_opus":0.032491732414262946,"score_gpt":0.3128411568116451,"score_spread":0.28034942439738214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945822310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984438,0.00003051858,0.000018525225,0.00010645898,0.00012371076,0.0004255024,0.000038685295,0.000022955594,0.0007898339],"genre_scores_gemma":[0.99933314,0.000083874715,0.00020559016,0.000015643393,0.000030811832,0.000037901573,0.000013443294,0.00001989321,0.00025970285],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99690145,0.00041149347,0.00034785247,0.00066301436,0.0011291775,0.00054700713],"domain_scores_gemma":[0.9986301,0.0004263108,0.00008154573,0.00064749067,0.00009528763,0.000119234435],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027583598,0.00015069435,0.00031789532,0.0011556395,0.000117596865,0.00004875754,0.0006731002,0.00009383419,0.0012437416],"category_scores_gemma":[0.00042675366,0.00012964389,0.00016852902,0.0027785462,0.00016263414,0.00014389258,0.00027945076,0.00040940457,0.0001611111],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075727754,0.0009512705,0.59197295,0.00004549455,0.000027504442,0.0000041913154,0.00013052688,0.000047034617,0.40486416,0.0001659438,0.00022048896,0.00081316684],"study_design_scores_gemma":[0.0032529873,0.00016744985,0.35412464,0.000042314266,0.000014734063,2.3233153e-7,0.000024903118,0.0004312165,0.6413015,0.0004371182,0.00005526699,0.0001476176],"about_ca_topic_score_codex":0.00026912542,"about_ca_topic_score_gemma":0.00058513385,"teacher_disagreement_score":0.2378483,"about_ca_system_score_codex":0.000029280034,"about_ca_system_score_gemma":0.000020586924,"threshold_uncertainty_score":0.99966925},"labels":[],"label_agreement":null},{"id":"W2945901155","doi":"10.1016/j.biopsych.2019.03.154","title":"140. Inflammatory Cytokines and Stem Cell Progeny in Major Depression","year":2019,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"","keywords":"Dentate gyrus; Microglia; Inflammation; Hippocampus; Neuroplasticity; Neuroscience; Depression (economics); Proinflammatory cytokine; Cytokine; Neurogenesis; Interleukin; Medicine; Immunology; Biology","score_opus":0.019067028922255442,"score_gpt":0.23932781092966307,"score_spread":0.22026078200740762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945901155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943129,0.00078619225,0.0000033292076,0.00024921863,0.00040513708,0.00036341915,0.000003962726,0.000084890125,0.0037909697],"genre_scores_gemma":[0.998342,0.00007490125,0.00014243573,0.0011194749,0.000054994576,0.000016819075,0.0000011078304,0.0000088669885,0.00023941432],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99888754,0.00010820948,0.000189655,0.00046670047,0.000097058364,0.0002508287],"domain_scores_gemma":[0.9995953,0.0000825625,0.00006140663,0.00018574453,0.0000052210157,0.00006980965],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000887544,0.00014049411,0.00014752088,0.00005770688,0.000046140285,0.000023095103,0.0001939161,0.00016106523,0.000100561694],"category_scores_gemma":[0.000020470898,0.00009326387,0.00004318448,0.00014559519,0.00008617611,0.000071227936,0.000096716125,0.00015715852,0.00017161231],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010088027,0.00011225843,0.77579254,0.000043448963,7.555753e-7,0.0000037490925,0.000031444833,0.0000017560963,0.2206797,0.0012037469,0.00028359613,0.001746137],"study_design_scores_gemma":[0.0020188824,0.0002521825,0.94329584,0.000053456457,0.000001856686,0.000013326018,0.00018482948,0.000058678354,0.042760544,0.0033319655,0.0076580592,0.00037039103],"about_ca_topic_score_codex":0.0000019808076,"about_ca_topic_score_gemma":0.0000064871606,"teacher_disagreement_score":0.17791915,"about_ca_system_score_codex":0.0000080362015,"about_ca_system_score_gemma":0.000022137305,"threshold_uncertainty_score":0.38031903},"labels":[],"label_agreement":null},{"id":"W2946021441","doi":"10.1186/s12979-019-0148-9","title":"Research on immunity and ageing comes of age","year":2019,"lang":"en","type":"editorial","venue":"Immunity & Ageing","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences North","funders":"National Institutes of Health","keywords":"Ageing; Immunity; Medicine; Immunology; Gerontology; Immune system","score_opus":0.06831802439125927,"score_gpt":0.3639882759227124,"score_spread":0.2956702515314531,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946021441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.62283546,0.0006019677,0.0000067689116,0.00010313364,0.33109084,0.00073218864,0.00010618139,0.00015131065,0.04437219],"genre_scores_gemma":[0.9213979,0.0023587984,0.00003606848,0.000098319804,0.07093078,0.000018879098,0.00007938075,0.0001207775,0.004959067],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9939255,0.0026960194,0.00047628087,0.0005716334,0.0015908937,0.00073968084],"domain_scores_gemma":[0.9848769,0.01317008,0.00028066707,0.0013497724,0.00020567658,0.00011692005],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0024412787,0.00038466984,0.00068158837,0.0007406582,0.0009496197,0.00023535117,0.0014262496,0.0007273554,0.00006746506],"category_scores_gemma":[0.009224846,0.00039675945,0.00016531271,0.00075349625,0.0010170056,0.00023103625,0.0009684779,0.004722788,0.00008012168],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006852178,0.0009497213,0.0000270368,0.0024306104,0.00012102215,0.0018505421,0.013359292,0.000052228508,0.22198008,0.0027613991,0.7345772,0.0212057],"study_design_scores_gemma":[0.0017681478,0.0006224308,0.0021798336,0.0019490262,0.000025943467,0.0000030035244,0.0039059324,0.000021978876,0.021093674,0.0013025638,0.9663056,0.00082186464],"about_ca_topic_score_codex":0.0030900023,"about_ca_topic_score_gemma":0.00016336025,"teacher_disagreement_score":0.2985625,"about_ca_system_score_codex":0.00014345879,"about_ca_system_score_gemma":0.0003406677,"threshold_uncertainty_score":0.9998484},"labels":[],"label_agreement":null},{"id":"W2946146013","doi":"10.1016/j.biopsych.2019.03.193","title":"179. Effects of Chronic Haloperidol Treatment on Brain Volume in a Rat Model in of Infection-Mediated Neurodevelopmental Disorders","year":2019,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Haloperidol; Antipsychotic; Schizophrenia (object-oriented programming); Confounding; Psychosis; Medicine; Neuroscience; Psychology; Internal medicine; Psychiatry; Dopamine","score_opus":0.014578117755185575,"score_gpt":0.24851429127149957,"score_spread":0.233936173516314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946146013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971592,0.00010989086,0.00001643885,0.0005667729,0.00064147735,0.0007446062,0.000009726492,0.000034068697,0.0007178579],"genre_scores_gemma":[0.9989478,0.00022167932,0.00005643691,0.0005865462,0.000014078819,0.00004518,0.000007799693,0.000011847661,0.00010861296],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99859405,0.00018348469,0.00034370768,0.00046754957,0.00012579601,0.0002853912],"domain_scores_gemma":[0.9992843,0.00036484978,0.00010692456,0.00019200065,0.0000052335326,0.000046686968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007316851,0.00020365822,0.00032225493,0.00019046587,0.000020264499,0.000004914859,0.00014946927,0.00014544981,0.00006058033],"category_scores_gemma":[0.00027498594,0.00014931228,0.00010377414,0.00046076888,0.00013068724,0.000055262866,0.000043130494,0.00014883539,0.00005342064],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046600366,0.003626124,0.6629401,0.00015988572,0.000007728015,0.0000036642114,0.00022594539,0.0039578527,0.32291266,0.0011441977,0.00033746843,0.0042183655],"study_design_scores_gemma":[0.0074631954,0.0053945445,0.9479226,0.00018856593,0.0000031132163,0.0000021723956,0.00004489024,0.011428262,0.025007516,0.0015453616,0.00054641376,0.00045339298],"about_ca_topic_score_codex":0.000074170806,"about_ca_topic_score_gemma":0.0003370388,"teacher_disagreement_score":0.29790515,"about_ca_system_score_codex":0.0001042357,"about_ca_system_score_gemma":0.00013253454,"threshold_uncertainty_score":0.60887784},"labels":[],"label_agreement":null},{"id":"W2946199359","doi":"10.1016/j.biopsych.2019.03.671","title":"F134. Association of Neuroinflammation With Duration of Untreated Major Depressive Disorder","year":2019,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Translocator protein; Major depressive disorder; Neuroinflammation; Antidepressant; Persistence (discontinuity); Internal medicine; Medicine; Psychology; Duration (music); Psychiatry; Inflammation; Amygdala; Hippocampus","score_opus":0.011117369838522528,"score_gpt":0.22877426140266705,"score_spread":0.21765689156414453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946199359","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965008,0.000045379642,0.00014104239,0.0005704063,0.0002068074,0.00032779304,0.000017089922,0.00004307819,0.002147639],"genre_scores_gemma":[0.9994646,0.000017478615,0.00019794235,0.00010328574,0.00002458326,0.0000066595676,0.000013894686,0.000006665516,0.00016491568],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990302,0.00013358325,0.00027057374,0.0002499697,0.00017877936,0.00013690881],"domain_scores_gemma":[0.9991985,0.00015857925,0.0004153644,0.00015386689,0.000048644662,0.000025078229],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007351729,0.000102092556,0.00016877828,0.000050385253,0.00003452168,0.0000080521695,0.00012395503,0.000118250755,0.00014653734],"category_scores_gemma":[0.00024964125,0.00006671446,0.000054831242,0.00025854836,0.00005417502,0.00009283808,0.000020835678,0.00008046432,0.000034934452],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019228466,0.00014773334,0.5962596,0.000027018084,0.000007657996,2.400839e-7,0.000032602708,0.000054058666,0.3992163,0.0035897095,0.00010105464,0.00037175886],"study_design_scores_gemma":[0.0020520606,0.00084313867,0.90520567,0.00003216781,0.000011527128,0.0000021108792,0.00008935727,0.00022479842,0.089193106,0.0020250946,0.00016203993,0.00015892206],"about_ca_topic_score_codex":0.0000124035405,"about_ca_topic_score_gemma":0.000021087364,"teacher_disagreement_score":0.3100232,"about_ca_system_score_codex":0.000012968422,"about_ca_system_score_gemma":0.00002857542,"threshold_uncertainty_score":0.2720537},"labels":[],"label_agreement":null},{"id":"W2946366903","doi":"10.3389/fphar.2019.00589","title":"Editorial: Novel Approaches to the Neuropharmacology of Mood Disorders","year":2019,"lang":"en","type":"editorial","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Neuropharmacology; Neuroscience; Mood; Medicine; Mood disorders; Psychiatry; Pharmacology; Psychology","score_opus":0.033970063887702504,"score_gpt":0.2783411166719424,"score_spread":0.24437105278423987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946366903","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006785447,0.00020528545,0.0006667758,0.0021650381,0.9913885,0.0020090474,0.00043781183,0.000080743994,0.0023682513],"genre_scores_gemma":[0.013130149,0.0007956064,0.00032294643,0.00083073543,0.98327,0.00040344184,0.000043591892,0.00015301438,0.001050528],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99502075,0.0008027538,0.0008168686,0.0013925637,0.0009411668,0.0010258869],"domain_scores_gemma":[0.9958346,0.002837761,0.00050524407,0.0005830668,0.00006844164,0.00017092118],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00061993586,0.0006481443,0.0010901922,0.00068554527,0.0001258863,0.000035573834,0.0026284421,0.0011198377,0.0001165138],"category_scores_gemma":[0.0018831128,0.0005454955,0.0002737278,0.0010641592,0.0006007593,0.00013829158,0.0006219919,0.0022992478,0.00009354537],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007601874,0.00050301064,0.00006985185,0.0001369058,0.000063144485,0.0000022276085,0.0003615516,0.0015178921,0.017168967,0.0000534381,0.97849894,0.00086387555],"study_design_scores_gemma":[0.003572581,0.00032713372,0.000035498753,0.000016090811,0.00008603046,9.842482e-7,0.000105747684,0.00042788885,0.007444974,0.0001764289,0.9873099,0.00049674977],"about_ca_topic_score_codex":0.00004999953,"about_ca_topic_score_gemma":0.00006868666,"teacher_disagreement_score":0.012451605,"about_ca_system_score_codex":0.0001932233,"about_ca_system_score_gemma":0.00052807404,"threshold_uncertainty_score":0.99969965},"labels":[],"label_agreement":null},{"id":"W2946393793","doi":"10.1016/j.isci.2019.05.012","title":"Neuroimmune Responses Mediate Depression-Related Behaviors following Acute Colitis","year":2019,"lang":"en","type":"article","venue":"iScience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Colitis; Depression (economics); Medicine; Inflammation; Psychiatry; Internal medicine","score_opus":0.017413352405770004,"score_gpt":0.28257884488409735,"score_spread":0.2651654924783273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946393793","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927622,0.00016695543,0.000012914729,0.00035108675,0.001584969,0.00030771215,0.0000137645775,0.00020344232,0.0045969402],"genre_scores_gemma":[0.9932797,0.0000407108,0.00006755229,0.00080365705,0.000010046857,0.000015569964,0.0000011584926,0.000020172767,0.00576141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977406,0.00016653172,0.00025749643,0.0007006296,0.000595743,0.0005389533],"domain_scores_gemma":[0.9988483,0.00038521286,0.00010052213,0.000508075,0.000016739607,0.00014111884],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002335595,0.00017518713,0.00018561025,0.00015574544,0.0002932252,0.00012055306,0.0008303734,0.00007407013,0.00029294103],"category_scores_gemma":[0.0005965312,0.00015159664,0.00012858935,0.00088237284,0.00025011206,0.00055767066,0.00023692784,0.000212446,0.0008765145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004144922,0.00004688844,0.0067272442,0.0000026460198,0.000001963685,0.00014426502,0.00044061645,0.000020705409,0.9890722,0.00026467183,0.00016848436,0.003068887],"study_design_scores_gemma":[0.0014260303,0.00019347519,0.36864015,0.000078305144,0.000020977886,0.00011831917,0.00023180015,0.00073031796,0.6237854,0.00068907876,0.003522653,0.00056349684],"about_ca_topic_score_codex":0.00002248685,"about_ca_topic_score_gemma":0.000003417036,"teacher_disagreement_score":0.36528677,"about_ca_system_score_codex":0.000024994393,"about_ca_system_score_gemma":0.00009759612,"threshold_uncertainty_score":0.9999014},"labels":[],"label_agreement":null},{"id":"W2946911722","doi":"10.1007/s40263-019-00641-3","title":"Methylene Blue in the Treatment of Neuropsychiatric Disorders","year":2019,"lang":"en","type":"review","venue":"CNS Drugs","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Methylene blue; Antidepressant; Anxiolytic; Bipolar disorder; Neuroprotection; Pharmacology; Medicine; Psychiatry; Mania; Psychology; Neuroscience; Lithium (medication); Anxiety; Chemistry","score_opus":0.05658665457901436,"score_gpt":0.3316590149100579,"score_spread":0.27507236033104354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946911722","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00060011167,0.9907262,0.0000030004496,0.000121046,0.0005775407,0.001396636,0.000046090114,0.00002766644,0.0065017114],"genre_scores_gemma":[0.00064080604,0.9983623,0.000011712938,0.00015909824,0.00006217332,0.00011597398,0.000009428143,0.000048211878,0.00059027155],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977005,0.0006369182,0.0004830264,0.00057020545,0.00028518523,0.0003241712],"domain_scores_gemma":[0.9979338,0.00094443775,0.00028689214,0.00079182565,0.000006277851,0.000036780875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012700974,0.0003960137,0.0010241072,0.0003304311,0.00004851593,0.000028439725,0.00080513925,0.00014134409,0.000044578723],"category_scores_gemma":[0.00008132138,0.00022768525,0.00062759913,0.0012467464,0.00012324772,0.000046115634,0.00003548043,0.0002113601,0.00022437926],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000034269244,0.0004724436,0.000002846486,0.0016888226,0.000009405431,0.0000032490725,0.00094546104,0.0000029069327,0.0000030246936,0.00041692457,0.0001640258,0.99628747],"study_design_scores_gemma":[0.00039027893,0.00021419469,0.000022898725,0.00033345324,0.00012248724,0.000004937366,0.0001351395,0.000003387876,0.000015303618,0.000107607884,0.99843216,0.00021814348],"about_ca_topic_score_codex":0.000031478467,"about_ca_topic_score_gemma":0.000017133707,"teacher_disagreement_score":0.9982681,"about_ca_system_score_codex":0.000051597366,"about_ca_system_score_gemma":0.00015402374,"threshold_uncertainty_score":0.92847353},"labels":[],"label_agreement":null},{"id":"W2949204811","doi":"10.1016/j.jagp.2019.06.001","title":"Molecular and Cellular Evidence for Age by Disease Interactions: Updates and Path Forward","year":2019,"lang":"en","type":"review","venue":"American Journal of Geriatric Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; National Alliance for Research on Schizophrenia and Depression","keywords":"Transcriptome; Disease; Neuroscience; Biology; Ageing; Computational biology; Neurotrophic factors; Gene; Gene expression; Bioinformatics; Genetics; Medicine; Receptor; Pathology","score_opus":0.03358195817822837,"score_gpt":0.3328991889566113,"score_spread":0.2993172307783829,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949204811","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0034144141,0.99273825,0.0013254721,0.00043465325,0.001284452,0.00065054756,0.00011477169,0.000015808164,0.000021638823],"genre_scores_gemma":[0.0028266804,0.99484056,0.0013316261,0.000548462,0.00027610638,0.000027701028,0.000007739964,0.00006829884,0.00007283277],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977006,0.000299596,0.00082206854,0.0005479387,0.00029576104,0.0003340703],"domain_scores_gemma":[0.9967018,0.00084825896,0.0017125314,0.00032801554,0.000047870388,0.000361569],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002558657,0.0004321696,0.0013597108,0.00035511178,0.00010667561,0.00015413946,0.00045980306,0.00006626931,0.000013436203],"category_scores_gemma":[0.0005670713,0.00033970462,0.00057794416,0.00053162104,0.00027424633,0.00031242424,0.00009181565,0.00042264382,0.000006345109],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025577217,0.00019201296,0.00007516476,0.008187056,0.00014877057,0.00006292719,0.000057307698,0.0000012755589,0.00034758387,0.00028694683,0.011177579,0.9792076],"study_design_scores_gemma":[0.00077939464,0.0010282199,0.00001938115,0.0067884633,0.0015005871,0.000299773,0.00018880368,0.000014200017,0.000029797384,0.00097202015,0.9876261,0.00075327593],"about_ca_topic_score_codex":0.000004398742,"about_ca_topic_score_gemma":3.3736075e-7,"teacher_disagreement_score":0.97845435,"about_ca_system_score_codex":0.000042616764,"about_ca_system_score_gemma":0.00044187423,"threshold_uncertainty_score":0.9999055},"labels":[],"label_agreement":null},{"id":"W2949544336","doi":"10.1101/030411","title":"Genome-wide association studies suggest limited immune gene enrichment in schizophrenia compared to five autoimmune diseases","year":2015,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Immune system; Schizophrenia (object-oriented programming); Major histocompatibility complex; Biology; Genome-wide association study; Genetic association; Gene; Immunology; Genetics; Single-nucleotide polymorphism; Medicine; Genotype; Psychiatry","score_opus":0.026547122213817023,"score_gpt":0.25232102460720235,"score_spread":0.22577390239338532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949544336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876646,0.006465833,0.000034667282,0.0013493976,0.0016146945,0.0016873023,0.00058908184,0.0005859852,0.000008429056],"genre_scores_gemma":[0.99623615,0.0009946149,0.00071999803,0.0010873041,0.00022472978,0.0005606202,0.0000025441323,0.0001354292,0.000038632825],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.994835,0.00054903416,0.0010456624,0.0016399234,0.0009360913,0.0009942438],"domain_scores_gemma":[0.9959223,0.00082527986,0.00079584477,0.0014132529,0.0006230875,0.00042019604],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00075478945,0.00083470205,0.0012336347,0.00075011334,0.00024386315,0.0003179189,0.0011309971,0.000412584,0.000024856088],"category_scores_gemma":[0.008470855,0.0009108728,0.00021964271,0.0015225327,0.00013882939,0.00022652392,0.001444947,0.00083899655,0.00024370849],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035023113,0.0007815349,0.024519721,0.00027342362,0.00022670953,0.00014533322,0.00023111136,0.0024286387,0.9695505,0.00008667389,0.0014035782,0.0000025745726],"study_design_scores_gemma":[0.0021027764,0.000081625774,0.8342343,0.00033611644,0.000083616964,8.369101e-9,0.000037085,0.0002107832,0.15945724,0.000012828739,0.0022989842,0.0011446642],"about_ca_topic_score_codex":0.000076811164,"about_ca_topic_score_gemma":0.000014939851,"teacher_disagreement_score":0.8100932,"about_ca_system_score_codex":0.0022776856,"about_ca_system_score_gemma":0.0007773361,"threshold_uncertainty_score":0.9998812},"labels":[],"label_agreement":null},{"id":"W2949693233","doi":"10.1016/b978-0-12-803161-2.00023-0","title":"Translational Medicine Strategies in Drug Development for Mood Disorders","year":2019,"lang":"en","type":"book-chapter","venue":"Handbook of behavioral neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Anhedonia; Major depressive disorder; Context (archaeology); Cognition; Mood; Proinflammatory cytokine; Psychology; Mood disorders; Clinical psychology; Psychiatry; Medicine; Neuroscience; Anxiety; Schizophrenia (object-oriented programming); Internal medicine; Biology","score_opus":0.05818450079111841,"score_gpt":0.30492613567107646,"score_spread":0.24674163487995804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949693233","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1753168,0.0038088446,0.018580154,0.0030657968,0.010142599,0.018791195,0.0012729126,0.00081033556,0.76821136],"genre_scores_gemma":[0.86756426,0.0006126225,0.0010236166,0.00046431215,0.000072201125,0.00009942897,0.000040224826,0.00013491063,0.12998843],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99704015,0.00002854563,0.0007067923,0.0009791378,0.0008033886,0.00044201285],"domain_scores_gemma":[0.9989603,0.00021370257,0.0003363398,0.00033750024,0.00004883098,0.000103291044],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018263166,0.00044563014,0.000542676,0.0004258966,0.00013485475,0.000043452696,0.0007254872,0.00016407308,0.00015197501],"category_scores_gemma":[0.000042955973,0.00040895396,0.0001477068,0.00013585866,0.0009983745,0.00035483067,0.000075719065,0.000311804,0.000015720836],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044136329,0.0007554101,0.00054861413,0.00060928176,0.000004466801,0.00002431103,0.0052243206,0.0006289115,0.74907845,0.20019256,0.0011058499,0.041386444],"study_design_scores_gemma":[0.02060749,0.0045928275,0.01397278,0.007928135,0.00020988483,0.000072745584,0.0011725171,0.0012402149,0.40424386,0.12835065,0.41047293,0.0071359742],"about_ca_topic_score_codex":0.000025180412,"about_ca_topic_score_gemma":0.0006075662,"teacher_disagreement_score":0.69224745,"about_ca_system_score_codex":0.000037731723,"about_ca_system_score_gemma":0.0005942288,"threshold_uncertainty_score":0.9998362},"labels":[],"label_agreement":null},{"id":"W2949802704","doi":"10.22215/etd/2019-13423","title":"Fibroblast Growth Factor 2 (FGF2) is Necessary for the Antidepressant Effects of Fluoxetine in Chronically Stressed Mice","year":2019,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Fluoxetine; Antidepressant; Anxiolytic; Major depressive disorder; Anxiety; Mood; Psychology; Mood disorders; Pharmacology; Fibroblast growth factor; Behavioural despair test; Serotonin; Medicine; Internal medicine; Psychiatry; Receptor","score_opus":0.012113944298344646,"score_gpt":0.26376818713247,"score_spread":0.25165424283412535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949802704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919307,0.0005438735,0.0001717368,0.00038021585,0.00064506126,0.0026488253,0.00022132283,0.00006659471,0.003391675],"genre_scores_gemma":[0.9935121,0.00036839643,0.000062001694,0.0005426792,0.000048976483,0.00010258697,0.00009530832,0.000065901426,0.0052020443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979417,0.00009672986,0.00048073335,0.0006873247,0.00038819783,0.00040534989],"domain_scores_gemma":[0.99640906,0.0026815594,0.0003404884,0.0004357541,0.00007998351,0.000053163243],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000075185984,0.0003736279,0.0004955084,0.00016121825,0.00007698046,0.0000566028,0.0008216785,0.00028609086,0.00021809807],"category_scores_gemma":[0.0010469273,0.00025371654,0.00023944247,0.00031994566,0.00008387267,0.00014209934,0.000057799796,0.000324303,0.000026102976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041428805,0.0002550001,0.00015928954,0.0040823333,0.000026572701,0.000004789284,0.0006959322,0.000019138995,0.9883075,0.0005300319,0.0039556692,0.001549506],"study_design_scores_gemma":[0.0018376025,0.00021962379,0.029354217,0.0007338919,0.000018827071,6.1552714e-7,0.000299969,0.0006126845,0.96627563,0.00013126592,0.00020130635,0.00031437445],"about_ca_topic_score_codex":0.00021600373,"about_ca_topic_score_gemma":0.00029507585,"teacher_disagreement_score":0.029194927,"about_ca_system_score_codex":0.000025146912,"about_ca_system_score_gemma":0.00018066914,"threshold_uncertainty_score":0.99999154},"labels":[],"label_agreement":null},{"id":"W2951023215","doi":"10.1002/chin.200952201","title":"ChemInform Abstract: Plectosphaeroic Acids A (Ia), B (Ib), and C (Ic), Indoleamine 2,3‐Dioxygenase Inhibitors Produced in Culture by a Marine Isolate of the Fungus Plectosphaerella cucumerina.","year":2009,"lang":"en","type":"article","venue":"ChemInform","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Indoleamine 2,3-dioxygenase; Fungus; Stereochemistry; Biochemistry; Tryptophan; Botany; Amino acid","score_opus":0.008814735977415396,"score_gpt":0.22944120789649558,"score_spread":0.2206264719190802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951023215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8688489,0.00046467784,8.1010405e-8,0.00037060003,0.00011757874,0.00078533933,0.000029927256,0.00008516693,0.1292977],"genre_scores_gemma":[0.98912144,0.0004136382,0.0000101670275,0.000868647,0.00006095486,0.000034881414,0.00001665641,0.000028467794,0.009445172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99757445,8.4083683e-7,0.0007106837,0.00055653334,0.00047393987,0.000683571],"domain_scores_gemma":[0.9987514,0.000073953874,0.00035651115,0.0005773764,0.000054581487,0.00018620114],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017943438,0.0004520716,0.00044560712,0.00010753918,0.00013049276,0.000069770154,0.00061415706,0.00024384227,0.0001971236],"category_scores_gemma":[0.0006279317,0.00033733572,0.00014460209,0.0010944196,0.00027400863,0.00042007485,0.00025604633,0.0005560344,0.000013701402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022169972,0.00021867412,0.0003438791,0.00018602175,0.000008509376,0.000010093276,0.0017777231,4.5469048e-7,0.8483029,0.00005679895,0.01009052,0.13878274],"study_design_scores_gemma":[0.0018871777,0.00017184501,0.0116496,0.00010277939,0.000006096082,0.000051929153,0.00015610966,0.000014486686,0.9753013,0.00012305561,0.01014221,0.0003933773],"about_ca_topic_score_codex":0.000064027445,"about_ca_topic_score_gemma":0.000048585585,"teacher_disagreement_score":0.13838936,"about_ca_system_score_codex":0.0000963264,"about_ca_system_score_gemma":0.00010728664,"threshold_uncertainty_score":0.99990785},"labels":[],"label_agreement":null},{"id":"W2951837428","doi":"10.1038/s41598-019-44819-7","title":"Indoleamine 2,3-dioxygenase and ischemic heart disease: a Mendelian Randomization study","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Horizon 2020 Framework Programme; National Cancer Institute; Government of Canada; Cancer Research UK; National Institutes of Health; European Commission; Canadian Institutes of Health Research; Genome Canada","keywords":"Mendelian randomization; Medicine; Internal medicine; Odds ratio; Prostate cancer; Confidence interval; Stroke (engine); Genome-wide association study; Oncology; Hazard ratio; Diabetes mellitus; Breast cancer; Single-nucleotide polymorphism; Cancer; Cardiology; Bioinformatics; Endocrinology; Genotype; Biology; Genetics","score_opus":0.01351798174164027,"score_gpt":0.24999505104307418,"score_spread":0.23647706930143392,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951837428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951828,0.00010736293,0.000022527622,0.00016245033,0.0018406026,0.0011220977,0.000002650979,0.00009479817,0.0014646947],"genre_scores_gemma":[0.99282455,0.0000019631843,0.00002538091,0.00022104109,0.000024988953,0.000030063064,0.000009537637,0.000015389473,0.0068471087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978289,0.0001015226,0.00032508874,0.0009831713,0.0005045136,0.000256818],"domain_scores_gemma":[0.9988908,0.000060291604,0.00013701413,0.00068413944,0.00004111673,0.00018663249],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000699118,0.00014058905,0.00018509492,0.00017075127,0.00021654095,0.0002858026,0.00010281772,0.000027890774,0.00029947405],"category_scores_gemma":[0.00057163433,0.00011908971,0.00004964078,0.0005376631,0.0001487812,0.00027210644,0.00009510194,0.00008137505,0.00009004232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015373398,0.00035128236,0.016690502,0.000030672752,0.000003989877,0.00018781557,0.00044793365,0.000055397006,0.97103167,0.000023334258,0.010514601,0.0005090775],"study_design_scores_gemma":[0.009497808,0.00021962261,0.04229623,0.0000852276,0.000026026453,0.00030863332,0.0012573847,0.0015678097,0.87030923,0.0030431512,0.07046462,0.00092426856],"about_ca_topic_score_codex":0.0000057379425,"about_ca_topic_score_gemma":0.000003740884,"teacher_disagreement_score":0.10072244,"about_ca_system_score_codex":0.000016103826,"about_ca_system_score_gemma":0.00008086645,"threshold_uncertainty_score":0.48563376},"labels":[],"label_agreement":null},{"id":"W2952123642","doi":"10.1016/j.biopsych.2018.02.1171","title":"Positron Emission Tomography Studies of the Glial Cell Marker Translocator Protein in Patients With Psychosis: A Meta-analysis Using Individual Participant Data","year":2018,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":124,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Medical Research Council; Vetenskapsrådet; National Institute of Mental Health; Stockholms Läns Landsting; King's College London; Sunovion; NIHR Bristol Biomedical Research Centre; H. Lundbeck A/S; Research Councils UK; National Institute for Health and Care Research; National Institutes of Health; South London and Maudsley NHS Foundation Trust; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Maudsley Charity; Wellcome Trust; Swedish Orphan Biovitrum; King’s College London; Servier; Public Risk Management Association; AstraZeneca; Bristol-Myers Squibb; U.S. Department of Defense; Eli Lilly and Company; American Heart Association; Brain and Behavior Research Foundation","keywords":"Translocator protein; Positron emission tomography; Psychosis; Meta-analysis; Psychology; Medicine; Neuroscience; Psychiatry; Internal medicine; Neuroinflammation; Inflammation","score_opus":0.3808931326165346,"score_gpt":0.39332474397212475,"score_spread":0.012431611355590122,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952123642","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.055526618,0.9411526,0.0000064253463,0.0000671176,0.00026876575,0.0020307926,0.00090287905,0.000025687585,0.000019156083],"genre_scores_gemma":[0.28687197,0.70609945,0.0044083875,0.00094573875,0.0003343479,0.0007788567,0.0003493085,0.00015166146,0.00006026986],"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99531645,0.0014591872,0.0009868533,0.0012659426,0.00051982113,0.0004517745],"domain_scores_gemma":[0.9976327,0.00016331702,0.0007865771,0.0012863415,0.00003975129,0.00009130192],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057285413,0.0005588828,0.0024420067,0.00028587034,0.00014881603,0.000033152304,0.0017490231,0.00034509713,0.000057463443],"category_scores_gemma":[0.00015283014,0.00023397646,0.0014762166,0.0023258587,0.0005915955,0.00008370872,0.00037688465,0.00039780288,0.0000027553292],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0070510115,0.04871263,0.20091015,0.05946944,0.5770902,0.000022818453,0.0026337767,0.000025555591,0.0010347366,0.0005829984,0.010530498,0.09193617],"study_design_scores_gemma":[0.005240531,0.0037837739,0.030079603,0.007247253,0.8527514,0.0000042987544,0.00053674413,0.000028810158,0.00032725965,0.0007965843,0.0950963,0.004107475],"about_ca_topic_score_codex":0.000009480984,"about_ca_topic_score_gemma":0.000032380445,"teacher_disagreement_score":0.27566117,"about_ca_system_score_codex":0.000012236798,"about_ca_system_score_gemma":0.00012076888,"threshold_uncertainty_score":0.9541283},"labels":[],"label_agreement":null},{"id":"W2952829270","doi":"10.22215/etd/2018-13304","title":"Impacts of Early Life Adversity on Microbiota and Immune Functioning in Individuals with Major Depressive Disorder","year":2018,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Depression (economics); Immune system; Major depressive disorder; Psychology; Clinical psychology; Neglect; Medicine; Depressive symptoms; Gut flora; Immunology; Psychiatry; Anxiety","score_opus":0.0096832333079331,"score_gpt":0.23731066142306778,"score_spread":0.22762742811513467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952829270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936192,0.00019465428,0.0000075233143,0.000035947698,0.00013150198,0.0003975376,0.000038645445,0.000031214084,0.005543758],"genre_scores_gemma":[0.9975972,0.000048242797,0.000084825224,0.00017060286,0.000016997048,0.000008960253,0.00006139371,0.000029329432,0.0019824607],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99866605,0.00006929596,0.00025946068,0.0005050848,0.00023873379,0.0002613717],"domain_scores_gemma":[0.999197,0.0001397,0.00030259005,0.0002332886,0.000046837617,0.00008057216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000076669916,0.00026442477,0.00032588394,0.00031830944,0.00013190921,0.00005288957,0.00020278915,0.00020859353,0.00018022158],"category_scores_gemma":[0.00027893877,0.0002131826,0.00005097416,0.0003502576,0.00012994718,0.00018029932,0.000043976976,0.000260525,0.00001950343],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004381684,0.0012138686,0.34959656,0.0009976625,0.00022293246,0.000028342682,0.01519765,0.000030401628,0.620577,0.0011145856,0.001549927,0.0050893943],"study_design_scores_gemma":[0.002108399,0.0004602531,0.8526502,0.00033239418,0.000025172092,0.0000022273696,0.001493531,0.0000030489448,0.14247625,0.000061692874,0.00009057132,0.00029626605],"about_ca_topic_score_codex":0.00076121284,"about_ca_topic_score_gemma":0.0016901777,"teacher_disagreement_score":0.5030536,"about_ca_system_score_codex":0.00001801509,"about_ca_system_score_gemma":0.00011255513,"threshold_uncertainty_score":0.86933345},"labels":[],"label_agreement":null},{"id":"W2953571606","doi":"10.1016/j.bbi.2019.07.001","title":"Brain eicosapentaenoic acid metabolism as a lead for novel therapeutics in major depression","year":2019,"lang":"en","type":"review","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":78,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Center for Complementary and Integrative Health; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Eicosapentaenoic acid; Depression (economics); Microglia; Blood–brain barrier; Neuroscience; Metabolism; Pharmacology; Medicine; Biology; Central nervous system; Internal medicine; Inflammation; Biochemistry; Fatty acid; Polyunsaturated fatty acid","score_opus":0.12550832999206363,"score_gpt":0.38180536159300965,"score_spread":0.256297031600946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953571606","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011520673,0.9829542,0.00007591465,0.00016099196,0.0005618362,0.003945423,0.00037300127,0.00009358021,0.00031435196],"genre_scores_gemma":[0.0033019788,0.99071485,0.00018799711,0.00233297,0.00007783837,0.0009187843,0.00018363279,0.00017234731,0.0021095988],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996869,0.0005625441,0.0007213114,0.0008755817,0.0003126725,0.00065884273],"domain_scores_gemma":[0.99718136,0.0014211641,0.00036406235,0.00088586815,0.000031488267,0.00011604753],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005297693,0.0007123378,0.0015712074,0.0004129953,0.0002968304,0.00016673202,0.0009193617,0.0005679599,0.00006929546],"category_scores_gemma":[0.0005975273,0.0005888982,0.00053882075,0.000532,0.00022336296,0.00026151486,0.00036643498,0.000980362,0.00006851368],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005215821,0.0006654066,0.000021001144,0.002135581,0.000017599114,0.0000069285684,0.00023164609,4.621154e-8,0.032045394,0.00032261678,0.00021978865,0.96428186],"study_design_scores_gemma":[0.0026686636,0.00013702782,0.0011369665,0.001708676,0.00043776928,0.00010983053,0.00009644843,0.0000053840145,0.003146016,0.00009089505,0.98962,0.00084236165],"about_ca_topic_score_codex":0.00009210875,"about_ca_topic_score_gemma":0.000041197763,"teacher_disagreement_score":0.98940015,"about_ca_system_score_codex":0.000069427115,"about_ca_system_score_gemma":0.00024510678,"threshold_uncertainty_score":0.99965626},"labels":[],"label_agreement":null},{"id":"W2955038019","doi":"10.1017/s1092852919001159","title":"Keeping up with the clinical advances: depression","year":2019,"lang":"en","type":"review","venue":"CNS Spectrums","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Major depressive disorder; Glutamatergic; Medicine; Treatment-resistant depression; Opioidergic; Antidepressant; Neuroscience; Depression (economics); Mood; Psychiatry; Bioinformatics; Psychology; Anxiety; Internal medicine; Opioid; Glutamate receptor; Biology; Receptor; (+)-Naloxone","score_opus":0.12200068652127259,"score_gpt":0.3954169407748436,"score_spread":0.27341625425357097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2955038019","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00001966838,0.98073155,0.00015857343,0.00013129535,0.0011741257,0.000983481,0.000011656869,0.0001225503,0.01666709],"genre_scores_gemma":[0.00011496478,0.9960804,0.00003677532,0.0008852926,0.00037116086,0.000050950912,0.000005894335,0.0000740756,0.0023804954],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997465,0.0003886312,0.00045964448,0.00089755666,0.0003431984,0.00044597551],"domain_scores_gemma":[0.9973849,0.0011343348,0.0004231396,0.0009552732,0.000010164797,0.00009217557],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024352124,0.00039787043,0.0010941082,0.00007602568,0.00020168463,0.0000956163,0.0010187863,0.0002203649,0.00016430803],"category_scores_gemma":[0.000283564,0.00019687701,0.00046185346,0.0004534171,0.000310986,0.00019202149,0.00018403294,0.0008778011,0.001067102],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012437305,0.000034869336,0.0000086465925,0.0017219632,0.000012331193,0.000015347177,0.000020619686,0.0000011195835,0.0000025052432,0.0010602874,0.0013792473,0.99573064],"study_design_scores_gemma":[0.0002524476,0.00008054093,0.000008075679,0.003336923,0.00009211563,0.00005750255,0.000017824723,0.0000058150085,0.00003747118,0.00009778185,0.99569696,0.0003165357],"about_ca_topic_score_codex":0.0000016186614,"about_ca_topic_score_gemma":0.000009715569,"teacher_disagreement_score":0.9954141,"about_ca_system_score_codex":0.000040176797,"about_ca_system_score_gemma":0.00021708713,"threshold_uncertainty_score":0.9997107},"labels":[],"label_agreement":null},{"id":"W2955482511","doi":"10.1016/j.bbi.2019.07.003","title":"Interplay between inflammation and neural plasticity: Both immune activation and suppression impair LTP and BDNF expression","year":2019,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":151,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Ministero della Salute","keywords":"Inflammation; Kynurenine pathway; Kynurenine; Lipopolysaccharide; Long-term potentiation; Neuroplasticity; Microglia; Immune system; Neuroinflammation; Synaptic plasticity; Prostaglandin E2; Endocrinology; Immunology; Internal medicine; Medicine; Chemistry; Pharmacology; Neuroscience; Biology; Tryptophan; Biochemistry","score_opus":0.019043479682420542,"score_gpt":0.2847482691381847,"score_spread":0.26570478945576415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2955482511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998907,0.00006776485,0.000057875975,0.00026424442,0.000078379206,0.00046819274,0.000021307946,0.00006220084,0.000073008974],"genre_scores_gemma":[0.99959236,0.000065320455,0.000045900328,0.00007938223,0.000032533637,0.0000173038,0.000021479158,0.000018175358,0.0001275298],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99879116,0.000240107,0.00024151798,0.00034822445,0.0001589736,0.0002200356],"domain_scores_gemma":[0.99900454,0.0005651651,0.000121540346,0.00018310502,0.000017194276,0.00010846347],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017691188,0.00020555792,0.00022789066,0.00012351557,0.00032555137,0.00015551581,0.00010229397,0.00013148278,0.000041136453],"category_scores_gemma":[0.00028289962,0.00017555656,0.000024181243,0.000100054865,0.00020108999,0.00073483924,0.00030434315,0.0003061874,0.0000021887913],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000087329885,0.00002822426,0.05124997,0.00004395719,0.0000015429165,0.0000010610963,0.0008216972,4.6790922e-7,0.9224723,0.000024024781,0.00003385301,0.025235552],"study_design_scores_gemma":[0.00096629484,0.00017217138,0.6270604,0.00008202075,0.000009876389,0.000014101504,0.00034079823,0.00019331377,0.37081522,0.00006438287,0.00012326837,0.0001581524],"about_ca_topic_score_codex":0.00007883794,"about_ca_topic_score_gemma":0.0000036011995,"teacher_disagreement_score":0.57581043,"about_ca_system_score_codex":0.000013105787,"about_ca_system_score_gemma":0.000011771258,"threshold_uncertainty_score":0.7158989},"labels":[],"label_agreement":null},{"id":"W2955948108","doi":"10.1002/ijc.32555","title":"Circulating markers of cellular immune activation in prediagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)","year":2019,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Cancer Epidemiology and Genetics, National Cancer Institute; National Cancer Institute; National Heart, Lung, and Blood Institute; Faculty of Medicine and Health, University of Sydney; Norges Forskningsråd; National Health and Medical Research Council; Medical Research Council; National Institute on Drug Abuse; York University; Cancer Council Victoria; Norges Teknisk-Naturvitenskapelige Universitet; New York City Department of Health and Mental Hygiene; World Health Organization; Centre International de Recherche sur le Cancer; Women's Health Initiative; Norwegian Institute of Public Health; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Lung cancer; Medicine; Neopterin; Internal medicine; Oncology; Kynurenine; Cancer; Prospective cohort study; Odds ratio; Cohort; Cohort study; Gastroenterology; Immunology; Biology","score_opus":0.008661705142776857,"score_gpt":0.2846055497957305,"score_spread":0.27594384465295363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2955948108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943199,0.0034636892,0.00018144716,0.00073600275,0.0007790148,0.0003143814,0.000060429247,0.0000034833147,0.00014164479],"genre_scores_gemma":[0.99668264,0.0027909665,0.000027016638,0.00029844677,0.00013022739,0.000037812795,0.0000014914643,0.000012401332,0.000019011859],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983627,0.00015655457,0.0005379856,0.000185179,0.0005912999,0.00016623504],"domain_scores_gemma":[0.99804175,0.0010147245,0.0006681566,0.000097327604,0.00014773225,0.000030335352],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042396065,0.00011616046,0.00021348483,0.0002198238,0.00002886558,0.00004316062,0.00035725223,0.000050692757,0.00032886578],"category_scores_gemma":[0.00071410334,0.000092263,0.00006931226,0.00022332575,0.00007633884,0.0003067113,0.000042658932,0.0003188526,2.4372335e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020054146,0.00007390977,0.8526108,0.00003825053,0.00011122411,0.000015851976,0.0007599059,0.0077196597,0.13670851,0.00010978957,0.00008084021,0.0015707155],"study_design_scores_gemma":[0.0025565934,0.00004201902,0.9337171,0.00075469364,0.00007537076,0.0000130776325,0.000276699,0.008988269,0.053077873,0.0002582602,0.000096385935,0.0001436913],"about_ca_topic_score_codex":0.004161251,"about_ca_topic_score_gemma":0.00049498864,"teacher_disagreement_score":0.08363064,"about_ca_system_score_codex":0.0001786776,"about_ca_system_score_gemma":0.00022078285,"threshold_uncertainty_score":0.62905943},"labels":[],"label_agreement":null},{"id":"W2956797945","doi":"10.1101/706887","title":"Ovarian status dictates the neuroinflammatory and behavioral consequences of sub-chronic stress exposure in middle-aged female mice","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chronic stress; Hippocampus; Endocrinology; Internal medicine; Ovariectomized rat; Medicine; Cytokine; Hormone","score_opus":0.027682268157139134,"score_gpt":0.23519778580164755,"score_spread":0.2075155176445084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2956797945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99481076,0.0024568734,0.000012729151,0.00011897036,0.0007723761,0.001186348,0.00047681728,0.00015423339,0.000010874523],"genre_scores_gemma":[0.99852324,0.0009697532,0.00010487891,0.000118778175,0.00008388148,0.0001060307,3.3823366e-7,0.00008831857,0.000004767611],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963654,0.0005523364,0.000686415,0.0011703913,0.0004805822,0.0007448493],"domain_scores_gemma":[0.99759257,0.00040547902,0.0005938719,0.0011109781,0.0001123573,0.00018474822],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042857195,0.0005585324,0.0006076454,0.0003014725,0.00016102561,0.00022089605,0.0008537201,0.0003762815,0.000022303253],"category_scores_gemma":[0.0003502043,0.00049237674,0.00012437414,0.0005241091,0.001100642,0.00021947826,0.0005628289,0.0010270174,0.000013976267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054576383,0.00014024775,0.09290321,0.0006384125,0.000014208214,0.00008029904,0.00012284592,0.00015374685,0.9055373,0.00033810225,0.000014728296,0.0000023101918],"study_design_scores_gemma":[0.00079416175,0.000105591345,0.32306284,0.00050176407,0.000030617335,6.6635266e-8,0.000048160626,0.00008327586,0.67482376,0.0000043831583,0.00010402727,0.00044134303],"about_ca_topic_score_codex":0.0002423086,"about_ca_topic_score_gemma":0.00010147453,"teacher_disagreement_score":0.23071355,"about_ca_system_score_codex":0.00013877345,"about_ca_system_score_gemma":0.00097178196,"threshold_uncertainty_score":0.99975276},"labels":[],"label_agreement":null},{"id":"W2959060579","doi":"10.1016/j.yfrne.2019.100772","title":"Stress-induced disturbances along the gut microbiota-immune-brain axis and implications for mental health: Does sex matter?","year":2019,"lang":"en","type":"review","venue":"Frontiers in Neuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Royal Ottawa Mental Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gut–brain axis; Gut flora; Immune system; Anxiety; Mood disorders; Mood; Hormone; Crosstalk; Immunology; Psychology; Biology; Neuroscience; Clinical psychology; Psychiatry; Endocrinology","score_opus":0.04491263354631319,"score_gpt":0.3248004979902589,"score_spread":0.2798878644439457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2959060579","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00086222484,0.97000766,0.000060110746,0.019854557,0.0035923503,0.0040245173,0.0014098694,0.00007580999,0.00011290866],"genre_scores_gemma":[0.0010140561,0.9936051,0.00015529287,0.0030964878,0.00008087167,0.00062970415,0.0001300711,0.00009273037,0.0011957256],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996102,0.0007015985,0.00085295376,0.0012760261,0.00010475607,0.0009626955],"domain_scores_gemma":[0.9976628,0.00080998725,0.0005460171,0.00088527036,0.000013502015,0.00008244901],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006310701,0.0005809217,0.0015531861,0.00034250508,0.00040604483,0.00010478158,0.0011554486,0.00013106615,0.000015492169],"category_scores_gemma":[0.00018489188,0.00038052307,0.00033929374,0.00035283205,0.00048053145,0.00011661415,0.00035578402,0.0006470404,0.00002109346],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039829003,0.00016175648,0.001726274,0.0063082594,0.00007578027,0.000013007312,0.0003207764,4.96445e-7,0.0006043643,0.00062672346,0.1074576,0.88266516],"study_design_scores_gemma":[0.0006033625,0.00015544008,0.0019772376,0.0005685581,0.000041755775,0.00022007852,0.00016879155,0.0000038607627,0.00010812464,0.0002541107,0.99550885,0.00038981086],"about_ca_topic_score_codex":0.000058569705,"about_ca_topic_score_gemma":0.00007037737,"teacher_disagreement_score":0.8880513,"about_ca_system_score_codex":0.000119838995,"about_ca_system_score_gemma":0.00017022212,"threshold_uncertainty_score":0.9998647},"labels":[],"label_agreement":null},{"id":"W2961101336","doi":"10.3389/fimmu.2019.01696","title":"The Role of Inflammation in Depression and Fatigue","year":2019,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":645,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Women and Children’s Health Research Institute","funders":"","keywords":"Depression (economics); Immune system; Inflammation; Medicine; Multiple sclerosis; Immunology; Quality of life (healthcare); Bioinformatics; Biology","score_opus":0.025078883789099136,"score_gpt":0.28286032762276286,"score_spread":0.25778144383366375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2961101336","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00073836197,0.9971916,0.000032158878,0.000010900275,0.00065635756,0.0004801076,0.0000037036318,0.000008368817,0.00087842403],"genre_scores_gemma":[0.00086381525,0.9989015,0.00006699489,0.000005470025,0.0000093351855,0.00004788825,0.000004281502,0.000013916401,0.000086832944],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99868256,0.00037594337,0.00040214148,0.0002674515,0.00007221758,0.00019969956],"domain_scores_gemma":[0.9991349,0.00031422425,0.00025473515,0.00028121928,0.000005972325,0.000008964006],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015129046,0.000150717,0.00060892553,0.00028170718,0.000035672594,0.000012520453,0.00035239657,0.0002674023,0.000002990816],"category_scores_gemma":[0.00037301605,0.00010371378,0.00006301124,0.00027386818,0.00023037371,0.00006630239,0.00012630144,0.00033567607,0.000005110779],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013472354,0.000008986972,0.00024764967,0.0004123789,0.000005904666,0.0000011167467,0.00009726789,0.0000011670402,0.0002495129,0.00046335452,0.00005283373,0.99844635],"study_design_scores_gemma":[0.0003122824,0.000026332316,0.00028199618,0.0014902975,0.000011128868,0.0000067698497,0.00017599469,0.00006357804,0.0007757095,0.002002305,0.99472094,0.00013264248],"about_ca_topic_score_codex":0.000015620932,"about_ca_topic_score_gemma":0.000014892142,"teacher_disagreement_score":0.9983137,"about_ca_system_score_codex":0.000041853986,"about_ca_system_score_gemma":0.00006862056,"threshold_uncertainty_score":0.4229325},"labels":[],"label_agreement":null},{"id":"W2961357065","doi":"10.1016/b978-0-12-813939-4.00027-9","title":"Pharmacoepigenetics of Major Depression","year":2019,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Antidepressant; Depression (economics); Epigenetics; Pharmacogenetics; Major depressive disorder; Medicine; Psychiatry; Bioinformatics; Psychology; Mood; Genetics; Biology; Genotype; Anxiety","score_opus":0.02354676900614056,"score_gpt":0.2644143686575027,"score_spread":0.24086759965136212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2961357065","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008648968,0.0010245693,0.000004666945,0.000021418478,0.00059546396,0.0005556539,0.00006911025,0.000057292295,0.9968069],"genre_scores_gemma":[0.023751002,0.00028772093,0.0000815252,0.0006718256,0.00011703315,0.000006949026,0.0000047859317,0.000094948315,0.9749842],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983347,0.000036246827,0.00039730684,0.0005437638,0.00043001334,0.00025795065],"domain_scores_gemma":[0.9988321,0.00014153199,0.00033004655,0.0005639656,0.000038221235,0.0000941006],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000076888806,0.00034417186,0.00043254218,0.00014534262,0.000054710534,0.000018741002,0.0004976505,0.0002600405,0.00077380345],"category_scores_gemma":[0.000041833675,0.00030935896,0.00024313189,0.0000140086795,0.00019398838,0.00002702235,0.00019871704,0.00035852165,0.00052015594],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029731702,0.000014226925,0.000007378988,0.00015563601,0.000014896317,0.000014309203,0.00007880554,0.0000016349537,0.091580674,0.0033045218,0.00029828877,0.9044999],"study_design_scores_gemma":[0.00047998075,0.000042510324,0.0000140125685,0.00022682053,0.00003547531,0.000006704186,0.000002114507,0.000007844154,0.21152075,0.0040280446,0.7833274,0.0003083498],"about_ca_topic_score_codex":1.5171814e-7,"about_ca_topic_score_gemma":0.0000017237871,"teacher_disagreement_score":0.90419155,"about_ca_system_score_codex":0.000021475465,"about_ca_system_score_gemma":0.00011466133,"threshold_uncertainty_score":0.99993587},"labels":[],"label_agreement":null},{"id":"W2962010096","doi":"10.3389/fncel.2019.00314","title":"Down-Regulation of Essential Synaptic Components by GI-Tract Microbiome-Derived Lipopolysaccharide (LPS) in LPS-Treated Human Neuronal-Glial (HNG) Cells in Primary Culture: Relevance to Alzheimer’s Disease (AD)","year":2019,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Office of Extramural Research, National Institutes of Health; National Eye Institute; University of Toronto; Louisiana Biomedical Research Network; National Institutes of Health; Louisiana State University; National Institute on Aging; Research to Prevent Blindness","keywords":"Lipopolysaccharide; Microglia; Microbiome; Disease; Neuroscience; Immunology; Medicine; Neuroinflammation; Biology; Pathology; Inflammation; Bioinformatics","score_opus":0.012503480591612222,"score_gpt":0.2298768100947716,"score_spread":0.21737332950315938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2962010096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954675,0.0002987416,0.00052769604,0.0001750131,0.0018629549,0.0013997759,0.00012286693,0.00006616013,0.00007928374],"genre_scores_gemma":[0.9983419,0.000101679965,0.00033275402,0.00078131893,0.000022648534,0.000031818498,0.00004531728,0.000053744847,0.0002888115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99537015,0.0004442911,0.0008729194,0.0016506849,0.0007699291,0.0008920299],"domain_scores_gemma":[0.99851906,0.00009965234,0.0003418968,0.0007216746,0.000034595385,0.00028313036],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029591445,0.00047190726,0.0005973695,0.0007444111,0.00012855725,0.00010638908,0.0012539914,0.0001503101,0.00002999418],"category_scores_gemma":[0.00021351197,0.00050640485,0.00013491807,0.001702513,0.00053649966,0.00068487256,0.00028913346,0.00046360216,0.000036872105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002729548,0.0007799086,0.013555781,0.00005973935,0.000002062314,0.00008880514,0.00025381593,0.0018154993,0.98227423,0.000016650738,0.0006508446,0.00022972471],"study_design_scores_gemma":[0.0016654456,0.00015960526,0.07986528,0.000116762734,0.000013577458,0.0000030805425,0.00003743161,0.005322931,0.9116259,0.00009320437,0.00058729394,0.00050947675],"about_ca_topic_score_codex":0.0001248122,"about_ca_topic_score_gemma":0.000018575367,"teacher_disagreement_score":0.0706483,"about_ca_system_score_codex":0.0001707001,"about_ca_system_score_gemma":0.000108642955,"threshold_uncertainty_score":0.99973875},"labels":[],"label_agreement":null},{"id":"W2963960873","doi":"10.1016/j.schres.2020.05.003","title":"Chronic fatigue and fibromyalgia symptoms are key components of deficit schizophrenia and are strongly associated with activated immune-inflammatory pathways","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Fibromyalgia; Schizophrenia (object-oriented programming); Psychology; Psychosis; Medicine; Internal medicine; Clinical psychology; Psychiatry","score_opus":0.06725973208247406,"score_gpt":0.28292587500921657,"score_spread":0.21566614292674252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963960873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972215,0.0007879189,0.000013148322,0.0005564854,0.000029997265,0.00071995764,0.00012122796,0.00019319422,0.00035656916],"genre_scores_gemma":[0.9994979,0.000088962195,0.000096487,0.000016113612,0.000045704237,0.00003654662,0.000018598483,0.00010410541,0.00009557339],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99611926,0.0006475055,0.0004173115,0.00092008576,0.0010804512,0.00081540964],"domain_scores_gemma":[0.99806994,0.0005786917,0.00033357408,0.00042615546,0.00016616985,0.00042547434],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003597958,0.0003743449,0.0005458661,0.00032020622,0.0004231671,0.00016403718,0.00054267474,0.0002045077,0.00011196649],"category_scores_gemma":[0.0011497437,0.00032658107,0.00006817699,0.0010685691,0.0009925402,0.00028488098,0.0004663771,0.0009118718,0.00003524969],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026170248,0.00012389406,0.008919714,0.0004507579,0.000080375976,0.000099483994,0.0004304556,0.000048783964,0.98356974,0.0018786946,0.000118558884,0.0016625142],"study_design_scores_gemma":[0.0140968915,0.0015222748,0.66255003,0.0016887278,0.000027464763,0.000021758784,0.0009922415,0.0027794691,0.31494614,0.00039702162,0.000114307564,0.0008636642],"about_ca_topic_score_codex":0.00003785854,"about_ca_topic_score_gemma":0.000056947076,"teacher_disagreement_score":0.66862357,"about_ca_system_score_codex":0.00010007673,"about_ca_system_score_gemma":0.00024276113,"threshold_uncertainty_score":0.99991864},"labels":[],"label_agreement":null},{"id":"W2964036664","doi":"10.1007/s12640-019-00126-7","title":"Increased Serum Immunoglobulin Responses to Gut Commensal Gram-Negative Bacteria in Unipolar Major Depression and Bipolar Disorder Type 1, Especially When Melancholia Is Present","year":2019,"lang":"en","type":"article","venue":"Neurotoxicity Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Bipolar disorder; Major depressive disorder; Gut–brain axis; Immunology; Mood disorders; Internal medicine; Immunoglobulin A; Gut flora; Medicine; Psychology; Mood; Antibody; Immunoglobulin G; Psychiatry; Anxiety; Lithium (medication)","score_opus":0.051391820857189706,"score_gpt":0.3441467026318226,"score_spread":0.29275488177463294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964036664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99277973,0.00019841046,0.0000050489202,0.003156574,0.0001818907,0.0028185665,0.00015160219,0.00007671749,0.00063145894],"genre_scores_gemma":[0.9960022,0.00017120448,0.0001618513,0.0018795186,0.00007570063,0.000102155835,0.0000048295333,0.00006434654,0.0015381664],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99359435,0.0027105967,0.00041334218,0.0011305775,0.001126817,0.001024297],"domain_scores_gemma":[0.9967095,0.0018057115,0.000079260215,0.0008711611,0.00017281744,0.00036151375],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011077409,0.00033023488,0.0004001094,0.00067926105,0.0003554997,0.0003255974,0.000912912,0.00019915836,0.0009517692],"category_scores_gemma":[0.003160883,0.00030420694,0.00006501511,0.0013923862,0.0003227759,0.000379296,0.0010984469,0.0010771775,0.0005305472],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033427912,0.0003380061,0.13504384,0.00005462709,0.0000072539583,0.0000522168,0.0012741849,0.000003284264,0.8553653,0.000099399345,0.0019052597,0.0025138496],"study_design_scores_gemma":[0.0024920676,0.0007905803,0.56615734,0.000098967044,0.0000028092077,0.000013506418,0.00018330918,0.00024918557,0.38422477,0.00076655106,0.04465389,0.0003670118],"about_ca_topic_score_codex":0.0015725447,"about_ca_topic_score_gemma":0.00038208527,"teacher_disagreement_score":0.4711405,"about_ca_system_score_codex":0.00010230192,"about_ca_system_score_gemma":0.00021502824,"threshold_uncertainty_score":0.9999615},"labels":[],"label_agreement":null},{"id":"W2964457955","doi":"10.1016/j.biopsych.2019.06.031","title":"Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression","year":2019,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of British Columbia","funders":"Cilag; National Institute of Mental Health; NHLBI Division of Intramural Research; Institute of Molecular and Cell Biology; National Health and Medical Research Council; Stanley Center for Psychiatric Research, Broad Institute; University of North Carolina at Chapel Hill; School of Medicine, Emory University; National Institutes of Health; National Institute on Alcohol Abuse and Alcoholism; Centre for Cognitive Ageing and Cognitive Epidemiology; H. Lundbeck A/S; Innovative Medicines Initiative; Chinese Society of Clinical Oncology; Medical Research Council; Siemens Healthineers; Tartu Ülikool; Leids Universitair Medisch Centrum; Westfälische Wilhelms-Universität Münster; Dokuz Eylül Üniversitesi; Vetenskapsrådet; Medizinische Fakultät der Albert-Ludwigs-Universität Freiburg; GGZ Drenthe; Pfizer; Rivierduinen; GGZ inGeest; Gentofte Hospital; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Háskóli Íslands; Bundesministerium für Bildung und Forschung; Erasmus Medisch Centrum; Vrije Universiteit Amsterdam; Janssen Research and Development; ZonMw; Rijksuniversiteit Groningen; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Universiteit Leiden; University of Toronto; Institute of Genetics; Department of Psychiatry, University of Toronto; Universität Greifswald; GGZ Friesland; National Cancer Institute; University College London; Lundbeckfonden; Albert-Ludwigs-Universität Freiburg; Max-Planck-Gesellschaft; King's College London; Department of Health and Social Care; Rheinische Friedrich-Wilhelms-Universität Bonn; Universitair Medisch Centrum Groningen; Università degli Studi di Trento; Virginia Commonwealth University; Philipps-Universität Marburg; Aarhus Universitet; Universität Basel; QIMR Berghofer Medical Research Institute; Højteknologifonden; Johns Hopkins University; National Institute for Health and Care Research; Aarhus Universitetshospital; University of Southern California; Foundation for the National Institutes of Health; Broad Institute; F. Hoffmann-La Roche; Dalhousie University; GlaxoSmithKline; Universitätsmedizin Göttingen; Queensland Brain Institute; Karolinska Institutet; University of Queensland; Emory University; Cardiff University; Kaiser Permanente; Wellcome Trust; National Science Foundation; Massachusetts General Hospital; AstraZeneca; University of Worcester","keywords":"Human leukocyte antigen; Haplotype; Major histocompatibility complex; Allele; Odds ratio; Depression (economics); Genetics; Immunology; Biology; Medicine; Internal medicine; Gene; Antigen","score_opus":0.152375883146754,"score_gpt":0.33726022846362347,"score_spread":0.18488434531686948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964457955","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.028439235,0.9682271,0.000010734424,0.0001813224,0.00051531126,0.001099099,0.00014333533,0.0003409237,0.0010429252],"genre_scores_gemma":[0.034019057,0.9643618,0.00008641156,0.0007018827,0.00023022371,0.00005191498,0.00009049974,0.00007261423,0.00038563044],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99655306,0.00062806305,0.0005354158,0.001404053,0.00031439165,0.0005650067],"domain_scores_gemma":[0.9981797,0.00054878934,0.0006167445,0.00044100566,0.000023722416,0.00019005478],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017836502,0.00066387857,0.0015903963,0.000121766505,0.00030617855,0.00010373253,0.0006227666,0.0009320075,0.000069237205],"category_scores_gemma":[0.0003669306,0.0003690464,0.00034799197,0.0003146165,0.0005008525,0.00007004565,0.00020660741,0.0007679397,0.00012764311],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012526459,0.0076085357,0.07698692,0.019260343,0.0011757175,0.000388721,0.00014305006,0.0000048978804,0.008044095,0.022438427,0.0377897,0.82490695],"study_design_scores_gemma":[0.0016173148,0.0012447455,0.0454983,0.009732201,0.00027036932,0.000053945205,0.00006195505,0.000007303442,0.00012073159,0.0007103096,0.9386331,0.0020497611],"about_ca_topic_score_codex":0.000003380972,"about_ca_topic_score_gemma":0.000029744686,"teacher_disagreement_score":0.9008434,"about_ca_system_score_codex":0.00004019653,"about_ca_system_score_gemma":0.0001383457,"threshold_uncertainty_score":0.99987614},"labels":[],"label_agreement":null},{"id":"W2964514340","doi":"10.3389/fpsyt.2019.00605","title":"Neurobiology and Therapeutic Potential of Cyclooxygenase-2 (COX-2) Inhibitors for Inflammation in Neuropsychiatric Disorders","year":2019,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Cyclooxygenase; Inflammation; Schizophrenia (object-oriented programming); Medicine; Neuroscience; Psychology; Pharmacology; Psychiatry; Psychotherapist; Immunology; Biology; Enzyme","score_opus":0.01806706483334667,"score_gpt":0.2779073285215601,"score_spread":0.2598402636882134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964514340","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0065583796,0.97022706,0.00038265143,0.00021853409,0.019586552,0.0027750202,0.00008227584,0.0000422934,0.00012721852],"genre_scores_gemma":[0.0028291666,0.9955365,0.00091546687,0.00015791897,0.00023086407,0.00015335369,0.000027392147,0.000106029496,0.00004332328],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967148,0.0004902149,0.0011137703,0.0009773687,0.00017524793,0.0005286104],"domain_scores_gemma":[0.9986354,0.00018410485,0.00065209885,0.00045204107,0.000013027358,0.000063297724],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022934056,0.0005351423,0.0014270194,0.0013410547,0.000056368746,0.000028678483,0.0005185668,0.0004905175,0.0000050818994],"category_scores_gemma":[0.00010883728,0.0004924793,0.0004273784,0.001109213,0.00021312397,0.00010972174,0.00008626352,0.0005472406,0.000005477328],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014854886,0.00027330892,0.0020261982,0.015077054,0.00003592723,0.0000017496235,0.000085511725,0.00009273214,0.000071487884,0.0010352756,0.0033319015,0.9778203],"study_design_scores_gemma":[0.00791103,0.0011534332,0.0036901964,0.005267983,0.00058059004,0.000046041463,0.00038101606,0.0013779828,0.00003686471,0.019272422,0.9578003,0.002482108],"about_ca_topic_score_codex":0.000010322757,"about_ca_topic_score_gemma":0.000043801927,"teacher_disagreement_score":0.9753382,"about_ca_system_score_codex":0.00004509,"about_ca_system_score_gemma":0.00027795846,"threshold_uncertainty_score":0.9997527},"labels":[],"label_agreement":null},{"id":"W2965544329","doi":"10.1016/j.biopsych.2019.07.015","title":"Mesenchymal Stromal Cells Modulate Peripheral Stress-Induced Innate Immune Activation Indirectly Limiting the Emergence of Neuroinflammation-Driven Depressive and Anxiety-like Behaviors","year":2019,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CReATe Fertility Centre; Women's College Hospital; University of Toronto","funders":"","keywords":"Proinflammatory cytokine; Neuroinflammation; Innate immune system; Inflammation; Immunology; Mesenchymal stem cell; Immune system; Medicine; Context (archaeology); Biology; Pathology","score_opus":0.020883940382844968,"score_gpt":0.24963792485233746,"score_spread":0.2287539844694925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2965544329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99783653,0.00006247988,0.000017693048,0.00034391988,0.00075992924,0.00047227668,0.000024427074,0.000062262945,0.0004205072],"genre_scores_gemma":[0.99943817,0.00008769646,0.00018570821,0.00015256768,0.00006753881,0.000016507649,0.000007858776,0.000013933139,0.00003001003],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983587,0.00024444886,0.0003709331,0.0005046591,0.00021770563,0.00030355388],"domain_scores_gemma":[0.9991615,0.00013541333,0.0003228261,0.00028445895,0.000035479112,0.000060360497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010376029,0.0002102115,0.00021646854,0.000053735184,0.00019380306,0.000039884813,0.0003571692,0.00015279608,0.00013606304],"category_scores_gemma":[0.00010290257,0.00013958952,0.000103260565,0.00026532394,0.00016448193,0.0001955476,0.00014855324,0.0002974927,0.0000100065645],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006327314,0.00007848179,0.074400894,0.000014725756,0.000005879387,6.809711e-7,0.00021542225,0.00024576642,0.9230448,0.0005095599,0.000015415455,0.0014050959],"study_design_scores_gemma":[0.0005539612,0.00030320807,0.5833931,0.00003628486,0.000007690305,0.0000052636265,0.00061821466,0.0013015468,0.41323072,0.0003019712,0.000020782167,0.00022722369],"about_ca_topic_score_codex":0.000024342455,"about_ca_topic_score_gemma":0.0000059830154,"teacher_disagreement_score":0.5098141,"about_ca_system_score_codex":0.000008159397,"about_ca_system_score_gemma":0.00003663196,"threshold_uncertainty_score":0.56922954},"labels":[],"label_agreement":null},{"id":"W2966352467","doi":"10.1038/s41380-019-0475-4","title":"Transplantation of microbiota from drug-free patients with schizophrenia causes schizophrenia-like abnormal behaviors and dysregulated kynurenine metabolism in mice","year":2019,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":333,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Schizophrenia (object-oriented programming); Kynurenine; Transplantation; Kynurenine pathway; Medicine; Fecal bacteriotherapy; Psychology; Psychiatry; Neuroscience; Biology; Internal medicine; Tryptophan; Genetics; Antibiotics","score_opus":0.0029329211122319965,"score_gpt":0.1890747503995323,"score_spread":0.1861418292873003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2966352467","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99778587,0.0005093707,0.000034129444,0.00016402434,0.00053093955,0.000555497,0.00030035732,0.000051903833,0.00006789498],"genre_scores_gemma":[0.9966948,0.000034589535,0.002753333,0.00031233416,0.000016740472,0.00001054085,0.00010131658,0.00004946324,0.000026903175],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99816585,0.00014113208,0.0003837591,0.0006427255,0.0003432277,0.00032329725],"domain_scores_gemma":[0.9991768,0.000039354825,0.00018543888,0.00046883375,0.000038599017,0.00009097181],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000057719044,0.00031026764,0.00034417716,0.0002671793,0.00005371637,0.00003829756,0.000386767,0.00010979343,0.00006401602],"category_scores_gemma":[0.000014977662,0.00028377314,0.00007637147,0.0005134437,0.00014689879,0.00022516075,0.000059649716,0.00024172183,0.000013430634],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023377342,0.0005151304,0.105061434,0.00009460178,0.000033237444,0.000019643436,0.00039803746,0.00008592124,0.8905263,0.00045119785,0.000101587815,0.00037515783],"study_design_scores_gemma":[0.012603135,0.00010119903,0.7644514,0.00013472003,0.0000810649,0.000009616293,0.000049541664,0.000021576257,0.2218443,0.0002843295,0.000029421797,0.00038971545],"about_ca_topic_score_codex":0.00027167975,"about_ca_topic_score_gemma":0.000527192,"teacher_disagreement_score":0.66868204,"about_ca_system_score_codex":0.000011617815,"about_ca_system_score_gemma":0.000076028824,"threshold_uncertainty_score":0.99996144},"labels":[],"label_agreement":null},{"id":"W2967018534","doi":"10.1016/j.biopha.2019.109301","title":"Pros and cons of 5-HT3 receptor antagonists in neuropsychiatric diseases","year":2019,"lang":"en","type":"editorial","venue":"Biomedicine & Pharmacotherapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Receptor; Pharmacology; Neuroscience; cons; 5-HT receptor; Neurotransmission; Medicine; Psychology; Serotonin; Internal medicine; Computer science","score_opus":0.011032089493217025,"score_gpt":0.30488605333425434,"score_spread":0.2938539638410373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2967018534","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.073759645,0.008532395,0.000008100475,0.0016846645,0.9117002,0.0019675184,0.0017972394,0.00015459007,0.0003956252],"genre_scores_gemma":[0.11526393,0.07168578,0.00010865217,0.0038143045,0.80452764,0.00018801447,0.00042105728,0.0004075416,0.0035831067],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970502,0.00024059605,0.0005918403,0.00087662024,0.0008007307,0.0004399669],"domain_scores_gemma":[0.99799186,0.001001198,0.00039865676,0.00036076325,0.000057976493,0.00018952208],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015962258,0.00046138305,0.00074195315,0.00067201065,0.000054272117,0.000032765198,0.00049802905,0.00027873117,0.00034543543],"category_scores_gemma":[0.00036417393,0.0003847005,0.000112321984,0.00089863426,0.00057563256,0.00010490706,0.000059990798,0.0005355098,0.000033415465],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041046602,0.00028559114,0.00044703388,0.00034117233,0.000012275906,0.000013209563,0.00011962624,2.1895092e-7,0.3375054,0.000010567955,0.6557277,0.0051267794],"study_design_scores_gemma":[0.007238014,0.0005698562,0.00046841239,0.00019097177,0.000032474425,0.0000029023568,0.000022892313,0.00002512176,0.020030798,0.000033555258,0.9709853,0.0003997213],"about_ca_topic_score_codex":0.000052225838,"about_ca_topic_score_gemma":0.0000027437093,"teacher_disagreement_score":0.3174746,"about_ca_system_score_codex":0.000045686236,"about_ca_system_score_gemma":0.0004117701,"threshold_uncertainty_score":0.99986047},"labels":[],"label_agreement":null},{"id":"W2968065037","doi":"10.1111/ejn.14547","title":"Neurobiology of resilience in depression: immune and vascular insights from human and animal studies","year":2019,"lang":"en","type":"review","venue":"European Journal of Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":150,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canada First Research Excellence Fund; Brain and Behavior Research Foundation","keywords":"Depression (economics); Resilience (materials science); Neuroscience; Immune system; Psychology; Animal models of depression; Human studies; Animal studies; Cognitive science; Biology; Medicine; Immunology; Hippocampus; Internal medicine","score_opus":0.09497141703148498,"score_gpt":0.3377142867279491,"score_spread":0.24274286969646414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2968065037","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23327018,0.7659315,0.000004828238,0.00001332392,0.0004163897,0.00020507003,0.0000075015764,0.000007780002,0.00014344213],"genre_scores_gemma":[0.19232692,0.8074278,0.00003239287,0.00011418838,0.00004545067,8.164523e-7,2.7810736e-7,0.000030052028,0.000022054826],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9952396,0.0020509812,0.0012715016,0.00077742635,0.00037129532,0.00028919947],"domain_scores_gemma":[0.9973311,0.00070114894,0.0013780645,0.0004131374,0.000055138975,0.00012143074],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057324365,0.00037958712,0.0014957094,0.00047536468,0.00013852886,0.00006463364,0.0010832893,0.000059092417,0.0000026022267],"category_scores_gemma":[0.0014827811,0.00026659924,0.00020608638,0.00059963396,0.0012116559,0.00034013853,0.0006988195,0.00069556397,0.0000040064892],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007892549,0.0003171603,0.00025755801,0.0042784535,0.000028804649,0.0014519863,0.0015452693,0.000023021339,0.76963437,0.00030938466,0.00007598415,0.22199906],"study_design_scores_gemma":[0.0061781616,0.008070249,0.25955337,0.04850278,0.00070956984,0.002547125,0.0008284119,0.0000678851,0.009995039,0.00049798173,0.66001713,0.0030322685],"about_ca_topic_score_codex":0.0000022109489,"about_ca_topic_score_gemma":0.0000010534297,"teacher_disagreement_score":0.7596393,"about_ca_system_score_codex":0.000016349995,"about_ca_system_score_gemma":0.00008706732,"threshold_uncertainty_score":0.9999786},"labels":[],"label_agreement":null},{"id":"W2968070193","doi":"10.3389/fphar.2019.01044","title":"Effects of the Novel IDO Inhibitor DWG-1036 on the Behavior of Male and Female 3xTg-AD Mice","year":2019,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Brain Institute","keywords":"Kynurenine; Quinolinic acid; Elevated plus maze; Fear conditioning; Kynurenine pathway; Barnes maze; Anxiety; Indoleamine 2,3-dioxygenase; Memory improvement; Medicine; Pharmacology; Psychology; Internal medicine; Endocrinology; Neuroscience; Chemistry; Hippocampus; Cognition; Biochemistry; Psychiatry; Spatial learning; Tryptophan","score_opus":0.012089534835188341,"score_gpt":0.2560073140888046,"score_spread":0.24391777925361627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2968070193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99431664,0.0002324335,0.000021822898,0.0004836996,0.0031178237,0.0011058198,0.000015873438,0.000009347885,0.00069651403],"genre_scores_gemma":[0.9972459,0.00006547039,0.000112904585,0.0016987674,0.000026847418,0.00008186644,2.4466956e-7,0.000013585806,0.0007544066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894774,0.00020059138,0.00019422697,0.0002744381,0.00015509354,0.00022788763],"domain_scores_gemma":[0.9992232,0.00042294263,0.00013888619,0.00016915557,0.000014212568,0.0000316159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013651287,0.00012510981,0.00021845139,0.00008976516,0.0000489731,0.00000548236,0.00039614353,0.0000815889,0.000088485314],"category_scores_gemma":[0.00011114274,0.00008085999,0.00006316739,0.00026156637,0.00040322077,0.000053339845,0.00013406306,0.0002387778,0.000008255442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001314085,0.0003234135,0.009279114,0.00007139309,0.0000072745324,0.0000034251968,0.00034458915,0.000011605345,0.9818343,0.00015735884,0.006898931,0.0009371867],"study_design_scores_gemma":[0.0018883183,0.00014373676,0.028483365,0.000024446636,0.00002512915,0.000004887108,0.0001838928,0.0001454892,0.96681905,0.000058617075,0.0021341469,0.000088939116],"about_ca_topic_score_codex":0.000008193897,"about_ca_topic_score_gemma":0.0000021853289,"teacher_disagreement_score":0.01920425,"about_ca_system_score_codex":0.000023530312,"about_ca_system_score_gemma":0.000033279775,"threshold_uncertainty_score":0.32973745},"labels":[],"label_agreement":null},{"id":"W2968961624","doi":"","title":"Supplemental niacinamide mitigates anxiety symptoms: Three case reports.","year":2005,"lang":"en","type":"article","venue":"Journal of orthomolecular medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Canadian College of Naturopathic Medicine","funders":"","keywords":"Niacinamide; Anxiety; Medicine; Psychiatry; Nicotinamide; Biology; Biochemistry","score_opus":0.01326325432311888,"score_gpt":0.2677725322388323,"score_spread":0.2545092779157134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2968961624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98969275,0.0012770754,0.0013701787,0.0054390035,0.00045256809,0.00017676309,0.0000062046506,0.00003129664,0.0015541512],"genre_scores_gemma":[0.99520427,0.00018042419,0.0008789988,0.0030404285,0.0005580516,0.0000024404856,0.000003281189,0.000029848796,0.00010227365],"study_design_codex":"bench_or_experimental","study_design_gemma":"case_report","domain_scores_codex":[0.997576,0.0001048397,0.00092369877,0.00029170487,0.0007487214,0.00035506376],"domain_scores_gemma":[0.9985391,0.000101289894,0.0006341089,0.0003190364,0.00010906556,0.00029739388],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061613636,0.00022621598,0.00039150356,0.00022639913,0.00013270126,0.000024431678,0.00017884595,0.00006909472,0.0009035027],"category_scores_gemma":[0.00083914533,0.00016636569,0.00020691087,0.00033419556,0.00031301536,0.00025727783,0.000057214147,0.0003669312,0.000011101234],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014694376,0.0003167801,0.0073824534,0.000045160396,0.00007428118,0.15852737,0.00084436906,0.00010979549,0.78897536,0.000619252,0.011552748,0.031405512],"study_design_scores_gemma":[0.0042352206,0.0012301492,0.0037997062,0.00024157466,0.00014479872,0.5497745,0.000728417,0.00025865412,0.3057185,0.0009256393,0.13250902,0.00043377044],"about_ca_topic_score_codex":0.000017810698,"about_ca_topic_score_gemma":0.0000678725,"teacher_disagreement_score":0.48325682,"about_ca_system_score_codex":0.000072660245,"about_ca_system_score_gemma":0.000098563934,"threshold_uncertainty_score":0.9892721},"labels":[],"label_agreement":null},{"id":"W2969235541","doi":"10.1038/s41380-019-0479-0","title":"The complement system in schizophrenia: where are we now and what’s next?","year":2019,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":141,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"University of Toronto; Centre for Addiction and Mental Health","keywords":"Complement system; Schizophrenia (object-oriented programming); C4A; Complement (music); Human leukocyte antigen; Biology; Complement component 2; Gene; Neuroscience; Genetics; Phenotype; Psychology; Immune system; Classical complement pathway; Antigen; Psychiatry","score_opus":0.044025988910917434,"score_gpt":0.3029483442271122,"score_spread":0.2589223553161948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969235541","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007235283,0.99314135,0.000027777563,0.0018134685,0.0029936447,0.0015190572,0.000020358882,0.000072934716,0.00033906123],"genre_scores_gemma":[0.00013710654,0.9989659,0.000095882635,0.0003506294,0.00009427285,0.00013605533,0.0000071062886,0.00008914388,0.00012386439],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99696374,0.0005555282,0.0006399294,0.0009056233,0.0004104491,0.00052474556],"domain_scores_gemma":[0.998353,0.00017055601,0.00042535528,0.0009284439,0.000015139338,0.000107498556],"candidate_categories":["metaepi_narrow","scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.00022719482,0.0005471953,0.0010349796,0.00017599449,0.00022049353,0.0010674723,0.00082586484,0.00021414204,0.000013986477],"category_scores_gemma":[0.000020794665,0.00038044673,0.00037559532,0.0004966753,0.00012874867,0.00028481468,0.00025398884,0.00063696987,0.00022072613],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028515213,0.00011435538,0.000012106978,0.03648755,0.00006230241,0.00010298464,0.00003423873,0.0000033842318,0.000020719122,0.01865816,0.006383015,0.93809265],"study_design_scores_gemma":[0.00060398155,0.000038550064,0.000007974607,0.022367444,0.00008096347,0.00008838794,0.0008973403,0.000020426,0.0000041564394,0.00017713338,0.97528744,0.00042618983],"about_ca_topic_score_codex":0.000004278269,"about_ca_topic_score_gemma":0.00026600462,"teacher_disagreement_score":0.96890444,"about_ca_system_score_codex":0.00008603793,"about_ca_system_score_gemma":0.00024917696,"threshold_uncertainty_score":0.99996954},"labels":[],"label_agreement":null},{"id":"W2969773421","doi":"10.5114/hivar.2019.86373","title":"Prognosis of fungal infection of central nervous system in HIV-infected patients: a retrospective study of 77 patients in Ukraine","year":2019,"lang":"en","type":"article","venue":"HIV & AIDS Review","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Retrospective cohort study; Human immunodeficiency virus (HIV); Central nervous system; Internal medicine; Immunology","score_opus":0.011524746748409259,"score_gpt":0.2411090167750794,"score_spread":0.22958427002667015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969773421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99546194,0.000698682,0.000002633394,0.000005121664,0.00013310034,0.0032245314,0.000047354948,0.00002410507,0.00040255737],"genre_scores_gemma":[0.998563,0.0012725594,0.000013730624,0.000030377554,0.000005348262,0.00007406013,0.000011353792,0.000017399181,0.0000121961775],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974064,0.0005290828,0.00095397246,0.00039986943,0.0004446731,0.00026600578],"domain_scores_gemma":[0.9988062,0.00007662517,0.00059987785,0.00030860546,0.00016508308,0.000043604654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024665368,0.000192973,0.00081892515,0.00026109375,0.0000148457575,0.000005125241,0.00017770418,0.0000560737,0.000043197473],"category_scores_gemma":[0.0007116589,0.00016621653,0.00012502914,0.0015957406,0.000050124134,0.00017273631,0.00008198363,0.00015988969,0.000014247101],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054094704,0.003070838,0.98788923,0.0040951385,0.000009089799,0.0000013482099,0.00055081263,0.000011640491,0.0006082952,0.00009412597,0.000039323462,0.003576083],"study_design_scores_gemma":[0.0029036135,0.0017801422,0.9893256,0.0043741236,0.000027425844,4.8837995e-7,0.00007912417,0.000034760338,0.0012796568,0.000003125333,0.000057351717,0.00013459013],"about_ca_topic_score_codex":0.0002697178,"about_ca_topic_score_gemma":0.00010496528,"teacher_disagreement_score":0.003441493,"about_ca_system_score_codex":0.000150222,"about_ca_system_score_gemma":0.00003630432,"threshold_uncertainty_score":0.6778113},"labels":[],"label_agreement":null},{"id":"W2970478205","doi":"10.1093/schbul/sbz068","title":"Innate Immune Cells and C-Reactive Protein in Acute First-Episode Psychosis and Schizophrenia: Relationship to Psychopathology and Treatment","year":2019,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Schizophrenia (object-oriented programming); Positive and Negative Syndrome Scale; Psychosis; Internal medicine; Innate immune system; Medicine; Antipsychotic; Immunology; C-reactive protein; Psychopathology; Monocyte; Immune system; Gastroenterology; Psychiatry; Inflammation","score_opus":0.012809800281406034,"score_gpt":0.24303720773957627,"score_spread":0.23022740745817022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970478205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885576,0.00036044436,0.000012689021,0.008546711,0.00018012835,0.0016351712,0.000054790165,0.00007861408,0.00057385844],"genre_scores_gemma":[0.9953626,0.00021334633,0.0026610242,0.0004696761,0.000031509328,0.00027637015,0.000004106733,0.00004513103,0.000936267],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976853,0.00022858629,0.00038202043,0.0010581978,0.00017643355,0.00046944502],"domain_scores_gemma":[0.9989068,0.0003237319,0.00012814895,0.00041668993,0.00002058071,0.00020406634],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020348694,0.00038587893,0.00043483934,0.00037035797,0.0002005921,0.000108682085,0.00017828048,0.00018958825,0.000102620725],"category_scores_gemma":[0.00015371466,0.00035129435,0.00005248075,0.00041456407,0.00020904411,0.00011738122,0.00014645423,0.00033807443,0.00033221397],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019046597,0.0010623279,0.056252986,0.00015280399,0.000102521066,0.00020428406,0.004280935,0.000036645888,0.86335486,0.012234533,0.0014091161,0.041862365],"study_design_scores_gemma":[0.033094443,0.004154619,0.7041416,0.00051648,0.000099993704,0.0003201066,0.00043751698,0.00021561359,0.20769905,0.009094002,0.03794133,0.0022852113],"about_ca_topic_score_codex":0.00023082834,"about_ca_topic_score_gemma":0.00042639012,"teacher_disagreement_score":0.65565586,"about_ca_system_score_codex":0.000053439115,"about_ca_system_score_gemma":0.000016909176,"threshold_uncertainty_score":0.9998939},"labels":[],"label_agreement":null},{"id":"W2970490525","doi":"10.1097/nmd.0000000000000989","title":"Reactive Depression: Lost in Translation!","year":2019,"lang":"en","type":"review","venue":"The Journal of Nervous and Mental Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"START Clinic","funders":"","keywords":"Depression (economics); Stressor; Endogenous depression; Etiology; Psychology; Nosology; Clinical psychology; Psychiatry; Psychosocial; Perspective (graphical); Medicine; Mood","score_opus":0.07718067815489991,"score_gpt":0.33797368829404956,"score_spread":0.26079301013914963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970490525","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0025930877,0.9958584,0.0000021724284,0.00011231439,0.00020119529,0.00037411685,0.00005216349,0.0000027046303,0.0008038679],"genre_scores_gemma":[0.008736589,0.99081075,0.0000035500266,0.00017266216,0.00006295051,0.0000021068781,0.0000025839036,0.000016772732,0.00019202929],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99888635,0.0002744847,0.00034396801,0.00013155102,0.00022966308,0.00013398525],"domain_scores_gemma":[0.999123,0.0002663878,0.00032713427,0.00013383175,0.000008421442,0.00014127194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014686486,0.00017073988,0.00044973573,0.000103722465,0.000056017783,0.000026447988,0.00024564817,0.000045856577,0.000059435413],"category_scores_gemma":[0.00004661423,0.0000908125,0.00020422808,0.00013630415,0.00007630017,0.00013857661,0.000039218525,0.0002863754,0.000021491307],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021179522,0.00015174769,0.0000136846875,0.001397046,0.00001446981,0.000090778645,0.00029198392,0.00000272386,0.00013665382,0.000022351884,0.00042380113,0.997243],"study_design_scores_gemma":[0.0013179455,0.00012796598,0.00045030602,0.009297694,0.00046776223,0.0004240109,0.00021722815,0.000021770658,0.000047444923,0.0002835703,0.98702,0.00032427444],"about_ca_topic_score_codex":0.000002695596,"about_ca_topic_score_gemma":0.0000018795305,"teacher_disagreement_score":0.9969187,"about_ca_system_score_codex":0.000035241064,"about_ca_system_score_gemma":0.00012900768,"threshold_uncertainty_score":0.37032264},"labels":[],"label_agreement":null},{"id":"W2971434260","doi":"10.1017/s003329171900182x","title":"Are remitted affective disorders and familial risk of affective disorders associated with metabolic syndrome, inflammation and oxidative stress? – a monozygotic twin study","year":2019,"lang":"en","type":"article","venue":"Psychological Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Health and Medical Research Council; Lundbeckfonden","keywords":"Oxidative stress; Inflammation; Monozygotic twin; Twin study; Medicine; Clinical psychology; Metabolic syndrome; Psychology; Bioinformatics; Psychiatry; Internal medicine; Genetics; Biology; Obesity","score_opus":0.015525774619393131,"score_gpt":0.2789303103415194,"score_spread":0.26340453572212624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971434260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99607027,0.00023899795,0.0001119652,0.00031410242,0.00013398347,0.002217462,0.000039375547,0.00009223114,0.0007815895],"genre_scores_gemma":[0.9992372,0.00045990417,0.000019242001,0.00012270088,0.000019946414,0.00007917167,0.0000060435764,0.000023550869,0.00003227435],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9970152,0.0009950913,0.0003264395,0.0008697115,0.00045716512,0.00033640637],"domain_scores_gemma":[0.9971949,0.0017500544,0.00057467556,0.0002895399,0.00005556635,0.0001353031],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004209705,0.0003473882,0.0007216234,0.00022373952,0.00012121205,0.000016314903,0.00018413815,0.00014144805,0.000056066296],"category_scores_gemma":[0.0040851273,0.00022326295,0.000042002022,0.00090248574,0.0008242441,0.00018520615,0.00007614127,0.00042267184,0.0000051665224],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010941654,0.0020386016,0.9364797,0.000054886765,0.0002880798,0.00003439486,0.0053013437,0.0000753335,0.021225248,0.00023515476,0.0000398989,0.033133216],"study_design_scores_gemma":[0.0073150713,0.0049673268,0.9783148,0.00014758138,0.00011940642,0.000007590366,0.006664034,0.00020834529,0.0006233887,0.001367145,0.000006396087,0.00025890814],"about_ca_topic_score_codex":0.00014554634,"about_ca_topic_score_gemma":0.00057537894,"teacher_disagreement_score":0.04183513,"about_ca_system_score_codex":0.000022669365,"about_ca_system_score_gemma":0.0000056909103,"threshold_uncertainty_score":0.9104399},"labels":[],"label_agreement":null},{"id":"W2971632028","doi":"10.1016/j.psyneuen.2019.104434","title":"Role of the kynurenine pathway and the endocannabinoid system as modulators of inflammation and personality traits","year":2019,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; Canadian Institutes of Health Research; Cumming School of Medicine, University of Calgary","keywords":"Endocannabinoid system; Kynurenine pathway; Inflammation; Personality; Big Five personality traits; Kynurenine; Psychology; Neuroscience; Biology; Medicine; Internal medicine; Social psychology; Genetics; Receptor","score_opus":0.00727358807634005,"score_gpt":0.21517032949056342,"score_spread":0.20789674141422337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971632028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938781,0.00028272343,0.0000023941204,0.0017567095,0.00025429216,0.000516433,0.00001376966,0.000027121583,0.0032684358],"genre_scores_gemma":[0.9995516,0.00006137803,0.0000054840334,0.00016973751,0.000021194757,0.000017199394,2.8457282e-7,0.00001095422,0.0001621493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859524,0.00040327446,0.0002791986,0.0003191575,0.00018889912,0.00021421188],"domain_scores_gemma":[0.9992072,0.00021232691,0.00021954642,0.000298093,0.000029106523,0.000033709657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000066090295,0.00013228618,0.00025202052,0.000057472498,0.00007213546,0.000010330459,0.00026170973,0.0000291219,0.000018139506],"category_scores_gemma":[0.00018034902,0.00007849241,0.00006955598,0.00018177861,0.00062658294,0.00006615416,0.00009575251,0.00015507093,0.0000063720818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002665754,0.000030151794,0.004931166,0.000112177426,0.000010794965,0.0000018101272,0.00094818365,0.000014290968,0.8542679,0.13568455,0.000024847095,0.0037075381],"study_design_scores_gemma":[0.0047555086,0.00022971308,0.29154208,0.000039302533,0.000020424246,0.0005597321,0.0011936034,0.0010238728,0.69391596,0.004463576,0.0020835297,0.00017270712],"about_ca_topic_score_codex":0.000060607807,"about_ca_topic_score_gemma":0.000012693543,"teacher_disagreement_score":0.2866109,"about_ca_system_score_codex":0.0000059974545,"about_ca_system_score_gemma":0.000020787576,"threshold_uncertainty_score":0.32008275},"labels":[],"label_agreement":null},{"id":"W2972817572","doi":"10.1037/hea0000790","title":"Marital quality and inflammation: The moderating role of early life adversity.","year":2019,"lang":"en","type":"article","venue":"Health Psychology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Social Sciences and Humanities Research Council of Canada; Canadian Institutes of Health Research","keywords":"Coping (psychology); Psychology; Clinical psychology; Stressor; Psychoneuroimmunology; Association (psychology); Social support; Protective factor; Medicine; Developmental psychology; Immunology; Internal medicine; Social psychology; Immune system","score_opus":0.057208519553155965,"score_gpt":0.36863936924778834,"score_spread":0.31143084969463236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972817572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9764086,0.00010555726,0.000060056205,0.01577718,0.00013184392,0.00022531809,0.000004509773,0.000021716489,0.007265197],"genre_scores_gemma":[0.9853934,0.00003616187,0.000085986416,0.014371541,0.000031708892,0.0000032576102,5.941685e-7,0.0000044723784,0.0000728472],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998994,0.0002903851,0.00022615498,0.00021114743,0.00010355918,0.00017476433],"domain_scores_gemma":[0.99937737,0.0001937422,0.00014543062,0.00020895216,0.0000136417475,0.000060841],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003013575,0.000057556168,0.00012964041,0.00003221502,0.000112806374,0.000009443922,0.000120056095,0.000047767866,0.00006613846],"category_scores_gemma":[0.0001425256,0.000045570578,0.000021528791,0.00009675754,0.000104710976,0.0000768413,0.0000413452,0.0001300353,0.00004139602],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011089981,0.0004097937,0.32777023,0.0007062476,0.000030476574,0.000004223964,0.030251846,0.00013760629,0.32061785,0.19009262,0.00500899,0.12386112],"study_design_scores_gemma":[0.0011681981,0.00033715487,0.9858712,0.000012770582,0.0000010243681,0.000010370918,0.0005311593,0.0003986585,0.0011695706,0.004874694,0.005514087,0.000111122165],"about_ca_topic_score_codex":0.000052356438,"about_ca_topic_score_gemma":0.000018228011,"teacher_disagreement_score":0.65810096,"about_ca_system_score_codex":0.000005883953,"about_ca_system_score_gemma":0.00004764882,"threshold_uncertainty_score":0.18583143},"labels":[],"label_agreement":null},{"id":"W2973230247","doi":"10.1016/b978-2-294-76430-1.00011-1","title":"Inflammation et immunité","year":2019,"lang":"fr","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Collège d'Études Ostéopathiques de Montréal","funders":"","keywords":"Inflammation; Medicine; Immunology","score_opus":0.025410664131349462,"score_gpt":0.2559266392823586,"score_spread":0.23051597515100913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2973230247","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0035791378,0.0011089353,0.000010859748,0.00057904114,0.0022145512,0.0011938628,0.000056468944,0.00013296181,0.99112415],"genre_scores_gemma":[0.020610929,0.00047229492,0.00020580692,0.003604495,0.00030991802,0.000028380688,0.000033171804,0.00015701281,0.97457796],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99718654,0.00024709763,0.00068167876,0.0007875082,0.0005687664,0.00052840455],"domain_scores_gemma":[0.99781,0.0003421036,0.00047467664,0.001096548,0.00010457514,0.00017208257],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00034787913,0.00069816713,0.00060059305,0.00027827692,0.000234956,0.00018024496,0.0007719523,0.0005854917,0.001457147],"category_scores_gemma":[0.0001614526,0.00072150875,0.0004037887,0.000037985363,0.0005516079,0.00021127998,0.000362222,0.0010895153,0.007985683],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020558022,0.000015277661,0.0000064176256,0.00016963428,0.00001921731,0.000019024426,0.00024339613,0.0000046830314,0.01095876,0.3013483,0.000021753433,0.687173],"study_design_scores_gemma":[0.00052408664,0.00013291051,0.00013628465,0.0007723085,0.00004435463,0.000052248575,0.000032948854,0.00004384032,0.0076625743,0.01067072,0.97917247,0.000755267],"about_ca_topic_score_codex":0.0000025273428,"about_ca_topic_score_gemma":0.000043381497,"teacher_disagreement_score":0.9791507,"about_ca_system_score_codex":0.00010641675,"about_ca_system_score_gemma":0.0005312128,"threshold_uncertainty_score":0.9995236},"labels":[],"label_agreement":null},{"id":"W2973339367","doi":"10.1016/j.neubiorev.2019.09.025","title":"Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders","year":2019,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":116,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Health and Medical Research Council","keywords":"Insulin resistance; Metabolic syndrome; Bipolar disorder; Schizophrenia (object-oriented programming); Proinflammatory cytokine; Neuroinflammation; Medicine; Bioinformatics; Biology; Disease; Inflammation; Psychiatry; Diabetes mellitus; Endocrinology; Immunology; Internal medicine; Mood","score_opus":0.2066906966245025,"score_gpt":0.40729168388204146,"score_spread":0.20060098725753894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2973339367","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011350655,0.9882961,0.000014622127,0.000013776829,0.001932046,0.008212359,0.00014648942,0.00016467886,0.00008485973],"genre_scores_gemma":[0.00039560162,0.9972661,0.00021171501,0.0005527232,0.000078635414,0.0012158527,0.000027427475,0.00016322653,0.000088697234],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99319154,0.0006582714,0.001601676,0.0027944336,0.00062517915,0.0011289198],"domain_scores_gemma":[0.9973303,0.000045758126,0.0011473541,0.0011150622,0.000023595663,0.00033795106],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006002751,0.0011581855,0.00249552,0.00080164813,0.00034695503,0.00041020615,0.0015141134,0.00041309395,0.000025039868],"category_scores_gemma":[0.0011392761,0.000842875,0.0008555558,0.0023274184,0.00046923474,0.00060740375,0.00054311624,0.00085711776,0.00010480946],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011154729,0.0001640609,0.00010410824,0.005975899,2.8766406e-8,0.00001749805,0.000021489153,1.1273092e-7,0.0012577189,0.00014668575,0.00037269224,0.9919286],"study_design_scores_gemma":[0.0005160049,0.00044198372,0.00017951264,0.0053798202,0.0000972476,0.00006679629,0.0000059852764,0.000054999477,0.000009296112,0.00007522335,0.99234337,0.0008297458],"about_ca_topic_score_codex":0.0000052438218,"about_ca_topic_score_gemma":0.0000054099937,"teacher_disagreement_score":0.9919707,"about_ca_system_score_codex":0.000069246686,"about_ca_system_score_gemma":0.0002506537,"threshold_uncertainty_score":0.9994022},"labels":[],"label_agreement":null},{"id":"W2974706807","doi":"10.1177/0706743719874162","title":"mGluR5 Facilitates Long-Term Synaptic Depression in a Stress-Induced Depressive Mouse Model","year":2019,"lang":"en","type":"article","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Metabotropic glutamate receptor; Metabotropic glutamate receptor 5; Long-term potentiation; Long-term depression; Metabotropic receptor; Social defeat; Neuroscience; NMDA receptor; Glutamate receptor; Behavioural despair test; Hippocampus; Glutamatergic; Stimulation; Hippocampal formation; Endocrinology; Receptor; Psychology; Internal medicine; Biology; Medicine; Antidepressant; AMPA receptor","score_opus":0.021086655099632718,"score_gpt":0.2516108470585195,"score_spread":0.23052419195888676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2974706807","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99559367,0.0005216967,0.00003488399,0.0022793848,0.0007229494,0.00022640795,0.00003606873,0.000008890829,0.0005760274],"genre_scores_gemma":[0.9987813,0.000017681386,0.00013524301,0.000698604,0.00006182985,0.0000031164084,7.407102e-7,0.000022183976,0.0002792707],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99851465,0.00018848118,0.0003698882,0.00023044404,0.00026226105,0.00043427298],"domain_scores_gemma":[0.99887675,0.00013392001,0.00024368631,0.00035275717,0.000043877226,0.00034902405],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000215443,0.00017283983,0.00021790001,0.00029849674,0.00020155248,0.000094224546,0.0007572238,0.000101815305,0.00012665811],"category_scores_gemma":[0.00020564681,0.00012196922,0.00012057102,0.00022425153,0.000102788625,0.00025681694,0.000025815436,0.00063553656,0.000056818568],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018073585,0.00016111022,0.89621603,0.00009939998,0.000047875586,0.00011595695,0.0030083219,0.018853929,0.076780416,0.0026001795,0.0006102064,0.0013258203],"study_design_scores_gemma":[0.012619088,0.0012368996,0.72123116,0.0022471256,0.00013951695,0.0009436882,0.004521746,0.020791976,0.1672257,0.06670014,0.0000779943,0.002264932],"about_ca_topic_score_codex":0.001541163,"about_ca_topic_score_gemma":0.16729629,"teacher_disagreement_score":0.17498486,"about_ca_system_score_codex":0.00009971055,"about_ca_system_score_gemma":0.0016563615,"threshold_uncertainty_score":0.84789836},"labels":[],"label_agreement":null},{"id":"W2974907564","doi":"10.1016/j.ibror.2019.07.1659","title":"Age-dependent synaptic transmission alterations underlying depressive like behavior following an early life inflammatory challenge","year":2019,"lang":"en","type":"article","venue":"IBRO Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Neuroscience; Transmission (telecommunications); Psychology; Medicine; Computer science; Telecommunications","score_opus":0.03942683269198772,"score_gpt":0.28859512977344187,"score_spread":0.24916829708145416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2974907564","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99527293,0.0001888759,0.0003338096,0.00008631853,0.00079332804,0.0007537518,0.0000016621656,0.00027651785,0.0022928047],"genre_scores_gemma":[0.99872327,0.000020464078,0.00011560179,0.00025005048,0.000041923595,0.00009194298,0.000006376121,0.00005247623,0.00069788477],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99770564,0.00013334183,0.00048415942,0.00075562403,0.00053393707,0.000387324],"domain_scores_gemma":[0.9987495,0.000097849785,0.00021498255,0.0006260734,0.000023433437,0.00028817228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015324651,0.00023072408,0.00023799713,0.00013175533,0.00027594727,0.00018743347,0.0001984377,0.00014053845,0.00014681541],"category_scores_gemma":[0.00011061788,0.0002224053,0.00016981823,0.00013077843,0.000046635458,0.0007202311,0.000054761436,0.00024864436,0.00006425955],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023301582,0.00033189324,0.010399589,0.000053445892,0.000024827734,0.0067570624,0.00244829,0.00026451718,0.9743501,0.00025289037,0.000029084984,0.0050650225],"study_design_scores_gemma":[0.008490049,0.0029346265,0.5084124,0.0015318171,0.00060844136,0.002602058,0.0037279243,0.0031369957,0.44655064,0.008075167,0.0076549486,0.006274888],"about_ca_topic_score_codex":0.00003498324,"about_ca_topic_score_gemma":0.000022034601,"teacher_disagreement_score":0.5277994,"about_ca_system_score_codex":0.00004032968,"about_ca_system_score_gemma":0.00012762017,"threshold_uncertainty_score":0.9069425},"labels":[],"label_agreement":null},{"id":"W2976148914","doi":"10.1177/0269881119875979","title":"Sex influences in the preventive effects of N-acetylcysteine in a two-hit animal model of schizophrenia","year":2019,"lang":"en","type":"article","venue":"Journal of Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Neurochemical; Acetylcysteine; Striatum; Prefrontal cortex; Parvalbumin; Endocrinology; Internal medicine; Hippocampus; Prepulse inhibition; Schizophrenia (object-oriented programming); Oxidative stress; Hippocampal formation; Psychology; Dopamine; Neuroscience; Medicine; Chemistry; Psychiatry; Cognition","score_opus":0.014847401805180233,"score_gpt":0.32778679738481903,"score_spread":0.3129393955796388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2976148914","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981896,0.00031187403,0.000021167956,0.0003254512,0.00034537428,0.00037289405,0.0000031502548,0.000002623792,0.00042782002],"genre_scores_gemma":[0.99900377,0.00013298914,0.00016220377,0.0006060406,0.00004223062,0.0000067224073,6.51334e-8,0.000008245655,0.00003774701],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99818504,0.0005268679,0.0006230038,0.00016808166,0.0002858678,0.0002111639],"domain_scores_gemma":[0.998436,0.00076213345,0.0006027542,0.000117956275,0.0000442159,0.000036989888],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053498644,0.00012342593,0.0004072145,0.0003422463,0.000013618404,0.0000061665246,0.00055813993,0.00005439885,0.00005273526],"category_scores_gemma":[0.00019054818,0.00008634961,0.00011782821,0.0004990307,0.00014988078,0.00018196469,0.00003900714,0.0003874119,0.000004803996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019998054,0.0004765942,0.0034917796,0.000103071936,0.000015388423,0.00003141151,0.0017804215,0.004132386,0.9870425,0.00022828132,0.00016118916,0.00053715636],"study_design_scores_gemma":[0.0353737,0.0030756877,0.05177724,0.0003189654,0.000051517018,0.000120219585,0.0007976875,0.008041911,0.8954722,0.004615708,0.00008521532,0.000269949],"about_ca_topic_score_codex":0.000011596629,"about_ca_topic_score_gemma":0.000014691665,"teacher_disagreement_score":0.09157032,"about_ca_system_score_codex":0.000021558402,"about_ca_system_score_gemma":0.0001103843,"threshold_uncertainty_score":0.35212347},"labels":[],"label_agreement":null},{"id":"W2977837563","doi":"10.1016/j.neuint.2019.104564","title":"Txnip mediates glucocorticoid-activated NLRP3 inflammatory signaling in mouse microglia","year":2019,"lang":"en","type":"article","venue":"Neurochemistry International","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"TXNIP; Inflammasome; Thioredoxin-Interacting Protein; Microglia; Neuroinflammation; Caspase 1; Inflammation; Thioredoxin; Biology; Endocrinology; Chemistry; Internal medicine; Immunology; Medicine; Oxidative stress","score_opus":0.011252412019279923,"score_gpt":0.2384606576620001,"score_spread":0.22720824564272016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2977837563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99330306,0.000010786794,0.000004729433,0.00030675853,0.0005825089,0.00016864737,0.000024237972,0.000098605764,0.0055006463],"genre_scores_gemma":[0.9955407,0.000015440832,0.00002810523,0.0009724205,0.00012262474,0.00001609363,0.000021630685,0.000027910324,0.0032551184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847734,0.000035675967,0.000312649,0.00050726056,0.000394308,0.00027275784],"domain_scores_gemma":[0.9992975,0.00022916959,0.00013138332,0.00023047868,0.00004276152,0.00006872944],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000056804824,0.00018443655,0.00014459236,0.0001013437,0.000026331332,0.00007134001,0.00053652783,0.00009657345,0.00095709413],"category_scores_gemma":[0.0004883847,0.00019964327,0.00007309311,0.00015830783,0.000059890197,0.00020810855,0.000113513546,0.00031376892,0.000419062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065746324,0.000085932836,0.009574619,0.000031149884,0.0000047943463,0.00003177825,0.00008643462,0.00031260084,0.9894924,0.00006588985,0.00013521918,0.000113421615],"study_design_scores_gemma":[0.0009259537,0.000014658249,0.0022213885,0.000025835734,0.0000010286046,0.000017148279,0.00007247913,0.0007157835,0.9939143,0.00007832659,0.0018209548,0.00019214812],"about_ca_topic_score_codex":0.0000054736547,"about_ca_topic_score_gemma":0.0000013574253,"teacher_disagreement_score":0.0073532304,"about_ca_system_score_codex":0.00007243311,"about_ca_system_score_gemma":0.00006953375,"threshold_uncertainty_score":0.9999562},"labels":[],"label_agreement":null},{"id":"W2979673635","doi":"10.1155/2019/9894238","title":"Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation","year":2019,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Institute of Aging; Augusta University","keywords":"Kynurenine; Lipid peroxidation; Aryl hydrocarbon receptor; Chemistry; Sarcopenia; Muscle atrophy; Endocrinology; Biochemistry; Internal medicine; Oxidative stress; Biology; Skeletal muscle; Tryptophan; Medicine; Transcription factor","score_opus":0.029138228202383598,"score_gpt":0.2464053590526808,"score_spread":0.2172671308502972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979673635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941219,0.0014870142,0.00041910828,0.0006253865,0.00009936879,0.00046344305,0.000014149846,0.00006300846,0.0027066031],"genre_scores_gemma":[0.9976282,0.0006079485,0.00016424074,0.00077647297,0.00015858185,0.000018677594,0.00004567832,0.000025625659,0.0005745647],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811596,0.00027561275,0.00019559426,0.0006928592,0.00041038002,0.00030957087],"domain_scores_gemma":[0.9990011,0.00028603422,0.00016187482,0.000306182,0.000041549833,0.00020325776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023836203,0.0003124057,0.00046366244,0.00016269674,0.00016978991,0.00006058478,0.00015824348,0.00008228096,0.00027980615],"category_scores_gemma":[0.00023485313,0.00021025316,0.000040447503,0.00036355437,0.0006631237,0.00042385724,0.000094672614,0.00023594055,0.00002166546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012017291,0.000100088706,0.0048069535,0.000080944046,0.000019398918,0.0000414784,0.0011649583,6.3430986e-7,0.9818223,0.0012941482,0.00007812778,0.01047078],"study_design_scores_gemma":[0.004731906,0.001266995,0.1636787,0.00021416994,0.00012833074,0.00004548541,0.002934122,0.00007617899,0.81191444,0.00068715855,0.013648849,0.0006736264],"about_ca_topic_score_codex":0.0001905071,"about_ca_topic_score_gemma":0.000031394484,"teacher_disagreement_score":0.16990785,"about_ca_system_score_codex":0.000012928928,"about_ca_system_score_gemma":0.000027777507,"threshold_uncertainty_score":0.8573875},"labels":[],"label_agreement":null},{"id":"W2979951654","doi":"10.1042/bio04101022","title":"Age-associated inflammation alters the aging trajectory","year":2019,"lang":"en","type":"article","venue":"The Biochemist","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Wonder; Feeling; Ambivalence; Diversity (politics); Psychology; Gerontology; Successful aging; Appeal; Social psychology; Medicine; Sociology; Political science","score_opus":0.01648590423350022,"score_gpt":0.2335648099958261,"score_spread":0.21707890576232589,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979951654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839444,0.00004249066,0.0000036085387,0.0018253672,0.00015527799,0.0001671519,0.0000027001493,0.00007597692,0.013783],"genre_scores_gemma":[0.9961161,0.00001240624,0.0000019797242,0.0009280887,0.00006222572,0.000007532181,0.000003389362,0.000010211566,0.0028580725],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932104,0.00007257899,0.00009573455,0.00016482822,0.00017274382,0.00017308253],"domain_scores_gemma":[0.99942,0.00019418668,0.00006784669,0.0002879002,0.000008996265,0.000021076712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018607572,0.000083937106,0.000060573184,0.000013215349,0.00015816087,0.00005931062,0.00037285578,0.000031344767,0.000087200846],"category_scores_gemma":[0.00021337497,0.000047926118,0.000051891046,0.00016696543,0.0001319516,0.000043952958,0.00004260469,0.00011766648,0.00018952986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000056882027,0.00000893615,0.00006750312,0.0000062514205,0.000003110089,9.3746934e-7,0.0006276694,0.000020665144,0.9972007,0.00016077163,0.0011421532,0.0007555908],"study_design_scores_gemma":[0.00024784496,0.000008406629,0.0021263561,0.000012821639,0.0000034839522,0.0000017132554,0.0002504295,0.00019730802,0.99389416,0.00023107696,0.0029388256,0.00008756719],"about_ca_topic_score_codex":0.000013633795,"about_ca_topic_score_gemma":0.000005701097,"teacher_disagreement_score":0.012171667,"about_ca_system_score_codex":0.000030227819,"about_ca_system_score_gemma":0.000018666906,"threshold_uncertainty_score":0.24360861},"labels":[],"label_agreement":null},{"id":"W2980409795","doi":"10.1016/j.jocn.2019.10.002","title":"Sex difference in IL-6 modulation of cognition among Chinese individuals with major depressive disorder","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"China Scholarship Council; Health and Family Planning Commission of Wuhan Municipality; National Natural Science Foundation of China","keywords":"Major depressive disorder; Medicine; Cognition; Montreal Cognitive Assessment; Internal medicine; Body mass index; Population; Clinical psychology; Psychiatry; Cognitive impairment","score_opus":0.0360422350351382,"score_gpt":0.33798596593832814,"score_spread":0.30194373090318993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980409795","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99801564,0.000011961229,0.0007351667,0.00017508629,0.00043651907,0.0002705497,0.0000109449375,0.000009820763,0.00033431832],"genre_scores_gemma":[0.9990743,0.00006424565,0.00013238023,0.0005623569,0.000044107288,0.000002529036,3.4159243e-7,0.0000124179505,0.00010736157],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99694365,0.00038661802,0.0011447605,0.0004207489,0.0008477974,0.0002564276],"domain_scores_gemma":[0.9969738,0.001342909,0.001194688,0.00024251569,0.000103680824,0.00014236617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00076938956,0.00016502076,0.00051666825,0.00022974859,0.000054913446,0.000052293213,0.00058944785,0.00009088725,0.00003152479],"category_scores_gemma":[0.004577306,0.00010919285,0.00013538926,0.000810225,0.0005538804,0.00067008415,0.00009396696,0.0005182358,0.000004775482],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013275306,0.00040170274,0.8949691,0.000016297101,0.0000016139944,0.000020002672,0.000100270285,0.0011399428,0.100568414,0.000044760858,0.0000055490673,0.0025995788],"study_design_scores_gemma":[0.0024008895,0.0007442025,0.98378336,0.00010549867,0.000007010012,0.000029238578,0.00004032707,0.004025766,0.0076361257,0.0010789193,0.00001830311,0.00013035472],"about_ca_topic_score_codex":0.0000075831144,"about_ca_topic_score_gemma":0.000016207725,"teacher_disagreement_score":0.09293229,"about_ca_system_score_codex":0.0000064710157,"about_ca_system_score_gemma":0.000115249895,"threshold_uncertainty_score":0.54797935},"labels":[],"label_agreement":null},{"id":"W2980624541","doi":"10.1038/s41380-019-0548-4","title":"Antidepressant efficacy of a selective organic cation transporter blocker in a mouse model of depression","year":2019,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Société d'Accélération du Transfert de Technologies; Agence Nationale de la Recherche","keywords":"Antidepressant; Anhedonia; Monoamine neurotransmitter; Fluoxetine; Pharmacology; Psychology; Citalopram; Ventral tegmental area; Chlordiazepoxide; Dopaminergic; Neuroscience; Medicine; Anxiety; Dopamine; Serotonin; Psychiatry; Internal medicine; Receptor","score_opus":0.008054320615502063,"score_gpt":0.23277202156463941,"score_spread":0.22471770094913734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980624541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956864,0.000104179366,0.00302811,0.00007694408,0.00008903106,0.00039879905,0.000013436767,0.000023815146,0.0005792539],"genre_scores_gemma":[0.9989461,0.0000123203345,0.00072652946,0.0002044264,0.000004473359,0.0000070451524,0.0000028950203,0.000026208538,0.00007005616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988405,0.000068532936,0.00030181522,0.00036986033,0.00023882181,0.00018047004],"domain_scores_gemma":[0.99942523,0.000025607173,0.00013874235,0.00034788897,0.000027635384,0.000034872377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006604533,0.0001290322,0.00020894936,0.00015529443,0.000015050497,0.000004667146,0.00020853545,0.00007492199,0.000034192857],"category_scores_gemma":[0.000037036665,0.000121916964,0.00009588311,0.00036144166,0.000044581553,0.00007324825,0.000021863656,0.00013670861,0.000008262655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012791972,0.00044475356,0.041851413,0.00006091877,0.000005897059,0.0000010808643,0.0003985467,0.003149277,0.953469,0.0003638765,0.000018471566,0.00010889181],"study_design_scores_gemma":[0.0017469556,0.000056025063,0.029657675,0.000056863024,0.000008306354,0.0000019283175,0.00004089033,0.0068373615,0.96081144,0.00064875506,0.0000019529755,0.00013187017],"about_ca_topic_score_codex":0.000017914319,"about_ca_topic_score_gemma":0.000022990718,"teacher_disagreement_score":0.012193738,"about_ca_system_score_codex":0.000011365689,"about_ca_system_score_gemma":0.00009874132,"threshold_uncertainty_score":0.49716297},"labels":[],"label_agreement":null},{"id":"W2980672645","doi":"10.1159/000502963","title":"Major Depressive Disorder and Food Hypersensitivity: A Case Report","year":2019,"lang":"en","type":"article","venue":"Neuropsychobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian College of Naturopathic Medicine","funders":"","keywords":"Major depressive disorder; Mood; Medicine; Intervention (counseling); Food hypersensitivity; Psychiatry; Depressive symptoms; Psychology; Immunology; Cognition; Allergy; Food allergy","score_opus":0.017292284549862962,"score_gpt":0.2574768634829245,"score_spread":0.24018457893306153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980672645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98771065,0.0000814218,0.000041377752,0.0006470544,0.0007203486,0.00034687264,0.000021555821,0.000109437155,0.010321293],"genre_scores_gemma":[0.9965735,0.000024300223,0.000032909218,0.0025657767,0.000046777735,0.0000133430485,0.0000028281893,0.000027683433,0.00071286527],"study_design_codex":"bench_or_experimental","study_design_gemma":"case_report","domain_scores_codex":[0.9983872,0.0002256438,0.00018824551,0.0007873069,0.00007493072,0.00033666517],"domain_scores_gemma":[0.9990276,0.00032849543,0.00010060347,0.00043409233,0.000019754021,0.00008944834],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006458033,0.00018101014,0.00021681575,0.00008396017,0.000116963376,0.000026479363,0.00010507557,0.0001034169,0.00009175511],"category_scores_gemma":[0.00033326668,0.00015706645,0.00005576533,0.00017092004,0.00021079784,0.000088959154,0.00010180813,0.00021030327,0.0001816742],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016501876,0.0002584229,0.020407284,0.00004032481,0.000022528446,0.050380245,0.0002837356,0.00000746607,0.9103271,0.0032067418,0.00058062666,0.014320558],"study_design_scores_gemma":[0.007874682,0.0023378513,0.059537236,0.000025224124,0.000039424525,0.821178,0.0005447954,0.00036340993,0.04156143,0.0021161318,0.063176975,0.0012447938],"about_ca_topic_score_codex":0.000020368703,"about_ca_topic_score_gemma":0.00004279935,"teacher_disagreement_score":0.8687656,"about_ca_system_score_codex":0.0000049466184,"about_ca_system_score_gemma":0.000016500844,"threshold_uncertainty_score":0.6404984},"labels":[],"label_agreement":null},{"id":"W2980897804","doi":"10.1016/j.jneuroim.2019.577088","title":"Elevated quinolinic acid levels in cerebrospinal fluid in subacute sclerosing panencephalitis","year":2019,"lang":"en","type":"article","venue":"Journal of Neuroimmunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Ministry of Health, British Columbia; Ministry of Health, Labour and Welfare","keywords":"Subacute sclerosing panencephalitis; Quinolinic acid; Cerebrospinal fluid; Kynurenine; Indoleamine 2,3-dioxygenase; Measles virus; Kynurenine pathway; Medicine; Immunology; Pathological; Pathology; Measles; Biology; Amino acid; Tryptophan; Biochemistry","score_opus":0.045937840386036155,"score_gpt":0.28138538291401205,"score_spread":0.2354475425279759,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980897804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972548,0.0003199288,0.000011242237,0.0009055741,0.0010301778,0.00016095006,0.000004428304,0.000018600605,0.00029431222],"genre_scores_gemma":[0.9983492,0.00038149685,0.000054474327,0.0010398477,0.000037871127,0.0000016635174,3.9635208e-7,0.000024258006,0.00011078923],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9975066,0.0004616489,0.00089017634,0.00033943137,0.000262347,0.00053978484],"domain_scores_gemma":[0.99891424,0.0002765305,0.00042848266,0.00027355787,0.00005227674,0.00005490726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031418784,0.00019570146,0.0004889679,0.0006071613,0.000039614075,0.000043168126,0.00061074743,0.00015212006,0.00023675627],"category_scores_gemma":[0.00061808055,0.00018590617,0.0001235582,0.000736322,0.00017386411,0.00044159638,0.00010384489,0.00083912734,0.0001281698],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023434249,0.00015092922,0.012157028,0.000011316563,0.000004472968,0.00031282802,0.00026550321,0.00005899419,0.9843752,0.0003839357,0.000020877977,0.0020246224],"study_design_scores_gemma":[0.0029324044,0.00083840394,0.87271553,0.00012528828,0.0000030353165,0.0009012386,0.0001276111,0.00008721395,0.12095327,0.0006467589,0.0004898033,0.00017941541],"about_ca_topic_score_codex":0.000023226692,"about_ca_topic_score_gemma":0.000016803215,"teacher_disagreement_score":0.86342186,"about_ca_system_score_codex":0.00009290267,"about_ca_system_score_gemma":0.0001556716,"threshold_uncertainty_score":0.7581034},"labels":[],"label_agreement":null},{"id":"W2981123737","doi":"10.1016/j.bbi.2019.10.016","title":"Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice","year":2019,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa","funders":"National Natural Science Foundation of China","keywords":"Knockout mouse; Dopamine; Dopamine receptor D3; Neuroscience; Dopamine receptor; Receptor; Chemistry; Psychology; Cell biology; Internal medicine; Medicine; Biology","score_opus":0.018588169273545677,"score_gpt":0.27111079003808786,"score_spread":0.2525226207645422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981123737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973046,0.00007764347,0.0000143520465,0.0004798236,0.00045921633,0.0012732765,0.0000908061,0.00007514311,0.00022510359],"genre_scores_gemma":[0.99616134,0.00001930271,0.00006094139,0.0014067416,0.000028625043,0.00019628374,0.000034666267,0.000028681097,0.002063412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983406,0.00026231914,0.00031231588,0.0004807359,0.00019007367,0.00041395894],"domain_scores_gemma":[0.99895394,0.00040259748,0.000095104246,0.00038443896,0.00004928494,0.00011465537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019954208,0.00024386474,0.0002841412,0.00024349958,0.00018501114,0.00010078011,0.00035432793,0.00015408236,0.00021088003],"category_scores_gemma":[0.00048726503,0.00024465338,0.00006754877,0.00041651176,0.00014401964,0.00032350168,0.00021209217,0.00037635711,0.0001247218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015910702,0.00043944985,0.03653811,0.000010959845,0.0000016451717,0.0000056903395,0.00033667262,7.3334917e-7,0.95435774,0.000056926176,0.0005361033,0.0075568487],"study_design_scores_gemma":[0.0015455688,0.00013402241,0.40933144,0.000030561176,0.000008951527,0.0000074826517,0.00028388016,0.0000025994068,0.58391666,0.00001034644,0.0045062182,0.00022228615],"about_ca_topic_score_codex":0.00042390602,"about_ca_topic_score_gemma":0.000078355006,"teacher_disagreement_score":0.37279335,"about_ca_system_score_codex":0.000075483076,"about_ca_system_score_gemma":0.000044930868,"threshold_uncertainty_score":0.9976675},"labels":[],"label_agreement":null},{"id":"W2982018147","doi":"10.1016/bs.acc.2019.07.004","title":"Biomarkers in aggression","year":2019,"lang":"en","type":"review","venue":"Advances in clinical chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Dalhousie University","funders":"","keywords":"Aggression; Psychological intervention; Trait; Genome-wide association study; Psychology; Bioinformatics; Biology; Medicine; Computer science; Developmental psychology; Psychiatry; Genetics; Gene; Genotype","score_opus":0.13366451911756172,"score_gpt":0.47472015241008636,"score_spread":0.34105563329252464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982018147","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017618538,0.9873856,0.0000012631074,0.000016951417,0.00061848795,0.00033915546,0.000020324982,0.000039810526,0.011402272],"genre_scores_gemma":[0.00011036091,0.99901646,0.000053573443,0.0001351059,0.00012316385,0.00004649157,0.000017057333,0.00004018495,0.00045761513],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996573,0.00024231226,0.0014248451,0.0011030114,0.0002500159,0.0004068234],"domain_scores_gemma":[0.9952755,0.003452927,0.00055265735,0.00061437616,0.0000069888256,0.000097546],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004714254,0.00037314414,0.001460993,0.00007181106,0.000019854368,0.000020299107,0.00084160717,0.0006627236,0.00015180722],"category_scores_gemma":[0.0043624956,0.00030390485,0.0004685187,0.0006325848,0.000291033,0.00016100958,0.00021872637,0.0011867573,0.00019912768],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001534967,0.00014546631,0.00012175389,0.009539728,0.0000035211262,0.00006541049,0.0000023510102,0.0000013022709,0.000018968261,0.000005606179,0.000106952764,0.9899736],"study_design_scores_gemma":[0.00050500606,0.000014236412,0.0000049712507,0.024174217,0.0000136663175,0.000010034744,0.0000067054793,0.0000060491207,0.00022429715,0.00026337634,0.9744168,0.00036066925],"about_ca_topic_score_codex":0.000001125626,"about_ca_topic_score_gemma":0.000003270858,"teacher_disagreement_score":0.98961294,"about_ca_system_score_codex":0.00008270237,"about_ca_system_score_gemma":0.00019912788,"threshold_uncertainty_score":0.9999413},"labels":[],"label_agreement":null},{"id":"W2982695288","doi":"10.1503/jpn.180208","title":"Large-scale evidence for an association between low-grade peripheral inflammation and brain structural alterations in major depression in the BiDirect study","year":2019,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Grey matter; Major depressive disorder; Voxel-based morphometry; Insula; Internal medicine; Depression (economics); Body mass index; Inflammation; Medicine; Brain size; Psychology; Gastroenterology; Magnetic resonance imaging; Neuroscience; Amygdala; White matter","score_opus":0.03257646893388833,"score_gpt":0.3282709173923111,"score_spread":0.2956944484584228,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982695288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964373,0.000074146126,0.00012348134,0.0023246754,0.00049874827,0.00052132056,0.0000056227627,0.0000052933888,0.00000942968],"genre_scores_gemma":[0.9991515,0.000023835866,0.00012607858,0.0005447312,0.00011774187,0.0000069327057,2.830388e-7,0.000005161085,0.00002373063],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984025,0.00043605198,0.00035135754,0.00027382377,0.00033543984,0.00020085495],"domain_scores_gemma":[0.9989742,0.00055031804,0.00028440228,0.00011556195,0.000023549335,0.00005196047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011573564,0.00009921507,0.00015091518,0.00015004816,0.00019901778,0.00018797084,0.000260495,0.000042226646,0.0000023599766],"category_scores_gemma":[0.00068897125,0.00006904837,0.00003306991,0.00037956002,0.00003842387,0.001229434,0.00002865371,0.00023193598,2.2022861e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007713346,0.000098428274,0.8745918,0.000018109418,6.0538775e-7,0.0000011828494,0.002867031,0.00014565037,0.121787466,0.000065519016,0.000021808151,0.00032523708],"study_design_scores_gemma":[0.0014540602,0.0006844523,0.9895186,0.000064089814,0.0000054519646,0.000018376191,0.0013621539,0.0035465958,0.0024626383,0.00076351844,0.000030383384,0.000089725174],"about_ca_topic_score_codex":0.0000058127102,"about_ca_topic_score_gemma":0.0002861562,"teacher_disagreement_score":0.119324826,"about_ca_system_score_codex":0.000024477444,"about_ca_system_score_gemma":0.000056560002,"threshold_uncertainty_score":0.2815711},"labels":[],"label_agreement":null},{"id":"W2982773615","doi":"10.1016/j.jad.2019.10.037","title":"Differences in the immune-inflammatory profiles of unipolar and bipolar depression","year":2019,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":91,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"National Health and Medical Research Council; Fundação de Amparo à Pesquisa do Estado de São Paulo; National Alliance for Research on Schizophrenia and Depression","keywords":"Major depressive disorder; Depression (economics); Bipolar disorder; Logistic regression; Internal medicine; Immune system; Psychology; Melancholia; Tumor necrosis factor alpha; Medicine; Oncology; Immunology","score_opus":0.008984917789110104,"score_gpt":0.23582926322372347,"score_spread":0.22684434543461338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982773615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950718,0.003769618,0.000030506319,0.00017007337,0.00013868518,0.00030121647,0.000002566689,0.000004657229,0.0005108323],"genre_scores_gemma":[0.9990699,0.00080710294,0.000016491538,0.00006822738,0.000013525391,0.0000030692613,1.4837845e-7,0.000008927435,0.000012554102],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99868786,0.0004101449,0.000282386,0.00014720422,0.00031287447,0.00015953378],"domain_scores_gemma":[0.9987362,0.00071974046,0.00034079613,0.00013913892,0.000033651348,0.000030481113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041836093,0.00012293337,0.0002433996,0.00020780232,0.000054315162,0.000024495872,0.00032148694,0.000055864704,0.000021396165],"category_scores_gemma":[0.000451418,0.00007335855,0.00009161882,0.00028117187,0.00018503003,0.00027343724,0.000045446544,0.00028746683,0.0000026722287],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000169631,0.0002207312,0.6500888,0.00008184682,0.00001566628,0.0000063318357,0.0027832333,0.00001721144,0.32569385,0.0010255091,0.0000274839,0.01986971],"study_design_scores_gemma":[0.0012980573,0.00039169512,0.89837825,0.00012358734,0.000008356388,0.000021464337,0.00372122,0.00007406564,0.09408989,0.0014373325,0.00034001318,0.00011609047],"about_ca_topic_score_codex":0.000032690732,"about_ca_topic_score_gemma":0.000038695118,"teacher_disagreement_score":0.24828942,"about_ca_system_score_codex":0.000013087435,"about_ca_system_score_gemma":0.000047007234,"threshold_uncertainty_score":0.2991475},"labels":[],"label_agreement":null},{"id":"W2982939998","doi":"10.31887/dcns.2017.19.1/rmcintyre","title":"Inflammation: opportunities for treatment stratification among individuals diagnosed with mood disorders","year":2017,"lang":"en","type":"article","venue":"Dialogues in Clinical Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Mental Health; H. Lundbeck A/S; Sunovion; Pfizer; Brain and Behavior Research Foundation; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Mood; Mood disorders; Anhedonia; Disease; Inflammation; Medicine; Psychology; Psychiatry; Clinical psychology; Immunology; Anxiety; Internal medicine; Schizophrenia (object-oriented programming)","score_opus":0.241837178532663,"score_gpt":0.38486459322736044,"score_spread":0.14302741469469743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982939998","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915086,0.0000044622593,0.0004308719,0.0029920344,0.000702367,0.0010825774,0.00007054805,0.00008275845,0.0031257805],"genre_scores_gemma":[0.998105,0.00048477307,0.00018237933,0.00041931798,0.000121255456,0.00033378223,0.00001281546,0.000019771505,0.00032089135],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99756104,0.0002199973,0.0006152373,0.0008487142,0.0003436515,0.0004113359],"domain_scores_gemma":[0.9967901,0.0017156015,0.0004840882,0.00081928,0.000032584107,0.00015835873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058893376,0.00022774396,0.00030951964,0.00010718217,0.0006885653,0.00046238472,0.0009628318,0.00010742212,0.0000060476773],"category_scores_gemma":[0.006458524,0.00017883719,0.00011164466,0.00014398214,0.0021014104,0.00091687345,0.00009115239,0.00012312554,0.0000058401893],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022006509,0.0014858647,0.8289608,0.000042813615,0.000005768157,0.00004613743,0.001202112,0.0003650438,0.008213039,0.017759258,0.00014536812,0.14155373],"study_design_scores_gemma":[0.002408801,0.0011368825,0.9802678,0.00003558974,0.000009063475,0.0000016263019,0.00020187483,0.0012098337,0.0069002905,0.005341669,0.0021694468,0.00031711045],"about_ca_topic_score_codex":0.00004560758,"about_ca_topic_score_gemma":0.0016272656,"teacher_disagreement_score":0.15130702,"about_ca_system_score_codex":0.00002537998,"about_ca_system_score_gemma":0.0001433627,"threshold_uncertainty_score":0.77427346},"labels":[],"label_agreement":null},{"id":"W2985907841","doi":"10.1523/jneurosci.0845-19.2019","title":"DNA Methylation within the Amygdala Early in Life Increases Susceptibility for Depression and Anxiety Disorders","year":2019,"lang":"en","type":"letter","venue":"Journal of Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Epigenetics; Amygdala; Anxiety; Depression (economics); DNA methylation; Psychology; Psychiatry; Neuroscience; Clinical psychology; Genetics; Gene; Biology; Gene expression","score_opus":0.027035312121274482,"score_gpt":0.2727173223462308,"score_spread":0.24568201022495634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2985907841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.910544,0.00016738266,0.00031965764,0.086628735,0.0014378281,0.0007850704,0.000030998064,0.000017437498,0.000068906775],"genre_scores_gemma":[0.82602197,0.00030334707,0.00006557176,0.1731072,0.00032853143,0.000009968322,8.809338e-7,0.000028090963,0.00013440943],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99684906,0.000583522,0.00068568345,0.00066866097,0.0008191638,0.00039390955],"domain_scores_gemma":[0.9968492,0.0015705483,0.0010145638,0.00040171287,0.000072583025,0.000091413676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010874924,0.00029165682,0.00040687155,0.0002806434,0.00023161211,0.00023864588,0.0009469554,0.0002518164,0.0000042994775],"category_scores_gemma":[0.0074631614,0.00018683373,0.00019032737,0.00053665624,0.0005654719,0.0006715184,0.00015619001,0.0014183391,0.0000015920477],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005771923,0.00036902423,0.044357065,0.0003875644,0.0000067023993,0.00007122668,0.0011710055,0.0006160391,0.82463694,0.000088350775,0.12072618,0.006992716],"study_design_scores_gemma":[0.004834702,0.0021023906,0.703524,0.0005407174,0.00009039867,0.00039232135,0.00028623972,0.005624549,0.03166895,0.0067530912,0.24271207,0.0014706042],"about_ca_topic_score_codex":0.0000378248,"about_ca_topic_score_gemma":0.00003569667,"teacher_disagreement_score":0.792968,"about_ca_system_score_codex":0.000042263855,"about_ca_system_score_gemma":0.00026458557,"threshold_uncertainty_score":0.893464},"labels":[],"label_agreement":null},{"id":"W2989382642","doi":"10.1016/j.biopsych.2019.10.014","title":"Cell Type–Specific Methylome-wide Association Studies Implicate Neurotrophin and Innate Immune Signaling in Major Depressive Disorder","year":2019,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Royal Ottawa Mental Health Centre; McGill University; Douglas Mental Health University Institute","funders":"Victorian Brain Bank; National Health and Medical Research Council; Leids Universitair Medisch Centrum; ZonMw; Rijksuniversiteit Groningen; Nederlandse Hersenbank; National Institutes of Health; Stanley Medical Research Institute; Universiteit Leiden; National Institute of Mental Health; Parkinson’s Victoria","keywords":"Innate immune system; DNA methylation; Epigenetics; Biology; Immune system; Immunology; Signal transduction; Neurotrophin; Neuroscience; Genetics; Gene; Receptor; Gene expression","score_opus":0.03421180690287987,"score_gpt":0.2805331479926046,"score_spread":0.24632134108972473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2989382642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98547524,0.010170661,0.000010172196,0.00257353,0.0008162869,0.00042132728,0.000008536885,0.000075177646,0.00044903863],"genre_scores_gemma":[0.99529105,0.0019727352,0.00019409298,0.0022330033,0.000059435133,0.000023743021,0.0000033915871,0.000016447124,0.00020611346],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99818754,0.00029173668,0.000355467,0.00063135166,0.00014962064,0.00038429874],"domain_scores_gemma":[0.9984575,0.0010359812,0.00020695111,0.00021308883,0.000032525957,0.000053932512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023065293,0.00021194448,0.000324081,0.00009712889,0.000108260036,0.000041213178,0.00024163914,0.0001684847,0.00006804437],"category_scores_gemma":[0.0007444161,0.00015516415,0.000073405055,0.0003988287,0.00008801563,0.00009626835,0.00016155258,0.0003186644,0.00015200587],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016045583,0.0001929896,0.41697174,0.000035166562,0.000011624118,0.000003866787,0.00012062075,0.0000404385,0.58031666,0.0008025647,0.0008785041,0.0004653573],"study_design_scores_gemma":[0.0039956328,0.0006172966,0.9278197,0.000055980243,0.000012164852,0.000002921356,0.0007926825,0.000044326058,0.038411867,0.02146203,0.0060585937,0.0007267906],"about_ca_topic_score_codex":0.000008529625,"about_ca_topic_score_gemma":0.0000039521196,"teacher_disagreement_score":0.5419048,"about_ca_system_score_codex":0.00004102214,"about_ca_system_score_gemma":0.00001821023,"threshold_uncertainty_score":0.63274103},"labels":[],"label_agreement":null},{"id":"W2989583641","doi":"10.22215/etd/2019-13740","title":"Novel Treatment Strategies for Major Depressive Disorder: Investigating Ketamine’s Antidepressant Effects and the Role of the c-Jun N-Terminal Kinase Pathway","year":2019,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Ketamine; Antidepressant; Monoaminergic; NMDA receptor; Pharmacology; Monoamine neurotransmitter; Corticosterone; Medicine; Psychology; Neuroscience; Hippocampus; Internal medicine; Receptor; Hormone; Serotonin","score_opus":0.012182672581894694,"score_gpt":0.2492048445312531,"score_spread":0.2370221719493584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2989583641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99047214,0.0013953127,0.000107270775,0.00008271635,0.00036617284,0.0029421116,0.00012908592,0.000039021383,0.0044661984],"genre_scores_gemma":[0.9963368,0.0000950059,0.000118176635,0.00015811528,0.000038234877,0.00044080932,0.000047780573,0.000049006772,0.0027160768],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982722,0.00015996039,0.000358911,0.00059508,0.00029816915,0.0003156707],"domain_scores_gemma":[0.9973377,0.0015741014,0.0004981156,0.00048333776,0.000052695606,0.00005402928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009775113,0.00042872236,0.0004967795,0.00006850066,0.00034428985,0.00015273392,0.0004589118,0.00016958253,0.0000074787094],"category_scores_gemma":[0.0005396956,0.00021137326,0.00026122972,0.00014825679,0.0003889869,0.00015918147,0.000071877854,0.0001752647,0.000001912076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048016154,0.0003164086,0.0010854236,0.0011428039,0.000079021665,0.000003986444,0.0047846353,0.0000733235,0.9165954,0.041680545,0.000024316487,0.033733964],"study_design_scores_gemma":[0.007403836,0.00029262423,0.010959737,0.0003856361,0.00016430479,0.0000150132855,0.0076407646,0.0026010296,0.9634263,0.0064119385,0.0002927704,0.00040605015],"about_ca_topic_score_codex":0.00047353955,"about_ca_topic_score_gemma":0.00060695264,"teacher_disagreement_score":0.04683088,"about_ca_system_score_codex":0.00001765363,"about_ca_system_score_gemma":0.00024057609,"threshold_uncertainty_score":0.86195517},"labels":[],"label_agreement":null},{"id":"W2990176558","doi":"10.3389/fpsyt.2019.00870","title":"Editorial: Neurobiology, Clinical Course, and Therapeutic Approaches of Treatment-Resistant Schizophrenia: Toward an Integrated View","year":2019,"lang":"en","type":"editorial","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia (object-oriented programming); Psychiatry; Psychology; Psychotherapist; Neuroscience; Medicine","score_opus":0.03863369640974888,"score_gpt":0.3102620811138025,"score_spread":0.2716283847040536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990176558","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0041239057,0.005781986,0.000080925274,0.00019414023,0.9881763,0.00084137643,0.0005386987,0.000092643015,0.00017001084],"genre_scores_gemma":[0.0042231465,0.005163221,0.0027243278,0.0001554909,0.98706174,0.00006500857,0.00024006297,0.00014568774,0.00022134405],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99537367,0.0011153813,0.0010634945,0.0014760167,0.00042677022,0.000544679],"domain_scores_gemma":[0.997678,0.0006364267,0.0006076607,0.0008455499,0.00006380207,0.00016859968],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00054163183,0.00069269555,0.00149731,0.00029363242,0.000077429104,0.00007481247,0.0008599822,0.0017942254,0.000013130665],"category_scores_gemma":[0.0004447344,0.00055576523,0.0003088851,0.00043921554,0.0008465979,0.000133477,0.000090701615,0.0014136524,0.000008154922],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018269771,0.00085531396,0.0017863436,0.00019146159,0.000101213176,0.0000015969053,0.0000986851,0.0000037772545,0.0000614039,0.00019919901,0.9862836,0.008590401],"study_design_scores_gemma":[0.006016669,0.0030030797,0.0004935662,0.00022103639,0.00018578338,0.0000013746717,0.0006733454,0.000120190256,0.00003628393,0.0023039759,0.98623747,0.0007072439],"about_ca_topic_score_codex":0.000053876,"about_ca_topic_score_gemma":0.00009328388,"teacher_disagreement_score":0.007883158,"about_ca_system_score_codex":0.00011176821,"about_ca_system_score_gemma":0.0017183612,"threshold_uncertainty_score":0.9996894},"labels":[],"label_agreement":null},{"id":"W2990789324","doi":"10.1080/15622975.2019.1696474","title":"The impact of sample processing on inflammatory markers in serum: Lessons learned","year":2019,"lang":"en","type":"article","venue":"The World Journal of Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biobank; Cytokine; Biomarker; Medicine; Interleukin 6; Interleukin 18; Immunology; Internal medicine; Bioinformatics; Biology","score_opus":0.05089325839945553,"score_gpt":0.3390600479806851,"score_spread":0.2881667895812296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990789324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894836,0.00040329868,0.0000047868384,0.0072406316,0.00034458237,0.00014489751,0.000004936675,0.0000089921905,0.0023642853],"genre_scores_gemma":[0.9990434,0.0001870943,0.000053822972,0.00049959123,0.000078642704,0.0000010563158,1.3105586e-7,0.000007890777,0.00012834753],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99855137,0.0003876527,0.00043311043,0.00015081068,0.00020783776,0.00026923025],"domain_scores_gemma":[0.9981387,0.0011000398,0.0004720501,0.00020821729,0.000025811883,0.000055150926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008573645,0.00013202126,0.00022188979,0.000116325995,0.00012991228,0.000035646175,0.00063082715,0.000053713473,0.00011803329],"category_scores_gemma":[0.00043382103,0.00005339308,0.00023170037,0.0004478488,0.0002654419,0.0000726434,0.000051307725,0.0005445712,0.000015545796],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00801524,0.0010032572,0.74181414,0.00006682534,0.00008205012,0.000012905392,0.0005533929,0.0041393056,0.08544849,0.018975379,0.005430665,0.13445833],"study_design_scores_gemma":[0.0014774719,0.0010357235,0.95239526,0.00022863493,0.000005221407,0.00002527594,0.00064891303,0.00017313151,0.0016367836,0.0408145,0.0013818478,0.00017723822],"about_ca_topic_score_codex":0.000006376876,"about_ca_topic_score_gemma":0.000037836544,"teacher_disagreement_score":0.2105811,"about_ca_system_score_codex":0.00003547711,"about_ca_system_score_gemma":0.00014485486,"threshold_uncertainty_score":0.23659211},"labels":[],"label_agreement":null},{"id":"W2990932459","doi":"10.1177/0004867419888027","title":"Differential biomarker signatures in unipolar and bipolar depression: A machine learning approach","year":2019,"lang":"en","type":"article","venue":"Australian & New Zealand Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Biomarker; Depression (economics); Bipolar disorder; Differential (mechanical device); Psychology; Artificial intelligence; Computer science; Neuroscience; Physics; Biology; Cognition; Genetics","score_opus":0.01707402169948979,"score_gpt":0.2554910535589782,"score_spread":0.23841703185948843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990932459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99494165,0.0019087121,0.000034023058,0.0018643796,0.0008089568,0.00013741213,0.000004951677,0.000017078319,0.00028282162],"genre_scores_gemma":[0.9934296,0.00027230024,0.0006394972,0.00019841279,0.00019515037,5.1117746e-7,0.000001939455,0.00002354761,0.0052390583],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99848044,0.00019228131,0.0004027242,0.00028910994,0.00031077664,0.00032465317],"domain_scores_gemma":[0.99926,0.00006380843,0.00028945017,0.00014653946,0.000014871948,0.0002253123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015406878,0.00020708922,0.00029989827,0.00030650245,0.000068920504,0.000086349915,0.00028363892,0.00015438537,0.00039570298],"category_scores_gemma":[0.00004975123,0.00015513324,0.00011622265,0.0002979814,0.000057382327,0.00024796036,0.000047720492,0.0007877458,0.000008826498],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00061085843,0.00039490763,0.87298375,0.000077636265,0.00003808087,0.000033981752,0.00043962867,0.0003084026,0.10443399,0.00033925023,0.013299356,0.007040156],"study_design_scores_gemma":[0.012129409,0.0008997383,0.8812142,0.00042956337,0.000063944804,0.0006950021,0.00046222907,0.0009471128,0.00881276,0.0025980403,0.0909732,0.00077481475],"about_ca_topic_score_codex":0.000078338926,"about_ca_topic_score_gemma":0.000033780678,"teacher_disagreement_score":0.09562123,"about_ca_system_score_codex":0.000012700788,"about_ca_system_score_gemma":0.00009215519,"threshold_uncertainty_score":0.63261503},"labels":[],"label_agreement":null},{"id":"W2991093702","doi":"10.1016/j.bbi.2019.11.020","title":"Prenatal low-dose penicillin results in long-term sex-specific changes to murine behaviour, immune regulation, and gut microbiota","year":2019,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University","funders":"Office of Naval Research; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Penicillin; Immune system; Gut flora; Term (time); Antibiotics; Immunology; Microbiology; Medicine; Biology","score_opus":0.021142161757365354,"score_gpt":0.26331124402999184,"score_spread":0.24216908227262648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2991093702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99695265,0.00039621576,0.0000029349508,0.00090245856,0.00021279894,0.0011521509,0.00016628776,0.00006696416,0.00014754364],"genre_scores_gemma":[0.9963387,0.00022517394,0.000054634034,0.0004021887,0.000026863394,0.000046808414,0.000097751086,0.00003534335,0.0027724851],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980283,0.00023380283,0.00041415033,0.00066870946,0.00020273576,0.0004523392],"domain_scores_gemma":[0.99878097,0.00021465447,0.000113089445,0.00070947537,0.000036350386,0.00014548254],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038920503,0.0002995916,0.00032529957,0.0002804414,0.00020081708,0.00013906271,0.00035626156,0.00014835518,0.00015640237],"category_scores_gemma":[0.00013545911,0.00029902664,0.000051568528,0.00038979365,0.00019596907,0.0002418631,0.00039823976,0.00036384695,0.00004410304],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029193715,0.0004121527,0.03810702,0.00005238343,0.0000017860958,0.000027577767,0.0014837253,0.0000014841846,0.9468078,0.000035325847,0.00021607438,0.012562754],"study_design_scores_gemma":[0.0025191735,0.00019744899,0.8454799,0.0001262105,0.00000577675,0.000056146444,0.00017492012,0.00000451862,0.15078811,0.00000906008,0.00032003215,0.00031867332],"about_ca_topic_score_codex":0.00026356737,"about_ca_topic_score_gemma":0.00032737994,"teacher_disagreement_score":0.8073729,"about_ca_system_score_codex":0.000046667454,"about_ca_system_score_gemma":0.000025307383,"threshold_uncertainty_score":0.9999462},"labels":[],"label_agreement":null},{"id":"W2991319024","doi":"10.1016/j.jad.2019.11.108","title":"Reverse translation of major depressive disorder symptoms: A framework for the behavioural phenotyping of putative biomarkers","year":2019,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; McGill University; Simon Fraser University; Royal Ottawa Mental Health Centre; University of Guelph; Centre for Addiction and Mental Health; University of Calgary; Queen's University; McMaster University; University of Toronto; University Health Network; St. Michael's Hospital; University of British Columbia","funders":"Government of Ontario; Ontario Brain Institute","keywords":"Major depressive disorder; Biomarker; Psychology; Clinical psychology; Rating scale; Anxiety; Depression (economics); Cognition; Clinical significance; Beck Depression Inventory; Psychiatry; Medicine; Developmental psychology; Internal medicine; Biology","score_opus":0.05431353059625012,"score_gpt":0.34842743615929295,"score_spread":0.29411390556304284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2991319024","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008461696,0.9438009,0.050546166,0.00015002889,0.00083962036,0.0033561692,0.00035039213,0.000013547711,0.00009699522],"genre_scores_gemma":[0.028366392,0.97034556,0.0008738638,0.000063088424,0.000075761665,0.000115512805,0.000014807852,0.00012550027,0.000019492772],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99662167,0.0007042955,0.0012542113,0.00045098757,0.0005780129,0.0003908413],"domain_scores_gemma":[0.98626554,0.009363595,0.0036551852,0.00036971047,0.0002668059,0.00007916739],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00054025784,0.000550182,0.0018713456,0.0005266014,0.00016145971,0.000034301996,0.0008318381,0.00037255726,0.000030274527],"category_scores_gemma":[0.0025546511,0.00036272677,0.001895668,0.0009762426,0.0005672848,0.0003476322,0.00006209615,0.0007361187,0.000002652581],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035105017,0.000309536,0.00009674529,0.005280655,0.0008317702,0.0000020546129,0.0017163365,0.00011239093,0.00014836127,0.0008435088,0.000072036666,0.99023557],"study_design_scores_gemma":[0.070644155,0.01841591,0.0055472245,0.1979497,0.06958945,0.00069117366,0.051382724,0.0046392474,0.013129853,0.091140196,0.46342394,0.013446431],"about_ca_topic_score_codex":0.000057467812,"about_ca_topic_score_gemma":0.00003283112,"teacher_disagreement_score":0.9767891,"about_ca_system_score_codex":0.000106649786,"about_ca_system_score_gemma":0.00044833592,"threshold_uncertainty_score":0.99988246},"labels":[],"label_agreement":null},{"id":"W2992574246","doi":"10.1038/s41598-019-54812-9","title":"GWAS studies reveal a possible genetic link between cancer and suicide attempt","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Umeå Universitet; Karolinska Institutet","keywords":"Genome-wide association study; Cancer; Incidence (geometry); Population; Genetic association; Gene; Medicine; Biology; Genetics; Bioinformatics; Single-nucleotide polymorphism; Genotype; Environmental health","score_opus":0.0518264930500918,"score_gpt":0.3214506647414236,"score_spread":0.2696241716913318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2992574246","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915031,0.0019055348,0.0000040926925,0.0009852092,0.003961463,0.00040592343,0.0000056926224,0.00008020294,0.0011487511],"genre_scores_gemma":[0.97704357,0.00007547494,0.00012147294,0.00021470913,0.00015069051,0.00002151901,0.0000025633483,0.000017750534,0.022352252],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975749,0.000056564808,0.00039413825,0.0010866051,0.000481067,0.0004067221],"domain_scores_gemma":[0.99878746,0.00013022182,0.00021883824,0.00066394807,0.00007133546,0.00012818065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005039571,0.00016538418,0.0002640307,0.00014943589,0.00031426275,0.0002448718,0.0001623832,0.000056765657,0.00010359615],"category_scores_gemma":[0.0003525591,0.00013695586,0.00006239961,0.00052788114,0.00046694663,0.00018472357,0.0001788575,0.0001225536,0.00009683165],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000095622845,0.000027884604,0.5230308,0.00017101283,0.000028166396,0.00034420608,0.0014689972,0.00006707867,0.43080157,0.000052328804,0.0162861,0.027712302],"study_design_scores_gemma":[0.0007068596,0.00013202013,0.3508986,0.00032044837,0.000049966504,0.00030020677,0.000497089,0.00007057538,0.5640534,0.021400984,0.060727682,0.00084216835],"about_ca_topic_score_codex":0.00004652515,"about_ca_topic_score_gemma":0.0000369622,"teacher_disagreement_score":0.17213222,"about_ca_system_score_codex":0.000036584563,"about_ca_system_score_gemma":0.00012486363,"threshold_uncertainty_score":0.5584898},"labels":[],"label_agreement":null},{"id":"W2993013368","doi":"","title":"A comparison of the frequency of physical disorders in patients with and without associated Conduct Disorder","year":2012,"lang":"en","type":"article","venue":"Journal of undergraduate research in Alberta","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Abnormality; Medicine; Population; Conduct disorder; Internal medicine; Blood pressure; Endocrinology; Physiology; Psychiatry","score_opus":0.06678733321658212,"score_gpt":0.3756124721077652,"score_spread":0.3088251388911831,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2993013368","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939887,0.0000914628,0.0000033160347,0.005058145,0.00005193257,0.0003081404,0.0000033217043,0.0000013489857,0.0004936613],"genre_scores_gemma":[0.9998431,0.000044781653,0.000022258439,0.000015129176,0.000011014562,0.0000032482253,4.6733373e-7,0.000016438926,0.00004354499],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9969893,0.0008793994,0.00049721444,0.0001540564,0.0010230602,0.00045698407],"domain_scores_gemma":[0.9979375,0.0012050989,0.00042686952,0.00018980821,0.00013378546,0.00010696298],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007017515,0.00013261687,0.0004299702,0.0003204897,0.000062765605,0.00001717953,0.00038713528,0.000057028505,0.0000025474585],"category_scores_gemma":[0.001818139,0.000079372534,0.00007391714,0.0011042401,0.00064575125,0.00034744525,0.00010851362,0.00070020754,8.8001735e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015250967,0.0022370126,0.9874896,0.00003879901,0.000017048407,2.2266318e-7,0.000955417,0.000042104188,0.0046069985,0.0038575174,0.000030333487,0.00057243323],"study_design_scores_gemma":[0.0041073193,0.000754401,0.97048074,0.00031507245,0.000008860634,0.0000016083015,0.00032729938,0.00033481934,0.006030576,0.017475089,0.000033063265,0.00013115119],"about_ca_topic_score_codex":0.0009908106,"about_ca_topic_score_gemma":0.00328329,"teacher_disagreement_score":0.017008863,"about_ca_system_score_codex":0.00007267358,"about_ca_system_score_gemma":0.00013013359,"threshold_uncertainty_score":0.3236718},"labels":[],"label_agreement":null},{"id":"W2994914973","doi":"10.1016/j.bbih.2019.100027","title":"Retinal-glia ischemia and inflammation induced by chronic stress: The SABPA study","year":2019,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; North-West University; South African Medical Research Council; National Research Foundation; Heart and Stroke Foundation of Canada","keywords":"Medicine; Ischemia; Glial fibrillary acidic protein; Internal medicine; Retinal; Cardiology; Pathology; Endocrinology; Ophthalmology; Immunohistochemistry","score_opus":0.02948425453626303,"score_gpt":0.3130867752925413,"score_spread":0.2836025207562783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2994914973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930964,0.0002942177,0.0000025212219,0.0039067143,0.000183822,0.0021091732,0.000035972087,0.00011083429,0.00026035385],"genre_scores_gemma":[0.99802065,0.00007430822,0.000009238147,0.0011751386,0.00004417147,0.000100706195,0.000025339154,0.000032464326,0.0005179809],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9973323,0.0009281842,0.00041295352,0.0004433752,0.00038912278,0.00049408036],"domain_scores_gemma":[0.9983287,0.0004266489,0.00026383175,0.00081369124,0.000031603427,0.00013552835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082547957,0.00024139008,0.00026582732,0.00008236405,0.0006205595,0.00012368168,0.00052599545,0.00009967768,0.00016359765],"category_scores_gemma":[0.00030900596,0.00019553778,0.000049367227,0.00037035125,0.00014806628,0.00026089174,0.00021538117,0.0007231709,0.000084276006],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052686395,0.00061344804,0.016427152,0.00009493165,0.000006788661,0.0000032647854,0.0061419033,0.0000013099888,0.94821256,0.0002085233,0.0018775222,0.026359905],"study_design_scores_gemma":[0.0047390466,0.0029217072,0.7804402,0.00015698212,0.00004200174,0.000027702457,0.013076207,0.00007549208,0.19031778,0.0000788939,0.007367054,0.00075690617],"about_ca_topic_score_codex":0.0012836767,"about_ca_topic_score_gemma":0.00041107013,"teacher_disagreement_score":0.76401305,"about_ca_system_score_codex":0.00014933657,"about_ca_system_score_gemma":0.00027720848,"threshold_uncertainty_score":0.79738},"labels":[],"label_agreement":null},{"id":"W2995269564","doi":"10.1016/j.ynstr.2019.100204","title":"Acute sleep deprivation during pregnancy in rats: Rapid elevation of placental and fetal inflammation and kynurenic acid","year":2019,"lang":"en","type":"article","venue":"Neurobiology of Stress","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Kynurenic acid; Kynurenine; Endocrinology; Internal medicine; Fetus; Kynurenine pathway; Pregnancy; Sleep deprivation; Offspring; Proinflammatory cytokine; Medicine; Corticosterone; Placenta; Inflammation; Biology; NMDA receptor; Circadian rhythm; Tryptophan; Hormone; Amino acid","score_opus":0.008242990464605847,"score_gpt":0.21724229688621102,"score_spread":0.20899930642160516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995269564","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9993521,0.00009333066,0.000006001625,0.000073631236,0.00008630173,0.00027366288,0.00001892225,0.000013330241,0.000082750295],"genre_scores_gemma":[0.9996561,0.0002652985,0.000024004696,0.000012567519,0.000006543857,0.000005467795,0.000011411068,0.000006068998,0.0000125320985],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992798,0.00008260004,0.00022015035,0.00024376133,0.000057030076,0.00011665735],"domain_scores_gemma":[0.9996275,0.00007961522,0.00016128519,0.000102187725,0.000013429997,0.000016003894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000027322247,0.00008681962,0.00014650913,0.00012396064,0.000023246672,0.00000532911,0.00007641072,0.00007502781,0.000012860682],"category_scores_gemma":[0.00006394896,0.00008444231,0.000016655556,0.00011996804,0.00012859137,0.00018983036,0.000057467256,0.00008670585,0.0000013232005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000108900196,0.000024400924,0.05291751,0.00008296145,0.0000032215248,0.0000011212509,0.00020192438,0.000024752988,0.943555,0.00016312543,4.701673e-7,0.0029166029],"study_design_scores_gemma":[0.0009435921,0.000104639425,0.24666561,0.00006556703,0.0000029821495,0.0000068307772,0.000039124476,0.00015210417,0.751913,0.000054216238,0.0000012210081,0.000051124774],"about_ca_topic_score_codex":0.000003259442,"about_ca_topic_score_gemma":0.000011511696,"teacher_disagreement_score":0.1937481,"about_ca_system_score_codex":0.0000069125763,"about_ca_system_score_gemma":0.000007340708,"threshold_uncertainty_score":0.34434578},"labels":[],"label_agreement":null},{"id":"W2996484739","doi":"10.1038/s41598-019-55539-3","title":"Allergen-induced anxiety-like behavior is associated with disruption of medial prefrontal cortex - amygdala circuit","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"Tarbiat Modares University; Iran National Science Foundation; National Science Foundation","keywords":"Amygdala; Prefrontal cortex; Neuroscience; Anxiety; Psychology; Medicine; Psychiatry; Cognition","score_opus":0.02268008011822434,"score_gpt":0.24715455326606087,"score_spread":0.22447447314783653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2996484739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898371,0.000014320057,0.000009132729,0.000026685466,0.006475365,0.0007725696,0.000020024147,0.00010328265,0.0027414972],"genre_scores_gemma":[0.99379843,0.0000036137235,0.000012754871,0.00007538181,0.000026398573,0.000033406042,0.000055070588,0.000029143079,0.005965817],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966187,0.00008193354,0.00052408077,0.0011394883,0.0011970021,0.00043881332],"domain_scores_gemma":[0.99823725,0.000046309204,0.00059224124,0.0008469003,0.0001257347,0.00015158941],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005407347,0.00021354792,0.00029195548,0.00016171408,0.00019554325,0.00013643205,0.0002552404,0.0001294596,0.00093829475],"category_scores_gemma":[0.00022397556,0.00018020766,0.00013693873,0.0007171162,0.00032400928,0.00034644784,0.000081641614,0.000167127,0.0000770277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018699595,0.00030951342,0.025200756,0.000010830973,0.000009039865,0.00012208027,0.0008535801,0.0000029060234,0.9712198,0.00002618833,0.0013361254,0.00089050154],"study_design_scores_gemma":[0.0009575012,0.0002619765,0.3132503,0.00007564737,0.0000449284,0.00026223544,0.00028004358,0.00009630541,0.6805879,0.00050000835,0.0031791627,0.00050398783],"about_ca_topic_score_codex":0.000029593797,"about_ca_topic_score_gemma":0.000088655506,"teacher_disagreement_score":0.2906319,"about_ca_system_score_codex":0.000071104994,"about_ca_system_score_gemma":0.00021570131,"threshold_uncertainty_score":0.99997497},"labels":[],"label_agreement":null},{"id":"W2996844137","doi":"10.1186/s13041-019-0539-z","title":"Anxiolytic effects of the flavonoid luteolin in a mouse model of acute colitis","year":2019,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Azrieli Foundation; Israel Science Foundation; Canada Research Chairs","keywords":"Luteolin; Anxiolytic; Elevated plus maze; Pharmacology; Open field; Antidepressant; Anxiogenic; Sedative; Medicine; Anxiety; Internal medicine; Flavonoid; Psychiatry; Chemistry; Biochemistry","score_opus":0.0060682377460333555,"score_gpt":0.21870106509401974,"score_spread":0.2126328273479864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2996844137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974052,0.000026835734,0.00060033234,0.00037403376,0.00006894399,0.00059063174,0.000028313241,0.000016850605,0.0008889069],"genre_scores_gemma":[0.996867,0.0000066666935,0.00011103653,0.0018121855,0.0000027182916,0.000015468386,7.584287e-7,0.000020992073,0.0011631446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988392,0.00018395462,0.00021590453,0.00027348363,0.00024825722,0.00023917478],"domain_scores_gemma":[0.9992107,0.00016394666,0.00009910336,0.00047468173,0.000014386812,0.00003718036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009949013,0.00012325961,0.00021538942,0.00009221453,0.000016592881,0.000007920033,0.00042090876,0.000068660054,0.000010063576],"category_scores_gemma":[0.0003269568,0.00010017898,0.00012984866,0.0003319595,0.00012204534,0.000050825267,0.000132898,0.00012708084,0.0000141500195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025961786,0.00007820536,0.00010842188,0.00009263345,0.0000066084835,0.000007700092,0.0002746567,0.0026798954,0.99227345,0.0042378074,0.00006484366,0.00014980104],"study_design_scores_gemma":[0.0010311062,0.000054591703,0.0010419971,0.000046233214,0.000005351409,0.0000015878392,0.000010615185,0.021337252,0.97474366,0.0016191403,0.000006893616,0.000101566686],"about_ca_topic_score_codex":0.000025347645,"about_ca_topic_score_gemma":0.000009709597,"teacher_disagreement_score":0.018657357,"about_ca_system_score_codex":0.000021125194,"about_ca_system_score_gemma":0.000069486705,"threshold_uncertainty_score":0.40851802},"labels":[],"label_agreement":null},{"id":"W2997367341","doi":"10.1016/j.bbih.2019.100034","title":"Neuroinflammation and glial cell activation in mental disorders","year":2019,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Neuroinflammation; Kynurenine pathway; Neuroscience; Microglia; Monoaminergic; Kynurenine; Context (archaeology); Bipolar disorder; Schizophrenia (object-oriented programming); Inflammation; Psychology; Biology; Medicine; Psychiatry; Immunology; Internal medicine; Cognition; Serotonin; Receptor","score_opus":0.020270951692433942,"score_gpt":0.2860175878755615,"score_spread":0.26574663618312755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2997367341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99443275,0.000021707177,0.000013338014,0.00333513,0.00022780383,0.0011708534,0.000011284481,0.000074439326,0.0007127221],"genre_scores_gemma":[0.9980712,0.00010103823,0.000043826527,0.0013634217,0.000013819092,0.00003093103,0.000029826517,0.000023831448,0.00032211025],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983437,0.00042749266,0.00029939058,0.0003347644,0.00023434008,0.00036032475],"domain_scores_gemma":[0.9992569,0.00020500143,0.00014884493,0.00028671377,0.000008141473,0.00009437943],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030783901,0.00016403048,0.00017665228,0.00018700739,0.00021790282,0.00005473215,0.00018626357,0.00007096049,0.00009083209],"category_scores_gemma":[0.0001105303,0.00017912648,0.00003843195,0.0003165216,0.00008098898,0.00040453512,0.00008709753,0.0003471362,0.00004966015],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009948497,0.0005709626,0.019807624,0.00008948259,5.471767e-7,0.0000012382142,0.0039570658,0.000009367695,0.9279029,0.00044970476,0.0003117805,0.046799872],"study_design_scores_gemma":[0.003574995,0.00054605055,0.9134864,0.000053611417,0.000002301088,0.000006858491,0.0017740356,0.00028105537,0.07582235,0.00025160203,0.0038072069,0.00039349028],"about_ca_topic_score_codex":0.0009998579,"about_ca_topic_score_gemma":0.00034898988,"teacher_disagreement_score":0.89367884,"about_ca_system_score_codex":0.000111585905,"about_ca_system_score_gemma":0.00010960596,"threshold_uncertainty_score":0.7304566},"labels":[],"label_agreement":null},{"id":"W2997666295","doi":"10.1016/j.jpsychires.2019.12.018","title":"Preliminary study of structural magnetic resonance imaging phenotypes related to genetic variation in Interleukin-1β rs16944 in adolescents with Bipolar Disorder","year":2019,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heart and Stroke Foundation; Centre for Addiction and Mental Health; Sunnybrook Health Science Centre; Health Sciences Centre; University of Toronto","funders":"Canadian Institutes of Health Research; Ontario Mental Health Foundation","keywords":"Biology; Neuroimaging; Anterior cingulate cortex; Single-nucleotide polymorphism; Temporal cortex; Imaging genetics; Dorsolateral prefrontal cortex; Psychology; Genetics; Neuroscience; Prefrontal cortex; Genotype; Gene; Cognition","score_opus":0.014923094698631937,"score_gpt":0.3091266331222129,"score_spread":0.29420353842358093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2997666295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99387765,0.004641398,0.0000131524785,0.00030935407,0.00024790742,0.00084086496,0.0000010243706,0.0000049521277,0.000063686864],"genre_scores_gemma":[0.99949926,0.000057712215,0.0002942455,0.000035650864,0.000027593438,0.0000058333076,7.940842e-8,0.000023311179,0.00005633579],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9967381,0.00071619765,0.00073158,0.0003541757,0.0010467607,0.00041322308],"domain_scores_gemma":[0.9990988,0.00013002277,0.00022954679,0.000290914,0.0001592416,0.00009151263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008152412,0.00014138607,0.00027347184,0.001593325,0.000052203228,0.000045760396,0.0006101501,0.000047801783,0.000044475335],"category_scores_gemma":[0.0002858264,0.00011093819,0.000042055417,0.0027470018,0.00006055509,0.00020596478,0.000115720526,0.00075651106,0.000014958306],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017349814,0.0006494214,0.97477394,0.00006681662,0.0000022130632,0.000052932774,0.0038279882,0.0010370751,0.0056891763,0.0000317811,0.000024077975,0.0121095935],"study_design_scores_gemma":[0.003980103,0.0036521505,0.9884319,0.00026586023,0.000004386089,0.000034518805,0.0014346589,0.0012964159,0.00011856863,0.0006317466,0.000031597017,0.00011809689],"about_ca_topic_score_codex":0.0002674797,"about_ca_topic_score_gemma":0.0001927936,"teacher_disagreement_score":0.0136579545,"about_ca_system_score_codex":0.000101877224,"about_ca_system_score_gemma":0.00016024188,"threshold_uncertainty_score":0.45239282},"labels":[],"label_agreement":null},{"id":"W2999646501","doi":"10.1017/s2045796019000854","title":"Incidence and temporal trends of co-occurring personality disorder diagnoses in immune-mediated inflammatory diseases","year":2020,"lang":"en","type":"article","venue":"Epidemiology and Psychiatric Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Dalhousie University; University of Calgary; University of Manitoba","funders":"Canadian Institutes of Health Research; Max Rady College of Medicine, University of Manitoba; Crohn's and Colitis Canada","keywords":"Medicine; Incidence (geometry); Demography; Cohort; Population; Rate ratio; Inflammatory bowel disease; Cohort study; Epidemiology; Internal medicine; Confidence interval; Disease; Environmental health","score_opus":0.05155200886584297,"score_gpt":0.3366442854290544,"score_spread":0.2850922765632114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999646501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98542607,0.008826765,0.000028495382,0.004994705,0.00012660275,0.00009782716,0.00003517462,0.00003536378,0.00042898188],"genre_scores_gemma":[0.99622047,0.0010120993,0.00015888704,0.0025410482,0.000044761302,0.000010942479,0.0000023222149,0.0000041409367,0.0000053133],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99777836,0.00065492233,0.0004991891,0.00059203245,0.00014088878,0.0003345836],"domain_scores_gemma":[0.9959134,0.003570047,0.0002449793,0.00010004132,0.0000087749695,0.00016278219],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00095651497,0.00015856464,0.00039509384,0.00021178258,0.00025965468,0.000012805403,0.00028991455,0.000083153616,0.0000682935],"category_scores_gemma":[0.005709261,0.00012529976,0.000057138055,0.0009588459,0.0018060415,0.0002528177,0.000085767766,0.0001749016,0.0000032314815],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000420245,0.0000423878,0.99456894,0.00004479688,0.0000019153574,0.0000028971965,0.0005322527,0.000023421326,0.00024716058,0.0019112894,0.00020668624,0.0023761995],"study_design_scores_gemma":[0.0004649635,0.00018540325,0.9943381,0.000014676175,0.0000049906957,0.00000479783,0.00045608886,0.0012824979,0.00006882153,0.0023961856,0.00062969653,0.00015376897],"about_ca_topic_score_codex":0.00020360388,"about_ca_topic_score_gemma":0.00006416317,"teacher_disagreement_score":0.0107944,"about_ca_system_score_codex":0.000004627607,"about_ca_system_score_gemma":0.00007106018,"threshold_uncertainty_score":0.68349314},"labels":[],"label_agreement":null},{"id":"W2999966539","doi":"10.1038/s41537-019-0090-z","title":"The neurobiology of treatment-resistant schizophrenia: paths to antipsychotic resistance and a roadmap for future research","year":2020,"lang":"en","type":"review","venue":"Schizophrenia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":356,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Medical Research Council; H. Lundbeck A/S","keywords":"Schizophrenia (object-oriented programming); Antipsychotic; Clozapine; Clinical trial; Psychosis; Psychology; Medicine; Neuroscience; Psychiatry; Internal medicine","score_opus":0.08493638674928759,"score_gpt":0.37182926576614783,"score_spread":0.2868928790168602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999966539","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00086348725,0.9920801,0.000010339271,0.001373676,0.00083707785,0.0037128732,0.0007687568,0.000087620865,0.00026605022],"genre_scores_gemma":[0.00057325454,0.99622154,0.00070113066,0.0001141537,0.00061638776,0.00066977163,0.00002216025,0.00012711193,0.0009545159],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99489045,0.0013011859,0.000905786,0.0015726077,0.0003873176,0.00094262883],"domain_scores_gemma":[0.99436504,0.0036971727,0.00039555735,0.001089415,0.00011584819,0.0003369917],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005367963,0.00070774945,0.0017730005,0.00035883617,0.0008306271,0.000190023,0.0012614154,0.000377356,0.000011647785],"category_scores_gemma":[0.0011287262,0.00044111887,0.00056293095,0.0015581114,0.00065453094,0.00007194399,0.00026187554,0.00067943736,0.000069055226],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047588763,0.00009892089,3.4567663e-7,0.0040459307,0.00008563978,0.000024700668,0.00018304329,1.7729195e-7,0.0011443564,0.018340524,0.0050572893,0.9662602],"study_design_scores_gemma":[0.001468242,0.0010209574,0.000015693868,0.0014684655,0.00010463965,0.000013892492,0.00006439116,0.0000016200036,0.00023913784,0.001635389,0.99357057,0.0003969863],"about_ca_topic_score_codex":0.000006615104,"about_ca_topic_score_gemma":0.00033308548,"teacher_disagreement_score":0.9885133,"about_ca_system_score_codex":0.00012273014,"about_ca_system_score_gemma":0.00092220015,"threshold_uncertainty_score":0.9998041},"labels":[],"label_agreement":null},{"id":"W3002148242","doi":"10.1038/s41598-020-57967-y","title":"Variation in chemokines plasma concentrations in primary care depressed patients associated with Internet-based cognitive-behavioral therapy","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Instituto de Salud Carlos III; Consejería de Salud y Bienestar Social, Junta de Andalucía; Junta de Andalucía; Ministerio de Economía y Competitividad; Plan Nacional sobre Drogas; European Commission; Ministerio de Ciencia, Innovación y Universidades; Ministerio de Educación, Cultura y Deporte; European Regional Development Fund; Universidad de Málaga","keywords":"Primary care; Variation (astronomy); Cognitive behavioral therapy; Medicine; The Internet; Chemokine; Cognition; Clinical psychology; Psychology; Internal medicine; Psychiatry; World Wide Web; Inflammation; Family medicine; Computer science","score_opus":0.03123608600934407,"score_gpt":0.25394600675251777,"score_spread":0.2227099207431737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3002148242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99795556,0.000014925807,0.00006193654,0.000070641436,0.0005781319,0.0006989192,0.000015528432,0.00007034055,0.0005340057],"genre_scores_gemma":[0.9992343,9.0637116e-7,0.000021512462,0.00035295132,0.000007930499,0.000051870436,0.000269583,0.000015298667,0.000045648518],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9980269,0.000119855045,0.00036937522,0.0007508993,0.00047127358,0.00026171663],"domain_scores_gemma":[0.9993013,0.000087006796,0.00024703165,0.00016908016,0.00011753438,0.000078038574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014266247,0.00014668496,0.00016851173,0.00012915875,0.00008637941,0.0001838202,0.00012193522,0.00006519529,0.0000461079],"category_scores_gemma":[0.00042999367,0.00013060735,0.000037446258,0.0010039534,0.00018188776,0.00026218704,0.000026025593,0.00014012745,0.0000043962755],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002514784,0.0011757207,0.82996327,0.000026632908,0.0000039860693,0.00032695755,0.008138877,0.0003690724,0.15630244,0.000008216594,0.00015737042,0.003275982],"study_design_scores_gemma":[0.0033414976,0.00017084392,0.72169846,0.00012536073,0.0000052134183,0.0000016946253,0.0002122568,0.0012729812,0.2727633,0.00003346919,0.00013219244,0.00024271185],"about_ca_topic_score_codex":0.000040110983,"about_ca_topic_score_gemma":0.00022322996,"teacher_disagreement_score":0.11646089,"about_ca_system_score_codex":0.000114608185,"about_ca_system_score_gemma":0.00024452328,"threshold_uncertainty_score":0.5326013},"labels":[],"label_agreement":null},{"id":"W3002221608","doi":"10.1016/j.bbi.2020.01.011","title":"The relationship between plasma serotonin and kynurenine pathway metabolite levels and the treatment response to escitalopram and desvenlafaxine","year":2020,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"Janssen Research and Development","keywords":"Escitalopram; Metabolite; Kynurenine; Pharmacology; Serotonin; Kynurenine pathway; Citalopram; Plasma concentration; Medicine; Chemistry; Internal medicine; Tryptophan; Antidepressant; Hippocampus; Biochemistry; Receptor","score_opus":0.09295589247186287,"score_gpt":0.30613097496732644,"score_spread":0.21317508249546357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3002221608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98370606,0.0007183114,0.000014942027,0.014389502,0.000030338448,0.000926362,0.00013353657,0.000042352793,0.000038616443],"genre_scores_gemma":[0.9985514,0.000109929475,0.000084676765,0.00075258466,0.000024340516,0.0001161589,0.0000044370126,0.000017283142,0.00033914455],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981071,0.0009396552,0.00022413916,0.00033416986,0.00014933347,0.00024559983],"domain_scores_gemma":[0.995164,0.0042748586,0.00006377153,0.00026517865,0.00001772942,0.00021445606],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006908911,0.0002142191,0.0002414542,0.000047137386,0.0010842903,0.0002446219,0.00016054485,0.00006887358,0.0000056225736],"category_scores_gemma":[0.0022843839,0.0001242148,0.000038402803,0.0002536614,0.00067128893,0.00014556592,0.00016728014,0.00024056302,0.0000029434452],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006606167,0.00031239123,0.39966676,0.00004856815,0.000052885793,0.00003712192,0.041417096,0.000001817841,0.34916854,0.010665629,0.00022592452,0.1917971],"study_design_scores_gemma":[0.0030072918,0.00045203566,0.9732099,0.000009202866,0.000042399053,0.000021532585,0.0007114862,0.000022800517,0.01615838,0.0003263364,0.0058718305,0.00016676998],"about_ca_topic_score_codex":0.00005735904,"about_ca_topic_score_gemma":0.000029916375,"teacher_disagreement_score":0.5735432,"about_ca_system_score_codex":0.000013213674,"about_ca_system_score_gemma":0.000032459495,"threshold_uncertainty_score":0.83395946},"labels":[],"label_agreement":null},{"id":"W3003128096","doi":"10.1073/pnas.1914655117","title":"Molecular adaptations of the blood–brain barrier promote stress resilience vs. depression","year":2020,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":350,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Douglas College; Université Laval","funders":"National Institute of Mental Health; National Institutes of Health; National Institute on Drug Abuse; Brain and Behavior Research Foundation; Canada First Research Excellence Fund; Fonds de Recherche du Québec - Santé; Trinity College Dublin; McGill University; Université Laval","keywords":"Blood–brain barrier; Inflammation; Antidepressant; Depression (economics); Chronic stress; Epigenetics; Vulnerability (computing); Neuroscience; Medicine; Psychology; Biology; Immunology; Gene; Central nervous system; Hippocampus","score_opus":0.03506458583979712,"score_gpt":0.28638872604196897,"score_spread":0.25132414020217186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003128096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98107386,0.00007557271,0.000004490218,0.015300551,0.000015478234,0.00027341637,0.00003725651,0.000012755605,0.0032066104],"genre_scores_gemma":[0.9976183,0.0000137877305,0.00037587166,0.0018937413,0.000019011064,0.000008016379,3.267558e-8,0.0000043648865,0.00006688287],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997733,0.000023282531,0.00030087988,0.00032981826,0.0014616769,0.00015136124],"domain_scores_gemma":[0.9991578,0.0001905861,0.0004470116,0.000016541293,0.00013701041,0.000051064093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003959402,0.000094677096,0.0001230368,0.00006781493,0.00025665128,0.00002241342,0.0016152755,0.000058225116,0.000014812954],"category_scores_gemma":[0.004948267,0.00005492981,0.0000963645,0.0013513449,0.0014100617,0.00036024294,0.00028542677,0.00017796207,6.9825177e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012112691,0.00003870149,0.002123346,0.000039031096,0.0000025967129,9.239453e-9,0.0004685419,0.00063209474,0.9720457,0.024197787,0.00022983029,0.00021021217],"study_design_scores_gemma":[0.00016470841,0.000039238028,0.02365388,0.00009144942,0.0000065371473,0.0000020764637,0.00016795992,0.0025217244,0.96328443,0.009887702,0.00011881398,0.00006150616],"about_ca_topic_score_codex":0.000002959065,"about_ca_topic_score_gemma":6.82427e-8,"teacher_disagreement_score":0.021530533,"about_ca_system_score_codex":0.000006715599,"about_ca_system_score_gemma":0.00006195092,"threshold_uncertainty_score":0.59238946},"labels":[],"label_agreement":null},{"id":"W3004840704","doi":"10.1007/s12035-020-01882-w","title":"Increased Levels of Plasma Tumor Necrosis Factor-α Mediate Schizophrenia Symptom Dimensions and Neurocognitive Impairments and Are Inversely Associated with Natural IgM Directed to Malondialdehyde and Paraoxonase 1 Activity","year":2020,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Chulalongkorn University","keywords":"Malondialdehyde; PON1; Psychology; Paraoxonase; Schizophrenia (object-oriented programming); Internal medicine; Medicine; Psychiatry; Immunology; Oxidative stress; Genotype; Chemistry","score_opus":0.018356236531283956,"score_gpt":0.2255738611334448,"score_spread":0.20721762460216084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004840704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99790186,0.00002130367,0.000007919178,0.00066580693,0.00005797047,0.00060274545,0.0006153385,0.00011692781,0.0000101357655],"genre_scores_gemma":[0.9953121,0.000013242141,0.000053265834,0.0045433636,0.0000065745485,0.000020665448,0.00001169997,0.00003553759,0.0000035610942],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99783754,0.0006056838,0.0002020486,0.000816904,0.00015001463,0.00038783514],"domain_scores_gemma":[0.99866706,0.0005788797,0.0002049545,0.00014075167,0.000053778662,0.00035460043],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000045189983,0.00032965,0.00046527028,0.00013027084,0.00012576526,0.000036133053,0.00013198426,0.000093929666,0.000007992943],"category_scores_gemma":[0.0017684408,0.00028571836,0.000043893433,0.00042827806,0.00041971946,0.00011162677,0.00027240443,0.00029172827,0.000002663339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008690754,0.00008321947,0.0076339957,0.000020971776,0.000034123437,0.0002818774,0.00025970946,0.000004211948,0.9905253,0.000009725209,0.000021858265,0.00025594846],"study_design_scores_gemma":[0.0029260411,0.0008189665,0.47549298,0.00003465257,0.000036875055,0.00004956577,0.000026440308,0.0005316034,0.5197706,0.000023274264,0.0000094003435,0.00027956167],"about_ca_topic_score_codex":0.00003616063,"about_ca_topic_score_gemma":0.000042757012,"teacher_disagreement_score":0.47075465,"about_ca_system_score_codex":0.000011870264,"about_ca_system_score_gemma":0.000047690257,"threshold_uncertainty_score":0.99995947},"labels":[],"label_agreement":null},{"id":"W3007631121","doi":"10.1016/bs.acc.2019.08.005","title":"Tryptophan in health and disease","year":2020,"lang":"en","type":"review","venue":"Advances in clinical chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":299,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Immune system; Kynurenine; Biology; Melatonin; Tryptophan; Serotonin; Homeostasis; Immunology; Amino acid; Neuroscience; Endocrinology; Biochemistry","score_opus":0.09511259804195697,"score_gpt":0.4515160584000445,"score_spread":0.3564034603580875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3007631121","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006337078,0.99778384,0.0000032720072,0.00038299055,0.00015943247,0.00034393396,0.00004614024,0.00004538568,0.0011716419],"genre_scores_gemma":[0.00017029284,0.9979118,0.000065924425,0.0014106418,0.00017817222,0.000057850142,0.000017310085,0.000035595145,0.00015243194],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99656713,0.00028434352,0.00145052,0.0011185969,0.00019850703,0.000380873],"domain_scores_gemma":[0.9965896,0.0018942395,0.0004268987,0.00035697196,0.000004276907,0.0007280119],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002828821,0.0003522667,0.0015314226,0.00003781992,0.000032654396,0.000026520318,0.00047959367,0.00023054205,0.000039843042],"category_scores_gemma":[0.008661491,0.00031414191,0.00026062346,0.00047782122,0.00033667832,0.00012873343,0.00019687467,0.0011268625,0.000023075416],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024656085,0.00013019696,0.00011303449,0.020598713,0.0000014884887,0.00013807882,0.000010723626,5.533874e-7,8.2512116e-7,0.00007596655,0.00007500717,0.97883075],"study_design_scores_gemma":[0.0004535624,0.00002674127,0.00000851281,0.0061224946,0.0000057345283,0.0000060926336,0.000013712156,0.000009134696,0.000006477257,0.0014744465,0.9915838,0.0002892655],"about_ca_topic_score_codex":0.0000012423556,"about_ca_topic_score_gemma":0.0000028087063,"teacher_disagreement_score":0.99150884,"about_ca_system_score_codex":0.00006771865,"about_ca_system_score_gemma":0.0006925322,"threshold_uncertainty_score":0.99993104},"labels":[],"label_agreement":null},{"id":"W3009697500","doi":"10.1016/j.pnpbp.2020.109909","title":"Neural and molecular correlates of psychological pain during major depression, and its link with suicidal ideas","year":2020,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Default mode network; Psychology; Serotonergic; Functional magnetic resonance imaging; Chronic pain; Depression (economics); Clinical psychology; Psychiatry; Internal medicine; Neuroscience; Medicine; Serotonin","score_opus":0.021057672330992434,"score_gpt":0.3021494055239743,"score_spread":0.28109173319298186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3009697500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830395,0.008689376,0.000011784842,0.00724007,0.00026706714,0.00057086523,0.000011876959,0.000099564066,0.00006992266],"genre_scores_gemma":[0.990121,0.0007344368,0.00023826242,0.008742466,0.000082193685,0.000058356778,0.0000017485304,0.000019330788,0.0000021990752],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99728596,0.00062023255,0.00041157557,0.0010854937,0.00014060481,0.0004561063],"domain_scores_gemma":[0.9990054,0.00040665182,0.00017163984,0.00011556815,0.000021609361,0.00027913577],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019703168,0.00033700897,0.00041765915,0.00009352135,0.00014312821,0.000028859047,0.0002667621,0.00029566616,0.000057929356],"category_scores_gemma":[0.00026258384,0.00022698531,0.00005004163,0.00037287685,0.00091823045,0.00009821588,0.0001869563,0.0006826212,0.000002238532],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038519555,0.00029700942,0.9514003,0.00012326906,0.000012377531,0.00018605849,0.000075104945,0.0000058662545,0.03912179,0.0005739322,0.00005457489,0.0042977887],"study_design_scores_gemma":[0.0062682345,0.0018908912,0.9860143,0.000031922507,0.000020491332,0.00021293994,0.00004772786,0.0010756151,0.0027248198,0.0012947415,0.000052939187,0.00036534853],"about_ca_topic_score_codex":4.938125e-7,"about_ca_topic_score_gemma":9.962502e-7,"teacher_disagreement_score":0.03639697,"about_ca_system_score_codex":0.0000027257981,"about_ca_system_score_gemma":0.000010410276,"threshold_uncertainty_score":0.92561924},"labels":[],"label_agreement":null},{"id":"W3010550883","doi":"10.17269/s41997-020-00297-3","title":"Association between C-reactive protein and mood disorder in a representative sample of the Canadian population: analysis of CHMS data 2013–2014","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Public Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Association (psychology); Sample (material); Mood; Psychology; Population; Clinical psychology; Medicine; Chemistry; Environmental health; Chromatography; Psychotherapist","score_opus":0.10301818703292927,"score_gpt":0.3282411748033992,"score_spread":0.22522298777046995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010550883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9109035,0.000100051424,0.00013780265,0.08723341,0.00004332142,0.00030129473,0.001188456,0.0000016323629,0.00009051544],"genre_scores_gemma":[0.99896127,0.00001158082,0.00008834592,0.00084494404,0.000034365454,0.0000015555995,0.000037466958,0.000007076802,0.000013377009],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979915,0.0006033495,0.0005371017,0.00020914442,0.00031068415,0.00034820492],"domain_scores_gemma":[0.9975439,0.00030642806,0.00083523185,0.00024647545,0.00012555913,0.00094243686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011548374,0.00008341669,0.00036466375,0.00058052945,0.00014306682,0.0000485391,0.00047771487,0.00006171503,0.000066569],"category_scores_gemma":[0.0063766134,0.00006967862,0.000060739923,0.0017629497,0.00009240105,0.00037628514,0.00003287242,0.0002666652,3.7837555e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002799986,0.000010442199,0.9927939,0.000017055661,0.00010169113,0.000001370796,0.0034437866,0.00005601552,0.00003699311,0.00031126937,0.0011542081,0.0020704416],"study_design_scores_gemma":[0.00034721484,0.000063513864,0.99520105,0.000017779075,0.00003207391,7.5474696e-7,0.0011036355,0.0005170614,0.000053746553,0.00022702951,0.0023742623,0.00006188355],"about_ca_topic_score_codex":0.9056387,"about_ca_topic_score_gemma":0.9909705,"teacher_disagreement_score":0.08805777,"about_ca_system_score_codex":0.00049652625,"about_ca_system_score_gemma":0.004495829,"threshold_uncertainty_score":0.7975407},"labels":[],"label_agreement":null},{"id":"W3011389959","doi":"10.1038/s41398-020-0776-z","title":"Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function","year":2020,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Turun Yliopisto; Academy of Finland","keywords":"Medicine; Internal medicine; Immune system; Translocator protein; Psychosis; Immune dysregulation; Chemokine; Antipsychotic; Immunology; Schizophrenia (object-oriented programming); Inflammation; Psychiatry; Neuroinflammation","score_opus":0.015773074560016555,"score_gpt":0.23544731444459596,"score_spread":0.2196742398845794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011389959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9647105,0.0002016689,0.00080302416,0.03246915,0.0002300547,0.0004366509,0.00029300558,0.0000750296,0.00078093086],"genre_scores_gemma":[0.9957458,0.000017427003,0.0003801084,0.00350482,0.000083627354,0.00003241972,0.000021760232,0.00003301288,0.00018102911],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982677,0.00010382642,0.0004226593,0.00052593526,0.00034647435,0.00033338973],"domain_scores_gemma":[0.99952203,0.0001224471,0.00011714654,0.00011699704,0.000023309412,0.00009807846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012468049,0.00023236244,0.00023127567,0.00012814761,0.00013102566,0.000053358854,0.00014612827,0.00010574489,0.00037222228],"category_scores_gemma":[0.00003105994,0.00023414505,0.00005767308,0.0008474988,0.00007466458,0.0003270873,0.000010792852,0.00033152231,0.000013478646],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022251818,0.0010617936,0.8767435,0.00020901405,0.000046163383,0.000007989685,0.004074708,0.012895099,0.09779028,0.0017753236,0.0021581515,0.0010127968],"study_design_scores_gemma":[0.007430053,0.00022983344,0.9789614,0.00005242459,0.000011077967,0.000002853052,0.00009997521,0.005238676,0.0041572056,0.0023101433,0.001109842,0.00039650552],"about_ca_topic_score_codex":0.00008436274,"about_ca_topic_score_gemma":0.0032512487,"teacher_disagreement_score":0.10221791,"about_ca_system_score_codex":0.000034152636,"about_ca_system_score_gemma":0.000071488765,"threshold_uncertainty_score":0.9548158},"labels":[],"label_agreement":null},{"id":"W3011903846","doi":"10.1080/09540261.2019.1708708","title":"Melancholia: does this ancient concept have contemporary utility?","year":2020,"lang":"en","type":"review","venue":"International Review of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Melancholia; Melancholic depression; Depression (economics); Psychology; Clinical psychology; Psychiatry; Antidepressant; Psychotherapist; Cognition; Anxiety","score_opus":0.055773420425419495,"score_gpt":0.35865022924606405,"score_spread":0.30287680882064455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011903846","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[4.9609577e-7,0.94355625,0.000032265718,0.0034478009,0.005175305,0.0011107507,0.0008251493,0.00006795596,0.045784026],"genre_scores_gemma":[0.000054294414,0.98965293,0.00022446392,0.008478359,0.0005532613,0.000098085155,0.000113911265,0.00005240166,0.00077226874],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960073,0.00038120255,0.0015371523,0.0009185918,0.0009027642,0.00025293755],"domain_scores_gemma":[0.99750173,0.00031987665,0.001315741,0.00058027945,0.000115356735,0.00016700417],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000291987,0.0005273317,0.0019053859,0.00015789454,0.000055301294,0.00004277558,0.0016231666,0.00019301519,0.0026419444],"category_scores_gemma":[0.0012116896,0.00035347743,0.0013019706,0.00036394797,0.00026528697,0.00017723588,0.0002499121,0.0005954085,0.0004024298],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009614951,0.00021229696,0.000022190467,0.07840683,0.00012289839,0.000023855873,0.000038574737,1.5871159e-8,0.0000024177184,0.0120274145,0.21552746,0.69360644],"study_design_scores_gemma":[0.00019992246,0.000035400793,0.000004983493,0.08493398,0.00009218741,0.000034168894,0.000013009508,0.0000030761853,0.000015349859,0.00049619895,0.9138673,0.0003044379],"about_ca_topic_score_codex":0.000012630048,"about_ca_topic_score_gemma":0.0000044052886,"teacher_disagreement_score":0.6983398,"about_ca_system_score_codex":0.000069681286,"about_ca_system_score_gemma":0.000965923,"threshold_uncertainty_score":0.9998917},"labels":[],"label_agreement":null},{"id":"W3012254838","doi":"10.3138/jmvfh.2019-0036","title":"Biomarkers for military mental health: Insights, challenges, and future prospects","year":2020,"lang":"en","type":"article","venue":"Journal of Military Veteran and Family Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Government of Canada; Canadian Armed Forces; Department of National Defence; Defence Research and Development Canada","funders":"","keywords":"Disease; Mental health; Modalities; Medicine; Personalized medicine; Standardization; Psychiatry; Bioinformatics; Biology; Pathology; Computer science","score_opus":0.05560571090546554,"score_gpt":0.28654300885702705,"score_spread":0.2309372979515615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012254838","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.38284305,0.520299,0.000028263485,0.09550822,0.0005056269,0.000639238,0.000076767334,0.000024279678,0.00007554239],"genre_scores_gemma":[0.48284847,0.4653649,0.0020103597,0.049041722,0.0006848588,0.0000056682284,0.000006694695,0.000030949734,0.000006385749],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99804085,0.00024225647,0.0006385326,0.00040388742,0.0002830187,0.00039147882],"domain_scores_gemma":[0.99881333,0.00013458358,0.0001814781,0.000119719996,0.000033522938,0.00071735046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036505298,0.0002269841,0.00050788245,0.00012624421,0.00030319596,0.0000074899303,0.00016909055,0.00006952313,0.0000036355266],"category_scores_gemma":[0.00007020682,0.00018229219,0.00012081752,0.00012841291,0.00015285896,0.00027851883,0.00004342304,0.00027494447,0.0000010224761],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0053915116,0.0006287741,0.00017063224,0.004032425,0.00014072003,0.000108091604,0.090159506,0.0000034997518,0.0267429,0.0016406769,0.09295557,0.7780257],"study_design_scores_gemma":[0.01916098,0.02973063,0.09879266,0.00077271083,0.000027124794,0.00086036517,0.04422386,0.0017592456,0.0005777745,0.0030270603,0.79994935,0.0011182657],"about_ca_topic_score_codex":0.000038818434,"about_ca_topic_score_gemma":0.000036948375,"teacher_disagreement_score":0.77690744,"about_ca_system_score_codex":0.000060722214,"about_ca_system_score_gemma":0.00023018775,"threshold_uncertainty_score":0.743366},"labels":[],"label_agreement":null},{"id":"W3012995061","doi":"10.1186/s12974-020-01759-8","title":"Sustained exposure to systemic endotoxin triggers chemokine induction in the brain followed by a rapid influx of leukocytes","year":2020,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Medical Research Council; Dr Mortimer and Theresa Sackler Foundation; University of Glasgow; Wellcome Trust","keywords":"CXCL2; Chemokine; CCL7; CXCL1; Immunology; CXCL14; CCL5; CXCL10; Microglia; CCL2; CCL13; Chemotaxis; Medicine; Inflammation; CXCL9; Leukocyte Trafficking; CCL3; Biology; Immune system; Chemokine receptor; T cell; Internal medicine; Receptor","score_opus":0.023012047301304274,"score_gpt":0.2457411277294337,"score_spread":0.22272908042812944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012995061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98407066,0.000063342544,0.00017596138,0.01489872,0.00012534003,0.00047429267,0.0000035567784,0.000016129034,0.00017200541],"genre_scores_gemma":[0.9986922,0.000033622517,0.00003335345,0.0010719099,0.00012448801,0.000006558398,0.0000013266712,0.0000145468375,0.000021953461],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979018,0.00043836233,0.0007812302,0.00017572653,0.00052498624,0.00017788763],"domain_scores_gemma":[0.99860895,0.00043456332,0.0006432182,0.00014291101,0.00008513279,0.000085205305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005375619,0.00013945226,0.00027118498,0.00023012012,0.00004739601,0.000051785722,0.00037185673,0.00005900827,0.00001674061],"category_scores_gemma":[0.003610071,0.00010350275,0.00012178756,0.0008637529,0.0000371817,0.0004074768,0.000034054156,0.0002878513,0.0000048894653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037788873,0.000042014908,0.0000766779,0.00006719724,0.000003820878,0.00003149692,0.002878588,0.00067544164,0.98935884,0.00008811049,0.003908409,0.0024915393],"study_design_scores_gemma":[0.0023819862,0.0009735368,0.0014622045,0.00006787019,0.000009686368,0.00013950357,0.0018467115,0.00028143334,0.9915402,0.00006452373,0.0011207346,0.00011163655],"about_ca_topic_score_codex":0.00000257417,"about_ca_topic_score_gemma":0.0000014329152,"teacher_disagreement_score":0.014621588,"about_ca_system_score_codex":0.000049485065,"about_ca_system_score_gemma":0.000088410794,"threshold_uncertainty_score":0.4321853},"labels":[],"label_agreement":null},{"id":"W3014073663","doi":"10.1016/j.biopsych.2020.03.007","title":"Translocator Protein Distribution Volume Predicts Reduction of Symptoms During Open-Label Trial of Celecoxib in Major Depressive Disorder","year":2020,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Center for Research Resources; National Institute of Mental Health; National Institutes of Health; Janssen Pharmaceuticals; National Institute on Drug Abuse; Brain and Behavior Research Foundation; Canada Research Chairs; Azrieli Foundation; Canada Foundation for Innovation; Canadian Institutes of Health Research; Jazz Pharmaceuticals","keywords":"Translocator protein; Gliosis; Celecoxib; Internal medicine; Medicine; Major depressive disorder; Positron emission tomography; Anterior cingulate cortex; Pathology; Psychiatry; Nuclear medicine; Disease; Cognition","score_opus":0.036661365664568804,"score_gpt":0.2747964623036514,"score_spread":0.2381350966390826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014073663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953958,0.00017944307,0.00025922747,0.0017940162,0.00032483262,0.0017316457,0.0001313635,0.00005056559,0.00013311769],"genre_scores_gemma":[0.9994366,0.00002577207,0.00015591858,0.000077982026,0.00011798729,0.00012469149,0.000026310709,0.0000105689505,0.000024166675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828786,0.00022505182,0.0005232738,0.00052888744,0.00017702136,0.00025790845],"domain_scores_gemma":[0.99943304,0.000029165027,0.00024263606,0.00017732356,0.000022493023,0.000095360345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000098685516,0.0001671027,0.00032639113,0.000038569422,0.00006755779,0.000016349246,0.00048829644,0.00019204247,0.000065274086],"category_scores_gemma":[0.00039261451,0.00013283428,0.000073650575,0.0005066473,0.00023187314,0.0001406695,0.000101046346,0.00020563605,0.000006866755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.030127397,0.0030164095,0.009608106,0.00019637312,0.000014652578,0.0000023275325,0.00017308998,0.00002646925,0.9522972,0.0025333753,0.00020893672,0.0017956536],"study_design_scores_gemma":[0.24353892,0.010138699,0.13667063,0.00034174096,0.000038291997,0.000011309891,0.0005469762,0.0007408129,0.6005324,0.005832531,0.00059784495,0.0010098475],"about_ca_topic_score_codex":0.000024190189,"about_ca_topic_score_gemma":0.0000067091883,"teacher_disagreement_score":0.3517648,"about_ca_system_score_codex":0.000017242719,"about_ca_system_score_gemma":0.000070589034,"threshold_uncertainty_score":0.5416825},"labels":[],"label_agreement":null},{"id":"W3014724450","doi":"10.1016/j.jad.2020.03.145","title":"The Association Between Adverse Childhood Experiences and Inflammation in Patients with Major Depressive Disorder: A Systematic Review","year":2020,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brain and Cognition Discovery Foundation; University Health Network; University of Toronto","funders":"","keywords":"Major depressive disorder; Medicine; Depression (economics); Clinical psychology; PsycINFO; Internal medicine; Psychiatry; Oncology; Psychology; MEDLINE; Mood","score_opus":0.007101309480573363,"score_gpt":0.25222971523250876,"score_spread":0.2451284057519354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014724450","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005800003,0.9898171,0.000020756645,0.0002027723,0.00011382669,0.0039401483,0.000016820293,0.0000141648425,0.00007444192],"genre_scores_gemma":[0.013472709,0.9860935,0.0000054998864,0.000070395436,0.000046490757,0.00025969924,0.0000060028715,0.000038809056,0.0000068933214],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9958622,0.0015521202,0.0011237916,0.00036360757,0.0007961648,0.00030210652],"domain_scores_gemma":[0.99370265,0.0024915983,0.003386216,0.00019632325,0.0001172014,0.00010600942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005993827,0.00043332967,0.0019690243,0.00021526999,0.00023845497,0.000093545146,0.00049223565,0.00016390704,0.000004011416],"category_scores_gemma":[0.0066014337,0.00023825203,0.00034309024,0.0008874833,0.00011897917,0.00045614556,0.000081038765,0.00071032014,0.0000062538297],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006943085,0.00029164818,0.008247394,0.3643969,0.0007962505,0.000015342237,0.0050256136,0.000003906248,3.1706315e-7,0.00006773624,0.000118778415,0.6209667],"study_design_scores_gemma":[0.009134612,0.0024022078,0.022842674,0.903991,0.006686278,0.000033244403,0.0052116206,0.000006180672,0.000012819002,0.00045673543,0.047291458,0.0019311659],"about_ca_topic_score_codex":0.000005844252,"about_ca_topic_score_gemma":0.000065689994,"teacher_disagreement_score":0.6190355,"about_ca_system_score_codex":0.0002528945,"about_ca_system_score_gemma":0.00021947449,"threshold_uncertainty_score":0.9715636},"labels":[],"label_agreement":null},{"id":"W3015582409","doi":"10.1016/j.bbi.2020.04.014","title":"CD4+CD25+ T Cells are Essential for Behavioral Effects of Lactobacillus rhamnosus JB-1 in Male BALB/c mice","year":2020,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Office of Naval Research","keywords":"IL-2 receptor; Adoptive cell transfer; Immune system; Lactobacillus rhamnosus; Anxiolytic; Gut flora; Neuroinflammation; Immunology; Biology; Population; Pharmacology; Medicine; Receptor; T cell; Internal medicine; Inflammation; Lactobacillus; Biochemistry","score_opus":0.029085425089194896,"score_gpt":0.2788293330331929,"score_spread":0.249743907943998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3015582409","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99781334,0.00013457733,0.000049753817,0.00044089163,0.00025788782,0.0009836531,0.0001601486,0.000050512124,0.000109218665],"genre_scores_gemma":[0.9987176,0.00003282592,0.00013482178,0.00077124144,0.000033884255,0.00009199818,0.0000150991145,0.000030023803,0.00017248694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984234,0.0002320203,0.00033490566,0.00042152012,0.00020253529,0.00038563862],"domain_scores_gemma":[0.99882907,0.0005041101,0.00015632325,0.0003383284,0.000037051454,0.00013513505],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012864935,0.00024435503,0.0003725788,0.000096601,0.00014948795,0.00004828024,0.00046089306,0.00014755221,0.00007332793],"category_scores_gemma":[0.0005362884,0.0002509752,0.00013722533,0.00033709087,0.00025745973,0.00019309398,0.00023341402,0.00030422138,0.000008844499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018817073,0.00067897345,0.0066787535,0.0001989522,0.0000020941686,0.00004846922,0.0010847141,0.0000016539713,0.98726344,0.00004104107,0.0009716599,0.0028421055],"study_design_scores_gemma":[0.0032164878,0.0005237668,0.119189925,0.000051021307,0.000039749466,0.000013134963,0.00056267803,0.000040550174,0.87530047,0.000029290666,0.0007101894,0.0003227552],"about_ca_topic_score_codex":0.0002470558,"about_ca_topic_score_gemma":0.000083201885,"teacher_disagreement_score":0.11251117,"about_ca_system_score_codex":0.0000226476,"about_ca_system_score_gemma":0.000042687487,"threshold_uncertainty_score":0.9999943},"labels":[],"label_agreement":null},{"id":"W3015973916","doi":"10.1016/j.jad.2020.03.062","title":"DNA methylation differences in stress-related genes, functional connectivity and gray matter volume in depressed and healthy adolescents","year":2020,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Concordia University; Hotel Dieu Hospital; McGill University","funders":"Canadian Institutes of Health Research; Government of Ontario","keywords":"FKBP5; Psychology; Orbitofrontal cortex; Functional magnetic resonance imaging; DNA methylation; Major depressive disorder; Prefrontal cortex; Methylation; Neuroscience; Amygdala; Internal medicine; Medicine; Genetics; Biology; Gene; Gene expression; Glucocorticoid receptor; Cognition","score_opus":0.017693209364306045,"score_gpt":0.23922302917907123,"score_spread":0.2215298198147652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3015973916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962785,0.0006393668,0.00047921416,0.0021453646,0.00012276533,0.00025599354,0.000008071157,0.000008569158,0.000062141524],"genre_scores_gemma":[0.9989821,0.00028474093,0.000011672509,0.00068085827,0.000019712406,0.000004420162,8.833716e-7,0.000011733656,0.000003931544],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99854904,0.00042881802,0.00030358543,0.00029434054,0.00022597965,0.00019821677],"domain_scores_gemma":[0.9992948,0.0002839134,0.00022823439,0.00004946571,0.000028483886,0.000115081755],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018194906,0.00015471173,0.00028731104,0.00022018937,0.000063690626,0.000040153474,0.00008480944,0.00007954232,0.000036591904],"category_scores_gemma":[0.0004216914,0.00013572915,0.000045852128,0.00039562662,0.00013881242,0.00036226946,0.00004008131,0.00035194436,0.0000029210778],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044681216,0.00019982977,0.96835804,0.00006246939,0.000009071669,0.00000757039,0.0008064358,0.00018237632,0.020985182,0.00002950872,0.000043544653,0.00886918],"study_design_scores_gemma":[0.0029962813,0.00029413123,0.9917026,0.00006936214,0.0000062616386,0.0000074329128,0.0004735465,0.0014002629,0.001905581,0.0009988286,0.000012828037,0.0001328841],"about_ca_topic_score_codex":0.00008218513,"about_ca_topic_score_gemma":0.00045362161,"teacher_disagreement_score":0.023344582,"about_ca_system_score_codex":0.00003881374,"about_ca_system_score_gemma":0.000043787848,"threshold_uncertainty_score":0.5534874},"labels":[],"label_agreement":null},{"id":"W3016273457","doi":"10.1186/s12888-020-02553-9","title":"Minocycline as adjunctive treatment for treatment-resistant depression: study protocol for a double blind, placebo-controlled, randomized trial (MINDEP2)","year":2020,"lang":"en","type":"article","venue":"BMC Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Department of Psychiatry, University of Toronto; South London and Maudsley NHS Foundation Trust; University of Toronto; Physicians' Services Incorporated Foundation; King's College London; National Institute for Health and Care Research","keywords":"Minocycline; Major depressive disorder; Adjunctive treatment; Antidepressant; Clinical Global Impression; Placebo; Treatment-resistant depression; Randomized controlled trial; Medicine; Depression (economics); Clinical trial; Psychiatry; Anxiety; Internal medicine; Mood","score_opus":0.10447055324765935,"score_gpt":0.3835180795899825,"score_spread":0.27904752634232316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016273457","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1219272,0.000055949655,0.0015656616,0.0012183582,0.0011020671,0.8722632,0.00013051965,0.00024212182,0.0014949569],"genre_scores_gemma":[0.08064092,0.000001992031,0.0021127989,0.0005988853,0.001224024,0.913501,0.000018152828,0.00008120583,0.0018209727],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9963096,0.0004711198,0.00096250046,0.0012951553,0.00038187974,0.0005797898],"domain_scores_gemma":[0.9971452,0.0014687603,0.00051929516,0.00049385196,0.00006102005,0.00031190793],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033318627,0.0006378803,0.0015986176,0.00012642276,0.00043077927,0.00014358069,0.0003574507,0.0001694559,0.00014286426],"category_scores_gemma":[0.00077508856,0.00040230135,0.001281706,0.00025246263,0.00010967881,0.0001470212,0.00004260664,0.00007852572,0.00003863285],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9890937,0.006803531,0.00014418543,0.00007181744,0.0002493225,0.0000019669196,0.000717938,0.00003585747,0.00079202943,0.0004167123,0.0010350033,0.00063791487],"study_design_scores_gemma":[0.96958834,0.01569639,0.00000913703,0.000026724234,0.00039423202,0.0000022549295,0.0007105964,0.000987037,0.005587202,0.00081666926,0.0057645054,0.00041692576],"about_ca_topic_score_codex":0.000049831466,"about_ca_topic_score_gemma":0.00035346,"teacher_disagreement_score":0.04128628,"about_ca_system_score_codex":0.00009059647,"about_ca_system_score_gemma":0.0007129571,"threshold_uncertainty_score":0.9998429},"labels":[],"label_agreement":null},{"id":"W3016716658","doi":"10.3389/fpsyt.2020.00276","title":"Functional Neuroimaging in Psychiatry—Aiding in Diagnosis and Guiding Treatment. What the American Psychiatric Association Does Not Know","year":2020,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lions Gate Hospital; University of British Columbia; Southlake Regional Health Center","funders":"","keywords":"Neuroimaging; Psychiatry; Functional neuroimaging; Psychopathology; Psychology; Pathognomonic; Medicine; Disease; Pathology","score_opus":0.03580716517209183,"score_gpt":0.29428454827905,"score_spread":0.25847738310695817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016716658","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0034609465,0.9535465,0.00005269302,0.0109851025,0.030243875,0.0014031894,0.000054979617,0.00009367754,0.00015899287],"genre_scores_gemma":[0.00085296243,0.9939706,0.001559739,0.0021539847,0.00072264543,0.0005120012,0.00001889282,0.000120972414,0.00008823825],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9946945,0.001100648,0.0012394951,0.0015787721,0.00052846456,0.0008581497],"domain_scores_gemma":[0.997569,0.00069598167,0.0010893561,0.0004904871,0.000014776505,0.00014035765],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005109707,0.00083020335,0.0018001561,0.0014030723,0.00028640017,0.00046303458,0.0006501188,0.00022790757,0.000016756949],"category_scores_gemma":[0.0004538464,0.0006027081,0.00048458282,0.003696739,0.0001877785,0.0006626445,0.00013998475,0.0009314947,0.000018629447],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058370184,0.00036239106,0.19212528,0.00101685,0.000049750302,0.00001647707,0.00024356329,0.000013128554,0.0000017426494,0.00030328537,0.019052088,0.7867571],"study_design_scores_gemma":[0.00326618,0.0003233255,0.023637015,0.0074009155,0.00039583992,0.00004280749,0.0035613494,0.0004621474,0.0000072744206,0.004053321,0.9549896,0.0018601945],"about_ca_topic_score_codex":0.000118100135,"about_ca_topic_score_gemma":0.0006755535,"teacher_disagreement_score":0.9359375,"about_ca_system_score_codex":0.00089101715,"about_ca_system_score_gemma":0.0005290896,"threshold_uncertainty_score":0.99964243},"labels":[],"label_agreement":null},{"id":"W3016934891","doi":"10.1096/fasebj.2020.34.s1.05290","title":"Exploring the Role of Immunological Biomarkers in the Association Between Mental Health Status and Executive Function in Early Adulthood","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Brock University","funders":"","keywords":"Anxiety; Mental health; Depression (economics); Psychology; Clinical psychology; Mood; Association (psychology); Life expectancy; Disease; Longitudinal study; Psychiatry; Affect (linguistics); Cognition; Medicine; Internal medicine; Population","score_opus":0.052587970699124666,"score_gpt":0.2547110554808464,"score_spread":0.20212308478172172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016934891","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99243146,0.00034226783,0.000012094812,0.006801199,0.00006492918,0.00019228793,0.000012130859,0.000006365758,0.00013728451],"genre_scores_gemma":[0.99864376,0.00062616996,0.0000052880937,0.00067154394,0.000041270177,0.0000055360047,8.4734774e-7,0.000004053717,0.0000015083498],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99838525,0.0008054972,0.00021752718,0.000106873136,0.00025741148,0.00022743548],"domain_scores_gemma":[0.99931127,0.00039135793,0.00018853352,0.000060964965,0.000009343243,0.000038543694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00075516367,0.00006934527,0.00010580207,0.000043375592,0.00021794002,0.000052874024,0.00019268767,0.000021616816,0.0000040674854],"category_scores_gemma":[0.00030079237,0.00003420611,0.000036240355,0.00033378953,0.00007183555,0.00018525617,0.00004344324,0.00040842884,0.0000020689336],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009232334,0.00015046359,0.5054588,0.000010381853,0.00007915473,0.0000052631794,0.14865607,0.000030528612,0.26914918,0.00093371293,0.00012424753,0.074479],"study_design_scores_gemma":[0.0008663471,0.0003722082,0.9435281,0.000021677333,0.0000051758298,0.000004799148,0.036336467,0.000057893372,0.017791359,0.0007676231,0.00019571513,0.000052609197],"about_ca_topic_score_codex":0.000084184234,"about_ca_topic_score_gemma":0.000014640836,"teacher_disagreement_score":0.43806937,"about_ca_system_score_codex":0.00007923142,"about_ca_system_score_gemma":0.00003790788,"threshold_uncertainty_score":0.17744428},"labels":[],"label_agreement":null},{"id":"W3016963607","doi":"10.1016/j.jad.2020.03.074","title":"Prospective associations between hsCRP and GlycA inflammatory biomarkers and depression: The Brazilian longitudinal study of adult health (ELSA-Brasil)","year":2020,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Ministério da Saúde","keywords":"Internal medicine; Depression (economics); Medicine; Confounding; Prospective cohort study; Body mass index; Proportional hazards model; Incidence (geometry); Poisson regression; Population","score_opus":0.021757232404240927,"score_gpt":0.29389187774354225,"score_spread":0.2721346453393013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016963607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994726,0.00045854563,0.00026855402,0.0033886705,0.00009260659,0.00082308374,0.000028117656,0.000017525017,0.00019687822],"genre_scores_gemma":[0.9993421,0.00013449995,0.000030143745,0.00039055932,0.00007291106,0.000008258981,5.4753576e-7,0.000018609637,0.0000023675289],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9980776,0.0004781654,0.00047369953,0.00032667464,0.00041180625,0.00023208783],"domain_scores_gemma":[0.9979714,0.000765522,0.0008041205,0.00012231882,0.0001397429,0.00019687954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033091017,0.00019368749,0.0004267577,0.00012808297,0.00035250795,0.0000543611,0.00023189417,0.00005655098,0.000005864686],"category_scores_gemma":[0.0020345359,0.00013950338,0.000094736475,0.000517155,0.00030423907,0.00033186068,0.000105823216,0.0003745001,8.1670123e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001405273,0.00023721605,0.9724931,0.000034116238,0.00015479607,0.000005278786,0.010322885,0.000012369131,0.0005545623,0.00010170648,0.00033424966,0.015609165],"study_design_scores_gemma":[0.0027825616,0.0015472755,0.9823275,0.000038721628,0.000038822454,0.0000070081037,0.01132887,0.000034589062,0.0009167144,0.00082353514,0.000022357157,0.00013201738],"about_ca_topic_score_codex":0.00012600524,"about_ca_topic_score_gemma":0.0005158848,"teacher_disagreement_score":0.015477147,"about_ca_system_score_codex":0.00005441634,"about_ca_system_score_gemma":0.0001108885,"threshold_uncertainty_score":0.56887823},"labels":[],"label_agreement":null},{"id":"W3017127389","doi":"10.1080/15622975.2020.1755451","title":"Diminished levels of the chemokine fractalkine in post-mortem prefrontal cortex in schizophrenia but not bipolar disorder","year":2020,"lang":"en","type":"article","venue":"The World Journal of Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Brain and Behavior Research Foundation","keywords":"CX3CR1; Microglia; Chemokine; CX3CL1; Neuroscience; Prefrontal cortex; Synaptic pruning; Biology; Inflammation; Immunology; Chemokine receptor","score_opus":0.032996646272524244,"score_gpt":0.26394632253724465,"score_spread":0.2309496762647204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017127389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97098994,0.0010979486,0.000012887677,0.026768135,0.00055778964,0.00025551615,0.000042944135,0.000012353176,0.0002624972],"genre_scores_gemma":[0.9929812,0.00010110932,0.0001709949,0.006487354,0.00019551974,0.0000023221858,6.310714e-7,0.000013944411,0.00004692304],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99783975,0.00037364176,0.00084613817,0.00028202037,0.00034672767,0.00031170744],"domain_scores_gemma":[0.9987203,0.00031822582,0.00057341455,0.0002514803,0.00003488502,0.000101689904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037167728,0.00022143264,0.00044586568,0.00012361427,0.000079234786,0.00002111524,0.001114773,0.00009873558,0.00026702345],"category_scores_gemma":[0.00067540555,0.00010686842,0.00026077416,0.0009469354,0.0003978669,0.00011819103,0.00020248504,0.00094945094,0.000008318573],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004023752,0.0010099941,0.0905562,0.00003447141,0.000031061252,0.000029242696,0.0004959607,0.00009907219,0.889787,0.0016178519,0.00039694484,0.011918455],"study_design_scores_gemma":[0.0025314973,0.00043906533,0.9800548,0.00007543806,0.000009825671,0.00003842711,0.00030750482,0.000078363504,0.014074585,0.001180586,0.0010445936,0.0001652925],"about_ca_topic_score_codex":0.000016901866,"about_ca_topic_score_gemma":0.0002859576,"teacher_disagreement_score":0.88949865,"about_ca_system_score_codex":0.000023148907,"about_ca_system_score_gemma":0.00012244345,"threshold_uncertainty_score":0.43579677},"labels":[],"label_agreement":null},{"id":"W3017283443","doi":"10.1016/j.neubiorev.2020.04.012","title":"Maternal Immune Activation by Poly I:C as a preclinical Model for Neurodevelopmental Disorders: A focus on Autism and Schizophrenia","year":2020,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":196,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Autism; Schizophrenia (object-oriented programming); Offspring; Autism spectrum disorder; Neurodevelopmental disorder; Psychology; Immune system; Psychiatry; Neuroscience; Pregnancy; Medicine; Immunology; Biology; Genetics","score_opus":0.13265813315456748,"score_gpt":0.3915714200311447,"score_spread":0.2589132868765772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017283443","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011445408,0.99097395,0.00066396286,0.00018772265,0.00067729724,0.005680698,0.00038903896,0.000208457,0.00007431738],"genre_scores_gemma":[0.0038139296,0.9924347,0.0004700579,0.0017154566,0.000050451876,0.0010564075,0.000029548391,0.00013638978,0.00029307196],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9940694,0.00037398346,0.0015784106,0.0024138738,0.0007094337,0.00085488416],"domain_scores_gemma":[0.99778813,0.000051198815,0.0010439995,0.0006482859,0.000015232186,0.0004531457],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003870921,0.0010925309,0.0021146417,0.00024678512,0.0004922893,0.0004459413,0.0013437517,0.00036231964,0.000025771273],"category_scores_gemma":[0.0014044465,0.00086250174,0.00078254985,0.0008390079,0.0005483722,0.00054382114,0.00043325257,0.00092217256,0.000111416506],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006814212,0.00023252724,0.0000025126487,0.00084733823,1.8055138e-7,0.0000059228228,0.000032753167,1.5738252e-7,0.005894483,0.00031780326,0.0005498735,0.9920483],"study_design_scores_gemma":[0.000647646,0.00070984464,0.00006139076,0.0023300464,0.000108689914,0.000052131076,0.0000022898757,0.0005058103,0.00022099912,0.0002822453,0.9942454,0.000833512],"about_ca_topic_score_codex":0.000019336303,"about_ca_topic_score_gemma":0.0000030396814,"teacher_disagreement_score":0.9936955,"about_ca_system_score_codex":0.00011007564,"about_ca_system_score_gemma":0.00042483286,"threshold_uncertainty_score":0.99938256},"labels":[],"label_agreement":null},{"id":"W3017323357","doi":"10.21926/obm.icm.2002022","title":"Effects of a Mindfulness-Based Intervention on Circulating Cytokine Levels in Individuals with Amnestic Mild Cognitive Impairment: A Pilot Study","year":2020,"lang":"en","type":"article","venue":"OBM Integrative and Complementary Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Université Laval","funders":"Alzheimer Society; Université Laval","keywords":"Mindfulness; Inflammation; Cytokine; Medicine; Psychological intervention; Depression (economics); Psychoeducation; Internal medicine; Disease; Tumor necrosis factor alpha; Psychology; Clinical psychology; Psychiatry","score_opus":0.0688425483990713,"score_gpt":0.3260954450671371,"score_spread":0.25725289666806583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017323357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99403,0.000040040355,0.0029443179,0.00095316337,0.00003457389,0.0017668965,0.00007390617,0.000023463426,0.00013366148],"genre_scores_gemma":[0.9970485,7.145033e-7,0.000035033794,0.002662307,0.00003229771,0.00016924321,0.000030945732,0.000015695554,0.00000526436],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99805754,0.0004290784,0.00041890636,0.00047651544,0.0003976574,0.0002202855],"domain_scores_gemma":[0.9984198,0.0011445086,0.00020665208,0.00008477046,0.000043770837,0.000100447214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020284388,0.0002685073,0.00044723137,0.00020504427,0.000079967955,0.00001116736,0.00013946739,0.000014685321,0.00022680458],"category_scores_gemma":[0.00039653416,0.00017800106,0.000030429046,0.000555993,0.00026515414,0.00009208521,0.00005137675,0.0002248551,0.0000022992906],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0190464,0.032326296,0.5315043,0.003666133,0.0008870294,0.0014078557,0.11984332,0.00016677019,0.22463347,0.00528644,0.00087339594,0.060358625],"study_design_scores_gemma":[0.044304308,0.098123714,0.40445867,0.004479729,0.00017301072,0.000008105264,0.04218339,0.001198324,0.40393734,0.0006822451,0.000015980162,0.0004351757],"about_ca_topic_score_codex":0.0003258989,"about_ca_topic_score_gemma":0.00030034216,"teacher_disagreement_score":0.17930387,"about_ca_system_score_codex":0.000031804408,"about_ca_system_score_gemma":0.00002619736,"threshold_uncertainty_score":0.7258673},"labels":[],"label_agreement":null},{"id":"W3018689408","doi":"10.1038/s41380-020-0727-3","title":"Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders","year":2020,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":239,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Depression (economics); Cognition; Psychology; Neuroscience; Information processing; Psychiatry; Clinical psychology","score_opus":0.01582508642755077,"score_gpt":0.2859490043105202,"score_spread":0.27012391788296947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3018689408","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00067578856,0.99477315,0.0013705546,0.0004391683,0.00026337738,0.0010605027,0.00011990057,0.00009532419,0.0012022465],"genre_scores_gemma":[0.0048485957,0.98909473,0.00020687073,0.0053916285,0.00006139752,0.0001928833,0.00010158082,0.00008631444,0.000015981666],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99838275,0.00023039672,0.00042388073,0.0005078042,0.00019755078,0.00025764375],"domain_scores_gemma":[0.99933386,0.00014284339,0.00025963743,0.0001326453,0.000011227326,0.00011979046],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008044366,0.0003585677,0.00052238314,0.00031073944,0.0001236329,0.00013976649,0.00013388865,0.00019843351,0.00001400457],"category_scores_gemma":[0.00044160616,0.00031952775,0.00010119578,0.00070631405,0.0001325727,0.0002871564,0.00009687979,0.00043198676,0.000028528117],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021188165,0.00005633212,0.00015322978,0.004790873,0.000014290069,0.0000045365537,0.00026133945,4.623139e-7,0.00004746512,0.000114441726,0.00021793938,0.9943179],"study_design_scores_gemma":[0.0017128314,0.00009521063,0.0002704869,0.008464108,0.00014128066,0.000069391055,0.00033146495,0.00027234826,0.000023486444,0.00065369887,0.9872189,0.00074676936],"about_ca_topic_score_codex":0.000008434127,"about_ca_topic_score_gemma":0.000043140957,"teacher_disagreement_score":0.99357116,"about_ca_system_score_codex":0.000016128315,"about_ca_system_score_gemma":0.00018009939,"threshold_uncertainty_score":0.9999257},"labels":[],"label_agreement":null},{"id":"W3019161673","doi":"10.3389/fpsyt.2020.00264","title":"Commentary: Neurobiology and Therapeutic Potential of Cyclooxygenase-2 (COX-2) Inhibitors for Inflammation in Neuropsychiatric Disorders","year":2020,"lang":"en","type":"letter","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; BC Mental Health & Substance Use Services; University of British Columbia","funders":"","keywords":"Psychiatry; Cyclooxygenase; Medicine; Neuroscience; Psychology; Psychotherapist; Biology; Enzyme","score_opus":0.008205970332475908,"score_gpt":0.22229881402256685,"score_spread":0.21409284369009093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019161673","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12051408,0.001604987,0.00083551963,0.8525357,0.022149721,0.0019934536,0.0002000639,0.00008083912,0.000085598935],"genre_scores_gemma":[0.15218572,0.0014213515,0.002971727,0.84018594,0.0026117682,0.00019285035,0.00019515546,0.00020264438,0.00003284251],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969193,0.00046128893,0.0008236242,0.0009769044,0.0002380462,0.0005808906],"domain_scores_gemma":[0.9989869,0.00014645197,0.00044167903,0.0003508827,0.000013252284,0.00006081901],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000110579815,0.00048735406,0.00067235087,0.0008647501,0.00008724381,0.000034466964,0.0005330004,0.000520079,0.0000071623276],"category_scores_gemma":[0.000075259995,0.0005090226,0.00021847531,0.000773213,0.00033262093,0.000110147615,0.000098134624,0.0012854034,0.0000019954523],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029526738,0.00011530973,0.013191575,0.00056393555,0.000022295757,0.000013562655,0.00016509576,0.00008860834,0.0013856138,0.00007053441,0.97914606,0.0049421517],"study_design_scores_gemma":[0.01907113,0.0024706095,0.029191002,0.00045180382,0.00025607183,0.000035640078,0.001057531,0.008064203,0.0015766897,0.09230098,0.8421919,0.0033324873],"about_ca_topic_score_codex":0.000037760696,"about_ca_topic_score_gemma":0.00007116502,"teacher_disagreement_score":0.1369542,"about_ca_system_score_codex":0.00004252466,"about_ca_system_score_gemma":0.000097564625,"threshold_uncertainty_score":0.99973613},"labels":[],"label_agreement":null},{"id":"W3019382392","doi":"10.1101/2020.04.24.058610","title":"Molecular Characterization of Depression Trait and State","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Major depressive disorder; Transcriptome; Monoaminergic; Neuroscience; Biology; Bioinformatics; Psychology; Gene; Genetics; Cognition; Gene expression","score_opus":0.01572771334068854,"score_gpt":0.21680944358119575,"score_spread":0.2010817302405072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019382392","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953577,0.00013161276,0.0029461659,0.00022519231,0.00027511342,0.00049432466,0.00035625932,0.00020499171,0.000008667708],"genre_scores_gemma":[0.9987182,0.00022720952,0.00039462952,0.00049089984,0.000048435042,0.000042539603,3.17739e-7,0.00007653244,0.000001239202],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979982,0.0001457426,0.00037150914,0.0008886908,0.0003190337,0.0002768312],"domain_scores_gemma":[0.9987853,0.00004165657,0.00037817872,0.00051847694,0.00008609923,0.00019030127],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011570534,0.00033364695,0.00038381084,0.00014626772,0.00006704608,0.00010236572,0.00036282756,0.00021770067,0.000018600147],"category_scores_gemma":[0.00031712523,0.0003547749,0.00008259536,0.00033553794,0.00014270846,0.00013415168,0.0004088116,0.00037882675,0.000008778992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003129064,0.00005523101,0.00056331285,0.00032348855,0.000012306553,0.000033913464,0.000019268151,0.000010768433,0.9986399,0.00029145717,0.000008010854,0.000011087382],"study_design_scores_gemma":[0.0003226221,0.000026901169,0.093208045,0.00015903625,0.000016640359,7.2174644e-9,5.8734264e-7,0.00042966104,0.90515256,0.000009003588,0.00036219196,0.00031274575],"about_ca_topic_score_codex":0.0000065352483,"about_ca_topic_score_gemma":1.4773417e-7,"teacher_disagreement_score":0.09348731,"about_ca_system_score_codex":0.000027854476,"about_ca_system_score_gemma":0.00015599346,"threshold_uncertainty_score":0.99989045},"labels":[],"label_agreement":null},{"id":"W3019495247","doi":"10.1017/s1092852920001017","title":"186 Results From a 12-Month Open-label Safety Study of Lumateperone (ITI-007) in Patients with Stable Symptoms of Schizophrenia","year":2020,"lang":"en","type":"article","venue":"CNS Spectrums","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Medicine; Adverse effect; Depression (economics); Placebo; Extrapyramidal symptoms; Internal medicine; Positive and Negative Syndrome Scale; Psychiatry; Antipsychotic; Psychosis","score_opus":0.029081720679676713,"score_gpt":0.24399376555137903,"score_spread":0.21491204487170232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019495247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99522996,0.000017321983,0.0000111011395,0.00023717925,0.000065513996,0.0012635723,0.00047745198,0.000046628687,0.002651291],"genre_scores_gemma":[0.9993906,0.000007170482,0.0002027551,0.00023608937,0.000020602036,0.000014963554,0.000029470695,0.000035294877,0.000063057094],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976104,0.0001486737,0.00063759665,0.0007362242,0.00050896633,0.0003581644],"domain_scores_gemma":[0.998822,0.00015322359,0.00031470804,0.00054336386,0.000034815155,0.00013193897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011285369,0.00024034402,0.00052391406,0.00009770995,0.00007871217,0.000048033457,0.0008384922,0.0000593868,0.00011215351],"category_scores_gemma":[0.0002939003,0.00020372165,0.000026249514,0.0006998902,0.00014874412,0.00038373127,0.0003519911,0.00021609353,0.000021985832],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.16111669,0.06013878,0.44824338,0.00031663186,0.0004031888,0.00019747241,0.05018951,0.0016152157,0.254989,0.0057183816,0.0023282992,0.01474345],"study_design_scores_gemma":[0.08841256,0.009354247,0.8409343,0.00022030891,0.000030185158,4.5520608e-7,0.0016080035,0.0006375025,0.057800423,0.00028959278,0.00013433902,0.0005781031],"about_ca_topic_score_codex":0.0015250512,"about_ca_topic_score_gemma":0.0011487966,"teacher_disagreement_score":0.3926909,"about_ca_system_score_codex":0.00005259424,"about_ca_system_score_gemma":0.000086526554,"threshold_uncertainty_score":0.83075273},"labels":[],"label_agreement":null},{"id":"W3020249661","doi":"10.1016/j.bbih.2020.100076","title":"Three insights on psychoneuroimmunology of mood disorders to be taken from the COVID-19 pandemic","year":2020,"lang":"en","type":"review","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Providence Health Care; Kingston Health Sciences Centre; Queen's University","funders":"Queen's University","keywords":"Pandemic; Coronavirus disease 2019 (COVID-19); Mood; Psychoneuroimmunology; Surprise; 2019-20 coronavirus outbreak; Mood disorders; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Psychology; Coronavirus; Outbreak; Psychiatry; Medicine; Virology; Anxiety; Disease; Social psychology; Immunology; Infectious disease (medical specialty); Pathology","score_opus":0.23620598823290806,"score_gpt":0.41743663379120216,"score_spread":0.1812306455582941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020249661","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008109814,0.9400167,0.00016513711,0.04004159,0.0013563081,0.007512154,0.0019927144,0.00047843487,0.00032714548],"genre_scores_gemma":[0.0027601167,0.9535887,0.00006004874,0.042465474,0.00008845065,0.0005202087,0.00028610826,0.00017439542,0.000056501216],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99214125,0.0033915907,0.0015138176,0.0013530767,0.0007037776,0.0008965109],"domain_scores_gemma":[0.99041325,0.005374297,0.0011300935,0.0024232783,0.000031106418,0.00062799366],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006032287,0.0009471996,0.0024189388,0.00036456579,0.0008670626,0.000081410275,0.003256554,0.00052301085,0.00019006869],"category_scores_gemma":[0.003224787,0.00071040395,0.0007354414,0.0016713429,0.0006511271,0.00010750075,0.00059878005,0.0025254353,0.00019335454],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015070853,0.0010993226,0.00014849853,0.0016272882,0.00005178045,0.000012717539,0.0043217405,0.0000018775755,0.00033920727,0.0012993341,0.0101807155,0.98076683],"study_design_scores_gemma":[0.0009215835,0.0009860402,0.0026445594,0.00079911435,0.00010456671,0.000034010165,0.0002709772,7.2910234e-7,0.000005974689,0.00049256993,0.9931441,0.00059580005],"about_ca_topic_score_codex":0.005468028,"about_ca_topic_score_gemma":0.0109997075,"teacher_disagreement_score":0.9829634,"about_ca_system_score_codex":0.0004371994,"about_ca_system_score_gemma":0.0020978316,"threshold_uncertainty_score":0.99977577},"labels":[],"label_agreement":null},{"id":"W3020268904","doi":"10.1016/j.jpsychores.2020.110126","title":"Machine-learning models for depression and anxiety in individuals with immune-mediated inflammatory disease","year":2020,"lang":"en","type":"article","venue":"Journal of Psychosomatic Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"George & Fay Yee Centre for Healthcare Innovation; University of Manitoba","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Canada; Multiple Sclerosis Society of Canada; National Multiple Sclerosis Society; Research Manitoba; University of Manitoba","keywords":"Depression (economics); Anxiety; Immune system; Disease; Psychoneuroimmunology; Psychology; Immunology; Clinical psychology; Medicine; Psychiatry; Internal medicine","score_opus":0.07311105869294111,"score_gpt":0.33940544322510124,"score_spread":0.26629438453216014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020268904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944838,0.0011033823,0.0009099438,0.0027215509,0.000031059535,0.00049871445,0.00000826088,0.000014363792,0.00022890496],"genre_scores_gemma":[0.998141,0.00082909246,0.00069697615,0.00021769693,0.000050427116,0.000022933862,0.0000010231666,0.00002294773,0.000017899834],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99770504,0.0004588751,0.00044833147,0.00023711921,0.00082708895,0.00032352319],"domain_scores_gemma":[0.99836576,0.0008471845,0.00021407488,0.00012456047,0.00009755285,0.0003508897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009959522,0.00011539993,0.00022840357,0.00028484582,0.00014078767,0.00010476469,0.000343834,0.00004983299,0.000021566122],"category_scores_gemma":[0.0020675545,0.00008078849,0.000056949604,0.0005421771,0.000134713,0.00042405826,0.00007414255,0.0006593418,0.000004168682],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0057488764,0.0008586174,0.70521814,0.0019769382,0.000085278305,0.0003369532,0.015417576,0.009360195,0.23357862,0.0013646525,0.0018559127,0.024198214],"study_design_scores_gemma":[0.026800398,0.0027637174,0.3826248,0.0028033701,0.000038820315,0.00012658822,0.004012444,0.5242627,0.015236474,0.03339971,0.006987594,0.00094334397],"about_ca_topic_score_codex":0.0000025880888,"about_ca_topic_score_gemma":0.000001335198,"teacher_disagreement_score":0.51490253,"about_ca_system_score_codex":0.000020727528,"about_ca_system_score_gemma":0.00013025006,"threshold_uncertainty_score":0.3294459},"labels":[],"label_agreement":null},{"id":"W3021255233","doi":"10.1016/j.biopsych.2020.02.1059","title":"Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression: A Multicenter, Factorial Design Randomized Controlled Trial","year":2020,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Bipolar disorder; Depression (economics); Minocycline; Randomized controlled trial; Celecoxib; Medicine; Clinical trial; Adjunctive treatment; Psychiatry; Internal medicine; Cognition","score_opus":0.05525840234418936,"score_gpt":0.29192110354352174,"score_spread":0.2366627011993324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3021255233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987884,0.002546002,0.0012682669,0.00067877414,0.0021473432,0.0049683326,0.000033940705,0.00009503063,0.0003783305],"genre_scores_gemma":[0.9965352,0.0004180415,0.0010976262,0.0012461017,0.0004799312,0.00017482342,0.0000055643336,0.0000110848805,0.000031666706],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9972655,0.0011560888,0.00057116494,0.00056852173,0.00019366342,0.00024502125],"domain_scores_gemma":[0.99763244,0.0017085595,0.00031297916,0.00013323774,0.000022097183,0.00019069367],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002201758,0.00026292144,0.0011480651,0.000042929216,0.000087113665,0.000021423331,0.00020085745,0.00020357726,0.00019027569],"category_scores_gemma":[0.003675174,0.00014470924,0.00038213277,0.00013485037,0.00030102007,0.000058236412,0.000066577995,0.00015347273,0.000018804085],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.95132345,0.00068306166,0.00061019766,0.000007119226,0.00007682812,0.0000032220548,0.00010076016,0.0000018633526,0.046020627,0.00025863637,0.00020279674,0.0007114505],"study_design_scores_gemma":[0.9856048,0.0017466405,0.0003585041,0.00001175698,0.00007217368,0.0000014655324,0.000040470182,0.00028750752,0.010046434,0.0013700428,0.00028497077,0.00017518611],"about_ca_topic_score_codex":0.000009103777,"about_ca_topic_score_gemma":6.677625e-7,"teacher_disagreement_score":0.035974193,"about_ca_system_score_codex":0.000006562466,"about_ca_system_score_gemma":0.000054107848,"threshold_uncertainty_score":0.5901071},"labels":[],"label_agreement":null},{"id":"W3021683292","doi":"10.1016/j.biopsych.2020.02.846","title":"Reelin Concentration-Dependently Rescues Protein Expression Markers of Synaptic-Strength","year":2020,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Reelin; Downregulation and upregulation; PI3K/AKT/mTOR pathway; Synapse; Neuroscience; Antidepressant; Protein expression; Chemistry; Biology; Cell biology; Hippocampus; Signal transduction; Biochemistry; Gene","score_opus":0.04104076701042872,"score_gpt":0.2639799680226225,"score_spread":0.2229392010121938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3021683292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913712,0.0002847904,0.00018635586,0.0036590593,0.000264214,0.00041821203,0.000033741006,0.0001411628,0.0036412587],"genre_scores_gemma":[0.9959817,0.000052473646,0.001899602,0.0018687018,0.00012936356,0.00001660772,0.000006239593,0.000008927971,0.000036405712],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853796,0.00022323747,0.00032652626,0.00047235133,0.00020362649,0.00023627367],"domain_scores_gemma":[0.9994157,0.00010308512,0.0001413086,0.00018152976,0.000018164446,0.00014022124],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008631422,0.00014972438,0.00019052585,0.00001732027,0.00007770267,0.000019201862,0.0003439536,0.00015076272,0.00039807873],"category_scores_gemma":[0.0008264004,0.00010456506,0.00010445632,0.00020210567,0.00020827173,0.00007288991,0.00007778381,0.00018096421,0.00006047651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058872544,0.00016670623,0.0043582297,0.000033459914,0.00000511827,0.000003433946,0.000054966076,0.0000033748152,0.98446023,0.0065801763,0.0030291013,0.0007164873],"study_design_scores_gemma":[0.0024832066,0.0021975231,0.017491912,0.00016816023,0.000008924561,0.0000051591637,0.0008925616,0.00040352132,0.96309626,0.006907129,0.0057349163,0.00061070273],"about_ca_topic_score_codex":0.0000029045884,"about_ca_topic_score_gemma":0.0000013244411,"teacher_disagreement_score":0.021363938,"about_ca_system_score_codex":0.000007106422,"about_ca_system_score_gemma":0.00005029568,"threshold_uncertainty_score":0.4358683},"labels":[],"label_agreement":null},{"id":"W3022414258","doi":"10.1016/j.bbi.2020.04.063","title":"Efficacy of adjunctive infliximab vs. placebo in the treatment of anhedonia in bipolar I/II depression","year":2020,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brain and Cognition Discovery Foundation; University of Ottawa; University Health Network; University of Toronto; Toronto Metropolitan University; Queen's University","funders":"National Cancer Institute; Stanley Medical Research Institute","keywords":"Infliximab; Medicine; Placebo; Internal medicine; Adjunctive treatment; Anhedonia; Randomized controlled trial; Gastroenterology; Tumor necrosis factor alpha","score_opus":0.038632678937813775,"score_gpt":0.2876660171963095,"score_spread":0.24903333825849575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3022414258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983589,0.0004980156,0.000002199891,0.00034987525,0.000023472618,0.00059291534,0.000025109208,0.000011697978,0.0001377938],"genre_scores_gemma":[0.9994451,0.00019805843,0.00001834811,0.0002709093,0.000006082925,0.000037465277,0.0000046346327,0.000008158849,0.000011263658],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988434,0.00039319327,0.00025131312,0.0002030169,0.00015162912,0.00015749865],"domain_scores_gemma":[0.9991333,0.000493632,0.00008800566,0.00023493015,0.0000110682995,0.00003909763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013323514,0.00013247323,0.00023288597,0.000089178364,0.000081174265,0.000009443071,0.00022989922,0.000063011226,0.000020538486],"category_scores_gemma":[0.00031994472,0.00009218708,0.000057851023,0.00040804502,0.00019184862,0.000094602925,0.000071206094,0.00015519766,9.722771e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017088363,0.0041755345,0.15366401,0.00003175949,0.0000037568625,0.000021090194,0.03584098,0.000015522559,0.7441919,0.00010403985,0.00006192694,0.060180664],"study_design_scores_gemma":[0.0047702645,0.0009066697,0.83289635,0.000021888072,0.000009130363,0.0000026831328,0.0007853265,0.000035844903,0.15961403,0.0000139716285,0.00085597637,0.00008787694],"about_ca_topic_score_codex":0.00057446136,"about_ca_topic_score_gemma":0.00009028953,"teacher_disagreement_score":0.67923236,"about_ca_system_score_codex":0.000018946786,"about_ca_system_score_gemma":0.000030017281,"threshold_uncertainty_score":0.375928},"labels":[],"label_agreement":null},{"id":"W3022795538","doi":"10.1038/s41416-020-0874-y","title":"Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion","year":2020,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"National Institute for Health and Care Research; Cancer Research UK; World Health Organization","keywords":"Downregulation and upregulation; Indoleamine 2,3-dioxygenase; Cancer research; Nicotinamide phosphoribosyltransferase; Biology; Kynurenine; Immune system; Immunology; NAD+ kinase; Enzyme; Biochemistry; Gene","score_opus":0.02757297852138995,"score_gpt":0.2764715563612481,"score_spread":0.24889857783985814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3022795538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97386825,0.0066089216,0.00034128237,0.017641507,0.00029981727,0.00039311583,0.000791358,0.000009078202,0.000046643945],"genre_scores_gemma":[0.99745023,0.001082758,0.00016590084,0.0009071651,0.0001993493,0.000020338151,0.0000021555409,0.000018241251,0.00015384285],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988934,0.00006249162,0.00042750884,0.00016912377,0.00029113883,0.00015633277],"domain_scores_gemma":[0.9986666,0.00011184449,0.0007626511,0.00011572892,0.00026971434,0.00007345769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010098329,0.00009592848,0.00025486338,0.000035171597,0.00013572395,0.000019771081,0.00034344796,0.000062528765,0.00008338269],"category_scores_gemma":[0.00043676552,0.00008265563,0.00024382092,0.00030040985,0.000104655664,0.00013247614,0.00006341116,0.00016408949,3.45343e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002683843,0.000047977734,0.001459609,0.000058535083,0.000017239168,0.0000019556273,0.00027757164,0.00048089988,0.9532628,0.000032439275,0.008261678,0.03583089],"study_design_scores_gemma":[0.0017562319,0.00011248831,0.17593104,0.00037631433,0.000028335502,0.0000941948,0.00002825755,0.000343884,0.8134501,0.00024532978,0.0075459024,0.00008789346],"about_ca_topic_score_codex":0.000107381384,"about_ca_topic_score_gemma":0.0005136624,"teacher_disagreement_score":0.17447144,"about_ca_system_score_codex":0.00007029562,"about_ca_system_score_gemma":0.0001970643,"threshold_uncertainty_score":0.3370599},"labels":[],"label_agreement":null},{"id":"W3022964303","doi":"10.1016/j.biopsych.2020.02.253","title":"Neuroinflammation in Mood Disorder: Emerging Biomarkers and Treatment Approaches","year":2020,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Inflammasome; Neuroinflammation; Bipolar disorder; Mitochondrion; Downregulation and upregulation; Protein subunit; Multiprotein complex; Neuroscience; Bipolar II disorder; Mood disorders; Pyrin domain; Cytosol; Psychology; Mood; Cell biology; Inflammation; Medicine; Psychiatry; Biology; Immunology; Biochemistry; Enzyme","score_opus":0.09019337075319342,"score_gpt":0.2605946274218777,"score_spread":0.1704012566686843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3022964303","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98345035,0.0003214182,0.00007613209,0.013725643,0.00012484178,0.00025968434,0.0000054783404,0.00009864883,0.0019377955],"genre_scores_gemma":[0.9984827,0.000247454,0.00035946464,0.000808032,0.00006529305,0.000018573734,0.000004234582,0.000007462507,0.0000067847445],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99899167,0.000112902984,0.0001773756,0.0004508791,0.000066583976,0.00020057165],"domain_scores_gemma":[0.99970865,0.00006553371,0.00004631486,0.00008886272,0.000001786642,0.00008885483],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003932337,0.00014324942,0.00013599453,0.000040919283,0.000069572285,0.00002537361,0.00010715673,0.000073147676,0.000030390502],"category_scores_gemma":[0.0001330315,0.00010033044,0.000049619928,0.0002553135,0.00009972103,0.000063378495,0.000041681553,0.000074257434,0.000019833988],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007176356,0.0009853395,0.67967343,0.00006744873,0.000023037357,0.000016604834,0.0013346316,0.00015260912,0.108818054,0.023353593,0.0003782189,0.18447937],"study_design_scores_gemma":[0.0063235727,0.0025294316,0.9449493,0.000029576395,0.000012970228,0.000019253186,0.0026074701,0.013143304,0.0065883324,0.008619059,0.014177563,0.001000114],"about_ca_topic_score_codex":0.000007647808,"about_ca_topic_score_gemma":0.00003280477,"teacher_disagreement_score":0.2652759,"about_ca_system_score_codex":0.000009478157,"about_ca_system_score_gemma":0.000013905172,"threshold_uncertainty_score":0.40913567},"labels":[],"label_agreement":null},{"id":"W3023009920","doi":"10.1016/j.biopsych.2020.02.134","title":"Single-Cell Genomic Strategies to Understand Psychopathological Processes in Depression and Suicide","year":2020,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Psychopathology; Epigenetics; Major depressive disorder; Depression (economics); Psychology; Neuroscience; Epigenesis; Gene; Clinical psychology; Psychiatry; Biology; Genetics; DNA methylation; Gene expression; Cognition","score_opus":0.08587706629436262,"score_gpt":0.2884161598487127,"score_spread":0.2025390935543501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3023009920","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99053586,0.0010642565,0.00061268377,0.003133604,0.0001462999,0.00029390314,0.000009881382,0.00012562462,0.004077892],"genre_scores_gemma":[0.99041796,0.00014518994,0.0011357168,0.008188332,0.000083608604,0.000008585373,0.0000016183373,0.000010040584,0.000008979016],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998542,0.000108388784,0.00022609858,0.0007053158,0.00010342982,0.00031477047],"domain_scores_gemma":[0.99949265,0.0001421784,0.00005112684,0.00011106852,0.000008582884,0.00019440806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006516761,0.00018563308,0.00019871947,0.00004908342,0.00007917297,0.00008038741,0.00025351657,0.0001523186,0.000058895283],"category_scores_gemma":[0.0003219333,0.00012767507,0.000034093457,0.00038538477,0.00015904912,0.000089744324,0.000111798414,0.00019235442,0.000045238634],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065668015,0.00050474587,0.09089307,0.00010100933,0.0000012815132,0.00003032678,0.0007708141,0.000054396078,0.9024826,0.0017882037,0.0008205144,0.0018963043],"study_design_scores_gemma":[0.0073964424,0.0073357075,0.81317866,0.00022512813,0.000014721712,0.00009308361,0.018633362,0.00014452264,0.068578064,0.073625825,0.008372326,0.00240217],"about_ca_topic_score_codex":0.000002384001,"about_ca_topic_score_gemma":0.000021806993,"teacher_disagreement_score":0.83390456,"about_ca_system_score_codex":0.000012893105,"about_ca_system_score_gemma":0.000051385014,"threshold_uncertainty_score":0.52064383},"labels":[],"label_agreement":null},{"id":"W3023500558","doi":"10.1111/jpi.12667","title":"Melatonin prevents neuroinflammation and relieves depression by attenuating autophagy impairment through FOXO3a regulation","year":2020,"lang":"en","type":"article","venue":"Journal of Pineal Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":324,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Neuroinflammation; Melatonin; Autophagy; SOD2; Lipopolysaccharide; Proinflammatory cytokine; Endocrinology; Internal medicine; Medicine; Biology; Inflammation; Oxidative stress; Superoxide dismutase; Biochemistry; Apoptosis","score_opus":0.09328257283107681,"score_gpt":0.3708419392195771,"score_spread":0.27755936638850026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3023500558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926824,0.00035615807,0.00090087106,0.00524221,0.000067241854,0.00023947688,0.0000030314127,0.000017579474,0.0004910215],"genre_scores_gemma":[0.9985223,0.0002737378,0.0006067275,0.0002553403,0.00015417098,0.0000031211841,0.0000012666395,0.000016258844,0.00016712106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974617,0.000508428,0.0004343272,0.0002447098,0.0010686644,0.00028219225],"domain_scores_gemma":[0.9989538,0.00038386424,0.00026126648,0.00010559421,0.000122025485,0.00017340822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007914135,0.00009992503,0.00016091377,0.000092378796,0.0002276674,0.00010784756,0.00023045197,0.00006107299,0.000052162653],"category_scores_gemma":[0.0022871254,0.000080776146,0.00005452328,0.00037407485,0.00009717721,0.000588417,0.00014064451,0.0004894694,0.000014662493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021622717,0.000064099724,0.00059287506,0.000047582682,0.000004273062,0.000023906474,0.00112013,0.00012508593,0.9787452,0.00017911498,0.0086129485,0.010268522],"study_design_scores_gemma":[0.001900115,0.0013384782,0.02350391,0.00015080498,0.0000060943253,0.00007814022,0.00024140034,0.011693708,0.95501286,0.002366321,0.0035680272,0.00014013537],"about_ca_topic_score_codex":0.0000065932377,"about_ca_topic_score_gemma":5.995968e-7,"teacher_disagreement_score":0.02373237,"about_ca_system_score_codex":0.000048042253,"about_ca_system_score_gemma":0.00008487797,"threshold_uncertainty_score":0.32939556},"labels":[],"label_agreement":null},{"id":"W3023771418","doi":"10.20944/preprints202005.0145.v1","title":"Lowered Antioxidant Defenses and Increased Oxidative Toxicity Are Hallmarks of Deficit Schizophrenia: Neurocognitive and Symptom Correlates","year":2020,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University; Asahi Glass Foundation","keywords":"Oxidative stress; Malondialdehyde; Schizophrenia (object-oriented programming); PON1; Neurocognitive; Paraoxonase; Internal medicine; Medicine; Psychology; Chemistry; Psychiatry; Biochemistry; Cognition; Genotype","score_opus":0.07573614338432867,"score_gpt":0.2970150651419949,"score_spread":0.22127892175766622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3023771418","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955173,0.0003320073,0.000121676865,0.00041017518,0.00021228961,0.0011868047,0.00037243406,0.00021536087,0.0016319228],"genre_scores_gemma":[0.9983851,0.00066976325,0.0001236461,0.00058135844,0.00004423069,0.00007348343,0.000016518918,0.000067508954,0.000038392933],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9959132,0.00048525888,0.0007018182,0.001993506,0.00045535451,0.00045088012],"domain_scores_gemma":[0.9969663,0.0010096158,0.0008443664,0.0006817212,0.0001655981,0.00033238964],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027100058,0.0006618293,0.0009846399,0.00024768166,0.00019391756,0.0000689708,0.00057288446,0.0005580063,0.00013993077],"category_scores_gemma":[0.004692434,0.0006743218,0.00021077202,0.00030321587,0.0008673089,0.00018530965,0.0029407514,0.0016031248,0.00007215265],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010581692,0.00035899403,0.29332235,0.0006457623,0.00011852516,0.000119712335,0.001246128,0.000026075866,0.7014859,0.001182713,0.000014010853,0.00042171095],"study_design_scores_gemma":[0.0011245166,0.000063190935,0.57969475,0.00043023186,0.00007676697,0.000030005398,0.00032311428,0.00024073076,0.4129929,0.0045411983,0.000015262818,0.00046736037],"about_ca_topic_score_codex":0.00013669652,"about_ca_topic_score_gemma":0.00003877356,"teacher_disagreement_score":0.28849298,"about_ca_system_score_codex":0.000036467984,"about_ca_system_score_gemma":0.00016093098,"threshold_uncertainty_score":0.9995708},"labels":[],"label_agreement":null},{"id":"W3025202241","doi":"10.1503/cmaj.190883","title":"Prenatal antibiotic exposure and risk of attention-deficit/hyperactivity disorder: a population-based cohort study","year":2020,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"Manitoba Health","funders":"","keywords":"Medicine; Cohort; Hazard ratio; Cohort study; Population; Attention deficit hyperactivity disorder; Pediatrics; Retrospective cohort study; Pregnancy; Relative risk; Proportional hazards model; Confounding; Confidence interval; Internal medicine; Psychiatry; Environmental health; Biology; Genetics","score_opus":0.008543608684794316,"score_gpt":0.22992203261004257,"score_spread":0.22137842392524826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025202241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953364,0.000038674687,0.000077470904,0.0039002441,0.00018144093,0.00026158104,0.00007026492,0.000017084529,0.00011684601],"genre_scores_gemma":[0.9986199,0.00004456307,0.000018882129,0.0011414265,0.00014132496,0.0000021003373,0.0000052035634,0.0000114787135,0.000015108059],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976351,0.0004892076,0.00034900193,0.00024052642,0.0010265327,0.0002596153],"domain_scores_gemma":[0.99828756,0.00041727215,0.00032695293,0.000077254415,0.000088515226,0.00080246513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066272897,0.000110740475,0.0002250612,0.00010166735,0.00029824674,0.00007127703,0.00016092841,0.00013680737,0.00040340878],"category_scores_gemma":[0.007901741,0.00010307537,0.00007268731,0.0002991578,0.000037173806,0.0001550527,0.000015032994,0.00056063774,0.0000138421765],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009250418,0.00009219035,0.9962159,0.000010764356,0.000030815492,0.00003897986,0.000083580475,0.000032422067,0.00006944407,0.000015278629,0.0001316015,0.0032697706],"study_design_scores_gemma":[0.0012008455,0.00013109948,0.9962658,0.000021431737,0.000029875839,0.000012357215,0.0003721384,0.0016636028,0.00002955263,0.000012990387,0.00015570069,0.00010456641],"about_ca_topic_score_codex":0.0049389983,"about_ca_topic_score_gemma":0.01681636,"teacher_disagreement_score":0.011877364,"about_ca_system_score_codex":0.00013326172,"about_ca_system_score_gemma":0.0005684102,"threshold_uncertainty_score":0.9459693},"labels":[],"label_agreement":null},{"id":"W3025745413","doi":"10.1038/s41398-020-0835-5","title":"Evidence-based umbrella review of 162 peripheral biomarkers for major mental disorders","year":2020,"lang":"en","type":"review","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":213,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Hospital; Simon Fraser University; Women's College Hospital; Mental Health Research Canada; Institute for Clinical Evaluative Sciences; Krembil Foundation; University of Toronto; Sunnybrook Health Science Centre; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; National Health and Medical Research Council; National Institutes of Health; Centro de Investigación Biomédica en Red de Salud Mental; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Department of Health and Social Care; Universidade de São Paulo; Generalitat de Catalunya; National Institute for Health and Care Research; National Alliance for Research on Schizophrenia and Depression; Alzheimer Society; Stanley Medical Research Institute; Ministerio de Ciencia, Innovación y Universidades; Medical Research Council; Beyond Blue; National Institute on Aging; Alzheimer's Association","keywords":"Schizophrenia (object-oriented programming); Biomarker; Bipolar disorder; Meta-analysis; Psychosis; Major depressive disorder; Clinical psychology; Systematic review; Psychiatry; Medicine; Disease; Psychology; Internal medicine; MEDLINE; Mood; Genetics; Biology","score_opus":0.10524463950822274,"score_gpt":0.3655277197099807,"score_spread":0.26028308020175794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025745413","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[9.94081e-7,0.9841198,0.0008116199,0.008968277,0.001108093,0.003113937,0.0010015694,0.00007581999,0.0007999368],"genre_scores_gemma":[0.000020489097,0.99353886,0.0028816762,0.0026815855,0.00019624668,0.00025224392,0.00027028532,0.00009430154,0.00006432167],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967678,0.00030008663,0.0010864905,0.0008707659,0.0006252919,0.00034956096],"domain_scores_gemma":[0.9981937,0.00074499263,0.0005330264,0.00034375186,0.00003505046,0.00014952545],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002445421,0.00056637486,0.0013357566,0.00016203837,0.0001473173,0.000028470018,0.00067818345,0.00022020539,0.0007008303],"category_scores_gemma":[0.0001934651,0.00050001254,0.0017182714,0.00078368944,0.00024183682,0.00016923597,0.00001832223,0.00026925848,0.000040218714],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014139096,0.00020413542,0.000012635548,0.2603787,0.00012465824,6.3611117e-7,0.000025650741,0.0000022276738,0.00002429328,0.0024390419,0.014475489,0.7221712],"study_design_scores_gemma":[0.0008043168,0.00013117852,0.000009973334,0.10568798,0.00038153428,0.0000057372577,0.0000055142273,0.00006374789,0.00000799911,0.00071264536,0.8916946,0.00049479236],"about_ca_topic_score_codex":0.0000040835857,"about_ca_topic_score_gemma":0.000012266173,"teacher_disagreement_score":0.8772191,"about_ca_system_score_codex":0.000041998963,"about_ca_system_score_gemma":0.0012717154,"threshold_uncertainty_score":0.99974513},"labels":[],"label_agreement":null},{"id":"W3025932015","doi":"10.1016/j.tem.2020.04.008","title":"The Dual Role of Serotonin in Colorectal Cancer","year":2020,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":78,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Serotonergic; Colorectal cancer; Serotonin; Biology; Cancer; Immune system; Cancer research; Homeostasis; Carcinogenesis; Neuroscience; Internal medicine; Medicine; Endocrinology; Immunology; Receptor","score_opus":0.03874566978560338,"score_gpt":0.33568992527710295,"score_spread":0.29694425549149955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025932015","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003596133,0.9931312,6.655758e-8,0.00018606767,0.00036096675,0.00025681735,0.00006320306,0.000022927201,0.0023826056],"genre_scores_gemma":[0.0063407025,0.9929958,0.000008238483,0.0000653763,0.00006419769,0.00029370107,0.0000041653266,0.000022441112,0.00020540775],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997953,0.00046497112,0.00049293606,0.00049430324,0.00011552869,0.00047926858],"domain_scores_gemma":[0.9991258,0.0004516785,0.00020351018,0.00016164096,0.00000644917,0.0000509431],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000079826656,0.0002973134,0.0011904262,0.0003535116,0.000064267886,0.000012874341,0.00035503466,0.0001792672,0.000059136575],"category_scores_gemma":[0.00016578879,0.00020016923,0.00015536661,0.0007808936,0.00046510695,0.00004830959,0.00019419943,0.00067334477,0.000007397463],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002455022,0.00003542311,0.00002431523,0.00016620362,0.000014796168,0.00004943329,0.00022120155,5.2604605e-7,0.00016887703,0.013784822,0.00004092652,0.9854689],"study_design_scores_gemma":[0.00056273316,0.000020672942,0.0010553062,0.00019229564,0.000050042294,0.00006343148,0.000057898775,0.000004664606,0.0012777871,0.00039881843,0.996139,0.00017738246],"about_ca_topic_score_codex":0.00009915302,"about_ca_topic_score_gemma":0.00050389837,"teacher_disagreement_score":0.99609804,"about_ca_system_score_codex":0.000019612251,"about_ca_system_score_gemma":0.00010660539,"threshold_uncertainty_score":0.8162664},"labels":[],"label_agreement":null},{"id":"W3026093439","doi":"10.1093/schbul/sbaa029.581","title":"T21. DEVELOPMENT OF PROTEOMIC PREDICTION MODELS FOR OUTCOMES IN THE CLINICAL HIGH RISK STATE AND PSYCHOTIC EXPERIENCES IN ADOLESCENCE: MACHINE LEARNING ANALYSES IN TWO NESTED CASE-CONTROL STUDIES","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ste. Anne's Hospital","funders":"","keywords":"Psychosis; Subclinical infection; Psychology; Body mass index; Schizophrenia (object-oriented programming); Clinical psychology; Psychiatry; Internal medicine; Medicine","score_opus":0.09774448993260759,"score_gpt":0.3676082238551529,"score_spread":0.2698637339225453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026093439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963226,0.00034585746,0.0006819028,0.0013562934,0.000071255236,0.0011727399,0.000022718188,0.000023443828,0.0000032035405],"genre_scores_gemma":[0.9967123,0.00015691711,0.0024404281,0.00032933685,0.000018010272,0.0003233244,0.0000013558514,0.00001231999,0.0000060076877],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9973688,0.0008046218,0.0008331171,0.00051406655,0.0002170913,0.00026231364],"domain_scores_gemma":[0.9986325,0.00092185347,0.0002502649,0.0001206489,0.000024053941,0.000050687646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008861403,0.00019529615,0.00046766977,0.00015642516,0.00012315955,0.000032554024,0.00021522312,0.000042945947,0.0000094608295],"category_scores_gemma":[0.0017574343,0.00013489982,0.00005887378,0.00039159987,0.00020263375,0.000079869984,0.000049650844,0.00040570967,0.0000026111377],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011554599,0.0011196989,0.74679816,0.0003842929,0.000108415275,0.0002938331,0.13963625,0.05887751,0.008221953,0.00017414053,0.00009390522,0.032737236],"study_design_scores_gemma":[0.039587237,0.0011264589,0.7422195,0.00043041454,0.00006778235,0.000046058376,0.037564546,0.16936332,0.005962098,0.0027407277,0.00006645212,0.00082540535],"about_ca_topic_score_codex":0.00013865772,"about_ca_topic_score_gemma":0.00078781025,"teacher_disagreement_score":0.11048581,"about_ca_system_score_codex":0.000019339863,"about_ca_system_score_gemma":0.000059216945,"threshold_uncertainty_score":0.5501055},"labels":[],"label_agreement":null},{"id":"W3026565579","doi":"10.1093/schbul/sbaa031.287","title":"S221. THE EFFICACY OF LUMATEPERONE 42 MG IN THE TREATMENT OF SCHIZOPHRENIA SYMPTOMS ASSOCIATED WITH SOCIAL FUNCTIONING: POST HOC ANALYSIS OF AN ACUTE PLACEBO- AND ACTIVE-CONTROLLED TRIAL","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Risperidone; Positive and Negative Syndrome Scale; Psychology; Post-hoc analysis; Psychiatry; Exacerbation; Placebo; Population; Clinical psychology; Internal medicine; Medicine; Psychosis","score_opus":0.016639079537900066,"score_gpt":0.24619159037068147,"score_spread":0.22955251083278141,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026565579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951846,0.00007859003,0.000007214317,0.002681138,0.000060008308,0.0016651422,0.00016245923,0.00003714547,0.00012369548],"genre_scores_gemma":[0.999421,0.000040818995,0.000059937363,0.00020160746,0.000079247184,0.000106447136,0.00003589978,0.000025788422,0.00002923778],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99692005,0.0010009155,0.00065381767,0.000529688,0.0005827445,0.00031275593],"domain_scores_gemma":[0.99740696,0.0014006192,0.0006887999,0.0003368837,0.00008707619,0.00007965123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035803946,0.00032706218,0.0010573358,0.00024312263,0.00023853449,0.00005275195,0.0004443524,0.00012972573,0.00016569451],"category_scores_gemma":[0.0005484446,0.00018465877,0.0003495759,0.0014927932,0.0005383689,0.000070537346,0.00004457323,0.00021775742,0.000003841835],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9371502,0.0021424815,0.00012981996,0.000012858056,0.001780446,0.000013081383,0.008994238,0.00024192447,0.043898065,0.0005341699,0.00004892218,0.0050538015],"study_design_scores_gemma":[0.8558852,0.019850327,0.09647816,0.000054414148,0.004116103,0.0000052799437,0.0029746757,0.0019162071,0.017861633,0.000058122616,0.00018662261,0.0006132493],"about_ca_topic_score_codex":0.00007212298,"about_ca_topic_score_gemma":0.00019467654,"teacher_disagreement_score":0.09634834,"about_ca_system_score_codex":0.000039359285,"about_ca_system_score_gemma":0.00012064618,"threshold_uncertainty_score":0.7530166},"labels":[],"label_agreement":null},{"id":"W3026718622","doi":"10.1093/schbul/sbaa029.567","title":"T7. UPDATED INDIVIDUAL PARTICIPANT DATA META-ANALYSIS CONFIRMS LOWER LEVELS OF THE GLIAL MARKER TSPO IN PSYCHOSIS PATIENTS","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Translocator protein; Psychosis; Radioligand; Temporal cortex; Internal medicine; Positron emission tomography; Psychology; Antipsychotic; Binding potential; Schizophrenia (object-oriented programming); Meta-analysis; Medicine; Neuroscience; Oncology; Psychiatry; Receptor; Disease; Neuroinflammation","score_opus":0.1891132141457913,"score_gpt":0.30836624968970267,"score_spread":0.11925303554391137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026718622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9790631,0.00017427895,0.000027340053,0.016465899,0.0002758293,0.00061703636,0.00293793,0.000059588627,0.00037899055],"genre_scores_gemma":[0.99454087,0.0000048448906,0.0002585641,0.0049380427,0.000031017356,0.000025861931,0.00006399773,0.00002709845,0.000109727174],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9964055,0.0006267705,0.00073076546,0.00096182793,0.00081892055,0.00045625572],"domain_scores_gemma":[0.99801224,0.0002232599,0.00032745735,0.0012248147,0.000049962953,0.00016227215],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00043843023,0.00030281022,0.00079929794,0.00014176575,0.00010584823,0.00007915129,0.0019999759,0.00011263762,0.009479856],"category_scores_gemma":[0.0011270833,0.00020346433,0.00053393183,0.0017653633,0.00027002234,0.00009769255,0.00076736865,0.00035825442,0.0002271665],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.026771149,0.013045819,0.09413054,0.00037852745,0.15942803,0.00022613393,0.014109193,0.0030675947,0.08681499,0.006377751,0.57951564,0.016134629],"study_design_scores_gemma":[0.013958095,0.0005032261,0.7493571,0.000027008107,0.09067417,0.0000030401104,0.00040930565,0.0019630098,0.05110181,0.0005310142,0.089512825,0.0019594145],"about_ca_topic_score_codex":0.000082704355,"about_ca_topic_score_gemma":0.0001318104,"teacher_disagreement_score":0.6552265,"about_ca_system_score_codex":0.000006652649,"about_ca_system_score_gemma":0.000056533467,"threshold_uncertainty_score":0.99142563},"labels":[],"label_agreement":null},{"id":"W3026762001","doi":"10.1093/schbul/sbaa030.322","title":"M10. SERUM AND CLINICAL MARKERS ASSOCIATED WITH MEMBRANE PUFA CONTENT IN A POPULATION OF STABILISED AND TREATED SCHIZOPHRENIA OUTPATIENTS","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Population; Biomarker; Schizophrenia (object-oriented programming); Polyunsaturated fatty acid; Psychopathology; Internal medicine; Medicine; Psychiatry; Fatty acid; Biology; Biochemistry","score_opus":0.040086215666686936,"score_gpt":0.24926682421731508,"score_spread":0.20918060855062814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026762001","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99625784,0.00006794086,0.000002550438,0.0025937601,0.000055823562,0.00067767384,0.00008666376,0.00008736013,0.00017038167],"genre_scores_gemma":[0.99881965,0.00006441983,0.00022530001,0.0007465223,0.00002046762,0.000014824566,0.000022871562,0.000035602527,0.000050352584],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99741066,0.00049830956,0.00067484664,0.0007297027,0.00035337254,0.0003331229],"domain_scores_gemma":[0.9987274,0.00047417168,0.00030675897,0.00019446341,0.00005142232,0.00024579282],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031120883,0.00027986968,0.00054290687,0.00011843426,0.00008264973,0.00005021273,0.00016814868,0.00015962403,0.00014730442],"category_scores_gemma":[0.00212242,0.00023745625,0.000069802176,0.0004344965,0.0003133976,0.00007920732,0.00010433307,0.00033465726,0.00001051616],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03315988,0.0008997348,0.93118626,0.00017925582,0.00009674969,0.00007382359,0.00056017184,0.00002784472,0.019112963,0.00039591052,0.00047954704,0.013827854],"study_design_scores_gemma":[0.015646668,0.00090630195,0.9782282,0.00015455973,0.000033778197,0.000003506383,0.00012742808,0.00069609634,0.0036987194,0.00005383976,0.00012646177,0.00032445358],"about_ca_topic_score_codex":0.00019170324,"about_ca_topic_score_gemma":0.00027194797,"teacher_disagreement_score":0.047041923,"about_ca_system_score_codex":0.000028507215,"about_ca_system_score_gemma":0.000038438877,"threshold_uncertainty_score":0.9683185},"labels":[],"label_agreement":null},{"id":"W3026897301","doi":"10.1093/schbul/sbaa029.756","title":"T196. THERAPEUTIC MANAGEMENT IN MULTIPLE SCLEROSIS AND SCHIZOPHRENIA SPECTRUM DISORDERS DUAL DIAGNOSIS","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Schizoaffective disorder; Positive and Negative Syndrome Scale; Multiple sclerosis; Psychiatry; Psychosis; Psychology; Global Assessment of Functioning; Synaptic pruning; Brief Psychiatric Rating Scale; Clinical psychology; Medicine; Internal medicine","score_opus":0.03579749125006799,"score_gpt":0.22467278997567172,"score_spread":0.18887529872560374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026897301","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9428044,0.0010494734,0.00012279133,0.052358635,0.00024674984,0.0010466822,0.000041335716,0.0003455585,0.001984378],"genre_scores_gemma":[0.9911447,0.0021933857,0.0011709305,0.004988191,0.00011999693,0.00021366276,0.000005395764,0.00007606951,0.00008764774],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9969154,0.0002423471,0.0004928946,0.001173033,0.0004456686,0.0007306671],"domain_scores_gemma":[0.9988265,0.0003604975,0.00012815864,0.00037553182,0.000006927031,0.00030239893],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016600311,0.00045437223,0.000391608,0.00022951297,0.00027155923,0.00018286318,0.00045752828,0.00012620348,0.00082148216],"category_scores_gemma":[0.0002662122,0.0004501243,0.00013435482,0.0007948178,0.00031827376,0.00011880882,0.00035706037,0.00045224917,0.00070226914],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019629702,0.0033774069,0.044835676,0.0009344174,0.00034175604,0.000714876,0.0052640047,0.000862183,0.083776586,0.1001025,0.029668102,0.7104928],"study_design_scores_gemma":[0.066465504,0.0018145059,0.5036658,0.0006109958,0.00020212567,0.00004886818,0.0020722896,0.0046700314,0.13747455,0.033826657,0.24338892,0.0057597216],"about_ca_topic_score_codex":0.000072165225,"about_ca_topic_score_gemma":0.00019288984,"teacher_disagreement_score":0.7047331,"about_ca_system_score_codex":0.000038835693,"about_ca_system_score_gemma":0.000025036166,"threshold_uncertainty_score":0.9997951},"labels":[],"label_agreement":null},{"id":"W3027027184","doi":"10.1093/schbul/sbaa030.528","title":"M216. ASSOCIATIONS OF EXTRAPYRAMIDAL SYMPTOMS WITH PSYCHOTIC SYMPTOMS IN A COHORT OF HOMELESS OR PRECARIOUSLY HOUSED PERSONS WITH OR WITHOUT SCHIZOPHRENIA","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Akathisia; Positive and Negative Syndrome Scale; Extrapyramidal symptoms; Schizophrenia (object-oriented programming); Rating scale; Parkinsonism; Psychiatry; Psychology; Dyskinesia; Confounding; Clinical psychology; Cohort; Antipsychotic; Psychosis; Depression (economics); Internal medicine; Medicine","score_opus":0.02364112345243185,"score_gpt":0.2531834707414479,"score_spread":0.22954234728901607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3027027184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99549174,0.0000751137,0.0002505855,0.0015394457,0.00009069301,0.0014993283,0.00023551435,0.00024704414,0.00057053537],"genre_scores_gemma":[0.9961721,0.00003252477,0.0025832034,0.0005311078,0.000072166156,0.00014285877,0.000015315785,0.00013313376,0.00031759907],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99597055,0.00032661395,0.0008296574,0.001115622,0.0010262999,0.000731256],"domain_scores_gemma":[0.9977884,0.00048530355,0.0006622345,0.00061854685,0.0001262938,0.00031917167],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023097116,0.00058218266,0.001201326,0.00034807407,0.0001630574,0.00008665246,0.00083989906,0.00023019173,0.0005436808],"category_scores_gemma":[0.00049612555,0.00040250111,0.00015858158,0.0020478498,0.0007288281,0.00015158753,0.00009273487,0.0006291653,0.000048043064],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.19963624,0.0052270535,0.57655895,0.0014698107,0.0011904967,0.00062049966,0.022297906,0.0025283878,0.17175591,0.005306983,0.0028065995,0.010601177],"study_design_scores_gemma":[0.11134137,0.018010309,0.7443202,0.0025284782,0.0008043118,0.0003238955,0.003610804,0.0038430933,0.10778721,0.0002254183,0.0024052982,0.0047995984],"about_ca_topic_score_codex":0.00021523112,"about_ca_topic_score_gemma":0.0015605363,"teacher_disagreement_score":0.16776127,"about_ca_system_score_codex":0.00007666949,"about_ca_system_score_gemma":0.00067315705,"threshold_uncertainty_score":0.9998427},"labels":[],"label_agreement":null},{"id":"W3028000822","doi":"10.1093/schbul/sbaa029.576","title":"T16. SCHIZOPHRENIA SPECTRUM DISORDER: DEPRESSION TRAJECTORIES AND IMMUNE MARKERS","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Positive and Negative Syndrome Scale; Schizophrenia (object-oriented programming); Amisulpride; Depression (economics); Population; Psychiatry; Major depressive disorder; Internal medicine; Psychology; Medicine; Clinical psychology; Olanzapine; Psychosis; Cognition","score_opus":0.011656827700638603,"score_gpt":0.21422362139200668,"score_spread":0.20256679369136807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3028000822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9682875,0.0022069737,0.00016800799,0.022745008,0.0003382444,0.00055901246,0.000052425527,0.0006058705,0.0050369212],"genre_scores_gemma":[0.99513996,0.0004889341,0.0013265235,0.0019382172,0.0002806882,0.00003688043,0.000009810274,0.00008410481,0.0006948988],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99702686,0.00024430625,0.0005053701,0.001102831,0.00046629054,0.000654325],"domain_scores_gemma":[0.99873465,0.00026219565,0.0001550884,0.00043283447,0.000018646211,0.00039656894],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00016353761,0.0004727455,0.00044562216,0.000090689115,0.00047901022,0.00021710877,0.00056499144,0.0001668877,0.0038031058],"category_scores_gemma":[0.0007797328,0.00043343424,0.0001659833,0.000515876,0.00039988555,0.00015000066,0.00025715758,0.0005165418,0.0010049172],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.030812565,0.0007038981,0.0053737485,0.00054136734,0.00012094841,0.00039065693,0.0025539473,0.00017385789,0.5652713,0.01708514,0.040200993,0.33677155],"study_design_scores_gemma":[0.026842749,0.001462103,0.08746518,0.0003299653,0.000115980816,0.0002328879,0.0011563068,0.0014662255,0.379156,0.007591647,0.49023476,0.003946202],"about_ca_topic_score_codex":0.0000750816,"about_ca_topic_score_gemma":0.000023012015,"teacher_disagreement_score":0.45003375,"about_ca_system_score_codex":0.000020626061,"about_ca_system_score_gemma":0.000058751946,"threshold_uncertainty_score":0.99981177},"labels":[],"label_agreement":null},{"id":"W3028537003","doi":"10.1016/s2215-0366(20)30138-3","title":"Minocycline and celecoxib as adjunctive treatments for bipolar depression: a multicentre, factorial design randomised controlled trial","year":2020,"lang":"en","type":"article","venue":"The Lancet Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":166,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Newcastle upon Tyne Hospitals NHS Foundation Trust; Centre for Addiction and Mental Health Foundation; Fondation Brain Canada; Canadian Institutes of Health Research; National Institute for Health and Care Research; National Institutes of Health; Stanley Medical Research Institute; King's College London; Patient-Centered Outcomes Research Institute","keywords":"Celecoxib; Placebo; Minocycline; Medicine; Bipolar I disorder; Clinical trial; Depression (economics); Bipolar disorder; Randomized controlled trial; Internal medicine; Psychiatry; Mania; Lithium (medication)","score_opus":0.05850990761081344,"score_gpt":0.30028675720818676,"score_spread":0.24177684959737333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3028537003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9381483,0.005412126,0.007414845,0.014341703,0.008412276,0.024561817,0.00018981427,0.00038301418,0.0011360684],"genre_scores_gemma":[0.97933793,0.0005884582,0.0024795406,0.009340208,0.0067569893,0.0011495051,0.00001277063,0.000059086186,0.00027548237],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9982221,0.0004181101,0.00030168108,0.00048096495,0.00020975115,0.00036735114],"domain_scores_gemma":[0.9979051,0.0014848952,0.00019736493,0.00024381265,0.000020200709,0.00014863459],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018730256,0.0002480438,0.000607432,0.000027338476,0.0002593743,0.00006841133,0.0003067522,0.00009325254,0.00006844665],"category_scores_gemma":[0.0013249064,0.00014578136,0.00019699424,0.00012936567,0.00008844821,0.00009565536,0.00004014897,0.00016124584,0.000022180306],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.97399014,0.000301386,0.00020407738,0.000017620088,0.00011904656,0.0000019592696,0.0007270792,0.000017666578,0.015373156,0.00023549583,0.0069301846,0.0020822152],"study_design_scores_gemma":[0.9820486,0.0008209015,0.00017982427,0.000012805082,0.00017018069,0.0000023343239,0.0000949004,0.0016183027,0.007631663,0.0019012633,0.005311576,0.00020767486],"about_ca_topic_score_codex":0.0000062179047,"about_ca_topic_score_gemma":0.0000047175995,"teacher_disagreement_score":0.041189622,"about_ca_system_score_codex":0.000009751607,"about_ca_system_score_gemma":0.00008833797,"threshold_uncertainty_score":0.59447914},"labels":[],"label_agreement":null},{"id":"W3033172924","doi":"10.1192/bjo.2020.43","title":"Inflammation as a treatment target in mood disorders: review","year":2020,"lang":"en","type":"article","venue":"BJPsych Open","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Department of Psychiatry, University of Toronto; University of Toronto; King's College London; National Institute for Health and Care Research; South London and Maudsley NHS Foundation Trust","keywords":"Mood disorders; Major depressive disorder; Bipolar disorder; Mood; Medicine; Psychiatry; Clinical trial; Randomized controlled trial; Clinical psychology; Psychology; Anxiety; Internal medicine","score_opus":0.06129781268361028,"score_gpt":0.33739259970181196,"score_spread":0.27609478701820167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033172924","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17884277,0.0040849787,0.00015634431,0.21996239,0.0003105785,0.012532913,0.00003411109,0.00025200777,0.5838239],"genre_scores_gemma":[0.9716455,0.0101411445,0.0004989139,0.01567639,0.000080078375,0.00057591393,0.000017977814,0.00003253335,0.0013315728],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99896646,0.00009969983,0.00022268668,0.00038212838,0.00014247307,0.00018657782],"domain_scores_gemma":[0.99958754,0.00004157235,0.00006735315,0.00020790244,0.000006240362,0.00008940732],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007796927,0.00013056911,0.00020291901,0.000029280574,0.000048090566,0.00008088309,0.00047513685,0.000031000858,0.00079644425],"category_scores_gemma":[0.00028521687,0.00010973719,0.00005020397,0.000423328,0.000025315823,0.00031006092,0.000103317005,0.00006387466,0.0008597337],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080088264,0.0018186137,0.008333145,0.0013472383,0.0000393939,0.00007033699,0.0075488277,0.00019109734,0.07817798,0.026779812,0.039612383,0.8352803],"study_design_scores_gemma":[0.004253377,0.0007726595,0.0048977826,0.0004984434,0.000009634079,0.0000053075196,0.0001984153,0.00042594707,0.030238401,0.0072344714,0.950994,0.0004715741],"about_ca_topic_score_codex":0.00009507071,"about_ca_topic_score_gemma":0.00018549114,"teacher_disagreement_score":0.9113816,"about_ca_system_score_codex":0.000029372468,"about_ca_system_score_gemma":0.00005781,"threshold_uncertainty_score":0.9999182},"labels":[],"label_agreement":null},{"id":"W3033827278","doi":"10.1139/apnm-2020-0099","title":"Anxiolytic and antioxidant effects of <i>Euterpe oleracea</i> Mart. (açaí) seed extract in adult rat offspring submitted to periodic maternal separation","year":2020,"lang":"en","type":"article","venue":"Applied Physiology Nutrition and Metabolism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Open field; Internal medicine; Endocrinology; Tropomyosin receptor kinase B; Elevated plus maze; Anxiolytic; Behavioural despair test; Hypothalamic–pituitary–adrenal axis; Neurotrophic factors; Medicine; Hippocampus; Receptor; Hormone; Anxiety; Antidepressant","score_opus":0.008859206969729656,"score_gpt":0.23499701275298446,"score_spread":0.2261378057832548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033827278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99819416,0.00031670282,0.00009085942,0.00050594856,0.00011728274,0.0006633436,0.000008936516,0.00004455476,0.00005819557],"genre_scores_gemma":[0.99472684,0.00075714634,0.00021889093,0.0041029705,0.00007692472,0.00009032355,0.0000061344567,0.000014610287,0.0000061699434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883926,0.00008392001,0.00026491232,0.00046104123,0.000111507325,0.00023935991],"domain_scores_gemma":[0.9995376,0.00010729767,0.00009433317,0.00010859643,0.000021350072,0.00013083745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004998205,0.0001831219,0.00036598323,0.0001161087,0.00007133459,0.00003237345,0.000094846735,0.00008861373,0.000010093151],"category_scores_gemma":[0.000060031656,0.00017599676,0.00003768103,0.00027461202,0.00012541813,0.00013275871,0.000060910785,0.00014944414,0.000010806121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024929823,0.00011131213,0.00017293224,0.00023335376,0.0000044306294,0.0000047209683,0.0005463101,0.0000061341343,0.9942165,0.0025952652,0.00004625472,0.0018135061],"study_design_scores_gemma":[0.0029468585,0.00003218266,0.33524227,0.000042771237,0.00001073483,0.0000052723617,0.000077092656,0.00032213,0.6597686,0.00039495158,0.0010055276,0.00015161656],"about_ca_topic_score_codex":0.000009719248,"about_ca_topic_score_gemma":0.0000031583759,"teacher_disagreement_score":0.33506933,"about_ca_system_score_codex":0.0000053841713,"about_ca_system_score_gemma":0.000012556938,"threshold_uncertainty_score":0.7176939},"labels":[],"label_agreement":null},{"id":"W3033945637","doi":"10.1186/s13063-020-04365-4","title":"Prednisolone versus placebo addition in the treatment of patients with recent-onset psychotic disorder: a trial design","year":2020,"lang":"en","type":"article","venue":"Trials","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Stanley Medical Research Institute","keywords":"Prednisolone; Medicine; Schizophrenia (object-oriented programming); Schizoaffective disorder; Placebo; Antipsychotic; Internal medicine; Randomized controlled trial; Schizophreniform disorder; Psychosis; Psychiatry; Pathology","score_opus":0.20334251292234834,"score_gpt":0.349790135626021,"score_spread":0.14644762270367268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033945637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99175215,0.00006712146,0.00033081687,0.0014442772,0.00036715952,0.005570977,0.00020276931,0.000040243216,0.00022450008],"genre_scores_gemma":[0.99872965,0.00035873748,0.00013884119,0.0002990095,0.00008392758,0.0003273539,0.000037692804,0.000014721437,0.000010091022],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9971662,0.0015776524,0.0004445427,0.00030844356,0.00031121488,0.0001919343],"domain_scores_gemma":[0.9966268,0.0028407527,0.0002568846,0.00021004009,0.000016835722,0.000048678772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003751061,0.00015396354,0.0003857163,0.000050012535,0.0000563594,0.000027787342,0.00020010945,0.000050133338,0.00025045435],"category_scores_gemma":[0.0022208714,0.000089366564,0.0000815989,0.0004228455,0.0000823471,0.00007618679,0.000006556477,0.00005491002,0.000027503256],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9618739,0.0036389984,0.00020671035,0.000015205863,0.000037552672,0.0000067332403,0.003959985,0.00022107079,0.0008846315,0.00009022789,0.0036040384,0.025460958],"study_design_scores_gemma":[0.9068069,0.05033207,0.004056033,0.000039966726,0.00015295453,7.539746e-7,0.0006540418,0.00022615095,0.018296326,0.0005611159,0.018414667,0.00045905772],"about_ca_topic_score_codex":0.0000083350415,"about_ca_topic_score_gemma":0.000016013577,"teacher_disagreement_score":0.055067025,"about_ca_system_score_codex":0.000026676236,"about_ca_system_score_gemma":0.00005683279,"threshold_uncertainty_score":0.36442629},"labels":[],"label_agreement":null},{"id":"W3035256952","doi":"10.3389/fnmol.2020.00096","title":"Melatonin Act as an Antidepressant via Attenuation of Neuroinflammation by Targeting Sirt1/Nrf2/HO-1 Signaling","year":2020,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"Neuroinflammation; Luzindole; Melatonin; Oxidative stress; Lipopolysaccharide; Sickness behavior; Inflammation; Endocrinology; Pharmacology; Medicine; Internal medicine; Melatonin receptor","score_opus":0.013363267601736574,"score_gpt":0.24023778071592358,"score_spread":0.22687451311418702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035256952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8815472,0.00010097988,0.11666342,0.0005322358,0.00044252427,0.0003842177,0.0000127214025,0.000095625786,0.00022104249],"genre_scores_gemma":[0.99535596,0.00004147246,0.0023772158,0.0021361387,0.000021621996,0.000009816448,0.000011142337,0.00003792708,0.000008713237],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99681,0.0004380736,0.0005205707,0.000988689,0.00076598994,0.00047667974],"domain_scores_gemma":[0.99907,0.00006530083,0.0003108932,0.0003065011,0.000034669967,0.00021265748],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028593457,0.00025339163,0.00029208424,0.00018037333,0.00015811829,0.00010305477,0.00078280433,0.00008536968,0.000012246687],"category_scores_gemma":[0.0018714267,0.0002738109,0.000074306714,0.0011515798,0.00031304068,0.0007638099,0.00012664056,0.00031083726,0.000007720337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045311637,0.00007865073,0.0018656731,0.000023665258,7.737737e-7,0.0000730397,0.000404062,0.00647946,0.9888673,0.00014463231,0.0003946192,0.001622818],"study_design_scores_gemma":[0.0004168922,0.00022628123,0.00068457384,0.000015033526,0.000004787652,0.000006289644,0.00009718595,0.10824457,0.88925004,0.00042713573,0.00038482292,0.00024236398],"about_ca_topic_score_codex":0.000020505611,"about_ca_topic_score_gemma":4.2579273e-7,"teacher_disagreement_score":0.1142862,"about_ca_system_score_codex":0.000025263098,"about_ca_system_score_gemma":0.00007024398,"threshold_uncertainty_score":0.9999714},"labels":[],"label_agreement":null},{"id":"W3037455856","doi":"10.1093/schizbullopen/sgaa032","title":"Patient Stratification Using Metabolomics to Address the Heterogeneity of Psychosis","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Bulletin Open","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Fondation de l'Hôpital de Montréal pour enfants; Children's Hospital Foundation","keywords":"Cluster analysis; Psychosis; Metabolomics; Hierarchical clustering; Cluster (spacecraft); Identification (biology); Computational biology; Bioinformatics; Psychology; Medicine; Computer science; Biology; Psychiatry; Machine learning","score_opus":0.07218411870358235,"score_gpt":0.30850998832691323,"score_spread":0.23632586962333088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037455856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9828722,0.00005671748,0.00030459254,0.014109722,0.00015173783,0.001117436,0.000070907015,0.000030613748,0.0012861063],"genre_scores_gemma":[0.9897316,0.000013725059,0.0038058232,0.006321106,0.00004258773,0.000048210906,0.0000026016758,0.000019817362,0.000014530421],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854255,0.0002303993,0.0003203355,0.0004536028,0.00025664273,0.00019648817],"domain_scores_gemma":[0.99913853,0.00010408068,0.00017218268,0.0004150872,0.000040826235,0.00012927027],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014358875,0.00014538619,0.00020215235,0.00002991648,0.00018420555,0.00015858129,0.0010356428,0.000043006003,0.00034067951],"category_scores_gemma":[0.00039951343,0.00010900185,0.000072821305,0.000374372,0.00009150872,0.0000663312,0.00038437062,0.00012908208,0.00014841069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015580663,0.00019491605,0.00011509659,0.000027692118,0.000023365625,0.0000032428197,0.00159391,0.00130236,0.9573848,0.0055011837,0.013771297,0.018524045],"study_design_scores_gemma":[0.00085803296,0.0001745227,0.0010843896,0.000022627975,0.000017120816,0.000003884132,0.00029813114,0.0004616325,0.94446945,0.00026738513,0.05209591,0.00024692676],"about_ca_topic_score_codex":0.0000907809,"about_ca_topic_score_gemma":0.000020327952,"teacher_disagreement_score":0.03832461,"about_ca_system_score_codex":0.000011190226,"about_ca_system_score_gemma":0.00004012097,"threshold_uncertainty_score":0.44449663},"labels":[],"label_agreement":null},{"id":"W3037573044","doi":"10.1038/s41598-020-67271-4","title":"Sex dependent effects of post-natal penicillin on brain, behavior and immune regulation are prevented by concurrent probiotic treatment","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Canadian Institutes of Health Research; Azrieli Foundation; Israel Science Foundation; International Development Research Centre","keywords":"Antibiotics; Penicillin; Weaning; Immune system; Probiotic; Physiology; Medicine; Biology; Internal medicine; Immunology; Microbiology; Bacteria","score_opus":0.015922170662570068,"score_gpt":0.24963965092838092,"score_spread":0.23371748026581085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037573044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961255,0.00026862478,0.000034430293,0.0007167248,0.0012693523,0.0014269153,0.000029386532,0.00006460114,0.000064465894],"genre_scores_gemma":[0.99798805,0.000006346591,0.000011763268,0.00015032566,0.000015014935,0.00004684897,0.000060691655,0.000016112599,0.0017048245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997785,0.00012497196,0.00044745416,0.00091067096,0.0004933606,0.00023859068],"domain_scores_gemma":[0.9988082,0.00016180365,0.00043111684,0.000395139,0.00005536007,0.00014836609],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019334198,0.00019562726,0.00026086508,0.0000804427,0.00017528741,0.0001081267,0.000110448156,0.000057915797,0.000048077614],"category_scores_gemma":[0.00077033404,0.00016206843,0.00009350903,0.0002651932,0.00025474664,0.00012505912,0.00006884196,0.00008122823,0.000010275725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024647858,0.00044341738,0.00056884054,0.00009650609,0.0000063353878,0.00018438105,0.00066715846,0.000015515132,0.9904866,0.00002377268,0.0013506763,0.006132139],"study_design_scores_gemma":[0.00070830784,0.00051209587,0.0060998225,0.00006560228,0.000024272078,0.00006418273,0.000085400665,0.00014104691,0.9913536,0.00006241415,0.00072506064,0.00015824265],"about_ca_topic_score_codex":0.000013305315,"about_ca_topic_score_gemma":0.0000060073844,"teacher_disagreement_score":0.0059738965,"about_ca_system_score_codex":0.000055345638,"about_ca_system_score_gemma":0.000064285596,"threshold_uncertainty_score":0.6608959},"labels":[],"label_agreement":null},{"id":"W3037578553","doi":"10.1016/j.bbrc.2020.05.228","title":"Trace elements differences in the depression sensitive and resilient rat models","year":2020,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University Health Network; Public Health Ontario; University of Toronto","funders":"Peking University; Southwest University","keywords":"Selenium; Chemistry; Manganese; Cobalt; Calcium; Inductively coupled plasma mass spectrometry; Zinc; Magnesium; Sulfur; Potassium; Inductively coupled plasma; Sodium; Trace metal; Internal medicine; Environmental chemistry; Metal; Endocrinology; Biochemistry; Inorganic chemistry; Mass spectrometry; Chromatography; Medicine; Plasma","score_opus":0.1847823641261014,"score_gpt":0.3738459452562577,"score_spread":0.18906358113015628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037578553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9759233,0.00035768404,0.000025303789,0.022416292,0.000003670762,0.0002746375,0.000012995996,0.000014955718,0.0009711458],"genre_scores_gemma":[0.99792796,0.0011784853,0.00014270055,0.0006703157,0.000019042627,0.00003820451,0.000003807228,0.000004041707,0.000015462841],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844396,0.0005472279,0.00013070954,0.00029487108,0.00035947055,0.00022376352],"domain_scores_gemma":[0.99812585,0.0013356755,0.000019938396,0.0003594584,0.000033304677,0.00012574696],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020909173,0.00008052574,0.00010001059,0.000032178905,0.00029359953,0.00008060858,0.00058221666,0.00004394294,0.0000029184548],"category_scores_gemma":[0.0007106167,0.00004981344,0.00002259573,0.000422063,0.0009028165,0.00008338961,0.00051719014,0.00044563808,0.0000062907225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005204081,0.00021022312,0.00010588714,0.000011570933,0.0000012629209,0.0000017051754,0.0010757729,1.5979616e-7,0.9866006,0.008427704,0.0005443099,0.0029688014],"study_design_scores_gemma":[0.0009848663,0.00027523495,0.009773009,0.00008672669,0.000006246304,0.0000046620107,0.0033673237,0.04625972,0.9192052,0.018138373,0.001616128,0.000282533],"about_ca_topic_score_codex":0.000022545735,"about_ca_topic_score_gemma":0.000004508096,"teacher_disagreement_score":0.06739539,"about_ca_system_score_codex":0.000008542804,"about_ca_system_score_gemma":0.000019242441,"threshold_uncertainty_score":0.3326465},"labels":[],"label_agreement":null},{"id":"W3037613313","doi":"10.1016/j.bbr.2020.112721","title":"Corrigendum to “Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour” [Behav. Brain Res. 382 (2020) 112476]","year":2020,"lang":"en","type":"erratum","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Vetenskapsrådet; Hjärnfonden; Fredrik och Ingrid Thurings Stiftelse; Forskningsrådet för Arbetsliv och Socialvetenskap","keywords":"Monoamine oxidase; Monoamine oxidase A; Association (psychology); Psychology; Genotype; Neuroscience; Psychiatry; Clinical psychology; Genetics; Biology; Gene; Psychotherapist; Biochemistry; Enzyme","score_opus":0.09452604732528253,"score_gpt":0.3538190330202279,"score_spread":0.25929298569494535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037613313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89166886,0.0047040856,0.00006404174,0.085699,0.005300534,0.007473742,0.002370163,0.00023286542,0.0024867232],"genre_scores_gemma":[0.74678427,0.0015440008,0.00026393734,0.0025644228,0.0006086584,0.0006132347,0.0006727702,0.00023423108,0.2467145],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9924461,0.002042167,0.0007471454,0.0015184312,0.0021426608,0.0011034881],"domain_scores_gemma":[0.9958547,0.0016943662,0.00070972735,0.0007254512,0.00047660898,0.00053914153],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018937467,0.00061168225,0.0007845988,0.00050772825,0.0007896565,0.00043528594,0.0007514624,0.00072023994,0.00013823906],"category_scores_gemma":[0.0072774007,0.00048472633,0.00017444846,0.0012717375,0.00048487596,0.00023299594,0.0008538948,0.0022205857,0.000047191184],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049915875,0.00027214337,0.004337757,0.00013285066,0.000051538907,0.00042585848,0.002736344,0.000003220171,0.04800557,0.00037014138,0.932595,0.010570398],"study_design_scores_gemma":[0.011775688,0.0091681015,0.6408935,0.0017627628,0.00080386247,0.00036967234,0.00437213,0.0041476884,0.1143221,0.003380699,0.20405813,0.00494565],"about_ca_topic_score_codex":0.0010959068,"about_ca_topic_score_gemma":0.0006475182,"teacher_disagreement_score":0.7285369,"about_ca_system_score_codex":0.0004938293,"about_ca_system_score_gemma":0.00047409767,"threshold_uncertainty_score":0.99976045},"labels":[],"label_agreement":null},{"id":"W3038374323","doi":"10.1016/j.neubiorev.2020.05.011","title":"Corrigendum to “Evaluation of the Wistar-Kyoto rat model of depression and the role of synaptic plasticity in depression and antidepressant response” [Neurosci. Biobehav. Rev. 105 (2019) 1–23]","year":2020,"lang":"en","type":"erratum","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Depression (economics); Antidepressant; Neuroscience; Synaptic plasticity; Neuroplasticity; Psychology; Medicine; Internal medicine; Hippocampus; Economics; Receptor","score_opus":0.09670009474969199,"score_gpt":0.32555670012101473,"score_spread":0.22885660537132274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3038374323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96535474,0.020661704,0.00017289378,0.000109331326,0.0060958904,0.0069482117,0.00038109467,0.00004102629,0.00023509777],"genre_scores_gemma":[0.98879236,0.009690785,0.00007786919,0.0006083494,0.000034036406,0.0001828239,0.000005217963,0.000055538574,0.00055304536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99215484,0.0022595976,0.0015872257,0.0016017397,0.0018505813,0.00054599],"domain_scores_gemma":[0.99673474,0.00008104409,0.0016289678,0.0011484944,0.00017225559,0.00023449698],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002133898,0.0006333666,0.0013873086,0.00034334103,0.00027202783,0.00008529856,0.0016144301,0.00033813293,0.00001104272],"category_scores_gemma":[0.009593399,0.00037575368,0.00028512743,0.001426161,0.0020836238,0.00030751887,0.0012479342,0.000986995,0.0000023261882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084303453,0.000215777,0.0033058652,0.00021822115,1.6334455e-7,0.0000036557396,0.000402025,0.0001333103,0.9641022,0.000049000715,0.0056630056,0.025063721],"study_design_scores_gemma":[0.0072001712,0.0017067692,0.1491509,0.008435932,0.0011534607,0.00011753021,0.00036910837,0.18618035,0.4472957,0.0010584738,0.19492161,0.0024099932],"about_ca_topic_score_codex":0.0001083075,"about_ca_topic_score_gemma":0.000057966703,"teacher_disagreement_score":0.51680654,"about_ca_system_score_codex":0.00005435684,"about_ca_system_score_gemma":0.0004744941,"threshold_uncertainty_score":0.99986947},"labels":[],"label_agreement":null},{"id":"W3038577791","doi":"10.1097/md.0000000000021068","title":"Association between arginine catabolism and major depressive disorder","year":2020,"lang":"en","type":"article","venue":"Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Southwest University","keywords":"Medicine; Meta-analysis; Publication bias; Major depressive disorder; PsycINFO; Cochrane Library; Funnel plot; Arginine; Observational study; MEDLINE; Bioinformatics; Clinical psychology; Internal medicine; Biochemistry; Biology","score_opus":0.022395588284818087,"score_gpt":0.26421914744743435,"score_spread":0.24182355916261628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3038577791","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8854115,0.0007014246,0.00040957276,0.1101148,0.00015212361,0.00020826394,0.000025623694,0.00011342707,0.0028632805],"genre_scores_gemma":[0.9917654,0.00013346483,0.00002205523,0.007012109,0.0005069386,0.000006956502,0.000010302203,0.000012341299,0.00053048163],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991007,0.000053711803,0.00014105874,0.00027187087,0.0002511039,0.00018154825],"domain_scores_gemma":[0.99939334,0.00027820983,0.00008538898,0.000088187706,0.000016460135,0.00013841905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000070648246,0.000099448924,0.0001851295,0.000034808276,0.000083682615,0.000011081188,0.00011485971,0.000048918828,0.00021026394],"category_scores_gemma":[0.002025285,0.000076842494,0.000015261585,0.0002284625,0.00008597256,0.000078511475,0.000050917246,0.00013908459,0.00004511465],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009477851,0.0000850716,0.58356756,0.00016402134,0.00007422023,0.000059560407,0.011022043,0.000008220264,0.21807572,0.00198928,0.11941012,0.06544939],"study_design_scores_gemma":[0.008531745,0.00035627655,0.6869752,0.000064797045,0.00012565864,0.0000050141552,0.00063447666,0.00037224774,0.05324052,0.0015200254,0.24774204,0.00043202846],"about_ca_topic_score_codex":0.000046288966,"about_ca_topic_score_gemma":0.000006749318,"teacher_disagreement_score":0.1648352,"about_ca_system_score_codex":0.000010624364,"about_ca_system_score_gemma":0.000010201359,"threshold_uncertainty_score":0.3133546},"labels":[],"label_agreement":null},{"id":"W3040358866","doi":"10.1016/j.nutres.2020.06.019","title":"Dietary supplementation with Lactobacillus rhamnosus JB-1 restores brain neurochemical balance and mitigates the progression of mood disorder in a rat model of chronic unpredictable mild stress","year":2020,"lang":"en","type":"article","venue":"Nutrition Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Narodowe Centrum Nauki","keywords":"Glutamine; Neurochemical; Glutamate receptor; Endocrinology; Internal medicine; Lactobacillus rhamnosus; Creatine; In vivo; Glutamine synthetase; Biology; Chemistry; Medicine; Biochemistry; Lactobacillus; Fermentation; Amino acid","score_opus":0.06210566766677707,"score_gpt":0.34129172696528864,"score_spread":0.2791860592985116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3040358866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9858096,0.00061512255,0.000042129424,0.012351126,0.000010402839,0.00085988967,0.00015776364,0.000019290723,0.00013466638],"genre_scores_gemma":[0.9987821,0.0007185503,0.00014381032,0.00012433181,0.000026495642,0.00013650261,0.00003621997,0.000014584097,0.00001743011],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803716,0.00032064584,0.00024950254,0.00037401,0.0007025628,0.00031613183],"domain_scores_gemma":[0.99905163,0.00053148123,0.00007117434,0.00017208482,0.00008943624,0.000084186475],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021321801,0.00011294598,0.00016893345,0.000107402346,0.000106343694,0.000029128472,0.00025510453,0.000058161113,0.00002433563],"category_scores_gemma":[0.00039365058,0.0000807711,0.000027352286,0.000678604,0.0006254009,0.00017477728,0.00012391295,0.00033661487,7.331929e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010039697,0.0005702741,0.01169814,0.00072001887,0.000003560155,0.0000045919874,0.00085072656,0.0006310207,0.98175454,0.0002447888,0.0017071773,0.0008112056],"study_design_scores_gemma":[0.004119122,0.0010844856,0.0025270795,0.000379124,0.0000033446524,0.0000022650065,0.001207041,0.073158845,0.9167409,0.0005235592,0.00013906237,0.000115178],"about_ca_topic_score_codex":0.00005204204,"about_ca_topic_score_gemma":0.00016935031,"teacher_disagreement_score":0.072527826,"about_ca_system_score_codex":0.000023006,"about_ca_system_score_gemma":0.00009288374,"threshold_uncertainty_score":0.32937497},"labels":[],"label_agreement":null},{"id":"W3040622222","doi":"10.1186/s13223-020-00457-7","title":"Th17/Treg imbalance is associated with reduced indoleamine 2,3 dioxygenase activity in childhood allergic asthma","year":2020,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Major Science and Technology Projects of China; National Natural Science Foundation of China","keywords":"Indoleamine 2,3-dioxygenase; Medicine; Immunology; Asthma; Pathogenesis; Eosinophil; Allergy; Sputum; Treg cell; Regulatory T cell; IL-2 receptor; Immune system; T cell; Biology","score_opus":0.025801043100944155,"score_gpt":0.274376096194691,"score_spread":0.24857505309374683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3040622222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905165,0.00038319296,0.000026725615,0.0072926665,0.00015775212,0.00025868605,0.000019635578,0.00013535951,0.0012095093],"genre_scores_gemma":[0.9917695,0.0013676056,0.000033066335,0.006422548,0.000084308136,0.000022268021,0.000010283219,0.000039936993,0.00025046756],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99676865,0.00067098986,0.0005841629,0.0011015683,0.00022976071,0.0006448776],"domain_scores_gemma":[0.9982247,0.0008570329,0.0002992639,0.00036432507,0.00003788609,0.00021682733],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023357703,0.0003618364,0.0007112705,0.00008072388,0.00014299736,0.000042876378,0.00045992632,0.00041328272,0.00021070866],"category_scores_gemma":[0.0016401296,0.0003094416,0.00014944225,0.00060117536,0.00065831764,0.00021256796,0.000259292,0.0009770299,0.00007226611],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015054655,0.016766673,0.016224941,0.00006442713,0.0026378925,0.0028046633,0.008774583,0.00013956965,0.6624582,0.00564183,0.004981318,0.2644513],"study_design_scores_gemma":[0.008513734,0.0025861387,0.9487361,0.00006578849,0.0000044534854,0.00004493724,0.00025047382,0.00054110715,0.03175843,0.00026404148,0.006623205,0.0006116223],"about_ca_topic_score_codex":0.000039572424,"about_ca_topic_score_gemma":0.00025654744,"teacher_disagreement_score":0.93251115,"about_ca_system_score_codex":0.000026743408,"about_ca_system_score_gemma":0.00011669023,"threshold_uncertainty_score":0.99993575},"labels":[],"label_agreement":null},{"id":"W3043043206","doi":"10.1113/ep088605","title":"Combination of quercetin and exercise training attenuates depression in rats with 1,2‐dimethylhydrazine‐induced colorectal cancer: Possible involvement of inflammation and BDNF signalling","year":2020,"lang":"en","type":"article","venue":"Experimental Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acadia University","funders":"","keywords":"1,2-Dimethylhydrazine; Colorectal cancer; Medicine; Dimethylhydrazine; Internal medicine; Depression (economics); Quercetin; Cancer; Mindfulness; Inflammation; Endocrinology; Oncology; Clinical psychology; Chemistry; Antioxidant; Biochemistry","score_opus":0.034642155110120317,"score_gpt":0.2776015842052685,"score_spread":0.24295942909514817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043043206","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99910605,0.00040215504,0.000004642279,0.00009342145,0.000022424418,0.00030145384,0.0000031145423,0.000013756712,0.00005297505],"genre_scores_gemma":[0.9997238,0.00006808587,0.00008306326,0.000058173373,0.000011487816,0.000039650768,0.000005349983,0.000009310596,0.0000011092775],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992209,0.00008550799,0.00020653867,0.0002661803,0.00009928481,0.0001215572],"domain_scores_gemma":[0.99968016,0.0000778411,0.00014483025,0.000040398678,0.000014678778,0.00004211646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000048252838,0.00010752983,0.00023048041,0.000060544065,0.000039419585,0.0000064528267,0.00006238516,0.00004496841,0.000013201502],"category_scores_gemma":[0.000026457226,0.00009340163,0.000014572908,0.00014898338,0.00014318142,0.00013170434,0.00006084476,0.00006997076,3.3411e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040734853,0.00007246495,0.0009276948,0.00004749075,0.0000033697766,9.498372e-7,0.009901912,0.00016843346,0.9863109,0.0000913459,0.000001785586,0.0020662753],"study_design_scores_gemma":[0.0013560543,0.0005398448,0.022960357,0.0001002142,0.0000028231077,5.283753e-7,0.0026729773,0.003379008,0.9687979,0.000098404154,6.9267014e-7,0.000091147915],"about_ca_topic_score_codex":0.00008959256,"about_ca_topic_score_gemma":0.000010344841,"teacher_disagreement_score":0.022032661,"about_ca_system_score_codex":0.000014113737,"about_ca_system_score_gemma":0.00002220851,"threshold_uncertainty_score":0.38088077},"labels":[],"label_agreement":null},{"id":"W3043409646","doi":"10.1016/j.biopsych.2020.05.028","title":"Meta-analysis of the Glial Marker TSPO in Psychosis Revisited: Reconciling Inconclusive Findings of Patient–Control Differences","year":2020,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of Neurological Disorders and Stroke; Medical Research Council; National Institute of Mental Health; Vetenskapsrådet; National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology; Lundbeckfonden; King’s College London; Academy of Finland; Svenska Sällskapet för Medicinsk Forskning; Ohio Department of Health; Wellcome Trust; Roche; AstraZeneca Canada; King's College London; Eli Lilly and Company","keywords":"Psychosis; Psychology; Neuroscience; Meta-analysis; Psychiatry; Medicine; Internal medicine","score_opus":0.13022783600873536,"score_gpt":0.3311643023347083,"score_spread":0.20093646632597292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043409646","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010998704,0.9854949,0.000006378387,0.00044759279,0.00056361075,0.0011282812,0.0008549335,0.000025379679,0.00048018768],"genre_scores_gemma":[0.08911896,0.9092016,0.00012067078,0.0013383166,0.00006954644,0.00008754667,0.000016560401,0.00002232657,0.000024425304],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9949736,0.0016059753,0.0016739502,0.00101707,0.0003947603,0.00033464318],"domain_scores_gemma":[0.9966254,0.0013338353,0.0013270221,0.0005877976,0.000038655693,0.00008723669],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036858668,0.00053822895,0.0047270814,0.00036157217,0.00007522819,0.000021447682,0.0012670042,0.0005241173,0.0007073563],"category_scores_gemma":[0.0010872628,0.00026262234,0.0049835937,0.0030274636,0.0003690711,0.000043570522,0.00025193876,0.0006125876,0.000012225987],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012959578,0.0041384674,0.12918589,0.01935303,0.20656793,0.000037189955,0.0014697778,0.000031911433,0.00066498463,0.012799524,0.0036070053,0.62084836],"study_design_scores_gemma":[0.002811549,0.0018410181,0.02684733,0.0045218943,0.36551383,0.000016694834,0.00046965858,0.000106523425,0.00010693026,0.0051487084,0.5893057,0.003310193],"about_ca_topic_score_codex":0.000022601771,"about_ca_topic_score_gemma":0.000029697745,"teacher_disagreement_score":0.61753815,"about_ca_system_score_codex":0.000036536094,"about_ca_system_score_gemma":0.0001267865,"threshold_uncertainty_score":0.9999826},"labels":[],"label_agreement":null},{"id":"W3044274463","doi":"10.31487/j.nnb.2020.03.03","title":"Metabolomics of Rat Brain After Treatment with Phenelzine: High-Resolution Mass Spectrometric Demonstration of Increased Brain Levels of N-Acetyl Amino Acids","year":2020,"lang":"en","type":"article","venue":"Neurology and Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta; Lincoln Memorial University","keywords":"Phenelzine; Chemistry; Neurochemical; Metabolite; Neurochemistry; Amino acid; Monoamine oxidase inhibitor; Monoamine oxidase; Pharmacology; Metabolomics; Biochemistry; Internal medicine; Neurology; Medicine; Chromatography; Enzyme; Neuroscience; Psychology","score_opus":0.019244211105150344,"score_gpt":0.22519763874896728,"score_spread":0.20595342764381694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044274463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99421227,0.00012526488,0.0006021778,0.0044162385,0.00012299792,0.00031066794,0.00011671859,0.000029141956,0.00006451142],"genre_scores_gemma":[0.9957805,0.00013597647,0.0002139635,0.0037848817,0.00002820863,0.000015418807,0.000009591041,0.000017770986,0.000013675437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797744,0.00068771373,0.00041917272,0.00054748595,0.000090786474,0.00027739047],"domain_scores_gemma":[0.99841446,0.000931271,0.000320906,0.00021427448,0.00003708416,0.00008202756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000097572156,0.00023561266,0.0005699904,0.00023224598,0.000040439838,0.0000038821645,0.0001553987,0.00019029746,0.000055926357],"category_scores_gemma":[0.00033102458,0.00018895874,0.00007837698,0.0006020324,0.000750207,0.00008262266,0.00005158676,0.00017351224,0.0000021333396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024995022,0.00014075426,0.009970449,0.000034569384,0.000020704061,0.000019802974,0.00009421659,0.00006422643,0.985215,0.0013241161,0.000033146847,0.0005834998],"study_design_scores_gemma":[0.0028841104,0.01147542,0.1213661,0.0000032161472,0.000045991044,0.000059488208,0.0000104770525,0.00025883794,0.8633012,0.00018844898,0.00026286638,0.00014380287],"about_ca_topic_score_codex":0.00001956191,"about_ca_topic_score_gemma":0.00001800722,"teacher_disagreement_score":0.12191377,"about_ca_system_score_codex":0.0000054698007,"about_ca_system_score_gemma":0.00006236479,"threshold_uncertainty_score":0.7705514},"labels":[],"label_agreement":null},{"id":"W3044950861","doi":"10.1002/mds.28202","title":"Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease","year":2020,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; College of Engineering, Michigan State University; National Institutes of Health; U.S. Department of Veterans Affairs; H. Lundbeck A/S; Weston Brain Institute; Michigan State University; Biogen; National Institute of Mental Health; Pfizer; Alzheimer's Association; Michael J. Fox Foundation for Parkinson's Research; Bristol-Myers Squibb; Axial Biotherapeutics; U.S. Department of Defense","keywords":"Quinolinic acid; Kynurenine; Kynurenine pathway; Kynurenic acid; Substantia nigra; Cerebrospinal fluid; Parkinson's disease; Metabolite; Internal medicine; Medicine; Central nervous system disease; Neuroprotection; Endocrinology; Pathology; Disease; Chemistry; Tryptophan; Biochemistry; Glutamate receptor","score_opus":0.01398866498633532,"score_gpt":0.2178828725245477,"score_spread":0.20389420753821236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044950861","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98901975,0.0005524835,0.00006944231,0.009183867,0.000051780396,0.0004468367,0.00006085602,0.00012842515,0.00048653185],"genre_scores_gemma":[0.9745408,0.00023189641,0.000019987036,0.02500107,0.000016692253,0.00007760268,0.000011845749,0.00003064608,0.000069411435],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981797,0.00018294522,0.00021723768,0.000663285,0.00028789623,0.0004689471],"domain_scores_gemma":[0.999317,0.000121711026,0.00011802125,0.00017237551,0.000011525209,0.0002594059],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000076953576,0.00025810735,0.00028234645,0.000111616246,0.00010364561,0.000062112325,0.00021391409,0.00005728627,0.000070521084],"category_scores_gemma":[0.00049431797,0.00022400336,0.00005783006,0.0005673015,0.00023280563,0.00017528585,0.00008995808,0.00016993136,0.0000093410235],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049945555,0.0007534329,0.9682251,0.00007096601,0.000035879704,0.00024425844,0.0018636123,0.0002185294,0.016974399,0.004026803,0.0010636402,0.006023903],"study_design_scores_gemma":[0.004190075,0.00029140594,0.97491866,0.000045461704,0.000023354678,1.9241875e-7,0.0011204735,0.0012558955,0.0036892972,0.011007698,0.0029179985,0.0005394579],"about_ca_topic_score_codex":0.00001867062,"about_ca_topic_score_gemma":0.00025865642,"teacher_disagreement_score":0.015817203,"about_ca_system_score_codex":0.000026533555,"about_ca_system_score_gemma":0.00003233342,"threshold_uncertainty_score":0.9134592},"labels":[],"label_agreement":null},{"id":"W3046211596","doi":"10.1021/acs.chemrestox.0c00191","title":"Investigation of Clozapine and Olanzapine Reactive Metabolite Formation and Protein Binding by Liquid Chromatography-Tandem Mass Spectrometry","year":2020,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Metabolite; Glutathione; Microsome; Drug metabolism; Biochemistry; Metabolism; Enzyme","score_opus":0.08438584768638768,"score_gpt":0.33261789969117633,"score_spread":0.24823205200478865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046211596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99484724,0.00048640213,0.00009159172,0.003773391,0.000009320901,0.00046336072,0.000016957682,0.000024112507,0.0002876351],"genre_scores_gemma":[0.998881,0.0003447914,0.00042041732,0.00025172796,0.000025613475,0.000049416685,0.000010206118,0.000010188759,0.000006660551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844325,0.0002867905,0.0002556474,0.00036701,0.00029521048,0.0003520744],"domain_scores_gemma":[0.99918276,0.00041305734,0.000077830686,0.000090241876,0.00003697383,0.00019913922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045157628,0.00010288163,0.0002273812,0.00028738033,0.000050559163,0.000022829197,0.0001489687,0.0001401746,0.0000177334],"category_scores_gemma":[0.0020137301,0.00009734834,0.000021991744,0.0011463606,0.00068555196,0.00022442822,0.00013266876,0.0004376204,0.000002903672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023696214,0.000022764978,0.00022672235,0.000109914174,0.0000033540728,0.0000046457244,0.00031362762,6.0403245e-8,0.9970226,0.0015430013,0.00011531459,0.00040102427],"study_design_scores_gemma":[0.00094365684,0.0004164773,0.0004023605,0.000028314907,0.0000015153612,0.000005856326,0.00014834254,0.0002979552,0.99526507,0.0020654807,0.00034131456,0.00008368848],"about_ca_topic_score_codex":0.0000055152627,"about_ca_topic_score_gemma":9.0321953e-7,"teacher_disagreement_score":0.0040337495,"about_ca_system_score_codex":0.00004127485,"about_ca_system_score_gemma":0.000038518232,"threshold_uncertainty_score":0.396975},"labels":[],"label_agreement":null},{"id":"W3046273327","doi":"10.1007/s11033-020-05696-w","title":"Minocycline attenuates depressive-like behaviors in mice treated with the low dose of intracerebroventricular streptozotocin; the role of mitochondrial function and neuroinflammation","year":2020,"lang":"en","type":"article","venue":"Molecular Biology Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Zanjan University of Medical Sciences","keywords":"Neuroinflammation; Minocycline; Streptozotocin; Pharmacology; Medicine; Mitochondrion; Chemistry; Internal medicine; Endocrinology; Diabetes mellitus; Inflammation; Biochemistry; Antibiotics","score_opus":0.0060600851295368975,"score_gpt":0.21900786251381477,"score_spread":0.21294777738427786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046273327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99814373,0.0002160325,0.0002822725,0.00061507564,0.000054981796,0.0006441461,0.000004885577,0.00001611871,0.000022770868],"genre_scores_gemma":[0.9996732,0.000009922787,0.000029505938,0.00020809326,0.00001653429,0.000034026336,0.000012933643,0.000010809554,0.000005011075],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99881375,0.0002290662,0.00033476407,0.00035838506,0.000121190445,0.00014283074],"domain_scores_gemma":[0.9992103,0.00009907506,0.000396631,0.00022108378,0.00003821042,0.000034712637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000069405076,0.0001313633,0.00018544102,0.000044445427,0.00004690744,0.000010239882,0.000108803906,0.00007970224,0.000007652114],"category_scores_gemma":[0.00023315942,0.00007462153,0.000053070395,0.00028960904,0.00028069376,0.000042729385,0.000055768774,0.00012995885,4.5964725e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019089544,0.00005558504,0.037002392,0.000009148104,0.000010662591,0.00010142743,0.00013300356,0.00022755185,0.9612302,0.000035211728,0.000010686904,0.0009932063],"study_design_scores_gemma":[0.0006262011,0.00028341438,0.0278511,0.000011696682,0.000042252963,0.0000829718,0.00012230454,0.00034180988,0.9702922,0.00017948674,0.00008218238,0.00008437308],"about_ca_topic_score_codex":0.00007610751,"about_ca_topic_score_gemma":0.000023823424,"teacher_disagreement_score":0.009151293,"about_ca_system_score_codex":0.0000042988336,"about_ca_system_score_gemma":0.000024205629,"threshold_uncertainty_score":0.30429778},"labels":[],"label_agreement":null},{"id":"W3047403558","doi":"10.1007/s12035-020-02047-5","title":"Lowered Antioxidant Defenses and Increased Oxidative Toxicity Are Hallmarks of Deficit Schizophrenia: a Nomothetic Network Psychiatry Approach","year":2020,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Asahi Glass Foundation","keywords":"Oxidative stress; Paraoxonase; Schizophrenia (object-oriented programming); PON1; Malondialdehyde; Psychology; Internal medicine; Neuroinflammation; Cognitive deficit; Medicine; Psychiatry; Chemistry; Inflammation; Biochemistry; Cognition; Genotype","score_opus":0.015309142492274393,"score_gpt":0.21510766432272369,"score_spread":0.1997985218304493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047403558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99315184,0.00030724314,0.004136168,0.001079816,0.0001242037,0.00038501536,0.000045521574,0.000090141264,0.0006800765],"genre_scores_gemma":[0.99110895,0.00003140269,0.0020275733,0.0067337058,0.000039098308,0.000012746687,0.0000065110503,0.0000362846,0.0000037242664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978052,0.000507697,0.0003471512,0.00080169854,0.00012027968,0.00041799346],"domain_scores_gemma":[0.9990898,0.00015569277,0.00025402784,0.0003032331,0.00003076876,0.00016647161],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000085894564,0.0002871203,0.00047712628,0.00007342958,0.000105576044,0.000023465007,0.00033921,0.0002137597,0.000020312184],"category_scores_gemma":[0.00050385675,0.00026686405,0.00014161985,0.00043876018,0.00045520146,0.000048426293,0.0002014656,0.00038706523,0.000009060215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000500642,0.00021649929,0.0021923326,0.00008632435,0.000021849126,0.000043482898,0.000073557916,0.00028288167,0.9892279,0.0070086075,0.00020782794,0.00013810187],"study_design_scores_gemma":[0.008331948,0.0027198065,0.079101264,0.00014613329,0.00015167583,0.00044456168,0.00033728653,0.003926954,0.8947911,0.007822452,0.00056890567,0.0016578976],"about_ca_topic_score_codex":0.000009807689,"about_ca_topic_score_gemma":0.00000787544,"teacher_disagreement_score":0.09443678,"about_ca_system_score_codex":0.000006138626,"about_ca_system_score_gemma":0.000057571455,"threshold_uncertainty_score":0.99997836},"labels":[],"label_agreement":null},{"id":"W3047717333","doi":"10.1038/s41598-020-69968-y","title":"Increased persistence of avoidance behaviour and social deficits with L.rhamnosus JB-1 or selective serotonin reuptake inhibitor treatment following social defeat","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"W. Garfield Weston Foundation","keywords":"Sertraline; Serotonin reuptake inhibitor; Social defeat; Reuptake inhibitor; Psychology; Serotonin; Lactobacillus rhamnosus; Fluoxetine; Pharmacology; Medicine; Psychiatry; Internal medicine; Probiotic; Anxiety; Antidepressant; Biology; Receptor","score_opus":0.04270708674649225,"score_gpt":0.25699958864698585,"score_spread":0.2142925019004936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047717333","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759877,0.00005340295,0.000022072074,0.0004886915,0.00047564282,0.0006920068,0.000019545434,0.00009753787,0.0005523614],"genre_scores_gemma":[0.99891424,0.0000021151584,0.0002175553,0.00014850161,0.000065339984,0.000053885153,0.000009507035,0.000026722322,0.00056212797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971615,0.00013395489,0.00041398295,0.0011896467,0.0006789906,0.000421897],"domain_scores_gemma":[0.9990646,0.00008365979,0.0003775342,0.0002269912,0.00009668089,0.00015048224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027359716,0.00026433752,0.0003830901,0.000097759395,0.000939477,0.00020652656,0.00015085077,0.00009269622,0.000026459575],"category_scores_gemma":[0.00032747202,0.00020256347,0.00016869791,0.0008989978,0.00056453905,0.00025883518,0.00007668239,0.00013541296,0.000003914422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00085134484,0.0005218954,0.035733826,0.000114437666,0.000057917685,0.002114933,0.029994372,0.000014928459,0.9260242,0.000096863856,0.0021154932,0.0023597789],"study_design_scores_gemma":[0.0020281866,0.0009094455,0.01787187,0.00007043738,0.00012427942,0.00026159425,0.0047541023,0.00009786254,0.97165203,0.00015865568,0.0014924359,0.0005791036],"about_ca_topic_score_codex":0.000045117107,"about_ca_topic_score_gemma":0.00011152455,"teacher_disagreement_score":0.04562782,"about_ca_system_score_codex":0.00010258115,"about_ca_system_score_gemma":0.00041310934,"threshold_uncertainty_score":0.82602984},"labels":[],"label_agreement":null},{"id":"W3048028461","doi":"10.2174/1570159x18666200729103529","title":"Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry","year":2020,"lang":"en","type":"review","venue":"Current Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Oxidative stress; Tetrahydrobiopterin; Nitric oxide; Monoaminergic; Pharmacology; Inflammation; Nitric oxide synthase; Medicine; Biochemistry; Chemistry; Endocrinology; Internal medicine; Serotonin","score_opus":0.0882246047256004,"score_gpt":0.3684870279082048,"score_spread":0.2802624231826044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048028461","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00046817772,0.9658199,0.000028636421,0.00046719873,0.029244166,0.0018609617,0.001182967,0.00053565664,0.00039233745],"genre_scores_gemma":[0.00013983977,0.9906949,0.00004438717,0.005627845,0.0028254976,0.00025790063,0.00006383498,0.00026824322,0.00007759527],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9928554,0.0021711574,0.0010863254,0.0024867256,0.00041085292,0.0009895115],"domain_scores_gemma":[0.99684983,0.0011005433,0.00048685746,0.00072754896,0.000026553531,0.0008086899],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00008481516,0.0011958865,0.0024895219,0.00046670574,0.00023599491,0.00013039842,0.0020761671,0.0003039697,0.0010813393],"category_scores_gemma":[0.00070886646,0.0010858864,0.0009200218,0.0014667487,0.00019766319,0.00012356647,0.00096114125,0.0025018381,0.0063678105],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036641108,0.00026199178,1.554569e-7,0.0016210829,0.000032804262,0.00041574138,0.00005920248,0.0000026782088,0.00865458,0.00016537127,0.017761676,0.9709881],"study_design_scores_gemma":[0.0005892578,0.00011143834,0.000005936346,0.00046392917,0.00032153833,0.000055383338,0.000002034019,0.00001781699,0.0008907655,0.000031321306,0.99664336,0.00086722],"about_ca_topic_score_codex":0.0000037470118,"about_ca_topic_score_gemma":8.428991e-7,"teacher_disagreement_score":0.97888166,"about_ca_system_score_codex":0.0000630641,"about_ca_system_score_gemma":0.00043772647,"threshold_uncertainty_score":0.9998318},"labels":[],"label_agreement":null},{"id":"W3048903427","doi":"10.3389/fpsyt.2020.00781","title":"Microglial Dysregulation and Suicidality: A Stress-Diathesis Perspective","year":2020,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Waypoint Centre for Mental Health Care; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Centre for Addiction and Mental Health","keywords":"Quinolinic acid; Psychology; Kynurenine pathway; Microglia; Neuroscience; Monoaminergic; Medicine; Internal medicine; Inflammation; Biology; Serotonin; Kynurenine","score_opus":0.026413806007057807,"score_gpt":0.3029695164943146,"score_spread":0.2765557104872568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048903427","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000058457306,0.99118716,0.0001590759,0.0006517979,0.005500884,0.00077793427,0.0002557703,0.00009390391,0.0013149922],"genre_scores_gemma":[0.00006928306,0.99610895,0.0027481455,0.00036159556,0.00042534343,0.000057621368,0.000014476333,0.00007332329,0.0001412456],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975005,0.0003577155,0.00048125387,0.001042387,0.00024522096,0.00037295878],"domain_scores_gemma":[0.99913764,0.00009458891,0.00028565628,0.00033522365,0.000014415403,0.00013248686],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010137609,0.00047215947,0.0011978191,0.0003837131,0.00010514065,0.00010001894,0.00041192537,0.000357866,0.000020447891],"category_scores_gemma":[0.00024616372,0.0004457286,0.0003211103,0.00070768385,0.00021534214,0.00013746203,0.00010729747,0.0005429354,0.000021986665],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041543582,0.00017705165,0.0005448791,0.00483943,0.00008576919,0.000030431682,0.0007963863,5.4790445e-7,0.00000393168,0.0041765594,0.018137023,0.97116643],"study_design_scores_gemma":[0.0009204421,0.00011759709,0.000114747316,0.0036024456,0.00029007337,0.000051486808,0.0024880923,0.00005650114,0.000016158168,0.015302796,0.97597665,0.0010630228],"about_ca_topic_score_codex":0.000028670453,"about_ca_topic_score_gemma":0.000031264848,"teacher_disagreement_score":0.97010344,"about_ca_system_score_codex":0.00018781489,"about_ca_system_score_gemma":0.0003389345,"threshold_uncertainty_score":0.99979943},"labels":[],"label_agreement":null},{"id":"W3049179147","doi":"10.1101/2020.08.11.20172940","title":"Neuroinflammation, Depressive Affect, and Amyloid Burden in Alzheimer’s Disease: Insights from the Kynurenine Pathway","year":2020,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; University of California, San Diego; Danone Nutricia Research; National Institutes of Health; Iowa State University; Canadian Institutes of Health Research; Danone; University of Southern California; Northern California Institute for Research and Education; Alzheimer's Drug Discovery Foundation; National Institute on Aging; Alzheimer's Association; Foundation for the National Institutes of Health; U.S. Department of Defense","keywords":"Kynurenine; Kynurenine pathway; Subclinical infection; Psychology; Neuroinflammation; Internal medicine; Atrophy; Disease; Neuroscience; Medicine; Oncology; Biology; Tryptophan","score_opus":0.03584007331381307,"score_gpt":0.2586441484872286,"score_spread":0.22280407517341555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3049179147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98495567,0.0050745993,0.000058778878,0.0077028945,0.00050562713,0.0009631104,0.00014074102,0.00015554532,0.00044302395],"genre_scores_gemma":[0.99777347,0.00047324994,0.000028899129,0.0010324408,0.0004189841,0.0001325185,0.000055787128,0.000051907882,0.00003274525],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9971675,0.00059027696,0.00037559276,0.001144581,0.00043881647,0.00028322113],"domain_scores_gemma":[0.99788237,0.00086777785,0.00024542163,0.00074868806,0.000026449163,0.00022929668],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007585742,0.00041364742,0.00036964717,0.000091468675,0.00015389995,0.00020421641,0.000868232,0.00015118769,0.000060905397],"category_scores_gemma":[0.0013966726,0.0003008188,0.00011396036,0.00027542852,0.00025450802,0.00012437651,0.0009820943,0.000823416,0.000057261623],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007587947,0.00029025413,0.07018902,0.0002964083,0.0001725244,0.002473296,0.01759174,0.003391754,0.8763748,0.0061834548,0.00411221,0.018165762],"study_design_scores_gemma":[0.0014612959,0.000047659265,0.8504469,0.00032573825,0.00010503384,0.000005050894,0.00010828628,0.005454322,0.10429861,0.027934399,0.008928735,0.000883979],"about_ca_topic_score_codex":0.00014385812,"about_ca_topic_score_gemma":0.00017250498,"teacher_disagreement_score":0.7802579,"about_ca_system_score_codex":0.000015446312,"about_ca_system_score_gemma":0.00013357738,"threshold_uncertainty_score":0.9999444},"labels":[],"label_agreement":null},{"id":"W3049338676","doi":"10.1097/jcp.0000000000001253","title":"Anti-inflammatory Combination Therapy for the Treatment of Schizophrenia","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Scale for the Assessment of Negative Symptoms; Schizoaffective disorder; Brief Psychiatric Rating Scale; Schizophrenia (object-oriented programming); Randomized controlled trial; Rating scale; Medicine; Placebo; Internal medicine; Negative symptom; Hamilton Rating Scale for Depression; Depression (economics); Psychiatry; Positive and Negative Syndrome Scale; Antipsychotic; Major depressive disorder; Psychology; Psychosis; Cognition","score_opus":0.11669461860842564,"score_gpt":0.43514438441576786,"score_spread":0.3184497658073422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3049338676","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97820604,0.00064360816,0.00041898346,0.017702037,0.002470926,0.00043144342,0.000006265221,0.000010572984,0.00011012359],"genre_scores_gemma":[0.9846998,0.007857739,0.00014052357,0.006370258,0.00088159955,0.000008511889,2.0674418e-7,0.000012352193,0.000029039475],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982009,0.00029909698,0.0010144553,0.00016726114,0.0001781315,0.00014016694],"domain_scores_gemma":[0.9955629,0.0032384964,0.0008711948,0.00009644302,0.00010581674,0.00012511361],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042167827,0.00010714066,0.00043532258,0.000045698132,0.00006527995,0.000010073826,0.0003499112,0.000087529086,0.00014329498],"category_scores_gemma":[0.0005540649,0.00006257274,0.00045180117,0.00014086289,0.00024394943,0.00007637029,0.000008358636,0.00019208532,0.00000960354],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03695511,0.005012747,0.003704673,0.000035926394,0.0003718248,0.000040865823,0.00080372667,0.00022288001,0.53503895,0.0018570902,0.031272292,0.38468394],"study_design_scores_gemma":[0.120470405,0.025837298,0.06781906,0.00001935491,0.0001805427,0.000034625147,0.00014445772,0.0028796215,0.23752522,0.003910737,0.54086,0.00031867318],"about_ca_topic_score_codex":2.4108076e-7,"about_ca_topic_score_gemma":1.9883589e-7,"teacher_disagreement_score":0.5095877,"about_ca_system_score_codex":0.000009375713,"about_ca_system_score_gemma":0.000107255175,"threshold_uncertainty_score":0.2551642},"labels":[],"label_agreement":null},{"id":"W3081365535","doi":"10.3389/fncel.2020.00274","title":"The Inflamed Brain in Schizophrenia: The Convergence of Genetic and Environmental Risk Factors That Lead to Uncontrolled Neuroinflammation","year":2020,"lang":"en","type":"review","venue":"Frontiers in Cellular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":206,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; University of British Columbia; Université Laval","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression; National Science Foundation","keywords":"Neuroinflammation; Schizophrenia (object-oriented programming); Synaptic pruning; Neuroscience; Immune system; Microglia; Disease; Inflammation; Medicine; Psychology; Biology; Immunology; Psychiatry; Pathology","score_opus":0.022796684673856534,"score_gpt":0.2384250504165785,"score_spread":0.21562836574272196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081365535","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.107862726,0.88191307,0.0019319506,0.00061717595,0.0029587997,0.004511577,0.00011053983,0.00005067737,0.00004350967],"genre_scores_gemma":[0.12069316,0.87877715,0.000077410616,0.0002090483,0.000026197495,0.000087694956,0.000002899264,0.00004603713,0.000080432124],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9952438,0.0014299254,0.00088070874,0.0011489304,0.0007078693,0.0005887708],"domain_scores_gemma":[0.9972443,0.0012647349,0.0006512543,0.0006783488,0.00000531904,0.00015602772],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000536429,0.00052781025,0.0010187104,0.0003178835,0.0003537178,0.00015531474,0.0017286824,0.0001509652,0.0000032574035],"category_scores_gemma":[0.002633959,0.00033100744,0.00023407888,0.0013329722,0.0011783084,0.00018009028,0.00043463553,0.0008307729,0.0000069577072],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027675673,0.00016920382,0.009419139,0.0012354171,0.000016139895,0.00028087452,0.0021080717,0.0011894739,0.032237224,0.00012742529,0.0008460492,0.9520942],"study_design_scores_gemma":[0.0033717742,0.0006527604,0.016321497,0.0015078645,0.00018866429,0.000054746335,0.0012719657,0.03660349,0.0115609225,0.00071338675,0.9256832,0.0020697175],"about_ca_topic_score_codex":0.000027983098,"about_ca_topic_score_gemma":0.000031407224,"teacher_disagreement_score":0.9500245,"about_ca_system_score_codex":0.00009279899,"about_ca_system_score_gemma":0.00016485494,"threshold_uncertainty_score":0.99991417},"labels":[],"label_agreement":null},{"id":"W3081448604","doi":"10.3389/fpsyt.2020.00852","title":"Maternal Immune Activation and the Development of Dopaminergic Neurotransmission of the Offspring: Relevance for Schizophrenia and Other Psychoses","year":2020,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Offspring; Schizophrenia (object-oriented programming); Dopaminergic; Neuroscience; Immune system; Psychosis; Psychology; Pregnancy; Medicine; Dopamine; Bioinformatics; Psychiatry; Immunology; Biology; Genetics","score_opus":0.024439310532860598,"score_gpt":0.280293282869995,"score_spread":0.2558539723371344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081448604","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0036973055,0.99022305,0.0018438293,0.00037458507,0.0020299968,0.0014707665,0.000016074804,0.000016043688,0.00032833585],"genre_scores_gemma":[0.004593386,0.975965,0.01874789,0.00016338174,0.0000700179,0.00012508768,9.760419e-7,0.00009284863,0.00024140769],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99869025,0.00014524229,0.0005460836,0.00033296293,0.00015438534,0.00013107777],"domain_scores_gemma":[0.99913824,0.00011314498,0.00048472095,0.00023000436,0.000006926837,0.000026949156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013758619,0.00021837579,0.00061827136,0.00009837908,0.00007540025,0.0000148843055,0.00037226707,0.00009398832,0.0000034205157],"category_scores_gemma":[0.000109472094,0.00012067543,0.00013588008,0.0002848895,0.00026735937,0.00003751616,0.000059315058,0.00019098209,2.5844324e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006091727,0.000070342845,0.00046762932,0.009558595,0.000043308224,1.2900304e-7,0.00036998565,0.0000011448332,0.00062043377,0.002279629,0.0009981535,0.9849815],"study_design_scores_gemma":[0.003472237,0.000046484536,0.0017632075,0.010042483,0.0000831295,0.0000073980805,0.00008892409,0.00008272481,0.0020022874,0.0023101107,0.97979033,0.00031068712],"about_ca_topic_score_codex":0.000003187283,"about_ca_topic_score_gemma":0.0000033152803,"teacher_disagreement_score":0.9846708,"about_ca_system_score_codex":0.000009879388,"about_ca_system_score_gemma":0.000120956814,"threshold_uncertainty_score":0.49210015},"labels":[],"label_agreement":null},{"id":"W3082540542","doi":"10.3389/fphar.2020.559627","title":"Ketamine Rescues Hippocampal Reelin Expression and Synaptic Markers in the Repeated-Corticosterone Chronic Stress Paradigm","year":2020,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Reelin; Corticosterone; Hippocampal formation; Ketamine; Neuroscience; Antidepressant; Subgranular zone; PI3K/AKT/mTOR pathway; Hippocampus; Psychology; Biology; Endocrinology; Medicine; Internal medicine; Cell biology; Receptor; Stem cell; Signal transduction; Neural stem cell; Hormone","score_opus":0.02167533577608428,"score_gpt":0.26635181487975335,"score_spread":0.24467647910366908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082540542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889883,0.0024533086,0.00029091627,0.0064339284,0.00083359226,0.0006409533,0.00001397565,0.00005957726,0.00028546626],"genre_scores_gemma":[0.993616,0.0011628701,0.0002009952,0.0047592786,0.00012553274,0.0000817786,0.0000053241247,0.00002083128,0.000027386859],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975372,0.00079501007,0.00037459325,0.00061215466,0.0001949641,0.00048610693],"domain_scores_gemma":[0.99931854,0.0002692072,0.00010603523,0.00018806956,0.000006222105,0.00011192442],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024805212,0.00020760063,0.00029594748,0.00014865289,0.00008583596,0.000034936216,0.00047809613,0.00011497844,0.00009111152],"category_scores_gemma":[0.0002452348,0.00016470201,0.000039481845,0.00043312856,0.0003416318,0.00017280277,0.00013214693,0.0004974337,0.00000895066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023698187,0.0004185763,0.028849225,0.00024013496,0.000037988393,0.0011826778,0.00530866,0.0007338569,0.86234105,0.00007993136,0.074972585,0.02346552],"study_design_scores_gemma":[0.031800076,0.0033744578,0.115955345,0.00040907995,0.000176312,0.00019355555,0.008669659,0.098400466,0.701306,0.0032657853,0.034227353,0.0022219154],"about_ca_topic_score_codex":0.000012560498,"about_ca_topic_score_gemma":0.000017681868,"teacher_disagreement_score":0.16103503,"about_ca_system_score_codex":0.00008226804,"about_ca_system_score_gemma":0.000051104445,"threshold_uncertainty_score":0.6716353},"labels":[],"label_agreement":null},{"id":"W3084800981","doi":"10.1016/j.jad.2020.09.025","title":"Depression and inflammation among children and adolescents: A meta-analysis","year":2020,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":266,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Alberta Children's Hospital; University of Calgary; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Meta-analysis; Inflammation; Depression (economics); Psychology; Medicine; Clinical psychology; Psychiatry; Internal medicine","score_opus":0.026827763956732368,"score_gpt":0.2994509010035091,"score_spread":0.2726231370467767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3084800981","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0029743128,0.99572897,0.00036254956,0.00007012719,0.000052424144,0.0006970019,0.00002813341,0.000016926975,0.00006952574],"genre_scores_gemma":[0.038771797,0.9610245,0.000029340204,0.000055396587,0.000057713853,0.000014226044,0.0000047455082,0.00003435849,0.000007888468],"study_design_codex":"design_other","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99757445,0.0007364583,0.00061575905,0.00048149846,0.00039409377,0.0001977308],"domain_scores_gemma":[0.99792194,0.0003819156,0.0013003248,0.0001643223,0.0000472508,0.00018425216],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026903566,0.00042602883,0.0024365871,0.00066117884,0.000119127886,0.00012692582,0.0002593497,0.0001841193,0.000025236295],"category_scores_gemma":[0.0008375133,0.00028533235,0.0016214187,0.0010287557,0.00019905249,0.00039977807,0.00012619015,0.0005948347,0.0000028328222],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025515372,0.000064969056,0.0010886046,0.0011380335,0.019227708,0.0000132653995,0.0002004645,0.000011491675,0.00001500893,0.000019117622,0.00007519952,0.9781206],"study_design_scores_gemma":[0.003900655,0.0009335965,0.061735343,0.0036794958,0.802442,0.00039373236,0.00028824017,0.00014329332,0.0002252319,0.0010824815,0.1227181,0.0024578406],"about_ca_topic_score_codex":0.000019177438,"about_ca_topic_score_gemma":0.00006341661,"teacher_disagreement_score":0.97566277,"about_ca_system_score_codex":0.00003552069,"about_ca_system_score_gemma":0.000064818254,"threshold_uncertainty_score":0.9999599},"labels":[],"label_agreement":null},{"id":"W3085386788","doi":"10.1177/1545968320953671","title":"Serum Kynurenines Correlate With Depressive Symptoms and Disability in Poststroke Patients: A Cross-sectional Study","year":2020,"lang":"en","type":"article","venue":"Neurorehabilitation and neural repair","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Hospital Anxiety and Depression Scale; Stroke (engine); Depression (economics); Internal medicine; Functional Independence Measure; Anxiety; Pittsburgh Sleep Quality Index; Montreal Cognitive Assessment; Medicine; Psychology; Kynurenine; Cross-sectional study; Activities of daily living; Physical therapy; Cognition; Psychiatry; Disease; Cognitive impairment; Sleep quality; Pathology","score_opus":0.016836250067218735,"score_gpt":0.26947716473172556,"score_spread":0.25264091466450683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3085386788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979768,0.00001632411,0.0000022805605,0.0007351726,0.00010135283,0.00091226475,0.000028546978,0.00018317565,0.000044122604],"genre_scores_gemma":[0.9987622,0.0000035572814,0.000018420245,0.0011074404,0.000019497598,0.000052100153,0.0000028810794,0.000018383298,0.00001553454],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979863,0.00030648848,0.00033825389,0.0008418271,0.00030829853,0.00021881163],"domain_scores_gemma":[0.99882495,0.00070974394,0.000089553636,0.00016193748,0.00005536507,0.00015842191],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081997445,0.00020495367,0.0001907969,0.000049537546,0.00014989663,0.00008587808,0.00009394568,0.000051700466,0.000019131561],"category_scores_gemma":[0.0016023974,0.0001628002,0.00005250718,0.00032814092,0.00048541796,0.0004028209,0.000086006876,0.00023816599,0.0000024738986],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005644352,0.00036194615,0.99511075,0.0000366782,0.0000031554032,0.00000984758,0.0012484031,0.00011761219,0.0015657437,0.000047602993,0.000008998446,0.0009248538],"study_design_scores_gemma":[0.002818365,0.0024798813,0.9904176,0.000005911713,0.000004941809,0.0000064906058,0.00020943717,0.003603723,0.00022153555,0.000048534348,0.000020686808,0.00016287826],"about_ca_topic_score_codex":0.000021974885,"about_ca_topic_score_gemma":0.000054185806,"teacher_disagreement_score":0.0046931086,"about_ca_system_score_codex":0.00001892034,"about_ca_system_score_gemma":0.000013879247,"threshold_uncertainty_score":0.66388},"labels":[],"label_agreement":null},{"id":"W3086649631","doi":"10.3390/nu12092846","title":"Nutritional Therapy to Modulate Tryptophan Metabolism and Aryl Hydrocarbon-Receptor Signaling Activation in Human Diseases","year":2020,"lang":"en","type":"review","venue":"Nutrients","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Amsterdam University Medical Centers; Crohn's and Colitis Foundation","keywords":"Aryl hydrocarbon receptor; Signal transduction; Tryptophan; Kynurenine; Kynurenine pathway; Receptor; Biology; Metabolic pathway; Metabolism; Cell biology; Biochemistry; Chemistry; Transcription factor; Amino acid; Gene","score_opus":0.05046261146191561,"score_gpt":0.313426899895274,"score_spread":0.2629642884333584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3086649631","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07097655,0.92597646,0.00003103441,0.00017201604,0.00027746742,0.002097529,0.00024747272,0.00013231472,0.000089165624],"genre_scores_gemma":[0.04186163,0.95643556,0.000050787465,0.00069482817,0.00033450229,0.00033520933,0.00016477967,0.00008558838,0.000037086964],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99743867,0.00019487683,0.0005299012,0.00096965255,0.0004826616,0.00038424492],"domain_scores_gemma":[0.9990308,0.00021204313,0.00021925395,0.00023721885,0.00001999981,0.00028068418],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006526585,0.0004889654,0.0010609297,0.0004448852,0.0001628973,0.00012093948,0.00039548613,0.0001956216,0.000073837895],"category_scores_gemma":[0.00019289796,0.00044592007,0.00024756812,0.0009905142,0.00007541469,0.00021902661,0.00011177498,0.00034319283,0.00004774733],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022373782,0.0014957944,0.000044973513,0.0037011004,0.000082661,0.000033255044,0.00051911204,0.00000885245,0.04811088,0.0027257032,0.0007511779,0.94230276],"study_design_scores_gemma":[0.0021549368,0.00010139176,0.00018067351,0.0034611183,0.000043391643,0.0000029068538,0.000016844906,0.00001618988,0.009968819,0.0019338318,0.9813852,0.0007347182],"about_ca_topic_score_codex":0.000008708051,"about_ca_topic_score_gemma":4.192649e-7,"teacher_disagreement_score":0.980634,"about_ca_system_score_codex":0.0000865426,"about_ca_system_score_gemma":0.000081881466,"threshold_uncertainty_score":0.99979925},"labels":[],"label_agreement":null},{"id":"W3086680778","doi":"10.1038/s41386-020-00844-z","title":"Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications","year":2020,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Regione Autonoma della Sardegna; Fondazione di Sardegna; Fondazione Banco di Sardegna","keywords":"Major depressive disorder; Internal medicine; Medicine; Schizophrenia (object-oriented programming); Bipolar disorder; Mood disorders; Population; Cohort; Pathophysiology; Mood; Psychiatry; Gastroenterology; Oncology; Anxiety; Lithium (medication)","score_opus":0.01592102269277465,"score_gpt":0.2886380374392347,"score_spread":0.27271701474646004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3086680778","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95677966,0.00027711166,0.000012151756,0.04122785,0.0003356883,0.00062606786,0.0000100101615,0.00006734938,0.00066410634],"genre_scores_gemma":[0.97647154,0.0011531947,0.00007599571,0.022098096,0.000057385572,0.00008924291,5.1921194e-7,0.000024559351,0.000029446479],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9978807,0.0005468717,0.00033184062,0.0007185807,0.00018367224,0.00033831163],"domain_scores_gemma":[0.9991451,0.000368993,0.00006333142,0.00014035546,0.000013007454,0.0002692253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014831465,0.00018658926,0.00020073603,0.0003646455,0.000076210476,0.00002243424,0.00021649576,0.00009609213,0.000102027865],"category_scores_gemma":[0.00040657455,0.00020446416,0.000025012638,0.0011471303,0.00016404007,0.00013663161,0.00007299692,0.0003905953,0.00005830588],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0050184415,0.00027242294,0.03666132,0.00007950224,0.0000043183595,0.000086124746,0.0018792817,0.00009769214,0.93999195,0.00020374989,0.00380031,0.011904864],"study_design_scores_gemma":[0.007459472,0.00044553922,0.9704863,0.000014597653,0.000007982013,0.000037116002,0.00014631111,0.00032997,0.0005739321,0.00064643193,0.019526584,0.00032576363],"about_ca_topic_score_codex":0.000007109447,"about_ca_topic_score_gemma":0.000094025265,"teacher_disagreement_score":0.939418,"about_ca_system_score_codex":0.000031904307,"about_ca_system_score_gemma":0.000074176016,"threshold_uncertainty_score":0.83378065},"labels":[],"label_agreement":null},{"id":"W3086892435","doi":"10.1016/s2215-0366(20)30391-6","title":"Trial failures of anti-inflammatory drugs in depression – Authors' reply","year":2020,"lang":"en","type":"letter","venue":"The Lancet Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institutes of Health; Fondation Brain Canada; Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation; Patient-Centered Outcomes Research Institute","keywords":"Depression (economics); Minocycline; Celecoxib; Placebo; Medicine; Antidepressant; Inflammation; Randomized controlled trial; Internal medicine; Clinical trial; Psychiatry; Alternative medicine; Pathology","score_opus":0.02754372661871976,"score_gpt":0.2756379280870298,"score_spread":0.24809420146831004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3086892435","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08659616,0.00041518695,0.0000059431845,0.9037299,0.004843991,0.00086984294,0.000066712295,0.00018039205,0.003291869],"genre_scores_gemma":[0.091768116,0.00016479513,0.00019863344,0.8919094,0.0152255725,0.00006718897,0.000025861342,0.00009940211,0.00054101256],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969131,0.0006228911,0.00060670206,0.0007347133,0.0006043989,0.0005181931],"domain_scores_gemma":[0.9980207,0.00035387644,0.0005001063,0.0010634797,0.000013777902,0.000048035465],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00030594072,0.00035615562,0.0007483663,0.00015198765,0.00010861155,0.00005645278,0.0014534619,0.00040514927,0.00009842615],"category_scores_gemma":[0.00034664397,0.00024863376,0.00024953397,0.00040743136,0.00025443995,0.00009216829,0.00019062217,0.0023098427,0.00007589599],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019840477,0.00004265431,0.00071982964,0.00027304582,0.000009939927,0.000032050113,0.00044480176,0.0000041305875,0.0018093474,0.00027316547,0.9941686,0.00023837869],"study_design_scores_gemma":[0.017693093,0.0001222011,0.0016383716,0.00038629305,0.000027539627,0.000009907924,0.0001304003,0.000031470518,0.0035373038,0.0074731894,0.96842104,0.00052919117],"about_ca_topic_score_codex":0.000029495224,"about_ca_topic_score_gemma":0.000012692349,"teacher_disagreement_score":0.025747571,"about_ca_system_score_codex":0.00001800968,"about_ca_system_score_gemma":0.00019353736,"threshold_uncertainty_score":0.9999966},"labels":[],"label_agreement":null},{"id":"W3088795043","doi":"10.1016/j.jad.2020.09.084","title":"Oxidative DNA damage is increased in older adults with a major depressive episode: A preliminary study","year":2020,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Oxidative stress; DNA damage; Internal medicine; Depression (economics); Medicine; Neurocognitive; Late life depression; Young adult; Endocrinology; Psychiatry; Cognition; Biology; DNA; Biochemistry","score_opus":0.009202673438161044,"score_gpt":0.24839894682065203,"score_spread":0.239196273382491,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3088795043","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99588674,0.00013277339,0.00042601014,0.0014086708,0.000057857145,0.0014536602,0.000018987543,0.000028836968,0.000586488],"genre_scores_gemma":[0.99795663,0.000022720636,0.00007584518,0.0017980564,0.00004292504,0.000047264057,0.0000010297542,0.0000445804,0.000010935168],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99742055,0.00064181944,0.00042638773,0.00054355664,0.0005898836,0.00037779444],"domain_scores_gemma":[0.9982084,0.0006933496,0.00053308747,0.00020017086,0.00012399959,0.00024100342],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018872414,0.00033625602,0.0004964511,0.00029201814,0.00011959311,0.00005827468,0.000481934,0.00007572259,0.00011006118],"category_scores_gemma":[0.0013517209,0.00025924094,0.00014751837,0.0010903784,0.00019855416,0.0006253623,0.00011153983,0.0006028368,0.000013526654],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.043009914,0.016977765,0.5937898,0.00042207615,0.00059235806,0.003163766,0.2259454,0.0006991939,0.07998875,0.00009443644,0.0050975587,0.030218937],"study_design_scores_gemma":[0.027235877,0.010995811,0.8574635,0.0003503793,0.000093254195,0.000044630604,0.04018691,0.00070701085,0.06205323,0.00023843498,0.00004671855,0.0005842693],"about_ca_topic_score_codex":0.0001967008,"about_ca_topic_score_gemma":0.00049379095,"teacher_disagreement_score":0.26367363,"about_ca_system_score_codex":0.0000663275,"about_ca_system_score_gemma":0.00013100864,"threshold_uncertainty_score":0.999986},"labels":[],"label_agreement":null},{"id":"W3089368853","doi":"10.1016/j.pnpbp.2020.110123","title":"Neuroinflammatory and behavioral susceptibility profile of mice exposed to social stress towards cocaine effects","year":2020,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Agencia Estatal de Investigación; European Regional Development Fund; Instituto de Salud Carlos III; Ministry of Health, British Columbia; Ministerio de Economía y Competitividad; European Commission; Plan Nacional sobre Drogas; Ministry of Economy","keywords":"Social defeat; Psychology; Coping (psychology); Social stress; Conditioned place preference; Immune system; Cue reactivity; Clinical psychology; Immunology; Addiction; Developmental psychology; Neuroscience; Medicine; Craving","score_opus":0.043545869275420084,"score_gpt":0.33778853166017053,"score_spread":0.29424266238475044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3089368853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900277,0.00055117276,0.000006408892,0.007243413,0.00077489915,0.0011348086,0.000062085135,0.000113520386,0.0000859877],"genre_scores_gemma":[0.9917837,0.00010464624,0.00024939678,0.00754915,0.00018291533,0.00010498889,0.000003963536,0.000018308858,0.0000029374366],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99731976,0.0005891517,0.00045575274,0.0010101573,0.00016104606,0.00046411154],"domain_scores_gemma":[0.99916005,0.00027112296,0.00015387686,0.000120259276,0.000026878919,0.0002677903],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015695937,0.00031060042,0.0004616297,0.00009651932,0.00014170136,0.000024223395,0.00035414164,0.00024139437,0.00005736756],"category_scores_gemma":[0.00018898954,0.0002544427,0.00008138735,0.0004379692,0.0009325802,0.0000845981,0.00025141516,0.00051442813,0.000006028723],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037274456,0.0011981981,0.73994696,0.0003665461,0.000008784243,0.0000755984,0.000585128,0.0000011516754,0.23563914,0.00041485947,0.00075119763,0.017284969],"study_design_scores_gemma":[0.004492752,0.0024864303,0.9692476,0.000022224694,0.000018072704,0.00001293724,0.00011020552,0.00008607567,0.022598539,0.00035052863,0.00022996563,0.00034466368],"about_ca_topic_score_codex":0.0000014852435,"about_ca_topic_score_gemma":0.000005084277,"teacher_disagreement_score":0.22930062,"about_ca_system_score_codex":0.000007237341,"about_ca_system_score_gemma":0.00004077501,"threshold_uncertainty_score":0.99999076},"labels":[],"label_agreement":null},{"id":"W3089789513","doi":"10.3390/nu12103019","title":"C-Reactive Protein as a Possible Predictor of Trail-Making Performance in Individuals with Psychiatric Disorders","year":2020,"lang":"en","type":"article","venue":"Nutrients","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Trail Making Test; Cognition; Body mass index; Cognitive flexibility; Kynurenine; Stroop effect; Medicine; Psychiatry; Clinical psychology; Psychology; Internal medicine; Cognitive impairment","score_opus":0.01562302601402398,"score_gpt":0.2452786020510332,"score_spread":0.2296555760370092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3089789513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99316245,0.000037207803,0.00004187381,0.00052647234,0.000045039036,0.00090718013,0.00002514247,0.00005770888,0.005196945],"genre_scores_gemma":[0.9991731,0.000010955081,0.00025012853,0.0004043695,0.000023609262,0.000073522984,0.0000019679796,0.000022622376,0.000039706505],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99849784,0.00006709894,0.00025050444,0.00042518208,0.0004486701,0.00031072428],"domain_scores_gemma":[0.99952114,0.000047658214,0.0001721139,0.0001539011,0.000017154522,0.00008805452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006534262,0.00016708829,0.00020286732,0.00016932841,0.00006614283,0.000023988454,0.00032606814,0.00006336897,0.00004207583],"category_scores_gemma":[0.00020666391,0.00014149412,0.000043424883,0.0013095081,0.0001199372,0.0003112887,0.00005114837,0.00021419366,0.000028112023],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009405351,0.0011631821,0.96214145,0.00031042387,0.00001808108,0.000007500564,0.00738587,0.000120869096,0.022589533,0.0012528878,0.00009537742,0.0039742715],"study_design_scores_gemma":[0.012709673,0.0037913667,0.7325939,0.0005089102,0.000024103188,0.000007948652,0.0015914642,0.0010539552,0.24126808,0.0020377599,0.0035999233,0.00081288605],"about_ca_topic_score_codex":0.000009496812,"about_ca_topic_score_gemma":0.0000075055705,"teacher_disagreement_score":0.22954755,"about_ca_system_score_codex":0.00002196839,"about_ca_system_score_gemma":0.00009470972,"threshold_uncertainty_score":0.57699627},"labels":[],"label_agreement":null},{"id":"W3090124015","doi":"10.1101/2020.10.05.326306","title":"Depressive-like behaviors induced by somatostatin-positive GABA neuron silencing are rescued by alpha 5 GABA-A receptor potentiation","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression; Campbell Family Mental Health Research Institute; University of Pennsylvania","keywords":"Gene silencing; Neuroscience; Allosteric modulator; Somatostatin; Anhedonia; Psychology; Antidepressant; Internal medicine; Receptor; Endocrinology; Allosteric regulation; Biology; Medicine; Hippocampus; Biochemistry","score_opus":0.017891672271419294,"score_gpt":0.23040276873393753,"score_spread":0.21251109646251823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3090124015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98947835,0.00047507425,0.00072602346,0.0010126927,0.0018582171,0.0016745195,0.0037708292,0.0009927528,0.000011528703],"genre_scores_gemma":[0.99628896,0.00025483724,0.00042411956,0.0021433304,0.00021845014,0.00032275106,0.000009349263,0.00032588412,0.00001232999],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99337417,0.00073912356,0.00096229644,0.0027599817,0.0010920728,0.0010723693],"domain_scores_gemma":[0.99613935,0.0002495152,0.0013641764,0.0012774207,0.0003325723,0.000636979],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026567437,0.0011188948,0.000900441,0.00030502953,0.00054292346,0.00059794926,0.0012556906,0.0008027176,0.000101586156],"category_scores_gemma":[0.0012083362,0.0013002475,0.0003146058,0.00094967743,0.00020677943,0.0005513715,0.00085603585,0.0017081975,0.00017602465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008264016,0.00028870592,0.0009395029,0.00017768811,0.00004419288,0.0000803166,0.00007002654,0.000014098868,0.9881947,0.000038473212,0.010061688,0.000007952436],"study_design_scores_gemma":[0.0010719823,0.00012484536,0.024805266,0.00040466886,0.000102140475,5.2257143e-8,0.000032592652,0.00025638033,0.971012,0.0000021713477,0.0008897853,0.0012981042],"about_ca_topic_score_codex":0.000096737116,"about_ca_topic_score_gemma":0.0000044836065,"teacher_disagreement_score":0.023865763,"about_ca_system_score_codex":0.00036347506,"about_ca_system_score_gemma":0.00044529076,"threshold_uncertainty_score":0.9989447},"labels":[],"label_agreement":null},{"id":"W3091222764","doi":"10.1038/s41598-020-73043-x","title":"Cognitive impairment and C-reactive protein in clinically stable schizophrenia outpatients: a focus on sex differences","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III","keywords":"Cognitive impairment; Schizophrenia (object-oriented programming); Cognition; Medicine; Focus (optics); Clinical psychology; Psychiatry; Psychology; Bioinformatics; Biology","score_opus":0.036304718339631545,"score_gpt":0.27750835203497315,"score_spread":0.2412036336953416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091222764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952312,0.00001760499,0.000025238522,0.0006561528,0.0005503621,0.0011592883,0.000013192509,0.000073142925,0.002273789],"genre_scores_gemma":[0.99896395,0.0000016910741,0.00006925216,0.00037614166,0.00002637207,0.00008888509,0.000004261461,0.000013685348,0.0004557415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99693096,0.0001750568,0.000563357,0.00133997,0.00060972234,0.00038091524],"domain_scores_gemma":[0.99893886,0.00019612034,0.0003107797,0.00027072,0.000050345992,0.00023317937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050336757,0.00019930261,0.0002668341,0.00013417297,0.00021390757,0.00028953305,0.00014459158,0.00006467942,0.000071298804],"category_scores_gemma":[0.0020217402,0.00016260607,0.000059971586,0.0006043675,0.0004530334,0.00024144011,0.00014282459,0.00025185623,0.00003893172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0054715006,0.0057226242,0.17534502,0.00027370872,0.00006212654,0.005101792,0.031365067,0.000024857323,0.69368637,0.001550029,0.0034240852,0.07797283],"study_design_scores_gemma":[0.005121869,0.0034014878,0.07160396,0.00064141606,0.00002149914,0.00006509883,0.0041153235,0.0009025897,0.8666242,0.045232985,0.0010786164,0.0011909847],"about_ca_topic_score_codex":0.00002914814,"about_ca_topic_score_gemma":0.00002420365,"teacher_disagreement_score":0.17293781,"about_ca_system_score_codex":0.000031719035,"about_ca_system_score_gemma":0.00014943593,"threshold_uncertainty_score":0.6630883},"labels":[],"label_agreement":null},{"id":"W3091693300","doi":"10.1096/fj.202002065","title":"The 2020 FASEB Science Research Conference on Translational Neuroimmunology: From Mechanisms to Therapeutics, June 29‐30, 2020","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Neuroimmunology; Neuroscience; Medicine; Biology","score_opus":0.12171575132795806,"score_gpt":0.3404264243207147,"score_spread":0.21871067299275662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091693300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6514702,0.0003205342,0.0043189027,0.33805487,0.0015761574,0.00069058995,0.000099435725,0.00009571364,0.0033736308],"genre_scores_gemma":[0.98587954,0.00040302,0.00013738632,0.01293393,0.0003335926,0.000009632466,0.0000012233313,0.000023987739,0.00027769268],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99591804,0.0008602136,0.0003459305,0.0005633033,0.001552096,0.0007603947],"domain_scores_gemma":[0.9975614,0.0013578458,0.00011802854,0.00044455598,0.00019643064,0.00032172425],"candidate_categories":["sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013732603,0.00021320787,0.00017765973,0.00008842969,0.0028865368,0.0007497342,0.002579787,0.00006247005,0.0006198009],"category_scores_gemma":[0.00094963855,0.00012418334,0.00010289073,0.0012285501,0.0013845079,0.00021288855,0.0002269104,0.0015864489,0.0008129987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031218427,0.000042478387,0.000008194318,9.866334e-7,0.000010252306,0.00004014804,0.0017630052,0.00011240857,0.9732434,0.016803805,0.0014707505,0.0061923796],"study_design_scores_gemma":[0.0010392107,0.0007049627,0.0026845434,0.00003332645,0.000013475076,0.000077111945,0.0019571895,0.0048352554,0.9236347,0.055529866,0.009194388,0.00029593392],"about_ca_topic_score_codex":0.000011270762,"about_ca_topic_score_gemma":0.000015074905,"teacher_disagreement_score":0.33440936,"about_ca_system_score_codex":0.000044134904,"about_ca_system_score_gemma":0.0005185038,"threshold_uncertainty_score":0.999965},"labels":[],"label_agreement":null},{"id":"W3092338564","doi":"10.1155/2020/3497920","title":"Molecular Mechanisms of Glial Cells Related Signaling Pathways Involved in the Neuroinflammatory Response of Depression","year":2020,"lang":"en","type":"review","venue":"Mediators of Inflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Western University; Mount Sinai Hospital","funders":"Fundamental Research Fund of Shandong University; Capital Medical University; Shandong University","keywords":"Neuroinflammation; Microglia; Neuroscience; Pathological; Depression (economics); Signal transduction; Biology; Medicine; Immunology; Cell biology; Inflammation; Pathology","score_opus":0.024265486228673402,"score_gpt":0.25455038452506784,"score_spread":0.23028489829639442,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092338564","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.63657707,0.35943177,0.0003160046,0.00006513088,0.00059939956,0.0027247642,0.00009659824,0.00008116195,0.00010810019],"genre_scores_gemma":[0.4697741,0.52970874,0.00017817337,0.00004489975,0.000057687255,0.00009423922,0.00004185218,0.00009736784,0.000002937197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99455214,0.0022332615,0.0017162792,0.00043209956,0.0008441552,0.00022207948],"domain_scores_gemma":[0.9957101,0.0016875566,0.0019733345,0.0005014875,0.0000640026,0.00006356701],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013154787,0.00035260635,0.0011412065,0.0004825537,0.000036262183,0.0000130082835,0.0007979118,0.00036541044,0.000014461617],"category_scores_gemma":[0.0030938936,0.00026390253,0.00041033028,0.000993474,0.00016180532,0.00014164197,0.00012504448,0.0004532976,0.000009452535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017071354,0.000057897778,0.000002649765,0.005216939,0.000013423838,0.000070366805,0.0013800313,0.00013118048,0.95624256,0.0013254011,0.000011734963,0.035377104],"study_design_scores_gemma":[0.00055936695,0.00012616414,0.0000130302615,0.0031769953,0.000089973706,0.0000036912065,0.00017915902,0.00016957818,0.9912865,0.0009826594,0.0031814112,0.00023147537],"about_ca_topic_score_codex":0.0000042351808,"about_ca_topic_score_gemma":0.0000013338545,"teacher_disagreement_score":0.17027697,"about_ca_system_score_codex":0.000039453742,"about_ca_system_score_gemma":0.00037250746,"threshold_uncertainty_score":0.99998134},"labels":[],"label_agreement":null},{"id":"W3093022522","doi":"10.1186/s12916-020-01749-w","title":"Endothelial dysfunction in neuroprogressive disorders—causes and suggested treatments","year":2020,"lang":"en","type":"review","venue":"BMC Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Health and Medical Research Council","keywords":"Endothelial dysfunction; Oxidative stress; NADPH oxidase; Cell biology; Medicine; Enos; Reactive oxygen species; Apocynin; PI3K/AKT/mTOR pathway; Nitric oxide; Internal medicine; Nitric oxide synthase; Biology; Signal transduction","score_opus":0.0707644695962379,"score_gpt":0.33655902361021345,"score_spread":0.26579455401397556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3093022522","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025874397,0.99670607,0.000014490237,0.00020381343,0.0005426581,0.0012191753,0.000039354854,0.000109808156,0.0009058626],"genre_scores_gemma":[0.00039912583,0.99844384,0.000017076076,0.00028189548,0.00027942957,0.00013437214,0.000035115827,0.000060005103,0.00034911218],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99762815,0.00041109681,0.00049799035,0.00084545225,0.00031313847,0.0003041667],"domain_scores_gemma":[0.99850136,0.0007871932,0.00027351503,0.0002742329,0.000008459016,0.00015525887],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007787859,0.00046641217,0.0012270389,0.00027381294,0.00006741115,0.000022113738,0.00022839727,0.00015609317,0.00011414646],"category_scores_gemma":[0.001596904,0.0003124751,0.00011553173,0.0006487022,0.00030598298,0.00007789428,0.00008779108,0.0003288606,0.000072101924],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038747796,0.00009240006,0.0001069845,0.0032083867,0.00001400392,0.00012377664,0.00014616175,1.3089209e-7,0.00006050312,0.00013515877,0.00033572043,0.995738],"study_design_scores_gemma":[0.0024713106,0.00052062527,0.00026461194,0.0048013045,0.00021932324,0.00007838341,0.00006113507,0.000013597681,0.000021837403,0.00010061291,0.99113697,0.0003102859],"about_ca_topic_score_codex":0.00003183193,"about_ca_topic_score_gemma":0.000075799566,"teacher_disagreement_score":0.9954277,"about_ca_system_score_codex":0.0000469711,"about_ca_system_score_gemma":0.0001265591,"threshold_uncertainty_score":0.9999327},"labels":[],"label_agreement":null},{"id":"W3093971864","doi":"10.1101/2020.10.25.20219188","title":"Mendelian randomization integrating GWAS and eQTL data revealed genes pleiotropically associated with major depressive disorder","year":2020,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"National Institute on Aging; National Institutes of Health; National Key Research and Development Program of China; China Scholarship Council","keywords":"Mendelian randomization; Expression quantitative trait loci; Major depressive disorder; Genome-wide association study; Biology; Genetics; Quantitative trait locus; Gene; Genetic association; Computational biology; Single-nucleotide polymorphism; Genetic variants; Neuroscience; Genotype","score_opus":0.04375164662629814,"score_gpt":0.2777839971117346,"score_spread":0.2340323504854365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3093971864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.973457,0.00083025376,0.019071963,0.0034742553,0.00030952913,0.0014089235,0.0004292637,0.00033810775,0.00068071234],"genre_scores_gemma":[0.9963833,0.0004876326,0.0014514204,0.00079384376,0.00011197553,0.0000875086,0.0004195127,0.00007826056,0.00018652793],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9965887,0.0005910703,0.0004887484,0.0014772468,0.0004817807,0.0003724699],"domain_scores_gemma":[0.99778867,0.0006082012,0.0005010592,0.00084207265,0.00008422906,0.00017574817],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024931552,0.00045327688,0.00063620094,0.000113077826,0.0002514822,0.00026259417,0.0010950564,0.0002597179,0.000060063234],"category_scores_gemma":[0.0059474935,0.00034526066,0.00006796826,0.00034677045,0.00022803042,0.00020337637,0.001563291,0.0007082453,0.000009443562],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005134289,0.0011932398,0.4444425,0.0017742654,0.0011347733,0.0007467016,0.0057692197,0.0026201655,0.482487,0.0031871162,0.0048166495,0.046694078],"study_design_scores_gemma":[0.107303716,0.0013064436,0.39051464,0.0059840884,0.0020185104,0.00012587718,0.0020457,0.32988778,0.123239666,0.019246392,0.008683749,0.009643458],"about_ca_topic_score_codex":0.000068347515,"about_ca_topic_score_gemma":0.00051090796,"teacher_disagreement_score":0.35924733,"about_ca_system_score_codex":0.00003258216,"about_ca_system_score_gemma":0.00015608655,"threshold_uncertainty_score":0.9998999},"labels":[],"label_agreement":null},{"id":"W3094138688","doi":"10.1016/j.biopsych.2020.10.009","title":"Cord Serum Cytokines at Birth and Children’s Anxiety-Depression Trajectories From 3 to 8 Years: The EDEN Mother–Child Cohort","year":2020,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Research Unit on Children's Psychosocial Maladjustment","funders":"Fondation de France; Institut National de la Santé et de la Recherche Médicale; CHIST-ERA; Université Paris-Sud; Agence Nationale de la Recherche","keywords":"Anxiety; Depression (economics); Offspring; Pregnancy; Medicine; Odds ratio; Cohort; Cohort study; Confounding; Psychology; Psychiatry; Pediatrics; Clinical psychology; Internal medicine","score_opus":0.022054350836495578,"score_gpt":0.24224385657561118,"score_spread":0.2201895057391156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094138688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98533076,0.0006808018,0.000024170391,0.011810868,0.00051903364,0.00044787978,0.00023179594,0.00019570612,0.0007590008],"genre_scores_gemma":[0.97940457,0.000302721,0.0001660132,0.019408418,0.0006140317,0.000019542314,0.000008778421,0.000018627597,0.0000572935],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985075,0.00013867617,0.00018742264,0.00070724747,0.00017804453,0.0002811269],"domain_scores_gemma":[0.99937683,0.00011031335,0.000064208354,0.0002539768,0.000007390913,0.00018728018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059037695,0.00021052008,0.00020860671,0.0000196231,0.00021945742,0.000061938066,0.00042278416,0.00013984628,0.0004132555],"category_scores_gemma":[0.00020155101,0.00012108701,0.00008458736,0.00022849644,0.0002008243,0.000051774732,0.00025891326,0.00020772048,0.0001315711],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038914997,0.0000639432,0.9689563,0.000003910687,0.000012310885,0.0000014231557,0.00026259295,0.000003657906,0.01872841,0.00030664515,0.008649584,0.002622093],"study_design_scores_gemma":[0.00042172335,0.00023890716,0.9773597,0.000013056812,0.000005623013,0.000008262241,0.000105979176,0.000010101875,0.0027293684,0.00056802796,0.018330645,0.00020861762],"about_ca_topic_score_codex":0.000030232412,"about_ca_topic_score_gemma":0.00003254066,"teacher_disagreement_score":0.015999041,"about_ca_system_score_codex":0.000010040431,"about_ca_system_score_gemma":0.000013572979,"threshold_uncertainty_score":0.4937785},"labels":[],"label_agreement":null},{"id":"W3094213593","doi":"10.1016/s2215-0366(20)30255-8","title":"Neuroinflammation in psychiatric disorders: PET imaging and promising new targets","year":2020,"lang":"en","type":"review","venue":"The Lancet Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":266,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; University of Toronto","funders":"National Institute on Aging; National Institutes of Health","keywords":"Translocator protein; Neuroinflammation; Major depressive disorder; Psychosis; Schizophrenia (object-oriented programming); Neuroscience; Medicine; Psychology; Psychiatry; Neuroimaging; Inflammation; Internal medicine; Cognition","score_opus":0.034577284154627304,"score_gpt":0.3065328981910048,"score_spread":0.2719556140363775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094213593","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011592302,0.98003304,0.00005045173,0.014696772,0.0014041726,0.0011601036,0.00001589435,0.00017666417,0.002346982],"genre_scores_gemma":[0.00013703547,0.9961614,0.0006757614,0.0011810851,0.0016404156,0.00003644193,0.000008318216,0.00008648796,0.00007302479],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99732107,0.0004234976,0.0006259858,0.00083033583,0.00026518677,0.0005339509],"domain_scores_gemma":[0.9986652,0.00021882346,0.00043061966,0.00055727904,0.000004890451,0.00012317338],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023340691,0.0004993251,0.0011543218,0.00022889377,0.00018961736,0.00020958744,0.0007981755,0.00008210012,0.00002943239],"category_scores_gemma":[0.00023388834,0.0003554883,0.00024107707,0.0010196588,0.00010509258,0.00021386518,0.00016908132,0.00090135605,0.00009390555],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025989093,0.000046768142,0.0001896031,0.0046882434,0.000009081873,0.000012118463,0.00022167558,0.0000021336336,0.000008209537,0.0022370832,0.009680826,0.98287827],"study_design_scores_gemma":[0.0008136376,0.000028170803,0.00024160654,0.0020577356,0.00007903247,0.00012812288,0.00004627531,0.0001404075,9.861675e-7,0.01147606,0.9845096,0.00047838397],"about_ca_topic_score_codex":0.000018930528,"about_ca_topic_score_gemma":0.000085464686,"teacher_disagreement_score":0.9823999,"about_ca_system_score_codex":0.00003100368,"about_ca_system_score_gemma":0.0003594396,"threshold_uncertainty_score":0.99988973},"labels":[],"label_agreement":null},{"id":"W3095402560","doi":"10.3389/fimmu.2020.578654","title":"The Antidepressant Mirtazapine Activates Hepatic Macrophages, Facilitating Pathogen Clearance While Limiting Tissue Damage in Mice","year":2020,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Alberta Innovates; Canada Research Chairs; Wenzel Family Foundation; Canadian Liver Foundation; University of Calgary","keywords":"Mirtazapine; Kupffer cell; Inflammation; Macrophage; Innate immune system; Phagocytosis; Immunology; Liver injury; Acquired immune system; Immune system; Biology; Pharmacology; Antidepressant; Endocrinology; In vitro","score_opus":0.018700444384735008,"score_gpt":0.23967947917478136,"score_spread":0.22097903479004635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3095402560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98984176,0.004967773,0.00055409694,0.0027164388,0.0005731493,0.0004041154,0.000026737694,0.000084155814,0.0008317991],"genre_scores_gemma":[0.9955378,0.0010671826,0.002327168,0.00083514344,0.000030698444,0.00004297502,0.0000047734766,0.000029109255,0.00012511865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99772006,0.00053958,0.00042863833,0.0005581302,0.00014391681,0.00060968846],"domain_scores_gemma":[0.9989099,0.0005436608,0.00014081011,0.0003445039,0.000015740781,0.00004537304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021769606,0.00021114264,0.000328284,0.00010749496,0.00022464771,0.00006438704,0.00087017205,0.00011401927,0.000025243738],"category_scores_gemma":[0.0028992263,0.00018444336,0.000047614056,0.00062791543,0.000382524,0.00021914222,0.00027962224,0.00054133526,0.000044516488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002587114,0.000053687567,0.009833829,0.000041085186,0.000010424072,0.00010421084,0.003265009,0.00017923691,0.9522736,0.0001456006,0.0012783492,0.03255625],"study_design_scores_gemma":[0.0040745735,0.0004991682,0.12661447,0.0002070165,0.00000977181,0.000026720547,0.014017273,0.014280295,0.79607606,0.0020617233,0.04121268,0.0009202411],"about_ca_topic_score_codex":0.00009804211,"about_ca_topic_score_gemma":0.000059087335,"teacher_disagreement_score":0.15619753,"about_ca_system_score_codex":0.000050603023,"about_ca_system_score_gemma":0.000035521407,"threshold_uncertainty_score":0.7521382},"labels":[],"label_agreement":null},{"id":"W3097108793","doi":"10.1176/appi.focus.18309","title":"The Neurobiology of Treatment-Resistant Schizophrenia: Paths to Antipsychotic Resistance and A Roadmap for Future Research","year":2020,"lang":"en","type":"article","venue":"FOCUS The Journal of Lifelong Learning in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"H. Lundbeck A/S","keywords":"Schizophrenia (object-oriented programming); Clozapine; Antipsychotic; Psychology; Clinical trial; Psychosis; Neuroscience; Psychiatry; Medicine; Clinical psychology; Internal medicine","score_opus":0.036242844775722344,"score_gpt":0.3144716554417498,"score_spread":0.27822881066602745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3097108793","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93428504,0.0045817285,0.000108515516,0.05962156,0.0008557275,0.00042005494,0.0000069157413,0.000012578199,0.000107860236],"genre_scores_gemma":[0.9963681,0.0015558675,0.00073971855,0.0005402442,0.00061619753,0.000009037832,1.7460766e-7,0.000026627025,0.00014403612],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99734753,0.0011945438,0.0005499193,0.00025162107,0.000272216,0.00038417388],"domain_scores_gemma":[0.9969925,0.002184373,0.00036566722,0.0002190063,0.00010380231,0.00013462074],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012533545,0.00015847526,0.00030005013,0.00015166061,0.00048839534,0.000056740842,0.000592483,0.00007638361,0.00000362833],"category_scores_gemma":[0.0013613803,0.00008749327,0.0001173014,0.0007170283,0.0002447684,0.00007311448,0.00005774082,0.0006890596,0.0000031213006],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.15901753,0.001609565,0.06763341,0.0009682564,0.00042484645,0.00009173359,0.054036364,0.005070154,0.51790094,0.034295585,0.081354134,0.077597454],"study_design_scores_gemma":[0.037943497,0.052150514,0.35124716,0.0021647299,0.00025827516,0.00036099958,0.05104701,0.00096287945,0.03800446,0.038579527,0.42541426,0.0018666765],"about_ca_topic_score_codex":0.0000062743993,"about_ca_topic_score_gemma":0.0002513802,"teacher_disagreement_score":0.4798965,"about_ca_system_score_codex":0.00003100972,"about_ca_system_score_gemma":0.00028191003,"threshold_uncertainty_score":0.37563914},"labels":[],"label_agreement":null},{"id":"W3097404387","doi":"10.2217/pme-2020-0033","title":"Big Data in Severe Mental Illness: the Role of Electronic Monitoring Tools and Metabolomics","year":2020,"lang":"en","type":"review","venue":"Personalized Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Marie Curie","keywords":"Big data; Mental illness; Psychological intervention; Data science; Intervention (counseling); Perspective (graphical); Personalized medicine; Medicine; Computer science; Mental health; Bioinformatics; Psychiatry; Data mining; Artificial intelligence; Biology","score_opus":0.1059765048723285,"score_gpt":0.3441730809566965,"score_spread":0.238196576084368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3097404387","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002484882,0.997567,0.0000030772542,0.0005138498,0.0003214815,0.00066465227,0.00021825894,0.000022103903,0.00044107033],"genre_scores_gemma":[0.0017815803,0.99736667,0.000011851472,0.00017524995,0.00042132396,0.000039333543,0.00008227104,0.00003694737,0.00008479647],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978618,0.00028153928,0.00046069163,0.00063440145,0.00041661152,0.00034495964],"domain_scores_gemma":[0.9984093,0.0007133633,0.00026128266,0.0005240976,0.000010121688,0.000081862185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040882936,0.00032647434,0.0012980324,0.000115791925,0.0000766096,0.000019654084,0.0009604009,0.00011039832,0.000050888022],"category_scores_gemma":[0.0011423514,0.00019329673,0.00009334664,0.00058449263,0.00041209706,0.00010542607,0.00035754914,0.00054759753,0.000005232914],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024315941,0.000020717243,0.000008587524,0.0011659786,0.000034883316,0.000007550614,0.001104585,3.1850533e-8,0.00054651103,0.0005812702,0.000090873145,0.9964147],"study_design_scores_gemma":[0.0008491892,0.000050867104,0.000005747429,0.002317091,0.00020142974,0.00007422884,0.0013663857,0.000026477239,0.00011792439,0.00015727365,0.99463737,0.00019601142],"about_ca_topic_score_codex":0.000042907825,"about_ca_topic_score_gemma":0.000008878119,"teacher_disagreement_score":0.9962187,"about_ca_system_score_codex":0.000062304134,"about_ca_system_score_gemma":0.00026470437,"threshold_uncertainty_score":0.7882412},"labels":[],"label_agreement":null},{"id":"W3098354563","doi":"10.1503/jpn.210027","title":"Elevated clozapine levels and toxic effects after SARS-CoV-2 vaccination","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Fraser Health; BC Mental Health & Substance Use Services; University of British Columbia","funders":"","keywords":"Clozapine; Coronavirus disease 2019 (COVID-19); Psychosis; Medicine; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Coronavirus; Disease; Inflammation; Schizophrenia (object-oriented programming); Immunology; Pharmacology; Virology; Psychiatry; Internal medicine; Outbreak; Infectious disease (medical specialty)","score_opus":0.02496856061148478,"score_gpt":0.2893471231092282,"score_spread":0.26437856249774344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3098354563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937552,0.0012204095,0.00049430894,0.0026410355,0.0016978998,0.000072921684,0.0000036073436,0.00001366226,0.00010095974],"genre_scores_gemma":[0.99257237,0.00051523617,0.00042326216,0.0063020806,0.00009793872,0.000001430075,5.99467e-8,0.000009018324,0.00007861826],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871343,0.00015974056,0.00028549752,0.00032632038,0.00029888266,0.00021609858],"domain_scores_gemma":[0.999397,0.00012347946,0.00019967221,0.00012830368,0.00005642409,0.00009513007],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002003074,0.00013443931,0.00017728955,0.000128814,0.00015583707,0.00013436221,0.00016063779,0.000050095176,0.00001146784],"category_scores_gemma":[0.0006504037,0.000111398476,0.000057402514,0.0005253259,0.00012020223,0.0005196472,0.00006609133,0.0002277844,0.000002056002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000604725,0.000118425145,0.0021552814,0.000053677875,0.0000010695072,0.000102929414,0.000059546375,0.0000020297664,0.99409425,0.000797354,0.00022689701,0.0023280415],"study_design_scores_gemma":[0.0009896486,0.00035733703,0.20557813,0.0000632959,0.000010005363,0.0010738485,0.000021664471,0.00015626759,0.78751576,0.0028911156,0.0012034917,0.00013941868],"about_ca_topic_score_codex":4.421596e-7,"about_ca_topic_score_gemma":0.00000531078,"teacher_disagreement_score":0.20657851,"about_ca_system_score_codex":0.000007925532,"about_ca_system_score_gemma":0.00010978718,"threshold_uncertainty_score":0.4542698},"labels":[],"label_agreement":null},{"id":"W3099005773","doi":"10.1101/2020.11.17.20233635","title":"Glutathione as a molecular marker of functional impairment in patients with at-risk mental state: 7-Tesla <sup>1</sup> H-MRS study","year":2020,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St Joseph's Health Care; Lawson Health Research Institute; Western University","funders":"Schulich School of Medicine and Dentistry; Canadian Institutes of Health Research; Academic Medical Organization of Southwestern Ontario","keywords":"At risk mental state; Glutathione; Schizophrenia (object-oriented programming); Psychosis; Medicine; Clinical psychology; Anterior cingulate cortex; Psychology; Internal medicine; Psychiatry; Cognition; Chemistry","score_opus":0.012212066783926438,"score_gpt":0.23088157721923794,"score_spread":0.2186695104353115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3099005773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99655455,0.00004111335,0.0000764631,0.00023144708,0.00019553225,0.0022238032,0.0002806221,0.00007404357,0.00032241168],"genre_scores_gemma":[0.9990314,0.000023917688,0.00008349405,0.0003780792,0.000016035505,0.0001652309,0.000068467714,0.00006821687,0.0001651236],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9957657,0.000594384,0.0006150057,0.0012291151,0.0013632831,0.00043252154],"domain_scores_gemma":[0.998636,0.00012907092,0.00040263,0.0005762796,0.00006641625,0.00018960252],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031483918,0.00048669797,0.0005311379,0.00024180394,0.00010175499,0.00004349345,0.00048221918,0.00012553886,0.00037364187],"category_scores_gemma":[0.0003008137,0.00042013408,0.00016199682,0.0004595912,0.00019216911,0.0000823753,0.001062786,0.0007202432,0.00010187848],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034336594,0.0047238776,0.96890956,0.00015522078,0.000158348,0.00022825033,0.007129672,0.009299912,0.004908734,0.000026157259,0.00047375011,0.00055283314],"study_design_scores_gemma":[0.0064855986,0.001670539,0.9822532,0.000104356564,0.0000489348,0.0000033557308,0.00069778424,0.0013312986,0.006200834,0.00047953214,0.0001659449,0.00055861607],"about_ca_topic_score_codex":0.00012461611,"about_ca_topic_score_gemma":0.000027768485,"teacher_disagreement_score":0.013343619,"about_ca_system_score_codex":0.00020001412,"about_ca_system_score_gemma":0.00018703137,"threshold_uncertainty_score":0.99982506},"labels":[],"label_agreement":null},{"id":"W3103271459","doi":"10.1016/j.bbi.2020.11.008","title":"Ibrutinib alleviates LPS-induced neuroinflammation and synaptic defects in a mouse model of depression","year":2020,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":258,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Neuroinflammation; Ibrutinib; SNAP25; Inflammasome; Proinflammatory cytokine; Pharmacology; Neuroscience; Medicine; Immunology; Psychology; Inflammation; Biology","score_opus":0.056654927136356746,"score_gpt":0.2740969959075504,"score_spread":0.21744206877119363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3103271459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992033,0.000048493494,0.000016414346,0.0001947611,0.000014312424,0.000350157,0.000010356437,0.00004384367,0.000118345466],"genre_scores_gemma":[0.99954,0.000050187213,0.000053451924,0.0003011762,0.0000035979506,0.000015814669,0.0000029504076,0.000013434258,0.000019407107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908084,0.00017635206,0.00021135858,0.00025441434,0.00011946437,0.00015755235],"domain_scores_gemma":[0.99946743,0.00019438809,0.00007953445,0.00016072564,0.000012323101,0.00008561109],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010813683,0.00012645274,0.00017724725,0.00006898869,0.00007531758,0.00002878955,0.00012815149,0.000070452166,0.000012614599],"category_scores_gemma":[0.00051385304,0.000120166056,0.000030811167,0.00014395111,0.00007477405,0.00019842746,0.0001394708,0.000198695,0.0000022796153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060255858,0.000081822414,0.011924773,0.000044265245,7.7330486e-7,0.0000026117482,0.0010389325,0.000034706885,0.9844011,0.00008052067,0.0000053289946,0.0023249118],"study_design_scores_gemma":[0.0013397175,0.00018075397,0.1454322,0.000029684988,0.0000084756575,0.000004996661,0.00025830336,0.012546933,0.8398972,0.000120950564,0.000003968143,0.0001768081],"about_ca_topic_score_codex":0.000048260063,"about_ca_topic_score_gemma":0.000014255997,"teacher_disagreement_score":0.14450389,"about_ca_system_score_codex":0.000005643154,"about_ca_system_score_gemma":0.000019473633,"threshold_uncertainty_score":0.49002296},"labels":[],"label_agreement":null},{"id":"W3103639177","doi":"10.3390/diagnostics10110926","title":"Type 17 Immune Response Facilitates Progression of Inflammation and Correlates with Cognition in Stable Schizophrenia","year":2020,"lang":"en","type":"article","venue":"Diagnostics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu; Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja","keywords":"Schizophrenia (object-oriented programming); Risperidone; Proinflammatory cytokine; Positive and Negative Syndrome Scale; Interleukin; Medicine; Inflammation; Tumor necrosis factor alpha; Internal medicine; Immune system; Interleukin 18; Immunology; Psychology; Cytokine; Psychosis; Psychiatry","score_opus":0.019796082043560065,"score_gpt":0.25061112090150045,"score_spread":0.23081503885794039,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3103639177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99851334,0.00034640016,0.000037313108,0.000684182,0.00002586819,0.00024653182,0.000021638009,0.000032067845,0.00009264454],"genre_scores_gemma":[0.9993555,0.00030537223,0.00021718444,0.00007134714,0.000007503007,0.000009001588,0.000011514389,0.000007913799,0.000014645179],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993519,0.00009340649,0.00015944066,0.00016008572,0.00012697405,0.00010817047],"domain_scores_gemma":[0.9989113,0.00086925377,0.00007357143,0.000066433655,0.000037912763,0.000041503907],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008815297,0.00007900079,0.00010809237,0.000053244006,0.000036691166,0.000019819978,0.000055608038,0.00004085863,0.000017959715],"category_scores_gemma":[0.004219563,0.00006576173,0.000008838985,0.00028577863,0.00011349481,0.00012793616,0.00003259568,0.00009244815,0.000011975356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006870873,0.000116570984,0.012846665,0.00012537399,0.000004910643,0.00004561482,0.0030622268,0.00036129233,0.96671015,0.00044481084,0.00026454512,0.0091469865],"study_design_scores_gemma":[0.0024874313,0.0012757113,0.120181225,0.00033250998,0.000012758393,0.000004801973,0.0006093495,0.0031136684,0.87059695,0.0006745597,0.0005008922,0.00021015362],"about_ca_topic_score_codex":0.0000033282474,"about_ca_topic_score_gemma":0.000004295519,"teacher_disagreement_score":0.107334554,"about_ca_system_score_codex":0.00000551671,"about_ca_system_score_gemma":0.000034397657,"threshold_uncertainty_score":0.5051516},"labels":[],"label_agreement":null},{"id":"W3106920291","doi":"10.1038/s41380-020-00951-9","title":"The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies","year":2020,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":306,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute for Health and Care Research","keywords":"Kynurenic acid; Quinolinic acid; Kynurenine; Kynurenine pathway; Major depressive disorder; Bipolar disorder; Schizophrenia (object-oriented programming); Psychology; Internal medicine; Mood disorders; Endocrinology; Pharmacology; Psychiatry; Mood; Medicine; Tryptophan; Chemistry; Biochemistry; Amino acid","score_opus":0.048264670604378834,"score_gpt":0.32075007426303637,"score_spread":0.27248540365865753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3106920291","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029365806,0.99658424,0.00013513275,0.0011014566,0.00030373543,0.0011757495,0.0002901946,0.00005580189,0.000060061724],"genre_scores_gemma":[0.000682455,0.9981207,0.00026579728,0.00028588987,0.000032993845,0.00039999594,0.000029436633,0.00010341201,0.00007927228],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9949468,0.0011981803,0.0012919336,0.0013900768,0.0006194802,0.00055356167],"domain_scores_gemma":[0.9970354,0.0007706844,0.0009054167,0.0010916758,0.00005086334,0.00014599758],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031590907,0.00090848154,0.0045264973,0.0006960422,0.0003064268,0.00010336491,0.0010856034,0.0002570488,0.000031886146],"category_scores_gemma":[0.0008321488,0.0005632053,0.003158306,0.003869732,0.0005502262,0.00008734539,0.0005097738,0.0007901736,0.000012029321],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016745759,0.00083877495,0.00013362184,0.010553743,0.1669055,0.00023814848,0.0004382797,0.0000726713,0.00019238763,0.01644253,0.00041015958,0.80360675],"study_design_scores_gemma":[0.0012998028,0.00014450835,0.000022697424,0.00041650966,0.12636688,0.00002253636,0.00024621026,0.0000484572,0.00009641197,0.0015166996,0.8688562,0.00096311094],"about_ca_topic_score_codex":0.00003869902,"about_ca_topic_score_gemma":0.0009857136,"teacher_disagreement_score":0.868446,"about_ca_system_score_codex":0.00002583549,"about_ca_system_score_gemma":0.0002710186,"threshold_uncertainty_score":0.99968195},"labels":[],"label_agreement":null},{"id":"W3108114145","doi":"10.1038/s41398-020-01095-8","title":"A randomised clinical trial of methotrexate points to possible efficacy and adaptive immune dysfunction in psychosis","year":2020,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo; Medical Research Council; Stanley Medical Research Institute","keywords":"Methotrexate; Medicine; Placebo; Psychosis; Internal medicine; Immune system; Immunology; Schizophrenia (object-oriented programming); Leukopenia; Clinical trial; Psychiatry; Chemotherapy; Pathology","score_opus":0.08077667333984238,"score_gpt":0.34987727252992334,"score_spread":0.26910059919008095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108114145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9754767,0.00015163307,0.003998938,0.016848225,0.00069996895,0.001255594,0.000026224012,0.000040531,0.001502221],"genre_scores_gemma":[0.9906725,0.000038493836,0.007017217,0.0020579614,0.00015332038,0.000025486932,0.0000034843965,0.000015684309,0.00001584839],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99810565,0.00034139573,0.0006835296,0.00044855586,0.0002607146,0.00016018846],"domain_scores_gemma":[0.9989948,0.0006039636,0.00012493225,0.00012154476,0.000019817628,0.00013493159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040368154,0.00013903018,0.00032550053,0.00011462813,0.000046222278,0.000014812187,0.00013911747,0.000088204906,0.000101774895],"category_scores_gemma":[0.00034992184,0.00013132075,0.00014841514,0.00054396206,0.00008766708,0.00011402982,0.000011919564,0.00019825308,0.000025208636],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9124276,0.0019793895,0.00488371,0.00007832845,0.00006982387,0.000003230646,0.0021507058,0.00048457005,0.037913177,0.010474396,0.00088646647,0.028648624],"study_design_scores_gemma":[0.71981305,0.0027762216,0.26066726,0.00010275236,0.000048798986,0.0000026150003,0.0001529597,0.0029665013,0.0026891779,0.009792133,0.00054955913,0.00043897956],"about_ca_topic_score_codex":0.0000094975085,"about_ca_topic_score_gemma":0.000015555073,"teacher_disagreement_score":0.25578356,"about_ca_system_score_codex":0.000003896459,"about_ca_system_score_gemma":0.00007275718,"threshold_uncertainty_score":0.5355105},"labels":[],"label_agreement":null},{"id":"W3108525610","doi":"10.1139/cjpp-2020-0398","title":"CF3-substituted diselenide modulatory effects on oxidative stress, induced by single and repeated morphine administrations, in susceptible tissues of mice","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Universidade Federal de Santa Maria; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Morphine; Oxidative stress; Chemistry; Pharmacology; Diphenyl diselenide; Superoxide dismutase; Kidney; Diselenide; Antioxidant; Glutathione; Endocrinology; Internal medicine; Medicine; Biochemistry; Selenium; Enzyme","score_opus":0.02580291250912581,"score_gpt":0.2699846916245298,"score_spread":0.244181779115404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108525610","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973786,0.00045310243,0.000002328535,0.0017767511,0.0001632159,0.0001289352,0.000054797314,0.0000042498928,0.000038042144],"genre_scores_gemma":[0.9981623,0.00009114375,0.000015250842,0.0016426683,0.00006629161,0.0000023979524,0.0000063893167,0.0000071084123,0.000006434773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990791,0.00025533605,0.00023497491,0.00019674061,0.000044797805,0.0001890197],"domain_scores_gemma":[0.9991599,0.00029218162,0.00017637723,0.000040885578,0.000033176704,0.0002975096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005394681,0.00011399354,0.00026086235,0.00012715247,0.0000677779,0.000006097359,0.0001179794,0.00008840983,0.00012257081],"category_scores_gemma":[0.0001972727,0.000107813634,0.000023980501,0.00017947367,0.00026607758,0.000102865975,0.0000113400065,0.00026295843,0.000001306888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014408324,0.00005286265,0.0006630369,0.000057755435,0.000018533405,0.00006822021,0.00050470274,0.000044688637,0.9968347,0.00009034074,0.0011878544,0.00033320815],"study_design_scores_gemma":[0.0011410197,0.0010214789,0.0057677585,0.000023903029,0.00001574331,0.000011148381,0.00006619377,0.000074099,0.9912342,0.00023542087,0.0003187363,0.00009033586],"about_ca_topic_score_codex":0.00021092803,"about_ca_topic_score_gemma":0.0006051865,"teacher_disagreement_score":0.005600551,"about_ca_system_score_codex":0.000022208817,"about_ca_system_score_gemma":0.00022521627,"threshold_uncertainty_score":0.43965125},"labels":[],"label_agreement":null},{"id":"W3108695684","doi":"10.1038/s41380-020-00952-8","title":"Behavioral, neuroanatomical, and molecular correlates of resilience and susceptibility to maternal immune activation","year":2020,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":135,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Medical Research Foundation; Medical Research Council; Universität Zürich; Research Councils UK; Government of the United Kingdom; Functional Genomics Center Zurich; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Centre for the Replacement, Refinement and Reduction of Animals in Research; King's College London; National Science Foundation","keywords":"Offspring; Prepulse inhibition; Immune system; Psychology; Cohort; Functional magnetic resonance imaging; Neuroscience; Immunology; Biology; Medicine; Internal medicine; Pregnancy; Schizophrenia (object-oriented programming); Genetics; Psychiatry","score_opus":0.012114015034123946,"score_gpt":0.258983071552801,"score_spread":0.24686905651867702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108695684","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943039,0.00019490925,0.0015365783,0.003440241,0.00009644626,0.00028440918,0.000008475483,0.00004709667,0.00008793726],"genre_scores_gemma":[0.996288,0.000017678132,0.00095523515,0.002698624,0.000008614325,0.0000060605053,0.0000011164061,0.00002048128,0.00000415932],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987091,0.000097944845,0.00024999017,0.00052889675,0.00021999268,0.00019412166],"domain_scores_gemma":[0.99945384,0.00002593413,0.000085358726,0.00023985484,0.000021272683,0.00017372191],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005612024,0.00015591324,0.00017793891,0.0000593,0.000062797844,0.00004525878,0.00019830134,0.00005599313,0.000021745816],"category_scores_gemma":[0.00015799691,0.00015875664,0.000050315535,0.00029329912,0.00017809993,0.000098518954,0.00014386259,0.00015286209,0.0000066601083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009765064,0.0000760164,0.013917796,0.00004403404,0.0000025088582,0.000010765853,0.00013967435,0.000036829773,0.98319006,0.0015858926,0.00005387127,0.000844898],"study_design_scores_gemma":[0.00054572365,0.00037922786,0.056985073,0.000031206215,0.000011727652,0.000013277828,0.00011932226,0.0004187653,0.94010985,0.0011205984,0.00006288728,0.00020236487],"about_ca_topic_score_codex":0.000028164464,"about_ca_topic_score_gemma":0.0000023221783,"teacher_disagreement_score":0.043080237,"about_ca_system_score_codex":0.000006366124,"about_ca_system_score_gemma":0.000031084623,"threshold_uncertainty_score":0.6473908},"labels":[],"label_agreement":null},{"id":"W3108811217","doi":"10.1017/pen.2020.14","title":"Personality traits in psychosis and psychosis risk linked to TSPO expression: a neuroimmune marker","year":2020,"lang":"en","type":"article","venue":"Personality Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Toronto; McMaster University; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health","keywords":"Translocator protein; Psychosis; Neuroticism; Psychology; Personality; Neuroinflammation; Microglia; Clinical psychology; Neuroscience; Internal medicine; Inflammation; Psychiatry; Medicine","score_opus":0.06241329713973956,"score_gpt":0.30413258773250157,"score_spread":0.241719290592762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108811217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97758454,0.00011899803,0.00041579772,0.019700756,0.00031875167,0.0006394427,0.00012912008,0.00017784552,0.0009147341],"genre_scores_gemma":[0.9612268,0.00021887322,0.00031139108,0.037894778,0.00008287923,0.00007759456,7.9007106e-7,0.000034987814,0.00015190316],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9949263,0.00070827804,0.00050305924,0.0021237056,0.0009197672,0.00081891246],"domain_scores_gemma":[0.99822456,0.00040064479,0.00017310932,0.00042198072,0.000036321904,0.00074341404],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000536617,0.0004270106,0.0004294014,0.00016342952,0.0004577906,0.00034000003,0.0009937537,0.000112184796,0.00017556464],"category_scores_gemma":[0.0033916098,0.00040891516,0.00016374957,0.002128671,0.0005840583,0.00069956767,0.00030112636,0.0006676715,0.00004699036],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003865051,0.00032760538,0.044827893,0.00006703191,0.000001247308,0.000042925207,0.005653748,0.000035591085,0.94161075,0.0001643243,0.0019786113,0.004903775],"study_design_scores_gemma":[0.0010416566,0.0002601792,0.9694888,0.00004928646,0.000006731737,0.000023549901,0.0002589549,0.0025113246,0.009489977,0.00015222309,0.016185282,0.0005320642],"about_ca_topic_score_codex":0.00023699718,"about_ca_topic_score_gemma":0.000058675887,"teacher_disagreement_score":0.93212074,"about_ca_system_score_codex":0.000033508146,"about_ca_system_score_gemma":0.000049418857,"threshold_uncertainty_score":0.99983627},"labels":[],"label_agreement":null},{"id":"W3109751528","doi":"10.1101/2020.12.03.406454","title":"Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioural, and transcriptional study","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; Montreal Neurological Institute and Hospital; University of Toronto; University Health Network; McGill University; Douglas Mental Health University Institute","funders":"McGill University","keywords":"Neuroscience; Neuroimaging; Hippocampus; Psychology; Striatum; Neurodevelopmental disorder; Ventral striatum; Internal medicine; Biology; Medicine; Autism; Developmental psychology","score_opus":0.03419428952420465,"score_gpt":0.25046424289361374,"score_spread":0.2162699533694091,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3109751528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967273,0.00001935996,0.00023284569,0.00057184463,0.00054902484,0.0012655257,0.0003772435,0.00025615632,7.046252e-7],"genre_scores_gemma":[0.99781597,0.000021681653,0.0010816033,0.00070768164,0.00006400265,0.00019478408,0.0000021473513,0.00010636275,0.0000057950333],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9966756,0.00034779526,0.0006277161,0.0013533215,0.0005554929,0.00044004957],"domain_scores_gemma":[0.99897856,0.000065162196,0.00022568565,0.0003273007,0.00012404064,0.00027924372],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021142286,0.00055702194,0.00042732715,0.00041109955,0.00018178242,0.0005126045,0.0005264575,0.00016122394,0.000047165115],"category_scores_gemma":[0.00021609709,0.00056504365,0.00005911211,0.0006965555,0.00012958802,0.0006081344,0.00020093434,0.00082396786,0.000010933232],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043001596,0.00038364675,0.06042286,0.000054209326,0.000016450194,0.00012952545,0.00067333045,0.00011019175,0.9376991,0.00006161978,0.0000097101265,0.000009366814],"study_design_scores_gemma":[0.001058472,0.00033014285,0.8319492,0.00010003586,0.000015405349,9.7574365e-8,0.00004835699,0.000121117024,0.1658487,0.0000015045567,0.00003880353,0.00048821114],"about_ca_topic_score_codex":0.0005676137,"about_ca_topic_score_gemma":0.000034973502,"teacher_disagreement_score":0.77185035,"about_ca_system_score_codex":0.0001572399,"about_ca_system_score_gemma":0.00038803107,"threshold_uncertainty_score":0.9996801},"labels":[],"label_agreement":null},{"id":"W3109972373","doi":"10.1016/j.mehy.2020.110420","title":"The first psychiatric pandemic: Encephalitis lethargica, 1917–27","year":2020,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Pandemic; Psychiatry; Depression (economics); Encephalitis; Coronavirus; Schizophrenia (object-oriented programming); Mania; Psychosis; Medicine; Disease; Psychology; Coronavirus disease 2019 (COVID-19); Virology; Virus; Bipolar disorder; Mood; Infectious disease (medical specialty); Pathology","score_opus":0.05195616942931905,"score_gpt":0.27315594085115585,"score_spread":0.2211997714218368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3109972373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5459109,0.0048137093,0.0010483079,0.36645937,0.0027586273,0.00093920936,0.00006553136,0.0011943185,0.07681003],"genre_scores_gemma":[0.9590409,0.0018721364,0.000043728563,0.037689175,0.00050737965,0.000023701932,6.9968394e-7,0.000023808027,0.00079851726],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978074,0.00014898613,0.00027574084,0.0004381017,0.0008849716,0.00044482568],"domain_scores_gemma":[0.99720377,0.0020782468,0.00006883394,0.0002441913,0.000012939223,0.0003920251],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00023808205,0.0001654042,0.00017522024,0.000026134241,0.0004141576,0.000086790315,0.0009406094,0.000112895694,0.0016329996],"category_scores_gemma":[0.007574129,0.00010017659,0.000118601456,0.0004741613,0.00058650575,0.000082778315,0.00013246207,0.00037059048,0.000879399],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045084677,0.0006980732,0.025490763,0.00022821344,0.00005317137,0.00057851296,0.0042204987,0.000012826383,0.009244581,0.05164084,0.4574211,0.4499606],"study_design_scores_gemma":[0.00060246635,0.00011353791,0.0020843802,0.000017888524,0.0000052640344,0.000039081464,0.00019003049,0.000315093,0.0026859276,0.0024087392,0.99133563,0.00020193933],"about_ca_topic_score_codex":0.000018152074,"about_ca_topic_score_gemma":0.000040355375,"teacher_disagreement_score":0.53391457,"about_ca_system_score_codex":0.0000121239755,"about_ca_system_score_gemma":0.000093255745,"threshold_uncertainty_score":0.99989855},"labels":[],"label_agreement":null},{"id":"W3110218337","doi":"10.1093/cdn/nzaa156","title":"Nonesterified Fatty Acids and Depression in Cancer Patients and Caregivers","year":2020,"lang":"en","type":"article","venue":"Current Developments in Nutrition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vector Institute; Queen's University; Institute of Cancer Research; Ontario Institute for Cancer Research; University of Toronto; Princess Margaret Cancer Centre","funders":"","keywords":"Depression (economics); Medicine; Internal medicine; Cancer; Psychiatry; Gerontology; Psychology; Endocrinology; Oncology; Economics; Keynesian economics","score_opus":0.04457742095760483,"score_gpt":0.28919762563573126,"score_spread":0.24462020467812642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110218337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99867964,0.00047806802,0.000016835189,0.00013370052,0.00025432205,0.00033055022,0.000013616109,0.00001871281,0.00007453974],"genre_scores_gemma":[0.99745,0.0021354195,0.000086974345,0.00022506536,0.000014162592,0.00006733567,0.000012658023,0.0000067464507,0.0000016294199],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991606,0.00004578912,0.00015655071,0.00034135132,0.00013729549,0.00015839821],"domain_scores_gemma":[0.9998165,0.000025993708,0.00003947581,0.00003450651,0.00001318689,0.00007036067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000025741107,0.0001041001,0.00010679265,0.00009636341,0.00004482709,0.000026693386,0.000068475034,0.0000423576,0.000006532267],"category_scores_gemma":[0.00009492962,0.00010575253,0.000007946503,0.00024513187,0.000045552155,0.00020176887,0.00007795989,0.00011188474,0.0000024197093],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012536156,0.00029587108,0.9150359,0.00033295623,0.0000010027819,0.000006115352,0.0032324267,0.0000015662158,0.011066667,0.000016687856,0.00022228909,0.06966317],"study_design_scores_gemma":[0.004480715,0.000026688082,0.96292526,0.00043870552,0.0000014164417,5.743405e-7,0.00023647695,0.00009496246,0.029235482,0.00008501707,0.00226152,0.0002131744],"about_ca_topic_score_codex":0.000006151572,"about_ca_topic_score_gemma":0.000012506869,"teacher_disagreement_score":0.06945,"about_ca_system_score_codex":0.000047849404,"about_ca_system_score_gemma":0.00001930766,"threshold_uncertainty_score":0.43124628},"labels":[],"label_agreement":null},{"id":"W3110756294","doi":"10.1016/j.bbih.2020.100191","title":"Sex-dependent role of CD300f immune receptor in generalized anxiety disorder","year":2020,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Comisión Sectorial de Investigación Científica; International Society for Neurochemistry; Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Institut Pasteur de Montevideo; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Langley Research Center; International Brain Research Organization; Agencia Nacional de Investigación e Innovación; International Center for Genetic Engineering and Biotechnology","keywords":"Anxiety; Generalized anxiety disorder; Immune system; Open field; Population; Receptor; Psychology; Synaptic pruning; Elevated plus maze; Immunology; Medicine; Neuroscience; Biology; Microglia; Internal medicine; Psychiatry; Inflammation","score_opus":0.03473978999620336,"score_gpt":0.2992241829779604,"score_spread":0.264484392981757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110756294","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98983055,0.0010352406,0.000043858843,0.0071703247,0.00016743237,0.0011040022,0.00017280866,0.000161466,0.00031429366],"genre_scores_gemma":[0.9930258,0.0007457682,0.00033030479,0.0053011617,0.000038537382,0.00010003632,0.000054062446,0.000062613486,0.00034172798],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960523,0.0011801482,0.00092758576,0.0005979309,0.0005130937,0.0007289448],"domain_scores_gemma":[0.9983944,0.00021517977,0.00035853303,0.0006829778,0.000037423044,0.00031147484],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00066597987,0.00033453113,0.00066053733,0.00016350432,0.00027301555,0.000041921758,0.00083233236,0.00015780953,0.00054293283],"category_scores_gemma":[0.0005362019,0.00034983538,0.00019294725,0.0008165783,0.00021618999,0.00022673904,0.00030607334,0.00074096426,0.000068860754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018169318,0.0011733612,0.012755542,0.000097109754,0.0000044631474,0.000004983835,0.007221392,0.000030951618,0.9313879,0.00070698763,0.00046210302,0.045973483],"study_design_scores_gemma":[0.011866921,0.0016536482,0.2238322,0.00015476714,0.000023453043,0.000032978078,0.012451796,0.00062736653,0.7082266,0.0003127075,0.039230254,0.001587264],"about_ca_topic_score_codex":0.004262169,"about_ca_topic_score_gemma":0.0003649399,"teacher_disagreement_score":0.22316128,"about_ca_system_score_codex":0.00013087806,"about_ca_system_score_gemma":0.00034603817,"threshold_uncertainty_score":0.9998954},"labels":[],"label_agreement":null},{"id":"W3111036614","doi":"10.1093/brain/awaa405","title":"Depression, dementia and immune dysregulation","year":2020,"lang":"en","type":"article","venue":"Brain","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":180,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Carleton University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Dementia; Depression (economics); Medicine; Disease; Antidepressant; Cognitive decline; Proinflammatory cytokine; Immune dysregulation; Stroke (engine); Chronic stress; Psychology; Neuroscience; Inflammation; Psychiatry; Immunology; Internal medicine; Anxiety","score_opus":0.021433550575665188,"score_gpt":0.2424141932091069,"score_spread":0.22098064263344172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111036614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97708184,0.00043460252,0.0016567756,0.015351447,0.00007233204,0.00016553338,0.000003811578,0.00013289494,0.0051007885],"genre_scores_gemma":[0.99383235,0.00000675829,0.00014489051,0.0058402056,0.00003215661,0.0000032038506,0.0000014809284,0.0000072024663,0.0001317398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994973,0.00004241234,0.00008247585,0.00019253371,0.00008802964,0.000097243545],"domain_scores_gemma":[0.999768,0.000071752605,0.000027424949,0.000071941075,0.000004077133,0.00005679949],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000035921577,0.000053925167,0.000053076394,0.000016039256,0.000071765935,0.00002918233,0.000075499825,0.000023302033,0.00013166509],"category_scores_gemma":[0.0003748323,0.00004899011,0.000016535549,0.00011272036,0.000040946332,0.000092045775,0.000053529704,0.000040842,0.000044700068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016929936,0.000011878938,0.0010493022,0.000009298537,0.0000019056777,0.0000034659706,0.00034492434,0.000009710694,0.9703624,0.0022964652,0.0048578246,0.021035884],"study_design_scores_gemma":[0.0012759881,0.000060497387,0.1939532,0.000014057601,0.000005971913,0.000007904891,0.000111819456,0.003760165,0.75655615,0.002931267,0.041095622,0.00022735332],"about_ca_topic_score_codex":0.000002442454,"about_ca_topic_score_gemma":0.0000010011493,"teacher_disagreement_score":0.21380626,"about_ca_system_score_codex":0.000001860825,"about_ca_system_score_gemma":0.000006397755,"threshold_uncertainty_score":0.19977586},"labels":[],"label_agreement":null},{"id":"W3111076277","doi":"10.1007/978-3-030-57231-0_18","title":"TSPO Imaging in Psychiatric Disorders","year":2020,"lang":"en","type":"book-chapter","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Translocator protein; Major depressive disorder; Schizophrenia (object-oriented programming); Biomarker; Psychology; Positron emission tomography; Psychosis; Medicine; Psychiatry; Neuroscience; Internal medicine; Clinical psychology; Cognition; Microglia; Chemistry; Biochemistry","score_opus":0.016870309434286107,"score_gpt":0.23677048732365116,"score_spread":0.21990017788936506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111076277","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006567994,0.0003657021,0.0000962768,0.0046936707,0.0004118673,0.00030646846,0.000012524535,0.00020571041,0.9938421],"genre_scores_gemma":[0.1861733,0.0016541,0.00033443788,0.018452631,0.0002915076,0.000018923105,0.000015539355,0.00023512209,0.79282445],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99835074,0.000018105606,0.00030351535,0.00075884187,0.0002833396,0.00028546245],"domain_scores_gemma":[0.99941087,0.00009589687,0.00010115429,0.00028361895,0.0000058271075,0.000102663675],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000038926995,0.00033640282,0.00026824087,0.0003144898,0.000056280256,0.00005072936,0.00042232664,0.00012469894,0.0017545973],"category_scores_gemma":[0.0000758259,0.00032343922,0.00017152808,0.00013225932,0.00011802113,0.00009782247,0.00011705927,0.00046333,0.0011748763],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004527027,0.00006120723,0.0003136646,0.000077517754,0.0000041545877,0.000087345856,0.00015643402,0.000009158302,0.0012007209,0.9099301,0.027553821,0.060560595],"study_design_scores_gemma":[0.001116625,0.00005544446,0.00040013163,0.00005369872,0.000011361712,0.000010228873,0.000054680244,0.00029033676,0.00035911173,0.25338557,0.7432157,0.0010471388],"about_ca_topic_score_codex":0.00001951055,"about_ca_topic_score_gemma":0.00013251626,"teacher_disagreement_score":0.7156618,"about_ca_system_score_codex":0.00003301678,"about_ca_system_score_gemma":0.00006390365,"threshold_uncertainty_score":0.99992174},"labels":[],"label_agreement":null},{"id":"W3111518528","doi":"10.1177/1178646920977013","title":"Alteration in Gene Pair Correlations in Tryptophan Metabolism as a Hallmark in Cancer Diagnosis","year":2020,"lang":"en","type":"article","venue":"International Journal of Tryptophan Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Gene; Cancer; Biology; Tryptophan Metabolism; Tryptophan; Metabolic pathway; Enzyme; Genetics; Biochemistry; Amino acid","score_opus":0.13841043597469144,"score_gpt":0.41826889180231414,"score_spread":0.2798584558276227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111518528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97404575,0.0008640355,0.00011759098,0.02329015,0.0006126377,0.00032776204,0.000029341263,0.000011828609,0.000700894],"genre_scores_gemma":[0.99617213,0.0013997945,0.0002275902,0.001457307,0.00048310834,0.00013041256,0.0000043916116,0.00002546274,0.00009980638],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9958241,0.00076135213,0.0009225424,0.000411752,0.0016193531,0.00046091556],"domain_scores_gemma":[0.9981748,0.00090510835,0.00022949663,0.0001328836,0.000345152,0.00021258547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009538726,0.00017894736,0.0003341646,0.0015521739,0.000059635047,0.00017124723,0.0010372676,0.00012225531,0.0007213771],"category_scores_gemma":[0.0035546464,0.0001738697,0.00013058432,0.0015854362,0.00013621344,0.00072075817,0.00016745688,0.0011283099,0.00006266901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0049369456,0.0042124633,0.2968532,0.00009587834,0.00013164878,0.0072039412,0.020391956,0.026666151,0.5437533,0.020547422,0.007890367,0.06731667],"study_design_scores_gemma":[0.014422356,0.00062566245,0.38662353,0.00068158767,0.000008566507,0.00016399013,0.0016891885,0.016266113,0.54961324,0.014759241,0.014473562,0.0006729486],"about_ca_topic_score_codex":0.0004838069,"about_ca_topic_score_gemma":0.0006375855,"teacher_disagreement_score":0.089770295,"about_ca_system_score_codex":0.00038493014,"about_ca_system_score_gemma":0.00045053297,"threshold_uncertainty_score":0.7898573},"labels":[],"label_agreement":null},{"id":"W3111586991","doi":"10.1002/alz.042269","title":"Biomarkers of agitation in moderate‐to‐severe Alzheimer's disease patients enrolled in an RCT with nabilone","year":2020,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Baycrest Hospital; Toronto Rehabilitation Institute; Sunnybrook Health Science Centre; Occupational Cancer Research Centre; Sunnybrook Hospital; University of Toronto","funders":"","keywords":"Biomarker; Internal medicine; Placebo; Medicine; Randomized controlled trial; Metabolite; Gastroenterology; Psychology; Chemistry; Pathology","score_opus":0.03266657739623738,"score_gpt":0.26228111154346484,"score_spread":0.22961453414722746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111586991","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99619406,0.0014870171,0.000050758423,0.00093964784,0.000063509244,0.0009571282,0.000029698449,0.000042550193,0.00023563737],"genre_scores_gemma":[0.9968673,0.000008517271,0.00047911302,0.0025008684,0.000010771288,0.00006933566,0.000030966137,0.000032513886,5.9127535e-7],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99809724,0.00019271269,0.00039353062,0.00060043554,0.00038107124,0.00033500104],"domain_scores_gemma":[0.9992236,0.000061319,0.00012386982,0.00024545428,0.00007148444,0.0002743016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008671779,0.00021995507,0.00024381289,0.00020132215,0.000050256367,0.00004291847,0.00029520702,0.000044041386,0.00008456962],"category_scores_gemma":[0.00013679189,0.00020503407,0.000047242,0.0008591709,0.00008466592,0.00047430155,0.00007673368,0.00009968205,0.00003167946],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018598264,0.0052860426,0.8041129,0.000069023205,0.0031399655,0.00020216651,0.012420331,0.013342732,0.0629104,0.0007419715,0.002463566,0.07671265],"study_design_scores_gemma":[0.0143207405,0.0016230256,0.85863835,0.00009849283,0.00181201,8.684887e-7,0.00070432073,0.010946781,0.10977629,0.00058646884,0.00028599845,0.0012066402],"about_ca_topic_score_codex":0.000070149355,"about_ca_topic_score_gemma":0.00015794577,"teacher_disagreement_score":0.07550601,"about_ca_system_score_codex":0.0000058071464,"about_ca_system_score_gemma":0.00007792921,"threshold_uncertainty_score":0.8361047},"labels":[],"label_agreement":null},{"id":"W3112363919","doi":"10.1007/s11920-020-01206-8","title":"Using Precision Medicine with a Neurodevelopmental Perspective to Study Inflammation and Depression","year":2020,"lang":"en","type":"review","venue":"Current Psychiatry Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Public Health Ontario; Toronto Metropolitan University; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Depression (economics); Mood; Inflammation; Perspective (graphical); Medicine; Pregnancy; Precision medicine; Neurodevelopmental disorder; Psychology; Bioinformatics; Neuroscience; Clinical psychology; Psychiatry; Immunology; Autism; Biology; Pathology; Computer science","score_opus":0.09442270280719754,"score_gpt":0.3926538686278983,"score_spread":0.29823116582070075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112363919","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012268186,0.98023427,0.0003077201,0.0001140151,0.0031756253,0.0035360088,0.0000050285353,0.00011840871,0.00024073498],"genre_scores_gemma":[0.0050800727,0.99305606,0.0007332513,0.00006430039,0.0007645991,0.00016222194,0.000014499221,0.00010797521,0.000017048293],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966649,0.00025161318,0.00079990027,0.0014149016,0.000623707,0.00024500824],"domain_scores_gemma":[0.99846756,0.00007418115,0.0007358273,0.00041684735,0.00005767385,0.00024788728],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017905983,0.0005068875,0.000951988,0.00029368413,0.00022418034,0.00006271833,0.00018106327,0.000082927014,0.000025350535],"category_scores_gemma":[0.00053642545,0.00034003434,0.00008882977,0.00083969673,0.000070577975,0.00016133924,0.00023059986,0.0004148833,0.000007110798],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041063464,0.00023287411,0.0009571508,0.001560587,0.00002589223,0.00021586502,0.0016169352,0.0000024881701,0.00004038205,0.000030123501,0.00025769972,0.99501896],"study_design_scores_gemma":[0.0018373783,0.0013976354,0.0024918779,0.042907767,0.0011406548,0.005265767,0.003126326,0.00006148883,0.00006036776,0.00062181684,0.9389373,0.0021516406],"about_ca_topic_score_codex":0.0000053268695,"about_ca_topic_score_gemma":0.0000060176803,"teacher_disagreement_score":0.9928673,"about_ca_system_score_codex":0.00010293361,"about_ca_system_score_gemma":0.0003682568,"threshold_uncertainty_score":0.99990517},"labels":[],"label_agreement":null},{"id":"W3112880362","doi":"10.3389/fpsyt.2020.594766","title":"The Relationship Between Serum Cytokine Levels and the Degree of Psychosis and Cognitive Impairment in Patients With Methamphetamine-Associated Psychosis in Chinese Patients","year":2020,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Psychosis; Methamphetamine; Positive and Negative Syndrome Scale; Internal medicine; Schizophrenia (object-oriented programming); Psychology; Cognition; Medicine; Cytokine; Interleukin; Psychiatry; Clinical psychology","score_opus":0.025900866286629836,"score_gpt":0.25429943415428,"score_spread":0.2283985678676502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112880362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948601,0.0002958074,0.000084695675,0.0028389492,0.0005210286,0.0010917133,0.00016806231,0.000014801279,0.0001248484],"genre_scores_gemma":[0.9988011,0.000038807997,0.00032291716,0.000720274,0.000016732496,0.000058434103,0.00001028694,0.000023708424,0.00000770499],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99787146,0.0004884688,0.00050801184,0.0004645159,0.00034765212,0.00031989423],"domain_scores_gemma":[0.99866664,0.00076652464,0.00026959498,0.00018060116,0.00003463984,0.000081966864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036696068,0.00024037772,0.00037911357,0.00017871798,0.00013553575,0.000036061494,0.00025895273,0.00010479222,0.0000023881548],"category_scores_gemma":[0.0009885116,0.00014513603,0.000049876086,0.0012975532,0.00040397522,0.00016990757,0.00007111511,0.00037035052,6.6075455e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009566193,0.00027901752,0.99375457,0.000026069127,0.000024121695,2.4124654e-7,0.0018144626,0.0000028768654,9.0627213e-7,0.000055554563,0.0005713905,0.0025142024],"study_design_scores_gemma":[0.016330117,0.00029746036,0.9792511,0.00013378232,0.000020311058,7.80229e-8,0.0006337614,0.00007879811,0.000010753296,0.003063328,0.00000787633,0.00017266581],"about_ca_topic_score_codex":0.00004807638,"about_ca_topic_score_gemma":0.00038917866,"teacher_disagreement_score":0.015373497,"about_ca_system_score_codex":0.000035948484,"about_ca_system_score_gemma":0.000027784974,"threshold_uncertainty_score":0.59184754},"labels":[],"label_agreement":null},{"id":"W3118035874","doi":"10.1096/fasebj.2018.32.1_supplement.877.10","title":"Antigen‐Induced Arthritis in Mice induces Depression‐Like Behavior and Microglial Activation in Hippocampus after the Resolution of Peripheral Inflammation","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Inflammation; Arthritis; Depression (economics); Rheumatoid arthritis; Immunology; Internal medicine; Antigen","score_opus":0.019415993726416187,"score_gpt":0.25666380429947994,"score_spread":0.23724781057306374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118035874","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99895626,0.000110780005,0.000030541374,0.00041017286,0.00021162849,0.00021890624,0.000002420639,0.000006425263,0.00005288093],"genre_scores_gemma":[0.9994605,0.00012790579,0.00003737962,0.00018529092,0.00015610103,0.000014595828,4.886186e-7,0.00000767503,0.000010069636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988637,0.0003272046,0.00028196367,0.00014304635,0.00020095703,0.0001831468],"domain_scores_gemma":[0.9995577,0.00009240149,0.00017742536,0.000107731496,0.00003475211,0.000030004887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040602885,0.000091580325,0.000097718344,0.000115929055,0.00019422031,0.00007095305,0.00017093365,0.00006704312,0.000038569415],"category_scores_gemma":[0.00015730424,0.000057951398,0.000029188172,0.00022137904,0.0002138567,0.00034500164,0.00004640573,0.00030855477,0.0000025715945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023871251,0.00003430059,0.0075494708,0.000001929531,0.0000010535475,0.000006543979,0.002691871,0.0000052461487,0.95858365,0.000009617657,0.000009262181,0.030868368],"study_design_scores_gemma":[0.0007065301,0.000058809976,0.2590706,0.00007937143,0.0000016828951,0.00008549095,0.0004912379,0.0000953594,0.73898983,0.0003456662,0.000015075748,0.000060340837],"about_ca_topic_score_codex":0.000071030634,"about_ca_topic_score_gemma":0.00032996043,"teacher_disagreement_score":0.25152114,"about_ca_system_score_codex":0.000036542264,"about_ca_system_score_gemma":0.000049584796,"threshold_uncertainty_score":0.23631893},"labels":[],"label_agreement":null},{"id":"W3119462853","doi":"10.1016/j.bbih.2021.100199","title":"The role of dopamine receptors in lymphocytes and their changes in schizophrenia","year":2021,"lang":"en","type":"review","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"European Regional Development Fund; Xunta de Galicia; Axencia Galega de Innovación; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad","keywords":"Dopaminergic; Dopamine; Neuroscience; Dopamine receptor; Crosstalk; Immune system; Receptor; Central nervous system; Schizophrenia (object-oriented programming); Dopamine receptor D2; Dopamine receptor D3; Biology; Nervous system; Medicine; Immunology; Internal medicine; Psychiatry","score_opus":0.05182393347043073,"score_gpt":0.33521513103559497,"score_spread":0.28339119756516423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3119462853","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.033068914,0.9648649,2.7683134e-7,0.0003666901,0.00021835425,0.0013122148,0.00008342351,0.000036828933,0.000048361195],"genre_scores_gemma":[0.0030660287,0.9961467,0.000024632443,0.00021503518,0.000029808465,0.00026587016,0.00005499844,0.00006541207,0.00013156011],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950374,0.0025917669,0.0009123328,0.000565118,0.00023975097,0.0006536355],"domain_scores_gemma":[0.9961395,0.0023264093,0.00056725554,0.0008088255,0.000025865646,0.0001321337],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012969603,0.00049423444,0.0016249439,0.0004516082,0.00029788868,0.00007366678,0.0007868632,0.0002617722,0.00003142929],"category_scores_gemma":[0.0009314761,0.0003509989,0.00018944571,0.0013595767,0.00040684984,0.00008347644,0.00038815354,0.00090511364,0.0000044302174],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015117839,0.00022724342,0.00006263095,0.0011329744,0.000003100969,0.0000045144516,0.00061128504,6.371569e-8,0.00017286977,0.00018764498,0.000033678047,0.9975489],"study_design_scores_gemma":[0.000974874,0.00020387955,0.0008664907,0.0072820126,0.00001622739,0.000065786895,0.0021939182,0.0000028017346,0.00086091936,0.000054829197,0.9870219,0.00045631046],"about_ca_topic_score_codex":0.0019454164,"about_ca_topic_score_gemma":0.0061626835,"teacher_disagreement_score":0.99709255,"about_ca_system_score_codex":0.0003066553,"about_ca_system_score_gemma":0.0011454558,"threshold_uncertainty_score":0.9998942},"labels":[],"label_agreement":null},{"id":"W3119693776","doi":"10.1016/j.bbr.2020.113101","title":"Roles of inflammation in intrinsic pathophysiology and antipsychotic drug-induced metabolic disturbances of schizophrenia","year":2021,"lang":"en","type":"review","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Diabetes Canada; University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Aging; Centre for Addiction and Mental Health; National Institutes of Health; University of Toronto; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Banting and Best Diabetes Centre, University of Toronto; U.S. Department of Defense","keywords":"Schizophrenia (object-oriented programming); Antipsychotic; Psychosis; Disease; Inflammation; Medicine; Psychiatry; Systemic inflammation; Metabolic syndrome; Management of schizophrenia; Antipsychotic drug; Mechanism (biology); Psychology; Neuroscience; Bioinformatics; Internal medicine; Obesity; Biology","score_opus":0.14486410609969597,"score_gpt":0.4077791471116648,"score_spread":0.26291504101196883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3119693776","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42054483,0.57861257,1.7321723e-7,0.00008462919,0.00007384589,0.0006071033,0.000036565372,0.000009904049,0.000030362886],"genre_scores_gemma":[0.18950036,0.8101808,0.00003074501,0.000009650447,0.00004668733,0.00009389195,0.000031587864,0.000033431254,0.00007286309],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9945811,0.0025445851,0.00092027575,0.0007647741,0.0006726225,0.00051663653],"domain_scores_gemma":[0.9970151,0.0018568125,0.0003771872,0.0005210898,0.00013336567,0.00009641255],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001027602,0.00032597833,0.001680107,0.0010036892,0.00008362366,0.000046386736,0.00061790517,0.00026703326,0.000030551833],"category_scores_gemma":[0.0019771059,0.00026753644,0.00025814478,0.0019643896,0.0006043312,0.00015100319,0.00034360905,0.00092341343,0.0000076207693],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041548985,0.00013231653,0.00016172198,0.0028321475,0.0000108597105,0.000036576832,0.00024002783,1.4004667e-7,0.022747707,0.0022194122,0.00006602829,0.9715115],"study_design_scores_gemma":[0.02174723,0.0031567416,0.22624288,0.1374095,0.0011280959,0.00042512984,0.0054408903,0.00009819844,0.3141681,0.013665771,0.26764828,0.008869209],"about_ca_topic_score_codex":0.00013817872,"about_ca_topic_score_gemma":0.00025162226,"teacher_disagreement_score":0.9626423,"about_ca_system_score_codex":0.00003308037,"about_ca_system_score_gemma":0.0003602734,"threshold_uncertainty_score":0.9999777},"labels":[],"label_agreement":null},{"id":"W3119985744","doi":"10.1016/j.bbi.2020.12.030","title":"Altered circadian rhythms in a mouse model of neurodevelopmental disorders based on prenatal maternal immune activation","year":2021,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Velux Stiftung","keywords":"Offspring; Circadian rhythm; Internal medicine; Endocrinology; Neurodevelopmental disorder; Rhythm; Locomotor activity; Period (music); Autism; Pregnancy; Psychology; Biology; Medicine; Developmental psychology; Genetics","score_opus":0.026735088019521087,"score_gpt":0.2558200552170359,"score_spread":0.22908496719751478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3119985744","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988487,0.0000087783465,0.00014327106,0.0002567474,0.000069430294,0.00024741623,0.000072715055,0.00003110368,0.0003218397],"genre_scores_gemma":[0.9990129,0.000021893551,0.00016773201,0.0004588465,0.000004801055,0.000037051057,0.00003348226,0.000021359505,0.0002419258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877465,0.000194651,0.00027719606,0.00030532377,0.00020946257,0.00023874117],"domain_scores_gemma":[0.9994203,0.0001257905,0.00008568593,0.0002899748,0.000017909135,0.00006033904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011302189,0.00016627184,0.00018109826,0.00015983157,0.00012080545,0.00004071059,0.00016460978,0.00007138022,0.00005382142],"category_scores_gemma":[0.00021943847,0.00017672688,0.000059258982,0.00022933625,0.00012977945,0.00021343053,0.000090524634,0.0002699188,0.0000022651811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011330372,0.000556053,0.0067349384,0.00003056226,0.0000012675317,0.000005876199,0.0005164261,0.00040213612,0.98314357,0.000108530185,0.0000073379606,0.008379999],"study_design_scores_gemma":[0.0012921809,0.00006021338,0.34582874,0.00003731964,0.0000021208668,0.000004651162,0.00013735496,0.004959356,0.647464,0.000057602596,0.000007673815,0.00014878303],"about_ca_topic_score_codex":0.00019115422,"about_ca_topic_score_gemma":0.00006705245,"teacher_disagreement_score":0.3390938,"about_ca_system_score_codex":0.000036086898,"about_ca_system_score_gemma":0.00010147439,"threshold_uncertainty_score":0.7206713},"labels":[],"label_agreement":null},{"id":"W3120278307","doi":"10.1080/25787489.2020.1866846","title":"Impact of extended-release niacin on immune activation in HIV-infected immunological non-responders on effective antiretroviral therapy","year":2020,"lang":"en","type":"article","venue":"HIV Research & Clinical Practice","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; HIV Legal Network; McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"Niacin; Kynurenine; Medicine; Immune system; CD8; Immunology; Internal medicine; Immune dysregulation; T cell; Viral load; Inflammation; Immunosenescence; Human immunodeficiency virus (HIV); Biology; Tryptophan","score_opus":0.15917333402475858,"score_gpt":0.4838689486746051,"score_spread":0.32469561464984653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120278307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98693216,0.00004486334,0.0001608053,0.006187791,0.00008689543,0.0015511842,0.00002205456,0.000085630345,0.004928644],"genre_scores_gemma":[0.9972806,0.000509277,0.000085836065,0.0018181221,0.00011624123,0.000062273175,0.000011545007,0.000041427007,0.000074680465],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.988448,0.007534182,0.0008766511,0.0010646266,0.0012946912,0.00078180607],"domain_scores_gemma":[0.9602303,0.038226206,0.00038832249,0.0006178976,0.00024219883,0.00029506165],"candidate_categories":["metaresearch","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0036214562,0.00031840094,0.00060175866,0.0003981469,0.0002016702,0.00009741249,0.00068146683,0.00033043217,0.0002675429],"category_scores_gemma":[0.13798414,0.0002419544,0.00040366716,0.0021637476,0.0008000261,0.0007099219,0.00020642477,0.00342136,0.00070048263],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.082656056,0.0077079744,0.0054667895,0.000028211525,0.00008636012,0.00020197935,0.00061802333,0.00016691082,0.81032026,0.0009125102,0.0022902696,0.08954465],"study_design_scores_gemma":[0.009819295,0.031197902,0.8611482,0.00012615687,0.0000071499644,0.0000041530843,0.0005190882,0.0020513085,0.09318112,0.00032061242,0.0012355873,0.0003894519],"about_ca_topic_score_codex":0.00016798459,"about_ca_topic_score_gemma":0.0000012487932,"teacher_disagreement_score":0.85568136,"about_ca_system_score_codex":0.0002054634,"about_ca_system_score_gemma":0.0003634437,"threshold_uncertainty_score":0.99887776},"labels":[],"label_agreement":null},{"id":"W3120679015","doi":"10.1016/j.biopsych.2020.12.025","title":"Large-Scale Transcriptomics Studies Provide Insight Into Sex Differences in Depression","year":2021,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":100,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Campbell Family Mental Health Research Institute; Brain and Behavior Research Foundation","keywords":"Major depressive disorder; Sex characteristics; Vulnerability (computing); Depression (economics); Psychology; Antidepressant; Psychological resilience; Clinical psychology; Developmental psychology; Psychiatry; Medicine; Anxiety; Internal medicine","score_opus":0.12321746322621534,"score_gpt":0.358280152156498,"score_spread":0.23506268893028265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120679015","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00373259,0.9927702,0.000029396637,0.00013668892,0.0017159806,0.0007319976,0.000043253593,0.00012372826,0.00071617385],"genre_scores_gemma":[0.0020179315,0.9961813,0.00037985318,0.0007825899,0.0002270759,0.00018157114,0.00003065672,0.000030199448,0.00016878429],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962759,0.00085582945,0.0007927303,0.0013136821,0.00022688601,0.00053497456],"domain_scores_gemma":[0.99873596,0.00047046412,0.00024110274,0.0004188744,0.000017869676,0.00011570979],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002032461,0.0005935897,0.0019725056,0.0001726254,0.00017711989,0.000060248924,0.00071367575,0.0007008849,0.000068274894],"category_scores_gemma":[0.0004602373,0.00034678946,0.00055206445,0.00066699664,0.0002753818,0.00007827703,0.00025097767,0.0007764978,0.000042509433],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046855574,0.0018436715,0.0054646353,0.011257284,0.00009229588,0.00006829772,0.0021254162,2.499594e-7,0.00019729603,0.002526338,0.0024886727,0.973889],"study_design_scores_gemma":[0.0004413675,0.0001201606,0.000248273,0.0055404096,0.00004490581,0.00001589025,0.00078728376,0.0000031514637,0.000029007615,0.0019815892,0.99015576,0.00063220423],"about_ca_topic_score_codex":0.0000034961413,"about_ca_topic_score_gemma":0.0000996614,"teacher_disagreement_score":0.9876671,"about_ca_system_score_codex":0.00006350953,"about_ca_system_score_gemma":0.00021062307,"threshold_uncertainty_score":0.99989843},"labels":[],"label_agreement":null},{"id":"W3121164713","doi":"10.20944/preprints201907.0293.v1","title":"Increased Serum Immunoglobulin Responses to Gut Commensal Gram-Negative Bacteria in Unipolar Major Depression and Bipolar Disorder Type 1, Especially When Melancholia is Present","year":2019,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Dysbiosis; Immunology; Gut–brain axis; Bipolar disorder; Major depressive disorder; Gut flora; Immunoglobulin A; Medicine; Internal medicine; Antibody; Immunoglobulin G","score_opus":0.0695769265120294,"score_gpt":0.33028903186060654,"score_spread":0.26071210534857714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3121164713","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921283,0.00070223724,0.00003497759,0.0021644544,0.00091272616,0.0025272095,0.00045126112,0.00019191754,0.00088692555],"genre_scores_gemma":[0.99495727,0.00060688274,0.00041160954,0.0017673904,0.00014220842,0.00015477836,0.0000391087,0.00012053094,0.0018002421],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99383414,0.0014892704,0.0008603544,0.0022748958,0.00068851805,0.0008528137],"domain_scores_gemma":[0.99621254,0.00076015724,0.0004240748,0.0020933987,0.00015185993,0.00035796824],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00082628464,0.0008067666,0.000899819,0.00057470513,0.00022666207,0.00018163137,0.0015172045,0.0006195116,0.0016307504],"category_scores_gemma":[0.0026188348,0.00080316263,0.00018060411,0.00050359,0.00026461785,0.0002913731,0.0053450484,0.0014425454,0.0012548746],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002620523,0.0004101381,0.7385751,0.00018465503,0.00006138679,0.00003898129,0.0044461037,0.00006477016,0.25172684,0.000066637855,0.00043601278,0.0013688682],"study_design_scores_gemma":[0.0017713795,0.000079279926,0.80507946,0.0003701953,0.0000285723,0.0000094102215,0.00016552076,0.00011016389,0.16185935,0.0016309709,0.028113892,0.000781808],"about_ca_topic_score_codex":0.0028996142,"about_ca_topic_score_gemma":0.00033759573,"teacher_disagreement_score":0.08986751,"about_ca_system_score_codex":0.0002186829,"about_ca_system_score_gemma":0.00038498253,"threshold_uncertainty_score":0.99952275},"labels":[],"label_agreement":null},{"id":"W3121171462","doi":"10.1016/j.neubiorev.2021.01.018","title":"Dysregulation of kynurenine pathway and potential dynamic changes of kynurenine in schizophrenia: A systematic review and meta-analysis","year":2021,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brain and Cognition Discovery Foundation; University Health Network; University of Toronto","funders":"Southwest University","keywords":"Kynurenine; Kynurenic acid; Kynurenine pathway; Quinolinic acid; Schizophrenia (object-oriented programming); Medicine; Antipsychotic; Pharmacology; Internal medicine; Tryptophan; Psychiatry; Chemistry; Biochemistry; Receptor; Amino acid; NMDA receptor","score_opus":0.1288887492321145,"score_gpt":0.37318139877790685,"score_spread":0.24429264954579236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3121171462","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021481812,0.9951242,0.000035501114,0.000028370316,0.000090312475,0.0042180712,0.00026193913,0.000021976924,0.0000047786098],"genre_scores_gemma":[0.0023982308,0.996503,0.00015023543,0.000255629,0.0000066950547,0.00049562554,0.000034674053,0.00004080314,0.0001151184],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9931659,0.0015594153,0.0025571894,0.0015164716,0.0007557676,0.00044523602],"domain_scores_gemma":[0.9959217,0.00003827315,0.0026705407,0.0011033331,0.000091954156,0.00017420063],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013969546,0.00084278313,0.011352282,0.00096946326,0.00009036128,0.00008474159,0.0007386121,0.00024480617,0.000090576475],"category_scores_gemma":[0.0013842458,0.0005643908,0.0018694507,0.0048291325,0.00064315443,0.00024440905,0.00035276476,0.0004214215,0.0000024976896],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000058569617,0.00034096523,0.000002670882,0.7880588,0.00007889294,0.00005591926,0.000049505255,8.982911e-7,0.006272606,0.00019426341,0.000020320254,0.20491925],"study_design_scores_gemma":[0.0007048223,0.00062638475,0.00012248966,0.12505786,0.79581636,0.00043207858,0.000025663607,0.000120504585,0.0002464525,0.000025696945,0.074851446,0.0019702474],"about_ca_topic_score_codex":0.000017250659,"about_ca_topic_score_gemma":0.00007670097,"teacher_disagreement_score":0.79573745,"about_ca_system_score_codex":0.000038815502,"about_ca_system_score_gemma":0.00014207672,"threshold_uncertainty_score":0.99968076},"labels":[],"label_agreement":null},{"id":"W3121395040","doi":"10.20944/preprints201901.0108.v1","title":"In Schizophrenia, Psychomotor Retardation is Associated with Executive and Memory Impairments, Negative and Psychotic Symptoms, Neurotoxic Immune Products and Lower Natural IgM to Malondialdehyde","year":2019,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University; Asahi Glass Foundation","keywords":"Schizophrenia (object-oriented programming); Psychology; Executive functions; Schizoaffective disorder; Neurocognitive; Cognition; Psychosis; Psychiatry","score_opus":0.03529165281980737,"score_gpt":0.29598986486036793,"score_spread":0.26069821204056054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3121395040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919127,0.00024213378,0.0000034360155,0.0020625326,0.00087361183,0.0042927293,0.00007993191,0.00010782755,0.00042508225],"genre_scores_gemma":[0.9962587,0.00027337004,0.00008851312,0.0015180006,0.00005742644,0.00025544636,0.000018134604,0.00007612178,0.0014542853],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99559283,0.0004470962,0.00049423653,0.0024171672,0.00048433908,0.0005643292],"domain_scores_gemma":[0.99801236,0.00024805122,0.00043671543,0.00095331104,0.000110999616,0.00023853978],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045321288,0.0006474051,0.0007024461,0.0004212688,0.00014439254,0.0001194657,0.00043790843,0.0003044778,0.00009172957],"category_scores_gemma":[0.0016079028,0.00060981076,0.000064826505,0.00052126474,0.00036181725,0.0004197514,0.001043223,0.0012091666,0.000072806804],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010448183,0.0017248522,0.2793978,0.001206506,0.00048252835,0.00030001233,0.02419252,0.00017058638,0.67858404,0.00018758084,0.00063821604,0.0026671868],"study_design_scores_gemma":[0.0038160419,0.00028877787,0.89665186,0.0006681722,0.000045794706,0.00004774104,0.00012598097,0.00020008543,0.09633518,0.0009260044,0.00008562922,0.00080870726],"about_ca_topic_score_codex":0.00010304473,"about_ca_topic_score_gemma":0.000046594017,"teacher_disagreement_score":0.6172541,"about_ca_system_score_codex":0.000130507,"about_ca_system_score_gemma":0.00016031585,"threshold_uncertainty_score":0.99963534},"labels":[],"label_agreement":null},{"id":"W3122254970","doi":"10.26685/urncst.215","title":"What are the Recurring Theories Regarding the Pathogenesis of Major Depressive Disorder?","year":2021,"lang":"en","type":"article","venue":"Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University; University of Waterloo","funders":"","keywords":"Major depressive disorder; Monoamine neurotransmitter; Psychology; Pathological; Disease; Clinical psychology; Etiology; Psychiatry; Medicine; Neuroscience; Mood; Serotonin; Pathology; Internal medicine","score_opus":0.05265487295091014,"score_gpt":0.3803749111283106,"score_spread":0.3277200381774005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122254970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85168874,0.010630713,0.000013920437,0.13690723,0.00039219775,0.00016655115,0.0000015909807,0.000017000893,0.00018202985],"genre_scores_gemma":[0.9609155,0.038517907,0.0000430589,0.00033787452,0.000057439695,0.000008169561,1.10213094e-7,0.0000066369325,0.00011331299],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9964625,0.00081601425,0.00049372675,0.0005736559,0.000957769,0.00069628574],"domain_scores_gemma":[0.99568033,0.0031127606,0.0002238706,0.00035250728,0.0004970397,0.00013350073],"candidate_categories":["metaresearch","sts"],"consensus_categories":["sts"],"category_scores_codex":[0.0052976245,0.00014296226,0.00027338398,0.0003521016,0.0020818715,0.0005933434,0.0010475061,0.00015142799,0.0000059641097],"category_scores_gemma":[0.013016934,0.00006972923,0.00007937199,0.0034878054,0.008587173,0.00068114867,0.0009651417,0.0021512513,0.0000025656725],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019440387,0.00034443062,0.10743197,0.0000563246,0.00004489737,0.0005751435,0.00035289643,0.0000075478183,0.0916315,0.20086856,0.00026862518,0.5982237],"study_design_scores_gemma":[0.001656,0.00026442515,0.031121738,0.0005344443,0.00001627063,0.0012087834,0.024493504,0.0007628822,0.03554864,0.9025407,0.0015923269,0.00026030466],"about_ca_topic_score_codex":0.000010640374,"about_ca_topic_score_gemma":0.00015192242,"teacher_disagreement_score":0.70167214,"about_ca_system_score_codex":0.00004198318,"about_ca_system_score_gemma":0.00032350695,"threshold_uncertainty_score":0.9992173},"labels":[],"label_agreement":null},{"id":"W3122692101","doi":"10.20944/preprints201810.0414.v1","title":"In Schizophrenia, Increased Plasma Igm/Iga Responses to Gut Commensal Bacteria are Associated with Negative Symptoms, Neurocognitive Impairments and the Deficit Phenotype","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University; Asahi Glass Foundation","keywords":"Immunology; Morganella morganii; Immune system; Schizophrenia (object-oriented programming); Antibody; Biology; Klebsiella pneumoniae; Medicine; Psychiatry","score_opus":0.05760734319063483,"score_gpt":0.3047963921849923,"score_spread":0.2471890489943575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122692101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937947,0.0000113545975,0.000006348171,0.0012700995,0.000336339,0.002709332,0.0003866849,0.00019074204,0.001294416],"genre_scores_gemma":[0.99562573,0.000024835308,0.000056211586,0.003323393,0.000082636245,0.00050896936,0.000024478159,0.0000944192,0.00025931527],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9938952,0.0023813015,0.0006187007,0.0017851207,0.0005986312,0.00072106154],"domain_scores_gemma":[0.99517596,0.0026663528,0.0006709209,0.001002713,0.00021547219,0.00026857154],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009441601,0.0007253682,0.00084026234,0.0003551684,0.00030246255,0.00015465962,0.0010251694,0.0003436466,0.00028841267],"category_scores_gemma":[0.009348679,0.0005621343,0.00013052256,0.00058689417,0.0009976273,0.00020893822,0.0026297434,0.0012447076,0.0003935134],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.07406927,0.001742281,0.8348137,0.00021891293,0.0005049901,0.00040279207,0.014689934,0.00010411704,0.07206929,0.00042426135,0.0003302413,0.0006302121],"study_design_scores_gemma":[0.00910354,0.00020720306,0.9444624,0.00068594475,0.000068865156,0.00001677938,0.00040141933,0.00019850009,0.042154714,0.0018966474,0.00007824556,0.00072569354],"about_ca_topic_score_codex":0.0005235864,"about_ca_topic_score_gemma":0.0004131402,"teacher_disagreement_score":0.10964874,"about_ca_system_score_codex":0.00020000634,"about_ca_system_score_gemma":0.000300495,"threshold_uncertainty_score":0.999683},"labels":[],"label_agreement":null},{"id":"W3123387007","doi":"10.1503/jpn.190139","title":"The role of anthranilic acid in the increase of depressive symptoms and major depressive disorder during treatment for hepatitis C with pegylated interferon-α2a and oral ribavirin","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Ribavirin; Pegylated interferon; Medicine; Hepatitis C; Major depressive disorder; Pharmacology; Psychiatry; Chronic hepatitis; Gastroenterology; Virology; Internal medicine; Virus; Mood","score_opus":0.00862646928676777,"score_gpt":0.24936504711115504,"score_spread":0.24073857782438726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123387007","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99529696,0.0036382303,0.000047254052,0.00066830683,0.000103654456,0.00020341465,0.000016683754,0.0000025131667,0.00002300216],"genre_scores_gemma":[0.99767923,0.0020846776,0.00007680754,0.00011722346,0.000015473739,0.000008320273,1.5079698e-7,0.0000072298944,0.000010857441],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988634,0.00018124534,0.00031619237,0.00025082976,0.0002044766,0.00018385812],"domain_scores_gemma":[0.99911016,0.00028520572,0.0003370534,0.00014936767,0.000050796065,0.00006743117],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014214724,0.00013312478,0.00021606316,0.00006893048,0.0002672476,0.00006854909,0.00021166982,0.0000305238,0.0000012622737],"category_scores_gemma":[0.00023594346,0.00007074139,0.0000484462,0.00026748437,0.0005541446,0.00023563056,0.00005914948,0.00012634462,2.2641608e-8],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010084669,0.00037975624,0.43765986,0.0000633714,0.000012276098,0.000039088092,0.0010087456,0.000041699743,0.55436236,0.0007446106,0.0000047821536,0.0046750056],"study_design_scores_gemma":[0.004728939,0.0024379808,0.6228446,0.00019439937,0.000057340832,0.0010604957,0.0012042697,0.0006028611,0.36490893,0.0016914177,0.00010949167,0.00015926917],"about_ca_topic_score_codex":0.000037923182,"about_ca_topic_score_gemma":0.00034164963,"teacher_disagreement_score":0.18945341,"about_ca_system_score_codex":0.0000063149932,"about_ca_system_score_gemma":0.00009039991,"threshold_uncertainty_score":0.288475},"labels":[],"label_agreement":null},{"id":"W3123685477","doi":"10.20944/preprints201809.0289.v1","title":"The Role of Aberrations in the Immune-inflammatory Reflex System (IRS) and the Compensatory Immune-regulatory Reflex System (CIRS) in Different Phenotypes of Schizophrenia: The IRS-CIRS Theory of Schizophrenia","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University; Asahi Glass Foundation","keywords":"Immunology; Immune system; Tumor necrosis factor alpha; Internal medicine; Medicine; Endocrinology","score_opus":0.03906542553786534,"score_gpt":0.2847223014645693,"score_spread":0.24565687592670393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123685477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.983915,0.004860649,0.000011098997,0.00032235836,0.00072402746,0.0030294706,0.000062535764,0.00010326908,0.00697159],"genre_scores_gemma":[0.9987934,0.00031658722,0.000014049474,0.00003928364,0.00013853345,0.0005384233,0.0000058836467,0.0000793703,0.000074422846],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.98911613,0.0053164326,0.0025817298,0.0011782736,0.0011704048,0.0006370555],"domain_scores_gemma":[0.9894138,0.003701085,0.0022468213,0.004340006,0.0002208392,0.000077451245],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0066283136,0.00076888775,0.0014109237,0.00033612153,0.0006298187,0.00008236771,0.0040355446,0.00046119405,0.000030312773],"category_scores_gemma":[0.0011088573,0.0003935221,0.00057748554,0.00051560707,0.0042296387,0.00015097692,0.0026457976,0.0017111859,0.000037867972],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0065671187,0.0005401652,0.016767861,0.0026879592,0.0004167341,0.000010719549,0.02250787,0.0006508852,0.26589182,0.6818388,0.000017172028,0.002102871],"study_design_scores_gemma":[0.004486129,0.00006962998,0.7001524,0.0026610855,0.00019792694,0.000033130305,0.026671968,0.0012359066,0.24621661,0.017404731,0.00018127354,0.0006891972],"about_ca_topic_score_codex":0.00031179696,"about_ca_topic_score_gemma":0.00028109967,"teacher_disagreement_score":0.68338454,"about_ca_system_score_codex":0.00025694,"about_ca_system_score_gemma":0.000439378,"threshold_uncertainty_score":0.99985164},"labels":[],"label_agreement":null},{"id":"W3123766236","doi":"10.20944/preprints201907.0262.v1","title":"Chronic Fatigue and Fibromyalgia Symptoms are Key Components of Deficit Schizophrenia and are Strongly Associated with Activated Immune-Inflammatory Pathways","year":2019,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Fibromyalgia; Psychology; Schizophrenia (object-oriented programming); Cognition; Internal medicine; Clinical psychology; Medicine; Psychiatry","score_opus":0.06883185168988257,"score_gpt":0.2733347664086504,"score_spread":0.20450291471876783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123766236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99678004,0.0003859826,0.000019801999,0.000050304665,0.00016508707,0.001209267,0.00017346958,0.00028201434,0.0009340128],"genre_scores_gemma":[0.99922425,0.00013080833,0.000023054457,0.000010052739,0.000022621793,0.00006359845,0.000048468093,0.0001333754,0.00034376155],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9964819,0.00034191427,0.0006073346,0.0014806802,0.00054209586,0.0005461065],"domain_scores_gemma":[0.9968969,0.00025963064,0.0014059768,0.0011498127,0.0001037775,0.00018388545],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024525382,0.0006538135,0.0009133765,0.0002553829,0.00015117269,0.000059613325,0.00066984165,0.0004908483,0.00018430334],"category_scores_gemma":[0.0004979025,0.0006215956,0.00013243823,0.00021524572,0.00047493575,0.00017116444,0.001732074,0.000978557,0.00008288666],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002512574,0.00014327702,0.46973035,0.0009445007,0.0001579446,0.000022138998,0.00035985268,0.00074597565,0.52733856,0.0001819487,0.0000040116074,0.00012014319],"study_design_scores_gemma":[0.0021354582,0.0000668146,0.7984684,0.0023503306,0.000041685445,0.000007272728,0.0001291821,0.00038538993,0.1957537,0.00010914962,0.000018596256,0.0005340387],"about_ca_topic_score_codex":0.00007143022,"about_ca_topic_score_gemma":0.000027100166,"teacher_disagreement_score":0.3315849,"about_ca_system_score_codex":0.00017678914,"about_ca_system_score_gemma":0.00020076738,"threshold_uncertainty_score":0.99962354},"labels":[],"label_agreement":null},{"id":"W3125983212","doi":"","title":"Development of a Novel Neuro-Immune and Opioid-Associated Fingerprint with a Cross-Validated Ability to Identify and Authenticate Unknown Patients with Major Depression: Far Beyond Differentiation, Discrimination and Classification","year":2019,"lang":"en","type":"article","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Major depressive disorder; Artificial intelligence; Fingerprint (computing); Support vector machine; Linear discriminant analysis; Psychology; Depression (economics); Pattern recognition (psychology); Medicine; Computer science; Psychiatry; Mood","score_opus":0.021159613339211483,"score_gpt":0.27304919513940995,"score_spread":0.2518895818001985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3125983212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99611306,0.000008352599,0.0027601232,0.0001223545,0.000039501745,0.0008260761,0.000017433282,0.000043495013,0.00006957549],"genre_scores_gemma":[0.99868196,0.0000032118862,0.0009869249,0.000088549146,0.0000015161047,0.000033455923,0.000031912736,0.000016783999,0.00015566863],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985247,0.00004103679,0.00033832336,0.00057961204,0.0003276243,0.00018867063],"domain_scores_gemma":[0.99920386,0.00011656738,0.00021871799,0.00022181986,0.00014533906,0.000093676346],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014707433,0.0001821465,0.00020025423,0.000106077554,0.00017156237,0.00015217572,0.000108597684,0.000058635345,0.000019851725],"category_scores_gemma":[0.00021316967,0.00012852196,0.000012583345,0.00025225178,0.00014821577,0.00028025385,0.00014808158,0.00007877242,0.0000022368592],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022012909,0.00047110463,0.4279294,0.000108078246,0.000012574133,1.6038014e-7,0.0022754676,0.0000029645637,0.5655847,0.00064345176,0.0000020348016,0.00274991],"study_design_scores_gemma":[0.0023954439,0.00010096655,0.91863644,0.00005839476,0.000016263251,8.0727335e-7,0.00009964109,0.00061874115,0.0778215,0.00005785231,0.000022576682,0.00017138344],"about_ca_topic_score_codex":0.00001578397,"about_ca_topic_score_gemma":0.000067111556,"teacher_disagreement_score":0.49070704,"about_ca_system_score_codex":0.000029778357,"about_ca_system_score_gemma":0.000035768353,"threshold_uncertainty_score":0.5240974},"labels":[],"label_agreement":null},{"id":"W3126297700","doi":"10.1016/j.sleep.2021.02.005","title":"Changed signals of blood adenosine and cytokines are associated with parameters of sleep and/or cognition in the patients with chronic insomnia disorder","year":2021,"lang":"en","type":"article","venue":"Sleep Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Adenosine deaminase; Confounding; Adenosine; Polysomnography; Pittsburgh Sleep Quality Index; Internal medicine; Cytokine; Medicine; Insomnia; Endocrinology; Psychology; Psychiatry; Sleep quality","score_opus":0.019164236286054865,"score_gpt":0.23324115837062365,"score_spread":0.21407692208456877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126297700","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975892,0.000752107,0.000018463832,0.0011288896,0.000025056788,0.0003870644,0.00003956185,0.00001096886,0.00004873876],"genre_scores_gemma":[0.9991631,0.00016588403,0.000018130695,0.0005583471,0.000013910001,0.00002249214,0.000035007783,0.000013001488,0.000010122227],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987962,0.00016841374,0.00022508448,0.0002596062,0.0003751002,0.00017554859],"domain_scores_gemma":[0.9990421,0.0004541091,0.00023211866,0.00014048239,0.00009186382,0.00003931425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013210106,0.00014208454,0.00030806768,0.000102101236,0.000045553115,0.000006978989,0.00009021489,0.000045612036,0.000038815684],"category_scores_gemma":[0.0007895687,0.000074605414,0.000013004646,0.00062565564,0.0004467971,0.00007805068,0.00002827158,0.00011423862,1.761176e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030052501,0.0058007245,0.77851236,0.0012037797,0.00045938735,0.00030764507,0.013447198,0.00010456886,0.16955285,0.00014966528,0.0001988004,0.027257806],"study_design_scores_gemma":[0.018321903,0.0037720175,0.9274304,0.0013748816,0.00027283592,0.000016027898,0.002045017,0.00019419272,0.04622159,0.000105384184,0.00002675567,0.00021902278],"about_ca_topic_score_codex":0.00002848277,"about_ca_topic_score_gemma":0.0007473223,"teacher_disagreement_score":0.14891803,"about_ca_system_score_codex":0.0000077315135,"about_ca_system_score_gemma":0.000021843134,"threshold_uncertainty_score":0.30423203},"labels":[],"label_agreement":null},{"id":"W3126489438","doi":"10.1186/s12974-021-02091-5","title":"Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression","year":2021,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":139,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Sanming Project of Medicine in Shenzhen; Shenzhen-Hong Kong Institute of Brain Science; Collaborative Innovation Center for Water Treatment Technology and Materials","keywords":"Fluoxetine; Inhibitory postsynaptic potential; Mechanism (biology); Depression (economics); Phosphorylation; Neurology; Pharmacology; Neuroscience; Chemistry; Psychology; Biology; Medicine; Cell biology; Internal medicine; Serotonin; Receptor; Philosophy","score_opus":0.031703661239243126,"score_gpt":0.2602108596599728,"score_spread":0.2285071984207297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126489438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997533,0.0000135971795,0.0017373537,0.00028898942,0.00018886145,0.00012682012,0.0000023211442,0.00002066449,0.00008836264],"genre_scores_gemma":[0.99921817,0.000035339504,0.0005515647,0.00004184681,0.00006660406,0.0000017322169,0.0000015335106,0.000022151107,0.000061034032],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981886,0.00029867873,0.0006016386,0.00024542483,0.0004971493,0.00016846739],"domain_scores_gemma":[0.9986182,0.00013639603,0.0007139564,0.0002474753,0.00019124588,0.00009275743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029896369,0.00014525458,0.00025406422,0.00024810998,0.00007018805,0.000041331845,0.00017805133,0.000100830825,0.000024586143],"category_scores_gemma":[0.0005970585,0.00013917693,0.0001026868,0.00030609497,0.000029777415,0.0011276576,0.000055483895,0.00029838545,0.0000030017914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001867764,0.00020195842,0.00013986722,0.000028518272,0.0000019274205,0.000031813343,0.0002668458,0.01205536,0.98139554,0.0002192059,0.000008932145,0.005463275],"study_design_scores_gemma":[0.0008708275,0.00011984543,0.005898788,0.00005048504,0.0000061474007,0.00004000212,0.000027808075,0.10366524,0.8860704,0.0031436444,0.0000018988154,0.000104952946],"about_ca_topic_score_codex":0.0000032054334,"about_ca_topic_score_gemma":0.000020648473,"teacher_disagreement_score":0.095325164,"about_ca_system_score_codex":0.00005079128,"about_ca_system_score_gemma":0.00013883653,"threshold_uncertainty_score":0.567547},"labels":[],"label_agreement":null},{"id":"W3127649448","doi":"10.12740/pp/120084","title":"A hormetic approach to understanding antidepressant effectiveness and the development of antidepressant tolerance – A conceptual view","year":2020,"lang":"en","type":"review","venue":"Psychiatria Polska","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Antidepressant; Serotonergic; Serotonin; Hormesis; Neuroscience; Neurotransmitter; Pharmacology; Medicine; Psychology; Central nervous system; Internal medicine; Hippocampus; Receptor","score_opus":0.09561857374467982,"score_gpt":0.32568381519512357,"score_spread":0.23006524145044377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127649448","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022195694,0.9834732,0.008576,0.00013140112,0.0005582028,0.0042596622,0.000066616136,0.000083512154,0.0026294552],"genre_scores_gemma":[0.035377827,0.9618574,0.0018603227,0.00023784966,0.00014013764,0.00040887843,0.000006545776,0.00009830189,0.000012740222],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9952434,0.0013650093,0.0011037386,0.0012007145,0.0005504917,0.00053669023],"domain_scores_gemma":[0.9970431,0.0015485719,0.0005960763,0.00057225866,0.000019093635,0.0002209249],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008150566,0.0006908199,0.002550263,0.00021841053,0.0003310224,0.00011929795,0.0009386081,0.00019295845,0.0000096926615],"category_scores_gemma":[0.0004452598,0.00043954785,0.00048272646,0.0011741478,0.00070547557,0.00009302114,0.0003725479,0.00049233437,0.000025607447],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010418982,0.0006035975,0.00004527811,0.058327053,0.0005537036,0.000016267284,0.009171974,0.00002211524,0.00013196058,0.19237295,0.00065136526,0.73706186],"study_design_scores_gemma":[0.007928801,0.00022046863,0.00021928338,0.01789968,0.00093653426,0.00015321514,0.0012323696,0.00010354484,0.0002936177,0.0022806425,0.9666813,0.0020505644],"about_ca_topic_score_codex":0.000008806696,"about_ca_topic_score_gemma":0.0000035454311,"teacher_disagreement_score":0.96602994,"about_ca_system_score_codex":0.00009045279,"about_ca_system_score_gemma":0.00044207787,"threshold_uncertainty_score":0.9998056},"labels":[],"label_agreement":null},{"id":"W3127840691","doi":"10.1002/dev.22103","title":"Prenatal maternal distress and immune cell epigenetic profiles at 3‐months of age","year":2021,"lang":"en","type":"article","venue":"Developmental Psychobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Athabasca University; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Children's Hospital Foundation; AllerGen","keywords":"Epigenetics; Immune system; Distress; Psychology; Medicine; Developmental psychology; Biology; Genetics; Clinical psychology; Gene","score_opus":0.014733352862627672,"score_gpt":0.2439701418963265,"score_spread":0.22923678903369882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127840691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909638,0.00050673063,0.000011545307,0.000067903755,0.00031635028,0.00013956007,0.00010028003,0.000022492344,0.00787134],"genre_scores_gemma":[0.99696475,0.00015551022,0.00071812846,0.00019180607,0.000012291983,0.000016112108,0.00005239074,0.000012314754,0.0018766774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893856,0.0000803311,0.00025135285,0.0003984736,0.00007941788,0.00025185058],"domain_scores_gemma":[0.99965495,0.00007011424,0.000081643266,0.00012545835,0.000011650574,0.00005618468],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000036565867,0.0001386322,0.00018416658,0.00003983199,0.00007912034,0.000013512004,0.00016766373,0.0000749686,0.00057091063],"category_scores_gemma":[0.000034146644,0.00012531054,0.000037629292,0.00010464194,0.00028161763,0.000036643116,0.00021499094,0.00007056636,0.00005060292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006653405,0.00009488863,0.015212368,0.00007320754,0.0000065318313,0.00008291094,0.00028435964,3.7162653e-7,0.9813231,0.00015750692,0.00017335822,0.0025248437],"study_design_scores_gemma":[0.00056162575,0.000032015192,0.1977838,0.000022036398,0.0000016865714,0.0001135884,0.000108031876,0.0000016398441,0.8002282,0.00022665062,0.00080070033,0.000120050405],"about_ca_topic_score_codex":0.0000137932775,"about_ca_topic_score_gemma":0.000029590852,"teacher_disagreement_score":0.18257144,"about_ca_system_score_codex":0.000023245138,"about_ca_system_score_gemma":0.00003053176,"threshold_uncertainty_score":0.6251071},"labels":[],"label_agreement":null},{"id":"W3130178666","doi":"10.1016/j.cytogfr.2021.02.003","title":"Latest developments in tryptophan metabolism: Understanding its role in B cell immunity","year":2021,"lang":"en","type":"review","venue":"Cytokine & Growth Factor Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Institut National de la Recherche Scientifique","funders":"","keywords":"Kynurenine; Tryptophan; Kynurenine pathway; Biology; Immunity; Tryptophan Metabolism; Inflammation; Immune system; Homeostasis; Metabolic pathway; Cell biology; Immunology; Metabolism; Biochemistry; Amino acid","score_opus":0.1461052427460758,"score_gpt":0.3339122873831919,"score_spread":0.1878070446371161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130178666","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00038457918,0.9923281,0.000011495691,0.000021933907,0.00048493344,0.0024680416,0.00013169415,0.00007354781,0.004095671],"genre_scores_gemma":[0.0028344311,0.9958478,0.00008976226,0.00024487794,0.00007913524,0.0003255975,0.00012426105,0.00014690212,0.00030721255],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9925788,0.002152482,0.0022707954,0.0014210872,0.0005036552,0.0010731788],"domain_scores_gemma":[0.9973931,0.0005899488,0.0009184881,0.0008098452,0.00003768803,0.0002509652],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007030249,0.0012120847,0.0047109853,0.00092502905,0.00016024255,0.00019172742,0.0013962963,0.00050634396,0.0003836295],"category_scores_gemma":[0.0017165635,0.0010175656,0.0008378072,0.0034910892,0.00009486611,0.0004333982,0.00050930906,0.0016082181,0.00051035645],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003156192,0.0019901379,0.0003320523,0.07264519,0.00007777097,0.0007793948,0.0021063932,0.0000010485747,0.0039606956,0.006639472,0.0011367815,0.9102995],"study_design_scores_gemma":[0.000816334,0.000019110797,0.00013582544,0.0131151145,0.000064261454,0.000023237171,0.000064228545,0.000001175655,0.001621297,0.00009370891,0.9830385,0.0010072371],"about_ca_topic_score_codex":0.00003924943,"about_ca_topic_score_gemma":0.0000967338,"teacher_disagreement_score":0.9819017,"about_ca_system_score_codex":0.0008334376,"about_ca_system_score_gemma":0.0005641783,"threshold_uncertainty_score":0.99922746},"labels":[],"label_agreement":null},{"id":"W3131240808","doi":"10.1016/j.neubiorev.2021.02.031","title":"Association between chronic psychoactive substances use and systemic inflammation: A systematic review and meta-analysis","year":2021,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Meta-analysis; Medicine; Cannabis; Amphetamine; Publication bias; Psychiatry; Nicotine; Internal medicine","score_opus":0.259743110843634,"score_gpt":0.4070472484103664,"score_spread":0.14730413756673238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3131240808","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000035510046,0.99255383,0.000035649886,0.00005689492,0.00013353527,0.006848916,0.00025217907,0.00007036058,0.000013116058],"genre_scores_gemma":[0.00008896868,0.9966413,0.00003086374,0.00093665987,0.000044334454,0.0015814693,0.00003105086,0.000047386857,0.00059797487],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99080354,0.0030089861,0.002566186,0.001998344,0.0009886338,0.0006343039],"domain_scores_gemma":[0.99459076,0.00018097892,0.0036135975,0.0011825707,0.00013849563,0.00029362447],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020715478,0.0010166552,0.011184944,0.00046858308,0.00036338027,0.0009023788,0.00079106283,0.0003301376,0.00008938125],"category_scores_gemma":[0.003873095,0.0006806261,0.00250714,0.0041664625,0.0002787384,0.0011017865,0.000226929,0.00064473937,0.00004309347],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[5.8714477e-7,0.000058036792,0.000044255026,0.9252482,0.00040622937,0.000032681244,0.00007595563,1.701087e-7,0.00010851386,0.000068098765,0.0005354458,0.07342183],"study_design_scores_gemma":[0.000055952096,0.000049795006,0.000010797614,0.035235967,0.49118093,0.000065380824,0.000007891982,0.0000012224797,0.000004313316,0.0000019326185,0.47283295,0.0005528573],"about_ca_topic_score_codex":0.000011449098,"about_ca_topic_score_gemma":0.00003403269,"teacher_disagreement_score":0.89001226,"about_ca_system_score_codex":0.0003547826,"about_ca_system_score_gemma":0.00022293077,"threshold_uncertainty_score":0.99956447},"labels":[],"label_agreement":null},{"id":"W3131361978","doi":"10.1016/j.neuropharm.2021.108503","title":"Clozapine attenuates mitochondrial dysfunction, inflammatory gene expression, and behavioral abnormalities in an animal model of schizophrenia","year":2021,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Institute for Medical Research Development","keywords":"Clozapine; Schizophrenia (object-oriented programming); Pathophysiology; Psychosis; Immune system; Prefrontal cortex; Downregulation and upregulation; Inflammation; Medicine; Innate immune system; Immunology; Psychology; Neuroscience; Internal medicine; Gene; Biology; Psychiatry; Cognition","score_opus":0.03710510585229051,"score_gpt":0.29596414623458206,"score_spread":0.25885904038229157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3131361978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988022,0.0001548856,0.000025130566,0.0001614093,0.00055655575,0.00016819854,0.000036723566,0.0000593955,0.000035519173],"genre_scores_gemma":[0.998255,0.00021485685,0.0004816383,0.0007321314,0.00014443799,0.000031401032,0.000005875045,0.000027808825,0.000106863685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822444,0.00038119566,0.0003756749,0.0005359357,0.00017767219,0.00030509604],"domain_scores_gemma":[0.99937785,0.00011930252,0.00011131155,0.00019855532,0.00007582537,0.00011713266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054726806,0.000185,0.00025473596,0.00015746706,0.000093252806,0.00002504192,0.00018587,0.00010415608,0.00016240084],"category_scores_gemma":[0.00012384896,0.00019208975,0.000044995304,0.00021300247,0.00029349353,0.00031464678,0.0001701614,0.00023142435,0.00000513482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009281393,0.00022667038,0.0024779674,0.00002495382,0.0000017047025,0.00017042326,0.00033528171,0.0006796334,0.9943546,0.00018595274,0.00024691975,0.00036777023],"study_design_scores_gemma":[0.0034545565,0.00025926458,0.0069753807,0.000007077961,0.000012264787,0.00005154469,0.00007581133,0.0032903284,0.9853942,0.00012888675,0.00017875487,0.00017193353],"about_ca_topic_score_codex":0.0000057958578,"about_ca_topic_score_gemma":0.00002107932,"teacher_disagreement_score":0.008960387,"about_ca_system_score_codex":0.000014052826,"about_ca_system_score_gemma":0.0001311992,"threshold_uncertainty_score":0.78331923},"labels":[],"label_agreement":null},{"id":"W3131540936","doi":"10.3389/fimmu.2021.590532","title":"Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production","year":2021,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Horizon 2020; Deutsches Krebsforschungszentrum; Deutsche Forschungsgemeinschaft; Bundesministerium für Bildung und Forschung; Ministère de l'Économie, de la Science et de l'Innovation - Québec; European Commission","keywords":"Tryptamine; Kynurenine; Tryptophan; Biochemistry; Metabolism; Homeostasis; Chemistry; Biology; Cell biology; Amino acid","score_opus":0.015928609084008942,"score_gpt":0.23589139957164723,"score_spread":0.21996279048763828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3131540936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98376316,0.0059427377,0.0009002332,0.0022781491,0.0045534107,0.00026029837,0.000019747265,0.00017349124,0.0021087565],"genre_scores_gemma":[0.9911629,0.0018820686,0.0045037395,0.0007765919,0.0001201742,0.00006055848,0.000029335803,0.00003849467,0.0014261628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977023,0.00041729774,0.00035902153,0.0007697975,0.00020121325,0.00055038923],"domain_scores_gemma":[0.9991641,0.00006976403,0.00010567499,0.00054772414,0.00005301093,0.000059701837],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013933508,0.0002412245,0.00040210868,0.00034817486,0.0001332805,0.00004499,0.00036673705,0.00020811152,0.00017942037],"category_scores_gemma":[0.0021131309,0.00025329986,0.00010737349,0.0010913687,0.00035717667,0.00024307265,0.0001399509,0.00035285717,0.000050869567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029040783,0.00051744154,0.0024621056,0.000031732714,0.0000467575,0.00021231506,0.00071489724,0.000017147813,0.7815514,0.0011051215,0.011595488,0.20145519],"study_design_scores_gemma":[0.0018464801,0.00011542818,0.0629885,0.00002817786,0.000011148483,0.00012559589,0.0011867003,0.000086649954,0.89987886,0.005303447,0.028049825,0.00037921782],"about_ca_topic_score_codex":0.00007293566,"about_ca_topic_score_gemma":0.00003554547,"teacher_disagreement_score":0.20107597,"about_ca_system_score_codex":0.00013929853,"about_ca_system_score_gemma":0.00019402677,"threshold_uncertainty_score":0.9999919},"labels":[],"label_agreement":null},{"id":"W3131673246","doi":"10.1038/s41398-021-01248-3","title":"Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response","year":2021,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; McMaster University; Queen's University; St. Joseph’s Healthcare Hamilton; University of British Columbia; McGill University; Douglas Mental Health University Institute; University Health Network; University of Toronto; Vancouver Coastal Health; Centre for Addiction and Mental Health","funders":"","keywords":"Neuroinflammation; Antidepressant; Schizophrenia (object-oriented programming); Psychology; Neuroscience; Psychiatry; Medicine; Internal medicine; Hippocampus; Inflammation","score_opus":0.016247427842266828,"score_gpt":0.25611475922989246,"score_spread":0.23986733138762564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3131673246","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99060655,0.0017583246,0.0004740242,0.00668038,0.000051889052,0.00015076161,0.000023541726,0.00001897988,0.00023554133],"genre_scores_gemma":[0.9988819,0.00019667752,0.00025490558,0.0005933697,0.000017727814,0.000007333631,0.000013684293,0.000009713954,0.000024686988],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99864656,0.00023866646,0.00034329738,0.00032866411,0.0003043634,0.00013843551],"domain_scores_gemma":[0.999011,0.0005649462,0.00010688978,0.00022387462,0.000051252948,0.00004208427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027785727,0.00010686451,0.00017014857,0.00014912298,0.00008070216,0.000028681803,0.00013322807,0.000042909247,0.00007257588],"category_scores_gemma":[0.0005091085,0.00008819976,0.00009044623,0.0014367164,0.00010472563,0.00015721752,0.000013030805,0.00010915905,0.00000218661],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030839324,0.0001248548,0.9536055,0.00012272254,0.00005528018,0.0000082447705,0.0006998781,0.0143959075,0.028868679,0.0017331956,0.000014091688,0.000063266474],"study_design_scores_gemma":[0.00052976405,0.000011712295,0.99107766,0.000012634265,0.000044670272,0.0000019833537,0.000060720962,0.0009951058,0.0022093891,0.004855453,0.00010315898,0.00009773504],"about_ca_topic_score_codex":0.0000043221116,"about_ca_topic_score_gemma":0.00046829827,"teacher_disagreement_score":0.037472185,"about_ca_system_score_codex":0.000003444572,"about_ca_system_score_gemma":0.0002895296,"threshold_uncertainty_score":0.3596682},"labels":[],"label_agreement":null},{"id":"W3132273857","doi":"10.3389/fpsyt.2021.612471","title":"The Role of Peripheral Inflammation in Clinical Outcome and Brain Imaging Abnormalities in Psychosis: A Systematic Review","year":2021,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"King's College London; Medical Research Council; National Institute for Health and Care Research; Department of Health and Social Care; South London and Maudsley NHS Foundation Trust","keywords":"Neuroimaging; Psychosis; Medicine; Schizophrenia (object-oriented programming); Brain Structure and Function; Antipsychotic; Inflammation; Internal medicine; Meta-analysis; Bioinformatics; Psychiatry","score_opus":0.022431204298782887,"score_gpt":0.34289343384886267,"score_spread":0.3204622295500798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3132273857","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014271778,0.99364185,0.000018509549,0.0006870358,0.0032428363,0.0018886268,0.000011433022,0.000016840457,0.00035016227],"genre_scores_gemma":[0.000098916025,0.99831545,0.00039616003,0.00064158347,0.00006624936,0.000364237,0.000006326318,0.000037191647,0.000073874624],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.993249,0.0023695244,0.003114097,0.0005905255,0.00029906209,0.00037778137],"domain_scores_gemma":[0.9978044,0.00059480185,0.00091839547,0.0006103372,0.00001736638,0.00005470466],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0023772833,0.00037724152,0.002652258,0.00034757782,0.000056257042,0.00007785113,0.0005999816,0.0001977238,0.0000059728795],"category_scores_gemma":[0.0018451413,0.0002752843,0.0004387629,0.00093900925,0.00022968641,0.00018425108,0.00010119469,0.00075597124,0.0000021411151],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001165098,0.00011670303,0.03190126,0.7327783,0.000030765827,0.000010841311,0.0002761005,6.3425693e-7,1.6937705e-7,0.0019331647,0.0038626136,0.22907779],"study_design_scores_gemma":[0.00093258,0.000031621865,0.0006607943,0.8701659,0.00019386546,0.000048992842,0.0027900282,0.00015248657,3.392783e-7,0.0022960538,0.12209183,0.00063551526],"about_ca_topic_score_codex":0.000016603415,"about_ca_topic_score_gemma":0.0001742858,"teacher_disagreement_score":0.22844227,"about_ca_system_score_codex":0.00009300308,"about_ca_system_score_gemma":0.00021649076,"threshold_uncertainty_score":0.99996996},"labels":[],"label_agreement":null},{"id":"W3133654402","doi":"10.1002/ajmg.b.32839","title":"Machine learning and bioinformatic analysis of brain and blood <scp>mRNA</scp> profiles in major depressive disorder: A case–control study","year":2021,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canada First Research Excellence Fund; McGill University Health Centre","keywords":"Major depressive disorder; Microarray analysis techniques; Microarray; Gene expression; Area under the curve; Gene expression profiling; Gene; Dorsolateral prefrontal cortex; Receiver operating characteristic; Medicine; Oncology; Prefrontal cortex; Internal medicine; Bioinformatics; Artificial intelligence; Machine learning; Biology; Computer science; Genetics; Psychiatry; Cognition","score_opus":0.007892840631490615,"score_gpt":0.25802645986087486,"score_spread":0.25013361922938426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133654402","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98890275,0.009361798,0.00055953296,0.00066340854,0.00014958881,0.00027846338,0.000037806643,0.0000104350065,0.000036190955],"genre_scores_gemma":[0.9894053,0.008945451,0.00087164016,0.0006581311,0.00006102436,0.0000057981447,0.000001415129,0.00003174595,0.00001952691],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99548364,0.0011899681,0.001295605,0.0004406613,0.0011562417,0.000433891],"domain_scores_gemma":[0.99618995,0.0018699315,0.0010557491,0.00027566857,0.00013123301,0.0004774718],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007076933,0.00030333985,0.00091770256,0.0007775164,0.00013356234,0.0000742147,0.00037886496,0.00008329164,0.000031529817],"category_scores_gemma":[0.0034374685,0.0002633292,0.00017613603,0.0026885774,0.00053491956,0.00005156467,0.0002179044,0.0006989361,7.365654e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051117597,0.0014057882,0.90915495,0.0000910045,0.0006590131,0.0033077693,0.002374011,0.0025440939,0.0030431873,0.000015669086,0.000043272536,0.07731012],"study_design_scores_gemma":[0.025132332,0.013170273,0.7838482,0.00016565302,0.006967452,0.0151565205,0.025706895,0.12305943,0.0038321048,0.00017562087,0.00199493,0.00079058897],"about_ca_topic_score_codex":0.000032531836,"about_ca_topic_score_gemma":0.0001672863,"teacher_disagreement_score":0.12530676,"about_ca_system_score_codex":0.0000073920214,"about_ca_system_score_gemma":0.00023949382,"threshold_uncertainty_score":0.9999819},"labels":[],"label_agreement":null},{"id":"W3134618529","doi":"10.1038/s41380-021-01051-y","title":"Peripheral inflammatory biomarkers define biotypes of bipolar depression","year":2021,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brain and Cognition Discovery Foundation; Foothills Medical Centre; University of Calgary; Centre for Addiction and Mental Health; University Health Network; University of Toronto; Toronto Metropolitan University; Queen's University","funders":"National Institute on Aging; National Institutes of Health; Stanley Medical Research Institute; U.S. Department of Health and Human Services","keywords":"Depression (economics); Peripheral; Bipolar disorder; Psychology; Psychiatry; Neuroscience; Medicine; Internal medicine; Cognition","score_opus":0.007752959265022849,"score_gpt":0.2327763598979625,"score_spread":0.22502340063293966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134618529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848054,0.0092813065,0.00081189367,0.00075405935,0.00076748285,0.00010876859,0.000012232396,0.00007874618,0.0033801273],"genre_scores_gemma":[0.9952182,0.00011461355,0.0030862289,0.0014079926,0.000035265926,0.0000059279137,0.000006213306,0.00003204044,0.00009349289],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868137,0.00015088591,0.0002397704,0.00041880223,0.00026701664,0.00024218309],"domain_scores_gemma":[0.99931926,0.000029322853,0.00009421661,0.00043950143,0.000033221535,0.00008448296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006766511,0.00015620525,0.00015702909,0.000091746355,0.000079969075,0.000025576343,0.00022208708,0.00008543384,0.00020619757],"category_scores_gemma":[0.00017101444,0.0001516502,0.00016451364,0.00042948732,0.00012428054,0.00007286953,0.00009278564,0.00012003449,0.000027855931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037791713,0.00013726582,0.017031264,0.000065036875,0.000018016342,0.00005445297,0.000038879196,0.000024029263,0.9746707,0.003975826,0.0007969463,0.0031497888],"study_design_scores_gemma":[0.0007264697,0.000036311565,0.014580881,0.000055877477,0.000011546254,0.00004364746,0.00008763526,0.00007323989,0.9746819,0.0015907834,0.0078967875,0.00021488717],"about_ca_topic_score_codex":0.000006543335,"about_ca_topic_score_gemma":0.000014437368,"teacher_disagreement_score":0.010412841,"about_ca_system_score_codex":0.000011737772,"about_ca_system_score_gemma":0.0001603356,"threshold_uncertainty_score":0.61841154},"labels":[],"label_agreement":null},{"id":"W3134661149","doi":"10.1503/jpn.200208","title":"COVID-19 infection causes a reduction in neutrophil counts in patients taking clozapine","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"St. George's, University of London; King's College London","keywords":"Neutropenia; Clozapine; Absolute neutrophil count; Medicine; White blood cell; Internal medicine; Lymphocyte; Gastroenterology; Immunology; Chemotherapy; Schizophrenia (object-oriented programming); Psychiatry","score_opus":0.0333041130540806,"score_gpt":0.30274758080233216,"score_spread":0.26944346774825156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134661149","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99578387,0.00013536806,0.000039417446,0.0012998397,0.0024738049,0.00004737303,0.000001478832,0.000006348675,0.0002124954],"genre_scores_gemma":[0.9970673,0.0007030963,0.00004883276,0.0020708276,0.00006963525,6.750103e-7,1.1760529e-7,0.0000042638953,0.00003524963],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991208,0.00010996058,0.00024211683,0.00019421757,0.00020247784,0.00013047096],"domain_scores_gemma":[0.9995766,0.000029209057,0.00020418431,0.00006871419,0.000023639523,0.00009761701],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015440384,0.00006705042,0.00009846234,0.00020257328,0.00007719935,0.00004156678,0.000081505925,0.000031863172,0.000024654466],"category_scores_gemma":[0.0010015027,0.00006180103,0.000029108194,0.00068081054,0.00008618149,0.00030186123,0.00002390618,0.0001999705,0.0000016247078],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031607132,0.0015508927,0.6916825,0.00014823496,0.0000014778844,0.00018373589,0.00050566864,0.0016996821,0.29310733,0.003918764,0.0017725007,0.00511311],"study_design_scores_gemma":[0.0020263765,0.00036192447,0.9800587,0.0000851107,0.000003778749,0.0004652702,0.00006255577,0.00014070907,0.0074847466,0.0024045552,0.0067434306,0.00016280633],"about_ca_topic_score_codex":0.000009595288,"about_ca_topic_score_gemma":0.000034727756,"teacher_disagreement_score":0.2883762,"about_ca_system_score_codex":0.00003763974,"about_ca_system_score_gemma":0.0002660934,"threshold_uncertainty_score":0.2520173},"labels":[],"label_agreement":null},{"id":"W3134667368","doi":"10.1093/jcag/gwab002.007","title":"A8 DIETARY TRYPTOPHAN MODULATES KYNURENINE AND INDOLE PRODUCTION IN HEALTHY INDIVIDUALS","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Tryptophan; Kynurenine; Crossover study; Placebo; Kynurenine pathway; Serotonin; Internal medicine; Medicine; Mood; Endocrinology; Physiology; Biology; Amino acid; Biochemistry; Receptor; Psychiatry","score_opus":0.015624201186935235,"score_gpt":0.23954929728252797,"score_spread":0.22392509609559275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134667368","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9563011,0.000046787452,0.0000013954871,0.042958267,0.0005577009,0.00007183886,0.000015433146,0.0000019317342,0.00004554911],"genre_scores_gemma":[0.99679625,0.00006726194,0.00007705609,0.0028486897,0.00007844432,0.0000010514874,0.0000010778879,0.000006268918,0.00012389175],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99851114,0.00050711405,0.0003827633,0.00013159265,0.00021545467,0.00025191513],"domain_scores_gemma":[0.99900895,0.0000757172,0.0006047696,0.000091345835,0.00010444801,0.00011473831],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050086103,0.000074144365,0.00022871036,0.00022338248,0.0000806215,0.000017717537,0.00015326604,0.00007906286,0.000019198429],"category_scores_gemma":[0.0015050517,0.00006283028,0.0000672554,0.00022170087,0.00005843259,0.0001172269,0.000029462148,0.00027212704,6.8111154e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015847296,0.00008283351,0.9710112,0.000014356911,0.000027293088,0.0000144448695,0.0004701506,0.0002918037,0.025280522,0.00005102399,0.0020647987,0.00053309643],"study_design_scores_gemma":[0.0013979214,0.00035741657,0.98598415,0.0000312717,0.000010417786,0.00012605786,0.00010383204,0.00002530113,0.010637667,0.00084508926,0.00044088156,0.000040000854],"about_ca_topic_score_codex":0.0006799866,"about_ca_topic_score_gemma":0.18271658,"teacher_disagreement_score":0.1820366,"about_ca_system_score_codex":0.00032614288,"about_ca_system_score_gemma":0.00028067856,"threshold_uncertainty_score":0.8321967},"labels":[],"label_agreement":null},{"id":"W3135612113","doi":"10.1002/mnfr.202100078","title":"The Kynurenine Pathway Is Upregulated by Methyl‐deficient Diet and Changes Are Averted by Probiotics","year":2021,"lang":"en","type":"article","venue":"Molecular Nutrition & Food Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"PerkinElmer Biosignal","funders":"Beckett-Fonden; Danmarks Frie Forskningsfond; Aarhus Universitet","keywords":"Kynurenine pathway; Downregulation and upregulation; Kynurenine; Chemistry; Biology; Biochemistry; Tryptophan","score_opus":0.046533567609825646,"score_gpt":0.30287966513188835,"score_spread":0.2563460975220627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135612113","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9174303,0.026732948,0.0003494512,0.052233767,0.00015340607,0.0015028496,0.00071866316,0.00014619355,0.00073246355],"genre_scores_gemma":[0.99564826,0.0020489045,0.000053057902,0.0010180952,0.000019365043,0.00010728583,0.00007447889,0.000036514884,0.0009940248],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968511,0.0007916227,0.00018139763,0.0006457765,0.00091120554,0.00061892613],"domain_scores_gemma":[0.9987929,0.00026994123,0.00005474445,0.00043775755,0.0002853417,0.00015931319],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004103381,0.00017515194,0.00016979652,0.000105082894,0.00065078493,0.0003139449,0.0003083392,0.00014102094,0.000047707126],"category_scores_gemma":[0.0006433074,0.00014160245,0.000065777305,0.0011284671,0.00043103402,0.00005272659,0.00024102352,0.00043870954,0.00001895975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009673868,0.00042540403,0.0000028701104,0.00007190334,0.000015227278,0.00004131393,0.0001294082,6.808045e-7,0.9612641,0.0005618246,0.03593801,0.0014525247],"study_design_scores_gemma":[0.00096506916,0.0006681694,0.000024904517,0.00006383483,0.00000388436,0.000013441816,0.00037188214,0.00022054286,0.91192764,0.0011008716,0.08448456,0.00015518442],"about_ca_topic_score_codex":0.000005529098,"about_ca_topic_score_gemma":0.000021754699,"teacher_disagreement_score":0.07821801,"about_ca_system_score_codex":0.00004212988,"about_ca_system_score_gemma":0.00005232667,"threshold_uncertainty_score":0.577438},"labels":[],"label_agreement":null},{"id":"W3135783891","doi":"10.1097/cxa.0000000000000107","title":"Recent Advances in Biomarkers of Addiction: A Narrative Review","year":2021,"lang":"en","type":"review","venue":"The Canadian Journal of Addiction","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Queen's University; University of Calgary","funders":"","keywords":"Addiction; Narrative review; Psychology; Modalities; Psychiatry; Medicine; Psychotherapist","score_opus":0.045481578016078425,"score_gpt":0.31772098747008226,"score_spread":0.2722394094540038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135783891","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000003329268,0.9957704,0.0000037503892,0.0007752131,0.0010377384,0.0004051963,0.00007290408,0.000004039524,0.0019274313],"genre_scores_gemma":[0.000031413463,0.9993624,0.000013410954,0.0003526141,0.00012367865,0.0000144706955,0.0000115351495,0.000020037187,0.00007044967],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99733573,0.0008987391,0.0009820476,0.00021500095,0.00031972188,0.0002487287],"domain_scores_gemma":[0.99784726,0.00026974487,0.0012442055,0.00024397268,0.00017199031,0.00022283838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006876524,0.00023347177,0.0010322325,0.00047725617,0.00017420022,0.00003364137,0.00042951253,0.00013027759,0.00075697096],"category_scores_gemma":[0.0012547555,0.0001585219,0.00040772132,0.0015781936,0.00023510716,0.0002485849,0.000013831493,0.00060825574,0.00000802978],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005373154,0.000012459502,4.65935e-7,0.0011507581,0.00004725242,0.000060399816,0.00018740761,0.0000039130596,0.0000014877733,0.0000752129,0.01342226,0.98503304],"study_design_scores_gemma":[0.00014032736,0.00007778518,0.000004688693,0.051682238,0.00017892761,0.00043661465,0.00013431018,9.2799485e-7,0.000014116973,0.000033225344,0.9471746,0.00012222704],"about_ca_topic_score_codex":0.00018987397,"about_ca_topic_score_gemma":0.01752309,"teacher_disagreement_score":0.9849108,"about_ca_system_score_codex":0.00046199447,"about_ca_system_score_gemma":0.003265901,"threshold_uncertainty_score":0.9778296},"labels":[],"label_agreement":null},{"id":"W3135891413","doi":"10.1101/2021.02.28.21251786","title":"Novel polygenic risk score links depression-related cortical transcriptomic changes to brain morphology and symptom severity","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Gyrification; Depression (economics); Major depressive disorder; Neurogenetics; Neuroimaging; Internal medicine; Bipolar disorder; Cohort; Transcriptome; Medicine; Brain morphometry; Prefrontal cortex; Amygdala; Psychology; Oncology; Psychiatry; Biology; Magnetic resonance imaging; Gene; Gene expression; Genetics; Cognition; Cerebral cortex","score_opus":0.030791809062303006,"score_gpt":0.26952530348606474,"score_spread":0.23873349442376174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135891413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895539,0.00083042885,0.001523014,0.0052392166,0.0014380785,0.00072696875,0.00018653997,0.0003803519,0.000121491146],"genre_scores_gemma":[0.9931061,0.00052853575,0.00042040812,0.0054156417,0.00009552181,0.00009646814,0.000025315481,0.0001043405,0.00020761456],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9961154,0.00054990815,0.00047569434,0.0017744162,0.00039964903,0.00068495143],"domain_scores_gemma":[0.997842,0.00061424775,0.00019382525,0.00086326315,0.000049011844,0.00043765263],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00038302466,0.00053200213,0.0006846046,0.00025441777,0.00021028478,0.00014893449,0.0007041467,0.0011301519,0.00026178363],"category_scores_gemma":[0.0019585844,0.0005088891,0.0002016176,0.00039924448,0.0003792853,0.000068406625,0.0009267589,0.0026300875,0.000033680113],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000099496574,0.00023193391,0.027331468,0.000115903895,0.0000465283,0.00013880891,0.0016621586,0.00007294763,0.9660953,0.00007288641,0.0003214062,0.0038111543],"study_design_scores_gemma":[0.0018817536,0.00014083394,0.81692165,0.00036122196,0.00011102931,0.00031106616,0.00019532301,0.001926445,0.17570204,0.0004819177,0.0008523464,0.0011143527],"about_ca_topic_score_codex":0.00022019695,"about_ca_topic_score_gemma":0.00044122912,"teacher_disagreement_score":0.7903933,"about_ca_system_score_codex":0.000050031136,"about_ca_system_score_gemma":0.00016463218,"threshold_uncertainty_score":0.99973625},"labels":[],"label_agreement":null},{"id":"W3136285030","doi":"10.1038/s41598-021-94171-y","title":"Targeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"Consejo Nacional de Ciencia y Tecnología","keywords":"Medicine; Internal medicine; Receiver operating characteristic; Metabolomics; Area under the curve; Metabolite; Coronavirus disease 2019 (COVID-19); Disease; Real-time polymerase chain reaction; Bioinformatics; Biology; Infectious disease (medical specialty)","score_opus":0.027075926848977448,"score_gpt":0.2761550358793007,"score_spread":0.24907910903032324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136285030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885234,0.0010468308,0.0011184423,0.0009296569,0.0072307093,0.00079985766,0.000030043768,0.00015654645,0.00016450594],"genre_scores_gemma":[0.9959612,0.000055539134,0.0009975424,0.0005456182,0.000049173934,0.00012473238,0.000076909535,0.000026316013,0.0021629818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971194,0.00010324891,0.0004934951,0.0013505834,0.0004399187,0.00049330737],"domain_scores_gemma":[0.9971551,0.0015331048,0.00025487077,0.0006099871,0.0001302326,0.00031673783],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0010168209,0.00020299635,0.00025030342,0.0002039094,0.0009788603,0.0007586302,0.00015918529,0.000078455676,0.00014914594],"category_scores_gemma":[0.03731859,0.00019101972,0.00011621981,0.00081103056,0.0006531117,0.00035134124,0.00016297364,0.00009189807,0.000011102175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029603481,0.00017712882,0.007325983,0.0003280577,0.000035446334,0.0015799232,0.0008708015,0.00008702815,0.9622874,0.0014491508,0.022262938,0.0035664944],"study_design_scores_gemma":[0.0006446491,0.000037495964,0.0043071974,0.000041083156,0.0000700732,0.0009720443,0.00075322174,0.0005082785,0.8878276,0.04210713,0.06225998,0.00047124777],"about_ca_topic_score_codex":0.000018486466,"about_ca_topic_score_gemma":0.00004551698,"teacher_disagreement_score":0.07445985,"about_ca_system_score_codex":0.000045062312,"about_ca_system_score_gemma":0.00052321586,"threshold_uncertainty_score":0.9707905},"labels":[],"label_agreement":null},{"id":"W3136668322","doi":"10.1016/j.biopsych.2021.03.017","title":"Early or Late Gestational Exposure to Maternal Immune Activation Alters Neurodevelopmental Trajectories in Mice: An Integrated Neuroimaging, Behavioral, and Transcriptional Study","year":2021,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":77,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; Jewish General Hospital; Montreal General Hospital; McGill University Health Centre; McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University","keywords":"Psychology; Neuroscience; Hippocampus; Offspring; Neuroimaging; Neurodevelopmental disorder; Striatum; Internal medicine; Endocrinology; Biology; Autism; Medicine; Pregnancy; Developmental psychology","score_opus":0.05201827152513249,"score_gpt":0.30578125780133797,"score_spread":0.25376298627620547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136668322","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981012,0.0000229606,0.00006029423,0.0008765599,0.00048098684,0.0003139846,0.000059333255,0.00006764848,0.00001707123],"genre_scores_gemma":[0.99743634,0.000012637821,0.001047448,0.0012959084,0.00003711213,0.000031552947,0.000040101437,0.0000132581445,0.00008563238],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99840105,0.00027030468,0.00030749134,0.00059228664,0.00019221575,0.00023664189],"domain_scores_gemma":[0.99967617,0.000046220066,0.00005101572,0.000099018136,0.00002933082,0.00009823903],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008556489,0.00018795588,0.00016420145,0.00009877573,0.00012243542,0.000112218026,0.00016251545,0.00006646584,0.00015977948],"category_scores_gemma":[0.00006503437,0.00014400555,0.000033629876,0.0003818257,0.00009329025,0.0002574293,0.000037843613,0.00022345637,0.0000068498243],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006924124,0.0013827789,0.33034623,0.0000056729386,0.000004052074,0.000042962434,0.0013855716,0.00002328794,0.6635141,0.00030037586,0.000028322986,0.002274279],"study_design_scores_gemma":[0.0011038264,0.0010205399,0.99116147,0.000015088431,0.0000026167706,0.000024818817,0.0011080062,0.000010293569,0.005101693,0.00017077415,0.00009025934,0.00019062626],"about_ca_topic_score_codex":0.00011075033,"about_ca_topic_score_gemma":0.00013282709,"teacher_disagreement_score":0.66081524,"about_ca_system_score_codex":0.000023537428,"about_ca_system_score_gemma":0.00009283976,"threshold_uncertainty_score":0.5872376},"labels":[],"label_agreement":null},{"id":"W3136939712","doi":"10.1002/cmdc.202100107","title":"A Series of 2‐((1‐Phenyl‐1H‐imidazol‐5‐yl)methyl)‐1H‐indoles as Indoleamine 2,3‐Dioxygenase 1 (IDO1) Inhibitors","year":2021,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Krembil Foundation; University Health Network","funders":"Canadian Institutes of Health Research; Krembil Foundation","keywords":"Chemistry; Penetrant (biochemical); Indoleamine 2,3-dioxygenase; Docking (animal); Pharmacology; Indole test; Stereochemistry; Structure–activity relationship; Combinatorial chemistry; Biochemistry; Medicine; In vitro; Tryptophan; Organic chemistry; Amino acid","score_opus":0.02542026926379457,"score_gpt":0.2527000280994199,"score_spread":0.22727975883562532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136939712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97899896,0.0007277532,0.000026899332,0.0015095841,0.0004570962,0.0002678315,0.00004821157,0.00021157414,0.017752105],"genre_scores_gemma":[0.99373233,0.00019213145,0.00045136924,0.0014027506,0.0002817054,0.000044623717,0.000023772685,0.00007684406,0.0037944983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99688035,0.00014738162,0.0006488657,0.0009292993,0.0006892586,0.00070481416],"domain_scores_gemma":[0.99806917,0.0003528863,0.00028380007,0.00082752143,0.00016353937,0.00030310338],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021444843,0.00045483006,0.0005944695,0.00017214651,0.00017118371,0.00008829617,0.0005579281,0.0002571725,0.0006698966],"category_scores_gemma":[0.002545482,0.00044917452,0.00030982078,0.0011754989,0.0006089524,0.0003967873,0.0003733121,0.0003735341,0.00020258955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011490851,0.00031239417,0.00017462653,0.00019227028,0.000022599597,0.00017184611,0.0010317952,0.000007844992,0.98823273,0.0024888425,0.004006911,0.003243259],"study_design_scores_gemma":[0.00135928,0.00009602055,0.0005610691,0.000112539645,0.000012330326,0.00012274602,0.0015945687,0.000014518995,0.98494864,0.0024702302,0.008235528,0.00047254964],"about_ca_topic_score_codex":0.0000217652,"about_ca_topic_score_gemma":0.000030203595,"teacher_disagreement_score":0.014733359,"about_ca_system_score_codex":0.00006917964,"about_ca_system_score_gemma":0.00034885373,"threshold_uncertainty_score":0.999796},"labels":[],"label_agreement":null},{"id":"W3137377805","doi":"10.1016/b978-0-12-817935-2.00009-x","title":"Linking depression, mRNA translation, and serotonin","year":2021,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University Health Centre; Carleton University","funders":"","keywords":"Major depressive disorder; MAPK/ERK pathway; Neuroscience; Kinase; Signal transduction; Serotonergic; Translation (biology); Prefrontal cortex; Serotonin; Psychology; Biology; Endocrinology; Messenger RNA; Internal medicine; Medicine; Receptor; Cell biology; Gene; Genetics; Cognition","score_opus":0.03158702706704737,"score_gpt":0.25267410563971293,"score_spread":0.22108707857266557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3137377805","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041002434,0.0046529397,0.000012663213,0.00011697656,0.00024978776,0.00048116344,0.00002077506,0.0001094199,0.99394625],"genre_scores_gemma":[0.00802834,0.000569841,0.00033181958,0.0015044064,0.00018826721,0.000028969856,0.00001451986,0.000099521356,0.9892343],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99825615,0.000050822146,0.00033941277,0.00074746046,0.00034354455,0.00026262054],"domain_scores_gemma":[0.9990958,0.00017149273,0.00015799719,0.0003976979,0.000050785813,0.00012624466],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010045658,0.00036050606,0.0003643911,0.00011449307,0.00021472822,0.000116606345,0.00022930955,0.0003236216,0.00030435648],"category_scores_gemma":[0.00005379032,0.0003435569,0.00012762623,0.000024755958,0.00018340771,0.000063014864,0.00010341763,0.00048785345,0.000053451935],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008779236,0.000005070813,0.000014024111,0.000084912645,0.00000888108,0.000058380752,0.00030093742,6.189463e-7,0.004867524,0.0030766048,0.000039245893,0.991535],"study_design_scores_gemma":[0.00040931438,0.000018225415,0.000035108176,0.0006215147,0.000025850508,0.000051596657,0.000007837603,0.000021071872,0.011528006,0.008444021,0.978409,0.00042843822],"about_ca_topic_score_codex":1.5185012e-7,"about_ca_topic_score_gemma":0.0000124175585,"teacher_disagreement_score":0.99110657,"about_ca_system_score_codex":0.000018263812,"about_ca_system_score_gemma":0.00010225604,"threshold_uncertainty_score":0.99990165},"labels":[],"label_agreement":null},{"id":"W3137975801","doi":"10.1093/schizbullopen/sgab006","title":"Glutathione Levels and Glutathione-Glutamate Correlation in Patients With Treatment-Resistant Schizophrenia","year":2021,"lang":"en","type":"article","venue":"Schizophrenia Bulletin Open","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Ontario Mental Health Foundation","keywords":"GCLC; Glutathione; GCLM; Glutamatergic; Glutamate receptor; Internal medicine; Endocrinology; Glutamine; Anterior cingulate cortex; Medicine; Pharmacology; Chemistry; Biochemistry; Psychiatry; Receptor; Amino acid","score_opus":0.019304719961123085,"score_gpt":0.2449011105810741,"score_spread":0.22559639061995101,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3137975801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932577,0.00018980994,0.00005118297,0.0019568787,0.00019344805,0.0010766124,0.00015261346,0.00009536457,0.003026396],"genre_scores_gemma":[0.99400985,0.00005869473,0.0034912112,0.00061311014,0.000038392755,0.00009220534,0.00005642082,0.000065619504,0.001574521],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9969412,0.00039062588,0.000497922,0.0011366567,0.0004667226,0.0005668384],"domain_scores_gemma":[0.998652,0.00027539555,0.00021621965,0.00054968864,0.000089815345,0.00021689321],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020581021,0.00044240258,0.0005085912,0.00018233506,0.00038647358,0.0005155876,0.00046138014,0.00015008086,0.0007852324],"category_scores_gemma":[0.00039301676,0.0003717778,0.00006504207,0.00066803547,0.00020276607,0.00033960844,0.00040084415,0.00029101572,0.0003397322],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.17626928,0.01832598,0.13666557,0.0006727939,0.0006423929,0.0046355547,0.01058018,0.003117304,0.18696512,0.12156833,0.01120745,0.32935002],"study_design_scores_gemma":[0.06799885,0.001745186,0.8722759,0.00054497557,0.000081534105,0.000078792684,0.00045949014,0.00041136646,0.030437494,0.004172094,0.019883154,0.0019112016],"about_ca_topic_score_codex":0.00012298053,"about_ca_topic_score_gemma":0.0003186445,"teacher_disagreement_score":0.7356103,"about_ca_system_score_codex":0.00013073071,"about_ca_system_score_gemma":0.00025922986,"threshold_uncertainty_score":0.9998734},"labels":[],"label_agreement":null},{"id":"W3138656299","doi":"10.1007/s00406-021-01237-z","title":"Increased peripheral inflammation in schizophrenia is associated with worse cognitive performance and related cortical thickness reductions","year":2021,"lang":"en","type":"article","venue":"European Archives of Psychiatry and Clinical Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Australian Schizophrenia Research Bank","keywords":"Schizophrenia (object-oriented programming); Inflammation; Neuropathology; Psychosis; Biomarker; Peripheral; Medicine; Psychology; Cognition; Effects of sleep deprivation on cognitive performance; Internal medicine; Psychiatry; Disease","score_opus":0.021556661455748322,"score_gpt":0.2794202585427501,"score_spread":0.2578635970870018,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138656299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99328613,0.000051991225,0.000063341184,0.00079507084,0.0003126129,0.00015548152,0.0000163962,0.00004273363,0.00527624],"genre_scores_gemma":[0.998126,0.0005460128,0.00030994107,0.0007515957,0.00003618963,0.0000023513026,0.0000031900327,0.000016771211,0.00020797146],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9969998,0.0012243614,0.0005673129,0.0007219353,0.00022568688,0.00026089072],"domain_scores_gemma":[0.9985892,0.0008114916,0.00020818246,0.00019017921,0.00002791468,0.00017301194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040036585,0.00016774514,0.00024136897,0.00009371839,0.00027705604,0.00006405614,0.00018533485,0.000042335905,0.000021203821],"category_scores_gemma":[0.0027171928,0.000146051,0.00005866577,0.00063503237,0.0019688532,0.00027309536,0.00014399554,0.00058353477,0.0000032144994],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037014403,0.0033651064,0.6885917,0.0002360206,0.000040149356,0.00041446838,0.0038622974,0.00010840927,0.23693682,0.00953238,0.000068604735,0.05314256],"study_design_scores_gemma":[0.002505941,0.00046770583,0.99034107,0.0003707899,0.000018487197,0.00011498506,0.00026666533,0.0032184895,0.001900053,0.0005744199,0.000023155353,0.00019823569],"about_ca_topic_score_codex":0.000001934164,"about_ca_topic_score_gemma":0.000020731937,"teacher_disagreement_score":0.30174932,"about_ca_system_score_codex":0.000002969672,"about_ca_system_score_gemma":0.00014618879,"threshold_uncertainty_score":0.72543216},"labels":[],"label_agreement":null},{"id":"W3139127871","doi":"10.1177/11786469211003109","title":"Lack of Skeletal Muscle Serotonin Impairs Physical Performance","year":2021,"lang":"en","type":"article","venue":"International Journal of Tryptophan Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Agence Nationale de la Recherche","keywords":"Serotonin; Endocrinology; Kynurenine; Internal medicine; Tryptophan; Skeletal muscle; Neurotransmitter; Peripheral; Medicine; Biology; Psychology; Central nervous system; Biochemistry; Amino acid","score_opus":0.1167722143575333,"score_gpt":0.4171735787290935,"score_spread":0.3004013643715602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139127871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99375767,0.0001003438,0.000056135174,0.0014922209,0.00047447695,0.000080631486,0.000014486962,0.000008978287,0.0040150858],"genre_scores_gemma":[0.9982689,0.00022171612,0.00025154004,0.00014988815,0.00045313023,0.0000035324247,0.0000015482748,0.000016703738,0.00063303206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99667567,0.00031043016,0.00043182867,0.0002279562,0.002033335,0.00032079118],"domain_scores_gemma":[0.9977025,0.0005366073,0.00021386638,0.00019283025,0.0012164074,0.00013778158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059664616,0.00011172116,0.00023146589,0.00034852713,0.0000783262,0.000084920495,0.00096644287,0.000054197175,0.00039753455],"category_scores_gemma":[0.0013227954,0.00009712827,0.000228345,0.00050554436,0.00031446735,0.00037203048,0.0002421639,0.0006004128,0.00006633461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019155302,0.0008631891,0.0010379748,0.000042900378,0.000051459567,0.00048606386,0.00069412333,0.00018803688,0.96105766,0.003509382,0.0013063175,0.03057134],"study_design_scores_gemma":[0.0012926927,0.00034663177,0.020786649,0.00011109259,0.0000029089144,0.00025721794,0.00040253083,0.0009579835,0.96833855,0.0018968347,0.0055004717,0.00010643375],"about_ca_topic_score_codex":0.000004573725,"about_ca_topic_score_gemma":0.0000021727362,"teacher_disagreement_score":0.030464904,"about_ca_system_score_codex":0.00009321578,"about_ca_system_score_gemma":0.00039659996,"threshold_uncertainty_score":0.43527246},"labels":[],"label_agreement":null},{"id":"W3139471760","doi":"10.1016/j.jpsychires.2021.03.013","title":"Peripheral metabolic state and immune system in first-episode psychosis – A gene expression study with a prospective one-year follow-up","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Sigrid Juséliuksen Säätiö; Suomen Kulttuurirahasto; Academy of Finland; Helsingin ja Uudenmaan Sairaanhoitopiiri; Helsingin Yliopisto","keywords":"Immune system; Internal medicine; Endocrinology; Biology; Gene expression; Cholesterol; Gene; Immunology; Medicine; Genetics","score_opus":0.03702018662055207,"score_gpt":0.3286103727799315,"score_spread":0.2915901861593794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139471760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942991,0.0032813658,0.00012284411,0.0005368894,0.00032304987,0.00072039576,0.0000054695633,0.000011718124,0.0006991281],"genre_scores_gemma":[0.9969842,0.00085578987,0.0015033421,0.000021463396,0.00012615285,0.00004993456,1.7420706e-7,0.00003269048,0.0004262969],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9959044,0.0009807259,0.00062089297,0.0005040431,0.0014653099,0.0005246142],"domain_scores_gemma":[0.998565,0.00024539616,0.00025895113,0.0003589543,0.0003727792,0.00019890499],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001463946,0.00018638303,0.0004877825,0.00070354866,0.0003056738,0.0002193031,0.00040227993,0.000059452323,0.000048583333],"category_scores_gemma":[0.00033395147,0.00013734985,0.00010973699,0.002332521,0.0001135467,0.00027963286,0.00013579683,0.00086716504,0.000008643227],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010833127,0.0054211696,0.84095126,0.00042315363,0.00021252055,0.0010963244,0.013042662,0.00020682081,0.122635394,0.0009904624,0.0012114439,0.0029756795],"study_design_scores_gemma":[0.029883647,0.005719604,0.80525583,0.0005589997,0.00006497692,0.0005383272,0.02466189,0.00016723131,0.1306619,0.0012100458,0.0006823187,0.0005952273],"about_ca_topic_score_codex":0.00016206587,"about_ca_topic_score_gemma":0.0006143492,"teacher_disagreement_score":0.03569542,"about_ca_system_score_codex":0.000119666256,"about_ca_system_score_gemma":0.0001831557,"threshold_uncertainty_score":0.56009644},"labels":[],"label_agreement":null},{"id":"W3144026814","doi":"10.1111/bph.15475","title":"Metabolic phenotyping of opioid and psychostimulant addiction: A novel approach for biomarker discovery and biochemical understanding of the disorder","year":2021,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Medical Research Council Canada","keywords":"Metabolome; Metabolomics; Addiction; Biomarker discovery; Biomarker; Drugs of abuse; Drug discovery; Biology; Bioinformatics; Computational biology; Neuroscience; Medicine; Pharmacology; Genetics; Proteomics; Gene","score_opus":0.08849600096661539,"score_gpt":0.34849632842293804,"score_spread":0.2600003274563226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3144026814","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014040414,0.9851228,0.011979563,0.00004867196,0.00061201403,0.0005042389,0.000285499,0.0000033785302,0.000039804956],"genre_scores_gemma":[0.014589941,0.9846281,0.00046599164,0.00011487185,0.00013216666,0.000016340846,0.000006244006,0.00002847422,0.0000178905],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983163,0.00022989335,0.0007491478,0.00030590084,0.00018616661,0.00021260515],"domain_scores_gemma":[0.9983,0.00060394715,0.0009018166,0.00007155658,0.000059823742,0.00006283187],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029461604,0.00020425528,0.0011645035,0.00014591092,0.00011108525,0.000048891412,0.0002893314,0.00016156452,0.000018800874],"category_scores_gemma":[0.00027674867,0.00016551158,0.0004067606,0.00034549087,0.0005107407,0.00013575924,0.00014879393,0.0003528535,2.9811233e-8],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023771555,0.0012076619,0.000015302336,0.01382986,0.0011973943,0.000036953403,0.00018348375,0.000013962392,0.09796529,0.0016773044,0.0067221886,0.8769129],"study_design_scores_gemma":[0.019464005,0.00042228834,0.00025860503,0.031203883,0.008728858,0.028713062,0.00085549074,0.0015408957,0.019036839,0.00085512263,0.8872091,0.0017118418],"about_ca_topic_score_codex":0.000005106541,"about_ca_topic_score_gemma":8.803788e-7,"teacher_disagreement_score":0.8804869,"about_ca_system_score_codex":0.000028752173,"about_ca_system_score_gemma":0.00020276429,"threshold_uncertainty_score":0.67493665},"labels":[],"label_agreement":null},{"id":"W3147236940","doi":"10.1177/070674371005501117","title":"Antidepressant Pretreatment and Symptomatic Treatment in Interferon Treatment","year":2010,"lang":"en","type":"article","venue":"The Canadian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Antidepressant; Medicine; Psychiatry; Psychology; Psychotherapist; Anxiety","score_opus":0.01596369654384921,"score_gpt":0.2503667176953094,"score_spread":0.23440302115146017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3147236940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903661,0.0005411023,0.0000022063139,0.0066737295,0.0010770055,0.0002353096,0.000010237265,0.0000055401497,0.0010887479],"genre_scores_gemma":[0.9990769,0.00009608875,0.00026812492,0.00027350464,0.00011024365,0.0000074813292,2.955663e-7,0.000013331946,0.00015402038],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991039,0.000090324385,0.00027725106,0.0001523458,0.000104765655,0.00027143458],"domain_scores_gemma":[0.9992363,0.00008806802,0.00014013585,0.00022726721,0.000012609476,0.00029566057],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010996966,0.0001620116,0.00019380367,0.00020766145,0.00017081926,0.00008744154,0.00020557853,0.000052584655,0.00008924512],"category_scores_gemma":[0.00004393649,0.00009213563,0.00008191761,0.00013120129,0.00017536103,0.00009029754,0.000006658962,0.00016213718,0.000009938361],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033963408,0.001253838,0.85424864,0.000054262822,0.00021992062,0.00058257824,0.013667439,0.00013359633,0.0184441,0.038996037,0.0016381346,0.07042179],"study_design_scores_gemma":[0.016875401,0.011320634,0.82420576,0.00052586314,0.00029985583,0.0046258075,0.0032338118,0.0007114282,0.060335997,0.061710496,0.014972155,0.0011827858],"about_ca_topic_score_codex":0.008036217,"about_ca_topic_score_gemma":0.64150125,"teacher_disagreement_score":0.63346505,"about_ca_system_score_codex":0.00017571112,"about_ca_system_score_gemma":0.0009267466,"threshold_uncertainty_score":0.99856937},"labels":[],"label_agreement":null},{"id":"W3148790898","doi":"10.1016/j.bbi.2021.04.002","title":"Brain morphology is differentially impacted by peripheral cytokines in schizophrenia-spectrum disorder","year":2021,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Health and Medical Research Council; University of Melbourne; Royal Melbourne Hospital; National Alliance for Research on Schizophrenia and Depression; Brain and Behavior Research Foundation","keywords":"Schizophrenia (object-oriented programming); Brain morphometry; Inflammation; Psychosis; Cytokine; Psychology; Brain size; Peripheral; Medicine; Immunology; Internal medicine; Magnetic resonance imaging; Psychiatry","score_opus":0.017105009746496758,"score_gpt":0.26858926716757947,"score_spread":0.2514842574210827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3148790898","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99194527,0.00038239668,0.000064052445,0.006635795,0.00020551337,0.00026380952,0.00017769515,0.00009891743,0.00022654264],"genre_scores_gemma":[0.9943318,0.00015109015,0.00004679727,0.003704423,0.000027250328,0.00004523654,0.00007711584,0.000040001672,0.001576335],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99768597,0.0005571319,0.00037691652,0.00058955693,0.00021724086,0.000573181],"domain_scores_gemma":[0.9989428,0.00029485955,0.00008857187,0.0005020737,0.000027286025,0.0001444006],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014741647,0.0003247449,0.0003683907,0.00013499071,0.000304506,0.00015785193,0.0003371728,0.00019665307,0.0013682254],"category_scores_gemma":[0.0005720555,0.0003168487,0.000115564806,0.0005607734,0.00034240726,0.00023699396,0.00026190182,0.00053715735,0.000014091338],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013558558,0.00077454874,0.021348523,0.000012560244,0.0000047161357,0.0000843836,0.00065009407,4.8100867e-7,0.9660082,0.00023663456,0.0036968894,0.0070473803],"study_design_scores_gemma":[0.0044596884,0.00019430037,0.78465086,0.000023064184,0.000014507825,0.00016674632,0.00051782123,0.00003769638,0.2054102,0.00052964594,0.0034402593,0.0005552299],"about_ca_topic_score_codex":0.00063079764,"about_ca_topic_score_gemma":0.0006034982,"teacher_disagreement_score":0.7633023,"about_ca_system_score_codex":0.000041425577,"about_ca_system_score_gemma":0.00009239982,"threshold_uncertainty_score":0.99992836},"labels":[],"label_agreement":null},{"id":"W3151535151","doi":"10.3389/fimmu.2021.622537","title":"The Antidepressant Mirtazapine Rapidly Shifts Hepatic B Cell Populations and Functional Cytokine Signatures in the Mouse","year":2021,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Wenzel Family Foundation","keywords":"Mirtazapine; CXCR3; CXCL10; Chemokine; Cytokine; Proinflammatory cytokine; Immune system; Immunology; Biology; Chemistry; Chemokine receptor; Pharmacology; Endocrinology; Inflammation; Antidepressant","score_opus":0.016682849097498037,"score_gpt":0.2323293040127473,"score_spread":0.21564645491524925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3151535151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98197514,0.01119989,0.0005873488,0.0040214546,0.0010553545,0.00024465343,0.00001411143,0.000025751382,0.0008762829],"genre_scores_gemma":[0.9964829,0.0014369348,0.0004588811,0.0010263685,0.000023733313,0.00003577956,0.000010952159,0.000011152329,0.0005133037],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99856555,0.00047456854,0.00022757208,0.00030594633,0.00013709256,0.00028926038],"domain_scores_gemma":[0.99918187,0.0003279434,0.00006131518,0.00039696431,0.00001613826,0.000015790907],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018058116,0.00012343795,0.00015549117,0.00011813664,0.00024205321,0.00005561647,0.000326794,0.00009587349,0.000029912024],"category_scores_gemma":[0.00061163347,0.00008178887,0.000040619547,0.0004184396,0.0003324222,0.00008952129,0.000119707365,0.00037387176,0.000003639195],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007129034,0.0010406754,0.091519095,0.000053236367,0.000053320833,0.00033628382,0.0040950915,0.0018934482,0.7693572,0.030377548,0.089918785,0.010642398],"study_design_scores_gemma":[0.0031662711,0.00012364068,0.87246495,0.000021692505,0.000013602574,0.00003872067,0.0035898404,0.0021591263,0.065113574,0.023280285,0.029656228,0.00037206343],"about_ca_topic_score_codex":0.000043239874,"about_ca_topic_score_gemma":0.0002799307,"teacher_disagreement_score":0.78094584,"about_ca_system_score_codex":0.000023098688,"about_ca_system_score_gemma":0.000044603785,"threshold_uncertainty_score":0.33352533},"labels":[],"label_agreement":null},{"id":"W3154048578","doi":"10.1016/j.bbih.2021.100259","title":"Increased telomerase activity in major depressive disorder with melancholic features: Possible role of pro-inflammatory cytokines and the brain-derived neurotrophic factor","year":2021,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Dokuz Eylül Üniversitesi","keywords":"Telomerase; Brain-derived neurotrophic factor; Major depressive disorder; Neurotrophic factors; Depression (economics); Tumor necrosis factor alpha; Internal medicine; Proinflammatory cytokine; Medicine; Mechanism (biology); Melancholic depression; Endocrinology; Psychology; Interleukin 6; Inflammation; Dexamethasone; Amygdala; Biology; Receptor; Melancholia; Gene; Genetics","score_opus":0.0169630250471996,"score_gpt":0.27670254004952666,"score_spread":0.25973951500232706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3154048578","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918729,0.0010426015,0.000007251874,0.004978433,0.00005487921,0.0017362959,0.00013738355,0.00008530933,0.00008495336],"genre_scores_gemma":[0.9962163,0.00023234397,0.00006183692,0.003029951,0.000023474577,0.00027012083,0.000017948047,0.00005959714,0.000088425644],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.995379,0.002387851,0.0004632397,0.0006455608,0.00047038533,0.00065398484],"domain_scores_gemma":[0.99689466,0.0014583258,0.0004224382,0.0009073613,0.00009112028,0.00022607873],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004140576,0.00040263726,0.0006579636,0.0002308091,0.0006001348,0.00010872062,0.0004826759,0.00014158482,0.00005029549],"category_scores_gemma":[0.001327948,0.0002956954,0.00011764422,0.00084143935,0.00081167225,0.00034136002,0.0002679168,0.00093834894,0.000002547944],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016778845,0.0010682836,0.043254238,0.0002484808,0.000016500673,0.00011157117,0.0048437184,0.000009872317,0.93576425,0.00047732997,0.000050445717,0.012477422],"study_design_scores_gemma":[0.0073403073,0.00023932492,0.8415133,0.00011961826,0.000015265985,0.000107082575,0.00096075464,0.000022401622,0.14909472,0.00010321165,0.00018303655,0.00030102048],"about_ca_topic_score_codex":0.004202609,"about_ca_topic_score_gemma":0.004385048,"teacher_disagreement_score":0.798259,"about_ca_system_score_codex":0.00007498545,"about_ca_system_score_gemma":0.0008116718,"threshold_uncertainty_score":0.9999495},"labels":[],"label_agreement":null},{"id":"W3154354859","doi":"10.1007/s10571-021-01078-3","title":"Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine","year":2021,"lang":"en","type":"review","venue":"Cellular and Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"Phenelzine; Antidepressant; Neuroprotection; Pharmacology; Medicine; Psychology; Psychiatry; Neuroscience; Biology; Monoamine oxidase; Anxiety","score_opus":0.030699743802113058,"score_gpt":0.2758549648012881,"score_spread":0.24515522099917508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3154354859","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015927177,0.9817581,0.00007158418,0.000044523476,0.00063083245,0.0012954664,0.000031161268,0.000016141175,0.00022496683],"genre_scores_gemma":[0.045625743,0.9536365,0.000007892924,0.0005360939,0.000027855996,0.00003755541,0.00000479934,0.0000634663,0.00006007342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99579644,0.0024483292,0.00053380046,0.00073441654,0.00016953942,0.00031745483],"domain_scores_gemma":[0.99796957,0.0004684962,0.0006446497,0.00083252596,0.000040278308,0.000044478373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120927914,0.0004108571,0.0012708216,0.00006902757,0.000121773024,0.000015445421,0.00072595355,0.00023267989,0.000008242586],"category_scores_gemma":[0.001142916,0.00023088531,0.00086622464,0.00059929956,0.00060550804,0.00002017094,0.0009677627,0.00056626595,0.000001659383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000040846367,0.000094963034,0.0000028013267,0.014840231,0.000050773026,0.00011547255,0.000038050464,0.0000032858982,0.9072284,0.0020591067,0.000027796046,0.075535014],"study_design_scores_gemma":[0.00030411038,0.00008511404,0.000025019237,0.00527642,0.00030381733,0.0001601306,0.000004169238,0.000003861317,0.8976794,0.00011578732,0.0957892,0.000252985],"about_ca_topic_score_codex":0.00000906956,"about_ca_topic_score_gemma":7.765033e-7,"teacher_disagreement_score":0.0957614,"about_ca_system_score_codex":0.00000848032,"about_ca_system_score_gemma":0.00012734157,"threshold_uncertainty_score":0.94152296},"labels":[],"label_agreement":null},{"id":"W3154920549","doi":"10.2147/jir.s306315","title":"Diet-Related Inflammation is Associated with Major Depressive Disorder in Bahraini Adults: Results of a Case-Control Study Using the Dietary Inflammatory Index","year":2021,"lang":"en","type":"article","venue":"Journal of Inflammation Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Inflammation; Medicine; Major depressive disorder; Index (typography); Internal medicine; Gastroenterology","score_opus":0.039287555709969654,"score_gpt":0.32580899549669873,"score_spread":0.28652143978672906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3154920549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969683,0.00019366678,0.00008832105,0.0013805851,0.000085962856,0.0010337859,0.000029664474,0.000014988658,0.0002046861],"genre_scores_gemma":[0.9996672,0.000057079553,0.000027342865,0.000044073986,0.00008164024,0.000024506822,0.0000030232052,0.000029589055,0.00006551853],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9927595,0.0029177659,0.0016651911,0.00036289208,0.001823168,0.00047147844],"domain_scores_gemma":[0.9937121,0.002668285,0.0013253166,0.00043853465,0.0017401548,0.00011560883],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.003807931,0.00022416652,0.00045253334,0.0007730636,0.00038746733,0.00013749379,0.00045305298,0.00017773623,0.00007912867],"category_scores_gemma":[0.010122526,0.0001555473,0.0001340456,0.0021140324,0.0003405094,0.00080779457,0.00013754731,0.0012332303,0.0000040480554],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03611143,0.0032783668,0.25199875,0.0005641999,0.0015850058,0.03275283,0.14562462,0.080516584,0.4062644,0.0003244637,0.00044687465,0.04053246],"study_design_scores_gemma":[0.07131992,0.0034301733,0.6179165,0.0025901536,0.00019359977,0.0016367679,0.077429324,0.10071339,0.1221634,0.0016078266,0.00012603223,0.00087290397],"about_ca_topic_score_codex":0.00013542235,"about_ca_topic_score_gemma":0.0015419999,"teacher_disagreement_score":0.36591774,"about_ca_system_score_codex":0.00019725358,"about_ca_system_score_gemma":0.00062887114,"threshold_uncertainty_score":0.9982156},"labels":[],"label_agreement":null},{"id":"W3155693531","doi":"10.1111/ejn.15239","title":"Inflammation‐driven brain and gut barrier dysfunction in stress and mood disorders","year":2021,"lang":"en","type":"review","venue":"European Journal of Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada First Research Excellence Fund","keywords":"Inflammation; Mood disorders; Neuroscience; Mood; Psychology; Stress (linguistics); Medicine; Psychiatry; Immunology; Anxiety; Philosophy","score_opus":0.03514353613660649,"score_gpt":0.2838152262496562,"score_spread":0.24867169011304974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3155693531","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012828124,0.9812007,0.0003491295,0.00079146016,0.0015382932,0.00057929405,0.00004416787,0.000039694627,0.0026291243],"genre_scores_gemma":[0.012375213,0.98686767,0.0000602215,0.00026580488,0.0001251258,0.0000021413234,0.0000011533199,0.00005056217,0.0002521383],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959209,0.0017725549,0.00087393826,0.0006292182,0.0004731726,0.00033020333],"domain_scores_gemma":[0.99822325,0.00048304562,0.00077104004,0.0002576319,0.00003897544,0.00022606814],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007004134,0.00035034362,0.00075471017,0.00052140723,0.00017333406,0.00031427416,0.0005842657,0.000054466822,0.00001213442],"category_scores_gemma":[0.0030954396,0.0002892497,0.00017057883,0.0008460547,0.0004610725,0.0005842937,0.00029434255,0.00070761575,0.0000055818155],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009511041,0.00006865057,0.00007150084,0.0012835936,0.000003990165,0.0004592445,0.0003308422,0.00005775355,0.0064992136,0.00019717502,0.000106161446,0.9909124],"study_design_scores_gemma":[0.0012152176,0.00048213554,0.0068111992,0.007918711,0.00006540004,0.0014300469,0.00013968398,0.00015806727,0.000120507655,0.00006404195,0.9809174,0.0006776219],"about_ca_topic_score_codex":8.506749e-7,"about_ca_topic_score_gemma":0.000009851958,"teacher_disagreement_score":0.99023473,"about_ca_system_score_codex":0.000030844327,"about_ca_system_score_gemma":0.00017214082,"threshold_uncertainty_score":0.99995595},"labels":[],"label_agreement":null},{"id":"W3156753857","doi":"10.1016/j.biopsych.2021.04.004","title":"Macro- and Microscale Stress–Associated Alterations in Brain Structure: Translational Link With Depression","year":2021,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":66,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Johnson and Johnson; Yale New Haven Hospital; Avanir Pharmaceuticals; Centre for Addiction and Mental Health Foundation; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; National Alliance for Research on Schizophrenia and Depression; Boehringer Ingelheim; Teva Pharmaceutical Industries; Janssen Pharmaceuticals; Yale University; Campbell Family Mental Health Research Institute; Valeant Pharmaceuticals International; Merck; Brain and Behavior Research Foundation","keywords":"Neuroscience; Major depressive disorder; Neurochemical; Chronic stress; Psychology; Neuroimaging; Depression (economics); Medicine; Amygdala","score_opus":0.04373917272572259,"score_gpt":0.31834903849941143,"score_spread":0.27460986577368884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3156753857","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004407786,0.9929532,0.00005382791,0.0006792241,0.0003245605,0.000556721,0.00075736846,0.000060904484,0.00020640297],"genre_scores_gemma":[0.008585023,0.988468,0.0007885223,0.0009927935,0.0002171788,0.0000507228,0.0007631017,0.00003706759,0.00009759258],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977556,0.0005055988,0.00043107106,0.00084003474,0.00015846945,0.00030923405],"domain_scores_gemma":[0.9990487,0.00046006765,0.00018390482,0.00020021446,0.000014565224,0.00009254217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007790954,0.0003646219,0.00075945735,0.00010824901,0.00015297627,0.000086338034,0.0002336139,0.0005623945,0.00017285736],"category_scores_gemma":[0.00020762111,0.00022874982,0.00016074245,0.0005121498,0.00019410424,0.00005831505,0.0000564037,0.0005812669,0.000004751082],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012272077,0.0011285888,0.017906196,0.0034152903,0.000110209614,0.000085837564,0.00017894604,0.000020480004,0.0017431602,0.008977072,0.0028876485,0.96342385],"study_design_scores_gemma":[0.0050782664,0.0006661251,0.03192276,0.021503435,0.00022032886,0.00033947735,0.000104467385,0.00006724773,0.00026503202,0.009703785,0.92680484,0.0033242444],"about_ca_topic_score_codex":0.0000047460885,"about_ca_topic_score_gemma":0.00020334007,"teacher_disagreement_score":0.9600996,"about_ca_system_score_codex":0.000021071888,"about_ca_system_score_gemma":0.0001854862,"threshold_uncertainty_score":0.9328147},"labels":[],"label_agreement":null},{"id":"W3157204177","doi":"10.64719/pb.4393","title":"Impact of the Omics-Based Biomarkers on the Fluvoxamine’s Steady-State Concentration, Efficacy and Safety in Patients with Affective Disorders Comorbid with Alcohol Use Disorder","year":2025,"lang":"en","type":"article","venue":"Psychopharmacology Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health","funders":"","keywords":"Fluvoxamine; CYP2D6; CYP2C19; Medicine; Pharmacology; Adverse effect; Internal medicine; Major depressive disorder; CYP3A; Fluoxetine; Cytochrome P450; Metabolism","score_opus":0.00923668582450255,"score_gpt":0.2730823641946961,"score_spread":0.26384567837019357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3157204177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915263,0.000025125688,0.00006601128,0.00539041,0.00016986801,0.002181218,0.000077701305,0.000027939092,0.00053541985],"genre_scores_gemma":[0.9969194,0.00004414703,0.000016327449,0.0028344723,0.000004221298,0.00008151794,0.0000058188707,0.00002306703,0.00007100774],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99797475,0.0006845079,0.0002663802,0.0005081293,0.00020906831,0.0003571539],"domain_scores_gemma":[0.9975831,0.0017994692,0.00019246299,0.00031850976,0.000051419767,0.000055027194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017505731,0.0002845658,0.00024591878,0.000111632275,0.00022335915,0.00003485555,0.0003302753,0.00006459461,0.00012583037],"category_scores_gemma":[0.00023051239,0.00014849097,0.000067788635,0.0006790609,0.000974717,0.000049595386,0.000046730962,0.00031852452,0.000005484991],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024503626,0.002112184,0.9530928,0.000030051338,0.00020643839,0.0000029237494,0.0005237647,0.0041157254,0.007230516,0.00021823493,0.0045901947,0.003373541],"study_design_scores_gemma":[0.020917596,0.0007193979,0.97454935,0.000060151375,0.000029986082,3.799084e-7,0.00005119373,0.00024195321,0.0022383058,0.000035856734,0.00096771854,0.00018809848],"about_ca_topic_score_codex":0.0001316892,"about_ca_topic_score_gemma":0.00013798407,"teacher_disagreement_score":0.021456562,"about_ca_system_score_codex":0.00007686431,"about_ca_system_score_gemma":0.00011029095,"threshold_uncertainty_score":0.6055286},"labels":[],"label_agreement":null},{"id":"W3158197537","doi":"10.26685/urncst.224","title":"The Effect of Exercise on Reducing Tumor Necrosis Factor Alpha Levels and Attenuating Serotonin Transporter Gene Expression: A Research Protocol","year":2021,"lang":"en","type":"article","venue":"Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Serotonin transporter; Tumor necrosis factor alpha; Serotonin; Endocrinology; Internal medicine; Cytokine; Medicine; Inflammation; p38 mitogen-activated protein kinases; Stimulation; Hippocampus; Reuptake; Open field; MAPK/ERK pathway; Pharmacology; Kinase; Biology; Receptor; Cell biology","score_opus":0.10422366804347385,"score_gpt":0.44540724947384336,"score_spread":0.34118358143036953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158197537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9763622,0.0003873746,0.0000023373598,0.018020796,0.00009114414,0.005022626,0.0000031133934,0.000019734967,0.000090655805],"genre_scores_gemma":[0.997837,0.0008215837,0.00017085679,0.00004794864,0.000038670187,0.0009100638,1.2053906e-7,0.000010803838,0.00016294468],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9947212,0.001102087,0.0006760485,0.0008701683,0.0015807145,0.0010497828],"domain_scores_gemma":[0.9949811,0.0037759906,0.00016385106,0.000323519,0.00044905258,0.00030646595],"candidate_categories":["sts","research_integrity"],"consensus_categories":["sts"],"category_scores_codex":[0.010031595,0.00018982733,0.00038627206,0.0006222648,0.0021941664,0.00040510672,0.0007079001,0.00018777615,0.000009601159],"category_scores_gemma":[0.0076138577,0.00010556359,0.00006533538,0.0029773188,0.006492368,0.00035720808,0.0005133801,0.0033890246,0.0000028711995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067198166,0.0001823565,0.025174992,0.00013365078,0.0000087811095,0.00039021953,0.00014780022,0.0000010660567,0.7507492,0.0008085757,0.00014113875,0.22159028],"study_design_scores_gemma":[0.0031890047,0.0022202965,0.019177591,0.0013555448,0.0000043780415,0.0004318594,0.0004509598,0.00061302865,0.9487674,0.023175959,0.0003927664,0.00022117443],"about_ca_topic_score_codex":0.000016740249,"about_ca_topic_score_gemma":0.00001802557,"teacher_disagreement_score":0.2213691,"about_ca_system_score_codex":0.000092380964,"about_ca_system_score_gemma":0.00059035694,"threshold_uncertainty_score":0.99910486},"labels":[],"label_agreement":null},{"id":"W3158338204","doi":"10.1016/j.jpsychires.2021.04.029","title":"Accelerated aging signatures in subjects with schizophrenia and their unaffected siblings","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul; Hospital de Clínicas de Porto Alegre; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Endophenotype; Proteostasis; Pathological; Schizophrenia (object-oriented programming); Oxidative stress; TBARS; Biomarker; Medicine; Internal medicine; Thiobarbituric acid; Psychology; Cognition; Psychiatry; Biology; Lipid peroxidation; Biochemistry","score_opus":0.05457999938422255,"score_gpt":0.34451919028296396,"score_spread":0.28993919089874143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158338204","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99151015,0.0026449698,0.00003990772,0.0017024368,0.000102969105,0.00012181597,9.578845e-7,0.000013691606,0.003863119],"genre_scores_gemma":[0.99811876,0.0006346451,0.00056920276,0.00013261434,0.00011847801,0.0000016596151,1.6879724e-7,0.000027029071,0.00039746024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980208,0.0005443839,0.0002571217,0.00026259702,0.0005449926,0.0003700959],"domain_scores_gemma":[0.9987403,0.000632654,0.00012291397,0.00014685269,0.00021800368,0.0001392597],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074280374,0.000118137425,0.00020843405,0.001149468,0.00012954735,0.000186545,0.00026747625,0.000072033545,0.00012277733],"category_scores_gemma":[0.0008212091,0.00007808837,0.000044102537,0.0038714581,0.00012196094,0.00016494138,0.00006737351,0.0009860169,0.0000044766716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019621595,0.0006538599,0.016543722,0.00016612529,0.000041267947,0.0013976393,0.0013610733,0.00026360113,0.94646823,0.0021621592,0.00751541,0.021464758],"study_design_scores_gemma":[0.019057555,0.002128132,0.20021826,0.0006057206,0.000016022344,0.001082958,0.0041056713,0.0011703251,0.7566691,0.010497035,0.0037107177,0.0007385012],"about_ca_topic_score_codex":0.000013181086,"about_ca_topic_score_gemma":0.000076447985,"teacher_disagreement_score":0.18979913,"about_ca_system_score_codex":0.000027940174,"about_ca_system_score_gemma":0.00039221204,"threshold_uncertainty_score":0.42838076},"labels":[],"label_agreement":null},{"id":"W3158593111","doi":"10.1038/s41380-021-01110-4","title":"Neuromodulatory effect of interleukin 1β in the dorsal raphe nucleus on individual differences in aggression","year":2021,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Japan Society for the Promotion of Science; National Institutes of Health; Ministry of Education, Culture, Sports, Science and Technology; National Institute of Mental Health; U.S. Department of Health and Human Services","keywords":"Dorsal raphe nucleus; Aggression; Neuroscience; Serotonergic; Psychology; Raphe nuclei; Serotonin; Forebrain; Receptor; Internal medicine; Central nervous system; Medicine; Psychiatry","score_opus":0.013814670892081181,"score_gpt":0.2537894090708528,"score_spread":0.2399747381787716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158593111","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99692523,0.00062729325,0.000011022589,0.00078843895,0.00066013774,0.00022270271,0.000007651047,0.000020591855,0.00073691143],"genre_scores_gemma":[0.9976922,0.000028691476,0.000031013817,0.0021833014,0.000019055815,0.00001780144,0.00000301787,0.000018232704,0.0000066519588],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974274,0.0011390514,0.00027434962,0.00045238037,0.0004442414,0.00026254565],"domain_scores_gemma":[0.999186,0.00025945166,0.00009871353,0.00041786092,0.000006865095,0.000031114494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026714033,0.00019090083,0.00023458252,0.00018935991,0.0000439579,0.00004211992,0.0005314024,0.000080656704,0.00003712233],"category_scores_gemma":[0.0002899478,0.00013191503,0.00012615471,0.0006771126,0.000114143404,0.000051187017,0.00009512752,0.00039740984,0.000011480169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007212551,0.0024899358,0.2271051,0.00030881568,0.000027886528,0.0016025087,0.003088335,0.00017687697,0.7269618,0.009375115,0.0009790938,0.027163308],"study_design_scores_gemma":[0.0038492808,0.0010908901,0.45638618,0.00082594244,0.000016072567,0.000059937345,0.0004661026,0.0001645572,0.5331639,0.0034013523,0.00017178802,0.00040399437],"about_ca_topic_score_codex":0.000011589561,"about_ca_topic_score_gemma":0.000042496544,"teacher_disagreement_score":0.2292811,"about_ca_system_score_codex":0.000010688841,"about_ca_system_score_gemma":0.000058913658,"threshold_uncertainty_score":0.5379339},"labels":[],"label_agreement":null},{"id":"W3158736480","doi":"10.1212/wnl.94.15_supplement.2745","title":"Alzheimer’s Disease as a Disorder of Tryptophan Metabolism (2745)","year":2020,"lang":"en","type":"article","venue":"Neurology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Krembil Foundation; University Health Network","funders":"","keywords":"Disease; Tryptophan Metabolism; Tryptophan; Physiology; Medicine; Psychiatry; Biology; Internal medicine; Genetics; Amino acid","score_opus":0.03430982676713226,"score_gpt":0.2682278057543429,"score_spread":0.23391797898721065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158736480","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9768418,0.00080529624,0.00008964197,0.018229827,0.00031072425,0.00026835428,0.00003109342,0.00013676894,0.0032865012],"genre_scores_gemma":[0.9623601,0.00009813787,0.000020647822,0.037342075,0.00010087704,0.000018795317,0.0000025014801,0.00002881092,0.000028073086],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99842715,0.00021900701,0.00024565158,0.00054911,0.00022198027,0.00033709902],"domain_scores_gemma":[0.9991096,0.00018644253,0.000102459046,0.00028053115,0.000019135347,0.00030182334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000033138796,0.00018096543,0.00027659177,0.00006608712,0.00006668074,0.000013327392,0.00041163282,0.00007767558,0.00059768144],"category_scores_gemma":[0.0006723221,0.00016609076,0.00013176384,0.0003448623,0.00027174567,0.00009907084,0.00013539115,0.00022359678,0.00027040637],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010141326,0.001500717,0.007867521,0.00013791828,0.000101589234,0.0009978982,0.002927272,0.0006596775,0.78448045,0.14707254,0.008186416,0.035926666],"study_design_scores_gemma":[0.008199533,0.0030562738,0.11514114,0.000008071759,0.00022597873,0.000070509006,0.00006214526,0.003658095,0.2774962,0.018947128,0.57193536,0.0011995917],"about_ca_topic_score_codex":0.000026637474,"about_ca_topic_score_gemma":0.000004544918,"teacher_disagreement_score":0.56374896,"about_ca_system_score_codex":9.950785e-7,"about_ca_system_score_gemma":0.00006186403,"threshold_uncertainty_score":0.6772984},"labels":[],"label_agreement":null},{"id":"W3158922629","doi":"10.3389/fphar.2021.676239","title":"Monoamine Oxidase Inhibitors: A Review of Their Anti-Inflammatory Therapeutic Potential and Mechanisms of Action","year":2021,"lang":"en","type":"review","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Monoamine oxidase; Inflammation; Pharmacology; Monoamine oxidase A; Mechanism of action; Chemokine; Monoamine neurotransmitter; Medicine; Central nervous system; Serotonin; Immunology; Biology; In vitro; Enzyme; Receptor; Biochemistry; Internal medicine","score_opus":0.03743712006276152,"score_gpt":0.32846522810606477,"score_spread":0.29102810804330326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158922629","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00028275562,0.99470305,0.001156896,0.00006105127,0.002614301,0.0010623976,0.000054410455,0.000023418006,0.00004170018],"genre_scores_gemma":[0.0009941114,0.99805397,0.00020217709,0.00047531057,0.000083539824,0.00009455274,0.000018545732,0.00004310133,0.00003470499],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99701554,0.001027933,0.00090765895,0.0005593494,0.0001910706,0.00029847934],"domain_scores_gemma":[0.99873644,0.00016017661,0.0007509842,0.00023988436,0.00004398579,0.00006852334],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035255123,0.00037670162,0.0020293456,0.00040864048,0.00003587115,0.0000072146568,0.00033598943,0.00028511643,0.00011890374],"category_scores_gemma":[0.000079650614,0.00032011184,0.00036822757,0.0005732572,0.00028398214,0.00010174632,0.00014999138,0.00043089283,0.0000016926291],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021894395,0.00022949956,0.0000023926443,0.084441066,0.00013710071,0.00007094817,0.000042186366,9.169697e-7,0.04601194,0.00018525917,0.005892737,0.86296403],"study_design_scores_gemma":[0.0016647485,0.00019852474,0.0000067512988,0.04363121,0.0010462718,0.0001616708,0.00014659703,0.00008331289,0.14096986,0.0008992002,0.8104655,0.0007263456],"about_ca_topic_score_codex":0.0000019943316,"about_ca_topic_score_gemma":3.6302652e-7,"teacher_disagreement_score":0.8622377,"about_ca_system_score_codex":0.000063244486,"about_ca_system_score_gemma":0.0002442085,"threshold_uncertainty_score":0.9999251},"labels":[],"label_agreement":null},{"id":"W3158923167","doi":"10.1007/s10539-021-09801-6","title":"Immunoceptive inference: why are psychiatric disorders and immune responses intertwined?","year":2021,"lang":"en","type":"article","venue":"Biology & Philosophy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Economic and Social Research Council; Medical Research Council; Social Sciences and Humanities Research Council of Canada; Wellcome Trust","keywords":"Schizophrenia (object-oriented programming); Inference; Immune system; Autism; Psychology; Neuroscience; Psychiatry; Cognitive science; Medicine; Immunology; Computer science; Artificial intelligence","score_opus":0.02910954230409067,"score_gpt":0.29038617484617146,"score_spread":0.2612766325420808,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158923167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96120316,0.0055971676,0.00018653028,0.020805433,0.000866943,0.0002460689,0.00008240173,0.00017376474,0.010838527],"genre_scores_gemma":[0.9924977,0.001383124,0.00012776646,0.0056082876,0.00013645273,0.000025563808,0.000013142721,0.000021593043,0.00018640941],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99822813,0.0003934428,0.0002784047,0.0006645211,0.000091957794,0.00034354939],"domain_scores_gemma":[0.99887073,0.0004944564,0.00013815679,0.0003842387,0.000046107172,0.00006630739],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000088657456,0.000247155,0.0002918411,0.00018414133,0.00022919285,0.000042683732,0.0002940994,0.0001720525,0.00019748704],"category_scores_gemma":[0.0009941356,0.0002184989,0.0001193468,0.00044509603,0.00058468326,0.0001297653,0.00025071457,0.0002745888,0.000078597055],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010213763,0.0007476613,0.035561092,0.000086123146,0.00008328236,0.00006297179,0.0010544434,0.0000019484223,0.80052775,0.14062189,0.0015898128,0.018641638],"study_design_scores_gemma":[0.0037725505,0.0010719966,0.14992628,0.00010771807,0.000043531083,0.000104960454,0.0007410322,0.000043541604,0.09464663,0.7052596,0.04303314,0.001248989],"about_ca_topic_score_codex":0.00001599276,"about_ca_topic_score_gemma":0.000014929399,"teacher_disagreement_score":0.7058811,"about_ca_system_score_codex":0.00001655199,"about_ca_system_score_gemma":0.00006747947,"threshold_uncertainty_score":0.89101267},"labels":[],"label_agreement":null},{"id":"W3159289477","doi":"10.1016/j.biopsych.2021.02.216","title":"Single-Cell Genomic Strategies to Understand Psychopathological Processes in Suicide and Associated Psychopathology","year":2021,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas College; University of British Columbia; McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Psychopathology; Psychology; Neuroscience; Clinical psychology","score_opus":0.06777237450498617,"score_gpt":0.293830608739669,"score_spread":0.2260582342346828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159289477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987053,0.0016574292,0.0002788738,0.0027522654,0.00055537524,0.00026693498,0.000028706203,0.00014612307,0.007261306],"genre_scores_gemma":[0.99230564,0.00036646027,0.0011701017,0.0059456225,0.000067357614,0.00001624267,0.000008784565,0.000017305794,0.00010247138],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99748784,0.00038877773,0.00038375723,0.0010310721,0.00014088508,0.00056767033],"domain_scores_gemma":[0.99914587,0.0003160713,0.000095738134,0.00023716573,0.000037563357,0.0001676033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001998755,0.00027606744,0.0003567109,0.00011683781,0.00012272997,0.00011790817,0.00027775974,0.00032915524,0.00012170926],"category_scores_gemma":[0.0009333004,0.00021888876,0.00006558617,0.00081524084,0.00028813005,0.00009743381,0.00012664267,0.00031657075,0.000053203225],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035793064,0.0023156523,0.08740434,0.000069097056,0.000004985577,0.00025311476,0.0006000232,0.000027626176,0.9004202,0.006329867,0.0010715114,0.0011456747],"study_design_scores_gemma":[0.0056856005,0.0030743345,0.8153563,0.00016185612,0.000016293274,0.00037195656,0.010761315,0.00001613875,0.020377068,0.13996257,0.0025793016,0.0016372595],"about_ca_topic_score_codex":0.000003355992,"about_ca_topic_score_gemma":0.00024484657,"teacher_disagreement_score":0.8800431,"about_ca_system_score_codex":0.000045281282,"about_ca_system_score_gemma":0.00016365029,"threshold_uncertainty_score":0.8926025},"labels":[],"label_agreement":null},{"id":"W3159733198","doi":"10.1016/j.biopsych.2021.02.704","title":"Counteracting Effect of Glutathione on the Glutamate-Driven Excitation/Inhibition Imbalance in First-Episode Schizophrenia: A 7T Mrs and Dynamic Causal Modeling Study","year":2021,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Glutamate receptor; Glutathione; Glutamatergic; NMDA receptor; Excitatory postsynaptic potential; Oxidative stress; Neuroscience; Chemistry; Schizophrenia (object-oriented programming); Psychotomimetic; Pharmacology; Biochemistry; Psychology; Biology; Receptor; Psychiatry","score_opus":0.0248697929975515,"score_gpt":0.2833493328611685,"score_spread":0.258479539863617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159733198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975156,0.00017948006,0.00015558074,0.0012264036,0.0003097302,0.0004503323,0.000016989938,0.000046508496,0.000099337776],"genre_scores_gemma":[0.999284,0.00006909446,0.00015691544,0.0003897626,0.000033752676,0.000046013203,0.0000054825414,0.000010526219,0.000004413141],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982467,0.0005145368,0.00033952048,0.000493952,0.0001817273,0.00022353954],"domain_scores_gemma":[0.99868315,0.0009421651,0.0001249014,0.00019018268,0.000021655254,0.00003791657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030991936,0.00017798074,0.0002493163,0.000059453283,0.0001797536,0.000039046587,0.000119917764,0.00009293179,0.00001981053],"category_scores_gemma":[0.00089706003,0.00011211356,0.00006260919,0.00032620635,0.000096072436,0.00007775609,0.00007091432,0.00029279865,0.000009775794],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044377213,0.0036892993,0.6029233,0.00034975636,0.00006292725,0.000159351,0.0020467236,0.017369103,0.35717604,0.009857181,0.00012990537,0.0017987416],"study_design_scores_gemma":[0.012329248,0.0053082393,0.6487189,0.0010145697,0.000045199507,0.00010257007,0.005354677,0.30231562,0.008632457,0.0150557235,0.00002293965,0.0010998764],"about_ca_topic_score_codex":0.000023209252,"about_ca_topic_score_gemma":0.00036413173,"teacher_disagreement_score":0.34854358,"about_ca_system_score_codex":0.000027714314,"about_ca_system_score_gemma":0.000020667649,"threshold_uncertainty_score":0.45718583},"labels":[],"label_agreement":null},{"id":"W3160338160","doi":"10.1093/ofid/ofab245","title":"Changes in Immune Activation During Pregnancy and the Postpartum Period in Treated HIV Infection","year":2021,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Mental Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Medicine; Pregnancy; Postpartum period; Biomarker; Kynurenine; Immunology; Cohort; Obstetrics; Internal medicine; Physiology; Tryptophan","score_opus":0.012252982576740285,"score_gpt":0.24816032973130495,"score_spread":0.23590734715456466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3160338160","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920385,0.00031918942,0.0000029362418,0.0026072524,0.00007825634,0.00069813867,0.000011690366,0.000057372785,0.0041866796],"genre_scores_gemma":[0.99830437,0.0007449041,9.124258e-7,0.00026107667,0.000010735092,0.00026394817,0.000013208677,0.000017009917,0.00038386055],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99884015,0.00025813802,0.0001713962,0.0003594939,0.0001067596,0.00026404342],"domain_scores_gemma":[0.9995221,0.00012836419,0.00007885992,0.00020552425,0.000020910698,0.000044236684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000048140166,0.00014493421,0.0001979751,0.00013248334,0.00025103742,0.00027485227,0.00012224285,0.00004703436,0.00009734918],"category_scores_gemma":[0.0005712353,0.000116881274,0.000042930667,0.00061785476,0.00011713305,0.0005006933,0.00023791571,0.00012288183,0.000009222767],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004114357,0.0006480263,0.94678116,0.00009030975,0.000010646329,0.00008437629,0.00077909144,0.00007705478,0.042365447,0.0031558545,0.000032195498,0.005564404],"study_design_scores_gemma":[0.0054627247,0.000055835095,0.90536267,0.00036468825,0.000008569817,0.000046367255,0.00035017863,0.00013016087,0.08635907,0.0015600577,0.00009948904,0.00020020644],"about_ca_topic_score_codex":0.0005206923,"about_ca_topic_score_gemma":0.00377188,"teacher_disagreement_score":0.043993622,"about_ca_system_score_codex":0.000069308604,"about_ca_system_score_gemma":0.00004903693,"threshold_uncertainty_score":0.476628},"labels":[],"label_agreement":null},{"id":"W3163942829","doi":"10.3389/fimmu.2021.667179","title":"Tryptophan Catabolites in Bipolar Disorder: A Meta-Analysis","year":2021,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Bipolar disorder; Meta-analysis; Mood; Medicine; Strictly standardized mean difference; Kynurenine; Internal medicine; Kynurenic acid; Subgroup analysis; Cerebrospinal fluid; PsycINFO; Psychiatry; Tryptophan; MEDLINE; Glutamate receptor; Biology","score_opus":0.0576218568800445,"score_gpt":0.31312502938019626,"score_spread":0.25550317250015175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163942829","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000023258548,0.9972908,0.00040487034,0.00008961633,0.0010280794,0.0006936617,0.00018161992,0.00006519967,0.00022291768],"genre_scores_gemma":[0.000023930552,0.9972361,0.00086789747,0.00018748108,0.000027938866,0.00047430865,0.0001913266,0.00007944411,0.0009115808],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.993623,0.0022372345,0.0013289284,0.0015737789,0.000273734,0.0009632893],"domain_scores_gemma":[0.9975864,0.0005346932,0.0004782056,0.001305601,0.00002464031,0.00007044443],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036923678,0.0008051974,0.007408854,0.0033934792,0.00009001763,0.00007808137,0.0014199342,0.00080956845,0.0005302056],"category_scores_gemma":[0.00092660903,0.0006920507,0.0033408818,0.0069125234,0.00044670803,0.00016590141,0.00037105914,0.0012698311,0.000065563574],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001563232,0.000556864,0.0002507789,0.0013519044,0.03622268,0.0003642778,0.00035082496,0.000019196903,0.000016258286,0.0017886037,0.0012302265,0.95783275],"study_design_scores_gemma":[0.0003347055,0.000025316524,0.00003178804,0.00012157081,0.027865337,0.000021437221,0.00015185114,0.000011829152,0.000028180866,0.00027634334,0.9705305,0.00060113886],"about_ca_topic_score_codex":0.00026482108,"about_ca_topic_score_gemma":0.00040567692,"teacher_disagreement_score":0.96930027,"about_ca_system_score_codex":0.00019592457,"about_ca_system_score_gemma":0.00035742708,"threshold_uncertainty_score":0.9995531},"labels":[],"label_agreement":null},{"id":"W3164107429","doi":"10.1016/j.bcp.2021.114617","title":"Hippocampal mitogen-activated protein kinase phosphatase-1 regulates behavioral and systemic effects of chronic corticosterone administration","year":2021,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; University of Toronto","funders":"Pharmaceutical Research and Manufacturers of America Foundation","keywords":"Corticosterone; Internal medicine; Endocrinology; Hippocampal formation; Chronic stress; Hippocampus; Systemic administration; Protein kinase A; Glucocorticoid; Psychology; Medicine; Kinase; Biology; Hormone","score_opus":0.017595478651070633,"score_gpt":0.2898719871310628,"score_spread":0.2722765084799922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164107429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99363637,0.005113395,0.000013515182,0.00013686238,0.00043867037,0.0005640605,0.00003211376,0.00005652883,0.000008475523],"genre_scores_gemma":[0.99942786,0.00008028055,0.000034283166,0.0001728817,0.00007666297,0.00008702469,0.00003624706,0.000017247901,0.000067516645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986526,0.00017612778,0.0002815161,0.0004583525,0.00014507496,0.00028635634],"domain_scores_gemma":[0.9993841,0.00014992534,0.00013723366,0.00014996398,0.00004268926,0.00013608359],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003847599,0.00017256195,0.00024700767,0.000039614686,0.0000535614,0.000016762313,0.00012435547,0.00014430567,0.00011993515],"category_scores_gemma":[0.00013597823,0.00017427716,0.000050352926,0.00021240208,0.0002982385,0.00007483239,0.00009294708,0.00015380335,0.000009139059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025338843,0.00044518392,0.000021390311,0.00036355617,0.000011274423,0.00014019445,0.000047360485,3.9752953e-7,0.9956816,0.000057358415,0.0020896434,0.00088868104],"study_design_scores_gemma":[0.0020794063,0.00042662674,0.00017808005,0.000074822594,0.000042911553,0.00009991338,0.000018312587,0.000044141667,0.99668354,0.00004375143,0.00014222358,0.00016625525],"about_ca_topic_score_codex":0.000004529728,"about_ca_topic_score_gemma":4.0495794e-7,"teacher_disagreement_score":0.005791477,"about_ca_system_score_codex":0.0000649154,"about_ca_system_score_gemma":0.00015580168,"threshold_uncertainty_score":0.7106816},"labels":[],"label_agreement":null},{"id":"W3164262966","doi":"","title":"Peripheral metabolic state and immune system in first-episode psychosis : A gene expression study with a prospective one-year follow-up","year":2021,"lang":"en","type":"article","venue":"STM:n Hallinnonalan avoin julkaisuarkisto (Julkari)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Immune system; Biology; Internal medicine; Endocrinology; Gene expression; Gene; Cholesterol; Immunology; Medicine; Genetics","score_opus":0.017154858434773393,"score_gpt":0.2504140030542181,"score_spread":0.23325914461944475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164262966","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99125504,0.0017792335,0.0004882778,0.0003080967,0.0004435979,0.0020653869,0.00011628866,0.00024655534,0.0032975215],"genre_scores_gemma":[0.9946683,0.00025389178,0.0013210622,0.00023524498,0.00010265039,0.0006021492,0.000020534015,0.00014229128,0.0026538852],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9942107,0.00071088783,0.00095059245,0.0020138153,0.0010881036,0.0010258565],"domain_scores_gemma":[0.99781096,0.0002952134,0.00035520512,0.0010155541,0.0002075765,0.0003155038],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057838525,0.00075855234,0.0011150821,0.0003685656,0.00054620684,0.0003337772,0.0005894061,0.00017625887,0.00017048248],"category_scores_gemma":[0.00022608235,0.0006844141,0.00019515274,0.0015350878,0.00032300898,0.0004523993,0.00032864715,0.0007732724,0.000078231715],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010272111,0.009839827,0.56763965,0.0010977789,0.0006226825,0.0027828137,0.032709006,0.0006224279,0.3607129,0.009769377,0.00068810466,0.0032433243],"study_design_scores_gemma":[0.035865843,0.0027547588,0.55843455,0.0014100862,0.00023925233,0.00040107127,0.013068472,0.0011970886,0.37624598,0.0014731813,0.0056025903,0.0033071274],"about_ca_topic_score_codex":0.0006597558,"about_ca_topic_score_gemma":0.006006658,"teacher_disagreement_score":0.025593733,"about_ca_system_score_codex":0.00024916354,"about_ca_system_score_gemma":0.00016876585,"threshold_uncertainty_score":0.9995607},"labels":[],"label_agreement":null},{"id":"W3164881339","doi":"10.1136/bmjgast-2020-000588","title":"Association between antidepressant medication use and steroid dependency in patients with ulcerative colitis: a population-based study","year":2021,"lang":"en","type":"article","venue":"BMJ Open Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Crohn's and Colitis UK; Wellcome Trust","keywords":"Medicine; Ulcerative colitis; Corticosteroid; Internal medicine; Antidepressant; Population; Tricyclic antidepressant; Logistic regression; Gastroenterology; Disease","score_opus":0.03131921360806472,"score_gpt":0.3044109533581574,"score_spread":0.27309173975009265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164881339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970713,9.276061e-7,0.00016085035,0.0006180092,0.000056097313,0.0019933183,0.00005644589,0.000015786176,0.000027257016],"genre_scores_gemma":[0.99852777,9.613644e-7,0.00017081792,0.00096987427,0.000013738093,0.00017693704,0.000087608154,0.000013010945,0.000039265262],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99754,0.0010387658,0.0003267538,0.00049876946,0.00031786278,0.00027783168],"domain_scores_gemma":[0.9990868,0.00027919555,0.00026123732,0.00022439483,0.00008256542,0.00006580854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028817856,0.00013114935,0.00027901217,0.00009291719,0.0000924654,0.00016080335,0.00019859137,0.000056889294,0.00004122219],"category_scores_gemma":[0.00072198675,0.00012117389,0.000015793645,0.00015087954,0.000026954836,0.00046704678,0.00016026008,0.00014075145,0.0000033703825],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065098295,0.0004574744,0.99830824,0.000006171552,0.00002061436,0.000018676588,0.00019970181,0.000022812808,0.000036834255,0.000009805516,0.00003380719,0.00023489987],"study_design_scores_gemma":[0.0066339234,0.0007349928,0.99209243,0.000028432944,0.000019398316,0.000001385673,0.00013626512,0.00005928048,0.00016394851,0.00004443442,0.000004749079,0.000080757745],"about_ca_topic_score_codex":0.00028227732,"about_ca_topic_score_gemma":0.007731212,"teacher_disagreement_score":0.0074489345,"about_ca_system_score_codex":0.00009079217,"about_ca_system_score_gemma":0.000056312998,"threshold_uncertainty_score":0.4941328},"labels":[],"label_agreement":null},{"id":"W3165869049","doi":"10.1038/s41398-021-01450-3","title":"A double-blind placebo-controlled trial of minocycline on translocator protein distribution volume in treatment-resistant major depressive disorder","year":2021,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Canada Research Chairs; University of Toronto; Centre for Addiction and Mental Health","funders":"CIHR Skin Research Training Centre; Centre for Addiction and Mental Health; Government of Canada; Canadian Institutes of Health Research; Government of Ontario; Azrieli Foundation","keywords":"Minocycline; Translocator protein; Gliosis; Placebo; Medicine; Major depressive disorder; Anterior cingulate cortex; Insula; Anesthesia; Internal medicine; Psychology; Pharmacology; Neuroscience; Pathology; Psychiatry; Neuroinflammation; Inflammation; Amygdala; Chemistry; Antibiotics","score_opus":0.026590528054985046,"score_gpt":0.28950987366748904,"score_spread":0.26291934561250396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3165869049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98767686,0.00046482394,0.00077213615,0.005851265,0.00039585,0.0033740834,0.00041117298,0.00004200112,0.001011795],"genre_scores_gemma":[0.9979727,0.000016388269,0.00025223996,0.00009475521,0.00013705756,0.0005996077,0.00021969492,0.000025489942,0.00068202516],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9977038,0.00023342515,0.0006911688,0.0005923864,0.00047251993,0.00030668982],"domain_scores_gemma":[0.9992169,0.0001980346,0.00017749231,0.00027548763,0.000045112873,0.00008698279],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011380211,0.00028041718,0.00046582997,0.00012887282,0.00011709754,0.000029862667,0.00016286116,0.00015337404,0.00029002895],"category_scores_gemma":[0.00006204298,0.0002462746,0.0003262946,0.00049515546,0.00011056834,0.00013380962,0.0000054111183,0.00017329925,0.000021170892],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.93882984,0.00461482,0.000702102,0.000060407932,0.00006243441,0.000012846797,0.00020998942,0.00058603205,0.040225066,0.013478917,0.00005394321,0.0011635966],"study_design_scores_gemma":[0.9636792,0.0007922701,0.0028122093,0.00008875866,0.00006333709,0.0000031290108,0.00006915524,0.0005816347,0.027571363,0.003361598,0.0006578328,0.00031949638],"about_ca_topic_score_codex":0.000048236758,"about_ca_topic_score_gemma":0.0008803322,"teacher_disagreement_score":0.024849372,"about_ca_system_score_codex":0.000039099927,"about_ca_system_score_gemma":0.00044994382,"threshold_uncertainty_score":0.9999989},"labels":[],"label_agreement":null},{"id":"W3167737554","doi":"10.1101/2021.06.14.448406","title":"Mouse models of immune dysfunction: Their neuroanatomical differences reflect their anxiety-behavioural phenotype","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; McMaster University; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Ontario Brain Institute","keywords":"Immune system; Neuroanatomy; Phenotype; Neuroscience; Biology; Endophenotype; Thalamus; Immune Dysfunction; Brain size; Psychology; Immunology; Magnetic resonance imaging; Gene; Genetics; Medicine","score_opus":0.03794778023770273,"score_gpt":0.22643622806600366,"score_spread":0.18848844782830093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3167737554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99479705,0.0011663381,0.0009064849,0.00018579121,0.001459077,0.0006290444,0.00032150742,0.0004968702,0.00003784002],"genre_scores_gemma":[0.99777985,0.0009921798,0.00044743795,0.00032345622,0.00016674996,0.00011195785,7.6198995e-7,0.0001643521,0.000013284776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995521,0.0005143607,0.00091593375,0.0017061939,0.0005855882,0.00075689144],"domain_scores_gemma":[0.99663615,0.00019349493,0.00065545924,0.0018888315,0.00035511842,0.00027095067],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032923813,0.000874647,0.0010548055,0.0002879308,0.0002431768,0.00032440032,0.0013361544,0.0006206264,0.00011907053],"category_scores_gemma":[0.0003466396,0.0007749261,0.000510965,0.0008621752,0.00044008903,0.00036022044,0.00097143126,0.001343518,0.000015224897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094952884,0.00037318814,0.0016856306,0.00018515257,0.000050445808,0.000022661272,0.00006573328,0.00013643822,0.9964739,0.00086262706,0.00003548124,0.000013775347],"study_design_scores_gemma":[0.0006326871,0.00008046525,0.03645696,0.00017516437,0.000044903463,7.573197e-8,0.000031272353,0.0028664167,0.95875806,0.000026126467,0.00011872287,0.0008091723],"about_ca_topic_score_codex":0.000083453466,"about_ca_topic_score_gemma":0.000006165037,"teacher_disagreement_score":0.037715882,"about_ca_system_score_codex":0.00014281902,"about_ca_system_score_gemma":0.0006117161,"threshold_uncertainty_score":0.9994702},"labels":[],"label_agreement":null},{"id":"W3169359632","doi":"10.2139/ssrn.3436249","title":"Inflammatory Cytokines Mediate Brain Dysconnectivity and Cognitive Deficits Across Major Psychiatric Disorders","year":2019,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Cognition; Psychiatry; Psychology; Neuroscience; Medicine","score_opus":0.005847718526843017,"score_gpt":0.24549567989688972,"score_spread":0.2396479613700467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3169359632","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99415976,0.0019385342,0.0005329365,0.0015557008,0.0004403006,0.00037872454,0.000016025362,0.000079378464,0.0008986665],"genre_scores_gemma":[0.9962023,0.0021648929,0.000007783798,0.0007378105,0.00015279543,0.000010410124,0.0000015734091,0.000045649216,0.00067678845],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9961193,0.00026266155,0.000302564,0.0005331778,0.0003673362,0.0024149164],"domain_scores_gemma":[0.9987899,0.0006219949,0.00023535747,0.00016578897,0.000041508825,0.00014547282],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010138227,0.00029086185,0.00026853362,0.00017036086,0.0004281629,0.00013522927,0.00030950378,0.00012378747,0.000057676967],"category_scores_gemma":[0.00072584656,0.0002583543,0.00012990316,0.00043247378,0.00018670998,0.00049262785,0.00009853521,0.00157831,0.00013688901],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002248962,0.0008870974,0.28219983,0.00025014783,0.0004142504,0.0000438724,0.004651063,0.00008503842,0.14686932,0.16820408,0.0004336263,0.3937127],"study_design_scores_gemma":[0.02364561,0.0033429852,0.20511295,0.0001747864,0.00013967634,0.0024200098,0.017064862,0.00063375745,0.018337365,0.72202015,0.004224103,0.002883757],"about_ca_topic_score_codex":0.000020984124,"about_ca_topic_score_gemma":0.0019015511,"teacher_disagreement_score":0.553816,"about_ca_system_score_codex":0.00014591015,"about_ca_system_score_gemma":0.00069117185,"threshold_uncertainty_score":0.9999869},"labels":[],"label_agreement":null},{"id":"W3169590529","doi":"10.1096/fasebj.2021.35.s1.02762","title":"Kynurenine Metabolism in the D2 <i>mdx</i> Mouse: A Muscle‐to‐Brain Connection","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Kynurenine; Kynurenine pathway; Kynurenic acid; Quinolinic acid; Neuroprotection; Dystrophin; mdx mouse; Metabolite; Duchenne muscular dystrophy; Chemistry; Biology; Internal medicine; Endocrinology; Neuroscience; Pharmacology; Biochemistry; Medicine; Glutamate receptor; Tryptophan","score_opus":0.024771009354228723,"score_gpt":0.2597151919287301,"score_spread":0.2349441825745014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3169590529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95987844,0.00028483573,0.0005601682,0.036105316,0.00053560216,0.00015752135,0.000009931936,0.000029952469,0.0024382083],"genre_scores_gemma":[0.97409683,0.00009578507,0.00006247613,0.024326902,0.00033657346,0.000010144484,0.0000010561017,0.000016016313,0.0010542026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99800116,0.00078554143,0.00024027983,0.00022017694,0.0004136021,0.0003392381],"domain_scores_gemma":[0.9989581,0.00051299616,0.00008995491,0.0003109746,0.000038390855,0.000089584326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082388514,0.00013439688,0.00014416956,0.00009485632,0.00039535423,0.00023670365,0.0005479303,0.000042958276,0.00031956818],"category_scores_gemma":[0.001218229,0.00007623425,0.00011096548,0.0007826081,0.00008500818,0.00015345076,0.000067672765,0.00059904857,0.00009618552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030444748,0.00008384504,0.000019250157,0.000002141939,0.000004246513,0.000113676375,0.002011714,0.00021565596,0.9797091,0.002766265,0.010907154,0.004136533],"study_design_scores_gemma":[0.0013908363,0.00006429796,0.0050159255,0.000022622888,0.0000140607235,0.0013434229,0.0029661034,0.00016254783,0.9260811,0.0035531886,0.059181876,0.00020401279],"about_ca_topic_score_codex":0.000013052503,"about_ca_topic_score_gemma":0.000089780864,"teacher_disagreement_score":0.053627968,"about_ca_system_score_codex":0.000023636769,"about_ca_system_score_gemma":0.00008750847,"threshold_uncertainty_score":0.34990475},"labels":[],"label_agreement":null},{"id":"W3170891571","doi":"10.1016/j.jad.2021.05.062","title":"Lower pro- to anti-inflammatory ratios associated with reduced neurocognitive flexibility in symptomatic adolescents with bipolar disorder","year":2021,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; Centre for Addiction and Mental Health; University of Toronto","funders":"H. Lundbeck A/S; Heart and Stroke Foundation of Canada; Pfizer; Brain and Behavior Research Foundation","keywords":"Neurocognitive; Bipolar disorder; Cognitive flexibility; Asymptomatic; Internal medicine; Medicine; Mood; Psychology; Bipolar I disorder; Clinical psychology; Psychiatry; Cognition; Mania","score_opus":0.010946044320912087,"score_gpt":0.25203237542240564,"score_spread":0.24108633110149355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3170891571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99715716,0.00013026396,0.0006586117,0.000512579,0.00018721727,0.001053833,0.000011119189,0.00004388296,0.00024533414],"genre_scores_gemma":[0.99901074,0.000034636258,0.00005567171,0.0007445246,0.000026815214,0.00003260185,0.000001937542,0.000058470792,0.000034612367],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9967699,0.0008322512,0.00052311877,0.0005920397,0.0007562331,0.00052643596],"domain_scores_gemma":[0.99822104,0.00038290018,0.00048658488,0.00027565233,0.00041533253,0.00021846504],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037861272,0.00037524808,0.0005550822,0.00037848222,0.00015488912,0.000098020086,0.00029362913,0.000102228165,0.000030898762],"category_scores_gemma":[0.0032947862,0.0002887251,0.00014703788,0.0017648031,0.00023118629,0.0005857018,0.00006911627,0.0006086974,0.000011468077],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028237435,0.006792821,0.7638694,0.0002882956,0.00022035858,0.0010219268,0.004962028,0.0045571537,0.20064683,0.000089027475,0.00015155844,0.014576859],"study_design_scores_gemma":[0.0066216155,0.00188371,0.93018913,0.0014414907,0.000056084198,0.00007709861,0.0019520052,0.00020543677,0.056638733,0.0002619386,0.00010101962,0.00057176204],"about_ca_topic_score_codex":0.000014472632,"about_ca_topic_score_gemma":0.0012452645,"teacher_disagreement_score":0.16631971,"about_ca_system_score_codex":0.0001851651,"about_ca_system_score_gemma":0.00051689893,"threshold_uncertainty_score":0.9999565},"labels":[],"label_agreement":null},{"id":"W3170949807","doi":"10.1016/j.cpnec.2021.100063","title":"Adolescent use of potential novel probiotic Rouxiella badensis subsp. acadiensis (Canan SV-53) mitigates pubertal LPS-Induced behavioral changes in adulthood in a sex-specific manner by modulating 5HT1A receptors expression in specific brain areas","year":2021,"lang":"en","type":"article","venue":"Comprehensive Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Anxiety; Lipopolysaccharide; Probiotic; Depression (economics); Endocrinology; Internal medicine; Microbiome; Receptor; Immune system; 5-HT receptor; Physiology; Psychology; Serotonin; Medicine; Biology; Immunology; Psychiatry; Bioinformatics","score_opus":0.06457230818674736,"score_gpt":0.2827928401925522,"score_spread":0.21822053200580482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3170949807","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99395967,0.00061442575,0.00003279934,0.00277246,0.0014618728,0.0009837982,0.000073885545,0.000069480484,0.000031614327],"genre_scores_gemma":[0.9972206,0.0008458955,0.00043541726,0.001098055,0.00006851937,0.00006962989,0.000052234718,0.00010259955,0.00010704535],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9940153,0.0010089325,0.0010868389,0.0020035442,0.00045413154,0.0014312735],"domain_scores_gemma":[0.9979814,0.00045435686,0.00036821447,0.0008136437,0.0001661117,0.00021627148],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000053872154,0.00066843245,0.0009819948,0.00096212345,0.00011170895,0.00008762585,0.0005361679,0.00024329254,0.000100046396],"category_scores_gemma":[0.00023010964,0.00074130966,0.0001943745,0.0015408795,0.00036854588,0.00024713523,0.00037343107,0.0010878546,0.000016630627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003463167,0.0017457725,0.018370958,0.00007558164,0.0000068782974,0.0010457506,0.0009613814,0.00027584183,0.97141665,0.00009197644,0.0014271985,0.004235674],"study_design_scores_gemma":[0.0057828436,0.00035034827,0.19293614,0.0005310892,0.00000885336,0.0005205668,0.0024670423,0.0004878597,0.7935698,0.00009272382,0.0024057063,0.0008470393],"about_ca_topic_score_codex":0.00018171043,"about_ca_topic_score_gemma":0.0012219141,"teacher_disagreement_score":0.17784688,"about_ca_system_score_codex":0.00015597114,"about_ca_system_score_gemma":0.000057974605,"threshold_uncertainty_score":0.9995038},"labels":[],"label_agreement":null},{"id":"W3173115656","doi":"10.1093/schizbullopen/sgab017","title":"Baseline Levels of C-Reactive Protein and Proinflammatory Cytokines Are Not Associated With Early Response to Amisulpride in Patients With First Episode Psychosis: The OPTiMiSE Cohort Study","year":2021,"lang":"en","type":"article","venue":"Schizophrenia Bulletin Open","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Cilag; École des Neurosciences Paris Île de France; Servier; Lundbeckfonden; Gedeon Richter; Ministerio de Economía y Competitividad; Agence Nationale de la Recherche; Allergan; Fondation FondaMental; Ministerio de Ciencia e Innovación; Fondation de France; Teva Pharmaceutical Industries; Sanofi; European Commission; H. Lundbeck A/S; Fundación Alicia Koplowitz; Instituto de Salud Carlos III; Amgen; Pfizer; Les Laboratories Pierre Fabre; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Amisulpride; Medicine; Proinflammatory cytokine; Confounding; Internal medicine; Schizophrenia (object-oriented programming); Psychosis; Logistic regression; Positive and Negative Syndrome Scale; Biomarker; Depression (economics); C-reactive protein; Antipsychotic; Inflammation; Psychiatry","score_opus":0.01657021331222588,"score_gpt":0.241597455817276,"score_spread":0.22502724250505013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173115656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98959696,0.0000092565815,0.000007909897,0.004451996,0.000024607678,0.0056312047,0.00014358976,0.000033893397,0.0001005891],"genre_scores_gemma":[0.99756306,0.0000012300354,0.00061502063,0.0004527272,0.000010671242,0.00083514384,0.000003842925,0.000050432976,0.0004678413],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99663323,0.0011063145,0.00042164797,0.0008627385,0.0006237599,0.00035228312],"domain_scores_gemma":[0.9979029,0.00074584037,0.00033991676,0.00063930824,0.00024279808,0.00012921706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011435838,0.0003145357,0.00047675864,0.00012039669,0.00023145358,0.00019789605,0.00066482305,0.00006624514,0.00010373336],"category_scores_gemma":[0.0035873568,0.00021052812,0.000032677905,0.00071866985,0.00017982864,0.00014479908,0.00039344613,0.00029675267,0.000016972304],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.063213624,0.0027147133,0.92331946,0.000036762864,0.00011327996,0.00015808363,0.0017255846,0.00021131136,0.00749768,0.000026583066,0.00052318326,0.00045976555],"study_design_scores_gemma":[0.008289425,0.0008725517,0.9663854,0.0005228599,0.00002313173,0.000002147417,0.00046262844,0.000007715907,0.022875767,0.000011079616,0.00023402572,0.00031322517],"about_ca_topic_score_codex":0.0002848948,"about_ca_topic_score_gemma":0.00351957,"teacher_disagreement_score":0.054924197,"about_ca_system_score_codex":0.000061367595,"about_ca_system_score_gemma":0.00013485593,"threshold_uncertainty_score":0.8585087},"labels":[],"label_agreement":null},{"id":"W3174111150","doi":"10.3390/ijms22136881","title":"Shared Biological Pathways between Antipsychotics and Omega-3 Fatty Acids: A Key Feature for Schizophrenia Preventive Treatment?","year":2021,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Cilag; Fondation Bettencourt Schueller; Agence Nationale de la Recherche","keywords":"Schizophrenia (object-oriented programming); Antipsychotic; Neuroprotection; Dopaminergic; Psychosis; Psychiatry; Medicine; Dopamine; Glutamatergic; Pharmacology; Bioinformatics; Psychology; Glutamate receptor; Internal medicine; Biology; Receptor","score_opus":0.10291090456917451,"score_gpt":0.3659625341864477,"score_spread":0.2630516296172732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174111150","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010425296,0.98558927,0.0017538755,0.00035043963,0.0008583006,0.00044613497,0.000450954,0.000014585078,0.000111162226],"genre_scores_gemma":[0.009057548,0.9847547,0.005637577,0.00014250683,0.0003045627,0.000016686583,0.00002908762,0.000019147727,0.000038221755],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99771374,0.00028800985,0.00054814573,0.0005491045,0.0006540221,0.00024695342],"domain_scores_gemma":[0.9981346,0.00060645374,0.00079846854,0.00012627685,0.00020358856,0.00013060638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003478149,0.00033081553,0.00089508266,0.000366699,0.00014224726,0.00042790407,0.0011606155,0.00020446848,0.00001340406],"category_scores_gemma":[0.00081154186,0.00021424012,0.00070292753,0.0003789434,0.00039534588,0.00023452449,0.00013644638,0.000262972,0.0000030238157],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084431405,0.000236284,0.00006798627,0.00020442477,0.00040218953,0.00045281163,0.00016605353,0.0000034559291,0.0018239423,0.003750147,0.0001865633,0.9926217],"study_design_scores_gemma":[0.003582812,0.002474028,0.0003561127,0.009791022,0.0005246604,0.0018063162,0.00022045663,0.000029768935,0.007354602,0.007875896,0.9649169,0.0010674476],"about_ca_topic_score_codex":5.598692e-7,"about_ca_topic_score_gemma":6.405774e-7,"teacher_disagreement_score":0.99155426,"about_ca_system_score_codex":0.00007994429,"about_ca_system_score_gemma":0.0004646623,"threshold_uncertainty_score":0.87364584},"labels":[],"label_agreement":null},{"id":"W3174848309","doi":"10.1101/2021.06.21.449337","title":"Fatty acid dysregulation in the anterior cingulate cortex of depressed suicides with a history of child abuse","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada First Research Excellence Fund","keywords":"Myelin; Anterior cingulate cortex; Choline; White matter; Phospholipid; Arachidonic acid; Polyunsaturated fatty acid; Chemistry; Internal medicine; Depression (economics); Endocrinology; Psychology; Fatty acid; Biochemistry; Medicine; Neuroscience; Central nervous system; Cognition; Magnetic resonance imaging","score_opus":0.01469644433351307,"score_gpt":0.20912017438332514,"score_spread":0.19442373004981206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174848309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99667054,0.0016035914,0.0004038537,0.00008598031,0.00036029142,0.00069852924,0.000052004292,0.000082599254,0.000042592408],"genre_scores_gemma":[0.9986513,0.00022137525,0.00058411923,0.00036154894,0.00004853251,0.000069879075,2.461967e-7,0.00006059167,0.0000023725272],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972431,0.00033985113,0.0006491421,0.00085672457,0.00055206456,0.00035913003],"domain_scores_gemma":[0.9975061,0.00013296807,0.00078371144,0.001297118,0.00020696931,0.00007315499],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038762385,0.00040928123,0.00063526916,0.0003136846,0.00005636627,0.000060381204,0.0007788235,0.00026314307,0.000035704565],"category_scores_gemma":[0.00031708443,0.00034011377,0.0001495558,0.0006162978,0.0004197161,0.00017818953,0.00017600786,0.0005351625,0.0000018263394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107387146,0.00025920087,0.007549138,0.0004670891,0.000026328049,0.00006276498,0.00028482708,0.00014920987,0.9909366,0.00013160345,0.000023180039,0.0000026884477],"study_design_scores_gemma":[0.00055062777,0.00004253411,0.4318547,0.000643932,0.000029005812,6.405299e-8,0.000015826747,0.00022724504,0.5662793,6.3384454e-7,0.00009998104,0.0002561769],"about_ca_topic_score_codex":0.00010723975,"about_ca_topic_score_gemma":0.00004228416,"teacher_disagreement_score":0.4246573,"about_ca_system_score_codex":0.00019702096,"about_ca_system_score_gemma":0.00051530875,"threshold_uncertainty_score":0.9999051},"labels":[],"label_agreement":null},{"id":"W3176183702","doi":"10.1096/fasebj.25.1_supplement.lb430","title":"Inflammatory alterations in dual diagnosis patients with schizophrenia and substance use disorders","year":2011,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Institut universitaire en santé mentale de Montréal; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research","keywords":"Schizophrenia (object-oriented programming); Medicine; Positive and Negative Syndrome Scale; Internal medicine; Psychopathology; Major depressive disorder; Psychiatry; Depression (economics); Substance abuse; Bipolar disorder; Dual diagnosis; Psychosis","score_opus":0.024596344087629722,"score_gpt":0.21144257910271033,"score_spread":0.1868462350150806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176183702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99892735,0.00003223062,0.000050294777,0.000097734555,0.000067930036,0.000148611,0.0000056703702,0.000017660364,0.00065250916],"genre_scores_gemma":[0.9993997,0.00011325781,0.00014366872,0.00019425665,0.000017854016,0.000011945778,3.5841472e-7,0.000017977167,0.00010093582],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992549,0.000116058945,0.00014011223,0.00013756563,0.0001627341,0.00018862363],"domain_scores_gemma":[0.9995779,0.00012419,0.000084142885,0.00012523656,0.000013688061,0.00007484947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008217992,0.000099825396,0.00007349779,0.00009122782,0.00021249668,0.0000837934,0.000109355955,0.000022026628,0.00013148296],"category_scores_gemma":[0.000107524094,0.00006243183,0.000019862,0.00016576986,0.00019099083,0.000394049,0.000020808786,0.00020827357,0.000014488931],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042455495,0.00027371247,0.98461396,0.0000042612137,0.00000928653,0.000041378942,0.0043475265,0.000031093365,0.004267101,0.0021947948,0.00025512266,0.0035371836],"study_design_scores_gemma":[0.0019935565,0.000106744854,0.9815076,0.00004178136,0.0000058474616,0.000024128083,0.0001449577,0.000032417465,0.01478331,0.0010625204,0.00014362746,0.00015348493],"about_ca_topic_score_codex":0.000018658598,"about_ca_topic_score_gemma":0.0009316568,"teacher_disagreement_score":0.010516209,"about_ca_system_score_codex":0.000012118453,"about_ca_system_score_gemma":0.000021776248,"threshold_uncertainty_score":0.2545896},"labels":[],"label_agreement":null},{"id":"W3176723170","doi":"10.1016/j.neulet.2021.136084","title":"Analysis of cognitive impairment in schizophrenia based on machine learning: Interaction between psychological stress and immune system","year":2021,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Department of Science and Technology of Sichuan Province","keywords":"Schizophrenia (object-oriented programming); Psychology; Cognition; Immune system; Clinical psychology; Glucocorticoid; Dysfunctional family; Internal medicine; Medicine; Psychiatry; Immunology","score_opus":0.027489458513096685,"score_gpt":0.29370459330139026,"score_spread":0.26621513478829356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176723170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979948,0.000010101163,0.00044627232,0.0010146446,0.00015684804,0.00014411498,0.000042174604,0.00004478416,0.00014628211],"genre_scores_gemma":[0.99772656,0.000006773129,0.000019287712,0.0022007665,0.000011173488,0.000009914671,0.000010018813,0.000007942097,0.0000075490634],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99792266,0.00045152925,0.00029535935,0.00070045027,0.0003731754,0.00025683935],"domain_scores_gemma":[0.9989725,0.0005963872,0.0001561864,0.00018642453,0.000017776281,0.00007072286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017037208,0.00015294725,0.0002968893,0.00049169787,0.00010840295,0.00006641167,0.0001905416,0.00004301643,0.000016790826],"category_scores_gemma":[0.00065702514,0.00013651157,0.00010342701,0.0019354975,0.00026736307,0.00013232068,0.000066190594,0.00033596499,0.0000026091127],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003224927,0.0004626173,0.21021439,0.00004724891,0.000009748206,0.00022844844,0.0002266658,0.009661367,0.7763616,0.00009070928,0.0000036817212,0.0023710092],"study_design_scores_gemma":[0.0011505955,0.00030114772,0.7794844,0.0001308758,0.000044811142,0.0000062417485,0.0002085192,0.037730567,0.18078128,0.0000018010696,0.000006476229,0.0001532865],"about_ca_topic_score_codex":0.000021380318,"about_ca_topic_score_gemma":0.000008627328,"teacher_disagreement_score":0.59558034,"about_ca_system_score_codex":0.00003608672,"about_ca_system_score_gemma":0.000013944486,"threshold_uncertainty_score":0.55667806},"labels":[],"label_agreement":null},{"id":"W3177304028","doi":"10.1096/fasebj.2019.33.1_supplement.lb568","title":"The absence of AMPK beta1 exacerbates the acute olanzapine‐induced hyperglycemia in female mice","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Olanzapine; AMPK; Internal medicine; Endocrinology; AMP-activated protein kinase; Antipsychotic; Medicine; Protein kinase A; Glucagon; Chemistry; Insulin; Phosphorylation; Schizophrenia (object-oriented programming); Biochemistry","score_opus":0.02352829295414502,"score_gpt":0.25816321007106174,"score_spread":0.23463491711691672,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177304028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940691,0.0002893155,0.000009439331,0.0028728885,0.00048439982,0.00023344943,0.0000054439697,0.000013201543,0.0020227437],"genre_scores_gemma":[0.9973752,0.00044082926,0.000014630612,0.0009152346,0.000085384105,0.000004367716,2.3738124e-7,0.00001506643,0.0011490672],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841934,0.00031623413,0.00031383845,0.00018296928,0.00039318,0.0003744303],"domain_scores_gemma":[0.99824584,0.0009902652,0.00024752476,0.000426027,0.00003560502,0.000054731165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006999561,0.00014567068,0.00016261227,0.000048928807,0.000404943,0.00012749959,0.0012245156,0.000047195368,0.000110013454],"category_scores_gemma":[0.00026547763,0.00006322985,0.00011339417,0.00037209466,0.00025053197,0.00015539367,0.00012016556,0.0006118342,0.00013954272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001274364,0.000028261244,0.0020943454,0.000004113679,0.00001262454,0.000011390198,0.001114394,0.0000918559,0.99419576,0.0006613045,0.000296189,0.0013623108],"study_design_scores_gemma":[0.0013415792,0.00017320759,0.025251038,0.000068626316,0.000014542719,0.00039342043,0.002904783,0.0006293286,0.9659237,0.0016370071,0.001467517,0.00019521573],"about_ca_topic_score_codex":0.000031063966,"about_ca_topic_score_gemma":0.000033969587,"teacher_disagreement_score":0.02827204,"about_ca_system_score_codex":0.000028009457,"about_ca_system_score_gemma":0.00008885197,"threshold_uncertainty_score":0.31145352},"labels":[],"label_agreement":null},{"id":"W3177494555","doi":"10.1016/j.psyneuen.2021.105348","title":"Hypothalamus volume and DNA methylation of stress axis genes in major depressive disorder: A CAN-BIND study report","year":2021,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"St. Michael's Hospital; University of Toronto; Centre for Addiction and Mental Health; McGill University; Simon Fraser University; Baycrest Hospital; Dalhousie University; Hamilton Health Sciences; Douglas Mental Health University Institute; Juravinski Hospital; McMaster University; Queen's University; University of Calgary; University of British Columbia; St. Joseph’s Healthcare Hamilton","funders":"Canadian Institutes of Health Research; H. Lundbeck A/S; Government of Ontario; Ontario Ministry of Research, Innovation and Science; Ontario Brain Institute; Ontario Ministry of Research and Innovation; Servier; Pfizer; Bristol-Myers Squibb","keywords":"FKBP5; Major depressive disorder; DNA methylation; Glucocorticoid receptor; Methylation; CpG site; Internal medicine; Antidepressant; Biomarker; Oncology; Gene; Depression (economics); Medicine; Psychology; Endocrinology; Glucocorticoid; Gene expression; Biology; Genetics; Hippocampus","score_opus":0.024187612946307287,"score_gpt":0.2853118175628568,"score_spread":0.2611242046165495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177494555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961432,0.00091893726,0.000042945914,0.0012803451,0.0005074856,0.00047894678,0.00003608334,0.000048841397,0.0005431962],"genre_scores_gemma":[0.99874514,0.00038791128,0.00006144864,0.00018501206,0.000025875986,0.00007358288,0.000006606604,0.000028290813,0.00048611758],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99736077,0.0005098106,0.00052311394,0.0009354107,0.00023329147,0.0004376264],"domain_scores_gemma":[0.9988121,0.00026184507,0.00023198163,0.000560572,0.00006032428,0.000073177966],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000043867545,0.00022071469,0.00038757676,0.00025114187,0.00008778172,0.000025596475,0.00022617774,0.000046417175,0.00007676443],"category_scores_gemma":[0.0007178995,0.00022982582,0.000059971164,0.00052613317,0.00021757526,0.00010223534,0.00016908495,0.00022665756,0.000006385914],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012309477,0.0014371049,0.6947078,0.000052889725,0.000027318236,0.0061511085,0.00089237146,0.000054306187,0.28175586,0.0002033522,0.00007668357,0.014518104],"study_design_scores_gemma":[0.0035384428,0.0003076122,0.70066094,0.0000135729,0.000023914217,0.001476066,0.0013570988,0.000078386576,0.29040834,0.0007873813,0.0010750233,0.00027324128],"about_ca_topic_score_codex":0.00023808534,"about_ca_topic_score_gemma":0.0017902092,"teacher_disagreement_score":0.014244862,"about_ca_system_score_codex":0.000013597869,"about_ca_system_score_gemma":0.000055723118,"threshold_uncertainty_score":0.9372025},"labels":[],"label_agreement":null},{"id":"W3179114264","doi":"10.3889/oamjms.2021.6305","title":"Correlation between C-reactive Protein Levels with Cognitive Function and Body Mass Index in Schizophrenia","year":2021,"lang":"en","type":"article","venue":"Open Access Macedonian Journal of Medical Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Body mass index; Schizophrenia (object-oriented programming); Inclusion and exclusion criteria; Cognition; Correlation; Pearson product-moment correlation coefficient; Internal medicine; Correlation coefficient; Cross-sectional study; Psychiatry; Statistics; Pathology","score_opus":0.08002051764355939,"score_gpt":0.37130461942268084,"score_spread":0.29128410177912145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179114264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98697966,0.000077454795,0.0049107214,0.005651935,0.00013025003,0.00030164106,0.0000053748854,0.000005925742,0.001937044],"genre_scores_gemma":[0.99929565,0.0000145438125,0.00018693003,0.00034520932,0.000077590536,0.000007773781,5.565259e-7,0.0000068187164,0.00006494873],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971921,0.00037867168,0.00037729493,0.0003775003,0.0014135054,0.00026096127],"domain_scores_gemma":[0.9986971,0.00047036476,0.00039600625,0.00006691647,0.000090822774,0.0002787814],"candidate_categories":["scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.0014440621,0.00013320522,0.00027702362,0.00020355025,0.00023626955,0.0010373744,0.0009619646,0.000099128316,0.0004442062],"category_scores_gemma":[0.0018812233,0.00009149163,0.000028242252,0.0012290213,0.00067206327,0.0027956325,0.0003426303,0.0005421598,0.000004428864],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015799121,0.00040636107,0.8314583,0.00005238413,0.00005583474,0.0012564556,0.00052286714,0.000117889176,0.018610476,0.0054520154,0.000086405744,0.14040112],"study_design_scores_gemma":[0.0051243785,0.00061774696,0.9550279,0.0009951309,0.00002292968,0.00021848876,0.0011267215,0.0008632264,0.025126712,0.010493552,0.00013710403,0.00024612504],"about_ca_topic_score_codex":0.00005724515,"about_ca_topic_score_gemma":0.00014996868,"teacher_disagreement_score":0.140155,"about_ca_system_score_codex":0.000030883097,"about_ca_system_score_gemma":0.0010000004,"threshold_uncertainty_score":0.99999964},"labels":[],"label_agreement":null},{"id":"W3179198471","doi":"10.1097/yco.0000000000000727","title":"Recent trends in the management of depression in persons with cancer","year":2021,"lang":"en","type":"review","venue":"Current Opinion in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Psychological intervention; Depression (economics); Medicine; Comorbidity; Management of depression; Cancer; Psychotherapist; Psychiatry; Clinical psychology; Intensive care medicine; Alternative medicine; Psychology; Internal medicine","score_opus":0.1197596379590261,"score_gpt":0.41943655068701624,"score_spread":0.29967691272799013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179198471","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008764406,0.9911235,0.0000029905839,0.00029770719,0.0069017606,0.00053956924,0.000044725624,0.0000101577825,0.0009919578],"genre_scores_gemma":[0.000069438946,0.9992425,0.000047351466,0.000034365978,0.00010210958,0.00039700296,0.000052610536,0.000024822615,0.000029828441],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99768317,0.0004198801,0.000566741,0.00065275986,0.00037427832,0.00030314975],"domain_scores_gemma":[0.9991658,0.00006712872,0.00026730567,0.00045911712,0.000007669181,0.000033031138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019648198,0.00030805948,0.0006549981,0.00055530656,0.00003168323,0.000024710796,0.0005736389,0.000111434056,0.00014327139],"category_scores_gemma":[0.00000822481,0.00019606332,0.00016204591,0.0025342116,0.00006255731,0.00005752344,0.00009731848,0.0006121574,0.0000031321244],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010932909,0.0005497309,0.0009777042,0.009243641,0.00000721644,0.000002435466,0.00023421091,0.000009489086,5.7080225e-8,0.00069392595,0.004395767,0.9838749],"study_design_scores_gemma":[0.00073366956,0.000022432952,0.0021765784,0.066824645,0.00002342241,0.0000061089704,0.0003922548,0.000005775885,3.9451393e-7,0.000029091365,0.92954177,0.00024386034],"about_ca_topic_score_codex":0.000015134605,"about_ca_topic_score_gemma":0.0001094399,"teacher_disagreement_score":0.983631,"about_ca_system_score_codex":0.00010271465,"about_ca_system_score_gemma":0.00017024559,"threshold_uncertainty_score":0.79952306},"labels":[],"label_agreement":null},{"id":"W3179742741","doi":"10.1038/s41398-021-01505-5","title":"Clinical laboratory tests and five-year incidence of major depressive disorder: a prospective cohort study of 433,890 participants from the UK Biobank","year":2021,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Centre for Addiction and Mental Health","funders":"Natural Sciences and Engineering Research Council of Canada; Krembil Foundation; University of Toronto; Canadian Institutes of Health Research; Medical Research Council; Kavli Foundation","keywords":"Medicine; Major depressive disorder; Prospective cohort study; Internal medicine; Odds ratio; Cohort; Confidence interval","score_opus":0.02598921961036125,"score_gpt":0.32443518715252967,"score_spread":0.2984459675421684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179742741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99678874,0.0010543561,0.00006661152,0.00071980676,0.00026990494,0.0005986879,0.0003127127,0.00001861271,0.00017057256],"genre_scores_gemma":[0.9990955,0.00006437647,0.0004298876,0.00027457185,0.00006862007,0.000032293334,0.0000070234328,0.000013092156,0.000014635036],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99803954,0.00033789658,0.00051182276,0.00050288317,0.00043530262,0.0001725333],"domain_scores_gemma":[0.9983182,0.0009670955,0.00020123283,0.0003206654,0.00012654313,0.00006628976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022067333,0.00014053432,0.00027712484,0.000029724017,0.00012495634,0.000018030356,0.00022056609,0.00007310996,0.00013064774],"category_scores_gemma":[0.00042988468,0.00011026616,0.00007377543,0.00041203634,0.00035377734,0.00010869512,0.000042280295,0.00020360957,0.000005923181],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016002446,0.00095221517,0.9935461,0.000014036973,0.000059100174,0.0000028807362,0.0010715827,0.0000447153,0.0024632902,0.0013967612,0.000121458164,0.00016780267],"study_design_scores_gemma":[0.0024510378,0.00016587443,0.9887569,0.000040720824,0.00006515772,9.997775e-7,0.0010666952,0.00007833469,0.001214951,0.00603026,0.000011920251,0.000117147],"about_ca_topic_score_codex":0.00012483934,"about_ca_topic_score_gemma":0.0019190434,"teacher_disagreement_score":0.004789231,"about_ca_system_score_codex":0.0000040538002,"about_ca_system_score_gemma":0.0002834836,"threshold_uncertainty_score":0.44965234},"labels":[],"label_agreement":null},{"id":"W3179926303","doi":"10.1038/s41380-021-01197-9","title":"Dysregulation of complement and coagulation pathways: emerging mechanisms in the development of psychosis","year":2021,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; University of Bristol; Health Research Board; Health Service Executive; Wellcome Trust; Canadian Institute for Theoretical Astrophysics","keywords":"Psychosis; Neuroscience; Psychology; Complement (music); Coagulation; Complement system; Schizophrenia (object-oriented programming); Medicine; Psychiatry; Immunology; Biology; Genetics; Phenotype","score_opus":0.06285934230301699,"score_gpt":0.32655449034055556,"score_spread":0.2636951480375386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179926303","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003797043,0.98452914,0.009960586,0.00010393705,0.00034474224,0.0009333429,0.000019793806,0.00001314874,0.0002982809],"genre_scores_gemma":[0.04925378,0.92046666,0.029363286,0.00039241003,0.000035746365,0.00022540386,0.00016536898,0.000088782275,0.000008545048],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978113,0.00039177036,0.00081781397,0.0004013783,0.00040906254,0.00016864223],"domain_scores_gemma":[0.9990571,0.000075168646,0.00047551442,0.00034538162,0.000022221633,0.000024587398],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035077287,0.00023685671,0.00062613137,0.00021965914,0.000062546955,0.000019402863,0.0002756289,0.00009440684,0.000022645017],"category_scores_gemma":[0.00003783061,0.00018693195,0.0001776897,0.0006075048,0.000045899997,0.000033603377,0.00006913027,0.00014065059,0.0000012341918],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000616044,0.0003957761,0.0000335122,0.0088173235,0.000056473145,0.000004452964,0.0013718185,0.000019713052,0.003958662,0.08580122,0.000088825174,0.89944607],"study_design_scores_gemma":[0.00708456,0.0007631483,0.004751643,0.09407294,0.0015313736,0.00020493568,0.009681065,0.0007272583,0.05271619,0.06551996,0.7576714,0.005275528],"about_ca_topic_score_codex":0.0000033254566,"about_ca_topic_score_gemma":0.0000324246,"teacher_disagreement_score":0.8941705,"about_ca_system_score_codex":0.00002198369,"about_ca_system_score_gemma":0.00016563876,"threshold_uncertainty_score":0.76228637},"labels":[],"label_agreement":null},{"id":"W3180138345","doi":"10.1038/s41380-021-01205-y","title":"Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity","year":2021,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Aging; National Institute of Mental Health; U.S. Department of Health and Human Services","keywords":"Biology; Neuroscience; Schizophrenia (object-oriented programming); Gene expression; Microarray; Gene; Genetics; Psychology; Psychiatry","score_opus":0.015386044376401726,"score_gpt":0.23839056822578453,"score_spread":0.2230045238493828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3180138345","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99466544,0.0014727949,0.000663278,0.000584813,0.00080239563,0.00022348335,0.0000678331,0.000033981556,0.0014859885],"genre_scores_gemma":[0.9986865,0.00007334501,0.00068801426,0.00033161562,0.0000486525,0.000017309778,0.000025709207,0.00002989671,0.00009899306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980983,0.00028716444,0.00047566576,0.000457101,0.00039989944,0.00028184106],"domain_scores_gemma":[0.9992265,0.00005417512,0.00015194349,0.00045402758,0.000055751672,0.00005756897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001255212,0.0001856939,0.00026271158,0.00017780667,0.000064183245,0.000016212063,0.0002771419,0.00008724517,0.0004718985],"category_scores_gemma":[0.000089206216,0.00020853846,0.0001996277,0.0007875652,0.00024409742,0.00010666585,0.00005507956,0.00036228698,0.00001587232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017233082,0.00044194292,0.0006789209,0.00012904534,0.000006186393,0.000020619218,0.00004353674,0.00029763495,0.9729048,0.02417223,0.00024074898,0.0008919793],"study_design_scores_gemma":[0.0025949187,0.00027159989,0.21734689,0.000094399446,0.00001149484,0.000043856522,0.000078515404,0.00022085094,0.77428734,0.0041929516,0.00060530717,0.00025184537],"about_ca_topic_score_codex":0.000011714559,"about_ca_topic_score_gemma":0.000032764867,"teacher_disagreement_score":0.21666797,"about_ca_system_score_codex":0.000041731037,"about_ca_system_score_gemma":0.0003994598,"threshold_uncertainty_score":0.85039514},"labels":[],"label_agreement":null},{"id":"W3182833340","doi":"10.1093/braincomms/fcab139","title":"Serum metabolites associated with brain amyloid beta deposition, cognition and dementia progression","year":2021,"lang":"en","type":"article","venue":"Brain Communications","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; U.S. National Library of Medicine; National Institute of Neurological Disorders and Stroke; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; University of California, San Diego; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; National Institute on Aging; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Dementia; Alzheimer's disease; Neuroimaging; Amyloid (mycology); Cognitive decline; Internal medicine; Medicine; Psychology; Metabolite; Disease; Endocrinology; Pathology; Neuroscience","score_opus":0.03270832274710121,"score_gpt":0.2948260422334531,"score_spread":0.2621177194863519,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3182833340","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8518246,0.006616038,0.0016118616,0.12075973,0.00009357466,0.001084471,0.0003066265,0.0006003093,0.017102817],"genre_scores_gemma":[0.99132097,0.0003050849,0.0026181517,0.0050582117,0.000012161751,0.00009068483,0.00025826646,0.000024413706,0.0003120722],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982943,0.00069788774,0.00021897937,0.00032787136,0.00022468576,0.00023626762],"domain_scores_gemma":[0.99750084,0.0013417446,0.00013647185,0.0007981535,0.00013140256,0.00009139605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021742188,0.00014588611,0.00015124574,0.000075965036,0.00073513354,0.00017002501,0.00037549535,0.000071107155,0.00007332883],"category_scores_gemma":[0.0012533091,0.00013619196,0.00004242581,0.00062187004,0.0003409165,0.00027545905,0.0003051844,0.00020181539,0.0000144947335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026744176,0.0010255446,0.0041734623,0.000031329793,0.0001274524,0.000015326055,0.0009336508,0.000004986283,0.9383733,0.026928088,0.0044452013,0.0239149],"study_design_scores_gemma":[0.0036898672,0.00019400041,0.13909371,0.00044870249,0.00021423321,0.000110119094,0.0010367462,0.0015208981,0.81836396,0.007453753,0.02707489,0.0007991263],"about_ca_topic_score_codex":0.0000052656346,"about_ca_topic_score_gemma":0.00029333244,"teacher_disagreement_score":0.13949639,"about_ca_system_score_codex":0.000016121077,"about_ca_system_score_gemma":0.00008514354,"threshold_uncertainty_score":0.5654127},"labels":[],"label_agreement":null},{"id":"W3183369022","doi":"10.1016/b978-0-323-85666-9.00017-6","title":"Mitochondrial dysfunction and affective disorders: Focus on diet, exercise, and aging","year":2021,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Mitochondrion; Oxidative stress; Mood disorders; Neuroscience; Apoptosis; Bipolar disorder; Reactive oxygen species; Neuroplasticity; Biology; Inflammation; Psychology; Bioinformatics; Cognition; Cell biology; Endocrinology; Psychiatry; Genetics; Anxiety; Immunology","score_opus":0.012907849828346805,"score_gpt":0.22853512398958903,"score_spread":0.21562727416124222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183369022","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010987561,0.0026764479,0.000011983785,0.00019343027,0.0010025474,0.0009250835,0.0000332506,0.000115517185,0.993943],"genre_scores_gemma":[0.023139937,0.002859045,0.000072534734,0.00057534,0.00046748278,0.00008417669,0.0000093261515,0.00014503933,0.97264713],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99793327,0.00006606607,0.00024654443,0.001087315,0.00034133348,0.0003254947],"domain_scores_gemma":[0.99899423,0.00029972708,0.00016012657,0.00037314667,0.000026073885,0.00014666867],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006476903,0.00050962257,0.0004939031,0.00019139212,0.00026852416,0.0001631764,0.00013668138,0.0002903503,0.00008503161],"category_scores_gemma":[0.00010473248,0.0004860268,0.00015297905,0.000026844185,0.00033110104,0.0000880594,0.00019242067,0.00054363586,0.00003564549],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015408965,0.000017391952,0.0000025148431,0.000096703676,0.000017950768,0.000031385294,0.0002890138,3.144513e-7,0.0020198931,0.0067364178,0.000084549,0.9905498],"study_design_scores_gemma":[0.0040228283,0.0011777923,0.00025115066,0.0039024875,0.00024752208,0.000056574398,0.0001652312,0.000027955606,0.012486006,0.12730715,0.84822154,0.0021337916],"about_ca_topic_score_codex":0.0000018145574,"about_ca_topic_score_gemma":0.00010010723,"teacher_disagreement_score":0.98841596,"about_ca_system_score_codex":0.000045625904,"about_ca_system_score_gemma":0.000047786478,"threshold_uncertainty_score":0.99975914},"labels":[],"label_agreement":null},{"id":"W3183725450","doi":"10.3390/brainsci11070941","title":"Glutathione as a Molecular Marker of Functional Impairment in Patients with At-Risk Mental State: 7-Tesla 1H-MRS Study","year":2021,"lang":"en","type":"article","venue":"Brain Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St Joseph's Health Care; Lawson Health Research Institute; Western University","funders":"","keywords":"At risk mental state; Glutathione; Schizophrenia (object-oriented programming); Medicine; Psychosis; Internal medicine; Anterior cingulate cortex; Clinical psychology; Psychiatry; Psychology; Cognition; Biology","score_opus":0.010948093290788555,"score_gpt":0.24571531732976462,"score_spread":0.23476722403897607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183725450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99779236,0.000030915377,0.00003387591,0.0005043598,0.00013908518,0.0004848744,0.00003257605,0.000020972135,0.00096099306],"genre_scores_gemma":[0.99870473,0.0000055918226,0.00012855236,0.000724331,0.00000449284,0.000022186003,0.0000040647446,0.000009064997,0.0003969784],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99726206,0.00034767992,0.0002686391,0.0006417938,0.0011485546,0.00033128864],"domain_scores_gemma":[0.99927783,0.00024533746,0.00014605446,0.00019665319,0.000050334274,0.000083774554],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000523271,0.00015452085,0.00017076978,0.00015118423,0.00023007805,0.000056661625,0.0002522446,0.000025034018,0.00040880693],"category_scores_gemma":[0.00048460666,0.000119791584,0.000049078317,0.001188046,0.00048691072,0.00021345881,0.00019393349,0.000102444086,0.000025772044],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00062136556,0.0041214917,0.9309149,0.000016033762,0.000022285829,0.0001227736,0.0048808684,0.0012172693,0.054566648,0.0003459933,0.00071756804,0.002452803],"study_design_scores_gemma":[0.0032952647,0.0014426484,0.9639181,0.000021504276,0.000004823102,0.000007648732,0.0027103166,0.00020907169,0.027466414,0.0005048452,0.00019984611,0.00021952085],"about_ca_topic_score_codex":0.000076317054,"about_ca_topic_score_gemma":0.00014291186,"teacher_disagreement_score":0.033003196,"about_ca_system_score_codex":0.000063612766,"about_ca_system_score_gemma":0.00022245776,"threshold_uncertainty_score":0.4884959},"labels":[],"label_agreement":null},{"id":"W3185101209","doi":"10.1111/acps.13351","title":"Increased C‐reactive protein concentration and suicidal behavior in people with psychiatric disorders: A systematic review and meta‐analysis","year":2021,"lang":"en","type":"review","venue":"Acta Psychiatrica Scandinavica","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Ottawa Hospital; University of Ottawa; Dalhousie University","funders":"","keywords":"Suicidal ideation; Meta-analysis; Observational study; Suicide attempt; Internal medicine; Mood disorders; PsycINFO; Psychiatry; Medicine; Strictly standardized mean difference; Mood; Publication bias; Poison control; Psychology; Clinical psychology; Injury prevention; MEDLINE; Anxiety","score_opus":0.02675409133318111,"score_gpt":0.30765181361439137,"score_spread":0.28089772228121024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185101209","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00045966613,0.98926383,0.000013300216,0.0004612431,0.000037995924,0.009320937,0.00016289168,0.00006678447,0.00021337054],"genre_scores_gemma":[0.01461243,0.98047537,0.00019555948,0.0003323621,0.000021927015,0.0040953974,0.00009454098,0.00008003624,0.000092368835],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9944921,0.001479271,0.0012427405,0.001628019,0.0005625411,0.00059531524],"domain_scores_gemma":[0.99704003,0.000604683,0.0011811634,0.0008423153,0.000051607876,0.00028017163],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003919364,0.0009404731,0.0064496743,0.0006168553,0.00022429957,0.00023655184,0.00045818696,0.00030121018,0.000119194105],"category_scores_gemma":[0.00028688458,0.000651135,0.0010280085,0.0062703337,0.00016682083,0.00030710164,0.00011626997,0.00064678566,0.0000056521267],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005666475,0.001432983,0.00065665983,0.97839856,0.016864477,0.000049307797,0.00020928933,1.7370549e-7,0.000006580334,0.00059181993,0.00018356237,0.0015499204],"study_design_scores_gemma":[0.0012666029,0.00045307315,0.00039049477,0.016256096,0.97541505,0.00022961339,0.00013701296,0.000007862857,0.000002350957,0.000048480735,0.004040801,0.0017525315],"about_ca_topic_score_codex":0.00041442167,"about_ca_topic_score_gemma":0.0012624606,"teacher_disagreement_score":0.96214247,"about_ca_system_score_codex":0.00010567388,"about_ca_system_score_gemma":0.00037121738,"threshold_uncertainty_score":0.999594},"labels":[],"label_agreement":null},{"id":"W3185469896","doi":"10.1096/fasebj.30.1_supplement.293.7","title":"Ldlr <sup>−/−</sup> Mice Lacking PEMT Have Elevated Plasma Trimethylamine‐oxide Levels But Are Protected From High Fat Diet‐Induced Atherosclerosis.","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Alberta Livestock and Meat Agency","keywords":"LDL receptor; Choline; Internal medicine; Endocrinology; Trimethylamine; Cholesterol; Apolipoprotein E; Phosphatidylcholine; Chemistry; Biology; Lipoprotein; Phospholipid; Biochemistry; Medicine","score_opus":0.056944013046410225,"score_gpt":0.2525012187777011,"score_spread":0.19555720573129087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185469896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99498844,0.00004350019,0.00083097775,0.0025196574,0.0003529178,0.00060993177,0.00029501735,0.00020955823,0.00014999215],"genre_scores_gemma":[0.99631304,0.00005429245,0.00031089433,0.00090614357,0.00048771084,0.000031025673,0.0000031640766,0.00009800932,0.0017957148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99583966,0.0009837209,0.0006935164,0.00069177645,0.00083476305,0.0009565621],"domain_scores_gemma":[0.99687135,0.0013741684,0.00067691394,0.00062263024,0.00014946514,0.00030548134],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053998304,0.0005129498,0.0005026069,0.0001946517,0.00088100065,0.0003409755,0.0012696852,0.00023260701,0.0007013493],"category_scores_gemma":[0.0020685748,0.0002953096,0.00027419443,0.000447726,0.000296272,0.00049272133,0.00020849501,0.00093944935,0.00042460437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042729906,0.00011571195,0.0005848636,0.0000063470998,0.000048807822,0.000046796515,0.00067230145,0.00007441988,0.9946188,0.00004198735,0.0005062411,0.0028564595],"study_design_scores_gemma":[0.0040125367,0.00023142538,0.019793112,0.0002595588,0.00003481685,0.00007627615,0.0008711037,0.00048392694,0.9724821,0.001089209,0.00019533282,0.00047059238],"about_ca_topic_score_codex":0.00017371685,"about_ca_topic_score_gemma":0.00003482678,"teacher_disagreement_score":0.022136655,"about_ca_system_score_codex":0.00018223135,"about_ca_system_score_gemma":0.00012775397,"threshold_uncertainty_score":0.99994993},"labels":[],"label_agreement":null},{"id":"W3185845415","doi":"10.1038/s41380-021-01222-x","title":"Diversity of mechanism of action of psychotropic drugs in their anti-COVID-19 properties","year":2021,"lang":"en","type":"letter","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Coronavirus disease 2019 (COVID-19); Mechanism (biology); Diversity (politics); Mechanism of action; Action (physics); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Neuroscience; Pharmacology; Medicine; Psychology; Virology; Chemistry; Sociology; Epistemology; Philosophy","score_opus":0.03972142769199355,"score_gpt":0.2575895304094485,"score_spread":0.21786810271745494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185845415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92565197,0.00072875305,0.00076777564,0.070516035,0.0013703444,0.00044458106,0.000076106786,0.0000328754,0.00041157758],"genre_scores_gemma":[0.89554346,0.00016557884,0.00017366704,0.10388284,0.00008438795,0.000008083868,0.000015226022,0.00003626815,0.000090469635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977441,0.00037750747,0.00047701667,0.000588636,0.00053729396,0.0002754617],"domain_scores_gemma":[0.9987339,0.000044150518,0.00048530163,0.0006394514,0.000050234677,0.000047012985],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010938974,0.0002892255,0.00057455857,0.00038749934,0.00009312587,0.000008260964,0.00062095444,0.0003918365,0.00006882264],"category_scores_gemma":[0.00011363619,0.00026706496,0.0003415737,0.0005472045,0.00022279314,0.00006756441,0.00033892988,0.00065448374,0.0000019782221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000101148915,0.00052047294,0.0015185779,0.003853598,0.00007482774,0.00006756486,0.0021635408,0.00005387451,0.96069777,0.0018793433,0.028886765,0.0001825248],"study_design_scores_gemma":[0.0014919585,0.00016764188,0.0006782783,0.00041844093,0.000044755343,0.000015175886,0.0008190408,0.000027484532,0.9824989,0.008752527,0.004642705,0.00044311935],"about_ca_topic_score_codex":0.00021176998,"about_ca_topic_score_gemma":0.000032099146,"teacher_disagreement_score":0.033366807,"about_ca_system_score_codex":0.00004160074,"about_ca_system_score_gemma":0.00033213114,"threshold_uncertainty_score":0.9999782},"labels":[],"label_agreement":null},{"id":"W3186279334","doi":"10.1001/jamapsychiatry.2021.1818","title":"Association Between Mood Disorders and Risk of COVID-19 Infection, Hospitalization, and Death","year":2021,"lang":"en","type":"review","venue":"JAMA Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":208,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Medicine; PsycINFO; Mood disorders; Mood; Cochrane Library; Odds ratio; MEDLINE; Meta-analysis; Psychiatry; Comorbidity; Internal medicine; Anxiety","score_opus":0.02403390865764401,"score_gpt":0.3135828011669223,"score_spread":0.2895488925092783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186279334","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0032063688,0.9929899,0.0004951741,0.000895603,0.0006740054,0.00062795304,0.00034673614,0.000087435576,0.0006768235],"genre_scores_gemma":[0.00074134656,0.99840015,0.00013144809,0.00019562145,0.00020207107,0.000034200242,0.000082400395,0.00004579161,0.00016694491],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976416,0.0006016918,0.0005641816,0.00065342366,0.00030182084,0.00023726176],"domain_scores_gemma":[0.9978822,0.0006591656,0.0009493509,0.00028913782,0.000044074466,0.00017610537],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003449613,0.0003324002,0.00089875463,0.00022232824,0.00024033144,0.00012827503,0.00014862543,0.00048152255,0.000039416685],"category_scores_gemma":[0.0029602302,0.00031057853,0.00023266494,0.00069463725,0.00007234337,0.0001842513,0.00010146292,0.00037663424,0.0000049571527],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000033838085,0.00013679391,0.71346146,0.00995684,0.00029113033,3.6000168e-7,0.00019049484,0.000002522676,2.5831147e-7,0.0028364602,0.007084252,0.26603603],"study_design_scores_gemma":[0.0008978808,0.00008383287,0.030139506,0.0011518535,0.0009210569,0.000007112782,0.000042291897,0.000003975332,0.0000016371247,0.004458686,0.96184903,0.00044311883],"about_ca_topic_score_codex":0.00016291744,"about_ca_topic_score_gemma":0.00028854096,"teacher_disagreement_score":0.9547648,"about_ca_system_score_codex":0.00009181492,"about_ca_system_score_gemma":0.00042309368,"threshold_uncertainty_score":0.9999346},"labels":[],"label_agreement":null},{"id":"W3186505697","doi":"10.1016/j.bbih.2021.100303","title":"Transdiagnostic biomarker approaches to mental health disorders: Consideration of symptom complexity, comorbidity and context","year":2021,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Royal Ottawa Mental Health Centre; University of Ottawa","funders":"National Institute on Minority Health and Health Disparities; Canadian Institutes of Health Research; University of Ottawa","keywords":"Comorbidity; Anhedonia; Anxiety; Context (archaeology); Depression (economics); Clinical psychology; Psychiatry; Personalized medicine; Precision medicine; Mental health; Biomarker; Medicine; Bipolar disorder; Psychology; Mood; Bioinformatics; Schizophrenia (object-oriented programming)","score_opus":0.2624980953264553,"score_gpt":0.35066340044963207,"score_spread":0.08816530512317677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186505697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93866867,0.0011804181,0.0003956367,0.05731225,0.0002051831,0.0015233409,0.0004945962,0.00009082583,0.00012909372],"genre_scores_gemma":[0.9880722,0.0006201048,0.00057534355,0.010396409,0.000011854278,0.000064270964,0.00018045683,0.00003304937,0.000046292153],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9963034,0.0015335317,0.0006723823,0.00055934105,0.00037581925,0.00055556424],"domain_scores_gemma":[0.99798214,0.0008349359,0.00024431892,0.0005114755,0.000038426275,0.00038870066],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00069672515,0.0002815131,0.00056452176,0.00016031253,0.00078618276,0.000093969225,0.00023698545,0.000084913736,0.00013724262],"category_scores_gemma":[0.0005454716,0.00030857357,0.00010623518,0.00049887365,0.00056246016,0.00020901847,0.00016579607,0.00031279834,0.000010076621],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053191406,0.012932408,0.03987329,0.0018743672,0.0000713487,0.000040699397,0.06730017,0.000015000553,0.16627075,0.0500612,0.02615597,0.6348729],"study_design_scores_gemma":[0.005126516,0.001442889,0.9380388,0.00038257337,0.000021432528,0.00019403921,0.013136888,0.00022473432,0.031472154,0.001691332,0.007404604,0.00086401025],"about_ca_topic_score_codex":0.0029563461,"about_ca_topic_score_gemma":0.008674816,"teacher_disagreement_score":0.8981655,"about_ca_system_score_codex":0.00013736474,"about_ca_system_score_gemma":0.00063997234,"threshold_uncertainty_score":0.99993664},"labels":[],"label_agreement":null},{"id":"W3186531624","doi":"10.1097/yct.0000000000000782","title":"The Pattern of Change in Depressive Symptoms and Inflammatory Markers After Electroconvulsive Therapy","year":2021,"lang":"en","type":"article","venue":"Journal of Ect","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean; Centre intégré de santé et de services sociaux de la Montérégie-Centre; Centre intégré de santé et de services sociaux de Chaudière-Appalaches; Montreal Children's Hospital; Institut Universitaire en Santé Mentale de Québec; Université Laval","funders":"","keywords":"Electroconvulsive therapy; Depression (economics); Inflammation; Major depressive disorder; Systematic review; MEDLINE; Correlation; Depressive symptoms; Mechanism (biology)","score_opus":0.01826512752152832,"score_gpt":0.2562467121353338,"score_spread":0.23798158461380547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186531624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99489564,0.0044144653,0.0000075335697,0.00037044418,0.00011069121,0.00008721886,0.000001431798,0.0000018769725,0.00011071669],"genre_scores_gemma":[0.99679464,0.002448756,0.000002543617,0.0006728374,0.000044848715,0.0000073031365,5.669327e-8,0.0000072205457,0.00002177378],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99924886,0.00015997236,0.00021747824,0.00009242739,0.00013896472,0.00014232458],"domain_scores_gemma":[0.99932635,0.00030125136,0.00020358698,0.00008904181,0.000049524973,0.000030236652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001356155,0.00007080569,0.00012767361,0.00006264388,0.000031912215,0.00003024303,0.000119734534,0.00003022365,0.00003274874],"category_scores_gemma":[0.00014915873,0.000045411485,0.00006197546,0.000120295364,0.000076758704,0.00014813466,0.000028235243,0.00016564211,9.2618546e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007724353,0.00012643605,0.21113664,0.00003367027,0.000059514867,0.0006380028,0.003026438,0.0000031933682,0.63587296,0.000059493817,0.00017145246,0.14809974],"study_design_scores_gemma":[0.001389537,0.00020457491,0.54411745,0.00008920119,0.0000041749745,0.00015443901,0.00019102103,0.000021231579,0.45269257,0.0002019549,0.0008541366,0.000079684665],"about_ca_topic_score_codex":0.00000410397,"about_ca_topic_score_gemma":0.000036644353,"teacher_disagreement_score":0.33298084,"about_ca_system_score_codex":0.0000138377745,"about_ca_system_score_gemma":0.000051678013,"threshold_uncertainty_score":0.18518266},"labels":[],"label_agreement":null},{"id":"W3187148885","doi":"10.21203/rs.3.rs-30473/v1","title":"A blood-based comprehensive and systems-level analysis of disease stages, immune regulation and symptoms in COVID-19 patients","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute of Cancer Research","funders":"","keywords":"Coronavirus disease 2019 (COVID-19); Immune system; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Disease; Medicine; Immunology; Virology; Infectious disease (medical specialty); Internal medicine","score_opus":0.10858613136168853,"score_gpt":0.3764802213272325,"score_spread":0.267894089965544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3187148885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943526,0.0015880446,0.00012545871,0.0005471952,0.000041526397,0.0016636453,0.0016176034,0.000038506438,0.000025437053],"genre_scores_gemma":[0.99898547,0.0002990407,0.000020064552,0.000115132956,0.000012158972,0.000118245014,0.00039183281,0.000023761588,0.000034286404],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99557865,0.0014067835,0.00048654448,0.00097118976,0.001173725,0.00038310423],"domain_scores_gemma":[0.99702936,0.0014088149,0.00021851507,0.0005728425,0.0002677869,0.0005026725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041859775,0.0002441165,0.0006105914,0.001408505,0.00014590294,0.0001802982,0.00032641343,0.00016184527,0.00002938986],"category_scores_gemma":[0.0029801659,0.0002393338,0.00012755806,0.0017207699,0.000475081,0.00009060949,0.00077393797,0.0005746599,0.0000017329096],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036082908,0.0021956537,0.8487168,0.033271927,0.0008472946,0.0002851042,0.0039918753,0.06457386,0.035691775,0.0029632892,0.00037651838,0.0034776183],"study_design_scores_gemma":[0.0023876338,0.00023457946,0.94561964,0.00061894656,0.00014624358,1.8015187e-7,0.00030762842,0.049231756,0.00061491824,0.0004843525,0.00008044817,0.00027366748],"about_ca_topic_score_codex":0.00082914974,"about_ca_topic_score_gemma":0.00006055363,"teacher_disagreement_score":0.096902855,"about_ca_system_score_codex":0.0001295733,"about_ca_system_score_gemma":0.0004836825,"threshold_uncertainty_score":0.975975},"labels":[],"label_agreement":null},{"id":"W3189026096","doi":"10.3389/fnbeh.2021.714810","title":"Sex-Specific Retinal Anomalies Induced by Chronic Social Defeat Stress in Mice","year":2021,"lang":"en","type":"article","venue":"Frontiers in Behavioral Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre intégré universitaire de santé et de services sociaux de la Capitale-Nationale; Université Laval; Centres Intégré Universitaires de Santé et de Services Sociaux","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Social defeat; Erg; Biomarker; Psychological resilience; Retinal; Retina; Psychology; Chronic stress; Physiology; Neuroscience; Biology; Developmental psychology; Medicine; Ophthalmology; Genetics; Social psychology","score_opus":0.04188849578031897,"score_gpt":0.28639967297563,"score_spread":0.24451117719531104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3189026096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964526,0.00038272465,0.00017285124,0.00041157,0.001776685,0.00025210454,0.000104465995,0.000078093384,0.00036885284],"genre_scores_gemma":[0.99828255,0.00017595552,0.00023982354,0.0005476078,0.000059597565,0.000035964586,0.000009175666,0.000031278058,0.00061804557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964665,0.00035560096,0.0004158229,0.0012733445,0.0006070074,0.0008816937],"domain_scores_gemma":[0.999382,0.00004428676,0.00011336544,0.00031224097,0.000025525384,0.00012257717],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016798046,0.0003028822,0.00035150565,0.000267038,0.0002890475,0.0002197671,0.0008354681,0.00015450994,0.000037179827],"category_scores_gemma":[0.00011952552,0.00034180374,0.000091482376,0.0018732232,0.00061347004,0.00053623336,0.00023645993,0.0005889713,0.000008748108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027018466,0.000447726,0.038429122,0.000010956802,1.537437e-7,0.00030030636,0.0005475202,0.000015385747,0.95058477,0.00009244491,0.0028805654,0.006664045],"study_design_scores_gemma":[0.0013256934,0.00021055863,0.07172977,0.00004195453,0.0000035861422,0.000033629585,0.0012415792,0.00027747903,0.9183581,0.00017629364,0.005986993,0.0006143518],"about_ca_topic_score_codex":0.000038063972,"about_ca_topic_score_gemma":0.000105039486,"teacher_disagreement_score":0.03330065,"about_ca_system_score_codex":0.00027465465,"about_ca_system_score_gemma":0.00020312055,"threshold_uncertainty_score":0.9999034},"labels":[],"label_agreement":null},{"id":"W3191545722","doi":"10.3389/fncel.2021.733997","title":"Editorial: The Crossroads Between Immunological Disorders and Neuropsychiatric Diseases. A Case for Schizophrenia","year":2021,"lang":"en","type":"editorial","venue":"Frontiers in Cellular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; Université Laval; Centre Hospitalier de l’Université de Montréal; University of British Columbia; McGill University","funders":"","keywords":"Schizophrenia (object-oriented programming); Psychiatry; Neuroscience; Medicine; Psychology","score_opus":0.011509672772389457,"score_gpt":0.25250356802605717,"score_spread":0.2409938952536677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3191545722","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0078314515,0.003397087,0.0028603552,0.0004518342,0.98309636,0.0013493664,0.00082554884,0.0001465554,0.000041440257],"genre_scores_gemma":[0.022987666,0.0036114866,0.00047094733,0.00031803697,0.9716014,0.00029174186,0.00008065043,0.00015982786,0.00047819258],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9933823,0.0007440854,0.00075282116,0.0025481423,0.0013507814,0.0012218676],"domain_scores_gemma":[0.9957419,0.002347211,0.0004183953,0.0011097353,0.00009350625,0.0002892374],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00058488076,0.0007849465,0.0008679385,0.00040771152,0.0012036655,0.00090632227,0.001959227,0.0008181493,0.000005002923],"category_scores_gemma":[0.010960925,0.0006261821,0.00036748388,0.001799815,0.0021697828,0.00035490727,0.00073788984,0.0020100272,0.0000029959426],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015043476,0.00015856445,0.00036638958,0.0001070646,0.000004718,0.0003477759,0.00007778922,0.000022460174,0.0026241844,0.000047601705,0.990902,0.005191012],"study_design_scores_gemma":[0.001976199,0.00029299414,0.00022814382,0.000037794194,0.000068329085,0.000027028107,0.00010476634,0.00053647003,0.00042487652,0.0018393109,0.9936853,0.00077877735],"about_ca_topic_score_codex":0.000042761898,"about_ca_topic_score_gemma":0.000020476135,"teacher_disagreement_score":0.015156213,"about_ca_system_score_codex":0.000097146534,"about_ca_system_score_gemma":0.00063054374,"threshold_uncertainty_score":0.99961895},"labels":[],"label_agreement":null},{"id":"W3191927178","doi":"10.1016/j.bbih.2021.100308","title":"Beyond the neuro-immune interplay in depression: Could gut microbes be the missing link?","year":2021,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Weston Family Foundation","keywords":"Gut–brain axis; Gut flora; Immune system; Context (archaeology); Depression (economics); Neuroscience; Gastrointestinal tract; Biology; Immunology","score_opus":0.045242449245509034,"score_gpt":0.34372097006273855,"score_spread":0.29847852081722953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3191927178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8519429,0.002939963,0.000043870303,0.1425696,0.0007650906,0.0007769579,0.00004707982,0.000113801674,0.0008007667],"genre_scores_gemma":[0.9298395,0.00037599693,0.00011788006,0.068654984,0.00007402485,0.000071978975,0.000029863051,0.000054729808,0.00078103953],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9952051,0.0023158723,0.00069975964,0.00056561426,0.00042928793,0.00078437844],"domain_scores_gemma":[0.9959109,0.002147021,0.00026711012,0.0014623968,0.000056520767,0.00015607927],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0011820429,0.0003272856,0.00037871074,0.00011578429,0.0015183493,0.00027652588,0.0012680835,0.00014840314,0.00023833074],"category_scores_gemma":[0.0016243757,0.00022298117,0.00018342327,0.00090844743,0.0005131563,0.00021361926,0.0006024149,0.0017001649,0.000028641594],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000783117,0.0008727472,0.0037344114,0.00007120783,0.000005527972,0.00017422081,0.008544857,0.000015302643,0.84469265,0.00066657225,0.009819404,0.13132481],"study_design_scores_gemma":[0.0031162882,0.00030501038,0.6389449,0.00046789207,0.000033630648,0.0008687069,0.007723489,0.00020859273,0.2198228,0.0010425537,0.1265222,0.000943911],"about_ca_topic_score_codex":0.0010310728,"about_ca_topic_score_gemma":0.000855974,"teacher_disagreement_score":0.6352105,"about_ca_system_score_codex":0.0001199592,"about_ca_system_score_gemma":0.000600508,"threshold_uncertainty_score":0.99978155},"labels":[],"label_agreement":null},{"id":"W3192479465","doi":"10.1016/j.drudis.2021.07.027","title":"Positive AMPA receptor modulation in the treatment of neuropsychiatric disorders: A long and winding road","year":2021,"lang":"en","type":"review","venue":"Drug Discovery Today","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"National Institutes of Health","keywords":"AMPA receptor; Glutamatergic; Neuroscience; Drug discovery; Isoxazole; Drug development; Drug; Antidepressant; Pharmacology; Glutamate receptor; Receptor; Medicine; Biology; Bioinformatics; Hippocampus; Chemistry; Internal medicine","score_opus":0.027146879422346573,"score_gpt":0.29823537772097,"score_spread":0.2710884982986234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3192479465","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03317779,0.96424127,0.00002387712,0.00017096558,0.00039408356,0.0012436645,0.00015662551,0.000017426715,0.00057430146],"genre_scores_gemma":[0.033525575,0.9657802,0.000010930703,0.00007433112,0.00008365872,0.00008367866,0.00009330604,0.000039295763,0.00030901353],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99739546,0.00086801534,0.00047956783,0.000685882,0.0002884925,0.00028259915],"domain_scores_gemma":[0.99858624,0.0006562329,0.0003191797,0.0003910469,0.000008991692,0.000038311973],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012924982,0.00040101437,0.0008732816,0.00026893287,0.00010902695,0.00016581864,0.0002768886,0.00010123088,0.00001749866],"category_scores_gemma":[0.00011254945,0.00026012515,0.00037425567,0.0010108176,0.00011743962,0.0003294832,0.00005223693,0.00018698315,0.00000806695],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013166982,0.00071573,0.0001492757,0.0009531075,0.000024563737,0.000017552256,0.0022033597,0.000020868429,0.000021441656,0.0006331133,0.000088031906,0.9951598],"study_design_scores_gemma":[0.0044630175,0.001457895,0.015328992,0.018953027,0.0010567143,0.00014279466,0.0037947432,0.0002543984,0.00036406686,0.0009174413,0.95003235,0.0032345334],"about_ca_topic_score_codex":0.00008182091,"about_ca_topic_score_gemma":0.00010266714,"teacher_disagreement_score":0.99192524,"about_ca_system_score_codex":0.000086266526,"about_ca_system_score_gemma":0.00011371791,"threshold_uncertainty_score":0.9999851},"labels":[],"label_agreement":null},{"id":"W3193434494","doi":"10.1007/s00702-021-02394-0","title":"Changes in RNA expression levels during antidepressant treatment: a systematic review","year":2021,"lang":"en","type":"review","venue":"Journal of Neural Transmission","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation; International OCD Foundation; Physicians' Services Incorporated Foundation; Ontario Brain Institute; Brain and Behavior Research Foundation","keywords":"Antidepressant; Meta-analysis; Placebo; Medicine; Bioinformatics; Oncology; Psychology; Internal medicine; Psychiatry; Biology; Anxiety; Pathology; Alternative medicine","score_opus":0.11208267803765888,"score_gpt":0.3552883980337074,"score_spread":0.2432057199960485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3193434494","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00030209817,0.99791133,0.000011272989,0.00019337762,0.00022295219,0.0012707118,0.000014047803,0.000019196903,0.000055038116],"genre_scores_gemma":[0.00054042495,0.99890924,0.000041241146,0.00011289929,0.00009125409,0.000038979735,0.0000022226707,0.00005842565,0.0002053384],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.99540997,0.0014386845,0.0017002968,0.0004581548,0.00062066544,0.0003722039],"domain_scores_gemma":[0.99744326,0.00048699084,0.0014442115,0.00036652808,0.00004572969,0.00021325694],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030893282,0.0005632772,0.003878325,0.00043942753,0.00009855549,0.000069826376,0.0005566227,0.00020647186,0.00013514605],"category_scores_gemma":[0.00041107796,0.0003184768,0.0011126766,0.0006554108,0.000035934314,0.00024611191,0.000041286792,0.00059552304,0.0000060509624],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012536164,0.00020639344,1.7423284e-7,0.8305844,0.000023017245,0.0018367904,0.00008613148,0.0000019765826,0.015696222,0.0000013745912,0.00002873352,0.15152222],"study_design_scores_gemma":[0.0006642684,0.00017238897,0.0000029298903,0.9589369,0.000544772,0.0020113562,0.00001607591,0.00000614634,0.0126074115,0.0000039525335,0.024715846,0.0003179361],"about_ca_topic_score_codex":9.913069e-7,"about_ca_topic_score_gemma":0.0000010536854,"teacher_disagreement_score":0.15120429,"about_ca_system_score_codex":0.00014099677,"about_ca_system_score_gemma":0.00015751769,"threshold_uncertainty_score":0.99992675},"labels":[],"label_agreement":null},{"id":"W3193539820","doi":"10.17116/jnevro202112105284","title":"Depression in the structure of schizophrenia: clinical and biochemical characteristics","year":2021,"lang":"en","type":"article","venue":"S S Korsakov Journal of Neurology and Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Psychopathology; Schizophrenia (object-oriented programming); Depression (economics); Internal medicine; Neurocognitive; Brain-derived neurotrophic factor; Positive and Negative Syndrome Scale; Psychology; Psychiatry; Psychosis; Clinical psychology; Medicine; Neurotrophic factors; Cognition; Receptor","score_opus":0.01586600410691713,"score_gpt":0.2867009233022408,"score_spread":0.27083491919532365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3193539820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99296284,0.0012891518,0.000009552276,0.0048531797,0.0007972006,0.000035668647,0.000008898484,0.0000021555422,0.000041383708],"genre_scores_gemma":[0.9950894,0.0007227885,0.0001999906,0.0037826572,0.00019718004,1.111317e-7,4.902545e-7,0.0000052759974,0.0000020882999],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99871385,0.00042907742,0.0004393785,0.00018027272,0.000119105396,0.000118315234],"domain_scores_gemma":[0.9991614,0.00039403662,0.0002390148,0.00012537309,0.000026842872,0.000053304724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018870573,0.00008819711,0.0002341679,0.000060468705,0.000049276252,0.000013572495,0.00016533428,0.00015598098,0.000017143751],"category_scores_gemma":[0.00043739754,0.00005749061,0.000060459497,0.00013599961,0.00032357493,0.0000528982,0.000049962662,0.0007059238,2.4591523e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001713699,0.00032780474,0.8228071,0.000059975562,0.000014472479,0.00020933502,0.00026034808,0.0000012362729,0.16668896,0.0018784392,0.0011002248,0.004938448],"study_design_scores_gemma":[0.0019000128,0.0003699036,0.97460806,0.00003401196,0.00002210008,0.0028946,0.00006725582,0.000017924702,0.00895745,0.010549871,0.00049593794,0.00008286239],"about_ca_topic_score_codex":3.7221915e-7,"about_ca_topic_score_gemma":0.0000039682036,"teacher_disagreement_score":0.1577315,"about_ca_system_score_codex":5.241511e-7,"about_ca_system_score_gemma":0.0000698596,"threshold_uncertainty_score":0.30669272},"labels":[],"label_agreement":null},{"id":"W3193976003","doi":"10.3389/fphar.2021.744290","title":"Editorial: Targeting the Chemoattractant System in Inflammation","year":2021,"lang":"en","type":"editorial","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Inflammation; Chemotaxis; Medicine; Pharmacology; Cancer research; Immunology; Receptor; Internal medicine","score_opus":0.008873853341176158,"score_gpt":0.2683672074097815,"score_spread":0.2594933540686053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3193976003","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013006255,0.00083475455,0.00007427567,0.00035302856,0.9956738,0.00064402766,0.000034834142,0.000094102244,0.0009905737],"genre_scores_gemma":[0.004994824,0.00072948146,0.00012237241,0.00013258083,0.9934087,0.00023337509,0.000078573255,0.00006092889,0.00023915648],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99606955,0.0009853509,0.00074084377,0.00080271997,0.0007405864,0.0006609625],"domain_scores_gemma":[0.9978536,0.0013458198,0.00039630674,0.00024884887,0.000089020774,0.00006644573],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010259341,0.00036838042,0.000623416,0.000336953,0.0001313543,0.00008460192,0.0008660119,0.0010344764,0.000046291494],"category_scores_gemma":[0.0023462488,0.00031853226,0.00011792058,0.00072453095,0.00019637447,0.0001796271,0.00019354727,0.0022412906,0.000019277933],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119351615,0.00005091555,0.000027046632,0.00018610066,0.000012120426,0.00012234098,0.00035864688,0.00013099864,0.034845,0.000022866216,0.9634307,0.00069392996],"study_design_scores_gemma":[0.0016100191,0.000021627577,0.000005484886,0.00008752575,0.000019381008,0.0000015156132,0.0006232709,0.0006465354,0.0316779,0.00006781074,0.96494067,0.00029826968],"about_ca_topic_score_codex":0.00003618564,"about_ca_topic_score_gemma":0.000021327904,"teacher_disagreement_score":0.0036941986,"about_ca_system_score_codex":0.0006917222,"about_ca_system_score_gemma":0.000575327,"threshold_uncertainty_score":0.9999267},"labels":[],"label_agreement":null},{"id":"W3194390221","doi":"10.1016/j.ibneur.2021.08.002","title":"Effect of ketamine on the physiological responses to combined hypoglycemic and psychophysical stress","year":2021,"lang":"en","type":"article","venue":"IBRO Neuroscience Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Government of Ontario; Ontario Brain Institute","keywords":"Ketamine; Corticosterone; Stressor; Endocrinology; Internal medicine; Tumor necrosis factor alpha; Immune system; Fight-or-flight response; Hypoglycemia; Cytokine; Medicine; Psychology; Hormone; Neuroscience; Anesthesia; Chemistry; Insulin; Immunology","score_opus":0.02934134153956689,"score_gpt":0.29971626554762565,"score_spread":0.27037492400805874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3194390221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99719495,0.000011789454,0.000011420204,0.0013039387,0.00042825178,0.00031700128,0.000008954911,0.000052608404,0.00067106396],"genre_scores_gemma":[0.99708354,0.000020767833,0.00000763078,0.0024687347,0.000026743452,0.000025500252,4.973432e-7,0.000011204554,0.00035535678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975314,0.00053633447,0.0002770762,0.00084023824,0.0004980086,0.00031690596],"domain_scores_gemma":[0.9975715,0.0015054771,0.00013766909,0.0006181432,0.00002800584,0.00013918035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027625496,0.00018668298,0.00026203017,0.00006237295,0.00018725204,0.000067406116,0.00025235643,0.00004248114,0.000016003229],"category_scores_gemma":[0.0073751314,0.00011231412,0.00008640514,0.00075624284,0.0005581727,0.000083093626,0.00019401223,0.00017701805,0.0000059460203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026444573,0.00018419967,0.0006361487,0.000015188468,5.231182e-7,0.00046557057,0.000032494638,0.000026513266,0.9967286,0.0004647402,0.00023446884,0.0009471038],"study_design_scores_gemma":[0.00022812847,0.0016760008,0.047295745,0.000036243855,0.0000034654845,0.00020815199,0.000011478079,0.000099800425,0.94961685,0.00043251904,0.00026656472,0.00012502943],"about_ca_topic_score_codex":0.0000023250168,"about_ca_topic_score_gemma":4.763907e-7,"teacher_disagreement_score":0.04711173,"about_ca_system_score_codex":0.000008207251,"about_ca_system_score_gemma":0.000048990776,"threshold_uncertainty_score":0.8829254},"labels":[],"label_agreement":null},{"id":"W3195347857","doi":"10.52571/ptq.v17.n36.2020.1163_periodico36_pgs_1147_1159.pdf","title":"CHANGE IN BLOOD CHEMISTRY, PRO-INFLAMMATORY CYTOKINES, AND APOPTOTIC GENES FOLLOWING METHAMPHETAMINE USE IN EXPERIMENTAL RATS","year":2020,"lang":"en","type":"article","venue":"PERIÓDICO TCHÊ QUÍMICA","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Shiraz University; Shiraz University of Medical Sciences; Islamic Azad University","keywords":"Meth-; Methamphetamine; White blood cell; Pharmacology; Proinflammatory cytokine; Medicine; Xanthine oxidase; Chemistry; Immunology; Physiology; Inflammation; Biochemistry; Enzyme","score_opus":0.05659356371729425,"score_gpt":0.27572465563531945,"score_spread":0.2191310919180252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195347857","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99729705,0.0012097835,0.0000022334864,0.0006411305,0.000085758285,0.0005085509,0.0000073655465,0.00010401748,0.0001441279],"genre_scores_gemma":[0.99813956,0.00013813068,0.00016584115,0.0012051924,0.00010615563,0.00015198502,0.000005856825,0.000042427553,0.000044875822],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814916,0.00009792942,0.00033297177,0.00071682566,0.00026336836,0.00043975248],"domain_scores_gemma":[0.9994155,0.0001062096,0.000072680006,0.00021423814,0.000007224793,0.00018412928],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000094411625,0.00028264304,0.00033106573,0.00008239714,0.00006732841,0.0000943495,0.00025712093,0.00010684075,0.0001132689],"category_scores_gemma":[0.00031813458,0.0002884993,0.00008320329,0.0004286233,0.0001260493,0.0003943163,0.0001909874,0.00020501432,0.000013718075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057215533,0.00015540946,0.01742449,0.000070915245,0.0000053593285,0.00021356992,0.0028174608,0.0000028812867,0.9784437,0.00002205806,0.000011277873,0.00077565014],"study_design_scores_gemma":[0.0019506078,0.00006879978,0.01308246,0.000048871825,0.000008225603,0.000018443608,0.00043246264,0.00075289427,0.98245704,0.000009660484,0.0008200506,0.00035050706],"about_ca_topic_score_codex":0.00009730367,"about_ca_topic_score_gemma":0.000052862688,"teacher_disagreement_score":0.004342031,"about_ca_system_score_codex":0.00004028074,"about_ca_system_score_gemma":0.000041015228,"threshold_uncertainty_score":0.9999567},"labels":[],"label_agreement":null},{"id":"W3196010156","doi":"10.1016/j.bbih.2021.100324","title":"Prolonged saturated, but not monounsaturated, high-fat feeding provokes anxiodepressive-like behaviors in female mice despite similar metabolic consequences","year":2021,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"Nucleus accumbens; Leptin; Endocrinology; Internal medicine; Anxiety; Inflammation; Obesity; Elevated plus maze; Behavioural despair test; Medicine; Saturated fat; Antidepressant; Cholesterol; Psychiatry; Central nervous system","score_opus":0.04739485731081276,"score_gpt":0.3119278052175575,"score_spread":0.2645329479067447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196010156","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98953617,0.0021878337,0.000012633665,0.0045932382,0.000878792,0.0020042164,0.0002956997,0.00038947,0.00010194171],"genre_scores_gemma":[0.9898648,0.0008370891,0.0009608097,0.0068764803,0.000074828386,0.00044497417,0.00014956998,0.000105194944,0.00068621716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.992605,0.0023894813,0.0011966497,0.0014072622,0.0008084381,0.0015931743],"domain_scores_gemma":[0.99687546,0.00072411273,0.0006421945,0.0010560302,0.00023483962,0.00046737588],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009863997,0.0007364706,0.0010781555,0.0005054031,0.0011409584,0.00041533302,0.0010453308,0.00040283523,0.00021480698],"category_scores_gemma":[0.0012596084,0.0007505942,0.00023075288,0.002014421,0.0008256646,0.0008946801,0.0003394779,0.0017768465,0.0000695855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022838326,0.0010704754,0.007393178,0.00011254087,0.000011691351,0.00045084342,0.0032035336,0.0000435545,0.980131,0.00049710646,0.0003947006,0.0064630285],"study_design_scores_gemma":[0.002940401,0.00031696272,0.24582562,0.00026058254,0.000059888134,0.00031224894,0.00505923,0.000035361667,0.7427377,0.00012692127,0.0012854234,0.0010396345],"about_ca_topic_score_codex":0.00551094,"about_ca_topic_score_gemma":0.0024602036,"teacher_disagreement_score":0.23843244,"about_ca_system_score_codex":0.00029675153,"about_ca_system_score_gemma":0.0012934682,"threshold_uncertainty_score":0.9994945},"labels":[],"label_agreement":null},{"id":"W3196396184","doi":"10.1017/s0033291721003767","title":"Impact of data extraction errors in meta-analyses on the association between depression and peripheral inflammatory biomarkers: an umbrella review","year":2021,"lang":"en","type":"article","venue":"Psychological Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health; Ottawa Hospital; University of Ottawa","funders":"Centro de Investigación Biomédica en Red de Salud Mental; Department of Psychiatry, University of Toronto; Karolinska Institutet; National Research Foundation of Korea; University of Toronto; Universidade de São Paulo; Università degli Studi di Pavia; National Research Foundation","keywords":"Depression (economics); Association (psychology); Data extraction; Peripheral; MEDLINE; Extraction (chemistry)","score_opus":0.4252150601923386,"score_gpt":0.510162309496301,"score_spread":0.08494724930396241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196396184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867279,0.0069779414,0.000036026733,0.0046574324,0.00006010413,0.00021465057,0.000020769836,0.00001961466,0.0012855568],"genre_scores_gemma":[0.99349,0.0046294634,0.00004464533,0.0017123485,0.00005341352,0.000008485929,0.000026518423,0.000005913945,0.000029237166],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9975995,0.0010301104,0.00037551456,0.0004841241,0.00035899377,0.00015177233],"domain_scores_gemma":[0.99792135,0.0011705086,0.0002535825,0.00055345095,0.000031097145,0.000070022856],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011848204,0.00013381966,0.0004354434,0.000051443636,0.000048531652,0.000010256167,0.00028272095,0.00008823694,0.0009315804],"category_scores_gemma":[0.0051552993,0.00006151705,0.000087392145,0.00039137824,0.00012682847,0.00017063026,0.00006094357,0.00023032718,0.0000033407161],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035712254,0.0012452136,0.14366014,0.000330552,0.0011349055,0.00012221042,0.00040850963,0.0000191984,0.6850814,0.00017421714,0.016313301,0.15115322],"study_design_scores_gemma":[0.00066907494,0.0003669716,0.9952716,0.00028861908,0.00044456293,0.000012180324,0.00008310488,0.000071395996,0.001885502,0.00037304577,0.00042341245,0.00011048552],"about_ca_topic_score_codex":0.000027229415,"about_ca_topic_score_gemma":0.000010773151,"teacher_disagreement_score":0.8516115,"about_ca_system_score_codex":0.00003272733,"about_ca_system_score_gemma":0.0000082788265,"threshold_uncertainty_score":0.9999817},"labels":[],"label_agreement":null},{"id":"W3196430494","doi":"10.7150/thno.60679","title":"Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma","year":2021,"lang":"en","type":"article","venue":"Theranostics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Common Fund; NIH Office of the Director; Bundesministerium für Bildung und Forschung; Deutsches Krebsforschungszentrum; Deutsche Forschungsgemeinschaft; Deutscher Akademischer Austauschdienst; National Institutes of Health; Universitätsklinikum Heidelberg; Ministère de l'Économie, de la Science et de l'Innovation - Québec; European Commission","keywords":"Aryl hydrocarbon receptor; Kynurenine; Metabolite; Catabolism; Metabolism; Cancer research; Tryptophan; Chemistry; Kynurenine pathway; Tumor progression; Tumor microenvironment; Internal medicine; Biology; Biochemistry; Medicine; Amino acid; Gene; Tumor cells; Transcription factor","score_opus":0.009763529848349588,"score_gpt":0.20561318698170958,"score_spread":0.19584965713336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196430494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990867,0.00016318381,0.000007929243,0.0002354351,0.000045456836,0.00020308714,0.000026533799,0.00003586408,0.00019585049],"genre_scores_gemma":[0.99748284,0.000038235496,0.00009343546,0.0023131606,0.000011416189,0.0000045955035,0.0000013242035,0.000025063455,0.000029939216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990776,0.00014044748,0.00015392105,0.00021242663,0.00025162712,0.00016396886],"domain_scores_gemma":[0.9994063,0.0002086863,0.000069938484,0.00023578954,0.00004799782,0.0000312901],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005587421,0.00011358353,0.0001553787,0.0000496495,0.000033323817,0.000024871773,0.00016028914,0.000027522263,0.000027218464],"category_scores_gemma":[0.00020552524,0.00007422288,0.000024122584,0.0004748508,0.00017226285,0.000060387098,0.00003333536,0.00010225947,0.0000017992412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019215171,0.0038259404,0.036034696,0.0002281702,0.00012525459,0.0005631845,0.028895535,0.00007155829,0.8963817,0.020787518,0.0009469372,0.010217993],"study_design_scores_gemma":[0.004183321,0.00023849671,0.22393927,0.000039002254,0.000041911444,0.000020147856,0.00048057022,0.00008835828,0.7676013,0.0014295058,0.0017476587,0.00019046258],"about_ca_topic_score_codex":0.0000068771756,"about_ca_topic_score_gemma":0.00001952388,"teacher_disagreement_score":0.18790457,"about_ca_system_score_codex":0.0000029202165,"about_ca_system_score_gemma":0.000032567168,"threshold_uncertainty_score":0.30267212},"labels":[],"label_agreement":null},{"id":"W3196474089","doi":"10.3389/fimmu.2021.725204","title":"Targeting Indoleamine 2,3-Dioxygenase 1: Fighting Cancers via Dormancy Regulation","year":2021,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Chengdu University; Chengdu University of Traditional Chinese Medicine; Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; Jiangxi University of Traditional Chinese Medicine; Mitacs; China Postdoctoral Science Foundation","keywords":"Dormancy; Indoleamine 2,3-dioxygenase; Kynurenine; Aryl hydrocarbon receptor; Cancer research; Metastasis; Kynurenine pathway; Biology; Cancer; Medicine; Internal medicine; Tryptophan; Biochemistry; Botany; Gene; Transcription factor; Germination","score_opus":0.02377853747860601,"score_gpt":0.27699681119334624,"score_spread":0.2532182737147402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196474089","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001027413,0.99294674,0.0016491367,0.000023550541,0.0038057982,0.0005838198,0.000023117878,0.000103637016,0.0007614304],"genre_scores_gemma":[0.0001052294,0.9968992,0.0015563394,0.00011782282,0.00017965825,0.00010309809,0.00018044199,0.00008579796,0.0007724101],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99640834,0.0007653398,0.0009317533,0.00095436495,0.0002043863,0.0007357987],"domain_scores_gemma":[0.99856323,0.00023033627,0.0005906068,0.00053041405,0.000032005875,0.000053378317],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024311863,0.0005157752,0.0016879106,0.0007314538,0.00015715233,0.00004805689,0.0006417941,0.00061690965,0.00017933657],"category_scores_gemma":[0.0008161185,0.0005033569,0.00031957182,0.0013141216,0.00023482295,0.0001891639,0.00023408899,0.0009524537,0.00006569307],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001274892,0.000042456297,0.0000054770867,0.0014770335,0.000058120462,0.000104706676,0.0001493598,0.000042381194,0.0007667959,0.00010861648,0.006528117,0.9907042],"study_design_scores_gemma":[0.00047279906,0.00003749074,0.000010820117,0.0030949549,0.00002747208,0.00005738311,0.0001271838,0.00020977981,0.0009199587,0.00014122472,0.99434453,0.0005564167],"about_ca_topic_score_codex":0.000045027093,"about_ca_topic_score_gemma":0.000009834318,"teacher_disagreement_score":0.99014777,"about_ca_system_score_codex":0.0006444663,"about_ca_system_score_gemma":0.00043621173,"threshold_uncertainty_score":0.9997418},"labels":[],"label_agreement":null},{"id":"W3197284381","doi":"10.3233/ch-219109","title":"Utility of intestinal intravital microscopy for the study of CNS injury-induced immunodepression syndrome (CIDS)","year":2021,"lang":"en","type":"article","venue":"Clinical Hemorheology and Microcirculation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Intravital microscopy; Microcirculation; Inflammation; Immune system; Medicine; Pathology; Stroke (engine); Central nervous system; Immunology; Internal medicine","score_opus":0.07049364490187529,"score_gpt":0.38206947842140504,"score_spread":0.3115758335195298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197284381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963735,0.00016250744,0.0024484803,0.00013816601,0.0003377183,0.00047636474,0.00001835179,0.000014160247,0.000030795432],"genre_scores_gemma":[0.9995514,0.000027776014,0.00017617957,0.00016445098,0.000019228264,0.000011677594,0.0000073026267,0.000008016162,0.000033964076],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99840647,0.0003293621,0.00062280893,0.00039380006,0.00008220669,0.00016536008],"domain_scores_gemma":[0.99726975,0.0020382355,0.00025745347,0.00029268404,0.00010830783,0.000033599033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044841508,0.00010805762,0.00031864192,0.00003144561,0.00015841167,0.00000803612,0.00016112391,0.00015207604,0.00004249413],"category_scores_gemma":[0.0018554822,0.00008369076,0.00010430886,0.00015828965,0.00037813862,0.00006496002,0.00013723045,0.0002350683,0.0000015693626],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041238597,0.0011574276,0.07773656,0.000051186667,0.000023308965,0.0000047699327,0.00040038655,0.0000015697768,0.90719265,0.00047435024,0.000036465168,0.012508952],"study_design_scores_gemma":[0.0021303,0.00071933813,0.610341,0.000031608197,0.0000489759,0.0000680235,0.00081010035,0.0007846718,0.38346317,0.0014683367,0.000037289778,0.00009717172],"about_ca_topic_score_codex":0.000013333091,"about_ca_topic_score_gemma":0.000017551856,"teacher_disagreement_score":0.53260446,"about_ca_system_score_codex":0.000003888095,"about_ca_system_score_gemma":0.00007544208,"threshold_uncertainty_score":0.341281},"labels":[],"label_agreement":null},{"id":"W3197334366","doi":"10.20944/preprints202109.0159.v1","title":"Inflammation and Nitro-Oxidative Stress in Current Suicidal Attempts and Current Suicidal Ideation: a Systematic Review and Meta-Analysis","year":2021,"lang":"en","type":"review","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Chulalongkorn University","keywords":"Meta-analysis; Inflammation; Immune system; Suicidal ideation; Oxidative stress; Internal medicine; Neurotoxicity; Confidence interval; Medicine; Oncology; Immunology; Poison control; Toxicity; Injury prevention","score_opus":0.27673838054095035,"score_gpt":0.4263239904966432,"score_spread":0.14958560995569287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197334366","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031822475,0.9932882,0.000024733683,0.00012277823,0.000060335944,0.0031187572,0.00011163873,0.00003667366,0.000054639033],"genre_scores_gemma":[0.008474509,0.99038106,0.0000081802245,0.00004639566,0.000024229954,0.0008763158,0.000079228055,0.000028640761,0.00008141159],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9945357,0.0018546274,0.0014457152,0.0013722175,0.00047387733,0.00031787727],"domain_scores_gemma":[0.9972931,0.00072911906,0.00096316024,0.0007582458,0.000095776566,0.00016057826],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010147172,0.00061653997,0.0047247796,0.00048061798,0.000110488385,0.000104973005,0.00031965872,0.00013710432,0.00022700835],"category_scores_gemma":[0.0018463181,0.0004757345,0.0006810202,0.0011975497,0.00015654546,0.00028542324,0.0005675932,0.0005623256,0.000048576847],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003213755,0.00013925917,0.0022349774,0.9769395,0.0061621773,0.000016989445,0.00040452753,0.0000031870102,0.000027556622,0.00041226318,0.000005505156,0.013650828],"study_design_scores_gemma":[0.0011218868,0.00005972347,0.0038002701,0.14986125,0.8217236,0.00014929203,0.00024683174,0.000111626,0.0012727819,0.0003308855,0.018192569,0.0031292944],"about_ca_topic_score_codex":0.000033895525,"about_ca_topic_score_gemma":0.00011719709,"teacher_disagreement_score":0.8270783,"about_ca_system_score_codex":0.00007910622,"about_ca_system_score_gemma":0.00010964822,"threshold_uncertainty_score":0.99976945},"labels":[],"label_agreement":null},{"id":"W3197382311","doi":"10.1096/fj.202100702r","title":"Tryptophan‐derived serotonin‐kynurenine balance in immune activation and intestinal inflammation","year":2021,"lang":"en","type":"review","venue":"The FASEB Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":117,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Kynurenine; Kynurenine pathway; Immune system; Inflammation; Biology; Serotonin; Immunology; Indoleamine 2,3-dioxygenase; Tryptophan; Biochemistry; Receptor","score_opus":0.04420822823042711,"score_gpt":0.30145940197921195,"score_spread":0.2572511737487848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197382311","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.023221016,0.9747666,0.00026119107,0.00039425882,0.0003128704,0.0006614678,0.000007097229,0.000036080444,0.00033941472],"genre_scores_gemma":[0.009797558,0.98944795,0.00011358792,0.00008347236,0.00028859518,0.000042929914,0.000015741567,0.00003639432,0.00017376857],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99757487,0.00076502707,0.0006853439,0.0003338247,0.00032187876,0.00031907918],"domain_scores_gemma":[0.9983707,0.00057195284,0.00066394254,0.00026580886,0.00004648646,0.00008111887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048769917,0.0003388195,0.0007756269,0.000226842,0.00025775834,0.00025280195,0.0004413389,0.00015206773,0.00013323697],"category_scores_gemma":[0.001100331,0.00022687588,0.00019652597,0.0005765053,0.0001479274,0.0002932129,0.00012587725,0.0012145566,0.00002002562],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002774237,0.000046083023,0.000011340547,0.0009528039,0.000020532889,0.000099225705,0.00030809,0.000012405524,0.1325066,0.00041662235,0.000050234943,0.8655483],"study_design_scores_gemma":[0.005226414,0.0004531103,0.0016136356,0.077694535,0.00036975535,0.014113897,0.00070866954,0.000736418,0.39947134,0.0019481508,0.49515843,0.0025056268],"about_ca_topic_score_codex":0.0000055503865,"about_ca_topic_score_gemma":0.0000031178201,"teacher_disagreement_score":0.8630427,"about_ca_system_score_codex":0.00011296732,"about_ca_system_score_gemma":0.00026518555,"threshold_uncertainty_score":0.92517304},"labels":[],"label_agreement":null},{"id":"W3198101346","doi":"10.1016/j.bbi.2021.08.228","title":"Behavioural adaptations after antibiotic treatment in male mice are reversed by activation of the aryl hydrocarbon receptor","year":2021,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; Hotchkiss Brain Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Aryl hydrocarbon receptor; ABX test; Open field; Elevated plus maze; Behavioural despair test; Biology; Endocrinology; Internal medicine; Psychology; Anxiety; Medicine; Gene; Biochemistry; Transcription factor","score_opus":0.030397680182589076,"score_gpt":0.254590376312334,"score_spread":0.22419269612974493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198101346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986181,0.00009022402,0.0000022048328,0.00064826396,0.00008735524,0.00030101393,0.00009188051,0.000013151127,0.00014775324],"genre_scores_gemma":[0.99855965,0.00005508618,0.000029802208,0.00026230127,0.000004522022,0.000029461085,0.00002219777,0.000010876293,0.0010260806],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99911046,0.00021528394,0.00018156807,0.00021297779,0.00012660968,0.00015308203],"domain_scores_gemma":[0.99944806,0.00013722501,0.00009281153,0.0002653301,0.000022105609,0.000034492747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059605907,0.00012300465,0.00014105624,0.000046744335,0.00012190312,0.000023942106,0.0001095306,0.00006747005,0.00010016486],"category_scores_gemma":[0.00017348654,0.00010025927,0.00006619843,0.000321672,0.00013146468,0.0001374617,0.000054698095,0.00014437365,0.000002474223],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031697087,0.0005752826,0.112987414,0.0000068181357,0.0000015334477,0.00000491637,0.0006388993,8.168483e-7,0.8840839,0.000010834603,0.00013684107,0.0015210324],"study_design_scores_gemma":[0.00050121726,0.00003667292,0.5399975,0.000031999458,0.000009927622,0.0000059479503,0.0007461438,0.0000070240053,0.4584963,0.0000054980546,0.0000914362,0.00007035507],"about_ca_topic_score_codex":0.0005985717,"about_ca_topic_score_gemma":0.00030132988,"teacher_disagreement_score":0.4270101,"about_ca_system_score_codex":0.00005722853,"about_ca_system_score_gemma":0.000048736834,"threshold_uncertainty_score":0.40884542},"labels":[],"label_agreement":null},{"id":"W3198782994","doi":"10.2174/1568026621666210909160210","title":"Investigation of the Relationship among Cortisol, Pro-inflammatoryCytokines, and the Degradation of Tryptophan into Kynurenine inPatients with Major Depression and Suicidal Behavior","year":2021,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; McGill University Health Centre","funders":"","keywords":"Major depressive disorder; Proinflammatory cytokine; Kynurenine; Internal medicine; Depression (economics); Endocrinology; Medicine; Inflammation; Tryptophan; Psychology; Chemistry; Amygdala; Biochemistry","score_opus":0.02827212171219867,"score_gpt":0.26852991844353896,"score_spread":0.2402577967313403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198782994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987658,0.0005892957,0.00003373839,0.00022860401,0.00008374825,0.00022795591,0.0000027336553,0.0000057954144,0.000062272964],"genre_scores_gemma":[0.9997467,0.000043811462,0.000051895175,0.0000180977,0.000030209598,0.000031160656,0.000009700706,0.0000051885513,0.000063257554],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990674,0.00008786944,0.00027245266,0.00019717358,0.00029174227,0.0000833229],"domain_scores_gemma":[0.999355,0.00016548263,0.00021226716,0.0001789926,0.000049518407,0.000038721515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011575115,0.00009248799,0.00013567109,0.000020849433,0.00007670236,0.000009765497,0.00011306855,0.000055376157,0.0000062106633],"category_scores_gemma":[0.0008252249,0.000054692788,0.000018444396,0.0002309651,0.0007290497,0.000073418116,0.0000725365,0.00020997383,3.23524e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054036136,0.000025660032,0.8683013,0.00025097615,0.000001379628,0.0000016652449,0.00053585845,0.0000012378807,0.12838764,0.00026487678,0.000008062482,0.0021673099],"study_design_scores_gemma":[0.0012520734,0.000012135951,0.54017055,0.00021684507,0.000017153718,0.0000081677545,0.00014763814,0.000060950766,0.45760146,0.00046148014,0.0000079231195,0.000043656953],"about_ca_topic_score_codex":0.000018206354,"about_ca_topic_score_gemma":0.000058587942,"teacher_disagreement_score":0.3292138,"about_ca_system_score_codex":0.000016436228,"about_ca_system_score_gemma":0.00007080329,"threshold_uncertainty_score":0.26862139},"labels":[],"label_agreement":null},{"id":"W3200622341","doi":"10.1212/wnl.96.15_supplement.2876","title":"Impact of the COVID-19 Pandemic on Mental Health, Physical Activity and Sleep in Children with Neuroinflammatory Disorders (2876)","year":2021,"lang":"en","type":"article","venue":"Neurology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Anxiety; Depression (economics); Medicine; Pandemic; Neuroinflammation; Psychiatry; Coronavirus disease 2019 (COVID-19); Physical therapy; Disease; Internal medicine","score_opus":0.01782780163157961,"score_gpt":0.2933875261998611,"score_spread":0.2755597245682815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3200622341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939592,0.000021464633,0.000003470909,0.00552519,0.00006081781,0.00029414616,0.000024960067,0.00002962998,0.00008113168],"genre_scores_gemma":[0.9940883,0.00007943232,9.3579416e-7,0.005788094,0.000014759369,0.0000068572363,0.0000011586462,0.000015055977,0.000005399851],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998435,0.0005804304,0.00009993977,0.00044652657,0.00015713592,0.00028094323],"domain_scores_gemma":[0.9992515,0.00026406202,0.000099276134,0.00027424228,0.0000041221615,0.00010679487],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005675728,0.00014617828,0.00020976969,0.000056347057,0.000109835615,0.000008811745,0.00016523023,0.000049109294,0.000011507934],"category_scores_gemma":[0.00019567557,0.00009900461,0.000071511175,0.00026509553,0.0003728928,0.000056759494,0.00010203656,0.000371288,0.0000020405976],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065061136,0.0004815133,0.9422174,0.00001195887,0.00000992628,0.000009280851,0.0004288427,0.0006205463,0.050713886,0.00022837869,0.00007892055,0.0045487336],"study_design_scores_gemma":[0.0013971867,0.0010156197,0.99524057,0.0000017884552,0.0000020654215,0.00018849796,0.000003626422,0.00027693345,0.0014725272,0.00020106022,0.0001173393,0.000082766644],"about_ca_topic_score_codex":0.00024158544,"about_ca_topic_score_gemma":0.0008580714,"teacher_disagreement_score":0.053023186,"about_ca_system_score_codex":0.000029012077,"about_ca_system_score_gemma":0.00021193088,"threshold_uncertainty_score":0.40372908},"labels":[],"label_agreement":null},{"id":"W3200786741","doi":"10.1101/2021.09.17.21263506","title":"Central oxidative stress and early vocational outcomes in first episode psychosis: A 7-Tesla Magnetic Resonance Spectroscopy study of glutathione","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Schulich School of Medicine and Dentistry; Canadian Institutes of Health Research; Academic Medical Organization of Southwestern Ontario; Natural Sciences and Engineering Research Council of Canada; Chrysalis","keywords":"Psychosis; Glutathione; Medicine; Confounding; Schizophrenia (object-oriented programming); Oxidative stress; Brief Psychiatric Rating Scale; Internal medicine; Cohort; Psychiatry; Psychology; Chemistry","score_opus":0.021945738113674004,"score_gpt":0.2809126387276562,"score_spread":0.2589669006139822,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3200786741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996083,0.0018088439,0.00004344398,0.000542773,0.00035445514,0.0009100916,0.000085953834,0.000036550846,0.0001348738],"genre_scores_gemma":[0.99867815,0.00047853476,0.00039487396,0.000099767996,0.000029453135,0.00017698316,0.0000051440625,0.000030115027,0.000106988264],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971185,0.00033008156,0.0005563222,0.0010433005,0.0005416247,0.00041019384],"domain_scores_gemma":[0.9986671,0.0003811676,0.0002463588,0.000554641,0.000051394774,0.00009931314],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015870674,0.00034397637,0.00058076653,0.0002137496,0.000079740326,0.00009704219,0.0005122578,0.00013827354,0.000063636726],"category_scores_gemma":[0.00059707934,0.00033465523,0.00008830094,0.00039385908,0.00022438842,0.000109144654,0.0004089505,0.00056073593,0.0000029258738],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006790001,0.0017981202,0.98636454,0.0001325402,0.00001182617,0.000046715322,0.006252397,0.000066516135,0.0046663694,0.00013771864,0.000017227796,0.00043813782],"study_design_scores_gemma":[0.0012934732,0.00027293075,0.9751187,0.0003058498,0.0000137731895,0.0000018542617,0.0010273902,0.000096982825,0.021209288,0.00036161963,0.000022365559,0.00027575152],"about_ca_topic_score_codex":0.0006410496,"about_ca_topic_score_gemma":0.0031604979,"teacher_disagreement_score":0.016542919,"about_ca_system_score_codex":0.000048203194,"about_ca_system_score_gemma":0.000059541886,"threshold_uncertainty_score":0.99991053},"labels":[],"label_agreement":null},{"id":"W3201024710","doi":"10.1016/j.tox.2021.152960","title":"Evaluating the toxicity of escalating dose of oral picolinic acid in Sprague-Dawley rats","year":2021,"lang":"en","type":"article","venue":"Toxicology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nuclear Laboratories","funders":"National Health and Medical Research Council; University of Sydney","keywords":"Histopathology; Medicine; Toxicity; Picolinic acid; Internal medicine; Pathology; Chemistry","score_opus":0.1231007853487613,"score_gpt":0.3902293463576888,"score_spread":0.2671285610089275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201024710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99648684,0.00010531122,0.000038396145,0.0007447669,0.00021582989,0.00021113141,0.0000050395524,0.000017700428,0.002174955],"genre_scores_gemma":[0.998223,0.000014116724,0.00068737124,0.0009218628,0.000021205298,0.00001371381,8.1529527e-7,0.000010154863,0.00010776222],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794096,0.0007786918,0.00047146349,0.00031015425,0.00021262921,0.00028609793],"domain_scores_gemma":[0.9984065,0.0009823515,0.00022234034,0.00030344658,0.00005078613,0.00003456322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067616097,0.00010735916,0.00029870356,0.00006804623,0.000057075347,0.000008961645,0.00028638818,0.0001085991,0.00036314456],"category_scores_gemma":[0.004412995,0.00008613165,0.00008002087,0.0005692121,0.00027592067,0.00006585021,0.00018972861,0.00023835787,0.000012050554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059755293,0.00022234069,0.0017991413,0.000023757393,0.0000034550744,0.000013457036,0.00055058283,0.0002462528,0.9824584,0.0014565018,0.00003139023,0.013134932],"study_design_scores_gemma":[0.00082598906,0.0003490468,0.017005425,0.000021445874,0.0000056163412,0.000012892792,0.00030056213,0.002193766,0.97771287,0.0014451705,0.000044598582,0.00008260892],"about_ca_topic_score_codex":0.000014129418,"about_ca_topic_score_gemma":0.00031149547,"teacher_disagreement_score":0.015206285,"about_ca_system_score_codex":0.000025033925,"about_ca_system_score_gemma":0.00020159247,"threshold_uncertainty_score":0.52830863},"labels":[],"label_agreement":null},{"id":"W3201261751","doi":"10.1101/2021.09.09.21263363","title":"Inflammation and nitro-oxidative stress in current suicidal attempts and current suicidal ideation: a systematic review and meta-analysis","year":2021,"lang":"en","type":"review","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Chulalongkorn University","keywords":"Meta-analysis; Suicidal ideation; Oxidative stress; Immune system; Neurotoxicity; Internal medicine; Confidence interval; Inflammation; Medicine; Web of science; Immunology; Poison control; Toxicity; Injury prevention","score_opus":0.12068641608069186,"score_gpt":0.3738908081564155,"score_spread":0.25320439207572365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201261751","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000961703,0.9959517,0.000049559287,0.0001551333,0.0000738659,0.0026011653,0.00015834099,0.00002928907,0.000019219804],"genre_scores_gemma":[0.0014419521,0.99762636,0.000014945954,0.000056551653,0.00003008932,0.0006561277,0.000091140435,0.000030734092,0.00005209232],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9946392,0.002014866,0.0014193237,0.0010880847,0.00051035784,0.00032816746],"domain_scores_gemma":[0.9973656,0.0009638762,0.00089183287,0.00053268997,0.000083461695,0.00016252519],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00089510897,0.0006458823,0.005457205,0.0005723168,0.000112986454,0.00021249228,0.0002697294,0.00012736642,0.000079971265],"category_scores_gemma":[0.0014935929,0.00045851187,0.0006869326,0.0016142945,0.00016338562,0.00026229417,0.00023737572,0.00048553228,0.000009788565],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000015801488,0.00008014853,0.00022791744,0.9721089,0.0043470617,0.00002347225,0.00019478069,0.0000010544167,0.0000074741083,0.0003460614,0.000018686771,0.022642855],"study_design_scores_gemma":[0.0008010653,0.000094769355,0.0003966486,0.13300635,0.84070456,0.00012936145,0.0001417859,0.0001393993,0.00019443876,0.00016523457,0.021909377,0.0023170041],"about_ca_topic_score_codex":0.000017228378,"about_ca_topic_score_gemma":0.00018406531,"teacher_disagreement_score":0.83910257,"about_ca_system_score_codex":0.00005375935,"about_ca_system_score_gemma":0.000097615986,"threshold_uncertainty_score":0.9997867},"labels":[],"label_agreement":null},{"id":"W3203542938","doi":"10.1503/jpn.210016","title":"Innate immunity receptors in depression and suicide: upregulated NOD-like receptors containing pyrin (NLRPs) and hyperactive inflammasomes in the postmortem brains of people who were depressed and died by suicide","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health","keywords":"Receptor; Innate immune system; Pyrin domain; Inflammasome; Proinflammatory cytokine; Immunology; Biology; Medicine; Inflammation; Internal medicine","score_opus":0.016868761052214316,"score_gpt":0.27004345803802016,"score_spread":0.25317469698580586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203542938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995475,0.0022539895,0.000010454831,0.0014496048,0.00054157345,0.00018091722,0.0000077811155,0.0000072747825,0.00007341965],"genre_scores_gemma":[0.99597824,0.002990349,0.000073609895,0.0008955174,0.000017604429,0.00000254846,7.2920017e-7,0.000012859708,0.000028571714],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.997701,0.00062480825,0.00057433214,0.00044148078,0.0003526897,0.0003056858],"domain_scores_gemma":[0.9984179,0.00075609353,0.0004495105,0.00019126106,0.000051485054,0.00013373692],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007241702,0.00021727571,0.000417283,0.00021896495,0.000254874,0.00013676769,0.0002868669,0.000096683085,0.0000062621225],"category_scores_gemma":[0.0010258267,0.00016405972,0.000043495264,0.000766337,0.00044912103,0.00075374177,0.0001770801,0.0005976223,6.974178e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037574512,0.0001773661,0.53236204,0.000048794755,0.0000032216876,0.000030798805,0.0028913459,0.000032424865,0.46161914,0.00010798215,0.00007734414,0.0022738068],"study_design_scores_gemma":[0.0021651902,0.00041123063,0.9257967,0.00032810483,0.0000129023865,0.00041532435,0.0044693938,0.00042840754,0.06514016,0.0004517735,0.00016272829,0.0002180988],"about_ca_topic_score_codex":0.00009659872,"about_ca_topic_score_gemma":0.0003992504,"teacher_disagreement_score":0.39647898,"about_ca_system_score_codex":0.000012553977,"about_ca_system_score_gemma":0.00012410659,"threshold_uncertainty_score":0.6690161},"labels":[],"label_agreement":null},{"id":"W3204674620","doi":"10.3389/fnsys.2021.725413","title":"Immune-Related Genetic Overlap Between Regional Gray Matter Reductions and Psychiatric Symptoms in Adolescents, and Gene-Set Validation in a Translational Model","year":2021,"lang":"en","type":"article","venue":"Frontiers in Systems Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; University of Toronto","funders":"Medical Research Council; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Psychology; Major depressive disorder; Psychiatry; Prefrontal cortex; Bipolar disorder; Schizophrenia (object-oriented programming); Neuroinflammation; Clinical psychology; Single-nucleotide polymorphism; Medicine; Internal medicine; Disease; Cognition; Gene; Genetics","score_opus":0.020102006969391167,"score_gpt":0.24242572215548144,"score_spread":0.2223237151860903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204674620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99308836,0.0014399382,0.003550937,0.0004632539,0.0009496227,0.00040485014,0.00003066509,0.000022011704,0.0000503619],"genre_scores_gemma":[0.9988815,0.00026386403,0.00045444764,0.00020853464,0.000023604278,0.000033196975,0.0000055549026,0.00001753117,0.000111730646],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9975624,0.00030663994,0.0005703329,0.0008338573,0.00036988902,0.00035686672],"domain_scores_gemma":[0.9995194,0.000034535413,0.000120868586,0.00022219043,0.000017953202,0.00008505037],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021086371,0.00018659398,0.0002628532,0.00055410666,0.0001258237,0.0001155022,0.00021394138,0.000110577064,0.0000014964402],"category_scores_gemma":[0.000075397635,0.00020327226,0.000038550912,0.0014813906,0.00028192732,0.0003712266,0.00004987664,0.00026818705,0.0000019538745],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017764505,0.00008933054,0.93419963,0.00006872236,9.912166e-7,0.000020385518,0.000488854,0.018529562,0.045987822,0.0001344203,0.00018236527,0.00028017556],"study_design_scores_gemma":[0.0013483396,0.000023547633,0.92834544,0.00014321871,0.000005227471,0.00011054954,0.00018367197,0.06720083,0.0010604274,0.0012610396,0.00005412087,0.00026357864],"about_ca_topic_score_codex":0.00004540759,"about_ca_topic_score_gemma":0.0000103701295,"teacher_disagreement_score":0.04867127,"about_ca_system_score_codex":0.000052933123,"about_ca_system_score_gemma":0.00011817131,"threshold_uncertainty_score":0.82892025},"labels":[],"label_agreement":null},{"id":"W3204782972","doi":"10.30683/1927-7229.2021.10.01","title":"Tryptophan Metabolism and Cancer Progression","year":2021,"lang":"en","type":"article","venue":"Journal of Analytical Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Science and Technology, Taiwan","keywords":"Melatonin; Kynurenine; Cancer cell; Cancer; Aryl hydrocarbon receptor; Metastasis; Biology; Cancer research; Receptor; Cell growth; Kynurenine pathway; Signal transduction; Chemistry; Tryptophan; Biochemistry; Endocrinology; Transcription factor; Amino acid","score_opus":0.038921420624793514,"score_gpt":0.3698454870265169,"score_spread":0.33092406640172334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204782972","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9692334,0.0034724625,0.00020914956,0.017717348,0.00070584874,0.000056703928,0.0000032689422,0.0000118718835,0.00858997],"genre_scores_gemma":[0.99312305,0.0019010865,0.00086795655,0.0031459578,0.00033900395,0.0000014775072,1.544488e-7,0.000009509595,0.0006118051],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988733,0.00019370804,0.00033191155,0.00016542271,0.00023813407,0.00019754935],"domain_scores_gemma":[0.9991073,0.00031357945,0.00019289716,0.00007867249,0.000112711954,0.00019485108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017647097,0.00008622315,0.00034014275,0.00008921425,0.000056746925,0.000030262505,0.00012064777,0.00009858565,0.00043285836],"category_scores_gemma":[0.00090161414,0.00006140734,0.00010704773,0.00026017166,0.00018812485,0.00012353102,0.00006280811,0.00029051825,0.000006747141],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052672735,0.0011089006,0.0011351057,0.000043564094,0.00009509985,0.0033778693,0.00045985688,0.00003062709,0.49986017,0.037733123,0.010032589,0.44559637],"study_design_scores_gemma":[0.0039768433,0.0009075195,0.015631115,0.00008000953,0.00016819428,0.0023539749,0.000371749,0.0011538944,0.28750166,0.008361369,0.67921484,0.0002788234],"about_ca_topic_score_codex":0.0000014048657,"about_ca_topic_score_gemma":0.0000051194684,"teacher_disagreement_score":0.66918224,"about_ca_system_score_codex":0.000042404376,"about_ca_system_score_gemma":0.0003420325,"threshold_uncertainty_score":0.47394955},"labels":[],"label_agreement":null},{"id":"W3204787344","doi":"10.3389/fneur.2021.721126","title":"The Relationship Between the Gut Microbiome-Immune System-Brain Axis and Major Depressive Disorder","year":2021,"lang":"en","type":"review","venue":"Frontiers in Neurology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":137,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Alberta; Ontario Brain Institute","keywords":"Major depressive disorder; Immune system; Microbiome; Gut–brain axis; Antidepressant; Mood; Gut flora; Medicine; Neuroscience; Bioinformatics; Depression (economics); Gut microbiome; Psychology; Psychiatry; Immunology; Biology; Hippocampus","score_opus":0.031575297684729595,"score_gpt":0.2869912901948815,"score_spread":0.2554159925101519,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204787344","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005013539,0.99264634,0.00022226505,0.0029175694,0.001954901,0.0013030323,0.0000884907,0.00006285824,0.00030316573],"genre_scores_gemma":[0.003246076,0.99440897,0.00004675928,0.0006761662,0.00015797165,0.0003447693,0.00004496804,0.000099258534,0.0009750513],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.994004,0.003386392,0.00081261876,0.0009680428,0.00019336223,0.00063558226],"domain_scores_gemma":[0.990642,0.007838646,0.0004814487,0.0009481725,0.000019596211,0.000070150905],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000520019,0.0004895993,0.0013025686,0.00027305345,0.0007713044,0.0001533628,0.0011981288,0.0005326011,0.000006686489],"category_scores_gemma":[0.0029216688,0.00029637953,0.00031996955,0.00093706517,0.0009839672,0.00007932605,0.00048220504,0.0014276027,0.0000226247],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007927145,0.0001115367,0.027605193,0.0075675063,0.00022732817,0.0004243262,0.000544771,0.0000065254676,0.000023959608,0.009766346,0.065780334,0.8878629],"study_design_scores_gemma":[0.0004719419,0.000051890805,0.0039540743,0.0005951471,0.000111523426,0.00017193923,0.00008743313,0.00000895189,0.0000039334363,0.0004073689,0.99383533,0.00030048774],"about_ca_topic_score_codex":0.000022344158,"about_ca_topic_score_gemma":0.000030121548,"teacher_disagreement_score":0.928055,"about_ca_system_score_codex":0.000045812783,"about_ca_system_score_gemma":0.00014922461,"threshold_uncertainty_score":0.99994886},"labels":[],"label_agreement":null},{"id":"W3206329499","doi":"","title":"Characteristics of inflammation-related depression","year":2020,"lang":"en","type":"article","venue":"Bristol Research (University of Bristol)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Depression (economics); Inflammation; Medicine; Economics; Internal medicine","score_opus":0.06991298977341044,"score_gpt":0.2853553124282268,"score_spread":0.2154423226548164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3206329499","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98839724,0.00006752649,0.00045620138,0.001925714,0.00004094863,0.00027371297,0.00005660261,0.000058815505,0.008723233],"genre_scores_gemma":[0.99901456,0.00014916931,0.00015993351,0.00003879511,0.000019123358,2.5398157e-7,0.000010478583,0.000012783251,0.0005948859],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980441,0.00031968497,0.00022360146,0.0003684239,0.0007584778,0.00028573815],"domain_scores_gemma":[0.99874777,0.0003033533,0.00022174972,0.00027639963,0.0002401037,0.0002106246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003016974,0.00010059016,0.0002664397,0.0002211824,0.00025687309,0.000015395019,0.00072320056,0.00010796123,0.0004511533],"category_scores_gemma":[0.0014968303,0.00012595768,0.00010573135,0.0009536913,0.0007343486,0.00026427908,0.0003319231,0.0003505785,0.00016292857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058459013,0.00019751413,0.00415817,0.0003420221,0.000020484207,0.00017226409,0.00459896,0.000018329842,0.93114716,0.0022064021,0.01327317,0.043280933],"study_design_scores_gemma":[0.0076189456,0.0013616796,0.25771117,0.00049807515,0.00006249486,0.000039548977,0.011650508,0.02466491,0.5708683,0.0027899395,0.12150584,0.00122857],"about_ca_topic_score_codex":0.00018588908,"about_ca_topic_score_gemma":0.000016857777,"teacher_disagreement_score":0.36027887,"about_ca_system_score_codex":0.00004873417,"about_ca_system_score_gemma":0.0001588655,"threshold_uncertainty_score":0.5136405},"labels":[],"label_agreement":null},{"id":"W3206508729","doi":"10.1016/j.psyneuen.2021.105448","title":"Depression in type 2 diabetes: A systematic review and meta-analysis of blood inflammatory markers","year":2021,"lang":"en","type":"review","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; Toronto Rehabilitation Institute; University Health Network; Canada Research Chairs","funders":"","keywords":"Depression (economics); Internal medicine; Type 2 diabetes; Confidence interval; Medicine; Meta-analysis; Strictly standardized mean difference; Inflammation; Diabetes mellitus; Systemic inflammation; Gastroenterology; Population; Brain-derived neurotrophic factor; Endocrinology; Neurotrophic factors","score_opus":0.07587271728621918,"score_gpt":0.3442010591629788,"score_spread":0.2683283418767596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3206508729","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006753619,0.9976843,5.1699703e-7,0.000081952254,0.00014830405,0.0017393243,0.00004882605,0.000039571434,0.0001896953],"genre_scores_gemma":[0.00010642104,0.99812275,0.00001557769,0.0010444873,0.0000049905907,0.00045661727,0.000016118487,0.000049940107,0.0001831045],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9937539,0.0027546585,0.0015971396,0.0011336493,0.00026022465,0.0005004165],"domain_scores_gemma":[0.99647254,0.0012454337,0.00097190106,0.0011690141,0.000047885787,0.00009320042],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017163312,0.0005638332,0.009361626,0.0010681172,0.00003626955,0.000021556387,0.0006158994,0.00012849472,0.00032538053],"category_scores_gemma":[0.0016241468,0.0004131348,0.0016921501,0.0027308397,0.0001864203,0.000065812514,0.00023598336,0.0004991481,0.000021821868],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000033729125,0.00017725138,0.000018205985,0.95805794,0.03954985,0.00027292827,0.000014261341,6.267825e-7,0.000025273057,0.000118675096,0.00022130329,0.0015403114],"study_design_scores_gemma":[0.00021725493,0.00006027891,0.000014044664,0.025467344,0.9507755,0.0001776795,0.000007301674,0.0000024282865,0.000028714485,0.000011178507,0.022792552,0.00044574644],"about_ca_topic_score_codex":0.000002469748,"about_ca_topic_score_gemma":0.000009519617,"teacher_disagreement_score":0.9325906,"about_ca_system_score_codex":0.000012294777,"about_ca_system_score_gemma":0.00007002094,"threshold_uncertainty_score":0.99983203},"labels":[],"label_agreement":null},{"id":"W3206761992","doi":"10.1038/s41380-021-01347-z","title":"Molecular characterization of depression trait and state","year":2021,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mental Health Research Canada","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Government of Canada","keywords":"Major depressive disorder; Monoaminergic; Psychology; Anterior cingulate cortex; Transcriptome; Internal medicine; Neuroscience; Medicine; Biology; Genetics; Amygdala; Gene; Cognition; Gene expression","score_opus":0.006793057413743017,"score_gpt":0.22669554394050456,"score_spread":0.21990248652676153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3206761992","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98982126,0.00035049417,0.0077535533,0.00060332054,0.00023209452,0.000104078455,0.000023589779,0.000035476423,0.0010761291],"genre_scores_gemma":[0.9974618,0.000050843864,0.00067031663,0.0017036599,0.000009544479,0.000005374018,0.000013881794,0.00002134206,0.00006324422],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999022,0.00010675678,0.00017477611,0.0003475405,0.00019140968,0.00015752298],"domain_scores_gemma":[0.99958116,0.0000116250785,0.00007938682,0.00023823071,0.000025675026,0.00006393965],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000038675098,0.000110998924,0.00012452368,0.000054856693,0.00004386557,0.000027848615,0.00009915561,0.000042071373,0.000041584488],"category_scores_gemma":[0.00006119234,0.00011381938,0.00006127414,0.00025176478,0.00005899546,0.0000723458,0.000055537526,0.00008256153,0.0000041483986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000147540295,0.00008811233,0.0008442265,0.00004401881,0.0000047772755,0.000044121894,0.000062370214,0.000010322499,0.9926599,0.0023812202,0.000014228001,0.003831948],"study_design_scores_gemma":[0.00047795128,0.000025169975,0.017172635,0.000034378907,0.0000065228187,0.00003060129,0.00002087684,0.00010540499,0.9788921,0.0027682066,0.00034235694,0.00012382907],"about_ca_topic_score_codex":0.0000016962866,"about_ca_topic_score_gemma":0.0000015815995,"teacher_disagreement_score":0.016328407,"about_ca_system_score_codex":0.0000037159177,"about_ca_system_score_gemma":0.000059213355,"threshold_uncertainty_score":0.46414194},"labels":[],"label_agreement":null},{"id":"W3207349677","doi":"10.1038/s41380-021-01327-3","title":"Anti-depressive-like behaviors of APN KO mice involve Trkb/BDNF signaling related neuroinflammatory changes","year":2021,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Tropomyosin receptor kinase B; Adiponectin; Endocrinology; Internal medicine; Neuroinflammation; Brain-derived neurotrophic factor; Medicine; Neurotrophic factors; Receptor; Diabetes mellitus; Inflammation; Insulin resistance","score_opus":0.011745709105974339,"score_gpt":0.23801692494178248,"score_spread":0.22627121583580814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3207349677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99215007,0.002266962,0.00012593048,0.0012653131,0.0015905073,0.00025399166,0.000023530634,0.00016184873,0.0021618523],"genre_scores_gemma":[0.99642473,0.000100141195,0.0006119846,0.0024814496,0.00005055705,0.000016850792,0.00001462542,0.00007989551,0.00021973593],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997511,0.00032459918,0.00043682952,0.00079769746,0.00047724412,0.0004526168],"domain_scores_gemma":[0.9987751,0.00007433979,0.00028063636,0.0006462591,0.00007566069,0.0001480065],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011412052,0.00030465834,0.0003618219,0.00018318079,0.00014917592,0.00005201272,0.00045009627,0.00016955858,0.00014466395],"category_scores_gemma":[0.00016208441,0.00033343735,0.0002473353,0.0007369267,0.00019583842,0.00011426894,0.00015858932,0.00037881927,0.000042886233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019098481,0.00025863372,0.0026048603,0.00009309454,0.000019888568,0.00037477785,0.00024549445,0.00018302839,0.9939899,0.0014326087,0.0004166015,0.00036201524],"study_design_scores_gemma":[0.0011060587,0.00008093027,0.004051732,0.00012163685,0.000056737357,0.000104072526,0.00033944778,0.000102696264,0.99197733,0.00087549514,0.00078480865,0.00039907938],"about_ca_topic_score_codex":0.0000111140835,"about_ca_topic_score_gemma":0.000022465774,"teacher_disagreement_score":0.004274696,"about_ca_system_score_codex":0.000015622745,"about_ca_system_score_gemma":0.00018967285,"threshold_uncertainty_score":0.9999118},"labels":[],"label_agreement":null},{"id":"W3208883229","doi":"","title":"The Effects of Probiotic Treatment During Puberty on LPS-Induced Immune Response in Male and Female Mice","year":2020,"lang":"en","type":"article","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Sickness behavior; Immune system; Lipopolysaccharide; Cytokine; Probiotic; Inflammation; Microbiome; Endocrinology; Immunology; Internal medicine; Physiology; Biology; Medicine; Bioinformatics","score_opus":0.02057953607414015,"score_gpt":0.24117345406731683,"score_spread":0.22059391799317668,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3208883229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968089,0.00007056177,5.87264e-7,0.0018521316,0.000043286334,0.00047905787,7.4832263e-7,0.000024857944,0.0007198601],"genre_scores_gemma":[0.9988194,0.00004782713,0.000011065491,0.00027305554,0.00000595439,0.000017940805,9.789491e-8,0.0000083721325,0.00081626663],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917746,0.00019505288,0.00013235596,0.00023751255,0.00008662183,0.00017099376],"domain_scores_gemma":[0.99883354,0.00093476946,0.000037811995,0.00014269815,0.0000040825457,0.000047128935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000071412556,0.00009927286,0.000119313954,0.00003311523,0.00008288421,0.00002906788,0.00011008105,0.000028477763,0.000010926923],"category_scores_gemma":[0.00076530606,0.000059135407,0.0000326708,0.000184801,0.000056473884,0.000056101453,0.000043411317,0.000060400496,0.000014600634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011923969,0.000096769996,0.00019379504,0.000049081762,0.0000025705021,0.000026459411,0.00085312396,0.0000033283206,0.99664944,0.000099567296,0.0000047608437,0.0008287132],"study_design_scores_gemma":[0.0013339056,0.00082936086,0.06963855,0.000025898302,0.000002027744,0.0000050490858,0.00019692571,0.00006298813,0.9277967,0.000008687431,0.000035780653,0.00006409162],"about_ca_topic_score_codex":0.000031508014,"about_ca_topic_score_gemma":0.000017915641,"teacher_disagreement_score":0.06944476,"about_ca_system_score_codex":0.000026339447,"about_ca_system_score_gemma":0.000021247415,"threshold_uncertainty_score":0.24114719},"labels":[],"label_agreement":null},{"id":"W3209224880","doi":"10.1186/s12888-021-03522-6","title":"Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms","year":2021,"lang":"en","type":"article","venue":"BMC Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Sykehuset i Vestfold; Norges Forskningsråd","keywords":"Association (psychology); Schizophrenia (object-oriented programming); Inflammation; Depressive symptoms; Clinical psychology; Plasminogen activator; Medicine; Internal medicine; Psychology; Psychiatry; Psychotherapist; Cognition","score_opus":0.037982445980251814,"score_gpt":0.24360407021962224,"score_spread":0.20562162423937042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209224880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99678475,0.00011747854,0.00043345048,0.0005846604,0.0012221893,0.00036518287,0.00006480245,0.00013808327,0.0002894082],"genre_scores_gemma":[0.9974173,0.000042018666,0.00092238246,0.00024291693,0.00022822598,0.0001988379,0.000022901311,0.00005015627,0.00087528356],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99760866,0.0002578131,0.00034725748,0.00070102897,0.0006077334,0.0004775338],"domain_scores_gemma":[0.99902743,0.00017314673,0.00029248965,0.0003385862,0.000043073098,0.00012527224],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001478697,0.00026212842,0.00024655255,0.000110941524,0.00018727101,0.0001437793,0.0002459728,0.00014402371,0.000083340405],"category_scores_gemma":[0.00037854633,0.00026004412,0.000078949786,0.00053197535,0.000032801956,0.0008709964,0.000079771235,0.00035644224,0.00006775291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037932783,0.0005366264,0.23037468,0.00013301219,0.00003926841,0.000009342823,0.000762568,0.00044239464,0.7631065,0.00067774183,0.0017511023,0.001787441],"study_design_scores_gemma":[0.004672329,0.000071769326,0.03021438,0.0001453598,0.00001371062,0.000012350605,0.00051107956,0.00017735235,0.9630178,0.00027705298,0.000465545,0.0004212363],"about_ca_topic_score_codex":0.000024082026,"about_ca_topic_score_gemma":0.00028217028,"teacher_disagreement_score":0.2001603,"about_ca_system_score_codex":0.00023992578,"about_ca_system_score_gemma":0.0003886262,"threshold_uncertainty_score":0.99998516},"labels":[],"label_agreement":null},{"id":"W3209431709","doi":"10.1136/gutjnl-2021-325985","title":"Bidirectional brain–gut axis effects influence mood and prognosis in IBD: a systematic review and meta-analysis","year":2021,"lang":"en","type":"review","venue":"Gut","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":207,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Anxiety; Depression (economics); Relative risk; Adverse effect; Internal medicine; Mood; Meta-analysis; Psychiatry; Confidence interval","score_opus":0.06706298051941112,"score_gpt":0.3411326715013973,"score_spread":0.2740696909819862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209431709","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003890168,0.99640787,0.0000044479784,0.0002774301,0.000029577379,0.0030037528,0.000055944154,0.000048273116,0.00013381631],"genre_scores_gemma":[0.00026775143,0.9959106,0.000051760482,0.0013239335,0.000009416827,0.0018434639,0.000013202353,0.000032656415,0.00054724916],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99565554,0.0016199037,0.0009207377,0.001071994,0.0004124797,0.00031935185],"domain_scores_gemma":[0.9965859,0.002267184,0.0004801146,0.0004921869,0.000045682056,0.00012893204],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00065617263,0.0005356806,0.006182035,0.0004990839,0.000097424054,0.00015893692,0.0003066808,0.00018700429,0.00008053595],"category_scores_gemma":[0.0042619384,0.00037519305,0.0012805277,0.0026684469,0.00012768291,0.00015684075,0.00019036671,0.0003423755,0.00003230216],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[4.3277478e-7,0.000065245695,0.0000055919254,0.98759604,0.008749437,0.000047610425,0.000040299088,5.9196793e-7,0.0000074489026,0.0001405267,0.00013391036,0.003212845],"study_design_scores_gemma":[0.00030536685,0.000091082744,0.000099980796,0.13294876,0.8194342,0.0004024215,0.000014053602,0.000011814395,0.000024005098,0.00007926412,0.045346864,0.0012421764],"about_ca_topic_score_codex":0.000023176843,"about_ca_topic_score_gemma":0.00004851834,"teacher_disagreement_score":0.8546473,"about_ca_system_score_codex":0.000043773038,"about_ca_system_score_gemma":0.00011256964,"threshold_uncertainty_score":0.99987},"labels":[],"label_agreement":null},{"id":"W3212558664","doi":"10.25557/2310-0435.2021.03.69-74","title":"The ratio of serum proinflammatory and anti-inflammatory cytokines in women with alcohol dependence and depressive disorders","year":2021,"lang":"ru","type":"article","venue":"Nauchno-prakticheskii zhurnal «Patogenez»","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Proinflammatory cytokine; Medicine; Alcohol dependence; Internal medicine; Depression (economics); Major depressive disorder; Context (archaeology); Psychoneuroimmunology; Psychiatry; Gastroenterology; Alcohol; Inflammation; Immunology; Immune system","score_opus":0.01101992134882853,"score_gpt":0.2359629118756802,"score_spread":0.22494299052685165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3212558664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866738,0.010203224,0.000052395117,0.0013559783,0.00024884206,0.0009546763,0.00007286064,0.000056034307,0.00038220538],"genre_scores_gemma":[0.9900101,0.008999678,0.00011957157,0.00034796292,0.000090647096,0.00012045809,0.0000018274768,0.000091356276,0.0002184032],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99458474,0.00062978535,0.0011129318,0.001325766,0.0010659223,0.0012808475],"domain_scores_gemma":[0.9966545,0.0010105964,0.0007567242,0.0009007569,0.00025798762,0.00041941705],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008484803,0.000749528,0.0008218503,0.0002871373,0.0008199701,0.00039642144,0.00072623155,0.0003697224,0.00006353177],"category_scores_gemma":[0.0010761478,0.0005902656,0.00010847883,0.0010902991,0.0016411418,0.0007167124,0.00057612464,0.00090447936,0.000008794817],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00090182136,0.00031835496,0.6845219,0.00077657803,0.00021490813,0.00088750233,0.004804292,0.00031166477,0.26793885,0.002272322,0.00005396768,0.036997784],"study_design_scores_gemma":[0.0048642163,0.00035434213,0.64103496,0.0006234459,0.000087622,0.0005864086,0.0054493365,0.0008506234,0.34288183,0.0011276511,0.0011612094,0.0009783718],"about_ca_topic_score_codex":0.000054162134,"about_ca_topic_score_gemma":0.0022045488,"teacher_disagreement_score":0.07494297,"about_ca_system_score_codex":0.00014396051,"about_ca_system_score_gemma":0.0011835537,"threshold_uncertainty_score":0.9996549},"labels":[],"label_agreement":null},{"id":"W3212964199","doi":"10.1016/j.euroneuro.2021.10.006","title":"Imaging of astrocytes in posttraumatic stress disorder: A PET study with the monoamine oxidase B radioligand [11C]SL25.1188","year":2021,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Armed Forces; University of Ottawa; McMaster University; Parkwood Institute; Lawson Health Research Institute; Dalhousie University; St Joseph's Health Care; Western University; University of Toronto; St. Michael's Hospital; Defence Research and Development Canada; Centre for Addiction and Mental Health","funders":"Canadian Institute for Military and Veteran Health Research","keywords":"Translocator protein; Astrocyte; Glial fibrillary acidic protein; Psychology; Internal medicine; Neuroscience; Endocrinology; Medicine; Microglia; Central nervous system; Immunohistochemistry; Inflammation","score_opus":0.015066656135204989,"score_gpt":0.2742222196762764,"score_spread":0.25915556354107144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3212964199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99415237,0.00023822743,0.00003929518,0.001540435,0.00031099434,0.00071309734,0.000024141538,0.00012851828,0.0028529179],"genre_scores_gemma":[0.99695814,0.00010924733,0.000041385396,0.0024641277,0.00007049046,0.000026844547,0.0000032694227,0.00011248519,0.00021399262],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99548376,0.0023468065,0.00050790503,0.0008115655,0.00031446762,0.00053549773],"domain_scores_gemma":[0.99843603,0.00058494555,0.00024201667,0.00055606436,0.00006298701,0.00011793704],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029254056,0.00034497606,0.00038499036,0.00018981348,0.00014157446,0.0000691213,0.00073540385,0.000013419821,0.00012221036],"category_scores_gemma":[0.00019969032,0.0002530333,0.00008529234,0.0009477051,0.00039326178,0.00016230853,0.00022077576,0.0004925362,0.000034028068],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006922238,0.0027706632,0.01613998,0.00005557003,0.000031746647,0.0068037026,0.0022889501,0.00067298923,0.96677256,0.000060670438,0.0006229917,0.0030879304],"study_design_scores_gemma":[0.024861638,0.0026735635,0.7656783,0.00013256258,0.00015374621,0.0015272404,0.009582396,0.0018782143,0.1878555,0.000021233718,0.0045231963,0.0011124591],"about_ca_topic_score_codex":0.000014970212,"about_ca_topic_score_gemma":0.00006909328,"teacher_disagreement_score":0.7789171,"about_ca_system_score_codex":0.00001708846,"about_ca_system_score_gemma":0.000057346213,"threshold_uncertainty_score":0.9999922},"labels":[],"label_agreement":null},{"id":"W3213132689","doi":"10.1016/j.tem.2021.10.005","title":"The menace of obesity to depression and anxiety prevalence","year":2021,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":426,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Japan Society for the Promotion of Science; Fonds de Recherche du Québec - Santé","keywords":"Insulin resistance; Anxiety; Obesity; Neuroinflammation; Mood; Leptin; Depression (economics); Adipose tissue; Medicine; Psychology; Internal medicine; Endocrinology; Inflammation; Psychiatry","score_opus":0.041764936560200194,"score_gpt":0.3392579854945033,"score_spread":0.2974930489343031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3213132689","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0026556293,0.9955291,0.0000032206765,0.00008288415,0.00030417368,0.00020289728,0.000031393847,0.00001998244,0.0011707011],"genre_scores_gemma":[0.0020119792,0.9964579,0.00007261873,0.00008724191,0.000033332835,0.00006667973,0.0000024484495,0.000015052593,0.0012527733],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978761,0.0005618976,0.00037478734,0.0006558578,0.00012993703,0.00040138722],"domain_scores_gemma":[0.99882996,0.0005080762,0.00015833609,0.00040935594,0.000013987171,0.00008029372],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001528317,0.00027718212,0.0009531206,0.0002257691,0.00014593684,0.000021405407,0.00035298013,0.00015520075,0.000030424568],"category_scores_gemma":[0.0003634873,0.00017836854,0.00012130795,0.00050680083,0.00035101362,0.000057390323,0.0004487772,0.00039928628,0.0000029086184],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005818561,0.00003731366,0.000058213038,0.0006561575,0.000009913561,0.000012021533,0.000105295265,1.6280212e-7,0.000064078406,0.0054175374,0.00013770536,0.99349576],"study_design_scores_gemma":[0.0002567369,0.000012578356,0.0025312044,0.00066608604,0.00009610509,0.00014538848,0.000022505577,7.4997547e-7,0.00070835464,0.00013368254,0.9952503,0.00017635176],"about_ca_topic_score_codex":0.000011262645,"about_ca_topic_score_gemma":0.000027478802,"teacher_disagreement_score":0.99511254,"about_ca_system_score_codex":0.000008092602,"about_ca_system_score_gemma":0.000041245537,"threshold_uncertainty_score":0.7273658},"labels":[],"label_agreement":null},{"id":"W3213320844","doi":"10.1016/j.jad.2021.11.032","title":"Metabolic function in patients with bipolar depression receiving anti-inflammatory agents: Findings from the MINDCARE study, a multicentre, randomised controlled trial","year":2021,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute for Health and Care Research","keywords":"Medicine; Bipolar disorder; Depression (economics); Internal medicine; Body mass index; Blood pressure; Waist; Metabolic syndrome; Celecoxib; Bipolar II disorder; Randomized controlled trial; Population; Physical therapy; Obesity","score_opus":0.008020158260684047,"score_gpt":0.2331553289214737,"score_spread":0.22513517066078964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3213320844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99503577,0.0008815428,0.00011478217,0.00008593556,0.00078189664,0.0030268917,0.000006892754,0.000013537531,0.00005277198],"genre_scores_gemma":[0.99948025,0.00011961152,0.000013737794,0.00021353738,0.0000748871,0.000056256853,0.0000028431111,0.000027842787,0.000011064643],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99647224,0.0016080608,0.0005604375,0.0003698577,0.00070190744,0.00028749308],"domain_scores_gemma":[0.99690974,0.0020208848,0.0005725579,0.00022182793,0.00019175277,0.00008322125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053996174,0.00025565107,0.0006438231,0.00019158442,0.00022453321,0.000105414525,0.0002640197,0.00007757574,0.00008252538],"category_scores_gemma":[0.0043629087,0.00015335354,0.00027202212,0.0005747118,0.00007607807,0.0004650991,0.000059669528,0.00045457372,0.0000037406408],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.30310515,0.0024119497,0.6764865,0.000006163528,0.00026203494,0.000030624888,0.0033473778,0.00029464284,0.0044203093,0.0000029745493,0.00010005488,0.009532195],"study_design_scores_gemma":[0.4608587,0.00036772192,0.5341808,0.000055591197,0.00011621558,6.2858106e-7,0.0025844737,0.000044644003,0.001555194,0.00002257087,0.000097515695,0.00011595248],"about_ca_topic_score_codex":0.00004900453,"about_ca_topic_score_gemma":0.000539261,"teacher_disagreement_score":0.15775353,"about_ca_system_score_codex":0.00006231466,"about_ca_system_score_gemma":0.00013682494,"threshold_uncertainty_score":0.62535757},"labels":[],"label_agreement":null},{"id":"W3213484492","doi":"","title":"The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network","year":2021,"lang":"en","type":"article","venue":"Duo Research Archive (University of Oslo)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Melancholic depression; Depression (economics); Psychiatry; Beck Depression Inventory; Cohort; Population; Psychology; Major depressive disorder; Mental health; Quality of life (healthcare); Body mass index; Medicine; Internal medicine; Clinical psychology; Melancholia; Cognition; Anxiety","score_opus":0.09357481170150068,"score_gpt":0.32168197286861555,"score_spread":0.22810716116711488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3213484492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835069,0.0013545667,0.0014099297,0.011784457,0.00003512655,0.000378692,0.0005449082,0.000026931815,0.0009584574],"genre_scores_gemma":[0.99792165,0.0006627321,0.000285751,0.0002246981,0.000025442623,0.0000012227163,0.0000751622,0.0000131709285,0.0007901483],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9945183,0.0033845908,0.0003397133,0.0005116749,0.00069970294,0.0005460303],"domain_scores_gemma":[0.9883866,0.010371187,0.00029254044,0.00047337296,0.000146795,0.0003295504],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001589189,0.00012738466,0.00035844158,0.00013999343,0.0011888826,0.00003369555,0.0005762251,0.0000979156,0.00006616765],"category_scores_gemma":[0.0050392756,0.00012903562,0.000107486165,0.0009700056,0.0013783473,0.00016005416,0.00051961676,0.0006682162,0.000018211327],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023577427,0.0007189277,0.40073135,0.0006102094,0.00046819507,0.000051082407,0.033873968,0.00027123315,0.20438972,0.0982023,0.2188009,0.03952437],"study_design_scores_gemma":[0.0033196534,0.0002907069,0.94380325,0.00010309057,0.000007420368,0.000003109666,0.0023353763,0.0005871222,0.0049505206,0.039781354,0.0045342282,0.00028417763],"about_ca_topic_score_codex":0.0008264093,"about_ca_topic_score_gemma":0.00022857984,"teacher_disagreement_score":0.54307187,"about_ca_system_score_codex":0.000043482007,"about_ca_system_score_gemma":0.00039333472,"threshold_uncertainty_score":0.9144044},"labels":[],"label_agreement":null},{"id":"W3213989677","doi":"","title":"Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function","year":2020,"lang":"en","type":"article","venue":"STM:n Hallinnonalan avoin julkaisuarkisto (Julkari)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Medicine; Translocator protein; Internal medicine; Immune system; Psychosis; Chemokine; Immune dysregulation; Immunology; Psychology; Inflammation; Psychiatry; Neuroinflammation","score_opus":0.017827134639874044,"score_gpt":0.23828275614153077,"score_spread":0.22045562150165673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3213989677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850958,0.0003088505,0.0005339984,0.0094709275,0.00029075847,0.0010609014,0.0005271628,0.00023711692,0.0024744761],"genre_scores_gemma":[0.99210113,0.00010034099,0.00018463112,0.0050623524,0.00013747849,0.00012843091,0.000056044064,0.00011783434,0.0021117416],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9953078,0.00040138126,0.001035831,0.0014238021,0.0007733035,0.0010578664],"domain_scores_gemma":[0.9982591,0.0004627082,0.00042645694,0.00043405886,0.000097102755,0.00032053038],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005240142,0.0006813182,0.0007691812,0.00035694684,0.00032382773,0.00021484934,0.00053506566,0.00028085295,0.0005915362],"category_scores_gemma":[0.00038172756,0.0006842671,0.00013633184,0.0019360938,0.00029220493,0.0005349409,0.00015412008,0.0010264787,0.00007703971],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005594035,0.0031720805,0.36767232,0.0007590361,0.00019300787,0.00051006454,0.012122371,0.005974141,0.5866651,0.0015738386,0.012499918,0.0032641094],"study_design_scores_gemma":[0.023119738,0.002079462,0.8329997,0.00038643705,0.000073082316,0.000045610464,0.0007134902,0.016070174,0.083392605,0.001887178,0.036355887,0.0028766121],"about_ca_topic_score_codex":0.0005800062,"about_ca_topic_score_gemma":0.0060825185,"teacher_disagreement_score":0.5032725,"about_ca_system_score_codex":0.00031287578,"about_ca_system_score_gemma":0.00014190777,"threshold_uncertainty_score":0.99956083},"labels":[],"label_agreement":null},{"id":"W3214762830","doi":"10.20944/preprints202111.0432.v1","title":"Oxidative Stress and Antioxidant Defenses in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis&lt;strong&gt; &lt;/strong&gt;","year":2021,"lang":"en","type":"review","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Oxidative stress; Lipid peroxidation; Glutathione; Antioxidant; Internal medicine; Homocysteine; Medicine; Meta-analysis; Strictly standardized mean difference; Endocrinology; Gastroenterology; Chemistry; Biochemistry; Enzyme","score_opus":0.1855595071568433,"score_gpt":0.3816355166924047,"score_spread":0.1960760095355614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3214762830","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0037290403,0.9894387,0.0000194478,0.00007303081,0.000041651998,0.005353206,0.0006132652,0.00007357976,0.0006580615],"genre_scores_gemma":[0.034676883,0.9626835,0.000024653282,0.00032521912,0.000014664883,0.0013890737,0.00006170201,0.00007276492,0.0007515505],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99114823,0.0032061685,0.0018803861,0.0023616476,0.00068851444,0.00071504654],"domain_scores_gemma":[0.99549896,0.0014803979,0.0013778069,0.0012035562,0.00014991315,0.0002893463],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012699078,0.0011030319,0.0084594255,0.0006377824,0.00017434657,0.0001227849,0.0006685524,0.00036713213,0.0008594325],"category_scores_gemma":[0.0024928413,0.00084038614,0.0019576494,0.0018765844,0.00041970293,0.0002858662,0.0009494731,0.0008784189,0.00017952998],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017431,0.00076870073,0.00063633925,0.95118845,0.044661235,0.0002748907,0.0006474644,0.0000026105422,0.00009927463,0.0011007548,0.000022949052,0.0005799302],"study_design_scores_gemma":[0.0011225332,0.00011792409,0.0018763015,0.19882512,0.7893719,0.00020929817,0.0005436316,0.000013980099,0.0011178148,0.00006812629,0.004334738,0.0023986553],"about_ca_topic_score_codex":0.000028445224,"about_ca_topic_score_gemma":0.000114802584,"teacher_disagreement_score":0.7523633,"about_ca_system_score_codex":0.00010847727,"about_ca_system_score_gemma":0.00026449215,"threshold_uncertainty_score":0.99940467},"labels":[],"label_agreement":null},{"id":"W3215062387","doi":"10.1016/j.euroneuro.2021.11.003","title":"Selective association of cytokine levels and kynurenine/tryptophan ratio with alterations in white matter microstructure in bipolar but not in unipolar depression","year":2021,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Kynurenine; Internal medicine; Bipolar disorder; Kynurenine pathway; Endocrinology; Fractional anisotropy; Corpus callosum; Major depressive disorder; Medicine; White matter; Cytokine; Depression (economics); Tryptophan; Psychology; Chemistry; Amygdala; Pathology; Biochemistry; Magnetic resonance imaging; Lithium (medication)","score_opus":0.011918681132542578,"score_gpt":0.25972489347915007,"score_spread":0.2478062123466075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215062387","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99711573,0.00014349578,0.00004369802,0.0010788467,0.00024531668,0.00033639406,0.00005977835,0.000034219895,0.00094249495],"genre_scores_gemma":[0.99562544,0.0000937001,0.00014065941,0.0035940004,0.000051297666,0.000011453082,0.000008499288,0.00006134847,0.00041362018],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9964155,0.0018233692,0.0004822043,0.0007089919,0.00018985292,0.00038007204],"domain_scores_gemma":[0.99919325,0.00024919462,0.00022492984,0.0001970122,0.000066711174,0.00006892392],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024094642,0.0002371724,0.00030789865,0.00040661485,0.000056188648,0.00004323012,0.00019486474,0.00008150822,0.00012141666],"category_scores_gemma":[0.00022046514,0.00023116592,0.000028730514,0.0011086437,0.00009590225,0.0002337153,0.00009978021,0.0006197224,0.000014209421],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032132867,0.00015166045,0.16799273,0.000022971331,0.0000045565157,0.00030849775,0.00081948657,0.00046400985,0.8293721,0.00001689039,0.00024497433,0.00028078773],"study_design_scores_gemma":[0.0034952313,0.00008218597,0.72570544,0.000030570598,0.0000060593115,0.000049547223,0.000038681406,0.0001482439,0.26978475,0.000017622277,0.00048112642,0.00016053977],"about_ca_topic_score_codex":0.000016700078,"about_ca_topic_score_gemma":0.00028099175,"teacher_disagreement_score":0.55958736,"about_ca_system_score_codex":0.00007366907,"about_ca_system_score_gemma":0.00006907806,"threshold_uncertainty_score":0.94266725},"labels":[],"label_agreement":null},{"id":"W3215147148","doi":"10.1007/s12264-021-00802-9","title":"Do Systemic Infections Contribute to the Pathogenesis of Dementia?","year":2021,"lang":"en","type":"article","venue":"Neuroscience Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pain medicine; Human physiology; Pathogenesis; Dementia; Neurology; Medicine; Anesthesiology; Intensive care medicine; Psychiatry; Immunology; Internal medicine; Disease","score_opus":0.02112035015435117,"score_gpt":0.25158102983792596,"score_spread":0.23046067968357478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215147148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97876364,0.00029876977,0.0038601372,0.012639635,0.0015169381,0.00049648527,0.00008350299,0.00010638473,0.0022344927],"genre_scores_gemma":[0.99226004,0.000103005485,0.000049515376,0.006911886,0.00003754314,0.000041127612,4.2837274e-7,0.000011359156,0.0005850893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813473,0.0002790504,0.00026009497,0.00054413825,0.00043791323,0.00034407058],"domain_scores_gemma":[0.9988951,0.00032400968,0.000095985866,0.00049112464,0.00008510678,0.00010864786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002705645,0.00012441447,0.00015108925,0.00007297284,0.00036651856,0.00011288317,0.0005095357,0.000034499186,0.0002069456],"category_scores_gemma":[0.0035960807,0.00009415668,0.000094118914,0.0010816797,0.00018867494,0.000042998156,0.00022376669,0.00010675565,0.00020966842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004921196,0.000097157106,0.00062353746,0.000011040105,7.929263e-7,0.000022597113,0.00009493034,0.00043713953,0.9918806,0.0020392179,0.0038274361,0.00096065167],"study_design_scores_gemma":[0.00041757943,0.00015367284,0.017598893,0.000048771002,0.000015727788,0.00025842572,0.00023692095,0.00010531389,0.6404426,0.00008937527,0.34040368,0.00022900802],"about_ca_topic_score_codex":0.00000959308,"about_ca_topic_score_gemma":0.000007335109,"teacher_disagreement_score":0.35143796,"about_ca_system_score_codex":0.000014204454,"about_ca_system_score_gemma":0.00009380349,"threshold_uncertainty_score":0.43051043},"labels":[],"label_agreement":null},{"id":"W3215865221","doi":"10.14309/01.ajg.0000798608.48127.a2","title":"P002 Psychiatric Comorbidity and Suicide in Childhood Onset Immune-Mediated Diseases —A Systematic Review and Meta-Analysis","year":2021,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Comorbidity; Psychiatric comorbidity; Meta-analysis; Psychiatry; Internal medicine","score_opus":0.021202281855402832,"score_gpt":0.27470950890562984,"score_spread":0.253507227050227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215865221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9553867,0.035841413,0.000058188216,0.00844657,0.000025448839,0.00018782096,0.000043824104,0.000005969453,0.0000040481777],"genre_scores_gemma":[0.9792633,0.009408196,0.00006199422,0.011233576,0.0000075130865,0.000008250732,0.0000017034954,0.00000818571,0.0000072864304],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9966895,0.001989709,0.0006798904,0.00021207979,0.00018499003,0.00024383851],"domain_scores_gemma":[0.99811286,0.00052841974,0.0009110374,0.0002922077,0.000045868466,0.000109613306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046741345,0.00015983474,0.0020002783,0.00021927003,0.000061657374,0.000027026357,0.00028720652,0.0000124208445,0.000057264835],"category_scores_gemma":[0.00077300577,0.0000945077,0.00042758547,0.00078640896,0.0004183271,0.00007154323,0.00009113475,0.0002454786,0.0000019955653],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009152519,0.009271344,0.6846626,0.06220236,0.21012636,0.0043325475,0.0071530216,0.0006127537,0.008659689,0.00037778946,0.002948723,0.0005003208],"study_design_scores_gemma":[0.0019834137,0.003491552,0.6799037,0.00039456837,0.30668744,0.0052756383,0.0014077983,0.0000568725,0.00010807549,0.00041231018,0.000006220882,0.00027242737],"about_ca_topic_score_codex":0.000018731887,"about_ca_topic_score_gemma":0.000058302936,"teacher_disagreement_score":0.09656109,"about_ca_system_score_codex":0.000012336064,"about_ca_system_score_gemma":0.000033352117,"threshold_uncertainty_score":0.3853912},"labels":[],"label_agreement":null},{"id":"W323543006","doi":"","title":"Postreceptor pathways for signal transduction in depression and bipolar disorder.","year":2001,"lang":"en","type":"article","venue":"PubMed","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Signal transduction; Cyclic adenosine monophosphate; Bipolar disorder; Neuroscience; CREB; Depression (economics); Pathophysiology; Treatment of bipolar disorder; Mood stabilizer; Psychology; Medicine; Psychiatry; Endocrinology; Internal medicine; Biology; Cell biology; Receptor; Mania; Genetics; Cognition; Transcription factor","score_opus":0.02763342767442755,"score_gpt":0.22126495911631502,"score_spread":0.19363153144188747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W323543006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99710596,0.0006132034,0.0006547519,0.00030054,0.00013990047,0.0007832532,0.000015759104,0.000058255362,0.00032840224],"genre_scores_gemma":[0.9986368,0.0002819844,0.000043903146,0.00018831706,0.00004842784,0.00066263904,0.0000034600785,0.000013107958,0.00012137463],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99915045,0.0000414234,0.00011926877,0.0002946203,0.000097478754,0.0002967832],"domain_scores_gemma":[0.99971473,0.000100157544,0.000028421808,0.000076977056,0.0000067321866,0.00007296821],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103683,0.00009029838,0.00008761137,0.000090122965,0.000081272505,0.000029890536,0.00008381162,0.000054404387,0.00004387954],"category_scores_gemma":[0.00012922302,0.00008145968,0.000033382097,0.00018975987,0.000052885334,0.00017684889,0.000013451869,0.000069175745,0.0000022912507],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015375632,0.0001221741,0.014389892,0.000015403402,0.0000010535002,0.0000025652328,0.00023528661,0.000012720061,0.062327746,0.00018025884,0.000073490955,0.92248565],"study_design_scores_gemma":[0.0036148003,0.00008600436,0.5869787,0.000014321659,0.0000069618877,0.00003097904,0.00032003337,0.0006961803,0.31723422,0.0023982027,0.08822241,0.00039719907],"about_ca_topic_score_codex":0.000017267375,"about_ca_topic_score_gemma":0.000054076914,"teacher_disagreement_score":0.92208844,"about_ca_system_score_codex":0.000014051412,"about_ca_system_score_gemma":0.00000698808,"threshold_uncertainty_score":0.33218294},"labels":[],"label_agreement":null},{"id":"W4200070248","doi":"10.1016/j.euroneuro.2021.10.281","title":"P.0297 Selective downregulation of cortical mglu2 receptors in the maternal immune activation model of schizophrenia: association with histone posttranslational modifications","year":2021,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Agencia Estatal de Investigación; Universitat Politècnica de València; European Regional Development Fund; Euskal Herriko Unibertsitatea; Ministerio de Ciencia, Innovación y Universidades","keywords":"Antagonism; Ternary operation; Chemistry; Toxicity; Component (thermodynamics); Quenching (fluorescence); Additive function; Ionic liquid; Health hazard; Receptor; Organic chemistry; Biochemistry; Computer science; Fluorescence; Thermodynamics; Catalysis","score_opus":0.025747873599459768,"score_gpt":0.2868635386149517,"score_spread":0.2611156650154919,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200070248","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929228,0.00002114888,0.0014175584,0.0014483338,0.00015387306,0.00029563493,0.000022125441,0.000043403223,0.003675121],"genre_scores_gemma":[0.99884146,0.000040060895,0.00038049265,0.00048214497,0.00004294082,0.000013937641,0.000015081305,0.00003576057,0.00014813809],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99699485,0.0015144201,0.0005047834,0.00037274286,0.00040299064,0.0002101958],"domain_scores_gemma":[0.9986723,0.00050724595,0.00039175845,0.00020378652,0.00019093227,0.00003396015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003613029,0.00014671577,0.00019731621,0.00016236199,0.000093015035,0.000015975564,0.00026565173,0.000050920975,0.000063239575],"category_scores_gemma":[0.0002966391,0.00012409054,0.00006766779,0.0007836401,0.0001562289,0.0001769521,0.000025953395,0.00037828204,0.000009188529],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007077798,0.00038347396,0.0005961588,0.000012694491,0.00001419764,0.000007639761,0.00074265146,0.013407532,0.9813659,0.0018458976,0.00019359845,0.00072242704],"study_design_scores_gemma":[0.0032492143,0.0001834727,0.5437677,0.000021232972,0.00003503699,0.000024302257,0.0000669498,0.01147139,0.44056362,0.00033371733,0.00011241161,0.00017095308],"about_ca_topic_score_codex":0.0000062740028,"about_ca_topic_score_gemma":0.00000437747,"teacher_disagreement_score":0.5431715,"about_ca_system_score_codex":0.00006615985,"about_ca_system_score_gemma":0.000111655616,"threshold_uncertainty_score":0.5060265},"labels":[],"label_agreement":null},{"id":"W4200075276","doi":"10.4103/1673-5374.330618","title":"Efficacy of Lycium barbarum polysaccharide in adolescents with subthreshold depression: interim analysis of a randomized controlled study","year":2021,"lang":"en","type":"article","venue":"Neural Regeneration Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Medicine; Placebo; Randomized controlled trial; Depression (economics); Beck Depression Inventory; Hamd; Psychiatry; Pittsburgh Sleep Quality Index; Internal medicine; Major depressive disorder; Anxiety; Physical therapy; Insomnia","score_opus":0.06983961486487814,"score_gpt":0.3720140050888404,"score_spread":0.3021743902239623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200075276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974704,0.0002435105,0.000094302224,0.00030913064,0.000059208098,0.0016419779,0.0000048154607,0.000014133724,0.00016252519],"genre_scores_gemma":[0.9994455,0.000038304857,0.000015731384,0.00007609251,0.000020141899,0.00014900806,0.0000038678377,0.000013648735,0.0002376943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99418455,0.0029464809,0.0007816742,0.0005448803,0.0012206923,0.00032170504],"domain_scores_gemma":[0.99803793,0.00083415426,0.00020513339,0.00047716682,0.0003579221,0.000087691114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001535351,0.00015108513,0.0012244242,0.0009751556,0.000088015644,0.0000683122,0.00030818902,0.0000595654,0.00010344427],"category_scores_gemma":[0.0041318545,0.00010355896,0.0002957959,0.003113774,0.0002610017,0.00012845993,0.00014484099,0.00030861364,0.0000018998945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.10134714,0.0014039448,0.02103583,0.000026311543,0.0001375326,0.00006485026,0.0004827619,0.0027199977,0.8722585,0.00014892341,0.000017860684,0.00035636427],"study_design_scores_gemma":[0.20855318,0.00021298171,0.025788017,0.00008910475,0.00012575989,0.000001957126,0.00044795914,0.030321142,0.7343371,0.000014982233,9.666488e-7,0.000106851956],"about_ca_topic_score_codex":0.00012765758,"about_ca_topic_score_gemma":0.00072155276,"teacher_disagreement_score":0.13792138,"about_ca_system_score_codex":0.000030695173,"about_ca_system_score_gemma":0.0001621429,"threshold_uncertainty_score":0.49465144},"labels":[],"label_agreement":null},{"id":"W4200153626","doi":"10.1101/2021.12.16.21267905","title":"The tryptophan catabolite or kynurenine pathway in schizophrenia: meta-analysis reveals dissociations between central, serum and plasma compartments","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Chulalongkorn University","keywords":"Kynurenine; Kynurenine pathway; Kynurenic acid; Xanthurenic acid; Quinolinic acid; Tryptophan; Schizophrenia (object-oriented programming); Internal medicine; Chemistry; Endocrinology; Medicine; Biochemistry; Psychiatry; Amino acid","score_opus":0.08734190487181599,"score_gpt":0.3097213411583042,"score_spread":0.2223794362864882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200153626","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99307483,0.0017305783,0.00005229832,0.0025268316,0.00031840077,0.000711222,0.0013581542,0.00008118679,0.00014647901],"genre_scores_gemma":[0.9971837,0.0006795198,0.00020207238,0.00024307916,0.00011208165,0.00014183525,0.00018907886,0.000041946594,0.0012067207],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99527174,0.0010999306,0.0009103052,0.0012580485,0.0006801743,0.0007798064],"domain_scores_gemma":[0.99677336,0.0013476533,0.0005144466,0.0010431792,0.000061825674,0.00025954476],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005732955,0.0005497302,0.0016710695,0.00031221364,0.000472752,0.0005323904,0.00088140724,0.00027432712,0.0002030502],"category_scores_gemma":[0.001105943,0.00036023563,0.0008687217,0.0015093947,0.00024686204,0.00015004647,0.000790457,0.0008729093,0.0000120188],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084198115,0.0022497724,0.8142368,0.00076889043,0.12025491,0.00083549286,0.013138458,0.0033062233,0.024507893,0.005643886,0.0019879334,0.01222773],"study_design_scores_gemma":[0.0016078764,0.00003879016,0.9539516,0.000034383287,0.01667941,0.0000039993165,0.0003613619,0.00053867156,0.02209338,0.0014702735,0.0023313437,0.0008889071],"about_ca_topic_score_codex":0.00008094342,"about_ca_topic_score_gemma":0.0023454847,"teacher_disagreement_score":0.13971478,"about_ca_system_score_codex":0.00007974292,"about_ca_system_score_gemma":0.00019511905,"threshold_uncertainty_score":0.99988496},"labels":[],"label_agreement":null},{"id":"W4200222061","doi":"10.1016/j.euroneuro.2021.12.003","title":"A review and meta-analysis of gene expression profiles in suicide","year":2021,"lang":"en","type":"review","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health; Ottawa Hospital; Dalhousie University; University of Ottawa","funders":"","keywords":"Dorsolateral prefrontal cortex; Gene expression; Prefrontal cortex; Gene; Subfamily; Biology; Medicine; Neuroscience; Bioinformatics; Genetics; Cognition","score_opus":0.14385822138907645,"score_gpt":0.4011974820411666,"score_spread":0.2573392606520902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200222061","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000050965173,0.9965986,0.000004272422,0.00013645437,0.00016932408,0.0011944055,0.00017230566,0.000081452825,0.0015922207],"genre_scores_gemma":[0.00004000889,0.99305606,0.000100330304,0.0061081853,0.00003260792,0.00011550225,0.000035639878,0.00015546962,0.00035620143],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9892048,0.007275964,0.0013928021,0.0014684306,0.00022929141,0.00042867396],"domain_scores_gemma":[0.9973994,0.000811057,0.0008687509,0.00072399236,0.000044849858,0.00015195567],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00059393316,0.0006398692,0.005661706,0.00091272773,0.000044839806,0.000026902055,0.000783618,0.000105189414,0.001150239],"category_scores_gemma":[0.0004737226,0.00048629436,0.0018958293,0.0029735914,0.00024046376,0.000078751975,0.00034024494,0.0006823749,0.00004066199],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011874483,0.0030255364,0.0000082774895,0.17152543,0.09962346,0.009709213,0.00043689884,0.00004808854,0.20272973,0.00031859553,0.051064797,0.46139124],"study_design_scores_gemma":[0.0002957111,0.000050462615,0.000019330466,0.000715915,0.27637354,0.00007928521,0.0000022639279,0.0000014495829,0.00038330109,0.0000014742287,0.7216681,0.00040917014],"about_ca_topic_score_codex":0.000002283125,"about_ca_topic_score_gemma":0.0000015661,"teacher_disagreement_score":0.67060333,"about_ca_system_score_codex":0.000016648946,"about_ca_system_score_gemma":0.000074922566,"threshold_uncertainty_score":0.99976283},"labels":[],"label_agreement":null},{"id":"W4200401716","doi":"10.20944/preprints202112.0301.v1","title":"The Tryptophan Catabolite or Kynurenine Pathway in Schizophrenia: Meta-Analysis Reveals Dissociations Between Central, Serum and Plasma Compartments","year":2021,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Chulalongkorn University","keywords":"Kynurenine; Kynurenine pathway; Kynurenic acid; Xanthurenic acid; Quinolinic acid; Tryptophan; Internal medicine; Schizophrenia (object-oriented programming); Endocrinology; Chemistry; Medicine; Biochemistry; Psychiatry; Amino acid","score_opus":0.20746221513050267,"score_gpt":0.36082132251860427,"score_spread":0.1533591073881016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200401716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99415874,0.00073996856,0.000029185458,0.0020236825,0.00030234293,0.0011008193,0.0010046479,0.00012736295,0.0005132732],"genre_scores_gemma":[0.9961776,0.0007253162,0.00011191393,0.00023321465,0.00010728132,0.00036213474,0.00019894379,0.00005186026,0.002031696],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9939592,0.0012534779,0.0011695323,0.0019352841,0.00076719344,0.0009153161],"domain_scores_gemma":[0.9958866,0.00121689,0.00070655276,0.0017737752,0.00009392115,0.00032223694],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008197246,0.00067003974,0.0018500963,0.00034378638,0.0005417276,0.00029697674,0.0012320724,0.00036878025,0.0007108121],"category_scores_gemma":[0.0016564059,0.00048664017,0.0010526686,0.0013713484,0.00029968005,0.00021538248,0.002240185,0.0012463903,0.00008502301],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003075395,0.000760578,0.9461664,0.00021916852,0.03085564,0.0001242605,0.004134752,0.0014952599,0.013174742,0.0012830615,0.00010747773,0.0013711196],"study_design_scores_gemma":[0.0010014325,0.000012423976,0.93996704,0.000026734991,0.008125328,0.0000029493012,0.0002538299,0.00017375802,0.04757297,0.0011363907,0.0011305128,0.0005966297],"about_ca_topic_score_codex":0.00019382816,"about_ca_topic_score_gemma":0.0015380917,"teacher_disagreement_score":0.034398228,"about_ca_system_score_codex":0.00015337122,"about_ca_system_score_gemma":0.0002765285,"threshold_uncertainty_score":0.99975854},"labels":[],"label_agreement":null},{"id":"W4200439360","doi":"10.1016/j.euroneuro.2021.10.656","title":"P.0696 Nuclei RNAseq reveals transcriptional alterations of prefrontal cortex astrocytes in a subpopulation of suicide completers.","year":2021,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"Boehringer Ingelheim","keywords":"Pannexin; Biology; Extracellular; Cell biology; Transmembrane protein; Transmembrane domain; Amino acid; Biophysics; Biochemistry; Intracellular; Gap junction; Connexin; Receptor","score_opus":0.04272834134460157,"score_gpt":0.3037514828861359,"score_spread":0.26102314154153433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200439360","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99467915,0.00010995493,0.00025543448,0.00028400164,0.00058122975,0.00026511808,0.00011313816,0.00006218778,0.0036497696],"genre_scores_gemma":[0.997797,0.00007624301,0.00031651725,0.0014932532,0.000068502566,0.0000066320317,0.000033548833,0.00005282022,0.00015548297],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9970434,0.0012395264,0.0006995975,0.00049960386,0.0002334327,0.00028449047],"domain_scores_gemma":[0.9991334,0.0002271759,0.00025049123,0.00022889311,0.0000766145,0.00008343857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000160041,0.00018153562,0.00030447607,0.00020134456,0.00005410737,0.00001539363,0.00028659773,0.00003364401,0.0005099273],"category_scores_gemma":[0.00016213104,0.0002023865,0.000117689764,0.00044915627,0.00022894172,0.0001554845,0.000058209578,0.0002377365,0.000031772233],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002618697,0.00044211457,0.0026168884,0.00003590713,0.000008314726,0.00017919966,0.00028379465,0.00029799138,0.9938466,0.0009255819,0.0004919692,0.0006098031],"study_design_scores_gemma":[0.0031503346,0.00024470515,0.86560994,0.000033503857,0.000016422222,0.00008081214,0.000054651697,0.00048612955,0.12865925,0.00011010482,0.0013740973,0.00018006962],"about_ca_topic_score_codex":0.000010920504,"about_ca_topic_score_gemma":0.00003137931,"teacher_disagreement_score":0.86518735,"about_ca_system_score_codex":0.000021099964,"about_ca_system_score_gemma":0.000046756737,"threshold_uncertainty_score":0.8253082},"labels":[],"label_agreement":null},{"id":"W4200587029","doi":"10.1016/j.jpsychires.2021.12.051","title":"Serum amyloid P component level is associated with clinical response to escitalopram treatment in patients with major depressive disorder","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Escitalopram; Major depressive disorder; Depression (economics); Antidepressant; Internal medicine; Hamd; Hamilton Rating Scale for Depression; Psychology; Medicine; Psychiatry; Hippocampus; Significant difference","score_opus":0.0828583960017225,"score_gpt":0.3848280262606391,"score_spread":0.3019696302589166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200587029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99171734,0.00016253804,0.0000784757,0.0070065963,0.00021682766,0.0005456345,0.00006496583,0.000009231697,0.00019837354],"genre_scores_gemma":[0.9977229,0.000084679625,0.0007627138,0.0005016333,0.00007019051,0.000014861203,0.00000242026,0.000035307123,0.00080524525],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99408615,0.0021600025,0.0007548188,0.00052529096,0.0018194213,0.00065434584],"domain_scores_gemma":[0.99650335,0.0017209516,0.00032696998,0.00038754,0.00067309616,0.00038810066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015956261,0.00021668733,0.00047115877,0.0007253402,0.00023404612,0.00013802886,0.00046305987,0.000115534596,0.00011610227],"category_scores_gemma":[0.0022080368,0.00014067112,0.00014840151,0.002552454,0.00017132884,0.00017687831,0.00011322914,0.0007872919,0.000033040338],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016724383,0.006127497,0.96528566,0.000013270745,0.000107267515,0.0006134897,0.000717398,0.00010602331,0.00081281614,0.000026641943,0.0037842637,0.0056812945],"study_design_scores_gemma":[0.013798875,0.005777203,0.97703207,0.0000926316,0.000018373457,0.00002327872,0.00032092058,0.00001892508,0.0012779279,0.00013721979,0.0013120555,0.0001905274],"about_ca_topic_score_codex":0.000040599076,"about_ca_topic_score_gemma":0.00031949015,"teacher_disagreement_score":0.011746409,"about_ca_system_score_codex":0.00029104826,"about_ca_system_score_gemma":0.0010310849,"threshold_uncertainty_score":0.5736402},"labels":[],"label_agreement":null},{"id":"W4205099026","doi":"10.1080/08039488.2021.2023217","title":"Unraveiling the correlation among neurodevelopmental and inflammatory biomarkers in patients with chronic schizophrenia","year":2022,"lang":"en","type":"article","venue":"Nordic Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Centros de Pesquisa, Inovação e Difusão, Fundação Amazônia Paraense de Amparo à Pesquisa; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Schizophrenia (object-oriented programming); Biomarker; Neurotensin; Brain-derived neurotrophic factor; Neurotrophic factors; Medicine; Internal medicine; Endocrinology; Psychology; Neuroscience; Neuropeptide; Biology; Psychiatry; Receptor","score_opus":0.004939701063033082,"score_gpt":0.19536077572164576,"score_spread":0.1904210746586127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205099026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998113,0.00024502014,0.000038024704,0.00033094396,0.0009550594,0.00016453279,0.0000024061242,0.000007750599,0.00014331016],"genre_scores_gemma":[0.99954003,0.0000113585065,0.0001301057,0.00024356917,0.000048720452,0.000003443639,8.1797737e-7,0.000013714674,0.000008234688],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987997,0.00016715974,0.00030886434,0.00015441621,0.0004054521,0.00016442852],"domain_scores_gemma":[0.9994583,0.00006568065,0.00031249598,0.0000966502,0.000016370728,0.000050474566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026146576,0.00010327113,0.00010576464,0.00019420525,0.00028063965,0.000030289197,0.00021923805,0.000021854972,0.00004752374],"category_scores_gemma":[0.000040534436,0.00007338097,0.000036733312,0.0003540211,0.0001288288,0.00020001957,0.00007205042,0.00045693884,9.907202e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045601363,0.00008456559,0.99427736,0.000009726463,0.000013969411,0.0000069796715,0.00026435923,0.000942936,0.00036618748,0.00014819721,0.00014937723,0.0032803272],"study_design_scores_gemma":[0.003078586,0.00028566012,0.99544203,0.0000334506,0.0000069293765,0.000035728197,0.00033335632,0.00024425265,0.00003249265,0.0002729871,0.00013824004,0.00009627276],"about_ca_topic_score_codex":0.0000057869725,"about_ca_topic_score_gemma":0.00006504375,"teacher_disagreement_score":0.0031840545,"about_ca_system_score_codex":0.00008242064,"about_ca_system_score_gemma":0.0002855853,"threshold_uncertainty_score":0.29923892},"labels":[],"label_agreement":null},{"id":"W4205130373","doi":"10.1038/s41467-021-27604-x","title":"Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":273,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire en santé mentale de Montréal; McGill University; Douglas Mental Health University Institute; Institut Universitaire en Santé Mentale de Québec; Université Laval","funders":"National Institute of Mental Health; European Regional Development Fund; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Irish Research Council; National Science Foundation; Science Foundation Ireland; Canada First Research Excellence Fund; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Transcriptome; Prefrontal cortex; Depression (economics); Chronic stress; Social stress; Social defeat; Blood–brain barrier; Gene expression profiling; Human brain","score_opus":0.02301829254783367,"score_gpt":0.3091122634821164,"score_spread":0.28609397093428274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205130373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97569585,0.018858762,9.462515e-7,0.0047271587,0.000024614299,0.00030795217,0.00003949846,0.000033093427,0.00031214257],"genre_scores_gemma":[0.9972924,0.0016542276,0.00014096967,0.00065762555,0.0000034364787,0.00007003026,0.00001182982,0.000012294763,0.00015717564],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983631,0.0007990689,0.00015379456,0.00035413078,0.00015861669,0.00017129147],"domain_scores_gemma":[0.9982143,0.0009983121,0.000060726205,0.00065655663,0.000012348749,0.000057769295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034732706,0.00011168516,0.00013178402,0.00025863317,0.0006115413,0.000045137745,0.0005230355,0.00012277186,0.000015959304],"category_scores_gemma":[0.0009072218,0.00011761266,0.000010647608,0.00051932817,0.0003300618,0.000108328124,0.0009038588,0.0008816227,2.7583692e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007280335,0.0004901931,0.10996737,0.000059778802,0.0000098496175,0.00003898151,0.009516493,0.00007084348,0.86536,0.009262153,0.00026634897,0.0048851655],"study_design_scores_gemma":[0.0040578647,0.00027214468,0.8849361,0.00023236457,0.00002902825,0.00009524002,0.010152464,0.0011338996,0.078337155,0.0034697624,0.016555095,0.000728898],"about_ca_topic_score_codex":0.00010784791,"about_ca_topic_score_gemma":0.0042054798,"teacher_disagreement_score":0.7870229,"about_ca_system_score_codex":0.000020585057,"about_ca_system_score_gemma":0.000024197703,"threshold_uncertainty_score":0.4796105},"labels":[],"label_agreement":null},{"id":"W4205199569","doi":"10.3389/fimmu.2021.803633","title":"Characteristics of Dysregulated Proinflammatory Cytokines and Cognitive Dysfunction in Late-Life Depression and Amnestic Mild Cognitive Impairment","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Montreal Cognitive Assessment; Proinflammatory cytokine; Medicine; Internal medicine; Depression (economics); Neuropsychology; Biomarker; Cognition; Oncology; Cognitive impairment; Inflammation; Disease; Psychiatry","score_opus":0.009387455971996915,"score_gpt":0.21952675784891298,"score_spread":0.21013930187691607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205199569","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99736524,0.0012308275,0.00016203611,0.000066810004,0.00051331497,0.00053601456,0.00004909353,0.000026586848,0.000050073875],"genre_scores_gemma":[0.9993144,0.00028958314,0.00004409671,0.00015482685,0.0000075553494,0.000108833345,0.000020190171,0.000015609574,0.00004487828],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99859625,0.0003459474,0.0003178943,0.00037445244,0.00011978137,0.0002456529],"domain_scores_gemma":[0.9994888,0.00019621896,0.00017226918,0.00008415801,0.000024357569,0.000034251425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001551755,0.00014838627,0.0002999494,0.0003793881,0.0001109989,0.000009487302,0.00008664356,0.000084748426,0.000027116988],"category_scores_gemma":[0.00045763655,0.00015558166,0.000020315698,0.00031031584,0.00041706217,0.00010263576,0.00020241851,0.00028708286,8.1806485e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0060782423,0.0006595764,0.8622708,0.00015765223,0.00006409447,0.00015253985,0.0050675077,0.00004535264,0.092923865,0.00009987561,0.00016277873,0.032317717],"study_design_scores_gemma":[0.0039919317,0.00036587933,0.9792251,0.000104478866,0.000017742143,0.000022830007,0.0023261942,0.0013197653,0.0118983975,0.0005113111,0.000038553007,0.00017782208],"about_ca_topic_score_codex":0.000027470773,"about_ca_topic_score_gemma":0.0000072702846,"teacher_disagreement_score":0.1169543,"about_ca_system_score_codex":0.000047361125,"about_ca_system_score_gemma":0.000057896563,"threshold_uncertainty_score":0.6344436},"labels":[],"label_agreement":null},{"id":"W4205199917","doi":"10.22215/etd/2021-14775","title":"Peripheral biomarkers in Repeated Ketamine Infusions Trial","year":2021,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Ketamine; Antidepressant; Medicine; Endocrine system; Peripheral; Depression (economics); Major depressive disorder; Clinical trial; Glucocorticoid; Immune system; Internal medicine; Anesthesia; Immunology; Hormone","score_opus":0.025269422099386877,"score_gpt":0.29165713229584944,"score_spread":0.26638771019646257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205199917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86519897,0.000101632766,0.0000017457072,0.00012873454,0.0015521995,0.00054240116,0.00001106352,0.00010874806,0.1323545],"genre_scores_gemma":[0.8492499,0.00031195962,0.00011248084,0.00082126085,0.00014040596,0.00013267371,0.0010148028,0.00007355222,0.14814296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99809474,0.00017756668,0.00043276366,0.00067227945,0.00031390478,0.00030877508],"domain_scores_gemma":[0.99928933,0.00014994795,0.00012225086,0.0003272891,0.000033791577,0.000077398996],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000096638745,0.00026634312,0.00032837671,0.00027637524,0.00008773857,0.00008864599,0.00025935253,0.00030461242,0.0035294876],"category_scores_gemma":[0.0012179998,0.00024601273,0.00017133729,0.00087072316,0.000042620875,0.00009278901,0.00003283751,0.00030981857,0.000040502455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022064628,0.0010341423,0.00010664073,0.0001540818,0.000054358454,0.0004906231,0.002199218,0.000010482057,0.9404078,0.0013780294,0.010461035,0.021638952],"study_design_scores_gemma":[0.19863163,0.0012579089,0.03395916,0.00095106213,0.000098269666,0.000045223464,0.022758912,0.0012136095,0.69214624,0.0010366687,0.043726854,0.004174488],"about_ca_topic_score_codex":0.00020106371,"about_ca_topic_score_gemma":0.003516215,"teacher_disagreement_score":0.24826159,"about_ca_system_score_codex":0.000054681015,"about_ca_system_score_gemma":0.00023363913,"threshold_uncertainty_score":0.9999992},"labels":[],"label_agreement":null},{"id":"W4205491359","doi":"10.2139/ssrn.4011647","title":"Differential Effects of Lipopolysaccharide on Cognition, Corticosterone and Cytokines in Socially-Housed vs Isolated Male Rats","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"","keywords":"Lipopolysaccharide; Corticosterone; Cognition; Endocrinology; Psychology; Internal medicine; Developmental psychology; Medicine; Physiology; Neuroscience; Hormone","score_opus":0.008004474536486486,"score_gpt":0.22487283553745332,"score_spread":0.21686836100096685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205491359","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99852693,0.00019013064,0.00025737344,0.00042878345,0.0002495,0.00024344373,0.0000071434956,0.000026701427,0.000069974274],"genre_scores_gemma":[0.99860007,0.0006963047,0.000002481312,0.00035210515,0.000056398887,0.00001733072,0.0000019516979,0.000025576186,0.00024776356],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99782145,0.00029705671,0.00029214408,0.00025240102,0.00033194915,0.0010049726],"domain_scores_gemma":[0.99942875,0.00020504816,0.00019898516,0.000092276474,0.000019929541,0.00005500641],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018969816,0.00015009411,0.00023046783,0.00020684367,0.0002876606,0.000034498076,0.0002041947,0.000042809865,0.00011829945],"category_scores_gemma":[0.00017730737,0.00014586438,0.000065715925,0.00023051153,0.000084457206,0.00010071102,0.0000796797,0.0011771878,0.0000041885114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009619634,0.0004269324,0.00065043697,0.000022356275,0.000027760947,0.000037218942,0.00034958796,0.00002019451,0.98310965,0.009856558,0.000029370656,0.0045079403],"study_design_scores_gemma":[0.0132254455,0.0074150306,0.008989784,0.00011410375,0.00009017174,0.0011925367,0.0015497254,0.0006843363,0.87443584,0.09147025,0.00011199853,0.0007207629],"about_ca_topic_score_codex":0.000020845811,"about_ca_topic_score_gemma":0.00023485876,"teacher_disagreement_score":0.10867382,"about_ca_system_score_codex":0.00021025715,"about_ca_system_score_gemma":0.00048747155,"threshold_uncertainty_score":0.5948177},"labels":[],"label_agreement":null},{"id":"W4205659158","doi":"10.1016/j.euroneuro.2021.12.005","title":"Transcriptional biomarkers of response to pharmacological treatments in severe mental disorders: A systematic review","year":2022,"lang":"en","type":"review","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Bipolar disorder; Mood; Mood disorders; PsycINFO; Medicine; Psychiatry; Schizophrenia (object-oriented programming); Major depressive disorder; Psychopharmacology; Adverse effect; Bioinformatics; Clinical psychology; Oncology; Anxiety; Pharmacology; MEDLINE; Biology","score_opus":0.06424858086372821,"score_gpt":0.3640712667311662,"score_spread":0.299822685867438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205659158","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009899524,0.9843552,0.0000013492324,0.0004363358,0.0016638569,0.009222896,0.00044300614,0.00021846466,0.0026689325],"genre_scores_gemma":[0.00035768942,0.991586,0.000017671482,0.0059902724,0.00004472676,0.0011363033,0.000040441424,0.00025546696,0.0005713727],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9756133,0.01939955,0.0020542496,0.0015530746,0.0006386322,0.0007412163],"domain_scores_gemma":[0.9964662,0.0018423336,0.00080802455,0.00055629713,0.000016087559,0.00031105007],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013879148,0.00091208506,0.0028479628,0.0009273223,0.00013761195,0.000025212374,0.0017746013,0.00010350366,0.002652978],"category_scores_gemma":[0.0008505821,0.0007760298,0.0009949916,0.0021975702,0.00023646907,0.0001116777,0.00038464004,0.0008587017,0.00040380875],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004260625,0.0052272202,0.000001614012,0.7238192,0.0010874235,0.0033318093,0.00065720285,0.000011479064,0.06035655,0.000049245533,0.020800322,0.18039732],"study_design_scores_gemma":[0.0032025934,0.0010298347,0.00003372697,0.048336968,0.001862705,0.00046646924,0.000026407844,0.000003032527,0.000014809215,0.0000053756726,0.94418424,0.0008338041],"about_ca_topic_score_codex":0.0000019411157,"about_ca_topic_score_gemma":9.935878e-7,"teacher_disagreement_score":0.92338395,"about_ca_system_score_codex":0.000287281,"about_ca_system_score_gemma":0.00018229442,"threshold_uncertainty_score":0.99946904},"labels":[],"label_agreement":null},{"id":"W4205707429","doi":"10.1016/b978-0-12-821398-8.00007-2","title":"Neural biomarkers of suicidal behavior: from cognition and circuits to cells (and back)","year":2022,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Neuropsychology; Cognition; Psychology; Neuroimaging; Neuroinflammation; Neuroscience; Depression (economics); Clinical psychology; Medicine; Inflammation","score_opus":0.028717075581076185,"score_gpt":0.24394464655428183,"score_spread":0.21522757097320563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205707429","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10135851,0.00039295873,7.5625985e-7,0.000055945744,0.00043966825,0.0010036465,0.0010660331,0.00004377453,0.8956387],"genre_scores_gemma":[0.4055844,0.00019523836,0.000071645096,0.0018908912,0.000112907925,0.00008363416,0.0000633698,0.00014762301,0.5918503],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983411,0.00005792566,0.00033443526,0.0006826197,0.00034672595,0.00023722262],"domain_scores_gemma":[0.9991541,0.00019104466,0.00018147251,0.00027982236,0.00002340888,0.00017014776],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007613803,0.000328533,0.00038583725,0.00019326337,0.00011809531,0.00004611074,0.00021044772,0.0001534614,0.0012139906],"category_scores_gemma":[0.000027439133,0.00034911954,0.000108114335,0.000024445786,0.00029195554,0.000054920092,0.000257714,0.00028035324,0.000053631622],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039494153,0.000018667972,0.000019446485,0.000052166855,0.000020814945,0.000047551177,0.00031220715,1.716285e-7,0.21336308,0.0003646145,0.00011731255,0.7856445],"study_design_scores_gemma":[0.002395986,0.0006944791,0.0019874568,0.00024887748,0.00040715619,0.000071430346,0.000117332595,0.0000134250195,0.13786297,0.0047216397,0.84975386,0.0017253596],"about_ca_topic_score_codex":0.0000067311894,"about_ca_topic_score_gemma":0.000021469597,"teacher_disagreement_score":0.84963655,"about_ca_system_score_codex":0.000023046467,"about_ca_system_score_gemma":0.000035884306,"threshold_uncertainty_score":0.9998961},"labels":[],"label_agreement":null},{"id":"W4205736280","doi":"10.3389/fpsyt.2021.797577","title":"Depression, Estrogens, and Neuroinflammation: A Preclinical Review of Ketamine Treatment for Mood Disorders in Women","year":2022,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Ketamine; Depression (economics); Antidepressant; Neuroinflammation; Mood; Mood disorders; Psychology; Psychiatry; Hormone; Medicine; Neuroscience; Internal medicine; Anxiety","score_opus":0.03688778485381484,"score_gpt":0.3363975204019686,"score_spread":0.29950973554815374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205736280","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001508497,0.9931463,0.000059065103,0.00025826492,0.0027824382,0.0030076988,0.0001483842,0.000026217022,0.0004207827],"genre_scores_gemma":[0.000014090661,0.99602634,0.0018581992,0.00016143046,0.000060058326,0.0016926038,0.000048752776,0.000058287424,0.00008026148],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99681705,0.0004932496,0.0012085331,0.00084731606,0.00023427825,0.00039959658],"domain_scores_gemma":[0.9984238,0.0004012634,0.000561791,0.00051036046,0.0000065293375,0.00009626837],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003699767,0.00042276035,0.0017279355,0.00036807047,0.00006619343,0.000014121589,0.000414776,0.00016913856,0.000080578946],"category_scores_gemma":[0.00057266187,0.00036040286,0.00039128892,0.0007140069,0.00012067558,0.000082870734,0.00010507877,0.00030917587,0.0000010053444],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069762784,0.00041652768,0.001047454,0.041370377,0.000026732472,0.000001159779,0.00006924165,0.0000010506994,1.6142917e-7,0.00005177479,0.005765777,0.95118],"study_design_scores_gemma":[0.0016642845,0.00031730902,0.00016484516,0.017500395,0.00010478075,0.000010453312,0.000078387624,0.000034451146,8.3828394e-7,0.0010673403,0.9787156,0.00034132888],"about_ca_topic_score_codex":0.0000038119033,"about_ca_topic_score_gemma":0.000029442572,"teacher_disagreement_score":0.9729498,"about_ca_system_score_codex":0.00013554208,"about_ca_system_score_gemma":0.000354285,"threshold_uncertainty_score":0.9998848},"labels":[],"label_agreement":null},{"id":"W4206032893","doi":"10.2217/fmb-2021-0277","title":"Bucillamine in the Treatment of Patients with Mild to Moderate COVID-19: An Interview with Michael Frank","year":2022,"lang":"en","type":"article","venue":"Future Microbiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Revive Therapeutics (Canada)","funders":"","keywords":"Management; Officer; Corporation; Chief executive officer; Coronavirus disease 2019 (COVID-19); Sociology; Medicine; Law; Political science; Economics","score_opus":0.02174665227518476,"score_gpt":0.2531373572291635,"score_spread":0.2313907049539787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206032893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941504,0.0002244551,0.000102228674,0.0042872685,0.00013459935,0.0007116755,0.00032200816,0.00001855323,0.000048830898],"genre_scores_gemma":[0.9790195,0.000032663447,0.00014024455,0.020479798,0.000033571734,0.000117531024,0.00010257235,0.00001427567,0.000059819464],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99866474,0.00048311285,0.00015616776,0.00039458182,0.000066164765,0.000235242],"domain_scores_gemma":[0.99945784,0.00007592563,0.00007289203,0.000306024,0.00001631349,0.00007098021],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008438647,0.00016541341,0.00022643976,0.000102591526,0.00013669005,0.000008362078,0.00034463717,0.0000373808,0.0002377503],"category_scores_gemma":[0.000015960466,0.000089008456,0.000032606313,0.00036656327,0.00010902954,0.00002821674,0.00004583161,0.00010248593,0.000004189426],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01794838,0.018950824,0.028533531,0.00030990003,0.00019415782,0.00035308566,0.14854737,0.013156404,0.7224847,0.0027124987,0.019134115,0.027675055],"study_design_scores_gemma":[0.011756102,0.023725258,0.016990732,0.000019883966,0.000032467135,0.00012475748,0.005478094,0.000049974526,0.028208094,0.00009144049,0.91284174,0.00068145205],"about_ca_topic_score_codex":0.000049438968,"about_ca_topic_score_gemma":0.0006297574,"teacher_disagreement_score":0.89370763,"about_ca_system_score_codex":0.00007398809,"about_ca_system_score_gemma":0.00007048241,"threshold_uncertainty_score":0.36296594},"labels":[],"label_agreement":null},{"id":"W4206184287","doi":"10.1101/2022.01.14.476359","title":"Kynurenine metabolism is altered in <i>mdx</i> mice: a potential muscle to brain connection","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St Joseph's Health Care; Brock University","funders":"","keywords":"Kynurenine; Endocrinology; Kynurenine pathway; Internal medicine; Duchenne muscular dystrophy; mdx mouse; Metabolism; Neuroprotection; Muscular dystrophy; Dystrophin; Elevated plus maze; Biology; Chemistry; Medicine; Anxiety; Biochemistry; Tryptophan; Amino acid; Psychiatry","score_opus":0.016246256858700743,"score_gpt":0.2368188427796156,"score_spread":0.22057258592091486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206184287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98889625,0.00041022067,0.00059776095,0.0035926688,0.0039803567,0.0013721286,0.00061416917,0.00050021947,0.00003623314],"genre_scores_gemma":[0.9890735,0.000108821565,0.0008187549,0.008717036,0.0005592032,0.000511242,6.003429e-7,0.00017112042,0.000039693226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9951411,0.0004995124,0.0007085065,0.0020200931,0.00074675516,0.0008840513],"domain_scores_gemma":[0.9977396,0.00014288677,0.00036751854,0.0012730272,0.000116537,0.0003604138],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00061031815,0.00067925925,0.0007018631,0.0008031595,0.00028589705,0.00030445465,0.0011369191,0.00039370757,0.00081383553],"category_scores_gemma":[0.0008694256,0.0008164694,0.00026044244,0.0016717773,0.00011346359,0.00022967049,0.001174939,0.0012903718,0.0001473484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011030611,0.00025554214,0.000088711124,0.000091962036,0.00002099158,0.00009331645,0.00007996771,0.00046327972,0.99375385,0.00046484137,0.0045690066,0.000008197698],"study_design_scores_gemma":[0.0018742866,0.000109343666,0.058894884,0.00012380104,0.000043532622,7.5627625e-8,0.000020628515,0.0005724976,0.85583097,0.000018142018,0.08117229,0.001339578],"about_ca_topic_score_codex":0.00020424095,"about_ca_topic_score_gemma":0.00001633383,"teacher_disagreement_score":0.13792294,"about_ca_system_score_codex":0.000281928,"about_ca_system_score_gemma":0.0004249828,"threshold_uncertainty_score":0.99942863},"labels":[],"label_agreement":null},{"id":"W4206254523","doi":"10.1016/j.psychres.2021.114382","title":"Complete blood count inflammatory markers in treatment-resistant schizophrenia: Evidence of association between treatment responsiveness and levels of inflammation","year":2021,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Royal Ottawa Mental Health Centre","funders":"","keywords":"Schizophrenia (object-oriented programming); Inflammation; Medicine; Internal medicine; Systemic inflammation; Neutrophil to lymphocyte ratio; Pathophysiology; Lymphocyte; Immunology; Gastroenterology; Psychiatry","score_opus":0.1022340906606796,"score_gpt":0.3599819569432209,"score_spread":0.2577478662825413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206254523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99610627,0.0014851673,0.0000036678503,0.0014296211,0.000086813605,0.00049827935,0.0001560595,0.000014493608,0.00021965863],"genre_scores_gemma":[0.99837714,0.0010415583,0.00021469993,0.000009473921,0.000058326867,0.000047765643,0.0000062175486,0.000015908648,0.00022892264],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9964224,0.0014159551,0.00053693354,0.000458206,0.0007916783,0.00037480853],"domain_scores_gemma":[0.99654436,0.0025252318,0.00023154693,0.000365018,0.00024730837,0.00008654059],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011139312,0.00016215204,0.00036383476,0.00038610175,0.0001333916,0.000044159064,0.00017747599,0.00011989173,0.000049559865],"category_scores_gemma":[0.0015432929,0.00015017217,0.00008034262,0.00088227325,0.00019134395,0.00021400535,0.000077557845,0.00016730803,0.0000065417294],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012234009,0.0002443586,0.35144478,0.00024383512,0.00007294192,0.000016630478,0.0004611365,0.000012906856,0.6407627,0.0009638371,0.000017275246,0.00453622],"study_design_scores_gemma":[0.0032503563,0.0008719435,0.81673163,0.00041701962,0.000034766486,0.000002825518,0.00045705572,0.000046832072,0.17647274,0.00134624,0.00023146301,0.00013714247],"about_ca_topic_score_codex":0.00013032506,"about_ca_topic_score_gemma":0.00096226716,"teacher_disagreement_score":0.46528685,"about_ca_system_score_codex":0.00033153736,"about_ca_system_score_gemma":0.00090498035,"threshold_uncertainty_score":0.6123843},"labels":[],"label_agreement":null},{"id":"W4206386241","doi":"10.1038/s41398-021-01712-0","title":"Whole blood transcriptional signatures associated with rapid antidepressant response to ketamine in patients with treatment resistant depression","year":2022,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; Kurt und Senta Herrmann Stiftung; National Alliance for Research on Schizophrenia and Depression; Icahn School of Medicine at Mount Sinai; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Ketamine; Antidepressant; Treatment-resistant depression; Whole blood; Depression (economics); Animal models of depression; Gene expression; Metabotropic receptor","score_opus":0.011068583074258204,"score_gpt":0.22302038270019947,"score_spread":0.21195179962594127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206386241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949679,0.00024628697,0.00007398591,0.0025987718,0.00014360485,0.0007740962,0.0007720177,0.000075331656,0.00034805507],"genre_scores_gemma":[0.99815893,0.000002431191,0.00048179488,0.0007776512,0.00002201388,0.0001392822,0.00018096993,0.000038453156,0.00019847577],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9973772,0.00044325335,0.00029130955,0.0006177875,0.00093760167,0.00033281828],"domain_scores_gemma":[0.9993043,0.00024640307,0.00008946376,0.00021704093,0.000033551292,0.00010925712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019059714,0.00025420383,0.00021644098,0.00029087052,0.00036610774,0.00003094394,0.00022009028,0.000053668027,0.00031448403],"category_scores_gemma":[0.00003259223,0.00019705328,0.00007453883,0.00074786367,0.00006809433,0.0001487048,0.000013014824,0.00023715313,0.0000042698543],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.10381347,0.013069307,0.63703215,0.000030268699,0.00017803343,0.00006950281,0.00219808,0.050243672,0.18954454,0.0017103108,0.00068267965,0.0014279813],"study_design_scores_gemma":[0.011844094,0.002074766,0.98296225,0.000054270695,0.000031151652,0.0000024879728,0.00006829323,0.000079216195,0.0010676122,0.00026989233,0.0012430842,0.00030286267],"about_ca_topic_score_codex":0.000012335927,"about_ca_topic_score_gemma":0.0001987136,"teacher_disagreement_score":0.3459301,"about_ca_system_score_codex":0.00006400254,"about_ca_system_score_gemma":0.00022557618,"threshold_uncertainty_score":0.80355996},"labels":[],"label_agreement":null},{"id":"W4206634797","doi":"10.1007/s12035-021-02692-4","title":"Correction to: Increased Levels of Plasma Tumor Necrosis Factor-α Mediate Schizophrenia Symptom Dimensions and Neurocognitive Impairments and Are Inversely Associated with Natural IgM Directed to Malondialdehyde and Paraoxonase 1 Activity","year":2022,"lang":"en","type":"erratum","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Paraoxonase; Malondialdehyde; Neurocognitive; Schizophrenia (object-oriented programming); Tumor necrosis factor alpha; Neurology; Medicine; Plasma levels; Psychology; Internal medicine; Clinical psychology; Immunology; Endocrinology; Psychiatry; Oxidative stress; Cognition","score_opus":0.012423348816778994,"score_gpt":0.22962529085330113,"score_spread":0.21720194203652213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206634797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921769,0.000047113117,0.0000039532865,0.00020492738,0.0039580776,0.0012391014,0.0021435954,0.00016011843,0.00006620987],"genre_scores_gemma":[0.9964407,0.000049505827,0.000021606082,0.0025342586,0.00002723416,0.00011423083,0.0001537954,0.00009512318,0.000563518],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99593157,0.0013303688,0.00033733682,0.0014751444,0.00031874212,0.00060686923],"domain_scores_gemma":[0.99770796,0.0010129707,0.0004852231,0.00030348863,0.00009970342,0.00039065612],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010270142,0.0006613886,0.0008900787,0.0005392951,0.0003063783,0.00006573367,0.00023989225,0.00024345417,0.000032226224],"category_scores_gemma":[0.0032688798,0.00062399637,0.000090031885,0.00078809325,0.0004052337,0.00011026045,0.0006415447,0.0011452911,0.0000027908418],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019934422,0.00028161245,0.001949045,0.00006806257,0.00012628622,0.00069467205,0.0003481846,0.0000153392,0.9822718,0.0000037536834,0.011597459,0.0006503569],"study_design_scores_gemma":[0.0057004564,0.0040120445,0.76944137,0.00041276033,0.0002580998,0.0004275032,0.00009888329,0.00090354186,0.21599425,0.000036759975,0.0011249789,0.0015893313],"about_ca_topic_score_codex":0.0002083143,"about_ca_topic_score_gemma":0.00038538483,"teacher_disagreement_score":0.76749235,"about_ca_system_score_codex":0.00007252871,"about_ca_system_score_gemma":0.00017894467,"threshold_uncertainty_score":0.99962115},"labels":[],"label_agreement":null},{"id":"W4206875504","doi":"","title":"Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer&rsquo;s Disease","year":2021,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Immunity; Antimicrobial; Disease; Medicine; Neuroscience; Immunology; Immune system; Biology; Microbiology; Pathology","score_opus":0.2674106432461172,"score_gpt":0.5123210854817976,"score_spread":0.24491044223568037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206875504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9776951,0.017733354,0.00010247402,0.0025215172,0.0003773828,0.001151592,0.0001695856,0.000016882583,0.00023212083],"genre_scores_gemma":[0.991319,0.0069176126,0.000046588957,0.0014208594,0.00009537247,0.000082927065,0.000013677549,0.000032221567,0.0000717518],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99719995,0.00089125725,0.0006943888,0.00039591177,0.0004197537,0.00039875897],"domain_scores_gemma":[0.9960607,0.0025353655,0.00054204563,0.0006240311,0.00012307835,0.0001147367],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010199235,0.00026674414,0.0005022258,0.0002203208,0.00046490255,0.0006224391,0.0022384992,0.00005442387,0.00097286183],"category_scores_gemma":[0.0016330989,0.00016582538,0.00035702996,0.001010678,0.00026812957,0.0007109721,0.00032985382,0.00020645357,0.0000029693329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005721582,0.0016879147,0.027436148,0.00006325066,0.00013040475,0.00007368553,0.0018174006,0.0006197982,0.934028,0.00013952582,0.019978328,0.013453373],"study_design_scores_gemma":[0.002208862,0.000042019707,0.39244896,0.00017617544,0.00014417854,0.000012429561,0.0008020684,0.00054571923,0.5918344,0.002120742,0.009292773,0.0003716659],"about_ca_topic_score_codex":0.0004052764,"about_ca_topic_score_gemma":0.000056393284,"teacher_disagreement_score":0.3650128,"about_ca_system_score_codex":0.00004629765,"about_ca_system_score_gemma":0.00025479708,"threshold_uncertainty_score":0.9999404},"labels":[],"label_agreement":null},{"id":"W4207056731","doi":"10.2196/preprints.32234","title":"Microbial Ecosystem Therapeutic-2 Intervention in People With Major Depressive Disorder and Generalized Anxiety Disorder: Phase 1, Open-Label Study (Preprint)","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; Providence Health Care","funders":"","keywords":"Tolerability; Adverse effect; Anxiety; Generalized anxiety disorder; Major depressive disorder; Medicine; Internal medicine; Psychiatry; Microbiome; Depression (economics); Psychology; Bioinformatics; Biology; Mood","score_opus":0.02878884941412745,"score_gpt":0.31025567761253725,"score_spread":0.2814668281984098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4207056731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98691815,0.0010108376,0.0040566283,0.0003326929,0.00037931124,0.0065646362,0.00010538951,0.00014972493,0.00048260114],"genre_scores_gemma":[0.9966316,0.00048640906,0.0005245408,0.00034586684,0.00003444054,0.0011955916,0.00007754017,0.000101919,0.00060209446],"study_design_codex":"observational","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99452174,0.0011986131,0.0008739153,0.002400633,0.00041546382,0.00058964273],"domain_scores_gemma":[0.99794805,0.00015594115,0.00046375798,0.0011783891,0.00009933433,0.00015450547],"candidate_categories":["metaepi_narrow","scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.0004635968,0.0007473074,0.0010320359,0.00024899436,0.00026257508,0.0012317733,0.0013140854,0.0002884236,0.00045416443],"category_scores_gemma":[0.0001228535,0.00062382576,0.00014250689,0.00051334937,0.000110337794,0.0004494092,0.0036751635,0.000821228,0.000012135925],"study_design_candidate":"randomized_trial","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010003375,0.15174681,0.40506026,0.0033894014,0.0013294045,0.00059102825,0.03260096,0.0030088297,0.16799827,0.001691918,0.0004121233,0.2221676],"study_design_scores_gemma":[0.60827833,0.007170604,0.12954773,0.003833465,0.0010315323,0.00057317753,0.06835027,0.04293555,0.12092554,0.0021949413,0.0042215367,0.010937297],"about_ca_topic_score_codex":0.0036063595,"about_ca_topic_score_gemma":0.08589825,"teacher_disagreement_score":0.598275,"about_ca_system_score_codex":0.00010951573,"about_ca_system_score_gemma":0.00019095375,"threshold_uncertainty_score":0.99980503},"labels":[],"label_agreement":null},{"id":"W4207057402","doi":"10.1038/s41398-021-01449-w","title":"Correction: A randomised clinical trial of methotrexate points to possible efficacy and adaptive immune dysfunction in psychosis","year":2021,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Psychosis; Methotrexate; Clinical trial; Medicine; Immune system; Psychology; Psychiatry; Intensive care medicine; Internal medicine; Immunology","score_opus":0.05647954619300199,"score_gpt":0.34699423402078955,"score_spread":0.29051468782778755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4207057402","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97916096,0.00031671737,0.0045716474,0.0052949465,0.005249372,0.0009010429,0.00001857208,0.000040297433,0.0044464637],"genre_scores_gemma":[0.9925245,0.00008651855,0.006116596,0.00075481867,0.00018704848,0.000034529763,0.000007143779,0.000016714843,0.0002720981],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99793845,0.00047211655,0.00068453315,0.00047439334,0.00026768155,0.0001627997],"domain_scores_gemma":[0.9986246,0.0009388544,0.00012398,0.00017806735,0.000047013655,0.00008745914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049686985,0.00013694708,0.00031793822,0.00015157142,0.00006950424,0.000020581205,0.00009199822,0.00010450963,0.00018792329],"category_scores_gemma":[0.00044717386,0.00013687651,0.0001646779,0.00069771585,0.00008419323,0.000118949334,0.000011844001,0.00021967947,0.000017804286],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.8211675,0.0066316617,0.010589769,0.00008954399,0.00015351352,0.000015331547,0.001731881,0.0010465881,0.04978924,0.0120536545,0.004154037,0.09257727],"study_design_scores_gemma":[0.54831785,0.0013336724,0.4283751,0.00020791045,0.0000567971,0.000023249568,0.00024979722,0.0021454482,0.0076879966,0.010331214,0.0008319903,0.00043897514],"about_ca_topic_score_codex":0.000013407955,"about_ca_topic_score_gemma":0.0000859726,"teacher_disagreement_score":0.41778532,"about_ca_system_score_codex":0.0000078537,"about_ca_system_score_gemma":0.00015320467,"threshold_uncertainty_score":0.5581662},"labels":[],"label_agreement":null},{"id":"W4210667621","doi":"10.1093/schbul/sbac012","title":"Central Oxidative Stress and Early Vocational Outcomes in First Episode Psychosis: A 7-Tesla Magnetic Resonance Spectroscopy Study of Glutathione","year":2022,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Victoria Hospital; Robarts Clinical Trials; London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"Academic Medical Organization of Southwestern Ontario; Schulich School of Medicine and Dentistry; Canadian Institutes of Health Research; Office of Nuclear Energy Technologies; Compute Canada; McGill University","keywords":"Psychosis; Glutathione; Medicine; Confounding; Schizophrenia (object-oriented programming); Oxidative stress; Internal medicine; Cohort; Psychology; Psychiatry; Chemistry","score_opus":0.011779097119338649,"score_gpt":0.24388207423235372,"score_spread":0.23210297711301509,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210667621","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957014,0.0007569334,0.000007057284,0.0023224137,0.00016020109,0.0007132764,0.00011842728,0.00004149147,0.00017881356],"genre_scores_gemma":[0.99872404,0.00005159576,0.0005045392,0.00021626796,0.000021480108,0.00023683273,0.0000026379566,0.000024022005,0.00021858208],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976948,0.00033369215,0.00040528065,0.00063394214,0.0005364782,0.0003958377],"domain_scores_gemma":[0.9991275,0.00032122477,0.00015128561,0.0002986131,0.000019191644,0.000082166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016653154,0.0002163361,0.00031268588,0.00020170827,0.00026642164,0.000040153987,0.0004009457,0.000033664714,0.0005739336],"category_scores_gemma":[0.00025337885,0.00022019348,0.000051612755,0.0004974594,0.00016668122,0.00005482021,0.00021894168,0.00035521595,0.000014576367],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035902036,0.007236691,0.95560265,0.00007123745,0.000021437552,0.00009466401,0.009956842,0.00031513776,0.012372046,0.004684686,0.0021004907,0.003953939],"study_design_scores_gemma":[0.0049699116,0.0011468717,0.98501885,0.00003359842,0.000007784919,0.000005827028,0.0014785231,0.000043712214,0.005107996,0.00059538736,0.0013328284,0.0002587148],"about_ca_topic_score_codex":0.00051019166,"about_ca_topic_score_gemma":0.0006629345,"teacher_disagreement_score":0.02941622,"about_ca_system_score_codex":0.00005070177,"about_ca_system_score_gemma":0.000027919645,"threshold_uncertainty_score":0.897923},"labels":[],"label_agreement":null},{"id":"W4210775271","doi":"10.1016/j.bpsgos.2022.01.006","title":"Systemic Inflammatory Biomarkers in DSM-5–Defined Disorders and COVID-19: Evidence From Published Meta-analyses","year":2022,"lang":"en","type":"review","venue":"Biological Psychiatry Global Open Science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; Canada Research Chairs","keywords":"Coronavirus disease 2019 (COVID-19); Medicine; Outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); C-reactive protein; Interleukin; Pandemic; Interleukin 6; Coronavirus; Inflammation; Systemic inflammation; 2019-20 coronavirus outbreak; Immunology; Meta-analysis; Virology; Internal medicine; Disease; Cytokine","score_opus":0.3748526414419858,"score_gpt":0.46077403743740414,"score_spread":0.08592139599541831,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210775271","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010980306,0.9896243,0.00004861759,0.0014390035,0.0013581702,0.0031030725,0.0006107725,0.00015560584,0.0025624153],"genre_scores_gemma":[0.0047936887,0.990967,0.00059666304,0.0028068435,0.000052420753,0.00068770524,0.00003842995,0.000025394536,0.00003187738],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98892206,0.0027347049,0.0017423789,0.0041943477,0.0012701632,0.0011363566],"domain_scores_gemma":[0.99337906,0.0028585175,0.0012065952,0.0015783155,0.00003317129,0.0009443549],"candidate_categories":["metaresearch","metaepi_narrow","sts","scholarly_communication","open_science","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0040664766,0.001037225,0.0031205642,0.00050218095,0.0009343972,0.0016089893,0.010515885,0.00044404087,0.0018874878],"category_scores_gemma":[0.02099611,0.0006572085,0.0009127801,0.0068936227,0.0029662754,0.001529105,0.0053309468,0.0007187056,0.00007463759],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015091052,0.0031370805,0.030532772,0.014394584,0.004391331,0.0005404868,0.000490342,0.00027007933,0.0010301736,0.05445713,0.029771708,0.8594752],"study_design_scores_gemma":[0.0011520487,0.00037974122,0.0016346679,0.0014802079,0.0015325863,0.00016992413,0.00057731604,0.000058865753,0.0000025454956,0.013985558,0.9767819,0.0022446194],"about_ca_topic_score_codex":0.0016509166,"about_ca_topic_score_gemma":0.00061417214,"teacher_disagreement_score":0.9470102,"about_ca_system_score_codex":0.0008524535,"about_ca_system_score_gemma":0.004396027,"threshold_uncertainty_score":0.9997471},"labels":[],"label_agreement":null},{"id":"W4210984459","doi":"10.1016/j.jad.2022.02.025","title":"Immune response to vaccination in adults with mental disorders: A systematic review","year":2022,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Vaccination; Medicine; Immune system; Immunology; Major depressive disorder; PsycINFO; Immunity; Psychiatry; MEDLINE; Cognition","score_opus":0.015898494379090897,"score_gpt":0.306092796079863,"score_spread":0.2901943017007721,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210984459","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003163589,0.99103975,0.000043576176,0.0004760769,0.0003358085,0.0073427907,0.00003538033,0.000026411473,0.00038383497],"genre_scores_gemma":[0.0012665724,0.99747473,0.000023623654,0.00034970083,0.00002012483,0.00067391415,0.000008791353,0.00010479534,0.000077751465],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.99232554,0.003972767,0.0016006452,0.0006105371,0.0010239255,0.0004665763],"domain_scores_gemma":[0.9949495,0.0022924114,0.0020621363,0.00047524672,0.000059600457,0.00016108561],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019542906,0.00066897017,0.0030686953,0.0013399178,0.0001670448,0.00006205222,0.0009897891,0.00012589784,0.0002529404],"category_scores_gemma":[0.005634097,0.00047854037,0.0008563525,0.002839201,0.00005580685,0.0003897294,0.00017275092,0.0010138626,0.00003038076],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013071987,0.00081357016,0.0000024746234,0.64635485,0.00015367077,0.00007408972,0.0013928377,0.00001671882,0.000010453062,0.00003735154,0.00040857625,0.3494282],"study_design_scores_gemma":[0.0033164206,0.0037070678,0.000086197426,0.815381,0.00083119055,0.0004137077,0.0015331117,0.000006421408,0.0000076313845,0.0001182188,0.17351052,0.0010885102],"about_ca_topic_score_codex":0.000024076708,"about_ca_topic_score_gemma":0.00020769499,"teacher_disagreement_score":0.3483397,"about_ca_system_score_codex":0.0008161517,"about_ca_system_score_gemma":0.00046290265,"threshold_uncertainty_score":0.99976665},"labels":[],"label_agreement":null},{"id":"W4211232539","doi":"10.1007/978-1-4939-7828-1_14","title":"The MRL Model: A Valuable Tool in Studies of Autoimmunity-Brain Interactions","year":2018,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Autoimmunity; Neurodegeneration; Immune system; Neuroscience; Immunology; Neuroimmunology; Disease; Autoimmune disease; Systemic lupus erythematosus; Medicine; Antibody; Biology; Pathology","score_opus":0.2143297251227669,"score_gpt":0.5378907155896133,"score_spread":0.3235609904668464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4211232539","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005220942,0.92493296,0.07289714,0.00019878814,0.0004945366,0.00069577276,0.000015974161,0.000025803893,0.0006868088],"genre_scores_gemma":[0.0000033739598,0.89383304,0.10505331,0.00042162402,0.000015045836,0.00028649738,0.0000044376425,0.000035938927,0.00034673544],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9885339,0.009482731,0.00090805907,0.00055988284,0.000094900526,0.0004205027],"domain_scores_gemma":[0.9925557,0.006225486,0.00038381194,0.0007713363,0.00004579672,0.000017865172],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0032812757,0.0003353589,0.0013179176,0.0004324882,0.00011825146,0.00001687766,0.00091126363,0.0002715338,0.0000108216245],"category_scores_gemma":[0.013018978,0.00022270443,0.00034118633,0.0009502598,0.00091320917,0.00003428749,0.00051729585,0.0006639204,0.0000070174674],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018769348,0.00015375108,0.00000129658,0.0016807186,0.00009214416,0.000020517877,0.0005094311,0.00008141624,0.021849118,0.020948108,0.0004631208,0.9541816],"study_design_scores_gemma":[0.00024587288,0.00012001188,3.7766762e-7,0.0015796839,0.000045994475,0.00002604054,0.0001243804,0.0009771636,0.0036976251,0.050289977,0.942573,0.00031988535],"about_ca_topic_score_codex":0.0000214426,"about_ca_topic_score_gemma":0.000064231834,"teacher_disagreement_score":0.9538617,"about_ca_system_score_codex":0.000112568814,"about_ca_system_score_gemma":0.0001999517,"threshold_uncertainty_score":0.9952948},"labels":[],"label_agreement":null},{"id":"W4212792064","doi":"10.1093/jcag/gwab049.247","title":"A248 THE ROLE OF DIETARY TRYPTOPHAN IN INDOLE AND KYNURENINE PRODUCTION AND IMMUNE MODULATION IN HEALTHY INDIVIDUALS","year":2022,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Kynurenine; Tryptophan; Placebo; Crossover study; Internal medicine; Kynurenine pathway; Medicine; Serotonin; Immune system; Indoleamine 2,3-dioxygenase; Urinary system; Feces; Endocrinology; Immunology; Physiology; Biology; Biochemistry; Receptor; Amino acid","score_opus":0.009934270400292704,"score_gpt":0.2210652620759522,"score_spread":0.2111309916756595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212792064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9817572,0.0000894132,5.3537343e-7,0.017782778,0.0001823432,0.00014824327,0.000018012712,8.3432025e-7,0.000020588272],"genre_scores_gemma":[0.9993035,0.00003388189,0.000013091965,0.00060100784,0.000022554888,0.00000369199,8.029313e-7,0.0000044322605,0.000017023602],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998399,0.00071466307,0.00040739833,0.00009318592,0.00021829322,0.0001674275],"domain_scores_gemma":[0.9989966,0.0000814241,0.0007719792,0.000074554606,0.00003398439,0.000041470754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010231665,0.00005640842,0.00018799258,0.00029747782,0.00010808441,0.0000070278497,0.00016416059,0.000035749876,0.000009322613],"category_scores_gemma":[0.0005827265,0.00004390936,0.00003674059,0.00022732743,0.000067554225,0.00008626934,0.000049514754,0.00029733827,4.66451e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029881467,0.000062610656,0.9735846,0.0000064918045,0.000011300256,0.0000010636913,0.0013814593,0.0020954171,0.021613406,0.000087535795,0.00008788713,0.0007694227],"study_design_scores_gemma":[0.00092648994,0.00046247896,0.9956235,0.000011260841,0.0000049344194,0.00003236122,0.00043108274,0.00024395966,0.00094934256,0.0011927764,0.00010000328,0.000021797752],"about_ca_topic_score_codex":0.002637986,"about_ca_topic_score_gemma":0.11876245,"teacher_disagreement_score":0.11612446,"about_ca_system_score_codex":0.00029533356,"about_ca_system_score_gemma":0.0001159093,"threshold_uncertainty_score":0.8973178},"labels":[],"label_agreement":null},{"id":"W4212841037","doi":"10.1016/j.bbi.2022.02.020","title":"Lifetime pathogen burden, inflammatory markers, and depression in community-dwelling older adults","year":2022,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Biomedical Research Council; National Medical Research Council; Shandong University","keywords":"Medicine; Depression (economics); Confounding; Marital status; Internal medicine; Odds ratio; Immunology; Geriatric Depression Scale; Mental health; Anxiety; Psychiatry; Environmental health; Population; Depressive symptoms","score_opus":0.014275864214941252,"score_gpt":0.2487107769552019,"score_spread":0.23443491274026065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212841037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982907,0.00053488667,0.0000041916046,0.00013192906,0.0001134222,0.0004811366,0.000047737816,0.00007027935,0.00032572838],"genre_scores_gemma":[0.9989687,0.00010779228,0.00003308405,0.00054241816,0.000017034106,0.000121793455,0.000023660123,0.00002601847,0.00015947949],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99732643,0.0015864545,0.00026561748,0.00028691455,0.00023183106,0.0003027607],"domain_scores_gemma":[0.9988253,0.0005520371,0.00008522493,0.00041855036,0.000014789287,0.00010406639],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000762177,0.00019046721,0.0001896723,0.00017778187,0.0011823213,0.00006039872,0.0003540112,0.00007426304,0.00018365456],"category_scores_gemma":[0.00032968126,0.00020185833,0.000042416425,0.0002530422,0.00019303552,0.00018875384,0.00078801165,0.0010584235,0.0000033570195],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007292484,0.001270891,0.27294064,0.00018384015,0.000006004858,0.00019565005,0.029168194,0.000041088715,0.58164847,0.00007978551,0.00082425645,0.11291198],"study_design_scores_gemma":[0.002402569,0.00013823889,0.97693944,0.00009253159,0.000010080099,0.000081221886,0.012494229,0.00021901421,0.0056345616,0.00007983779,0.0015328897,0.0003753885],"about_ca_topic_score_codex":0.00055622926,"about_ca_topic_score_gemma":0.00004765131,"teacher_disagreement_score":0.7039988,"about_ca_system_score_codex":0.00003406277,"about_ca_system_score_gemma":0.000030093906,"threshold_uncertainty_score":0.90935796},"labels":[],"label_agreement":null},{"id":"W4212849195","doi":"10.29169/1927-5951.2019.09.04.3","title":"Study of Mental Illness in Rat Model of Sodium Azide Induced Oxidative Stress","year":2019,"lang":"en","type":"article","venue":"Journal of Pharmacy and Nutrition Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Oxidative stress; Sodium azide; Reactive oxygen species; Chemistry; Hydrogen peroxide; Morris water navigation task; Antioxidant; Elevated plus maze; Catalase; Nitric oxide; Open field; Pharmacology; Biochemistry; Internal medicine; Psychology; Medicine; Anxiety; Hippocampus; Psychiatry; Organic chemistry","score_opus":0.08278429600237162,"score_gpt":0.3617355753042896,"score_spread":0.278951279301918,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212849195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991374,0.00009203071,0.0000070948795,0.00018810618,0.00018518149,0.00024124725,0.000010026528,0.0000019040124,0.00013698173],"genre_scores_gemma":[0.99964386,0.00022155703,0.000041594125,0.00006551403,0.000014159244,0.0000020110797,1.09492454e-7,0.000002218979,0.000008966249],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878865,0.00013391723,0.00038351232,0.0001448039,0.00043875564,0.000110356756],"domain_scores_gemma":[0.999348,0.00013262396,0.00037147157,0.00004402029,0.000059769118,0.000044115877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042251858,0.000071694725,0.00020123745,0.0002881543,0.00006309284,0.000022241877,0.0002467466,0.000014023418,0.000023089828],"category_scores_gemma":[0.000059851176,0.000054648597,0.000037166876,0.00042703646,0.00017814696,0.0006903903,0.000040526596,0.0001148232,5.058804e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030885727,0.0013252246,0.008438393,0.000037880967,0.0000025442769,0.0000035146477,0.0037089856,0.00014042019,0.98530895,0.00009283812,0.000023859644,0.00060852943],"study_design_scores_gemma":[0.0048460746,0.00065849914,0.00062703213,0.00008423378,0.0000046072632,0.000010292732,0.014116558,0.0024306898,0.9766589,0.00048055747,0.000013588506,0.000068973386],"about_ca_topic_score_codex":0.000013278409,"about_ca_topic_score_gemma":0.000007951627,"teacher_disagreement_score":0.010407573,"about_ca_system_score_codex":0.000010041186,"about_ca_system_score_gemma":0.00005769675,"threshold_uncertainty_score":0.22285052},"labels":[],"label_agreement":null},{"id":"W4212892476","doi":"10.3389/fnbeh.2022.769322","title":"Lack of Vesicular Zinc Does Not Affect the Behavioral Phenotype of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation Mice","year":2022,"lang":"en","type":"article","venue":"Frontiers in Behavioral Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Children's Hospital Research Institute","keywords":"Affect (linguistics); Immune system; Phenotype; Cell biology; Zinc; Chemistry; Biology; Immunology; Psychology; Biochemistry; Communication","score_opus":0.062276849580275496,"score_gpt":0.31736801844195983,"score_spread":0.2550911688616843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212892476","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99607426,0.000042509393,0.00016321322,0.00025429548,0.002618903,0.00063433393,0.0001153056,0.00005102805,0.00004613649],"genre_scores_gemma":[0.9990433,0.000015631098,0.00022662121,0.0004559509,0.000020893052,0.00007478966,0.0000034405266,0.000033339093,0.00012603398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965466,0.00051574304,0.0006119591,0.00073022756,0.0010465456,0.0005488862],"domain_scores_gemma":[0.9986705,0.000070692986,0.0005139061,0.0006315852,0.00003384082,0.000079463854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041842242,0.00028415956,0.0004115124,0.0003304804,0.00041911937,0.00005850745,0.0016089701,0.00007025944,0.00003863311],"category_scores_gemma":[0.00013049378,0.0002182845,0.00018132414,0.0014180961,0.00074033206,0.0004612556,0.00048925314,0.00052152365,0.0000016450092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023011032,0.00058678596,0.016956784,0.000013753792,7.386431e-7,0.000015108103,0.0005358405,0.00008437869,0.9788177,0.0001141013,0.00009311979,0.0025515924],"study_design_scores_gemma":[0.0006276299,0.0005401112,0.12745997,0.000016783886,0.000015494397,0.000010617208,0.0004910928,0.00028523622,0.87014574,0.00008171476,0.00010972767,0.00021589002],"about_ca_topic_score_codex":0.00042469354,"about_ca_topic_score_gemma":0.000009721737,"teacher_disagreement_score":0.11050319,"about_ca_system_score_codex":0.00011902461,"about_ca_system_score_gemma":0.00013279378,"threshold_uncertainty_score":0.8901384},"labels":[],"label_agreement":null},{"id":"W4212905578","doi":"10.1016/j.jad.2022.02.041","title":"The impact of physical conditions on the incidence of major depressive disorder in Chinese university students: Results from a longitudinal study","year":2022,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Ottawa","funders":"","keywords":"Major depressive disorder; Longitudinal study; CIDI; Medicine; Confounding; Depression (economics); Cross-sectional study; Incidence (geometry); Comorbidity; Psychiatry; Clinical psychology; Internal medicine; National Comorbidity Survey; Cognition","score_opus":0.013308995104989407,"score_gpt":0.31563275400686275,"score_spread":0.30232375890187335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212905578","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99846673,0.00004567989,0.000021418922,0.0003242943,0.00008486162,0.00061005505,0.00024738096,0.000004720287,0.00019488254],"genre_scores_gemma":[0.9998989,0.00003092436,0.0000011754746,0.000018934601,0.000016682267,0.000007851192,0.0000014836215,0.000010731266,0.000013313342],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971586,0.0012559468,0.00034668046,0.00025010068,0.00079048885,0.00019820091],"domain_scores_gemma":[0.99359316,0.005214301,0.00075873145,0.00029163918,0.00009504968,0.00004713545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005032391,0.00017660348,0.00032346672,0.00020038491,0.00045114476,0.000023086475,0.0009926787,0.000020626938,0.00003259368],"category_scores_gemma":[0.0022541974,0.000099694895,0.0003146844,0.0010311109,0.00037325657,0.00020464043,0.00028340533,0.0005670727,0.0000010027308],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0053503187,0.008704708,0.93051994,0.0000045541174,0.0003139662,0.00007288934,0.013965708,0.029508969,0.009928958,0.00046308836,0.0003047834,0.0008621127],"study_design_scores_gemma":[0.0052570472,0.002597656,0.9687077,0.00002334776,0.000029471865,0.0000036993054,0.019866554,0.00023704352,0.0003970525,0.0027732246,0.0000059074127,0.00010132991],"about_ca_topic_score_codex":0.0017231794,"about_ca_topic_score_gemma":0.0017093946,"teacher_disagreement_score":0.03818772,"about_ca_system_score_codex":0.00015330604,"about_ca_system_score_gemma":0.00013553182,"threshold_uncertainty_score":0.40654397},"labels":[],"label_agreement":null},{"id":"W4213153102","doi":"10.1097/cco.0b013e32835cb881","title":"Editorial introductions","year":2012,"lang":"en","type":"article","venue":"Current Opinion in Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine","score_opus":0.08823617168613965,"score_gpt":0.39650937810231585,"score_spread":0.30827320641617617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213153102","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009789759,0.0007310447,0.00009385656,0.001157806,0.9855627,0.00016556939,0.0000052084088,0.000063754385,0.002430329],"genre_scores_gemma":[0.28731847,0.0013336549,0.00008948697,0.000153625,0.7108916,0.00010700881,0.000012072331,0.000017678558,0.00007640677],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99901426,0.00016683058,0.00016904583,0.0001981995,0.00012930037,0.0003223632],"domain_scores_gemma":[0.9995142,0.0002082669,0.000050154227,0.00013258164,0.000013332595,0.00008144477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016501515,0.000078644494,0.00010968044,0.00011840931,0.00005596802,0.0000072975604,0.00014369612,0.00008513359,0.00018916058],"category_scores_gemma":[0.0006903045,0.000075349606,0.000033315147,0.00026445024,0.00010841403,0.00017442516,0.000061528546,0.00026664042,0.00035556665],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026211246,0.0005977417,0.0010777204,0.000014330564,6.0027816e-7,2.2951442e-8,0.00038580463,0.0000063011294,0.0050606676,0.014678123,0.93693686,0.041215625],"study_design_scores_gemma":[0.0005457934,0.000058031044,0.002236748,0.00000716875,5.8795393e-7,0.0000051099287,0.00005469598,0.000009318264,0.00070309837,0.0006111824,0.9956854,0.00008287722],"about_ca_topic_score_codex":0.0000027562423,"about_ca_topic_score_gemma":0.0000011060158,"teacher_disagreement_score":0.27752873,"about_ca_system_score_codex":0.00010042621,"about_ca_system_score_gemma":0.000066650086,"threshold_uncertainty_score":0.45702085},"labels":[],"label_agreement":null},{"id":"W4220700883","doi":"10.1038/s41398-022-01900-6","title":"Developing symptom clusters: linking inflammatory biomarkers to depressive symptom profiles","year":2022,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Royal Ottawa Mental Health Centre; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Anhedonia; Depression (economics); Anxiety; Comorbidity; Clinical psychology; Atypical depression; Cluster (spacecraft); Medicine; Psychology; Psychiatry; Schizophrenia (object-oriented programming); Mood","score_opus":0.02407278673064288,"score_gpt":0.2724342329664518,"score_spread":0.2483614462358089,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220700883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96154904,0.00042910094,0.008624044,0.020884544,0.0024293545,0.0010513158,0.00013849512,0.00038668013,0.004507444],"genre_scores_gemma":[0.9846502,0.0000063376838,0.0068467213,0.007892403,0.00021471194,0.0001916429,0.00004203683,0.000049765866,0.00010618936],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.99779034,0.00018567363,0.00037177003,0.0005971491,0.00066798594,0.00038708665],"domain_scores_gemma":[0.99929273,0.00022181825,0.00011071859,0.0002288367,0.000026676473,0.00011919186],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017851272,0.00022265075,0.00015593805,0.00029735,0.00075666193,0.00006658941,0.00049148273,0.000060082977,0.00033814303],"category_scores_gemma":[0.000036900336,0.00024641957,0.0001242602,0.0006527597,0.00007473871,0.00022419136,0.00010099143,0.0002668406,0.000074270705],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021463337,0.0009739326,0.23799953,0.0008605323,0.00043181342,0.00007762221,0.016225874,0.056593984,0.14542364,0.48651025,0.020312801,0.032443695],"study_design_scores_gemma":[0.01764168,0.0008425172,0.5243009,0.0011734397,0.00017525846,0.0004441187,0.0077507617,0.013773184,0.055028636,0.19198067,0.17966358,0.007225269],"about_ca_topic_score_codex":0.0000052440023,"about_ca_topic_score_gemma":0.00002003037,"teacher_disagreement_score":0.2945296,"about_ca_system_score_codex":0.00006717073,"about_ca_system_score_gemma":0.00043551545,"threshold_uncertainty_score":0.9999988},"labels":[],"label_agreement":null},{"id":"W4220734344","doi":"10.1016/j.eatbeh.2022.101622","title":"Associations between psychosis symptoms and eating disorders among a national sample of U.S. college students","year":2022,"lang":"en","type":"article","venue":"Eating Behaviors","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Psychosis; Eating disorders; Psychology; Psychiatry; Confounding; Poisson regression; Clinical psychology; Medicine; Population; Internal medicine","score_opus":0.027357772260987522,"score_gpt":0.3141919193108728,"score_spread":0.2868341470498853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220734344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975907,0.000009536204,0.000025203344,0.000060902476,0.00011613838,0.00032371303,0.0013053218,0.00006671422,0.00050177134],"genre_scores_gemma":[0.9993116,0.0000027984722,0.0002854459,0.00008840598,0.000022385924,0.00010121407,0.00004531473,0.000022663704,0.0001201647],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99796313,0.00018094183,0.0003460181,0.00034807454,0.00092813966,0.00023369327],"domain_scores_gemma":[0.9987812,0.0007318469,0.0002805149,0.000116621304,0.00002866623,0.000061123814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033844486,0.00012911367,0.00019122551,0.0001652692,0.0007879177,0.000041002317,0.00030332743,0.00003847772,0.00013466137],"category_scores_gemma":[0.0007333005,0.00015050865,0.00007196702,0.0005884603,0.000121339835,0.00013282539,0.0002269595,0.00020870312,0.0000013365924],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002748832,0.00016555714,0.99442697,0.000004261359,0.000008079482,3.9279675e-7,0.0011554544,0.000058369264,0.002463598,0.00029583016,0.00012686374,0.0012918502],"study_design_scores_gemma":[0.00056748383,0.000111425725,0.99719375,0.000014750546,0.00001692956,5.125997e-7,0.0007398932,0.000058768735,0.0005429393,0.00052755326,0.00007093969,0.00015507283],"about_ca_topic_score_codex":0.00038734564,"about_ca_topic_score_gemma":0.0000786481,"teacher_disagreement_score":0.002766736,"about_ca_system_score_codex":0.00010033008,"about_ca_system_score_gemma":0.00003593353,"threshold_uncertainty_score":0.6137565},"labels":[],"label_agreement":null},{"id":"W4220746170","doi":"10.1139/cjc-2021-0324","title":"A privileged dual action Alzheimer's disease therapeutic platform targeting immunopathic and proteopathic mechanisms: (<i>E</i>)-3-styrylindoles as inhibitors of indoleamine 2,3-dioxygenase-mediated tryptophan metabolism and β-amyloid aggregation","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Krembil Foundation; University of Toronto; Compute Canada","keywords":"Chemistry; Neuroinflammation; Small molecule; Microglia; Biochemistry; Docking (animal); Indoleamine 2,3-dioxygenase; Tryptophan; Pharmacology; Amino acid; Inflammation; Immunology; Biology","score_opus":0.018007974792531283,"score_gpt":0.22474335230292183,"score_spread":0.20673537751039056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220746170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911007,0.007933524,0.000026560818,0.000288286,0.00020690574,0.00028811037,0.000098642864,0.000016033926,0.000041223786],"genre_scores_gemma":[0.9992991,0.00016773927,0.00004571737,0.000274106,0.00012147761,0.000023563216,0.000014786092,0.00003450213,0.000019012325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981782,0.00015169304,0.00056542363,0.00029713984,0.00045781335,0.0003497385],"domain_scores_gemma":[0.9983274,0.00012651486,0.0006792682,0.00015917575,0.00009571468,0.0006119276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053502846,0.00024052187,0.00032979037,0.00021031167,0.0004295241,0.00007187765,0.000223944,0.000097652366,0.00012603738],"category_scores_gemma":[0.00072837673,0.00024217772,0.000098876015,0.0003467794,0.00023305696,0.00031374497,0.000055545755,0.0006551093,7.623109e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022603138,0.000046113822,0.00011119516,0.00009538453,0.00003520817,0.00014269468,0.00088252116,0.000035751193,0.9945532,0.0000895065,0.000016900076,0.0037654815],"study_design_scores_gemma":[0.001528962,0.00012268667,0.0014801894,0.000098499135,0.000042237934,0.00041061474,0.0022034543,0.00015617524,0.9912905,0.0019884026,0.00042278023,0.00025546414],"about_ca_topic_score_codex":0.00015108651,"about_ca_topic_score_gemma":0.00006155663,"teacher_disagreement_score":0.008198383,"about_ca_system_score_codex":0.000088935005,"about_ca_system_score_gemma":0.0012207187,"threshold_uncertainty_score":0.9875721},"labels":[],"label_agreement":null},{"id":"W4220779406","doi":"10.1016/j.yfrne.2022.100989","title":"Sex differences in the blood–brain barrier: Implications for mental health","year":2022,"lang":"en","type":"review","venue":"Frontiers in Neuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada First Research Excellence Fund; Trinity College Dublin","keywords":"Context (archaeology); Schizophrenia (object-oriented programming); Major depressive disorder; Bipolar disorder; Mental health; Affect (linguistics); Psychiatry; Medicine; Psychology; Clinical psychology; Bioinformatics; Biology; Cognition","score_opus":0.08404217447304624,"score_gpt":0.3414025279948521,"score_spread":0.25736035352180586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220779406","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011036359,0.98157734,0.00007793137,0.011474963,0.0017031356,0.0037648287,0.000771651,0.00007998035,0.00043979828],"genre_scores_gemma":[0.00011942754,0.9906892,0.00016397446,0.005807031,0.000056997247,0.0025648575,0.000097560645,0.000057287478,0.0004436395],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.994961,0.0019785254,0.00078820693,0.0010889645,0.00018829943,0.0009949888],"domain_scores_gemma":[0.9974032,0.0014961215,0.00035246642,0.0006665608,0.000003941736,0.000077723555],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001331112,0.0004512304,0.0014137729,0.0006820316,0.00040010802,0.000049085284,0.0018340735,0.00007917999,0.000049445218],"category_scores_gemma":[0.0005256304,0.0003535491,0.0003445431,0.0008717415,0.00032378238,0.000067727415,0.00025882837,0.00096177857,0.000003738149],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018889685,0.000333993,0.0005012857,0.0012617931,0.000020894917,0.00005447584,0.00047800105,5.175612e-7,0.0000044303565,0.0057615624,0.066441685,0.92512244],"study_design_scores_gemma":[0.00059001165,0.00032174305,0.00013687182,0.00009703932,0.000020774056,0.00032758882,0.0002851792,0.0000069052935,0.0000027270776,0.001360896,0.9965902,0.00026006825],"about_ca_topic_score_codex":0.00002242734,"about_ca_topic_score_gemma":0.00004239611,"teacher_disagreement_score":0.9301485,"about_ca_system_score_codex":0.00013770912,"about_ca_system_score_gemma":0.00034249166,"threshold_uncertainty_score":0.99989164},"labels":[],"label_agreement":null},{"id":"W4220780633","doi":"10.1016/j.pnpbp.2022.110550","title":"N-acetyl cysteine (NAC) augmentation in the treatment of obsessive-compulsive disorder: A phase III, 20-week, double-blind, randomized, placebo-controlled trial","year":2022,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Health and Medical Research Council","keywords":"Placebo; Randomized controlled trial; Adjunctive treatment; Anxiety; Obsessive compulsive; Medicine; Adverse effect; Internal medicine; Clinical trial; Clinical Global Impression; Psychiatry; Psychology","score_opus":0.044814317356078034,"score_gpt":0.35954659106877307,"score_spread":0.314732273712695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220780633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9771491,0.004320655,0.000011584568,0.004233695,0.002672542,0.011235313,0.000040376028,0.000051146784,0.00028556574],"genre_scores_gemma":[0.9868185,0.0017832393,0.00004889022,0.0021494033,0.0001825731,0.008934108,0.000032037682,0.000016579437,0.00003465818],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.994205,0.0030203173,0.0010475175,0.00090770517,0.00030295,0.00051652023],"domain_scores_gemma":[0.99688834,0.0022043386,0.00056343066,0.00024098284,0.000019438685,0.00008348373],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00079511956,0.00041542645,0.0011404913,0.00030917223,0.00034390765,0.000034286346,0.000555021,0.000158604,0.00026783123],"category_scores_gemma":[0.00008801467,0.00025176012,0.00033555907,0.00074463955,0.00092985417,0.00009006719,0.0000950004,0.000539516,0.0000027881456],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.97075194,0.015845424,0.0054178475,0.000016310467,0.000055985467,0.00006537926,0.0007484991,0.00008821423,0.00083338865,0.0008461953,0.00015002444,0.0051807864],"study_design_scores_gemma":[0.98277044,0.01306851,0.00049091066,0.000007710318,0.000068484194,0.00003449067,0.0005964893,0.0005703975,0.000084477164,0.0012369732,0.00081391144,0.0002572053],"about_ca_topic_score_codex":0.000010635676,"about_ca_topic_score_gemma":0.000021573947,"teacher_disagreement_score":0.012018493,"about_ca_system_score_codex":0.000045158708,"about_ca_system_score_gemma":0.000080098354,"threshold_uncertainty_score":0.99999344},"labels":[],"label_agreement":null},{"id":"W4220794838","doi":"10.1503/jpn.210121","title":"TGF-β1 is associated with deficits in cognition and cerebral cortical thickness in first-episode schizophrenia","year":2022,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Beijing Municipal Administration of Hospitals; Eesti Teadusagentuur; National Natural Science Foundation of China; European Commission","keywords":"Schizophrenia (object-oriented programming); Cognition; Prefrontal cortex; Internal medicine; Psychology; Neuroimaging; Biomarker; Neuroscience; Effects of sleep deprivation on cognitive performance; Transcriptome; Medicine; Psychiatry; Biology; Gene expression; Gene","score_opus":0.01985008811633356,"score_gpt":0.2493046325693998,"score_spread":0.22945454445306623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220794838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995613,0.00014244503,0.000033632947,0.0034265844,0.00052351755,0.00012409239,0.000013744265,0.000009431441,0.000113565315],"genre_scores_gemma":[0.99677724,0.00007839559,0.0000741825,0.003018595,0.000021933532,0.0000049576206,2.1466937e-7,0.000009511853,0.000014961747],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99825454,0.0002686711,0.00036147845,0.00034825754,0.00047882213,0.00028824888],"domain_scores_gemma":[0.99932885,0.00020427989,0.00024913848,0.00008387991,0.000021227534,0.00011264566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046334168,0.00013453577,0.00021203373,0.00027773314,0.0003650192,0.00007698919,0.00023987037,0.00004066382,0.000020884498],"category_scores_gemma":[0.00049264624,0.00011395184,0.000033021122,0.00095519907,0.00024964468,0.00037735156,0.00009594158,0.0007171278,4.3808691e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036665536,0.0031075964,0.86565477,0.00012513327,0.00000606104,0.0009979592,0.0024845006,0.0017296692,0.11359715,0.0067560785,0.0005898869,0.0012846673],"study_design_scores_gemma":[0.0058997977,0.0018837379,0.97729456,0.00018747026,0.00001724619,0.0017178771,0.0008469484,0.0029368466,0.0029391635,0.0058062538,0.00011653861,0.0003535843],"about_ca_topic_score_codex":0.000009636002,"about_ca_topic_score_gemma":0.00030712213,"teacher_disagreement_score":0.11163979,"about_ca_system_score_codex":0.000024249202,"about_ca_system_score_gemma":0.00010394811,"threshold_uncertainty_score":0.46468213},"labels":[],"label_agreement":null},{"id":"W4220810564","doi":"10.1016/j.jad.2022.03.043","title":"Recurrent depression has persistent effects on cognition but this does not appear to be mediated by neuroinflammation","year":2022,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"Medical Research Council; National Institute for Health and Care Research","keywords":"Neuroinflammation; Depression (economics); Cognition; Psychology; Neuroscience; Medicine; Clinical psychology; Internal medicine; Inflammation","score_opus":0.01698447060646402,"score_gpt":0.24677904266021394,"score_spread":0.22979457205374992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220810564","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990498,0.000108753185,0.0001671122,0.006411066,0.0011215837,0.0007771936,0.000075490934,0.00004623268,0.00079458155],"genre_scores_gemma":[0.99690753,0.00008870092,0.000014536656,0.0027275642,0.000061087776,0.000054422773,0.000012771287,0.000032029784,0.00010134462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99721843,0.0008080995,0.00032687656,0.00037998296,0.00096536294,0.00030124973],"domain_scores_gemma":[0.9981638,0.0010177864,0.0004091276,0.0001542553,0.000076386146,0.00017860805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032947696,0.00023230986,0.0002603037,0.00035823707,0.0005583031,0.00008065338,0.0003059467,0.000050359035,0.00019648403],"category_scores_gemma":[0.0020364572,0.00018133523,0.0002679573,0.00046967444,0.00007635581,0.00024580437,0.00011084068,0.0005536458,0.00002597281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016571844,0.00066940184,0.0001724524,0.00004906739,0.00003928246,0.000027467342,0.002099854,0.0007762108,0.92655843,0.000028074439,0.01064251,0.05728007],"study_design_scores_gemma":[0.0056335665,0.007887606,0.0044648997,0.00016811214,0.00009569189,0.000054751486,0.003342554,0.0008244466,0.9575868,0.00034111974,0.01898587,0.00061453256],"about_ca_topic_score_codex":0.0000146033635,"about_ca_topic_score_gemma":0.000018208148,"teacher_disagreement_score":0.056665536,"about_ca_system_score_codex":0.00017389812,"about_ca_system_score_gemma":0.00006314919,"threshold_uncertainty_score":0.73946357},"labels":[],"label_agreement":null},{"id":"W4220850669","doi":"10.1101/2022.03.30.22273201","title":"A Sex-Specific Genome-Wide Association Study of Depression Phenotypes in UK Biobank","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Medical Research Council; Hope for Depression Research Foundation","keywords":"Genome-wide association study; Depression (economics); Biobank; Genetic association; Biology; Waist; Medicine; Genetics; Gene; Internal medicine; Single-nucleotide polymorphism; Genotype; Body mass index","score_opus":0.03391031678457402,"score_gpt":0.27165885592251077,"score_spread":0.23774853913793675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220850669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956719,0.0003857617,0.000024062761,0.00013272799,0.0007000871,0.0008666429,0.00003202414,0.00007334708,0.0021134089],"genre_scores_gemma":[0.99875784,0.00020993955,0.000029801911,0.0001682469,0.0000491616,0.00014258327,0.000012347222,0.000034199973,0.00059585075],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9969063,0.0006554413,0.0005116178,0.00086567336,0.00074920006,0.0003117774],"domain_scores_gemma":[0.9981666,0.0006478818,0.00046761925,0.0006469367,0.000021313042,0.000049634065],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006177335,0.0002486742,0.000432425,0.00034386656,0.0001052122,0.00004579005,0.00074557244,0.00016129669,0.0005527609],"category_scores_gemma":[0.0009289973,0.00024814764,0.00010259549,0.0005011476,0.00003413431,0.000046701236,0.00096843205,0.0007330494,0.000022030494],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005331531,0.0008622651,0.9641469,0.000040721145,0.000011874198,0.000028570796,0.003731073,0.0009618921,0.029119631,0.000014674161,0.00022705618,0.00080202584],"study_design_scores_gemma":[0.0010153999,0.000109761524,0.97858536,0.000029060358,0.000009224916,2.662386e-7,0.0011635937,0.000054861317,0.014335542,0.00087351317,0.0035149665,0.00030843515],"about_ca_topic_score_codex":0.000112927206,"about_ca_topic_score_gemma":0.00013357439,"teacher_disagreement_score":0.014784089,"about_ca_system_score_codex":0.00024452235,"about_ca_system_score_gemma":0.000065030625,"threshold_uncertainty_score":0.9999971},"labels":[],"label_agreement":null},{"id":"W4220857812","doi":"10.3389/fped.2022.837741","title":"Associations Between Eczema and Attention Deficit Hyperactivity Disorder Symptoms in Children","year":2022,"lang":"en","type":"article","venue":"Frontiers in Pediatrics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Medical Research Council; Medical Research Council; National Research Foundation Singapore; National University Health System; National Research Foundation","keywords":"Medicine; Attention deficit hyperactivity disorder; Microbiome; Cord blood; Allergy; Immunology; Pediatrics; Psychiatry; Bioinformatics","score_opus":0.009696496484477995,"score_gpt":0.23048128399202608,"score_spread":0.2207847875075481,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220857812","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975938,0.00034547487,0.000587904,0.00023067699,0.00040263604,0.00032024775,0.00024692848,0.000044008062,0.0002282801],"genre_scores_gemma":[0.9992127,0.00017884353,0.00023417413,0.00009435914,0.00007271156,0.000035768928,0.00005483163,0.0000184723,0.00009814657],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984752,0.00025138073,0.00024614917,0.00039887178,0.00032236232,0.00030605882],"domain_scores_gemma":[0.99949795,0.0001827127,0.000121504214,0.0001416841,0.000007702949,0.000048453185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027921537,0.00012621624,0.00020803443,0.00045144433,0.00026675247,0.000038651913,0.00019936485,0.000066155124,0.000016619813],"category_scores_gemma":[0.00039337395,0.00015066739,0.00004698048,0.0011336174,0.000048005244,0.0002204809,0.00017289542,0.00040924,0.0000035188898],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005826041,0.00013147327,0.99467194,0.0000031369639,0.0000026160908,0.0000022782283,0.000078692654,0.0002012342,0.0000392584,0.00007119829,0.00046878716,0.0043235375],"study_design_scores_gemma":[0.0008774993,0.000035793808,0.9975373,9.140712e-7,0.000011806649,0.0000019805711,0.00017950697,0.00030133815,0.0000069839134,0.0007300073,0.00014271322,0.00017416338],"about_ca_topic_score_codex":0.000109900895,"about_ca_topic_score_gemma":0.000026447357,"teacher_disagreement_score":0.004149374,"about_ca_system_score_codex":0.00018276928,"about_ca_system_score_gemma":0.000043627533,"threshold_uncertainty_score":0.6144038},"labels":[],"label_agreement":null},{"id":"W4220863413","doi":"10.20944/preprints202203.0136.v1","title":"Impact of Maternal Immune Activation Early in Pregnancy on Brain Development of Offspring: A Combined Morphological, Spectroscopic, and Behavioral Study","year":2022,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Hospital; McGill University; Douglas Mental Health University Institute; Sunnybrook Health Science Centre","funders":"","keywords":"Offspring; Pregnancy; Psychology; Open field; Prepulse inhibition; Endocrinology; Caudate nucleus; Internal medicine; Hippocampus; Schizophrenia (object-oriented programming); Physiology; Medicine; Biology; Psychiatry","score_opus":0.1407949851547916,"score_gpt":0.38415988308006566,"score_spread":0.24336489792527405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220863413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977332,0.000013267713,0.000007920371,0.000041743206,0.00011834307,0.0016852295,0.000015316145,0.000051325496,0.0003336573],"genre_scores_gemma":[0.9994798,0.000015015782,0.0000814056,0.000013453374,0.000005528726,0.00023633779,0.0000071840964,0.000029001087,0.00013228593],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99703133,0.000359745,0.00083550625,0.00094438356,0.00051344966,0.0003155999],"domain_scores_gemma":[0.99838847,0.00015877825,0.00062335446,0.0007303381,0.000032089454,0.00006697215],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037591098,0.0003473914,0.0006110036,0.00035130803,0.000079529105,0.000019429992,0.00066581194,0.00013883335,0.00079966476],"category_scores_gemma":[0.00032007147,0.0003293296,0.00014050391,0.00024919276,0.00013425818,0.000085444546,0.0019631889,0.0007562456,0.000013663231],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031389858,0.002103882,0.5837587,0.000054559987,0.000018796325,0.00001969899,0.0026725845,0.00007903941,0.4106716,0.00002750544,4.3298007e-7,0.0002793161],"study_design_scores_gemma":[0.0010945438,0.0004962404,0.6497327,0.00018736697,0.000005236152,0.0000010419951,0.00012591845,0.000006413855,0.3480492,0.00014019189,0.0000011880655,0.00015996718],"about_ca_topic_score_codex":0.000650692,"about_ca_topic_score_gemma":0.000014411496,"teacher_disagreement_score":0.06597401,"about_ca_system_score_codex":0.00023141237,"about_ca_system_score_gemma":0.00020169796,"threshold_uncertainty_score":0.9999159},"labels":[],"label_agreement":null},{"id":"W4220952985","doi":"10.1111/apt.16875","title":"Editorial: some of the obstacles in managing mood disorders in <scp>IBD</scp>","year":2022,"lang":"en","type":"editorial","venue":"Alimentary Pharmacology & Therapeutics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Manitoba","funders":"","keywords":"Medicine; Mood; Mood disorders; Psychiatry; Anxiety","score_opus":0.016513892359135952,"score_gpt":0.29238044119054707,"score_spread":0.2758665488314111,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220952985","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.041724492,0.0012223733,4.1810836e-7,0.0013317019,0.95376325,0.0010198653,0.0002789053,0.00006439586,0.0005946083],"genre_scores_gemma":[0.06941681,0.013498843,0.000015107655,0.0061884234,0.9097062,0.00036461608,0.00012307342,0.00021009037,0.00047688198],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99510926,0.0012557181,0.0007639345,0.000905531,0.001118439,0.00084712415],"domain_scores_gemma":[0.994683,0.0042424332,0.0004869907,0.00049376424,0.000026068667,0.00006774426],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000503891,0.00054883544,0.0006187715,0.00044216757,0.00021598309,0.00003225925,0.0019621504,0.00051912555,0.00020383006],"category_scores_gemma":[0.00002369181,0.0005078425,0.00024453417,0.0008794054,0.0005407075,0.00024550906,0.00077558926,0.0023327742,0.000009885188],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001306803,0.0010115383,0.00069347693,0.00009669395,0.00053626066,0.000010926694,0.0018920122,0.00050904736,0.066816874,0.00006106051,0.92786586,0.00037557987],"study_design_scores_gemma":[0.0039098137,0.00019401989,0.00022712773,0.000036489757,0.0005788066,8.4192766e-7,0.001241673,0.00012110317,0.027780669,0.0029025043,0.962756,0.00025094918],"about_ca_topic_score_codex":0.00029225004,"about_ca_topic_score_gemma":0.0005157765,"teacher_disagreement_score":0.04405709,"about_ca_system_score_codex":0.00038552986,"about_ca_system_score_gemma":0.00037083201,"threshold_uncertainty_score":0.9999689},"labels":[],"label_agreement":null},{"id":"W4220955147","doi":"10.3390/ijms23063259","title":"Microbe-Immune Crosstalk: Evidence That T Cells Influence the Development of the Brain Metabolome","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; St. Michael's Hospital; McMaster University","funders":"NIHR Imperial Biomedical Research Centre; Biotechnology and Biological Sciences Research Council; McMaster University; Ontario Brain Institute; Medical Research Council; National Institute for Health and Care Research","keywords":"Metabolome; Immune system; Crosstalk; Biology; Computational biology; Neuroscience; Cell biology; Metabolomics; Immunology; Bioinformatics","score_opus":0.03350897464022835,"score_gpt":0.29674374651100105,"score_spread":0.2632347718707727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220955147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99058825,0.0010939855,0.00082848687,0.006186,0.0010114772,0.00010235558,0.000005778496,0.0000043094187,0.00017933709],"genre_scores_gemma":[0.99667335,0.000025473546,0.0006755321,0.002493441,0.000015310812,0.000004632712,6.460504e-8,0.0000047672875,0.00010743855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997003,0.00033263446,0.00045407464,0.00018820919,0.0018487236,0.00017335606],"domain_scores_gemma":[0.9983644,0.00046004297,0.00083159725,0.00016622254,0.00014512222,0.000032616244],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015827838,0.00009917112,0.00012103307,0.00014023237,0.000511504,0.00014240468,0.0037002063,0.000014574723,0.0000936649],"category_scores_gemma":[0.00091683265,0.000056314075,0.0001659623,0.0005325935,0.00074996037,0.0003325529,0.00071587303,0.00024993074,0.0000032996236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023657005,0.000050221326,0.00035940285,0.0000019771192,0.000014259812,0.000016660224,0.0014919352,0.005641101,0.98952067,0.0008002918,0.000071541544,0.00200826],"study_design_scores_gemma":[0.00019271222,0.000051048897,0.0075959703,0.000042149386,0.000004041285,0.00013993954,0.000751634,0.000052814295,0.98457897,0.000743508,0.005772108,0.0000751282],"about_ca_topic_score_codex":0.000009932462,"about_ca_topic_score_gemma":0.0000042688525,"teacher_disagreement_score":0.007236568,"about_ca_system_score_codex":0.00005894985,"about_ca_system_score_gemma":0.00051566225,"threshold_uncertainty_score":0.68759656},"labels":[],"label_agreement":null},{"id":"W4221008667","doi":"10.1002/pmic.202100244","title":"Antidepressant treatment effects on hippocampal protein turnover: Molecular and spatial insights from mass spectrometry","year":2022,"lang":"en","type":"article","venue":"PROTEOMICS","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"Deutsche Forschungsgemeinschaft; Max-Planck-Gesellschaft; European Molecular Biology Organization","keywords":"Antidepressant; Paroxetine; Hippocampal formation; Mass spectrometry imaging; Chemistry; Mode of action; Pharmacology; Protein turnover; Mass spectrometry; Hippocampus; Neuroscience; Biochemistry; Biology; Protein biosynthesis; Chromatography","score_opus":0.009791883031808423,"score_gpt":0.21836282327839107,"score_spread":0.20857094024658265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221008667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99476326,0.00017309732,0.002159952,0.00024458684,0.00018011834,0.0018057529,0.000063392436,0.000094076764,0.00051579706],"genre_scores_gemma":[0.9974931,0.000013764866,0.0014488735,0.00041632785,0.00007977611,0.00044439646,0.000010065995,0.0000360872,0.000057593756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830836,0.0002604721,0.00016025793,0.0006241531,0.00036419177,0.00028258524],"domain_scores_gemma":[0.9993463,0.00012988137,0.00009476275,0.00032362214,0.0000060761413,0.00009936942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000417319,0.00024062906,0.0002271321,0.00012818722,0.0002625622,0.000073708296,0.00021748432,0.000049307586,0.00006736568],"category_scores_gemma":[0.00012817995,0.00021325648,0.000074101765,0.00021488909,0.00006470381,0.000064293425,0.00014455093,0.0002487632,0.000019824824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002525625,0.00021218401,0.00025363668,0.000014593129,0.000013541138,0.00020759464,0.00018764233,0.000058156147,0.99410284,0.00094915944,0.000008415656,0.0037396776],"study_design_scores_gemma":[0.0017622833,0.0011277052,0.0016840287,0.000014540924,0.000008245247,0.0000069637913,0.000029177794,0.0006584346,0.9834491,0.010665832,0.00034807614,0.0002456113],"about_ca_topic_score_codex":0.00020015161,"about_ca_topic_score_gemma":0.000010650109,"teacher_disagreement_score":0.010653735,"about_ca_system_score_codex":0.00014888028,"about_ca_system_score_gemma":0.000047410133,"threshold_uncertainty_score":0.8696347},"labels":[],"label_agreement":null},{"id":"W4221064290","doi":"10.1016/j.bbi.2022.03.013","title":"Machine learning based prediction and the influence of complement – Coagulation pathway proteins on clinical outcome: Results from the NEURAPRO trial","year":2022,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Regional Development Fund; National Health and Medical Research Council; Science Foundation Ireland; University College Dublin; Health Service Executive; Wellcome Trust; Canadian Institute for Theoretical Astrophysics","keywords":"Outcome (game theory); Complement (music); Coagulation; Complement system; Medicine; Artificial intelligence; Computer science; Computational biology; Machine learning; Bioinformatics; Internal medicine; Chemistry; Immunology; Biology; Biochemistry; Phenotype; Mathematics","score_opus":0.098294110086618,"score_gpt":0.33899071499890016,"score_spread":0.24069660491228217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221064290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960291,0.000019753004,0.000015995502,0.0017127667,0.00013317552,0.0015257797,0.0004973874,0.00003238283,0.000033705765],"genre_scores_gemma":[0.99868745,0.000010535147,0.000012054918,0.0009949049,0.000023130915,0.00015522615,0.00007117745,0.000008173093,0.0000373218],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99628365,0.0025089826,0.0005157898,0.00024941456,0.0003225719,0.00011956569],"domain_scores_gemma":[0.9964554,0.0029022044,0.0002701544,0.0003212266,0.000019321342,0.00003170113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019081174,0.000110010325,0.00017807371,0.000031948308,0.0009555502,0.000040569903,0.00022964922,0.00003277263,0.000028078717],"category_scores_gemma":[0.0024321564,0.00006780387,0.00006795756,0.00015185711,0.00041363738,0.00006280697,0.00019239292,0.0006253283,4.2826332e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.2122569,0.0052626845,0.45721874,0.000037384736,0.00004301996,0.000017867433,0.010240559,0.009569577,0.19398756,0.0032465195,0.00049853994,0.107620664],"study_design_scores_gemma":[0.04053522,0.0014259958,0.9517073,0.000008676198,0.000020322886,0.000001603706,0.00034415367,0.0028390102,0.0013727125,0.00007907824,0.0015749759,0.00009097696],"about_ca_topic_score_codex":0.00077323767,"about_ca_topic_score_gemma":0.000034211083,"teacher_disagreement_score":0.49448854,"about_ca_system_score_codex":0.000012920918,"about_ca_system_score_gemma":0.000030795563,"threshold_uncertainty_score":0.7349416},"labels":[],"label_agreement":null},{"id":"W4223496916","doi":"10.3389/fpsyt.2022.859772","title":"Inflammatory Blood Biomarker Kynurenine Is Linked With Elevated Neuroinflammation and Neurodegeneration in Older Adults: Evidence From Two 1H-MRS Post-Processing Analysis Methods","year":2022,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Lietuvos Mokslo Taryba","keywords":"Neuroinflammation; Neurodegeneration; Dorsolateral prefrontal cortex; Medicine; Cognitive decline; Posterior cingulate; Kynurenine pathway; Internal medicine; Anterior cingulate cortex; Montreal Cognitive Assessment; Psychology; Kynurenine; Neuroscience; Functional magnetic resonance imaging; Endocrinology; Inflammation; Cognition; Prefrontal cortex; Dementia; Biology; Disease","score_opus":0.011893044752761072,"score_gpt":0.2738449290190147,"score_spread":0.2619518842662536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223496916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9844831,0.0021499314,0.009444625,0.0019779496,0.0012975988,0.00049629546,0.00003376174,0.00009572722,0.000020993306],"genre_scores_gemma":[0.95885336,0.00012355208,0.03920216,0.0015420277,0.000064236796,0.00008894672,0.00004908831,0.00004589449,0.000030746094],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9965297,0.00096980215,0.00059614354,0.0010425465,0.00046121408,0.00040058652],"domain_scores_gemma":[0.99894977,0.00014317642,0.00033163815,0.00042733902,0.00005058193,0.000097476535],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00051583536,0.00030832924,0.00038236272,0.0011213564,0.00027381149,0.00012368841,0.00036203008,0.00008720715,0.00009111761],"category_scores_gemma":[0.00025255184,0.00030941083,0.00008815475,0.00315016,0.00012780649,0.0006182252,0.0001261275,0.0005036515,0.0000010728094],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016673694,0.00031964653,0.8195273,0.00011434165,0.0001079616,0.00005234828,0.00467732,0.0064718784,0.13722368,0.00003320834,0.0010789218,0.028725998],"study_design_scores_gemma":[0.004928963,0.00018578101,0.78502995,0.00018687658,0.00024514023,0.00001345548,0.0017279807,0.19597282,0.010479765,0.00053491374,0.0000814056,0.0006129637],"about_ca_topic_score_codex":0.00018865467,"about_ca_topic_score_gemma":0.00053936336,"teacher_disagreement_score":0.18950094,"about_ca_system_score_codex":0.00006203491,"about_ca_system_score_gemma":0.00017675881,"threshold_uncertainty_score":0.9999358},"labels":[],"label_agreement":null},{"id":"W4223532225","doi":"10.1038/s41380-022-01550-6","title":"Adaptive changes to oxidative stress in schizophrenia","year":2022,"lang":"en","type":"letter","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Western University","funders":"","keywords":"Schizophrenia (object-oriented programming); Oxidative stress; Psychology; Neuroscience; Psychiatry; Cognitive psychology; Medicine; Internal medicine","score_opus":0.018328582775391938,"score_gpt":0.25052572824244157,"score_spread":0.23219714546704964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223532225","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03738657,0.00075445604,0.00024253735,0.9495244,0.0034409503,0.0014649415,0.00072087644,0.00020603082,0.0062592123],"genre_scores_gemma":[0.015040135,0.000025070905,0.0011298792,0.9815372,0.00085305213,0.00042594393,0.00011273638,0.00013396666,0.0007420044],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963354,0.0005389212,0.00028678178,0.0013335046,0.0007729754,0.0007324167],"domain_scores_gemma":[0.99885875,0.000097972195,0.00016831279,0.00075370667,0.000018977513,0.00010230876],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00009168514,0.00053015066,0.00044157612,0.0007208825,0.00014289946,0.00007782191,0.001092635,0.00033159243,0.0007490911],"category_scores_gemma":[0.00012253926,0.0005797344,0.00017816751,0.0010969592,0.00009490411,0.00005877682,0.00039859052,0.0023184998,0.00018861155],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025254994,0.00019909095,0.00003150728,0.00009985213,0.000029431965,0.0016938855,0.00038207762,0.00012118323,0.012756608,0.0014193238,0.98148,0.0015344934],"study_design_scores_gemma":[0.0019814784,0.0010166351,0.00016014803,0.0002892388,0.0000318408,0.000044661272,0.00056447426,0.000035251105,0.048122954,0.0051661734,0.94072783,0.0018593299],"about_ca_topic_score_codex":0.00007903107,"about_ca_topic_score_gemma":0.0003482567,"teacher_disagreement_score":0.04075218,"about_ca_system_score_codex":0.00011863496,"about_ca_system_score_gemma":0.00020216052,"threshold_uncertainty_score":0.9999832},"labels":[],"label_agreement":null},{"id":"W4224285954","doi":"10.3390/nu14091708","title":"Plasma Kynurenine to Tryptophan Ratio Is Not Associated with Undernutrition in Adults but Reduced after Nutrition Intervention: Results from a Community-Based Study in Bangladesh","year":2022,"lang":"en","type":"article","venue":"Nutrients","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"International Centre for Diarrhoeal Disease Research, Bangladesh; Styrelsen för Internationellt Utvecklingssamarbete; Global Affairs Canada; Department for International Development; Bill and Melinda Gates Foundation","keywords":"Interquartile range; Kynurenine; Malnutrition; Medicine; Internal medicine; Tryptophan; Endocrinology; Gastroenterology; Chemistry; Biochemistry; Amino acid","score_opus":0.03327056488890061,"score_gpt":0.2699093492798833,"score_spread":0.23663878439098268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224285954","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99501324,0.000009058931,0.00002217166,0.0013111096,0.00018739633,0.0020828648,0.0012114547,0.000093478135,0.00006921506],"genre_scores_gemma":[0.99630994,0.0000021849235,0.000052292096,0.0015328112,0.000028499353,0.0013277314,0.0006131118,0.00003576977,0.000097680866],"study_design_codex":"randomized_trial","study_design_gemma":"observational","domain_scores_codex":[0.99579805,0.0017191754,0.0006496405,0.00068182475,0.00075689075,0.00039439593],"domain_scores_gemma":[0.99870336,0.00043977867,0.00021544937,0.00047021537,0.0000608443,0.00011037411],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046756008,0.00026829186,0.00032893606,0.0005943413,0.0002978005,0.00008298727,0.00045785037,0.00008994166,0.00014577528],"category_scores_gemma":[0.00043869816,0.00029497163,0.000084344814,0.0017780412,0.000050189894,0.00022943012,0.00017184534,0.0007629286,0.000018103829],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.3072698,0.2529058,0.15928008,0.0005176291,0.00017203427,0.0020797614,0.1332576,0.0018902903,0.13097613,0.00011150914,0.0068555884,0.004683791],"study_design_scores_gemma":[0.16713285,0.008234683,0.6039269,0.0021349078,0.00003138152,0.0000049028476,0.016266355,0.0020513155,0.19787574,0.000706756,0.00050327607,0.0011309054],"about_ca_topic_score_codex":0.00077575847,"about_ca_topic_score_gemma":0.002927151,"teacher_disagreement_score":0.44464684,"about_ca_system_score_codex":0.00051924196,"about_ca_system_score_gemma":0.000050882416,"threshold_uncertainty_score":0.99995023},"labels":[],"label_agreement":null},{"id":"W4224323872","doi":"10.1016/j.genhosppsych.2022.04.005","title":"Depressive symptom trajectories and polygenic risk scores in individuals with an immune-mediated inflammatory disease","year":2022,"lang":"en","type":"article","venue":"General Hospital Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Government of Manitoba; University of Manitoba","funders":"National Institute of Mental Health","keywords":"Body mass index; Depression (economics); Major depressive disorder; Mediation; Depressive symptoms; Medicine; Anxiety; Disease; Clinical psychology; Demography; Internal medicine; Polygenic risk score; Psychology; Psychiatry; Single-nucleotide polymorphism; Genotype; Mood; Biology; Genetics","score_opus":0.005018179784081101,"score_gpt":0.21454299117009953,"score_spread":0.20952481138601844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224323872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954206,0.0023889174,0.0000041119556,0.00035653578,0.0007940186,0.00048658627,0.0003474255,0.00012838966,0.0000734266],"genre_scores_gemma":[0.9987452,0.000109747256,0.00018406952,0.0004970144,0.0001383738,0.00017492301,0.000044268287,0.000046569505,0.00005981382],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9978384,0.0003010789,0.00029118903,0.00068493455,0.00043455546,0.0004498708],"domain_scores_gemma":[0.9991117,0.00006591591,0.00018379629,0.00038270195,0.0000120938885,0.00024379652],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011826645,0.00027555026,0.00021402084,0.00020426746,0.00045251343,0.00008883527,0.00040471627,0.00004904728,0.00008048472],"category_scores_gemma":[0.00008370663,0.00025032205,0.00006553666,0.00047586867,0.00025007155,0.00038714724,0.0002032608,0.00040112674,0.000006352831],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022066802,0.00037323518,0.9944802,0.000020196847,0.000017348908,0.00003282669,0.0010285367,0.00045250298,0.0015136754,0.001218391,0.00017517232,0.00046723068],"study_design_scores_gemma":[0.0021051546,0.0006432588,0.99218035,0.0000151574695,0.000018248935,0.0000074976074,0.00086184987,0.0002022121,0.0005457343,0.0028740335,0.00010429694,0.0004422185],"about_ca_topic_score_codex":0.000113010006,"about_ca_topic_score_gemma":0.00011164931,"teacher_disagreement_score":0.0033246323,"about_ca_system_score_codex":0.000033636232,"about_ca_system_score_gemma":0.00022527087,"threshold_uncertainty_score":0.9999949},"labels":[],"label_agreement":null},{"id":"W4224981953","doi":"10.1016/j.biopsych.2022.02.493","title":"P257. Genetic Risk for Depression, Aging, and Effects on Inflammatory Biomarkers","year":2022,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Depression (economics); Polygenic risk score; White blood cell; Medicine; Inflammation; Internal medicine; Psychology; Biology; Genotype; Genetics; Gene; Single-nucleotide polymorphism","score_opus":0.01611112896760602,"score_gpt":0.2547210748908253,"score_spread":0.23860994592321927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224981953","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960735,0.0010856811,0.00011088162,0.00051768863,0.0010861174,0.0005179677,0.000038855294,0.00012596049,0.0004433419],"genre_scores_gemma":[0.99465305,0.00009920745,0.00074223743,0.0041195117,0.00013249033,0.00019273008,0.0000034198558,0.000013914511,0.00004345919],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99860746,0.00029819546,0.0001574066,0.0005373521,0.00012900143,0.0002705595],"domain_scores_gemma":[0.9991016,0.0005069666,0.000096090494,0.00019710857,0.000004838812,0.00009339422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015078913,0.0001503128,0.00012751488,0.00006683688,0.00051357085,0.000020869742,0.00023595363,0.000069544985,0.00007097877],"category_scores_gemma":[0.00032024717,0.00011051597,0.00008576216,0.00013368325,0.0001134399,0.00002066309,0.00014416571,0.0001833404,0.000012212137],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010431587,0.0005132728,0.78473574,0.00013049206,0.000035584326,0.000017817016,0.00012424098,0.00007596909,0.09120541,0.0042322986,0.040543493,0.07734251],"study_design_scores_gemma":[0.0027072595,0.0015211055,0.9118144,0.000023137256,0.000013677843,0.000021911237,0.0001368266,0.00022698872,0.00853601,0.022626929,0.051888462,0.0004832799],"about_ca_topic_score_codex":0.0000024065728,"about_ca_topic_score_gemma":0.0000014349484,"teacher_disagreement_score":0.12707865,"about_ca_system_score_codex":0.000014380016,"about_ca_system_score_gemma":0.000022801343,"threshold_uncertainty_score":0.45067105},"labels":[],"label_agreement":null},{"id":"W4225001182","doi":"10.1016/j.biopsych.2022.02.929","title":"P692. Systemic Inflammation Positively Correlates With High Suicide Ideation in Clood and CNS","year":2022,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"","keywords":"Suicidal ideation; Systemic inflammation; Inflammation; Gene; Gene expression; Biology; Neuroscience; Psychology; Immunology; Medicine; Poison control; Suicide prevention; Genetics; Environmental health","score_opus":0.01871465488455681,"score_gpt":0.23570111510890565,"score_spread":0.21698646022434884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225001182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973813,0.00027695316,0.00007107002,0.0011052951,0.00028064,0.00031363833,0.000022098257,0.000080408834,0.00046854836],"genre_scores_gemma":[0.99907297,0.000038431426,0.000138734,0.0005865167,0.000044161505,0.000054372267,0.000018384679,0.000007391331,0.000039062663],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99890625,0.00023230778,0.00019596248,0.0003490974,0.00013394855,0.00018245574],"domain_scores_gemma":[0.9996272,0.00013365968,0.00009757891,0.000093795104,0.000008564643,0.000039221137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013397133,0.00011510571,0.00013099755,0.000083803374,0.00017589697,0.000024386805,0.00012456352,0.00006451288,0.000055545075],"category_scores_gemma":[0.000080509904,0.00008383007,0.000022898172,0.0002990365,0.00008478672,0.000079647536,0.00006788481,0.00020462775,0.000011164681],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006101516,0.00022246636,0.6876121,0.000036326208,0.0000073931137,0.000020214442,0.00030067586,0.000532765,0.24423318,0.06432598,0.00016590032,0.0019328328],"study_design_scores_gemma":[0.0017168588,0.0010011237,0.98498154,0.000053261352,0.000005965986,0.00014448474,0.00090752955,0.0002347827,0.0027463932,0.0077946265,0.0001233127,0.00029014004],"about_ca_topic_score_codex":0.00003415038,"about_ca_topic_score_gemma":0.000028807057,"teacher_disagreement_score":0.29736942,"about_ca_system_score_codex":0.000034941077,"about_ca_system_score_gemma":0.000030740175,"threshold_uncertainty_score":0.34184912},"labels":[],"label_agreement":null},{"id":"W4225014396","doi":"10.1038/s41398-022-01932-y","title":"Correction: Developing symptom clusters: linking inflammatory biomarkers to depressive symptom profiles","year":2022,"lang":"en","type":"erratum","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Royal Ottawa Mental Health Centre; University of Ottawa","funders":"","keywords":"Depressive symptoms; Schizophrenia (object-oriented programming); Medicine; Clinical psychology; MEDLINE; Psychiatry; Psychology; Cognition; Biology","score_opus":0.01899108159750408,"score_gpt":0.26794330647610054,"score_spread":0.24895222487859647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225014396","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011384434,0.0074755712,0.012170772,0.041673955,0.67740715,0.006217213,0.0013119391,0.002545223,0.23981377],"genre_scores_gemma":[0.13312094,0.0035608248,0.050614636,0.15784684,0.070109144,0.007834495,0.01808218,0.0043793395,0.5544516],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954751,0.00031629673,0.00081190746,0.0014077039,0.001309831,0.0006791462],"domain_scores_gemma":[0.9983346,0.00044982228,0.0004003358,0.0005129359,0.00008222949,0.00022008539],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022550301,0.00068206294,0.0004847904,0.0007622866,0.0009606762,0.00019757327,0.0009529552,0.0005330811,0.0011823204],"category_scores_gemma":[0.00014112044,0.0007646042,0.0003659585,0.0010959195,0.00015897289,0.0003329208,0.00014917829,0.0014490286,0.00018257565],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021671102,0.000100901154,0.0017499207,0.00043564537,0.00014186358,0.000016682305,0.0010197745,0.0011205274,0.00038501178,0.0031429927,0.9885324,0.0031375526],"study_design_scores_gemma":[0.0016635951,0.00013992292,0.015677832,0.0017870326,0.000100730416,0.0001107171,0.00053220947,0.0016726754,0.0005450112,0.0044998177,0.9711195,0.0021509237],"about_ca_topic_score_codex":0.000015054028,"about_ca_topic_score_gemma":0.00013091812,"teacher_disagreement_score":0.60729796,"about_ca_system_score_codex":0.00019103674,"about_ca_system_score_gemma":0.0020707338,"threshold_uncertainty_score":0.9997307},"labels":[],"label_agreement":null},{"id":"W4225375584","doi":"10.1101/2022.04.24.22273790","title":"Specificity of cortical area and thickness as biomarkers for comorbid internalizing and externalizing mental disorders in pre-adolescence","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Higher Education Discipline Innovation Project; National Natural Science Foundation of China","keywords":"Comorbidity; Panic disorder; Psychology; Agoraphobia; Anxiety; Clinical psychology; Anxiety disorder; Specific phobia; Major depressive disorder; Generalized anxiety disorder; Separation anxiety disorder; Conduct disorder; Psychiatry; Mood disorders; Mood","score_opus":0.037156127609964215,"score_gpt":0.3030137242947902,"score_spread":0.26585759668482595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225375584","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99563295,0.0005672027,0.0013507623,0.00036728094,0.00053892966,0.0009676339,0.00008781727,0.000039633578,0.00044781866],"genre_scores_gemma":[0.9982877,0.0010328757,0.0003091204,0.0001646759,0.000019338475,0.00009133275,0.0000069567573,0.0000350609,0.000052988267],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99765193,0.00026870467,0.00048930274,0.0008802398,0.0003688595,0.00034098653],"domain_scores_gemma":[0.9988007,0.0005032337,0.00025849498,0.00031265782,0.000015172005,0.000109738394],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050018745,0.0003017156,0.0004278903,0.00022390552,0.00013773235,0.00008102743,0.00049360225,0.00012410565,0.00009568504],"category_scores_gemma":[0.0006141932,0.0003078465,0.00010797042,0.00016799613,0.00054962223,0.00009447881,0.0011738413,0.0005998073,5.5470764e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011934183,0.0004818651,0.6392839,0.0013488141,0.00004450543,0.00003599115,0.0057893964,0.00007021455,0.34103698,0.0020822387,0.000066314984,0.008566376],"study_design_scores_gemma":[0.003927019,0.0004507224,0.86887395,0.001852483,0.000057272136,0.000089303125,0.003172807,0.013156071,0.08935323,0.0154897785,0.0021712035,0.0014061775],"about_ca_topic_score_codex":0.00029989568,"about_ca_topic_score_gemma":0.000200479,"teacher_disagreement_score":0.25168374,"about_ca_system_score_codex":0.00006014748,"about_ca_system_score_gemma":0.000053134136,"threshold_uncertainty_score":0.99993736},"labels":[],"label_agreement":null},{"id":"W4226075339","doi":"10.1038/s41380-022-01552-4","title":"The tryptophan catabolite or kynurenine pathway in schizophrenia: meta-analysis reveals dissociations between central, serum, and plasma compartments","year":2022,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":84,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Kynurenine; Kynurenine pathway; Kynurenic acid; Quinolinic acid; Xanthurenic acid; Tryptophan; Internal medicine; Schizophrenia (object-oriented programming); Endocrinology; Chemistry; Medicine; Biochemistry; Psychiatry; Amino acid","score_opus":0.09588818499143253,"score_gpt":0.3397412911211349,"score_spread":0.24385310612970235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226075339","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018258295,0.9928293,0.000027334765,0.0007088483,0.00051467214,0.0014985888,0.0022502851,0.000080762664,0.0002643685],"genre_scores_gemma":[0.004960993,0.9922027,0.0002784124,0.0004501585,0.00011876502,0.0006588048,0.0004621884,0.0001226081,0.0007453963],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9940177,0.0018356454,0.0012366249,0.0012673237,0.0007765153,0.0008661837],"domain_scores_gemma":[0.99701273,0.0008506043,0.00078311417,0.0010856636,0.000016031752,0.0002518345],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004637632,0.0007818937,0.0030595732,0.00053818687,0.0007545459,0.0002748278,0.0011212062,0.00022098774,0.00036061794],"category_scores_gemma":[0.0003096273,0.0005093932,0.0022207028,0.0033619758,0.00017412596,0.00010696536,0.00034575135,0.0009432957,0.000022810353],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036339194,0.0027405976,0.0022434378,0.009589102,0.20007193,0.00066481123,0.0009722024,0.00018365757,0.00007992653,0.03588295,0.007827671,0.7393803],"study_design_scores_gemma":[0.0009867805,0.00007148534,0.0007600263,0.00011502315,0.052849837,0.000017299844,0.000060310747,0.00001180034,0.000024326242,0.0009672065,0.94326407,0.00087181764],"about_ca_topic_score_codex":0.000022461134,"about_ca_topic_score_gemma":0.00034068167,"teacher_disagreement_score":0.9354364,"about_ca_system_score_codex":0.00011768453,"about_ca_system_score_gemma":0.000401269,"threshold_uncertainty_score":0.9997358},"labels":[],"label_agreement":null},{"id":"W4226094208","doi":"10.1038/s41380-021-01407-4","title":"Inflammation and nitro-oxidative stress in current suicidal attempts and current suicidal ideation: a systematic review and meta-analysis","year":2022,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":105,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Chulalongkorn University","keywords":"Meta-analysis; Suicidal ideation; Oxidative stress; Immune system; Internal medicine; Medicine; Confidence interval; Inflammation; Web of science; Oncology; Poison control; Immunology; Injury prevention","score_opus":0.07101488276035507,"score_gpt":0.3540780055899416,"score_spread":0.28306312282958657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226094208","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002612669,0.99538124,0.00013669401,0.00031633422,0.00018303958,0.0034189287,0.00022458432,0.000036534806,0.000041374955],"genre_scores_gemma":[0.00042108155,0.99798197,0.00005335461,0.00021098564,0.000025203135,0.0010889132,0.00014965617,0.000048027636,0.000020792648],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9946321,0.0019361911,0.001316973,0.0011673437,0.0006013548,0.00034604213],"domain_scores_gemma":[0.99795675,0.0003042595,0.00093384855,0.00062156265,0.000031062686,0.0001525247],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006328965,0.000698197,0.0040129195,0.00068748416,0.00016855614,0.00016858918,0.00034535053,0.000106054664,0.00014348011],"category_scores_gemma":[0.00037356935,0.0005561583,0.00088235637,0.0014635971,0.00012523054,0.00017179041,0.0002877595,0.00066280446,0.0000071627237],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004606958,0.00016030691,0.000055951954,0.9764117,0.006400369,0.00002041765,0.00011530911,0.000005025343,0.0000053663703,0.0014375648,0.00005308423,0.015330294],"study_design_scores_gemma":[0.0012209312,0.00021296872,0.00007692702,0.046196196,0.91263443,0.00020129509,0.000200104,0.00012463545,0.00004068893,0.0012514128,0.034929838,0.0029105828],"about_ca_topic_score_codex":0.000019468614,"about_ca_topic_score_gemma":0.0000955013,"teacher_disagreement_score":0.9302155,"about_ca_system_score_codex":0.000065201675,"about_ca_system_score_gemma":0.00014639205,"threshold_uncertainty_score":0.999689},"labels":[],"label_agreement":null},{"id":"W4226141352","doi":"10.1002/trc2.12283","title":"Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia Translational Research & Clinical Interventions","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Queen's University; University Health Network; Dalhousie University","funders":"","keywords":"Innate immune system; Microglia; Neuroscience; Biology; Immunology; Immunity; Inflammation; Cell biology; Immune system","score_opus":0.22585252020179292,"score_gpt":0.4530763106408799,"score_spread":0.22722379043908697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226141352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9128317,0.07717571,0.0008425132,0.0034304624,0.0005608298,0.0018442617,0.0019568242,0.00020006699,0.0011576323],"genre_scores_gemma":[0.9974176,0.00047927303,0.0002906531,0.00031340658,0.000046964375,0.00042973994,0.00083303073,0.00006964429,0.00011966297],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.98914665,0.005081884,0.0018855972,0.0010115202,0.0020267135,0.00084761943],"domain_scores_gemma":[0.99597037,0.0018913794,0.00035008093,0.0009334732,0.00033195896,0.00052275305],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0035748507,0.00033636615,0.000518971,0.0004984319,0.0015789187,0.00012439821,0.0016029482,0.00011056204,0.009440919],"category_scores_gemma":[0.0010497475,0.00035592276,0.0011204614,0.0015207003,0.0011804763,0.0006630634,0.0005207203,0.001392494,0.00009727836],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0071946667,0.081481576,0.02872936,0.00021216909,0.025976315,0.00018959468,0.0035014942,0.0036867743,0.32212228,0.19216497,0.008270477,0.32647032],"study_design_scores_gemma":[0.021701884,0.00919185,0.44795108,0.00032252033,0.010280403,0.00004688182,0.0027575623,0.028916866,0.10177426,0.2224014,0.15104455,0.0036107611],"about_ca_topic_score_codex":0.00068818615,"about_ca_topic_score_gemma":0.00008873305,"teacher_disagreement_score":0.4192217,"about_ca_system_score_codex":0.000014948432,"about_ca_system_score_gemma":0.00041983812,"threshold_uncertainty_score":0.99988925},"labels":[],"label_agreement":null},{"id":"W4226256211","doi":"10.1016/b978-0-323-90905-1.00001-8","title":"Novel therapeutic approaches targeting oxidative stress in mood disorders","year":2022,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Oxidative stress; Monoaminergic; Reactive oxygen species; Mood disorders; Neuroscience; Major depressive disorder; Mood; Reactive nitrogen species; Medicine; Pharmacology; Biology; Cell biology; Internal medicine; Psychiatry; Serotonin; Receptor","score_opus":0.045816756131460336,"score_gpt":0.24572875557651874,"score_spread":0.1999119994450584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226256211","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004612764,0.00064499985,0.000017726052,0.00019034477,0.00031128593,0.0010201817,0.00016274859,0.000119942655,0.9970715],"genre_scores_gemma":[0.16907929,0.00024097635,0.0001343329,0.00068017276,0.000120280325,0.00022855852,0.000053442975,0.00022294637,0.82924],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972803,0.00011275819,0.0005130128,0.00094858825,0.0005879944,0.0005573443],"domain_scores_gemma":[0.99874496,0.00031389465,0.00032828987,0.00050342025,0.000012751823,0.00009665696],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022556633,0.0006077158,0.00054603216,0.0004259864,0.0002492292,0.00007226639,0.0007795748,0.00023906479,0.0007853674],"category_scores_gemma":[0.00008224834,0.0006014378,0.00026462282,0.00008446692,0.00033145642,0.00010842847,0.00037295086,0.0011382606,0.000052326297],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051338313,0.000151304,0.000028615264,0.000118649725,0.00004371206,0.00001050006,0.0027144246,0.000070995324,0.0075987116,0.07120697,0.000015801837,0.91798896],"study_design_scores_gemma":[0.0016767884,0.00018862581,0.0000767461,0.00023171914,0.000047671492,0.000010191555,0.0009541275,0.00015382888,0.0065944125,0.032661956,0.9557519,0.0016520163],"about_ca_topic_score_codex":0.0000026151024,"about_ca_topic_score_gemma":0.00015540575,"teacher_disagreement_score":0.9557361,"about_ca_system_score_codex":0.00013398303,"about_ca_system_score_gemma":0.00011902438,"threshold_uncertainty_score":0.9996437},"labels":[],"label_agreement":null},{"id":"W4230940332","doi":"10.3410/f.717957914.793465232","title":"Faculty Opinions recommendation of Astrocyte senescence as a component of Alzheimer's disease.","year":2012,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Astrocyte; Component (thermodynamics); Disease; Senescence; Alzheimer's disease; Neuroscience; Gerontology; Medicine; Psychology; Internal medicine; Physics; Central nervous system","score_opus":0.05075890210842265,"score_gpt":0.35537524548716426,"score_spread":0.3046163433787416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4230940332","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000026373589,0.0018598879,0.000029807818,0.089514874,0.00089546293,0.0014077848,0.90620065,0.00003698986,0.000051898787],"genre_scores_gemma":[0.00022134278,0.0005038685,0.00025116926,0.004376643,0.00018463781,0.00015243825,0.9940854,0.000028273269,0.0001962836],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9943972,0.0007966218,0.0017008309,0.00075596635,0.0018935484,0.0004558134],"domain_scores_gemma":[0.9931439,0.0002572915,0.0021972675,0.0016084745,0.0022848682,0.00050821184],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000906978,0.0005603836,0.0009931279,0.00036509396,0.00020821807,0.00007422111,0.0019814223,0.0004286858,0.00073756214],"category_scores_gemma":[0.008474533,0.00037724723,0.0007589372,0.0019689412,0.00073478033,0.00040421129,0.0006509918,0.0008173927,0.00010290194],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033347766,0.00075493153,0.0000063586967,0.0043255766,0.00006636893,2.687717e-7,0.00006741949,1.4588836e-7,0.00007835096,0.0005071981,0.9923919,0.001768152],"study_design_scores_gemma":[0.0005819156,0.000095780066,0.0023553811,0.0076349783,0.00020033724,0.00002032711,0.000018734218,0.000006876696,0.0008498069,0.000029831855,0.9878771,0.00032896674],"about_ca_topic_score_codex":0.00004138448,"about_ca_topic_score_gemma":0.0000014782097,"teacher_disagreement_score":0.08788469,"about_ca_system_score_codex":0.000060668193,"about_ca_system_score_gemma":0.00055743346,"threshold_uncertainty_score":0.9998775},"labels":[],"label_agreement":null},{"id":"W4231812510","doi":"10.1176/appi.psy.51.6.466","title":"Dose-Dependent Development of Depressive Symptoms During Adjuvant Interferon-  Treatment of Patients With Malignant Melanoma","year":2010,"lang":"en","type":"article","venue":"Psychosomatics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Melanoma; Medicine; Adjuvant; Oncology; Internal medicine; Interferon alfa; Depressive symptoms; Interferon; Alpha interferon; Immunology; Psychiatry; Cancer research; Anxiety","score_opus":0.012531657305337132,"score_gpt":0.2407011458768422,"score_spread":0.22816948857150504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4231812510","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984331,0.00002203683,0.00018064288,0.000014049583,0.0002855406,0.00046736954,0.000030130297,0.00003653987,0.0005305781],"genre_scores_gemma":[0.9977854,0.000011330949,0.0020325852,0.000014685776,0.000013820314,0.0000401951,0.000004454309,0.000028350216,0.00006920709],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852794,0.000031880514,0.00048131554,0.00031219126,0.00039093778,0.00025572735],"domain_scores_gemma":[0.99901634,0.000077468474,0.00034634725,0.00041222599,0.000057099536,0.000090505826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000028425622,0.0002179625,0.00030006786,0.000109545166,0.00007304548,0.000014782667,0.00027072648,0.00006266089,0.000076526354],"category_scores_gemma":[0.00003411841,0.00015124895,0.000055833436,0.00013421776,0.000121136145,0.000080664446,0.000046101144,0.000072167204,0.00001538781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064081314,0.004321007,0.23260814,0.00030753593,0.00013625085,0.000014007163,0.0112064425,0.000025416104,0.7182054,0.00032790442,0.000010664499,0.03219642],"study_design_scores_gemma":[0.002759227,0.0004534255,0.27651116,0.0000949827,0.000014285356,0.0000032170046,0.00009291004,0.000037039536,0.71974546,0.00006047488,0.00006115405,0.0001666517],"about_ca_topic_score_codex":0.0000045194233,"about_ca_topic_score_gemma":0.000040702726,"teacher_disagreement_score":0.04390301,"about_ca_system_score_codex":0.00003416331,"about_ca_system_score_gemma":0.000050916853,"threshold_uncertainty_score":0.61677533},"labels":[],"label_agreement":null},{"id":"W4231913675","doi":"10.1093/schbul/sbx022.001","title":"M2. Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis","year":2017,"lang":"en","type":"review","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Kynurenic acid; Kynurenine; Schizophrenia (object-oriented programming); Meta-analysis; Subgroup analysis; Medicine; Psychosis; PsycINFO; Strictly standardized mean difference; Internal medicine; Neuroscience; Psychology; MEDLINE; Psychiatry; Glutamate receptor; Tryptophan; Chemistry; Receptor","score_opus":0.11745423773312547,"score_gpt":0.3485565901818372,"score_spread":0.23110235244871175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4231913675","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000011762315,0.9924943,0.000007057292,0.0011585116,0.000116118645,0.0049388446,0.00030903475,0.00016561331,0.00080937194],"genre_scores_gemma":[0.00007263436,0.99328953,0.00033395836,0.0011158083,0.00005946212,0.0020338853,0.000051355444,0.0001555174,0.002887839],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9906329,0.0025258306,0.0026219287,0.0023973223,0.00085756934,0.00096445647],"domain_scores_gemma":[0.99303466,0.00091519766,0.0023293623,0.0032918754,0.00006409151,0.00036484172],"candidate_categories":["metaepi_narrow","metaepi_broad","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.0016741693,0.0016489709,0.01721111,0.0013883105,0.00041865328,0.00054383354,0.0025586635,0.00064489123,0.0021913177],"category_scores_gemma":[0.00421509,0.0011503638,0.0055777966,0.0018711567,0.0004292246,0.00015259851,0.00066125416,0.0015307078,0.0019290324],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003988265,0.0001278499,6.1137214e-8,0.9609156,0.026337994,0.00018807422,0.000024464907,2.9409173e-7,0.0000016815624,0.00088513416,0.00190603,0.009572912],"study_design_scores_gemma":[0.00069061824,0.00004070566,7.01569e-7,0.044745825,0.6596398,0.00016344036,0.000004221369,0.0000013947142,0.0000052868977,0.00015653824,0.29326728,0.001284203],"about_ca_topic_score_codex":0.00003402689,"about_ca_topic_score_gemma":0.000119050834,"teacher_disagreement_score":0.9161698,"about_ca_system_score_codex":0.00010193679,"about_ca_system_score_gemma":0.00029887244,"threshold_uncertainty_score":0.99962574},"labels":[],"label_agreement":null},{"id":"W4233081156","doi":"10.1038/s41386-021-00992-w","title":"Correction to: Elevated fatty acid amide hydrolase in the prefrontal cortex of borderline personality disorder: a [11C] CURB positron emission tomography study","year":2021,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Waypoint Centre for Mental Health Care; Centre for Addiction and Mental Health","funders":"","keywords":"Positron emission tomography; Prefrontal cortex; Fatty acid amide hydrolase; Psychology; Borderline personality disorder; Neuroscience; Clinical psychology; Internal medicine; Medicine; Cognition","score_opus":0.014894477827564848,"score_gpt":0.3028504459841029,"score_spread":0.287955968156538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233081156","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99459976,0.00014090692,0.000064881526,0.0010840335,0.0019364586,0.001135735,0.000037556438,0.00008803172,0.00091265095],"genre_scores_gemma":[0.9951518,0.00007339892,0.00002198234,0.0043782755,0.00006445567,0.00010722292,0.000017465181,0.00003203276,0.00015336554],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9959034,0.001730099,0.0005349504,0.000908979,0.0004472243,0.00047538566],"domain_scores_gemma":[0.9987107,0.00045618156,0.00018253991,0.00042987795,0.00008460143,0.00013613614],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002959977,0.00029855917,0.00036072676,0.00023159572,0.00018857344,0.000035584435,0.00052322244,0.00008620818,0.00024923947],"category_scores_gemma":[0.00045303872,0.00024944652,0.00014663704,0.0017588967,0.0001492071,0.00013146685,0.0001267847,0.00066379237,0.000025221818],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011856523,0.003707278,0.023737209,0.000017496592,0.0000141256205,0.00020333074,0.0014462958,0.000067500085,0.965189,0.000007712271,0.0021518671,0.0022725582],"study_design_scores_gemma":[0.005423243,0.0017342658,0.7447277,0.000019463068,0.00004935438,0.000106347965,0.0012334969,0.001405981,0.24210769,0.000042177868,0.0028305564,0.00031975194],"about_ca_topic_score_codex":0.00013279714,"about_ca_topic_score_gemma":0.00038819594,"teacher_disagreement_score":0.7230813,"about_ca_system_score_codex":0.000034871853,"about_ca_system_score_gemma":0.0000847755,"threshold_uncertainty_score":0.99999577},"labels":[],"label_agreement":null},{"id":"W4234219213","doi":"10.1016/b978-0-12-811351-6.00013-9","title":"Schizophrenia","year":2018,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Royal Ottawa Mental Health Centre","funders":"","keywords":"Schizophrenia (object-oriented programming); Immune system; Disease; Immunology; Cytokine; Psychology; Neuroscience; Psychiatry; Medicine; Internal medicine","score_opus":0.024865612437683687,"score_gpt":0.246848935244107,"score_spread":0.22198332280642333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4234219213","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00030442097,0.00023673414,0.0000014216758,0.00006399648,0.0007267356,0.00038344524,0.000042494485,0.00022967465,0.99801105],"genre_scores_gemma":[0.0015520982,0.00006353057,0.00013299193,0.0020550461,0.0007034979,0.000015578478,0.0000046593573,0.00012861622,0.995344],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99807405,0.000030218824,0.0003248673,0.0007796832,0.0004170173,0.000374131],"domain_scores_gemma":[0.99879104,0.00009901922,0.00019428653,0.0007214563,0.00003779239,0.00015642233],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00008727589,0.0004549792,0.00038648458,0.00016949193,0.00017231294,0.00008360238,0.0005965794,0.0003409875,0.003925511],"category_scores_gemma":[0.00009093305,0.00041795935,0.00026006854,0.000016175874,0.00052223523,0.000045798977,0.00019895489,0.0004594192,0.007537088],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003723368,0.0000065025856,1.1911468e-7,0.000029815756,0.0000110218,0.000045016634,0.000112159214,2.0801744e-8,0.0026893558,0.02497487,0.0026485645,0.96944535],"study_design_scores_gemma":[0.00034718614,0.00006638437,0.0000020724337,0.00013909451,0.000016128997,0.000023548339,0.000002196678,0.0000016251588,0.0072575063,0.0644919,0.9272026,0.00044979397],"about_ca_topic_score_codex":7.490304e-8,"about_ca_topic_score_gemma":0.000007836641,"teacher_disagreement_score":0.9689955,"about_ca_system_score_codex":0.000039668234,"about_ca_system_score_gemma":0.000114549686,"threshold_uncertainty_score":0.9998272},"labels":[],"label_agreement":null},{"id":"W4235712742","doi":"10.22215/etd/2020-14356","title":"A Personalized Approach to Understanding Depression: Examining the Biological and Psychosocial Basis of Symptom Clusters","year":2020,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"World Health Organization","keywords":"Psychosocial; Depression (economics); Anxiety; Clinical psychology; Psychology; Depressive symptoms; Psychiatry; Medicine","score_opus":0.12893418567799247,"score_gpt":0.30929944350044275,"score_spread":0.18036525782245028,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4235712742","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.71157527,0.00034263008,0.0077099237,0.0015249257,0.0005795498,0.0014685945,0.00003060154,0.0001405802,0.2766279],"genre_scores_gemma":[0.99702674,0.00010363996,0.00061734475,0.001210688,0.00005960772,0.000039637245,0.000027611784,0.000023040568,0.000891692],"study_design_codex":"bench_or_experimental","study_design_gemma":"qualitative","domain_scores_codex":[0.9983788,0.00026359342,0.00023994375,0.00060445693,0.00029989614,0.00021328102],"domain_scores_gemma":[0.99896586,0.00063893606,0.00014275486,0.00013871062,0.000010896525,0.00010286952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016234015,0.00022742675,0.0003126158,0.00008404044,0.00022472464,0.00006776278,0.00032175187,0.00024861615,0.000118948774],"category_scores_gemma":[0.0005144453,0.00014167333,0.00009338398,0.0003933107,0.00014903712,0.00004549794,0.000060095255,0.0002773106,0.0000050966496],"study_design_candidate":"qualitative","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0065098973,0.00087005727,0.003476418,0.0014209377,0.00032906648,0.000025038566,0.21787843,0.000039725066,0.5309693,0.18700756,0.016677706,0.034795847],"study_design_scores_gemma":[0.009993971,0.0015132955,0.028761294,0.0012026306,0.0003031859,0.000058952082,0.7950361,0.0036376773,0.13478501,0.013365731,0.007467359,0.0038748197],"about_ca_topic_score_codex":0.0000052558808,"about_ca_topic_score_gemma":0.0000072105518,"teacher_disagreement_score":0.5771577,"about_ca_system_score_codex":0.000035963876,"about_ca_system_score_gemma":0.000044369626,"threshold_uncertainty_score":0.5777271},"labels":[],"label_agreement":null},{"id":"W4238225184","doi":"10.21203/rs.3.rs-152636/v1","title":"Plasma concentrations of Granulocyte Colony-Stimulating Factor (G-CSF) in Patients with Substance Use Disorders and Comorbid Major Depressive Disorders","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Major depressive disorder; Addiction; Internal medicine; Abstinence; Medicine; Alcohol use disorder; Comorbidity; Psychiatry; Substance abuse; Alcohol; Psychology; Amygdala","score_opus":0.0487900930665127,"score_gpt":0.3257687878785515,"score_spread":0.2769786948120388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238225184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99595785,0.00023689946,0.00013144157,0.00019622756,0.00010845449,0.002493942,0.0006058492,0.000049460745,0.0002198903],"genre_scores_gemma":[0.9985783,0.00069821265,0.00021102448,0.000029588982,0.000012430742,0.00019483845,0.0001534036,0.00006318169,0.000058997623],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99519,0.0008699428,0.0005122758,0.0011991665,0.0013837571,0.0008448155],"domain_scores_gemma":[0.9964909,0.0020015265,0.0002614898,0.000683163,0.00034837736,0.00021455593],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020896239,0.0004026074,0.0005606007,0.0004046001,0.00033773662,0.00032349525,0.0005119086,0.00027458277,0.00007779409],"category_scores_gemma":[0.001973401,0.00037735654,0.000105121624,0.0009153608,0.000980153,0.00045417782,0.0005414586,0.0013766837,0.0000026538737],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048700997,0.0005976935,0.9894621,0.0006258887,0.000027169974,0.00002102102,0.0024790915,0.0029227359,0.0014651634,0.00022484668,0.00003302501,0.0016542529],"study_design_scores_gemma":[0.0045974245,0.00034163162,0.98418915,0.0010584078,0.000010038504,6.024006e-7,0.0008372508,0.0031910604,0.0048633874,0.00033945634,0.00006969483,0.0005018672],"about_ca_topic_score_codex":0.0010332623,"about_ca_topic_score_gemma":0.0142959645,"teacher_disagreement_score":0.013262702,"about_ca_system_score_codex":0.00015065208,"about_ca_system_score_gemma":0.00035046402,"threshold_uncertainty_score":0.99986786},"labels":[],"label_agreement":null},{"id":"W4239905910","doi":"10.21203/rs.3.rs-23307/v1","title":"Higher inflammation and cerebral white matter injury associated cognitive deficit in asthmatic patients with depression","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Depression (economics); Medicine; Cognition; Inflammation; White matter; Psychology; Clinical psychology; Internal medicine; Psychiatry; Magnetic resonance imaging; Economics","score_opus":0.03736185636001447,"score_gpt":0.3243108903499364,"score_spread":0.2869490339899219,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239905910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950822,0.00003103757,0.000019392202,0.0008685132,0.00006243706,0.001566693,0.00019543398,0.000065031876,0.002109273],"genre_scores_gemma":[0.99918735,0.000013674894,0.000022812183,0.00015797408,0.000036389058,0.00018632547,0.00018070941,0.000050839175,0.0001639518],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99613416,0.0010116313,0.0003076771,0.0008440096,0.0011659355,0.00053660077],"domain_scores_gemma":[0.9988086,0.00041172124,0.00015951274,0.00024243307,0.00022130192,0.0001563934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032218572,0.0002693208,0.00031206445,0.00042175798,0.00015500159,0.00025769643,0.00027002353,0.00028251766,0.0002574499],"category_scores_gemma":[0.0010418477,0.0002242738,0.000044445536,0.00061730226,0.00016661648,0.00022535141,0.00089960493,0.0014290102,0.00016649581],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045678247,0.00019274323,0.9943898,0.0006723248,0.000012086912,0.00002368625,0.0012239378,0.000024116114,0.000561814,0.000041045707,0.00050012564,0.0019015506],"study_design_scores_gemma":[0.0014655644,0.0001933822,0.99279743,0.0016999806,0.000005033785,2.843388e-7,0.0002298914,0.000331994,0.0016325711,0.0013524849,0.000019649753,0.00027174587],"about_ca_topic_score_codex":0.000055220346,"about_ca_topic_score_gemma":0.000100893165,"teacher_disagreement_score":0.004105136,"about_ca_system_score_codex":0.00014316199,"about_ca_system_score_gemma":0.000119002,"threshold_uncertainty_score":0.914562},"labels":[],"label_agreement":null},{"id":"W4239946193","doi":"10.1002/(sici)1099-1077(200004)15:3<199::aid-hup163>3.3.co;2-k","title":"The interaction between cytokines and neurotransmitters in depression and stress: possible mechanism of antidepressant treatments","year":2000,"lang":"en","type":"article","venue":"Human Psychopharmacology Clinical and Experimental","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Nucleus accumbens; Antidepressant; Psychology; Depression (economics); Psychiatry; Neuroscience; Dopamine; Anxiety","score_opus":0.0501237004069989,"score_gpt":0.399544832697158,"score_spread":0.34942113229015914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239946193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99836296,0.0005406206,0.0000011422223,0.00014620538,0.00017305436,0.0002636632,0.000014062738,0.000017548326,0.00048075453],"genre_scores_gemma":[0.9977266,0.0016846801,0.000012191041,0.0004146959,0.00005031874,0.000025010695,0.0000018362989,0.000010055812,0.00007460456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987068,0.00023108034,0.00038544709,0.0004161915,0.000083412,0.00017706888],"domain_scores_gemma":[0.9993801,0.00036023054,0.00007521709,0.00009198547,0.000003852354,0.00008862747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010890548,0.0001393373,0.00021181234,0.00004783125,0.00021836405,0.000029689843,0.0001032379,0.00007711672,0.000112319365],"category_scores_gemma":[0.000010340643,0.00009814751,0.000039673025,0.000056363777,0.00055490766,0.00012919563,0.000046953264,0.00017786688,0.000002045233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022208064,0.00087694207,0.24161384,0.000021542744,0.000042421518,0.000032035685,0.00096735184,0.0000024935707,0.6976944,0.00024440934,0.00016458836,0.05611915],"study_design_scores_gemma":[0.016277075,0.0010479967,0.40063843,0.00007273183,0.00003920018,0.00003052906,0.00061341864,0.0002880791,0.5785677,0.0016401629,0.0005090677,0.00027563304],"about_ca_topic_score_codex":0.00002696997,"about_ca_topic_score_gemma":0.0000063374328,"teacher_disagreement_score":0.15902461,"about_ca_system_score_codex":0.0000041065664,"about_ca_system_score_gemma":0.0000039340857,"threshold_uncertainty_score":0.40023392},"labels":[],"label_agreement":null},{"id":"W4240496532","doi":"10.3410/f.13440959.14815058","title":"Faculty Opinions recommendation of Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging.","year":2012,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Epigenetics; Synaptic plasticity; Neuroscience; Neuroplasticity; Plasticity; Psychology; Biology; Genetics; Materials science; Gene; Composite material","score_opus":0.04595550210633353,"score_gpt":0.34907399185962906,"score_spread":0.30311848975329553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240496532","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00002383042,0.0010636133,0.00011339358,0.037316773,0.0006268796,0.0012347719,0.95956516,0.000021187101,0.000034418073],"genre_scores_gemma":[0.0011936831,0.0005799771,0.00032424607,0.0018990805,0.000119568314,0.00014904229,0.9955533,0.000022006485,0.0001590744],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948187,0.00075548637,0.00190983,0.0006754138,0.0013922025,0.00044839655],"domain_scores_gemma":[0.99513555,0.00050306146,0.0017219583,0.0009279068,0.001496232,0.00021527862],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010696468,0.00046424227,0.0009569264,0.0005048301,0.00013550426,0.00005770105,0.0015585589,0.0004605241,0.00062760606],"category_scores_gemma":[0.012449229,0.0003218044,0.00042265438,0.0021868867,0.000498415,0.000269761,0.00046375865,0.0008406691,0.000034999073],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015994443,0.00068808865,0.000006571331,0.007384788,0.000042485437,1.6001336e-7,0.00020498791,7.042169e-7,0.00044805885,0.00017499732,0.9896078,0.0014253415],"study_design_scores_gemma":[0.0005624415,0.0001274446,0.0007269109,0.011344567,0.00007476913,0.000007725242,0.000036383022,0.000016158136,0.004822386,0.000034305835,0.98195946,0.00028745222],"about_ca_topic_score_codex":0.000055943583,"about_ca_topic_score_gemma":0.000009512783,"teacher_disagreement_score":0.03598819,"about_ca_system_score_codex":0.000105315165,"about_ca_system_score_gemma":0.00034215132,"threshold_uncertainty_score":0.9999234},"labels":[],"label_agreement":null},{"id":"W4240520511","doi":"10.21203/rs.3.rs-60074/v2","title":"Differential Effects of Chronic Immunosuppression on Behavioral, Epigenetic and Alzheimer’s Disease-Associated Markers in 3xtg-AD Mice&amp;nbsp;","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McMaster University","funders":"Canadian Institutes of Health Research; Consortium canadien en neurodégénérescence associée au vieillissement","keywords":"Immunosuppression; Epigenetics; Disease; Alzheimer's disease; Medicine; Neuroscience; Differential (mechanical device); Immunology; Psychology; Biology; Internal medicine; Genetics; Physics; Gene","score_opus":0.08926353322244047,"score_gpt":0.38681655222614236,"score_spread":0.2975530190037019,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240520511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99193263,0.004388185,0.000009611275,0.0005004226,0.00036779078,0.002380269,0.00025300178,0.000076692384,0.00009140019],"genre_scores_gemma":[0.99600977,0.0033143118,0.000009041483,0.000029313114,0.000049093742,0.00027760796,0.00014209563,0.00007929698,0.000089448644],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9939696,0.0018930816,0.00047013204,0.0013123305,0.0014642479,0.00089057913],"domain_scores_gemma":[0.9972929,0.0012562636,0.00019773784,0.00075930683,0.0000922318,0.0004016118],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025364466,0.0004434929,0.0006004373,0.0005815608,0.0002007084,0.00014823671,0.0008398532,0.00039103618,0.0001979733],"category_scores_gemma":[0.0016847788,0.0004213456,0.0002281962,0.00059976184,0.00053349335,0.0000709936,0.0016837874,0.0018938673,0.000044803677],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002486481,0.004870969,0.004105114,0.0053517446,0.00009973717,0.0004090297,0.0013761799,0.00021460271,0.95249045,0.000074993375,0.00243105,0.026089638],"study_design_scores_gemma":[0.006476033,0.0033818025,0.646963,0.010886258,0.00016389624,0.0000017040775,0.00019674395,0.0032413676,0.32388446,0.0028175788,0.0005588733,0.0014282742],"about_ca_topic_score_codex":0.00022225206,"about_ca_topic_score_gemma":0.00013767698,"teacher_disagreement_score":0.6428579,"about_ca_system_score_codex":0.00027489642,"about_ca_system_score_gemma":0.00046222468,"threshold_uncertainty_score":0.9998238},"labels":[],"label_agreement":null},{"id":"W4243150068","doi":"10.22215/etd/2015-11044","title":"Exploring the Neuroplastic and Antidepressant-Like Effects of Erythropoietin","year":2015,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Erythropoietin; Neuroplasticity; Antidepressant; Behavioural despair test; Doublecortin; Animal models of depression; Neurogenesis; Neuroscience; Psychology; Medicine; Depression (economics); Animal studies; Cognition; Pharmacology; Internal medicine; Central nervous system; Hippocampus","score_opus":0.050220036855601294,"score_gpt":0.27159899470944776,"score_spread":0.22137895785384648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243150068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887897,0.0003002703,0.000009664635,0.000040419105,0.0018419328,0.00032493807,0.0000033436022,0.00006363405,0.008626108],"genre_scores_gemma":[0.9959977,0.000732128,0.000014064237,0.00013857293,0.0000431954,0.00003571816,0.000007618236,0.000037344835,0.002993652],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878,0.00012382762,0.00019407866,0.00037471968,0.00033263242,0.00019471104],"domain_scores_gemma":[0.99864614,0.0008647944,0.00013012075,0.00026106747,0.000036796857,0.00006107517],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000717694,0.00020764739,0.00023124261,0.00008909961,0.000094022376,0.000044425928,0.00024814458,0.000057324894,0.000019746047],"category_scores_gemma":[0.0010519997,0.00013529493,0.00005503292,0.00019376176,0.00012598513,0.0001353311,0.00005008465,0.00021814367,0.000020784428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005132066,0.0003062676,0.0002936886,0.0034999498,0.00004186363,0.00013217806,0.006984181,0.00003687062,0.915163,0.00420195,0.012949001,0.055877853],"study_design_scores_gemma":[0.0012152736,0.0003731397,0.04222144,0.00043414225,0.00007723013,0.000022900445,0.002364748,0.00014849848,0.9475629,0.001120959,0.0038731627,0.000585629],"about_ca_topic_score_codex":0.00003285312,"about_ca_topic_score_gemma":0.000042836262,"teacher_disagreement_score":0.055292223,"about_ca_system_score_codex":0.0000048812794,"about_ca_system_score_gemma":0.00004232392,"threshold_uncertainty_score":0.55171674},"labels":[],"label_agreement":null},{"id":"W4244822879","doi":"10.20944/preprints201810.0083.v1","title":"In Schizophrenia, Low Natural IgM Antibody Titers to Oxidative Specific Epitopes and Higher IgM Responses to Nitrated and Nitrosylated Proteins Strongly Predict Negative Symptoms, Neurocognitive Impairments and the Deficit Syndrome","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University; Asahi Glass Foundation","keywords":"Schizophrenia (object-oriented programming); Antibody; Immunology; Autoantibody; Internal medicine; Chemistry; Psychology; Medicine; Psychiatry","score_opus":0.03824197531365304,"score_gpt":0.3090486069677208,"score_spread":0.27080663165406776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244822879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913798,0.00015025535,0.000020613745,0.0011883716,0.0004550051,0.005984289,0.00035749335,0.00016166504,0.00030253688],"genre_scores_gemma":[0.9977585,0.00015956625,0.00015088433,0.00084924366,0.000076132004,0.00052195904,0.000024415147,0.00007480101,0.00038449085],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99426264,0.0013821194,0.00068785297,0.0023433405,0.0005562554,0.0007677866],"domain_scores_gemma":[0.9974487,0.0008865889,0.0003472212,0.00077270914,0.00018105602,0.0003637624],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006517343,0.0008254756,0.000845539,0.00062628597,0.00030876568,0.00028293312,0.00071979995,0.00030174083,0.0001290445],"category_scores_gemma":[0.0015800704,0.0006669431,0.00010124986,0.0007504864,0.001281373,0.00041369683,0.002676786,0.0013166211,0.00015926831],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.034719594,0.00090775365,0.21881224,0.0005325049,0.0004549203,0.0007641152,0.017628718,0.00010851839,0.72403467,0.0004849221,0.000111662695,0.0014403847],"study_design_scores_gemma":[0.0046986076,0.0003890003,0.9010623,0.0007401973,0.000041038867,0.00009812087,0.00032144267,0.00011866066,0.09019805,0.0014818652,0.00008317198,0.00076754024],"about_ca_topic_score_codex":0.00028238675,"about_ca_topic_score_gemma":0.0000476246,"teacher_disagreement_score":0.6822501,"about_ca_system_score_codex":0.00011861956,"about_ca_system_score_gemma":0.0001478919,"threshold_uncertainty_score":0.9995782},"labels":[],"label_agreement":null},{"id":"W4249094017","doi":"10.22215/etd/2011-09658","title":"Stressor and cytokine interactions : implications in depressive-like pathology","year":2011,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Stressor; Psychology; Clinical psychology","score_opus":0.03275036938039249,"score_gpt":0.30362672003787633,"score_spread":0.27087635065748383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249094017","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8918075,0.000097710086,0.000041926174,0.0001808843,0.00046953745,0.0003567466,0.00007053993,0.00009194645,0.10688318],"genre_scores_gemma":[0.97520655,0.0003125651,0.00009353539,0.00044222985,0.000023716892,0.00017349562,0.00014237214,0.00002867427,0.02357686],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998923,0.00006473753,0.00023228444,0.0005091457,0.00006598604,0.00020486994],"domain_scores_gemma":[0.9993685,0.00016066231,0.00012469063,0.00026270022,0.000025939904,0.00005751526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000024947336,0.00017979273,0.00018443466,0.00027403413,0.00009240717,0.000031362695,0.00020071345,0.0001474631,0.00046574883],"category_scores_gemma":[0.00017838365,0.00016789472,0.000042753505,0.00019749964,0.000059161233,0.00013332645,0.000035712063,0.00029663084,0.00005028741],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018773913,0.0006789783,0.0038177145,0.00013361304,0.000015136497,0.00007886411,0.0034573975,0.0000033412734,0.8912799,0.04554393,0.0030996166,0.051703777],"study_design_scores_gemma":[0.0015004061,0.00010936049,0.6936306,0.00015260372,0.00003903072,0.00012713857,0.0018459159,0.00005657528,0.27265245,0.01552138,0.013448088,0.000916438],"about_ca_topic_score_codex":0.00010197597,"about_ca_topic_score_gemma":0.005383628,"teacher_disagreement_score":0.6898129,"about_ca_system_score_codex":0.0000140603415,"about_ca_system_score_gemma":0.000039378083,"threshold_uncertainty_score":0.6846548},"labels":[],"label_agreement":null},{"id":"W4249251460","doi":"10.1093/schbul/sbz018.418","title":"F6. CEREBROSPINAL FLUID MARKERS OF INFLAMMATION AND INFECTIONS IN SCHIZOPHRENIA AND AFFECTIVE DISORDERS: A SYSTEMATIC REVIEW AND META-ANALYSIS","year":2019,"lang":"en","type":"review","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Saint Vincent University; Dalhousie University","funders":"","keywords":"Meta-analysis; Schizophrenia (object-oriented programming); Inflammation; Cerebrospinal fluid; Medicine; Psychology; Psychiatry; Clinical psychology; Immunology; Internal medicine","score_opus":0.033100424280103166,"score_gpt":0.29128513643093595,"score_spread":0.2581847121508328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249251460","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025421803,0.99404,0.00002332646,0.00027944436,0.00003436331,0.004678263,0.0001044864,0.000057451405,0.0005284644],"genre_scores_gemma":[0.0014969725,0.99698585,0.00021708362,0.000070286085,0.000013096452,0.00064775825,0.000016128626,0.00008406362,0.00046874426],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9954271,0.0014889647,0.0012659929,0.0011251473,0.00034297947,0.0003498571],"domain_scores_gemma":[0.9970297,0.0010880074,0.0010326131,0.0006690211,0.000038588634,0.0001420279],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00075962325,0.0007582141,0.005908631,0.0011156476,0.00011650761,0.00011381589,0.00027662388,0.00028898727,0.00045411833],"category_scores_gemma":[0.001449158,0.00057816936,0.0009692223,0.0016413729,0.00033655483,0.000120116514,0.00025683458,0.0004712655,0.000075013646],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009602531,0.00010833975,0.000008281406,0.9693742,0.012981926,0.000005001712,0.000065194654,0.0000024844305,0.000017295259,0.0017941935,0.00017034778,0.015376725],"study_design_scores_gemma":[0.0031389385,0.00065432256,0.00018605741,0.0810502,0.8771514,0.00021481936,0.00007993185,0.00006846458,0.000018795474,0.0005810585,0.034461915,0.0023940857],"about_ca_topic_score_codex":0.00007973241,"about_ca_topic_score_gemma":0.0002555665,"teacher_disagreement_score":0.88832396,"about_ca_system_score_codex":0.000041995074,"about_ca_system_score_gemma":0.00009136716,"threshold_uncertainty_score":0.999667},"labels":[],"label_agreement":null},{"id":"W4252442113","doi":"10.1002/da.22801","title":"Issue Information","year":2019,"lang":"en","type":"paratext","venue":"Depression and Anxiety","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Dell Medical School, University of Texas at Austin; Audrey and Theodor Geisel School of Medicine at Dartmouth; School of Medicine, Emory University; University of California, San Diego; School of Medicine, Stanford University; University of Illinois at Urbana-Champaign; Rijksuniversiteit Groningen; Dalhousie University; New York State Psychiatric Institute; McMaster University; Rush University; University of Louisville; McLean Hospital; University of South Florida; Brown University; Emory University; Dartmouth College","keywords":"Citation; Mental health; Information retrieval; World Wide Web; Computer science; Psychology; Library science; Internet privacy; Psychiatry","score_opus":0.01203667198015515,"score_gpt":0.25798872949926593,"score_spread":0.24595205751911078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4252442113","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007860834,0.0013956577,0.00033931207,0.00044059908,0.006775725,0.00058149383,0.00023678597,0.000109034,0.9822606],"genre_scores_gemma":[0.25434482,0.020924844,0.00010009438,0.016645119,0.0006075003,0.000048042864,0.0004009228,0.00005948661,0.7068692],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990651,0.000047545844,0.00017978945,0.00029800218,0.00021575038,0.00019381646],"domain_scores_gemma":[0.9994887,0.000043434116,0.00012763924,0.00024518635,0.000016228445,0.00007880639],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000044900826,0.0001951026,0.00019028946,0.00008474576,0.00011602031,0.00013159194,0.00018407723,0.0002692741,0.0038898669],"category_scores_gemma":[0.00007239237,0.00015153423,0.0000620439,0.00010732128,0.000052797583,0.00035785805,0.0001369546,0.0002817868,0.029769834],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001825215,0.00001503313,0.000029326186,0.00013068627,0.0000016415876,2.8578924e-7,0.00018796396,0.000012735144,0.007883135,0.000050209746,0.907228,0.08444276],"study_design_scores_gemma":[0.00035714902,0.000012892794,0.0001779983,0.000077545745,0.0000020923942,0.000006411065,0.00004816974,0.00017617032,0.02803932,0.000017420512,0.97088355,0.00020126051],"about_ca_topic_score_codex":0.000008267766,"about_ca_topic_score_gemma":2.838989e-7,"teacher_disagreement_score":0.2753914,"about_ca_system_score_codex":0.000008528866,"about_ca_system_score_gemma":0.000033309225,"threshold_uncertainty_score":0.9970207},"labels":[],"label_agreement":null},{"id":"W4252599792","doi":"10.21203/rs.3.rs-31118/v1","title":"Ibrutinib alleviated LPS-induced neuroinflammation and synaptic defects in a mouse model of depression","year":2020,"lang":"en","type":"preprint","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Shenzhen-Hong Kong Institute of Brain Science","keywords":"Neuroinflammation; Ibrutinib; Depression (economics); Neuroscience; Pharmacology; Medicine; Psychology; Internal medicine; Inflammation","score_opus":0.062250640505511406,"score_gpt":0.2733852653522201,"score_spread":0.21113462484670867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4252599792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99641836,0.000024280396,0.0003558901,0.00020556005,0.00006429167,0.0007685374,0.000013164201,0.00014947678,0.0020004504],"genre_scores_gemma":[0.9992079,0.00009034535,0.00029417267,0.00024068153,0.000007900157,0.000026521739,0.0000075495964,0.000031234697,0.000093692135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981695,0.00016577568,0.00041209732,0.00077292026,0.00026399014,0.00021574061],"domain_scores_gemma":[0.9991283,0.00016724232,0.00023012428,0.00035476085,0.000021499252,0.00009808852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009475261,0.0002567539,0.00036896009,0.00018770316,0.000026967182,0.000044923727,0.00028785795,0.00024103095,0.000028710976],"category_scores_gemma":[0.0006226534,0.00023782178,0.00007564722,0.00016534605,0.000045672,0.000103984006,0.0006607868,0.00045359938,0.000013025718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000809673,0.000055422905,0.00036095217,0.00027838218,0.0000038176186,0.000005853572,0.000331965,0.0083000455,0.989674,0.00046083462,0.000013395698,0.00043437007],"study_design_scores_gemma":[0.0006429925,0.000039140275,0.0010681795,0.00009010197,0.0000050910426,0.0000013185315,0.000025032808,0.38387802,0.6116441,0.0024120442,0.0000010734786,0.00019291164],"about_ca_topic_score_codex":0.0000475545,"about_ca_topic_score_gemma":0.000039582443,"teacher_disagreement_score":0.3780299,"about_ca_system_score_codex":0.000019034816,"about_ca_system_score_gemma":0.00008941596,"threshold_uncertainty_score":0.96980906},"labels":[],"label_agreement":null},{"id":"W4253627710","doi":"10.22215/etd/2013-09899","title":"Interactive Effects of a Social Stressor and Interleukin-6 Injection on Anxiety-Related Behaviors and Expression of Pro-Inflammatory Factors in Male CD-1 Mice","year":2013,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Social defeat; Stressor; Neurochemical; Exacerbation; Anxiety; Cytokine; Psychology; Interleukin; Endocrine system; Depression (economics); Neuroinflammation; Social stress; Proinflammatory cytokine; Neuroscience; Amygdala; Inflammation; Medicine; Hormone; Immunology; Internal medicine; Psychiatry","score_opus":0.006921028851120519,"score_gpt":0.25581649923003497,"score_spread":0.24889547037891444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253627710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976155,0.00003376752,6.9859465e-7,0.000004737531,0.00030550783,0.00091168657,0.000013350231,0.00002818981,0.001086562],"genre_scores_gemma":[0.9981573,0.000046888952,0.00000816115,0.000010669186,0.00000813026,0.000059038848,0.000039141276,0.00003035847,0.0016403022],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985513,0.00017089989,0.00040920798,0.00046944324,0.00022776648,0.00017138408],"domain_scores_gemma":[0.99904287,0.00029202388,0.0004694207,0.00010302959,0.000046892095,0.000045749854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000050605293,0.000284208,0.0003797324,0.00040576162,0.00005615777,0.00002454918,0.0001179477,0.0003550756,0.00007622809],"category_scores_gemma":[0.00022052419,0.0002420999,0.00007124603,0.00017808535,0.00011481244,0.0002564743,0.000042255764,0.00039305192,0.0000019810896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033787653,0.00022415431,0.003389992,0.00066516636,0.0000070185265,0.0000027971143,0.014162403,9.475796e-7,0.9789016,0.00007692843,0.00006201557,0.0021690547],"study_design_scores_gemma":[0.0007755071,0.00027852444,0.15457205,0.00064376876,0.000015251899,0.0000019388149,0.0053010206,0.000013562429,0.8381747,0.000040432962,0.0000045222346,0.00017869462],"about_ca_topic_score_codex":0.00016943444,"about_ca_topic_score_gemma":0.00023118984,"teacher_disagreement_score":0.15118206,"about_ca_system_score_codex":0.00004337744,"about_ca_system_score_gemma":0.000034753248,"threshold_uncertainty_score":0.98725474},"labels":[],"label_agreement":null},{"id":"W4255027732","doi":"10.21203/rs.3.rs-275074/v1","title":"Targeted Metabolomics Identifies High Performing Diagnostic and Prognostic Biomarkers for COVID-19","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"Consejo Nacional de Ciencia y Tecnología","keywords":"Medicine; Internal medicine; Receiver operating characteristic; Area under the curve; Metabolomics; Metabolite; Coronavirus disease 2019 (COVID-19); Disease; Real-time polymerase chain reaction; Gastroenterology; Bioinformatics; Biology; Infectious disease (medical specialty)","score_opus":0.09138133294687671,"score_gpt":0.38900328362529885,"score_spread":0.2976219506784221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4255027732","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848215,0.0057203174,0.0011483664,0.0026223648,0.0007118744,0.004064251,0.0006091572,0.0001930284,0.000109129454],"genre_scores_gemma":[0.9932943,0.003378259,0.0007124159,0.00033739908,0.000153655,0.0014322093,0.00028600133,0.000080160404,0.00032559034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99500453,0.0008963153,0.00043679672,0.0015420506,0.0010621018,0.0010581835],"domain_scores_gemma":[0.98489183,0.013367516,0.00014203029,0.0007114663,0.00033960224,0.00054757606],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017019522,0.00038875669,0.00051645836,0.00065485074,0.0008928424,0.0009810709,0.000731426,0.00037780032,0.00018544884],"category_scores_gemma":[0.09582723,0.00037609253,0.00022029717,0.00071972125,0.0007844167,0.00022170675,0.0017755855,0.001046222,0.00001699191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028983,0.003667093,0.052213136,0.10454478,0.0015048232,0.003484632,0.026197437,0.0036042084,0.64914745,0.024027813,0.060957123,0.06775322],"study_design_scores_gemma":[0.013147574,0.001906723,0.11862416,0.0055756764,0.0005034546,0.00024407826,0.038134016,0.022496978,0.6523851,0.0976231,0.042950474,0.006408628],"about_ca_topic_score_codex":0.00032539718,"about_ca_topic_score_gemma":0.00015614933,"teacher_disagreement_score":0.0989691,"about_ca_system_score_codex":0.00021176251,"about_ca_system_score_gemma":0.0013226577,"threshold_uncertainty_score":0.9998691},"labels":[],"label_agreement":null},{"id":"W4256344135","doi":"10.22215/etd/2006-08293","title":"Behavioral, immunological and central monoaminergic alterations induced by the viral imitator, poly I:C: augmentation by a psychosocial stressor","year":2006,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Stressor; Psychosocial; Psychology; Monoaminergic; Developmental psychology; Clinical psychology; Medicine; Psychiatry; Internal medicine","score_opus":0.023900201079109142,"score_gpt":0.3025195990240183,"score_spread":0.2786193979449092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4256344135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947354,0.0007752691,0.000022478123,0.0005669823,0.0006003137,0.0006001616,0.00030212622,0.00011502462,0.002282213],"genre_scores_gemma":[0.9875124,0.00016868656,0.00003160987,0.0004982059,0.00007710384,0.0001552918,0.0020630471,0.000038054142,0.0094555775],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980666,0.00017213059,0.0003810391,0.0005959502,0.00035474432,0.00042953063],"domain_scores_gemma":[0.9993794,0.000102598875,0.00021762123,0.00019710408,0.000028397222,0.00007490822],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00003423103,0.00035844595,0.00023158766,0.00007393568,0.0005569528,0.0003318778,0.00030576222,0.00033381968,0.0001481783],"category_scores_gemma":[0.000041336512,0.00026648198,0.000108300046,0.00019958922,0.00012770834,0.0002399677,0.000022390188,0.00041233675,0.00001288741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011542129,0.00046469807,0.00004113958,0.000008931573,0.000010204999,0.0000019845143,0.000799742,4.947863e-7,0.94493484,0.0011358857,0.04102609,0.011460575],"study_design_scores_gemma":[0.004903645,0.0011033749,0.033493802,0.000060925002,0.0001676523,0.0000107100595,0.008372495,0.00020652649,0.9418707,0.0017507394,0.0062816935,0.0017777499],"about_ca_topic_score_codex":0.00054641446,"about_ca_topic_score_gemma":0.00045963103,"teacher_disagreement_score":0.034744397,"about_ca_system_score_codex":0.000056743604,"about_ca_system_score_gemma":0.0000552844,"threshold_uncertainty_score":0.9999787},"labels":[],"label_agreement":null},{"id":"W4280551526","doi":"10.3389/fpsyt.2022.844176","title":"The Impact of Cognitive Behavioral Therapy on Peripheral Interleukin-6 Levels in Depression: A Systematic Review and Meta-Analysis","year":2022,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Southwest University; Ministry of Education, India","keywords":"Depression (economics); Major depressive disorder; Meta-analysis; Cognitive behavioral therapy; PsycINFO; Clinical psychology; Cochrane Library; Peripheral; Medicine; Internal medicine; Psychology; Subgroup analysis; Psychosocial; Web of science; Psychiatry; Cognition; MEDLINE","score_opus":0.11905181264039567,"score_gpt":0.40281848945496257,"score_spread":0.2837666768145669,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280551526","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011790101,0.9956813,0.000020693677,0.00003435186,0.000638734,0.0030868899,0.0002734696,0.000014301917,0.00013235303],"genre_scores_gemma":[0.001201651,0.997021,0.000065294844,0.00032702184,0.000010852327,0.0011738486,0.000015023897,0.000045536905,0.00013974973],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9950445,0.0022079297,0.0012586406,0.00073929544,0.00040241305,0.00034716446],"domain_scores_gemma":[0.9977682,0.00056051585,0.00092194317,0.0006672742,0.000014667986,0.00006737413],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007281439,0.0005692588,0.005219966,0.0005978525,0.00012623436,0.000059434795,0.0007805883,0.00014800057,0.00037672647],"category_scores_gemma":[0.0002563542,0.0002996,0.0029811964,0.0019745533,0.0001877258,0.000083910345,0.00011008697,0.00074706186,0.0000015387894],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035077968,0.00389716,0.0011531081,0.6925339,0.10228235,0.000090976144,0.0026635658,0.0000217602,4.7730447e-7,0.00017971276,0.014759379,0.1820668],"study_design_scores_gemma":[0.003768388,0.0022668855,0.00072895596,0.17239691,0.79482204,0.00013539981,0.0028510352,0.00006331631,0.0000028055806,0.001152437,0.018485561,0.0033262894],"about_ca_topic_score_codex":0.000044815813,"about_ca_topic_score_gemma":0.00004515434,"teacher_disagreement_score":0.69253963,"about_ca_system_score_codex":0.00015810337,"about_ca_system_score_gemma":0.00023306147,"threshold_uncertainty_score":0.99994564},"labels":[],"label_agreement":null},{"id":"W4280623306","doi":"10.1017/s0033291722000174","title":"Applying dimensional psychopathology: transdiagnostic prediction of executive cognition using brain connectivity and inflammatory biomarkers","year":2022,"lang":"en","type":"article","venue":"Psychological Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Fractional anisotropy; Bipolar disorder; Cognition; Psychology; Wisconsin Card Sorting Test; Schizophrenia (object-oriented programming); Executive dysfunction; Neuroscience; Neuropsychology; Functional magnetic resonance imaging; Major depressive disorder; Medicine; Psychopathology; Diffusion MRI; Clinical psychology; Psychiatry; Magnetic resonance imaging","score_opus":0.056627469969382255,"score_gpt":0.3158602322754132,"score_spread":0.259232762306031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280623306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951737,0.00019752939,0.0009076565,0.0012581106,0.0005305576,0.0007078412,0.000072552415,0.00007830461,0.001073736],"genre_scores_gemma":[0.9967209,0.000028963412,0.000099735356,0.0028900527,0.000054149306,0.00017548034,0.000011098712,0.000011035253,0.00000856226],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980727,0.0005329257,0.00030911886,0.0005194221,0.00034919768,0.00021665664],"domain_scores_gemma":[0.9981687,0.001427846,0.00014843266,0.00013925874,0.00002333522,0.00009243861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055073964,0.00014875439,0.00024894447,0.00017632834,0.0002668518,0.0000036066167,0.000115250805,0.00007161961,0.00033950226],"category_scores_gemma":[0.0014213114,0.00012378262,0.000043023138,0.00039326536,0.0008171335,0.000071185284,0.000055533626,0.0002865283,0.000001430191],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055319123,0.0003416676,0.0015324934,0.000026299718,0.000011700995,0.000064825275,0.00045187504,0.00005373448,0.98382133,0.0007074199,0.00074184843,0.011693598],"study_design_scores_gemma":[0.02257685,0.008936003,0.8743725,0.00040913754,0.00020131597,0.002701776,0.004710009,0.0067525883,0.033544295,0.043094043,0.0017282532,0.0009732339],"about_ca_topic_score_codex":0.0000046062223,"about_ca_topic_score_gemma":5.325164e-7,"teacher_disagreement_score":0.95027703,"about_ca_system_score_codex":0.000024860588,"about_ca_system_score_gemma":0.000006644829,"threshold_uncertainty_score":0.5047709},"labels":[],"label_agreement":null},{"id":"W4281288712","doi":"10.3410/f.741585528.793592349","title":"Faculty Opinions recommendation of Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity.","year":2022,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Aryl hydrocarbon receptor; Immunity; Tryptophan; Aryl; Chemistry; Receptor; Microbiology; Biology; Biochemistry; Immunology; Immune system; Organic chemistry; Gene","score_opus":0.02631780068671514,"score_gpt":0.31758219926190634,"score_spread":0.2912643985751912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281288712","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006624939,0.0006184167,0.0000019174947,0.10934424,0.0013004299,0.002402367,0.8855881,0.000058201564,0.000023820097],"genre_scores_gemma":[0.00095029763,0.0003917624,0.000075799726,0.011463818,0.00012649239,0.00054670364,0.98611313,0.000052586398,0.0002794367],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9927654,0.002037922,0.0018633624,0.0010558162,0.0016174166,0.00066005415],"domain_scores_gemma":[0.9941286,0.00066853117,0.0019208777,0.0017351493,0.0012762131,0.0002706268],"candidate_categories":["metaresearch","metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001661805,0.00074561633,0.0013214602,0.0006384633,0.00057560456,0.00024496458,0.0037160763,0.00037285726,0.0028063864],"category_scores_gemma":[0.018607639,0.00048226645,0.0007004316,0.004777478,0.00053458527,0.00041963978,0.0013757802,0.002001705,0.00003304309],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052112504,0.00087282155,0.000004135056,0.0015267158,0.00007313211,0.0000011127711,0.00035743555,8.8579594e-7,0.009267614,0.00006783213,0.98742217,0.0003540409],"study_design_scores_gemma":[0.0010964455,0.0001363937,0.0024390456,0.0028397662,0.00007424525,0.000023459164,0.0001373723,0.0000056308277,0.011414799,0.000019602574,0.98134196,0.00047126669],"about_ca_topic_score_codex":0.00021512891,"about_ca_topic_score_gemma":0.000016833621,"teacher_disagreement_score":0.100524984,"about_ca_system_score_codex":0.00020940157,"about_ca_system_score_gemma":0.00049557735,"threshold_uncertainty_score":0.9997629},"labels":[],"label_agreement":null},{"id":"W4281392218","doi":"10.1016/j.psyneuen.2022.105806","title":"Inflammatory markers and incident depression: Evidence in a population-based prospective study","year":2022,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Depression (economics); Confounding; Medicine; Prospective cohort study; Internal medicine; Longitudinal study; Population; C-reactive protein; Inflammation; Environmental health; Pathology","score_opus":0.03217986953609705,"score_gpt":0.2994009097558774,"score_spread":0.2672210402197804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281392218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971705,0.00017444987,0.0000070651913,0.000763095,0.00048828684,0.0010444996,0.0000037501486,0.00010633414,0.00024200216],"genre_scores_gemma":[0.9979772,0.000024505525,0.00001779171,0.0012971283,0.00001673748,0.0005822753,7.205249e-7,0.000021262891,0.00006240149],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9973521,0.000858173,0.00029856394,0.0007894228,0.00032263744,0.00037910236],"domain_scores_gemma":[0.99894595,0.0005093339,0.00011564612,0.000351532,0.000011653522,0.00006589541],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000098491255,0.00017037262,0.00019185583,0.0003402107,0.00028055173,0.000025794696,0.00032588033,0.000014803404,0.00019343846],"category_scores_gemma":[0.0005482149,0.00017988589,0.00003449449,0.00047706527,0.00008887753,0.00014168676,0.0002754036,0.0004138578,0.00001103866],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005242205,0.00039855475,0.9919553,0.000009838123,0.000002464487,0.0004941695,0.0003067652,0.00029848015,0.0046653645,0.00015806136,0.00012690353,0.0010598688],"study_design_scores_gemma":[0.0017178922,0.00041867665,0.99554545,0.000008417168,0.0000034759362,0.00012322575,0.0004338775,0.0002561922,0.0006350436,0.00046854152,0.00022765518,0.00016154788],"about_ca_topic_score_codex":0.000121103054,"about_ca_topic_score_gemma":0.00016765665,"teacher_disagreement_score":0.004030321,"about_ca_system_score_codex":0.00008713979,"about_ca_system_score_gemma":0.000041040275,"threshold_uncertainty_score":0.73355335},"labels":[],"label_agreement":null},{"id":"W4281648814","doi":"10.3390/ijms23116300","title":"An Emerging Cross-Species Marker for Organismal Health: Tryptophan-Kynurenine Pathway","year":2022,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Northern British Columbia; University of Manitoba; Environment and Climate Change Canada; McMaster University","funders":"","keywords":"Kynurenine pathway; Kynurenine; Biology; Tryptophan; Vertebrate; Metabolic pathway; Xenobiotic; Metabolism; Biochemistry; Amino acid; Enzyme; Gene","score_opus":0.10340527058977313,"score_gpt":0.4070833073872577,"score_spread":0.30367803679748456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281648814","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012691045,0.98829323,0.0034929074,0.0007772239,0.004725408,0.00047022646,0.00021378706,0.000035969555,0.00072216906],"genre_scores_gemma":[0.00259218,0.99336797,0.0018435539,0.0012716475,0.00055405445,0.000031205876,0.000021501202,0.00005419629,0.00026371444],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9955924,0.00044076462,0.0011327815,0.0005805667,0.0018315616,0.00042192356],"domain_scores_gemma":[0.9973046,0.00048005677,0.0016232381,0.00021033022,0.00019021459,0.0001915711],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014354585,0.00034611244,0.00081200665,0.0007440518,0.00045225624,0.0006084696,0.0032654798,0.00009221887,0.0008705954],"category_scores_gemma":[0.0009204181,0.00027434237,0.00072644727,0.0006266701,0.0004236963,0.0005232269,0.00020556491,0.00044113808,0.0000068086865],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050014707,0.00026906445,0.0000055181467,0.00041801287,0.00008928731,0.0003046067,0.00026367,0.00016596899,0.0042616436,0.008326806,0.00041141806,0.985434],"study_design_scores_gemma":[0.00041899597,0.0005579471,0.000012269697,0.0005560886,0.000019215831,0.00065026904,0.00013564184,0.00004756023,0.0018056271,0.0007893393,0.9947132,0.00029384912],"about_ca_topic_score_codex":0.0000039266833,"about_ca_topic_score_gemma":0.0000021136289,"teacher_disagreement_score":0.9943018,"about_ca_system_score_codex":0.00021535666,"about_ca_system_score_gemma":0.001474796,"threshold_uncertainty_score":0.99997085},"labels":[],"label_agreement":null},{"id":"W4281652956","doi":"10.1016/j.ejpsy.2022.05.001","title":"Activity of energy, glutamate, and glutathione metabolism enzymes in blood cells of elderly patients with depression","year":2022,"lang":"en","type":"article","venue":"The European Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Manitoba Health Research Council","keywords":"Depression (economics); Glutathione; Glutathione reductase; Anxiety; Medicine; Glutamate receptor; Internal medicine; Endocrinology; Psychiatry; Enzyme; Biology; Biochemistry; Glutathione peroxidase","score_opus":0.006613931192530249,"score_gpt":0.1956522652254636,"score_spread":0.18903833403293335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281652956","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975356,0.00091826794,0.00005559074,0.00017385742,0.00034753873,0.00006327154,0.000019358016,0.0000045715706,0.0008819354],"genre_scores_gemma":[0.9994612,0.00008474795,0.00025859245,0.00011127369,0.000041860483,5.266865e-7,1.9682608e-7,0.00001873012,0.0000228984],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99790865,0.0011039936,0.00034059366,0.00013721983,0.00037886848,0.00013067931],"domain_scores_gemma":[0.99900913,0.000087292625,0.00065091276,0.00017467148,0.000031195315,0.00004676864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005286662,0.00010774251,0.00021027951,0.00014074527,0.00009718546,0.000010389654,0.00037037075,0.000009664823,0.000021311305],"category_scores_gemma":[0.000030738458,0.000067954454,0.00006117868,0.00027934683,0.00012062629,0.00012335558,0.00013250645,0.0002577655,3.0556726e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042165304,0.0058415374,0.066433534,0.00016518493,0.00014081954,0.000091263166,0.0033952198,0.0023217476,0.8816185,0.0038827413,0.0013001773,0.030592747],"study_design_scores_gemma":[0.008479739,0.0019917174,0.6371627,0.00015935929,0.000105583196,0.000099564655,0.0006432118,0.000022968123,0.34948877,0.0011185913,0.0004633331,0.00026447902],"about_ca_topic_score_codex":0.000009823696,"about_ca_topic_score_gemma":0.000006836736,"teacher_disagreement_score":0.57072914,"about_ca_system_score_codex":0.000004049366,"about_ca_system_score_gemma":0.00004899241,"threshold_uncertainty_score":0.27711022},"labels":[],"label_agreement":null},{"id":"W4281702791","doi":"10.1503/jpn.210124","title":"The functional and structural associations of aberrant microglial activity in major depressive disorder","year":2022,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Ontario Shores Centre for Mental Health Sciences; London Health Sciences Centre; University of Toronto; Lawson Health Research Institute; Western University","funders":"Department of Psychiatry, University of Toronto; London Health Sciences Centre; Lawson Health Research Institute","keywords":"Major depressive disorder; Anterior cingulate cortex; Insula; Psychology; Diffusion MRI; Neuroscience; Fractional anisotropy; Default mode network; Medicine; Functional connectivity; White matter; Internal medicine; Magnetic resonance imaging; Cognition","score_opus":0.01981583377533144,"score_gpt":0.2662952708359199,"score_spread":0.24647943706058847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281702791","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99515766,0.0003810157,0.000047041816,0.0027957163,0.0014717651,0.000075094904,0.000031127798,0.0000027137687,0.000037860686],"genre_scores_gemma":[0.9994131,0.0000916284,0.000031538417,0.00036938372,0.00003883878,0.0000023559953,6.9591614e-8,0.0000037564114,0.00004937071],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998893,0.00019982731,0.00023486935,0.00017084932,0.00034634044,0.00015506418],"domain_scores_gemma":[0.99924034,0.00025796908,0.0003593221,0.00007368621,0.000020113082,0.000048553575],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027720176,0.00007468283,0.000115727256,0.00008738264,0.0007396373,0.000045650468,0.00021307735,0.000017113865,0.000009533659],"category_scores_gemma":[0.00028740283,0.000053010554,0.0000489833,0.00031226387,0.0002905483,0.00023530223,0.00010698472,0.0003241053,6.424725e-8],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003266026,0.00021149578,0.19647633,0.000011978554,0.0000033706713,0.000010222019,0.0003138413,0.00062787207,0.7959789,0.0032578602,0.00023450478,0.0025470096],"study_design_scores_gemma":[0.0012013556,0.0002821308,0.9836959,0.0000056472186,0.0000068796694,0.0002578888,0.0002784195,0.00068680826,0.0089165,0.004240824,0.0003417123,0.000085902866],"about_ca_topic_score_codex":0.000011302598,"about_ca_topic_score_gemma":0.00006316156,"teacher_disagreement_score":0.7872196,"about_ca_system_score_codex":0.000013113092,"about_ca_system_score_gemma":0.0001161017,"threshold_uncertainty_score":0.5688767},"labels":[],"label_agreement":null},{"id":"W4282837697","doi":"10.3390/ph15060742","title":"Longitudinal Consumption of Ergothioneine Reduces Oxidative Stress and Amyloid Plaques and Restores Glucose Metabolism in the 5XFAD Mouse Model of Alzheimer’s Disease","year":2022,"lang":"en","type":"article","venue":"Pharmaceuticals","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; National Institute on Aging; National Institutes of Health","keywords":"Ergothioneine; Oxidative stress; Disease; Carbohydrate metabolism; Oxidative metabolism; Amyloid (mycology); Metabolism; Amyloid β; Medicine; Pharmacology; Internal medicine; Chemistry; Biochemistry; Pathology; Antioxidant","score_opus":0.12597170826788182,"score_gpt":0.3628698959005745,"score_spread":0.23689818763269269,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282837697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99177486,0.0067265206,0.000017730164,0.0006411444,0.00003147603,0.00034483508,0.00039829302,0.00001595623,0.000049180067],"genre_scores_gemma":[0.9969384,0.002563975,0.00007150963,0.00033178218,0.000010341469,0.000057286925,0.0000045878296,0.000009656491,0.000012466857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851257,0.0004159894,0.00025936987,0.0002990589,0.00033906542,0.00017395148],"domain_scores_gemma":[0.9992439,0.00038060205,0.00011825083,0.00014853074,0.00001970536,0.000088989815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003104388,0.00012472723,0.00020485828,0.00011840076,0.00011980928,0.000018623057,0.00019638658,0.000018066627,0.000056602545],"category_scores_gemma":[0.0002315153,0.00009741094,0.000034478126,0.0001585114,0.0005371516,0.00016141612,0.0001781978,0.00018798876,4.893635e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072819646,0.00058653246,0.0027986004,0.00009369145,0.000025402427,0.000009487848,0.0027341654,0.0010504257,0.98092973,0.0097049745,0.00008366056,0.0012551439],"study_design_scores_gemma":[0.0010011931,0.000043487365,0.013566531,0.000016545242,0.000080284204,0.0000029605114,0.00043588146,0.009739402,0.9732995,0.0016139923,0.00007270396,0.00012751536],"about_ca_topic_score_codex":0.00001660168,"about_ca_topic_score_gemma":0.0000045600036,"teacher_disagreement_score":0.01076793,"about_ca_system_score_codex":0.000007877875,"about_ca_system_score_gemma":0.000031858104,"threshold_uncertainty_score":0.3972303},"labels":[],"label_agreement":null},{"id":"W4283456040","doi":"10.21203/rs.3.rs-1759648/v1","title":"Bibliometric and Visual Analysis of Research on the Links between the Microbiome-Gut-Brain axis and Depression","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"China Academy of Chinese Medical Sciences; National Natural Science Foundation of China; National Key Research and Development Program of China; University College Cork; McMaster University","keywords":"Depression (economics); Citation; Microbiome; Anxiety; Gut microbiome; Medicine; Psychology; Psychiatry; Bioinformatics; Biology; Library science; Computer science","score_opus":0.1737048388415651,"score_gpt":0.4724854897595097,"score_spread":0.2987806509179446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283456040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9873075,0.0019885094,0.00001558391,0.0072727157,0.00006887802,0.0015083115,0.00049629953,0.000037951544,0.0013042542],"genre_scores_gemma":[0.9966461,0.0021498897,0.000008122694,0.0002005988,0.00010809,0.00023270227,0.00005327198,0.000041337185,0.00055990624],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.98702717,0.0068653063,0.00045100073,0.0013609879,0.0033630475,0.000932479],"domain_scores_gemma":[0.971134,0.026884582,0.00016199729,0.0011977298,0.00040985778,0.00021181763],"candidate_categories":["metaresearch","bibliometrics","sts","research_integrity"],"consensus_categories":["bibliometrics"],"category_scores_codex":[0.011509008,0.00028658286,0.0005341157,0.0648767,0.001635415,0.0005538982,0.0016545656,0.00043057796,0.0005898057],"category_scores_gemma":[0.011238356,0.00016829907,0.00023771242,0.1381179,0.0020017335,0.000076085555,0.006770358,0.005820064,0.000013794434],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016778426,0.0025240616,0.3359099,0.005131726,0.0025699276,0.00025144796,0.01414791,0.00085094024,0.27509046,0.0041782223,0.09647054,0.261197],"study_design_scores_gemma":[0.0007550374,0.0009621661,0.9354809,0.0004330084,0.00010950538,0.000003521144,0.006776528,0.002295145,0.035756353,0.0028434307,0.0140620265,0.00052236515],"about_ca_topic_score_codex":0.00046844463,"about_ca_topic_score_gemma":0.000035888886,"teacher_disagreement_score":0.599571,"about_ca_system_score_codex":0.00012126361,"about_ca_system_score_gemma":0.00025086335,"threshold_uncertainty_score":0.9996643},"labels":[{"model":"gemma","categories":["bibliometrics"],"domain":null,"study_design":"observational","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":["bibliometrics"],"domain":null,"study_design":"design_other","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"split"},{"id":"W4283520930","doi":"10.25011/cim.v45i2.38096","title":"Metabolomics and Cytokine Analysis for Identification of Schizophrenia with Auditory Hallucination","year":2022,"lang":"en","type":"article","venue":"Clinical and investigative medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Natural Science Foundation of Xinjiang","keywords":"Positive and Negative Syndrome Scale; Schizophrenia (object-oriented programming); Biomarker; Internal medicine; Psychosis; Young Mania Rating Scale; Psychology; Clinical Global Impression; Medicine; Psychiatry; Chemistry; Bipolar disorder; Biochemistry; Pathology","score_opus":0.1152703005682915,"score_gpt":0.32972300983743236,"score_spread":0.21445270926914084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283520930","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99042445,0.00015647644,0.0033496364,0.005527013,0.0001639435,0.0002583063,0.00004807336,0.000015948108,0.000056162426],"genre_scores_gemma":[0.99815583,0.00009533427,0.00059233926,0.0008289023,0.000103392114,0.00004152477,0.000022443717,0.00000626015,0.0001539784],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99877256,0.000190418,0.0004252986,0.00033851145,0.00019055337,0.00008265692],"domain_scores_gemma":[0.99895227,0.00049060996,0.00029029683,0.00012158481,0.000058658312,0.000086571985],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0006086362,0.00008520224,0.00031590415,0.00014080774,0.00016280434,0.000005559353,0.00008826889,0.000025308691,0.000027743888],"category_scores_gemma":[0.0021439064,0.000060331822,0.000037003214,0.0005351251,0.004036684,0.00008817754,0.000053090902,0.00013311078,2.298958e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015445179,0.00055758265,0.06282984,0.00023085969,0.0005924073,0.0000058971686,0.002938692,0.00070965925,0.7588088,0.13916764,0.001978095,0.030636055],"study_design_scores_gemma":[0.0076979357,0.0029456886,0.8481986,0.000033886376,0.00091630884,0.000006548794,0.0011980932,0.021084053,0.043986164,0.067535,0.006077619,0.00032010255],"about_ca_topic_score_codex":0.000007996011,"about_ca_topic_score_gemma":0.00000766335,"teacher_disagreement_score":0.78536874,"about_ca_system_score_codex":0.0000057910784,"about_ca_system_score_gemma":0.00003116288,"threshold_uncertainty_score":0.99867374},"labels":[],"label_agreement":null},{"id":"W4283719800","doi":"10.1016/j.bbi.2022.06.016","title":"Tetrahydrobiopterin modulates the behavioral neuroinflammatory response to an LPS challenge in mice","year":2022,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Bordeaux; Fondation pour la Recherche Médicale; Fondation FondaMental; Université Laval","keywords":"Tetrahydrobiopterin; Dopamine; Tyrosine hydroxylase; Dopaminergic; Monoamine neurotransmitter; Lipopolysaccharide; Endocrinology; Internal medicine; Chemistry; Pharmacology; Biology; Serotonin; Medicine; Nitric oxide synthase; Nitric oxide; Receptor","score_opus":0.04188160958849899,"score_gpt":0.2940762412087815,"score_spread":0.2521946316202825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283719800","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99708605,0.000057620728,9.4096276e-7,0.001789912,0.00017923403,0.0006293614,0.000057783604,0.00009013367,0.00010895195],"genre_scores_gemma":[0.99825215,0.000010787059,0.000017308224,0.0011394365,0.000012665898,0.00024571852,0.000005983359,0.00003165755,0.00028428092],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9971163,0.0015566979,0.00025878812,0.0004306209,0.00025439297,0.00038317064],"domain_scores_gemma":[0.99892753,0.00032958074,0.000055212407,0.00055033085,0.00001091567,0.00012644705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008028593,0.00020465386,0.00016928946,0.00020399498,0.00075777253,0.00008139113,0.00067699305,0.000047905298,0.0001652338],"category_scores_gemma":[0.00017516916,0.00018534386,0.000056812412,0.0004160771,0.0001861172,0.00021857859,0.0005417251,0.0005895228,0.000010400193],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049782236,0.0007994514,0.0017214798,0.0000039642114,5.774473e-7,0.00009862517,0.004968943,0.000037212714,0.9838075,0.000089166875,0.00007726038,0.007898011],"study_design_scores_gemma":[0.0014935526,0.0015649801,0.93939954,0.0000093537155,0.000011260855,0.00016379688,0.004868673,0.00013300173,0.04339449,0.000094282215,0.008318408,0.00054866594],"about_ca_topic_score_codex":0.00035799312,"about_ca_topic_score_gemma":0.0001754665,"teacher_disagreement_score":0.940413,"about_ca_system_score_codex":0.00005807591,"about_ca_system_score_gemma":0.000044289995,"threshold_uncertainty_score":0.7558103},"labels":[],"label_agreement":null},{"id":"W4283784589","doi":"10.1016/j.biopsych.2022.06.029","title":"Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation","year":2022,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"H. Lundbeck A/S; Norges Forskningsråd; Helse Sør-Øst RHF; Universitetet i Bergen; Sunovion","keywords":"Neuroinflammation; Cell adhesion molecule; Peripheral; Intracellular; Mental illness; Cell adhesion; Intercellular adhesion molecule; Adhesion; Intercellular Adhesion Molecule-1; Neuroscience; Medicine; Inflammation; Cell biology; Psychology; Immunology; Chemistry; Psychiatry; Biology; Internal medicine; Mental health","score_opus":0.010294531269782765,"score_gpt":0.21467665903272598,"score_spread":0.2043821277629432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283784589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980577,0.0008554025,0.000015057385,0.000121258025,0.00038197206,0.00025387257,0.0000138028,0.000024776213,0.0002761405],"genre_scores_gemma":[0.9995998,0.000086235705,0.0000822348,0.00015829768,0.000025571502,0.000017942753,0.000010815226,0.000007732955,0.000011376236],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987213,0.00033570852,0.0002861382,0.00034118738,0.00013842943,0.00017725091],"domain_scores_gemma":[0.9997431,0.000028497328,0.00009885746,0.00009670517,0.0000037149664,0.000029129094],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117755066,0.00011401978,0.00015409778,0.00010218524,0.00009068762,0.000013616203,0.00018470107,0.0000679222,0.00008210104],"category_scores_gemma":[0.000022102286,0.00009885283,0.000049864728,0.00019784708,0.000064630985,0.00005472088,0.00018301283,0.00021722898,0.0000019488089],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018141874,0.00018040165,0.049192738,0.00003660906,6.7285004e-7,0.000009721725,0.0005714584,0.0005323213,0.94728756,0.0004346829,0.000011046594,0.0015613443],"study_design_scores_gemma":[0.016446041,0.0047839796,0.5798131,0.00053547515,0.000021447946,0.0008700557,0.067156054,0.053423993,0.24699685,0.025603382,0.0015881937,0.0027614255],"about_ca_topic_score_codex":0.000025198298,"about_ca_topic_score_gemma":0.000012881783,"teacher_disagreement_score":0.70029074,"about_ca_system_score_codex":0.0000365878,"about_ca_system_score_gemma":0.000017937746,"threshold_uncertainty_score":0.40311018},"labels":[],"label_agreement":null},{"id":"W4284898628","doi":"10.47626/2237-6089-2022-0466","title":"Higher IL-6 and IL-4 plasma levels in depressed elderly women are influenced by diabetes mellitus","year":2022,"lang":"en","type":"article","venue":"Trends in Psychiatry and Psychotherapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; University of Texas Health Science Center at Houston","keywords":"Diabetes mellitus; Internal medicine; Medicine; Endocrinology","score_opus":0.017898676035104106,"score_gpt":0.27116889425343654,"score_spread":0.25327021821833245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4284898628","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918105,0.0030615188,0.0000032237172,0.002589212,0.0008852775,0.00016191941,0.00020954158,0.000065645916,0.0012131574],"genre_scores_gemma":[0.99350077,0.0010863706,0.00008708912,0.003981207,0.000044264467,0.00020303956,0.0000047590656,0.000038021833,0.0010544736],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9978568,0.00026669362,0.00033543387,0.00074100035,0.00024768474,0.0005524118],"domain_scores_gemma":[0.99931335,0.00013549399,0.00012498755,0.0002995571,0.000004489943,0.00012209026],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020153767,0.00028076628,0.00030733977,0.00038015906,0.00020485971,0.00007243437,0.00030973353,0.000096922806,0.0011506256],"category_scores_gemma":[0.0000041759304,0.00028082868,0.00004300657,0.0009323631,0.00015701143,0.00018281194,0.000018503368,0.00039920135,0.0000029498922],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023682034,0.003409874,0.3670119,0.00017186406,0.000083751154,0.00003197194,0.014194492,0.00026170502,0.12789248,0.0076725,0.02626625,0.45063502],"study_design_scores_gemma":[0.02127766,0.0019251878,0.71885437,0.00010467316,0.000007683877,0.000015713158,0.0015969799,0.0003086085,0.004718119,0.06827428,0.18127704,0.0016396978],"about_ca_topic_score_codex":0.000015390935,"about_ca_topic_score_gemma":0.00008107332,"teacher_disagreement_score":0.44899532,"about_ca_system_score_codex":0.000026300097,"about_ca_system_score_gemma":0.000018711158,"threshold_uncertainty_score":0.9999644},"labels":[],"label_agreement":null},{"id":"W4284990235","doi":"10.1016/j.bbr.2022.114000","title":"Differential effects of lipopolysaccharide on cognition, corticosterone and cytokines in socially-housed vs isolated male rats","year":2022,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Nucleus accumbens; Corticosterone; Sickness behavior; Psychology; Lipopolysaccharide; Social defeat; Internal medicine; Endocrinology; Cytokine; Environmental enrichment; Impulsivity; Social isolation; Neuroscience; Central nervous system; Developmental psychology; Medicine; Hormone; Psychiatry","score_opus":0.06787793602190126,"score_gpt":0.3348555929604777,"score_spread":0.26697765693857645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4284990235","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969255,0.00002699056,0.000006527173,0.0018077136,0.00016057125,0.00085985084,0.000058653437,0.000048752336,0.00010545825],"genre_scores_gemma":[0.9985804,0.000020284906,0.00000624256,0.0003906155,0.000024495585,0.00017741836,0.000013998931,0.000033313863,0.00075322675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99665594,0.0010690053,0.00030484336,0.000496103,0.0009215145,0.0005526154],"domain_scores_gemma":[0.9980823,0.0014505407,0.000080846505,0.0002163512,0.00005810468,0.000111858215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031420452,0.00016043447,0.00025719663,0.000449506,0.00041492903,0.00006523483,0.00033807335,0.00007062246,0.0005409071],"category_scores_gemma":[0.00094618107,0.00016009007,0.00005827102,0.0005987149,0.00035935198,0.000101980026,0.00039084684,0.00068371405,0.0000141593155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080669223,0.0006145718,0.0066790506,0.000051347553,0.0000040415584,0.00017764661,0.0005975542,0.000002373735,0.98770726,0.0005364867,0.0006632866,0.0021596672],"study_design_scores_gemma":[0.00381875,0.0019925307,0.13598385,0.00006843955,0.000009174536,0.00003147751,0.000391746,0.00024201997,0.8565269,0.0006124243,0.000051615003,0.00027106283],"about_ca_topic_score_codex":0.00023531784,"about_ca_topic_score_gemma":0.00013766908,"teacher_disagreement_score":0.13118039,"about_ca_system_score_codex":0.00007577252,"about_ca_system_score_gemma":0.0001007695,"threshold_uncertainty_score":0.6528284},"labels":[],"label_agreement":null},{"id":"W4285087788","doi":"10.1007/s00406-022-01460-2","title":"The effects of ketamine and classic hallucinogens on neurotrophic and inflammatory markers in unipolar treatment-resistant depression: a systematic review of clinical trials","year":2022,"lang":"en","type":"review","venue":"European Archives of Psychiatry and Clinical Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Hallucinogen; Ketamine; Antidepressant; Treatment-resistant depression; Context (archaeology); Depression (economics); Medicine; Clinical trial; Psychology; Brain-derived neurotrophic factor; Pharmacology; Neurotrophic factors; Psychiatry; Internal medicine; Anxiety","score_opus":0.10265034393293596,"score_gpt":0.40018742163155185,"score_spread":0.2975370776986159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285087788","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009808047,0.98547924,0.000002523782,0.0001005209,0.0010272397,0.0029183677,0.000059617083,0.000017079483,0.00058736734],"genre_scores_gemma":[0.00284881,0.99650383,0.000033841,0.00039777337,0.000053363943,0.00004120179,0.0000015076055,0.000044202905,0.000075470554],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9657847,0.02699572,0.0051137283,0.0012689099,0.00049656694,0.00034031572],"domain_scores_gemma":[0.9562386,0.03899288,0.0035335724,0.0009710801,0.00001010823,0.00025371386],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006354873,0.00051042653,0.0039051906,0.00022585814,0.00022986633,0.00003628452,0.00093640585,0.00008068759,0.000003431266],"category_scores_gemma":[0.036976185,0.00029451944,0.0009426638,0.00048205175,0.0026775543,0.000068331356,0.0005257379,0.00078746094,7.655539e-7],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050716905,0.0009984743,0.0008061402,0.6952488,0.00006125668,0.000099958444,0.000037674483,3.1146746e-7,0.00023137103,0.0010154601,0.000023555705,0.30096987],"study_design_scores_gemma":[0.0059271785,0.013150698,0.048631866,0.87173104,0.0027650432,0.000157523,0.00007351284,0.00011957273,0.000029648416,0.00032450416,0.05600156,0.0010878693],"about_ca_topic_score_codex":0.00000165769,"about_ca_topic_score_gemma":0.000003881797,"teacher_disagreement_score":0.299882,"about_ca_system_score_codex":0.000005296208,"about_ca_system_score_gemma":0.00025944243,"threshold_uncertainty_score":0.9999507},"labels":[],"label_agreement":null},{"id":"W4285089994","doi":"10.3389/fphar.2022.969453","title":"Editorial: Streaming Inflammation: From Damage to Healing and Resilience","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Inflammation; Resilience (materials science); Medicine; Immunology; Physics","score_opus":0.009386894976143825,"score_gpt":0.2877965988754035,"score_spread":0.2784097038992597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285089994","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010875663,0.0003385732,0.00022348891,0.000450144,0.9866724,0.00056728604,0.00037384703,0.000103519036,0.00039509096],"genre_scores_gemma":[0.0010908865,0.00068794144,0.0010049485,0.00047073775,0.9960167,0.00020009856,0.000112971946,0.00006034192,0.00035538353],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964667,0.00058349135,0.00048386154,0.0011392523,0.00075838336,0.00056834036],"domain_scores_gemma":[0.9977896,0.0014837465,0.00022335984,0.00027346108,0.00004171005,0.00018810468],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040209622,0.00035391562,0.0005390886,0.00050389854,0.00026883127,0.0000845203,0.00082867354,0.0005035941,0.00035520992],"category_scores_gemma":[0.0017678823,0.00041960468,0.00005558806,0.0005552796,0.00019728397,0.00021922911,0.00057365693,0.0015013169,0.000013285399],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026508566,0.000033798024,0.00007277762,0.000033080712,0.000011174163,0.000060062874,0.00067020516,0.00036353146,0.020064618,0.0000071922714,0.97549796,0.0029204886],"study_design_scores_gemma":[0.0013291608,0.00010507332,0.00003274369,0.000025319845,0.000020855898,4.2162662e-7,0.00034182385,0.0002753438,0.006405526,0.000492503,0.9905892,0.00038202183],"about_ca_topic_score_codex":0.00018422416,"about_ca_topic_score_gemma":0.000038690756,"teacher_disagreement_score":0.015091222,"about_ca_system_score_codex":0.0003303654,"about_ca_system_score_gemma":0.00033278627,"threshold_uncertainty_score":0.9998256},"labels":[],"label_agreement":null},{"id":"W4285230569","doi":"10.2139/ssrn.4115468","title":"Sociodemographic and Clinical Factors Associated with Clinical Outcome in Neuroinflammatory Conditions: An Eight-Year Multicenter Retrospective Cohort Study","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"","keywords":"Medicine; Etiology; Retrospective cohort study; Medical record; Cohort; Logistic regression; Pediatrics; Cohort study; Internal medicine","score_opus":0.04319571176324455,"score_gpt":0.3415696586612275,"score_spread":0.29837394689798297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285230569","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985786,0.000049718125,0.00001064099,0.00015736712,0.00031868357,0.0007319927,0.000025002417,0.000064247426,0.00006375156],"genre_scores_gemma":[0.99915206,0.00028455196,0.0000027438437,0.000325136,0.000064752916,0.000024744326,0.000008269137,0.00004384441,0.000093872324],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9934987,0.0026915062,0.0009514958,0.0007272716,0.00069081894,0.0014402536],"domain_scores_gemma":[0.9983791,0.00065186113,0.00046966705,0.00026122382,0.00005243388,0.00018571604],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0049022203,0.0002530349,0.00052995293,0.00026265334,0.00070178474,0.00008386105,0.0004222006,0.00009632685,0.00008539187],"category_scores_gemma":[0.001180326,0.00021339847,0.0001917319,0.0005009253,0.0003676858,0.00034001734,0.00012976462,0.0052727936,0.0000033982426],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017392276,0.0017984244,0.99592054,8.1751745e-7,0.000115268675,0.00004755786,0.00023107658,0.000008433727,0.00004985211,0.0015722603,0.0000133034555,0.0000685642],"study_design_scores_gemma":[0.005043008,0.003014832,0.980906,0.0000046592213,0.000055503533,0.000036303136,0.0062251114,0.00012125241,0.00000454246,0.004324334,0.000014976551,0.0002494608],"about_ca_topic_score_codex":0.000022998542,"about_ca_topic_score_gemma":0.0015480414,"teacher_disagreement_score":0.015014502,"about_ca_system_score_codex":0.00061928947,"about_ca_system_score_gemma":0.00064919906,"threshold_uncertainty_score":0.9970221},"labels":[],"label_agreement":null},{"id":"W4285501124","doi":"10.1016/j.bbi.2022.07.006","title":"Neutrophil-lymphocyte ratios as inflammatory biomarkers in psychiatric patients","year":2022,"lang":"en","type":"review","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":103,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario HIV Treatment Network; University of Toronto; University Health Network","funders":"","keywords":"Schizophrenia (object-oriented programming); Etiology; Pathological; Biomarker; Major depressive disorder; Psychiatry; Inflammation; Bipolar disorder; Medicine; Population; Clinical psychology; Psychology; Internal medicine; Mood; Biology","score_opus":0.04123552040344631,"score_gpt":0.31014976969969704,"score_spread":0.26891424929625074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285501124","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10752486,0.8877821,2.1420439e-7,0.00002625325,0.0007965035,0.0022164492,0.00014154143,0.0001098114,0.001402295],"genre_scores_gemma":[0.0016694899,0.9968831,0.000009406465,0.00036748766,0.000032067834,0.0005954025,0.00015878519,0.00008617502,0.00019808416],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961938,0.0014024063,0.00079943496,0.0007189809,0.0004003194,0.0004850122],"domain_scores_gemma":[0.998145,0.0005897799,0.00039274798,0.0007082383,0.000014405595,0.00014985433],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035133015,0.0005698962,0.00093364407,0.00074893323,0.00049007614,0.00010924838,0.00076722447,0.0002829732,0.00050521916],"category_scores_gemma":[0.00053371786,0.00054649735,0.0003556338,0.0011622809,0.00022489183,0.00022837301,0.00047638942,0.00090554566,0.000064480446],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034486002,0.00059045287,0.00059764093,0.0013250642,0.000012874313,0.000049722024,0.00016137816,1.18933606e-7,0.000049305527,0.00009657077,0.0004992745,0.9965831],"study_design_scores_gemma":[0.0015239873,0.00020673148,0.008176874,0.00035505617,0.00012692854,0.00004966757,0.00008573888,7.2057156e-7,0.000015231304,0.00003913543,0.98870194,0.0007179972],"about_ca_topic_score_codex":0.00015500218,"about_ca_topic_score_gemma":0.000022388478,"teacher_disagreement_score":0.9958651,"about_ca_system_score_codex":0.00025341334,"about_ca_system_score_gemma":0.0004248255,"threshold_uncertainty_score":0.99969864},"labels":[],"label_agreement":null},{"id":"W4285591430","doi":"10.3389/fpsyt.2022.974388","title":"Editorial: Role of serotonergic system in pathology of major depressive disorders","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"","keywords":"Serotonergic; Psychiatry; Depression (economics); Medicine; Psychology; Serotonin; Internal medicine","score_opus":0.0032319898185916157,"score_gpt":0.22420107839035977,"score_spread":0.22096908857176817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285591430","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004507057,0.0033940424,0.000043128235,0.00003744205,0.9884954,0.0008410582,0.00055496,0.000057061676,0.0020698647],"genre_scores_gemma":[0.022374786,0.0007210027,0.0009443121,0.000031368345,0.9750001,0.00050499814,0.000120991084,0.00016733225,0.00013515519],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954935,0.0006786864,0.0011038431,0.0010267011,0.0011285619,0.00056874513],"domain_scores_gemma":[0.99779636,0.00036674296,0.0009503722,0.00076419284,0.00004801233,0.0000743116],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042995624,0.0004590867,0.0011538768,0.0010092538,0.00007248681,0.00001433239,0.0013539459,0.0010661349,0.000043436983],"category_scores_gemma":[0.00072450796,0.0005022795,0.00027770654,0.0010341794,0.00032089275,0.00012403095,0.00029705765,0.0015158345,0.000002634993],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048109874,0.00039634047,0.005170004,0.00078432285,0.000020179403,0.000009483554,0.00040341014,0.00020088222,0.0006326554,0.0005012138,0.99105704,0.000343363],"study_design_scores_gemma":[0.007647778,0.00049977656,0.00055351155,0.00069215125,0.00006489044,0.000003346509,0.008293625,0.00016017669,0.0011809813,0.012746047,0.96711737,0.001040369],"about_ca_topic_score_codex":0.0002578423,"about_ca_topic_score_gemma":0.0002375534,"teacher_disagreement_score":0.023939699,"about_ca_system_score_codex":0.00021197021,"about_ca_system_score_gemma":0.0006954332,"threshold_uncertainty_score":0.99974287},"labels":[],"label_agreement":null},{"id":"W4285802297","doi":"10.2174/1568026622666220718155616","title":"Indoleamine 2,3-dioxygenase (IDO)-activity in Severe Psychiatric Disorders:A Systemic Review","year":2022,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Kynurenine; Kynurenine pathway; Bipolar disorder; Schizophrenia (object-oriented programming); Indoleamine 2,3-dioxygenase; Depression (economics); Psychiatry; Medicine; Major depressive disorder; Psychosis; Internal medicine; Clinical psychology; Tryptophan; Cognition; Biology; Genetics","score_opus":0.06987022219642954,"score_gpt":0.35690398639098453,"score_spread":0.287033764194555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285802297","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00051086146,0.99333656,0.000004098714,0.00012943252,0.0012442394,0.0012681128,0.000066535664,0.00006534634,0.0033748134],"genre_scores_gemma":[0.00034346752,0.9980687,0.0000047933277,0.00014605463,0.00049066794,0.0004965901,0.000078726815,0.000058874375,0.0003121176],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9956748,0.00049584714,0.0011443138,0.0012264134,0.00081482145,0.00064380054],"domain_scores_gemma":[0.9979362,0.00041673626,0.0006057282,0.00084970385,0.00001192462,0.00017971797],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00059519813,0.00071742665,0.0020229765,0.00024779502,0.00009404821,0.000022830975,0.0012105963,0.00029324772,0.0009727501],"category_scores_gemma":[0.0013361992,0.0006540211,0.0004499343,0.0018894426,0.00013932308,0.000089083915,0.0003446605,0.0028978677,0.000027066213],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000742146,0.00031731618,0.000018665485,0.19711687,0.000004910852,0.000059766146,0.000026387195,6.850512e-7,0.000014821687,0.000014929873,0.001185189,0.80123305],"study_design_scores_gemma":[0.0006673352,0.000028212047,0.00001025335,0.0507729,0.000059106227,0.00021560394,0.00002937268,0.000006121982,0.00002762476,0.00007452231,0.94748765,0.00062130665],"about_ca_topic_score_codex":0.000011731368,"about_ca_topic_score_gemma":0.000010087164,"teacher_disagreement_score":0.9463025,"about_ca_system_score_codex":0.0006074192,"about_ca_system_score_gemma":0.0005905559,"threshold_uncertainty_score":0.9999405},"labels":[],"label_agreement":null},{"id":"W4286567190","doi":"10.1016/j.jad.2022.07.020","title":"The effect of adjunctive infliximab treatment on future cardiovascular disease risk in patients with bipolar disorder","year":2022,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"Stanley Medical Research Institute","keywords":"Infliximab; Medicine; Internal medicine; Bipolar disorder; Placebo; Adjunctive treatment; Disease; Pathology","score_opus":0.0030949076727652632,"score_gpt":0.19944150684075235,"score_spread":0.19634659916798708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286567190","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99472463,0.0034612343,0.000037004527,0.00014500583,0.00038291814,0.0010534434,0.000088300876,0.000010504222,0.0000969367],"genre_scores_gemma":[0.99916893,0.0006077025,0.0000033984634,0.000042952863,0.000040551495,0.00008664045,0.0000032735595,0.000035627043,0.000010940291],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9961937,0.0017870568,0.0003179001,0.00035116574,0.0010229341,0.00032725805],"domain_scores_gemma":[0.9978756,0.0010734003,0.00046977305,0.00040676052,0.000061467115,0.000113022776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052620587,0.00031030763,0.00048587826,0.000291262,0.0004566045,0.00002499679,0.00036084597,0.000035076482,0.000017919101],"category_scores_gemma":[0.0005975281,0.00017282458,0.00056413695,0.00081097864,0.0002162467,0.00017647908,0.000071674694,0.0005135216,0.0000014896825],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0153338965,0.0018401537,0.68046576,0.00002727482,0.0006913952,0.00003104989,0.0011273995,0.049025074,0.000075054515,0.00010703967,0.00009081062,0.25118512],"study_design_scores_gemma":[0.022052536,0.02240129,0.932662,0.000037030914,0.0002835424,0.0000030955882,0.0011869946,0.00014582695,0.0014297423,0.00026256288,0.019184211,0.00035114802],"about_ca_topic_score_codex":0.000108535656,"about_ca_topic_score_gemma":0.00010313503,"teacher_disagreement_score":0.25219628,"about_ca_system_score_codex":0.00030201575,"about_ca_system_score_gemma":0.00010685201,"threshold_uncertainty_score":0.70475817},"labels":[],"label_agreement":null},{"id":"W4286629379","doi":"10.3389/fpsyt.2022.943869","title":"A Cross-Sectional Study on Associations Between BDNF, CRP, IL-6 and Clinical Symptoms, Cognitive and Personal Performance in Patients With Paranoid Schizophrenia","year":2022,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Saint Petersburg State University","keywords":"Schizophrenia (object-oriented programming); Positive and Negative Syndrome Scale; Paranoid schizophrenia; Internal medicine; Neuropsychology; Cognition; Psychiatry; Clinical psychology; Psychology; Medicine; Biomarker; Psychosis","score_opus":0.01747997591944975,"score_gpt":0.2892790430451047,"score_spread":0.27179906712565494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286629379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970838,0.000057051162,0.0000140751545,0.0000907092,0.0015617014,0.0006337387,0.00037885338,0.000026864764,0.0001532427],"genre_scores_gemma":[0.99924564,0.000008620164,0.00015821359,0.00035160346,0.000075344935,0.00006292576,0.000029588935,0.000019514122,0.00004854857],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99789816,0.0003200108,0.00038560253,0.00063472363,0.00048097485,0.0002804997],"domain_scores_gemma":[0.99946195,0.00018788925,0.00014794247,0.000103018785,0.000020824014,0.00007836162],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003854306,0.00017551433,0.00026037305,0.00026309025,0.00043642925,0.000065158216,0.0001479556,0.000071766575,0.000019727993],"category_scores_gemma":[0.0001247938,0.00017279912,0.000038708033,0.00045359432,0.0002281346,0.00017940157,0.00009660411,0.00068405096,0.0000022552067],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010503016,0.0011081146,0.99558485,0.0000056426306,0.00002748588,0.0000015302214,0.00048506705,0.000008367543,3.488851e-7,0.000019928186,0.0002541175,0.0014542685],"study_design_scores_gemma":[0.009377494,0.0015304263,0.98785883,0.000015702311,0.000012024412,8.251089e-7,0.00069708953,0.00012220074,0.0000013427621,0.000149228,0.000027380047,0.00020748179],"about_ca_topic_score_codex":0.0000108277,"about_ca_topic_score_gemma":0.00003711719,"teacher_disagreement_score":0.008327193,"about_ca_system_score_codex":0.00008318788,"about_ca_system_score_gemma":0.000104504994,"threshold_uncertainty_score":0.70465434},"labels":[],"label_agreement":null},{"id":"W4289040432","doi":"10.17615/vamr-8z97","title":"Association of baseline inflammatory markers and the development of negative symptoms in individuals at clinical high risk for psychosis","year":2021,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Mental Health; National Institutes of Health","keywords":"Psychosis; Association (psychology); Medicine; Baseline (sea); Internal medicine; Psychology; Psychiatry; Biology; Psychotherapist","score_opus":0.020368530801943202,"score_gpt":0.2653993975046819,"score_spread":0.2450308667027387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289040432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978588,0.00009792902,0.00015476093,0.0011802153,0.00012893417,0.00027737409,0.00006939245,0.000012251553,0.00022034573],"genre_scores_gemma":[0.98930407,0.00008201742,0.00953754,0.0004994998,0.000024830068,0.000044414035,0.000010745486,0.000010976141,0.00048592838],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984463,0.0005046776,0.0005244004,0.00020709504,0.00019432843,0.00012322294],"domain_scores_gemma":[0.9932582,0.0061790263,0.0003780843,0.000119838696,0.0000384469,0.000026447098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009582788,0.00008226146,0.00023204894,0.00005018652,0.00008485618,0.000025538979,0.00011443306,0.000078931356,0.000045101253],"category_scores_gemma":[0.0060760123,0.000060459508,0.000058120404,0.0002114855,0.0002873279,0.00017155815,0.00011473343,0.00008908396,0.0000011065764],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007099716,0.00016296137,0.93616945,0.00008962087,0.000118048076,4.2327338e-7,0.006476584,0.000011680214,0.0010668726,0.040551376,0.0034233355,0.0112196645],"study_design_scores_gemma":[0.0066147037,0.00005153734,0.734494,0.00006293636,0.000027791226,2.2896552e-7,0.00079854834,0.00014408713,0.20802638,0.046739906,0.002903315,0.0001366056],"about_ca_topic_score_codex":0.0000053425933,"about_ca_topic_score_gemma":0.00009468896,"teacher_disagreement_score":0.2069595,"about_ca_system_score_codex":0.000018248518,"about_ca_system_score_gemma":0.00013814204,"threshold_uncertainty_score":0.72739935},"labels":[],"label_agreement":null},{"id":"W4289223936","doi":"10.1113/ep090381","title":"Kynurenine metabolism is altered in <i>mdx</i> mice: a potential muscle to brain connection","year":2022,"lang":"en","type":"article","venue":"Experimental Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St Joseph's Health Care; Brock University","funders":"","keywords":"Kynurenine; Kynurenic acid; Kynurenine pathway; Duchenne muscular dystrophy; Endocrinology; Internal medicine; mdx mouse; Muscular dystrophy; Neuroprotection; Anxiety; Biology; Dystrophin; Medicine; Glutamate receptor; Receptor; Biochemistry; Psychiatry; Tryptophan","score_opus":0.015912400186022392,"score_gpt":0.27662373132455875,"score_spread":0.26071133113853634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289223936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958006,0.00016890137,0.000014264425,0.0018444227,0.0011846595,0.00033099472,0.00004122051,0.000068946974,0.0005459812],"genre_scores_gemma":[0.9793526,0.0000027654482,0.000051412324,0.019870417,0.00015859936,0.00021440147,0.000015436019,0.000022750022,0.0003116047],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983761,0.00029022055,0.00020296709,0.00058962364,0.00018122248,0.00035987195],"domain_scores_gemma":[0.9996005,0.000054926946,0.00005769508,0.00020447702,0.0000054327243,0.000076952434],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006592593,0.0001614505,0.00021255818,0.0001506827,0.00021698284,0.00001586964,0.0002935434,0.000038293045,0.002203004],"category_scores_gemma":[0.000038762013,0.0001763006,0.000085343796,0.00040094097,0.00007852882,0.000100666475,0.00033732108,0.00019534513,0.000107120184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002825261,0.0003552966,8.0475587e-7,0.0000015873279,0.0000029077182,0.000008352955,0.0019878547,0.00029460446,0.9842656,0.0005926527,0.011903663,0.0003041207],"study_design_scores_gemma":[0.0016330262,0.00039777317,0.0049382923,0.0000015835307,0.0000013427286,0.000018084755,0.0015705453,0.00023353087,0.966049,0.000570217,0.024364704,0.00022186205],"about_ca_topic_score_codex":0.00013237017,"about_ca_topic_score_gemma":0.0000063640905,"teacher_disagreement_score":0.018216591,"about_ca_system_score_codex":0.00006882202,"about_ca_system_score_gemma":0.000021782487,"threshold_uncertainty_score":0.99870914},"labels":[],"label_agreement":null},{"id":"W4289305615","doi":"","title":"Exploring the effects of tetrahydrobiopterin on motivation, dopamine release and acute inflammation in mice","year":2021,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Tetrahydrobiopterin; Dopamine; Inflammation; Neuroscience; Chemistry; Pharmacology; Medicine; Psychology; Endocrinology; Internal medicine; Nitric oxide; Nitric oxide synthase","score_opus":0.024299457074093922,"score_gpt":0.22254608314907268,"score_spread":0.19824662607497875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289305615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916014,0.00016112607,0.0016910246,0.0031356236,0.0001852234,0.0004983514,0.000010976158,0.00006198244,0.0026542826],"genre_scores_gemma":[0.9972375,0.0012122917,0.00089524,0.00008435925,0.000010823242,0.00010581436,0.000051429804,0.000023597762,0.00037891994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956327,0.0029042102,0.00039984853,0.0005790068,0.00028578754,0.0001984391],"domain_scores_gemma":[0.9947375,0.0036609576,0.0003289645,0.0009240667,0.0002868665,0.00006165626],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011282114,0.00022228138,0.0002469273,0.00020447782,0.00014477508,0.00017704169,0.0005669108,0.000096795746,0.000009221691],"category_scores_gemma":[0.0062186965,0.00020049853,0.0000797504,0.0004628982,0.00020799713,0.00020578991,0.00062943465,0.0004619851,0.0000030444523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000317336,0.00039162443,0.00065248244,0.00061266933,0.000025594452,0.00001894814,0.013272042,0.00017180588,0.91931176,0.013533203,0.000023695513,0.05195443],"study_design_scores_gemma":[0.0004940393,8.749676e-7,0.02201478,0.0019391751,0.000012163817,0.000004455524,0.00012355787,0.0019527822,0.97263485,0.00047838083,0.00016133806,0.00018358648],"about_ca_topic_score_codex":0.0002215582,"about_ca_topic_score_gemma":0.00028566676,"teacher_disagreement_score":0.053323098,"about_ca_system_score_codex":0.000053149568,"about_ca_system_score_gemma":0.00007634692,"threshold_uncertainty_score":0.81760925},"labels":[],"label_agreement":null},{"id":"W4291008771","doi":"10.1192/j.eurpsy.2022.2300","title":"Associations between childhood maltreatment and oxidative nucleoside damage in affective disorders","year":2022,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"Cilag; Fonden til Lægevidenskabens Fremme; Bausch Health; H. Lundbeck A/S; Beckett-Fonden; Gangstedfonden; Canadian Institutes of Health Research; A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal; Sunovion; Danmarks Frie Forskningsfond; Region Hovedstaden; Gentofte Hospital; Lundbeckfonden; Helsefonden; Eisai; Purdue University; Sundhed og Sygdom, Det Frie Forskningsråd; Novo Nordisk; Sanofi; Pfizer","keywords":"Psychology; Nucleoside; Clinical psychology; Medicine; Psychiatry; Chemistry; Biochemistry","score_opus":0.011470393055160852,"score_gpt":0.24130233693252012,"score_spread":0.22983194387735928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291008771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95572615,0.00014606377,0.00001569852,0.0019933928,0.0002877504,0.00039892868,0.00027041888,0.00010310402,0.04105851],"genre_scores_gemma":[0.9983427,0.000022668277,0.00018160275,0.0010631991,0.00006888005,0.000018775761,0.000028127148,0.00004520484,0.00022883111],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99783134,0.0009351793,0.00021050511,0.0005103597,0.00022338243,0.00028923893],"domain_scores_gemma":[0.9993845,0.00019352812,0.00012368444,0.0002164309,0.000004243773,0.00007760738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024997134,0.0001752611,0.00016649727,0.00016574448,0.00047850062,0.00004504853,0.00024926852,0.000016867532,0.00013927704],"category_scores_gemma":[0.00012128295,0.00018590661,0.00006424744,0.0004792039,0.000076980374,0.00013106881,0.0002543798,0.0003392917,0.000059649374],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047411857,0.0022056275,0.9418899,0.000013222847,0.00006934494,0.000038819104,0.017421147,0.00019463962,0.0027151438,0.012467041,0.005213339,0.017724372],"study_design_scores_gemma":[0.001324481,0.00022857652,0.9918599,0.0000107552105,0.000010070943,0.000002214429,0.0018488584,0.000008740801,0.00016509077,0.0030209767,0.0013039897,0.00021633507],"about_ca_topic_score_codex":0.00003939824,"about_ca_topic_score_gemma":0.00017136786,"teacher_disagreement_score":0.04997002,"about_ca_system_score_codex":0.00007977144,"about_ca_system_score_gemma":0.000040252562,"threshold_uncertainty_score":0.75810516},"labels":[],"label_agreement":null},{"id":"W4291701539","doi":"10.21203/rs.3.rs-1940296/v1","title":"Microbiome Mediates Development of PTSD and Resilience","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; European Commission","keywords":"Resilience (materials science); Microbiome; Psychology; Biology; Materials science; Bioinformatics","score_opus":0.08183440810268348,"score_gpt":0.38640965015372,"score_spread":0.3045752420510365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291701539","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949149,0.0011629817,0.000020874895,0.00041894734,0.0001624775,0.0007202852,0.00012404278,0.000052215073,0.0024233104],"genre_scores_gemma":[0.9973873,0.00062783126,0.0007914739,0.000041919113,0.000028130044,0.00016217506,0.000024882886,0.000027124877,0.0009091695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99657965,0.00055201113,0.00033739425,0.0008204875,0.0011682132,0.00054221816],"domain_scores_gemma":[0.99834657,0.00079035957,0.00010371469,0.00050923415,0.000104788756,0.00014531854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011832669,0.00018436952,0.00026103787,0.00055946416,0.00038229287,0.000079763755,0.0008906444,0.00013006489,0.00064691814],"category_scores_gemma":[0.0014367923,0.00017494551,0.00005888947,0.0006368308,0.00062266504,0.000055195153,0.0037761622,0.0010405736,0.00003143978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013395207,0.00039853764,0.001661124,0.0030518507,0.000017756076,0.00009870629,0.013157515,0.00008063172,0.9581125,0.0014308839,0.0029135817,0.018943],"study_design_scores_gemma":[0.00067428476,0.0002110039,0.023846142,0.00053112727,0.0000032320265,0.000013187898,0.005267559,0.000119068034,0.9295748,0.0034963973,0.035692338,0.0005708713],"about_ca_topic_score_codex":0.000049338916,"about_ca_topic_score_gemma":0.000029733885,"teacher_disagreement_score":0.032778755,"about_ca_system_score_codex":0.00012166302,"about_ca_system_score_gemma":0.00074172794,"threshold_uncertainty_score":0.7134071},"labels":[],"label_agreement":null},{"id":"W4292466623","doi":"10.3390/biomedicines10081929","title":"The Relationship between Stress, Inflammation, and Depression","year":2022,"lang":"en","type":"review","venue":"Biomedicines","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Hanyang University","keywords":"Inflammation; Depression (economics); Chronic stress; Medicine; Psychoneuroimmunology; Narrative review; Bioinformatics; Immunology; Immune system; Internal medicine; Intensive care medicine; Biology","score_opus":0.1233485117920788,"score_gpt":0.3538987368089089,"score_spread":0.2305502250168301,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292466623","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016711079,0.99818283,0.0000053299204,0.000238466,0.00038929872,0.00041271473,0.000043615415,0.00006306155,0.00049756357],"genre_scores_gemma":[0.00048219349,0.99827373,0.0000047692156,0.000022712531,0.00051640073,0.0000879661,0.0000679664,0.000022136483,0.000522117],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986722,0.00027529363,0.00033862388,0.00030762862,0.00024450183,0.00016177839],"domain_scores_gemma":[0.99402624,0.0053861146,0.00023872143,0.00028105828,0.000007812924,0.00006002063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021444767,0.0001837101,0.00035233042,0.00014809982,0.0006546501,0.000053482385,0.00032028666,0.00009760131,0.000043227825],"category_scores_gemma":[0.003454747,0.00010038566,0.00007149286,0.0005327906,0.0002634972,0.000059957434,0.00015472315,0.00025531414,0.000019179795],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[9.4595873e-7,0.0000031973188,0.0010028117,0.0013032291,0.000004375624,0.0000027327783,0.00004687865,1.1481129e-8,0.000002256088,0.0004965687,0.001833239,0.99530375],"study_design_scores_gemma":[0.00009263663,0.000012845559,0.0012959319,0.0010722834,0.000054302676,0.0000075942667,0.000047674726,3.8861376e-7,0.000008326131,0.00062105455,0.99667424,0.00011271568],"about_ca_topic_score_codex":0.000004857171,"about_ca_topic_score_gemma":0.000003122703,"teacher_disagreement_score":0.99519104,"about_ca_system_score_codex":0.000021601682,"about_ca_system_score_gemma":0.00007065368,"threshold_uncertainty_score":0.50351053},"labels":[],"label_agreement":null},{"id":"W4293113294","doi":"10.3389/fnagi.2022.821866","title":"Perspectives on the complex links between depression and dementia","year":2022,"lang":"en","type":"review","venue":"Frontiers in Aging Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"University of Ottawa","keywords":"Dementia; Depression (economics); Psychology; Psychiatry; Neuroscience; Cognitive psychology; Medicine; Disease; Internal medicine","score_opus":0.09458242239838202,"score_gpt":0.325465082047616,"score_spread":0.23088265964923396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293113294","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00032538173,0.9947092,0.00046737978,0.00035516013,0.0013506919,0.0009849432,0.000052574964,0.00011160467,0.0016430856],"genre_scores_gemma":[0.0043058563,0.9941462,0.00016870185,0.0010349649,0.00006357105,0.0000968979,0.0000033381032,0.000046018547,0.0001344013],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962107,0.0008546574,0.0003792907,0.0014099785,0.0006098622,0.00053549354],"domain_scores_gemma":[0.99819714,0.00084515876,0.00027540387,0.00057786994,0.000005417109,0.00009901534],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048729728,0.0004086745,0.00070774794,0.00045777072,0.0008048692,0.00022759978,0.0015041822,0.00012646249,0.000051721992],"category_scores_gemma":[0.0011239073,0.00028663612,0.00016737763,0.0012953309,0.0007640253,0.00015489462,0.000645974,0.001543375,0.0000050730096],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000049427586,0.000097672266,0.0008612163,0.0006651255,0.0000064456844,0.00005578686,0.00096639816,0.000011321333,0.000107347725,0.0006328955,0.005574695,0.99101615],"study_design_scores_gemma":[0.00012629446,0.000048751794,0.00069635466,0.0006392086,0.000037648344,0.000014819022,0.00041511972,0.0001603913,0.000027994194,0.000216939,0.9972727,0.0003437826],"about_ca_topic_score_codex":0.000005298418,"about_ca_topic_score_gemma":4.903745e-7,"teacher_disagreement_score":0.991698,"about_ca_system_score_codex":0.000099191144,"about_ca_system_score_gemma":0.00009726671,"threshold_uncertainty_score":0.9999586},"labels":[],"label_agreement":null},{"id":"W4293152225","doi":"10.1007/7854_2022_385","title":"Evolutionary Aspects of Diverse Microbial Exposures and Mental Health: Focus on “Old Friends” and Stress Resilience","year":2022,"lang":"en","type":"article","venue":"Current topics in behavioral neurosciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Military and Veteran Health Research","funders":"National Center for Complementary and Integrative Health; National Heart, Lung, and Blood Institute","keywords":"Stressor; Disease; Psychosocial; Hygiene hypothesis; Psychological resilience; Inflammation; Mental health; Mood; Medicine; Immunology; Mood disorders; Anxiety; Preparedness; Psychiatry; Allergy; Psychology; Social psychology; Pathology","score_opus":0.0559324010372536,"score_gpt":0.3265545642144334,"score_spread":0.2706221631771798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293152225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99641126,0.00049734395,0.0000012560193,0.0006982727,0.0017632656,0.0002716842,0.00024078328,0.000019905503,0.00009624718],"genre_scores_gemma":[0.9994219,0.0003124742,0.000019312563,0.0001344725,0.000023106957,0.000015961516,0.0000026939285,0.0000048562542,0.00006523562],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982238,0.00019903897,0.00024652638,0.0005873968,0.000447361,0.00029589992],"domain_scores_gemma":[0.9995684,0.00005391874,0.00012459146,0.00015362813,0.000007773802,0.00009170273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011887616,0.00013776238,0.0001609777,0.0001937002,0.0005030792,0.00003852031,0.00034275002,0.00001926519,0.00002781643],"category_scores_gemma":[0.000053052998,0.00013361647,0.0000303512,0.00040924942,0.0006679413,0.00017937164,0.0004047057,0.00025153242,5.210469e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002464158,0.0042602234,0.63291574,0.00013089189,0.0000011147185,0.00008761549,0.006022224,0.00023083464,0.22505847,0.042178907,0.0017512504,0.08711629],"study_design_scores_gemma":[0.0032957564,0.005997807,0.8772893,0.000185582,0.000009971258,0.0001211465,0.0050577894,0.00073361705,0.09372432,0.0049113384,0.007662897,0.0010104643],"about_ca_topic_score_codex":0.00006730964,"about_ca_topic_score_gemma":0.000051871186,"teacher_disagreement_score":0.24437355,"about_ca_system_score_codex":0.000046678142,"about_ca_system_score_gemma":0.00005955423,"threshold_uncertainty_score":0.54487216},"labels":[],"label_agreement":null},{"id":"W4293217574","doi":"10.3390/ijms23179653","title":"Effects of Two Distinct Psychoactive Microbes, Lacticaseibacillus rhamnosus JB-1 and Limosilactobacillus reuteri 6475, on Circulating and Hippocampal mRNA in Male Mice","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre; University of Alberta; St. Joseph’s Healthcare Hamilton; McMaster University; St. Joseph's Hospital","funders":"","keywords":"Hippocampal formation; Biology; Hippocampus; Lactobacillus reuteri; Neuroscience; Genetics; Probiotic; Bacteria","score_opus":0.015713691230835145,"score_gpt":0.2869247058067158,"score_spread":0.27121101457588065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293217574","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973168,0.00044282834,0.0002073664,0.0007394534,0.00049883744,0.00011414964,0.000012614757,0.000004462449,0.0006635018],"genre_scores_gemma":[0.99884045,0.00005455365,0.00048283578,0.00057003245,0.000028536251,0.0000037400391,3.6810408e-7,0.000006983208,0.000012473681],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981329,0.00026503645,0.0003392102,0.00029764336,0.0007854138,0.000179809],"domain_scores_gemma":[0.9988343,0.000571236,0.00039277645,0.0000658873,0.00006244615,0.00007333122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004648287,0.00012892832,0.00018498846,0.00034843493,0.00013509547,0.00008931226,0.00048235033,0.000021434664,0.000026261754],"category_scores_gemma":[0.0005652737,0.000113393646,0.000066310844,0.0003138485,0.00035921112,0.00022399513,0.00018110654,0.00026162874,6.990567e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022755122,0.00022121776,0.0032237535,0.000015535756,0.000019903275,0.0010063946,0.0007851997,0.0006358763,0.9847122,0.0012302147,0.00001612107,0.007906026],"study_design_scores_gemma":[0.0070378524,0.0024226953,0.050411344,0.0003600624,0.000036504633,0.007328256,0.0018313752,0.0024595554,0.91965896,0.0073725623,0.0004981224,0.0005827366],"about_ca_topic_score_codex":0.000039918457,"about_ca_topic_score_gemma":0.0000072831194,"teacher_disagreement_score":0.06505327,"about_ca_system_score_codex":0.000076756056,"about_ca_system_score_gemma":0.00008099226,"threshold_uncertainty_score":0.46240586},"labels":[],"label_agreement":null},{"id":"W4293242509","doi":"10.1016/j.biopsych.2022.02.598","title":"P362. Perturbed Inflammatory Networks in People With Depressive Symptoms","year":2022,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Hospital; University of Toronto","funders":"","keywords":"Depression (economics); Inflammation; Proinflammatory cytokine; Pathophysiology; Depressive symptoms; Medicine; Inflammatory response; Immunology; Psychology; Psychiatry; Internal medicine; Anxiety","score_opus":0.013313071394175171,"score_gpt":0.22589989434309035,"score_spread":0.21258682294891518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293242509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99524224,0.0005040299,0.000112184105,0.0007394454,0.00065377634,0.000315187,0.000010319751,0.00014491874,0.0022779044],"genre_scores_gemma":[0.9953694,0.000030023524,0.00007117276,0.004136868,0.00011135915,0.00015077752,0.000007756702,0.000014920024,0.00010776163],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99835676,0.00029461534,0.00020768333,0.0005468144,0.00019455813,0.00039958916],"domain_scores_gemma":[0.99939114,0.00017766247,0.00009154206,0.00024772232,0.0000070577335,0.000084871295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010524263,0.0001774087,0.00019001779,0.00007623922,0.00025196694,0.000023963748,0.00043885343,0.00008945627,0.0004898115],"category_scores_gemma":[0.000081235536,0.00012327844,0.00006903166,0.00049192796,0.00013850575,0.000058218342,0.0002076143,0.00045952157,0.000017222514],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063763995,0.000552137,0.9751125,0.000010356882,0.00000945982,0.000051094783,0.00020672179,0.004868343,0.003708194,0.010219016,0.003163951,0.0014606103],"study_design_scores_gemma":[0.0027533066,0.000993279,0.9817955,0.000019555822,0.0000050013323,0.00008474119,0.00060289225,0.0020464151,0.00021349406,0.0022587194,0.008608391,0.0006186921],"about_ca_topic_score_codex":0.000009809608,"about_ca_topic_score_gemma":0.000058794267,"teacher_disagreement_score":0.007960296,"about_ca_system_score_codex":0.000040912724,"about_ca_system_score_gemma":0.00006518573,"threshold_uncertainty_score":0.53630924},"labels":[],"label_agreement":null},{"id":"W4293585417","doi":"10.1016/j.bbih.2022.100499","title":"Immune characterization of suicidal behavior in female adolescents","year":2022,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Center for Advancing Translational Sciences; Janssen Research and Development; Jordan Elizabeth Harris Foundation; ACADIA Pharmaceuticals; Hersh Foundation","keywords":"Mass cytometry; Immune system; Cluster of differentiation; Immunology; Peripheral blood mononuclear cell; CXCR3; Immune dysregulation; Flow cytometry; Medicine; Chemokine; Chemokine receptor; Biology; Cell; Phenotype; Genetics","score_opus":0.045839051133279414,"score_gpt":0.3167545171294994,"score_spread":0.27091546599622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293585417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971483,0.00006680826,0.000012661479,0.0006368123,0.00040929104,0.0013322356,0.00025289707,0.00009112938,0.00004989849],"genre_scores_gemma":[0.9975053,0.000036340993,0.000024755314,0.0015757894,0.000015935406,0.00035292353,0.00017368447,0.000047041733,0.0002682485],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99642074,0.0012087714,0.0007909377,0.00042008175,0.00055670436,0.00060274906],"domain_scores_gemma":[0.9986626,0.00009362514,0.0004419717,0.0006417608,0.00002950373,0.00013052727],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007901543,0.00023156872,0.0004160137,0.00040929182,0.0005497853,0.000027587286,0.0007001541,0.00006909489,0.0004353808],"category_scores_gemma":[0.00016420841,0.00027938536,0.00012964397,0.0010057578,0.00016016282,0.00021846987,0.00039652956,0.0007524045,0.000015020714],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011810679,0.0028513777,0.08168782,0.00007660711,8.680698e-7,0.000025275414,0.001681077,0.0000058942665,0.903264,0.00012715082,0.000021359985,0.010140494],"study_design_scores_gemma":[0.0013567898,0.0004377802,0.95182985,0.000030908035,0.0000053499966,0.000027872982,0.00085448683,0.00001847228,0.044821966,0.000007002627,0.00037741195,0.00023212707],"about_ca_topic_score_codex":0.0019358632,"about_ca_topic_score_gemma":0.0001167412,"teacher_disagreement_score":0.870142,"about_ca_system_score_codex":0.00029311268,"about_ca_system_score_gemma":0.00033226068,"threshold_uncertainty_score":0.99996585},"labels":[],"label_agreement":null},{"id":"W4294000603","doi":"10.1016/j.jprot.2022.104713","title":"Plasma proteomic signature of major depressive episode in the elderly","year":2022,"lang":"en","type":"article","venue":"Journal of Proteomics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institutes of Health; Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Depression (economics); Disease; Population; Psychological intervention; Medicine; Clinical significance; Major depressive disorder; Late life depression; Bioinformatics; Gerontology; Psychology; Internal medicine; Biology; Psychiatry; Environmental health; Cognition","score_opus":0.015813370868785828,"score_gpt":0.24781820560102377,"score_spread":0.23200483473223793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294000603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965252,0.000091622554,0.00030147328,0.0018672545,0.00018796409,0.0007225851,0.000019274452,0.000005268825,0.00027930553],"genre_scores_gemma":[0.9977635,0.00001646807,0.0015811713,0.00044280005,0.000064560634,0.000051644725,3.3717515e-7,0.000014702863,0.00006477978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99821484,0.0004203853,0.00047212228,0.00015113343,0.0005332245,0.00020831692],"domain_scores_gemma":[0.99884033,0.00021178163,0.0006782737,0.0001903607,0.000041569274,0.000037688886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058533525,0.00011607838,0.00022331324,0.00018908617,0.00014254625,0.000029298899,0.00089987647,0.000054184944,0.00007757135],"category_scores_gemma":[0.0005410108,0.00008085599,0.00013788648,0.00039997266,0.000089305766,0.0001591635,0.000105640414,0.00097388134,0.0000019785873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046902313,0.0002828909,0.000533053,0.000030125999,0.000008865096,0.00014950059,0.0016207335,0.0022795605,0.99112076,0.0009355826,0.0009585661,0.0016113208],"study_design_scores_gemma":[0.00313318,0.0013906108,0.00209115,0.0000456747,0.000014616993,0.0006808048,0.001231322,0.0004951591,0.98106164,0.008705604,0.0009682108,0.00018201159],"about_ca_topic_score_codex":0.000010266301,"about_ca_topic_score_gemma":0.0000064994515,"teacher_disagreement_score":0.010059122,"about_ca_system_score_codex":0.00005883342,"about_ca_system_score_gemma":0.00014405041,"threshold_uncertainty_score":0.4231084},"labels":[],"label_agreement":null},{"id":"W4294281202","doi":"10.1038/s41380-022-01725-1","title":"Integrative multi-omics landscape of fluoxetine action across 27 brain regions reveals global increase in energy metabolism and region-specific chromatin remodelling","year":2022,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Agency for Science, Technology and Research; Hope for Depression Research Foundation","keywords":"Neuroscience; Hippocampal formation; Biology; Chromatin; Nucleus accumbens; Dorsal raphe nucleus; Dentate gyrus; Serotonergic; Genetics; Gene; Dopamine; Receptor; Serotonin","score_opus":0.021990489970173135,"score_gpt":0.27754604121201126,"score_spread":0.25555555124183815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294281202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9684892,0.0029887103,0.02484262,0.002388456,0.0005624259,0.00025537758,0.00010134167,0.00006021502,0.00031160717],"genre_scores_gemma":[0.9944306,0.0004265579,0.00319741,0.0016972353,0.000040813564,0.000038549046,0.000024328836,0.000030382856,0.000114126145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99777937,0.0005619563,0.00041903928,0.00061020866,0.00029185042,0.00033756834],"domain_scores_gemma":[0.99913776,0.000090161804,0.00024921136,0.00039391458,0.00002888675,0.00010009554],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026280165,0.00023729591,0.00031932103,0.00013839496,0.00023131284,0.00003895281,0.0003040075,0.00007433865,0.000017415698],"category_scores_gemma":[0.00015740478,0.00024299095,0.00012385451,0.00091029075,0.00014442616,0.00011457126,0.00019600427,0.0002858286,0.0000014791171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011407176,0.0016398508,0.0043550627,0.00013535965,0.000051915606,0.00022857757,0.0032533933,0.008971751,0.80395234,0.1571683,0.011411163,0.007691592],"study_design_scores_gemma":[0.05110006,0.0018584119,0.06114992,0.0010420819,0.00018893997,0.0034686269,0.060230013,0.14514884,0.3452669,0.24294394,0.08062626,0.0069759907],"about_ca_topic_score_codex":0.00017136814,"about_ca_topic_score_gemma":0.00019631413,"teacher_disagreement_score":0.4586854,"about_ca_system_score_codex":0.000059266873,"about_ca_system_score_gemma":0.000077878656,"threshold_uncertainty_score":0.9908883},"labels":[],"label_agreement":null},{"id":"W4294627626","doi":"10.1017/s000711452200232x","title":"Effects of inulin supplementation on inflammatory biomarkers and clinical symptoms of women with obesity and depression on a calorie-restricted diet: a randomised controlled clinical trial","year":2022,"lang":"en","type":"article","venue":"British Journal Of Nutrition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Medicine; Internal medicine; Gut flora; Depression (economics); Prebiotic; Obesity; Major depressive disorder; Endocrinology; Physiology; Immunology; Biology","score_opus":0.014367963406827574,"score_gpt":0.28796234833917933,"score_spread":0.2735943849323518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294627626","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99761915,0.00023622137,0.000029194813,0.00005020212,0.00029017156,0.0017169949,0.00003332405,0.000008677273,0.000016049991],"genre_scores_gemma":[0.99864197,0.0009472223,0.000059611495,0.00012501972,0.000118303135,0.000089086745,0.000004316889,0.000011921695,0.0000025765808],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99615127,0.0017049434,0.0011727561,0.0002472614,0.00055258424,0.00017117723],"domain_scores_gemma":[0.99501616,0.0035728582,0.0010948271,0.00007531999,0.00008921061,0.00015161182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014568458,0.000118496864,0.00067468645,0.00018780048,0.00013423219,0.000032896245,0.000120273835,0.000079244666,0.00002231914],"category_scores_gemma":[0.0030666308,0.0001101233,0.00015483022,0.0001986533,0.00022864692,0.00013400988,0.00003708257,0.0003606179,1.21339e-7],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9536806,0.0057387813,0.005204868,0.00017437433,0.0001394496,0.0002623301,0.00013810433,0.000007460108,0.011242044,0.000016081973,0.00046500366,0.022930909],"study_design_scores_gemma":[0.7962795,0.024977755,0.17215487,0.0005703865,0.000094473675,0.00009997718,0.00028968573,0.00008338243,0.00509188,0.00016125418,0.00006111195,0.00013572555],"about_ca_topic_score_codex":0.000012001637,"about_ca_topic_score_gemma":0.0000040908208,"teacher_disagreement_score":0.16695,"about_ca_system_score_codex":0.000060909064,"about_ca_system_score_gemma":0.00008317887,"threshold_uncertainty_score":0.44906977},"labels":[],"label_agreement":null},{"id":"W4294883938","doi":"10.1523/jneurosci.2410-21.2022","title":"Alterations in Astrocytic Regulation of Excitation and Inhibition by Stress Exposure and in Severe Psychopathology","year":2022,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"National Health and Medical Research Council; Medical Research Council; Rebecca L. Cooper Medical Research Foundation; National Alliance for Research on Schizophrenia and Depression","keywords":"Psychopathology; Context (archaeology); Neuroscience; Schizophrenia (object-oriented programming); Inhibitory postsynaptic potential; Psychology; Chronic stress; Excitatory postsynaptic potential; Astrocyte; Psychiatry; Medicine; Biology; Central nervous system","score_opus":0.018866901342577444,"score_gpt":0.2636804222305477,"score_spread":0.24481352088797026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294883938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99904627,0.000056279703,0.00020005852,0.0004392749,0.00013876872,0.000077304656,0.000011350938,0.000002133883,0.000028566023],"genre_scores_gemma":[0.99957377,0.0000469372,0.000067680885,0.00027973586,0.0000061003375,0.0000030436236,4.5042412e-7,0.0000030579222,0.000019218938],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99903625,0.00021389531,0.00028363353,0.00015550086,0.0002181791,0.00009255507],"domain_scores_gemma":[0.99958354,0.000098003875,0.0002222903,0.00005007074,0.000016846416,0.00002927148],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023362754,0.000050365812,0.000094304014,0.0002640608,0.00007590419,0.00002147611,0.00007384137,0.000015288722,0.0000042363104],"category_scores_gemma":[0.00027937224,0.00005069446,0.000012269279,0.00043253423,0.00011835295,0.00037735148,0.00003707596,0.00016046001,4.6752263e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006008322,0.000084871754,0.0051741353,0.0000077651985,6.3017886e-8,0.000014106283,0.00055402814,0.0014794758,0.9917143,0.00014434264,0.000038315575,0.00072848925],"study_design_scores_gemma":[0.0018948513,0.00093944056,0.93953,0.000046979887,0.0000020748134,0.00060652517,0.0008437254,0.003957513,0.04894684,0.003047923,0.00007468557,0.00010940024],"about_ca_topic_score_codex":0.0000024370436,"about_ca_topic_score_gemma":0.00000851671,"teacher_disagreement_score":0.9427675,"about_ca_system_score_codex":0.000022805705,"about_ca_system_score_gemma":0.000034232355,"threshold_uncertainty_score":0.206726},"labels":[],"label_agreement":null},{"id":"W4295077933","doi":"10.1038/s41386-022-01449-4","title":"Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter","year":2022,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Simon Fraser University; Centre for Addiction and Mental Health","funders":"Advanced Innovation Center for Human Brain Protection, Capital Medical University; Centre for Addiction and Mental Health","keywords":"Escitalopram; Serotonin transporter; Antidepressant; Citalopram; Serotonin; Internal medicine; Endocrinology; Pharmacology; Transporter; Psychology; Chemistry; Biology; Hippocampus; Medicine; Receptor; Biochemistry","score_opus":0.0171744491457433,"score_gpt":0.26719650003614603,"score_spread":0.25002205089040275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295077933","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936759,0.00006586604,0.000017819653,0.0019182896,0.0021925305,0.00135695,0.000039215483,0.00012520401,0.00060825906],"genre_scores_gemma":[0.99324805,0.00006295555,0.000022279612,0.006292156,0.000051321,0.00018732461,0.0000026290581,0.00004758555,0.000085705666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99695754,0.0010977369,0.00042298343,0.0006373893,0.00043671447,0.00044763647],"domain_scores_gemma":[0.9989983,0.00027819717,0.0002711818,0.00036897213,0.000022705108,0.000060643586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016445197,0.00024367963,0.00030278103,0.000081753016,0.0004615751,0.000013998226,0.0007332307,0.000052115673,0.0004738323],"category_scores_gemma":[0.00005111265,0.0001982522,0.00017954649,0.000613134,0.0002365643,0.00016828442,0.00020097864,0.0005809771,0.000011166647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003069131,0.0005215615,0.0019041029,0.0001162319,0.000013781325,0.000060967322,0.00081958197,0.00197578,0.99314386,0.00017278378,0.0002483336,0.00071609823],"study_design_scores_gemma":[0.0026108741,0.00028478043,0.09241702,0.0000132678815,0.00002601365,0.00007396557,0.000026094718,0.0018714251,0.89934605,0.00017081406,0.0029775077,0.00018216099],"about_ca_topic_score_codex":0.000021853923,"about_ca_topic_score_gemma":0.0000022605784,"teacher_disagreement_score":0.09379779,"about_ca_system_score_codex":0.000028675957,"about_ca_system_score_gemma":0.000034846267,"threshold_uncertainty_score":0.808449},"labels":[],"label_agreement":null},{"id":"W4295279455","doi":"10.1016/j.toxlet.2022.07.161","title":"SOC-IV-04 DAMPening the immune response to clozapine: the role of reactive metabolites in idiosyncratic drug reactions","year":2022,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Clozapine; Pharmacology; Drug; Immune system; Medicine; Chemistry; Immunology; Schizophrenia (object-oriented programming); Psychiatry","score_opus":0.012486847207741302,"score_gpt":0.2522281151853097,"score_spread":0.2397412679775684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295279455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92534393,0.00025558405,0.000012670783,0.07312303,0.0002503407,0.00051470206,0.000015779748,0.00003733497,0.00044662543],"genre_scores_gemma":[0.98390955,0.000011065917,0.000048249283,0.015439571,0.000028120616,0.00028031803,0.0000012978594,0.00001882478,0.0002630327],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965589,0.0021352468,0.0003412969,0.00034393795,0.00026075705,0.00035986514],"domain_scores_gemma":[0.9966042,0.0026897534,0.00017223696,0.0004846759,0.000011885047,0.000037230144],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001232166,0.00014585043,0.00022707666,0.00020471525,0.00054190896,0.00002240437,0.0007253801,0.000030457433,0.00021766967],"category_scores_gemma":[0.0013294297,0.00010309125,0.00010040385,0.00085813884,0.00034299778,0.000102220365,0.0003166703,0.0005741753,0.00002731696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000617935,0.000085291555,0.00012628995,0.000002086006,0.000011491537,0.000011663276,0.005406512,0.000813224,0.9898078,0.0017929319,0.0008192044,0.000505597],"study_design_scores_gemma":[0.000794129,0.00014589002,0.026439713,0.000007825576,0.000020296677,0.00005744228,0.009885409,0.00017689374,0.8891002,0.001190047,0.071971275,0.00021086546],"about_ca_topic_score_codex":0.00011257087,"about_ca_topic_score_gemma":0.0000385462,"teacher_disagreement_score":0.10070756,"about_ca_system_score_codex":0.00010854626,"about_ca_system_score_gemma":0.000079015575,"threshold_uncertainty_score":0.42039394},"labels":[],"label_agreement":null},{"id":"W4295338794","doi":"10.1016/j.cccb.2022.100151","title":"Inflammatory biomarkers and motoric cognitive risk syndrome: Multicohort survey","year":2022,"lang":"en","type":"article","venue":"Cerebral Circulation - Cognition and Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Institut Universitaire de Gériatrie de Montréal; Jewish General Hospital","funders":"Japan Society for the Promotion of Science; Medical Research Council; National Institutes of Health; National Center for Geriatrics and Gerontology; National Health and Medical Research Council; Japan Agency for Medical Research and Development; National Institute on Aging; Ministry of Health, Labour and Welfare; Glenn Foundation for Medical Research; American Federation for Aging Research","keywords":"Medicine; Internal medicine; Odds ratio; C-reactive protein; Dementia; Confidence interval; Cognitive decline; Confounding; Disease; Geriatrics; Vascular dementia; Gerontology; Physical therapy; Inflammation; Psychiatry","score_opus":0.03357774694530683,"score_gpt":0.26445931450061955,"score_spread":0.23088156755531272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295338794","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980106,0.00006290908,0.000080204285,0.00002354367,0.00022825123,0.00075720076,0.000499071,0.00011440516,0.00022384881],"genre_scores_gemma":[0.99917597,0.000025029667,0.000016673694,0.00024571188,0.000014522499,0.00023054515,0.00019625228,0.000024187695,0.00007108177],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99816537,0.0005306448,0.00024861866,0.0005045406,0.00032834813,0.0002224752],"domain_scores_gemma":[0.9992649,0.00028572668,0.00015444071,0.000100193116,0.000058419624,0.00013635056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003146229,0.00017532457,0.00015541456,0.000209384,0.00075051095,0.00008627121,0.000069465976,0.000062618405,0.0008531829],"category_scores_gemma":[0.00035591118,0.00019484478,0.000049110335,0.0003626851,0.00020135564,0.00026874477,0.000103943785,0.00022614852,0.000021247488],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014337296,0.0004104113,0.94784755,0.000032993838,0.00002372014,0.0000690252,0.00041022492,0.0000061889423,0.024566932,0.00008728807,0.00005872624,0.026343562],"study_design_scores_gemma":[0.0017429424,0.000088186185,0.9952822,0.000009314048,0.000095633215,0.00017298464,0.00036436942,0.00050695654,0.0012608735,0.0001701778,0.00003767816,0.0002687304],"about_ca_topic_score_codex":0.00006138318,"about_ca_topic_score_gemma":0.000020727373,"teacher_disagreement_score":0.0474346,"about_ca_system_score_codex":0.000038993276,"about_ca_system_score_gemma":0.000032530326,"threshold_uncertainty_score":0.93417543},"labels":[],"label_agreement":null},{"id":"W4295472516","doi":"10.1038/s41398-022-02142-2","title":"Transdiagnostic inflammatory subgroups among psychiatric disorders and their relevance to role functioning: a nested case-control study of the ALSPAC cohort","year":2022,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Regional Development Fund; University of Bristol; National Institute for Health and Care Research; Science Foundation Ireland; University Hospitals Bristol NHS Foundation Trust; Health Research Board; Canadian Institute for Theoretical Astrophysics; Health Service Executive; Wellcome Trust; Medical Research Council; Wellcome","keywords":"Medicine; Major depressive disorder; Schizophrenia (object-oriented programming); Psychiatry; Cohort; Clinical psychology; Internal medicine; Mood","score_opus":0.007010549944994399,"score_gpt":0.21514278618882504,"score_spread":0.20813223624383065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295472516","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926324,0.0004883852,0.00050754397,0.00296135,0.000898037,0.0020100547,0.0001536715,0.000076062686,0.0002724856],"genre_scores_gemma":[0.9988357,0.000010822535,0.000045559107,0.00068070844,0.00007019643,0.00028498855,0.0000025231072,0.000036236426,0.000033275726],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.997816,0.0004414322,0.00043724498,0.0005536462,0.0004778492,0.00027382062],"domain_scores_gemma":[0.9987076,0.0006617215,0.00015127806,0.00035640938,0.000023153405,0.00009985299],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027939017,0.00024217188,0.00023094562,0.00018590267,0.00077134895,0.000027978276,0.0003180693,0.000047900718,0.00012977772],"category_scores_gemma":[0.000080974045,0.00019916585,0.00013758209,0.0009784002,0.00013378996,0.0001542337,0.000030451776,0.00035729454,0.0000025336228],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033551326,0.00082090724,0.96526444,0.000030144782,0.000048566937,0.000004219164,0.005890565,0.023605447,0.0011094492,0.0012358937,0.00016346079,0.0014913819],"study_design_scores_gemma":[0.0028117555,0.0003694482,0.985206,0.000008689602,0.000059692826,0.00007508355,0.005619516,0.0014792517,0.000035650028,0.0037707088,0.0003073831,0.00025682253],"about_ca_topic_score_codex":0.00008015697,"about_ca_topic_score_gemma":0.0021706775,"teacher_disagreement_score":0.022126196,"about_ca_system_score_codex":0.000017768507,"about_ca_system_score_gemma":0.0001134308,"threshold_uncertainty_score":0.81217474},"labels":[],"label_agreement":null},{"id":"W4296371730","doi":"10.5498/wjp.v12.i9.1264","title":"Why do we not reverse the path? Stress can cause depression, reduction of brain-derived neurotrophic factor and increased inflammation","year":2022,"lang":"en","type":"article","venue":"World Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Impact","funders":"","keywords":"Inflammation; Neurotrophic factors; Depression (economics); Medicine; Brain-derived neurotrophic factor; Tumor necrosis factor alpha; Chronic stress; Dementia; Systemic inflammation; Internal medicine; Proinflammatory cytokine; Endocrinology; Bioinformatics; Disease; Biology; Receptor","score_opus":0.01619984301990031,"score_gpt":0.24458412954701408,"score_spread":0.2283842865271138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296371730","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.958649,0.00051458285,0.000016122687,0.039219737,0.0013118065,0.00018611363,0.000045291563,0.000013006927,0.000044357],"genre_scores_gemma":[0.9967297,0.00021922063,0.00012076689,0.0026017237,0.0002492581,0.0000058752735,9.292021e-7,0.000018247403,0.000054319076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981573,0.00052912853,0.00046219016,0.00019811919,0.00049246504,0.00016078702],"domain_scores_gemma":[0.99871004,0.00015791177,0.0007431567,0.00023920558,0.000055388555,0.00009429657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020611963,0.00013500644,0.0001808637,0.00026950747,0.00034824965,0.00004252101,0.000312237,0.000025578838,0.00018802995],"category_scores_gemma":[0.00020492771,0.000100972,0.000100705285,0.00045982463,0.0001240081,0.00017904995,0.00009202548,0.00047797288,5.1914304e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086007034,0.00022892827,0.008779457,0.000090520676,0.000033663204,0.000033342163,0.0019460933,0.0006347141,0.95635927,0.0008639998,0.025540384,0.0046295454],"study_design_scores_gemma":[0.016945153,0.002205538,0.37230933,0.0013559246,0.00036081285,0.003443048,0.013366396,0.00054048887,0.47722003,0.019023545,0.09149822,0.0017315178],"about_ca_topic_score_codex":0.000056933583,"about_ca_topic_score_gemma":0.00013917024,"teacher_disagreement_score":0.47913924,"about_ca_system_score_codex":0.000030250178,"about_ca_system_score_gemma":0.00014621286,"threshold_uncertainty_score":0.41175187},"labels":[],"label_agreement":null},{"id":"W4296741067","doi":"10.3390/antiox11101870","title":"Oxidative Stress and Emergence of Psychosis","year":2022,"lang":"en","type":"review","venue":"Antioxidants","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fondation Bettencourt Schueller; Agence Nationale de la Recherche","keywords":"Oxidative stress; Psychosis; Biology; Psychology; Psychiatry; Biochemistry","score_opus":0.0895339865461873,"score_gpt":0.3542442500883427,"score_spread":0.26471026354215543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296741067","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00074689265,0.99528086,0.000008802129,0.000008524674,0.00032685453,0.00040233246,0.00034526852,0.000034920675,0.0028455348],"genre_scores_gemma":[0.0007456026,0.99876314,0.00003926217,0.000050773484,0.000021387394,0.000053626103,0.000009919449,0.00003334685,0.00028295352],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981711,0.000310472,0.0004098935,0.00057434844,0.00029911124,0.00023510972],"domain_scores_gemma":[0.99872124,0.0004853686,0.00037961733,0.00034161488,0.000010225058,0.00006193414],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011254958,0.00027236686,0.0007891049,0.00018454668,0.00011372426,0.000017476405,0.00046131032,0.000102547056,0.0013954072],"category_scores_gemma":[0.00037720214,0.00023631672,0.0002109654,0.00062353094,0.0001820523,0.000099213554,0.00020610081,0.00027590786,0.00002931483],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000036792908,0.0001431022,0.000017077944,0.00571263,0.000027503509,0.000012083162,0.00012580371,8.085773e-8,0.0004977561,0.00049177284,0.0011624742,0.99180603],"study_design_scores_gemma":[0.00013029158,0.00007068093,0.000038394413,0.0023385435,0.00007267531,0.000014234411,0.00011328319,0.0000012190014,0.0019783631,0.00013335278,0.9947862,0.00032275022],"about_ca_topic_score_codex":0.000014128887,"about_ca_topic_score_gemma":0.0000047562044,"teacher_disagreement_score":0.99362373,"about_ca_system_score_codex":0.000008958987,"about_ca_system_score_gemma":0.000055896173,"threshold_uncertainty_score":0.99951744},"labels":[],"label_agreement":null},{"id":"W4297097658","doi":"10.1101/2022.09.23.509254","title":"Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Medical Research Council; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Alliance de recherche numérique du Canada; Health Canada; Canada First Research Excellence Fund; Government of Canada; Fondation Brain Canada; McGill University","keywords":"Transcriptome; Biology; Cell type; Dorsolateral prefrontal cortex; Microglia; Parvalbumin; Prefrontal cortex; Major depressive disorder; Gene; Neuroscience; Depression (economics); Gene expression; Cell; Genetics; Inflammation; Amygdala; Cognition","score_opus":0.04196300995588469,"score_gpt":0.23260456612704017,"score_spread":0.19064155617115547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297097658","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99110055,0.0068458808,0.00008203295,0.000099803925,0.00039618235,0.00059712236,0.0006938367,0.00016589616,0.000018722229],"genre_scores_gemma":[0.99447405,0.004913222,0.00019826286,0.00008404093,0.00013357053,0.00008589216,0.0000010233288,0.00009693976,0.000012972964],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99695396,0.00027220193,0.00043784006,0.0014785428,0.00032212728,0.00053530675],"domain_scores_gemma":[0.9985943,0.00023446506,0.00024907617,0.00066573895,0.000040299037,0.00021611259],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021577686,0.0005751687,0.0006068714,0.00028161026,0.00022696136,0.0002710577,0.00062351173,0.00029092998,0.0001045111],"category_scores_gemma":[0.000049518014,0.0005615926,0.000079328376,0.0003162988,0.00022729576,0.00013058513,0.0006552571,0.00070033444,0.000009491157],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029014243,0.00007107471,0.46515274,0.00035670245,0.0000058597493,0.000032565753,0.00002197693,0.000003648833,0.53427714,0.000015375866,0.000021338648,0.000012598106],"study_design_scores_gemma":[0.0003525234,0.000040058843,0.6409611,0.000086144224,0.000022579568,2.3823562e-8,0.000014387447,0.00004084258,0.35714144,0.0000052731007,0.0008672102,0.00046842018],"about_ca_topic_score_codex":0.00005082402,"about_ca_topic_score_gemma":0.000010465489,"teacher_disagreement_score":0.17713569,"about_ca_system_score_codex":0.00006810682,"about_ca_system_score_gemma":0.00011341887,"threshold_uncertainty_score":0.99968356},"labels":[],"label_agreement":null},{"id":"W4297460105","doi":"10.1002/brb3.2753","title":"Exploring the association of interleukin polymorphisms with aggression and internalizing behaviors in children and adolescents","year":2022,"lang":"en","type":"article","venue":"Brain and Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Aggression; Single-nucleotide polymorphism; Anxiety; Clinical psychology; Association (psychology); Psychology; SNP; Genotype; Medicine; Psychiatry; Gene; Genetics; Biology","score_opus":0.02612410044699079,"score_gpt":0.24585389600001548,"score_spread":0.2197297955530247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297460105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992823,0.000116133146,0.0000018377547,0.00025759081,0.00005819679,0.00024754874,0.000014976727,0.000013945419,0.000007491964],"genre_scores_gemma":[0.9995456,0.00008076099,0.000010669827,0.00020777457,0.000008459235,0.00006630677,0.0000017296126,0.000011015728,0.000067687986],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99914825,0.00012893502,0.0001396168,0.00023259192,0.00020689308,0.0001437181],"domain_scores_gemma":[0.9997018,0.000061948005,0.000112600675,0.000082356586,0.000005307697,0.000035981808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018626376,0.00009302886,0.000107612024,0.000103973,0.00014697188,0.00003485966,0.00010283738,0.000017732182,0.000009634111],"category_scores_gemma":[0.000048391987,0.000068048364,0.000015688316,0.00015190576,0.00008277918,0.00013931583,0.0001942383,0.00018623297,1.6555366e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004919242,0.00012780842,0.87438625,0.0000058835167,0.0000013924587,0.000008535862,0.0014422123,6.005407e-7,0.09332732,0.000027350761,0.000018832148,0.030604595],"study_design_scores_gemma":[0.0009301765,0.0001249687,0.9819127,0.0001284616,0.000013540361,0.000054795,0.00051883596,0.0000070782858,0.016185502,0.000008035937,0.000024331215,0.00009158585],"about_ca_topic_score_codex":0.00014654426,"about_ca_topic_score_gemma":0.000049498038,"teacher_disagreement_score":0.107526414,"about_ca_system_score_codex":0.00003331035,"about_ca_system_score_gemma":0.000008474781,"threshold_uncertainty_score":0.27749318},"labels":[],"label_agreement":null},{"id":"W4297461107","doi":"10.1007/978-1-0716-2643-6_11","title":"An (Immuno) Fluorescence Protocol for Monitoring Monoamine Oxidase A/B Protein Distribution Within the Cell","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Monoamine oxidase; Compartmentalization (fire protection); Immunofluorescence; Mitochondrion; Biology; Green fluorescent protein; Subcellular localization; Cell biology; Protein subcellular localization prediction; Biochemistry; Endogeny; Fusion protein; Monoamine oxidase B; Cell; Antibody; Enzyme; Chemistry; Recombinant DNA; Gene; Genetics","score_opus":0.04272309682716518,"score_gpt":0.40493261645271283,"score_spread":0.36220951962554765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297461107","genre_codex":"methods","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12825654,0.000020342108,0.7859797,0.0002736052,0.00023955967,0.08501121,0.00005882924,0.00008613738,0.000074080446],"genre_scores_gemma":[0.16060589,4.2522015e-7,0.34858352,0.00025348476,0.00004365875,0.49036437,0.000021227954,0.00003519507,0.00009221105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956165,0.0031046376,0.0002968178,0.00051891827,0.0001173707,0.00034577557],"domain_scores_gemma":[0.99906194,0.00026321612,0.0001453896,0.00046792143,0.00002128719,0.000040246916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015716706,0.00016471735,0.00016468418,0.00006379271,0.00033704762,0.000029767147,0.0006944053,0.00007075894,0.000020236803],"category_scores_gemma":[0.0008959688,0.00012847062,0.00007137934,0.00042522987,0.0001710622,0.000046687914,0.00020638753,0.00035418815,0.0000013416442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016572204,0.00018020098,0.00010915747,0.00001977392,0.0000013711269,0.000007919023,0.00012276597,0.0002906542,0.9877803,0.0046493695,0.00000609262,0.006666729],"study_design_scores_gemma":[0.00091303454,0.00052128406,0.00013180826,0.000006427527,0.0000018153034,0.000005535918,0.00014485992,0.0027123704,0.984458,0.007471441,0.0034737883,0.00015958023],"about_ca_topic_score_codex":0.000025314072,"about_ca_topic_score_gemma":8.980696e-7,"teacher_disagreement_score":0.43739617,"about_ca_system_score_codex":0.0000760583,"about_ca_system_score_gemma":0.00005760104,"threshold_uncertainty_score":0.523888},"labels":[],"label_agreement":null},{"id":"W4297893144","doi":"10.21203/rs.3.rs-2031269/v1","title":"Efficacy of Lycium Barbarum Polysaccharide on Cytokine Response in Youths with Subthreshold Depression","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"National Natural Science Foundation of China; Guangzhou Medical University","keywords":"Placebo; Medicine; Randomized controlled trial; Depression (economics); Internal medicine; Psychological intervention; Cytokine; Immune system; Antidepressant; Anxiety; Physical therapy; Immunology; Psychiatry; Pathology","score_opus":0.07733875166096278,"score_gpt":0.37683817357654764,"score_spread":0.2994994219155849,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297893144","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932666,0.00021036263,0.000013402567,0.0010270833,0.00017060246,0.0018037994,0.00036219676,0.000105685904,0.0030403098],"genre_scores_gemma":[0.99844766,0.000111901834,0.00003930085,0.00013351839,0.00006119164,0.00030525652,0.000029666106,0.00009619373,0.00077529676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9912297,0.0028522422,0.0005269673,0.0015360039,0.002813433,0.0010416283],"domain_scores_gemma":[0.9944915,0.0032475893,0.00019727748,0.0016961027,0.00012243525,0.0002450556],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0025088831,0.00040760858,0.00055142114,0.0017586797,0.00027821428,0.00010969182,0.0015936976,0.0002884096,0.00087479805],"category_scores_gemma":[0.0048374725,0.00034225517,0.00018337167,0.0016837937,0.00045245237,0.000096901924,0.0019067554,0.0034443387,0.000043109405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.10354406,0.0032797887,0.016290158,0.0011651875,0.000031603297,0.0016335108,0.004972352,0.013231503,0.8506288,0.00090770563,0.001869792,0.002445568],"study_design_scores_gemma":[0.007003772,0.0035808051,0.2619446,0.0027083254,0.000011214581,0.000018641516,0.00295388,0.0007419591,0.716866,0.0008419886,0.0022865566,0.001042257],"about_ca_topic_score_codex":0.00030112657,"about_ca_topic_score_gemma":0.0000721623,"teacher_disagreement_score":0.24565443,"about_ca_system_score_codex":0.00037511284,"about_ca_system_score_gemma":0.0008413156,"threshold_uncertainty_score":0.99990296},"labels":[],"label_agreement":null},{"id":"W4297899746","doi":"10.3389/fmolb.2022.897929","title":"Systemic tryptophan homeostasis","year":2022,"lang":"en","type":"review","venue":"Frontiers in Molecular Biosciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Walloon excellence in life sciences and biotechnology; Fondation contre le Cancer; Fonds De La Recherche Scientifique - FNRS; Université Catholique de Louvain; European Commission; Ministère de l'Économie, de la Science et de l'Innovation - Québec; Ludwig Institute for Cancer Research","keywords":"Tryptophan; Kynurenine; Catabolism; Kynurenic acid; Kynurenine pathway; Biochemistry; Xanthurenic acid; Biology; Chemistry; Metabolism; Amino acid","score_opus":0.0383690097179738,"score_gpt":0.29479072661171174,"score_spread":0.25642171689373794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297899746","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000052888605,0.9920301,0.0010684896,0.000029155515,0.0035459076,0.0010373772,0.00008690798,0.000118712676,0.0020304592],"genre_scores_gemma":[0.00012019229,0.9978072,0.0011170701,0.00030848949,0.00003794643,0.00030014766,0.000016470258,0.00006552704,0.00022695491],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99478924,0.0010055368,0.0007597294,0.0015825619,0.0010222559,0.0008406847],"domain_scores_gemma":[0.99849546,0.00017646511,0.00043208554,0.00072108913,0.000008208369,0.00016668909],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005131408,0.00061131775,0.0015143517,0.0013500425,0.00032094555,0.0002003845,0.0025036319,0.0002584599,0.00019262104],"category_scores_gemma":[0.00070130185,0.00052900874,0.00061307475,0.0040033115,0.0006033365,0.00017595271,0.0004192173,0.0006585301,0.000044058936],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000032251778,0.000081211205,0.000004128632,0.0021603496,0.000011002186,0.00033107278,0.00009263376,0.0000052214446,0.00019377744,0.00045796414,0.0016041235,0.9950553],"study_design_scores_gemma":[0.00017612935,0.00007145374,5.109226e-7,0.0012930107,0.000045849225,0.00012565465,0.00039324476,0.000024236857,0.00045661195,0.00035816716,0.9963883,0.000666839],"about_ca_topic_score_codex":0.000011560661,"about_ca_topic_score_gemma":0.0000015104104,"teacher_disagreement_score":0.9947842,"about_ca_system_score_codex":0.0003235814,"about_ca_system_score_gemma":0.0005195767,"threshold_uncertainty_score":0.99971616},"labels":[],"label_agreement":null},{"id":"W4297980326","doi":"10.21203/rs.3.rs-2067393/v1","title":"Reliable biomarkers for decreased spatial navigation in the Young People with Obesity: Increased serum CRP and QUIN levels","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Kynurenine; Quinolinic acid; Kynurenic acid; Obesity; Montreal Cognitive Assessment; Kynurenine pathway; Internal medicine; Medicine; Cognitive flexibility; Leptin; Cognition; Endocrinology; Psychology; Tryptophan; Psychiatry; Cognitive impairment; Biology; Biochemistry","score_opus":0.05802331131987589,"score_gpt":0.3529198187052691,"score_spread":0.29489650738539325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297980326","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926226,0.00014929584,0.00022724678,0.0014734613,0.00012386919,0.0038598033,0.0006065203,0.00006262382,0.0008745686],"genre_scores_gemma":[0.99773324,0.000077246405,0.0001736137,0.00012992143,0.000075817414,0.0014240934,0.0001956216,0.00004865044,0.0001417926],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99518335,0.0013908787,0.00027566915,0.0009816213,0.0014374902,0.00073101046],"domain_scores_gemma":[0.9971559,0.001737347,0.000114546696,0.0006893595,0.00015274133,0.00015011869],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027121129,0.0002686457,0.0002989736,0.0004182775,0.0007182079,0.00037940053,0.000793479,0.00017640911,0.00015430755],"category_scores_gemma":[0.0015455801,0.00020633363,0.000087907305,0.0009900299,0.00027418698,0.00014014677,0.00069812004,0.0011334443,0.0000053073595],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010827933,0.0043664053,0.83398026,0.013515099,0.00021175623,0.00096299924,0.03274437,0.0013884485,0.0709534,0.004952886,0.012197385,0.013899056],"study_design_scores_gemma":[0.0053713247,0.0013036085,0.9407634,0.0010864872,0.000029244868,0.00006653332,0.011880493,0.010463948,0.015225543,0.0101807,0.0026754271,0.0009532966],"about_ca_topic_score_codex":0.009768876,"about_ca_topic_score_gemma":0.0048277755,"teacher_disagreement_score":0.10678313,"about_ca_system_score_codex":0.0002253504,"about_ca_system_score_gemma":0.00071728,"threshold_uncertainty_score":0.99682516},"labels":[],"label_agreement":null},{"id":"W4297996369","doi":"10.30629/2618-6667-2022-20-3-47-56","title":"Markers of Systemic Inflammation in Assessing the Effectiveness of Neurocognitive Rehabilitation in Aged Patients with Mild Cognitive Impairment","year":2022,"lang":"en","type":"article","venue":"Psikhiatriya","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Neurocognitive; Medicine; Rehabilitation; Cognition; Cognitive rehabilitation therapy; Internal medicine; Physical therapy; Psychiatry","score_opus":0.007418392422803129,"score_gpt":0.24555087738978426,"score_spread":0.23813248496698114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297996369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977636,0.000023049333,0.00003501286,0.00003066785,0.000077080425,0.0018302052,0.00003191516,0.000011111361,0.00019740783],"genre_scores_gemma":[0.9996661,0.0000027474603,0.0000196782,0.000025743873,0.0000038950448,0.00025717652,0.000010648666,0.000012406414,0.0000015820436],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9962643,0.002572165,0.0003464,0.00026294225,0.0003979652,0.00015622246],"domain_scores_gemma":[0.9957999,0.003726447,0.00028210008,0.00010892513,0.00006660936,0.000016046331],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010917255,0.00010852552,0.00019293147,0.00027067203,0.000082662635,0.000011164558,0.00013287902,0.000023052347,0.000010129964],"category_scores_gemma":[0.0009905638,0.000085982196,0.000044110926,0.0009678438,0.0001176373,0.00019876234,0.000070301285,0.00018925685,6.102687e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003189502,0.00055208587,0.9630281,0.0005493019,0.000008180272,0.000004029855,0.0037388233,0.0019275413,0.025656631,0.000104507824,0.0000029297705,0.0012384066],"study_design_scores_gemma":[0.003806306,0.00074009626,0.9750386,0.00037665083,0.000009689532,0.0000010969287,0.005625505,0.00020779429,0.013894132,0.00020887863,3.808379e-7,0.00009085966],"about_ca_topic_score_codex":0.00007537108,"about_ca_topic_score_gemma":0.000025157986,"teacher_disagreement_score":0.012010549,"about_ca_system_score_codex":0.00012234597,"about_ca_system_score_gemma":0.00008096136,"threshold_uncertainty_score":0.35062522},"labels":[],"label_agreement":null},{"id":"W4298129434","doi":"10.1016/j.euroneuro.2022.09.003","title":"Pros and cons of esketamine treatment in psychiatry","year":2022,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kingston Health Sciences Centre; Queen's University","funders":"","keywords":"cons; Psychology; Psychiatry; Medicine; Psychotherapist; Computer science","score_opus":0.021846986840684573,"score_gpt":0.2854868502117675,"score_spread":0.2636398633710829,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298129434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9840288,0.0001944362,0.0000022215845,0.0014558394,0.0012709424,0.00047140755,0.000030743835,0.000102676444,0.012442904],"genre_scores_gemma":[0.9955222,0.00017648339,0.000044461693,0.0035688148,0.00005053194,0.000045966957,0.0000015577066,0.000057112586,0.00053286133],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99748933,0.0012590464,0.00031831168,0.0005144055,0.00013650798,0.00028238914],"domain_scores_gemma":[0.99942595,0.00015670167,0.00012752836,0.00020303567,0.0000072064217,0.00007957654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015443645,0.00017022244,0.00020734231,0.00022760055,0.00010596794,0.000008735871,0.0002701092,0.0000124086555,0.0003564225],"category_scores_gemma":[0.00004717229,0.0001678661,0.00005324338,0.00043458783,0.00022085957,0.00004528538,0.00018053876,0.00022972138,0.000019270148],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035635213,0.0010096183,0.0035967128,0.000017123462,0.0000068300715,0.0003117424,0.0004818513,0.00012223423,0.98386,0.0009499315,0.0022879704,0.0069996165],"study_design_scores_gemma":[0.03796947,0.009005149,0.5905292,0.000021185208,0.00007354441,0.0011192441,0.0008213739,0.0009943318,0.047613755,0.000902068,0.3096492,0.0013014884],"about_ca_topic_score_codex":0.000005793856,"about_ca_topic_score_gemma":0.00000396877,"teacher_disagreement_score":0.9362463,"about_ca_system_score_codex":0.000025284635,"about_ca_system_score_gemma":0.000045170284,"threshold_uncertainty_score":0.6845381},"labels":[],"label_agreement":null},{"id":"W4298142737","doi":"10.1002/mco2.165","title":"Systematic metabolic characterization of mental disorders reveals age‐related metabolic disturbances as potential risk factors for depression in older adults","year":2022,"lang":"en","type":"article","venue":"MedComm","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Impact","funders":"National Natural Science Foundation of China","keywords":"Comorbidity; Anxiety; Depression (economics); Metabolome; Metabolic syndrome; Cohort; Psychiatry; Medicine; Psychology; Clinical psychology; Internal medicine; Obesity","score_opus":0.007301639535194524,"score_gpt":0.2334856472646791,"score_spread":0.22618400772948458,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298142737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99545825,0.0010271757,0.00012871456,0.000081480146,0.0006619483,0.0022400361,0.00026682354,0.00006281117,0.00007276188],"genre_scores_gemma":[0.9986054,0.00035514333,0.000016113128,0.000087320775,0.000013712105,0.00049364625,0.00014969958,0.000035264762,0.00024373551],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99732643,0.0007636829,0.0006478481,0.00045776906,0.0004837362,0.00032050838],"domain_scores_gemma":[0.9988228,0.0002457558,0.0005491402,0.0003022281,0.000015274743,0.00006476631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003359433,0.00023075115,0.00056131557,0.0002518513,0.00031674618,0.000030955827,0.00043659715,0.00005914441,0.00015737995],"category_scores_gemma":[0.0005229762,0.00019321965,0.00019755996,0.00060157105,0.00008908137,0.00023200594,0.00015722311,0.00020573022,0.000004620117],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008666259,0.0027078022,0.06376547,0.0044233417,0.00018317121,0.000017281867,0.03275988,0.00060067634,0.88561696,0.0019000841,0.00013988715,0.0070188036],"study_design_scores_gemma":[0.0076117422,0.00023394129,0.8073816,0.0009913521,0.00021807029,0.0000135126365,0.0053413124,0.0040509873,0.17098972,0.0016902843,0.00064008223,0.0008374325],"about_ca_topic_score_codex":0.00013147845,"about_ca_topic_score_gemma":0.000024205037,"teacher_disagreement_score":0.7436161,"about_ca_system_score_codex":0.000025180874,"about_ca_system_score_gemma":0.000019701329,"threshold_uncertainty_score":0.78792685},"labels":[],"label_agreement":null},{"id":"W4298161422","doi":"","title":"Effects of pentoxifylline, 7-nitroindazole, and imipramine on tumor necrosis factor-&alpha; and indoleamine 2,3-dioxygenase enzyme activity in the hippocampus and frontal cortex of chronic mild-stress-exposed rats","year":2013,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Pentoxifylline; Indoleamine 2,3-dioxygenase; Hippocampus; Imipramine; Tumor necrosis factor alpha; Enzyme; Chemistry; Necrosis; Endocrinology; Medicine; Internal medicine; Neuroscience; Pharmacology; Psychology; Biochemistry; Tryptophan; Pathology","score_opus":0.08651419571002507,"score_gpt":0.4202367911057092,"score_spread":0.33372259539568416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298161422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99130917,0.006884492,0.000009701788,0.00008724979,0.00012005851,0.001350604,0.00011609173,0.00001329884,0.00010932138],"genre_scores_gemma":[0.99519885,0.0043747807,0.00001879027,0.0002501495,0.000041729643,0.000050589195,0.0000037457253,0.000036807724,0.000024565206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99714386,0.0005312297,0.00067416363,0.00060161314,0.0006183072,0.0004308462],"domain_scores_gemma":[0.996901,0.0015413129,0.000864662,0.0003780931,0.00008760359,0.00022738181],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004220694,0.0004215739,0.00089195656,0.0005754069,0.0001606214,0.00045156464,0.0010971933,0.0001078281,0.00038819667],"category_scores_gemma":[0.0006138836,0.00031628733,0.000101185535,0.00062394416,0.0005508181,0.001469892,0.0004968287,0.00048512247,0.000001655131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036364511,0.00076426205,0.032024994,0.00042635488,0.00003327022,0.000035436715,0.0004266268,0.000007358589,0.945906,0.000009729109,0.00038657113,0.019615795],"study_design_scores_gemma":[0.0014055173,0.00009454297,0.49685532,0.00025880715,0.000011730968,0.000010448175,0.00004961235,0.00013771684,0.50061405,0.00038074295,0.000012741774,0.00016877642],"about_ca_topic_score_codex":0.0011249826,"about_ca_topic_score_gemma":0.00024076739,"teacher_disagreement_score":0.4648303,"about_ca_system_score_codex":0.00006350739,"about_ca_system_score_gemma":0.00012900392,"threshold_uncertainty_score":0.9999289},"labels":[],"label_agreement":null},{"id":"W4299561008","doi":"","title":"Kynurenine and depressive symptoms in a poststroke population","year":2014,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Depressive symptoms; Kynurenine; Population; Kynurenine pathway; Psychiatry; Medicine; Stroke (engine); Depression (economics); Psychology; Physical medicine and rehabilitation; Cognition; Tryptophan; Biology; Environmental health","score_opus":0.130968778422603,"score_gpt":0.4949565521947984,"score_spread":0.3639877737721954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4299561008","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942268,0.0019978092,0.00013311414,0.00017586478,0.00025591697,0.00034848548,0.000015733493,0.000033169003,0.0028130943],"genre_scores_gemma":[0.99796337,0.0011356059,0.000041828454,0.000578965,0.0000785139,0.00002031583,0.000004631532,0.00003174596,0.00014499927],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9978068,0.00035759463,0.00054261694,0.000498093,0.0004567357,0.00033819638],"domain_scores_gemma":[0.9985294,0.00044967578,0.00047476363,0.00030857176,0.000057213485,0.00018042319],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00044819358,0.00023689905,0.0004712773,0.00067415606,0.00015680955,0.0007098737,0.0012651561,0.00009441624,0.0012184293],"category_scores_gemma":[0.0011363723,0.0002135153,0.000078732824,0.00071792514,0.00013003977,0.0017160978,0.0005188442,0.00029544998,0.00000780324],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000112228474,0.00011590588,0.63073295,0.000027260738,0.000010695041,0.000013750869,0.00010797733,0.00012173139,0.34365627,0.0004062634,0.0011135753,0.023581387],"study_design_scores_gemma":[0.0009297067,0.000013263661,0.9246296,0.00016419085,0.000011057514,0.000016841293,0.0000134289185,0.00041195157,0.066533595,0.00628583,0.0007400155,0.00025049722],"about_ca_topic_score_codex":0.0005936939,"about_ca_topic_score_gemma":0.000117955766,"teacher_disagreement_score":0.29389668,"about_ca_system_score_codex":0.000038990092,"about_ca_system_score_gemma":0.000028231523,"threshold_uncertainty_score":0.9996946},"labels":[],"label_agreement":null},{"id":"W4300960781","doi":"10.3389/fonc.2022.977640","title":"Tryptophan 2,3-dioxygenase may be a potential prognostic biomarker and immunotherapy target in cancer: A meta-analysis and bioinformatics analysis","year":2022,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Kunming Medical University; National Natural Science Foundation of China","keywords":"Meta-analysis; Hazard ratio; Medicine; Oncology; Internal medicine; Cochrane Library; Kynurenine; Biomarker; Cancer; Kynurenine pathway; Systematic review; MEDLINE; Biology; Confidence interval; Tryptophan","score_opus":0.09020965440011665,"score_gpt":0.36111965693958326,"score_spread":0.2709100025394666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4300960781","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034589495,0.9952158,0.0016344364,0.00023079675,0.00039741708,0.0013715945,0.00056704174,0.000038200356,0.00019885997],"genre_scores_gemma":[0.0003125042,0.99171585,0.005863263,0.00061303086,0.000018004277,0.001062949,0.00014978599,0.000048688216,0.00021594609],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9949403,0.0016235353,0.0013419605,0.0010410708,0.0003830135,0.00067014067],"domain_scores_gemma":[0.9978895,0.0006376684,0.0007806489,0.00052554626,0.000016538546,0.00015008889],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00081684394,0.00066308177,0.0055336403,0.0046652965,0.0001612161,0.00009409618,0.000591709,0.0004695111,0.0010692776],"category_scores_gemma":[0.00028708487,0.00054957555,0.001756244,0.0071833725,0.00043999014,0.00016944598,0.00028180925,0.0006852944,0.0000015173092],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013925838,0.00049233047,0.0007605883,0.0018146661,0.07785721,0.00041970966,0.0009916391,0.00014399871,0.000010721733,0.000025018871,0.0012930041,0.91605186],"study_design_scores_gemma":[0.0011064744,0.00019647818,0.0002620283,0.000034297493,0.09850223,0.000036706446,0.0003738149,0.004638488,0.000005575109,0.000110457004,0.8939797,0.0007537454],"about_ca_topic_score_codex":0.00030815223,"about_ca_topic_score_gemma":0.00053430186,"teacher_disagreement_score":0.9152981,"about_ca_system_score_codex":0.00042969923,"about_ca_system_score_gemma":0.00045278794,"threshold_uncertainty_score":0.9998439},"labels":[],"label_agreement":null},{"id":"W4300960975","doi":"10.3389/fimmu.2022.997240","title":"Dynamic changes in metabolites of the kynurenine pathway in Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease: A systematic Review and meta-analysis","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Student Research Committee, Tabriz University of Medical Sciences; Shahid Beheshti University of Medical Sciences","keywords":"Kynurenic acid; Kynurenine; Kynurenine pathway; Parkinson's disease; Medicine; Internal medicine; Quinolinic acid; Disease; Indoleamine 2,3-dioxygenase; Meta-analysis; Endocrinology; Nicotinamide adenine dinucleotide; Tryptophan; Pharmacology; Chemistry; Biochemistry; NAD+ kinase; Amino acid; Enzyme; Glutamate receptor","score_opus":0.04236227607707809,"score_gpt":0.28681210063245255,"score_spread":0.24444982455537445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4300960975","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006205415,0.9942728,0.000004078264,0.0008054414,0.0002343103,0.0037710173,0.0008158942,0.000022825772,0.000011558883],"genre_scores_gemma":[0.0013190608,0.9948955,0.000047177582,0.00042842492,0.0000040482364,0.0029678505,0.0000834412,0.000055670444,0.00019881492],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9927196,0.0037582633,0.001406794,0.001180531,0.0003766357,0.00055817846],"domain_scores_gemma":[0.9969713,0.0005734214,0.0010599054,0.001236975,0.00001701911,0.00014139495],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008159861,0.00069756526,0.0067461478,0.0014762703,0.00009709333,0.000038270264,0.001087494,0.00014139996,0.00014034784],"category_scores_gemma":[0.002026363,0.0004345926,0.001187665,0.0031580694,0.00055978907,0.00011379875,0.0006789947,0.00066085724,0.0000010959438],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015845797,0.0007937316,0.002168566,0.9218339,0.0463842,0.0001775544,0.00046769384,0.000015472759,0.0000062471336,0.0007944078,0.00025628935,0.026943494],"study_design_scores_gemma":[0.000873842,0.000051414187,0.007393792,0.028245928,0.7277587,0.000008591699,0.0002503913,0.00015565692,0.000003430197,0.0009625365,0.23274226,0.0015534773],"about_ca_topic_score_codex":0.00003429683,"about_ca_topic_score_gemma":0.00025314806,"teacher_disagreement_score":0.89358795,"about_ca_system_score_codex":0.000118756776,"about_ca_system_score_gemma":0.00025717446,"threshold_uncertainty_score":0.9998106},"labels":[],"label_agreement":null},{"id":"W4300989555","doi":"","title":"A meta-analysis of lipid peroxidation markers in major depression","year":2015,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Lipid peroxidation; Depression (economics); Meta-analysis; Psychology; Internal medicine; Medicine; Oxidative stress; Economics","score_opus":0.44837823131739857,"score_gpt":0.5356389909900326,"score_spread":0.08726075967263408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4300989555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98691434,0.0057385247,0.00028340606,0.00020262352,0.00021999661,0.00045683308,0.000052996234,0.000025061521,0.0061062397],"genre_scores_gemma":[0.9979746,0.0010084193,0.00017123035,0.0003903824,0.00002810706,0.000038213024,0.0000076213805,0.000028501907,0.000352933],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9962943,0.0007856203,0.0009987644,0.0005717345,0.0010252784,0.00032429505],"domain_scores_gemma":[0.99741554,0.00056244666,0.0010181611,0.0005638617,0.00018977333,0.0002502341],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0017678598,0.00027335933,0.0013212836,0.0020967925,0.00008989003,0.00044128258,0.0022568651,0.00010555344,0.009578272],"category_scores_gemma":[0.001446714,0.00021979505,0.00066888565,0.0037116979,0.0001532332,0.0021181507,0.0006324658,0.0002723639,0.000012388108],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008370521,0.00076676434,0.21950649,0.00006321581,0.007586313,0.000034840836,0.0006536367,0.0028857938,0.7480632,0.000084912754,0.014394104,0.005123682],"study_design_scores_gemma":[0.0014570308,0.000019943163,0.5500209,0.00005861762,0.010919431,0.000005614953,0.00031886678,0.001120083,0.43158993,0.0021600502,0.001796243,0.00053333683],"about_ca_topic_score_codex":0.000689928,"about_ca_topic_score_gemma":0.00018308377,"teacher_disagreement_score":0.33051437,"about_ca_system_score_codex":0.00006874237,"about_ca_system_score_gemma":0.00012381437,"threshold_uncertainty_score":0.9913271},"labels":[],"label_agreement":null},{"id":"W4301205140","doi":"","title":"Cytokines and depression in cancer patients and caregivers","year":2017,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Depression (economics); Cancer; Medicine; Psychology; Oncology; Psychiatry; Internal medicine","score_opus":0.20767551651557317,"score_gpt":0.5229722099218529,"score_spread":0.31529669340627975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4301205140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930389,0.0037305742,0.0000029796274,0.00013364726,0.00038344463,0.00027654038,0.00003228099,0.0000108270015,0.0023908003],"genre_scores_gemma":[0.9856157,0.013960838,0.000011498402,0.00022640602,0.0000385568,0.00001712172,7.4626485e-7,0.000019069621,0.00011008375],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986128,0.00010762231,0.00028118785,0.00042303884,0.0003304274,0.0002449127],"domain_scores_gemma":[0.9988639,0.0001602438,0.00046473194,0.00028901407,0.00006863276,0.00015351566],"candidate_categories":["scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.00019538609,0.00018114877,0.00033420723,0.0003125966,0.0004258297,0.001143559,0.001373807,0.00006648119,0.00058686704],"category_scores_gemma":[0.0008027828,0.00015324038,0.000038830414,0.00017065502,0.00027358352,0.0022704264,0.0010272242,0.00018964219,0.0000014592324],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009997957,0.000085278225,0.8758966,0.000034725235,0.0000060314846,0.000015902542,0.00024268402,0.000007407931,0.09607999,0.000010218546,0.0027521374,0.024769085],"study_design_scores_gemma":[0.0009844893,0.0000050194826,0.9191134,0.00022365067,0.000007256963,0.000001849277,0.000053980904,0.000028035085,0.077525154,0.0007881503,0.0010856626,0.00018336484],"about_ca_topic_score_codex":0.001818366,"about_ca_topic_score_gemma":0.00033488503,"teacher_disagreement_score":0.04321682,"about_ca_system_score_codex":0.000030473877,"about_ca_system_score_gemma":0.00003919409,"threshold_uncertainty_score":0.99989337},"labels":[],"label_agreement":null},{"id":"W4303671971","doi":"10.1101/2022.10.07.511374","title":"Multi-omic modeling of antidepressant response implicates dynamic immune and inflammatory changes in individuals who respond to treatment","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Canada First Research Excellence Fund","keywords":"Major depressive disorder; Non-negative matrix factorization; Computational biology; Antidepressant; DNA methylation; Biomarker; Bioinformatics; Computer science; Medicine; Matrix decomposition; Biology; Gene; Cognition; Psychiatry; Gene expression; Genetics","score_opus":0.02500878135802253,"score_gpt":0.26229980789913593,"score_spread":0.2372910265411134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4303671971","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99497503,0.001527162,0.00010755496,0.000532028,0.0002408289,0.0016911144,0.00073793286,0.00018646005,0.0000018789246],"genre_scores_gemma":[0.99647796,0.001318337,0.0011287943,0.00020254632,0.000024493449,0.00069750816,3.6781464e-7,0.00013907871,0.00001089674],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995799,0.0007668136,0.00078998477,0.001539331,0.0004276202,0.00067725725],"domain_scores_gemma":[0.9974558,0.00040735674,0.00044115397,0.0013817728,0.00008283134,0.00023111628],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011002918,0.00065305695,0.00089255703,0.0012317703,0.00018950105,0.00013318301,0.00082047563,0.00031833607,0.00003481505],"category_scores_gemma":[0.000877328,0.0006969687,0.00012919496,0.0007534403,0.00016821026,0.00012940503,0.001423285,0.0005692464,0.0000081290955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047910016,0.00023695138,0.008864656,0.00017833308,0.000036383582,0.000055106477,0.00023459636,0.0033307464,0.98651797,0.000054658267,0.0000039477654,0.0000075719645],"study_design_scores_gemma":[0.0015820402,0.00022841129,0.45194793,0.00037522646,0.000031927062,6.218703e-8,0.00004589009,0.012515787,0.5320711,0.0000035832152,0.0004223355,0.0007757102],"about_ca_topic_score_codex":0.00013002277,"about_ca_topic_score_gemma":0.000031218904,"teacher_disagreement_score":0.45444685,"about_ca_system_score_codex":0.00044031523,"about_ca_system_score_gemma":0.00045665295,"threshold_uncertainty_score":0.99954814},"labels":[],"label_agreement":null},{"id":"W4306404149","doi":"10.3390/women2040033","title":"Potential Explanatory Models of the Female Preponderance in Very Late Onset Schizophrenia","year":2022,"lang":"en","type":"article","venue":"Women","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Dementia Research Alliance; Toronto Metropolitan University; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Psychosocial; Biopsychosocial model; Schizophrenia (object-oriented programming); Epidemiology; Psychology; Clinical psychology; Psychosis; Age of onset; Medicine; Psychiatry; Disease; Internal medicine","score_opus":0.016633306679167258,"score_gpt":0.2214840294976745,"score_spread":0.20485072281850725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306404149","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979792,0.000046042314,0.000008128729,0.00012538666,0.00022290359,0.0001498395,0.00003987521,0.000022607497,0.0014060185],"genre_scores_gemma":[0.99841416,0.000007510336,0.0000098794335,0.0005756714,0.000008006733,0.000067172856,6.0590855e-7,0.000009565743,0.00090743054],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989804,0.00017379904,0.00014441962,0.00021727454,0.00027065212,0.00021345375],"domain_scores_gemma":[0.99960375,0.000041207808,0.00006607105,0.000257224,0.00000415263,0.000027587594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014396776,0.000070280024,0.00009801021,0.00006413363,0.000134922,0.000010454164,0.00037121694,0.000017629376,0.00020726958],"category_scores_gemma":[0.000035846424,0.00006018186,0.00004066486,0.00030091737,0.000075398406,0.000098912744,0.00022200328,0.00017208299,0.0000055655287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025339862,0.0012591585,0.0062573194,0.00014680752,0.000026810672,0.00021509308,0.034575712,0.2073028,0.7327357,0.00817733,0.002685909,0.004083389],"study_design_scores_gemma":[0.017341048,0.0007764612,0.22438869,0.00012413647,0.000016749522,0.00018356531,0.014904748,0.07317319,0.47357255,0.18489672,0.00860595,0.002016196],"about_ca_topic_score_codex":0.000015015069,"about_ca_topic_score_gemma":0.0000063173507,"teacher_disagreement_score":0.25916314,"about_ca_system_score_codex":0.000060517432,"about_ca_system_score_gemma":0.0000749764,"threshold_uncertainty_score":0.2454145},"labels":[],"label_agreement":null},{"id":"W4307181310","doi":"10.1124/dmd.122.000934","title":"COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics","year":2022,"lang":"en","type":"review","venue":"Drug Metabolism and Disposition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Mental Health & Substance Use Services; University of British Columbia; Beatrice Hunter Cancer Research Institute; Dalhousie University; University of Toronto; Izaak Walton Killam Health Centre","funders":"National Center for Advancing Translational Sciences; University of Texas at Austin; American Society for Pharmacology and Experimental Therapeutics","keywords":"ADME; Pharmacokinetics; Drug metabolism; Drug; Pharmacology; Medicine; Vaccination; Biology; Distribution (mathematics); Virology; Immunology","score_opus":0.03095305697073116,"score_gpt":0.33211222121541695,"score_spread":0.3011591642446858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307181310","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0046167793,0.9913146,0.000017969203,0.0006830749,0.0006032213,0.0013755613,0.00090968434,0.00009894541,0.00038017638],"genre_scores_gemma":[0.0033969653,0.9912704,0.000014357814,0.00426264,0.00034565423,0.0002357047,0.00013145008,0.00007057709,0.00027222157],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99619335,0.0014331322,0.00053192244,0.00095383136,0.0004603138,0.00042743326],"domain_scores_gemma":[0.9971475,0.001567603,0.0003902456,0.00041825863,0.000015882904,0.0004604812],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006960164,0.0007293663,0.0014805584,0.00034352543,0.00081413914,0.00034936148,0.0003756791,0.00011415945,0.000322803],"category_scores_gemma":[0.00048768095,0.00043095913,0.00037831863,0.0005562383,0.00039363574,0.0002741138,0.00032399752,0.0005988339,0.000010755635],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006173602,0.00026244094,0.0000020498398,0.004547123,0.00017123768,0.00004484261,0.003038769,0.0000137870065,0.00026244094,0.021979176,0.008445324,0.96061546],"study_design_scores_gemma":[0.0025811607,0.000015627467,0.000109848384,0.00016515913,0.0011574583,0.00011568404,0.00014094143,0.00005725655,0.00011479119,0.0014667644,0.9935528,0.0005225158],"about_ca_topic_score_codex":0.00018626485,"about_ca_topic_score_gemma":0.000008865735,"teacher_disagreement_score":0.9851075,"about_ca_system_score_codex":0.00003868509,"about_ca_system_score_gemma":0.00015721699,"threshold_uncertainty_score":0.9998142},"labels":[],"label_agreement":null},{"id":"W4307382762","doi":"10.1093/eurpub/ckac129.701","title":"Systemic inflammation and the risk of depression in people with type 2 diabetes","year":2022,"lang":"en","type":"article","venue":"European Journal of Public Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Diabetes mellitus; Type 2 diabetes; Depression (economics); Internal medicine; C-reactive protein; Population; CIDI; Prospective cohort study; Obesity; Cohort; Systemic inflammation; Cohort study; Comorbidity; Inflammation; Endocrinology; Environmental health; National Comorbidity Survey","score_opus":0.02241287984963074,"score_gpt":0.23958987924354333,"score_spread":0.21717699939391258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307382762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965107,0.00064552337,0.00019167316,0.0019984902,0.00009173729,0.0001223827,0.0000024201624,0.0000053789736,0.00043170957],"genre_scores_gemma":[0.9993786,0.00031808295,0.00003586497,0.00021296767,0.000029132862,9.2033525e-7,3.2844844e-7,0.000009401849,0.000014677621],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99284905,0.0062448825,0.00037922696,0.000089341185,0.00028595122,0.00015153454],"domain_scores_gemma":[0.9988739,0.00025978585,0.00065617234,0.00010157345,0.000037144164,0.00007143652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00672469,0.00005181504,0.00015490034,0.00014066519,0.00014793061,0.00002709871,0.00020371264,0.000004017679,0.000017996643],"category_scores_gemma":[0.00076733215,0.000029833674,0.00002124564,0.0004007851,0.0000652741,0.00013422545,0.00007258031,0.00026536983,0.0000010190928],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005586965,0.000325049,0.62195957,0.00044526698,0.0000450123,0.000068559,0.042218667,0.0042261793,0.02552569,0.0021309378,0.0013442083,0.30115217],"study_design_scores_gemma":[0.008112982,0.0016275651,0.97532487,0.00021780437,0.00000942179,0.000357094,0.005870741,0.0017137378,0.0013761058,0.00014688076,0.0050723227,0.00017047327],"about_ca_topic_score_codex":0.000009774744,"about_ca_topic_score_gemma":0.000008270766,"teacher_disagreement_score":0.3533653,"about_ca_system_score_codex":0.000034974146,"about_ca_system_score_gemma":0.00016890449,"threshold_uncertainty_score":0.23306568},"labels":[],"label_agreement":null},{"id":"W4307460402","doi":"10.1016/j.bbih.2022.100543","title":"The acute effects of antimicrobials and lipopolysaccharide on the cellular mechanisms associated with neurodegeneration in pubertal male and female CD1 mice","year":2022,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neurodegeneration; Lipopolysaccharide; Medicine; Antimicrobial; Physiology; Internal medicine; Microbiome; Inflammation; Endocrinology; Biology; Disease; Bioinformatics","score_opus":0.01951829205530502,"score_gpt":0.25392064151687527,"score_spread":0.23440234946157024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307460402","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947574,0.0001224741,0.000019795098,0.003673401,0.00013604798,0.0011913795,0.000053818436,0.000027423854,0.000018248988],"genre_scores_gemma":[0.996226,0.00011308786,0.00002171305,0.0032311934,0.000005350688,0.00012465123,0.000013710518,0.000026060314,0.00023822885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969334,0.0018061919,0.00028791444,0.0003154899,0.0002946684,0.00036231166],"domain_scores_gemma":[0.99783707,0.0014808287,0.0002567336,0.00034301888,0.000017561866,0.00006477211],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001040157,0.00017737097,0.00023419394,0.00009337516,0.001370261,0.00007826262,0.00031840178,0.000042466792,0.000016073594],"category_scores_gemma":[0.0004002296,0.0001237373,0.000035731126,0.00034019593,0.00020632708,0.00009441388,0.00019893203,0.00049275416,7.716326e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079115576,0.00031990843,0.0004576764,0.000020349515,0.0000052206033,0.000020168674,0.0012788012,0.000010691319,0.9944164,0.0022024482,0.000116956755,0.001072254],"study_design_scores_gemma":[0.0015335234,0.0014149213,0.045726094,0.000058115987,0.00002594009,0.000057571455,0.0010747229,0.00016743148,0.94951123,0.00012760576,0.00006370541,0.00023913916],"about_ca_topic_score_codex":0.0007818158,"about_ca_topic_score_gemma":0.0005563932,"teacher_disagreement_score":0.045268416,"about_ca_system_score_codex":0.00006729173,"about_ca_system_score_gemma":0.000120426965,"threshold_uncertainty_score":0.99992985},"labels":[],"label_agreement":null},{"id":"W4307507608","doi":"10.1101/2022.10.24.513258","title":"Sex-specific effects of voluntary wheel running on behavior and the gut microbiota-immune-brain axis in mice","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; McGill University; Douglas Mental Health University Institute; Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Anxiety; Gut–brain axis; Gut flora; Immune system; Open field; Depression (economics); Wheel running; Turnover; Physiology; Elevated plus maze; Mental health; Hippocampus; Medicine; Psychology; Internal medicine; Immunology; Psychiatry","score_opus":0.011853440338999053,"score_gpt":0.21660888062780578,"score_spread":0.20475544028880674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307507608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99342525,0.0027663556,0.000016617518,0.00042263308,0.0011675797,0.0018782911,0.00014823733,0.00015296703,0.000022046115],"genre_scores_gemma":[0.9975522,0.00051060144,0.00023378653,0.00093654107,0.00008831084,0.00052559195,3.584825e-7,0.00012648194,0.00002613056],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99610406,0.0007034401,0.0007132747,0.0013892828,0.0004821827,0.00060778664],"domain_scores_gemma":[0.9969789,0.001047622,0.00049712963,0.0012973424,0.00005930654,0.00011974614],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00089352374,0.00062738644,0.0008249953,0.0004770529,0.00029240802,0.000165507,0.0011461477,0.0003310515,0.000077302364],"category_scores_gemma":[0.0005030468,0.00057502126,0.00022344418,0.0007961677,0.0006274521,0.00011932765,0.0011740621,0.0015653776,0.000016423402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001802765,0.00032038268,0.0028123404,0.00039770603,0.000022050563,0.00012869266,0.00014901429,0.000035279387,0.9947769,0.000865849,0.00030035942,0.000011127873],"study_design_scores_gemma":[0.0028736088,0.000106386724,0.24870043,0.00041891274,0.00003877139,8.024442e-8,0.000029554585,0.000062027495,0.7436046,0.000004520778,0.0034780859,0.00068304903],"about_ca_topic_score_codex":0.00017005212,"about_ca_topic_score_gemma":0.0000047711123,"teacher_disagreement_score":0.25117233,"about_ca_system_score_codex":0.00021313164,"about_ca_system_score_gemma":0.00020935944,"threshold_uncertainty_score":0.99967015},"labels":[],"label_agreement":null},{"id":"W4307869026","doi":"10.3390/microorganisms10112163","title":"Linking Puberty and the Gut Microbiome to the Pathogenesis of Neurodegenerative Disorders","year":2022,"lang":"en","type":"review","venue":"Microorganisms","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Microbiome; Dysbiosis; Neurodegeneration; Gut–brain axis; Immune system; Pathogenesis; Neuroscience; Biology; Stressor; Immunology; Disease; Medicine; Bioinformatics; Internal medicine","score_opus":0.03462519581426154,"score_gpt":0.26825542691440374,"score_spread":0.2336302311001422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307869026","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00050614716,0.9949666,0.00008051794,0.0011765702,0.00057873584,0.0019719964,0.00031933837,0.000051390267,0.00034866517],"genre_scores_gemma":[0.00048369766,0.9963421,0.00008428711,0.0021036426,0.000079128025,0.0001816735,0.00002394382,0.00010592462,0.00059555046],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99676716,0.001188284,0.0005622938,0.0008092236,0.00027433666,0.0003986983],"domain_scores_gemma":[0.99765813,0.0011318738,0.00036754506,0.0007572546,0.000016170434,0.00006905202],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048463242,0.00048369876,0.0009929525,0.00016550938,0.0006735387,0.00013769872,0.0013948911,0.0001237347,0.00023796792],"category_scores_gemma":[0.0003607338,0.00025304646,0.0004091464,0.0011423359,0.0005315735,0.000050342187,0.0009642983,0.00046815243,0.000050997078],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022246979,0.000077962846,8.074706e-7,0.0014086224,0.00004483391,0.000006480319,0.0021733786,0.0000043142404,0.07454193,0.0011171367,0.0013519563,0.9192503],"study_design_scores_gemma":[0.00033029218,0.000045012304,0.000005624025,0.00022625287,0.00013765242,0.000056836412,0.00012519567,0.0000013813901,0.0035497947,0.00013107187,0.99508274,0.00030813093],"about_ca_topic_score_codex":0.000028697883,"about_ca_topic_score_gemma":0.000052429856,"teacher_disagreement_score":0.9937308,"about_ca_system_score_codex":0.000045516186,"about_ca_system_score_gemma":0.00015327237,"threshold_uncertainty_score":0.9999922},"labels":[],"label_agreement":null},{"id":"W4307899055","doi":"10.1016/j.psychres.2022.114938","title":"Changes in inflammatory balance correlates with conversion to psychosis among individuals at clinical high-risk: A prospective cohort study","year":2022,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Capacity Building Plan for some Non-military Universities and Colleges of Shanghai Scientific Committee; Shanghai Clinical Research Center for Mental Health; Science and Technology Commission of Shanghai Municipality; National Natural Science Foundation of China","keywords":"Psychosis; Prospective cohort study; Internal medicine; Medicine; Cohort; Balance (ability); Cytokine; Cohort study; Interleukin 6; Interleukin; Immunology; Psychology; Psychiatry; Physical therapy","score_opus":0.03615640976815265,"score_gpt":0.3506969760171097,"score_spread":0.31454056624895704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307899055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924157,0.000053870128,0.0000017649809,0.0018374736,0.00082226814,0.0040224064,0.000052677886,0.000092982176,0.00070084404],"genre_scores_gemma":[0.996968,0.000069571994,0.000068069865,0.00038442,0.00010244372,0.0017113172,0.000004617497,0.000045762416,0.00064581755],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9934117,0.0023106793,0.0004098535,0.0012943989,0.0017943955,0.0007789242],"domain_scores_gemma":[0.9980426,0.00080053584,0.00015561898,0.00066329626,0.000078834535,0.00025911166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0037119067,0.00022610457,0.00035334827,0.00060539186,0.00094231975,0.00008947897,0.00086590933,0.00008483854,0.0005999257],"category_scores_gemma":[0.00055017084,0.0002019264,0.000057186655,0.002136097,0.0003997767,0.00013131383,0.0009104759,0.0015938089,0.00020072017],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008750823,0.0014362526,0.98834145,0.000017450953,0.00003185085,0.000027246684,0.0014737654,0.000060750568,0.000120933095,0.000109977525,0.0073128156,0.00019241008],"study_design_scores_gemma":[0.002793503,0.0028949687,0.98937064,0.000030083318,0.000009174841,0.0000045877023,0.0034609162,0.000079468446,0.00016082468,0.0002823731,0.00065596116,0.00025748965],"about_ca_topic_score_codex":0.00036076846,"about_ca_topic_score_gemma":0.0039058784,"teacher_disagreement_score":0.0066568544,"about_ca_system_score_codex":0.00025371276,"about_ca_system_score_gemma":0.00015200293,"threshold_uncertainty_score":0.823432},"labels":[],"label_agreement":null},{"id":"W4308039542","doi":"10.1016/j.chom.2022.09.014","title":"Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses","year":2022,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; Université du Québec à Montréal","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Biology; Host (biology); Colonization; Proteobacteria; Metabolism; Microbiology; Bacteria; Genetics; Biochemistry","score_opus":0.01360604318561298,"score_gpt":0.23540082489183078,"score_spread":0.2217947817062178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308039542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99711174,0.00050544925,0.00003279427,0.0006744014,0.0003882977,0.0007031961,0.00034811304,0.00012242877,0.0001136038],"genre_scores_gemma":[0.9946542,0.00010602033,0.00010242796,0.002105837,0.000027211172,0.00008675691,0.000053467218,0.000051566032,0.0028125579],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982379,0.00035254,0.00023788685,0.00059564755,0.0001976771,0.0003783465],"domain_scores_gemma":[0.9993679,0.00008749944,0.00013782502,0.0002767307,0.000025814123,0.0001042301],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001359295,0.00023252178,0.0002120786,0.00012482655,0.00052854774,0.00014247779,0.00031495994,0.000049625447,0.00030302367],"category_scores_gemma":[0.00009138239,0.00024783937,0.000052851407,0.00039442733,0.00020120041,0.00018507168,0.00033811084,0.00023138769,0.0000237119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017752788,0.00018947282,0.0004113996,0.000016060962,0.0000015313459,0.000020565734,0.00046012198,0.000010978118,0.9938723,0.00003298987,0.0046050353,0.00020203012],"study_design_scores_gemma":[0.0011060421,0.00019451352,0.013380289,0.0000048148427,0.000016295255,0.000042203224,0.00014879314,0.00008348187,0.9101906,0.00001958188,0.07449688,0.0003165347],"about_ca_topic_score_codex":0.0000457102,"about_ca_topic_score_gemma":0.0000033733334,"teacher_disagreement_score":0.08368172,"about_ca_system_score_codex":0.000039334078,"about_ca_system_score_gemma":0.00005255917,"threshold_uncertainty_score":0.9999974},"labels":[],"label_agreement":null},{"id":"W4308123922","doi":"10.3389/fimmu.2022.1013784","title":"Dynamic changes in kynurenine pathway metabolites in multiple sclerosis: A systematic review","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"Kynurenine; Quinolinic acid; Kynurenine pathway; Kynurenic acid; Indoleamine 2,3-dioxygenase; Multiple sclerosis; Medicine; Neuroprotection; Immunology; Internal medicine; Pharmacology; Chemistry; Biochemistry; Tryptophan; Glutamate receptor","score_opus":0.05419465928243742,"score_gpt":0.27166725892987936,"score_spread":0.21747259964744195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308123922","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000035501387,0.9937635,0.000012307576,0.0001084258,0.0017097747,0.004109043,0.000094477466,0.00007020824,0.00009676436],"genre_scores_gemma":[0.000068062574,0.99417156,0.00022713964,0.00043384972,0.000009288058,0.004669954,0.000080151876,0.00008796788,0.00025202057],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.99299884,0.0032702447,0.0015472731,0.0010678498,0.00027826725,0.000837499],"domain_scores_gemma":[0.99752283,0.00077903713,0.0007211396,0.0009252738,0.00000962396,0.000042113523],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009451911,0.000670929,0.005047981,0.001902039,0.000070763665,0.000028146822,0.0014763072,0.00039030344,0.0001501405],"category_scores_gemma":[0.0037446097,0.00059211603,0.000381696,0.0027630802,0.00024580906,0.00011321669,0.0004079499,0.0013589174,0.0000394349],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023114013,0.00035531793,0.000020673508,0.7427465,0.00008374187,0.00017927104,0.00034658835,0.0000016699915,0.00011479318,0.0001469944,0.00033453913,0.25564682],"study_design_scores_gemma":[0.0012938227,0.000113260285,0.00004001975,0.5037239,0.0002367591,0.00008086923,0.00041249924,0.00007529185,0.000025290758,0.00017879247,0.4928421,0.0009773817],"about_ca_topic_score_codex":0.000053610365,"about_ca_topic_score_gemma":0.0004724783,"teacher_disagreement_score":0.49250758,"about_ca_system_score_codex":0.0005923787,"about_ca_system_score_gemma":0.0002222785,"threshold_uncertainty_score":0.99965304},"labels":[],"label_agreement":null},{"id":"W4308387600","doi":"10.1016/j.bbih.2022.100554","title":"Neuroinflammation and neuroprogression in depression: Effects of alternative drug treatments","year":2022,"lang":"en","type":"review","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Neuroinflammation; Major depressive disorder; Antidepressant; Inflammation; Medicine; Neuroscience; Proinflammatory cytokine; Animal models of depression; Monoamine neurotransmitter; Psychology; Bioinformatics; Psychiatry; Serotonin; Anxiety; Immunology; Internal medicine; Mood; Biology; Receptor","score_opus":0.06543528563011271,"score_gpt":0.3770993282296537,"score_spread":0.311664042599541,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308387600","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12698258,0.8684714,0.0000013238141,0.000081482496,0.00047472285,0.0037753833,0.000069508475,0.000079872836,0.00006372879],"genre_scores_gemma":[0.0039265244,0.99491066,0.00002984975,0.00018201135,0.000022871549,0.0006019577,0.000100898025,0.00008206755,0.00014318073],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99339986,0.0040138694,0.00090579106,0.0007170062,0.000500849,0.0004626314],"domain_scores_gemma":[0.9960634,0.0020392588,0.0010381113,0.00067682937,0.000012442388,0.00016995383],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004703649,0.0005042175,0.0013291307,0.0005480521,0.00038662978,0.000041175026,0.000573374,0.000121071,0.000051662548],"category_scores_gemma":[0.0006969589,0.0004419472,0.00022299604,0.00075352215,0.00016898483,0.00019443524,0.0004932804,0.0010039465,0.0000057929537],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018140467,0.00063642074,0.000098974284,0.006901937,0.0000046049254,0.000119812896,0.0007515594,4.3254482e-7,0.0002399027,0.000026229,0.00006810902,0.99113387],"study_design_scores_gemma":[0.007379716,0.0023502149,0.031186325,0.03413163,0.000437852,0.00054866244,0.000383916,0.00004074248,0.0035256278,0.00015775744,0.91773945,0.002118112],"about_ca_topic_score_codex":0.0005612608,"about_ca_topic_score_gemma":0.000032950535,"teacher_disagreement_score":0.98901576,"about_ca_system_score_codex":0.00023298505,"about_ca_system_score_gemma":0.00034816223,"threshold_uncertainty_score":0.99980325},"labels":[],"label_agreement":null},{"id":"W4308522392","doi":"10.1038/s41398-022-02234-z","title":"Are the antidepressant effects of insulin-sensitizing medications related to improvements in metabolic markers?","year":2022,"lang":"en","type":"review","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Antidepressant; Insulin; Metformin; Mood; Internal medicine; Psychiatry; Anxiety","score_opus":0.03194473878692256,"score_gpt":0.3161302675003762,"score_spread":0.28418552871345365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308522392","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011307048,0.99340576,0.000032656604,0.0010816169,0.0012670644,0.0018823002,0.00016407567,0.000044137138,0.0009916687],"genre_scores_gemma":[0.0057154065,0.9926693,0.00020689746,0.0009102009,0.000057996822,0.00026648722,0.000055079283,0.00005914176,0.000059519873],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99717194,0.00056132005,0.000826329,0.00055552507,0.0006149598,0.00026991585],"domain_scores_gemma":[0.9978068,0.0011310574,0.0005378562,0.00043521906,0.000014580827,0.00007448308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033649465,0.00030374102,0.00074707594,0.00040959995,0.00017804577,0.00001807377,0.00058440556,0.00013564066,0.00015742978],"category_scores_gemma":[0.00024399093,0.00023286806,0.00036246987,0.001575652,0.00010030753,0.00007532175,0.00006018587,0.00060350937,0.000026470416],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000063441315,0.0007484818,0.0005649754,0.010256914,0.00028278888,0.000022330265,0.0006744593,0.00011554936,0.00016011122,0.020581566,0.00081011694,0.9657193],"study_design_scores_gemma":[0.0017783688,0.000064750144,0.020209495,0.005251357,0.00050643063,0.000033004024,0.00018402257,0.000060350645,0.000044104403,0.0054990207,0.96565264,0.000716457],"about_ca_topic_score_codex":0.000015253127,"about_ca_topic_score_gemma":0.000028789229,"teacher_disagreement_score":0.96500283,"about_ca_system_score_codex":0.000019325265,"about_ca_system_score_gemma":0.00029034136,"threshold_uncertainty_score":0.9496084},"labels":[],"label_agreement":null},{"id":"W4308524607","doi":"10.3390/ijms232113543","title":"Transcriptomic Studies of Antidepressant Action in Rodent Models of Depression: A First Meta-Analysis","year":2022,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill University; Douglas Mental Health University Institute","funders":"Agence Nationale de la Recherche; ERA-Net NEURON","keywords":"Fluoxetine; Antidepressant; Transcriptome; Meta-analysis; Biomarker; Bioinformatics; Major depressive disorder; Depression (economics); Medicine; Neuroscience; Animal studies; Biology; Psychology; Gene; Hippocampus; Cognition; Genetics; Internal medicine; Gene expression; Serotonin","score_opus":0.32770505250969223,"score_gpt":0.42999073622724737,"score_spread":0.10228568371755514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308524607","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0036376151,0.9944783,0.0009553111,0.000106035885,0.00045442235,0.00016309645,0.000044863253,0.0000033673107,0.00015699919],"genre_scores_gemma":[0.16579461,0.8338943,0.00022881936,0.000036731326,0.000013405274,0.000013087695,0.0000010996314,0.000008252747,0.000009711105],"study_design_codex":"simulation_or_modeling","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99569726,0.00048706162,0.0013726972,0.00037830445,0.0019133367,0.00015136595],"domain_scores_gemma":[0.99709857,0.0005384559,0.0019791643,0.00018128955,0.00016094766,0.00004159188],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010887672,0.00022685771,0.0019142333,0.0017753913,0.00006170911,0.000040168645,0.0017955118,0.00005946173,0.00016858],"category_scores_gemma":[0.00037723847,0.00015340596,0.0024857468,0.001383075,0.00036216664,0.00035548554,0.00017700224,0.00028462504,3.8232045e-7],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030139607,0.0026115573,0.00011417229,0.005420266,0.16156149,0.0017053924,0.0048657577,0.4106463,0.00974927,0.0054534595,0.00016357124,0.39740738],"study_design_scores_gemma":[0.0065640574,0.002631621,0.00024115312,0.012730897,0.43662685,0.0030562126,0.009645759,0.0120633915,0.14121307,0.029009085,0.34164637,0.004571506],"about_ca_topic_score_codex":0.000041944953,"about_ca_topic_score_gemma":0.00004866577,"teacher_disagreement_score":0.39858288,"about_ca_system_score_codex":0.000082915285,"about_ca_system_score_gemma":0.00025183117,"threshold_uncertainty_score":0.6255713},"labels":[],"label_agreement":null},{"id":"W4308633769","doi":"10.1007/s11064-022-03808-5","title":"Reversal and Preventive Pleiotropic Mechanisms Involved in the Antipsychotic-Like Effect of Taurine, an Essential β-Amino Acid in Ketamine-Induced Experimental Schizophrenia in Mice","year":2022,"lang":"en","type":"article","venue":"Neurochemical Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Neurochemical; Taurine; Schizophrenia (object-oriented programming); Prepulse inhibition; Internal medicine; Endocrinology; Pharmacology; Dopamine; Risperidone; Psychology; Medicine; Psychiatry; Chemistry; Amino acid; Biochemistry","score_opus":0.03998113454553915,"score_gpt":0.34916807893153023,"score_spread":0.3091869443859911,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308633769","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985786,0.00008256376,0.0000024197413,0.00018919731,0.00009849999,0.00092023227,0.000009247457,0.000013917951,0.00010528972],"genre_scores_gemma":[0.9995429,0.00001822728,0.000035308378,0.0001383744,0.00002125508,0.00019665327,0.000006401744,0.000023408287,0.00001749557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99452263,0.0027471655,0.00034561756,0.0007711257,0.0010327562,0.0005806957],"domain_scores_gemma":[0.99848056,0.0010177655,0.000057375873,0.00033574738,0.00001759463,0.0000909854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010678754,0.00019151757,0.0002859121,0.00046226507,0.00011756543,0.000044323573,0.00085040653,0.0000786347,0.000059765025],"category_scores_gemma":[0.00085881376,0.000164723,0.000054630065,0.0014106681,0.00024534686,0.00016381001,0.0005298699,0.0012851746,0.0000027470212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018432703,0.0007115598,0.00085126166,0.000042987558,0.0000014676232,0.00014135853,0.0012046591,0.0000020834464,0.9945974,0.00032219556,0.000033009543,0.00024879407],"study_design_scores_gemma":[0.0038873428,0.001320631,0.0105624,0.000024756377,0.0000015655497,0.000015278223,0.00088917935,0.00040873385,0.98233235,0.00041453174,0.000010430066,0.00013280916],"about_ca_topic_score_codex":0.00012771664,"about_ca_topic_score_gemma":0.00009614785,"teacher_disagreement_score":0.012265011,"about_ca_system_score_codex":0.0000820721,"about_ca_system_score_gemma":0.00007013618,"threshold_uncertainty_score":0.67172086},"labels":[],"label_agreement":null},{"id":"W4308740910","doi":"10.1016/j.gendis.2022.10.012","title":"Exploration of the common gene and potential molecular mechanisms between Herpes simplex virus 1 infection and Alzheimer's disease","year":2022,"lang":"en","type":"article","venue":"Genes & Diseases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Shenzhen University","keywords":"Herpes simplex virus; Disease; Virology; Gene; Alzheimer's disease; Biology; Virus; Medicine; Genetics; Pathology","score_opus":0.02996933136787584,"score_gpt":0.26080482080644946,"score_spread":0.23083548943857363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308740910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99571264,0.0020480738,0.0010434702,0.0003063895,0.0001131512,0.0003047197,0.00042176206,0.000042759602,0.0000070159026],"genre_scores_gemma":[0.9992433,0.00023391534,0.000016221687,0.00037106924,0.000029049552,0.000059769984,0.000025375479,0.000015279267,0.000006023075],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894536,0.00024401842,0.00013576365,0.0002696285,0.00026998622,0.00013527351],"domain_scores_gemma":[0.99955225,0.000044278964,0.00008844858,0.00019513455,0.000011544921,0.00010832871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004035019,0.00011395248,0.00011260451,0.000050715727,0.0003980038,0.00003898181,0.00011891224,0.000016407474,0.000034765213],"category_scores_gemma":[0.000036487687,0.000097901735,0.00006655017,0.00016480483,0.00012106305,0.0001761279,0.00028190165,0.000042106727,7.9360285e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002965133,0.0005930448,0.014902682,0.000072782466,0.00007692475,0.000040329876,0.00033003863,0.004628191,0.7768119,0.003348815,0.00014893069,0.19874983],"study_design_scores_gemma":[0.0008370262,0.00015083536,0.25018778,0.000008066864,0.00037303555,0.0000050491954,0.00017838104,0.0007777088,0.7062379,0.039110158,0.0018123444,0.00032172253],"about_ca_topic_score_codex":0.00007209555,"about_ca_topic_score_gemma":0.000008364322,"teacher_disagreement_score":0.2352851,"about_ca_system_score_codex":0.000008159729,"about_ca_system_score_gemma":0.000032296957,"threshold_uncertainty_score":0.3992317},"labels":[],"label_agreement":null},{"id":"W4308742338","doi":"10.1016/j.molmed.2022.10.003","title":"Biomarker opportunities in the treatment of cancer-related depression","year":2022,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Biomarker; Depression (economics); Cancer; Medicine; Oncology; Internal medicine; Biology; Genetics","score_opus":0.18599260589746675,"score_gpt":0.40385369704346485,"score_spread":0.2178610911459981,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308742338","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004677457,0.9901524,8.012856e-7,0.0003276463,0.00024455346,0.00037477666,0.000025604015,0.000024226103,0.008382207],"genre_scores_gemma":[0.0009283015,0.9979208,0.0000049473233,0.00019468626,0.000015102499,0.000365484,0.00008178308,0.000033717166,0.0004551651],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973055,0.0008832876,0.0006519317,0.00043290312,0.0004700061,0.00025637122],"domain_scores_gemma":[0.99875426,0.000418317,0.00028834608,0.00049271336,0.0000044227418,0.000041938103],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024738107,0.00033656234,0.0010204852,0.00090145005,0.000040389124,0.0000048150837,0.00050217274,0.00012632737,0.0015580505],"category_scores_gemma":[0.00008649961,0.00018650491,0.00021855535,0.0015826061,0.00020921478,0.000020901802,0.000044119795,0.0002471149,0.0000013894231],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007867494,0.00030592986,0.0000048696747,0.0004820441,0.000021817219,0.0006706389,0.0009775823,0.0000019872768,0.00012836177,0.00014075934,0.00017673655,0.9970814],"study_design_scores_gemma":[0.0010750868,0.00025531018,0.00006736453,0.0021236723,0.0001643626,0.000029106963,0.0002255391,0.000012233589,0.00008990719,0.000047434554,0.99574023,0.0001697205],"about_ca_topic_score_codex":0.0002885835,"about_ca_topic_score_gemma":0.00006309956,"teacher_disagreement_score":0.9969117,"about_ca_system_score_codex":0.00015632361,"about_ca_system_score_gemma":0.00009644911,"threshold_uncertainty_score":0.99935466},"labels":[],"label_agreement":null},{"id":"W4308843890","doi":"10.21203/rs.3.rs-2230675/v1","title":"Concentration Levels of BDNF, PI3K, AKT, and CREB Predict Depressed Mood and Impulsive Behavior in First-Episode Drug- Naive Schizophrenia Patients","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); CREB; Drug-naïve; Mood; Protein kinase B; Psychology; Brain-derived neurotrophic factor; Internal medicine; Positive and Negative Syndrome Scale; Pathogenesis; Neurotrophic factors; Medicine; Psychiatry; Endocrinology; PI3K/AKT/mTOR pathway; Clinical psychology; Drug; Psychosis; Signal transduction; Biology; Receptor; Transcription factor","score_opus":0.04468301088765987,"score_gpt":0.3416603716966973,"score_spread":0.2969773608090374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308843890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938109,0.0006214006,0.000011189583,0.00021297688,0.00015204867,0.0028953538,0.0018637052,0.00004168506,0.0003907384],"genre_scores_gemma":[0.9983117,0.00069255254,0.00007783636,0.00003072474,0.00003543718,0.0006446075,0.00009888621,0.000043392258,0.0000648823],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99534965,0.0009819106,0.00050547364,0.0011364857,0.001384609,0.00064189255],"domain_scores_gemma":[0.99787027,0.0009285659,0.00022158519,0.0005342391,0.000227227,0.00021814114],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005562983,0.00031526887,0.00044747468,0.0004354445,0.00033975052,0.00015142735,0.0005590311,0.00022053452,0.00023560243],"category_scores_gemma":[0.0017590921,0.0003248075,0.0000858804,0.00051620917,0.00060943625,0.00021492518,0.0018802673,0.0014587363,0.0000035729324],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023701335,0.0030792325,0.9409994,0.0037443645,0.000052661493,0.00016310261,0.00940544,0.00063601165,0.018524878,0.0015245348,0.001133498,0.018366754],"study_design_scores_gemma":[0.0047659883,0.0006802427,0.956777,0.00049381214,0.000018223629,0.0000034251582,0.0009222059,0.0011695598,0.03259818,0.0019388098,0.00017207729,0.00046049504],"about_ca_topic_score_codex":0.00068222464,"about_ca_topic_score_gemma":0.0005923412,"teacher_disagreement_score":0.017906258,"about_ca_system_score_codex":0.00017476344,"about_ca_system_score_gemma":0.00022947074,"threshold_uncertainty_score":0.9999204},"labels":[],"label_agreement":null},{"id":"W4309047046","doi":"10.1016/j.semarthrit.2022.152131","title":"Cognitive impairment in the immune-mediated inflammatory diseases compared with age-matched controls: Systematic review and meta-regression","year":2022,"lang":"en","type":"review","venue":"Seminars in Arthritis and Rheumatism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"Medical Research Council; UK Research and Innovation; Manchester Biomedical Research Centre; University of Manchester; National Institute for Health and Care Research; Versus Arthritis","keywords":"Medicine; Verbal fluency test; Cognition; Psoriatic arthritis; Internal medicine; Meta-analysis; Rheumatoid arthritis; Neuropsychological assessment; Neuropsychology; Clinical psychology; Psychiatry","score_opus":0.030516029397331328,"score_gpt":0.28880435393787135,"score_spread":0.25828832454054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309047046","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00048142567,0.9925059,9.1899375e-7,0.00010177874,0.00004940667,0.006437233,0.0003147899,0.000039752915,0.000068807116],"genre_scores_gemma":[0.0051758843,0.9900785,0.000008171561,0.0004962845,0.0000037341174,0.004041322,0.000119324875,0.000045187702,0.00003155548],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9945479,0.0025727465,0.0012927494,0.0006694576,0.0005184259,0.00039870274],"domain_scores_gemma":[0.99528754,0.0034146933,0.0007836469,0.0003961417,0.000014325239,0.00010368236],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009438416,0.0006627961,0.0043710363,0.00024161807,0.00023465231,0.00013340417,0.0003935189,0.000114968905,0.00014459809],"category_scores_gemma":[0.00094909605,0.00034249068,0.00027708014,0.0005401049,0.00042248072,0.00016698857,0.0002002279,0.00059497805,0.000006988147],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042468633,0.00042476977,0.000019090343,0.7946348,0.00044647665,0.0014310755,0.0027750412,4.9261155e-7,0.0000018715064,0.00020448638,0.00029390943,0.19972548],"study_design_scores_gemma":[0.0018151354,0.00018185886,0.00010807537,0.9892449,0.0027208875,0.0005485762,0.0012250574,0.000008922044,7.8977763e-7,0.00009300747,0.0034848538,0.00056797557],"about_ca_topic_score_codex":0.000025894036,"about_ca_topic_score_gemma":0.00006715559,"teacher_disagreement_score":0.1991575,"about_ca_system_score_codex":0.00005357357,"about_ca_system_score_gemma":0.00010257587,"threshold_uncertainty_score":0.9999027},"labels":[],"label_agreement":null},{"id":"W4309099433","doi":"10.1177/02698811221132473","title":"Changes in insulin resistance following antidepressant treatment mediate response in major depressive disorder","year":2022,"lang":"en","type":"article","venue":"Journal of Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"H. Lundbeck A/S","keywords":"Antidepressant; Exacerbation; Major depressive disorder; Internal medicine; Psychology; Rating scale; Depression (economics); Mediation; Medicine; Developmental psychology; Amygdala","score_opus":0.0213012667136168,"score_gpt":0.3219742950723098,"score_spread":0.300673028358693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309099433","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891118,0.003051609,0.000008747346,0.0055673094,0.0017142677,0.0003219898,0.000019902984,0.000012713221,0.00019166821],"genre_scores_gemma":[0.9966527,0.0012277864,0.0000700094,0.0016008526,0.000083260544,0.000097428805,5.671148e-7,0.000024897168,0.0002424798],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.996736,0.0015564972,0.0005734723,0.00034666448,0.00036486075,0.00042253046],"domain_scores_gemma":[0.9984039,0.00089541444,0.00042958494,0.00015134453,0.000018477971,0.000101295234],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007613216,0.00019120492,0.00041466733,0.00077349355,0.0001430555,0.000016730899,0.00047331702,0.000057192618,0.00039951256],"category_scores_gemma":[0.00035266203,0.00017264664,0.00014440042,0.00076864276,0.00007235989,0.0001452956,0.000094169875,0.00051049073,0.000005498238],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.034025963,0.0020216003,0.019757107,0.000017075801,0.000052442225,0.0074889828,0.0036109968,0.00184,0.9252218,0.00003232341,0.0018611887,0.004070548],"study_design_scores_gemma":[0.13880974,0.006526925,0.52805126,0.00018458422,0.00014380773,0.0006198516,0.0051028123,0.00061860506,0.2091507,0.0033621637,0.10601677,0.001412796],"about_ca_topic_score_codex":0.000018321303,"about_ca_topic_score_gemma":0.0004440368,"teacher_disagreement_score":0.71607107,"about_ca_system_score_codex":0.0002696198,"about_ca_system_score_gemma":0.00014718369,"threshold_uncertainty_score":0.7040326},"labels":[],"label_agreement":null},{"id":"W4309343394","doi":"10.21203/rs.3.rs-2238679/v1","title":"First Trimester Human Umbilical Cord Perivascular cells (HUCPVC) Modulate the Kynurenine Pathway and Glutamate Neurotransmission in an LPS-induced Mouse Model of Neuroinflammation","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CReATe Fertility Centre","funders":"Hospital for Sick Children","keywords":"Glutamatergic; Neuroprotection; Neuroinflammation; Kynurenine pathway; Neurotoxicity; Glutamate receptor; Pharmacology; Kynurenine; Chemistry; Lipopolysaccharide; Indoleamine 2,3-dioxygenase; Biology; Biochemistry; Receptor; Inflammation; Immunology; Toxicity; Amino acid","score_opus":0.11940533142889995,"score_gpt":0.36766258950322406,"score_spread":0.2482572580743241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309343394","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99632746,0.00006153656,0.000057525438,0.0007933701,0.00007617127,0.0023492116,0.0001147571,0.00008528439,0.00013465685],"genre_scores_gemma":[0.9988848,0.00028948163,0.000038127997,0.000049338494,0.00004121173,0.00025082342,0.000037389527,0.000089621084,0.0003192183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9934808,0.002252103,0.0006526791,0.0013144399,0.0016012395,0.0006987219],"domain_scores_gemma":[0.99761444,0.0004228529,0.00017587615,0.0014229093,0.00012513959,0.00023879766],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014264775,0.00038982325,0.00048529136,0.00053095113,0.00062174146,0.0002501422,0.001186249,0.00026784025,0.000115487346],"category_scores_gemma":[0.00038781526,0.0003149438,0.00021317996,0.00055642804,0.00037240816,0.00023653744,0.0014360334,0.0022952422,0.0000045039596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031069116,0.00033679916,0.0000884963,0.0007368555,0.0000043315995,0.0000364735,0.0017953663,0.04819176,0.9464612,0.0002503285,0.000017499353,0.001770225],"study_design_scores_gemma":[0.001497124,0.0010247502,0.0060448963,0.00020841982,0.000008047637,0.0000050974313,0.00025605885,0.37293634,0.6151062,0.0023340483,0.00014392457,0.00043508288],"about_ca_topic_score_codex":0.00021092017,"about_ca_topic_score_gemma":0.00011089289,"teacher_disagreement_score":0.33135498,"about_ca_system_score_codex":0.00009716916,"about_ca_system_score_gemma":0.00025882336,"threshold_uncertainty_score":0.99993026},"labels":[],"label_agreement":null},{"id":"W4309474348","doi":"10.1017/s0963180122000056","title":"Biomarkers in Psychiatric Disorders","year":2022,"lang":"en","type":"article","venue":"Cambridge Quarterly of Healthcare Ethics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biomarker; Identification (biology); Psychiatry; Cognition; Medicine; Psychology; Biology","score_opus":0.03863808663375963,"score_gpt":0.3198998762280869,"score_spread":0.2812617895943273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309474348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94743145,0.0011443053,0.00012844901,0.046438497,0.0014832412,0.00068592007,0.00015060836,0.00012198704,0.0024155695],"genre_scores_gemma":[0.9968349,0.00013282009,0.000099871206,0.0026763869,0.000031253043,0.00007537754,0.000010655419,0.000033477787,0.00010525591],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9964449,0.0011663422,0.0005650291,0.0005739054,0.0007300898,0.0005197505],"domain_scores_gemma":[0.99840045,0.0007706013,0.00022213186,0.0004408889,0.000034398417,0.00013155384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094100676,0.00019409556,0.00027501766,0.0004782656,0.0004172019,0.000016879414,0.0005391718,0.00014322171,0.000046646026],"category_scores_gemma":[0.00023035343,0.00022244142,0.00013663685,0.0014257656,0.0002470952,0.00011507105,0.0000583171,0.0014993049,0.000014833729],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018956569,0.0034295325,0.03119809,0.0037642014,0.00006886428,0.00020739608,0.063478686,0.00036965127,0.028878354,0.39000666,0.02503111,0.45167178],"study_design_scores_gemma":[0.0323297,0.053940047,0.2872109,0.0005514932,0.00009397356,0.0008375645,0.24026762,0.007075031,0.0133137405,0.09461111,0.26099932,0.008769509],"about_ca_topic_score_codex":0.001480474,"about_ca_topic_score_gemma":0.000867684,"teacher_disagreement_score":0.44290227,"about_ca_system_score_codex":0.00012227173,"about_ca_system_score_gemma":0.0005144887,"threshold_uncertainty_score":0.90708977},"labels":[],"label_agreement":null},{"id":"W4309650147","doi":"10.1101/2022.11.20.22282570","title":"The interaction of polygenic risk for depression and age on white blood cell count","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Medical Research Council; Canadian Institutes of Health Research; Krembil Foundation","keywords":"Depression (economics); White blood cell; Polygenic risk score; Medicine; Longitudinal study; Epidemiology; Genome-wide association study; Biobank; Internal medicine; Demography; Biology; Bioinformatics; Genetics; Pathology; Genotype; Single-nucleotide polymorphism; Gene","score_opus":0.022874747825151694,"score_gpt":0.27246253003703297,"score_spread":0.24958778221188127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309650147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959938,0.0003806776,0.00009312387,0.00013844116,0.0009587676,0.00056804996,0.00011523999,0.00003582816,0.0017160826],"genre_scores_gemma":[0.99774235,0.00108192,0.000043884836,0.0001364923,0.000045427474,0.0001394804,0.0000070055908,0.000025326575,0.0007781332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986386,0.000212034,0.00023045474,0.00048489196,0.00025729105,0.0001767517],"domain_scores_gemma":[0.9984419,0.00071590056,0.00033318964,0.00045293564,0.000015707607,0.000040406572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029086394,0.00016576835,0.00017328162,0.000074576994,0.00029110204,0.00005859514,0.00037411487,0.000081293125,0.000054315304],"category_scores_gemma":[0.00039612444,0.00011820593,0.00011931218,0.000078089506,0.000088899986,0.00003104897,0.00041845458,0.00049997924,0.000002659655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023366758,0.0015729715,0.10797558,0.0011299838,0.00011175436,0.000050206752,0.0050935494,0.0037150225,0.84998775,0.00082754396,0.0038385808,0.023360377],"study_design_scores_gemma":[0.0025684505,0.0006562189,0.10464809,0.00019256437,0.00016712594,0.0000105755225,0.0008188751,0.0026820085,0.8422223,0.0049373833,0.040431764,0.0006646478],"about_ca_topic_score_codex":0.000023398785,"about_ca_topic_score_gemma":0.000023175908,"teacher_disagreement_score":0.036593184,"about_ca_system_score_codex":0.000018353061,"about_ca_system_score_gemma":0.000031165597,"threshold_uncertainty_score":0.48202977},"labels":[],"label_agreement":null},{"id":"W4310640214","doi":"10.1007/s00406-022-01519-0","title":"Importance of the dysregulation of the kynurenine pathway on cognition in schizophrenia: a systematic review of clinical studies","year":2022,"lang":"en","type":"review","venue":"European Archives of Psychiatry and Clinical Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Ministero della Salute; Macquarie University","keywords":"Schizophrenia (object-oriented programming); Kynurenine pathway; Cognition; Kynurenine; Psychology; Psychiatry; Systematic review; Disease; Clinical psychology; Medicine; MEDLINE; Internal medicine; Biology","score_opus":0.13476230020508065,"score_gpt":0.4030186511473137,"score_spread":0.2682563509422331,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310640214","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008228051,0.9846133,0.000004461088,0.0002928804,0.0022998361,0.0025621396,0.00017390671,0.0000141876035,0.0018112388],"genre_scores_gemma":[0.014470959,0.98457056,0.000058115198,0.00074633444,0.000051107923,0.000017328879,0.0000017347606,0.000026687776,0.00005717643],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9855639,0.008224887,0.0044954657,0.00082140195,0.0006925808,0.0002017886],"domain_scores_gemma":[0.9885281,0.005237987,0.0050265156,0.0011164362,0.000026665175,0.00006434026],"candidate_categories":["metaresearch","sts"],"consensus_categories":[],"category_scores_codex":[0.0030263653,0.00032474223,0.002441174,0.00012608188,0.00012991954,0.0000070942765,0.0016851723,0.000049548693,0.0000070842416],"category_scores_gemma":[0.017208606,0.00017442196,0.0012622307,0.0010622313,0.0028195425,0.00006391309,0.00072196266,0.00087394286,8.401802e-7],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019046881,0.0019256425,0.0013151126,0.9091104,0.000052300788,0.000005786155,0.000107965476,0.0000060659304,0.00011772341,0.0055954168,0.00008440752,0.08148867],"study_design_scores_gemma":[0.0016255864,0.0017037307,0.046666447,0.9415522,0.0009332263,0.000038199538,0.000094468,0.000049814265,0.00006191278,0.001721364,0.0050527225,0.0005002825],"about_ca_topic_score_codex":4.7421074e-7,"about_ca_topic_score_gemma":0.0000055149085,"teacher_disagreement_score":0.080988385,"about_ca_system_score_codex":0.0000040336045,"about_ca_system_score_gemma":0.00029138487,"threshold_uncertainty_score":0.9998942},"labels":[],"label_agreement":null},{"id":"W4311231483","doi":"10.1016/j.jad.2022.12.021","title":"Biomarkers of ketamine's antidepressant effect: An umbrella review","year":2022,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brain and Cognition Discovery Foundation; University Health Network","funders":"National Institute of Mental Health; National Institute on Aging","keywords":"Antidepressant; Ketamine; Medicine; Neuroimaging; Biomarker; Major depressive disorder; Neuroscience; Anterior cingulate cortex; Bioinformatics; Psychology; Psychiatry; Cognition; Biology; Anxiety","score_opus":0.04529618079029196,"score_gpt":0.35248722592264087,"score_spread":0.3071910451323489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311231483","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025710394,0.9941008,0.000031431206,0.000047296275,0.00087416155,0.0016557139,0.00007624486,0.000028802573,0.0029284647],"genre_scores_gemma":[0.0004573652,0.999018,0.00002551123,0.00019658021,0.0000776584,0.000054123884,0.00001485973,0.00012336293,0.00003249641],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99279106,0.0034624827,0.0015124896,0.0006866821,0.0010605889,0.00048667256],"domain_scores_gemma":[0.9928093,0.0030072206,0.0032117541,0.00065588293,0.000083637125,0.00023220462],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016462554,0.0007664572,0.0035036216,0.0008093683,0.00016417868,0.00003976134,0.0014339719,0.00021248963,0.0005882764],"category_scores_gemma":[0.0034632718,0.00057299243,0.0021200094,0.0018013386,0.0003732957,0.00036187636,0.00022370422,0.0011307177,0.0000130099115],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006061474,0.0004181363,0.000013415141,0.042488944,0.00027839368,0.00006650717,0.000041050294,0.0000042988863,0.00011942472,0.00005474244,0.0023028539,0.95415163],"study_design_scores_gemma":[0.0010858312,0.0023732164,0.00003885283,0.027376201,0.0012672787,0.00038387632,0.00005338941,0.00000413335,0.00022760856,0.00011679737,0.9664104,0.0006624016],"about_ca_topic_score_codex":0.000028346885,"about_ca_topic_score_gemma":0.000012656738,"teacher_disagreement_score":0.9641076,"about_ca_system_score_codex":0.00015876963,"about_ca_system_score_gemma":0.00043968682,"threshold_uncertainty_score":0.9996722},"labels":[],"label_agreement":null},{"id":"W4311449850","doi":"10.1139/cjc-2022-0256","title":"C–H arylation enables synthesis of imidazole-4-carboxamide (ICA) based fairy chemicals with plant growth-promoting activity","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Shoot; Plant growth; Agrochemical; Imidazole; Carboxamide; Derivatization; Elongation; Rice plant; Stereochemistry; Botany; Organic chemistry; Horticulture; High-performance liquid chromatography; Biology","score_opus":0.01403490542814004,"score_gpt":0.1920696997026924,"score_spread":0.17803479427455235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311449850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967793,0.000051571562,0.000039869916,0.0007029853,0.000047161484,0.0000577274,0.00011496764,0.000009039193,0.0021973846],"genre_scores_gemma":[0.9996855,0.0000030381418,0.000065880835,0.00014126617,0.00005195958,0.0000064909445,0.000002321508,0.000019132376,0.00002437213],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880236,0.000069362555,0.00028100173,0.00019295962,0.00036226955,0.00029204652],"domain_scores_gemma":[0.9986105,0.00038221542,0.00044283975,0.00016313717,0.00006276438,0.00033851812],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000251862,0.0001366233,0.00024205168,0.00010574439,0.00018885944,0.000029471019,0.00038954668,0.00005046255,0.00045747895],"category_scores_gemma":[0.0010278914,0.00013045382,0.0000964203,0.0002891963,0.00015427104,0.00012350304,0.000021919102,0.0003596073,4.5342586e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008116179,0.000040503088,0.0017165543,0.0001135925,0.000011900907,0.00014877597,0.00013342526,0.00030433212,0.99648446,0.0000075261405,0.00023749475,0.0007202814],"study_design_scores_gemma":[0.00031779087,0.000033797445,0.0008186891,0.00009876281,0.000014116819,0.00016517847,0.0002489956,0.0003645513,0.9974683,0.000063705396,0.00026421738,0.00014192032],"about_ca_topic_score_codex":0.00033460237,"about_ca_topic_score_gemma":0.00012067627,"teacher_disagreement_score":0.0029062454,"about_ca_system_score_codex":0.00018763822,"about_ca_system_score_gemma":0.0011405314,"threshold_uncertainty_score":0.5319752},"labels":[],"label_agreement":null},{"id":"W4311849805","doi":"10.3389/fncel.2022.999303","title":"Abnormal expression of cortical cell cycle regulators underlying anxiety and depressive-like behavior in mice exposed to chronic stress","year":2022,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Chronic stress; Cell cycle; Prefrontal cortex; Anxiety; Western blot; Biology; Kinase; Endocrinology; Internal medicine; Psychology; Cell; Neuroscience; Cell biology; Medicine; Cognition; Gene; Psychiatry; Genetics","score_opus":0.01948710437766138,"score_gpt":0.24212277585008407,"score_spread":0.2226356714724227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311849805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99560964,0.00027901723,0.0021689076,0.00004071903,0.0011050425,0.00061129994,0.000030263891,0.00003601128,0.000119115524],"genre_scores_gemma":[0.99894243,0.000051638017,0.0004796561,0.00029979207,0.000009998647,0.00009081024,0.0000018225832,0.000026776579,0.000097042335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99685293,0.00039065024,0.00043205413,0.0009900718,0.00071278546,0.0006214841],"domain_scores_gemma":[0.9991779,0.000090519105,0.00015159759,0.00037891034,0.000011593153,0.00018949014],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028536195,0.00022324156,0.00028334657,0.00040811463,0.000338125,0.000056566223,0.000853835,0.0000639699,0.000020745867],"category_scores_gemma":[0.00015559544,0.00024540085,0.000060210336,0.0011854556,0.00038261514,0.00030955605,0.000697344,0.0004843885,7.571507e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000063286796,0.00028721232,0.053258706,0.00003179441,1.3641613e-7,0.000096097974,0.0005024967,0.005718021,0.93910384,0.000019720268,0.00009290278,0.00082577416],"study_design_scores_gemma":[0.00093983294,0.00023149866,0.052677844,0.000027116583,0.0000039151987,0.000013801651,0.0006285451,0.009985022,0.9349377,0.000045263074,0.00023266599,0.0002767755],"about_ca_topic_score_codex":0.000024375398,"about_ca_topic_score_gemma":0.000011518023,"teacher_disagreement_score":0.0042670015,"about_ca_system_score_codex":0.00014969481,"about_ca_system_score_gemma":0.00011412184,"threshold_uncertainty_score":0.9999998},"labels":[],"label_agreement":null},{"id":"W4312086429","doi":"10.1002/alz.068991","title":"Peripheral blood leukotriene B4 and E4 as biomarkers in Alzheimer’s disease","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Sunnybrook Health Science Centre; Baycrest Hospital; Robarts Clinical Trials; Health Sciences Centre; Sunnybrook Hospital; University of Toronto","funders":"","keywords":"Stroop effect; Medicine; Dementia; Internal medicine; Psychology; Audiology; California Verbal Learning Test; Cognition; Trail Making Test; Hyperintensity; Verbal learning; Neuropsychology; Magnetic resonance imaging; Disease; Psychiatry","score_opus":0.02772571842317428,"score_gpt":0.2636870043251808,"score_spread":0.2359612859020065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312086429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.892471,0.1022501,0.0000061334163,0.0012251163,0.00046204976,0.00058755366,0.00004755441,0.00012932933,0.0028211512],"genre_scores_gemma":[0.9967817,0.00016231806,0.00009865918,0.002704289,0.00003129792,0.00014818608,0.000015492375,0.00003933128,0.000018697054],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99777126,0.0002540669,0.00029575516,0.0007239973,0.000439376,0.0005155643],"domain_scores_gemma":[0.9992209,0.00008488071,0.00009003478,0.00035208094,0.000010697931,0.00024142042],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019338717,0.0002469894,0.00018302115,0.00018169671,0.00041105953,0.00008830158,0.00039718475,0.000034484172,0.0015206123],"category_scores_gemma":[0.00006632644,0.00026955627,0.00008927389,0.000535616,0.00020136825,0.0002445007,0.00043766078,0.00020794579,0.000040406972],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004327455,0.008617809,0.1670147,0.000048868806,0.024684828,0.004562746,0.008629936,0.0010982904,0.29428312,0.04322913,0.038542047,0.40496108],"study_design_scores_gemma":[0.02551626,0.002128218,0.20893188,0.00006202769,0.02899627,0.00034618366,0.003911385,0.0044024196,0.39053208,0.015511995,0.31406686,0.0055944338],"about_ca_topic_score_codex":0.00016020078,"about_ca_topic_score_gemma":0.00003263701,"teacher_disagreement_score":0.39936665,"about_ca_system_score_codex":0.0000073557862,"about_ca_system_score_gemma":0.000111235786,"threshold_uncertainty_score":0.9999757},"labels":[],"label_agreement":null},{"id":"W4312086996","doi":"10.1002/alz.068024","title":"Exploring Inflammasome/Cytokine/Insulin cascade as converging landscape for AD, Schizophrenia(SCHIZO), and COVID‐19 syndrome: synthesis of evidence and Post‐hoc analysis of Ginsans‐115 RCT in treatment‐resistant‐schizophrenia","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nipissing University","funders":"","keywords":"Dementia; Schizophrenia (object-oriented programming); Medicine; Metabolic syndrome; Inflammasome; Randomized controlled trial; Internal medicine; Insulin resistance; Insulin; Psychiatry; Inflammation; Disease; Obesity","score_opus":0.10075089863706993,"score_gpt":0.2953093719889415,"score_spread":0.1945584733518716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312086996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9660545,0.032139767,0.000023832457,0.00043013177,0.00009329961,0.00072669727,0.00044374648,0.000054381257,0.000033669447],"genre_scores_gemma":[0.99583465,0.002834081,0.00060020847,0.0001572276,0.0000115486,0.0004838315,0.00002605566,0.00004508798,0.0000073083165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969488,0.00035125215,0.00078177924,0.00090971374,0.000512508,0.00049599214],"domain_scores_gemma":[0.99705166,0.0017541458,0.0004311823,0.00047961235,0.00005126436,0.0002321159],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050425925,0.00039648172,0.0008404999,0.001159715,0.00036480452,0.00006555199,0.0004114147,0.0000664497,0.00026548872],"category_scores_gemma":[0.00073997915,0.00037033076,0.00025153146,0.0016415408,0.00025962305,0.00058771094,0.00030219674,0.00016720354,0.0000023096143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.039484028,0.002338555,0.043692112,0.00078637834,0.042056408,0.00089832034,0.013782812,0.005902845,0.632796,0.0057376595,0.00017142798,0.21235345],"study_design_scores_gemma":[0.025092248,0.0067511555,0.2438176,0.00047357043,0.06570198,0.00032983086,0.009155772,0.014583355,0.62410843,0.000986632,0.0057598576,0.003239584],"about_ca_topic_score_codex":0.00045242786,"about_ca_topic_score_gemma":0.00042911086,"teacher_disagreement_score":0.20911387,"about_ca_system_score_codex":0.000034211807,"about_ca_system_score_gemma":0.000214614,"threshold_uncertainty_score":0.9998749},"labels":[],"label_agreement":null},{"id":"W4312104916","doi":"10.1093/geroni/igac059.1812","title":"DOES THE MICROBIOME INFLUENCE THE DEVELOPMENT OF DEMENTIA IN OLDER ADULTS?","year":2022,"lang":"en","type":"article","venue":"Innovation in Aging","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Dementia; Montreal Cognitive Assessment; Medicine; Gerontology; Logistic regression; Cognition; Clinical Dementia Rating; Comorbidity; Disease; Cognitive decline; Longitudinal study; Psychiatry; Internal medicine; Pathology","score_opus":0.013794987745471275,"score_gpt":0.2545720611527597,"score_spread":0.24077707340728843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312104916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977614,0.000017619566,0.000088144305,0.0016266357,0.00013191503,0.00020694366,0.0000017863165,0.000010960472,0.00015458578],"genre_scores_gemma":[0.9980239,0.0000012733174,0.000120030854,0.0017406093,0.0000044113813,0.00007092866,0.000001643977,0.000004552384,0.000032649907],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991101,0.00008346741,0.00036507501,0.00014845583,0.00016716335,0.00012576302],"domain_scores_gemma":[0.9996025,0.00011713916,0.00012794271,0.00012620502,0.000023048304,0.0000031600018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049557217,0.000053727672,0.000048437294,0.00022196241,0.00017472978,0.000018601637,0.00030896385,0.000008983312,0.000068984984],"category_scores_gemma":[0.00014060417,0.000029073864,0.000008014169,0.0023000757,0.00006191347,0.0000837307,0.00015669383,0.00015104403,0.0000022390013],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026444139,0.0001610783,0.08767974,0.00004646217,0.0000043751393,0.000003018302,0.051607657,0.0013751839,0.8291433,0.0068820715,0.00015455172,0.02291614],"study_design_scores_gemma":[0.000828514,0.0000071875747,0.59581476,0.00007288224,8.6610675e-7,0.0000023086623,0.008966154,0.0002343905,0.387274,0.00089041574,0.0057696537,0.0001388433],"about_ca_topic_score_codex":0.000023131088,"about_ca_topic_score_gemma":0.000060231763,"teacher_disagreement_score":0.508135,"about_ca_system_score_codex":0.00003895381,"about_ca_system_score_gemma":0.000053047894,"threshold_uncertainty_score":0.13438979},"labels":[],"label_agreement":null},{"id":"W4312116946","doi":"10.1016/j.jpsychires.2022.12.047","title":"Childhood trauma, inflammatory biomarkers and the presence of a current depressive episode: Is there a relationship in subjects from a population study?","year":2022,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Medicine; Population; Confounding; Logistic regression; Major depressive disorder; Depression (economics); Internal medicine; Cytokine; Cross-sectional study; Population study; Anxiety; Immunology; Psychiatry; Amygdala","score_opus":0.058035242685989676,"score_gpt":0.3562721339884534,"score_spread":0.2982368913024637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312116946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99159235,0.006061429,0.000011026567,0.0011842942,0.00023208695,0.0007562564,0.000013226281,0.000003968499,0.00014533687],"genre_scores_gemma":[0.99960005,0.00022063382,0.00003351076,0.000023241055,0.00006326373,0.000035880486,4.7243176e-7,0.0000112690905,0.000011683251],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9945586,0.0029769014,0.00060752174,0.00025084062,0.0013716164,0.00023455574],"domain_scores_gemma":[0.99662215,0.002522073,0.00044859867,0.00025597477,0.00008090815,0.000070320246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0026810768,0.00009789737,0.00021857036,0.00072585896,0.00037492468,0.000051643685,0.0005745999,0.000031963024,0.00006665628],"category_scores_gemma":[0.0017727901,0.00006812112,0.00009918656,0.0015833215,0.00018706702,0.00017257086,0.0001895379,0.0010564232,0.0000011520069],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011603765,0.0007400342,0.97910357,0.00002601389,0.00002484998,0.000019211022,0.010236618,0.00015567982,0.00023114508,0.0006704839,0.00078921573,0.0068428298],"study_design_scores_gemma":[0.004566266,0.00029193974,0.97351944,0.0000308596,0.00001151453,0.00001573961,0.004055035,0.0002776559,0.00012934276,0.016981501,0.000053307733,0.0000674125],"about_ca_topic_score_codex":0.0003887689,"about_ca_topic_score_gemma":0.00013063669,"teacher_disagreement_score":0.016311016,"about_ca_system_score_codex":0.000060026196,"about_ca_system_score_gemma":0.00015598943,"threshold_uncertainty_score":0.45896915},"labels":[],"label_agreement":null},{"id":"W4312127301","doi":"10.3390/biomedicines10123213","title":"A Scoping Review of Rodent Studies Investigating the Epigenetic Mechanisms in the Brain Underlying the Effects of Diet on Depressive-like Behaviour","year":2022,"lang":"en","type":"review","venue":"Biomedicines","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Epigenome; Epigenetics; Mood; DNA methylation; Anxiety; Psychology; Major depressive disorder; Systematic review; Clinical psychology; Bioinformatics; Biology; MEDLINE; Psychiatry; Genetics","score_opus":0.17237110674215472,"score_gpt":0.4110687117184744,"score_spread":0.2386976049763197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312127301","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00033253196,0.9937911,0.000008952822,0.0012250486,0.00062004814,0.003957186,0.000010141965,0.000016154276,0.000038804028],"genre_scores_gemma":[0.001599776,0.9932816,0.000010529364,0.0040795086,0.000038006558,0.0009366125,0.0000056488793,0.00003218081,0.00001614033],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9952576,0.0022573106,0.0009011132,0.0004627792,0.000835337,0.00028586178],"domain_scores_gemma":[0.9862106,0.011991807,0.0010024271,0.0007405043,0.00002327474,0.000031380165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015830011,0.0003738504,0.0013421526,0.0001813741,0.0002933199,0.000016621694,0.0013008227,0.000057471956,0.000015618105],"category_scores_gemma":[0.007360652,0.00015287902,0.00029811103,0.0013650127,0.0006752161,0.000027685657,0.0003301194,0.0004313058,0.0000014470735],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006425954,0.00015848978,0.0000074025925,0.5965334,0.0000903866,0.000052167197,0.0036746967,0.0000019591016,0.0010174884,0.0008427088,0.00097099313,0.39664388],"study_design_scores_gemma":[0.0003730631,0.00078443054,0.00008401922,0.9820594,0.0005779,0.00003583838,0.0019337287,0.0000028546267,0.00041716633,0.00063677883,0.012794828,0.00029998805],"about_ca_topic_score_codex":0.00004113956,"about_ca_topic_score_gemma":0.000024330428,"teacher_disagreement_score":0.3963439,"about_ca_system_score_codex":0.000043502663,"about_ca_system_score_gemma":0.0001814053,"threshold_uncertainty_score":0.881192},"labels":[],"label_agreement":null},{"id":"W4312128763","doi":"10.3233/jad-220906","title":"Tryptophan Metabolism and Neurodegeneration: Longitudinal Associations of Kynurenine Pathway Metabolites with Cognitive Performance and Plasma Alzheimer’s Disease and Related Dementias Biomarkers in the Duke Physical Performance Across the LifeSpan Study","year":2022,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Aging; National Institutes of Health","keywords":"Kynurenine; Neurodegeneration; Kynurenine pathway; Internal medicine; Montreal Cognitive Assessment; Dementia; Biomarker; Cognitive decline; Kynurenic acid; Endocrinology; Medicine; Alzheimer's disease; Psychology; Gerontology; Disease; Tryptophan; Biology; Biochemistry; Glutamate receptor","score_opus":0.034759914149685704,"score_gpt":0.2811372174824322,"score_spread":0.2463773033327465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312128763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99099416,0.007228156,0.0000013234712,0.00084084686,0.000104649436,0.00063200196,0.0001722787,0.000008779454,0.000017819677],"genre_scores_gemma":[0.9993109,0.00028565095,0.000008955607,0.00023839448,0.00006563473,0.00005940027,0.0000067184183,0.000019547335,0.0000048061743],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.997491,0.0006878341,0.00046095334,0.00033957898,0.0007428119,0.000277839],"domain_scores_gemma":[0.9986034,0.00037083472,0.00051119877,0.00018928746,0.00010350083,0.00022176944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063259585,0.0002414246,0.00033124557,0.00012956023,0.0007943089,0.0001266828,0.0002623562,0.000018468663,0.000013925092],"category_scores_gemma":[0.0002003649,0.00014600519,0.00008467917,0.00059654174,0.00043994066,0.0005457304,0.00016887975,0.00038707265,3.4361037e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006283587,0.0046130847,0.94078517,0.00005804187,0.0027675403,0.00036034267,0.026154581,0.00121604,0.0043600574,0.00064879487,0.00014504755,0.012607714],"study_design_scores_gemma":[0.0033652761,0.00053449307,0.98517686,0.000021751825,0.0017181266,0.00005613401,0.0028730645,0.003789481,0.0022030284,0.000039865026,0.00003714016,0.00018476167],"about_ca_topic_score_codex":0.000007079736,"about_ca_topic_score_gemma":0.000008326019,"teacher_disagreement_score":0.04439171,"about_ca_system_score_codex":0.000007884856,"about_ca_system_score_gemma":0.00014961282,"threshold_uncertainty_score":0.6109262},"labels":[],"label_agreement":null},{"id":"W4312186750","doi":"10.3390/ijms24010133","title":"NLRP3 Inflammasome: From Pathophysiology to Therapeutic Target in Major Depressive Disorder","year":2022,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; University of British Columbia","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo; University of Victoria","keywords":"Inflammasome; Proinflammatory cytokine; Neuroinflammation; Pyrin domain; Antidepressant; Major depressive disorder; Medicine; Inflammation; Neuroscience; Immunology; Biology; Hippocampus; Amygdala","score_opus":0.0352057114221181,"score_gpt":0.332727572551631,"score_spread":0.2975218611295129,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312186750","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008746688,0.98690957,0.00058581197,0.00073002797,0.0020842294,0.00040903306,0.00007535291,0.000011330653,0.00044797137],"genre_scores_gemma":[0.0067400383,0.9899788,0.00065423077,0.0022901653,0.00020135198,0.00006166207,0.000008415279,0.000030431365,0.000034902925],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99645823,0.00064802764,0.0008374613,0.0005125868,0.0012528787,0.00029078533],"domain_scores_gemma":[0.998115,0.000691885,0.00084351114,0.00018221683,0.000066806744,0.00010057424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043371113,0.00028064125,0.000724373,0.00089402305,0.000100831254,0.00014515044,0.002920095,0.00009810026,0.0006202355],"category_scores_gemma":[0.0008656888,0.00021372715,0.00042327595,0.0007674245,0.00022873533,0.00022409362,0.00044064265,0.00053496764,0.000031880194],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048617734,0.00019428332,0.000041935655,0.00007271611,0.00009289535,0.0016774405,0.00030726485,0.0009707823,0.005704255,0.001079275,0.00010112519,0.98970944],"study_design_scores_gemma":[0.0007326235,0.0002941884,0.00008017063,0.0011158442,0.00004957893,0.00018775894,0.00017101497,0.000045717727,0.0012051403,0.014861744,0.9807831,0.00047313765],"about_ca_topic_score_codex":0.00003077627,"about_ca_topic_score_gemma":0.000009372152,"teacher_disagreement_score":0.9892363,"about_ca_system_score_codex":0.00012625159,"about_ca_system_score_gemma":0.00054351386,"threshold_uncertainty_score":0.8715541},"labels":[],"label_agreement":null},{"id":"W4312264912","doi":"10.2139/ssrn.4254422","title":"Minocycline Treatment Improves Cognitive and Functional Plasticity in a Preclinical Mouse Model of Major Depressive Disorder","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; University of Victoria","funders":"","keywords":"Minocycline; Major depressive disorder; Neuroplasticity; Cognition; Neuroscience; Depression (economics); Preclinical research; Psychology; Clinical psychology; Medicine; Psychiatry; Biology","score_opus":0.028138777211213432,"score_gpt":0.2800918551884653,"score_spread":0.25195307797725186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312264912","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951726,0.0005578681,0.0036053942,0.00023091784,0.000047591227,0.00022836434,0.000071600654,0.000012196625,0.00007346351],"genre_scores_gemma":[0.9980223,0.0008510192,0.000024392559,0.00012536229,0.000031391693,0.00004936876,0.0000035962496,0.000015646325,0.0008769002],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9980593,0.00017896178,0.00032284754,0.00032079307,0.00026732945,0.00085077126],"domain_scores_gemma":[0.9992183,0.0004500631,0.00018043898,0.000062802894,0.000024074596,0.00006432372],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022148289,0.00014786981,0.00021374662,0.00013265313,0.0002370545,0.00001588822,0.000116052324,0.00003922051,0.000044607194],"category_scores_gemma":[0.00037482413,0.00012695162,0.00008874546,0.00014043321,0.00013564533,0.00011811285,0.00009610243,0.0009198626,0.0000012155846],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010508386,0.0076722526,0.026280157,0.0000380583,0.00036491922,0.00003057156,0.0021795752,0.027181474,0.81958956,0.036224987,0.0000409354,0.06988912],"study_design_scores_gemma":[0.074998245,0.016005615,0.03109604,0.00007255613,0.0003872738,0.0013244052,0.017054724,0.2129972,0.2464292,0.39756465,0.00018456917,0.0018855241],"about_ca_topic_score_codex":0.000047898677,"about_ca_topic_score_gemma":0.00070995267,"teacher_disagreement_score":0.57316035,"about_ca_system_score_codex":0.00023057914,"about_ca_system_score_gemma":0.00090291497,"threshold_uncertainty_score":0.5176937},"labels":[],"label_agreement":null},{"id":"W4313331446","doi":"10.1186/s12974-022-02649-x","title":"Correction: Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression","year":2022,"lang":"en","type":"erratum","venue":"Journal of Neuroinflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Fluoxetine; Mechanism (biology); Inhibitory postsynaptic potential; Phosphorylation; Depression (economics); Neuroscience; Neurology; Pharmacology; Chemistry; Cell biology; Psychology; Medicine; Biology; Biochemistry; Receptor; Serotonin; Philosophy","score_opus":0.026685250095215763,"score_gpt":0.25558005489849844,"score_spread":0.22889480480328267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313331446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98357403,0.000040965082,0.0005715563,0.00019637393,0.014328896,0.00039444465,0.000013474649,0.00005223992,0.00082799135],"genre_scores_gemma":[0.99253744,0.00020756938,0.000111170426,0.000048575726,0.0006128303,0.000012603102,0.000025507754,0.000090553745,0.0063537345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961696,0.00064591126,0.001173658,0.00050574023,0.0012183506,0.0002866894],"domain_scores_gemma":[0.99631035,0.00023183635,0.0026436355,0.00045778416,0.00021899602,0.00013737472],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005829088,0.00038202706,0.00062637223,0.00090594176,0.00020702145,0.00007193146,0.0005106024,0.00037279827,0.0001450572],"category_scores_gemma":[0.0008530434,0.00038569453,0.00025378616,0.00053239544,0.00005589654,0.0012838776,0.00014892123,0.0018502062,0.0000036988913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046906428,0.00027946936,0.000017043894,0.00008828846,0.0000058569876,0.000033275424,0.00032980117,0.018193617,0.96570134,0.000034940273,0.009708846,0.005138485],"study_design_scores_gemma":[0.00085635856,0.00044975532,0.0011757719,0.00015997342,0.000023331215,0.0000770445,0.00003912977,0.18172081,0.8139344,0.00104625,0.00023471074,0.00028248123],"about_ca_topic_score_codex":0.000015539536,"about_ca_topic_score_gemma":0.00004653201,"teacher_disagreement_score":0.16352719,"about_ca_system_score_codex":0.0002536818,"about_ca_system_score_gemma":0.0004236184,"threshold_uncertainty_score":0.9998595},"labels":[],"label_agreement":null},{"id":"W4313381148","doi":"10.4049/jimmunol.202.supp.137.1","title":"Fatty acid depletion is a reversible cause of kynurenine induced T cell apoptosis","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Kynurenine; Catabolism; Metabolite; Chemistry; T cell; Apoptosis; Metabolism; Biochemistry; Biology; Tryptophan; Immune system; Immunology; Amino acid","score_opus":0.024413248321568545,"score_gpt":0.24746490227872675,"score_spread":0.2230516539571582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313381148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969936,0.00028135497,0.000070166614,0.0012441995,0.00043177063,0.000097868935,0.0000028150348,0.0000072075,0.0008710438],"genre_scores_gemma":[0.99864525,0.00047636914,0.00007541218,0.00056725694,0.000022362132,4.386548e-7,1.8985828e-7,0.000009674384,0.00020305502],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989913,0.00024720814,0.00031790358,0.00009173493,0.00017213039,0.00017968491],"domain_scores_gemma":[0.9989649,0.00019094949,0.00048305775,0.00026537658,0.000072039424,0.000023680112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027133687,0.0000946071,0.00022556543,0.00014102679,0.00005178604,0.000006764886,0.00047345177,0.00008667848,0.00034775262],"category_scores_gemma":[0.00014403643,0.00006261642,0.00009670524,0.00025673042,0.00010865937,0.00013035195,0.00007637529,0.00032606316,0.00009203889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030596822,0.00007640681,0.00030882124,0.000009547667,0.000022248045,0.0000014088811,0.00083846727,0.0000075607313,0.99733907,0.000096362026,0.000589651,0.0004045104],"study_design_scores_gemma":[0.0011014569,0.00060611573,0.0034091128,0.000020881555,0.00002309515,0.00009261083,0.00051866774,0.000008549597,0.9935659,0.00021612336,0.00037369918,0.000063748856],"about_ca_topic_score_codex":0.00001848067,"about_ca_topic_score_gemma":0.0000015133915,"teacher_disagreement_score":0.0037731095,"about_ca_system_score_codex":0.000024912513,"about_ca_system_score_gemma":0.00005689891,"threshold_uncertainty_score":0.38076472},"labels":[],"label_agreement":null},{"id":"W4313403229","doi":"10.5152/pcp.2022.22447","title":"A Comparison of the Relationship Between C-Reactive Protein Levels and Cognitive Functions in Patients with Schizophrenia, First-Episode Psychosis, and Healthy Controls","year":2023,"lang":"en","type":"article","venue":"Psychiatry and Clinical Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Psychosis; Cognition; Neuropsychology; Psychology; C-reactive protein; Clinical psychology; Psychiatry; Medicine; Inflammation; Internal medicine","score_opus":0.0767621629235213,"score_gpt":0.40503793587587894,"score_spread":0.32827577295235766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313403229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910158,0.00017151117,0.000036155063,0.0064504617,0.0006082965,0.0014168866,0.00012982643,0.00003961166,0.00013148414],"genre_scores_gemma":[0.9985078,0.000009638472,0.00004601736,0.0011760424,0.000087391876,0.000114638984,0.000005245503,0.000017220136,0.00003601247],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99766636,0.0005965895,0.00065221626,0.0006141309,0.00017217475,0.00029854284],"domain_scores_gemma":[0.9958986,0.0034234845,0.00033133174,0.00015040158,0.000037550504,0.00015861374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036826349,0.0001945596,0.00043975108,0.0001395515,0.0003208011,0.000018953226,0.0001364456,0.0001868212,0.000017116281],"category_scores_gemma":[0.0006405744,0.00014366333,0.000060858656,0.0006484086,0.00078641914,0.00012188153,0.000066568944,0.00069554604,0.000009065952],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037288154,0.0006434094,0.99331236,0.000050631737,0.00003642129,2.356124e-7,0.000109102395,0.0000011518242,0.000030203199,0.00054386887,0.00032099203,0.0012228073],"study_design_scores_gemma":[0.015222334,0.0010948404,0.97940207,0.00010256642,0.00006677653,6.922832e-7,0.00016747501,0.000036043886,0.000023001812,0.0036341227,0.00009548487,0.00015458766],"about_ca_topic_score_codex":0.00002145375,"about_ca_topic_score_gemma":0.0003407255,"teacher_disagreement_score":0.013910286,"about_ca_system_score_codex":0.000007845813,"about_ca_system_score_gemma":0.00003693352,"threshold_uncertainty_score":0.5858421},"labels":[],"label_agreement":null},{"id":"W4313446155","doi":"10.1007/978-3-031-14023-5_10","title":"Combating the Sustained Inflammation Involved in Aging and Neurodegenerative Diseases with Probiotics","year":2023,"lang":"en","type":"book-chapter","venue":"Healthy ageing and longevity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Neuroprotection; Neurodegeneration; Gut–brain axis; Irritable bowel syndrome; Inflammation; Disease; Medicine; Parkinson's disease; Immune system; Microbiome; Immunology; Neuroscience; Biology; Bioinformatics; Internal medicine","score_opus":0.03292304104214407,"score_gpt":0.2579913114880544,"score_spread":0.2250682704459103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313446155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97914714,0.0011553057,0.000111092275,0.010148657,0.00021241128,0.0021899168,0.000060191935,0.00033283123,0.0066424496],"genre_scores_gemma":[0.99174964,0.0012149367,0.000037534108,0.0011347795,0.00011443311,0.000019970978,0.000017077618,0.000056779812,0.005654843],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.99861664,0.00017334195,0.00025378456,0.00048255958,0.00020006663,0.000273624],"domain_scores_gemma":[0.9988155,0.0006654602,0.00020160798,0.00019029168,0.000029177596,0.000097958684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026499637,0.00024631785,0.00028003153,0.00012505517,0.00043025854,0.00012273478,0.00009388974,0.00009899574,0.000002532884],"category_scores_gemma":[0.00033448616,0.00017378417,0.000024978222,0.000106868545,0.00026574035,0.00011244751,0.00010840336,0.0004897976,0.000002122056],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022768704,0.00028983882,0.024447445,0.014972109,0.000120533245,0.003478954,0.041076932,0.0018445085,0.004171779,0.6809763,0.0009861047,0.22535864],"study_design_scores_gemma":[0.029274698,0.009069328,0.5485587,0.020844247,0.00080532406,0.00031440196,0.020345343,0.0944796,0.009530959,0.22313102,0.030625075,0.013021319],"about_ca_topic_score_codex":0.000043828783,"about_ca_topic_score_gemma":0.0011269947,"teacher_disagreement_score":0.5241113,"about_ca_system_score_codex":0.000037657654,"about_ca_system_score_gemma":0.00009754468,"threshold_uncertainty_score":0.7086713},"labels":[],"label_agreement":null},{"id":"W4313644357","doi":"10.3389/fmolb.2022.1067296","title":"Nicotinamide as potential biomarker for Alzheimer’s disease: A translational study based on metabolomics","year":2023,"lang":"en","type":"article","venue":"Frontiers in Molecular Biosciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; International Society for Neurochemistry; Universität zu Köln; Agencia Nacional de Promoción Científica y Tecnológica; McGill University; Consejo Nacional de Investigaciones Científicas y Técnicas; Rheinische Friedrich-Wilhelms-Universität Bonn; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft; Consortium canadien en neurodégénérescence associée au vieillissement","keywords":"Metabolomics; Nicotinamide adenine dinucleotide; NAD+ kinase; Metabolome; Dementia; Internal medicine; Biomarker; Alzheimer's disease; Endocrinology; Chemistry; Nicotinamide; Hippocampus; Amyloid (mycology); Disease; Biochemistry; Biology; Medicine; Pathology; Chromatography; Enzyme","score_opus":0.027539519381281165,"score_gpt":0.29365212568013593,"score_spread":0.26611260629885475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313644357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9349009,0.00039321624,0.055820864,0.0036319767,0.002368629,0.0020952327,0.00014322091,0.00021803966,0.0004279606],"genre_scores_gemma":[0.9956742,0.00001433498,0.0028151753,0.0012346385,0.000017730481,0.00013628873,0.00001593339,0.000021354586,0.00007037015],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9975835,0.00020706854,0.00024910347,0.00079744926,0.00069277076,0.00047012436],"domain_scores_gemma":[0.9993965,0.00010689739,0.00007054136,0.00026703003,0.000021308724,0.00013772039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045689396,0.0002033141,0.00019356358,0.00060433574,0.00023719235,0.00010861761,0.0005869797,0.000052601703,0.000016579941],"category_scores_gemma":[0.00050206285,0.00018453627,0.00016054566,0.0016184951,0.00034053624,0.00013349352,0.000038209066,0.00008791177,0.000018275914],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044053006,0.0061229304,0.08520168,0.00009986291,0.00015432648,0.0012046528,0.0016031602,0.084483795,0.71129894,0.009668235,0.020725356,0.07503175],"study_design_scores_gemma":[0.005703031,0.0008439047,0.16603306,0.00004159172,0.00012397028,0.0000026078062,0.0019985915,0.7066713,0.09568324,0.017872611,0.003916568,0.0011095467],"about_ca_topic_score_codex":0.00000853667,"about_ca_topic_score_gemma":0.000004486504,"teacher_disagreement_score":0.6221875,"about_ca_system_score_codex":0.000015813293,"about_ca_system_score_gemma":0.00018309885,"threshold_uncertainty_score":0.75251704},"labels":[],"label_agreement":null},{"id":"W4313909178","doi":"10.1016/j.schres.2022.12.049","title":"Depression trajectories and cytokines in schizophrenia spectrum disorders - A longitudinal observational study","year":2023,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Helse Vest Regionalt Helseføretak; Norges Forskningsråd; Helse Vest","keywords":"Positive and Negative Syndrome Scale; Psychology; Schizophrenia (object-oriented programming); Depression (economics); Observational study; Cytokine; Clinical psychology; Major depressive disorder; Internal medicine; Psychiatry; Latent growth modeling; Medicine; Psychosis; Cognition; Developmental psychology","score_opus":0.16326030151564475,"score_gpt":0.38567371560977765,"score_spread":0.2224134140941329,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313909178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957623,0.00014269911,0.000006476185,0.0021440524,0.00021697849,0.0009779449,0.000024318144,0.00024860966,0.00047663474],"genre_scores_gemma":[0.9988413,0.00021070949,0.00009268639,0.000029856335,0.00016356706,0.0002226647,0.000011177492,0.00004695124,0.0003811309],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9954649,0.00068373076,0.0004168943,0.0011003133,0.0013702345,0.00096391235],"domain_scores_gemma":[0.99800277,0.001242816,0.000057838934,0.0004641476,0.000042489293,0.00018994138],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013654114,0.00027636602,0.00029700852,0.0011704533,0.00066573976,0.0002631013,0.0005927431,0.00011148748,0.00011698752],"category_scores_gemma":[0.0018433616,0.0002478441,0.00006290846,0.0041425033,0.0004942523,0.00045993752,0.000547601,0.0008280118,0.00019556661],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0059585366,0.0012414822,0.90453506,0.00011195957,0.000024632525,0.00033250713,0.002280914,0.00017899372,0.048225056,0.015870431,0.0015705987,0.019669812],"study_design_scores_gemma":[0.004007001,0.00027933982,0.9618015,0.000043570126,0.0000026312732,0.000008342927,0.00081589434,0.0007903386,0.0042805383,0.027438981,0.00024806228,0.0002837786],"about_ca_topic_score_codex":0.00037801248,"about_ca_topic_score_gemma":0.0040427884,"teacher_disagreement_score":0.057266444,"about_ca_system_score_codex":0.0000652559,"about_ca_system_score_gemma":0.00021379777,"threshold_uncertainty_score":0.9999974},"labels":[],"label_agreement":null},{"id":"W4315621764","doi":"10.1038/s41398-022-02305-1","title":"Serum complement proteins rather than inflammatory factors is effective in predicting psychosis in individuals at clinical high risk","year":2023,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Science and Technology Commission of Shanghai Municipality; Shanghai Clinical Research Center; National Natural Science Foundation of China","keywords":"Inflammation; Psychosis; Tumor necrosis factor alpha; Complement factor I; Medicine; Complement (music); Immunology; Internal medicine; Cytokine; Schizophrenia (object-oriented programming); Complement factor B; Complement system; Biology; Antibody; Psychiatry; Gene; Phenotype","score_opus":0.03750571122186718,"score_gpt":0.32530691517302457,"score_spread":0.2878012039511574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315621764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940276,0.00004018145,0.00003698649,0.0026013863,0.00076618517,0.0015212002,0.00046440493,0.00015469467,0.0003873723],"genre_scores_gemma":[0.9988199,0.000037284128,0.00023893334,0.00048577748,0.00012793296,0.00016080709,0.000034419983,0.000036972004,0.0000580015],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99707127,0.00055485667,0.0007253581,0.0006737902,0.00053792854,0.00043677344],"domain_scores_gemma":[0.99873215,0.0007361345,0.00018921292,0.00023265216,0.000013394256,0.00009644881],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007628139,0.00024676617,0.0002769832,0.00036299494,0.0001777383,0.000028933411,0.00027132436,0.00016402046,0.00033594752],"category_scores_gemma":[0.000104915365,0.00023423634,0.00016663143,0.00090067607,0.00012176109,0.00018664685,0.00004311051,0.00047953567,0.00015971965],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007541395,0.00023782719,0.99455976,0.00003321273,0.00001883917,0.000001473347,0.002046158,0.00032362793,0.00029411283,0.000771893,0.00053277967,0.0011049028],"study_design_scores_gemma":[0.0030611297,0.000102561826,0.98573655,0.00007999134,0.000007399291,5.3264256e-7,0.00023451204,0.00053836615,0.00076538464,0.008761812,0.00047472015,0.00023706055],"about_ca_topic_score_codex":0.000113847156,"about_ca_topic_score_gemma":0.0021746294,"teacher_disagreement_score":0.008823229,"about_ca_system_score_codex":0.000042562846,"about_ca_system_score_gemma":0.0000771775,"threshold_uncertainty_score":0.9551881},"labels":[],"label_agreement":null},{"id":"W4315643894","doi":"10.1016/j.bbr.2023.114295","title":"Minocycline treatment improves cognitive and functional plasticity in a preclinical mouse model of major depressive disorder","year":2023,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; University of Victoria","funders":"Ministero della Salute; Consejo Nacional de Ciencia y Tecnología; Government of Canada","keywords":"Minocycline; Anhedonia; Major depressive disorder; Neuroscience; Psychology; Cognition; Neuroplasticity; Long-term potentiation; Hippocampus; Hippocampal formation; Effects of sleep deprivation on cognitive performance; Antidepressant; Microglia; Medicine; Internal medicine; Inflammation; Antibiotics; Biology","score_opus":0.23848130917991625,"score_gpt":0.41790779779401216,"score_spread":0.1794264886140959,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315643894","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99758464,0.00003649477,0.00007235718,0.0011011014,0.000028914172,0.00071933604,0.00030669456,0.000053336244,0.000097132484],"genre_scores_gemma":[0.9961368,0.00007467603,0.00004210546,0.00007536791,0.000019208734,0.00022314613,0.000027703225,0.000022521981,0.0033784795],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99757063,0.00035919287,0.00033477697,0.0006146873,0.0005786158,0.00054208667],"domain_scores_gemma":[0.9955118,0.004042281,0.00005844689,0.0001465537,0.00009241239,0.00014851126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034186384,0.00016583901,0.00024698654,0.00038722018,0.00016693969,0.000039450384,0.00015439405,0.000121393656,0.000051141607],"category_scores_gemma":[0.0035842832,0.00013660506,0.000075561045,0.0005905116,0.00066717865,0.00014388448,0.00024436408,0.00034744444,0.000028714774],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013620201,0.0013192744,0.08653376,0.000043834243,0.000015032005,0.000048534283,0.00087997643,0.00029967702,0.89627916,0.00041415627,0.00044681333,0.01235777],"study_design_scores_gemma":[0.008553129,0.0010297569,0.58460367,0.00006501031,0.000016254688,0.000006062045,0.0010304947,0.047832504,0.35497186,0.0015534218,0.000015945428,0.00032190164],"about_ca_topic_score_codex":0.00038419152,"about_ca_topic_score_gemma":0.0006233942,"teacher_disagreement_score":0.5413073,"about_ca_system_score_codex":0.00003920918,"about_ca_system_score_gemma":0.00013733564,"threshold_uncertainty_score":0.5570592},"labels":[],"label_agreement":null},{"id":"W4315796630","doi":"10.3389/fphar.2023.1134918","title":"Editorial: Anti-inflammatory immunopharmacology in the prevention and treatment of major chronic diseases","year":2023,"lang":"en","type":"editorial","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Immunopharmacology; Medicine; Inflammation; Pharmacology; Human physiology; Clinical pharmacology; Immunology; Internal medicine; Immune system","score_opus":0.011163005515931728,"score_gpt":0.302227163475825,"score_spread":0.29106415795989327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315796630","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.029344201,0.004156239,0.0000064206843,0.00019653163,0.96472365,0.001244488,0.00022257245,0.0000647523,0.00004115177],"genre_scores_gemma":[0.011572076,0.024378333,0.000017302691,0.00006049784,0.9626937,0.00075594545,0.000105591644,0.00007864076,0.00033791846],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.996256,0.0012268279,0.0006519785,0.0007668203,0.00047017133,0.0006282137],"domain_scores_gemma":[0.99726987,0.0019901788,0.0003726912,0.00025894647,0.00003840292,0.00006989582],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036371604,0.00042182577,0.00080952246,0.00062791014,0.00009333207,0.000026545486,0.00067460106,0.0006766,0.000055690976],"category_scores_gemma":[0.00041487598,0.0003485532,0.00016156951,0.0005494783,0.00059038354,0.00013116654,0.00012417434,0.00063253177,0.000013606026],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043438937,0.00051422766,0.00028113113,0.00016871814,0.0000657082,0.00012277532,0.00037592227,0.000035335637,0.021110108,0.000008605338,0.9744568,0.0024262962],"study_design_scores_gemma":[0.0077942037,0.00074359693,0.0005815152,0.000048145954,0.00017091617,0.0000013986919,0.00015814228,0.00009978886,0.005864839,0.0004805534,0.9837297,0.0003271539],"about_ca_topic_score_codex":0.000050357587,"about_ca_topic_score_gemma":0.00005485626,"teacher_disagreement_score":0.020222096,"about_ca_system_score_codex":0.00049722317,"about_ca_system_score_gemma":0.0006905599,"threshold_uncertainty_score":0.99989665},"labels":[],"label_agreement":null},{"id":"W4315928425","doi":"10.1093/ibd/izac262","title":"Sustained Diet-Induced Remission in Pediatric Crohn’s Disease Is Associated With Kynurenine and Serotonin Pathways","year":2023,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Azrieli Foundation; Department of Pediatrics, School of Medicine, University of Virginia; Amsterdam University Medical Centers; Children's Health Research Institute; Women and Children's Health Research Institute; Nestlé Health Science","keywords":"Kynurenine pathway; Quinolinic acid; Kynurenine; Internal medicine; Gastroenterology; Tryptophan; Calprotectin; Serotonin; Medicine; Crohn's disease; Feces; Endocrinology; Disease; Inflammatory bowel disease; Chemistry; Biology; Biochemistry","score_opus":0.01860757415259064,"score_gpt":0.23934586978751524,"score_spread":0.2207382956349246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315928425","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975644,0.00015511892,0.0000010118163,0.000540861,0.00008504712,0.0006896137,0.00015012285,0.00057924795,0.0002345731],"genre_scores_gemma":[0.99852175,0.00019345949,0.0000023807952,0.00058321276,0.00007366084,0.0001536873,0.00003737642,0.000057091675,0.00037739493],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99761665,0.00019890403,0.00033237872,0.0007166404,0.0005206593,0.0006147864],"domain_scores_gemma":[0.9985297,0.00033861693,0.00015437351,0.00036188174,0.00006233683,0.0005531122],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013672259,0.00033026427,0.00024930848,0.0003827899,0.00024317276,0.00011262157,0.0002585224,0.00009858783,0.00006867259],"category_scores_gemma":[0.002024632,0.00028346473,0.000072890325,0.0011876051,0.00012790291,0.0003556585,0.00020973176,0.00019479315,0.000048614722],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037007194,0.0006783255,0.9529001,0.00062002,0.000023521814,0.013111675,0.0016016843,0.00016619616,0.016672697,0.0006736636,0.008117713,0.0017336808],"study_design_scores_gemma":[0.0020473874,0.00008804632,0.9936785,0.00010293446,0.000030781805,0.0000012493718,0.00024846246,0.0009027051,0.0013957157,0.0009895134,0.00010446732,0.00041022638],"about_ca_topic_score_codex":0.000005578376,"about_ca_topic_score_gemma":0.000018037439,"teacher_disagreement_score":0.040778406,"about_ca_system_score_codex":0.00007887869,"about_ca_system_score_gemma":0.00034493883,"threshold_uncertainty_score":0.99996173},"labels":[],"label_agreement":null},{"id":"W4317380799","doi":"10.1016/j.nbd.2023.106005","title":"Neuro-immune crosstalk in depressive symptoms of multiple sclerosis","year":2023,"lang":"en","type":"review","venue":"Neurobiology of Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Multiple sclerosis; Antidepressant; Immune system; Depression (economics); Context (archaeology); Psychiatry; Psychology; Medicine; Major depressive disorder; Depressive symptoms; Crosstalk; Neuroscience; Clinical psychology; Cognition; Immunology; Anxiety; Biology","score_opus":0.08445001255986236,"score_gpt":0.31038188723035876,"score_spread":0.2259318746704964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317380799","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09516926,0.9001893,0.0000017227246,0.00003849532,0.0008087754,0.0017092942,0.0018042929,0.00016238891,0.00011649672],"genre_scores_gemma":[0.056305647,0.9431252,0.0000029355656,0.00013378999,0.000027336362,0.00014464639,0.000069472444,0.00009702272,0.00009395502],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965829,0.0007424473,0.001074661,0.0009413584,0.0001717257,0.00048689396],"domain_scores_gemma":[0.99588126,0.0023424106,0.00079702714,0.0007850151,0.000032549757,0.00016176711],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009492401,0.00047575188,0.0017129148,0.0005019471,0.000057471058,0.000012915236,0.0009797057,0.0002625802,0.00004219692],"category_scores_gemma":[0.0030423258,0.0004167094,0.0007317868,0.0009185421,0.00085995777,0.00007553366,0.00043104455,0.00042667828,0.00007064791],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012107149,0.0045498377,0.005177325,0.1002849,0.00031106605,0.00039066735,0.00030130617,0.00030872232,0.04644407,0.001181136,0.0012844783,0.83855575],"study_design_scores_gemma":[0.027245479,0.0051962677,0.1805334,0.1198746,0.004259336,0.00005774324,0.000111370195,0.00025833515,0.05229214,0.002586482,0.5971763,0.0104085365],"about_ca_topic_score_codex":0.000022188915,"about_ca_topic_score_gemma":0.000008575115,"teacher_disagreement_score":0.82814723,"about_ca_system_score_codex":0.000019122914,"about_ca_system_score_gemma":0.00025479138,"threshold_uncertainty_score":0.99982846},"labels":[],"label_agreement":null},{"id":"W4317547578","doi":"10.3389/fpsyt.2022.1070456","title":"Imaging oxidative stress in brains of chronic methamphetamine users: A combined 1H-magnetic resonance spectroscopy and peripheral blood biomarker study","year":2023,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Defence Research and Development Canada; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; National Institutes of Health","keywords":"Oxidative stress; Biomarker; Magnetic resonance imaging; Peripheral blood; Medicine; Peripheral; Nuclear magnetic resonance; Internal medicine; Radiology; Chemistry; Biochemistry; Physics","score_opus":0.011206157989725102,"score_gpt":0.26592619369250636,"score_spread":0.25472003570278123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317547578","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99036676,0.0056285476,0.00013651667,0.00062089576,0.0020952728,0.000756673,0.000040653926,0.000079527475,0.00027517127],"genre_scores_gemma":[0.99711543,0.00039950904,0.001973895,0.00016192607,0.000039357237,0.0000576861,0.000004864159,0.00003890961,0.00020844016],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99775505,0.00032074546,0.0004287341,0.0007110317,0.00026135423,0.0005230691],"domain_scores_gemma":[0.99932116,0.000097954035,0.0001214232,0.00037426656,0.000014324995,0.00007085584],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002872367,0.00026137565,0.00040443745,0.0005568881,0.00007198235,0.00004187407,0.00036648285,0.00006220822,0.000036437872],"category_scores_gemma":[0.00016047123,0.0002684015,0.000059703638,0.001692067,0.00033236112,0.00021260281,0.00012959458,0.00026124023,0.0000024117471],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027156447,0.0015203331,0.9519283,0.0000865899,0.000016695192,0.000047894446,0.0027305768,0.000029599381,0.03356192,0.00015531469,0.0040958025,0.0055554006],"study_design_scores_gemma":[0.011599959,0.0011179089,0.9530353,0.00025890116,0.000025724374,0.0000054683996,0.012527393,0.008435362,0.009186553,0.0031452423,0.00015361614,0.00050859933],"about_ca_topic_score_codex":0.00008142754,"about_ca_topic_score_gemma":0.00062720245,"teacher_disagreement_score":0.024375366,"about_ca_system_score_codex":0.000067407025,"about_ca_system_score_gemma":0.00011988384,"threshold_uncertainty_score":0.9999768},"labels":[],"label_agreement":null},{"id":"W4318481956","doi":"10.21203/rs.3.rs-1647827/v1","title":"Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Icahn School of Medicine at Mount Sinai; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Immune system; Matrix metalloproteinase; Peripheral; Immunology; Matrix (chemical analysis); Medicine; Chemistry; Internal medicine","score_opus":0.11238541825915759,"score_gpt":0.4050346784556048,"score_spread":0.2926492601964472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318481956","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899366,0.00067958067,0.0000597671,0.002087319,0.0005161816,0.0041801147,0.00066536915,0.00089009356,0.0009849751],"genre_scores_gemma":[0.9907517,0.00035439018,0.00030436277,0.000026014432,0.0002422686,0.0008966421,0.00013084513,0.00016117592,0.0071326448],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9909799,0.0023135287,0.0006354018,0.0021392496,0.0023513553,0.0015805837],"domain_scores_gemma":[0.99599475,0.00090582983,0.0001758377,0.0021444154,0.00040926257,0.00036988722],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0021344493,0.0005618898,0.000676309,0.0005701616,0.00066287327,0.00070498855,0.0020110814,0.00054737285,0.0010771843],"category_scores_gemma":[0.0065094433,0.0005148588,0.00053050875,0.0011038315,0.0009794751,0.0001998399,0.0040692613,0.0031194515,0.0008368785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003642652,0.0010388255,0.0016308507,0.0052154665,0.00006881033,0.00063452724,0.0021726643,0.00055574946,0.98278326,0.0013189192,0.0013782978,0.0028383955],"study_design_scores_gemma":[0.0013692238,0.0006363425,0.02491109,0.0012808803,0.00001642078,0.000009730845,0.002850528,0.0023030771,0.93952024,0.024324259,0.0014522776,0.0013259372],"about_ca_topic_score_codex":0.0011197287,"about_ca_topic_score_gemma":0.0004657525,"teacher_disagreement_score":0.043263,"about_ca_system_score_codex":0.0003585021,"about_ca_system_score_gemma":0.00073332555,"threshold_uncertainty_score":0.9999411},"labels":[],"label_agreement":null},{"id":"W4318537696","doi":"10.4103/ejpsy.ejpsy_44_21","title":"CRP and its relation to cognitive performance in schizophrenia patients: a cross-sectional study","year":2022,"lang":"en","type":"article","venue":"Egyptian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Positive and Negative Syndrome Scale; Cognition; Schizophrenia (object-oriented programming); Internal medicine; Montreal Cognitive Assessment; Cross-sectional study; Psychopathology; Correlation; Psychology; C-reactive protein; Etiology; Medicine; Psychosis; Clinical psychology; Psychiatry; Cognitive impairment; Inflammation; Pathology","score_opus":0.018623678041395704,"score_gpt":0.27983411645107487,"score_spread":0.26121043840967917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318537696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976313,0.00011666551,0.000015214539,0.00021778201,0.0013976924,0.00028947138,0.000015876369,0.00000860353,0.0003074054],"genre_scores_gemma":[0.99918824,0.000007244261,0.00011353519,0.00050298806,0.00011152956,0.000011156976,8.5564335e-7,0.000012726857,0.000051709772],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985226,0.00018426879,0.00043208816,0.00022550742,0.00047082474,0.00016471019],"domain_scores_gemma":[0.9994699,0.00006441699,0.0002366794,0.00006248193,0.00006862631,0.00009792262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036321444,0.00010460868,0.00012580508,0.0003549085,0.00029793513,0.000054782853,0.00018056289,0.00002470558,0.00019006697],"category_scores_gemma":[0.00021754703,0.00010363284,0.00004598648,0.00049052463,0.000027453993,0.0003521451,0.00008110734,0.00045784118,0.000015497013],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011790168,0.00069959264,0.99541265,0.000009496714,0.0000067884685,0.0000071874056,0.0010052607,0.00038731183,0.00023761179,0.0001804793,0.000075261196,0.000799373],"study_design_scores_gemma":[0.0042772237,0.0017267343,0.9924731,0.000025595305,0.000004060562,0.000048404272,0.00080806087,0.000080395475,0.00008267013,0.00029524436,0.00006430145,0.000114190254],"about_ca_topic_score_codex":0.0000013217724,"about_ca_topic_score_gemma":0.00001128193,"teacher_disagreement_score":0.003098207,"about_ca_system_score_codex":0.0000516379,"about_ca_system_score_gemma":0.000111905705,"threshold_uncertainty_score":0.42260247},"labels":[],"label_agreement":null},{"id":"W4318946535","doi":"10.1016/j.jad.2023.01.094","title":"Diet and depression: A systematic review of whole dietary interventions as treatment in patients with depression","year":2023,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta","keywords":"Depression (economics); Psychological intervention; Psychiatry; Medicine; Psychology; MEDLINE; Clinical psychology; Biology","score_opus":0.03697661873549773,"score_gpt":0.34153304726839895,"score_spread":0.3045564285329012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318946535","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018350582,0.99489146,0.000010287599,0.00001787794,0.0001451652,0.002937084,0.000043705077,0.000012603258,0.00010673714],"genre_scores_gemma":[0.0024927692,0.9971735,0.000012259259,0.00003626159,0.000012881515,0.000162238,0.000010949347,0.000050450108,0.000048709997],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9968465,0.0009387036,0.0011673054,0.0003660737,0.0004634798,0.00021792376],"domain_scores_gemma":[0.99670655,0.00093138276,0.001880364,0.00028703178,0.000092769485,0.000101914855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033332274,0.00041105034,0.0024695075,0.00050772435,0.000064305495,0.00002407717,0.00029302313,0.00011552848,0.000012766414],"category_scores_gemma":[0.0018284345,0.000233173,0.00078237447,0.0007681592,0.00011400419,0.00021321926,0.00009787461,0.0003191454,0.000009321142],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010689178,0.000885884,0.00063654385,0.88720137,0.00023164325,0.000025971818,0.0001416352,0.0000021622077,8.7962303e-7,0.0000032949529,0.000088709334,0.11067504],"study_design_scores_gemma":[0.0015461454,0.002060017,0.0014969035,0.9922238,0.0012445151,0.000019767323,0.00013786106,0.0000011523359,0.000004899044,0.000070639326,0.0009409366,0.0002533431],"about_ca_topic_score_codex":0.000025919451,"about_ca_topic_score_gemma":0.0000938197,"teacher_disagreement_score":0.11042169,"about_ca_system_score_codex":0.00012845555,"about_ca_system_score_gemma":0.0001380987,"threshold_uncertainty_score":0.9508519},"labels":[],"label_agreement":null},{"id":"W4319786785","doi":"10.3390/brainsci13020292","title":"The Role of Tryptophan Metabolism in Alzheimer’s Disease","year":2023,"lang":"en","type":"review","venue":"Brain Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto Western Hospital","funders":"Krembil Foundation","keywords":"Druggability; Neurotoxicity; Quinolinic acid; Microglia; Alzheimer's disease; Metabolite; Biochemistry; Biology; Neurodegeneration; Xanthurenic acid; Neurotoxin; Tryptophan; Pharmacology; Disease; Inflammation; Medicine; Amino acid; Immunology; Gene; Internal medicine; Toxicity","score_opus":0.11489010532666007,"score_gpt":0.3712361382208274,"score_spread":0.25634603289416735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319786785","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000066251894,0.995411,5.7213833e-7,0.00036270107,0.00043978984,0.00070561835,0.000057189773,0.00007102612,0.002885898],"genre_scores_gemma":[0.00035814216,0.9988874,0.000015158752,0.00016761315,0.000084981264,0.00013444027,0.0000021799665,0.00003113425,0.0003189117],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965212,0.00063092477,0.00068132987,0.00079892133,0.00077985326,0.0005878028],"domain_scores_gemma":[0.99549115,0.0034530004,0.00039979728,0.00049100805,0.000015179553,0.00014986505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012180917,0.00033284482,0.0008218791,0.0004069065,0.00038588408,0.00016968633,0.002212236,0.00010252874,0.000028030769],"category_scores_gemma":[0.0030827655,0.00019389964,0.00040113376,0.0031805933,0.0015967652,0.00018115115,0.00029416222,0.00025326447,0.00016256291],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000038050177,0.00003796,0.0000025070076,0.00029483222,0.000008624774,0.000010160299,0.000089057416,0.000002741128,0.000028814085,0.031856894,0.00046224557,0.96720237],"study_design_scores_gemma":[0.00008652024,0.000015350124,0.000054710123,0.0010300637,0.000046123772,0.0000026754913,0.00015664058,0.00003979716,0.000117798016,0.010877565,0.9873254,0.0002473781],"about_ca_topic_score_codex":0.000035004803,"about_ca_topic_score_gemma":0.000048485777,"teacher_disagreement_score":0.98686314,"about_ca_system_score_codex":0.000014711308,"about_ca_system_score_gemma":0.00068638206,"threshold_uncertainty_score":0.7906998},"labels":[],"label_agreement":null},{"id":"W4319875484","doi":"10.1139/bcb-2022-0349","title":"Maternal use of methamphetamine alters cardiovascular function in the adult offspring","year":2023,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute","keywords":"Methamphetamine; Offspring; Pregnancy; Medicine; Physiology; Bioinformatics; Internal medicine; Biology; Genetics","score_opus":0.05986444350582443,"score_gpt":0.27726062835033094,"score_spread":0.2173961848445065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319875484","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.028537923,0.9705105,0.000016473203,0.000007848469,0.00018202885,0.00025684727,0.000060989845,0.00002466962,0.0004027147],"genre_scores_gemma":[0.015416802,0.9842054,0.000010332251,0.0000603207,0.000065254164,0.000036966605,0.000031249845,0.000013145015,0.00016051724],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986911,0.00025603245,0.00031514507,0.00044608075,0.00009013213,0.00020150562],"domain_scores_gemma":[0.999159,0.00030984712,0.00014921401,0.00034327718,0.000010983172,0.00002770933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002004737,0.00021549712,0.0006177113,0.0000613456,0.000033675988,0.000018194154,0.00025799646,0.00026792075,0.0000068910463],"category_scores_gemma":[0.00016788056,0.00014051615,0.00033041002,0.0002462784,0.00017282895,0.00002132036,0.00006720968,0.00021038395,0.000007640238],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002979481,0.00007368989,0.000042049534,0.019664157,0.00014239122,0.000040843424,0.000053662545,0.0000040091686,0.07883782,0.00014689549,0.00009939384,0.9008653],"study_design_scores_gemma":[0.00040940606,0.00007038029,0.000051466057,0.0013807828,0.00028493587,0.000057520156,0.00007569306,0.000008043492,0.1213816,0.000050942952,0.8758393,0.00038994904],"about_ca_topic_score_codex":0.00005907987,"about_ca_topic_score_gemma":0.0000016993594,"teacher_disagreement_score":0.9004753,"about_ca_system_score_codex":0.0000123825275,"about_ca_system_score_gemma":0.00003616782,"threshold_uncertainty_score":0.57300824},"labels":[],"label_agreement":null},{"id":"W4320033674","doi":"10.1016/j.bbi.2023.02.007","title":"Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells","year":2023,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Menzies Centre for Australian Studies, King's College London, University of London; Medical Research Council; Medical Research Council Centre for Neurodevelopmental Disorders; National Centre for the Replacement, Refinement and Reduction of Animals in Research; King's College London; Canadian Celiac Association; Wellcome Trust","keywords":"Biology; Microglia; Wnt signaling pathway; Progenitor cell; Neural stem cell; Cell biology; Signal transduction; Immunology; Stem cell; Inflammation","score_opus":0.03876467112189081,"score_gpt":0.2862321341453605,"score_spread":0.24746746302346967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320033674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980619,0.00005490766,0.0000014461555,0.00048243898,0.00034820754,0.0006057853,0.00015336832,0.00020952772,0.00008239581],"genre_scores_gemma":[0.9978136,0.000058893933,0.000046360954,0.00081142184,0.000049774095,0.000104857536,0.00002191079,0.000040834777,0.0010523533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977097,0.0004356226,0.00039884206,0.00051264407,0.00029292068,0.0006502885],"domain_scores_gemma":[0.99882805,0.00049435056,0.0000875883,0.00038750714,0.000026896649,0.00017559719],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038108937,0.0002849208,0.00031529233,0.00023918139,0.00033719366,0.00013379428,0.00045000148,0.00018177129,0.000068482244],"category_scores_gemma":[0.00022273164,0.00027775104,0.00013797802,0.00072509696,0.0003013606,0.00023187259,0.00022120298,0.00063031353,0.000060566592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000115036775,0.00019645937,0.002050395,0.000017004095,0.0000040647,0.000206367,0.0006841856,0.0000058685873,0.9888569,0.000016777982,0.00042306905,0.007423847],"study_design_scores_gemma":[0.001744688,0.00020945667,0.05556133,0.000020445503,0.00002579418,0.000043428267,0.0008571475,0.00010270314,0.9402544,0.000020854211,0.0007755096,0.0003842442],"about_ca_topic_score_codex":0.00026704805,"about_ca_topic_score_gemma":0.00005226294,"teacher_disagreement_score":0.053510934,"about_ca_system_score_codex":0.000047934092,"about_ca_system_score_gemma":0.000102488375,"threshold_uncertainty_score":0.99996746},"labels":[],"label_agreement":null},{"id":"W4320483711","doi":"10.1038/s41598-023-29101-1","title":"Identification of novel targets and pathways to distinguish suicide dependent or independent on depression diagnosis","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Shanghai University of Traditional Chinese Medicine; National Natural Science Foundation of China; Shanghai Municipal Health Commission","keywords":"Identification (biology); Depression (economics); Computational biology; Suicide prevention; Human factors and ergonomics; Poison control; Injury prevention; Medicine; Bioinformatics; Biology; Medical emergency; Ecology","score_opus":0.05389870748939462,"score_gpt":0.29927611386885883,"score_spread":0.2453774063794642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320483711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99486357,0.000026099235,0.00030075308,0.00014471359,0.0035390984,0.0005780426,0.000031563613,0.00016001688,0.00035614113],"genre_scores_gemma":[0.99810225,0.000013947019,0.00005741159,0.00010268268,0.000032264183,0.00011192656,0.000015842494,0.000021854185,0.001541795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967296,0.000055505134,0.0006428476,0.0012091084,0.0009957204,0.00036720026],"domain_scores_gemma":[0.99830663,0.00026203986,0.00038422443,0.00076052686,0.00009213893,0.00019441682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011990455,0.00016905753,0.00019567383,0.00041990148,0.00037827794,0.0002535255,0.00024045468,0.00006822201,0.00005375347],"category_scores_gemma":[0.0051165656,0.00013619433,0.000061018698,0.0011424989,0.00016988948,0.00015272794,0.00026191265,0.000103446524,0.000052727035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038054415,0.00025350065,0.010149889,0.00004221836,0.0000029479504,0.0002848649,0.0007623395,0.00037394997,0.9771264,0.00014634914,0.0040649725,0.006754471],"study_design_scores_gemma":[0.00022650299,0.000050330258,0.046662536,0.00008726379,0.000005579984,0.000054769203,0.00019463895,0.00032453437,0.9496926,0.0011935085,0.001323709,0.0001840189],"about_ca_topic_score_codex":0.00002662254,"about_ca_topic_score_gemma":0.00006628133,"teacher_disagreement_score":0.036512647,"about_ca_system_score_codex":0.000036595735,"about_ca_system_score_gemma":0.000076698336,"threshold_uncertainty_score":0.6125377},"labels":[],"label_agreement":null},{"id":"W4321016266","doi":"10.1159/000528770","title":"Changes in Inflammatory Markers in Clinical High Risk of Developing Psychosis","year":2023,"lang":"en","type":"article","venue":"Neuropsychobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Psychosis; Internal medicine; Analysis of variance; Medicine; Tumor necrosis factor alpha; Interleukin; Schizophrenia (object-oriented programming); Vascular endothelial growth factor; Gastroenterology; Clinical significance; Cytokine; Psychology; Oncology; Psychiatry; VEGF receptors","score_opus":0.04344782523922,"score_gpt":0.325620834363014,"score_spread":0.28217300912379395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321016266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964644,0.000012973209,0.000006131609,0.0012396466,0.0012545735,0.0002350904,0.00001392943,0.000092389884,0.0006808722],"genre_scores_gemma":[0.99652004,0.0017195285,0.000061071565,0.0015358141,0.000048606882,0.000033358952,0.000003030856,0.000022232274,0.00005630401],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.997378,0.0009627841,0.0005632135,0.00058911915,0.00009571135,0.00041120718],"domain_scores_gemma":[0.9983384,0.0011056538,0.00019038437,0.00030588981,0.000012987975,0.00004665743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006243808,0.00015118821,0.00030465453,0.00050839694,0.00002947586,0.000006919248,0.000373608,0.00017289376,0.000048],"category_scores_gemma":[0.0013523821,0.0001440209,0.000064058004,0.0011894142,0.00026749718,0.0000442478,0.0000911827,0.00037869616,0.00014257502],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034970167,0.000122023936,0.9026932,0.000037700007,0.000006460791,0.000080842074,0.00019831072,0.000043155986,0.06081625,0.0016721882,0.0016929017,0.03228725],"study_design_scores_gemma":[0.0012206543,0.0001656467,0.9901034,0.000031344378,0.0000014659279,0.000003704783,0.00004948995,0.00006242615,0.003350231,0.0012346564,0.0036328293,0.00014414109],"about_ca_topic_score_codex":0.000052000203,"about_ca_topic_score_gemma":0.0012040314,"teacher_disagreement_score":0.0874102,"about_ca_system_score_codex":0.000015113506,"about_ca_system_score_gemma":0.000032071937,"threshold_uncertainty_score":0.58730024},"labels":[],"label_agreement":null},{"id":"W4321081786","doi":"10.21203/rs.3.rs-2549830/v1","title":"Factors associated with the prevalence of depression among people with oculocutaneous albinism in Jinja,Uganda.A cross sectional study","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Oculocutaneous albinism; Depression (economics); Cross-sectional study; Marital status; Demography; Logistic regression; Albinism; Checklist; Medicine; Psychology; Population; Psychiatry; Environmental health; Internal medicine","score_opus":0.10582742837701416,"score_gpt":0.3844363754706052,"score_spread":0.2786089470935911,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321081786","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99635166,0.000042583542,0.000011976088,0.00007310157,0.000112018424,0.0027711554,0.00029438495,0.0001292155,0.00021390662],"genre_scores_gemma":[0.9974473,0.000039248647,0.0000017339811,0.0000070122614,0.000029614468,0.00035232626,0.000023879591,0.00007334297,0.0020255062],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9929427,0.0016208484,0.0003999118,0.0012299404,0.0030329435,0.0007736943],"domain_scores_gemma":[0.9950872,0.0032551633,0.00027726186,0.00086673885,0.000381407,0.00013222158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016637733,0.00036009323,0.0004145412,0.0004551851,0.0004873526,0.00028182482,0.0012556873,0.00028521716,0.00010060611],"category_scores_gemma":[0.0026802397,0.00020682927,0.000104368286,0.0015553222,0.00078515074,0.00013759716,0.0011833998,0.0022014875,0.000009099453],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023275566,0.000608412,0.988858,0.0005304779,0.000034136538,0.00010549998,0.004402224,0.0046125497,0.0005134897,0.000008077148,0.000067416746,0.000026998156],"study_design_scores_gemma":[0.00085168093,0.00065624324,0.9919596,0.0006442763,0.0000088589595,0.000002853203,0.0022322135,0.0003825986,0.0028901594,0.000118540076,0.000004263336,0.00024876956],"about_ca_topic_score_codex":0.0011255165,"about_ca_topic_score_gemma":0.009007108,"teacher_disagreement_score":0.007881592,"about_ca_system_score_codex":0.0002133328,"about_ca_system_score_gemma":0.0004670179,"threshold_uncertainty_score":0.95644903},"labels":[],"label_agreement":null},{"id":"W4321370231","doi":"10.1001/jamanetworkopen.2023.0147","title":"Effect of Adjunctive Simvastatin on Depressive Symptoms Among Adults With Treatment-Resistant Depression","year":2023,"lang":"en","type":"article","venue":"JAMA Network Open","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Grand Challenges Canada; University of Toronto; King's College London; Department of Psychiatry, University of Toronto; Fondation Brain Canada; Centre for Addiction and Mental Health Foundation; Wellcome Trust; National Institute for Health and Care Research; Medical Research Council; Sanofi","keywords":"Tolerability; Medicine; Clinical Global Impression; Placebo; Adjunctive treatment; Internal medicine; Major depressive disorder; Depression (economics); Randomized controlled trial; Hamilton Anxiety Rating Scale; Anxiety; Antidepressant; Clinical trial; Psychiatry; Adverse effect","score_opus":0.011310863426316509,"score_gpt":0.2676677639473675,"score_spread":0.25635690052105103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321370231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896381,0.00004317669,0.000012173303,0.00006585063,0.0001237344,0.0017397038,0.00004732937,0.00012152411,0.008208394],"genre_scores_gemma":[0.99865127,0.00003625734,0.000021494563,0.00015068648,0.00008599945,0.00032078213,0.000031152318,0.000045964745,0.0006563682],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99765086,0.0006310867,0.00023197316,0.00066645385,0.00034888065,0.00047076662],"domain_scores_gemma":[0.9970825,0.002059819,0.00025482886,0.00045158836,0.000028977129,0.00012231627],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025110104,0.00029129558,0.00039804104,0.00008378691,0.00021902488,0.00012829433,0.0005657135,0.00009348732,0.00006392926],"category_scores_gemma":[0.00029719016,0.00018036742,0.0000841681,0.0008303765,0.00015917771,0.00029642435,0.00024827453,0.00014496947,0.00006629365],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.09140887,0.0009459793,0.27093297,0.00030628205,0.00038091955,0.0011989499,0.004422991,0.09339748,0.021484379,0.000881127,0.02112194,0.49351808],"study_design_scores_gemma":[0.021490179,0.012870609,0.52898264,0.0027567511,0.000090592555,0.0000051995744,0.00024471906,0.008760761,0.42307383,0.00021890353,0.0007749783,0.0007308613],"about_ca_topic_score_codex":0.00018761153,"about_ca_topic_score_gemma":0.00012982577,"teacher_disagreement_score":0.49278724,"about_ca_system_score_codex":0.00004772715,"about_ca_system_score_gemma":0.000039731836,"threshold_uncertainty_score":0.73551697},"labels":[],"label_agreement":null},{"id":"W4321486004","doi":"10.2174/1570159x21666230222092029","title":"The Gut-Brain Axis and the Microbiome in Anxiety Disorders,Post-Traumatic Stress Disorder and Obsessive-Compulsive Disorder","year":2023,"lang":"en","type":"article","venue":"Current Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"University of Alberta","keywords":"Anxiety; Obsessive compulsive; Microbiome; Gut microbiome; Acute Stress Disorder; Psychology; Psychiatry; Neuroscience; Generalized anxiety disorder; Clinical psychology; Anxiety disorder; Medicine; Bioinformatics; Biology","score_opus":0.017136538557787157,"score_gpt":0.2961864859511174,"score_spread":0.2790499473933302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321486004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97450894,0.003767023,0.000017830318,0.018511841,0.0015487111,0.0013265328,0.00008925843,0.00013908737,0.00009078419],"genre_scores_gemma":[0.9785966,0.019199265,0.0000027018539,0.0016469107,0.00006579425,0.00024035633,0.000015131362,0.000049926926,0.00018328108],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99644864,0.0012169254,0.00046392492,0.00083680614,0.00022783832,0.0008058923],"domain_scores_gemma":[0.9951777,0.004136805,0.00018184545,0.00034222272,0.00003429749,0.00012711524],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000338305,0.00039499227,0.00037554337,0.00022132545,0.00077703025,0.00016549262,0.00067252695,0.00008043964,0.00005385526],"category_scores_gemma":[0.0009725571,0.00024663683,0.0001088339,0.0011255214,0.0020464219,0.00018675243,0.00062880554,0.00065217126,0.00006363936],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002081427,0.0018552669,0.048296478,0.0008795616,0.000111354675,0.00012960064,0.022558708,0.0007730136,0.23918103,0.011468352,0.014092874,0.6585723],"study_design_scores_gemma":[0.039503172,0.0007209832,0.5724548,0.00018060266,0.0001386541,0.00015333357,0.011921826,0.0285334,0.0039890246,0.005753334,0.33438972,0.0022611208],"about_ca_topic_score_codex":0.000056730936,"about_ca_topic_score_gemma":0.00036049687,"teacher_disagreement_score":0.6563112,"about_ca_system_score_codex":0.00001868167,"about_ca_system_score_gemma":0.000048642585,"threshold_uncertainty_score":0.99999857},"labels":[],"label_agreement":null},{"id":"W4321605720","doi":"10.1101/2023.02.18.23286124","title":"Microglial function moderates the relation between depression risk factors and depression outcomes across the life course in females","year":2023,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Medical Research Council; National Medical Research Council; Hope for Depression Research Foundation; National Research Foundation Singapore; National University Health System; National Research Foundation","keywords":"Depression (economics); Offspring; Longitudinal study; Biobank; Medicine; Stressor; Internal medicine; Demography; Psychology; Pregnancy; Psychiatry; Bioinformatics; Biology; Pathology","score_opus":0.07137104988372521,"score_gpt":0.3221041747571596,"score_spread":0.25073312487343435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321605720","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99589247,0.00056429254,0.00040578103,0.0009651701,0.0011076097,0.00071424304,0.00014555118,0.00017854129,0.00002637448],"genre_scores_gemma":[0.9990027,0.0003612827,0.0000110197625,0.0001508696,0.00016150481,0.00007618527,0.000027044063,0.000051160077,0.00015821552],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99720573,0.0007193511,0.000430814,0.0008245386,0.00043293214,0.0003866042],"domain_scores_gemma":[0.99682826,0.0020479106,0.0003797512,0.00062653824,0.000030485,0.00008707181],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072137685,0.00037647254,0.00035384388,0.0000812345,0.0007618919,0.00027780858,0.00053706596,0.0003681116,0.000008731782],"category_scores_gemma":[0.0022868724,0.00019126142,0.00014119328,0.00021909298,0.00029195668,0.00015828238,0.0008614314,0.00096030475,0.000023717028],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043632972,0.000030287838,0.99081635,0.000022893348,0.000021127908,0.0000027731624,0.0019095641,0.0021954328,0.0036262749,0.000009509964,0.00006549162,0.0012566741],"study_design_scores_gemma":[0.0003635016,0.000011789596,0.98268104,0.00007896481,0.0000534158,6.095097e-7,0.0006837055,0.0019462751,0.011864505,0.0020453958,0.00005140967,0.00021937754],"about_ca_topic_score_codex":0.00044297343,"about_ca_topic_score_gemma":0.00042959067,"teacher_disagreement_score":0.00823823,"about_ca_system_score_codex":0.00002181057,"about_ca_system_score_gemma":0.00005535481,"threshold_uncertainty_score":0.7799415},"labels":[],"label_agreement":null},{"id":"W4323351044","doi":"10.1093/jcag/gwac036.008","title":"A8 MICROBIAL ACTIVATION OF INTESTINAL DENDRITIC CELLS IS CRITICAL FOR THE ESTABLISHMENT OF NORMAL BEHAVIOR","year":2023,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Centre for Addiction and Mental Health; McMaster University","funders":"","keywords":"Biology; Immune system; CD11c; Lipopolysaccharide; Colonization; Gut–brain axis; Gut flora; Immunofluorescence; Immunology; Microbiology; Phenotype; Gene; Antibody","score_opus":0.019116403990740483,"score_gpt":0.25964516067467563,"score_spread":0.24052875668393514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323351044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9827841,0.0000018859582,0.00015746061,0.016076548,0.00062823674,0.0001800452,0.00014160211,0.0000022343033,0.000027867107],"genre_scores_gemma":[0.9985314,0.0000052579794,0.0001278126,0.0011532082,0.0000595196,0.000003694979,9.832208e-7,0.0000074972127,0.00011065382],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986707,0.00019518546,0.00051196537,0.00008280261,0.0002695629,0.00026978223],"domain_scores_gemma":[0.99792314,0.00079602236,0.0007943466,0.00010668713,0.00030503309,0.000074768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000625095,0.0000712614,0.00020439204,0.00020356239,0.000093288436,0.000014147997,0.00037771201,0.000065254695,0.000040893723],"category_scores_gemma":[0.0022295394,0.000052655534,0.00018952122,0.00018160485,0.00015779452,0.000096851065,0.000032844637,0.00017944437,0.0000011634907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049835455,0.00022513217,0.17014101,0.00007737694,0.00006990119,0.0000053299327,0.00076181244,0.00037065157,0.7808998,0.00055537117,0.046015415,0.00037983007],"study_design_scores_gemma":[0.002688378,0.0015588182,0.42945424,0.000118525124,0.00018043883,0.00006461629,0.0006030567,0.00041268987,0.5630027,0.00037393323,0.0014522264,0.00009038971],"about_ca_topic_score_codex":0.0007154147,"about_ca_topic_score_gemma":0.0123231225,"teacher_disagreement_score":0.2593132,"about_ca_system_score_codex":0.00025245853,"about_ca_system_score_gemma":0.00025823334,"threshold_uncertainty_score":0.68765914},"labels":[],"label_agreement":null},{"id":"W4324085226","doi":"10.1101/2023.03.11.532237","title":"Antibody targeting of aging damaged isoDGR-proteins doubles lifespan in a mouse model of chronic inflammation","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"","keywords":"Inflammation; Immune system; Antibody; Cytokine; Immunotherapy; Immunology; Immunosenescence; Monoclonal antibody; Biology; Chemistry","score_opus":0.0287054499583603,"score_gpt":0.2549066558648597,"score_spread":0.22620120590649942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4324085226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938066,0.0002012874,0.0040030153,0.00013886932,0.00029381027,0.0009808462,0.00022161941,0.00034664755,0.0000072887847],"genre_scores_gemma":[0.99709684,0.00039001647,0.0020786445,0.000029864075,0.00014442788,0.00010587644,9.641167e-7,0.0001422913,0.000011086102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965868,0.00025450153,0.0010194824,0.0009960253,0.00055777066,0.00058544404],"domain_scores_gemma":[0.9975331,0.00016010746,0.0009581617,0.0010171385,0.00021126465,0.00012023572],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000870357,0.0004737088,0.00069519697,0.0008088682,0.00010218189,0.000089202214,0.0008656141,0.0003948477,0.000011609582],"category_scores_gemma":[0.0012081304,0.0005391006,0.00016940126,0.00094052195,0.00023668834,0.00029923825,0.00072338793,0.00077356526,0.000017195534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025004743,0.000112034904,0.0022759892,0.0014141486,0.000018019258,0.000009665569,0.000089401874,0.020156894,0.97520685,0.0006824965,0.000007976665,0.0000015361409],"study_design_scores_gemma":[0.00073331385,0.000035489953,0.0060055857,0.0007637163,0.000014199656,2.0608557e-9,0.000012393894,0.03481717,0.95712703,0.000015410984,0.000014816838,0.0004608761],"about_ca_topic_score_codex":0.00017039219,"about_ca_topic_score_gemma":0.000025963169,"teacher_disagreement_score":0.01807981,"about_ca_system_score_codex":0.00020841749,"about_ca_system_score_gemma":0.00079132384,"threshold_uncertainty_score":0.99970603},"labels":[],"label_agreement":null},{"id":"W4324129396","doi":"10.1093/schbul/sbac201","title":"Association of Complement and Coagulation Pathway Proteins With Treatment Response in First-Episode Psychosis: A Longitudinal Analysis of the OPTiMiSE Clinical Trial","year":2023,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Regional Development Fund; Science Foundation Ireland; European Commission; National Institute for Health and Care Research; Health Research Board; Health Service Executive; Wellcome Trust; Canadian Institute for Theoretical Astrophysics","keywords":"Amisulpride; Complement system; C4A; Antipsychotic; Psychosis; Schizophrenia (object-oriented programming); Internal medicine; Complement (music); Medicine; Psychology; Oncology; Immunology; Immune system; Psychiatry; Phenotype","score_opus":0.059552448947290976,"score_gpt":0.32080416631801834,"score_spread":0.2612517173707274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4324129396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940249,0.00001315353,0.00002449872,0.004681993,0.00006915535,0.0010608783,0.00007170992,0.000025802034,0.00002792837],"genre_scores_gemma":[0.99927086,0.000041345094,0.0003234482,0.00003578289,0.000019052028,0.00013960947,0.0000067160695,0.000009670978,0.00015350136],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99776596,0.0007228281,0.00056656013,0.0003701495,0.0003859364,0.00018859515],"domain_scores_gemma":[0.99823374,0.00095425866,0.00043992256,0.0002935585,0.000036279762,0.000042273554],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001047719,0.00013358571,0.0003805439,0.00026678908,0.000090753354,0.0000192285,0.00014614916,0.000071278446,0.00007803559],"category_scores_gemma":[0.0008322268,0.00008937695,0.00016640044,0.0013670292,0.000113363545,0.000023425877,0.00005156103,0.00009746537,0.0000062331246],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.39225462,0.0024306655,0.5824133,0.000054491265,0.00069730513,0.000014353923,0.0012185713,0.009027989,0.0054609715,0.00055654,0.001275645,0.0045954967],"study_design_scores_gemma":[0.035688415,0.0016171157,0.9541484,0.000058423662,0.0001920617,4.519324e-7,0.00008020952,0.002147657,0.004758232,0.00005855656,0.0011190088,0.00013148425],"about_ca_topic_score_codex":0.00019805208,"about_ca_topic_score_gemma":0.0023455995,"teacher_disagreement_score":0.37173504,"about_ca_system_score_codex":0.000071815906,"about_ca_system_score_gemma":0.000039240083,"threshold_uncertainty_score":0.3644686},"labels":[],"label_agreement":null},{"id":"W4324359199","doi":"10.3390/brainsci13030490","title":"Oxidative Stress Biomarkers among Schizophrenia Inpatients","year":2023,"lang":"en","type":"article","venue":"Brain Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Oxidative stress; Schizophrenia (object-oriented programming); Positive and Negative Syndrome Scale; Internal medicine; Brain-derived neurotrophic factor; Psychosis; Medicine; Kynurenine; Psychology; Psychiatry; Endocrinology; Neurotrophic factors; Chemistry; Biochemistry; Receptor; Tryptophan","score_opus":0.0406274099935825,"score_gpt":0.2956014471942907,"score_spread":0.2549740372007082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4324359199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98748595,0.000014071564,0.000026587479,0.0016860917,0.00046503678,0.00023179426,0.00003642927,0.00033614115,0.009717904],"genre_scores_gemma":[0.998045,0.000013638084,0.00016739864,0.00083189516,0.000037786966,0.000022895401,0.0000039802662,0.0000111995205,0.0008661624],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99775755,0.00017576436,0.00019700939,0.00067105266,0.0006770284,0.000521596],"domain_scores_gemma":[0.9988211,0.00071616104,0.000103183454,0.00021238034,0.000019667701,0.00012750865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004451828,0.00015910192,0.00012806176,0.0003952771,0.0005836309,0.00019592799,0.00081423233,0.000051943945,0.00013024319],"category_scores_gemma":[0.0019492176,0.00013001454,0.000064644766,0.0033293467,0.0015681476,0.00056150113,0.00020607396,0.000095391326,0.0005077592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011930144,0.00027861595,0.0641831,0.000047006473,0.00002224603,0.00009668498,0.0043222057,0.0003676804,0.8041826,0.013675142,0.06026801,0.05243743],"study_design_scores_gemma":[0.0015738101,0.00037047005,0.2894068,0.000119665165,0.00000451057,0.000005105662,0.004199946,0.0046797274,0.685325,0.009794633,0.0037022403,0.0008180434],"about_ca_topic_score_codex":0.00004273431,"about_ca_topic_score_gemma":0.000052151594,"teacher_disagreement_score":0.2252237,"about_ca_system_score_codex":0.000016315478,"about_ca_system_score_gemma":0.00008057123,"threshold_uncertainty_score":0.65263873},"labels":[],"label_agreement":null},{"id":"W4324375426","doi":"10.3389/fnmol.2023.1048985","title":"Roxadustat (FG-4592) abated lipopolysaccharides-induced depressive-like symptoms via PI3K signaling","year":2023,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Natural Science Foundation of China","keywords":"Neuroinflammation; Wortmannin; Hypoxia (environmental); PI3K/AKT/mTOR pathway; Proinflammatory cytokine; Pharmacology; Cytokine; Inflammation; Medicine; Signal transduction; Endocrinology; Internal medicine; Chemistry; Cell biology; Biology","score_opus":0.018552449429386483,"score_gpt":0.2529995995367957,"score_spread":0.23444715010740919,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4324375426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9546027,0.00010106565,0.03912994,0.00028068657,0.0041725747,0.0006548474,0.000020669693,0.00069044746,0.00034702144],"genre_scores_gemma":[0.9956721,0.00007553603,0.0006034171,0.0031475956,0.00003822168,0.0000711017,0.0000068939135,0.000087577755,0.00029756996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9947998,0.0004735113,0.0005431433,0.0017169075,0.00107684,0.0013897826],"domain_scores_gemma":[0.9984696,0.00016050847,0.00021344108,0.0007916073,0.000039528313,0.00032535067],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004138566,0.00047627912,0.0004288997,0.0009485387,0.00050103344,0.00027054836,0.0016169945,0.00018055779,0.00002174993],"category_scores_gemma":[0.0012506463,0.00049569627,0.00015559394,0.0045682546,0.00050916226,0.0005676255,0.000402415,0.00071266986,0.00010554774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002676031,0.00011368832,0.0010860929,0.000017097927,0.000002514842,0.0010269579,0.00021766662,0.0031316904,0.98929054,0.000098580495,0.0012214587,0.0037669619],"study_design_scores_gemma":[0.00089588517,0.00020826602,0.001539298,0.000046938916,0.000009756268,0.000045860565,0.0001560819,0.05451371,0.9395761,0.0012560785,0.0010919811,0.0006600701],"about_ca_topic_score_codex":0.000047875372,"about_ca_topic_score_gemma":0.0000037433279,"teacher_disagreement_score":0.05138202,"about_ca_system_score_codex":0.0001019219,"about_ca_system_score_gemma":0.0001430219,"threshold_uncertainty_score":0.9997495},"labels":[],"label_agreement":null},{"id":"W4327705424","doi":"10.1016/j.jaclp.2022.09.002","title":"Catatonia Following Autologous Tumor-Infiltrating Immunotherapy and Interleukin-2 Infusions: A Case Report","year":2023,"lang":"en","type":"letter","venue":"Journal of the Academy of Consultation-Liaison Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Hazard ratio; Depression (economics); Meta-analysis; Internal medicine; Cohort study; Confidence interval; Cohort; Hematopoietic stem cell transplantation; Anxiety; Transplantation; Psychiatry","score_opus":0.02832344622724627,"score_gpt":0.31005321987129225,"score_spread":0.281729773644046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327705424","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.58951896,0.0021109493,0.000040456438,0.40230414,0.0052679717,0.0004945656,0.000050351093,0.0000647225,0.00014788898],"genre_scores_gemma":[0.40427774,0.0009154422,0.0043246867,0.58539855,0.0031232578,0.000042031068,0.000009919849,0.00029239352,0.0016159563],"study_design_codex":"not_applicable","study_design_gemma":"case_report","domain_scores_codex":[0.9958499,0.00045996156,0.0019724146,0.0004577351,0.000847196,0.0004127997],"domain_scores_gemma":[0.9934527,0.0020146011,0.0040138448,0.00032557425,0.00010942783,0.00008382316],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008419166,0.000428485,0.00078161404,0.0004923214,0.00041344622,0.00011756871,0.00092770124,0.0005485955,0.000021385356],"category_scores_gemma":[0.0036287978,0.00031725146,0.00059075555,0.0007896683,0.0003732779,0.00034418705,0.00013785333,0.003294375,0.000008270927],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022934683,0.00012050187,0.002386011,0.00054149295,0.0004758813,0.012864001,0.0036947078,0.00007913681,0.02264516,0.00033239977,0.953403,0.0032283578],"study_design_scores_gemma":[0.012219894,0.00075877097,0.0111714,0.0076530157,0.0007594574,0.536682,0.006150837,0.0005211862,0.01555016,0.027008452,0.37897128,0.0025535354],"about_ca_topic_score_codex":0.000038520568,"about_ca_topic_score_gemma":0.0000074503328,"teacher_disagreement_score":0.5744317,"about_ca_system_score_codex":0.00005663247,"about_ca_system_score_gemma":0.0005805528,"threshold_uncertainty_score":0.99992794},"labels":[],"label_agreement":null},{"id":"W4327739742","doi":"10.3390/brainsci13030505","title":"Biological Factors Underpinning Suicidal Behaviour: An Update","year":2023,"lang":"en","type":"review","venue":"Brain Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Health and Medical Research Council; Medical Research Council","keywords":"Underpinning; Public health; Psychology; Human factors and ergonomics; Poison control; Suicide prevention; Medicine; Psychiatry; Medical emergency; Pathology","score_opus":0.3986660044526517,"score_gpt":0.4410315859354854,"score_spread":0.0423655814828337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327739742","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010355251,0.98316973,0.00004746955,0.00044091462,0.0015713498,0.0011490155,0.00021024996,0.0012413545,0.0018146404],"genre_scores_gemma":[0.0016868195,0.99661666,0.00009118931,0.00078892417,0.00015432452,0.00004836963,0.00004733964,0.000057128385,0.00050922314],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99550164,0.0007249134,0.00059989735,0.0015897306,0.0006932545,0.00089056394],"domain_scores_gemma":[0.9971675,0.001781693,0.00035068011,0.0004336947,0.000014750163,0.0002516425],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010259916,0.0005521807,0.0010472614,0.00051678834,0.000781553,0.00048393858,0.0022234593,0.00035173516,0.00021015365],"category_scores_gemma":[0.0019124286,0.00035581685,0.00041720958,0.0024664665,0.001685122,0.00039776388,0.0003771721,0.00045875422,0.00057904166],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005672571,0.0003451966,0.00051092193,0.0018213537,0.00002779499,0.0002205412,0.0005867432,0.000011660208,0.00030060415,0.028729107,0.00587256,0.9615678],"study_design_scores_gemma":[0.00015660404,0.0003786898,0.00030222104,0.0013172104,0.000044438937,0.000056919176,0.000617176,0.000028583543,0.00014685796,0.0022549732,0.9933824,0.0013139436],"about_ca_topic_score_codex":0.00004876151,"about_ca_topic_score_gemma":0.0000415919,"teacher_disagreement_score":0.98750985,"about_ca_system_score_codex":0.000051661726,"about_ca_system_score_gemma":0.0003930559,"threshold_uncertainty_score":0.9998894},"labels":[],"label_agreement":null},{"id":"W4327909396","doi":"10.1101/2023.03.16.23287352","title":"Mechanistic convergence of depression and suicidality on astrocyte fatty acid metabolism","year":2023,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Common Fund; National Institute on Drug Abuse; National Human Genome Research Institute; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; NIH Office of the Director; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health","keywords":"Mendelian randomization; Genome-wide association study; Biology; Major depressive disorder; Computational biology; Genetic association; Gene; Transcriptome; Neuroscience; Genetics; Bioinformatics; Gene expression; Single-nucleotide polymorphism; Genotype; Genetic variants; Amygdala","score_opus":0.056678612827939685,"score_gpt":0.29366265487857807,"score_spread":0.2369840420506384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327909396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933414,0.00019961163,0.0038065522,0.00016518646,0.0014024072,0.0003854946,0.00015568362,0.00018289396,0.0003607708],"genre_scores_gemma":[0.9988779,0.00031589612,0.0002988319,0.00020762775,0.000056514207,0.000044464086,0.000007675127,0.00003920318,0.00015191494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975596,0.00026686292,0.00037931246,0.00096503034,0.0005072831,0.00032187917],"domain_scores_gemma":[0.9985432,0.00029900513,0.00028827426,0.0006945432,0.00004041617,0.00013457751],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034276716,0.00031609848,0.00047350826,0.00015453176,0.00009808467,0.000038637758,0.0005596611,0.00021471003,0.00008606823],"category_scores_gemma":[0.0012939824,0.00027518423,0.00012763355,0.00020461193,0.00021416938,0.00004863953,0.00084166677,0.000506684,0.00007176781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013168626,0.00009643793,0.0062186685,0.000367323,0.000015694573,0.000031928288,0.00019993505,0.00010631122,0.9871081,0.004281266,0.000092342525,0.0013502653],"study_design_scores_gemma":[0.00029488635,0.00003088862,0.11917104,0.00011749528,0.000021132668,0.0000023949924,0.000023595238,0.0005254892,0.87143004,0.008039391,0.00011967389,0.00022398897],"about_ca_topic_score_codex":0.000060143917,"about_ca_topic_score_gemma":0.000016883669,"teacher_disagreement_score":0.11567812,"about_ca_system_score_codex":0.0000156216,"about_ca_system_score_gemma":0.00006095396,"threshold_uncertainty_score":0.99997},"labels":[],"label_agreement":null},{"id":"W4360851420","doi":"10.3390/psychoactives2020007","title":"Application of Drug Efficiency Index Metric for Analysis of Post-Traumatic Stress Disorder and Treatment Resistant Depression Gene Expression Profiles","year":2023,"lang":"en","type":"article","venue":"Psychoactives","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Depression (economics); Gene; Gene expression; Drug; Microarray; Traumatic stress; Computational biology; Biology; Medicine; Psychiatry; Genetics","score_opus":0.023427378600958604,"score_gpt":0.31168227141477683,"score_spread":0.2882548928138182,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4360851420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903905,0.00028329666,0.008092869,0.00004776429,0.000029857898,0.0007682529,0.00023473307,0.000044204775,0.0001085375],"genre_scores_gemma":[0.9991503,0.00019556185,0.00031876232,0.0000067884102,0.0000067641304,0.00021622943,0.000034112927,0.000013390486,0.000058136065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998826,0.00008247318,0.00027275374,0.00042378702,0.00023021983,0.00016474279],"domain_scores_gemma":[0.9988154,0.0005497779,0.00025584685,0.0002857248,0.000048556874,0.0000447054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000096251555,0.00013565972,0.00028031634,0.00077970454,0.00010111673,0.000012549444,0.00014644954,0.000042891083,0.000007712475],"category_scores_gemma":[0.00016303729,0.000100095356,0.00011800126,0.0019955486,0.00010339586,0.000097030745,0.000030184703,0.000031306,8.7649727e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038882543,0.0007495172,0.030842522,0.00011013208,0.00007865826,2.1289654e-7,0.0032278216,0.0008506378,0.93962806,0.000085215506,0.000008446685,0.024029918],"study_design_scores_gemma":[0.00068201585,0.00013579342,0.38256177,0.000025584695,0.0000932332,1.00014105e-7,0.0025388363,0.008455254,0.60528624,0.00011056638,0.000016345559,0.00009426025],"about_ca_topic_score_codex":0.00010505647,"about_ca_topic_score_gemma":0.00005441581,"teacher_disagreement_score":0.35171923,"about_ca_system_score_codex":0.000015967495,"about_ca_system_score_gemma":0.000013750287,"threshold_uncertainty_score":0.40817702},"labels":[],"label_agreement":null},{"id":"W4360865690","doi":"10.3389/fphar.2023.1185593","title":"Editorial: Streaming inflammation: From damage to healing and resilience–Volume II","year":2023,"lang":"en","type":"editorial","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Inflammation; Resilience (materials science); Volume (thermodynamics); Medicine; Pharmacology; Internal medicine; Physics","score_opus":0.01060442678191197,"score_gpt":0.2905752042487753,"score_spread":0.27997077746686333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4360865690","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014957702,0.00015952003,0.00021925011,0.0009828563,0.98230267,0.00056914514,0.00037576718,0.00023438357,0.00019869769],"genre_scores_gemma":[0.000667334,0.00066481467,0.0008277317,0.00024819493,0.99551153,0.00014716401,0.0001269099,0.00009239495,0.0017139066],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963352,0.0003974246,0.0005798217,0.0012254284,0.00071627065,0.00074583094],"domain_scores_gemma":[0.997925,0.0012359944,0.00023129644,0.00029186855,0.00006946848,0.00024636812],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004415031,0.00042087873,0.0006540176,0.0006284607,0.00032394475,0.000097602446,0.0007850764,0.0008996931,0.000087001215],"category_scores_gemma":[0.0031729164,0.00048293578,0.000070706556,0.00074049755,0.00025836023,0.00025099426,0.00059707597,0.0012637068,0.00006972633],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020528688,0.00003084853,0.000064042084,0.000043492317,0.000016751383,0.000061076236,0.00079944526,0.0002538571,0.017482018,0.000003817563,0.9782258,0.0028135392],"study_design_scores_gemma":[0.0014118019,0.0001353524,0.000062823376,0.00006946506,0.000027632514,2.0861172e-7,0.00022997479,0.00072564586,0.004773482,0.00054131774,0.9915799,0.00044243102],"about_ca_topic_score_codex":0.00023677186,"about_ca_topic_score_gemma":0.000087978544,"teacher_disagreement_score":0.014290368,"about_ca_system_score_codex":0.00024999116,"about_ca_system_score_gemma":0.0003206469,"threshold_uncertainty_score":0.99976224},"labels":[],"label_agreement":null},{"id":"W4361302814","doi":"10.1016/j.clinsp.2023.100188","title":"The relationship of major depressive disorder with Crohn's disease activity","year":2023,"lang":"en","type":"article","venue":"Clinics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Major depressive disorder; Medicine; Internal medicine; Disease; Psychiatry; Depression (economics); Crohn's disease; Clinical psychology","score_opus":0.05346693468863724,"score_gpt":0.3277502547945672,"score_spread":0.27428332010593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361302814","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996997,0.000055104338,0.00015685974,0.0014703913,0.00014469864,0.00020861177,0.000026168373,0.00008904098,0.00085211697],"genre_scores_gemma":[0.99797136,0.00008133162,0.000012270585,0.00015181741,0.000021465128,0.00002540593,0.0000018631829,0.0000147140745,0.0017197743],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991481,0.000118839955,0.00013631301,0.00022359497,0.0001943752,0.00017881913],"domain_scores_gemma":[0.99615765,0.003267481,0.000118937074,0.00036167042,0.000022376691,0.000071918235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014078754,0.000079073885,0.00008501314,0.000033744785,0.00031125732,0.000028774099,0.00023310016,0.000034897064,0.00001130871],"category_scores_gemma":[0.0032900185,0.000049543643,0.000058795085,0.00042746105,0.00030988542,0.00009470564,0.00007127974,0.00015060548,0.000078455705],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032810813,0.00086761644,0.8019931,0.0002073427,0.0000460981,0.00028301319,0.0010717226,0.0017075259,0.0037064732,0.10408532,0.008322989,0.07442774],"study_design_scores_gemma":[0.0006403875,0.000041830615,0.9858872,0.000016572663,0.0000102311515,4.755983e-7,0.00008786821,0.00073791906,0.00096065376,0.008176059,0.0033480509,0.00009270367],"about_ca_topic_score_codex":0.0000033401968,"about_ca_topic_score_gemma":0.00002936888,"teacher_disagreement_score":0.18389416,"about_ca_system_score_codex":0.0000051220445,"about_ca_system_score_gemma":0.000076176075,"threshold_uncertainty_score":0.3938697},"labels":[],"label_agreement":null},{"id":"W4362523911","doi":"10.1186/s12888-023-04718-8","title":"Study on correlations of BDNF, PI3K, AKT and CREB levels with depressive emotion and impulsive behaviors in drug-naïve patients with first-episode schizophrenia","year":2023,"lang":"en","type":"article","venue":"BMC Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); CREB; Protein kinase B; Psychology; Internal medicine; PI3K/AKT/mTOR pathway; Brain-derived neurotrophic factor; Psychiatry; Clinical psychology; Pathogenesis; Positive and Negative Syndrome Scale; Medicine; Endocrinology; Neurotrophic factors; Psychosis; Signal transduction; Receptor; Biology; Transcription factor; Gene; Genetics","score_opus":0.019341337691734257,"score_gpt":0.25920507882325433,"score_spread":0.23986374113152006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362523911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983483,0.000021553346,0.000059059003,0.00009958619,0.0002008078,0.0009877675,0.00007354001,0.000057554706,0.00015181837],"genre_scores_gemma":[0.9994238,0.0000050301883,0.00035238458,0.000055824898,0.000017343273,0.00005319171,0.000008285693,0.000027823702,0.000056317473],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99860823,0.00010664219,0.00023534831,0.0005129378,0.00030629922,0.0002305131],"domain_scores_gemma":[0.9992858,0.00017564105,0.00017503985,0.00024985205,0.00003520854,0.00007841984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000065771535,0.00020091062,0.00020639009,0.00028025045,0.00018011424,0.00003210734,0.00012147892,0.0000542127,0.000007251354],"category_scores_gemma":[0.00009343808,0.00015739759,0.000023271914,0.00065795676,0.00015821666,0.00018120851,0.000060626215,0.00017491725,0.000007752629],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003954025,0.00075668894,0.9962233,0.000031328127,0.0000064413553,0.000002087008,0.001681935,0.00026593098,0.000059753755,0.0002610012,0.00015126828,0.00016489957],"study_design_scores_gemma":[0.005523193,0.0009071441,0.990084,0.00015102708,0.000024344785,0.0000029096773,0.0025081092,0.00006833814,0.00026691615,0.00026647575,0.0000025100148,0.00019502026],"about_ca_topic_score_codex":0.00011365071,"about_ca_topic_score_gemma":0.0041536093,"teacher_disagreement_score":0.0061392514,"about_ca_system_score_codex":0.000015094601,"about_ca_system_score_gemma":0.00005618264,"threshold_uncertainty_score":0.64184874},"labels":[],"label_agreement":null},{"id":"W4362541389","doi":"10.1158/1538-7445.am2023-3539","title":"Abstract 3539: Indoleamine-2,3-dioxygenase 2 (IDO-2) is expressed in hepatoblastoma cells and associated with metastatic state","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Hepatoblastoma; Medicine; Kynurenine; Carcinogenesis; Malignancy; Cancer research; Immune system; Internal medicine; Cancer; Immunology; Biology; Tryptophan","score_opus":0.09905565641191566,"score_gpt":0.36813709566273617,"score_spread":0.2690814392508205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362541389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99809283,0.00010809148,0.0000021439896,0.0004740832,0.00004559707,0.00049351907,0.000274992,0.000100619174,0.00040809775],"genre_scores_gemma":[0.9972943,0.00066933595,0.000006983581,0.00028551044,0.000015701038,0.00018855161,0.0000050238045,0.000044450964,0.0014901463],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971653,0.00030001183,0.00022010549,0.00062442187,0.00084057025,0.0008495716],"domain_scores_gemma":[0.9984428,0.0009448146,0.000059675098,0.00027735985,0.000081286715,0.0001940609],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007565664,0.00017427442,0.00023203933,0.0005194062,0.00016625343,0.00013398004,0.0003148908,0.000049213544,0.00019696602],"category_scores_gemma":[0.000516224,0.00014695819,0.000030117886,0.0021585848,0.00034746903,0.0002096237,0.00014570127,0.00051531533,0.00014322992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022947557,0.00011603076,0.00064642285,0.0000972843,0.00001528742,0.00044127344,0.0016559165,0.00017228838,0.9874168,0.000013785872,0.0059253476,0.0032700924],"study_design_scores_gemma":[0.0018387799,0.00013150567,0.035691544,0.00015972933,0.0000013741262,0.0000012682672,0.00049377646,0.00057728786,0.95941556,0.00040872843,0.0010678894,0.00021256012],"about_ca_topic_score_codex":0.0004644754,"about_ca_topic_score_gemma":0.0010318162,"teacher_disagreement_score":0.03504512,"about_ca_system_score_codex":0.00012000563,"about_ca_system_score_gemma":0.00024198028,"threshold_uncertainty_score":0.59927815},"labels":[],"label_agreement":null},{"id":"W4362659676","doi":"10.1093/schbul/sbad031","title":"Review of Major Social Determinants of Health in Schizophrenia-Spectrum Psychotic Disorders: III. Biology","year":2023,"lang":"en","type":"letter","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; Stanley Medical Research Institute; National Institutes of Health; National Institute of General Medical Sciences; National Institute of Mental Health; Universidad de Costa Rica; International Life Sciences Institute","keywords":"Schizophrenia (object-oriented programming); Psychology; Neurocognitive; Quality of life (healthcare); Allostatic load; Psychiatry; Medicine; Clinical psychology; Cognition; Neuroscience; Psychotherapist","score_opus":0.03344635319686313,"score_gpt":0.3102121194332039,"score_spread":0.2767657662363408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362659676","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0095993485,0.022022989,0.000023569837,0.96246403,0.0019788763,0.0023008264,0.0007952122,0.0002758635,0.0005392825],"genre_scores_gemma":[0.037755046,0.10494876,0.00084344967,0.8508613,0.002445238,0.0004465903,0.00050992006,0.00066006166,0.0015296324],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99276215,0.0014439727,0.0025083665,0.0014702842,0.00055048475,0.0012647358],"domain_scores_gemma":[0.99624574,0.0006838154,0.002000434,0.000931508,0.000048070953,0.00009041643],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001042789,0.0007997946,0.0024523,0.00091461587,0.00018309998,0.000025267875,0.0015471966,0.0008639464,0.0008209416],"category_scores_gemma":[0.00091733725,0.000777083,0.00062955247,0.0015279233,0.0007888284,0.000047656562,0.00031090074,0.0020827826,0.00045060256],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046645995,0.00020600202,0.000057433022,0.011970813,0.000025807265,0.00003812894,0.000108624336,3.4761868e-7,0.00037233657,0.00043880288,0.9606017,0.025713567],"study_design_scores_gemma":[0.0098562995,0.0008497104,0.0019858538,0.024434678,0.000076720076,0.00003873981,0.000049031714,0.000011349486,0.0015348631,0.01808567,0.9411808,0.0018962689],"about_ca_topic_score_codex":0.00048569802,"about_ca_topic_score_gemma":0.00038038258,"teacher_disagreement_score":0.11160273,"about_ca_system_score_codex":0.00009430976,"about_ca_system_score_gemma":0.00048459598,"threshold_uncertainty_score":0.999468},"labels":[],"label_agreement":null},{"id":"W4362733805","doi":"10.1016/j.biopsych.2023.02.704","title":"464. Brain Transcriptomic Signatures of Race in Schizophrenia (SCZ) and Controls","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia (object-oriented programming); Race (biology); Transcriptome; Psychology; Neuroscience; Incidence (geometry); Psychosis; Psychiatry; Clinical psychology; Medicine; Biology; Genetics; Gene; Gene expression","score_opus":0.02893546999139753,"score_gpt":0.27610773672926436,"score_spread":0.24717226673786682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362733805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927135,0.0010051694,0.000016647567,0.004879284,0.00039751275,0.00025614045,0.000032819993,0.00012737111,0.00057155255],"genre_scores_gemma":[0.9972493,0.00019416134,0.00015432444,0.0022388585,0.000054641983,0.000013482834,0.0000035480568,0.000008698163,0.00008297961],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987578,0.0001921484,0.00025154997,0.00040675627,0.000108280554,0.0002834914],"domain_scores_gemma":[0.9992928,0.00043394507,0.000059815982,0.00014217093,0.0000059531476,0.0000653056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021012571,0.0001422896,0.0002517321,0.00013449302,0.000049072467,0.000015008634,0.00022768378,0.00018243409,0.00005650643],"category_scores_gemma":[0.00045958025,0.00010176056,0.000078983954,0.0004934598,0.00026006173,0.000048748476,0.000038006867,0.00021857546,0.000031011536],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068070984,0.00015964136,0.011587672,0.00003137858,0.0000047367485,0.000007776585,0.00009910767,0.000017083972,0.9569797,0.022487756,0.0046948693,0.003249601],"study_design_scores_gemma":[0.0075352583,0.00074099493,0.9044392,0.000080459016,0.000005297719,0.000009265215,0.00035793328,0.00043624526,0.017716119,0.06358724,0.0045691957,0.000522771],"about_ca_topic_score_codex":0.000007238398,"about_ca_topic_score_gemma":0.000030155072,"teacher_disagreement_score":0.9392635,"about_ca_system_score_codex":0.0000051219163,"about_ca_system_score_gemma":0.000028717695,"threshold_uncertainty_score":0.41496754},"labels":[],"label_agreement":null},{"id":"W4362733822","doi":"10.1016/j.biopsych.2023.02.636","title":"396. Clozapine Demethylation and Astrocyte Activity in Treatment Resistant Schizophrenia: A Proton Magnetic Resonance Spectroscopy Study","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Clozapine; Schizophrenia (object-oriented programming); Glutamate receptor; Glutamatergic; Psychosis; Astrocyte; Medicine; Pharmacology; Antipsychotic; Psychology; Internal medicine; Psychiatry; Central nervous system; Receptor","score_opus":0.04571848671278692,"score_gpt":0.30406063370646913,"score_spread":0.2583421469936822,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362733822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961202,0.00094432296,0.000009622636,0.0007269274,0.00019072824,0.0016004944,0.000016143602,0.00018386914,0.00020766436],"genre_scores_gemma":[0.9983206,0.00062582904,0.0005023576,0.00009707079,0.00007985782,0.0002774675,0.0000023251416,0.0000114021395,0.000083103005],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9982224,0.00033164478,0.00022254101,0.0007063236,0.00015588985,0.0003611741],"domain_scores_gemma":[0.99949247,0.0001305311,0.000064557644,0.00023105035,0.0000065627396,0.000074808224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019170975,0.0002097402,0.00023952196,0.0001338724,0.00013600856,0.00003545202,0.00014060401,0.00010044991,0.00003351326],"category_scores_gemma":[0.00016078554,0.00014773244,0.000049741626,0.00070597144,0.00012463372,0.000064970416,0.0000713125,0.00016387126,0.00004307745],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0068979445,0.002479748,0.36878952,0.000034101635,0.000006196189,0.000051099374,0.00023861854,0.0000067926608,0.5769094,0.001132547,0.00016269682,0.043291286],"study_design_scores_gemma":[0.0032353012,0.0045066113,0.97687364,0.000017488252,0.0000034705718,0.000001987809,0.00013449103,0.00012166418,0.011394713,0.0022625062,0.0012636448,0.00018449085],"about_ca_topic_score_codex":0.00003645393,"about_ca_topic_score_gemma":0.00022112722,"teacher_disagreement_score":0.6080841,"about_ca_system_score_codex":0.000054174605,"about_ca_system_score_gemma":0.000043954224,"threshold_uncertainty_score":0.6024354},"labels":[],"label_agreement":null},{"id":"W4362733986","doi":"10.1016/j.biopsych.2023.02.254","title":"14. Frequency of Cannabis-Use, Neurocognitive Performance and Functioning in Clinical High-Risk Participants From the NAPLS-3 Cohort: Moderate Use is Associated With Better Performance and Functioning","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Neurocognitive; Psychosocial; Cannabis; Cohort; Psychology; Social functioning; Psychiatry; Clinical psychology; Medicine; Cognition; Internal medicine","score_opus":0.07149765530219496,"score_gpt":0.2772743222814459,"score_spread":0.20577666697925093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362733986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982024,0.00005085219,0.00002755454,0.00069725624,0.0004462854,0.00033194112,0.00011119229,0.00008953924,0.00004300228],"genre_scores_gemma":[0.9962784,0.0006418709,0.00008814854,0.0027632352,0.00007569806,0.000043969845,0.00001899752,0.00001615161,0.00007349351],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99783164,0.0004279623,0.0004672459,0.0006576571,0.0001902656,0.00042520178],"domain_scores_gemma":[0.9984257,0.0009788426,0.00025841297,0.00019393844,0.000052372463,0.0000907355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045507523,0.00021643627,0.00031589845,0.00006105811,0.0003673475,0.00009215661,0.00013153945,0.00018362123,0.00002830424],"category_scores_gemma":[0.0011939368,0.00013241281,0.000046157747,0.00052969216,0.00052035396,0.00036107376,0.00009354853,0.000531532,0.000011454545],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000282302,0.00007424052,0.9968719,0.000005928539,0.000027901331,0.0000028841978,0.00014730671,0.000061428145,0.00032325127,0.000030515726,0.00055278244,0.0016195904],"study_design_scores_gemma":[0.0011525656,0.0005029077,0.9936736,0.00008917232,0.000026343825,0.000002066932,0.00011290521,0.0036701788,0.00016926545,0.00037139704,0.000037863734,0.00019171275],"about_ca_topic_score_codex":0.0002625572,"about_ca_topic_score_gemma":0.00029258305,"teacher_disagreement_score":0.0036087506,"about_ca_system_score_codex":0.000012414391,"about_ca_system_score_gemma":0.000049583297,"threshold_uncertainty_score":0.5399638},"labels":[],"label_agreement":null},{"id":"W4363648493","doi":"10.1016/j.biopsych.2023.02.271","title":"31. Understanding the Dissociative PTSD Subtype: Distinct Relations Between Early-Life Trauma, Neuroendocrine, and Inflammatory Profiles","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa; Carleton University","funders":"","keywords":"Dissociative; Psychology; Clinical psychology; Posttraumatic stress; Acute Stress Disorder; Psychiatry; Medicine","score_opus":0.08872073757249159,"score_gpt":0.2956561483664533,"score_spread":0.20693541079396172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4363648493","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98904234,0.00009124528,0.00012651303,0.0059285997,0.0003798599,0.0003782992,0.000081233076,0.00033434993,0.0036375665],"genre_scores_gemma":[0.99888617,0.000036343485,0.000023694505,0.0004619653,0.00017725136,0.000031612235,0.0000134030415,0.000015074843,0.00035448652],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984126,0.00032909782,0.00025586155,0.00044490088,0.00017461879,0.0003828923],"domain_scores_gemma":[0.9985152,0.0010432602,0.0001227514,0.00018482837,0.000008765964,0.00012518784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018236613,0.00018202678,0.00017603723,0.00006824125,0.0006284599,0.000070665126,0.00026698454,0.00007653587,0.00004277166],"category_scores_gemma":[0.0010111231,0.00011079033,0.00009173684,0.0005344132,0.00046697617,0.00009439746,0.00012563258,0.0003257249,0.00014490735],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029265715,0.000037259335,0.93893725,0.000012576447,0.000013793437,0.0000065577096,0.00028561964,0.0000027831093,0.00076745247,0.055018216,0.0045498703,0.00033936749],"study_design_scores_gemma":[0.0003316456,0.00009948065,0.96603066,0.0000111085565,0.000007717785,0.000002045025,0.00096873706,0.000028905724,0.000073600146,0.031700242,0.00058735185,0.00015852705],"about_ca_topic_score_codex":0.000007075624,"about_ca_topic_score_gemma":0.00001917131,"teacher_disagreement_score":0.0270934,"about_ca_system_score_codex":0.00003381698,"about_ca_system_score_gemma":0.000047070345,"threshold_uncertainty_score":0.48336694},"labels":[],"label_agreement":null},{"id":"W4363648560","doi":"10.1016/j.biopsych.2023.02.644","title":"404. Disentangling the Depression-Suicide Relationship Among Emerging Adults: The Role of Symptom Clusters and Inflammatory Biomarkers","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Carleton University","funders":"","keywords":"Depression (economics); Suicidal ideation; Clinical psychology; Depressive symptoms; Psychology; Psychiatry; Medicine; Suicide prevention; Poison control; Medical emergency; Anxiety","score_opus":0.020216745770675938,"score_gpt":0.2597366337340051,"score_spread":0.23951988796332913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4363648560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99566203,0.0009813128,0.000011852525,0.0013538662,0.0003501976,0.00031019913,0.000010511129,0.00014424468,0.0011757709],"genre_scores_gemma":[0.99922544,0.00014016373,0.000034740828,0.00045421527,0.00008113061,0.000028432809,0.0000041577455,0.000011259453,0.000020488065],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986598,0.00026853755,0.00028169187,0.00034905548,0.0001734361,0.0002674599],"domain_scores_gemma":[0.9984569,0.0010359951,0.00014833138,0.00028479134,0.000011199928,0.00006276456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030075505,0.0001431956,0.00011819648,0.00006766248,0.00044834494,0.000031375283,0.00037163246,0.00010962203,0.000017683418],"category_scores_gemma":[0.0006510743,0.00007045469,0.00009787083,0.00048714547,0.0005672713,0.000078393576,0.00018357513,0.00018446533,0.00001447543],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008012855,0.000020305864,0.9918578,0.00001260542,0.000008540282,0.0000010595508,0.0003089213,0.000046862366,0.0024937624,0.0022554032,0.00036716627,0.0025474236],"study_design_scores_gemma":[0.000350004,0.00003011016,0.9835252,0.00008409225,0.0000072325597,0.0000031481586,0.0052880626,0.0022419607,0.00068716577,0.0073188734,0.0003332356,0.00013089791],"about_ca_topic_score_codex":0.000009918022,"about_ca_topic_score_gemma":0.00002569375,"teacher_disagreement_score":0.008332605,"about_ca_system_score_codex":0.000007784858,"about_ca_system_score_gemma":0.000018974515,"threshold_uncertainty_score":0.34483522},"labels":[],"label_agreement":null},{"id":"W4363675358","doi":"10.1016/j.biopsych.2023.02.526","title":"286. Genetic Polymorphism of Brain-Derived Neurotrophic Factor is Related to Antidepressant Efficacy and Treatment-Induced Hippocampal Plasticity in Patients With Major Depressive Disorder: CAN-BIND-1 Study","year":2023,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Simon Fraser University; University of British Columbia; McGill University; University of Calgary; Dalhousie University; University of Toronto; McMaster University; Queen's University","funders":"","keywords":"rs6265; Antidepressant; Neurotrophic factors; Brain-derived neurotrophic factor; Major depressive disorder; Neuroplasticity; Hippocampal formation; Psychology; Hippocampus; Neuroscience; Polymorphism (computer science); Internal medicine; Medicine; Allele; Endocrinology; Biology; Cognition; Genetics; Receptor; Gene","score_opus":0.027348149448375835,"score_gpt":0.2642999470726908,"score_spread":0.23695179762431495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4363675358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99685705,0.000036956226,0.000003203484,0.0007362335,0.00023559127,0.0018283459,0.00015047617,0.00013100439,0.0000211142],"genre_scores_gemma":[0.99918795,0.000022382641,0.000038799317,0.00061280985,0.000018399855,0.00006578345,0.000008771854,0.000031196127,0.000013905053],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974162,0.00032144022,0.0004507484,0.0010020811,0.000276455,0.0005330598],"domain_scores_gemma":[0.9988763,0.00039906977,0.00017374518,0.0003196922,0.000024472156,0.00020676423],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00003185393,0.00038108104,0.00047439738,0.00024646107,0.00015693804,0.000029080866,0.0003085301,0.00016409355,0.00005020636],"category_scores_gemma":[0.00035361917,0.00025234756,0.000069044545,0.0008496585,0.00017473158,0.000046727335,0.0001552154,0.00020287638,0.000022822638],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091460213,0.0018469905,0.9530198,0.0000088346715,0.000029695992,0.000025257403,0.0006168858,0.00003657898,0.041929323,0.000018158193,0.000024384712,0.0015294966],"study_design_scores_gemma":[0.009028856,0.005328702,0.9827773,0.000027814389,0.000014977838,0.000001854087,0.00015000413,0.000030195522,0.002186817,0.00014018198,0.0000052098485,0.0003081018],"about_ca_topic_score_codex":0.00015186766,"about_ca_topic_score_gemma":0.00013005854,"teacher_disagreement_score":0.039742507,"about_ca_system_score_codex":0.000025768875,"about_ca_system_score_gemma":0.000061688406,"threshold_uncertainty_score":0.99999285},"labels":[],"label_agreement":null},{"id":"W4364352285","doi":"10.22074/cellj.2023.557498.1056","title":"Distribution of Plasma One-Carbon Metabolism Factors and Amino Acids Profile in Depression State Treated with Paroxetine: A Model Study.","year":2023,"lang":"en","type":"article","venue":"PubMed","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Royan Institute","keywords":"Paroxetine; Ornithine; Internal medicine; Endocrinology; Citrulline; Chemistry; Phenylalanine; Metabolism; Arginine; Metabolite; Urea cycle; Amino acid; Medicine; Biochemistry; Serotonin","score_opus":0.03385528881275719,"score_gpt":0.23230806365496076,"score_spread":0.19845277484220358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4364352285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983828,0.000011822962,0.0000096713175,0.000023785216,0.00002177001,0.0011485458,0.00009363156,0.00010839271,0.00019958027],"genre_scores_gemma":[0.9990729,0.000025043415,0.000005250773,0.000006682482,0.0000041238254,0.0006591379,0.000024721032,0.000015411111,0.00018672913],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99873406,0.00009767161,0.0001939949,0.00036717203,0.00026471567,0.00034238535],"domain_scores_gemma":[0.9995631,0.000089714114,0.00008644597,0.00016027673,0.000017314123,0.000083143765],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013946123,0.00014711908,0.00021823005,0.00013309417,0.00004241538,0.000022919137,0.00010783599,0.00004038317,0.0000012860082],"category_scores_gemma":[0.00021539125,0.00010671972,0.000019765523,0.00070249813,0.00008137226,0.00012007536,0.000072156356,0.00010019191,7.812587e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00079125207,0.000832089,0.94952005,0.00006199136,0.000021262242,0.000024163457,0.002035608,0.0015412389,0.027476663,0.000046289046,0.00002700382,0.017622383],"study_design_scores_gemma":[0.0014258771,0.000031652406,0.82880604,0.0000066918024,0.000009916473,4.6099973e-7,0.00014381912,0.009098756,0.16032274,0.00004271227,0.000007048893,0.00010427128],"about_ca_topic_score_codex":0.00010483723,"about_ca_topic_score_gemma":0.000064902175,"teacher_disagreement_score":0.13284609,"about_ca_system_score_codex":0.00001875356,"about_ca_system_score_gemma":0.00001525183,"threshold_uncertainty_score":0.4351904},"labels":[],"label_agreement":null},{"id":"W4366597451","doi":"10.3390/biom13040695","title":"Connecting Dots between Mitochondrial Dysfunction and Depression","year":2023,"lang":"en","type":"review","venue":"Biomolecules","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation; Fondation de la recherche en santé du Nouveau-Brunswick","keywords":"Oxidative stress; Neuroinflammation; Depression (economics); Mitochondrion; Pathophysiology; Neuroscience; Apoptosis; Neuroplasticity; Disease; Biology; Medicine; Bioinformatics; Cell biology; Internal medicine; Endocrinology; Biochemistry","score_opus":0.09809922820856427,"score_gpt":0.3477942394031238,"score_spread":0.24969501119455956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366597451","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041260791,0.9967371,0.00030740074,0.000019339628,0.0010806031,0.000590398,0.00008409828,0.00035492954,0.00041347908],"genre_scores_gemma":[0.00017866612,0.9987917,0.00008505891,0.00002908311,0.00060064025,0.000038817358,0.000044754128,0.00007975149,0.00015152524],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99823976,0.00022600713,0.00033496015,0.0007053329,0.00021391248,0.00028000647],"domain_scores_gemma":[0.9987858,0.00064117636,0.0002229095,0.00024174056,0.000011938565,0.00009644308],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000073585004,0.0003128315,0.00064227317,0.00023399449,0.00020328171,0.00012711647,0.00022742354,0.00028260364,0.000016288064],"category_scores_gemma":[0.0010337338,0.0002484213,0.00019107929,0.00045442267,0.000091673275,0.00007065051,0.00019955401,0.00021080443,0.00024731515],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000034961006,0.000009660147,0.000001475015,0.002468491,0.000014942832,0.000025289643,0.000025325635,4.4814534e-8,0.0015056316,0.00009875324,0.00045064933,0.99539626],"study_design_scores_gemma":[0.00034193104,0.00003955207,0.000010102946,0.004772331,0.00014860676,0.000035158333,0.000038076752,0.0000038716303,0.0027411883,0.00022776597,0.99117976,0.00046167706],"about_ca_topic_score_codex":0.000017600201,"about_ca_topic_score_gemma":0.0000077843715,"teacher_disagreement_score":0.99493456,"about_ca_system_score_codex":0.000024990131,"about_ca_system_score_gemma":0.000046647943,"threshold_uncertainty_score":0.9999968},"labels":[],"label_agreement":null},{"id":"W4366603148","doi":"10.1007/s13311-023-01376-2","title":"The Promise of Niacin in Neurology","year":2023,"lang":"en","type":"review","venue":"Neurotherapeutics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Niacin; Medicine; Multiple sclerosis; Neurology; Pharmacology; Internal medicine; Immunology; Psychiatry","score_opus":0.1689015393039163,"score_gpt":0.3807627803969657,"score_spread":0.2118612410930494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366603148","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000095777126,0.99622786,0.0000020060668,0.00028941402,0.0006213727,0.001465934,0.000027312242,0.000108129294,0.0011621728],"genre_scores_gemma":[0.000030429603,0.9981665,0.0000026300318,0.0008349599,0.000046319343,0.00011918691,0.0000011035478,0.00011114898,0.00068771216],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99749666,0.0007199871,0.00064578553,0.00048480366,0.00024613724,0.00040662332],"domain_scores_gemma":[0.9969395,0.0020981142,0.00031418135,0.00059703423,0.000011645357,0.000039554052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020428924,0.00030777798,0.00079866254,0.00020462678,0.00007842301,0.000033256147,0.0008672959,0.00023059946,0.000010896171],"category_scores_gemma":[0.0003473266,0.00020156814,0.00026894678,0.0009921405,0.00029418262,0.000026298747,0.00008329543,0.0006691102,0.00013214376],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021172598,0.00006918708,0.000002716336,0.0023622615,0.0000099039735,0.000045280995,0.000059929138,0.0000020717969,0.0001224081,0.0019350852,0.0001558591,0.9952141],"study_design_scores_gemma":[0.00019905379,0.00010330173,0.000009534013,0.0004054762,0.000023754585,0.0000195853,0.0000030385256,0.000021842383,0.000102566795,0.00045714635,0.99850255,0.00015215407],"about_ca_topic_score_codex":0.000003985681,"about_ca_topic_score_gemma":0.000030121377,"teacher_disagreement_score":0.9983467,"about_ca_system_score_codex":0.000011698607,"about_ca_system_score_gemma":0.00016901855,"threshold_uncertainty_score":0.821971},"labels":[],"label_agreement":null},{"id":"W4366754148","doi":"10.1016/j.bbih.2023.100628","title":"Sex-specific effects of voluntary wheel running on behavior and the gut microbiota-immune-brain axis in mice","year":2023,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; McGill University; Douglas Mental Health University Institute; Carleton University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Anxiety; Gut–brain axis; Gut flora; Wheel running; Open field; Immune system; Turnover; Depression (economics); Elevated plus maze; Physiology; Hippocampus; Medicine; Mental health; Internal medicine; Psychology; Immunology; Psychiatry","score_opus":0.02973349030373946,"score_gpt":0.2976043231349766,"score_spread":0.26787083283123714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366754148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907206,0.0009577848,0.0000041237695,0.0051394687,0.00045731684,0.002354444,0.000074147414,0.00019458192,0.000097517775],"genre_scores_gemma":[0.99401695,0.000554463,0.0000625237,0.004079129,0.00003269671,0.00029380844,0.000050227674,0.000077582394,0.0008325966],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99535805,0.001710711,0.0008665297,0.0006957703,0.0004435972,0.00092536455],"domain_scores_gemma":[0.99518913,0.003298765,0.00035076131,0.0009597833,0.000032621545,0.00016891732],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001992106,0.00043189756,0.00074240245,0.0005595398,0.00070439756,0.00008824272,0.000850657,0.00018947307,0.00004161778],"category_scores_gemma":[0.0005900364,0.00037273014,0.00019558256,0.001437002,0.00086743565,0.0001953682,0.00038493378,0.0011094477,0.00006324421],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032467526,0.0010178019,0.006552759,0.0002994563,0.0000066602443,0.00010017556,0.010379179,0.000006124984,0.9432393,0.00074183824,0.0042591705,0.03307289],"study_design_scores_gemma":[0.006276417,0.0005704104,0.9309355,0.00036749613,0.000016910766,0.00004909461,0.002471934,0.000030934694,0.0560504,0.00008210756,0.0026765857,0.0004722262],"about_ca_topic_score_codex":0.003514077,"about_ca_topic_score_gemma":0.00032466225,"teacher_disagreement_score":0.92438275,"about_ca_system_score_codex":0.00016819921,"about_ca_system_score_gemma":0.00018857664,"threshold_uncertainty_score":0.99987245},"labels":[],"label_agreement":null},{"id":"W4366768683","doi":"10.1101/2023.04.21.537733","title":"Transcriptional dissection of symptomatic profiles across the brain of men and women with depression","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Université Laval","funders":"National Institute of Mental Health; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Major depressive disorder; Neuroscience; Biology; Glutamatergic; Gene; Depression (economics); Gene expression; Psychology; Bioinformatics; Genetics; Receptor; Cognition; Glutamate receptor","score_opus":0.01718459772938096,"score_gpt":0.23836958767284808,"score_spread":0.2211849899434671,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366768683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980135,0.0001303319,0.0003318747,0.00023536934,0.00017716641,0.00069519266,0.00025609683,0.00015378096,0.000006677965],"genre_scores_gemma":[0.9993319,0.00007287327,0.00016449983,0.00005686699,0.000045082044,0.00025771846,1.1973904e-7,0.00006011648,0.000010854072],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980834,0.00017399441,0.00037218508,0.00060382497,0.00043378831,0.00033278693],"domain_scores_gemma":[0.9986181,0.00026793228,0.00037007267,0.00055135967,0.00010264573,0.00008988706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046167948,0.00027751052,0.00035303674,0.000110774214,0.00015995589,0.00007146951,0.00038951592,0.0001804364,0.000014108206],"category_scores_gemma":[0.00030964043,0.00019702959,0.00005469567,0.00044931204,0.00042464238,0.000119220975,0.0002030676,0.00030804516,0.0000031537454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010959078,0.00009121716,0.004822861,0.0007219988,0.00003468842,0.0000042168685,0.00032599588,0.00006648042,0.99346566,0.00030480375,0.000048096852,0.0000043819373],"study_design_scores_gemma":[0.00042583208,0.00006997168,0.3797952,0.0003878941,0.000012873227,3.382414e-8,0.00008967934,0.00028312512,0.6186877,0.000015201335,0.000035498062,0.0001969795],"about_ca_topic_score_codex":0.000024304243,"about_ca_topic_score_gemma":0.0000030339147,"teacher_disagreement_score":0.37497234,"about_ca_system_score_codex":0.00005235922,"about_ca_system_score_gemma":0.00015502286,"threshold_uncertainty_score":0.80346334},"labels":[],"label_agreement":null},{"id":"W4366775072","doi":"10.3390/ph16040634","title":"Pharmacological Mechanism of Ketamine in Suicidal Behavior Based on Animal Models of Aggressiveness and Impulsivity: A Narrative Review","year":2023,"lang":"en","type":"review","venue":"Pharmaceuticals","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Impulsivity; Suicidal ideation; Serotonergic; Ketamine; Antidepressant; Endophenotype; Anhedonia; Mechanism (biology); Medicine; Psychology; Neuroinflammation; Bipolar disorder; Psychiatry; Clinical psychology; Lithium (medication); Poison control; Schizophrenia (object-oriented programming); Suicide prevention; Anxiety; Internal medicine; Cognition; Serotonin; Receptor; Inflammation","score_opus":0.24286204441277412,"score_gpt":0.4653622152532067,"score_spread":0.22250017084043258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366775072","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002126809,0.9936177,0.000030285797,0.00014040734,0.00013749134,0.0032856814,0.00038806954,0.0000634921,0.00021007431],"genre_scores_gemma":[0.025013683,0.97353005,0.000030413643,0.0006985502,0.000025688112,0.00060208846,0.000015540962,0.000060733437,0.00002323561],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9955821,0.0012999846,0.0011727461,0.0008719587,0.00058160134,0.0004915826],"domain_scores_gemma":[0.9967978,0.0019561567,0.00070566055,0.00027815808,0.00006040163,0.00020182614],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00078660646,0.0005647746,0.0026524772,0.0003932961,0.000050911505,0.000014002077,0.00051335164,0.00024747665,0.00021445748],"category_scores_gemma":[0.0007701073,0.00043445642,0.0004274936,0.0010876076,0.00040076664,0.000107451895,0.00024003597,0.0006793039,0.0000141927985],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064060045,0.0040236157,0.0000070153374,0.21444465,0.0001586811,0.0009505524,0.00027295158,0.000037128957,0.024507102,0.0058084354,0.00034900053,0.7488003],"study_design_scores_gemma":[0.023836967,0.007784161,0.000097331904,0.5119515,0.016112655,0.00046334657,0.0003321101,0.046126734,0.26677787,0.0056232708,0.11157281,0.009321222],"about_ca_topic_score_codex":0.0000045801276,"about_ca_topic_score_gemma":0.0000012212932,"teacher_disagreement_score":0.73947906,"about_ca_system_score_codex":0.000057964346,"about_ca_system_score_gemma":0.00021447755,"threshold_uncertainty_score":0.9998107},"labels":[],"label_agreement":null},{"id":"W4367396335","doi":"10.1016/j.jagp.2023.04.014","title":"Lipopolysaccharide, Immune Biomarkers and Cerebral Amyloid-Beta Deposition in Older Adults With Mild Cognitive Impairment &amp; Major Depressive Disorder","year":2023,"lang":"en","type":"article","venue":"American Journal of Geriatric Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Toronto Dementia Research Alliance; University Health Network; Baycrest Hospital; St. Michael's Hospital; Sunnybrook Health Science Centre; Sunnybrook Hospital","funders":"Canadian Institutes of Health Research; Health Canada; Centre for Addiction and Mental Health Foundation; Weston Family Foundation; Alzheimer's Drug Discovery Foundation; Alzheimer's Association","keywords":"Medicine; Internal medicine; Biomarker; Lipopolysaccharide binding protein; Immune system; Major depressive disorder; C-reactive protein; Acute-phase protein; Immunology; Endocrinology; Inflammation; Biology","score_opus":0.006025995756308318,"score_gpt":0.23990771173160177,"score_spread":0.23388171597529345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367396335","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99558157,0.0010118169,0.00032233848,0.001929426,0.0005383547,0.00044513997,0.000029349887,0.000051324463,0.000090699636],"genre_scores_gemma":[0.99792415,0.0005377723,0.0007957868,0.00049424067,0.00014144245,0.000024556555,0.000006544507,0.00004718938,0.000028316135],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99763834,0.00024766717,0.00065218983,0.00047759683,0.00045611465,0.0005280632],"domain_scores_gemma":[0.99842745,0.00022672798,0.0008571622,0.00019979595,0.00007315899,0.00021569259],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002192257,0.00031141125,0.0004748739,0.0007947625,0.00017560176,0.00007750486,0.0002884868,0.00006188828,0.00004125962],"category_scores_gemma":[0.00007257614,0.00025056518,0.00015589021,0.0018431139,0.0003341839,0.00035249774,0.00008263107,0.0003589952,0.000019359119],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019878311,0.0031298704,0.842198,0.00039828775,0.00064045953,0.00037644868,0.008014672,0.00014491906,0.017961642,0.00028168986,0.002843118,0.10413259],"study_design_scores_gemma":[0.014383609,0.001987891,0.9615639,0.0007317001,0.00013851796,0.0006136056,0.0152645,0.00010435954,0.004255676,0.00024065025,0.000019615312,0.00069596316],"about_ca_topic_score_codex":0.00033457478,"about_ca_topic_score_gemma":0.00022532015,"teacher_disagreement_score":0.11936592,"about_ca_system_score_codex":0.00004433563,"about_ca_system_score_gemma":0.0001834315,"threshold_uncertainty_score":0.99999464},"labels":[],"label_agreement":null},{"id":"W4367558985","doi":"10.5281/zenodo.7883947","title":"Microbial Energy Metabolism Fuels an Intestinal Macrophage Niche via Purinergic Signalling.","year":2023,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Niche; Energy metabolism; Purinergic receptor; Signalling; Macrophage; Cell biology; Metabolism; Chemistry; Bioenergetics; Ecology; Biology; Biochemistry; Adenosine; Mitochondrion","score_opus":0.040388690257119386,"score_gpt":0.2505563365457396,"score_spread":0.21016764628862022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367558985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8765539,0.00020996568,0.014333938,0.002046944,0.0008193542,0.00084397045,0.00043888763,0.008488657,0.096264414],"genre_scores_gemma":[0.99445647,0.00011378047,0.00014313156,0.00067709136,0.00026285413,9.3759745e-8,0.00050126563,0.0012212585,0.0026240582],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974069,0.00058257446,0.00028115572,0.0007027852,0.00042320197,0.00060338946],"domain_scores_gemma":[0.9989318,0.00005887568,0.000102828235,0.00044005798,0.00019132,0.0002751168],"candidate_categories":["sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00043596944,0.00021085452,0.00017585403,0.0003791744,0.0017057558,0.0007261573,0.0014361307,0.00007393077,0.008420355],"category_scores_gemma":[0.0008793733,0.00021830903,0.00008043805,0.0014804102,0.00026563043,0.00036023703,0.0010722089,0.00029390992,0.009838622],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007352537,0.00014393825,4.0541727e-7,0.000022116506,0.000008213818,0.00009430935,0.0004256294,0.00015406583,0.89444685,0.005012064,0.035748724,0.06387017],"study_design_scores_gemma":[0.0007175599,0.0002026667,0.0002512893,0.000013875691,0.000008535076,0.00021168905,0.000118334494,0.0020669254,0.21108246,0.0010791487,0.7839411,0.00030641814],"about_ca_topic_score_codex":0.0000228369,"about_ca_topic_score_gemma":6.8392353e-7,"teacher_disagreement_score":0.74819237,"about_ca_system_score_codex":0.00005100987,"about_ca_system_score_gemma":0.0000058323385,"threshold_uncertainty_score":0.9995939},"labels":[],"label_agreement":null},{"id":"W4367625035","doi":"10.1186/s12950-023-00340-3","title":"First trimester human umbilical cord perivascular cells (HUCPVC) modulate the kynurenine pathway and glutamate neurotransmission in an LPS-induced mouse model of neuroinflammation","year":2023,"lang":"en","type":"article","venue":"Journal of Inflammation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; CReATe Fertility Centre","funders":"Hospital for Sick Children","keywords":"Glutamatergic; Neuroprotection; Neuroinflammation; Neurotoxicity; Kynurenine pathway; Glutamate receptor; Pharmacology; Indoleamine 2,3-dioxygenase; Microglia; Kynurenine; Lipopolysaccharide; Medicine; Biology; Biochemistry; Receptor; Immunology; Inflammation; Internal medicine; Toxicity","score_opus":0.04612519532617023,"score_gpt":0.2749323025495519,"score_spread":0.22880710722338168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367625035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99833477,0.00000703796,0.00026827428,0.00089264376,0.00008648738,0.000344671,0.0000036296215,0.000035410445,0.00002705331],"genre_scores_gemma":[0.9996487,0.00009041606,0.00006564786,0.000042268308,0.00006487281,0.000005349436,0.000002478355,0.000025204776,0.000055072527],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979673,0.00029306993,0.0008245462,0.00022577925,0.0004785641,0.00021072454],"domain_scores_gemma":[0.9989095,0.00013938916,0.00050144986,0.00025987194,0.00009336943,0.00009642582],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064310554,0.00017037315,0.00026431927,0.00033312012,0.00015684485,0.00008756784,0.0002803264,0.000096383155,0.000008244485],"category_scores_gemma":[0.00022097299,0.00012370397,0.00011658575,0.000394966,0.000079005855,0.0007485334,0.00004655532,0.00029475763,0.0000040877667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017340377,0.000045083703,0.00007576473,0.00006200571,0.0000029337843,0.000013646228,0.0012739461,0.0557599,0.938119,0.00015256087,0.000008615139,0.0043131425],"study_design_scores_gemma":[0.0011363103,0.00034155647,0.009415844,0.000056421817,0.000008153604,0.000015458381,0.000062268715,0.24400404,0.7440063,0.0008281438,0.000020819563,0.00010472719],"about_ca_topic_score_codex":0.0000064225937,"about_ca_topic_score_gemma":0.00002040412,"teacher_disagreement_score":0.19411275,"about_ca_system_score_codex":0.000024674187,"about_ca_system_score_gemma":0.000052506846,"threshold_uncertainty_score":0.50445014},"labels":[],"label_agreement":null},{"id":"W4372174201","doi":"10.1101/2023.05.04.539419","title":"Ribosomal dysregulation: A conserved pathophysiological mechanism in human depression and mouse chronic stress","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Major depressive disorder; Pseudogene; Transcriptome; Mechanism (biology); Phenotype; Biology; Gene; Neuroscience; Psychology; Genetics; Gene expression; Mood; Clinical psychology","score_opus":0.029970670382484216,"score_gpt":0.24427373760939003,"score_spread":0.2143030672269058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4372174201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973905,0.00022913507,0.00015790825,0.00011337263,0.00041335027,0.0008177615,0.00023018163,0.00064409204,0.0000036679228],"genre_scores_gemma":[0.99882376,0.00019210675,0.00025559074,0.00016235324,0.0001985048,0.00024796728,7.477479e-7,0.000106257154,0.00001268373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99654806,0.00036974205,0.00051954,0.0015723245,0.00038086186,0.00060950423],"domain_scores_gemma":[0.9983576,0.00017186212,0.00030824705,0.0008811721,0.00007003104,0.00021110491],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027340167,0.0005288021,0.0005387047,0.0003062742,0.00025478314,0.0002123449,0.0005695125,0.00062762504,0.00003797566],"category_scores_gemma":[0.00038854947,0.0005280674,0.00011204704,0.0004581245,0.00025293726,0.00015218079,0.0010266259,0.00080255733,0.00003365313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030454199,0.00013006746,0.0024334127,0.00025809684,0.000008614925,0.00013727011,0.000011297625,0.00014762569,0.9948199,0.0019960182,0.000025825764,0.0000014419262],"study_design_scores_gemma":[0.0009355696,0.00006709092,0.17343909,0.00036076675,0.000010915818,1.746019e-8,0.0000039505207,0.0014009262,0.8230736,0.0001261469,0.000024557632,0.00055736065],"about_ca_topic_score_codex":0.00005207043,"about_ca_topic_score_gemma":0.000018777057,"teacher_disagreement_score":0.17174627,"about_ca_system_score_codex":0.00018265494,"about_ca_system_score_gemma":0.00022111934,"threshold_uncertainty_score":0.9997171},"labels":[],"label_agreement":null},{"id":"W4376116796","doi":"10.1017/s1092852923002316","title":"Associations between peripheral inflammation and clinical phenotypes of bipolar depression in a lower-middle income country","year":2023,"lang":"en","type":"article","venue":"CNS Spectrums","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Department of Psychiatry, University of Toronto; National Institutes of Health; University of Toronto; National Institute for Health and Care Research; Patient-Centered Outcomes Research Institute; H. Lundbeck A/S; Stanley Medical Research Institute; Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation; Fondation Brain Canada; Pfizer; Janssen Pharmaceuticals; King's College London; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Depression (economics); Medicine; Bipolar disorder; Internal medicine; Anhedonia; Bipolar II disorder; Inflammation; Clinical trial; Randomized controlled trial; C-reactive protein; Psychiatry; Schizophrenia (object-oriented programming)","score_opus":0.034395127782413,"score_gpt":0.3012060372390458,"score_spread":0.2668109094566328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376116796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984542,0.00007567549,0.000023597464,0.00027867116,0.00015926678,0.00015639387,0.00005282181,0.0000870201,0.0007123189],"genre_scores_gemma":[0.99949974,0.0001620166,0.0000453768,0.000045259545,0.0001189634,0.0000039019837,0.000016301256,0.000012365132,0.00009606114],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988801,0.00011720188,0.00035393678,0.00024977475,0.00019701841,0.0002019678],"domain_scores_gemma":[0.9992517,0.00040429484,0.00013042465,0.00015128638,0.000011716238,0.000050542876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029541485,0.000087975226,0.00020299094,0.00013738115,0.00008186513,0.000027802078,0.00013344172,0.000102845,0.000034867127],"category_scores_gemma":[0.0007738715,0.0000835942,0.000043390053,0.0006132824,0.00011606999,0.00020439661,0.00008177214,0.0001728289,0.00003213841],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024959794,0.000057513105,0.9702384,0.000021953705,0.0000071626396,0.000006564405,0.00038900677,0.000028498062,0.021663407,0.0019162997,0.000060047285,0.0055862223],"study_design_scores_gemma":[0.00058147905,0.000060957842,0.9855321,0.000037901806,0.000005237328,4.95115e-7,0.00004738053,0.0006224045,0.010323336,0.002205567,0.000483588,0.000099550845],"about_ca_topic_score_codex":0.00005672935,"about_ca_topic_score_gemma":0.0001769671,"teacher_disagreement_score":0.015293737,"about_ca_system_score_codex":0.000037687325,"about_ca_system_score_gemma":0.00003757608,"threshold_uncertainty_score":0.34088725},"labels":[],"label_agreement":null},{"id":"W4376121784","doi":"10.1007/s40520-023-02409-8","title":"Dementia, infections and vaccines: 30 years of controversy","year":2023,"lang":"en","type":"review","venue":"Aging Clinical and Experimental Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Università degli Studi di Palermo","keywords":"Dementia; Neuroinflammation; Medicine; Disease; Subclinical infection; Dysbiosis; Pathogenesis; Immunology; Intensive care medicine; Virology; Pathology","score_opus":0.3305689522106444,"score_gpt":0.5478801449819528,"score_spread":0.2173111927713084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376121784","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01276581,0.9857189,0.0000014652202,0.000040085153,0.00022000448,0.000522693,0.0000203842,0.000042424745,0.000668232],"genre_scores_gemma":[0.016272452,0.9830973,0.00000881223,0.00005132778,0.00010168378,0.00005702663,0.0000035346663,0.000030784115,0.0003770431],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975585,0.0005850032,0.00057746354,0.00057460257,0.00036014582,0.00034429287],"domain_scores_gemma":[0.9952119,0.0042737783,0.000102566686,0.0002209776,0.000023306684,0.00016745168],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009643799,0.00015896202,0.0007155165,0.00022336836,0.0001643745,0.000073931864,0.00021764256,0.00015594729,0.00010226308],"category_scores_gemma":[0.0017657616,0.00013685894,0.00018800989,0.00043686235,0.0006604362,0.00007045334,0.00056127115,0.0005771201,0.00013509858],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023012799,0.0005505777,0.00036194109,0.0034960916,0.00016809408,0.000055371755,0.00025235635,8.129289e-8,0.0005738391,0.0020202354,0.0031419282,0.98935646],"study_design_scores_gemma":[0.0013416259,0.00060385664,0.0003085668,0.0032755323,0.000070712485,0.000017678656,0.0004693949,0.000016556953,0.0005272345,0.00045446368,0.99258083,0.00033351925],"about_ca_topic_score_codex":0.000087212255,"about_ca_topic_score_gemma":0.000004639505,"teacher_disagreement_score":0.98943895,"about_ca_system_score_codex":0.0000152246785,"about_ca_system_score_gemma":0.00009433788,"threshold_uncertainty_score":0.55809456},"labels":[],"label_agreement":null},{"id":"W4376612756","doi":"10.1038/s41598-023-34363-w","title":"Behavioral and cellular responses to circadian disruption and prenatal immune activation in mice","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Centre hospitalier universitaire Sainte-Justine; Natural Sciences and Engineering Research Council of Canada; Velux Stiftung","keywords":"Circadian rhythm; Offspring; Prepulse inhibition; Dentate gyrus; Immune system; Autism; Neuroscience; Pregnancy; Microglia; Physiology; Autism spectrum disorder; Medicine; Schizophrenia (object-oriented programming); Endocrinology; Immunology; Biology; Internal medicine; Hippocampus; Psychiatry; Inflammation; Genetics","score_opus":0.03149703426229176,"score_gpt":0.2893255591317349,"score_spread":0.25782852486944313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376612756","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99835384,0.000021645646,0.000016941198,0.00029421155,0.00086732005,0.00028903867,0.0000024600058,0.0000700203,0.00008454498],"genre_scores_gemma":[0.9980048,0.0000031469042,0.000028145032,0.000030261835,0.000010720942,0.000018956234,0.000013872801,0.0000085974025,0.0018814892],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865055,0.000077961726,0.00021657949,0.0006046525,0.00023333459,0.00021691331],"domain_scores_gemma":[0.9995285,0.000068686066,0.00006986129,0.00023100225,0.000015108571,0.000086843764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074393034,0.00008014033,0.00008261874,0.00039513173,0.00019788055,0.00023009253,0.000057986323,0.00003967763,0.000013143848],"category_scores_gemma":[0.0005460558,0.00008034568,0.000017310467,0.00088854355,0.0001653638,0.00028863325,0.000088229885,0.00006775004,0.000016720609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024196772,0.000025685276,0.002427512,0.000010664087,2.6161604e-7,0.00014773071,0.0012030705,0.000004834962,0.9926201,0.000035925685,0.00016260287,0.0033374068],"study_design_scores_gemma":[0.00013389766,0.00003274276,0.10588809,0.00003759349,0.0000015978516,0.000047388083,0.00032014394,0.00008282777,0.89047074,0.0010215404,0.0018345595,0.00012887038],"about_ca_topic_score_codex":0.0000527471,"about_ca_topic_score_gemma":0.0000320815,"teacher_disagreement_score":0.10346058,"about_ca_system_score_codex":0.000021075084,"about_ca_system_score_gemma":0.000034719207,"threshold_uncertainty_score":0.32764018},"labels":[],"label_agreement":null},{"id":"W4376613134","doi":"10.1016/j.bbih.2023.100636","title":"Interaction between peripheral and central immune markers in clinical high risk for psychosis","year":2023,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Centre for Addiction and Mental Health; University of Toronto; McGill University; Douglas College","funders":"National Institutes of Health; Canada First Research Excellence Fund; Sächsische Aufbaubank; McGill University","keywords":"Translocator protein; Prodrome; Cohort; Schizophrenia (object-oriented programming); Medicine; Peripheral; Psychosis; Internal medicine; Dorsolateral prefrontal cortex; Proinflammatory cytokine; Psychology; Inflammation; Prefrontal cortex; Neuroinflammation; Immunology; Psychiatry; Cognition","score_opus":0.08111401945906732,"score_gpt":0.4005641742194559,"score_spread":0.31945015476038857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376613134","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99325305,0.00005766472,0.00007042595,0.004126741,0.00085202756,0.0012070134,0.0002086557,0.00019393329,0.000030498548],"genre_scores_gemma":[0.99726593,0.0007962231,0.00024850405,0.0011080846,0.000097147466,0.00015307555,0.00010123187,0.000044515575,0.00018530375],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99637306,0.0012397597,0.0008541573,0.000532254,0.00020797939,0.0007928017],"domain_scores_gemma":[0.9973807,0.001625197,0.00030329233,0.00042842692,0.000020812924,0.00024158374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014992356,0.00022930594,0.0004467776,0.00024648663,0.0004853409,0.00008108913,0.00032424822,0.0001613383,0.000055643093],"category_scores_gemma":[0.0010761853,0.00024204666,0.0001708371,0.00062539347,0.00022357775,0.00025524714,0.0001182806,0.0007908986,0.000018307548],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058479613,0.00072531967,0.48370206,0.00011460341,0.00001412833,0.000008800161,0.0020377059,0.000008331223,0.0043050004,0.00018670027,0.00515187,0.5031607],"study_design_scores_gemma":[0.0023886943,0.00055655825,0.9918204,0.00005385046,0.0000106478565,0.0000039718075,0.0010171784,0.00011916306,0.00035306983,0.00017181337,0.003282596,0.00022203874],"about_ca_topic_score_codex":0.0046709613,"about_ca_topic_score_gemma":0.0006633013,"teacher_disagreement_score":0.50811833,"about_ca_system_score_codex":0.00016106837,"about_ca_system_score_gemma":0.00012051282,"threshold_uncertainty_score":0.9870376},"labels":[],"label_agreement":null},{"id":"W4376642016","doi":"10.1016/j.jad.2023.05.014","title":"Does depression in mid-life predispose to greater cognitive decline in later life in the Whitehall II cohort?","year":2023,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"Medical Research Council; Dementias Platform UK; Elizabeth Blackwell Institute for Health Research, University of Bristol; National Institute for Health and Care Research; Alzheimer's Society; Wellcome Trust","keywords":"Depression (economics); Dementia; Verbal fluency test; Cognitive decline; Cohort; Psychology; Psychiatry; Late life depression; Cognition; Clinical psychology; Medicine; Disease; Internal medicine; Neuropsychology","score_opus":0.015073639007308341,"score_gpt":0.28248119818218365,"score_spread":0.2674075591748753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376642016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932394,0.000055979915,0.000029070055,0.005052354,0.00032823018,0.0008090655,0.000014334309,0.000019111852,0.00045242775],"genre_scores_gemma":[0.9959533,0.00016995751,0.000008208865,0.0036813098,0.000055220815,0.000056563385,0.0000021501658,0.000025946523,0.000047323858],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99747413,0.00065660215,0.0005283519,0.00038143146,0.00050479954,0.0004546568],"domain_scores_gemma":[0.9984316,0.001025693,0.00019909922,0.00015275266,0.000050241764,0.00014061933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00096425926,0.00023130632,0.00036942007,0.0008604524,0.00008967324,0.000057368863,0.0004321646,0.000105713574,0.000045247656],"category_scores_gemma":[0.0038513006,0.00012648162,0.00012310974,0.0016692895,0.00010944665,0.0003595544,0.00018301292,0.0005349176,0.000024514598],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009738157,0.00047109323,0.97940433,0.000021180389,0.000013055127,0.00014842152,0.00929177,0.00110197,0.004892997,0.000006678846,0.0004971847,0.0031775264],"study_design_scores_gemma":[0.0035134668,0.0003450726,0.98589027,0.00023210494,0.000008920886,0.000006144209,0.0039472096,0.00015245793,0.0046324255,0.0009260577,0.00015252944,0.00019334468],"about_ca_topic_score_codex":0.00011985652,"about_ca_topic_score_gemma":0.004720192,"teacher_disagreement_score":0.006485959,"about_ca_system_score_codex":0.000059121638,"about_ca_system_score_gemma":0.00008841779,"threshold_uncertainty_score":0.5157771},"labels":[],"label_agreement":null},{"id":"W4376642889","doi":"10.1371/journal.pone.0285123","title":"Multi-omic modeling of antidepressant response implicates dynamic immune and inflammatory changes in individuals who respond to treatment","year":2023,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Canada First Research Excellence Fund","keywords":"DNA methylation; Major depressive disorder; Genotyping; Antidepressant; Biomarker; Bioinformatics; Medicine; Computational biology; Phenotype; Oncology; Biology; Gene; Gene expression; Genetics; Genotype; Internal medicine; Psychiatry; Cognition","score_opus":0.06933299734609195,"score_gpt":0.28661629499133995,"score_spread":0.217283297645248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376642889","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976859,0.00020573889,0.0000075378643,0.0012739056,0.0000122082365,0.0006203483,0.00008095802,0.000098010736,0.000015378788],"genre_scores_gemma":[0.998393,0.00077347725,0.00028670108,0.00010862034,0.0000056392337,0.00012032596,0.0000036825256,0.000028536848,0.00028003554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857986,0.00020059505,0.00027577812,0.0004119483,0.00021540093,0.00031644647],"domain_scores_gemma":[0.99908507,0.00043186423,0.00007094098,0.00031868217,0.000018156683,0.000075303076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034806487,0.00015997817,0.0003179277,0.0005693534,0.00006305155,0.000026233785,0.00019318382,0.000063445994,0.000007945378],"category_scores_gemma":[0.0006207378,0.0001497926,0.000029798673,0.0005122224,0.00006780194,0.00008113357,0.00016851585,0.00007830669,0.00003038471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003828503,0.00035201872,0.0063362294,0.00004860123,0.000017876158,0.000012778762,0.0022281827,0.0004468904,0.98962003,0.000013562784,0.0000024664566,0.00053848897],"study_design_scores_gemma":[0.0013480484,0.00025874443,0.29815468,0.00024076692,0.0000129002165,0.0000013598489,0.00032574937,0.053604767,0.6457594,0.00009725918,0.0000111576255,0.00018513996],"about_ca_topic_score_codex":0.000043101743,"about_ca_topic_score_gemma":0.000111644804,"teacher_disagreement_score":0.34386063,"about_ca_system_score_codex":0.000047876067,"about_ca_system_score_gemma":0.000034792924,"threshold_uncertainty_score":0.61083645},"labels":[],"label_agreement":null},{"id":"W4377013213","doi":"10.1139/cjpp-2022-0535","title":"URB597 attenuates stress-induced ventricular structural remodeling by modulating cytokines, NF-κB, and JAK2/STAT3 pathways in female and male rats","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Endocrinology; Internal medicine; Ventricle; STAT3; Chronic stress; Biology; Medicine; Signal transduction; Chemistry; Cell biology","score_opus":0.031986942973207234,"score_gpt":0.27282784452672293,"score_spread":0.2408409015535157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377013213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980661,0.0008922977,0.0000017131167,0.00049873494,0.00033595852,0.000109353714,0.00006680308,0.0000076634615,0.00002134551],"genre_scores_gemma":[0.99892485,0.00024197607,0.000020610489,0.00067042705,0.00009988666,0.0000026803768,0.0000074138748,0.000011949724,0.00002018363],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877435,0.00021298937,0.00026652796,0.00027050872,0.000057139354,0.00041850092],"domain_scores_gemma":[0.99924475,0.00023120194,0.00014246906,0.000052238272,0.00003187404,0.00029748664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015287935,0.00014604598,0.00027367176,0.00025943422,0.00022521972,0.00002213648,0.00012292092,0.000109592365,0.00011271007],"category_scores_gemma":[0.000090952104,0.00013626441,0.000029205368,0.00023604289,0.00021479446,0.00014978989,0.00003740669,0.00033464952,0.0000017055263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003778658,0.0000058011265,0.005528718,0.000042167125,0.000011139461,0.00044913284,0.0005231313,0.0006113164,0.9908675,0.00005189863,0.00044688562,0.0014245473],"study_design_scores_gemma":[0.0028813,0.0003436158,0.040536575,0.000062740684,0.000035693447,0.0008518668,0.0008302176,0.01870056,0.9310653,0.0038987787,0.0003887803,0.00040456635],"about_ca_topic_score_codex":0.000301342,"about_ca_topic_score_gemma":0.00042017666,"teacher_disagreement_score":0.059802175,"about_ca_system_score_codex":0.000025806496,"about_ca_system_score_gemma":0.00013718766,"threshold_uncertainty_score":0.55567014},"labels":[],"label_agreement":null},{"id":"W4377232788","doi":"10.1097/jcp.0000000000001701","title":"Proposed Antidepressant-Associated Antimicrobial Resistance","year":2023,"lang":"en","type":"letter","venue":"Journal of Clinical Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McMaster University; Hamilton Health Sciences","funders":"","keywords":"Psychiatry; Medicine; Antidepressant; Family medicine; Gerontology; Library science; Psychology","score_opus":0.09068294622943249,"score_gpt":0.41917865097148144,"score_spread":0.3284957047420489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377232788","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.085103266,0.00018069499,0.000028765802,0.8707963,0.03889906,0.000645213,0.00016680532,0.00020099414,0.003978891],"genre_scores_gemma":[0.028960802,0.002639246,0.00013153067,0.9390446,0.014717684,0.000004716729,0.000013816108,0.0001842697,0.014303327],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9911759,0.0026209657,0.003559111,0.00086358405,0.0009011209,0.0008793376],"domain_scores_gemma":[0.98869413,0.0059861806,0.0043523754,0.00040750208,0.0003297827,0.0002300498],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0020858846,0.0005047445,0.0019219546,0.00049538765,0.00015606424,0.00008449214,0.0017800801,0.0019075419,0.0004953652],"category_scores_gemma":[0.0073671085,0.00042740352,0.0013453049,0.00073550205,0.0007962001,0.00019713423,0.00014091386,0.007913692,0.0004730518],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001432067,0.00041974394,0.00012341373,0.000119652854,0.0001923006,0.006226081,0.000021961816,0.0000045105758,0.01591788,0.0000051037046,0.9748888,0.00064851076],"study_design_scores_gemma":[0.009615396,0.00045616608,0.0013361508,0.00029496025,0.00017375333,0.000102263744,0.000004412877,0.000010093688,0.0033082222,0.0011316226,0.9830641,0.00050286646],"about_ca_topic_score_codex":0.0000017528647,"about_ca_topic_score_gemma":0.0000059244467,"teacher_disagreement_score":0.0682483,"about_ca_system_score_codex":0.00006412362,"about_ca_system_score_gemma":0.00056049274,"threshold_uncertainty_score":0.9998178},"labels":[],"label_agreement":null},{"id":"W4377287102","doi":"10.1038/s41467-023-38530-5","title":"Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes","year":2023,"lang":"en","type":"review","venue":"Nature Communications","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":136,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Douglas Mental Health University Institute","funders":"Medical Research Council; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Alliance de recherche numérique du Canada; National Alliance for Research on Schizophrenia and Depression; Government of Canada; Fondation Brain Canada; McGill University; Health Canada; Canada First Research Excellence Fund; Brain and Behavior Research Foundation","keywords":"Transcriptome; Biology; Cell type; Dorsolateral prefrontal cortex; Microglia; Major depressive disorder; Parvalbumin; Gene; Prefrontal cortex; Neuroscience; Gene expression; Genetics; Cell; Inflammation; Amygdala","score_opus":0.16595681228441914,"score_gpt":0.3517841420603815,"score_spread":0.18582732977596236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377287102","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.034580354,0.9635239,0.0000050264766,0.00018380086,0.00010273152,0.00060158095,0.0005522708,0.00009482398,0.00035547957],"genre_scores_gemma":[0.34114823,0.6583636,0.00007898843,0.000026946813,0.00003201185,0.00004656845,0.0001298292,0.000041328454,0.00013253224],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980821,0.00043931147,0.00042102666,0.000615275,0.00016101236,0.00028129097],"domain_scores_gemma":[0.99694145,0.0015489799,0.0002084484,0.0011806563,0.000023565543,0.00009689196],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013069634,0.00039107964,0.0007925938,0.00025887866,0.0002607577,0.00013025703,0.001379995,0.0005314493,0.000011540995],"category_scores_gemma":[0.000077545716,0.00030993196,0.00011546741,0.00048513556,0.00028620666,0.000086919994,0.00052630773,0.001231021,0.000025105075],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028363544,0.00054409116,0.11944315,0.018793708,0.00007502366,0.000028279745,0.00077667314,4.5834486e-7,0.003445938,0.00083211303,0.0016590861,0.8543731],"study_design_scores_gemma":[0.00042158406,0.00005118588,0.090496786,0.0035163984,0.00023606779,0.000014291573,0.00014529841,0.000020483374,0.00070773176,0.00031922414,0.9031246,0.0009463607],"about_ca_topic_score_codex":0.000016572754,"about_ca_topic_score_gemma":0.00030385813,"teacher_disagreement_score":0.9014655,"about_ca_system_score_codex":0.000026789034,"about_ca_system_score_gemma":0.000056875975,"threshold_uncertainty_score":0.99993527},"labels":[],"label_agreement":null},{"id":"W4377564379","doi":"10.1017/s109285292300233x","title":"Pro-inflammatory markers are associated with response to sequential pharmacotherapy in major depressive disorder: a CAN-BIND-1 report","year":2023,"lang":"en","type":"article","venue":"CNS Spectrums","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Douglas College; University of Calgary; University of British Columbia; St. Joseph’s Healthcare Hamilton; Queen's University; McMaster University; University of Toronto; Centre for Addiction and Mental Health","funders":"Ontario Brain Institute","keywords":"Pharmacotherapy; Major depressive disorder; Medicine; Pharmacology; Internal medicine; Psychiatry; Mood","score_opus":0.018953600625548708,"score_gpt":0.2774812576349771,"score_spread":0.2585276570094284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377564379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921206,0.000023773273,0.0000413619,0.005114136,0.00026255383,0.0011363843,0.00006406428,0.00048788934,0.00074923463],"genre_scores_gemma":[0.99440354,0.000024278368,0.000016892262,0.0011746417,0.00005513093,0.00025715106,0.000014095,0.00008223656,0.0039720344],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9971133,0.00039819462,0.00036468657,0.0008333551,0.00052808423,0.0007623964],"domain_scores_gemma":[0.99870014,0.00039297735,0.00023631848,0.00043968722,0.000031168147,0.00019971262],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004995187,0.00029882486,0.00029732162,0.00047139134,0.00020662036,0.00008741144,0.00039383996,0.00010441818,0.0002091968],"category_scores_gemma":[0.001357997,0.00027155902,0.000089613066,0.0017470513,0.00015591373,0.00017840622,0.00009151924,0.00030881783,0.00011619185],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0073574116,0.0003634438,0.121995986,0.00004106559,0.00008092742,0.015238882,0.0022895131,0.0015313003,0.8447406,0.00013493175,0.0052520516,0.00097386324],"study_design_scores_gemma":[0.009738233,0.00048486658,0.5460154,0.00030017426,0.000027081722,0.00016513174,0.0012404593,0.0011054781,0.42998624,0.00050351,0.009201819,0.0012316102],"about_ca_topic_score_codex":0.000088700974,"about_ca_topic_score_gemma":0.0017174863,"teacher_disagreement_score":0.42401943,"about_ca_system_score_codex":0.0002392391,"about_ca_system_score_gemma":0.00028805184,"threshold_uncertainty_score":0.99997365},"labels":[],"label_agreement":null},{"id":"W4378171864","doi":"10.1007/s40265-023-01872-x","title":"New Pharmacologic Approaches to the Treatment of Bipolar Depression","year":2023,"lang":"en","type":"review","venue":"Drugs","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of Ottawa; Université de Montréal; McGill University; University of British Columbia","funders":"","keywords":"Lurasidone; Bipolar disorder; Medicine; Randomized controlled trial; Antidepressant; Mood; Atypical depression; Mood disorders; Psychiatry; Schizophrenia (object-oriented programming); Internal medicine; Anxiety; Antipsychotic","score_opus":0.30201206338410325,"score_gpt":0.36725527057051566,"score_spread":0.06524320718641241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378171864","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000033159187,0.9973039,0.000018355606,0.00014412738,0.00035045078,0.0012146471,0.000047520996,0.00009387063,0.0007939627],"genre_scores_gemma":[0.000025324674,0.99550414,0.000045628494,0.00011653086,0.00016393504,0.00016815256,0.000008285356,0.00003740542,0.0039306227],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99864185,0.0002148339,0.0002657652,0.00043755525,0.00020775943,0.00023223858],"domain_scores_gemma":[0.99893516,0.00045238345,0.00015380829,0.00035978836,0.0000033542847,0.00009548379],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008096076,0.0002629857,0.0006158852,0.00012442916,0.00008504193,0.00002452402,0.0005327182,0.00010134618,0.000072852396],"category_scores_gemma":[0.000059639737,0.00013185854,0.00034470123,0.0006576496,0.0000387577,0.00002433482,0.000087702705,0.0001019079,0.00064919604],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000034354816,0.00007643009,3.607708e-7,0.0006726432,0.000016127142,0.00000343921,0.00043481257,0.000003539838,0.000023743589,0.00007844311,0.0036414494,0.9950456],"study_design_scores_gemma":[0.00014935173,0.00007119568,0.0000015950518,0.00045097555,0.00010565764,0.0000023187067,0.000034778237,0.000004958877,0.0011366244,0.00003706401,0.99787146,0.00013402561],"about_ca_topic_score_codex":0.000028813616,"about_ca_topic_score_gemma":0.0000035061266,"teacher_disagreement_score":0.99491155,"about_ca_system_score_codex":0.00005004955,"about_ca_system_score_gemma":0.00012161425,"threshold_uncertainty_score":0.8344318},"labels":[],"label_agreement":null},{"id":"W4378174769","doi":"10.3390/brainsci13060852","title":"Indoleamine 2,3-Dioxygenase as a Therapeutic Target for Alzheimer’s Disease and Geriatric Depression","year":2023,"lang":"en","type":"review","venue":"Brain Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Krembil Foundation","keywords":"Indoleamine 2,3-dioxygenase; Neuroinflammation; Kynurenine; Kynurenine pathway; Multiple sclerosis; Dementia; Depression (economics); Medicine; Downregulation and upregulation; Alzheimer's disease; Central nervous system; Regulator; Disease; Microglia; Inflammation; Neuroscience; Immunology; Psychology; Internal medicine; Biology; Tryptophan","score_opus":0.16041267460074174,"score_gpt":0.3968096550026318,"score_spread":0.23639698040189008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378174769","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017956087,0.9962906,0.00005802371,0.000311289,0.00039144486,0.0020269514,0.00016330226,0.0002051314,0.00037366257],"genre_scores_gemma":[0.00032066574,0.9967927,0.00017310934,0.000960139,0.00021928646,0.0005145113,0.00001564061,0.000067502086,0.00093645684],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966471,0.00033399396,0.00046937284,0.001365857,0.00055195775,0.00063171604],"domain_scores_gemma":[0.99620664,0.002748779,0.0003347718,0.0003692483,0.0000205822,0.00031995834],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007554483,0.00047093994,0.00081396283,0.00051493256,0.0006391105,0.00031159518,0.00096971,0.00015956105,0.00005693772],"category_scores_gemma":[0.0022749866,0.0003258215,0.0003385513,0.0017139341,0.0006810358,0.00024756865,0.00026058735,0.00018597327,0.00013197698],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022684519,0.00006843572,0.0000027861736,0.0024973946,0.000025187328,0.000028828956,0.00006109368,0.0000031152067,0.00010393963,0.001371775,0.0028379776,0.9929768],"study_design_scores_gemma":[0.0003690835,0.0001714212,0.00004068613,0.00148852,0.00012175631,0.000025432817,0.00004084526,0.00015445295,0.00018267486,0.0056263157,0.99116296,0.0006158412],"about_ca_topic_score_codex":0.000008145311,"about_ca_topic_score_gemma":0.0000027103065,"teacher_disagreement_score":0.99236095,"about_ca_system_score_codex":0.000017760154,"about_ca_system_score_gemma":0.0005999173,"threshold_uncertainty_score":0.99991935},"labels":[],"label_agreement":null},{"id":"W4378190875","doi":"10.1016/j.brainres.2023.148423","title":"Putative pathological mechanisms of late-life depression and Alzheimer’s disease","year":2023,"lang":"en","type":"review","venue":"Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Institute of Neurosciences, Mental Health and Addiction; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Pathological; Depression (economics); Neuroscience; Disease; Alzheimer's disease; Late life depression; Psychology; Medicine; Pathology; Cognition","score_opus":0.3833675220234992,"score_gpt":0.4810390472408491,"score_spread":0.0976715252173499,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378190875","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014979813,0.9964358,0.00007687327,0.00032867785,0.00009683864,0.0017008283,0.00029526997,0.00012470379,0.00079121324],"genre_scores_gemma":[0.0011234658,0.9973368,0.000068217436,0.00017159087,0.000043532753,0.00028490063,0.000033387885,0.00007828706,0.00085980206],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99413484,0.002576683,0.0004859888,0.0010491841,0.0010981872,0.0006551026],"domain_scores_gemma":[0.99278826,0.005996734,0.00017117447,0.00048086492,0.00007391053,0.00048903434],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0016288332,0.00032144564,0.00093971007,0.0005484124,0.00024400358,0.00008224499,0.00070824637,0.0002956599,0.00010499545],"category_scores_gemma":[0.012102299,0.00022737177,0.00025052106,0.0012514961,0.0007327718,0.000082087005,0.0009907669,0.00088613946,0.00026823868],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095686584,0.00024004112,0.0000039138677,0.009113287,0.000053433007,0.0008487893,0.00017947947,0.0000021527135,0.00058453047,0.019829167,0.0041837133,0.9648658],"study_design_scores_gemma":[0.0019071667,0.000872759,0.0008482021,0.020780973,0.00036828243,0.00006029571,0.0004987496,0.0003534445,0.0018047767,0.15131982,0.8190967,0.0020888587],"about_ca_topic_score_codex":0.000009204519,"about_ca_topic_score_gemma":0.0000012832172,"teacher_disagreement_score":0.96277696,"about_ca_system_score_codex":0.000023384717,"about_ca_system_score_gemma":0.00045038576,"threshold_uncertainty_score":0.99621916},"labels":[],"label_agreement":null},{"id":"W4378781930","doi":"10.1001/jamapsychiatry.2023.1321","title":"Neuroinflammation After COVID-19 With Persistent Depressive and Cognitive Symptoms","year":2023,"lang":"en","type":"letter","venue":"JAMA Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":144,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McMaster University; University of British Columbia; McGill University; Hamilton Health Sciences; University of Toronto; BC Mental Health & Substance Use Services; Waypoint Centre for Mental Health Care; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Coronavirus disease 2019 (COVID-19); Neuroinflammation; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Cognition; Depressive symptoms; Medicine; Psychology; Depression (economics); Psychiatry; Clinical psychology; Internal medicine; Virology; Inflammation","score_opus":0.018081200954171664,"score_gpt":0.2533662371573519,"score_spread":0.23528503620318025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378781930","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16244976,0.0004943747,0.000111398665,0.8312551,0.0016926012,0.001101025,0.000398841,0.0004689903,0.00202792],"genre_scores_gemma":[0.055841397,0.000081404956,0.000048673828,0.93883276,0.0022085821,0.00026409625,0.00012329138,0.0001505468,0.0024492359],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99727666,0.00024865798,0.00027644384,0.0011183652,0.0005747201,0.0005051349],"domain_scores_gemma":[0.9985628,0.00056128885,0.0002719352,0.000367648,0.000044170523,0.000192127],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006993935,0.00046131824,0.00031984568,0.0002920316,0.00023646299,0.00030075683,0.0002822399,0.0005526243,0.0001269475],"category_scores_gemma":[0.0004378951,0.00038643967,0.00017817235,0.0003606441,0.00035904985,0.00023483075,0.00012030602,0.0013256555,0.00022096357],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059845415,0.000054086446,0.0031924553,0.0008794427,0.00010969649,0.0014614714,0.00078541355,0.000014456299,0.0001284996,0.00007613407,0.99098015,0.001719714],"study_design_scores_gemma":[0.019538127,0.002309857,0.041220356,0.0024799416,0.0012484054,0.00201033,0.0023763685,0.0005926603,0.0007650534,0.004440483,0.91800225,0.0050161723],"about_ca_topic_score_codex":0.00001968037,"about_ca_topic_score_gemma":0.00004421903,"teacher_disagreement_score":0.10757768,"about_ca_system_score_codex":0.000043182383,"about_ca_system_score_gemma":0.00029272286,"threshold_uncertainty_score":0.99985874},"labels":[],"label_agreement":null},{"id":"W4378782280","doi":"10.1503/jpn.220218","title":"Barrier–environment interactions along the gut–brain axis and their influence on cognition and behaviour throughout the lifespan","year":2023,"lang":"en","type":"review","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund; Fondation Brain Canada","keywords":"Context (archaeology); Environmental enrichment; Cognition; Neuroscience; Psychology; Blood–brain barrier; Gut flora; Environmental stress; Biology; Developmental psychology; Ecology; Central nervous system; Immunology","score_opus":0.05449792898778476,"score_gpt":0.34168070981735593,"score_spread":0.28718278082957116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378782280","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.104949065,0.8728779,0.0000967472,0.01608161,0.004018461,0.0015228138,0.00021236666,0.00006006208,0.00018099199],"genre_scores_gemma":[0.03920994,0.9568501,0.0000142591925,0.0035401667,0.00019401811,0.000020612662,5.2229603e-7,0.000030309086,0.00014006629],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976386,0.00053342566,0.00062268326,0.00052891223,0.00038426288,0.00029215144],"domain_scores_gemma":[0.9973221,0.0014276857,0.00075309427,0.00031148444,0.000018093158,0.00016756976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006711066,0.00036173512,0.00050096615,0.00017816079,0.00095614314,0.0003331049,0.0005893102,0.00009049074,0.000008145755],"category_scores_gemma":[0.0007514206,0.00017671536,0.00019497829,0.0004343557,0.0010560687,0.00040056638,0.00020816899,0.001019031,0.0000065585155],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003650332,0.0016781095,0.0026078755,0.007258385,0.00016961648,0.0002791792,0.006495447,0.00016325145,0.022564119,0.010176488,0.009559843,0.9386827],"study_design_scores_gemma":[0.0012146584,0.0022350424,0.02566572,0.0103582945,0.00056388404,0.007242478,0.002202817,0.00012872998,0.0004377125,0.005195711,0.94348717,0.0012677991],"about_ca_topic_score_codex":0.000004473027,"about_ca_topic_score_gemma":0.0000139245985,"teacher_disagreement_score":0.9374149,"about_ca_system_score_codex":0.000016498841,"about_ca_system_score_gemma":0.00013964208,"threshold_uncertainty_score":0.73539764},"labels":[],"label_agreement":null},{"id":"W4378803826","doi":"10.20944/preprints202305.2226.v1","title":"Analysis of the Circulating Metabolome of Patients with Cutaneous, Mucosal and Uveal Melanoma Reveals Distinct Metabolic Profiles with Implications for Response to Immunotherapy","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Princess Margaret Cancer Centre; Jewish General Hospital; University Health Network; University of Toronto; McGill University","funders":"Association Neurofibromatoses et Recklinghause","keywords":"Metabolome; Metabolomics; Melanoma; Kynurenine; Sphingolipid; Kynurenic acid; Kynurenine pathway; Biology; Cancer research; Ceramide; Sphingomyelin; Internal medicine; Medicine; Pharmacology; Tryptophan; Biochemistry; Bioinformatics; Apoptosis; Cholesterol; Amino acid","score_opus":0.07276503796081206,"score_gpt":0.3258689086929065,"score_spread":0.25310387073209445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378803826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949483,0.000044347318,0.0004139468,0.00049068563,0.00006204017,0.0025358298,0.0013812601,0.000073886185,0.000049673577],"genre_scores_gemma":[0.9984691,0.0000215217,0.000541087,0.00007913807,0.000012235924,0.000595311,0.000041440304,0.00006373222,0.00017642691],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99714494,0.00043416742,0.00064786436,0.0010463772,0.00040274064,0.00032389825],"domain_scores_gemma":[0.99639267,0.0009324311,0.000833127,0.0015025024,0.00024927748,0.00009000161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005608275,0.0003443005,0.00084957056,0.00043522974,0.00018276804,0.000023898005,0.0008113476,0.00012368312,0.000028092576],"category_scores_gemma":[0.0014536591,0.00023157343,0.0002676238,0.0013493529,0.00030090957,0.00005758022,0.00073876063,0.000248717,0.0000037055734],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013389441,0.00013879735,0.82962036,0.000095962656,0.00057997013,5.5041073e-7,0.0008944431,0.00092206366,0.16575976,0.00031012588,0.0000015468474,0.00033746223],"study_design_scores_gemma":[0.0005719317,0.00007489867,0.9517104,0.00006971208,0.000508482,0.0000021278356,0.000057456076,0.00007203378,0.04615565,0.0004479993,0.000076303564,0.0002530124],"about_ca_topic_score_codex":0.000100310644,"about_ca_topic_score_gemma":0.00006524252,"teacher_disagreement_score":0.12209002,"about_ca_system_score_codex":0.00003274508,"about_ca_system_score_gemma":0.00016210992,"threshold_uncertainty_score":0.944329},"labels":[],"label_agreement":null},{"id":"W4378835148","doi":"10.20944/preprints202305.1990.v1","title":"The Central Role of the Kynurenine Pathway of Tryptophan Metabolism in the Pathophysiology of Frailty, Sarcopenia and Osteoporosis","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Sarcopenia; Kynurenine; Osteoporosis; Medicine; Anabolism; Internal medicine; Kynurenine pathway; Niacin; Endocrinology; Catabolism; Tryptophan; Metabolism; Biology; Amino acid; Biochemistry","score_opus":0.0798588093477227,"score_gpt":0.30774385742768223,"score_spread":0.22788504807995952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378835148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996097,0.00063534186,0.000001844225,0.0008335964,0.0004949521,0.0009964248,0.00016638027,0.000026956952,0.00074749504],"genre_scores_gemma":[0.99848765,0.0009662585,0.000018788473,0.00015366067,0.000049797585,0.00010580889,0.0000048862616,0.000033745782,0.00017942172],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99636436,0.0010636416,0.0008340936,0.00076192996,0.0005314373,0.00044452786],"domain_scores_gemma":[0.9964844,0.0009037716,0.00078878267,0.0017005124,0.00006971214,0.00005280561],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082118355,0.00032719143,0.0006417709,0.00010464691,0.00013381067,0.000015879532,0.002257983,0.00025382117,0.00006732995],"category_scores_gemma":[0.001454269,0.00018001122,0.00032063763,0.0004777647,0.0010125514,0.000052941807,0.0028125565,0.00077097956,0.00001498712],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012985474,0.00017931536,0.038767632,0.00013243771,0.000028834793,0.0000020412008,0.006481614,0.00016662871,0.9486462,0.0031977063,0.000020772166,0.0022469626],"study_design_scores_gemma":[0.00032353005,0.000016076609,0.5152386,0.00006244263,0.000016101212,0.0000013439992,0.00068470696,0.00003126041,0.46628958,0.01689534,0.00033825287,0.00010278644],"about_ca_topic_score_codex":0.00060545356,"about_ca_topic_score_gemma":0.00023509272,"teacher_disagreement_score":0.4823566,"about_ca_system_score_codex":0.000017370112,"about_ca_system_score_gemma":0.00017355732,"threshold_uncertainty_score":0.73406446},"labels":[],"label_agreement":null},{"id":"W4379053264","doi":"10.1038/s41398-023-02438-x","title":"Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study","year":2023,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; H. Lundbeck A/S; Rijksuniversiteit Groningen; University of Glasgow; South London and Maudsley NHS Foundation Trust; University of Oxford; King's College London; University of Southampton; National Institute for Health and Care Research; Wellcome Trust; GlaxoSmithKline; University of Toronto; European Federation of Pharmaceutical Industries and Associations; Innovative Medicines Initiative; Wellcome; NIHR Cambridge Biomedical Research Centre; European Commission; Pfizer","keywords":"Inflammation; Major depressive disorder; Immune system; C-reactive protein; Immunology; Internal medicine; Gene expression; Tumor necrosis factor alpha; Medicine; Gene; Biology; Genetics","score_opus":0.04562863706974829,"score_gpt":0.2931822316908154,"score_spread":0.24755359462106713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379053264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99253845,0.0004462695,0.000039563314,0.0042534918,0.00086727756,0.00051683764,0.0004667563,0.00009014082,0.0007811945],"genre_scores_gemma":[0.999068,0.000018814826,0.00021638712,0.00030128573,0.000060815673,0.000018954284,0.000050176004,0.000022808968,0.00024273711],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99772716,0.00024340053,0.00065046723,0.00052383216,0.00063416705,0.00022096549],"domain_scores_gemma":[0.9989472,0.0004271068,0.0001645903,0.00040199445,0.0000181947,0.00004090215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030633248,0.00017204932,0.0001770709,0.00014462347,0.00014854668,0.000022387394,0.00042630613,0.00012581513,0.00034855658],"category_scores_gemma":[0.000048121536,0.00012360053,0.00010774509,0.0007820648,0.00007404112,0.00014421932,0.000049538525,0.00026826584,0.00009922855],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015140609,0.0015205526,0.20262608,0.000020587608,0.000046214696,0.000012537051,0.009671206,0.0016539723,0.77653974,0.0005224086,0.0034532787,0.0024193653],"study_design_scores_gemma":[0.005256333,0.00003968533,0.9268154,0.00007107603,0.000009475722,6.742337e-7,0.0004067748,0.00027919427,0.05840232,0.008442913,0.00012267465,0.00015348213],"about_ca_topic_score_codex":0.0001244219,"about_ca_topic_score_gemma":0.00009990215,"teacher_disagreement_score":0.72418934,"about_ca_system_score_codex":0.000008437905,"about_ca_system_score_gemma":0.00007107015,"threshold_uncertainty_score":0.5040284},"labels":[],"label_agreement":null},{"id":"W4379232822","doi":"10.3389/fpsyt.2023.1195012","title":"Exploring brain glutathione and peripheral blood markers in posttraumatic stress disorder: a combined [1H]MRS and peripheral blood study","year":2023,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Parkwood Institute; Lawson Health Research Institute; St Joseph's Health Care; Defence Research and Development Canada; University of Toronto; Western University; Centre for Addiction and Mental Health","funders":"Ministère de la Défense Nationale; Canadian Institute for Military and Veteran Health Research; Centre for Addiction and Mental Health","keywords":"Glutathione; Oxidative stress; Anterior cingulate cortex; Dorsolateral prefrontal cortex; Internal medicine; Myeloperoxidase; Peripheral; Medicine; Posttraumatic stress; Prefrontal cortex; Psychology; Endocrinology; Psychiatry; Inflammation; Chemistry; Cognition; Biochemistry","score_opus":0.026570551070347136,"score_gpt":0.2509513617860306,"score_spread":0.22438081071568347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379232822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928421,0.0009161558,0.000046722587,0.0017623532,0.002967851,0.0010355202,0.000027376782,0.00019382995,0.00020809617],"genre_scores_gemma":[0.99746656,0.00056027196,0.0010107937,0.00045882078,0.000053150776,0.00020247661,0.0000072352573,0.00006800975,0.00017269036],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99706846,0.0003842921,0.0005321047,0.0009207886,0.00037425634,0.0007201015],"domain_scores_gemma":[0.99922043,0.00012790134,0.00010699514,0.00036508316,0.000010521105,0.00016909491],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003859609,0.00039398065,0.00049306446,0.00051770714,0.00023644441,0.00015722503,0.00034258058,0.00010497287,0.000027210766],"category_scores_gemma":[0.00020163038,0.00041258163,0.00007037001,0.0011244729,0.00026101177,0.0005025633,0.00017323224,0.000451582,0.0000024222052],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004272914,0.0022387106,0.9752626,0.0002520276,0.00006626089,0.00013841459,0.013307054,0.00019056395,0.0006302382,0.00025268373,0.0016886052,0.0055455933],"study_design_scores_gemma":[0.017396886,0.001488128,0.8817298,0.0002981821,0.000057454792,0.000031390005,0.09072875,0.0047668223,0.00010151751,0.0024193833,0.00008799758,0.0008936937],"about_ca_topic_score_codex":0.00014614037,"about_ca_topic_score_gemma":0.00072965334,"teacher_disagreement_score":0.09353276,"about_ca_system_score_codex":0.000033655037,"about_ca_system_score_gemma":0.00006535697,"threshold_uncertainty_score":0.99983263},"labels":[],"label_agreement":null},{"id":"W4379511338","doi":"10.1136/annrheumdis-2023-eular.1459","title":"POS0130 INFLAMMATORY ACTIVITY IS ASSOCIATED WITH COGNITIVE IMPAIRMENT IN PATIENTS WITH RHEUMATOID ARTHRITIS","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Montreal Cognitive Assessment; Stroop effect; Trail Making Test; Internal medicine; Hospital Anxiety and Depression Scale; Rheumatoid arthritis; Physical therapy; Cohort; Prospective cohort study; Anxiety; Cognition; Dementia; Psychiatry; Disease; Cognitive impairment","score_opus":0.021742210795306683,"score_gpt":0.25385448233631663,"score_spread":0.23211227154100994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379511338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998208,0.000048725742,0.0000014692038,0.0005057602,0.000043674787,0.0006748726,0.0002952496,0.00009315207,0.0001290892],"genre_scores_gemma":[0.99907804,0.00027263942,0.0000010719652,0.0004945601,0.0000018984697,0.000059619426,0.000010445334,0.000025857647,0.000055879842],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99817723,0.00023424886,0.0002635991,0.00030270757,0.0006438027,0.00037840093],"domain_scores_gemma":[0.9986703,0.00054002245,0.000308684,0.00028594726,0.00009171345,0.000103356375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013337142,0.00020376004,0.00030896848,0.00013846775,0.00012855529,0.000039049213,0.00028246501,0.0000378486,0.000066656066],"category_scores_gemma":[0.0010285422,0.00012982175,0.00009869848,0.00083111,0.00029716565,0.0002690023,0.000114980416,0.000101145466,0.000035764424],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021549875,0.0044544875,0.9427789,0.00030767507,0.00029559922,0.00003832311,0.004166773,0.00022492479,0.0001415311,0.0002084936,0.005930891,0.03929743],"study_design_scores_gemma":[0.0025489833,0.00027274346,0.9891028,0.0021024838,0.0000070028345,5.5272517e-7,0.00027778058,0.00011283682,0.004849441,0.0005255216,0.000005288512,0.00019459713],"about_ca_topic_score_codex":0.000031559768,"about_ca_topic_score_gemma":0.00004604219,"teacher_disagreement_score":0.046323884,"about_ca_system_score_codex":0.000018587385,"about_ca_system_score_gemma":0.00011907813,"threshold_uncertainty_score":0.5293977},"labels":[],"label_agreement":null},{"id":"W4379615839","doi":"10.47626/2237-6089-2023-0677","title":"Evaluation of inflammatory markers in major psychiatric disorders: challenges and perspectives","year":2023,"lang":"en","type":"letter","venue":"Trends in Psychiatry and Psychotherapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Inflammation; Psychiatry; Medicine; Psychology; Immunology","score_opus":0.052992922221765174,"score_gpt":0.3187499491943531,"score_spread":0.26575702697258796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379615839","genre_codex":"commentary","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21608056,0.1360642,0.000004682422,0.6244178,0.0041916785,0.0012024287,0.00008795964,0.00018268416,0.017768003],"genre_scores_gemma":[0.16129975,0.7374801,0.00059494434,0.09360743,0.0034396208,0.000838731,0.00006764311,0.0005997799,0.0020720165],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9960484,0.0009172807,0.000600065,0.0011794828,0.0007777164,0.0004770645],"domain_scores_gemma":[0.9988455,0.0002683717,0.00030777528,0.00049403013,0.000030938143,0.000053372492],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001102271,0.00049861835,0.0005304536,0.0020666847,0.0000667959,0.00003529555,0.00033026558,0.00065072917,0.0002097553],"category_scores_gemma":[0.00003015644,0.00049153244,0.00013670721,0.0010380087,0.0003337615,0.00017137562,0.000012959582,0.0010537568,0.0000060805774],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072319916,0.00078463793,0.004952192,0.0008495547,0.000133824,0.000013898115,0.013111614,0.000014743613,0.00014345754,0.004512722,0.16537754,0.8093826],"study_design_scores_gemma":[0.023235884,0.0012787025,0.46736455,0.0011283334,0.00017833359,0.000032687694,0.006216069,0.0005558125,0.000028275967,0.41584855,0.08156869,0.0025641003],"about_ca_topic_score_codex":0.00002597469,"about_ca_topic_score_gemma":0.0015492367,"teacher_disagreement_score":0.8068185,"about_ca_system_score_codex":0.00003638187,"about_ca_system_score_gemma":0.00009604674,"threshold_uncertainty_score":0.99975365},"labels":[],"label_agreement":null},{"id":"W4379798883","doi":"10.1136/annrheumdis-2023-eular.2813","title":"POS1109 PUTATIVE ROLE OF THE HISTIDINE AND TRYPTOPHAN BIOCHEMICAL PATHWAYS IN THE MODE OF ACTION OF UPADACITINIB IN PATIENTS WITH ANKYLOSING SPONDYLITIS","year":2023,"lang":"en","type":"article","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"Medac; Celgene; Gilead Sciences; Chugai Pharmaceutical; Amgen; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; Sun Pharma; Biogen; GlaxoSmithKline","keywords":"Ankylosing spondylitis; Medicine; Mode of action; Tryptophan; Spondylitis; Pharmacology; Immunology; Biochemistry; Amino acid; Chemistry","score_opus":0.020236815583960736,"score_gpt":0.24991729656433695,"score_spread":0.22968048098037622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379798883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989672,0.000009617072,0.000008512442,0.00009255213,0.00001517346,0.00024773227,0.00016093897,0.000008652136,0.00048965093],"genre_scores_gemma":[0.99986374,0.000007083049,0.00004223286,0.0000505223,0.0000027138879,0.0000058562764,0.000009367351,0.0000061695823,0.00001230432],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913234,0.00011548736,0.000214634,0.00016966314,0.00024052519,0.00012735602],"domain_scores_gemma":[0.9994845,0.00023224084,0.00011164427,0.00013304393,0.000024165067,0.000014430335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008475858,0.0000786913,0.00013862328,0.000106078856,0.00002246978,0.000004799921,0.0001452955,0.000035438847,0.000013404925],"category_scores_gemma":[0.00021220419,0.00004436145,0.00002621335,0.0007335504,0.00021744122,0.000078696095,0.000046846762,0.00008602061,2.984177e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033575113,0.00025253886,0.029297473,0.000048163758,0.0000025086533,0.0000010996864,0.0043967552,0.000070295064,0.96102357,0.002268529,0.000019062758,0.0022842358],"study_design_scores_gemma":[0.00088704284,0.00011790441,0.23252751,0.00004253414,0.0000019548052,7.016762e-7,0.0019644136,0.00067854434,0.762182,0.0015396222,0.000009408362,0.00004836136],"about_ca_topic_score_codex":0.00013497719,"about_ca_topic_score_gemma":0.000038090486,"teacher_disagreement_score":0.20323004,"about_ca_system_score_codex":0.000013596804,"about_ca_system_score_gemma":0.000024216157,"threshold_uncertainty_score":0.18090075},"labels":[],"label_agreement":null},{"id":"W4381380386","doi":"10.9734/jammr/2023/v35i165087","title":"Psychosocial Factors, Pro-Inflammatory Markers &amp; Serum Lipids among Patients with Suicidal Ideation &amp; Suicidal Attempts","year":2023,"lang":"en","type":"article","venue":"Journal of Advances in Medicine and Medical Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Suicidal ideation; Impulsivity; Clinical psychology; Psychiatry; Eysenck Personality Questionnaire; Psychosocial; Hamilton Anxiety Rating Scale; Barratt Impulsiveness Scale; Psychology; Anxiety; Mini-international neuropsychiatric interview; Suicide attempt; Psychoticism; Personality; Poison control; Suicide prevention; Medicine; Big Five personality traits; Extraversion and introversion; Medical emergency","score_opus":0.06458851409334865,"score_gpt":0.4068496604434833,"score_spread":0.34226114635013466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381380386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937117,0.00036564242,0.00008186981,0.0039898413,0.0005808579,0.00032203333,0.000004325896,0.000024139403,0.0009195743],"genre_scores_gemma":[0.99564433,0.002994891,0.00006485392,0.0003258242,0.0005322051,0.000010159424,0.000008280747,0.000025409627,0.00039406837],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99392253,0.0005367327,0.00066588115,0.00034511735,0.0038585095,0.00067121186],"domain_scores_gemma":[0.996663,0.0020686637,0.00023813562,0.00017271069,0.00028024337,0.00057727087],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0034869686,0.00018706544,0.00041665533,0.00082256796,0.00020383047,0.00003168565,0.00043795272,0.00016323084,0.00033039312],"category_scores_gemma":[0.014102666,0.00011751877,0.00005320604,0.0013348568,0.0014245096,0.00058925577,0.0001028068,0.0013372115,0.000014049121],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095879583,0.00017821937,0.95857847,0.00019352286,0.000015186262,0.000116880474,0.001979325,0.00001537054,0.0010045727,0.00012877188,0.011507763,0.025323102],"study_design_scores_gemma":[0.0054310006,0.0010752191,0.9362742,0.0007872302,0.000008191066,0.00001551704,0.001920327,0.00004165421,0.00024963423,0.0011165484,0.052871235,0.00020926111],"about_ca_topic_score_codex":0.000045698227,"about_ca_topic_score_gemma":0.00094229536,"teacher_disagreement_score":0.041363474,"about_ca_system_score_codex":0.000091518334,"about_ca_system_score_gemma":0.0003064091,"threshold_uncertainty_score":0.99420196},"labels":[],"label_agreement":null},{"id":"W4382355800","doi":"10.3390/nu15092215","title":"Membrane Lipids in Ultra-High-Risk Patients: Potential Predictive Biomarkers of Conversion to Psychosis","year":2023,"lang":"en","type":"article","venue":"Nutrients","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fondation Bettencourt Schueller; European College of Neuropsychopharmacology; Agence Nationale de la Recherche","keywords":"Psychosis; Medicine; Internal medicine; Psychiatry","score_opus":0.00971960044360142,"score_gpt":0.23672419297712655,"score_spread":0.22700459253352512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382355800","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99724776,0.0000032748317,0.00007013603,0.00015410564,0.0010912176,0.0005530293,0.00023660291,0.00009515804,0.00054870284],"genre_scores_gemma":[0.9993896,0.00013800742,0.000030327077,0.00026124995,0.000025315268,0.000028885512,0.00002371082,0.000019313873,0.00008358513],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99825364,0.00017055747,0.00028361162,0.00047266553,0.00048027156,0.00033922723],"domain_scores_gemma":[0.999324,0.00014948595,0.00011234484,0.00024063262,0.00004837361,0.00012516578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015570482,0.00014566112,0.00018520067,0.0004604025,0.00008701592,0.000014637312,0.0003000737,0.00008791924,0.00006981105],"category_scores_gemma":[0.00065014965,0.00014180824,0.00007577859,0.0017512401,0.00009844998,0.00015310023,0.000064265354,0.00013107392,0.00022030436],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004481527,0.0031209956,0.4872714,0.00024994914,0.000072156974,0.00002795365,0.004287332,0.00074584316,0.45507324,0.00014818157,0.03333905,0.011182353],"study_design_scores_gemma":[0.0064853844,0.0006302254,0.41684553,0.00009497364,0.000013318255,3.677053e-7,0.00047411985,0.00033676333,0.5730636,0.00020691176,0.0016039376,0.00024484418],"about_ca_topic_score_codex":0.00014083552,"about_ca_topic_score_gemma":0.0000048614593,"teacher_disagreement_score":0.11799037,"about_ca_system_score_codex":0.000043748158,"about_ca_system_score_gemma":0.0000151588,"threshold_uncertainty_score":0.57827723},"labels":[],"label_agreement":null},{"id":"W4382358098","doi":"10.1016/j.bbih.2023.100664","title":"C-Reactive protein and cognition: Mediation analyses with brain morphology in the UK Biobank","year":2023,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; Douglas College","funders":"Canada First Research Excellence Fund; McGill University","keywords":"Biobank; Cognition; Mediation; Context (archaeology); Brain morphometry; Effects of sleep deprivation on cognitive performance; Psychology; Cohort; C-reactive protein; Cognitive decline; Medicine; Internal medicine; Clinical psychology; Inflammation; Neuroscience; Dementia; Bioinformatics; Magnetic resonance imaging; Biology","score_opus":0.10444114586915135,"score_gpt":0.38365478131329295,"score_spread":0.2792136354441416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382358098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97752714,0.0000619357,0.000026449312,0.020540567,0.000051572897,0.0013979507,0.00006497449,0.00012454804,0.00020487221],"genre_scores_gemma":[0.9923094,0.00002521134,0.00005863298,0.0069814944,0.000026207017,0.0003642524,0.00010809652,0.000021900827,0.00010481413],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.997022,0.0014458887,0.00030820095,0.00039547906,0.00034792995,0.0004805015],"domain_scores_gemma":[0.99823534,0.0010625268,0.0001889401,0.0003826605,0.000034227207,0.00009627658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010565263,0.00020160082,0.00025494798,0.0003536451,0.0004647257,0.00006882021,0.00031076366,0.00009470817,0.000056580568],"category_scores_gemma":[0.0008185817,0.0001491354,0.00004023061,0.0015906286,0.00038906906,0.00018185844,0.00006033395,0.0005019213,0.000037569796],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039034282,0.0011818846,0.017342351,0.00013065331,0.000015057978,0.0003278303,0.017900633,0.000011788056,0.9327359,0.0019177543,0.00503231,0.0230135],"study_design_scores_gemma":[0.0021809826,0.0008990285,0.9633031,0.000074784395,0.000013831822,0.00013268832,0.009380713,0.00003614144,0.022547279,0.00057026185,0.00053207955,0.0003291227],"about_ca_topic_score_codex":0.0015254036,"about_ca_topic_score_gemma":0.0014009816,"teacher_disagreement_score":0.94596076,"about_ca_system_score_codex":0.000061978404,"about_ca_system_score_gemma":0.00021505433,"threshold_uncertainty_score":0.6081565},"labels":[],"label_agreement":null},{"id":"W4383068457","doi":"10.3390/biomedicines11071884","title":"Life Experience Matters: Enrichment and Stress Can Influence the Likelihood of Developing Alzheimer’s Disease via Gut Microbiome","year":2023,"lang":"en","type":"review","venue":"Biomedicines","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Microbiome; Disease; Gut microbiome; Biology; Psychology; Gerontology; Neuroscience; Medicine; Bioinformatics; Internal medicine","score_opus":0.07011352007297414,"score_gpt":0.3390221772660045,"score_spread":0.26890865719303036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383068457","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014075468,0.9941685,0.000023465256,0.0024499015,0.0005277695,0.0010053352,0.00031100985,0.0000983202,0.000008120785],"genre_scores_gemma":[0.001814027,0.9945377,0.000035250072,0.003131242,0.00014146973,0.00020952222,0.000036695954,0.00005467777,0.000039382074],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99754596,0.00016561808,0.0007019431,0.00069648,0.0003996793,0.0004903428],"domain_scores_gemma":[0.9981379,0.0005143455,0.00044411243,0.00053158234,0.000042374224,0.00032971945],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015630297,0.00045957568,0.00085909665,0.00035279055,0.00018415082,0.000055948323,0.00083592365,0.0001080067,0.000014640007],"category_scores_gemma":[0.00051851,0.00027562972,0.00014095832,0.0012470208,0.00096776854,0.0000851459,0.00041386005,0.00016027445,0.000029360946],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003856099,0.00023171974,0.00022061667,0.044509713,0.0003409882,0.00021411656,0.005469753,0.0000010485614,0.010100602,0.00027309536,0.009291773,0.929308],"study_design_scores_gemma":[0.00052145886,0.00008985141,0.0013605477,0.026096912,0.0006047707,0.000046865243,0.0008863952,0.000006406463,0.0007991628,0.00015697449,0.96841556,0.0010150691],"about_ca_topic_score_codex":0.00011401969,"about_ca_topic_score_gemma":0.000010583347,"teacher_disagreement_score":0.9591238,"about_ca_system_score_codex":0.000033833203,"about_ca_system_score_gemma":0.00047930778,"threshold_uncertainty_score":0.9999696},"labels":[],"label_agreement":null},{"id":"W4383621150","doi":"10.1016/j.jneb.2023.05.019","title":"Anti-Inflammatory Dietary Interventions to Address Mental Health Outcomes: A Scoping Review","year":2023,"lang":"en","type":"review","venue":"Journal of Nutrition Education and Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Psychological intervention; CINAHL; Medicine; PsycINFO; Mental health; Randomized controlled trial; Mood; MEDLINE; Meta-analysis; Systematic review; Mediterranean diet; Psychiatry; Internal medicine","score_opus":0.18164134335571216,"score_gpt":0.47951509610575704,"score_spread":0.2978737527500449,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383621150","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029845987,0.9928087,0.000003647105,0.0020888783,0.0018981055,0.002770399,0.000089840214,0.00003140926,0.000010540372],"genre_scores_gemma":[0.000013804365,0.99730253,0.00016473235,0.0015331627,0.00019738685,0.00049229123,0.000044455217,0.000035258196,0.00021639018],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.99745595,0.00032503862,0.001427051,0.00026964056,0.00032321372,0.00019907462],"domain_scores_gemma":[0.99815625,0.00012253261,0.001177311,0.00017667869,0.000087657754,0.00027954121],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041063447,0.0002488043,0.0012271582,0.0006165606,0.00017749974,0.00008058419,0.00025619208,0.00008229227,0.000104577775],"category_scores_gemma":[0.0002717519,0.00020459307,0.00071527716,0.0004871637,0.000044315937,0.00022953369,0.000057197667,0.00032506787,0.00005817389],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000017349279,0.004113034,0.000012506804,0.29784286,0.000014465384,0.000009977144,0.00011044207,1.3620851e-8,0.00001636821,0.000016443284,0.024081787,0.6737804],"study_design_scores_gemma":[0.00027106874,0.00015576222,0.00040412942,0.77585286,0.0002885657,0.00034350494,0.00022764876,1.9652497e-8,0.000005147193,0.0000066859543,0.22222692,0.00021766526],"about_ca_topic_score_codex":0.0000022963031,"about_ca_topic_score_gemma":0.0000070889246,"teacher_disagreement_score":0.6735627,"about_ca_system_score_codex":0.00014457568,"about_ca_system_score_gemma":0.0007133599,"threshold_uncertainty_score":0.83430636},"labels":[],"label_agreement":null},{"id":"W4383710261","doi":"10.3967/bes2023.059","title":"Obesity is positively Associated with Depression in Older Adults: Role of Systemic Inflammation.","year":2023,"lang":"en","type":"article","venue":"PubMed","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"","keywords":"Medicine; Depression (economics); Obesity; Abdominal obesity; Internal medicine; Odds ratio; Confidence interval; Logistic regression; Incidence (geometry); Systemic inflammation; Inflammation; Metabolic syndrome","score_opus":0.010003712425391473,"score_gpt":0.19980317364458416,"score_spread":0.1897994612191927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383710261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99811834,0.0000451769,0.000005810788,0.00009182345,0.00003225669,0.00066258636,0.000021257396,0.000107588414,0.0009151367],"genre_scores_gemma":[0.9993504,0.000014899227,0.0000020427074,0.00007793007,0.000009036573,0.00033512808,0.000005482722,0.000010927779,0.00019414269],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998996,0.000099733814,0.00017199504,0.00023568302,0.00024158225,0.00025499964],"domain_scores_gemma":[0.99952185,0.00015724641,0.00011712127,0.00011906286,0.000040058047,0.000044672703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016146345,0.00008276542,0.00012871508,0.00014573471,0.00004105225,0.000015300411,0.00014012758,0.000058657475,0.0000071182785],"category_scores_gemma":[0.00054916134,0.000068460504,0.000023429855,0.0009190937,0.00004025039,0.00018757246,0.00004418948,0.00007722911,0.000015523425],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034183502,0.00035399865,0.8559447,0.00018348657,0.000021253985,0.000035651472,0.008056034,0.00017050195,0.076075725,0.00022873197,0.00046031695,0.05812775],"study_design_scores_gemma":[0.00083770085,0.0000064967553,0.8447316,0.00015213409,0.0000021894334,0.0000016844923,0.00039488307,0.00023040084,0.15350594,0.000059333503,0.000004433829,0.000073194286],"about_ca_topic_score_codex":0.00003603181,"about_ca_topic_score_gemma":0.000035710007,"teacher_disagreement_score":0.07743021,"about_ca_system_score_codex":0.000040938678,"about_ca_system_score_gemma":0.000018492474,"threshold_uncertainty_score":0.27917382},"labels":[],"label_agreement":null},{"id":"W4384025597","doi":"10.1016/j.cpnec.2023.100192","title":"Cortisol and cytokines in schizophrenia: A scoping review","year":2023,"lang":"en","type":"review","venue":"Comprehensive Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Schizophrenia (object-oriented programming); PsycINFO; Clinical psychology; Medicine; Etiology; Disease; Psychology; MEDLINE; Bioinformatics; Psychiatry; Internal medicine; Biology","score_opus":0.1656861108869996,"score_gpt":0.4084612164483209,"score_spread":0.24277510556132129,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384025597","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009234778,0.9941214,0.0000040102873,0.00035318086,0.0013078529,0.0034147697,0.000038860704,0.00036433394,0.00030328316],"genre_scores_gemma":[0.0000052830205,0.9962974,0.000043121752,0.0026122942,0.00011696861,0.00062706415,0.000015576508,0.00015761328,0.00012464872],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9946391,0.001035819,0.0012957667,0.0018034992,0.00024970772,0.00097610144],"domain_scores_gemma":[0.9970893,0.0013327212,0.00052303734,0.000851644,0.000046739216,0.00015654063],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000034554683,0.00083588413,0.0032100612,0.00084902724,0.00012641671,0.000052414416,0.0007722086,0.00016469073,0.00005796664],"category_scores_gemma":[0.0008174183,0.00076852535,0.00037701946,0.0015348645,0.00048564805,0.000104713945,0.00057040056,0.0010627116,0.00080701313],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003190462,0.00008642339,0.000002215384,0.2211996,0.000030519088,0.0020215013,0.0000137654015,2.5303416e-7,0.000104942075,0.0007410789,0.002514922,0.77325284],"study_design_scores_gemma":[0.0013820803,0.00025190413,0.000048502377,0.4615529,0.00016758776,0.003637579,0.000009378902,0.0000026681716,0.000012177843,0.00048688365,0.531395,0.001053352],"about_ca_topic_score_codex":0.000010849187,"about_ca_topic_score_gemma":0.00003607476,"teacher_disagreement_score":0.7721995,"about_ca_system_score_codex":0.000033482713,"about_ca_system_score_gemma":0.00016576369,"threshold_uncertainty_score":0.999971},"labels":[],"label_agreement":null},{"id":"W4384080709","doi":"10.1007/978-3-030-42825-9_83-1","title":"Neurobiological Foundations of Mood Disorders","year":2023,"lang":"en","type":"book-chapter","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Mood disorders; Bipolar disorder; Neuroscience; Mood; Epigenetics; Psychology; Major depressive disorder; Diathesis; Biology; Bioinformatics; Psychiatry; Cognition; Genetics; Anxiety; Gene; Immunology","score_opus":0.05987291350806597,"score_gpt":0.2742408441213038,"score_spread":0.2143679306132378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384080709","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019418173,0.000005516293,0.00009182106,0.0005807353,0.00035000808,0.00024538365,0.00007097127,0.00027529,0.9981861],"genre_scores_gemma":[0.10618405,0.00039702636,0.00003851792,0.00025916248,0.000038651157,0.000008346771,0.000025117473,0.000053603966,0.89299554],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9988675,0.000020499616,0.00027249244,0.00046008616,0.00019028198,0.00018913957],"domain_scores_gemma":[0.999079,0.00041771322,0.00012590199,0.0003088557,0.00001682488,0.000051708044],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000041031628,0.00021750225,0.00024716684,0.0001435696,0.000071958915,0.00001861175,0.000340084,0.00020331657,0.0021527447],"category_scores_gemma":[0.00026743993,0.00017783088,0.00020326868,0.000073647425,0.0003458614,0.000043152406,0.00014321646,0.00023002533,0.0011123489],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000084232315,0.000031953197,0.0000073760116,0.000019728974,0.000007115894,0.0000014817751,0.000016338521,0.000009824303,0.0047734915,0.99090594,0.0023599097,0.0018584302],"study_design_scores_gemma":[0.0007301616,0.00041725207,0.0009687823,0.000068791196,0.000030532734,0.000008040893,0.00003141863,0.000093311566,0.004668264,0.7960878,0.19602995,0.0008657041],"about_ca_topic_score_codex":0.0000049518762,"about_ca_topic_score_gemma":0.0001209091,"teacher_disagreement_score":0.19481812,"about_ca_system_score_codex":0.000008388248,"about_ca_system_score_gemma":0.00003641435,"threshold_uncertainty_score":0.9996654},"labels":[],"label_agreement":null},{"id":"W4384299365","doi":"10.3390/nu15143132","title":"The Role of the Kynurenine Pathway in the Pathophysiology of Frailty, Sarcopenia, and Osteoporosis","year":2023,"lang":"en","type":"review","venue":"Nutrients","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Sarcopenia; Kynurenine; Medicine; Osteoporosis; Anabolism; Kynurenine pathway; Internal medicine; Endocrinology; Catabolism; Niacin; Inflammation; Tryptophan; Biology; Metabolism; Biochemistry; Amino acid","score_opus":0.047485296839019114,"score_gpt":0.3040648102500245,"score_spread":0.2565795134110054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384299365","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014492522,0.9828927,1.3481635e-7,0.00011081754,0.00029878836,0.0013146702,0.00019782064,0.000014546031,0.00067802874],"genre_scores_gemma":[0.014352729,0.9851296,0.0000024834173,0.000118304546,0.000030931118,0.00010946122,0.0000055256123,0.000028777722,0.00022218068],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977521,0.0007563292,0.0005204062,0.00035480762,0.00035227087,0.00026410745],"domain_scores_gemma":[0.99745446,0.0013702641,0.0004609962,0.0006681283,0.000021501879,0.000024649004],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034260843,0.00022917966,0.00066155347,0.00007551092,0.00014712539,0.000022612501,0.0013052195,0.00016184372,0.000007745526],"category_scores_gemma":[0.00068692514,0.000096747,0.00024928915,0.0009314138,0.0004776789,0.000031897005,0.00039332555,0.00035708986,0.00001711054],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002106336,0.00015983918,0.00004924627,0.0014872511,0.000014192116,0.0000031537047,0.00086325116,2.6462868e-7,0.0015420855,0.0018912657,0.0004311344,0.99353725],"study_design_scores_gemma":[0.0004271122,0.00010567936,0.0004874429,0.0018651813,0.000036154503,0.0000049752603,0.00034777942,0.0000025500603,0.0020402558,0.007792166,0.98672926,0.00016143521],"about_ca_topic_score_codex":0.00003179863,"about_ca_topic_score_gemma":0.000032750013,"teacher_disagreement_score":0.99337584,"about_ca_system_score_codex":0.000013102961,"about_ca_system_score_gemma":0.00009338548,"threshold_uncertainty_score":0.3945228},"labels":[],"label_agreement":null},{"id":"W4384383488","doi":"10.4088/jcp.22m14731","title":"Association of Attenuated Niacin Response With Inflammatory Imbalance and Prediction of Conversion to Psychosis From Clinical High-risk Stage","year":2023,"lang":"en","type":"article","venue":"The Journal of Clinical Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Psychosis; Association (psychology); Niacin; Stage (stratigraphy); Psychiatry; Psychology; Medicine; Internal medicine; Psychotherapist; Biology","score_opus":0.03477940414934845,"score_gpt":0.33807315908990204,"score_spread":0.3032937549405536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384383488","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921902,0.000043067626,0.0001252904,0.0055071525,0.0017624594,0.00017804482,0.00015211292,0.000023526949,0.000018180033],"genre_scores_gemma":[0.9975475,0.0011232932,0.00031803394,0.0005916645,0.00025606126,8.3708755e-7,0.0000012599313,0.000014978258,0.00014635595],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9951946,0.002171093,0.0016715766,0.00021222791,0.00058927457,0.00016119142],"domain_scores_gemma":[0.99096805,0.0061116843,0.002328453,0.00029082928,0.00015571881,0.00014525978],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006817394,0.00011725898,0.0004928222,0.00012414697,0.00007228215,0.000010343051,0.0003129029,0.00017814402,0.00002682933],"category_scores_gemma":[0.0051981965,0.00007582118,0.0001668791,0.00047152006,0.00021570432,0.00013123335,0.0000567832,0.00060159917,0.000016611],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021913728,0.00023144363,0.95471,0.000023222798,0.00009733191,0.0000020298198,0.00021317307,0.000118006974,0.0072801476,0.000016168053,0.01451829,0.0008764471],"study_design_scores_gemma":[0.004081519,0.0018887144,0.9902828,0.00015547444,0.000097142285,0.0000017055213,0.0003193162,0.00020578806,0.001568702,0.0005088304,0.00081744685,0.00007258173],"about_ca_topic_score_codex":0.000019143477,"about_ca_topic_score_gemma":0.000022142998,"teacher_disagreement_score":0.035572767,"about_ca_system_score_codex":0.000015969297,"about_ca_system_score_gemma":0.00014526625,"threshold_uncertainty_score":0.6223102},"labels":[],"label_agreement":null},{"id":"W4384498439","doi":"10.1139/cjpp-2023-0079","title":"NLG-919 combined with cisplatin to enhance inhibitory effect on cell migration and invasion via IDO1–Kyn–AhR pathway in human nasopharyngeal carcinoma cell","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Cisplatin; Nasopharyngeal carcinoma; Cancer research; Medicine; Apoptosis; Cell culture; Kynurenine; In vitro; Chemotherapy; Pharmacology; Chemistry; Internal medicine; Biology; Amino acid; Tryptophan; Biochemistry; Radiation therapy","score_opus":0.011406648128831173,"score_gpt":0.2510772135001058,"score_spread":0.23967056537127462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384498439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984631,0.00011122767,0.000002030359,0.0005179637,0.0004194646,0.0002853541,0.000010960441,0.000009251585,0.00018065958],"genre_scores_gemma":[0.99769276,0.00002366851,0.000006632992,0.0020281002,0.00011569031,0.000013010757,0.000005219845,0.00001578042,0.0000991402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998537,0.00043732877,0.00024905754,0.00031935825,0.00007884791,0.00037839473],"domain_scores_gemma":[0.9989797,0.0003832739,0.0001463577,0.000078393015,0.000028446137,0.0003838586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022606734,0.00018335495,0.00030600326,0.0004782413,0.0002090512,0.00001324695,0.00015350756,0.00011941434,0.00010296589],"category_scores_gemma":[0.000028170976,0.00015521726,0.000033615073,0.00032545716,0.00021142654,0.00010359973,0.00002514586,0.00041151777,0.000016665232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051824993,0.00003684113,0.0029534486,0.00007438828,0.0000037239101,0.00030771765,0.0006604064,0.00015924005,0.9930942,0.000016000835,0.0016550598,0.00052072416],"study_design_scores_gemma":[0.0019607577,0.004168213,0.037349902,0.000024188817,0.000008236338,0.00002589152,0.000038584898,0.000076067954,0.95564646,0.00023056635,0.0003193792,0.00015175331],"about_ca_topic_score_codex":0.00030573225,"about_ca_topic_score_gemma":0.0039962647,"teacher_disagreement_score":0.037447743,"about_ca_system_score_codex":0.00004952889,"about_ca_system_score_gemma":0.00020098643,"threshold_uncertainty_score":0.63295764},"labels":[],"label_agreement":null},{"id":"W4385071257","doi":"10.1007/s40496-023-00339-y","title":"Periodontal Health and Psychiatric Disorders","year":2023,"lang":"en","type":"article","venue":"Current Oral Health Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"University of Queensland","keywords":"Medicine; Mental illness; Psychiatry; Psychosocial; Exacerbation; Disease; Mental health","score_opus":0.07555403306608488,"score_gpt":0.38105794383427194,"score_spread":0.30550391076818706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385071257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9657884,0.01038909,0.00008761515,0.015880806,0.005453444,0.0010727034,0.00001930386,0.000775011,0.0005336085],"genre_scores_gemma":[0.9892727,0.0077681364,0.00006033451,0.0024864664,0.00010485616,0.000036689038,0.000030280635,0.00003236929,0.00020815154],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974905,0.00015761341,0.00056202576,0.00069156184,0.00036643998,0.00073182763],"domain_scores_gemma":[0.9987441,0.00005502691,0.00032555743,0.0003056955,0.000010084558,0.0005595584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043877438,0.00019501915,0.00029129506,0.0002345341,0.00054964115,0.000053830543,0.00009760629,0.000037838094,0.000026854206],"category_scores_gemma":[0.00019270067,0.0001794559,0.00007664919,0.0009390843,0.00012093939,0.0001371407,0.00009687442,0.00024341264,0.000060463404],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003238537,0.00030102622,0.0527491,0.0008731834,0.0000026179462,0.000046551082,0.0016602844,0.0000060985926,0.000080576814,0.0012292962,0.08878641,0.8542325],"study_design_scores_gemma":[0.0011711129,0.0009893294,0.1815575,0.00016595029,0.0000034290567,0.00040499042,0.0008719029,0.00067534874,0.00006613811,0.0083714975,0.80499023,0.000732577],"about_ca_topic_score_codex":0.00011647541,"about_ca_topic_score_gemma":0.00017384908,"teacher_disagreement_score":0.8534999,"about_ca_system_score_codex":0.000069876456,"about_ca_system_score_gemma":0.00052064436,"threshold_uncertainty_score":0.73179996},"labels":[],"label_agreement":null},{"id":"W4385430793","doi":"10.2147/ndt.s418381","title":"Serum Levels of Tumor Necrosis Factor-α and Vascular Endothelial Growth Factor in the Subtypes of Clinical High Risk Individuals: A Prospective Cohort Study","year":2023,"lang":"en","type":"article","venue":"Neuropsychiatric Disease and Treatment","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Shanghai Clinical Research Center; National Natural Science Foundation of China","keywords":"Medicine; Internal medicine; Vascular endothelial growth factor; Pathological; Pathogenesis; Tumor necrosis factor alpha; Gastroenterology; Prospective cohort study; Cohort; Schizophrenia (object-oriented programming); Tumor necrosis factor α; Risk factor; Oncology; VEGF receptors; Psychiatry","score_opus":0.033668177217841586,"score_gpt":0.2987714640917201,"score_spread":0.2651032868738785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385430793","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99600965,0.00010058877,6.107275e-7,0.00009191811,0.00014976146,0.0017312048,0.0018417753,0.000038061295,0.000036436937],"genre_scores_gemma":[0.9987934,0.00094694813,0.0000072918333,0.000073591895,0.000039475937,0.0000985126,0.0000021274539,0.000019537729,0.00001910352],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976338,0.00065036735,0.00045724303,0.0006176068,0.00040830593,0.000232669],"domain_scores_gemma":[0.9985061,0.0007917719,0.00022632022,0.00032038265,0.000024126211,0.00013128246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019320405,0.00023243054,0.0004208718,0.0001850325,0.00011296132,0.000036846526,0.0001780759,0.000030604555,0.000020646912],"category_scores_gemma":[0.0004500593,0.00014515645,0.00015134507,0.0006782392,0.00016407996,0.00008463347,0.00007219359,0.000116481926,0.000004868153],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014145598,0.002186881,0.99363285,0.000025185991,0.0000909156,0.000036115376,0.0010392454,0.0000018686334,0.00007056596,0.00017821195,0.0000074625545,0.0025892493],"study_design_scores_gemma":[0.003790789,0.0012530475,0.99328315,0.0000069134494,0.00019905905,8.851959e-7,0.00030070424,0.000016960747,0.00028949283,0.00072833034,0.000009624027,0.00012101427],"about_ca_topic_score_codex":0.00029401295,"about_ca_topic_score_gemma":0.000056521905,"teacher_disagreement_score":0.003649333,"about_ca_system_score_codex":0.000010314118,"about_ca_system_score_gemma":0.00008288661,"threshold_uncertainty_score":0.5919308},"labels":[],"label_agreement":null},{"id":"W4385476665","doi":"10.1002/hbm.26439","title":"The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease","year":2023,"lang":"en","type":"article","venue":"Human Brain Mapping","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Disease; Inflammatory bowel disease; Neuroscience; Medicine; Depressive symptoms; Psychology; Depression (economics); Internal medicine; Cognition","score_opus":0.02100527042995568,"score_gpt":0.24675104882582652,"score_spread":0.22574577839587084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385476665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967304,0.00003217991,0.000020863434,0.0025320475,0.000020137273,0.00052462536,0.000012093677,0.000041537154,0.00008611774],"genre_scores_gemma":[0.9993856,0.000001951756,0.0000024442902,0.0004596999,0.000023716662,0.00006863164,0.000011977637,0.00001753829,0.000028457966],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99851763,0.00038061276,0.00030877933,0.00027067724,0.00025766063,0.00026464506],"domain_scores_gemma":[0.9954501,0.004120322,0.00012834196,0.00023031289,0.000013864065,0.00005709073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034507236,0.00012006234,0.00010006736,0.00019959711,0.0005302853,0.00006998908,0.00024494712,0.000030236044,0.0000017145417],"category_scores_gemma":[0.0016886863,0.000082837665,0.00002702045,0.0005079504,0.00025723,0.00018715949,0.00007064899,0.00023801178,0.0000023432065],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011357445,0.0000123127675,0.9895531,0.000021370546,0.000002574899,0.00000299635,0.0033744986,0.00037549165,0.0031445033,0.003001743,0.00002840991,0.0004716547],"study_design_scores_gemma":[0.0007861019,0.000017507478,0.993007,0.00009251478,0.000002274494,9.6743925e-8,0.0003693579,0.00059324014,0.00007594325,0.004889752,0.000068545065,0.000097632554],"about_ca_topic_score_codex":0.0000096288395,"about_ca_topic_score_gemma":0.00007270263,"teacher_disagreement_score":0.003739709,"about_ca_system_score_codex":0.00001705192,"about_ca_system_score_gemma":0.000031058196,"threshold_uncertainty_score":0.40785792},"labels":[],"label_agreement":null},{"id":"W4385496906","doi":"10.1186/s12888-023-05050-x","title":"Decrease in cognitive performance and increase of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios with higher doses of antipsychotics in women with schizophrenia: a cross-sectional study","year":2023,"lang":"en","type":"article","venue":"BMC Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Schizophrenia (object-oriented programming); Cognitive flexibility; Lymphocyte; Antipsychotic; Internal medicine; Medicine; Schizoaffective disorder; Psychiatry; Clinical psychology; Working memory; Neuropsychology; Cognition; Psychology; Psychosis","score_opus":0.02024352579887523,"score_gpt":0.2686921462440999,"score_spread":0.2484486204452247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385496906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985167,0.000056852077,0.00000506408,0.000052393905,0.00016132557,0.0010509833,0.000049135007,0.000029029077,0.000078541205],"genre_scores_gemma":[0.9991555,0.000043543983,0.00020078185,0.00039698512,0.000029142102,0.00009969666,0.0000010858269,0.000027155353,0.000046095152],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998283,0.00013474947,0.00036128587,0.0005334072,0.000360211,0.00032734763],"domain_scores_gemma":[0.9992264,0.00016482653,0.00014061734,0.0002523021,0.000046177756,0.00016965518],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002294266,0.0002238489,0.00028294255,0.00037180516,0.000116014366,0.000047352813,0.00020699724,0.000057785983,0.000010886292],"category_scores_gemma":[0.00011606495,0.00015559561,0.000020199706,0.0017404167,0.0002881139,0.00016909794,0.000114301336,0.00014482877,0.0000036864526],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022039983,0.00044333574,0.9738301,0.0001042005,0.000012507292,0.000005550979,0.0009288668,0.00061312615,0.0017225085,0.00006581475,0.000009771558,0.0002242478],"study_design_scores_gemma":[0.01222552,0.0009687201,0.98376054,0.00021858158,0.0000062283348,0.000025228434,0.00075044675,0.00016880124,0.0015964169,0.00007642316,0.0000056154486,0.00019750671],"about_ca_topic_score_codex":0.00013013603,"about_ca_topic_score_gemma":0.00091959577,"teacher_disagreement_score":0.009930425,"about_ca_system_score_codex":0.000044876182,"about_ca_system_score_gemma":0.00044370384,"threshold_uncertainty_score":0.6345005},"labels":[],"label_agreement":null},{"id":"W4385542251","doi":"10.1101/2023.08.03.551808","title":"The ketamine metabolite ( <i>2R,6R</i> )-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer’s disease","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Carleton University; Queen's University; Centre for Research on Brain Language and Music; McGill University","funders":"National Institutes of Health; National Institute of Neurological Disorders and Stroke; Instituto Nacional de Ciência e Tecnologia de Neurociência Translacional; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Universidade Federal do Rio de Janeiro; Alzheimer's Association; International Brain Research Organization; Instituto Serrapilheira; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Company of Biologists; Alzheimer's Society; American Society for Biochemistry and Molecular Biology; International Society for Neurochemistry","keywords":"Long-term potentiation; Hippocampal formation; Synaptic plasticity; mTORC1; Neuroscience; Memory consolidation; P70-S6 Kinase 1; PI3K/AKT/mTOR pathway; Hippocampus; Biology; Ribosomal protein s6; Signal transduction; Cell biology; Biochemistry","score_opus":0.039749118762229745,"score_gpt":0.23952150935512911,"score_spread":0.19977239059289936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385542251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887523,0.0069699325,0.00070068915,0.0005543803,0.00054298836,0.0013031089,0.00078062876,0.00038596158,0.000009985219],"genre_scores_gemma":[0.995504,0.0034681102,0.00034653704,0.00016806061,0.00012039483,0.00022578762,6.451883e-7,0.00015335777,0.000013102067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99566877,0.0005277827,0.000996649,0.0013592595,0.0006996807,0.00074786035],"domain_scores_gemma":[0.9969307,0.0008808694,0.00047937807,0.0011228085,0.00020110363,0.0003850972],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008254845,0.0006720379,0.0008002957,0.00042187265,0.0002591779,0.00020148637,0.0008343758,0.00030868073,0.0000063449943],"category_scores_gemma":[0.001377216,0.00058639405,0.0001889869,0.0010052465,0.00071564666,0.00032057505,0.00046966574,0.0007848183,0.000013107458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037084756,0.0003465856,0.0013419471,0.0006202592,0.00020017433,0.0000953996,0.000096940836,0.007609472,0.98723257,0.0019693312,0.00008115551,0.000035291396],"study_design_scores_gemma":[0.0031153825,0.00010668665,0.11808242,0.00070093136,0.0005786763,6.117968e-8,0.000033161148,0.10219196,0.77223945,0.0003827353,0.0005328332,0.0020357068],"about_ca_topic_score_codex":0.00008478746,"about_ca_topic_score_gemma":0.000023610357,"teacher_disagreement_score":0.21499315,"about_ca_system_score_codex":0.000059253012,"about_ca_system_score_gemma":0.00043558574,"threshold_uncertainty_score":0.99965876},"labels":[],"label_agreement":null},{"id":"W4385565479","doi":"10.1186/s12916-023-02920-9","title":"Neurodevelopmental risk and adaptation as a model for comorbidity among internalizing and externalizing disorders: genomics and cell-specific expression enriched morphometric study","year":2023,"lang":"en","type":"article","venue":"BMC Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; Western University","funders":"National Natural Science Foundation of China","keywords":"Medicine; Comorbidity; Genomics; Adaptation (eye); Bioinformatics; Neuroscience; Psychiatry; Genetics; Genome; Gene; Biology","score_opus":0.08574579043597581,"score_gpt":0.29417331019800314,"score_spread":0.20842751976202734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385565479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96924007,0.000780152,0.0288981,0.000039580176,0.000147355,0.0007598914,0.000007713563,0.000080855876,0.000046259767],"genre_scores_gemma":[0.99505454,0.0033834355,0.0011790444,0.00008763952,0.00004607073,0.000054830376,0.000005243082,0.000029612393,0.00015958553],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99850315,0.0001161394,0.00030739506,0.0005793658,0.0002580832,0.00023588775],"domain_scores_gemma":[0.9988707,0.00066412333,0.00016985108,0.00014827686,0.00001632846,0.00013076745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004551297,0.00019114824,0.00022976783,0.00037962451,0.00026429933,0.00005847835,0.00012500217,0.000042382293,0.000007776599],"category_scores_gemma":[0.0006351812,0.00016111905,0.000020929723,0.00041624444,0.00017237611,0.00018258225,0.00018282619,0.00013427902,0.0000019384468],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058869424,0.00037330686,0.2989487,0.00033666374,0.000014927905,0.0000313426,0.05041859,0.0010181011,0.595993,0.000117917865,0.0013020888,0.050856695],"study_design_scores_gemma":[0.007639018,0.0006002837,0.4123539,0.000121833174,0.000036750927,0.000015701875,0.01784287,0.55426556,0.0042496887,0.002215808,0.00024066021,0.00041791203],"about_ca_topic_score_codex":0.00010265866,"about_ca_topic_score_gemma":0.00006152082,"teacher_disagreement_score":0.5917433,"about_ca_system_score_codex":0.000022811293,"about_ca_system_score_gemma":0.000019267123,"threshold_uncertainty_score":0.65702444},"labels":[],"label_agreement":null},{"id":"W4385594438","doi":"10.12998/wjcc.v11.i22.5215","title":"Changes in neurotransmitter levels, brain structural characteristics, and their correlation with PANSS scores in patients with first-episode schizophrenia","year":2023,"lang":"en","type":"article","venue":"World Journal of Clinical Cases","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Medicine; Corpus callosum; Internal medicine; Positive and Negative Syndrome Scale; Fornix; Psychiatry; Psychosis; Pathology; Hippocampus","score_opus":0.05254077281203447,"score_gpt":0.307020466034213,"score_spread":0.25447969322217856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385594438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965067,0.000023131037,0.000016206908,0.0029731314,0.00022697916,0.00019171194,0.00003513672,0.000016264552,0.0000107715405],"genre_scores_gemma":[0.9985825,0.000053455395,0.00005609907,0.0011335969,0.000104058716,0.000002971824,0.000003478888,0.00002030056,0.000043563683],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998345,0.0002458906,0.00064146606,0.00025956743,0.0002620796,0.00024599308],"domain_scores_gemma":[0.996563,0.0027853576,0.00037936534,0.00011583865,0.00004926583,0.00010717175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034426074,0.00017379149,0.00041674307,0.0003669263,0.000063588144,0.00005530068,0.00015679866,0.000049254264,0.000029535504],"category_scores_gemma":[0.0014867972,0.000106391555,0.000048394228,0.0005920538,0.00023179394,0.00023918103,0.000031975153,0.00049207197,0.0000026217483],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023418756,0.0000789459,0.98265237,0.000025995394,0.000005429379,0.0002493783,0.00018107708,0.000077931836,0.000038309674,0.000029036912,0.00012493451,0.014194743],"study_design_scores_gemma":[0.003968876,0.00082354195,0.99384964,0.00029851653,0.0000053271256,0.000035777895,0.000032213862,0.00029418353,0.00015485438,0.00014466884,0.00024871205,0.00014370946],"about_ca_topic_score_codex":0.000018704211,"about_ca_topic_score_gemma":0.0072217262,"teacher_disagreement_score":0.014051033,"about_ca_system_score_codex":0.000011721489,"about_ca_system_score_gemma":0.000040583396,"threshold_uncertainty_score":0.43385217},"labels":[],"label_agreement":null},{"id":"W4385614663","doi":"10.1016/j.jad.2023.08.039","title":"Mitochondrial health, NLRP3 inflammasome activation, and white matter integrity in adolescent mood disorders: A pilot study","year":2023,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Bipolar disorder; Inflammasome; Mood disorders; White matter; Mood; Major depressive disorder; Fractional anisotropy; Psychology; Internal medicine; Medicine; Psychiatry; Anxiety; Magnetic resonance imaging; Inflammation","score_opus":0.02812777693833132,"score_gpt":0.2982463717554016,"score_spread":0.2701185948170703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385614663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896954,0.000039150902,0.0003798608,0.00768364,0.0005578108,0.0011933354,0.000007061763,0.000049867875,0.0003938174],"genre_scores_gemma":[0.9987826,0.0002632674,0.000036586818,0.0006714311,0.0001117346,0.000034839082,0.00000146558,0.000040124753,0.000057967936],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971022,0.0007331077,0.0006422652,0.00047024895,0.00054520374,0.0005069778],"domain_scores_gemma":[0.9986347,0.00043502825,0.0004740235,0.0002142004,0.00006903009,0.00017300814],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005471559,0.00030512625,0.0004794157,0.00082982116,0.0001877523,0.00010492557,0.0003206917,0.00006394833,0.00004594719],"category_scores_gemma":[0.0009638023,0.00026689368,0.000106795094,0.0014211119,0.00017120883,0.0006463117,0.00012488881,0.0008854775,0.000033899523],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016306788,0.004458271,0.95195407,0.00014545482,0.000055577224,0.000011509571,0.009132021,0.00042727697,0.012802314,0.00010402858,0.0048084306,0.014470364],"study_design_scores_gemma":[0.0061045727,0.00345589,0.9791811,0.00013766627,0.000008348749,0.000009002452,0.006982253,0.00008306363,0.0006202133,0.0029253077,0.00021346695,0.00027907526],"about_ca_topic_score_codex":0.00019014713,"about_ca_topic_score_gemma":0.004492392,"teacher_disagreement_score":0.027227066,"about_ca_system_score_codex":0.00015516901,"about_ca_system_score_gemma":0.00016375592,"threshold_uncertainty_score":0.9999783},"labels":[],"label_agreement":null},{"id":"W4385622232","doi":"10.1523/eneuro.0106-23.2023","title":"Reelin Rescues Behavioral, Electrophysiological, and Molecular Metrics of a Chronic Stress Phenotype in a Similar Manner to Ketamine","year":2023,"lang":"en","type":"article","venue":"eNeuro","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Reelin; Hippocampal formation; Dentate gyrus; NMDA receptor; Neuroscience; Hippocampus; Ketamine; DAB1; Long-term potentiation; Endocrinology; Corticosterone; Synaptic plasticity; Pharmacology; Internal medicine; Medicine; Psychology; Receptor; Hormone","score_opus":0.03293972110182055,"score_gpt":0.29490572443650537,"score_spread":0.26196600333468484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385622232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989226,0.00019931725,0.00001886514,0.00040857645,0.00005467798,0.00021316476,0.00001812069,0.00007640025,0.00008828836],"genre_scores_gemma":[0.9988433,0.0003533562,0.00006747024,0.0005738898,0.000017662684,0.000019796102,0.0000038786156,0.000019792158,0.00010083587],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987523,0.00012094048,0.00018822704,0.0004219794,0.00020637453,0.00031016758],"domain_scores_gemma":[0.9994735,0.00015184646,0.000041243173,0.0002477697,0.000017092972,0.00006850738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007503,0.00013022117,0.00019162467,0.0003231896,0.00003477015,0.000018769228,0.00022768618,0.000053590036,0.000023401162],"category_scores_gemma":[0.0005816169,0.00011485273,0.00004014174,0.0016885712,0.00007734805,0.00004727818,0.00015796533,0.00013802531,0.000024235205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039964558,0.00013808637,0.00015520483,0.000022263062,0.0000010237999,0.0001282927,0.000060020928,0.00047424724,0.9961697,0.00026578916,0.00038728345,0.002158122],"study_design_scores_gemma":[0.0005121984,0.0011903569,0.015475736,0.000024619174,0.0000057422567,0.0000017934445,0.0000378769,0.0009646925,0.9798388,0.00049141137,0.001259391,0.00019741133],"about_ca_topic_score_codex":0.00002479477,"about_ca_topic_score_gemma":0.000023374367,"teacher_disagreement_score":0.016330931,"about_ca_system_score_codex":0.000018186382,"about_ca_system_score_gemma":0.000022404765,"threshold_uncertainty_score":0.46835583},"labels":[],"label_agreement":null},{"id":"W4385648811","doi":"10.1016/j.heliyon.2023.e18909","title":"A review of new insights into existing major depressive disorder biomarkers","year":2023,"lang":"en","type":"review","venue":"Heliyon","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Major depressive disorder; Bioinformatics; Biomarker; Epigenetics; Endocrine system; Endophenotype; Depression (economics); Metabolomics; Bipolar disorder; Medicine; Narrative review; Biomarker discovery; Neuroscience; Biology; Proteomics; Internal medicine; Cognition; Hormone; Intensive care medicine; Genetics; Gene","score_opus":0.09797489128379983,"score_gpt":0.3629189349679734,"score_spread":0.26494404368417357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385648811","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000047848075,0.9947933,0.00004066995,0.000066362205,0.00041170616,0.0013370322,0.000021629849,0.00019039141,0.0031341403],"genre_scores_gemma":[6.460434e-7,0.99749345,0.00009408106,0.000616432,0.0001227632,0.00012386795,0.000036911566,0.00012075662,0.0013910781],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99688274,0.00036360294,0.0010296142,0.0008949663,0.0004246413,0.00040442118],"domain_scores_gemma":[0.9974645,0.00074598123,0.00084343145,0.00072076696,0.000044421024,0.00018093725],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015813697,0.00054756424,0.0017318197,0.00035663752,0.00013801423,0.000037305992,0.0008125879,0.00026319234,0.0001816937],"category_scores_gemma":[0.0029679937,0.0004244009,0.0006796231,0.0018001951,0.00015023739,0.00011673868,0.00033799515,0.00035845413,0.0005589403],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000028105799,0.00002883896,3.2798803e-7,0.38061622,0.000037559457,0.00002400666,0.00007707371,5.4761372e-8,0.000035975627,0.00020085482,0.0030616214,0.61591464],"study_design_scores_gemma":[0.00016425742,0.00002330274,7.1404605e-7,0.32339513,0.00015629406,0.000009830962,0.000010421359,6.034261e-7,0.00008134478,0.0001932915,0.6756678,0.00029695086],"about_ca_topic_score_codex":0.00006162753,"about_ca_topic_score_gemma":0.000047571804,"teacher_disagreement_score":0.6726062,"about_ca_system_score_codex":0.000059335416,"about_ca_system_score_gemma":0.00042763038,"threshold_uncertainty_score":0.99982077},"labels":[],"label_agreement":null},{"id":"W4385663782","doi":"10.14293/p2199-8442.1.sop-.padgts.v1","title":"Exploring lnflammasome/Cytokine/lnsulin cascade as converging landscape for AD, Schizophrenia(SCHIZO);and COVID-19 syndrome: synthesis of evidence and Post-hoc analysis of Ginsana-115 RCT in treatment-resistant-schizophrenia","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Lawson Health Research Institute; McMaster University; London Health Sciences Centre; Western University","funders":"","keywords":"Dementia; Schizophrenia (object-oriented programming); Neurocognitive; Medicine; Metabolic syndrome; Internal medicine; Randomized controlled trial; Psychosis; Post-hoc analysis; Insulin resistance; Psychiatry; Insulin; Cognition; Obesity; Disease","score_opus":0.18143602229811953,"score_gpt":0.33268850278373757,"score_spread":0.15125248048561804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385663782","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930642,0.0019044228,0.00020713435,0.0014216042,0.0002211817,0.0016370981,0.0012635696,0.00023021281,0.000050537084],"genre_scores_gemma":[0.98538935,0.011972826,0.0012340427,0.00012848999,0.00003134409,0.0007497224,0.000053479685,0.00011671709,0.00032404193],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9944006,0.0004363123,0.0014975594,0.0021441276,0.0007365468,0.0007848189],"domain_scores_gemma":[0.9901264,0.0072857337,0.0008844405,0.0010963365,0.00012331072,0.00048379813],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008517515,0.0009242667,0.0023086104,0.003166411,0.00022685908,0.00016277168,0.00079939293,0.00039589495,0.00014960463],"category_scores_gemma":[0.00647787,0.00077772717,0.00067972625,0.0021899112,0.0004900258,0.00047986675,0.00080655084,0.00043344178,0.000008776058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.107117586,0.0031401757,0.0305656,0.030104233,0.013110873,0.0034887677,0.02066882,0.047147375,0.6289217,0.010453546,0.00036405382,0.10491729],"study_design_scores_gemma":[0.034658343,0.0061863745,0.26998982,0.009189806,0.012764196,0.00031657665,0.014621019,0.06933015,0.56703943,0.006759384,0.00088258676,0.008262348],"about_ca_topic_score_codex":0.0024170107,"about_ca_topic_score_gemma":0.0039756014,"teacher_disagreement_score":0.2394242,"about_ca_system_score_codex":0.00023271858,"about_ca_system_score_gemma":0.0007166363,"threshold_uncertainty_score":0.9994674},"labels":[],"label_agreement":null},{"id":"W4385670146","doi":"10.1192/j.eurpsy.2023.658","title":"Decreased plasma concentrations of kynurenine and kynurenic acid in schizophrenia patients","year":2023,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Campbell Family Mental Health Research Institute; Queen's University; University of Toronto; McMaster University; University of Texas Southwestern Medical Center","keywords":"Kynurenic acid; Kynurenine; Kynurenine pathway; Schizophrenia (object-oriented programming); Internal medicine; NMDA receptor; Quinolinic acid; Endocrinology; Positive and Negative Syndrome Scale; Tryptophan; Medicine; Chemistry; Psychosis; Pharmacology; Psychiatry; Receptor; Biochemistry; Amino acid","score_opus":0.014221988469871695,"score_gpt":0.23718511305624052,"score_spread":0.22296312458636883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385670146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992052,0.00008993055,0.0000074347167,0.00033838622,0.0005288279,0.00018224634,0.00004084859,0.00012116275,0.0066391416],"genre_scores_gemma":[0.99918294,0.000040892424,0.00025510142,0.00028871416,0.00005360167,0.000003516732,0.000019966083,0.000029495011,0.00012577916],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99870384,0.00021718715,0.00029916415,0.0003490279,0.00018466069,0.0002461386],"domain_scores_gemma":[0.9994942,0.0000684661,0.000098777244,0.00022467824,0.000015430895,0.000098471166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012026039,0.00013920572,0.0001391107,0.00019235791,0.00007848425,0.000025867956,0.00021625054,0.000029345681,0.000052349416],"category_scores_gemma":[0.00026443298,0.00013497841,0.000046823097,0.000729475,0.0001344483,0.00010583786,0.00007012675,0.00014039714,0.00017367114],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016005904,0.0020273176,0.52298486,0.00027506598,0.000041094972,0.00007794252,0.004878502,0.00011973953,0.34947053,0.05067554,0.03490291,0.03294589],"study_design_scores_gemma":[0.0086577125,0.0002487969,0.9692353,0.00018151461,0.000010571467,0.0000053048475,0.0003290845,0.00050588854,0.01784198,0.0012409069,0.0013607835,0.0003821413],"about_ca_topic_score_codex":0.0000033174238,"about_ca_topic_score_gemma":0.000037949605,"teacher_disagreement_score":0.44625044,"about_ca_system_score_codex":0.000006800291,"about_ca_system_score_gemma":0.000047264395,"threshold_uncertainty_score":0.550426},"labels":[],"label_agreement":null},{"id":"W4385685649","doi":"10.4049/jimmunol.210.supp.234.04","title":"Elevated C-reactive protein and depression score among post-COVID-19 patients - A cross-sectional study","year":2023,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Depression (economics); Anxiety; Medicine; Internal medicine; Coronavirus disease 2019 (COVID-19); C-reactive protein; Cross-sectional study; Microbiome; Biomarker; Cohort study; Cohort; Mini-international neuropsychiatric interview; Immunology; Psychiatry; Disease; Biology; Bioinformatics; Inflammation; Pathology","score_opus":0.03189057862417216,"score_gpt":0.30398349752810844,"score_spread":0.2720929189039363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385685649","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989741,0.000041868392,0.000009870405,0.00018862332,0.00027540635,0.0004305239,0.000006317361,0.000034107663,0.00003920822],"genre_scores_gemma":[0.9995668,0.000015084058,0.0000028540583,0.00023065397,0.000029961357,0.000008149473,0.0000011847318,0.000011546259,0.00013375534],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99856615,0.0005016825,0.00031398694,0.00015247642,0.00025751488,0.00020820399],"domain_scores_gemma":[0.998897,0.0004089358,0.0003500352,0.0001480215,0.00013565838,0.00006035175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050786184,0.00010780815,0.00014735086,0.0002091644,0.00033030464,0.000040053772,0.00032773355,0.00006973664,0.000033940338],"category_scores_gemma":[0.0027866662,0.00006674189,0.00004445379,0.00034649015,0.00034544198,0.00022488544,0.00016407725,0.0003821183,0.000020522933],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001351235,0.00026912955,0.52696383,0.000004952204,0.000036146674,0.000035111345,0.0018094216,0.000039664636,0.46902856,0.000014098838,0.000057546575,0.00039031],"study_design_scores_gemma":[0.002149931,0.00078468997,0.9579566,0.000009867403,0.0000064450637,0.00007043405,0.0008593077,0.0000150585165,0.037454545,0.0005960942,0.000028492874,0.00006849809],"about_ca_topic_score_codex":0.00007551716,"about_ca_topic_score_gemma":0.00001563783,"teacher_disagreement_score":0.43157402,"about_ca_system_score_codex":0.000049436207,"about_ca_system_score_gemma":0.00008854355,"threshold_uncertainty_score":0.3336101},"labels":[],"label_agreement":null},{"id":"W4385799047","doi":"10.1016/j.bbi.2023.08.011","title":"Disrupting T cell memory to promote stress resilience: A role for CD74?","year":2023,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Université du Québec à Montréal; McGill University; University of British Columbia; University of Victoria","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Michael Smith Health Research BC","keywords":"Resilience (materials science); Stress (linguistics); Psychological resilience; Class (philosophy); Psychology; Computer science; Social psychology; Artificial intelligence; Materials science","score_opus":0.029547526958959625,"score_gpt":0.30682625701261806,"score_spread":0.27727873005365844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385799047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969783,0.000030939736,0.000042414053,0.00030384585,0.00013293052,0.0008954427,0.00011992474,0.0002119625,0.0012842594],"genre_scores_gemma":[0.9952931,0.00001168699,0.00019593516,0.00046217008,0.000031900676,0.00023512368,0.000014786331,0.000027993527,0.0037273318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867904,0.000108274995,0.00018719501,0.00038690493,0.00018628026,0.00045230595],"domain_scores_gemma":[0.999013,0.00041473607,0.000052312687,0.00034311923,0.00002678947,0.00015004477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003176549,0.00016323054,0.0001556242,0.00013508994,0.00053002976,0.0001029376,0.00034436796,0.00006985423,0.000019540066],"category_scores_gemma":[0.00091908727,0.00015641062,0.00006743504,0.0003921233,0.00010871568,0.00015579342,0.00023482299,0.00017867808,0.000045169465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023706985,0.00016672135,0.0011198923,0.000045850025,7.1415894e-7,0.000008863455,0.0025999818,0.000011293096,0.9636762,0.00008724239,0.001009773,0.031249747],"study_design_scores_gemma":[0.0009918372,0.00031367654,0.12197438,0.000042502114,0.000013129161,0.000008262117,0.005951802,0.00026440906,0.8646464,0.00026917955,0.005227777,0.00029665386],"about_ca_topic_score_codex":0.00006715745,"about_ca_topic_score_gemma":0.000023269937,"teacher_disagreement_score":0.12085448,"about_ca_system_score_codex":0.000015118149,"about_ca_system_score_gemma":0.000031454336,"threshold_uncertainty_score":0.637824},"labels":[],"label_agreement":null},{"id":"W4385803347","doi":"10.20944/preprints202308.0981.v1","title":"Sarcosine May Induce EGF Production or Inhibit the Decline in EGF Concentrations in Patients with Chronic Schizophrenia (Results of the PULSAR Study)","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Sarcosine; Positive and Negative Syndrome Scale; Placebo; Schizophrenia (object-oriented programming); Internal medicine; Antipsychotic; Psychology; Medicine; Endocrinology; Psychosis; Psychiatry; Chemistry; Glycine; Biochemistry","score_opus":0.11310414589887507,"score_gpt":0.3334323193080028,"score_spread":0.22032817340912775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385803347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905427,0.000021189808,0.0000022014642,0.0038213548,0.00075913314,0.0045432546,0.000086206775,0.00008217271,0.0001418046],"genre_scores_gemma":[0.99864346,0.00005924925,0.000011435904,0.00014853007,0.000095586605,0.00035145166,0.000027141346,0.000051864878,0.00061127794],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9956589,0.0007147559,0.00097128947,0.0014120179,0.00079623755,0.00044682572],"domain_scores_gemma":[0.99711597,0.0002609959,0.00063203054,0.0018076096,0.00012625361,0.000057145255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091129297,0.00039379988,0.00042955027,0.00024336309,0.00016366832,0.000037362282,0.0013053371,0.00018492862,0.000057193865],"category_scores_gemma":[0.0034062613,0.00023426652,0.0000936987,0.001519842,0.00039808534,0.00016139665,0.0021485996,0.0013610843,0.000088671564],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017445154,0.0019823005,0.9739491,0.000103657694,0.000027630467,0.000007685164,0.0024387077,0.0070098448,0.012026483,0.00006354711,0.000059477214,0.000587069],"study_design_scores_gemma":[0.0038590757,0.00011246817,0.9128536,0.00036837353,0.000017814737,0.0000010654304,0.00016860965,0.000080837344,0.08186062,0.00028188145,0.00014600882,0.00024968042],"about_ca_topic_score_codex":0.0007973618,"about_ca_topic_score_gemma":0.010444609,"teacher_disagreement_score":0.06983413,"about_ca_system_score_codex":0.0002753749,"about_ca_system_score_gemma":0.00065137097,"threshold_uncertainty_score":0.9553112},"labels":[],"label_agreement":null},{"id":"W4385888663","doi":"10.1016/j.euroneuro.2023.07.012","title":"Biological markers of sex-based differences in major depressive disorder and in antidepressant response","year":2023,"lang":"en","type":"review","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Ministero della Salute","keywords":"Monoaminergic; Antidepressant; Major depressive disorder; Bioinformatics; Medicine; Psychology; Neuroscience; Clinical psychology; Psychiatry; Biology; Internal medicine; Anxiety; Mood","score_opus":0.07200237302757556,"score_gpt":0.3477283573866252,"score_spread":0.27572598435904966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385888663","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5097217,0.486789,0.0000036161623,0.00012701965,0.00069354224,0.0017199205,0.00013119659,0.00023952207,0.0005745228],"genre_scores_gemma":[0.10504578,0.89402175,0.000011543664,0.00044791866,0.000049173676,0.000103774815,0.00000679587,0.00018333642,0.00012993946],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9852136,0.011186813,0.001202326,0.0014878596,0.00022861836,0.000680819],"domain_scores_gemma":[0.9939365,0.004924936,0.00054223,0.00043451152,0.000015476016,0.00014636332],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00087764213,0.00065376225,0.0017157816,0.0011365291,0.00005951839,0.000035241268,0.0009966899,0.00021084781,0.000076599266],"category_scores_gemma":[0.0014155796,0.00052225427,0.00024916156,0.001330696,0.00077288377,0.000064928194,0.00040572285,0.0009948959,0.00006637801],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015732082,0.002968281,0.0137522025,0.015334736,0.00016397885,0.020628246,0.00053249084,0.00007578608,0.059721075,0.000058784004,0.001492466,0.86953986],"study_design_scores_gemma":[0.023900198,0.0025970133,0.41978148,0.010173517,0.00032163266,0.00030005942,0.00018641875,0.0004130734,0.00038466675,0.00011209506,0.5380678,0.003762055],"about_ca_topic_score_codex":0.000009997074,"about_ca_topic_score_gemma":0.000009798924,"teacher_disagreement_score":0.8657778,"about_ca_system_score_codex":0.000027107966,"about_ca_system_score_gemma":0.00011079849,"threshold_uncertainty_score":0.9997229},"labels":[],"label_agreement":null},{"id":"W4386131673","doi":"10.1371/journal.pone.0275550","title":"Kynurenic acid, a key L-tryptophan-derived metabolite, protects the heart from an ischemic damage","year":2023,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Tel Aviv Sourasky Medical Center; Azrieli Foundation; Weizmann Institute of Science","keywords":"Kynurenic acid; Metabolite; Pharmacology; In vivo; Kynurenine; Medicine; Myocyte; Cardiac function curve; Cardioprotection; Metabolome; Heart failure; Myocardial infarction; Internal medicine; Cardiology; Chemistry; Biology; Tryptophan; Biochemistry; Glutamate receptor; Receptor","score_opus":0.06219066484053384,"score_gpt":0.26168193837233944,"score_spread":0.1994912735318056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386131673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937254,0.0001823707,0.000015086869,0.0029820139,0.00008806407,0.00080625335,0.00008712772,0.00064527243,0.0014683995],"genre_scores_gemma":[0.9955441,0.00008468123,0.00044847114,0.0026123167,0.0002125614,0.00022870667,0.00003208329,0.000057262707,0.0007798235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977053,0.00027253924,0.00022974165,0.00065424375,0.0005971425,0.00054104265],"domain_scores_gemma":[0.9986519,0.00024296023,0.00008098446,0.00082931505,0.00003599985,0.00015882842],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016982832,0.0002437984,0.0003034187,0.00010679385,0.0002989811,0.00014682637,0.0007038909,0.00010468265,0.00031412835],"category_scores_gemma":[0.00081893447,0.00018540143,0.00009969973,0.0008801567,0.00020496633,0.0003121674,0.00019502243,0.0003751611,0.001402407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044829554,0.00043801835,0.000102048645,0.000021518661,0.000030149438,0.000011873131,0.0008032556,0.000002005051,0.9975268,0.00012989194,0.0006314272,0.00025815103],"study_design_scores_gemma":[0.0006458299,0.00007191256,0.0088933725,0.00003828438,0.000028547456,0.000001329693,0.00020539423,0.0007828246,0.9859888,0.0015967286,0.0015048354,0.00024217225],"about_ca_topic_score_codex":0.000075106065,"about_ca_topic_score_gemma":0.0000316357,"teacher_disagreement_score":0.011538063,"about_ca_system_score_codex":0.00001590053,"about_ca_system_score_gemma":0.000059961847,"threshold_uncertainty_score":0.9993751},"labels":[],"label_agreement":null},{"id":"W4386154638","doi":"10.1038/s41583-023-00729-2","title":"Central regulation of stress-evoked peripheral immune responses","year":2023,"lang":"en","type":"review","venue":"Nature reviews. Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":171,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; National Alliance for Research on Schizophrenia and Depression; Canadian Institutes of Health Research; National Institute of Mental Health; Cure Alzheimer's Fund","keywords":"Immune system; Inflammation; Medicine; Neuroscience; Neutrophilia; Neuroimmunology; Sickness behavior; Immunology; Biology","score_opus":0.08220558551661725,"score_gpt":0.36970387579851915,"score_spread":0.2874982902819019,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386154638","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000043685763,0.9944435,0.00002441432,0.00007255184,0.002290003,0.002143401,0.00026365303,0.00021600582,0.00050280924],"genre_scores_gemma":[0.00030948725,0.9949088,0.000059784546,0.00031954312,0.00016582101,0.00010982978,0.00002570166,0.000104469254,0.0039965385],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9930851,0.0016578586,0.0016317652,0.0016408595,0.0010613694,0.0009230826],"domain_scores_gemma":[0.9960215,0.0008453628,0.0015352617,0.0013206092,0.00006224473,0.00021499042],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008051777,0.0007977356,0.002567155,0.00051623903,0.00028405004,0.0001463481,0.0021384389,0.0007062805,0.0000720068],"category_scores_gemma":[0.010010662,0.0005965564,0.0011920327,0.004079304,0.00071211066,0.00037619527,0.00037941887,0.001686073,0.00008511245],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031382646,0.00017387248,0.000004508018,0.026773073,0.000005718981,0.00005372755,0.00007724484,0.0000070196,0.010110153,0.0026294028,0.0018639354,0.95826995],"study_design_scores_gemma":[0.00014412915,0.00008308011,0.00030630294,0.011973737,0.000083854706,0.000060046623,0.000003590022,0.00002691105,0.0010632848,0.00009969035,0.98563546,0.0005198987],"about_ca_topic_score_codex":0.0000046078626,"about_ca_topic_score_gemma":0.000004376948,"teacher_disagreement_score":0.98377156,"about_ca_system_score_codex":0.00011830473,"about_ca_system_score_gemma":0.00053513143,"threshold_uncertainty_score":0.9996486},"labels":[],"label_agreement":null},{"id":"W4386243494","doi":"10.1101/2023.08.28.555135","title":"Ketogenic diet alters microglial morphology and changes the hippocampal lipidomic profile distinctively in stress susceptible <i>versus</i> resistant male mice upon repeated social defeat","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of British Columbia; Université Laval; University of Victoria","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología; National Institutes of Health; University of Victoria; Genome British Columbia; Université Laval","keywords":"Ketogenic diet; Hippocampal formation; Social defeat; Morphology (biology); Endocrinology; Neuroscience; Internal medicine; Biology; Physiology; Medicine; Zoology; Epilepsy","score_opus":0.03208168409250367,"score_gpt":0.24384599214454072,"score_spread":0.21176430805203705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386243494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99272937,0.00030927666,0.000017186969,0.0012864184,0.0019691945,0.001382196,0.0019118933,0.00037824558,0.000016231204],"genre_scores_gemma":[0.9979327,0.00037864922,0.00015251896,0.00033819414,0.00053916743,0.00044060472,0.000002495005,0.00017357928,0.000042113188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99538857,0.0007312633,0.0005488274,0.0018534978,0.00042795853,0.0010498918],"domain_scores_gemma":[0.99792033,0.00048017607,0.00049311516,0.0008039492,0.00012119052,0.00018125337],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006287713,0.0007161238,0.00069190416,0.00035647282,0.0004919627,0.00028056075,0.00097365456,0.00058238464,0.000056197652],"category_scores_gemma":[0.0007256497,0.00066674675,0.00017002813,0.0008415529,0.0006443132,0.00011779333,0.0011151596,0.001110041,0.00007072626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020499171,0.00013224472,0.0025306183,0.0002697254,0.000049657992,0.00018926743,0.00013234327,0.000015188659,0.9937538,0.00014112306,0.00073273544,0.0000033658432],"study_design_scores_gemma":[0.0038197832,0.0004284931,0.0750977,0.00028223594,0.00011321783,2.172739e-7,0.0001493583,0.0002151213,0.9176783,0.000010321306,0.00089970045,0.001305572],"about_ca_topic_score_codex":0.0002994107,"about_ca_topic_score_gemma":0.0005151764,"teacher_disagreement_score":0.07607553,"about_ca_system_score_codex":0.00032312475,"about_ca_system_score_gemma":0.0003547353,"threshold_uncertainty_score":0.99957836},"labels":[],"label_agreement":null},{"id":"W4386285287","doi":"10.3390/jpm13091342","title":"The Relationship of Cognitive Dysfunction with Inflammatory Markers and Carotid Intima Media Thickness in Schizophrenia","year":2023,"lang":"en","type":"article","venue":"Journal of Personalized Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Montreal Cognitive Assessment; Schizophrenia (object-oriented programming); Positive and Negative Syndrome Scale; Internal medicine; Medicine; Intima-media thickness; Cognition; Population; Cognitive impairment; Psychiatry; Gastroenterology; Psychosis; Carotid arteries","score_opus":0.02913943169564113,"score_gpt":0.2743724136323715,"score_spread":0.2452329819367304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386285287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99592614,0.00039060236,0.00006487263,0.0028543486,0.00024770977,0.00015039464,0.000002608799,0.000011991761,0.0003513527],"genre_scores_gemma":[0.9990191,0.0005261253,0.000031128217,0.00016626586,0.00011001708,0.000004511603,0.0000012566877,0.000011455329,0.00013012384],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99855787,0.00024089935,0.00038390275,0.00012451102,0.00054041995,0.00015240465],"domain_scores_gemma":[0.99504673,0.004319923,0.000358911,0.00006954304,0.00012242285,0.00008245287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011640296,0.00010385904,0.00023304699,0.000321694,0.000108037326,0.00001039335,0.00011418293,0.00005101897,0.000035252153],"category_scores_gemma":[0.007732875,0.000057813595,0.00003608281,0.00069903315,0.0008229094,0.00015056143,0.00002057427,0.00036359343,0.0000025632917],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.041911315,0.00029003975,0.603596,0.00083070336,0.00024360765,0.000898963,0.08431295,0.00012125995,0.1992225,0.022072034,0.0085655395,0.037935123],"study_design_scores_gemma":[0.012322669,0.0005499738,0.9607831,0.0015911238,0.000057827667,0.0002647492,0.020485042,0.00011027185,0.0015019733,0.0019527166,0.0002565561,0.00012399061],"about_ca_topic_score_codex":0.000007400686,"about_ca_topic_score_gemma":0.000048622074,"teacher_disagreement_score":0.35718715,"about_ca_system_score_codex":0.00002571215,"about_ca_system_score_gemma":0.00013282361,"threshold_uncertainty_score":0.9257533},"labels":[],"label_agreement":null},{"id":"W4386446485","doi":"10.20944/preprints202309.0210.v1","title":"Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Consortium canadien en neurodégénérescence associée au vieillissement; McMaster University","keywords":"Neurotrophic factors; Neuroscience; Brain-derived neurotrophic factor; Neurogenesis; Neurotrophin; Psychology; Oxidative stress; Neuroplasticity; Tangle; Alzheimer's disease; Synaptic plasticity; Medicine; Disease; Internal medicine","score_opus":0.11416409180080453,"score_gpt":0.3260974400618729,"score_spread":0.21193334826106838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386446485","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951433,0.00007223788,0.00005267102,0.00065598486,0.0014924565,0.0022250407,0.00009975956,0.00013997841,0.00011860304],"genre_scores_gemma":[0.99902755,0.00014376061,0.000016239695,0.0003500342,0.000030094769,0.00026198121,0.000005606835,0.00008767425,0.000077065015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99620783,0.0005585654,0.00066072,0.0013275426,0.0008218597,0.00042347057],"domain_scores_gemma":[0.9963754,0.0009494837,0.0006094877,0.0018547487,0.000047209658,0.0001636957],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019603243,0.00047301492,0.00063158164,0.00030821562,0.000090595706,0.0000139801705,0.0016015576,0.00028233373,0.000111301124],"category_scores_gemma":[0.0034268014,0.00038357518,0.00043653257,0.00040004656,0.00021901018,0.00006682557,0.0029515289,0.00086234626,0.00013199857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004054343,0.00047705334,0.009241608,0.0006540426,0.0000120055565,0.00003399326,0.0005735972,0.0025689513,0.98531497,0.00045494334,0.000016931855,0.0002464768],"study_design_scores_gemma":[0.00042488318,0.000024501167,0.37802774,0.0011035255,0.000022910122,1.7781655e-7,0.000011312376,0.00010594621,0.61269003,0.0073887147,0.0000050871727,0.00019520224],"about_ca_topic_score_codex":0.0000668062,"about_ca_topic_score_gemma":0.000007347426,"teacher_disagreement_score":0.37262496,"about_ca_system_score_codex":0.000041244497,"about_ca_system_score_gemma":0.00019037034,"threshold_uncertainty_score":0.9998616},"labels":[],"label_agreement":null},{"id":"W4386505124","doi":"10.1111/pcn.13596","title":"Human <i>in vivo</i> evidence of reduced astrocyte activation and neuroinflammation in patients with treatment‐resistant depression following electroconvulsive therapy","year":2023,"lang":"en","type":"article","venue":"Psychiatry and Clinical Neurosciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Glial fibrillary acidic protein; Astrocyte; Neuroinflammation; Internal medicine; Psychology; Depression (economics); Medicine; Oncology; Central nervous system; Inflammation; Immunohistochemistry","score_opus":0.03736289839923788,"score_gpt":0.3349959326024188,"score_spread":0.2976330342031809,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386505124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989392,0.000037880294,0.000002807238,0.0002925869,0.00024497055,0.00040247245,0.0000017342584,0.000030245828,0.0000480763],"genre_scores_gemma":[0.9994519,0.00033365662,0.000026192884,0.0001260384,0.000017133618,0.000015284177,5.353343e-7,0.0000078417725,0.00002144136],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99825,0.00025536344,0.00040996916,0.00058960065,0.00026153776,0.00023349213],"domain_scores_gemma":[0.9991232,0.0004758456,0.00019102049,0.0001371335,0.0000105775225,0.00006222747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002477532,0.00013956294,0.00021195025,0.00016186445,0.00015700504,0.00004861997,0.0001313276,0.000048419144,0.000002201746],"category_scores_gemma":[0.00032530908,0.00010023019,0.000046225774,0.0007688039,0.00020348607,0.0004697507,0.000030266465,0.00012170467,4.4712124e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005277192,0.0003113623,0.626177,0.000011199994,0.0000011425265,0.0000019329666,0.000045053024,0.000012065859,0.3711536,0.000061140665,0.0000023027462,0.0016954773],"study_design_scores_gemma":[0.0022686315,0.0026177359,0.9410802,0.00014618564,0.0000030958172,3.5680628e-7,0.00006826475,0.00015879552,0.053360928,0.0001848437,0.0000061939168,0.000104766965],"about_ca_topic_score_codex":0.000018371038,"about_ca_topic_score_gemma":0.000060390717,"teacher_disagreement_score":0.31779265,"about_ca_system_score_codex":0.000007819877,"about_ca_system_score_gemma":0.00004798445,"threshold_uncertainty_score":0.40872684},"labels":[],"label_agreement":null},{"id":"W4386521941","doi":"10.1016/j.bbi.2023.09.006","title":"Ketogenic diet changes microglial morphology and the hippocampal lipidomic profile differently in stress susceptible versus resistant male mice upon repeated social defeat","year":2023,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; McGill University; University of British Columbia; Université Laval; University of Victoria","funders":"National Institute of Mental Health; Fonds de Recherche du Québec - Santé; Academy of Finland; Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología; Canada Research Chairs; University of Victoria","keywords":"Microglia; Hippocampal formation; Inflammation; Chronic stress; Central nervous system; Ketogenic diet; Hippocampus; Parenchyma; Population; Physiology; Psychology; Endocrinology; Internal medicine; Medicine; Neuroscience; Pathology; Epilepsy","score_opus":0.04036767976677574,"score_gpt":0.2841792742982712,"score_spread":0.24381159453149548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386521941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99700385,0.00015204278,3.6394164e-7,0.0012874809,0.00035326392,0.0006785483,0.00026267878,0.00009894652,0.00016280345],"genre_scores_gemma":[0.9985284,0.00021050277,0.0000068520067,0.00019459649,0.000066480905,0.00015664232,0.00006524324,0.000027965421,0.0007432665],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99779934,0.0008366165,0.00024063681,0.00044452402,0.0001705766,0.0005082858],"domain_scores_gemma":[0.99883693,0.0007031968,0.00009647453,0.00027510762,0.000020627178,0.00006764017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040720866,0.0002413982,0.00031911454,0.00017152933,0.00057474495,0.00009765016,0.00031897248,0.0001636176,0.0001106819],"category_scores_gemma":[0.0003661295,0.00019241392,0.00007666582,0.000440869,0.00066707085,0.00008496597,0.00034072282,0.00041254523,0.000018376131],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005786812,0.0001826828,0.005317255,0.000036272522,0.000007621671,0.000053015297,0.0029942477,2.1920748e-7,0.98243594,0.00017318504,0.0006038389,0.002408926],"study_design_scores_gemma":[0.02458236,0.001314554,0.7540267,0.00005573461,0.00010249409,0.00007026521,0.009678556,0.000093971925,0.208736,0.00019583822,0.0003667726,0.00077674416],"about_ca_topic_score_codex":0.0006011243,"about_ca_topic_score_gemma":0.0016279881,"teacher_disagreement_score":0.77369994,"about_ca_system_score_codex":0.00004101653,"about_ca_system_score_gemma":0.00003381412,"threshold_uncertainty_score":0.78464115},"labels":[],"label_agreement":null},{"id":"W4386606831","doi":"10.1038/s41380-023-02246-1","title":"Prefrontal cortex astroglia modulate anhedonia-like behavior","year":2023,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; Campbell Family Mental Health Research Institute; National Institutes of Health; Government of Canada; U.S. Department of Health and Human Services; Yale University; Centre for Addiction and Mental Health; Brain and Behavior Research Foundation; National Alliance for Research on Schizophrenia and Depression","keywords":"Anhedonia; Glial fibrillary acidic protein; Prefrontal cortex; Neuroscience; Astrogliosis; Psychology; Diphtheria toxin; Chronic stress; Biology; Medicine; Central nervous system; Internal medicine; Toxin; Immunohistochemistry; Cognition; Dopamine","score_opus":0.013484675672101674,"score_gpt":0.2576114785422362,"score_spread":0.24412680287013452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386606831","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928978,0.00011522292,0.0003713306,0.0006397547,0.0023746795,0.00039316877,0.000041255513,0.0006148836,0.0025518837],"genre_scores_gemma":[0.9956124,0.000014621053,0.0007465971,0.0018840603,0.00007782535,0.00007676503,0.000021112459,0.000068948946,0.0014977007],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99801046,0.00008862685,0.00024098669,0.0006751118,0.0004141446,0.00057065947],"domain_scores_gemma":[0.9991888,0.000016587826,0.000074581876,0.000541757,0.000015104292,0.0001632034],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000076519456,0.00024677158,0.00017690401,0.00016699532,0.00017219655,0.00007615336,0.0004361201,0.000093644754,0.00015335288],"category_scores_gemma":[0.000035291414,0.0002531837,0.00019283734,0.0006551144,0.00011596189,0.000116569354,0.00013089059,0.00022618976,0.0013625432],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003647398,0.0002746033,0.0046488238,0.000022956556,0.000011206721,0.00026794613,0.00008404669,0.0000931822,0.9819951,0.0030874915,0.006670977,0.0028072088],"study_design_scores_gemma":[0.004594252,0.00065142073,0.7826814,0.00008309611,0.000098338554,0.00024160041,0.0004585523,0.0030106811,0.18075651,0.0086020585,0.016979003,0.0018430776],"about_ca_topic_score_codex":0.000012890535,"about_ca_topic_score_gemma":0.00001785369,"teacher_disagreement_score":0.8012386,"about_ca_system_score_codex":0.00002205726,"about_ca_system_score_gemma":0.000074406125,"threshold_uncertainty_score":0.999992},"labels":[],"label_agreement":null},{"id":"W4386718928","doi":"10.21203/rs.3.rs-3346140/v1","title":"Decoding the Inflammatory Signature of the Major Depressive Episode: Insights from Peripheral Immunophenotyping in Active and Remitted Condition","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"FOXP3; Inflammation; Immune system; Immunophenotyping; Major depressive episode; Immunology; Pathogenesis; Acquired immune system; Medicine; Internal medicine; Flow cytometry","score_opus":0.045644553332728904,"score_gpt":0.33935179304611846,"score_spread":0.2937072397133895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386718928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955478,0.001304295,0.000016766764,0.00086752453,0.0002892127,0.0014200415,0.00018402816,0.000051724637,0.00031864506],"genre_scores_gemma":[0.9990972,0.00031069276,0.0000140519005,0.00008771288,0.000090834874,0.00021088363,0.000029992845,0.00004270285,0.0001159153],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.995879,0.0017628977,0.000339188,0.00071640284,0.00087570114,0.00042682744],"domain_scores_gemma":[0.9961507,0.0026757647,0.00022289311,0.0007316025,0.00015921188,0.000059851936],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00036440438,0.00023900386,0.00028990186,0.00026889672,0.0005155672,0.00015008627,0.0009744171,0.00038376916,0.000044398534],"category_scores_gemma":[0.0029605164,0.0001530859,0.00011832562,0.00066955417,0.00074365165,0.00015611762,0.0018722267,0.0028189286,0.000007787511],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006540115,0.00014668705,0.0082332995,0.0009277588,0.00011017644,0.0001267506,0.026109725,0.0014143188,0.95153636,0.0041912235,0.0008786293,0.005671052],"study_design_scores_gemma":[0.0014212712,0.00005015291,0.5749193,0.0029849247,0.000014498143,0.0000026522916,0.006770037,0.0035847768,0.33804697,0.07160415,0.00018648434,0.00041481032],"about_ca_topic_score_codex":0.0007206083,"about_ca_topic_score_gemma":0.0008721065,"teacher_disagreement_score":0.6134894,"about_ca_system_score_codex":0.00019433304,"about_ca_system_score_gemma":0.0002532156,"threshold_uncertainty_score":0.9994816},"labels":[],"label_agreement":null},{"id":"W4386800579","doi":"10.1093/neuonc/noad174","title":"Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute; Cannonball Kids' cancer Foundation; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Medicine; Temozolomide; Internal medicine; Immunotherapy; Oncology; Gastroenterology; Radiation therapy; Chemotherapy; Glioma; Cancer; Cancer research","score_opus":0.033341433046735265,"score_gpt":0.32507363542328427,"score_spread":0.291732202376549,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386800579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891031,0.000035273097,0.00012867551,0.0065364027,0.0008448079,0.0025673702,0.00007659638,0.0003758246,0.0003319977],"genre_scores_gemma":[0.98611873,0.00007037728,0.00010456626,0.012072742,0.0006623766,0.00077352015,0.000032826378,0.000085260814,0.00007961189],"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99726874,0.00034195368,0.00052457955,0.00082364416,0.0002642379,0.0007768495],"domain_scores_gemma":[0.9953941,0.0038363102,0.00021812483,0.00040207588,0.000025030347,0.00012437283],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044157673,0.00028988716,0.00048016538,0.0005877352,0.00019530587,0.00004798189,0.0005947848,0.00022862101,0.00011476837],"category_scores_gemma":[0.0025199591,0.00029125897,0.00022589006,0.0014131458,0.00014898818,0.000120229204,0.00007252637,0.00036340975,0.00017316882],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.046991758,0.0040866486,0.0027504915,0.000075219046,0.000015301775,0.00030462857,0.0010688727,0.00046642506,0.8640423,0.00061343337,0.043413315,0.036171623],"study_design_scores_gemma":[0.5850566,0.01587244,0.0044331723,0.00001732891,0.00003208718,0.00007510558,0.00011469328,0.007475038,0.22740604,0.0024332728,0.15585783,0.0012263719],"about_ca_topic_score_codex":0.000013985259,"about_ca_topic_score_gemma":0.000026737802,"teacher_disagreement_score":0.63663626,"about_ca_system_score_codex":0.00011396542,"about_ca_system_score_gemma":0.00044010507,"threshold_uncertainty_score":0.9999539},"labels":[],"label_agreement":null},{"id":"W4386913032","doi":"10.1007/s00213-023-06466-9","title":"Frontostriatal circuitry and the tryptophan kynurenine pathway in major psychiatric disorders","year":2023,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Western University","funders":"","keywords":"Neurocognitive; Kynurenine pathway; Bipolar disorder; Kynurenine; Psychology; Schizophrenia (object-oriented programming); Psychiatry; Prefrontal cortex; Cognition; Major depressive disorder; Neuroscience; Functional magnetic resonance imaging; Ventrolateral prefrontal cortex; Clinical psychology; Tryptophan","score_opus":0.014542661824212072,"score_gpt":0.2808309174909835,"score_spread":0.2662882556667714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386913032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97591686,0.0007578269,0.000036379282,0.0119642755,0.0027021791,0.0008782882,0.000033484204,0.00025831952,0.007452378],"genre_scores_gemma":[0.99392205,0.0011951694,0.000019833227,0.0036722117,0.00022944924,0.00021312706,0.00000642168,0.00003578313,0.0007059684],"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9976577,0.0004499137,0.00037231995,0.0006725355,0.0002196814,0.0006278523],"domain_scores_gemma":[0.9987483,0.0007472258,0.00011009224,0.00026677642,0.000008735214,0.00011885374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003962511,0.00025154726,0.00030795106,0.00037973892,0.00021822476,0.000042229127,0.00049571577,0.00013425665,0.0003821382],"category_scores_gemma":[0.00021752715,0.00018970079,0.00010967227,0.0014890446,0.0005274341,0.00012887215,0.00011269593,0.00043014862,0.00030894054],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009918264,0.0014071281,0.010742169,0.00021440774,0.00012164836,0.00024018317,0.0067298664,0.00017572168,0.60998595,0.032072864,0.10197572,0.22641607],"study_design_scores_gemma":[0.2923911,0.0011164751,0.23345464,0.000059087684,0.00014529977,0.00024657234,0.0034909393,0.009603566,0.047706574,0.20628959,0.20195028,0.0035458775],"about_ca_topic_score_codex":0.00004582735,"about_ca_topic_score_gemma":0.0001459506,"teacher_disagreement_score":0.5622794,"about_ca_system_score_codex":0.000022078684,"about_ca_system_score_gemma":0.000046967773,"threshold_uncertainty_score":0.7735774},"labels":[],"label_agreement":null},{"id":"W4386984436","doi":"10.17305/bb.2023.9690","title":"Exploring the clinical characteristics and etiological factors of comorbid major depressive disorder and social anxiety disorder","year":2023,"lang":"en","type":"article","venue":"Biomolecules and Biomedicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Comorbidity; Major depressive disorder; Beck Anxiety Inventory; Medicine; Beck Depression Inventory; Clinical psychology; Anxiety; Biomarker; Internal medicine; Toronto Alexithymia Scale; Psychiatry; Etiology; Systemic inflammation; Psychology; Mood; Inflammation","score_opus":0.10978540780047241,"score_gpt":0.3262280924205508,"score_spread":0.21644268462007837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386984436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963193,0.0002211779,0.0000639235,0.0028436966,0.00017543088,0.00018825008,0.000115672585,0.000048504033,0.000024057632],"genre_scores_gemma":[0.9953422,0.0041146837,0.000010682265,0.00035757353,0.00009206081,0.000012460136,0.000031341653,0.000011647504,0.000027373542],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988382,0.000118489384,0.00029417145,0.0003529961,0.00016666735,0.00022947986],"domain_scores_gemma":[0.99929005,0.00039727823,0.00010779697,0.00010723711,0.000019572823,0.000078063174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019068793,0.0001597949,0.00027411833,0.00007697172,0.00025737993,0.000027756952,0.0001160443,0.000075986696,0.000010499583],"category_scores_gemma":[0.00030249945,0.00008851631,0.00004228729,0.00029975487,0.0013841386,0.000057877412,0.00021130563,0.00012797122,0.0000017534115],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003043993,0.00034456648,0.41993558,0.00022998311,0.00006459803,0.000042735443,0.0030815091,6.971232e-8,0.35075262,0.0034525916,0.00071367994,0.22107765],"study_design_scores_gemma":[0.0011038196,0.0002978317,0.986454,0.000027338452,0.00002568633,0.000011782806,0.0015472021,0.00011084207,0.0028110386,0.00016247931,0.0072861784,0.00016180667],"about_ca_topic_score_codex":0.000034501743,"about_ca_topic_score_gemma":0.0000057610773,"teacher_disagreement_score":0.5665184,"about_ca_system_score_codex":0.0000024012018,"about_ca_system_score_gemma":0.000009642404,"threshold_uncertainty_score":0.50999165},"labels":[],"label_agreement":null},{"id":"W4387023707","doi":"10.1038/s41380-023-02247-0","title":"Smoking, tobacco dependence, and neurometabolites in the dorsal anterior cingulate cortex","year":2023,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse","keywords":"Creatine; Neuroinflammation; Choline; Anterior cingulate cortex; Medicine; Smoking cessation; Internal medicine; Nicotine; Craving; Psychology; Endocrinology; Addiction; Inflammation; Psychiatry; Pathology; Cognition","score_opus":0.011411779567000409,"score_gpt":0.25580758363540534,"score_spread":0.24439580406840494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387023707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948412,0.000815011,0.000030612322,0.0017357522,0.0006720626,0.00022533086,0.000006906253,0.0001231893,0.0015499468],"genre_scores_gemma":[0.9941104,0.00013347254,0.00006395435,0.005545414,0.000034377787,0.000017948094,0.0000017993692,0.0000248352,0.00006781304],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99844867,0.00018472318,0.00020880767,0.0004707207,0.00030814932,0.00037891493],"domain_scores_gemma":[0.9994597,0.000078030316,0.00005837697,0.0003522105,0.000007293192,0.000044417768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021784326,0.00016833996,0.00014892097,0.00022906854,0.00012387296,0.00013282229,0.00040759848,0.000052944775,0.000026238042],"category_scores_gemma":[0.00015250809,0.00013055372,0.00007283012,0.0010924687,0.000111191686,0.0000957258,0.000104720086,0.00022817162,0.000047790312],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009146985,0.00029268273,0.1958163,0.00008927688,0.000019799927,0.0011336998,0.001419855,0.00007675704,0.75409615,0.029021926,0.0018781526,0.016063942],"study_design_scores_gemma":[0.0009969682,0.00008080949,0.97888386,0.000048249567,0.00001128043,0.00013530994,0.00039934646,0.00030228042,0.007938045,0.0083673,0.0025190264,0.00031753804],"about_ca_topic_score_codex":0.00002660138,"about_ca_topic_score_gemma":0.000032967404,"teacher_disagreement_score":0.7830676,"about_ca_system_score_codex":0.0000043641653,"about_ca_system_score_gemma":0.000032771724,"threshold_uncertainty_score":0.5323826},"labels":[],"label_agreement":null},{"id":"W4387062081","doi":"10.1016/j.lfs.2023.122102","title":"EPO prevents neuroinflammation and relieves depression via JAK/STAT signaling","year":2023,"lang":"en","type":"article","venue":"Life Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Science, Technology and Innovation Commission of Shenzhen Municipality; Guangdong Medical Research Foundation","keywords":"Erythropoietin; Neuroinflammation; Ruxolitinib; Pharmacology; Cytokine; Medicine; Behavioural despair test; Tail suspension test; Antidepressant; Inflammation; Immunology; Endocrinology; Hippocampus; Myelofibrosis; Bone marrow","score_opus":0.03949660195593874,"score_gpt":0.2878116476827611,"score_spread":0.24831504572682234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387062081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99705976,0.000076869954,0.00017930254,0.00073666184,0.00026589874,0.00014260258,0.0000018713613,0.0001800291,0.0013570014],"genre_scores_gemma":[0.99891055,0.00011879064,0.00018821101,0.00042442488,0.000045521538,0.000007651793,8.8066236e-7,0.000006552917,0.00029741842],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986501,0.0001021842,0.00016176108,0.00042832116,0.00039252904,0.00026511963],"domain_scores_gemma":[0.9994248,0.00028151504,0.00007856195,0.00010835744,0.000007969108,0.00009875647],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032628007,0.00009279578,0.00008281702,0.00014176648,0.000480608,0.00010688446,0.00025210687,0.0000310634,0.000029226137],"category_scores_gemma":[0.00080483116,0.000073628544,0.000024816369,0.00080219406,0.00028216164,0.0004555606,0.00011767251,0.000067859604,0.000096499556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009394199,0.000016173259,0.0050698114,0.000020297448,7.0499794e-7,0.0000086226155,0.0005456312,0.00065882475,0.9816209,0.000320732,0.0007370538,0.01099184],"study_design_scores_gemma":[0.0005885751,0.00018151819,0.064344235,0.000102316066,0.0000057211773,0.000021359394,0.0006900819,0.033925485,0.88201666,0.015376771,0.0023343307,0.00041292864],"about_ca_topic_score_codex":0.000009292986,"about_ca_topic_score_gemma":0.0000029640507,"teacher_disagreement_score":0.099604234,"about_ca_system_score_codex":0.0000038652124,"about_ca_system_score_gemma":0.000035124816,"threshold_uncertainty_score":0.36964968},"labels":[],"label_agreement":null},{"id":"W4387328837","doi":"10.1038/s41537-023-00398-1","title":"Inflammatory markers of symptomatic remission at 6 months in patients with first-episode schizophrenia","year":2023,"lang":"en","type":"article","venue":"Schizophrenia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"dup; Internal medicine; Schizophrenia (object-oriented programming); Positive and Negative Syndrome Scale; Psychosis; Depression (economics); Biomarker; Beck Depression Inventory; Psychology; Psychiatry; Medicine; Gastroenterology; Anxiety","score_opus":0.008633100402635301,"score_gpt":0.2136582503770875,"score_spread":0.2050251499744522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387328837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99753565,0.00003039918,0.0000028414797,0.00017656694,0.00019778975,0.00063491217,0.000030956147,0.0002791894,0.0011116753],"genre_scores_gemma":[0.99908876,0.000039520983,0.00028695937,0.00007458786,0.00002513073,0.00005132647,0.000019952993,0.000060365608,0.00035337056],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974407,0.00014993316,0.0005273039,0.0006262203,0.0007001934,0.0005556514],"domain_scores_gemma":[0.9985452,0.00038737382,0.00024796007,0.0006050427,0.000040059636,0.00017434696],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020979201,0.00032039787,0.00036857225,0.0005028423,0.00018828806,0.000029296472,0.00047830475,0.00013816888,0.00016447502],"category_scores_gemma":[0.00064817,0.00026804334,0.00009716122,0.001391616,0.00022967866,0.00032083632,0.000250718,0.00023129523,0.00032602422],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.027876012,0.0008225188,0.8975255,0.0011685337,0.00006335329,0.00015286135,0.00118271,0.0018834438,0.04077215,0.001892521,0.012232425,0.014427975],"study_design_scores_gemma":[0.008131947,0.0002849144,0.9646123,0.0005270024,0.000011022776,0.0000023672076,0.000045377088,0.0009765825,0.02384736,0.00060246,0.00048543565,0.00047320453],"about_ca_topic_score_codex":0.000030936124,"about_ca_topic_score_gemma":0.00049175357,"teacher_disagreement_score":0.06708683,"about_ca_system_score_codex":0.0001046814,"about_ca_system_score_gemma":0.000077090954,"threshold_uncertainty_score":0.9999772},"labels":[],"label_agreement":null},{"id":"W4387497114","doi":"10.1016/j.euroneuro.2023.08.075","title":"EARLY LIFE ADVERSITY AND SOCIAL WITHDRAWAL BEHAVIOR – IDENTIFYING RISK FOR ADULT PSYCHOPATHOLOGY USING A TRANSLATIONAL MODEL AND EXPRESSION-BASED POLYGENIC SCORES.","year":2023,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Anxiety; Psychopathology; Psychology; Genome-wide association study; Clinical psychology; Social anxiety; Cohort; Bipolar disorder; Depression (economics); Mood; Psychiatry; Medicine; Gene; Single-nucleotide polymorphism; Genetics; Biology; Internal medicine; Genotype","score_opus":0.0482753722797429,"score_gpt":0.32102527926900293,"score_spread":0.27274990698926005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387497114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946014,0.000040529707,0.002826116,0.00059295504,0.00060889724,0.00065647834,0.0001946822,0.00038184572,0.00009708061],"genre_scores_gemma":[0.9949182,0.00007839384,0.0006068173,0.0039956113,0.00018320684,0.000030127347,0.000008599362,0.00011434864,0.00006464178],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99720967,0.0007688249,0.00034976803,0.0009303415,0.00021405554,0.00052732247],"domain_scores_gemma":[0.9990478,0.00032399778,0.00020784794,0.00015525868,0.00006581734,0.00019925513],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026606905,0.00028429888,0.0002600957,0.0003227204,0.0007134301,0.000069415226,0.0002851272,0.00008455706,0.000020526546],"category_scores_gemma":[0.00019105658,0.00030503553,0.000119044365,0.00034312034,0.0004655635,0.00019347647,0.000108236614,0.00035991165,0.000019775985],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012195683,0.00012552083,0.0030615444,0.000043329233,0.0000083575815,0.0001617576,0.00093893526,0.0010688987,0.9907999,0.00008538642,0.0008000837,0.0016866904],"study_design_scores_gemma":[0.026117012,0.00057417154,0.7763901,0.00003822083,0.00030893725,0.00013929454,0.00017773661,0.18786073,0.0059752683,0.00060179544,0.00054829067,0.0012684528],"about_ca_topic_score_codex":0.0000041064386,"about_ca_topic_score_gemma":0.0000023755915,"teacher_disagreement_score":0.98482466,"about_ca_system_score_codex":0.000010073532,"about_ca_system_score_gemma":0.00006147223,"threshold_uncertainty_score":0.99994016},"labels":[],"label_agreement":null},{"id":"W4387501546","doi":"10.1016/j.euroneuro.2023.08.329","title":"T44. MECHANISTIC CONVERGENCE OF DEPRESSION AND SUICIDALITY ON ASTROCYTE FATTY ACID SIGNALLING","year":2023,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Genome-wide association study; Major depressive disorder; Transcriptome; Mendelian randomization; Computational biology; Biology; Gene; Genetics; Neuroscience; Gene expression; Single-nucleotide polymorphism; Genotype; Cognition; Genetic variants","score_opus":0.03810933532534466,"score_gpt":0.30377673189985416,"score_spread":0.2656673965745095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387501546","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929859,0.000039139944,0.0005708626,0.00021500533,0.0011129819,0.0002764526,0.000023672419,0.0004752504,0.0043007014],"genre_scores_gemma":[0.9970128,0.00027233458,0.000057500158,0.002339253,0.00009306514,0.000007964666,0.000002609586,0.00007673087,0.00013775243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99707454,0.0010633031,0.00037284082,0.0007818676,0.0002665902,0.00044084867],"domain_scores_gemma":[0.99887365,0.00046582866,0.00018976703,0.00026714988,0.000031268046,0.00017233875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035680298,0.00024201581,0.00024522806,0.0002034772,0.00014894495,0.000023128681,0.0004385374,0.000041386927,0.00017260361],"category_scores_gemma":[0.00037226808,0.00022881324,0.00007338719,0.0005498306,0.00025500092,0.000081357524,0.00021902283,0.00032451784,0.00039438164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003797446,0.000087203676,0.00028986367,0.000036753914,0.000005679247,0.00027580862,0.000108044784,0.00018325438,0.99403906,0.0004022041,0.0008683966,0.003323968],"study_design_scores_gemma":[0.0019912017,0.00046997392,0.06216957,0.00002932327,0.00001726931,0.00003306298,0.000032573986,0.0017081787,0.93132275,0.0002789935,0.001665941,0.00028115232],"about_ca_topic_score_codex":0.0000017356341,"about_ca_topic_score_gemma":4.3812165e-7,"teacher_disagreement_score":0.06271632,"about_ca_system_score_codex":0.000009476852,"about_ca_system_score_gemma":0.00001693129,"threshold_uncertainty_score":0.93307334},"labels":[],"label_agreement":null},{"id":"W4387502938","doi":"10.1093/pnasnexus/pgad299","title":"Ribosomal dysregulation: A conserved pathophysiological mechanism in human depression and mouse chronic stress","year":2023,"lang":"en","type":"article","venue":"PNAS Nexus","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Major depressive disorder; Transcriptome; Mechanism (biology); Phenotype; Pseudogene; Ribosomal protein; Biology; Gene; Neuroscience; Psychology; Bioinformatics; Ribosome; Genetics; Mood; Gene expression; Psychiatry; RNA","score_opus":0.0333625215937912,"score_gpt":0.27463062535278643,"score_spread":0.2412681037589952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387502938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99888515,0.000052111653,0.000025847969,0.00011906925,0.00007966757,0.00021221588,0.000016271459,0.0002100298,0.00039965214],"genre_scores_gemma":[0.9992787,0.000026414331,0.00001697033,0.00019176977,0.000050444083,0.000035830562,0.000013085561,0.0000137038205,0.00037305415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887687,0.00010414142,0.00015755938,0.00041893497,0.00015574435,0.00028673513],"domain_scores_gemma":[0.99955076,0.0001445666,0.000046396446,0.00018237541,0.000007761312,0.000068125366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006901691,0.00012624204,0.00014286498,0.00009533621,0.00015700462,0.00003956151,0.00014992637,0.0000910938,0.00006093233],"category_scores_gemma":[0.00013524955,0.00010860224,0.00003221995,0.00030832403,0.00010559877,0.000102025246,0.00015524523,0.00013111335,0.000041458217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019771293,0.00005024901,0.0006047111,0.000021553362,8.8737943e-7,0.00006401886,0.0001779227,0.00015190887,0.99221814,0.0057330457,0.00006477726,0.00089304725],"study_design_scores_gemma":[0.0018197264,0.00018166557,0.09179359,0.000053576307,0.000002740451,0.0000086917225,0.00016629261,0.009706713,0.8528978,0.04301769,0.000073783725,0.00027773558],"about_ca_topic_score_codex":0.000022869644,"about_ca_topic_score_gemma":0.000049790655,"teacher_disagreement_score":0.13932031,"about_ca_system_score_codex":0.000025199466,"about_ca_system_score_gemma":0.000019848514,"threshold_uncertainty_score":0.44286707},"labels":[],"label_agreement":null},{"id":"W4387675632","doi":"10.1016/j.neubiorev.2023.105425","title":"Major depressive disorder as a neuro-immune disorder: Origin, mechanisms, and therapeutic opportunities","year":2023,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":73,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Universidade do Extremo Sul Catarinense; Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Neuroinflammation; Major depressive disorder; Inflammation; Antidepressant; Pathophysiology; Systemic inflammation; Neuroscience; Immune system; Mechanism (biology); Medicine; Sickness behavior; Psychoneuroimmunology; Psychology; Immunology; Bioinformatics; Biology; Amygdala; Internal medicine; Hippocampus","score_opus":0.2331093375326192,"score_gpt":0.39352735622229174,"score_spread":0.16041801868967254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387675632","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002885332,0.99239343,0.00010726862,0.000056488363,0.0016153652,0.0045835855,0.00020904212,0.0005503816,0.00019588413],"genre_scores_gemma":[0.00010723877,0.9932173,0.00004998,0.0024292157,0.00007531791,0.0014348705,0.000031017313,0.00029287545,0.0023622173],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.991538,0.0011100182,0.0019216731,0.0028039892,0.0011131144,0.0015131901],"domain_scores_gemma":[0.9962142,0.00009811417,0.0014028404,0.0016591166,0.00005732917,0.0005684069],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0007045716,0.0016944674,0.0032640793,0.0007273902,0.0010833459,0.000735063,0.0024093282,0.00047217385,0.00021181931],"category_scores_gemma":[0.0015350383,0.0012705332,0.0010923902,0.002257111,0.001335476,0.0005443465,0.001024341,0.0012374969,0.0007471688],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006364943,0.00020208352,0.000006385628,0.0028900353,4.496532e-7,0.00022017375,0.000049927985,2.1848273e-7,0.0012304629,0.002825285,0.000277149,0.99229145],"study_design_scores_gemma":[0.00036803578,0.0003618123,0.000022853215,0.0029390636,0.00044501456,0.00032604308,0.000063965446,0.000015480613,0.000025004392,0.00061938947,0.99357,0.0012432882],"about_ca_topic_score_codex":0.00012141113,"about_ca_topic_score_gemma":0.000031898133,"teacher_disagreement_score":0.9932929,"about_ca_system_score_codex":0.0000755172,"about_ca_system_score_gemma":0.0005046204,"threshold_uncertainty_score":0.9995802},"labels":[],"label_agreement":null},{"id":"W4387764565","doi":"10.1017/s1478951523001438","title":"Biomarkers use in psycho-oncology practice: Are we there yet?","year":2023,"lang":"en","type":"article","venue":"Palliative & Supportive Care","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; St Mary's Hospital Centre; HEC Montréal; Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Content (measure theory); Action (physics); Medicine; Psychology; Oncology; Mathematics","score_opus":0.10452399893021606,"score_gpt":0.38937583341393817,"score_spread":0.2848518344837221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387764565","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96209264,0.0007100487,0.000067733934,0.013276833,0.0011263905,0.0013005721,0.0005268891,0.00046824967,0.020430673],"genre_scores_gemma":[0.9948958,0.0014819419,0.00012952172,0.00254106,0.000042871176,0.0001521468,0.000045467397,0.000050992403,0.0006602121],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99707705,0.0006306404,0.00038821844,0.0008478807,0.0003961261,0.00066010485],"domain_scores_gemma":[0.9968777,0.0020491285,0.00036919065,0.00034589702,0.00020388461,0.00015422676],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020993472,0.00030113285,0.000341786,0.0003189893,0.0001438625,0.00007452934,0.00035730202,0.00017966886,0.00034808347],"category_scores_gemma":[0.0045142504,0.00027462083,0.00014036553,0.0016238136,0.00029601672,0.00052914,0.00013843528,0.00038123093,0.0007228886],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022639935,0.0012412029,0.58989376,0.0006087906,0.00023175072,0.008096223,0.14616995,0.00015281803,0.08423853,0.005650322,0.12887299,0.03257967],"study_design_scores_gemma":[0.0030705917,0.0005160225,0.5245963,0.00029942096,0.00002933437,0.000010500051,0.30188978,0.00012147416,0.0316944,0.0016088821,0.13532378,0.0008395299],"about_ca_topic_score_codex":0.00006048576,"about_ca_topic_score_gemma":0.0005251943,"teacher_disagreement_score":0.15571985,"about_ca_system_score_codex":0.00027805023,"about_ca_system_score_gemma":0.00018999517,"threshold_uncertainty_score":0.9999706},"labels":[],"label_agreement":null},{"id":"W4387807610","doi":"10.1016/j.atherosclerosis.2023.117344","title":"Tryptophan metabolites and incident cardiovascular disease: The EPIC-Norfolk prospective population study","year":2023,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Diabetes Fonds; Dehcho First Nations; National Heart, Lung, and Blood Institute; Hartstichting; ZonMw; Fondation Leducq","keywords":"Kynurenine; Medicine; Hazard ratio; Proportional hazards model; Prospective cohort study; Internal medicine; Tryptophan; Kynurenine pathway; Cohort; Disease; Cohort study; Population; EPIC; Endocrinology; Physiology; Biology; Confidence interval; Environmental health; Biochemistry; Amino acid","score_opus":0.03521394523905484,"score_gpt":0.25803060131303435,"score_spread":0.2228166560739795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387807610","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972747,0.00055039546,0.00001910274,0.0003419294,0.00019879556,0.0011554852,0.000022795028,0.00030280813,0.000133986],"genre_scores_gemma":[0.99872607,0.0003683433,0.0000104015935,0.00023617162,0.00008747637,0.00027745237,0.000004117227,0.000039996037,0.00024998054],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99781865,0.0003556058,0.00022005856,0.0006586142,0.0005970949,0.00035000092],"domain_scores_gemma":[0.9989117,0.00023205506,0.00006791665,0.0006393802,0.00002620477,0.00012277716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042093426,0.00022082428,0.00025871737,0.00009561605,0.0005234129,0.00017097317,0.00029733294,0.000040105333,0.000033063683],"category_scores_gemma":[0.00052089954,0.00015485354,0.00020544245,0.0008844796,0.00013534227,0.00022256795,0.00019613828,0.00013267458,0.00009731573],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000096036245,0.0005642173,0.9141932,0.00003939564,0.00030278467,0.000018803514,0.007280496,0.0005194358,0.05207176,0.0060928855,0.0003036116,0.018517355],"study_design_scores_gemma":[0.0007113742,0.000061584826,0.98963845,0.000009965512,0.00008645088,9.2892566e-7,0.0009477101,0.00021521862,0.005180988,0.0024185197,0.0005352859,0.00019354385],"about_ca_topic_score_codex":0.0002806981,"about_ca_topic_score_gemma":0.000029889492,"teacher_disagreement_score":0.07544521,"about_ca_system_score_codex":0.00003373414,"about_ca_system_score_gemma":0.000015004103,"threshold_uncertainty_score":0.6314744},"labels":[],"label_agreement":null},{"id":"W4388046979","doi":"10.3389/fphar.2023.1276309","title":"Ketamine promptly normalizes excess norepinephrine and enhances dopamine neuronal activity in Wistar Kyoto rats","year":2023,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Janssen Canada; Canadian Institutes of Health Research","keywords":"Locus coeruleus; Ketamine; Premovement neuronal activity; Dopamine; Phencyclidine; Antidepressant; Ventral tegmental area; Monoamine neurotransmitter; Population; Prefrontal cortex; NMDA receptor; Neuroscience; Internal medicine; Endocrinology; Chemistry; Norepinephrine; Serotonin; Pharmacology; Medicine; Hippocampus; Psychology; Central nervous system; Receptor; Dopaminergic","score_opus":0.020679671280952033,"score_gpt":0.29156707820116823,"score_spread":0.2708874069202162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388046979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954187,0.00022446348,0.00008801253,0.0010136159,0.0019093086,0.0005389885,0.000028891272,0.00012914327,0.00064885255],"genre_scores_gemma":[0.996909,0.001023727,0.00018195774,0.00090305187,0.00011068835,0.00015380328,0.000009222642,0.000025253992,0.00068326393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997887,0.00032557995,0.00029311885,0.00067136576,0.00020106182,0.0006218809],"domain_scores_gemma":[0.999426,0.0002177336,0.00010095458,0.00013673745,0.0000137675115,0.00010477207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025494437,0.00024334056,0.0003819709,0.00055696326,0.000069126996,0.00002739251,0.0003355434,0.00009000823,0.00008786418],"category_scores_gemma":[0.00015679807,0.0002436603,0.000035602465,0.0012465053,0.00040757156,0.00033972404,0.00020625792,0.00035283624,0.000017874332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053872523,0.0002657331,0.024633508,0.000092066424,0.000009644342,0.00036937336,0.00033519848,0.00016202011,0.9458213,0.000036478203,0.015950281,0.011785711],"study_design_scores_gemma":[0.003973726,0.00026511925,0.24377991,0.000020349788,0.000011105346,0.000019550262,0.00013716271,0.0072717606,0.7265824,0.00052760233,0.016964884,0.00044638236],"about_ca_topic_score_codex":0.000062062274,"about_ca_topic_score_gemma":0.00011790412,"teacher_disagreement_score":0.21923882,"about_ca_system_score_codex":0.000049267004,"about_ca_system_score_gemma":0.000047502283,"threshold_uncertainty_score":0.99361783},"labels":[],"label_agreement":null},{"id":"W4388116485","doi":"10.1016/j.jad.2023.10.153","title":"Association between serum omega-3 PUFAs levels and cognitive impairment in never medically treated first-episode patients with geriatric depression: A cross-sectional study","year":2023,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Hamd; Depression (economics); Internal medicine; Geriatric Depression Scale; Medicine; Montreal Cognitive Assessment; Anxiety; Hospital Anxiety and Depression Scale; Polyunsaturated fatty acid; Cross-sectional study; Psychiatry; Cognitive impairment; Depressive symptoms; Disease; Biology; Pathology","score_opus":0.01384335071537196,"score_gpt":0.2793666545073994,"score_spread":0.26552330379202743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388116485","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99843687,0.000021799893,0.0000549342,0.00022059825,0.00015551769,0.0009033638,0.000072194925,0.00003631518,0.000098393044],"genre_scores_gemma":[0.99968517,0.000019097373,0.0000060334382,0.00009638011,0.000057480207,0.000033071155,0.0000056360695,0.000026150794,0.00007098301],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99738514,0.00040613435,0.00047274877,0.00039139722,0.00096260686,0.00038194636],"domain_scores_gemma":[0.99749833,0.0015369618,0.0005370882,0.00007930141,0.00020145501,0.00014688159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067127997,0.00023187551,0.00035260624,0.00054167653,0.00023754562,0.00010046936,0.00016139125,0.00012445274,0.00004314919],"category_scores_gemma":[0.0015947956,0.00017698633,0.00009126283,0.0013246863,0.0000993756,0.0006393,0.00006733068,0.00040857092,0.00000924765],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004564568,0.00078776723,0.99491394,0.0000145728645,0.00013635946,0.000022831151,0.0007771208,0.00011050801,0.00003060989,0.0000010395489,0.00010121527,0.0026475608],"study_design_scores_gemma":[0.0115157105,0.0016493717,0.98555386,0.00005286587,0.00005338665,0.0000031556983,0.00053719373,0.000042038948,0.0002198289,0.00015565823,0.000019166224,0.00019777649],"about_ca_topic_score_codex":0.000111101435,"about_ca_topic_score_gemma":0.00072562613,"teacher_disagreement_score":0.011059254,"about_ca_system_score_codex":0.0002329466,"about_ca_system_score_gemma":0.00006796933,"threshold_uncertainty_score":0.72172934},"labels":[],"label_agreement":null},{"id":"W4388209437","doi":"10.1016/j.bbi.2023.10.025","title":"A randomised double-blind placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at risk Mental States: The NAYAB study","year":2023,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Stanley Medical Research Institute","keywords":"Placebo; Minocycline; Double blind; Omega 3 fatty acid; Medicine; Omega; Psychiatry; Internal medicine; Polyunsaturated fatty acid; Fatty acid; Alternative medicine; Chemistry; Philosophy; Docosahexaenoic acid; Antibiotics","score_opus":0.0736452458694906,"score_gpt":0.3594986983182069,"score_spread":0.2858534524487163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388209437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98067504,0.000031418454,0.000005933747,0.00034611596,0.00025740304,0.0182231,0.0003410405,0.00007126295,0.000048668724],"genre_scores_gemma":[0.9929245,0.00013422326,0.000018378065,0.00014695014,0.000039738006,0.00436896,0.000049908573,0.000028774573,0.0022885443],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9976153,0.0007067255,0.0005477947,0.00045006306,0.0002972868,0.00038287413],"domain_scores_gemma":[0.99637526,0.0028042088,0.00020580486,0.0004282745,0.000035187935,0.00015125365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009893237,0.00031783775,0.0006568744,0.0001694323,0.00075730466,0.000086273525,0.00027206074,0.00008012614,0.0000628203],"category_scores_gemma":[0.00082195585,0.00018948982,0.00021432457,0.0003618521,0.00022390303,0.00009853202,0.0002153735,0.00014236213,0.000009107098],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9422111,0.0022419856,0.0007710274,0.000008305977,0.000069526846,0.000007984453,0.00874908,0.000003395041,0.0397778,0.000005333679,0.00021514809,0.005939302],"study_design_scores_gemma":[0.9439916,0.008388275,0.007197494,0.000008571685,0.00024187478,0.000006856868,0.0064869714,0.00008832044,0.03283333,0.000020512469,0.00050295005,0.00023320976],"about_ca_topic_score_codex":0.00032291593,"about_ca_topic_score_gemma":0.0003958834,"teacher_disagreement_score":0.0138541395,"about_ca_system_score_codex":0.00005673877,"about_ca_system_score_gemma":0.00006860093,"threshold_uncertainty_score":0.77271706},"labels":[],"label_agreement":null},{"id":"W4388247705","doi":"10.1101/2023.10.31.564953","title":"IDO-1 inhibition improves outcome after fluid percussion injury in adult male rats","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"University of Toronto","keywords":"Kynurenine pathway; Kynurenine; Neuroprotection; Traumatic brain injury; Indoleamine 2,3-dioxygenase; Open field; Elevated plus maze; Hippocampus; Pharmacology; Neocortex; Medicine; Psychology; Internal medicine; Chemistry; Tryptophan; Anxiety; Neuroscience; Biochemistry; Psychiatry","score_opus":0.020133420242732944,"score_gpt":0.24655523764169526,"score_spread":0.22642181739896233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388247705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949459,0.000082706334,0.00005656313,0.00071197416,0.0020370635,0.0010110422,0.00039593264,0.00074079214,0.000018067221],"genre_scores_gemma":[0.996886,0.00022229587,0.00035918097,0.0013671078,0.0003084772,0.0005835184,5.606242e-7,0.00020900051,0.00006382887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99556243,0.00028782547,0.00088063965,0.0017880893,0.0006210769,0.00085993134],"domain_scores_gemma":[0.99787074,0.000103370665,0.0003252624,0.0012592633,0.00017229693,0.00026905542],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00044008967,0.000723384,0.0006226701,0.0007245396,0.0001525001,0.00031185182,0.0005849609,0.00074195577,0.00012645777],"category_scores_gemma":[0.0011602514,0.00072090334,0.00023547003,0.0010268221,0.0002089894,0.0003816801,0.0009200491,0.0011781454,0.0008317461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001191475,0.00016995074,0.0058512557,0.00042639291,0.000006761396,0.0003058098,0.00003192348,0.000010923884,0.9923693,0.00022634321,0.0004773425,0.0000048474053],"study_design_scores_gemma":[0.00059971795,0.000056145444,0.13233295,0.00049758225,0.000017565373,4.181869e-8,0.000009081067,0.00027653488,0.86484677,0.00001711873,0.0003966678,0.00094984786],"about_ca_topic_score_codex":0.000055162753,"about_ca_topic_score_gemma":0.000011638503,"teacher_disagreement_score":0.12752256,"about_ca_system_score_codex":0.0003094905,"about_ca_system_score_gemma":0.00029885586,"threshold_uncertainty_score":0.99994624},"labels":[],"label_agreement":null},{"id":"W4388297118","doi":"10.3390/ph16111557","title":"Sarcosine May Induce EGF Production or Inhibit the Decline in EGF Concentrations in Patients with Chronic Schizophrenia (Results of the PULSAR Study)","year":2023,"lang":"en","type":"article","venue":"Pharmaceuticals","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Sarcosine; Positive and Negative Syndrome Scale; Medicine; Placebo; Antipsychotic; Internal medicine; Schizophrenia (object-oriented programming); Tolerability; Endocrinology; Pharmacology; Psychosis; Adverse effect; Psychiatry; Biology; Pathology; Biochemistry","score_opus":0.06444763593048133,"score_gpt":0.3461540295451344,"score_spread":0.2817063936146531,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388297118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9886509,0.000037419017,0.0000012346173,0.008982511,0.0002406635,0.0019217797,0.00003934614,0.0000423444,0.00008381136],"genre_scores_gemma":[0.9989985,0.000049755283,0.000006362943,0.0006362305,0.000053896245,0.00008094017,0.0000060376537,0.000017464372,0.00015080564],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99785894,0.0004195496,0.00045345584,0.00042790698,0.00048011934,0.00036004785],"domain_scores_gemma":[0.9990615,0.0003457168,0.00012942907,0.00036427967,0.000047394366,0.000051669464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051074737,0.00015755482,0.0001784519,0.00012443113,0.0001278384,0.00003511326,0.00039048167,0.000038375707,0.000039776707],"category_scores_gemma":[0.0014127884,0.000082305654,0.00003148022,0.0024559011,0.0002877096,0.00016844459,0.00017625092,0.0003632953,0.000029777784],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012752059,0.0111082755,0.54502255,0.00021703735,0.00007078518,0.00005249225,0.007056168,0.0065704077,0.37139168,0.001324655,0.0043708025,0.040063098],"study_design_scores_gemma":[0.013046066,0.00034291332,0.68539655,0.000113718495,0.000022326194,0.0000019453512,0.00023669549,0.0010371538,0.29661283,0.00016241276,0.0028018183,0.00022555125],"about_ca_topic_score_codex":0.000037594848,"about_ca_topic_score_gemma":0.0006840426,"teacher_disagreement_score":0.140374,"about_ca_system_score_codex":0.00007326678,"about_ca_system_score_gemma":0.00016287065,"threshold_uncertainty_score":0.3356327},"labels":[],"label_agreement":null},{"id":"W4388447153","doi":"10.1097/st9.0000000000000012","title":"Therapeutic effects of Naohuan Dan combined with idebenone in treating mild cognitive impairment with kidney deficiency and phlegm stasis: A retrospective study","year":2023,"lang":"en","type":"article","venue":"Science of Traditional Chinese Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Internal medicine; Dementia; Observational study; Idebenone; Medical prescription; Phlegm; Mini–Mental State Examination; Physical therapy; Clinical Global Impression; Traditional Chinese medicine; Placebo; Pathology","score_opus":0.02284420640408466,"score_gpt":0.28098817767929085,"score_spread":0.25814397127520616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388447153","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976752,0.000048153648,0.000025961524,0.0005947671,0.00006413341,0.0010143245,0.000029272136,0.0000386922,0.0005095006],"genre_scores_gemma":[0.99964774,0.000014105527,0.0000394343,0.00018166532,0.000020970067,0.00006674468,0.0000071623394,0.000012758872,0.000009417203],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9975321,0.00010389212,0.00029074113,0.0005614452,0.001202712,0.00030906263],"domain_scores_gemma":[0.998684,0.0007131363,0.00018055587,0.00015694088,0.000109217595,0.0001561805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005890885,0.00021454976,0.00040098222,0.000601032,0.00018871354,0.000013492852,0.00024560094,0.000019610081,0.000010684513],"category_scores_gemma":[0.001088571,0.0001238108,0.000022044329,0.0038715503,0.002329433,0.00026956707,0.00003771442,0.00014498942,6.1686967e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002938775,0.0058752857,0.6422865,0.0006463176,0.00006572518,0.00027217102,0.038260568,0.0001189858,0.30077732,0.007373903,0.000045128756,0.0013393704],"study_design_scores_gemma":[0.0074806297,0.011649796,0.9617542,0.00069331686,0.000026866383,0.000020180278,0.0046669906,0.0004324162,0.010637897,0.0024929617,8.8704e-8,0.00014464818],"about_ca_topic_score_codex":0.00008229744,"about_ca_topic_score_gemma":0.000056516514,"teacher_disagreement_score":0.31946775,"about_ca_system_score_codex":0.000053960957,"about_ca_system_score_gemma":0.00022249928,"threshold_uncertainty_score":0.85828936},"labels":[],"label_agreement":null},{"id":"W4388500795","doi":"10.4103/1673-5374.389360","title":"Effects of Lycium barbarum polysaccharide on cytokines in adolescents with subthreshold depression: a randomized controlled study","year":2023,"lang":"en","type":"article","venue":"Neural Regeneration Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"National Natural Science Foundation of China","keywords":"Placebo; Medicine; Depression (economics); Randomized controlled trial; Internal medicine; Antidepressant; Lycium; Anxiety; Physical therapy; Psychiatry; Alternative medicine","score_opus":0.04732810827963755,"score_gpt":0.34318443612265076,"score_spread":0.2958563278430132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388500795","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99417984,0.00007785843,0.000010589121,0.00065914437,0.00015578212,0.004673709,0.0000018084503,0.00008061161,0.00016067311],"genre_scores_gemma":[0.9982199,0.000050727667,0.00000258225,0.00017121,0.000067426,0.0008735376,0.0000013722375,0.000027123713,0.00058609317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99454814,0.0024922858,0.00045099115,0.00058188185,0.0014270248,0.00049967814],"domain_scores_gemma":[0.99774903,0.0015908306,0.00010674232,0.0003300588,0.00011939752,0.000103915314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015580276,0.00019339741,0.0006991634,0.000839539,0.0001898708,0.00009154262,0.0003373988,0.00007009474,0.000015313604],"category_scores_gemma":[0.004032938,0.00012205104,0.00011493129,0.0016675026,0.0002110522,0.00014218893,0.00010930594,0.0003973122,0.000033884964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.1264614,0.0006512776,0.004516885,0.000078796475,0.000009575189,0.00017735241,0.00028667747,0.001165144,0.8657284,0.00022225447,0.00024510137,0.00045716713],"study_design_scores_gemma":[0.24614325,0.00052291044,0.012374557,0.00017740994,0.000007362907,0.0000018324845,0.00012527013,0.013083589,0.7273528,0.00008258024,0.0000028288491,0.00012558814],"about_ca_topic_score_codex":0.00007218651,"about_ca_topic_score_gemma":0.00013087537,"teacher_disagreement_score":0.13837555,"about_ca_system_score_codex":0.000032901135,"about_ca_system_score_gemma":0.000078935656,"threshold_uncertainty_score":0.4977097},"labels":[],"label_agreement":null},{"id":"W4388507716","doi":"10.1126/sciadv.adg9921","title":"Immune activation state modulates infant engram expression across development","year":2023,"lang":"en","type":"article","venue":"Science Advances","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Jacobs Foundation; Boehringer Ingelheim Fonds; Science Foundation Ireland; Lister Institute of Preventive Medicine","keywords":"Engram; Neuroscience; Dentate gyrus; Amnesia; Forgetting; Memory formation; Psychology; Offspring; Immunological memory; Immune system; Hippocampus; Biology; Cognitive psychology; Immunology; Immunity","score_opus":0.023274869633602837,"score_gpt":0.3162809657185163,"score_spread":0.2930060960849135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388507716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99818903,0.000056916364,0.0004240718,0.00017747935,0.00036532772,0.00017918501,0.00000435776,0.00030368989,0.00029996617],"genre_scores_gemma":[0.99831486,0.00006806024,0.0007476835,0.00013950391,0.000015597767,0.00003461154,0.000002160567,0.000009146779,0.0006683527],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99800706,0.00002810286,0.00021329381,0.00054160244,0.0006235009,0.00058643863],"domain_scores_gemma":[0.99940175,0.0001327473,0.0001045647,0.00023244513,0.000042921518,0.00008558034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004432616,0.00012885236,0.00010521639,0.00015398292,0.00096685486,0.000157478,0.0005530045,0.000021301374,0.00001683491],"category_scores_gemma":[0.0006947564,0.00010204718,0.00002583855,0.0018870626,0.0005861117,0.0017933262,0.00023621334,0.00009378124,0.00019330003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010310733,0.000018675279,0.00018306352,0.0000076157185,2.5722963e-7,0.0000019425313,0.0017333737,0.0010386985,0.90360826,0.00004586181,0.000011393502,0.093340576],"study_design_scores_gemma":[0.00017459258,0.00002114207,0.017111316,0.000036363697,1.5222437e-7,9.968538e-7,0.0006333873,0.00038083552,0.9732233,0.0013458768,0.006916097,0.00015591395],"about_ca_topic_score_codex":0.0000042587417,"about_ca_topic_score_gemma":0.000005639764,"teacher_disagreement_score":0.09318466,"about_ca_system_score_codex":0.000044420445,"about_ca_system_score_gemma":0.00012326398,"threshold_uncertainty_score":0.74363637},"labels":[],"label_agreement":null},{"id":"W4388561489","doi":"10.1097/md.0000000000035937","title":"Minocycline in depression not responding to first-line therapy: A systematic review and meta-analysis","year":2023,"lang":"en","type":"review","venue":"Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Global Health Research","funders":"","keywords":"Medicine; Meta-analysis; Minocycline; Placebo; Depression (economics); Internal medicine; Antidepressant; Randomized controlled trial; Major depressive disorder; Meta-regression; Psychiatry; Alternative medicine; Pathology","score_opus":0.29565634154458525,"score_gpt":0.4322277750332382,"score_spread":0.13657143348865297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388561489","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000004567644,0.9927893,0.00003512744,0.0031120435,0.000063244406,0.003795832,0.00004390055,0.00007949071,0.00007648815],"genre_scores_gemma":[0.00004120378,0.98963255,0.000018896651,0.0054538758,0.000047588608,0.00091237837,0.000024193583,0.000060217448,0.0038091026],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9955054,0.0009477321,0.0016219903,0.0009859998,0.00059121865,0.00034769002],"domain_scores_gemma":[0.9956742,0.0026399111,0.0005764717,0.00090038776,0.000026372698,0.0001826821],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019347724,0.00055832515,0.009066093,0.0026247483,0.00007965235,0.000023293995,0.00056431687,0.0001522822,0.00035671762],"category_scores_gemma":[0.0066115474,0.00029151302,0.000906803,0.007931965,0.000080780024,0.000050870945,0.00017079701,0.00034208735,0.0001095007],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012951595,0.00004214672,5.717444e-7,0.98350066,0.0070819217,0.00012526386,0.0001620357,0.0000016665588,0.000011587683,0.000029262703,0.0007170095,0.008314908],"study_design_scores_gemma":[0.00048106615,0.00013601895,0.000003834082,0.24415714,0.48612475,0.00003530902,0.000019283043,0.000017467202,0.0000136466115,0.000024118144,0.2684359,0.0005514621],"about_ca_topic_score_codex":0.000027317825,"about_ca_topic_score_gemma":0.000079183905,"teacher_disagreement_score":0.7393435,"about_ca_system_score_codex":0.000038201717,"about_ca_system_score_gemma":0.000031783937,"threshold_uncertainty_score":0.9999537},"labels":[],"label_agreement":null},{"id":"W4388627771","doi":"10.1139/cjpp-2023-0107","title":"TLR/mTOR inflammatory signaling pathway: novel insight for the treatment of schizophrenia","year":2023,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"PI3K/AKT/mTOR pathway; Signal transduction; Cytokine; Pharmacology; Inflammation; Tumor necrosis factor alpha; Synaptic plasticity; Medicine; Biology; Cancer research; Receptor; Cell biology; Immunology; Internal medicine","score_opus":0.08535429495006223,"score_gpt":0.3280728300500063,"score_spread":0.24271853509994407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388627771","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00523365,0.99152195,0.000009834166,0.00014121675,0.0021219125,0.0006695438,0.00028074,0.0000071970308,0.000013949871],"genre_scores_gemma":[0.0029262092,0.99557984,0.000018589899,0.00043453262,0.00081229454,0.000063768595,0.000006614142,0.000039837647,0.000118297656],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99842906,0.0002551226,0.00062333315,0.00025824134,0.000059645256,0.00037458242],"domain_scores_gemma":[0.9966157,0.0022096287,0.0007109508,0.0001229633,0.000066469736,0.00027428212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016451417,0.00029242027,0.0010987816,0.00036749642,0.00025481082,0.000011162279,0.00039947947,0.00026508022,0.00023623824],"category_scores_gemma":[0.00009779038,0.00018278662,0.00043768613,0.00021919314,0.0005386321,0.00005878852,0.000015313217,0.00031067032,0.000008026326],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045998133,0.00026199545,0.0000025710965,0.01068105,0.0016861595,0.0002662882,0.0016039128,0.00012039375,0.46332315,0.0024681913,0.0067317826,0.51239455],"study_design_scores_gemma":[0.0011730106,0.0005593279,0.0000061320957,0.00032834,0.00039437672,0.000085447464,0.000019039193,0.000010312647,0.017634094,0.0002081088,0.9794159,0.0001659375],"about_ca_topic_score_codex":0.0000514308,"about_ca_topic_score_gemma":0.00022340582,"teacher_disagreement_score":0.9726841,"about_ca_system_score_codex":0.00008156236,"about_ca_system_score_gemma":0.00206417,"threshold_uncertainty_score":0.7453822},"labels":[],"label_agreement":null},{"id":"W4388638077","doi":"10.3390/jcm12227049","title":"The Effect of Antidepressant Treatment on Neurocognitive Functions, Redox and Inflammatory Parameters in the Context of COVID-19","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Antidepressant; Internal medicine; Glutathione peroxidase; Depression (economics); Context (archaeology); Major depressive disorder; Oxidative stress; Glutathione reductase; Montreal Cognitive Assessment; Beck Depression Inventory; Superoxide dismutase; Gastroenterology; Psychiatry; Dementia; Disease","score_opus":0.08344859476575481,"score_gpt":0.4048364904109236,"score_spread":0.3213878956451688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388638077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898624,0.0001972275,0.0000065402346,0.008929105,0.0004057292,0.0003016475,0.0000045866686,0.0000051297106,0.00028767533],"genre_scores_gemma":[0.99581575,0.0023332513,0.0000014281921,0.0017284757,0.00008583395,0.0000057426955,2.9081366e-7,0.000005356273,0.00002388696],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9970188,0.0013648912,0.0009719077,0.00013341065,0.0003904302,0.00012055386],"domain_scores_gemma":[0.9631283,0.03593611,0.0006457479,0.00015665549,0.000032832344,0.00010034791],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0029672799,0.00009779916,0.00045697426,0.00012188029,0.000064336775,0.0000058017395,0.000190068,0.000045959772,0.0000051499273],"category_scores_gemma":[0.031784885,0.000038913386,0.0001319807,0.0002735334,0.0008531998,0.000038096212,0.000021027883,0.00029054657,0.0000024928813],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.034736395,0.0014561259,0.35663924,0.0005317905,0.00042455673,0.0021583545,0.0087281065,0.00061876705,0.036139406,0.0015741237,0.02769529,0.5292978],"study_design_scores_gemma":[0.03895102,0.06540966,0.82084006,0.0010313543,0.0002957411,0.00022763155,0.011819249,0.00043855704,0.03897613,0.0015489213,0.020229358,0.0002322945],"about_ca_topic_score_codex":0.000014832344,"about_ca_topic_score_gemma":0.000012616772,"teacher_disagreement_score":0.52906555,"about_ca_system_score_codex":0.000010672056,"about_ca_system_score_gemma":0.00007008984,"threshold_uncertainty_score":0.9763708},"labels":[],"label_agreement":null},{"id":"W4388687371","doi":"10.1186/s13229-023-00569-y","title":"Hyperthermia elevates brain temperature and improves behavioural signs in animal models of autism spectrum disorder","year":2023,"lang":"en","type":"article","venue":"Molecular Autism","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"Simons Foundation Autism Research Initiative; Simons Foundation","keywords":"Autism spectrum disorder; Autism; Hyperthermia; Neuropsychology; Analysis of variance; Post-hoc analysis; Neurology; Post hoc; Neurodevelopmental disorder; Medicine; Psychology; Neuroscience; Clinical psychology; Developmental psychology; Internal medicine; Cognition","score_opus":0.01583199322345307,"score_gpt":0.2389919641531359,"score_spread":0.22315997092968282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388687371","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911922,0.00034391935,0.000053903816,0.007587906,0.00007786963,0.00032636712,0.000033390173,0.00014152404,0.00024287742],"genre_scores_gemma":[0.99884504,0.00005890899,0.000056667828,0.000609548,0.0000026273785,0.000024357025,0.000009814739,0.000046374924,0.000346652],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833995,0.00012444514,0.0002647962,0.0005295626,0.00026722666,0.00047403065],"domain_scores_gemma":[0.9994807,0.00009628761,0.00006681702,0.00026716737,0.0000045111856,0.000084509215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001213789,0.00023635011,0.00026176582,0.00024701457,0.000083021616,0.00005466148,0.00024821586,0.0001574351,0.00002478987],"category_scores_gemma":[0.00009150456,0.00022469608,0.00008758943,0.0007078836,0.00019732553,0.00019899374,0.0001496972,0.00025636575,0.000013324457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023300074,0.00006738504,0.00031682785,0.000021757265,0.000004278283,0.00015908742,0.00050327025,0.000145813,0.97647077,0.021530408,0.00007466814,0.0006824385],"study_design_scores_gemma":[0.002583429,0.000677282,0.3282436,0.00009185111,0.000016988375,0.000060373983,0.00028480234,0.015004366,0.585505,0.06651105,0.00018882622,0.0008324345],"about_ca_topic_score_codex":0.00015257172,"about_ca_topic_score_gemma":0.0000654475,"teacher_disagreement_score":0.3909658,"about_ca_system_score_codex":0.000017700895,"about_ca_system_score_gemma":0.000043739103,"threshold_uncertainty_score":0.91628397},"labels":[],"label_agreement":null},{"id":"W4388756448","doi":"10.1101/2023.11.15.567229","title":"LPS-Induced Inflammation Reduces GABAergic Interneuron markers and Brain-derived Neurotrophic Factor in Mouse Prefrontal Cortex and Hippocampus","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Endocrinology; Internal medicine; Cholecystokinin; Parvalbumin; Prefrontal cortex; Somatostatin; GABAergic; Hippocampus; Neuropeptide Y receptor; Brain-derived neurotrophic factor; Interneuron; Neurotrophic factors; Neuropeptide; Vasoactive intestinal peptide; Inflammation; Biology; Medicine; Neuroscience; Receptor","score_opus":0.025233470938548618,"score_gpt":0.2351304526452912,"score_spread":0.2098969817067426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388756448","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963151,0.00014035957,0.00001716845,0.0005887222,0.00095905544,0.0012630317,0.00013779762,0.0005728951,0.000005851923],"genre_scores_gemma":[0.99852407,0.000509386,0.000110828485,0.00034373757,0.0001422399,0.00016860478,4.3471732e-7,0.0001841995,0.00001651699],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960202,0.0004442866,0.00065364037,0.0017853801,0.00043005677,0.0006664575],"domain_scores_gemma":[0.9981348,0.00030826693,0.0004499529,0.0007282239,0.000075319746,0.00030343633],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002693249,0.00070477504,0.00059361546,0.000601785,0.00015369833,0.00043042027,0.00053722394,0.00047173564,0.000017059217],"category_scores_gemma":[0.0013297548,0.000778451,0.00009652163,0.00046147697,0.00027996802,0.00037709787,0.00088731333,0.0010155969,0.000031405398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011933244,0.00005404031,0.0020716928,0.00027624605,0.000018464569,0.00014025359,0.00007044021,0.000012794258,0.9971385,0.000045080564,0.000026408345,0.000026736921],"study_design_scores_gemma":[0.00081238395,0.00010883086,0.41667935,0.00022047307,0.000011151123,1.0962679e-7,0.000011052576,0.0007258114,0.5807942,0.0000091216825,0.000041634135,0.0005858755],"about_ca_topic_score_codex":0.00007853138,"about_ca_topic_score_gemma":0.000028773908,"teacher_disagreement_score":0.41634429,"about_ca_system_score_codex":0.00016044223,"about_ca_system_score_gemma":0.00024264214,"threshold_uncertainty_score":0.99946666},"labels":[],"label_agreement":null},{"id":"W4388765999","doi":"10.1038/s41398-023-02646-5","title":"eIF4E phosphorylation mediated LPS induced depressive-like behaviors via ameliorated neuroinflammation and dendritic loss","year":2023,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Sanming Project of Medicine in Shenzhen; Shenzhen-Hong Kong Institute of Brain Science; National Natural Science Foundation of China","keywords":"Tropomyosin receptor kinase B; Neuroinflammation; Synaptic plasticity; Dendritic spine; Neuroscience; Brain-derived neurotrophic factor; Signal transduction; Neurotrophin; Neurotrophic factors; Medicine; Cell biology; Internal medicine; Receptor; Psychology; Inflammation; Biology","score_opus":0.022900994297860047,"score_gpt":0.26918617008307405,"score_spread":0.246285175785214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388765999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99503386,0.000083897176,0.00046453622,0.0023619027,0.0008779172,0.0003986746,0.000048414957,0.00042640796,0.00030441384],"genre_scores_gemma":[0.99900717,0.00004550522,0.00015029186,0.00039949027,0.000089431494,0.000032570577,0.0001714005,0.000039922044,0.0000642112],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99818206,0.00015555263,0.00036995154,0.0005108393,0.00047218666,0.0003094352],"domain_scores_gemma":[0.9992567,0.0002706681,0.000115798975,0.00018166326,0.000049187493,0.00012601375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013228875,0.00021666063,0.00015715937,0.00028333295,0.00032678194,0.00006868649,0.00015958952,0.00014784856,0.0001189203],"category_scores_gemma":[0.000087102926,0.0002310305,0.00006703738,0.0011162324,0.00011584615,0.00040385843,0.000017124912,0.00026779776,0.00024860795],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021904675,0.00023829888,0.051878314,0.000070973394,0.000017682118,0.000034599227,0.000965405,0.0010725379,0.9359036,0.0039663734,0.00059774856,0.0050354013],"study_design_scores_gemma":[0.0032972903,0.00013149384,0.931427,0.000057929705,0.000046647605,0.0000597187,0.0001360906,0.017255034,0.031677205,0.014932391,0.0003309909,0.0006481784],"about_ca_topic_score_codex":0.000015112277,"about_ca_topic_score_gemma":0.000048345762,"teacher_disagreement_score":0.9042264,"about_ca_system_score_codex":0.000011029768,"about_ca_system_score_gemma":0.00009528322,"threshold_uncertainty_score":0.942115},"labels":[],"label_agreement":null},{"id":"W4388835527","doi":"10.1016/j.jpsychires.2023.11.031","title":"Proteomic profiling in the progression of psychosis: Analysis of clinical high-risk, first episode psychosis, and healthy controls","year":2023,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Vancouver Coastal Health; Lions Gate Hospital; University of British Columbia Hospital","funders":"National Research Foundation of Korea; Korea Health Industry Development Institute; Ministry of Health and Welfare; Ministry of Science, ICT and Future Planning","keywords":"Psychosis; Internal medicine; Schizophrenia (object-oriented programming); Disease; Pathogenesis; Pathological; Medicine; Psychology; Oncology; Psychiatry","score_opus":0.1091817604312074,"score_gpt":0.47365824996041334,"score_spread":0.3644764895292059,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388835527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894062,0.0011520197,0.00004825548,0.007972786,0.00031309467,0.0009570376,0.000018639987,0.000008578591,0.0001233814],"genre_scores_gemma":[0.990276,0.008414863,0.00095333206,0.000108762535,0.0001718637,0.000049771097,9.635257e-7,0.00001500163,0.000009443718],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99293005,0.0026493608,0.0019006727,0.00039528956,0.0016387197,0.00048590518],"domain_scores_gemma":[0.9949821,0.0028767474,0.0013013023,0.00043605687,0.00025230614,0.00015144281],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.013628793,0.0001419001,0.00075846334,0.0023822,0.00021304526,0.000051881765,0.00086651376,0.00014759506,0.000015245342],"category_scores_gemma":[0.0034778886,0.000087137145,0.00037044357,0.007992701,0.00037756003,0.00013082598,0.00007604411,0.0013168086,0.000004535079],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002311132,0.000991348,0.9748238,0.00021508371,0.00015749087,0.000012066268,0.00047091758,0.0001957364,0.0012580006,0.0006293157,0.0042456617,0.014689485],"study_design_scores_gemma":[0.0043248804,0.0027853893,0.9854528,0.00015445432,0.00014757457,0.0000070107235,0.00057428033,0.0023452211,0.0012251945,0.002400462,0.00046333077,0.00011944955],"about_ca_topic_score_codex":0.00022795863,"about_ca_topic_score_gemma":0.00018081485,"teacher_disagreement_score":0.014570035,"about_ca_system_score_codex":0.000017200287,"about_ca_system_score_gemma":0.0001307741,"threshold_uncertainty_score":0.57209516},"labels":[],"label_agreement":null},{"id":"W4389009220","doi":"10.1016/j.bbi.2023.11.025","title":"Behavioral as well as hippocampal transcriptomic and microglial responses differ across sexes in adult mouse offspring exposed to a dual genetic and environmental challenge","year":2023,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of British Columbia; Université Laval; University of Victoria","funders":"","keywords":"Schizophrenia (object-oriented programming); Offspring; Microglia; Hippocampal formation; DISC1; Hippocampus; Neuroscience; Transcriptome; Psychology; Biology; Psychiatry; Pregnancy; Gene; Immunology; Genetics; Inflammation; Gene expression","score_opus":0.03225442957425325,"score_gpt":0.2909972527851324,"score_spread":0.25874282321087916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389009220","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99845266,0.00014012879,0.0000011060177,0.00028738636,0.00009307062,0.0006321282,0.0002824217,0.00009588324,0.000015203716],"genre_scores_gemma":[0.9980161,0.00040682146,0.000024653313,0.0004790729,0.000019558036,0.000096955344,0.000014318114,0.000043431937,0.00089904625],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980439,0.00031658603,0.00029184954,0.0005769303,0.00021822746,0.00055251305],"domain_scores_gemma":[0.999222,0.00022519316,0.000042632004,0.0002823242,0.0000052533155,0.00022262432],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019500818,0.00030460051,0.00027645222,0.0001849886,0.0003736024,0.0001391877,0.0001810842,0.00014605894,0.000056541445],"category_scores_gemma":[0.00011232231,0.00031866427,0.000053847234,0.00016350334,0.00043419658,0.00017769917,0.00027639634,0.00033424265,0.000042750045],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043706945,0.00038357475,0.018993989,0.00001720519,0.0000019192432,0.00015497199,0.010340016,3.7127262e-7,0.95917934,0.000007487635,0.000016790678,0.010467275],"study_design_scores_gemma":[0.0030845806,0.0007389972,0.6023303,0.00002693639,0.000017298635,0.00012129868,0.009136891,0.000022808,0.38378987,0.00003323064,0.00022898414,0.0004687593],"about_ca_topic_score_codex":0.00040475818,"about_ca_topic_score_gemma":0.00036207488,"teacher_disagreement_score":0.58333635,"about_ca_system_score_codex":0.00003537393,"about_ca_system_score_gemma":0.00002173154,"threshold_uncertainty_score":0.99992657},"labels":[],"label_agreement":null},{"id":"W4389024222","doi":"10.1096/fasebj.31.1_supplement.1015.18","title":"Comorbidity Between Metabolic Syndrome and Depression Exacerbates Oxidative Stress and Inflammation in the Brain","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Institut National de la Santé et de la Recherche Médicale","keywords":"Oxidative stress; Internal medicine; Inflammation; Endocrinology; Medicine; Metabolic syndrome","score_opus":0.039203405042638834,"score_gpt":0.2889667659829398,"score_spread":0.24976336094030097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389024222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960465,0.00024244882,0.000044290045,0.0031739352,0.00006286476,0.00014772612,0.000012601235,0.0000070302044,0.00026263576],"genre_scores_gemma":[0.999387,0.000294372,0.000014026461,0.00017040705,0.00009305898,0.0000033524261,7.3308235e-7,0.0000056180324,0.000031398544],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989258,0.00043600975,0.00013971451,0.00013390428,0.00020437488,0.00016018559],"domain_scores_gemma":[0.99892217,0.0005831777,0.00019942106,0.00023269917,0.000012712647,0.00004979692],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067837455,0.00009457941,0.00012389761,0.00004947455,0.0009489264,0.000428668,0.0004414857,0.000034672816,0.000013081631],"category_scores_gemma":[0.0008522685,0.000048791797,0.000022098231,0.00005268545,0.00029705872,0.00043082467,0.00012171852,0.00032763422,0.0000033295535],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078774596,0.00006685761,0.3424929,0.00003179959,0.000028230772,0.00017406567,0.011247936,0.000032790707,0.582324,0.0014027606,0.00032045855,0.061799396],"study_design_scores_gemma":[0.000517253,0.000023799146,0.77023333,0.000043265278,0.000008787396,0.00018196934,0.0006242511,0.000079263846,0.22503826,0.0030785892,0.000103209284,0.00006799539],"about_ca_topic_score_codex":0.00003538625,"about_ca_topic_score_gemma":0.000041236686,"teacher_disagreement_score":0.42774042,"about_ca_system_score_codex":0.000005619199,"about_ca_system_score_gemma":0.0000142866975,"threshold_uncertainty_score":0.729847},"labels":[],"label_agreement":null},{"id":"W4389042026","doi":"10.1073/pnas.2305778120","title":"Social stress induces autoimmune responses against the brain","year":2023,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; Wellcome Trust; National Science Foundation; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Autoimmunity; Immunology; Antibody; Anhedonia; Immune system; Social defeat; Social stress; Chronic stress; Immunoglobulin G; Medicine; Internal medicine; Psychiatry; Dopamine","score_opus":0.09072921058277351,"score_gpt":0.34775932584422364,"score_spread":0.25703011526145014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389042026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94396394,0.000026664438,4.284973e-8,0.048365597,0.00002870327,0.0001454128,0.000024163379,0.000043469186,0.007402026],"genre_scores_gemma":[0.99712145,0.00002449741,0.000017512657,0.0019170126,0.00006935463,0.000011412278,7.12583e-8,0.0000044763433,0.0008342255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979285,0.000029661127,0.00024945033,0.00025269517,0.0013324658,0.00020719826],"domain_scores_gemma":[0.99874675,0.0008297777,0.00031558526,0.000008581741,0.00008186411,0.000017412605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014989141,0.00008923553,0.00011031519,0.00018980708,0.0007452577,0.00005741639,0.0015348466,0.000066168606,0.000008724557],"category_scores_gemma":[0.003991982,0.00004959146,0.00008526724,0.0022030156,0.0019726283,0.0003566594,0.00026947862,0.00019578218,0.0000070259903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016222912,0.000023205226,0.00033695725,0.000017986426,0.0000028956583,9.181359e-9,0.00083059224,0.000028760895,0.93073094,0.06193508,0.005172293,0.0009050775],"study_design_scores_gemma":[0.00014422573,0.000019324994,0.15971386,0.00003641441,0.0000019190627,0.0000015931183,0.0010473962,0.00034459285,0.79749256,0.04012554,0.0009952993,0.000077299905],"about_ca_topic_score_codex":0.0000022609006,"about_ca_topic_score_gemma":5.2555947e-8,"teacher_disagreement_score":0.1593769,"about_ca_system_score_codex":0.000014854346,"about_ca_system_score_gemma":0.000049556846,"threshold_uncertainty_score":0.7268231},"labels":[],"label_agreement":null},{"id":"W4389381445","doi":"10.21203/rs.3.rs-3670473/v1","title":"Nrf2 activation rescues stress-induced depression-like behaviour and inflammatory responses in male but not female rats","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Depression (economics); Stress (linguistics); Endocrinology; Inflammation; Psychology; Internal medicine; Medicine; Economics; Keynesian economics; Philosophy","score_opus":0.1506396386111924,"score_gpt":0.40313278044310574,"score_spread":0.25249314183191335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389381445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99642897,0.00011573876,0.000004112661,0.0006673469,0.0002805527,0.0015979091,0.00025237282,0.00022510832,0.00042788178],"genre_scores_gemma":[0.9944514,0.00057690527,0.00003560817,0.000071901704,0.00015027757,0.00054008455,0.000053230902,0.000095023024,0.0040255715],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99337846,0.002001977,0.000500891,0.0015094315,0.0016776898,0.0009315359],"domain_scores_gemma":[0.99592775,0.0024299454,0.00015662245,0.0010228121,0.000205836,0.00025702073],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0016188158,0.0003796433,0.00040123245,0.0013952653,0.00042718498,0.0004050932,0.0007944471,0.0005816513,0.00009911406],"category_scores_gemma":[0.00593514,0.00037180973,0.00009999093,0.000705829,0.00032944695,0.00031650966,0.0022993514,0.0023484388,0.00011221682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013913893,0.00033002617,0.18810701,0.0013522913,0.000011842434,0.00074344897,0.002055002,0.00017169079,0.80126715,0.00016799555,0.0012252048,0.0031769723],"study_design_scores_gemma":[0.00050632306,0.000079959544,0.4940671,0.0013356621,0.000002442118,0.000005053457,0.0016253414,0.00014489956,0.5014226,0.0004175794,0.00007768314,0.00031533424],"about_ca_topic_score_codex":0.00081708515,"about_ca_topic_score_gemma":0.0006429789,"teacher_disagreement_score":0.3059601,"about_ca_system_score_codex":0.00022026394,"about_ca_system_score_gemma":0.00062899734,"threshold_uncertainty_score":0.9999532},"labels":[],"label_agreement":null},{"id":"W4389762523","doi":"10.1038/s41398-023-02696-9","title":"Metabolic features of treatment-refractory major depressive disorder with suicidal ideation","year":2023,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Children's Hospital of Pittsburgh; Clinical and Translational Science Institute, University of Pittsburgh; National Center for Advancing Translational Sciences; National Center for Research Resources; University of Pittsburgh; Medical Center, University of Pittsburgh; National Institutes of Health; Brain and Behavior Research Foundation; Wright Family Foundation; University of California, San Diego; National Alliance for Research on Schizophrenia and Depression; American Foundation for Suicide Prevention","keywords":"Suicidal ideation; Internal medicine; Medicine; Metabolomics; Cohort; Bioinformatics; Endocrinology; Oncology; Biology; Poison control","score_opus":0.01781166136296695,"score_gpt":0.27619322396686957,"score_spread":0.2583815626039026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389762523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903221,0.00095933105,0.0003952365,0.0021992635,0.00030533,0.00036495298,0.00015861941,0.00018151493,0.005113648],"genre_scores_gemma":[0.9984855,0.00007312516,0.0004418425,0.00018730263,0.00009560913,0.000034866574,0.00006802065,0.000027087097,0.0005866158],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.9989155,0.00006009809,0.0001932357,0.00031902338,0.00030162514,0.00021053226],"domain_scores_gemma":[0.999492,0.00015939746,0.00009331622,0.00017475565,0.00002658741,0.000053961434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003686305,0.00017103874,0.00017184764,0.0001854328,0.00013254718,0.000017528266,0.0001357481,0.0000650945,0.00014288559],"category_scores_gemma":[0.000018187344,0.00012978693,0.000102295984,0.0005832692,0.00011480628,0.00019209822,0.00000549666,0.00008518995,0.000052094103],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022445158,0.0018613009,0.30380234,0.00022346192,0.00036864265,0.000014502428,0.003391295,0.013084968,0.23100427,0.39964926,0.003156995,0.041198473],"study_design_scores_gemma":[0.004332138,0.00028354992,0.9599917,0.000018160277,0.00006361323,0.000010181758,0.00017629865,0.00021291632,0.020181617,0.010500144,0.0039303526,0.00029936215],"about_ca_topic_score_codex":0.0000882935,"about_ca_topic_score_gemma":0.0005005913,"teacher_disagreement_score":0.6561893,"about_ca_system_score_codex":0.000007366178,"about_ca_system_score_gemma":0.00015380193,"threshold_uncertainty_score":0.52925575},"labels":[],"label_agreement":null},{"id":"W4390064827","doi":"10.1016/j.redox.2023.103005","title":"Enhancing HIF-1α–P2X2 signaling in dorsal raphe serotonergic neurons promotes psychological resilience","year":2023,"lang":"en","type":"article","venue":"Redox Biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canada First Research Excellence Fund; National Natural Science Foundation of China; Fondation Brain Canada","keywords":"Serotonergic; Dorsal raphe nucleus; Antidepressant; Hypoxia (environmental); Neuroscience; Psychology; Blockade; Medicine; Serotonin; Internal medicine; Receptor; Pharmacology; Endocrinology; Hippocampus; Chemistry","score_opus":0.034994322130412266,"score_gpt":0.3223106512372483,"score_spread":0.287316329106836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390064827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963899,0.00007804971,0.00008763972,0.001113957,0.0003882779,0.00036129807,0.000008002878,0.00034720832,0.0012256381],"genre_scores_gemma":[0.998494,0.0001044762,0.00013861546,0.0008917549,0.000059541773,0.00005867212,0.0000059459912,0.000018858089,0.00022813461],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974969,0.00045321262,0.00035155323,0.00085968105,0.0001296142,0.00070901326],"domain_scores_gemma":[0.998864,0.0006447319,0.00008624082,0.00031485895,0.0000132184,0.00007697694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035796658,0.00020014895,0.00025995699,0.00027731198,0.0001569762,0.000028519227,0.0004909425,0.00020473002,0.00013503332],"category_scores_gemma":[0.0011966488,0.00016486584,0.000082317056,0.0014877041,0.00030347033,0.00008783677,0.00016060182,0.0003573487,0.00035368916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043365224,0.00007776366,0.0013340145,0.0000096308395,0.0000012124748,0.00009373344,0.00019420752,0.0000898596,0.99354213,0.002346642,0.00011203746,0.0021553796],"study_design_scores_gemma":[0.0009077766,0.00056067074,0.019867443,0.00004524825,0.0000027065016,0.00006337878,0.00022203592,0.0007231425,0.96500206,0.01045942,0.001739022,0.00040708156],"about_ca_topic_score_codex":0.000021301843,"about_ca_topic_score_gemma":0.000029060746,"teacher_disagreement_score":0.028540079,"about_ca_system_score_codex":0.000020119063,"about_ca_system_score_gemma":0.000029969138,"threshold_uncertainty_score":0.6723034},"labels":[],"label_agreement":null},{"id":"W4390111310","doi":"10.3389/fimmu.2023.1264012","title":"Inhibition of ERO1a and IDO1 improves dendritic cell infiltration into pancreatic ductal adenocarcinoma","year":2023,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"Robert Lundbergs Minnesstiftelse; Radiumhemmets Forskningsfonder; Cancerfonden; Karolinska Institutet; Nanyang Technological University","keywords":"Infiltration (HVAC); Downregulation and upregulation; Myeloid; Cancer research; Tumor microenvironment; Monocyte; Immune system; Chemistry; Cell biology; Biology; Immunology","score_opus":0.009711870356285303,"score_gpt":0.2186425134555546,"score_spread":0.20893064309926931,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390111310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996677,0.0014011889,0.00034804308,0.00017663358,0.00065675855,0.00020241187,0.000004626761,0.000063947205,0.0004693946],"genre_scores_gemma":[0.9985066,0.0005450618,0.00062170805,0.00009201557,0.000017578264,0.000026617683,0.000010841322,0.000013749665,0.00016581223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989886,0.0001313596,0.00025167136,0.0002898606,0.00009062737,0.0002478706],"domain_scores_gemma":[0.9996204,0.00009758007,0.00008212788,0.00016257961,0.000013979233,0.00002335814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000089738074,0.0001134602,0.00020664826,0.00038118826,0.00006403115,0.000015396277,0.00010921463,0.00011621482,0.000009182813],"category_scores_gemma":[0.00024360369,0.00012065844,0.00003138654,0.00049184496,0.00037815986,0.00018425251,0.00007071962,0.00014822335,0.000013049783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005985999,0.000041441814,0.0152866775,0.000063428684,0.0000053783065,0.000021386888,0.0012795201,0.0000040898294,0.98036754,0.0006051228,0.0006082645,0.0016573082],"study_design_scores_gemma":[0.0018024613,0.00040171872,0.25972,0.000044571407,0.000013684892,0.000032793996,0.0043966207,0.0006950678,0.71841365,0.0140571,0.00017002664,0.00025228475],"about_ca_topic_score_codex":0.00005464117,"about_ca_topic_score_gemma":0.000014713324,"teacher_disagreement_score":0.26195386,"about_ca_system_score_codex":0.00003233829,"about_ca_system_score_gemma":0.000041313502,"threshold_uncertainty_score":0.49203083},"labels":[],"label_agreement":null},{"id":"W4390111802","doi":"10.1192/bjp.2023.148","title":"Features of immunometabolic depression as predictors of antidepressant treatment outcomes: pooled analysis of four clinical trials","year":2023,"lang":"en","type":"article","venue":"The British Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta; Dalhousie University","funders":"National Institute of Mental Health; Sixth Framework Programme; Otsuka Pharmaceutical; Otsuka Canada Pharmaceutical; Novo Nordisk; ZonMw; Laureate Institute for Brain Research, University of Tulsa; European Commission; ACADIA Pharmaceuticals; University of Oxford; Janssen Scientific Affairs; Neurocrine Biosciences; Brain and Behavior Research Foundation; Takeda Pharmaceuticals U.S.A.; Medical Research Council; Biogen; American Foundation for Suicide Prevention; H. Lundbeck A/S; Patient-Centered Outcomes Research Institute; Sage Therapeutics; GlaxoSmithKline","keywords":"Internal medicine; Medicine; Meta-analysis; Body mass index; Antidepressant; Depression (economics); Atypical depression; Clinical trial; Pooled analysis","score_opus":0.0643224984415734,"score_gpt":0.37829219667097835,"score_spread":0.31396969822940496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390111802","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926291,0.004656856,0.000025355932,0.0004480737,0.0014612436,0.00023536748,0.00016217203,0.00001651516,0.00036531224],"genre_scores_gemma":[0.9926404,0.0067588957,0.00012920449,0.00010635104,0.0001455278,0.000002848599,0.000003220433,0.000018881397,0.00019467842],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99500364,0.0015500464,0.0023114937,0.00023248572,0.0006750888,0.0002272545],"domain_scores_gemma":[0.9949277,0.0018144147,0.0026281157,0.00040920125,0.00011947832,0.00010106075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030552046,0.00017419214,0.0016316696,0.000477654,0.00013045654,0.000047171183,0.00070311996,0.00011509182,0.00010234461],"category_scores_gemma":[0.0033726816,0.0001144329,0.0018286998,0.0014732743,0.00028363508,0.000121950696,0.00007883297,0.0002691094,0.000002422518],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018821997,0.002959502,0.8346388,0.0001165,0.009221855,0.00009991453,0.0005950034,0.0012058318,0.04347684,0.00041717218,0.0050020367,0.1003844],"study_design_scores_gemma":[0.002852608,0.00042644294,0.9861977,0.00021890466,0.0023004615,0.00010475945,0.00043973693,0.000028375225,0.0063680275,0.0008737067,0.00009064533,0.000098636054],"about_ca_topic_score_codex":0.00025361366,"about_ca_topic_score_gemma":0.00009810215,"teacher_disagreement_score":0.15155895,"about_ca_system_score_codex":0.000010079555,"about_ca_system_score_gemma":0.00020482448,"threshold_uncertainty_score":0.4666438},"labels":[],"label_agreement":null},{"id":"W4390193726","doi":"10.1002/alz.080138","title":"Neuroinflammation Exacerbates Irritability and Agitation in Alzheimer’s Disease","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Irritability; Apathy; Precuneus; Disinhibition; Psychology; Posterior cingulate; Internal medicine; Depression (economics); Dementia; Clinical psychology; Anxiety; Psychiatry; Neuroscience; Disease; Medicine; Cognition","score_opus":0.046790419604892955,"score_gpt":0.28530894797389317,"score_spread":0.23851852836900023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390193726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98932934,0.00656136,0.0000113856895,0.002542913,0.00021258187,0.00048187005,0.0000121823705,0.0002412275,0.0006071712],"genre_scores_gemma":[0.99926156,0.000121369994,0.00006447127,0.00044424683,0.000023816527,0.000036275927,0.000022850094,0.000019969086,0.000005466946],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9985833,0.00016083758,0.00025617535,0.0004771733,0.00022556906,0.00029689886],"domain_scores_gemma":[0.99934304,0.00021612617,0.00006640759,0.00023238856,0.000026481639,0.00011557996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021448766,0.00014825648,0.000110512534,0.0001657438,0.000115929266,0.000081801874,0.00013684333,0.000036126366,0.000088198365],"category_scores_gemma":[0.0003622602,0.00015384515,0.00003979062,0.000528458,0.00011409268,0.0004279219,0.00009736624,0.00008749974,0.00024468402],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004410959,0.0007495889,0.1326802,0.00006685326,0.0010007346,0.00027763168,0.0052976557,0.0010093153,0.32527557,0.019431146,0.012739577,0.5010306],"study_design_scores_gemma":[0.0010846633,0.000047283225,0.89226794,0.00001907614,0.0009881883,0.000002024978,0.0002748898,0.007870757,0.08244779,0.011670394,0.0028742338,0.00045272955],"about_ca_topic_score_codex":0.00002980741,"about_ca_topic_score_gemma":0.00006475501,"teacher_disagreement_score":0.75958776,"about_ca_system_score_codex":0.0000025280779,"about_ca_system_score_gemma":0.000025551552,"threshold_uncertainty_score":0.6273623},"labels":[],"label_agreement":null},{"id":"W4390198983","doi":"10.1002/alz.080037","title":"Association between plasma inflammatory biomarkers and [<sup>18</sup>F]FDG‐PET signal in a transgenic amyloid rat model","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Neuroinflammation; Positron emission tomography; Pathogenesis; Genetically modified mouse; Pathology; Medicine; Internal medicine; Endocrinology; Chemistry; Inflammation; Transgene; Nuclear medicine; Biochemistry; Gene","score_opus":0.036057506499706134,"score_gpt":0.2600830004425281,"score_spread":0.22402549394282195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390198983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99693185,0.0008786521,0.00007126241,0.00057382166,0.00008707742,0.00044992045,0.000048585855,0.00020860342,0.00075024186],"genre_scores_gemma":[0.99919266,0.00014867171,0.0001356459,0.00028558084,0.000043410815,0.000061791805,0.000028624578,0.00004005337,0.00006357832],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99777216,0.00019778205,0.00041353982,0.0005731213,0.00044484684,0.00059855654],"domain_scores_gemma":[0.9992085,0.00031633922,0.00012467497,0.00020073004,0.00001993036,0.00012983025],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045184515,0.00024963397,0.00024241612,0.00032068044,0.00017265268,0.00009380287,0.00027571857,0.00012188298,0.00015670106],"category_scores_gemma":[0.00007539962,0.00026889498,0.000099734556,0.00067784,0.000095305906,0.0003703452,0.00009538784,0.0002099718,0.00018131312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004956671,0.00042417765,0.23122483,0.000103643855,0.010153672,0.00020885047,0.007663214,0.018761072,0.6082155,0.0010155146,0.048959527,0.07277432],"study_design_scores_gemma":[0.009883066,0.00026229315,0.08049129,0.000096167925,0.005481531,0.000011447492,0.00086585275,0.34752548,0.54039866,0.0043386593,0.008476414,0.0021691108],"about_ca_topic_score_codex":0.000021569367,"about_ca_topic_score_gemma":0.00006136648,"teacher_disagreement_score":0.3287644,"about_ca_system_score_codex":0.00002029323,"about_ca_system_score_gemma":0.0000764778,"threshold_uncertainty_score":0.99997634},"labels":[],"label_agreement":null},{"id":"W4390199190","doi":"10.1002/alz.073726","title":"Association between lipopolysaccharide, immune biomarkers and cerebral amyloid‐beta deposition in older adults with mild cognitive impairment &amp; major depressive disorder","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Baycrest Hospital; Pediatric Oncology Group; Toronto Dementia Research Alliance; University of Toronto; University Health Network; St. Michael's Hospital; Sunnybrook Health Science Centre; Sunnybrook Hospital","funders":"","keywords":"Internal medicine; Medicine; Cognitive decline; Lipopolysaccharide binding protein; Major depressive disorder; C-reactive protein; Depression (economics); Proinflammatory cytokine; Immunology; Inflammation; Endocrinology; Gastroenterology; Acute-phase protein; Dementia; Disease","score_opus":0.0150585796854637,"score_gpt":0.2525541496847779,"score_spread":0.2374955699993142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390199190","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993423,0.0040574945,0.00011264318,0.0008045135,0.00012869811,0.0010739722,0.000090236324,0.00015992243,0.00014953391],"genre_scores_gemma":[0.9990358,0.00013150937,0.000106029984,0.00026279496,0.00004025718,0.00018301522,0.00016894855,0.00004591688,0.000025777063],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99765843,0.00020563984,0.00038230408,0.0007007309,0.000450623,0.00060227583],"domain_scores_gemma":[0.99909616,0.00027844915,0.0002609681,0.00019997054,0.000051343126,0.00011312333],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020382952,0.00029433623,0.00026685625,0.00028683338,0.00026096177,0.00011838219,0.00018422047,0.00013121747,0.00009859222],"category_scores_gemma":[0.00006313477,0.0002737266,0.000074647614,0.00065389904,0.000094254545,0.00041917,0.00016005339,0.00019741991,0.00011775365],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007166099,0.0005033496,0.94389015,0.000044319593,0.006126939,0.00003903815,0.0029759905,0.000010727953,0.014503979,0.000076676515,0.0012280671,0.029884128],"study_design_scores_gemma":[0.005806655,0.00013352829,0.84304035,0.0001662864,0.0021017375,0.0000036066804,0.0007616471,0.00010582154,0.14733894,0.00007316098,0.000032393396,0.0004358465],"about_ca_topic_score_codex":0.000757683,"about_ca_topic_score_gemma":0.0010395442,"teacher_disagreement_score":0.13283497,"about_ca_system_score_codex":0.000020957948,"about_ca_system_score_gemma":0.000033525535,"threshold_uncertainty_score":0.9999715},"labels":[],"label_agreement":null},{"id":"W4390222402","doi":"10.1016/j.nsa.2023.103342","title":"Immuno-metabolic depression features predicting antidepressant treatment outcomes: a pooled analysis of iSPOT-D, CO-MED, EMBARC and Genome-based therapeutic drugs for depression clinical trials","year":2023,"lang":"en","type":"article","venue":"Neuroscience Applied","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NOSM University; Women and Children’s Health Research Institute; University of Alberta; Dalhousie University","funders":"","keywords":"Antidepressant; Depression (economics); Clinical trial; Medicine; Psychiatry; Oncology; Internal medicine; Anxiety","score_opus":0.09974257035641472,"score_gpt":0.4071844004872383,"score_spread":0.3074418301308236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390222402","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950975,0.00031202097,0.001320747,0.00017813784,0.00034333754,0.0020129092,0.00023778668,0.00028346587,0.00021406589],"genre_scores_gemma":[0.9974174,0.0005537558,0.00011797443,0.0012990894,0.00004557021,0.0003766055,0.000032123444,0.000045655852,0.000111810914],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9949793,0.0007249348,0.0012646042,0.0015207381,0.0007911094,0.0007192718],"domain_scores_gemma":[0.9931021,0.0049917903,0.000799391,0.00082804274,0.000044971475,0.00023373433],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002493446,0.00044469515,0.0014641939,0.0008758174,0.00057205115,0.00016723375,0.00070063537,0.00018942235,0.000015014246],"category_scores_gemma":[0.0024756717,0.00030770825,0.0006690218,0.0023121992,0.0005787459,0.00016714334,0.00015866873,0.00022133195,0.000005326191],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058185967,0.00036626242,0.048763055,0.000026974907,0.00008902857,0.000005007859,0.00033441195,0.0017614339,0.9195055,0.00012001077,0.00002054717,0.028425908],"study_design_scores_gemma":[0.0044296077,0.00020148754,0.7187481,0.000017573806,0.0007341298,0.0000015657613,0.00022127392,0.017272543,0.25742638,0.00011010384,0.00052737555,0.00030987296],"about_ca_topic_score_codex":0.00002854052,"about_ca_topic_score_gemma":0.0000054906022,"teacher_disagreement_score":0.66998506,"about_ca_system_score_codex":0.00002268626,"about_ca_system_score_gemma":0.00013097003,"threshold_uncertainty_score":0.9999375},"labels":[],"label_agreement":null},{"id":"W4390223835","doi":"10.1016/j.nsa.2023.102934","title":"Minocycline treatment improves cognitive and functional plasticity in a preclinical mouse model of major depressive disorder","year":2023,"lang":"en","type":"article","venue":"Neuroscience Applied","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Minocycline; Major depressive disorder; Neuroplasticity; Neuroscience; Cognition; Preclinical research; Animal model; Psychology; Medicine; Internal medicine; Biology","score_opus":0.0679947035001991,"score_gpt":0.30809682821237466,"score_spread":0.24010212471217557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390223835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99764526,0.000006072378,0.0011122718,0.000121512865,0.00007526062,0.0005084586,0.000099461744,0.00008241544,0.00034930007],"genre_scores_gemma":[0.99883705,0.00007794432,0.000045742767,0.00046583015,0.0000144031565,0.00014603388,0.000003422796,0.000014927375,0.00039465778],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99823207,0.00004231432,0.00029792823,0.00076804275,0.00030953618,0.00035010252],"domain_scores_gemma":[0.9988689,0.00077201676,0.00011002861,0.00013082189,0.00001663954,0.000101585305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007125466,0.00018243735,0.00023202007,0.00018108873,0.0001299253,0.000031007523,0.0001551613,0.00006621764,0.0000069401335],"category_scores_gemma":[0.00079887745,0.00015281019,0.000046654186,0.0005830735,0.00064761133,0.00013149252,0.00014456264,0.00012787255,0.000012683617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026908622,0.00035161994,0.0012074318,0.0000103917955,0.0000011639524,0.000003917012,0.00019359517,0.0024532902,0.9919148,0.0006704103,0.000013169146,0.0029111106],"study_design_scores_gemma":[0.004260873,0.0002915398,0.073787756,0.000010282027,0.000012925559,0.000002797815,0.00017914924,0.13945585,0.78026223,0.0014678392,0.000022129545,0.00024661972],"about_ca_topic_score_codex":0.000015015138,"about_ca_topic_score_gemma":0.000042900967,"teacher_disagreement_score":0.21165258,"about_ca_system_score_codex":0.000012106349,"about_ca_system_score_gemma":0.00007729957,"threshold_uncertainty_score":0.6231418},"labels":[],"label_agreement":null},{"id":"W4390224466","doi":"10.1016/j.nsa.2023.103920","title":"Ketamine promptly normalises excess norepinephrine and enhances dopamine neuronal activity in Wistar Kyoto rats","year":2023,"lang":"en","type":"article","venue":"Neuroscience Applied","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Dopamine; Ketamine; Norepinephrine; Anesthesia; Pharmacology; Neuroscience; Chemistry; Medicine; Psychology","score_opus":0.031990602673547835,"score_gpt":0.27318305746630334,"score_spread":0.2411924547927555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390224466","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99595416,0.00000950116,0.00005340931,0.00052250695,0.0003237171,0.0006237657,0.00002613675,0.00030815531,0.002178674],"genre_scores_gemma":[0.99764323,0.00014210457,0.000025028456,0.0015661619,0.000059906277,0.00014099856,0.0000036781287,0.000029009234,0.0003898613],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969913,0.000092647395,0.00030076265,0.0012196327,0.0006322626,0.0007634254],"domain_scores_gemma":[0.999003,0.00029309947,0.00013234772,0.00037602984,0.000015904488,0.00017965354],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027484066,0.00031665465,0.00031184911,0.00036941905,0.00028299296,0.0001768078,0.0006194692,0.000060837006,0.00002358216],"category_scores_gemma":[0.00045636963,0.00028992997,0.000038051163,0.0026684634,0.0007665631,0.0005360393,0.00036693623,0.0002916221,0.00005056296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000086847125,0.0001317466,0.0009433635,0.000037557526,3.12609e-7,0.000065375614,0.00010265761,0.00011582667,0.9930238,0.0007829025,0.00010917403,0.004600398],"study_design_scores_gemma":[0.0006672565,0.00011775045,0.2808673,0.000010620175,0.000001885705,0.000014056661,0.000033555905,0.0015416932,0.7139933,0.0002885429,0.002174838,0.00028916818],"about_ca_topic_score_codex":0.00003757505,"about_ca_topic_score_gemma":0.00007660957,"teacher_disagreement_score":0.27992395,"about_ca_system_score_codex":0.00001945934,"about_ca_system_score_gemma":0.00005964959,"threshold_uncertainty_score":0.9999553},"labels":[],"label_agreement":null},{"id":"W4390241686","doi":"10.1016/j.nsa.2023.103573","title":"Association between immune cells and dopamine release in healthy subjects and patients with psychosis","year":2023,"lang":"en","type":"article","venue":"Neuroscience Applied","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas College","funders":"","keywords":"Psychosis; Dopamine; Association (psychology); Immune system; Medicine; Psychology; Psychiatry; Neuroscience; Immunology; Psychotherapist","score_opus":0.015232542969133553,"score_gpt":0.24171733791663863,"score_spread":0.22648479494750506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390241686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99840504,0.0000059202252,0.000008595048,0.0005600611,0.0001143157,0.00043307888,0.000019254965,0.00010000814,0.00035372635],"genre_scores_gemma":[0.9986078,0.00012207037,0.000019363839,0.0010883325,0.0000138442465,0.00003197765,0.000002909808,0.000016235008,0.000097479104],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99825644,0.000056376954,0.00019564111,0.0006442861,0.00041364232,0.00043359047],"domain_scores_gemma":[0.99929297,0.0002766347,0.00012273519,0.00017275712,0.000012105968,0.00012279277],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002108375,0.00014442684,0.0001742196,0.00021109225,0.00019244601,0.000085420514,0.000167518,0.00005361724,0.000002360252],"category_scores_gemma":[0.00020024898,0.0001275497,0.000011794678,0.0014139564,0.00015736876,0.00017016847,0.00008441515,0.00016699218,0.000018134771],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026789698,0.00020697739,0.45189115,0.00005441094,0.0000014015153,0.000009790255,0.00038630835,0.000032800926,0.5355372,0.00027485477,0.00026494064,0.011072308],"study_design_scores_gemma":[0.00165552,0.00023516019,0.96112865,0.000008657832,0.000003114769,3.3362147e-7,0.000031775315,0.00010593186,0.036115874,0.000112748436,0.0004432193,0.00015903151],"about_ca_topic_score_codex":0.000021239824,"about_ca_topic_score_gemma":0.00001476255,"teacher_disagreement_score":0.50923747,"about_ca_system_score_codex":0.000032562024,"about_ca_system_score_gemma":0.00002077119,"threshold_uncertainty_score":0.5201326},"labels":[],"label_agreement":null},{"id":"W4390267413","doi":"10.17691/stm2023.15.6.01","title":"Identification of Diagnostic Schizophrenia Biomarkers Based on the Assessment of Immune and Systemic Inflammation Parameters Using Machine Learning Modeling","year":2023,"lang":"en","type":"article","venue":"Sovremennye tehnologii v medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"","keywords":"Identification (biology); Schizophrenia (object-oriented programming); Inflammation; Systemic inflammation; Immune system; Machine learning; Artificial intelligence; Medicine; Computer science; Computational biology; Immunology; Biology; Psychiatry","score_opus":0.05077927393925695,"score_gpt":0.29861419839229697,"score_spread":0.24783492445304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390267413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99219894,0.0001671749,0.0053445795,0.0014700384,0.0001617803,0.00048045802,0.0000055910964,0.000116407246,0.00005499959],"genre_scores_gemma":[0.99945074,0.0002513963,0.00018205043,0.000042025214,0.000014021725,0.000025048963,0.000010622338,0.000015971356,0.000008094916],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99810565,0.0003175993,0.0006533944,0.00029794627,0.00042446307,0.00020094849],"domain_scores_gemma":[0.9972337,0.0018971738,0.0004639243,0.0003207676,0.0000529916,0.000031482083],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013241756,0.0001516395,0.00026677744,0.00040729516,0.00016481297,0.000012125544,0.00023121935,0.000071339404,0.000013408378],"category_scores_gemma":[0.0071011456,0.00010260644,0.000045438952,0.0008563567,0.0003689308,0.00007273357,0.000057571906,0.00020777901,0.000002538265],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042774383,0.000018169718,0.0022567892,0.00013848754,0.000015570675,0.000002427818,0.00016576618,0.057742424,0.9363419,0.0009096274,0.000003904065,0.0023621721],"study_design_scores_gemma":[0.0009448046,0.00018251258,0.0036402468,0.00043292268,0.000029948233,0.0000027498138,0.0009988463,0.9054797,0.087619714,0.0005788955,0.0000013142208,0.00008829948],"about_ca_topic_score_codex":0.00007286942,"about_ca_topic_score_gemma":0.0000038538897,"teacher_disagreement_score":0.84872216,"about_ca_system_score_codex":0.00004558877,"about_ca_system_score_gemma":0.000043389286,"threshold_uncertainty_score":0.8501248},"labels":[],"label_agreement":null},{"id":"W4390843146","doi":"10.1016/j.bbi.2023.12.018","title":"Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms","year":2024,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Science Foundation Ireland; Wellcome Trust","keywords":"Global Assessment of Functioning; Psychosis; Internal medicine; Haptoglobin; Psychosocial; Schizophrenia (object-oriented programming); Cohort; Logistic regression; Psychology; Positive and Negative Syndrome Scale; Clinical psychology; Medicine; Psychiatry","score_opus":0.03140758472982735,"score_gpt":0.33503679358639255,"score_spread":0.3036292088565652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390843146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99892694,0.0002488758,0.00002699555,0.00008073787,0.00024879526,0.0002443872,0.00016289999,0.000027044684,0.00003331172],"genre_scores_gemma":[0.9992097,0.0005954338,0.00005310268,0.000039330112,0.00002103826,0.000011356129,0.000008191457,0.000009166875,0.000052659405],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9980362,0.00069580507,0.000524322,0.00035048003,0.0002323456,0.00016085422],"domain_scores_gemma":[0.99839693,0.0011297505,0.00022669048,0.00014395337,0.000026249576,0.000076395096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069077854,0.00013655628,0.000318947,0.00006818695,0.00011817936,0.000047159167,0.000091056085,0.00020142179,0.000038402464],"category_scores_gemma":[0.0007314222,0.00010944457,0.00006226068,0.00021425444,0.0002194658,0.00016539854,0.0001726298,0.00034081074,9.228303e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011106213,0.00033639077,0.96510136,0.000031143245,0.000013621244,0.0000013378738,0.00015321939,3.0431124e-7,0.018172635,0.00008015704,0.00009544311,0.015903318],"study_design_scores_gemma":[0.0016996098,0.0004773426,0.98803043,0.00015010878,0.00008153487,0.0000051688903,0.00007801257,0.00009152834,0.009150617,0.000083101695,0.000037875285,0.00011467723],"about_ca_topic_score_codex":0.00015104834,"about_ca_topic_score_gemma":0.000065636195,"teacher_disagreement_score":0.022929056,"about_ca_system_score_codex":0.00002977538,"about_ca_system_score_gemma":0.000022473723,"threshold_uncertainty_score":0.446302},"labels":[],"label_agreement":null},{"id":"W4390989858","doi":"10.4103/0019-5545.394316","title":"BPSS AWARD","year":2024,"lang":"en","type":"article","venue":"Indian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Psychology","score_opus":0.014992436601778986,"score_gpt":0.27380485551463124,"score_spread":0.2588124189128522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390989858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.950925,0.003747708,0.00041505456,0.021556567,0.015629994,0.00007367333,0.000012460739,0.0000761393,0.007563438],"genre_scores_gemma":[0.99624676,0.0000855538,0.0007370988,0.0015895908,0.000931671,5.354684e-7,1.279386e-7,0.00001978516,0.00038889446],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990678,0.00005452335,0.0002851759,0.00014238701,0.0002574001,0.00019272607],"domain_scores_gemma":[0.9995723,0.00007289109,0.00009301932,0.000112743975,0.000016447155,0.00013263132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016053923,0.000095191645,0.0001172497,0.00026057079,0.00005803436,0.00012072404,0.00030671977,0.000053844185,0.00026536657],"category_scores_gemma":[0.00008544257,0.00007510767,0.00017823285,0.00035109813,0.000066680586,0.00023973589,0.000015355843,0.00035783296,0.00026952729],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028404812,0.0007292685,0.012133917,0.00070325093,0.00017602262,0.0063180868,0.0077531133,0.00011499046,0.089155816,0.1448544,0.58604425,0.15173283],"study_design_scores_gemma":[0.002981035,0.0015434962,0.013594329,0.0017562585,0.00007750343,0.014773238,0.003185434,0.00012569809,0.067663044,0.23668645,0.6564665,0.0011470579],"about_ca_topic_score_codex":8.6738135e-7,"about_ca_topic_score_gemma":0.0000049630166,"teacher_disagreement_score":0.15058577,"about_ca_system_score_codex":0.000018703233,"about_ca_system_score_gemma":0.0002999289,"threshold_uncertainty_score":0.3464318},"labels":[],"label_agreement":null},{"id":"W4391052913","doi":"10.1093/schbul/sbad184","title":"Proteomic Biomarkers for the Prediction of Transition to Psychosis in Individuals at Clinical High Risk: A Multi-cohort Model Development Study","year":2024,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Center for Advancing Translational Sciences; National Health and Medical Research Council; Stanley Medical Research Institute; Science Foundation Ireland; National Institute of Mental Health; Medical Research Council; European Regional Development Fund; Colonial Foundation","keywords":"Psychosis; Cohort; Psychology; Cohort study; Medicine; Psychiatry; Clinical psychology; Internal medicine","score_opus":0.04300186290091657,"score_gpt":0.3086324892963473,"score_spread":0.2656306263954307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391052913","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98473084,0.000042868967,0.008058338,0.002021206,0.00038040956,0.004414588,0.00023433783,0.00010372027,0.000013720184],"genre_scores_gemma":[0.985235,0.000045567293,0.012829983,0.00020949065,0.000044250333,0.0015029951,0.000009094853,0.0000330406,0.00009059049],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9976917,0.0002663899,0.0007060244,0.0007171799,0.00034407544,0.00027466717],"domain_scores_gemma":[0.9990939,0.000420755,0.00009797791,0.00028400484,0.000025300951,0.00007809097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001329491,0.00019631848,0.00024530062,0.00022605508,0.0001851656,0.000051340143,0.00030745045,0.000103684826,0.000055725854],"category_scores_gemma":[0.00039599935,0.00014744773,0.00012719356,0.00043038354,0.0000909806,0.000043406446,0.000072652874,0.00022661305,0.00007566655],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.029202787,0.017837875,0.30437848,0.0011060901,0.0020564778,0.000042449963,0.054839242,0.03755634,0.16068482,0.0010789714,0.07559246,0.315624],"study_design_scores_gemma":[0.010575333,0.00089715206,0.90109384,0.0002770554,0.0001473937,0.0000044878693,0.0005257801,0.045991942,0.035964385,0.00036217718,0.0036437344,0.0005167337],"about_ca_topic_score_codex":0.00007639974,"about_ca_topic_score_gemma":0.000115005045,"teacher_disagreement_score":0.59671533,"about_ca_system_score_codex":0.00007426687,"about_ca_system_score_gemma":0.000092787646,"threshold_uncertainty_score":0.60127443},"labels":[],"label_agreement":null},{"id":"W4391310722","doi":"10.2174/0115672050283199240111111801","title":"Development and Optimization of a Target Engagement Model of BrainIDO Inhibition for Alzheimer’s Disease","year":2023,"lang":"en","type":"article","venue":"Current Alzheimer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Treventis (Canada); University Health Network","funders":"Krembil Foundation","keywords":"Disease; Neuroscience; Psychology; Medicine; Pathology","score_opus":0.4204922019889589,"score_gpt":0.43401527219135533,"score_spread":0.013523070202396403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391310722","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94117004,0.009451376,0.038722023,0.0020379426,0.00052477384,0.0064584333,0.00052256574,0.00029459907,0.00081825204],"genre_scores_gemma":[0.9925807,0.00048019408,0.006415419,0.000026045649,0.00002791154,0.0003163791,0.00009565024,0.000030087003,0.000027600028],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9980052,0.0001835686,0.00034226844,0.00041110162,0.00066832267,0.00038953545],"domain_scores_gemma":[0.99901414,0.00036480403,0.00008997298,0.00020628638,0.0001706561,0.00015416704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010470357,0.00012433967,0.00016208984,0.000441405,0.00021307687,0.0000265359,0.00017536795,0.000035931713,0.000030093339],"category_scores_gemma":[0.00061149837,0.00011972003,0.000056113517,0.0006752749,0.00025945756,0.00015245799,0.00024090217,0.0001582674,0.00001077342],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022888042,0.0035164924,0.00087609666,0.0023034327,0.0004370466,0.000012524306,0.020515293,0.35569555,0.23524445,0.07069242,0.033867672,0.27455023],"study_design_scores_gemma":[0.0013474001,0.000093650575,0.0003474594,0.00013893805,0.000044971603,2.1500469e-7,0.00030135436,0.57957834,0.4106853,0.0035190585,0.0037025525,0.00024074646],"about_ca_topic_score_codex":0.000001249807,"about_ca_topic_score_gemma":6.5616047e-7,"teacher_disagreement_score":0.2743095,"about_ca_system_score_codex":0.0000130118315,"about_ca_system_score_gemma":0.00024734228,"threshold_uncertainty_score":0.48820412},"labels":[],"label_agreement":null},{"id":"W4391340931","doi":"10.3390/psychoactives3010004","title":"The Effects of Psilocybin on Lipopolysaccharide-Induced Inflammation in THP-1 Human Macrophages","year":2024,"lang":"en","type":"article","venue":"Psychoactives","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"Mitacs","keywords":"THP1 cell line; Lipopolysaccharide; Inflammation; Psilocybin; Hallucinogen; Medicine; Immunology; Biology; Pharmacology; Cell culture","score_opus":0.018106489712524175,"score_gpt":0.31095312629004357,"score_spread":0.2928466365775194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391340931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927723,0.00028031928,0.000014696194,0.0005629983,0.0007083478,0.00032248074,0.0000020700409,0.00007975574,0.0052570463],"genre_scores_gemma":[0.9993642,0.00011969652,0.0000052118503,0.00007116675,0.000071199334,0.00004427185,3.7422905e-7,0.000017313287,0.00030656578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989504,0.00015146215,0.00018578688,0.00030884295,0.00020971929,0.00019379561],"domain_scores_gemma":[0.9986391,0.0010411912,0.00005492813,0.00022833367,0.0000079198635,0.000028491262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012292541,0.00012567497,0.0001097744,0.00016362846,0.00011748868,0.00008283642,0.00022936714,0.000048510985,0.000015512305],"category_scores_gemma":[0.0003323423,0.00008665227,0.00006159799,0.0002950318,0.00009829926,0.00016646166,0.000021931344,0.00020576165,0.000055918503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004161213,0.00005405026,0.00004570489,0.000069629714,0.000006281558,0.000009591782,0.0010010457,0.0000022962536,0.93954504,0.02268006,0.000100068035,0.03644465],"study_design_scores_gemma":[0.00028951943,0.00017531966,0.010976132,0.00014246744,0.0000026553237,0.0000011506398,0.00013117163,0.000065450084,0.9803191,0.007494633,0.00030952063,0.000092906506],"about_ca_topic_score_codex":0.00002538778,"about_ca_topic_score_gemma":0.000033338347,"teacher_disagreement_score":0.040774062,"about_ca_system_score_codex":0.000026493648,"about_ca_system_score_gemma":0.00001605377,"threshold_uncertainty_score":0.35335767},"labels":[],"label_agreement":null},{"id":"W4391402405","doi":"10.1111/jpi.12938","title":"Stable indoleamines attenuate stress<b>—</b>A novel paradigm in tryptophan metabolism in plants","year":2024,"lang":"en","type":"article","venue":"Journal of Pineal Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Tryptophan; Melatonin; Metabolism; Tryptophan Metabolism; Biology; Biochemistry; Chemistry; Endocrinology; Amino acid","score_opus":0.11700159025005102,"score_gpt":0.38763563451198296,"score_spread":0.27063404426193194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391402405","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99335206,0.0025353166,0.00006101914,0.002138688,0.00045876176,0.00020271206,0.00004427651,0.000016205433,0.0011909945],"genre_scores_gemma":[0.99777275,0.001148089,0.000073859905,0.000108252585,0.00029685243,0.000008194964,0.0000010893143,0.000028513288,0.0005623711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966767,0.00036423706,0.0006292182,0.0003372468,0.0012454104,0.0007471987],"domain_scores_gemma":[0.99849975,0.00097325357,0.0000857991,0.00018605053,0.00006951421,0.00018566039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001871713,0.00016016653,0.00035325775,0.0017203292,0.00006708316,0.0002342596,0.0006334517,0.0001012046,0.0001034193],"category_scores_gemma":[0.0013891518,0.00012599771,0.000094307834,0.0017224094,0.00017275094,0.0005717612,0.00013084066,0.0014295374,0.000058824473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073987554,0.0011509442,0.00315703,0.0003271048,0.000025051571,0.0040114,0.0025870162,0.0008523141,0.9536603,0.008881312,0.004297405,0.02031021],"study_design_scores_gemma":[0.01031397,0.00083852257,0.20948192,0.00276634,0.000010191255,0.0007435157,0.002894858,0.011028502,0.6797686,0.016753292,0.06453404,0.00086622505],"about_ca_topic_score_codex":0.00016407848,"about_ca_topic_score_gemma":0.00027639206,"teacher_disagreement_score":0.27389172,"about_ca_system_score_codex":0.00012550065,"about_ca_system_score_gemma":0.00042298707,"threshold_uncertainty_score":0.6210708},"labels":[],"label_agreement":null},{"id":"W4391471439","doi":"10.21203/rs.3.rs-3857671/v1","title":"Molecular, physiological and functional features underlying antipsychotic medication use related cortical thinning","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Ottawa; Montreal Neurological Institute and Hospital","funders":"","keywords":"Thinning; Antipsychotic; Neuroscience; Psychology; Medicine; Schizophrenia (object-oriented programming); Biology; Psychiatry; Ecology","score_opus":0.1898745437553195,"score_gpt":0.4192626856843492,"score_spread":0.2293881419290297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391471439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992193,0.0016259569,0.00020243095,0.003302492,0.00051033375,0.00067428173,0.000035272078,0.00028726648,0.0011689813],"genre_scores_gemma":[0.998434,0.00053991907,0.00008876052,0.0002652002,0.00006477998,0.00006918141,0.00006223278,0.000041052186,0.00043487264],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99571246,0.0009766342,0.00028237404,0.0011801277,0.0012936434,0.0005547844],"domain_scores_gemma":[0.9978851,0.0012872758,0.00005763482,0.0004386374,0.00011069994,0.00022062035],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0007362754,0.00024671573,0.00024586462,0.00037557294,0.00036552994,0.0005112592,0.0002877653,0.00049563235,0.00011513345],"category_scores_gemma":[0.0040557943,0.00019981033,0.00012553061,0.00054441986,0.00073430536,0.000093431605,0.0011766413,0.0041302047,0.000092836504],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002979562,0.0003666226,0.00039827655,0.0015976271,0.000089003195,0.0006512922,0.0009482509,0.0009874994,0.8601025,0.11599296,0.013485083,0.0050829556],"study_design_scores_gemma":[0.0013900686,0.000503584,0.5399637,0.0030406339,0.00005372644,0.000188007,0.0010410424,0.023605123,0.019109271,0.40912524,0.0008532933,0.0011263073],"about_ca_topic_score_codex":0.000024670768,"about_ca_topic_score_gemma":0.000002786452,"teacher_disagreement_score":0.84099317,"about_ca_system_score_codex":0.00008844363,"about_ca_system_score_gemma":0.00021769294,"threshold_uncertainty_score":0.99816734},"labels":[],"label_agreement":null},{"id":"W4391597598","doi":"10.1016/j.psychres.2024.115773","title":"Sex differences in plasma proteomic markers in late-life depression","year":2024,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; National Institutes of Health; University of Toronto; National Institute on Aging; BrainsWay; Patient-Centered Outcomes Research Institute; Indivior; Fondation Brain Canada; Centre for Addiction and Mental Health Foundation; National Institute of Mental Health; U.S. Department of Justice","keywords":"Biomarker; Depression (economics); Biological age; Biological pathway; Multiplex; Young adult; Biology; Psychological intervention; Internal medicine; Medicine; Bioinformatics; Physiology; Gerontology; Gene expression; Genetics; Psychiatry; Gene","score_opus":0.07262295162245828,"score_gpt":0.35658187137386366,"score_spread":0.28395891975140536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391597598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862837,0.00054254924,0.0000048006464,0.0032738799,0.0005602566,0.00061099674,0.0000063449606,0.00008553768,0.008631904],"genre_scores_gemma":[0.9978533,0.00017811719,0.0000846064,0.000119395765,0.00007869212,0.00014865966,0.0000010399999,0.000024533962,0.0015116868],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99713933,0.0005998457,0.00025896038,0.00069532474,0.00064720976,0.00065933185],"domain_scores_gemma":[0.99911004,0.0004673001,0.000016090538,0.0002627998,0.000010554118,0.00013322408],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008987286,0.0001396076,0.00016307892,0.00076179474,0.000107083484,0.00019024481,0.0005032093,0.000119539596,0.00029001842],"category_scores_gemma":[0.00051807,0.00011407078,0.00004711516,0.0015430078,0.00018737403,0.0001875044,0.00016116834,0.00096176367,0.0003325566],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005437826,0.00047614198,0.8970776,0.00051306735,0.000007169844,0.00012223386,0.001265657,0.000058260484,0.07113014,0.0021262395,0.008912356,0.01776735],"study_design_scores_gemma":[0.002394785,0.0003200963,0.90362555,0.0012002448,0.000002149911,0.000012251333,0.0013363915,0.04685139,0.0152286645,0.0268043,0.0016008803,0.0006233289],"about_ca_topic_score_codex":0.00017616565,"about_ca_topic_score_gemma":0.00040765718,"teacher_disagreement_score":0.05590148,"about_ca_system_score_codex":0.000058958616,"about_ca_system_score_gemma":0.00034126453,"threshold_uncertainty_score":0.46516714},"labels":[],"label_agreement":null},{"id":"W4391617513","doi":"10.1038/s41586-023-07015-2","title":"Circulating myeloid-derived MMP8 in stress susceptibility and depression","year":2024,"lang":"en","type":"article","venue":"Nature","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":153,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Institute of Mental Health; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Canadian Institutes of Health Research; Leon Levy Foundation; Swiss Cancer Research Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Institutes of Health; National Science Foundation","keywords":"Immune system; Social defeat; Social stress; Immunology; Chronic stress; Major depressive disorder; Context (archaeology); Medicine; Biology; Neuroscience; Amygdala","score_opus":0.013989621895391297,"score_gpt":0.28043842270454206,"score_spread":0.2664488008091508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391617513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956352,0.0020035896,0.000015000393,0.0003420938,0.00031230427,0.00012405055,0.000011583603,0.00011219388,0.0014440008],"genre_scores_gemma":[0.99927706,0.000039292427,0.000053638967,0.0004873909,0.00005600923,0.0000038014039,0.000002115942,0.000010780879,0.00006994014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910796,0.0000618509,0.000095522635,0.000418037,0.00015125312,0.00016535807],"domain_scores_gemma":[0.9996115,0.0001880624,0.0000144794485,0.00013735885,0.000008199441,0.000040394076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000085593856,0.000091088645,0.000082180944,0.00007235293,0.000055198827,0.00007747889,0.00010167244,0.00039231795,0.000046027428],"category_scores_gemma":[0.00055319496,0.000074803276,0.000026792877,0.00028193314,0.000054919758,0.00014278885,0.00006583795,0.0011447783,0.0000071154286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014254274,0.00003327016,0.015920479,0.00014061904,0.0000013058176,0.0001282452,0.0007970253,0.000027057158,0.953173,0.00054759753,0.00028827472,0.028928863],"study_design_scores_gemma":[0.0006929147,0.00002794543,0.3847214,0.00044229397,0.0000046758014,0.000037120913,0.0006449126,0.006601632,0.6000658,0.0046959226,0.0016918757,0.00037348483],"about_ca_topic_score_codex":0.000011139561,"about_ca_topic_score_gemma":0.00008495225,"teacher_disagreement_score":0.3688009,"about_ca_system_score_codex":0.000020489495,"about_ca_system_score_gemma":0.000020176625,"threshold_uncertainty_score":0.4973556},"labels":[],"label_agreement":null},{"id":"W4391650406","doi":"10.3389/fpsyt.2024.1356975","title":"Neuroinflammation and schizophrenia – is there a link?","year":2024,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta; Kingston Health Sciences Centre; Queen's University","funders":"","keywords":"Neuroinflammation; Schizophrenia (object-oriented programming); Psychiatry; Psychology; Neuroscience; Inflammation; Psychosis; Medicine; Schizophrenia spectrum; Internal medicine","score_opus":0.0092700651240414,"score_gpt":0.2376597229547186,"score_spread":0.2283896578306772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391650406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9493874,0.011403176,0.001758511,0.013650407,0.016634341,0.00028195602,0.000016744943,0.00028049503,0.0065869875],"genre_scores_gemma":[0.99026346,0.00077844685,0.0061749932,0.0015945315,0.0003468101,0.000015376709,0.0000016995816,0.000038602677,0.00078608113],"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9990467,0.000051252504,0.00016147536,0.00040746832,0.00013590566,0.00019721163],"domain_scores_gemma":[0.9997171,0.00002801022,0.000023824396,0.00017557947,0.0000036587855,0.000051830368],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007041008,0.00012643114,0.00010690902,0.00021311027,0.000063944266,0.00012821962,0.00014553241,0.000077369594,0.000051336257],"category_scores_gemma":[0.000039449733,0.000116351854,0.000046567635,0.00042203796,0.00008471553,0.00020969499,0.0000322566,0.00023273246,0.000052321924],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002502219,0.00010404773,0.030326877,0.0005452409,0.000022920098,0.00007763616,0.0022747607,0.000020727914,0.010434381,0.04115233,0.62287366,0.2919172],"study_design_scores_gemma":[0.0045288177,0.00033898235,0.122814685,0.00093469,0.000042902037,0.00013335218,0.0015730805,0.052398574,0.014754125,0.5328004,0.26809293,0.0015875035],"about_ca_topic_score_codex":0.0000031804268,"about_ca_topic_score_gemma":0.000007635004,"teacher_disagreement_score":0.49164805,"about_ca_system_score_codex":0.000013729299,"about_ca_system_score_gemma":0.000058922724,"threshold_uncertainty_score":0.4744691},"labels":[],"label_agreement":null},{"id":"W4391693511","doi":"10.1016/j.dscb.2024.100122","title":"Containment of neuroimmune challenge by diosgenin confers amelioration of neurochemical and neurotrophic dysfunctions in ketamine-induced schizophrenia in mice","year":2024,"lang":"en","type":"article","venue":"Brain Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Neurochemical; Pharmacology; Ketamine; Neuroinflammation; Medicine; Neurotrophic factors; Brain-derived neurotrophic factor; Hippocampus; Prefrontal cortex; Internal medicine; Endocrinology; Psychology; Neuroscience; Anesthesia; Inflammation; Receptor","score_opus":0.015301858647505858,"score_gpt":0.25064475231001215,"score_spread":0.2353428936625063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391693511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993256,0.00090112665,0.000063359475,0.0045112586,0.00018803858,0.00055484823,0.00002777957,0.000056836834,0.00044075822],"genre_scores_gemma":[0.9989174,0.00064457714,0.000015464857,0.00027333133,0.000010256508,0.000050870916,0.000009814091,0.000037397724,0.000040868843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997934,0.0003006163,0.0005585825,0.00062020536,0.00027686043,0.0003097684],"domain_scores_gemma":[0.99895805,0.00062824576,0.00010470262,0.00022740777,0.000015521618,0.00006609706],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018022911,0.00024359311,0.00033548198,0.00042315162,0.000040448544,0.000032599957,0.00022376346,0.000109439556,0.000024280303],"category_scores_gemma":[0.0007007276,0.00025684375,0.00008245245,0.00086795224,0.00026122047,0.00020966782,0.00008705422,0.00040481985,0.0000033759968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020255029,0.00034752281,0.00035315787,0.00015085094,0.000005368319,0.000012829902,0.0006384729,0.000054035838,0.9909408,0.0019471267,0.00018900173,0.0051582977],"study_design_scores_gemma":[0.0190385,0.0036879317,0.10202808,0.0008973039,0.000061675506,0.000051217434,0.0041747745,0.024519755,0.83082443,0.008144478,0.004515039,0.0020568366],"about_ca_topic_score_codex":0.00015506682,"about_ca_topic_score_gemma":0.0002371995,"teacher_disagreement_score":0.16011637,"about_ca_system_score_codex":0.000028053291,"about_ca_system_score_gemma":0.00007245873,"threshold_uncertainty_score":0.9999884},"labels":[],"label_agreement":null},{"id":"W4391716711","doi":"10.1038/s41537-024-00440-w","title":"Association study of the complement component C4 gene and suicide risk in schizophrenia","year":2024,"lang":"en","type":"article","venue":"Schizophrenia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Centre for Addiction and Mental Health Foundation","keywords":"Schizophrenia (object-oriented programming); Suicidal ideation; Genetic association; Psychology; Psychiatry; Clinical psychology; Medicine; Poison control; Suicide prevention; Gene; Biology; Genetics; Single-nucleotide polymorphism; Genotype; Medical emergency","score_opus":0.023020384463934777,"score_gpt":0.26977485515124144,"score_spread":0.24675447068730666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391716711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997674,0.0003876366,0.000011039101,0.000496781,0.00047522908,0.00065217906,0.000064860425,0.00006946256,0.00016883286],"genre_scores_gemma":[0.9995119,0.00007669173,0.00011357826,0.00008948615,0.0000520167,0.000027666034,0.0000020210011,0.00001981691,0.0001068317],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9979806,0.00041665015,0.00038516402,0.00045280007,0.0004935025,0.0002712604],"domain_scores_gemma":[0.9991084,0.00036290727,0.00014718126,0.0003104777,0.000018848928,0.00005223057],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004285003,0.00017370337,0.00022255456,0.00016122428,0.00015745236,0.00009256301,0.00029831022,0.00005286086,0.00005306069],"category_scores_gemma":[0.00028449908,0.00012802152,0.00006758451,0.00061429647,0.00006911068,0.00010741887,0.00021670417,0.0003433456,0.000025402207],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001865457,0.0025614148,0.33372623,0.00020063181,0.00021567995,0.00008323951,0.008410716,0.0006730414,0.591997,0.010220643,0.0031139958,0.046931934],"study_design_scores_gemma":[0.004851852,0.0002251501,0.9407496,0.000092854665,0.00004869124,0.0000048168254,0.000494768,0.0018476067,0.047569387,0.0032521375,0.0005964594,0.00026668358],"about_ca_topic_score_codex":0.00039765536,"about_ca_topic_score_gemma":0.0017033856,"teacher_disagreement_score":0.60702336,"about_ca_system_score_codex":0.0000953045,"about_ca_system_score_gemma":0.000052923995,"threshold_uncertainty_score":0.52205664},"labels":[],"label_agreement":null},{"id":"W4391786419","doi":"10.1186/s13293-024-00589-0","title":"Nrf2 activation rescues stress-induced depression-like behaviour and inflammatory responses in male but not female rats","year":2024,"lang":"en","type":"article","venue":"Biology of Sex Differences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Institute of Neurosciences, Mental Health and Addiction; Canadian Institutes of Health Research","keywords":"Antidepressant; Major depressive disorder; Chronic stress; Medicine; Internal medicine; Inflammation; Hippocampal formation; Anxiety; Endocrinology; Depression (economics); Hippocampus; Psychiatry; Amygdala","score_opus":0.049982699159812335,"score_gpt":0.30037064981894956,"score_spread":0.2503879506591372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391786419","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988266,0.00031810472,0.0000044435415,0.00015635329,0.0002126053,0.00016748004,0.000040767398,0.000060887305,0.00021276389],"genre_scores_gemma":[0.9992246,0.00018708034,0.000023386317,0.000077913945,0.000033597313,0.000025926376,0.0000044918543,0.000008656261,0.0004143367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874616,0.00026102632,0.00023728803,0.00044150496,0.000110086316,0.00020394009],"domain_scores_gemma":[0.99900717,0.00072267244,0.000066651635,0.00014780172,0.000013148592,0.000042556225],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013154479,0.00014495735,0.00020106275,0.00022792966,0.00007161576,0.000035996884,0.00018732376,0.00016069168,0.000053215805],"category_scores_gemma":[0.00027930844,0.00011076413,0.00002855669,0.00014155416,0.00029784275,0.00014776386,0.000091902904,0.00016352859,0.0000055881637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009372052,0.00003744032,0.28710726,0.000038203572,0.000002951936,0.000010603911,0.0005284291,2.4376376e-7,0.7064305,0.00021983281,0.00001289835,0.0055179168],"study_design_scores_gemma":[0.00013197563,0.00007238202,0.4370606,0.000093576964,0.0000021233475,0.000003596074,0.00055507384,0.000029907385,0.5616833,0.00026042183,0.000021917584,0.00008511107],"about_ca_topic_score_codex":0.00010450503,"about_ca_topic_score_gemma":0.00007344819,"teacher_disagreement_score":0.14995335,"about_ca_system_score_codex":0.000011045711,"about_ca_system_score_gemma":0.00006251594,"threshold_uncertainty_score":0.451683},"labels":[],"label_agreement":null},{"id":"W4391814047","doi":"10.1002/ajhb.24053","title":"Intimate partner violence, depression, and chronic low‐grade inflammation among middle‐aged women in Cebu, Philippines","year":2024,"lang":"en","type":"article","venue":"American Journal of Human Biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Center for Environmental Health and Susceptibility, University of North Carolina at Chapel Hill; National Institute of Environmental Health Sciences; Office of Extramural Research, National Institutes of Health; National Heart, Lung, and Blood Institute; Fogarty International Center; National Institute on Aging; National Institutes of Health; National Center for Research Resources; Canadian Institute for Advanced Research","keywords":"Medicine; Stressor; Depression (economics); Waist; Population; Demography; Gerontology; Context (archaeology); Mental health; Center for Epidemiologic Studies Depression Scale; Environmental health; Obesity; Clinical psychology; Psychiatry; Internal medicine; Depressive symptoms; Geography; Cognition","score_opus":0.015525343387092813,"score_gpt":0.28009172361734,"score_spread":0.2645663802302472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391814047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986891,0.0006692277,0.000037541606,0.00018951933,0.00015894958,0.00008854778,0.0000022803576,0.00002780138,0.00013704412],"genre_scores_gemma":[0.9989787,0.00063962303,0.000022007407,0.00012808194,0.00016675144,0.0000106267435,0.0000011263705,0.0000134136535,0.000039686194],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986347,0.0002639119,0.00041376046,0.00024994626,0.00009389272,0.00034380573],"domain_scores_gemma":[0.99936,0.00017706433,0.00023684815,0.00010665477,0.000019096942,0.0001002997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031213058,0.00013616956,0.0002946142,0.00036832012,0.000077255936,0.00004895246,0.00021040952,0.00004464031,0.00008568035],"category_scores_gemma":[0.00014378708,0.000101968355,0.000051039333,0.00035211543,0.00082858116,0.00021508517,0.000059250287,0.0002946053,0.000006921119],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057605357,0.000052758787,0.036866594,0.00006856973,0.000019224566,0.00010292879,0.0021898819,0.000047620175,0.88084745,0.0007512254,0.00008135029,0.07891479],"study_design_scores_gemma":[0.0037423307,0.004884406,0.68221486,0.002518662,0.000034121025,0.0006062264,0.0036400522,0.001535888,0.2543737,0.041493587,0.0038291474,0.0011270385],"about_ca_topic_score_codex":0.000015244951,"about_ca_topic_score_gemma":0.000035904628,"teacher_disagreement_score":0.64534825,"about_ca_system_score_codex":0.00007430627,"about_ca_system_score_gemma":0.00005396985,"threshold_uncertainty_score":0.41581488},"labels":[],"label_agreement":null},{"id":"W4391842097","doi":"10.3389/fpsyt.2024.1341666","title":"Risk assessment of psychiatric complications in infectious diseases: CALCulation of prognostic indices on example of COVID-19","year":2024,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Psychopathology; Medicine; Receiver operating characteristic; Internal medicine; Comorbidity; Psychiatry; Anxiety; Depression (economics)","score_opus":0.016239666103475797,"score_gpt":0.31355707823601153,"score_spread":0.2973174121325357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391842097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97379327,0.0013812573,0.018283032,0.0004754707,0.00320903,0.00079389993,0.00020362646,0.00006371885,0.0017966754],"genre_scores_gemma":[0.99646765,0.00017213357,0.0030756416,0.000161853,0.000025542457,0.000057753143,0.000016045715,0.000016386764,0.000006999021],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99836636,0.00022479644,0.0005494007,0.00040022668,0.00028914996,0.0001700667],"domain_scores_gemma":[0.99901533,0.00030073355,0.00028587214,0.00030639052,0.000017944398,0.00007374706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019912596,0.00013509717,0.0002639179,0.0009972808,0.000044504774,0.000014124927,0.00022806994,0.000077441335,0.000015014796],"category_scores_gemma":[0.0003286187,0.00013203586,0.00010355734,0.0017316826,0.00017255703,0.00011479048,0.000028393957,0.00020707678,0.000001434276],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032227923,0.0008425862,0.9748825,0.00061680196,0.000013579071,8.106548e-7,0.0003924172,0.0038300138,0.00016676978,0.013877596,0.0038813814,0.0014633228],"study_design_scores_gemma":[0.0010203109,0.00023751988,0.9541675,0.00015034701,0.000033508037,0.0000012363007,0.00028875642,0.0084163435,0.00008184584,0.03504967,0.00041005874,0.00014289976],"about_ca_topic_score_codex":0.00032577058,"about_ca_topic_score_gemma":0.00017198134,"teacher_disagreement_score":0.022674356,"about_ca_system_score_codex":0.00008970099,"about_ca_system_score_gemma":0.0004367183,"threshold_uncertainty_score":0.5384266},"labels":[],"label_agreement":null},{"id":"W4391843785","doi":"10.1503/jpn.230099","title":"Epigenetic profile of the immune system associated with symptom severity and treatment response in schizophrenia","year":2024,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Lawson Health Research Institute; Western University","funders":"","keywords":"Epigenetics; DNA methylation; Schizophrenia (object-oriented programming); Methylation; Immune system; Biomarker; CpG site; Glutamatergic; Bioinformatics; Biology; Gene; Medicine; Genetics; Psychiatry; Gene expression; Receptor","score_opus":0.013595385263950464,"score_gpt":0.24378046231479547,"score_spread":0.230185077050845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391843785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965517,0.0014025614,0.000015227816,0.0010018355,0.0007941131,0.0001559962,0.000012193212,0.000011743334,0.000054613363],"genre_scores_gemma":[0.9996127,0.00015283837,0.000055761295,0.00007225199,0.000018167211,0.000002315026,2.6169907e-8,0.0000073904894,0.000078554214],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99869347,0.00034020853,0.0003090155,0.00023268267,0.0002647193,0.00015989762],"domain_scores_gemma":[0.9993479,0.00024132078,0.00019832827,0.00013209155,0.000017992037,0.00006232472],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004216657,0.000116800074,0.00018712458,0.00013533953,0.0001252026,0.000071174356,0.000204561,0.000035606463,0.0000017938968],"category_scores_gemma":[0.00024021334,0.0000647047,0.000055192373,0.0006823912,0.0003269253,0.0001745063,0.00003932707,0.00017433394,2.9970792e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003165993,0.00055987044,0.03140744,0.00020488455,0.000012471214,0.0001428441,0.0009296924,0.00015089913,0.9570168,0.003703042,0.000028710676,0.0026773298],"study_design_scores_gemma":[0.0013617186,0.0017407668,0.9110312,0.00090169854,0.000022762177,0.0006020391,0.0002344709,0.0015746718,0.08211116,0.00020769324,0.0000803706,0.00013144719],"about_ca_topic_score_codex":0.0000045266206,"about_ca_topic_score_gemma":0.000014783379,"teacher_disagreement_score":0.8796238,"about_ca_system_score_codex":0.00003413337,"about_ca_system_score_gemma":0.00028243233,"threshold_uncertainty_score":0.2638581},"labels":[],"label_agreement":null},{"id":"W4392004363","doi":"10.1128/msphere.00804-23","title":"Manganese homeostasis modulates fungal virulence and stress tolerance in <i>Candida albicans</i>","year":2024,"lang":"en","type":"article","venue":"mSphere","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université Laval; Montreal Heart Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds de recherche du Québec; Julius-Maximilians-Universität Würzburg; Canada Foundation for Innovation","keywords":"Virulence; Candida albicans; Microbiology; Homeostasis; Biology; Manganese; Cell biology; Chemistry; Genetics","score_opus":0.012082733601356772,"score_gpt":0.24092676604206545,"score_spread":0.22884403244070867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392004363","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903309,0.005719137,0.000025019046,0.00050344435,0.00021242036,0.00014536461,0.00011012046,0.00013119135,0.0028224296],"genre_scores_gemma":[0.9975551,0.0005551531,0.00004852796,0.00056883064,0.000043489108,0.000019694024,0.0000017005832,0.000021582726,0.0011859632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988496,0.000054257383,0.00014468121,0.00048378456,0.00017604158,0.00029168263],"domain_scores_gemma":[0.99956673,0.00015571744,0.000017982302,0.00017949413,0.000006342378,0.000073726675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053839052,0.00015337735,0.00014060449,0.00004955419,0.000064252934,0.00015078136,0.00018425245,0.000058847705,0.00028565002],"category_scores_gemma":[0.000054854507,0.00013675063,0.000035319466,0.00040706256,0.00013653463,0.00024501793,0.00006232286,0.00018387912,0.00006591769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022872248,0.00039949018,0.03434052,0.0013233584,0.000023308685,0.002771318,0.0048841545,0.0017065231,0.50696975,0.008416251,0.006020987,0.4329156],"study_design_scores_gemma":[0.0028503013,0.00033462097,0.12781703,0.0016740533,0.000026504233,0.0002712787,0.003376646,0.035100486,0.7665085,0.007843891,0.05214241,0.0020542792],"about_ca_topic_score_codex":0.00015132346,"about_ca_topic_score_gemma":0.00039455804,"teacher_disagreement_score":0.43086132,"about_ca_system_score_codex":0.00002096821,"about_ca_system_score_gemma":0.000028486797,"threshold_uncertainty_score":0.5576529},"labels":[],"label_agreement":null},{"id":"W4392094574","doi":"10.1016/j.psyneuen.2023.106911","title":"WITHDRAWN: Psychoneuroimmunological characterization in schizophrenia requires health-related adjustments","year":2024,"lang":"en","type":"letter","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Schizophrenia (object-oriented programming); Psychosocial; Medicine; Internal medicine; Etiology; Interleukin 6; Psychiatry; Cytokine","score_opus":0.04073365825876844,"score_gpt":0.2968217547420091,"score_spread":0.25608809648324066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392094574","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08067582,0.001610002,0.000016655235,0.89970577,0.012336057,0.0015698393,0.00031697945,0.0011936331,0.0025752354],"genre_scores_gemma":[0.049684238,0.0043977904,0.000050353035,0.93611985,0.001129605,0.00038812452,0.00073753856,0.00035866347,0.0071338215],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99161786,0.0014879014,0.0015752595,0.002787062,0.0006028287,0.0019291107],"domain_scores_gemma":[0.99770916,0.000306425,0.0006093394,0.0012174901,0.000030618794,0.00012698023],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008547288,0.0010069474,0.0011876973,0.0014616196,0.00019425429,0.00017873631,0.0013262032,0.0007304697,0.00051028567],"category_scores_gemma":[0.00031001895,0.0009646505,0.00030227646,0.0015287403,0.0006218141,0.00025585984,0.0003071788,0.0057760663,0.0032350433],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053225097,0.00046472665,0.00010481047,0.00040489086,0.000060730814,0.014221236,0.0002502234,0.0000029097391,0.05767774,0.0016404149,0.90853935,0.016100705],"study_design_scores_gemma":[0.0031494724,0.00083427114,0.01060195,0.00032237638,0.000021994947,0.002873035,0.0000135049295,0.000055126944,0.0013217487,0.005111296,0.9745921,0.0011031465],"about_ca_topic_score_codex":0.000030671923,"about_ca_topic_score_gemma":0.000010933829,"teacher_disagreement_score":0.06605271,"about_ca_system_score_codex":0.00016283809,"about_ca_system_score_gemma":0.00016680891,"threshold_uncertainty_score":0.9992804},"labels":[],"label_agreement":null},{"id":"W4392094900","doi":"10.1016/j.psyneuen.2023.106785","title":"Psychoneuroimmunological characterization in schizophrenia requires health-related adjustments","year":2024,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Schizophrenia (object-oriented programming); Characterization (materials science); Psychology; Psychiatry; Nanotechnology; Materials science","score_opus":0.039837963166100394,"score_gpt":0.31220524441571695,"score_spread":0.27236728124961657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392094900","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97530293,0.0013615658,0.00011335527,0.0146429865,0.0048719575,0.0005671881,0.000044488283,0.0009165507,0.0021789433],"genre_scores_gemma":[0.9929881,0.002359129,0.00004749156,0.0036243063,0.00006747037,0.00008584607,0.000034081815,0.00005685293,0.0007366875],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9964643,0.0005826736,0.0007033798,0.0011634286,0.0002258199,0.00086038327],"domain_scores_gemma":[0.9991333,0.00019460486,0.00011016548,0.0004427557,0.0000109589655,0.00010825206],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007019949,0.00031058642,0.00035753674,0.00063042244,0.000120644385,0.00009277914,0.00046082333,0.00008816077,0.0003819389],"category_scores_gemma":[0.00021608891,0.00029168115,0.000107574466,0.001208026,0.00025000886,0.00030507866,0.00009859873,0.00068755593,0.0012244266],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047390963,0.0005441998,0.0006402405,0.000081064136,0.00001643428,0.0015069304,0.00036084716,0.00000863364,0.830735,0.041804742,0.0019422164,0.121885784],"study_design_scores_gemma":[0.01016331,0.0024771718,0.73811597,0.0004641742,0.00001815039,0.0056451526,0.00013435674,0.0023972425,0.047048606,0.02848323,0.16320981,0.0018428571],"about_ca_topic_score_codex":0.000013445894,"about_ca_topic_score_gemma":0.0000075865983,"teacher_disagreement_score":0.7836864,"about_ca_system_score_codex":0.0000598462,"about_ca_system_score_gemma":0.00006078163,"threshold_uncertainty_score":0.9999535},"labels":[],"label_agreement":null},{"id":"W4392108261","doi":"10.3389/fphar.2024.1368620","title":"Intravenous Reelin rescues despair-like behavior, Reelin cells in the dentate sub-granular zone, and spleen atrophy in the cyclic corticosterone model of recurring depressive episodes","year":2024,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Reelin; Dentate gyrus; Behavioural despair test; Chronic stress; Atrophy; White pulp; Hippocampus; Medicine; Hippocampal formation; Internal medicine; Spleen; Endocrinology; Psychology; Antidepressant; Receptor","score_opus":0.02170258928122098,"score_gpt":0.277788384003489,"score_spread":0.256085794722268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392108261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914264,0.0038320106,0.0020573067,0.0005614227,0.0009947682,0.0010008881,0.000038865695,0.000031110074,0.00005722396],"genre_scores_gemma":[0.9943154,0.003314229,0.0007867425,0.0012768762,0.000041487478,0.00021181836,0.000003935143,0.000029611096,0.0000199372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970495,0.0009919341,0.0005589643,0.00059385155,0.00026923273,0.00053652143],"domain_scores_gemma":[0.9991421,0.0004174052,0.00010895991,0.0002681669,0.000014332668,0.000049022725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006756151,0.00024202657,0.00035704565,0.0004302126,0.00008203561,0.000058202357,0.000697955,0.0001327512,0.000007786509],"category_scores_gemma":[0.00006386538,0.000179828,0.00007244849,0.0006564895,0.0004728385,0.00019136844,0.00013371189,0.00070672616,0.000003785839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005660978,0.0005735526,0.016279485,0.0001530102,0.000019896064,0.0012905337,0.012485767,0.0046699173,0.94173104,0.0001352953,0.0051551573,0.016940227],"study_design_scores_gemma":[0.00773687,0.0007912718,0.036171656,0.00033167584,0.00031924478,0.00022776297,0.005727835,0.17770372,0.761176,0.0073574153,0.0013854783,0.0010710768],"about_ca_topic_score_codex":0.00019127267,"about_ca_topic_score_gemma":0.00035817295,"teacher_disagreement_score":0.18055506,"about_ca_system_score_codex":0.00007307354,"about_ca_system_score_gemma":0.000056179037,"threshold_uncertainty_score":0.73331726},"labels":[],"label_agreement":null},{"id":"W4392208188","doi":"10.1016/b978-0-443-15589-5.00001-3","title":"Tryptophan and its role in sleep and mood","year":2024,"lang":"en","type":"book-chapter","venue":"Studies in natural products chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Child, Adolescent and Family Mental Health","funders":"","keywords":"Mood; Sleep (system call); Psychology; Psychiatry; Computer science; Programming language","score_opus":0.023258047822184425,"score_gpt":0.26788274757634073,"score_spread":0.2446246997541563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392208188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3698586,0.31250414,6.186786e-9,0.0022028207,0.0010527615,0.0006665686,0.000055467855,0.00014368036,0.31351593],"genre_scores_gemma":[0.788561,0.0076763164,0.000010461082,0.00011035017,0.00025795228,0.000015701036,0.0000048679854,0.000045563655,0.20331779],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978894,0.000010437787,0.00031829518,0.0012063717,0.00023701887,0.00033848747],"domain_scores_gemma":[0.9994524,0.00012421673,0.00008552039,0.00025178568,0.00004040221,0.000045660818],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000100588666,0.00045020992,0.0004850493,0.00010251574,0.00006760894,0.000041175357,0.00020546356,0.00023969391,0.000016388938],"category_scores_gemma":[0.00077631354,0.00039751668,0.0000399811,0.00013939133,0.0004468928,0.00010056656,0.0005330952,0.0010587774,0.000013760919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017846555,0.0000843711,0.000041587064,0.009116352,0.00014567797,0.0007050022,0.0036910297,0.000002512893,0.9559348,0.01836298,0.0018644196,0.009872773],"study_design_scores_gemma":[0.0015922587,0.00005642278,0.00012147466,0.0018676057,0.000048633643,0.00022659545,0.0010142985,0.00011865603,0.88843995,0.07859833,0.026304651,0.001611114],"about_ca_topic_score_codex":0.0000013384764,"about_ca_topic_score_gemma":0.000010197926,"teacher_disagreement_score":0.4187024,"about_ca_system_score_codex":0.00008480022,"about_ca_system_score_gemma":0.000028449922,"threshold_uncertainty_score":0.99984765},"labels":[],"label_agreement":null},{"id":"W4392229214","doi":"10.1101/2024.02.25.580567","title":"Effects of prenatal maternal immune activation and exposure to circadian disruption during adolescence: exploring the two-hit model of neurodevelopmental disorders","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Centre hospitalier universitaire Sainte-Justine; Natural Sciences and Engineering Research Council of Canada; McGill University; Velux Stiftung","keywords":"Circadian rhythm; Autism; Offspring; Neurodevelopmental disorder; Hippocampal formation; Immune system; Biology; Neuroscience; Physiology; Psychology; Pregnancy; Immunology; Genetics; Developmental psychology","score_opus":0.013530396160454383,"score_gpt":0.21280348310722055,"score_spread":0.19927308694676618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392229214","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972784,0.00019843783,0.000523643,0.00012315159,0.00064283033,0.0010218058,0.00007025429,0.000138683,0.0000028177717],"genre_scores_gemma":[0.99898994,0.0002308801,0.00032234762,0.000047522415,0.00006773754,0.00024814604,1.1334166e-7,0.00008997319,0.0000033310366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976793,0.00014385176,0.0005016616,0.000839777,0.00045387834,0.00038156428],"domain_scores_gemma":[0.9988888,0.00010852627,0.00029204515,0.0005143676,0.00006325604,0.00013302895],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022843892,0.00041323534,0.00037102128,0.00033178154,0.00015376134,0.00012834066,0.0005168023,0.00013442403,0.00000293717],"category_scores_gemma":[0.000300551,0.00037547344,0.00011229443,0.00046978667,0.00017846284,0.00024030489,0.0008996894,0.00058097095,0.0000054404527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000919151,0.000072285875,0.0017023676,0.002338677,0.000024275198,0.0000059078416,0.00023224224,0.0019287756,0.9932249,0.00034420265,0.0000012177583,0.000033191103],"study_design_scores_gemma":[0.00034695998,0.000030105595,0.29060644,0.0010493528,0.000020600384,2.5027708e-8,0.000008359401,0.00086433213,0.706805,0.000010942172,0.0000018222105,0.0002560889],"about_ca_topic_score_codex":0.00003631168,"about_ca_topic_score_gemma":0.0000021818282,"teacher_disagreement_score":0.28890407,"about_ca_system_score_codex":0.000102504026,"about_ca_system_score_gemma":0.00016835849,"threshold_uncertainty_score":0.9998697},"labels":[],"label_agreement":null},{"id":"W4392231952","doi":"10.3390/cells13050423","title":"Role of Inflammatory Mechanisms in Major Depressive Disorder: From Etiology to Potential Pharmacological Targets","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":184,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; University of British Columbia","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Neuroinflammation; Inflammation; Dysbiosis; Medicine; Excitotoxicity; Gut–brain axis; Gut flora; Major depressive disorder; Antidepressant; Vitamin D and neurology; Neurochemical; Immunology; Bioinformatics; Glutamate receptor; Biology; Internal medicine; Amygdala; Receptor","score_opus":0.0183908899584705,"score_gpt":0.29187320240102244,"score_spread":0.27348231244255194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392231952","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016651218,0.99495775,0.0001559227,0.000039083996,0.0010998735,0.0012079688,0.00035592128,0.000080247504,0.00043809245],"genre_scores_gemma":[0.003907308,0.9950204,0.00017347584,0.00024208898,0.000120260716,0.00022404894,0.000034046236,0.00006150665,0.00021685127],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974233,0.00043268563,0.00062678225,0.0008811108,0.00021815304,0.0004179853],"domain_scores_gemma":[0.999089,0.00028667058,0.00021398607,0.00026662162,0.000014202679,0.00012954029],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000101796235,0.0004069711,0.0011324764,0.00029045704,0.00004022074,0.000028069462,0.00072595646,0.00043540174,0.00067574816],"category_scores_gemma":[0.00010429953,0.00032414668,0.0003755186,0.00036683973,0.000116993586,0.00004658017,0.00045152823,0.00056100363,0.000977762],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005905159,0.00033725062,0.0000010632873,0.0032922998,0.00009199668,0.00046743176,0.00026013586,0.000059638547,0.4484656,0.0011957623,0.0022674452,0.54350233],"study_design_scores_gemma":[0.00078170066,0.0001400792,0.000010994396,0.0019057578,0.00048696608,0.0000121924695,0.000059367234,0.000063817584,0.09451612,0.010211661,0.891028,0.0007833614],"about_ca_topic_score_codex":0.000023582897,"about_ca_topic_score_gemma":0.000016940783,"teacher_disagreement_score":0.8887605,"about_ca_system_score_codex":0.000046979305,"about_ca_system_score_gemma":0.0001342257,"threshold_uncertainty_score":0.9999211},"labels":[],"label_agreement":null},{"id":"W4392247067","doi":"10.1016/j.bbi.2024.02.030","title":"Neopterin, kynurenine metabolites, and indexes related to vitamin B6 are associated with post-stroke cognitive impairment: The Nor-COAST study","year":2024,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Nasjonalforeningen for Folkehelsen; Helse Midt-Norge","keywords":"Neopterin; Montreal Cognitive Assessment; Kynurenine; Internal medicine; Medicine; Stroke (engine); Prospective cohort study; Dementia; Physical therapy; Gastroenterology; Disease; Tryptophan; Biology","score_opus":0.015380583546678676,"score_gpt":0.2662436349503849,"score_spread":0.25086305140370624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392247067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964987,0.0005282305,0.000003163375,0.00068045984,0.00011443155,0.0012807391,0.00064018485,0.00016058171,0.00009348251],"genre_scores_gemma":[0.99761784,0.00004213683,0.000005672133,0.00072938914,0.0000106302705,0.00014671992,0.000028117654,0.000035422672,0.0013840625],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99811465,0.00052336894,0.00024688028,0.00047304027,0.00028479664,0.00035724498],"domain_scores_gemma":[0.9987116,0.00074393186,0.00007483077,0.0002566306,0.0000741769,0.00013883071],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041302308,0.00029522288,0.00027945577,0.00017359141,0.0004999402,0.00032003858,0.00021932219,0.00008605949,0.000053273034],"category_scores_gemma":[0.0006085078,0.00019626548,0.000055733522,0.00058686605,0.00029154404,0.00024415622,0.00025380024,0.0005265897,0.000010592687],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007763938,0.003966927,0.4268542,0.00006275112,0.00025702443,0.0005628812,0.03978459,0.000001769069,0.46846688,0.00019622566,0.0005100083,0.058560345],"study_design_scores_gemma":[0.0014628145,0.0012502434,0.97993016,0.00012216126,0.00014707808,0.00006207163,0.0087008225,0.000008987691,0.007818502,0.000013065799,0.0001997931,0.000284286],"about_ca_topic_score_codex":0.00034632385,"about_ca_topic_score_gemma":0.0006905884,"teacher_disagreement_score":0.55307597,"about_ca_system_score_codex":0.000023092209,"about_ca_system_score_gemma":0.000040336712,"threshold_uncertainty_score":0.8003474},"labels":[],"label_agreement":null},{"id":"W4392595406","doi":"10.1016/j.bbi.2024.03.014","title":"Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain","year":2024,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Helse Sør-Øst RHF; Norges Forskningsråd; Universitetet i Oslo; CMC Microsystems","keywords":"Neuroinflammation; Cognitive decline; Cognition; Inflammation; Immunology; Psychology; Biology; Medicine; Neuroscience; Dementia; Internal medicine; Disease","score_opus":0.02490862395497095,"score_gpt":0.28847353273870624,"score_spread":0.2635649087837353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392595406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99772316,0.00041566032,0.000011073623,0.0006267053,0.00013365032,0.00051987363,0.0002844046,0.000099515615,0.00018594434],"genre_scores_gemma":[0.9986582,0.000036205245,0.000035783592,0.001074928,0.000018151428,0.000060693634,0.00002174563,0.000025990714,0.00006833159],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985964,0.00023899555,0.00023504246,0.00047183415,0.00016529812,0.00029247592],"domain_scores_gemma":[0.9990857,0.0006198321,0.000021388292,0.00013720973,0.000009199793,0.00012662474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000246824,0.00021561891,0.00019223598,0.00016326197,0.0002607853,0.00018001274,0.0001401999,0.00010295472,0.00007018803],"category_scores_gemma":[0.00029419825,0.00021804283,0.000051604587,0.00028097106,0.00017711055,0.0003195519,0.00014109685,0.0003589636,0.000010991585],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071427516,0.0001800459,0.039709754,0.000049197235,0.000010102461,0.00011535863,0.016530516,3.3016568e-7,0.8977727,0.00010360607,0.000092587354,0.04536436],"study_design_scores_gemma":[0.0021576358,0.00018098894,0.7384053,0.0003514151,0.00003988068,0.00009160741,0.0040480234,0.000059286736,0.25332177,0.0002461066,0.0005131326,0.0005848639],"about_ca_topic_score_codex":0.00029060818,"about_ca_topic_score_gemma":0.00042616026,"teacher_disagreement_score":0.69869554,"about_ca_system_score_codex":0.000019916612,"about_ca_system_score_gemma":0.00003285358,"threshold_uncertainty_score":0.8891529},"labels":[],"label_agreement":null},{"id":"W4392763481","doi":"10.1007/s11357-024-01110-6","title":"Resistance exercise effects on hippocampus subfield volumes and biomarkers of neuroplasticity and neuroinflammation in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial","year":2024,"lang":"en","type":"article","venue":"GeroScience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Lietuvos Mokslo Taryba","keywords":"Subiculum; Neuroinflammation; Internal medicine; Hippocampal formation; Medicine; Hippocampus; Montreal Cognitive Assessment; Dentate gyrus; Psychology; Endocrinology; Supramarginal gyrus; Oncology; Neuroscience; Functional magnetic resonance imaging; Inflammation; Dementia","score_opus":0.003709309431164652,"score_gpt":0.20901264847964227,"score_spread":0.2053033390484776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392763481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957795,0.0004080879,0.00016272269,0.00006914535,0.00019328606,0.0033019052,0.00001812219,0.00002640645,0.00004080605],"genre_scores_gemma":[0.9990916,0.00065203995,0.000043251424,0.000042992717,0.000008486846,0.000121799705,3.900222e-7,0.000009832484,0.000029587936],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9981208,0.00043605705,0.00035490867,0.0005708927,0.00030905468,0.00020831033],"domain_scores_gemma":[0.9949897,0.0045953547,0.00020611884,0.000107521184,0.000029604726,0.00007172592],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056782144,0.00018457352,0.0006182396,0.0002347208,0.00007840576,0.000069611815,0.00008266332,0.000049762806,0.0000024407618],"category_scores_gemma":[0.0023608452,0.00012807002,0.000052710624,0.0004467267,0.00089983444,0.00019944359,0.000042108724,0.00012657585,3.5370437e-7],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.97322196,0.00015657354,0.00062060094,0.00075641996,0.000012836136,0.000036694873,0.0015704683,0.000008451297,0.018275287,0.00016509605,0.000008883696,0.005166755],"study_design_scores_gemma":[0.87228924,0.0012117972,0.03630293,0.0031348506,0.00009240018,0.000005356926,0.00014320061,0.010926736,0.07514862,0.0005199325,2.7904326e-7,0.00022466698],"about_ca_topic_score_codex":0.000043729513,"about_ca_topic_score_gemma":0.00004294223,"teacher_disagreement_score":0.1009327,"about_ca_system_score_codex":0.000006402431,"about_ca_system_score_gemma":0.000044352717,"threshold_uncertainty_score":0.5222544},"labels":[],"label_agreement":null},{"id":"W4392810755","doi":"10.1101/2024.03.13.583894","title":"Transcriptional and neurochemical signatures of cerebral blood flow alterations in schizophrenia and the clinical high-risk state for psychosis","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Montreal Neurological Institute and Hospital","funders":"Medical Research Council","keywords":"Neurochemical; Neuroscience; Schizophrenia (object-oriented programming); Psychosis; Neuroimaging; Psychology; Cerebral blood flow; Disease; Dopamine; Medicine; Psychiatry; Internal medicine","score_opus":0.01757569811285168,"score_gpt":0.25381849053028155,"score_spread":0.23624279241742988,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392810755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950965,0.0013388902,0.00032386696,0.000762126,0.0005821951,0.0009212275,0.0008760158,0.000095077456,0.0000040803525],"genre_scores_gemma":[0.9951434,0.00070015894,0.0034357144,0.0002823897,0.00015665394,0.00019969478,2.3912875e-7,0.00007599384,0.0000057624593],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977402,0.0002786995,0.00057095924,0.00093143736,0.00021264757,0.00026604388],"domain_scores_gemma":[0.99861765,0.0006004976,0.00019718388,0.00040438827,0.00005942698,0.00012085194],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047377613,0.00031233596,0.00044477638,0.00018330848,0.00009635201,0.0001866716,0.00029431836,0.00026839282,0.000013580785],"category_scores_gemma":[0.000705867,0.00025194988,0.00015038037,0.0002708957,0.00060525903,0.000058194422,0.00020550562,0.0009210148,0.000002495679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001147042,0.00041778994,0.0020441916,0.0005930557,0.00013697552,0.000012947333,0.00006709925,0.0001312382,0.9685181,0.026432104,0.00045567568,0.000043807864],"study_design_scores_gemma":[0.023874493,0.0004144401,0.26825076,0.0010522417,0.0007016418,1.788578e-7,0.000009061653,0.020397238,0.6777577,0.004405558,0.0013720607,0.0017646535],"about_ca_topic_score_codex":0.000027283131,"about_ca_topic_score_gemma":0.0000135395485,"teacher_disagreement_score":0.2907604,"about_ca_system_score_codex":0.000010753177,"about_ca_system_score_gemma":0.00013912802,"threshold_uncertainty_score":0.99999326},"labels":[],"label_agreement":null},{"id":"W4393002529","doi":"10.1016/j.bbih.2024.100756","title":"Association between cytokines and suicidality in patients with psychosis: A multicentre longitudinal analysis","year":2024,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Norges Forskningsråd; Helse Vest","keywords":"Positive and Negative Syndrome Scale; Schizophrenia (object-oriented programming); Psychosis; Psychiatry; Depression (economics); Major depressive disorder; Medicine; Clinical psychology; Antipsychotic; Clinical Global Impression; Internal medicine; Psychology; Logistic regression; Mood","score_opus":0.0329772647180242,"score_gpt":0.32555665770711173,"score_spread":0.29257939298908753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393002529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99591756,0.00015707938,0.000042615968,0.002805947,0.00008630261,0.0006392166,0.00019042887,0.00013102058,0.000029835051],"genre_scores_gemma":[0.9990984,0.000046237816,0.00007308762,0.0005002456,0.000021727737,0.000042623327,0.00008571288,0.000022525317,0.000109436056],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99748844,0.0006215928,0.0004107537,0.0005257966,0.0004556373,0.0004977841],"domain_scores_gemma":[0.9987243,0.0005785033,0.00016558221,0.000330791,0.000044267847,0.00015657193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006858078,0.00021804553,0.00039164335,0.00044930476,0.00025733467,0.00016500292,0.00019921917,0.00010394613,0.000045644316],"category_scores_gemma":[0.00028953986,0.00019465714,0.00008965273,0.0018331918,0.00007977439,0.0003002926,0.000066433684,0.0004594151,0.0000106788675],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041229665,0.00039786025,0.9898814,0.0000658434,0.00004868784,0.0000042449246,0.0010210975,0.000002830242,0.0001077221,0.000025458978,0.00015454652,0.008249067],"study_design_scores_gemma":[0.0010675513,0.00017461348,0.99775976,0.000067637324,0.00014827085,4.5815358e-7,0.00016913463,0.000043929227,0.00013061627,0.000018524077,0.00022374828,0.00019573333],"about_ca_topic_score_codex":0.0034492172,"about_ca_topic_score_gemma":0.0038649503,"teacher_disagreement_score":0.0080533335,"about_ca_system_score_codex":0.00034281795,"about_ca_system_score_gemma":0.000096651245,"threshold_uncertainty_score":0.7937888},"labels":[],"label_agreement":null},{"id":"W4393007231","doi":"10.1111/jcmm.18160","title":"ApoE4 dysregulation incites depressive symptoms and mitochondrial impairments in mice","year":2024,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Sanming Project of Medicine in Shenzhen; National Natural Science Foundation of China","keywords":"Mitophagy; PINK1; Parkin; Neuroinflammation; Autophagy; Endocrinology; Internal medicine; ATG5; Mitochondrion; Biology; Medicine; Cell biology; Inflammation; Apoptosis; Biochemistry","score_opus":0.007301305924489988,"score_gpt":0.24736723010379488,"score_spread":0.2400659241793049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393007231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832267,0.011167999,0.003773071,0.0010176565,0.00044833557,0.00012076157,0.0000011091254,0.000009390636,0.00023497178],"genre_scores_gemma":[0.99888057,0.00035149007,0.00007468934,0.00045085725,0.00017183945,0.0000013630182,0.0000011688254,0.000012408754,0.00005559181],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898505,0.000093523995,0.0003036532,0.00018307561,0.00029515318,0.00013955437],"domain_scores_gemma":[0.99958616,0.00012381497,0.00009621693,0.00006173838,0.000025714544,0.00010635334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015868184,0.00011425408,0.00019936766,0.00027137887,0.0000309637,0.00003631192,0.00008214796,0.000057696252,0.000019178631],"category_scores_gemma":[0.0002662921,0.000082966406,0.000040765382,0.00020116624,0.00013803809,0.0001523908,0.00003184481,0.00018872073,9.760497e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052958225,0.000024419223,0.0001571038,0.000053591666,0.000012517569,0.0012685175,0.000629609,0.000011772871,0.992148,0.00034167254,0.00013989516,0.0051599713],"study_design_scores_gemma":[0.005251839,0.0009925229,0.0038437766,0.0010955645,0.00010593008,0.00162462,0.00029420995,0.0029105446,0.9737719,0.005906457,0.003938552,0.00026406063],"about_ca_topic_score_codex":0.000008164891,"about_ca_topic_score_gemma":0.0000014565305,"teacher_disagreement_score":0.018376049,"about_ca_system_score_codex":0.000017933658,"about_ca_system_score_gemma":0.000033901146,"threshold_uncertainty_score":0.3383272},"labels":[],"label_agreement":null},{"id":"W4393052811","doi":"10.3389/fpsyt.2024.1349568","title":"Editorial: Further findings in the role of inflammation in the etiology and treatment of schizophrenia","year":2024,"lang":"en","type":"editorial","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Etiology; Schizophrenia (object-oriented programming); Inflammation; Medicine; Psychiatry; Psychology; Immunology","score_opus":0.005352296177142663,"score_gpt":0.2410099124580091,"score_spread":0.23565761628086643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393052811","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07871767,0.0024325126,0.0000024996123,0.0006722798,0.91720027,0.0004949627,0.00006439621,0.000009278608,0.00040611782],"genre_scores_gemma":[0.056837484,0.0018276676,0.00030639922,0.000042501608,0.9407207,0.00015168163,0.00003634283,0.00003962291,0.00003761815],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980487,0.00042165065,0.00048206677,0.00039527618,0.00043169828,0.00022059717],"domain_scores_gemma":[0.9990012,0.00047728233,0.00017290656,0.00031966588,0.000014873081,0.000014075545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046834946,0.00023071624,0.00038638007,0.00043528725,0.00002602654,0.00003163685,0.00048985454,0.0005479734,0.0000040858763],"category_scores_gemma":[0.0003094521,0.00014297996,0.00008778633,0.0005400152,0.00022190594,0.00006689928,0.000031035735,0.0005439739,0.000002269281],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033550884,0.00015799295,0.0028423748,0.00007912628,0.00000998938,0.000001816235,0.0063207992,0.000006686389,0.0003714232,0.00062656123,0.98648655,0.0027611584],"study_design_scores_gemma":[0.0030200596,0.00051815395,0.0022388005,0.00026496066,0.000035473153,0.0000014934295,0.0062833335,0.00006853013,0.00036998861,0.05032902,0.93659836,0.00027182026],"about_ca_topic_score_codex":0.0001241604,"about_ca_topic_score_gemma":0.0005564719,"teacher_disagreement_score":0.049888194,"about_ca_system_score_codex":0.000059341128,"about_ca_system_score_gemma":0.00021186438,"threshold_uncertainty_score":0.5830554},"labels":[],"label_agreement":null},{"id":"W4393056841","doi":"","title":"Variants in the Upstream Region of the Insulin Receptor Substrate-1 Gene Is Associated with Major Depressive Disorder in the Han Chinese Population","year":2020,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Gene; Upstream (networking); Genetics; Insulin receptor; Major depressive disorder; Population; Biology; Insulin; Medicine; Endocrinology; Insulin resistance; Computer science; Environmental health","score_opus":0.13400447695076206,"score_gpt":0.4350227691823244,"score_spread":0.30101829223156235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393056841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945192,0.0009831984,0.000022324346,0.0028312786,0.00011445078,0.00094532926,0.00004815536,0.000012619807,0.0005234884],"genre_scores_gemma":[0.9968208,0.00075487973,0.000008951033,0.0022599902,0.000046248362,0.000045376186,0.000009812933,0.000030425526,0.00002351184],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9963912,0.001381251,0.0006704554,0.0004372412,0.00081250013,0.00030735013],"domain_scores_gemma":[0.99772,0.00069652137,0.00096827035,0.00047937894,0.00006891284,0.00006691417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007378015,0.00027892218,0.00045511624,0.00020776034,0.00025242698,0.00046157805,0.0034018727,0.00010540446,0.0003891457],"category_scores_gemma":[0.0016380316,0.00013765617,0.00012493308,0.0028731215,0.00018228038,0.0010184537,0.0002763558,0.00054590544,0.0000027293281],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039678882,0.0005054486,0.9506252,0.000022889317,0.000030632476,0.000042467273,0.004209881,0.00042483056,0.040596936,0.000041289022,0.0017602562,0.0013434011],"study_design_scores_gemma":[0.0013354876,0.0000209918,0.98039556,0.00017029453,0.000019657617,0.000011972201,0.00042269955,0.00024595135,0.015336118,0.0017844291,0.000065997025,0.00019085644],"about_ca_topic_score_codex":0.0013997298,"about_ca_topic_score_gemma":0.00093514234,"teacher_disagreement_score":0.029770365,"about_ca_system_score_codex":0.000039726936,"about_ca_system_score_gemma":0.00008354028,"threshold_uncertainty_score":0.6321583},"labels":[],"label_agreement":null},{"id":"W4393070997","doi":"10.1016/j.bbih.2024.100761","title":"LPS-induced inflammation reduces GABAergic interneuron markers and brain-derived neurotrophic factor in mouse prefrontal cortex and hippocampus","year":2024,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; University of Toronto","funders":"Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation; Centre for Addiction and Mental Health","keywords":"Interneuron; Prefrontal cortex; GABAergic; Neuroscience; Hippocampus; Brain-derived neurotrophic factor; Neurotrophic factors; Inflammation; Biology; Psychology; Medicine; Internal medicine; Cognition; Immunology; Inhibitory postsynaptic potential; Receptor","score_opus":0.036189908182960716,"score_gpt":0.30695120382831,"score_spread":0.2707612956453493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393070997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931171,0.00044014087,0.000006357276,0.004290198,0.00043427234,0.0012842858,0.00006487642,0.0002967246,0.00006602185],"genre_scores_gemma":[0.9974666,0.0004010859,0.0000348753,0.0016279856,0.00004171737,0.00008862832,0.00002424213,0.000072644085,0.00024217027],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99662036,0.0010354974,0.0005953075,0.000797986,0.00032502747,0.00062584423],"domain_scores_gemma":[0.9985178,0.0006148175,0.00016730129,0.0003977166,0.00002008719,0.00028224158],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041098116,0.00038971778,0.00038517127,0.0004473641,0.00030222352,0.0003053738,0.00032028442,0.0001558529,0.000051467134],"category_scores_gemma":[0.0005540348,0.00039892123,0.000074558695,0.00041733257,0.00028044023,0.00059906836,0.0002466318,0.0008798398,0.000015600832],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001139317,0.00012397303,0.0008885606,0.00017684234,0.000003555861,0.0000763852,0.003057727,7.61566e-7,0.9327096,0.00007287098,0.00009083333,0.062685],"study_design_scores_gemma":[0.0017667419,0.0011724132,0.9054774,0.00030197142,0.000010586476,0.00020591199,0.0011313969,0.0005677523,0.088232726,0.00015874491,0.00035550338,0.0006188453],"about_ca_topic_score_codex":0.0008933433,"about_ca_topic_score_gemma":0.0005212192,"teacher_disagreement_score":0.9045888,"about_ca_system_score_codex":0.00018503107,"about_ca_system_score_gemma":0.0002705952,"threshold_uncertainty_score":0.9998463},"labels":[],"label_agreement":null},{"id":"W4393115557","doi":"10.1007/s12325-024-02826-9","title":"Assessing the Effects of Metabolic Disruption, Body Mass Index and Inflammation on Depressive Symptoms in Post-COVID-19 Condition: A Randomized Controlled Trial on Vortioxetine","year":2024,"lang":"en","type":"article","venue":"Advances in Therapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Toronto; Brain and Cognition Discovery Foundation; University of Ottawa","funders":"","keywords":"Vortioxetine; Medicine; Placebo; Internal medicine; Clinical endpoint; Randomized controlled trial; Body mass index; Mood; Physical therapy; Major depressive disorder; Psychiatry; Pathology","score_opus":0.008732925826616594,"score_gpt":0.3325133837605865,"score_spread":0.32378045793396987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393115557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98472756,0.009080174,0.0008499657,0.00083944225,0.00062595174,0.0035548564,0.0000033824122,0.00004483159,0.00027385482],"genre_scores_gemma":[0.9921695,0.0058062426,0.000008328772,0.0009841127,0.000095647425,0.0008961334,0.0000037661898,0.000013724984,0.000022571487],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9975613,0.0011711187,0.00047288366,0.00034026976,0.00028910983,0.00016532028],"domain_scores_gemma":[0.99124473,0.008310815,0.00022561206,0.00016070348,0.000020496569,0.000037662936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006654177,0.00017980712,0.0005912235,0.00027895797,0.00007974226,0.00011455372,0.00013439721,0.000062645995,0.000022713566],"category_scores_gemma":[0.0036994237,0.00010580747,0.00012240857,0.00037867186,0.0002632239,0.0005255207,0.00001120052,0.00019970888,0.0000021790997],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.77379155,0.00024240014,0.00032916182,0.00015006661,0.00007421009,0.00005217034,0.0017211796,0.0030731575,0.13648567,0.03445274,0.0000034654438,0.04962424],"study_design_scores_gemma":[0.92619395,0.0003724126,0.0015055123,0.00021205447,0.000020213856,0.00000304887,0.000108490975,0.0031135033,0.04896419,0.018745989,0.0005894235,0.00017122958],"about_ca_topic_score_codex":0.000009001898,"about_ca_topic_score_gemma":0.000009310646,"teacher_disagreement_score":0.15240239,"about_ca_system_score_codex":0.000026516567,"about_ca_system_score_gemma":0.000071427196,"threshold_uncertainty_score":0.4428823},"labels":[],"label_agreement":null},{"id":"W4393237093","doi":"10.1016/j.pnpbp.2024.110998","title":"Time-dependent antidepressant-like effects of reelin and ketamine in the repeated-corticosterone model of chronic stress","year":2024,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Ketamine; Reelin; Antidepressant; NMDA receptor; Corticosterone; Pharmacology; Medicine; Antagonist; Endocrinology; Internal medicine; Hippocampus; Psychology; Anesthesia; Receptor; Hormone","score_opus":0.018184350941332975,"score_gpt":0.2950000451949652,"score_spread":0.2768156942536322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393237093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97772855,0.01937505,0.00001741307,0.0011670376,0.0008024384,0.0007431967,0.000028775867,0.00005068961,0.00008683145],"genre_scores_gemma":[0.9944916,0.0043473123,0.000056510085,0.0009304485,0.00005772466,0.00008430681,0.0000025739628,0.0000143462385,0.000015221138],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976735,0.0005307793,0.0005319394,0.00073885516,0.00016666563,0.00035822694],"domain_scores_gemma":[0.9987119,0.0008676787,0.00013391927,0.0002170413,0.0000125729,0.00005688552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032426638,0.00024319481,0.0003738555,0.00019653642,0.000049367125,0.000022777333,0.0003732544,0.00020479051,0.00001960128],"category_scores_gemma":[0.00009584427,0.00015323068,0.0000629947,0.00038681173,0.0009873409,0.00008964599,0.00014495714,0.0005480692,0.0000025655504],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032732757,0.00411145,0.59805787,0.0026663,0.00006566863,0.00046624805,0.0006954119,0.00038429574,0.33204296,0.0015509698,0.0007152029,0.05597036],"study_design_scores_gemma":[0.013708158,0.0053235358,0.8571134,0.0010755018,0.00013257988,0.00025470022,0.00015353598,0.08153545,0.031708788,0.0077821473,0.00023006035,0.0009821418],"about_ca_topic_score_codex":0.000002151833,"about_ca_topic_score_gemma":0.00000774424,"teacher_disagreement_score":0.3003342,"about_ca_system_score_codex":0.000008016163,"about_ca_system_score_gemma":0.0000361702,"threshold_uncertainty_score":0.6248566},"labels":[],"label_agreement":null},{"id":"W4393313246","doi":"10.1016/j.bbih.2024.100768","title":"Cord serum cytokines at birth and children's trajectories of mood dysregulation symptoms from 3 to 8 years: The EDEN birth cohort","year":2024,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Research Unit on Children's Psychosocial Maladjustment","funders":"CHIST-ERA; Fondation Pierre Deniker pour la Recherche et la Prévention en Santé Mentale; Fondation de France; Institut National de la Santé et de la Recherche Médicale; Université Paris-Sud; Agence Nationale de la Recherche","keywords":"Mood; Immune dysregulation; Pregnancy; Cohort; Medicine; Odds ratio; Mood disorders; Population; Cohort study; Psychology; Psychiatry; Pediatrics; Clinical psychology; Internal medicine; Anxiety; Disease","score_opus":0.019721560223941857,"score_gpt":0.290477192612019,"score_spread":0.27075563238807715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393313246","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938141,0.00045628546,0.00002148944,0.0030197415,0.00042668515,0.0011377562,0.00084619585,0.0002136796,0.00006407442],"genre_scores_gemma":[0.9979558,0.00014207684,0.000055511635,0.0010355803,0.00009041729,0.00006050628,0.000056475354,0.00004944114,0.00055421464],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99785835,0.00041986894,0.00041205258,0.00048627701,0.00041589965,0.0004075419],"domain_scores_gemma":[0.9985571,0.0005217667,0.00012809015,0.00059851777,0.000029015824,0.00016551401],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040510087,0.00024546887,0.00032489168,0.00017965415,0.0003517121,0.00013344947,0.00040806146,0.00009341661,0.00017253219],"category_scores_gemma":[0.00018436094,0.00020097052,0.000088646106,0.0006912943,0.00029755154,0.00019708926,0.00023380424,0.00030257355,0.000026879236],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004130448,0.0006389363,0.6925098,0.000249633,0.000074875374,0.000015354362,0.018636294,0.000027584338,0.1675431,0.0024300073,0.0035776356,0.11388379],"study_design_scores_gemma":[0.00038628848,0.00034516578,0.98863024,0.00008768297,0.000017501936,0.000021370897,0.00033643725,0.000024958457,0.008069352,0.00011714088,0.0017629599,0.00020087794],"about_ca_topic_score_codex":0.0025870635,"about_ca_topic_score_gemma":0.0012392628,"teacher_disagreement_score":0.29612052,"about_ca_system_score_codex":0.00011391204,"about_ca_system_score_gemma":0.0001733052,"threshold_uncertainty_score":0.819534},"labels":[],"label_agreement":null},{"id":"W4393321499","doi":"10.1016/j.bbi.2024.03.049","title":"Plasma complement and coagulation proteins as prognostic factors of negative symptoms: An analysis of the NAPLS 2 and 3 studies","year":2024,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"National Institute of Mental Health; European Regional Development Fund; Science Foundation Ireland; Wellcome Trust","keywords":"Internal medicine; Schizophrenia (object-oriented programming); Schizoaffective disorder; Prodrome; Clinical psychology; Medicine; Psychosis; Psychology; Psychiatry","score_opus":0.062383306864261794,"score_gpt":0.3418207343612772,"score_spread":0.2794374274970154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393321499","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988754,0.0002376859,0.000007039056,0.00009462551,0.000037169524,0.000602456,0.00010464141,0.00001962276,0.000021371874],"genre_scores_gemma":[0.9998289,0.000050637613,0.000017631495,0.000027282336,0.0000025775932,0.0000287519,0.0000067013243,0.0000063899784,0.000031149284],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99907845,0.00024775215,0.00020416375,0.00020386005,0.0001622255,0.00010357136],"domain_scores_gemma":[0.99906546,0.00062011374,0.00008204943,0.00015848874,0.000037877457,0.00003603068],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015982836,0.000117921045,0.00022778622,0.0001424614,0.00018869115,0.00004069107,0.00009266621,0.000032059073,0.000014434542],"category_scores_gemma":[0.00045238106,0.00007803425,0.000048270245,0.00045943246,0.0005697978,0.00014896163,0.00013118617,0.00009936238,1.0925164e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006216245,0.00043844568,0.48081002,0.00025817298,0.0002873514,0.0000023770378,0.03296312,0.000013582207,0.46737155,0.0044658533,0.000015110992,0.013312244],"study_design_scores_gemma":[0.00025908588,0.0002766187,0.9094918,0.000056539146,0.00030339492,0.000002187299,0.0056674564,0.0005198208,0.08311197,0.00021159965,0.000013608679,0.00008593569],"about_ca_topic_score_codex":0.00027682228,"about_ca_topic_score_gemma":0.00019974714,"teacher_disagreement_score":0.42868176,"about_ca_system_score_codex":0.000011592497,"about_ca_system_score_gemma":0.000021558615,"threshold_uncertainty_score":0.31821445},"labels":[],"label_agreement":null},{"id":"W4393861064","doi":"10.1186/s13293-024-00605-3","title":"Correction: Nrf2 activation rescues stress-induced depression-like behaviour and inflammatory responses in male but not female rats","year":2024,"lang":"en","type":"erratum","venue":"Biology of Sex Differences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Depression (economics); Human physiology; Medicine; Stress (linguistics); Physiology; Endocrinology; Internal medicine; Biology; Psychology","score_opus":0.042608800334969194,"score_gpt":0.29293029520455355,"score_spread":0.2503214948695843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393861064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98391366,0.00086457666,0.0000014621829,0.00012947101,0.01229126,0.00032249358,0.0001422568,0.000087377855,0.002247451],"genre_scores_gemma":[0.945269,0.0010394854,0.00000827843,0.000099242054,0.00030724422,0.00006665788,0.000058171743,0.000026960593,0.053124957],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975402,0.000494543,0.00048120873,0.00091539434,0.0002328404,0.00033580832],"domain_scores_gemma":[0.99846435,0.00081812637,0.00029879337,0.00030829568,0.000039480517,0.00007096583],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017219601,0.00038147878,0.00055697333,0.00051518687,0.0001350082,0.00006153105,0.0003864194,0.0008329214,0.00009892653],"category_scores_gemma":[0.00066175195,0.00030900203,0.000073454255,0.00023182892,0.0005180153,0.00013161986,0.00022296837,0.0008822135,0.0000119654205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000749231,0.00029304877,0.25193644,0.00055668835,0.000042427266,0.00008580705,0.001977274,8.761209e-7,0.6801953,0.00011700084,0.04995389,0.014092052],"study_design_scores_gemma":[0.00041183716,0.00034988043,0.48769975,0.0012094586,0.000025195408,0.000026177237,0.0018428541,0.00006267346,0.5052171,0.0003324841,0.0022701703,0.000552416],"about_ca_topic_score_codex":0.0002564482,"about_ca_topic_score_gemma":0.00036099783,"teacher_disagreement_score":0.23576331,"about_ca_system_score_codex":0.000035932342,"about_ca_system_score_gemma":0.00025506786,"threshold_uncertainty_score":0.9999362},"labels":[],"label_agreement":null},{"id":"W4393927028","doi":"10.1159/000538060","title":"The Relationship between Neurobiological Function and Inflammation in Depressed Children and Adolescents: A Scoping Review","year":2024,"lang":"en","type":"review","venue":"Neuropsychobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Baycrest Hospital; Hospital for Sick Children; Public Health Ontario; University of Toronto; SickKids Foundation","funders":"","keywords":"Depression (economics); Anterior cingulate cortex; Psychology; Inflammation; Brain Structure and Function; Clinical psychology; Neuroscience; Medicine; Neuroimaging; Internal medicine; Cognition","score_opus":0.08141602579067135,"score_gpt":0.3595867529483387,"score_spread":0.27817072715766733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393927028","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003954846,0.9931978,0.0000045408615,0.00030667344,0.00034613902,0.0020307044,0.000020451262,0.00008707291,0.000051749437],"genre_scores_gemma":[0.009437136,0.9897696,0.000001557056,0.000439345,0.00013871328,0.000121803576,0.00003838467,0.000033565622,0.00001992971],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9965381,0.0015116408,0.00068478804,0.0008880054,0.00007601308,0.00030144633],"domain_scores_gemma":[0.99754316,0.0018283521,0.00024994105,0.000309906,0.000008826549,0.00005981611],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032373884,0.00034995502,0.0007665194,0.0001603103,0.00017163316,0.000084398576,0.00026290424,0.00028543823,0.0000032109174],"category_scores_gemma":[0.0018852452,0.00021219798,0.00011345107,0.0005021854,0.00028841465,0.000073983,0.00017219024,0.00088136387,0.000054140735],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030034875,0.00002768924,0.011648784,0.04778168,0.000017019993,0.000012527047,0.000013835353,1.5221113e-7,0.00006083067,0.0016080046,0.00043031358,0.93836915],"study_design_scores_gemma":[0.001189574,0.00054697244,0.36132672,0.4832381,0.0008458324,0.00056169054,0.0000029839618,0.0000034090663,0.0000031973534,0.0037610277,0.14727531,0.0012451827],"about_ca_topic_score_codex":0.000001600373,"about_ca_topic_score_gemma":0.000008773555,"teacher_disagreement_score":0.93712395,"about_ca_system_score_codex":0.000014029999,"about_ca_system_score_gemma":0.000045067387,"threshold_uncertainty_score":0.86531824},"labels":[],"label_agreement":null},{"id":"W4394014558","doi":"10.1021/acs.jafc.4c01052","title":"Bioavailability and Metabolism of Bioactive Peptide IRW with Angiotensin-Converting Enzyme 2 (ACE2) Upregulatory Activity in Spontaneously Hypertensive Rats","year":2024,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Metabolite; Bioavailability; Kynurenine; Blood pressure; Pharmacology; Chemistry; Oral administration; Pharmacokinetics; Active metabolite; Kynurenine pathway; Metabolism; Angiotensin II; Renin–angiotensin system; Angiotensin-converting enzyme; Tryptophan; Endocrinology; Biochemistry; Medicine; Amino acid","score_opus":0.010311017014555487,"score_gpt":0.19896625403582457,"score_spread":0.18865523702126907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394014558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99678326,0.0023797702,0.0000014099077,0.0005301704,0.00006126667,0.00007737367,0.000014213081,0.000013345337,0.00013918159],"genre_scores_gemma":[0.9995761,0.00015047281,0.000058970967,0.000047423953,0.00008182496,8.1234214e-7,4.339356e-7,0.0000068976865,0.00007707395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990353,0.00004216038,0.0002653676,0.00026844535,0.00020916361,0.00017954684],"domain_scores_gemma":[0.9993314,0.00018242453,0.00019919893,0.000073937954,0.0001068824,0.00010614234],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010500145,0.0001817246,0.00035572637,0.000039669747,0.000046215482,0.000046810917,0.000088767425,0.00008976484,0.000008510871],"category_scores_gemma":[0.0001221634,0.000100579084,0.000090687055,0.00023823179,0.00025082467,0.00030034894,0.000046788577,0.00031946704,3.177242e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012916335,0.000058857528,0.00020174711,0.00012335816,0.00004157443,0.00009594374,0.0005584476,0.00000634136,0.99771756,0.000009005156,0.00006580968,0.0009922066],"study_design_scores_gemma":[0.00042238735,0.00013125528,0.09608494,0.00017681567,0.000036989637,0.002404958,0.0011651934,0.000023935865,0.89928,0.000048025257,0.00007853857,0.00014693454],"about_ca_topic_score_codex":0.00001097338,"about_ca_topic_score_gemma":0.000010415705,"teacher_disagreement_score":0.09843751,"about_ca_system_score_codex":0.00002819854,"about_ca_system_score_gemma":0.000050133764,"threshold_uncertainty_score":0.4101496},"labels":[],"label_agreement":null},{"id":"W4394017106","doi":"10.1016/j.clinsp.2024.100347","title":"Could immunotherapy be a hope for addiction treatment?","year":2024,"lang":"en","type":"editorial","venue":"Clinics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Addiction; Immunotherapy; Medicine; Psychology; Psychotherapist; Psychiatry; Immunology; Immune system","score_opus":0.045056514184042926,"score_gpt":0.3630301648607937,"score_spread":0.31797365067675076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394017106","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017503575,0.0018810251,0.00008885496,0.00042818836,0.99199104,0.000772942,0.0027081592,0.0003020415,0.0016527047],"genre_scores_gemma":[0.00016935148,0.0132797295,0.000114687864,0.0010892865,0.9390523,0.00041326124,0.00064934936,0.00020275883,0.045029268],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980943,0.00006338705,0.00040820177,0.00076435256,0.00035395595,0.0003157595],"domain_scores_gemma":[0.99631757,0.0029297972,0.00018067188,0.00045296486,0.00005604487,0.00006294443],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014859857,0.00033987712,0.00039977557,0.00011099729,0.00014148068,0.00016815464,0.00033608347,0.00090341497,0.000112153684],"category_scores_gemma":[0.0014596928,0.00028802743,0.00044306577,0.00016843158,0.00011755186,0.00007208688,0.00003443043,0.0004899538,0.00022521023],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021486069,0.00014224526,2.1019797e-7,0.000040676565,0.000042526553,0.000007246831,0.00011336575,0.000001705532,0.00050991756,0.000119615215,0.96931624,0.029491385],"study_design_scores_gemma":[0.0016251011,0.0009509706,6.063571e-7,0.000060099414,0.000056821566,5.41157e-7,0.00001751554,0.00014052479,0.0011626324,0.0010642548,0.99464357,0.000277352],"about_ca_topic_score_codex":0.0000072176526,"about_ca_topic_score_gemma":0.0000169227,"teacher_disagreement_score":0.05293874,"about_ca_system_score_codex":0.00013872777,"about_ca_system_score_gemma":0.00035016346,"threshold_uncertainty_score":0.9999572},"labels":[],"label_agreement":null},{"id":"W4394233569","doi":"10.6084/m9.figshare.22697040","title":"Additional file 1 of Identification of mitophagy-related biomarkers and immune infiltration in major depressive disorder","year":2023,"lang":"en","type":"dataset","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Defence Research and Development Canada","funders":"","keywords":"Mitophagy; Immune system; Infiltration (HVAC); Identification (biology); Immune Dysfunction; Major depressive disorder; Computational biology; Psychology; Biology; Immunology; Neuroscience; Genetics; Materials science; Ecology; Autophagy","score_opus":0.01865328220426183,"score_gpt":0.25037998960012015,"score_spread":0.23172670739585832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394233569","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000032519634,0.000099707715,1.6783963e-8,0.000012093912,0.000045600467,0.0003328739,0.9994118,0.00002142895,0.00004394776],"genre_scores_gemma":[0.00010692689,0.000016828713,0.0000044875537,0.000014927931,0.000012912686,0.00065227615,0.99900025,0.000016597434,0.00017479357],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998625,0.000086032145,0.00052369176,0.00036421572,0.00026010358,0.00014098418],"domain_scores_gemma":[0.99718094,0.00181864,0.00063538307,0.00027909683,0.000056542707,0.000029399445],"candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000023922892,0.00016552243,0.00022718603,0.00032521636,0.000045209876,0.000023473081,0.00027683467,0.00023353167,0.8557828],"category_scores_gemma":[0.0102857435,0.0001751489,0.00007229058,0.0006056571,0.000050291444,0.0001623875,0.00011413118,0.00017435482,0.001362935],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001391054,0.000060024537,3.1524294e-7,0.00036694828,0.000012424763,0.0000060549064,0.000011582537,0.0000039938063,0.0014764692,4.783303e-7,0.99767417,0.00037362712],"study_design_scores_gemma":[0.0007118199,0.00004252699,0.014048937,0.0039564027,0.000010077518,0.000006107589,0.00005271725,0.0001059617,0.011420809,0.00014001012,0.9691888,0.0003158199],"about_ca_topic_score_codex":0.000048739323,"about_ca_topic_score_gemma":0.00010270066,"teacher_disagreement_score":0.8544198,"about_ca_system_score_codex":0.000014427423,"about_ca_system_score_gemma":0.000086453954,"threshold_uncertainty_score":0.9994146},"labels":[],"label_agreement":null},{"id":"W4394542359","doi":"10.6084/m9.figshare.24037842","title":"The pharmacological actions of Danzhi-xiaoyao-San on depression involve lysophosphatidic acid and microbiota-gut-brain axis: novel insights from a systems pharmacology analysis of a double-blind, randomized, placebo-controlled clinical trial","year":2023,"lang":"en","type":"dataset","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Gut–brain axis; Lysophosphatidic acid; Pharmacology; Medicine; Placebo; Neuroscience; Clinical trial; Gut flora; Psychology; Internal medicine; Receptor; Alternative medicine","score_opus":0.150231792287239,"score_gpt":0.38872438909141577,"score_spread":0.23849259680417675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394542359","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012428008,0.0015663806,0.000001790047,0.00013040502,0.0018037512,0.0074911313,0.97644323,0.000083533734,0.000051769053],"genre_scores_gemma":[0.024775557,0.000818722,0.0000046187415,0.0005818069,0.0005019816,0.0041074185,0.96903366,0.000049171922,0.00012707188],"study_design_codex":"not_applicable","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9924817,0.0025337383,0.002364734,0.0013923049,0.00071578537,0.00051171024],"domain_scores_gemma":[0.96750015,0.028691407,0.0026361956,0.0007466086,0.00017087488,0.0002547652],"candidate_categories":["metaresearch","metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008320301,0.0007107863,0.0034994334,0.0008224629,0.000407586,0.00016123248,0.0013521428,0.0009981506,0.0041761366],"category_scores_gemma":[0.009153538,0.00044638096,0.0015201095,0.0015865037,0.00038563923,0.00012521166,0.0005873209,0.0012308041,0.00021619858],"study_design_candidate":"randomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.44939023,0.00054093933,1.3542267e-7,0.000079403166,0.0019648643,0.000018605548,0.00002126569,0.0000624385,0.009223468,0.00000577451,0.5386645,0.00002836279],"study_design_scores_gemma":[0.86155236,0.00039099716,0.000010915185,0.0005967619,0.0033531778,0.0000024483575,0.000090853326,0.0015827878,0.006515437,0.000006008729,0.12545516,0.00044309805],"about_ca_topic_score_codex":0.00019439349,"about_ca_topic_score_gemma":0.00014354577,"teacher_disagreement_score":0.41320935,"about_ca_system_score_codex":0.00008267053,"about_ca_system_score_gemma":0.00033019387,"threshold_uncertainty_score":0.9997988},"labels":[],"label_agreement":null},{"id":"W4394611926","doi":"10.1152/ajpgi.00306.2023","title":"Oral tryptophan activates duodenal aryl hydrocarbon receptor in healthy subjects: a crossover randomized controlled trial","year":2024,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"Institut National de la Santé et de la Recherche Médicale; Canadian Institutes of Health Research; Joint Programming Initiative A healthy diet for a healthy life; Clinical Trials Fund, Canadian Institutes of Health Research","keywords":"Aryl hydrocarbon receptor; Tryptophan; Kynurenine; Crossover study; Kynurenine pathway; Placebo; Internal medicine; Metabolite; Endocrinology; Pharmacology; Serotonin; Chemistry; Biology; Medicine; Receptor; Biochemistry; Amino acid; Pathology","score_opus":0.011861265702519826,"score_gpt":0.2621683134357205,"score_spread":0.25030704773320067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394611926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997066,0.0005819947,0.00005789416,0.0006427482,0.0006039334,0.0008782014,0.000009842133,0.000054852284,0.00010452555],"genre_scores_gemma":[0.99730194,0.00043972654,0.0005395949,0.0009784319,0.0005902235,0.00006807896,0.0000035620283,0.00003644533,0.000042014046],"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99566156,0.0014794146,0.0011610156,0.0007045027,0.00026633943,0.0007271669],"domain_scores_gemma":[0.99452764,0.00412781,0.0008398794,0.00018480043,0.00008353448,0.00023631904],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007119738,0.00047079808,0.0025729716,0.0004667013,0.000119397526,0.00006505352,0.00038506213,0.000074823205,0.00014131673],"category_scores_gemma":[0.0014734047,0.00031829995,0.00064986193,0.00055200676,0.002339945,0.00031964737,0.000112569534,0.00094550836,0.000020872769],"study_design_candidate":"randomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.49306622,0.0002277271,0.000009042424,0.000027211297,0.00004840876,0.000043619944,0.00019653697,0.000034418914,0.50489104,0.0006300061,0.000064418055,0.0007613674],"study_design_scores_gemma":[0.9506319,0.017239211,0.0028084458,0.00046701473,0.00010395467,0.0013694969,0.00056464435,0.0034554384,0.013969404,0.008663369,0.00014940833,0.0005776736],"about_ca_topic_score_codex":0.0001348788,"about_ca_topic_score_gemma":0.00000765817,"teacher_disagreement_score":0.49092162,"about_ca_system_score_codex":0.00007509131,"about_ca_system_score_gemma":0.00029791496,"threshold_uncertainty_score":0.9999269},"labels":[],"label_agreement":null},{"id":"W4394620314","doi":"10.1111/pcn.13670","title":"Association between serum cytokines and timeframe for conversion from clinical high‐risk to psychosis","year":2024,"lang":"en","type":"article","venue":"Psychiatry and Clinical Neurosciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China","keywords":"Psychosis; Quantile regression; Internal medicine; Medicine; Cytokine; Quantile; Tumor necrosis factor alpha; Vascular endothelial growth factor; Interleukin 6; Correlation; Oncology; Endocrinology; Gastroenterology; VEGF receptors; Psychiatry; Econometrics","score_opus":0.04119151846109001,"score_gpt":0.3624423257831116,"score_spread":0.3212508073220216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394620314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9700912,0.00017960212,0.00050500577,0.01726733,0.0108804675,0.00039059913,0.00044955587,0.0001568601,0.0000793657],"genre_scores_gemma":[0.9902552,0.0022225739,0.001089516,0.0047703553,0.0011592059,0.000015223856,0.000003583471,0.000019014618,0.0004653575],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99686295,0.00039903398,0.00071205443,0.0013252987,0.00033553736,0.0003651295],"domain_scores_gemma":[0.99301773,0.006220245,0.00018191378,0.00021195762,0.000024115569,0.0003440574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012234568,0.0002049522,0.0003669463,0.00008964676,0.00038517072,0.0003841563,0.0003324933,0.00023683663,0.000037733378],"category_scores_gemma":[0.0032226809,0.00016430566,0.00019246679,0.0004573813,0.00035518824,0.0003074894,0.00012343988,0.00041632814,0.000055666595],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008211946,0.00019867766,0.96880895,0.00003015578,0.00002039656,0.0000011763817,0.000023627003,7.991663e-7,0.00041850313,0.0005631584,0.005481628,0.024370793],"study_design_scores_gemma":[0.00095214345,0.0017155039,0.9604979,0.00007110702,0.0001247698,0.0000011556375,0.00007275487,0.0010715376,0.0004714894,0.01093668,0.023767082,0.00031787463],"about_ca_topic_score_codex":0.00004683844,"about_ca_topic_score_gemma":0.00003809632,"teacher_disagreement_score":0.02405292,"about_ca_system_score_codex":0.000008394089,"about_ca_system_score_gemma":0.000054380802,"threshold_uncertainty_score":0.67001903},"labels":[],"label_agreement":null},{"id":"W4394688202","doi":"10.1186/s11556-024-00344-9","title":"Resistance training's impact on blood biomarkers and cognitive function in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial","year":2024,"lang":"en","type":"article","venue":"European Review of Aging and Physical Activity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Lietuvos Mokslo Taryba","keywords":"Montreal Cognitive Assessment; Cognition; Medicine; Randomized controlled trial; Neuropsychology; Cognitive decline; Biomarker; Neuropsychological assessment; Effects of sleep deprivation on cognitive performance; Physical therapy; Psychology; Physical medicine and rehabilitation; Internal medicine; Cognitive impairment; Dementia; Disease; Psychiatry","score_opus":0.009511058581223445,"score_gpt":0.2597191382196209,"score_spread":0.2502080796383975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394688202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899817,0.007024337,0.000030707397,0.00007520182,0.00003322639,0.0022391195,0.000077902725,0.00002395631,0.00051382266],"genre_scores_gemma":[0.99270815,0.0071008937,0.0000046829214,0.000075964876,0.000036552716,0.000040776948,0.0000025697382,0.000018088876,0.00001233639],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99715453,0.0018014116,0.00024549282,0.00045293767,0.00018995383,0.00015568512],"domain_scores_gemma":[0.99617326,0.0033989402,0.00025238152,0.00007578565,0.000030880903,0.00006877708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008831931,0.0002263708,0.0010423108,0.000087249166,0.000051467305,0.000031401953,0.0000374257,0.00001664175,0.0000045662887],"category_scores_gemma":[0.0007308884,0.00013356865,0.00017949552,0.00026251018,0.000406351,0.00012755721,0.000025350555,0.00020781024,6.6428476e-7],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.93386734,0.0010987986,0.000059226637,0.004558405,0.00047032724,0.00003169134,0.002431743,4.1573594e-7,0.00071648345,0.00006939286,0.000011395962,0.056684777],"study_design_scores_gemma":[0.8996449,0.0020254878,0.039386712,0.053809498,0.0011804523,0.0000051697884,0.00018556662,0.00034172283,0.00300811,0.00012574233,0.000001470112,0.0002851818],"about_ca_topic_score_codex":0.000027932248,"about_ca_topic_score_gemma":0.0000028800491,"teacher_disagreement_score":0.056399595,"about_ca_system_score_codex":0.0000047314998,"about_ca_system_score_gemma":0.000027033198,"threshold_uncertainty_score":0.5446772},"labels":[],"label_agreement":null},{"id":"W4394690171","doi":"10.1053/j.gastro.2024.03.041","title":"Microbial Metabolite: A Link Between Psychological Stress and Epithelial Disturbance","year":2024,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Disturbance (geology); Metabolite; Link (geometry); Psychological stress; Chemistry; Psychology; Environmental chemistry; Clinical psychology; Biology; Computer science; Biochemistry","score_opus":0.02195203414958284,"score_gpt":0.28107205588940903,"score_spread":0.2591200217398262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394690171","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918526,0.00021330902,0.0010613381,0.0052065533,0.00082984945,0.0001385815,0.00035217486,0.00016530669,0.00018030145],"genre_scores_gemma":[0.9971175,0.00008870778,0.00019633582,0.0016927571,0.00066884246,0.000014496742,0.000010501079,0.000016608124,0.00019421671],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984731,0.0001737359,0.00019460873,0.00062675506,0.00009367434,0.000438135],"domain_scores_gemma":[0.9995616,0.00012061009,0.000030250922,0.0001806073,0.0000069852977,0.000099929886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000077145145,0.00016632567,0.0002233997,0.00008160505,0.00006744131,0.000079063975,0.00023326115,0.00009357053,0.00006575752],"category_scores_gemma":[0.00007749775,0.0001190331,0.00007557153,0.0001101092,0.000390994,0.00008798451,0.00011537293,0.00028797518,0.00008037624],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011836983,0.00032304684,0.15018994,0.00025817825,0.00010923508,0.0006255696,0.0011300794,0.000009802137,0.7019969,0.0072712656,0.004749293,0.132153],"study_design_scores_gemma":[0.003730808,0.002175112,0.819927,0.00010756398,0.000090526904,0.00044347974,0.000055020337,0.00018172142,0.06867532,0.006013771,0.09805887,0.0005408473],"about_ca_topic_score_codex":0.0000034874483,"about_ca_topic_score_gemma":0.0000057793313,"teacher_disagreement_score":0.66973704,"about_ca_system_score_codex":0.000008805184,"about_ca_system_score_gemma":0.000005889107,"threshold_uncertainty_score":0.4854029},"labels":[],"label_agreement":null},{"id":"W4394707201","doi":"10.1016/j.intimp.2024.111964","title":"NMDAR (2C) deletion in astrocytes relieved LPS-induced neuroinflammation and depression","year":2024,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Neuroinflammation; Astrocyte; Microglia; NMDA receptor; Knockout mouse; Neuroscience; Glutamate receptor; Receptor; Pharmacology; Medicine; Biology; Internal medicine; Central nervous system; Inflammation","score_opus":0.02137221880906237,"score_gpt":0.30795697764006025,"score_spread":0.2865847588309979,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394707201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938576,0.00029362773,0.00006359914,0.0010778707,0.0023546296,0.00020976871,0.000005347454,0.00012865996,0.002008903],"genre_scores_gemma":[0.9987156,0.0002869169,0.0000631476,0.00048925355,0.00011496297,0.000039638497,0.000009203358,0.000017133962,0.00026416066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988974,0.00011894694,0.0002472529,0.00038445136,0.0001736816,0.00017829458],"domain_scores_gemma":[0.9995286,0.00028444035,0.000049812614,0.00007423306,0.00002877753,0.00003416425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012047917,0.0001211003,0.000099715864,0.00028673993,0.0000429893,0.00008771835,0.00020081797,0.00007346481,0.0004873431],"category_scores_gemma":[0.00017893418,0.000118823904,0.00003523565,0.00018147989,0.00004654512,0.00035710086,0.00010252557,0.00025197532,0.0001750807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014206016,0.000037753958,0.00040155172,0.000012876105,0.0000073856218,0.00007056622,0.00014403097,0.00006742522,0.9827706,0.0010418644,0.00021030943,0.015093578],"study_design_scores_gemma":[0.0012033795,0.00006925322,0.021518013,0.000057116835,0.0000048719917,0.00007721225,0.000044046858,0.017316429,0.9516444,0.0007808713,0.007129243,0.00015516003],"about_ca_topic_score_codex":0.000025153413,"about_ca_topic_score_gemma":0.000007329312,"teacher_disagreement_score":0.031126196,"about_ca_system_score_codex":0.00007051905,"about_ca_system_score_gemma":0.00003366189,"threshold_uncertainty_score":0.5336065},"labels":[],"label_agreement":null},{"id":"W4394720683","doi":"10.1152/japplphysiol.00031.2024","title":"Cerebrovascular dysfunction and depressive symptoms in preclinical models: insights from a scoping review","year":2024,"lang":"en","type":"review","venue":"Journal of Applied Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Institute of Health Services and Policy Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Medicine; Depression (economics); CLARITY; Depressive symptoms; Serotonergic; MEDLINE; Executive dysfunction; Psychology; Bioinformatics; Clinical psychology; Neuroscience; Psychiatry; Internal medicine; Cognition; Biology; Serotonin","score_opus":0.07338309376411682,"score_gpt":0.3510816471804292,"score_spread":0.2776985534163124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394720683","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008640676,0.99739754,0.000030368801,0.000016488271,0.00043922337,0.0008698658,0.000007340854,0.000017137898,0.0003579395],"genre_scores_gemma":[0.0010477874,0.9980112,0.000038152917,0.00048157765,0.00030153044,0.00006435634,0.000007883068,0.000043225013,0.0000043430864],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.99720544,0.00035978356,0.0013271066,0.00064602157,0.00023540095,0.0002262718],"domain_scores_gemma":[0.9978378,0.0008054454,0.00093182747,0.00029742968,0.000027154885,0.00010037903],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016161964,0.0003850749,0.002468174,0.0002632328,0.000039429684,0.000033411452,0.00038122406,0.00035847156,0.000027327105],"category_scores_gemma":[0.00016819434,0.00025667183,0.00052093226,0.00036905543,0.0001493684,0.00013078858,0.00019169589,0.0011368893,0.000033379194],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001309044,0.00025438142,1.6022935e-7,0.13209802,0.00043792927,0.00008921237,0.00020033777,0.000105700936,0.0013278669,0.003122131,0.0005595115,0.86167383],"study_design_scores_gemma":[0.0019661663,0.00028266007,0.00001612434,0.8417044,0.0025339024,0.00021756595,0.000018238125,0.00025757443,0.00014874904,0.05922258,0.092645384,0.000986607],"about_ca_topic_score_codex":0.0000026692073,"about_ca_topic_score_gemma":0.0000034318227,"teacher_disagreement_score":0.86068726,"about_ca_system_score_codex":0.000056068813,"about_ca_system_score_gemma":0.00030057912,"threshold_uncertainty_score":0.99998856},"labels":[],"label_agreement":null},{"id":"W4394935880","doi":"10.1016/j.bbih.2024.100773","title":"The association between depressive symptoms and high-sensitivity C-reactive protein: Is body mass index a moderator?","year":2024,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Moderation; Depressive symptoms; Index (typography); Body mass index; C-reactive protein; Association (psychology); Sensitivity (control systems); Internal medicine; Psychology; Medicine; Psychiatry; Social psychology; Computer science; Inflammation; Psychotherapist; World Wide Web","score_opus":0.021568294975704505,"score_gpt":0.3002434381432148,"score_spread":0.2786751431675103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394935880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877904,0.0003215709,0.0003866971,0.009076853,0.00023234436,0.0015148477,0.0002793798,0.0002704198,0.00012749748],"genre_scores_gemma":[0.9974494,0.000054837245,0.000021679023,0.0015147355,0.00009442938,0.00019753145,0.00001938168,0.000048909667,0.0005991215],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99621147,0.001559094,0.0003800638,0.00058553653,0.0005771347,0.0006866811],"domain_scores_gemma":[0.9968773,0.0020984442,0.00025429597,0.0004884793,0.00007107361,0.00021037392],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001224947,0.00029566497,0.0003397703,0.00012802218,0.0014129655,0.00049685565,0.00025516716,0.00020863037,0.000012104437],"category_scores_gemma":[0.000743406,0.00024462218,0.0001002231,0.00045909404,0.00021144569,0.00043018046,0.00016518652,0.0010285999,0.00002789029],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002306019,0.0007743901,0.1348631,0.00038518145,0.0002116829,0.00017612835,0.009978168,0.0000071786917,0.65211296,0.010328503,0.004579106,0.18635303],"study_design_scores_gemma":[0.0010824435,0.00034954067,0.90413207,0.00020537389,0.00005245711,0.00002211901,0.00053420675,0.0007347024,0.08689392,0.002313042,0.0031228627,0.00055726356],"about_ca_topic_score_codex":0.0019775135,"about_ca_topic_score_gemma":0.00016526898,"teacher_disagreement_score":0.769269,"about_ca_system_score_codex":0.00051578943,"about_ca_system_score_gemma":0.00042754592,"threshold_uncertainty_score":0.99988705},"labels":[],"label_agreement":null},{"id":"W4394995638","doi":"10.3390/neuroglia5020007","title":"Microbiome-Glia Crosstalk: Bridging the Communication Divide in the Central Nervous System","year":2024,"lang":"en","type":"article","venue":"Neuroglia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of the Fraser Valley","funders":"","keywords":"Bridging (networking); Crosstalk; Central nervous system; Neuroscience; Computer science; Communication; Biology; Engineering; Psychology; Computer network; Electronic engineering","score_opus":0.020527747761466774,"score_gpt":0.2566082537559794,"score_spread":0.23608050599451263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394995638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98630935,0.0007803697,0.00009792427,0.008371614,0.000783977,0.000459234,0.00002928477,0.0002759581,0.0028922863],"genre_scores_gemma":[0.99724,0.000049308823,0.000007362496,0.002160836,0.00009782489,0.000029198492,0.0000033216104,0.00002399423,0.00038815968],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99837303,0.0004678993,0.00021668233,0.00032791434,0.00022484602,0.00038964022],"domain_scores_gemma":[0.9987705,0.00050470745,0.000041880656,0.0006416076,0.000008680821,0.00003267479],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027952917,0.0001453423,0.00009768357,0.00007422653,0.0003319632,0.0006222252,0.0010023792,0.000040006827,0.000014503294],"category_scores_gemma":[0.00014051325,0.000086366934,0.00008786486,0.0006718856,0.00021646242,0.00017382526,0.00014596301,0.00037903097,0.00013774868],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005509483,0.00023218652,0.0013086548,0.0004288963,0.00001405341,0.00070495676,0.01661221,0.00042519905,0.8353779,0.043681893,0.054664407,0.046494562],"study_design_scores_gemma":[0.0020525062,0.00023937545,0.18133554,0.0011351611,0.00007799996,0.0016382218,0.0065019825,0.039595988,0.23767573,0.002181534,0.5261589,0.0014070249],"about_ca_topic_score_codex":0.00013012245,"about_ca_topic_score_gemma":0.000066790664,"teacher_disagreement_score":0.59770215,"about_ca_system_score_codex":0.000044484554,"about_ca_system_score_gemma":0.00003452412,"threshold_uncertainty_score":0.60001326},"labels":[],"label_agreement":null},{"id":"W4395689370","doi":"10.1002/hup.2898","title":"Analysis of schizophrenia‐associated genetic markers in the HLA region as risk factors for tardive dyskinesia","year":2024,"lang":"en","type":"article","venue":"Human Psychopharmacology Clinical and Experimental","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation; Brain and Behavior Research Foundation","keywords":"Tardive dyskinesia; Single-nucleotide polymorphism; SNP; Schizophrenia (object-oriented programming); Genotype; Human leukocyte antigen; Dyskinesia; Medicine; Psychiatry; Psychology; Internal medicine; Clinical psychology; Genetics; Biology; Gene; Immunology; Disease","score_opus":0.05832295645562774,"score_gpt":0.41232138129574136,"score_spread":0.3539984248401136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395689370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976506,0.00065072736,0.000011400214,0.00020807805,0.00060110475,0.00046056288,0.000040938558,0.00004085889,0.00033567759],"genre_scores_gemma":[0.9985878,0.00023560591,0.000015606296,0.0009007678,0.00007862234,0.00007290932,0.000013070188,0.000014968949,0.00008068444],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99791396,0.00056666404,0.0005495077,0.0005794173,0.00014844835,0.00024198889],"domain_scores_gemma":[0.9981089,0.0015196718,0.00013623404,0.00014875084,0.000011669986,0.000074728065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035618895,0.00017907628,0.0003767679,0.00025108302,0.00016785029,0.00003890559,0.00027517017,0.00014574706,0.00020763355],"category_scores_gemma":[0.00017340032,0.000126922,0.00037391915,0.0006030627,0.00060297153,0.000062949024,0.000045062974,0.00028265806,0.000006500512],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01952528,0.009559126,0.43179303,0.00016508333,0.0050700917,0.00054801727,0.024609486,0.00030776468,0.43719092,0.005868499,0.050083954,0.015278754],"study_design_scores_gemma":[0.022459766,0.0034783517,0.9206733,0.000061470244,0.0019520804,0.000018576775,0.0058475556,0.008500148,0.029021828,0.0044227857,0.0026511836,0.0009129266],"about_ca_topic_score_codex":0.000047032703,"about_ca_topic_score_gemma":0.000018911167,"teacher_disagreement_score":0.4888803,"about_ca_system_score_codex":0.00001736581,"about_ca_system_score_gemma":0.0000211509,"threshold_uncertainty_score":0.5175729},"labels":[],"label_agreement":null},{"id":"W4395702099","doi":"10.1101/2024.04.26.24306425","title":"Associations between IL-6 and trajectories of depressive symptoms across the life course: Evidence from ALSPAC and UK Biobank cohorts","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Medical Research Council; National Institutes of Health; Department of Health and Social Care; University of Bristol; National Institute for Health and Care Research; UK Research and Innovation; Wellcome Trust","keywords":"Biobank; Life course approach; Longitudinal study; Depressive symptoms; Longitudinal data; Gerontology; Course (navigation); Psychology; Medicine; Demography; Psychiatry; Developmental psychology; Anxiety; Sociology; Bioinformatics; Biology; Engineering","score_opus":0.039253481480398034,"score_gpt":0.31954935220817293,"score_spread":0.2802958707277749,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395702099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98064005,0.011772965,0.00003221272,0.0020420316,0.00070007576,0.0004953289,0.0041664084,0.00008645225,0.00006444175],"genre_scores_gemma":[0.9980065,0.0013828103,0.000020309775,0.0001847849,0.00021761325,0.00004736426,0.000024091049,0.000031982236,0.00008450695],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.997695,0.00026657505,0.00041017096,0.00083220634,0.00047534212,0.00032065742],"domain_scores_gemma":[0.99619466,0.0027043936,0.00036366607,0.00053498975,0.000066119064,0.00013615997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003875864,0.0003133659,0.0005441935,0.000048669248,0.0002513971,0.0002876002,0.0005061239,0.0002763291,0.000023314735],"category_scores_gemma":[0.002700855,0.00022918175,0.000109891116,0.00023620742,0.0008127085,0.00008392103,0.0011165212,0.00066566956,0.0000068988124],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013763812,0.00003234125,0.97555304,0.00013496152,0.00023709318,0.000015535246,0.0065957955,0.000021797914,0.014572184,0.00025295516,0.0009590296,0.0016115025],"study_design_scores_gemma":[0.00016722028,0.000028276252,0.9606905,0.0004173968,0.00023323875,0.0000014790576,0.0001903741,0.000059090493,0.031712346,0.006111314,0.00012328144,0.00026548078],"about_ca_topic_score_codex":0.0004971618,"about_ca_topic_score_gemma":0.00020319183,"teacher_disagreement_score":0.017366454,"about_ca_system_score_codex":0.000020199168,"about_ca_system_score_gemma":0.0001783953,"threshold_uncertainty_score":0.93457603},"labels":[],"label_agreement":null},{"id":"W4395959748","doi":"10.1016/j.biopsych.2024.02.015","title":"Imaging Monoamine Oxidase B in Inflammatory Illnesses Comorbid With Major Depressive Disorder","year":2024,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase A; Medicine; Psychiatry; Neuroscience; Psychology; Internal medicine; Serotonin; Chemistry; Receptor; Enzyme; Biochemistry","score_opus":0.015714892631042594,"score_gpt":0.2581483517186579,"score_spread":0.24243345908761532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395959748","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989995,0.0038506454,0.00028856657,0.0023788747,0.000797407,0.0002721234,0.000019626212,0.00031952286,0.0020782046],"genre_scores_gemma":[0.99799895,0.0001048094,0.0002216103,0.001370728,0.00012132211,0.000059709466,0.000006353132,0.000022553659,0.000093942566],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985059,0.0001145823,0.00023307824,0.0006325063,0.00014161222,0.00037234923],"domain_scores_gemma":[0.9994241,0.0002116476,0.000043214604,0.00022427266,0.000010223438,0.00008655759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000079330704,0.00022899274,0.00017856191,0.00013358238,0.00010218259,0.00010511867,0.00028410705,0.00008838664,0.00018198497],"category_scores_gemma":[0.00013464995,0.00014254867,0.00006831405,0.00043748735,0.00029128493,0.00016745295,0.00008769198,0.0002870197,0.00011543694],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004950727,0.0008230071,0.8424134,0.00027778177,0.000023689667,0.0006945357,0.0003069045,0.00008894167,0.08732173,0.04170497,0.0050975955,0.020752372],"study_design_scores_gemma":[0.0055681434,0.0006247362,0.8885431,0.00078427035,0.000029831757,0.00028679072,0.0016378456,0.0022131961,0.018818384,0.02935426,0.049984757,0.0021546346],"about_ca_topic_score_codex":0.000019274632,"about_ca_topic_score_gemma":0.00006500777,"teacher_disagreement_score":0.06850334,"about_ca_system_score_codex":0.000019079456,"about_ca_system_score_gemma":0.000064423766,"threshold_uncertainty_score":0.58129656},"labels":[],"label_agreement":null},{"id":"W4396221809","doi":"10.1016/j.biopsych.2024.02.445","title":"210. Plasma Sphingomyelins as Novel Metabolic Correlates of Depression in a Clinical Population With Coronary Artery Disease","year":2024,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; Queensway-Carleton Hospital; University of Ottawa","funders":"","keywords":"Coronary artery disease; Depression (economics); Internal medicine; Medicine; Cardiology; Disease; Population","score_opus":0.04375964209348089,"score_gpt":0.3148964035808096,"score_spread":0.27113676148732874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396221809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99630874,0.0013599701,0.00010880471,0.00042664201,0.0010247476,0.00027159762,0.000034068216,0.00013394456,0.00033145858],"genre_scores_gemma":[0.9986751,0.00020448247,0.0004296567,0.00046802845,0.00013255436,0.000016667862,0.000019969879,0.000014812492,0.0000387316],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983826,0.00013614376,0.0004709515,0.0006059928,0.00017533042,0.00022894316],"domain_scores_gemma":[0.9991894,0.00036267706,0.00009029638,0.00021259418,0.000009074143,0.00013599142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017670548,0.00017510643,0.0002583182,0.00010523433,0.00004851458,0.000026152438,0.00020232868,0.00016758815,0.00008036699],"category_scores_gemma":[0.00034483682,0.00010799344,0.00013796744,0.00036672578,0.00019232319,0.00012014969,0.00006601195,0.000315252,0.00005663674],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009300905,0.00064636994,0.9771272,0.000037988928,0.00000976389,0.00003628414,0.000025152092,0.00007268643,0.0037804972,0.010434373,0.00007591425,0.006823673],"study_design_scores_gemma":[0.0008076824,0.00025215445,0.992208,0.00016502594,0.000012665355,0.00002795749,0.00003542282,0.0015271219,0.00013083448,0.004344268,0.00031925793,0.00016963325],"about_ca_topic_score_codex":0.00001156558,"about_ca_topic_score_gemma":0.000017477758,"teacher_disagreement_score":0.01508077,"about_ca_system_score_codex":0.000008324366,"about_ca_system_score_gemma":0.00007619205,"threshold_uncertainty_score":0.44038448},"labels":[],"label_agreement":null},{"id":"W4396573801","doi":"10.1093/cvr/cvae099","title":"Targeting macrophages with multifunctional nanoparticles to detect and prevent atherosclerotic cardiovascular disease","year":2024,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Netherlands Heart Institute; Australian Research Council","keywords":"Disease; Medicine; Atherosclerotic cardiovascular disease; Macrophage; Pathology; Biology; Biochemistry","score_opus":0.0532941799277914,"score_gpt":0.29765788622940315,"score_spread":0.24436370630161175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396573801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94458574,0.047929063,0.0050316295,0.0003824056,0.00020372316,0.0013788857,0.000023682484,0.000273187,0.00019169264],"genre_scores_gemma":[0.997712,0.00089892314,0.0004432307,0.00006912099,0.00019786155,0.0003168581,0.0000022718673,0.00007618635,0.0002835472],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9950572,0.00086763455,0.00018626275,0.001196752,0.0019349599,0.00075718045],"domain_scores_gemma":[0.9982485,0.0003506181,0.000008467118,0.000799636,0.00010680479,0.00048594573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021047364,0.00023608145,0.00032373558,0.00028719872,0.00046064839,0.00043347667,0.00029410515,0.000055046494,0.00005193634],"category_scores_gemma":[0.0009134785,0.00018520861,0.00057700876,0.0010879827,0.0003722256,0.0002101015,0.00028890654,0.0003991643,0.0002599344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004133001,0.00015207304,0.00025500054,0.0012972638,0.0033124066,0.0026675272,0.0012232874,0.06101729,0.65756345,0.0011012026,0.0020290038,0.2689682],"study_design_scores_gemma":[0.0034224219,0.00089702377,0.018325206,0.0012029231,0.00077056675,0.00030860587,0.0010688606,0.011164588,0.5974856,0.0023945796,0.36087325,0.0020863644],"about_ca_topic_score_codex":0.000040059593,"about_ca_topic_score_gemma":0.0000016079086,"teacher_disagreement_score":0.35884425,"about_ca_system_score_codex":0.000095357434,"about_ca_system_score_gemma":0.0001428464,"threshold_uncertainty_score":0.7552588},"labels":[],"label_agreement":null},{"id":"W4396676431","doi":"10.1002/jnr.25338","title":"<scp>IDO</scp> ‐1 inhibition improves outcome after fluid percussion injury in adult male rats","year":2024,"lang":"en","type":"article","venue":"Journal of Neuroscience Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Kynurenine pathway; Traumatic brain injury; Neuroprotection; Elevated plus maze; Open field; Hippocampus; Kynurenine; Pharmacology; Neocortex; Medicine; Pathological; Anesthesia; Internal medicine; Psychology; Anxiety; Chemistry; Tryptophan; Neuroscience; Biochemistry","score_opus":0.06375024206865747,"score_gpt":0.37898016038980453,"score_spread":0.31522991832114705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396676431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952391,0.00014184888,0.000033931632,0.0021117968,0.0010837736,0.0002429891,0.000011867472,0.000031602256,0.0011030985],"genre_scores_gemma":[0.9960485,0.0004974018,0.00004271911,0.0009044065,0.0001887904,0.000015204148,1.827215e-7,0.00002772781,0.0022750325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9952592,0.00060553185,0.0006767328,0.0006052008,0.0020060185,0.0008472735],"domain_scores_gemma":[0.998391,0.00072588224,0.00010135397,0.00026869174,0.0002113816,0.0003016952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020632085,0.00018887348,0.00024262807,0.0015392919,0.00021895752,0.0006136303,0.00065431185,0.00010902173,0.00003574723],"category_scores_gemma":[0.0073844926,0.0001367638,0.0001630206,0.002732166,0.00061955064,0.0015303461,0.00028235745,0.0014760821,0.00013084491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005134889,0.00014894106,0.00064866315,0.000080798134,3.7854727e-7,0.0015995445,0.0005352635,0.000008719649,0.99078035,0.000245617,0.0026545608,0.0032458382],"study_design_scores_gemma":[0.0007093407,0.0015590678,0.053261198,0.0005425652,0.000004561716,0.0015782483,0.000931507,0.0041885925,0.9221703,0.00250712,0.012349525,0.00019796722],"about_ca_topic_score_codex":0.0000066585294,"about_ca_topic_score_gemma":0.0000039559186,"teacher_disagreement_score":0.06861002,"about_ca_system_score_codex":0.00015484368,"about_ca_system_score_gemma":0.00036307538,"threshold_uncertainty_score":0.8840461},"labels":[],"label_agreement":null},{"id":"W4396686938","doi":"10.1101/2024.05.05.24306882","title":"Is amnestic mild cognitive impairment a neuro-immune condition?","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Cognitive impairment; Cognition; Psychology; Neuroscience; Cognitive psychology; Immune system; Medicine; Immunology","score_opus":0.03520632585099574,"score_gpt":0.3050945650163901,"score_spread":0.26988823916539434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396686938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857382,0.00081542425,0.00007114696,0.0038892524,0.0025596072,0.0010499005,0.0005420965,0.00049026316,0.004844109],"genre_scores_gemma":[0.9919254,0.0001946652,0.000025473373,0.0054001054,0.00017939629,0.0002730153,0.00003844474,0.00008888511,0.0018746041],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969788,0.00022472195,0.00045701506,0.0013076755,0.0005355399,0.00049625314],"domain_scores_gemma":[0.99843377,0.0005985344,0.00017597812,0.0005754959,0.000051862407,0.00016433698],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00017374047,0.0004905532,0.00042485894,0.00028217505,0.00014366547,0.00022753517,0.00058493344,0.00023372473,0.0010108409],"category_scores_gemma":[0.00065351336,0.00045718515,0.00035869214,0.000386644,0.00033030994,0.000052914595,0.0012412329,0.0011991743,0.0027137226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00172872,0.008152633,0.0202247,0.016710237,0.0012744002,0.013092859,0.039774083,0.00059138204,0.71418524,0.030369386,0.1399478,0.013948541],"study_design_scores_gemma":[0.0036970824,0.00073773006,0.124729745,0.0037465554,0.0004996129,0.00023307638,0.00077858544,0.0038191704,0.71400476,0.13678487,0.007834461,0.0031343645],"about_ca_topic_score_codex":0.000028425766,"about_ca_topic_score_gemma":0.0000047027033,"teacher_disagreement_score":0.13211335,"about_ca_system_score_codex":0.000055807002,"about_ca_system_score_gemma":0.00018716806,"threshold_uncertainty_score":0.99990237},"labels":[],"label_agreement":null},{"id":"W4396705065","doi":"10.3389/frai.2024.1366055","title":"Innova4Health: an integrated approach for prevention of recurrence and personalized treatment of Major Depressive Disorder","year":2024,"lang":"en","type":"article","venue":"Frontiers in Artificial Intelligence","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"European Regional Development Fund","keywords":"Major depressive disorder; Medicine; Psychotherapist; Psychiatry; Psychology; Cognition","score_opus":0.07825888170383026,"score_gpt":0.34496134609420415,"score_spread":0.2667024643903739,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396705065","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.27816206,0.0029344265,0.71709746,0.00008658563,0.000512139,0.0009760122,0.00009371963,0.000038595295,0.00009900835],"genre_scores_gemma":[0.97565526,0.00062436523,0.023348087,0.000016839638,0.00002543119,0.00014727577,0.000026416883,0.00001849169,0.00013783475],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984929,0.00014059612,0.00048334483,0.00050572224,0.00015080003,0.00022662469],"domain_scores_gemma":[0.9994613,0.00014326701,0.000118026626,0.00016943846,0.00005483789,0.000053117838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016435915,0.00016398405,0.0002998577,0.00028945002,0.000056696772,0.000034311255,0.00017248506,0.000084867585,0.000016340966],"category_scores_gemma":[0.0002551976,0.00014065934,0.00007660403,0.00072305894,0.0004218836,0.00019890243,0.000018793167,0.00008559227,7.1355595e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006353083,0.0009629546,0.0007049636,0.0003647738,0.000019691928,0.0000029438736,0.0052402574,0.00025501693,0.023396427,0.02283194,0.00008737364,0.94549835],"study_design_scores_gemma":[0.00041486078,0.0018031552,0.0002394073,0.00028171943,0.00003835529,0.0000060170155,0.007554692,0.2538511,0.6712513,0.062915325,0.001275674,0.00036841203],"about_ca_topic_score_codex":0.00010382845,"about_ca_topic_score_gemma":0.000042600273,"teacher_disagreement_score":0.94512993,"about_ca_system_score_codex":0.000052052368,"about_ca_system_score_gemma":0.000094272305,"threshold_uncertainty_score":0.5735921},"labels":[],"label_agreement":null},{"id":"W4396826611","doi":"10.5267/j.ccl.2024.3.004","title":"Inhibition activity of triazoles as a new family for the inhibition of the Indoleamine 2,3-dioxygenase 1 IDO1 protein using 2D-QSAR approach","year":2024,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Indoleamine 2,3-dioxygenase; Quantitative structure–activity relationship; Stereochemistry; Dioxygenase; Tryptophan; Combinatorial chemistry; Computational chemistry; Biochemistry; Enzyme; Amino acid","score_opus":0.058337884237766126,"score_gpt":0.28774926272199935,"score_spread":0.22941137848423324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396826611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99122727,0.00046668996,0.005912376,0.0011378983,0.00018753785,0.0008811043,0.00007890822,0.000043168322,0.00006504209],"genre_scores_gemma":[0.99950546,0.000014153702,0.00005905133,0.00013946625,0.00017021429,0.000063019375,0.000009698547,0.000021040323,0.00001787035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876916,0.000059617498,0.00026260345,0.00036800205,0.00032805052,0.00021256518],"domain_scores_gemma":[0.99928504,0.00016043024,0.00018594893,0.0002990118,0.000023186469,0.00004636581],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001616235,0.00018478262,0.00017308722,0.0000373892,0.000110305926,0.00004797744,0.00020248315,0.000064110405,0.000009771832],"category_scores_gemma":[0.00038448683,0.00012281074,0.00022633576,0.00042089928,0.00026404028,0.00014603042,0.00008249611,0.00026888712,0.0000012757343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008765491,0.00012106128,0.0000013164192,0.00088005216,0.000009139794,7.742679e-7,0.00021779056,0.0001598012,0.99143296,0.00005108994,0.0005510404,0.0064872894],"study_design_scores_gemma":[0.00070139597,0.000006147529,0.000031705713,0.0004000471,0.000018311586,0.0000065291447,0.000101939055,0.0022794765,0.99577445,0.00015506758,0.00039383303,0.00013108666],"about_ca_topic_score_codex":0.00001479231,"about_ca_topic_score_gemma":2.0752563e-7,"teacher_disagreement_score":0.008278211,"about_ca_system_score_codex":0.000056430777,"about_ca_system_score_gemma":0.00016459172,"threshold_uncertainty_score":0.5008077},"labels":[],"label_agreement":null},{"id":"W4396894859","doi":"10.1038/s41589-024-01619-z","title":"The β-subunit of tryptophan synthase is a latent tyrosine synthase","year":2024,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Gouvernement du Québec","funders":"National Institute of General Medical Sciences; Fonds de recherche du Québec – Nature et technologies; Helen Hay Whitney Foundation; California Institute of Technology; U.S. Department of Health and Human Services; National Institutes of Health; National Science Foundation","keywords":"Tryptophan synthase; ATP synthase; Protein subunit; Biochemistry; Tyrosine; Chemistry; Enzyme; Biology; Computational biology; Tryptophan; Gene; Amino acid","score_opus":0.01605443429116789,"score_gpt":0.2871128045518368,"score_spread":0.2710583702606689,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396894859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97929597,0.008888319,0.000030885734,0.008171605,0.0009845182,0.0002121681,0.00017807026,0.00017168935,0.0020667636],"genre_scores_gemma":[0.9971625,0.0003395681,0.000043932632,0.00199942,0.00013954476,0.000015244167,0.000010604819,0.000018018996,0.00027115233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987222,0.000075130614,0.00024239086,0.0004720051,0.00013961834,0.00034867311],"domain_scores_gemma":[0.9983625,0.0011467844,0.000050247396,0.00032046984,0.000031657106,0.00008835516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001172007,0.00017763014,0.00020152895,0.00006334768,0.00007922977,0.00003587248,0.0004729199,0.00047038347,0.0002114653],"category_scores_gemma":[0.001201993,0.000106277315,0.00015919251,0.00044555648,0.0005668997,0.000040719046,0.00012443974,0.0007562016,0.000082636514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078389654,0.000063711654,0.000017139053,0.00003517656,0.0000124855305,0.00001685175,0.00005555079,1.03299826e-7,0.96742284,0.017112887,0.004815498,0.010369343],"study_design_scores_gemma":[0.00021668113,0.00005611185,0.000020985135,0.000033883218,0.00000882846,0.000024268647,0.000012457172,0.00014868945,0.9265492,0.0042982963,0.06851027,0.00012035088],"about_ca_topic_score_codex":0.0000042249985,"about_ca_topic_score_gemma":0.0000011179047,"teacher_disagreement_score":0.063694775,"about_ca_system_score_codex":0.00002457206,"about_ca_system_score_gemma":0.000048589605,"threshold_uncertainty_score":0.43338633},"labels":[],"label_agreement":null},{"id":"W4396924867","doi":"10.1177/11786469241248287","title":"A Review of the Evidence for Tryptophan and the Kynurenine Pathway as a Regulator of Stem Cell Niches in Health and Disease","year":2024,"lang":"en","type":"review","venue":"International Journal of Tryptophan Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"St Vincent's Curran Foundation; Multiple Sclerosis Australia; University of New South Wales; St. Vincent's Clinic Foundation","keywords":"Quinolinic acid; Biology; Stem cell; Cell biology; Kynurenine; Progenitor cell; Induced pluripotent stem cell; Embryonic stem cell; Biochemistry","score_opus":0.21016456408079046,"score_gpt":0.47530825907568536,"score_spread":0.2651436949948949,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396924867","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009104321,0.9903024,0.000008287661,0.006562974,0.00038440843,0.0016671211,0.00011527021,0.000003697115,0.00004540345],"genre_scores_gemma":[0.0053484607,0.99329686,0.00003862997,0.0005039955,0.000168936,0.00008283286,0.0000016035549,0.000035716817,0.00052295765],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9940543,0.0018829263,0.0016853928,0.00043189304,0.0016266467,0.00031880088],"domain_scores_gemma":[0.9929453,0.0045338217,0.0013313217,0.0004051199,0.00050919614,0.00027521062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004267794,0.00028456902,0.0012774611,0.00058646273,0.000086327185,0.00010095768,0.0017499044,0.000096831354,0.000018705392],"category_scores_gemma":[0.005699458,0.00014390086,0.0006663962,0.00078353565,0.00089210906,0.00016858142,0.0005338721,0.00091138633,0.0000021428561],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015859482,0.0003247751,0.000016791006,0.2521746,0.00018945512,0.00007929368,0.0008383076,0.0000013100591,0.0003075319,0.017545963,0.005498199,0.7214378],"study_design_scores_gemma":[0.0027443182,0.00060410553,0.000038030215,0.56349635,0.00016226897,0.0003444467,0.00024077727,0.000060663817,0.0011613687,0.010232887,0.420628,0.0002867695],"about_ca_topic_score_codex":0.00001898159,"about_ca_topic_score_gemma":0.0000052416694,"teacher_disagreement_score":0.72115105,"about_ca_system_score_codex":0.00015268831,"about_ca_system_score_gemma":0.002839272,"threshold_uncertainty_score":0.6823196},"labels":[],"label_agreement":null},{"id":"W4398145370","doi":"10.1093/toxsci/kfae058","title":"The use of PD-1 functional knockout rats to study idiosyncratic adverse reactions to nevirapine","year":2024,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; University of Toronto","funders":"Canadian Institutes of Health Research; Pfizer Canada; Government of Canada; Wellcome Trust","keywords":"Nevirapine; Adverse effect; Pharmacology; Medicine; Knockout mouse; Chemistry; Human immunodeficiency virus (HIV); Internal medicine; Immunology; Viral load","score_opus":0.18900272234247392,"score_gpt":0.3444204495863025,"score_spread":0.1554177272438286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398145370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99138874,0.00003919564,0.00030195733,0.005797776,0.00063757214,0.0006349456,0.0000076296255,0.000115842435,0.0010763332],"genre_scores_gemma":[0.9958736,0.00001326937,0.00025835255,0.0018515834,0.000051820887,0.00006975181,1.3017699e-7,0.000003958866,0.0018775456],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981804,0.00022181435,0.00026457876,0.00050914515,0.0005160397,0.00030800697],"domain_scores_gemma":[0.99800813,0.0016017574,0.00003517703,0.00017784207,0.000024397055,0.00015267845],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054318807,0.00011693791,0.00012675374,0.0001119642,0.0006679215,0.00020699576,0.00042058853,0.000035477708,0.00052383414],"category_scores_gemma":[0.0025688591,0.00006191292,0.00006906811,0.0018159732,0.00042248977,0.00025370816,0.00017336785,0.00012670075,0.0003230435],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013136053,0.00088285154,0.00053624006,0.000011674044,0.000013705631,0.00004307088,0.00097177323,0.0053624017,0.92585534,0.019930052,0.01032404,0.035937473],"study_design_scores_gemma":[0.0006837637,0.011875802,0.2201202,0.00010515184,0.000041049247,0.000051403906,0.004729965,0.0050332556,0.20455548,0.0063930214,0.54548514,0.0009257834],"about_ca_topic_score_codex":0.000013212415,"about_ca_topic_score_gemma":0.000049871815,"teacher_disagreement_score":0.7212999,"about_ca_system_score_codex":0.000029184748,"about_ca_system_score_gemma":0.00007672043,"threshold_uncertainty_score":0.57356167},"labels":[],"label_agreement":null},{"id":"W4398177693","doi":"10.1002/2211-5463.13814","title":"<scp>CSF</scp> amino acid profiles in <scp>ICV</scp>‐streptozotocin‐induced sporadic Alzheimer's disease in male Wistar rat: a metabolomics and systems biology perspective","year":2024,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Tehran University of Medical Sciences and Health Services","keywords":"Streptozotocin; Disease; Metabolomics; Perspective (graphical); Biology; Amino acid; Alzheimer's disease; Biochemistry; Pharmacology; Medicine; Endocrinology; Bioinformatics; Internal medicine; Diabetes mellitus; Computer science","score_opus":0.04216077736073297,"score_gpt":0.3021810823977557,"score_spread":0.2600203050370227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398177693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9769444,0.014011895,0.00000819597,0.00040494095,0.0007704429,0.0030252463,0.0003133724,0.00012898355,0.0043925326],"genre_scores_gemma":[0.99731094,0.00042944207,0.000073264775,0.000359641,0.000114958995,0.0005148335,0.000039793893,0.00006753829,0.0010896096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963797,0.0005012976,0.0005335591,0.0015303189,0.0002485287,0.0008066279],"domain_scores_gemma":[0.99823046,0.00070599676,0.0001585616,0.00053319073,0.000052153093,0.00031962857],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047571585,0.0004819533,0.0006455289,0.0005396027,0.0001488872,0.0006714561,0.0009091191,0.00023591993,0.00002537041],"category_scores_gemma":[0.0014728808,0.00043304006,0.00011408402,0.0012158544,0.00041206594,0.00069096935,0.0005227377,0.0005070669,0.00017155932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023798113,0.001584964,0.10567115,0.0006191607,0.00029041633,0.0030144977,0.019706065,0.000094446856,0.7363239,0.11502286,0.014575286,0.0028592506],"study_design_scores_gemma":[0.011828446,0.0016448252,0.22229722,0.0016903012,0.00047975138,0.00034054686,0.07709703,0.010954776,0.55324966,0.01694252,0.10196401,0.0015108912],"about_ca_topic_score_codex":0.0011143557,"about_ca_topic_score_gemma":0.00026586276,"teacher_disagreement_score":0.18307424,"about_ca_system_score_codex":0.00014924761,"about_ca_system_score_gemma":0.00038505334,"threshold_uncertainty_score":0.9998121},"labels":[],"label_agreement":null},{"id":"W4398219177","doi":"10.3389/fimmu.2024.1352251","title":"Differences in IDO1+ dendritic cells and soluble CTLA-4 are associated with differential clinical responses to methotrexate treatment in rheumatoid arthritis","year":2024,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Izaak Walton Killam Health Centre; Dalhousie University","funders":"IWK Health Centre; Canadian Institutes of Health Research; Dalhousie University; Nova Scotia Health Research Foundation","keywords":"Rheumatoid arthritis; Medicine; Immunology; CD86; Methotrexate; Dendritic cell; Arthritis; CD40; Flow cytometry; Antigen; Immune system; Cytotoxic T cell; T cell; Biology","score_opus":0.028859546136139003,"score_gpt":0.2811740063711328,"score_spread":0.2523144602349938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398219177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928115,0.0039998763,0.0002673789,0.00051151734,0.0018253091,0.00041225093,0.000029832281,0.00007018895,0.00007211879],"genre_scores_gemma":[0.9921421,0.0067874803,0.0003303292,0.00011735627,0.000011063421,0.000108062115,0.0000035445628,0.000025471978,0.0004746222],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99696296,0.001115014,0.00050688244,0.00072884344,0.00013049153,0.0005558245],"domain_scores_gemma":[0.9986378,0.0010115782,0.000069833084,0.00020445713,0.000010137242,0.00006620616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002626213,0.00025393226,0.00066774694,0.0006720576,0.00005641443,0.00009003776,0.00022113153,0.00021441477,0.000032030453],"category_scores_gemma":[0.0006694373,0.00021371432,0.00005857849,0.0006494798,0.00040418273,0.00012306379,0.00009318947,0.00037404368,0.000012758346],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002958298,0.0017515107,0.8513867,0.000046877558,0.00017545471,0.0023504256,0.0051966025,0.00001286216,0.06341489,0.00049529946,0.0014361494,0.07077493],"study_design_scores_gemma":[0.0063660457,0.0015815127,0.9590823,0.0010835025,0.0000102907725,0.0000373852,0.0019947994,0.0009960636,0.025793556,0.001576212,0.000876944,0.0006013594],"about_ca_topic_score_codex":0.00018889418,"about_ca_topic_score_gemma":0.0018607271,"teacher_disagreement_score":0.107695624,"about_ca_system_score_codex":0.00016827579,"about_ca_system_score_gemma":0.00010731807,"threshold_uncertainty_score":0.8715017},"labels":[],"label_agreement":null},{"id":"W4398232807","doi":"10.26685/urncst.565","title":"Increasing Ambient GABA Levels in the Hippocampus to Improve Cognition in a Mouse Model of Schizophrenia: A Research Protocol","year":2024,"lang":"en","type":"article","venue":"Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Hippocampus; Schizophrenia (object-oriented programming); Neuroscience; Cognition; Psychology; Pharmacology; Medicine; Psychiatry","score_opus":0.12980461560007023,"score_gpt":0.45020414520814583,"score_spread":0.3203995296080756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398232807","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95862424,0.0001376189,0.000012262585,0.03418772,0.000064978936,0.00674579,0.000006430253,0.000022359523,0.00019858633],"genre_scores_gemma":[0.9979314,0.0003504706,0.00026115167,0.00016165212,0.000035698566,0.0012105821,1.329863e-7,0.0000088198785,0.000040062427],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99452424,0.0012274187,0.0007490666,0.00080919,0.001624429,0.0010656663],"domain_scores_gemma":[0.9967715,0.0023913158,0.00007038665,0.00023502439,0.00032390736,0.00020785832],"candidate_categories":["metaresearch","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.021699795,0.00015331885,0.00028097245,0.003038672,0.00052574644,0.00043704372,0.00096392044,0.00022746001,0.0000029288858],"category_scores_gemma":[0.010291949,0.000095140116,0.000046727902,0.0070863627,0.004315764,0.00054297695,0.00064434967,0.00475567,0.000007705605],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000788309,0.00063519867,0.0025549247,0.00011793185,0.0000056721483,0.0003113565,0.0003482666,0.000018234212,0.72123283,0.02260552,0.00011880626,0.25126296],"study_design_scores_gemma":[0.0028518245,0.0013732116,0.0037643998,0.0008212309,0.0000024397443,0.00036897225,0.0018490069,0.03466435,0.033783987,0.9201828,0.00010527615,0.00023247683],"about_ca_topic_score_codex":0.00009428858,"about_ca_topic_score_gemma":0.000500409,"teacher_disagreement_score":0.8975773,"about_ca_system_score_codex":0.00018575818,"about_ca_system_score_gemma":0.0008973052,"threshold_uncertainty_score":0.9983939},"labels":[],"label_agreement":null},{"id":"W4399143003","doi":"10.1016/j.biopsych.2024.05.017","title":"Omics Approaches to Investigate the Pathogenesis of Suicide","year":2024,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institute of Mental Health; National Institute on Aging; National Institutes of Health; U.S. Department of Veterans Affairs; Canadian Institutes of Health Research; Columbia University","keywords":"Epigenome; Epigenetics; Biology; Transcriptome; Genomics; Omics; Computational biology; Biomarker; Bioinformatics; Genetics; Genome; Gene; DNA methylation; Gene expression","score_opus":0.41579575441778094,"score_gpt":0.3511583114816878,"score_spread":0.06463744293609314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399143003","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00062680896,0.9948877,0.000013600844,0.00096493226,0.001261306,0.0008308492,0.0002160969,0.0001088128,0.0010899004],"genre_scores_gemma":[0.00029946837,0.9970438,0.00053307525,0.0014984695,0.0002809952,0.00012370724,0.000016133774,0.000039411676,0.00016496604],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99771285,0.0004176336,0.000576948,0.0007885517,0.0001672448,0.0003367513],"domain_scores_gemma":[0.9987896,0.00033251612,0.00019783743,0.00054187,0.00000606926,0.00013209501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026477204,0.0004201569,0.0009280172,0.00011674319,0.00008387747,0.000044582648,0.0010443332,0.00039198596,0.000025837613],"category_scores_gemma":[0.0004394159,0.00018925787,0.0006738135,0.0008526368,0.00038273167,0.000016986514,0.0003201018,0.00040687967,0.00039142935],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021128535,0.00022280139,0.00005852,0.008508068,0.00006845785,0.000008097623,0.00006496789,0.0000023647492,0.00034662214,0.08907105,0.008443825,0.8931841],"study_design_scores_gemma":[0.000054034863,0.00013510372,0.000087365384,0.0015878457,0.00015394861,0.000023062263,0.000037884947,0.0000024253072,0.000034445773,0.008771992,0.98871946,0.00039240636],"about_ca_topic_score_codex":0.0000031261536,"about_ca_topic_score_gemma":0.0000035490623,"teacher_disagreement_score":0.98027563,"about_ca_system_score_codex":0.000019266627,"about_ca_system_score_gemma":0.00019911489,"threshold_uncertainty_score":0.7717712},"labels":[],"label_agreement":null},{"id":"W4399215495","doi":"10.1016/j.encep.2024.04.004","title":"A replication study of sHLA-E influence on schizophrenia and bipolar disorder","year":2024,"lang":"en","type":"article","venue":"L Encéphale","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"South African Medical Association; Agence Nationale de la Recherche; Fondation FondaMental; Institut National de la Santé et de la Recherche Médicale; Providence Health Care","keywords":"Bipolar disorder; Schizophrenia (object-oriented programming); Replication (statistics); Disease; Psychiatry; Population; Human leukocyte antigen; Psychology; Medicine; Immunology; Virology; Internal medicine; Antigen; Cognition","score_opus":0.019044533747006973,"score_gpt":0.2797693931417622,"score_spread":0.2607248593947552,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399215495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99552625,0.0006724068,0.000022895005,0.00010245038,0.00005276599,0.00027963746,0.000004770492,0.00012467024,0.0032141416],"genre_scores_gemma":[0.9988568,0.000072404146,0.000029641698,0.000106390784,0.000013269546,0.000024963669,3.5942892e-7,0.000019280536,0.0008769],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991255,0.00004545423,0.00012944425,0.00043675027,0.00015575632,0.00010713784],"domain_scores_gemma":[0.99942994,0.00011305559,0.000029804916,0.00038297524,0.000007758844,0.000036440466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007589931,0.000085744214,0.00008744412,0.00011805052,0.000048208032,0.000035306763,0.00012047897,0.000027675362,0.0000555792],"category_scores_gemma":[0.00027014618,0.00007271198,0.000019202565,0.00034970508,0.00007232655,0.000112242495,0.000044317905,0.000084270345,0.00007242285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014348446,0.0013472723,0.010911836,0.00017837861,0.000019405004,0.000039183713,0.0039941818,0.00014338635,0.72154427,0.040436592,0.00055558886,0.22068642],"study_design_scores_gemma":[0.0050398335,0.003967355,0.40004745,0.00045401824,0.00005882234,0.00006222964,0.0020960527,0.005717683,0.43444577,0.0075164386,0.13942938,0.0011649838],"about_ca_topic_score_codex":0.000050608614,"about_ca_topic_score_gemma":0.000025576723,"teacher_disagreement_score":0.38913563,"about_ca_system_score_codex":0.0000057076527,"about_ca_system_score_gemma":0.000013560528,"threshold_uncertainty_score":0.29651082},"labels":[],"label_agreement":null},{"id":"W4399258553","doi":"10.1016/j.jpsychores.2024.111812","title":"Editorial: The Ma'anshan birth cohort study","year":2024,"lang":"en","type":"editorial","venue":"Journal of Psychosomatic Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Cohort; Psychology; Medicine; Demography; Sociology; Internal medicine","score_opus":0.055626639419922755,"score_gpt":0.4159431183365429,"score_spread":0.36031647891662016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399258553","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0072767735,0.0005915798,0.000007039972,0.0013731516,0.9855092,0.0014821163,0.000043824002,0.000043400894,0.0036728857],"genre_scores_gemma":[0.0069261547,0.0011082684,0.00001769916,0.00003801904,0.9858689,0.000080800055,0.0000016224794,0.00012892018,0.0058296355],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98286647,0.00267905,0.0014339646,0.000725428,0.011433124,0.0008619569],"domain_scores_gemma":[0.9873267,0.009488584,0.00064428494,0.0011589115,0.0010833303,0.0002981961],"candidate_categories":["metaresearch","scholarly_communication","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.010727227,0.00042688905,0.00083190115,0.0010654128,0.00045832832,0.0012435892,0.003557214,0.0005887054,0.000328431],"category_scores_gemma":[0.015816966,0.00024393307,0.00044202514,0.0020114433,0.0004949136,0.00025781855,0.0003488873,0.0072443555,0.0008061775],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018162093,0.0006049699,0.00013007976,0.0002752076,0.00013765275,0.00018172801,0.0011749478,0.0000016648613,0.0005839762,0.00004371923,0.996168,0.0005164257],"study_design_scores_gemma":[0.0010011866,0.0012561367,0.0002601758,0.000558039,0.000051511066,0.000023393954,0.0012909775,0.00001317577,0.00009506938,0.005646091,0.98956615,0.00023812342],"about_ca_topic_score_codex":0.000045254183,"about_ca_topic_score_gemma":0.00002807479,"teacher_disagreement_score":0.010349793,"about_ca_system_score_codex":0.00025911248,"about_ca_system_score_gemma":0.001358841,"threshold_uncertainty_score":0.9999718},"labels":[],"label_agreement":null},{"id":"W4399303000","doi":"10.1016/j.jad.2024.05.106","title":"Causal role of immune cells in major depressive disorder and bipolar disorder: Mendelian randomization (MR) study","year":2024,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Natural Science Foundation of China","keywords":"Mendelian randomization; Immune system; Medicine; Major depressive disorder; Immunology; Internal medicine; Bipolar disorder; Oncology; Biology; Genetics; Genotype; Gene","score_opus":0.005151409116029839,"score_gpt":0.2449933618523706,"score_spread":0.23984195273634076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399303000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98095524,0.016035121,0.0011333318,0.00020256679,0.00040376946,0.000991812,0.000024599838,0.00002952089,0.00022404647],"genre_scores_gemma":[0.99769074,0.002090603,0.000036676123,0.0000309291,0.00003608377,0.000025455967,0.0000014970067,0.000050395905,0.00003761156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973582,0.00060760777,0.0007728387,0.00043453084,0.0004831829,0.00034361484],"domain_scores_gemma":[0.9983523,0.0008810176,0.0003886243,0.00019401539,0.00008349942,0.00010056335],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00058386504,0.00031344668,0.00059891975,0.0008112031,0.000121108846,0.00009592709,0.00029518077,0.00010402059,0.000050704515],"category_scores_gemma":[0.0006598744,0.0002572458,0.0002181912,0.0010743598,0.00022434191,0.00061585766,0.0001031442,0.00047228127,0.0000047855833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026252202,0.0039449167,0.103252046,0.00031152958,0.0003748174,0.00011910464,0.015809195,0.004329891,0.68784535,0.00095353683,0.00011654589,0.18031782],"study_design_scores_gemma":[0.113329075,0.009957572,0.27161196,0.001361028,0.000846445,0.00019555348,0.08426151,0.018955555,0.46726516,0.020571541,0.008807603,0.0028370083],"about_ca_topic_score_codex":0.0004517171,"about_ca_topic_score_gemma":0.0012548679,"teacher_disagreement_score":0.22058022,"about_ca_system_score_codex":0.000056686764,"about_ca_system_score_gemma":0.00011255615,"threshold_uncertainty_score":0.99998796},"labels":[],"label_agreement":null},{"id":"W4399305932","doi":"10.1016/j.freeradbiomed.2024.04.186","title":"Donepezil-loaded extracellular vesicles to mitigate both reactive oxygen species and inflammatory damage as a therapeutic approach for Alzheimer's disease","year":2024,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Donepezil; Reactive oxygen species; Extracellular vesicles; Disease; Inflammation; Extracellular; Alzheimer's disease; Pharmacology; Chemistry; Medicine; Biochemistry; Biology; Cell biology; Pathology; Internal medicine; Dementia","score_opus":0.035156481231609665,"score_gpt":0.28918128610252003,"score_spread":0.2540248048709104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399305932","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9286602,0.045646027,0.0039547337,0.018256335,0.00035511973,0.0012519707,0.00013057752,0.00020056336,0.0015444505],"genre_scores_gemma":[0.99578667,0.00040270606,0.00019315984,0.0028496333,0.00030396754,0.000086768276,0.00002818023,0.000019209741,0.00032969227],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987152,0.00012650232,0.00018972644,0.0005663722,0.000104766645,0.00029741696],"domain_scores_gemma":[0.9986928,0.00068505364,0.000030907977,0.00021003938,0.0000095013465,0.00037165958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022676153,0.00019132248,0.00025097484,0.000117369855,0.00016243146,0.000022820846,0.00018451917,0.00011681278,0.000047028043],"category_scores_gemma":[0.00066568697,0.00013073652,0.00004289175,0.00014328562,0.001438566,0.00007218331,0.000074529904,0.00018575607,0.000005588437],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051059766,0.000059332004,0.00019925286,0.00009634979,0.00006831274,0.000077337914,0.0008467498,8.221876e-7,0.8847072,0.09893746,0.0018269193,0.012669635],"study_design_scores_gemma":[0.009691972,0.0031754118,0.05356964,0.00051754963,0.00073655165,0.00014600516,0.0018340292,0.0044309706,0.23674072,0.19157113,0.4961718,0.0014141898],"about_ca_topic_score_codex":0.0000079761085,"about_ca_topic_score_gemma":0.0000017329892,"teacher_disagreement_score":0.6479665,"about_ca_system_score_codex":0.000008982058,"about_ca_system_score_gemma":0.000050927392,"threshold_uncertainty_score":0.533128},"labels":[],"label_agreement":null},{"id":"W4399390729","doi":"10.1038/s41380-024-02619-0","title":"Shared and unique transcriptomic signatures of antidepressant and probiotics action in the mammalian brain","year":2024,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lallemand (Canada); McGill University; Douglas Mental Health University Institute","funders":"Agency for Science, Technology and Research; Hope for Depression Research Foundation","keywords":"Prefrontal cortex; Neuroscience; Dentate gyrus; Infralimbic cortex; Transcriptome; Basolateral amygdala; Biology; Anterior cingulate cortex; Antidepressant; Amygdala; Mood disorders; Cingulate cortex; Psychology; Hippocampus; Genetics; Psychiatry; Gene expression; Gene; Anxiety; Cognition; Central nervous system","score_opus":0.014717018013067388,"score_gpt":0.26717801907519634,"score_spread":0.25246100106212893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399390729","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885021,0.0032636235,0.00039256268,0.0068965456,0.00023782853,0.0002962813,0.000018279903,0.000032827564,0.00035998493],"genre_scores_gemma":[0.99793756,0.00008584722,0.00027370403,0.001644112,0.000014166344,0.0000063762473,0.0000021077608,0.0000145590575,0.000021576181],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991966,0.00014936383,0.00013249813,0.00027862162,0.00011649032,0.000126453],"domain_scores_gemma":[0.99974644,0.00005953763,0.000022619055,0.00014274883,0.0000042688002,0.000024359573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013006561,0.00010377817,0.00009098696,0.000106149855,0.000035778252,0.000075761825,0.00012909145,0.000063800166,0.0000074247073],"category_scores_gemma":[0.00003580778,0.00007742204,0.00003860947,0.00025405918,0.00010546303,0.000080143654,0.000016355942,0.00020411886,9.061424e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004183015,0.0000730814,0.00052283396,0.0003613607,0.0000061855935,0.000042482283,0.0008630196,0.000031058447,0.9632681,0.031644423,0.0013794089,0.0017662434],"study_design_scores_gemma":[0.00236754,0.000600996,0.09265018,0.0008510373,0.000063224106,0.00031093069,0.0022167137,0.0048804097,0.8302658,0.060268287,0.0046981596,0.0008267264],"about_ca_topic_score_codex":0.0000114056265,"about_ca_topic_score_gemma":0.00006501345,"teacher_disagreement_score":0.13300228,"about_ca_system_score_codex":0.0000040162067,"about_ca_system_score_gemma":0.000030282072,"threshold_uncertainty_score":0.3157179},"labels":[],"label_agreement":null},{"id":"W4399492469","doi":"10.3390/ijms25126357","title":"Astroglial Dysfunctions in Mood Disorders and Rodent Stress Models: Consequences on Behavior and Potential as Treatment Target","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Campbell Family Mental Health Research Institute","keywords":"Major depressive disorder; Antidepressant; Anxiety; Astrocyte; Depression (economics); Psychology; Mood disorders; Chronic stress; Mood; Neuroscience; Psychiatry; Clinical psychology; Central nervous system","score_opus":0.02017517595003802,"score_gpt":0.2929239340565729,"score_spread":0.27274875810653487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399492469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939351,0.0005907181,0.0009076165,0.0027067056,0.0008022529,0.00009201349,0.000021791298,0.000010320776,0.0009334732],"genre_scores_gemma":[0.9988479,0.00060901797,0.00032608176,0.0001277592,0.000043764863,0.0000068484287,5.675102e-7,0.0000049295054,0.000033132495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987586,0.000057643603,0.0002118951,0.0002587114,0.00057881547,0.0001343073],"domain_scores_gemma":[0.9997226,0.000066626584,0.00007047429,0.000040017778,0.000031289306,0.000068965455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013644226,0.00010692387,0.00009777144,0.00034713998,0.00007521517,0.00031885787,0.00024480178,0.000028203845,0.000026901493],"category_scores_gemma":[0.000055890567,0.000079678735,0.000061214036,0.00014560524,0.00047754587,0.00037812875,0.000040002855,0.00010543095,0.000002227534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006062979,0.0022082157,0.0121533405,0.000027168639,0.00019059076,0.0048835315,0.003799613,0.11903417,0.563211,0.14688587,0.000061078405,0.14693908],"study_design_scores_gemma":[0.007885756,0.009899093,0.025427246,0.0009729019,0.00015538817,0.0050514084,0.0076230564,0.07951946,0.62023294,0.24068798,0.0012533454,0.0012914522],"about_ca_topic_score_codex":0.00007161395,"about_ca_topic_score_gemma":0.000058808237,"teacher_disagreement_score":0.14564763,"about_ca_system_score_codex":0.000047239348,"about_ca_system_score_gemma":0.00013835271,"threshold_uncertainty_score":0.32492045},"labels":[],"label_agreement":null},{"id":"W4399577845","doi":"10.3390/antiox13060709","title":"The Underlying Neurobiological Mechanisms of Psychosis: Focus on Neurotransmission Dysregulation, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction","year":2024,"lang":"en","type":"article","venue":"Antioxidants","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"University of Alberta; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Psychosis; Neuroinflammation; Neurochemistry; Schizophrenia (object-oriented programming); Neuroscience; Dopamine; Psychiatry; Psychology; Immune dysregulation; Medicine; Antipsychotic; Bioinformatics; Neurology; Biology; Internal medicine; Disease","score_opus":0.032472000343099085,"score_gpt":0.279754590772586,"score_spread":0.24728259042948694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399577845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9748998,0.00018258195,0.018669898,0.0034093144,0.0014241956,0.000558504,0.000019363453,0.00021390013,0.00062241976],"genre_scores_gemma":[0.99912226,0.0003126322,0.00010638049,0.00013210383,0.0000724645,0.000010537709,0.000002496022,0.000020724932,0.00022040053],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984615,0.0002457264,0.00030106734,0.00049946,0.0002751629,0.00021707105],"domain_scores_gemma":[0.99881494,0.0007812122,0.00009365638,0.00021212657,0.00002670944,0.00007135861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001038894,0.00017705954,0.00013171218,0.00010056726,0.00032550367,0.00015806915,0.00017646565,0.00008629436,0.000022156977],"category_scores_gemma":[0.00040519168,0.000116855816,0.00007083674,0.00035985684,0.00014936483,0.000233445,0.000032742555,0.00020324174,0.000021434273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013692192,0.000040049796,0.000028409799,0.000024989551,0.00000642972,0.000007136116,0.00014092609,0.00005635134,0.9379541,0.04506926,0.0005368889,0.015998486],"study_design_scores_gemma":[0.00062598963,0.0004888751,0.016771091,0.00021450584,0.000015415342,0.000019333258,0.00009956033,0.002189307,0.8873549,0.091394044,0.0006405165,0.00018642336],"about_ca_topic_score_codex":0.000008693541,"about_ca_topic_score_gemma":0.00000983073,"teacher_disagreement_score":0.050599214,"about_ca_system_score_codex":0.0000095538935,"about_ca_system_score_gemma":0.00003415614,"threshold_uncertainty_score":0.4765242},"labels":[],"label_agreement":null},{"id":"W4399586494","doi":"10.1038/s41398-024-02902-2","title":"Decoding the inflammatory signature of the major depressive episode: insights from peripheral immunophenotyping in active and remitted condition, a case–control study","year":2024,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Agencia Nacional de Promoción Científica y Tecnológica; Ministerio de Ciencia, Tecnología e Innovación Productiva; Consejo Nacional de Investigaciones Científicas y Técnicas; Brain and Behavior Research Foundation","keywords":"Monocytosis; FOXP3; Immunophenotyping; Medicine; Internal medicine; Major depressive episode; Immunology; Bipolar disorder; Immune system; Oncology; Flow cytometry; Lithium (medication); Bone marrow","score_opus":0.009014538591800176,"score_gpt":0.2518123668581063,"score_spread":0.24279782826630614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399586494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929748,0.0034955062,0.00021896996,0.0017327751,0.0005181684,0.0006871049,0.00014594615,0.000033471577,0.00019326639],"genre_scores_gemma":[0.9993589,0.0000056054264,0.00005192576,0.00042941843,0.000089219604,0.00003550824,0.0000029641099,0.000015955571,0.000010504278],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987511,0.00030206383,0.0002734707,0.00032188758,0.00022574088,0.00012575957],"domain_scores_gemma":[0.99904114,0.00066918717,0.00007368647,0.00017128767,0.0000212273,0.000023479886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007090588,0.0001439283,0.00013341194,0.00007417973,0.00025830072,0.000052738804,0.00018206936,0.000077062,0.00006804426],"category_scores_gemma":[0.00004804439,0.00009106365,0.00007345842,0.00032316765,0.0001603012,0.00022713249,0.000016950278,0.0004005386,0.0000015873386],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025872635,0.0014100091,0.25693023,0.0004181921,0.0010983008,0.00053291,0.12836513,0.0066239033,0.46539128,0.116732776,0.0006177891,0.019292226],"study_design_scores_gemma":[0.003609886,0.000047521167,0.9249286,0.00022592235,0.00009152183,0.00007071116,0.0036388757,0.0068334844,0.0030474665,0.057187956,0.00005749581,0.00026054875],"about_ca_topic_score_codex":0.000060309303,"about_ca_topic_score_gemma":0.0010010463,"teacher_disagreement_score":0.6679984,"about_ca_system_score_codex":0.000016139742,"about_ca_system_score_gemma":0.00010432035,"threshold_uncertainty_score":0.3713468},"labels":[],"label_agreement":null},{"id":"W4399707799","doi":"10.1007/s00406-024-01836-6","title":"Genetics of suicide ideation. A role for inflammation and neuroplasticity?","year":2024,"lang":"en","type":"article","venue":"European Archives of Psychiatry and Clinical Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Aalborg Universitetshospital; Aalborg Universitet","keywords":"Genome-wide association study; Genetic association; Psychology; Suicidal ideation; Single-nucleotide polymorphism; Clinical psychology; Bioinformatics; Biology; Medicine; Poison control; Genetics; Human factors and ergonomics; Genotype; Gene","score_opus":0.032911863326713114,"score_gpt":0.31972848400003734,"score_spread":0.28681662067332425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399707799","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98625183,0.00052783795,0.008630016,0.0006423388,0.00076585857,0.00024802613,0.000042791307,0.000051178995,0.002840133],"genre_scores_gemma":[0.99627936,0.0009641425,0.002214783,0.00030732082,0.00011529014,0.0000018724993,7.4816404e-7,0.000018151357,0.00009834364],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99835896,0.00027387182,0.00053586776,0.0005160562,0.00014817913,0.0001670868],"domain_scores_gemma":[0.99813217,0.0014515227,0.00012765953,0.00017227209,0.000010883635,0.00010549816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002852649,0.00011894759,0.00016434489,0.00010928708,0.00009901908,0.000057731086,0.00024585353,0.000018932165,0.0000023631499],"category_scores_gemma":[0.0012530487,0.00010354299,0.00009407773,0.00020318276,0.0009553215,0.00013278871,0.00013091361,0.0001408304,0.0000019124057],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019681979,0.00020732527,0.017621808,0.00045321006,0.000005067462,0.0000065193835,0.0003435661,0.00014094044,0.7843521,0.06408635,0.00006977048,0.1325165],"study_design_scores_gemma":[0.0016713428,0.0029971323,0.80108625,0.0004776653,0.000067421985,0.00005653911,0.00015266305,0.09312085,0.05267462,0.039872024,0.007322627,0.0005008578],"about_ca_topic_score_codex":8.506057e-7,"about_ca_topic_score_gemma":0.0000028170334,"teacher_disagreement_score":0.78346443,"about_ca_system_score_codex":6.289267e-7,"about_ca_system_score_gemma":0.000046754347,"threshold_uncertainty_score":0.42223606},"labels":[],"label_agreement":null},{"id":"W4399730570","doi":"10.21203/rs.3.rs-4457569/v1","title":"Interferon upregulation as the cause of Alzheimer’s disease","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; McGill University Health Centre","funders":"","keywords":"Downregulation and upregulation; Disease; Interferon; Alzheimer's disease; Medicine; Interferon γ; Immunology; Interferon gamma; Biology; Pathology; Cytokine","score_opus":0.149110725222452,"score_gpt":0.4274078032718489,"score_spread":0.2782970780493969,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399730570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9695491,0.0063683377,0.00001922134,0.010040353,0.0007887539,0.0023795897,0.00029333547,0.00019207098,0.010369236],"genre_scores_gemma":[0.9978031,0.00035359323,0.000005900572,0.00009904641,0.00015477456,0.00017276466,0.000023466158,0.000046046694,0.0013413434],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99643123,0.0008081161,0.00028901102,0.0007176077,0.0013202953,0.000433748],"domain_scores_gemma":[0.9979494,0.0005890671,0.000076195734,0.0010498358,0.00015565642,0.00017979427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007237026,0.00020413367,0.00019514054,0.00033678793,0.0001662026,0.00021630539,0.0008316266,0.00014633824,0.00035778983],"category_scores_gemma":[0.001516291,0.00014019269,0.00020926644,0.0005236404,0.00057741255,0.000055871496,0.00259591,0.0014367658,0.0005200036],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004555844,0.0028684852,0.002019758,0.019483756,0.0008104604,0.0015832193,0.028363563,0.007922061,0.20818444,0.4218092,0.15319741,0.14920181],"study_design_scores_gemma":[0.0009703163,0.0008611415,0.038992148,0.00600801,0.00022255088,0.000015826605,0.0021506269,0.015444233,0.3412237,0.5774281,0.015465707,0.001217673],"about_ca_topic_score_codex":0.00014415912,"about_ca_topic_score_gemma":0.000024062803,"teacher_disagreement_score":0.15561889,"about_ca_system_score_codex":0.00007221573,"about_ca_system_score_gemma":0.00051480654,"threshold_uncertainty_score":0.6683768},"labels":[],"label_agreement":null},{"id":"W4399873316","doi":"10.1093/cercor/bhae255","title":"Compensatory thickening of cortical thickness in early stage of schizophrenia","year":2024,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Hunan Provincial Innovation Foundation for Postgraduate; Fundamental Research Funds for Central Universities of the Central South University; National Key Research and Development Program of China; China Scholarship Council; National Natural Science Foundation of China","keywords":"Psychosis; Schizophrenia (object-oriented programming); Cortex (anatomy); Abnormality; Temporal cortex; Medicine; Drug-naïve; Internal medicine; Psychology; Pathology; Audiology; Neuroscience; Psychiatry; Drug","score_opus":0.025607936664931732,"score_gpt":0.2734438354830349,"score_spread":0.2478358988181032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399873316","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99615985,0.00017332165,0.00011533073,0.00006922121,0.0003323819,0.00015341076,0.000030299534,0.000078733916,0.0028874474],"genre_scores_gemma":[0.999265,0.000011734863,0.00012227384,0.00011801472,0.000024059402,0.0000039540955,0.0000014152088,0.000021562264,0.00043196048],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985633,0.00013591483,0.00038263644,0.0003539054,0.00031454986,0.00024972623],"domain_scores_gemma":[0.9992511,0.0003581943,0.00006905449,0.00023232348,0.000023783037,0.000065505315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018263476,0.00013490368,0.0002582468,0.00018510083,0.000035825553,0.000030950563,0.00027568903,0.000093860785,0.00026877804],"category_scores_gemma":[0.00024800483,0.00012224572,0.000092337374,0.0005315107,0.00036317736,0.00018079225,0.00009611675,0.00040874307,0.000050331128],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002177673,0.0001287108,0.017160634,0.0004805284,0.000008175658,0.00010180341,0.0015009622,0.000021893033,0.84642506,0.13150728,0.00010303381,0.0023441273],"study_design_scores_gemma":[0.0015039801,0.00030001727,0.68255585,0.0004484549,0.000013953501,0.000016436143,0.00054527784,0.003500247,0.30689815,0.0032085418,0.0005995531,0.00040951563],"about_ca_topic_score_codex":0.000079583326,"about_ca_topic_score_gemma":0.00005008787,"teacher_disagreement_score":0.66539526,"about_ca_system_score_codex":0.000019058089,"about_ca_system_score_gemma":0.0001279857,"threshold_uncertainty_score":0.49850357},"labels":[],"label_agreement":null},{"id":"W4399883347","doi":"10.21203/rs.3.rs-4149042/v1","title":"Npbwr1 signaling mediates fast antidepressant action","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"","keywords":"Antidepressant; Nucleus accumbens; Depression (economics); Major depressive disorder; Chronic stress; Biomarker; Mood; Antagonist; Medicine; Regulator; Psychology; Internal medicine; Neuroscience; Psychiatry; Receptor; Hippocampus; Biology; Gene","score_opus":0.13627152306577522,"score_gpt":0.4190861122434898,"score_spread":0.28281458917771457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399883347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9714275,0.003499937,0.00010223115,0.0025668498,0.0020520205,0.001609301,0.00032765037,0.0007986075,0.017615898],"genre_scores_gemma":[0.995297,0.0017335799,0.000054662134,0.00008361064,0.000660471,0.00019666935,0.000039259576,0.000091861606,0.001842889],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9946773,0.0007878453,0.0003448116,0.0013632029,0.0018913143,0.0009355355],"domain_scores_gemma":[0.99759597,0.0011542698,0.00007917937,0.000747152,0.00017864603,0.00024477302],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010830273,0.0003322116,0.00032874275,0.00079465355,0.0003458077,0.0007281893,0.00089949224,0.000392453,0.0005658156],"category_scores_gemma":[0.0020172205,0.00029268465,0.00024808914,0.0008337779,0.00037489005,0.000111539855,0.0027139564,0.0034271213,0.0014331233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012461061,0.00029932533,0.00034198933,0.0053641866,0.000046216046,0.00049589307,0.0017318464,0.0012871019,0.93578225,0.0044165673,0.017663172,0.03244684],"study_design_scores_gemma":[0.0003590603,0.00014636794,0.0010444705,0.0020189933,0.000013858494,0.000012889844,0.0014783102,0.004633194,0.9224621,0.055463348,0.011716838,0.00065056916],"about_ca_topic_score_codex":0.00017125942,"about_ca_topic_score_gemma":0.000041257303,"teacher_disagreement_score":0.05104678,"about_ca_system_score_codex":0.00017167389,"about_ca_system_score_gemma":0.00042103918,"threshold_uncertainty_score":0.99995255},"labels":[],"label_agreement":null},{"id":"W4399924939","doi":"10.1016/j.schres.2024.06.020","title":"Clozapine treatment and astrocyte activity in treatment resistant schizophrenia: A proton magnetic resonance spectroscopy study","year":2024,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Ontario Mental Health Foundation","keywords":"Clozapine; Schizophrenia (object-oriented programming); Antipsychotic; Dorsolateral prefrontal cortex; Striatum; Psychology; Internal medicine; Ventral striatum; Anterior cingulate cortex; Medicine; Atypical antipsychotic; Neuroscience; Pharmacology; Psychiatry; Prefrontal cortex; Dopamine; Cognition","score_opus":0.06275641152693813,"score_gpt":0.362656632827876,"score_spread":0.2999002213009379,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399924939","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841006,0.009133491,0.0000039953857,0.0010013689,0.00013623819,0.0046311654,0.000063624255,0.00021681073,0.00071274955],"genre_scores_gemma":[0.9921,0.0035059017,0.0003462475,0.000013838985,0.00017231422,0.0018838518,0.0000024658564,0.000072810275,0.0019025938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99462086,0.0011807622,0.00038693112,0.0017414279,0.00089657714,0.0011734695],"domain_scores_gemma":[0.9981707,0.0006822744,0.000036772057,0.00078070693,0.00004309432,0.00028646112],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007662049,0.00048690898,0.0004972806,0.00093266944,0.00042482273,0.0005262387,0.00039124928,0.000121465135,0.00014517018],"category_scores_gemma":[0.00027342763,0.0003751285,0.000112204536,0.001980019,0.00047310544,0.00030173495,0.00022998748,0.0006935138,0.00018880941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.025267445,0.0034719373,0.0014592081,0.00014981146,0.0000275286,0.0015850659,0.0018179698,0.0000043205673,0.64186925,0.001957937,0.00013885715,0.32225066],"study_design_scores_gemma":[0.027137578,0.034729023,0.097481176,0.0004986412,0.000039370596,0.00008266905,0.00087342603,0.0022641716,0.79827297,0.004059861,0.033468038,0.0010930941],"about_ca_topic_score_codex":0.0007886593,"about_ca_topic_score_gemma":0.0027576566,"teacher_disagreement_score":0.32115757,"about_ca_system_score_codex":0.000946929,"about_ca_system_score_gemma":0.00062429905,"threshold_uncertainty_score":0.99987006},"labels":[],"label_agreement":null},{"id":"W4400010615","doi":"10.20944/preprints202406.1588.v1","title":"The Interplay Between Multisystem Inflammatory Syndrome in Children, Interleukin 6, Microbiome, and Gut Barrier Integrity","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Metabolomics Innovation Centre","funders":"","keywords":"Microbiome; Gut microbiome; Immunology; Medicine; Interleukin; Biology; Cytokine; Bioinformatics","score_opus":0.0470142113221586,"score_gpt":0.324442313420214,"score_spread":0.2774281020980554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400010615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942629,0.0005964521,0.0000119249835,0.0005803152,0.0011855791,0.0016054919,0.0002021176,0.0003286755,0.0012265482],"genre_scores_gemma":[0.99785316,0.00022399107,0.000019830657,0.00016041716,0.00011804333,0.00025224432,0.000018446708,0.00009854428,0.0012552944],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99503696,0.0006905334,0.0011168577,0.0020416596,0.00039380376,0.000720172],"domain_scores_gemma":[0.9972463,0.0005881169,0.0003401306,0.0015467065,0.00004807546,0.00023063566],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001323442,0.00071383436,0.0007172809,0.0005112454,0.00021257754,0.0002692319,0.0018305905,0.0006387342,0.00011556125],"category_scores_gemma":[0.0011155069,0.0005701308,0.00029132076,0.00036860566,0.0006955009,0.00013817869,0.007934754,0.003860234,0.001358193],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058185484,0.00007692247,0.9226169,0.0005889237,0.00014732583,0.00013034069,0.0022321718,0.000010348173,0.07094944,0.0008063998,0.00012326938,0.0022597834],"study_design_scores_gemma":[0.0006193997,0.000025967714,0.92144585,0.0014497798,0.00004003844,0.00024392022,0.00023825062,0.00008835739,0.06890233,0.004536459,0.0016232324,0.00078641524],"about_ca_topic_score_codex":0.00025609083,"about_ca_topic_score_gemma":0.00017320247,"teacher_disagreement_score":0.0061041634,"about_ca_system_score_codex":0.00029409162,"about_ca_system_score_gemma":0.00021706002,"threshold_uncertainty_score":0.99967504},"labels":[],"label_agreement":null},{"id":"W4400026233","doi":"10.17615/t1ae-0545","title":"Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression","year":2024,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cilag; National Institute of Mental Health; National Health and Medical Research Council; Stanley Center for Psychiatric Research, Broad Institute; University of North Carolina at Chapel Hill; School of Medicine, Emory University; National Institutes of Health; Centre for Cognitive Ageing and Cognitive Epidemiology; H. Lundbeck A/S; Medical Research Council; Siemens Healthineers; Innovative Medicines Initiative; Chinese Society of Clinical Oncology; Rheinische Friedrich-Wilhelms-Universität Bonn; Universitair Medisch Centrum Groningen; Dokuz Eylül Üniversitesi; Vetenskapsrådet; GGZ Drenthe; Pfizer; Rivierduinen; GGZ inGeest; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Bundesministerium für Bildung und Forschung; Erasmus Medisch Centrum; Vrije Universiteit Amsterdam; Karolinska Institutet; ZonMw; King's College London; Max-Planck-Gesellschaft; Rijksuniversiteit Groningen; Universiteit Leiden; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Cancer Institute; University College London; Lundbeckfonden; Kaiser Permanente; Cardiff University; Universität Greifswald; GGZ Friesland; Philipps-Universität Marburg; Aarhus Universitet; Universität Basel; QIMR Berghofer Medical Research Institute; Højteknologifonden; Leids Universitair Medisch Centrum; Department of Health and Social Care; National Institute for Health and Care Research; Aarhus Universitetshospital; University of Southern California; Foundation for the National Institutes of Health; Broad Institute; Wellcome Trust; Westfälische Wilhelms-Universität Münster; Emory University; National Science Foundation; Massachusetts General Hospital; Dalhousie University; GlaxoSmithKline; AstraZeneca; University of Worcester","keywords":"Haplotype; Allele; Genetics; Depression (economics); Biology; Immunology; Gene","score_opus":0.0348826973810497,"score_gpt":0.24256077520818722,"score_spread":0.2076780778271375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400026233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943482,0.0007336673,0.00010947375,0.0015033291,0.00010704666,0.00016572648,0.00002947084,0.0006531377,0.002349923],"genre_scores_gemma":[0.99714696,0.000023221786,0.00017710833,0.00063814566,0.00006288617,0.000010106731,0.000011180316,0.00004013115,0.0018902338],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868995,0.000097740754,0.00014896369,0.0005106636,0.0002721382,0.00028055647],"domain_scores_gemma":[0.99926615,0.00041165552,0.00005376454,0.00016127477,0.000011864919,0.00009527623],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057031768,0.00019194554,0.0001939406,0.000096438984,0.00031075068,0.00058068044,0.00019018124,0.00010299285,0.000066248256],"category_scores_gemma":[0.0002427337,0.00013532588,0.000041281153,0.0002614381,0.00047778702,0.000647299,0.000109410794,0.00020801809,0.000025256999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030743724,0.0002951468,0.030152982,0.00015627897,0.000088168854,0.0005315723,0.0022912947,0.00002151851,0.5995126,0.34343976,0.019856926,0.0033463216],"study_design_scores_gemma":[0.0008300725,0.00025249846,0.17761666,0.00041387544,0.000026109243,0.000013325868,0.0004842093,0.00078851107,0.7787371,0.025934404,0.014326292,0.0005769067],"about_ca_topic_score_codex":0.000007710906,"about_ca_topic_score_gemma":0.000051217343,"teacher_disagreement_score":0.31750536,"about_ca_system_score_codex":0.000011720698,"about_ca_system_score_gemma":0.00007056287,"threshold_uncertainty_score":0.5599515},"labels":[],"label_agreement":null},{"id":"W4400070154","doi":"10.1101/2024.06.26.24308831","title":"Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Medical Research Council; Fonds de Recherche du Québec - Santé; McGill University","keywords":"Glutamate receptor; Neurochemical; Glutathione; Internal medicine; Antipsychotic; Psychosis; Schizophrenia (object-oriented programming); Endocrinology; Glutamine; Medicine; Posterior cingulate; Psychology; Cortex (anatomy); Psychiatry; Neuroscience; Chemistry; Receptor; Biochemistry; Amino acid","score_opus":0.027314864724229487,"score_gpt":0.28327018782872576,"score_spread":0.25595532310449626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400070154","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98791146,0.0085774185,0.000006813303,0.0022435642,0.00040609558,0.00025832176,0.000025300455,0.000039929746,0.000531108],"genre_scores_gemma":[0.99694324,0.0024818352,0.000013804732,0.0004191826,0.000018916973,0.0000582582,9.320222e-7,0.000013505274,0.00005033877],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99861324,0.00016159475,0.00022367049,0.0006430551,0.00014463914,0.00021381753],"domain_scores_gemma":[0.9993405,0.00040155934,0.000054194574,0.00014331948,0.000006737401,0.000053722055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002836146,0.00018370493,0.0002036588,0.000113533344,0.00007498412,0.00016074436,0.00012246115,0.00011233585,0.000008400803],"category_scores_gemma":[0.0004111142,0.0001302913,0.00002042162,0.00022578225,0.00040209029,0.00005296925,0.0002931022,0.00066555646,0.00000813441],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003464423,0.0001611432,0.6881143,0.0015653762,0.0000291974,0.00032590004,0.0057659266,0.00007157214,0.0729069,0.2172496,0.0002760358,0.013187602],"study_design_scores_gemma":[0.0006451617,0.00007997817,0.94273317,0.00074945285,0.000026756456,0.00006379638,0.0003356914,0.0048475983,0.006908056,0.04174634,0.0014243138,0.0004396912],"about_ca_topic_score_codex":0.00006468899,"about_ca_topic_score_gemma":0.0003770829,"teacher_disagreement_score":0.25461885,"about_ca_system_score_codex":0.000021612135,"about_ca_system_score_gemma":0.000034165125,"threshold_uncertainty_score":0.53131247},"labels":[],"label_agreement":null},{"id":"W4400093376","doi":"10.1002/alz.14034","title":"The ketamine metabolite ( <i>2R,6R</i> )‐hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease","year":2024,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Carleton University; Queen's University; Centre for Research on Brain Language and Music; McGill University","funders":"National Institutes of Health; Instituto Nacional de Ciência e Tecnologia de Neurociência Translacional; Instituto Serrapilheira; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Alzheimer's Society; Conselho Nacional de Desenvolvimento Científico e Tecnológico; International Brain Research Organization; American Society for Biochemistry and Molecular Biology; National Institute of Neurological Disorders and Stroke; International Society for Neurochemistry; Alzheimer's Association","keywords":"Long-term potentiation; Synaptic plasticity; Hippocampal formation; Neuroscience; PI3K/AKT/mTOR pathway; Hippocampus; Biology; MAPK/ERK pathway; Signal transduction; P70-S6 Kinase 1; Cell biology; Biochemistry; Receptor","score_opus":0.03231858194955664,"score_gpt":0.2567476594721636,"score_spread":0.22442907752260696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400093376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.49993926,0.49536794,0.0008300764,0.0012030118,0.00045685942,0.0009396812,0.00017177532,0.0002094317,0.00088195654],"genre_scores_gemma":[0.9970061,0.0023503506,0.00018485032,0.00025765903,0.000055369637,0.000063439045,0.000012486385,0.000049614115,0.000020087205],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974146,0.00030007906,0.0006303502,0.0006804277,0.00047319153,0.00050134724],"domain_scores_gemma":[0.99858797,0.0006927351,0.00010359474,0.0003763299,0.000042634798,0.0001967151],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004044496,0.00032865425,0.0003300619,0.00020167197,0.00020671262,0.00015458908,0.0003715272,0.00007285534,0.000039653787],"category_scores_gemma":[0.00014042502,0.00025184167,0.00013178622,0.00061545096,0.000508674,0.00056286046,0.00011373735,0.00025162703,0.000016715932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015948339,0.0014310781,0.0013865605,0.00028949286,0.01342395,0.00032562055,0.0058164224,0.01094436,0.49556476,0.040740136,0.0022003937,0.4262824],"study_design_scores_gemma":[0.0040680063,0.0003003341,0.011147297,0.00025000135,0.018581469,0.000029503195,0.0004897325,0.37896577,0.5539975,0.020900143,0.009469323,0.0018009319],"about_ca_topic_score_codex":0.000065897504,"about_ca_topic_score_gemma":0.00007293677,"teacher_disagreement_score":0.4970669,"about_ca_system_score_codex":0.000004152685,"about_ca_system_score_gemma":0.000094483235,"threshold_uncertainty_score":0.9999934},"labels":[],"label_agreement":null},{"id":"W4400106001","doi":"10.1016/j.jad.2024.06.092","title":"Exosome-associated mitochondrial DNA in late-life depression: Implications for cognitive decline in older adults","year":2024,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; National Institutes of Health; Ontario Ministry of Health and Long-Term Care; Ontario Ministry of Research and Innovation; BrightFocus Foundation; Fondation Brain Canada; University of Saskatchewan; Weston Brain Institute; Biogen","keywords":"Mitochondrial DNA; Depression (economics); Mitochondrion; Microvesicles; Biology; Tumor necrosis factor alpha; Medicine; Gerontology; Immunology; Cell biology; microRNA; Genetics","score_opus":0.014002705132221209,"score_gpt":0.29857544955286885,"score_spread":0.28457274442064767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400106001","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933068,0.0006939016,0.0014633837,0.0024234038,0.00071662327,0.00095477595,0.000060635495,0.00003352981,0.00034692543],"genre_scores_gemma":[0.99883986,0.00022444554,0.00004405988,0.00061775936,0.00009592677,0.00009944789,0.0000067090464,0.000034957426,0.000036852278],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99830467,0.00022855148,0.0005030306,0.00038639008,0.00022697716,0.00035037007],"domain_scores_gemma":[0.9971117,0.002344128,0.0002209871,0.00009495096,0.00011201832,0.000116234885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025982017,0.00020159566,0.00032818268,0.00055187213,0.00007812788,0.000074268035,0.00023961498,0.00013874401,0.000029592069],"category_scores_gemma":[0.0051108054,0.00017515667,0.00022345565,0.0010557257,0.00011573143,0.00041235535,0.000051271472,0.00041987136,0.0000070868864],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01171552,0.011751481,0.27740383,0.0007517223,0.00042790335,0.00026244906,0.025502,0.002817012,0.24118674,0.003306322,0.010919623,0.4139554],"study_design_scores_gemma":[0.014248671,0.00048669978,0.9588336,0.0013084824,0.00003621262,0.000012034338,0.0013262692,0.0013283897,0.007897544,0.013780436,0.00034187423,0.00039982056],"about_ca_topic_score_codex":0.000044370514,"about_ca_topic_score_gemma":0.0019166435,"teacher_disagreement_score":0.68142974,"about_ca_system_score_codex":0.00012081631,"about_ca_system_score_gemma":0.00021880679,"threshold_uncertainty_score":0.71426815},"labels":[],"label_agreement":null},{"id":"W4400148970","doi":"10.1016/j.cdnut.2024.103179","title":"Dietary Vitamin B6 Deficiency and Gut Microbiota Depletion Can Lead to Anxiety-Like Behavior in Rats","year":2024,"lang":"en","type":"article","venue":"Current Developments in Nutrition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Vitamin b6; Anxiety; Vitamin; Gut flora; Lead (geology); Biology; Physiology; Medicine; Endocrinology; Immunology; Psychiatry","score_opus":0.03446004403236965,"score_gpt":0.2951842819988754,"score_spread":0.2607242379665058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400148970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957814,0.0016326113,0.000034901437,0.00031532947,0.0012363411,0.0007892286,0.000045268305,0.00007536588,0.00008954143],"genre_scores_gemma":[0.9969033,0.00197815,0.00048441326,0.00022887049,0.000025214165,0.00025417554,0.00005983009,0.000019231627,0.000046785543],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99838305,0.000077289355,0.00032227533,0.0006439794,0.00020622,0.00036717657],"domain_scores_gemma":[0.99971956,0.000047551024,0.000027214744,0.00011541026,0.000015334159,0.00007490673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013894172,0.00019346888,0.00014718238,0.00056124415,0.00008076269,0.000105844076,0.00015805407,0.00007495058,0.000011967121],"category_scores_gemma":[0.00006529898,0.00020799461,0.000029861343,0.0009416449,0.000060940773,0.00021003536,0.0000941021,0.0002324825,0.000047769692],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038445316,0.00083170575,0.017433621,0.00050893606,0.0000011232286,0.00004817766,0.0012469047,0.000002172138,0.78864324,0.00010442722,0.0022072762,0.18893397],"study_design_scores_gemma":[0.0024304977,0.00016489328,0.8130081,0.0029591925,0.000014292211,0.000083410276,0.00042573974,0.00017699425,0.1414831,0.0006361694,0.03742283,0.0011947694],"about_ca_topic_score_codex":0.000021061089,"about_ca_topic_score_gemma":0.00025644855,"teacher_disagreement_score":0.7955745,"about_ca_system_score_codex":0.00022044708,"about_ca_system_score_gemma":0.00007348052,"threshold_uncertainty_score":0.84817743},"labels":[],"label_agreement":null},{"id":"W4400684482","doi":"10.1007/s00406-024-01864-2","title":"Activation of the interleukin-23/Th17 axis in major depression: a systematic review and meta-analysis","year":2024,"lang":"en","type":"review","venue":"European Archives of Psychiatry and Clinical Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"NIHR Imperial Biomedical Research Centre; NIHR Maudsley Biomedical Research Centre; King's College London; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research","keywords":"Meta-analysis; Medicine; Depression (economics); Internal medicine; Strictly standardized mean difference; Interleukin 17; Interleukin; Cytokine; Gastroenterology; Immunology","score_opus":0.10617517466146903,"score_gpt":0.38735610825295735,"score_spread":0.2811809335914883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400684482","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011165851,0.99658114,0.000041374537,0.0004617246,0.00029407642,0.0013235685,0.00007072864,0.000020287696,0.0010954736],"genre_scores_gemma":[0.0034335991,0.9945834,0.00009264727,0.0013199956,0.00001979908,0.000024918218,0.0000012915411,0.000030348392,0.00049396337],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9922234,0.003929262,0.0021325732,0.0011427834,0.00034798193,0.00022400827],"domain_scores_gemma":[0.9960602,0.0016258439,0.0012545637,0.0009353876,0.000010049627,0.00011393889],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011424037,0.000402231,0.0033307858,0.0003224721,0.000094640105,0.000059832495,0.0012832492,0.00005684762,0.000010969719],"category_scores_gemma":[0.0025275738,0.00020673321,0.002117766,0.0016814414,0.0011641303,0.0001123882,0.0007598104,0.00069850765,0.000005759664],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001857956,0.00050161185,0.00010067186,0.9862431,0.0024455641,0.0000134017055,0.00013091526,0.000001533123,0.00005661336,0.0015409713,0.0001375321,0.008809481],"study_design_scores_gemma":[0.0007269332,0.0006277891,0.0032995827,0.26393145,0.71287197,0.00015491295,0.00008213225,0.00017478195,0.00004274049,0.0017373802,0.0149351265,0.0014152172],"about_ca_topic_score_codex":0.0000020364116,"about_ca_topic_score_gemma":0.000008253637,"teacher_disagreement_score":0.7223117,"about_ca_system_score_codex":0.0000029760156,"about_ca_system_score_gemma":0.00009217829,"threshold_uncertainty_score":0.84303355},"labels":[],"label_agreement":null},{"id":"W4400698135","doi":"10.1038/s41398-024-03010-x","title":"Prenatal immune activation in mice induces long-term alterations in brain mitochondrial function","year":2024,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Offspring; Mitochondrial biogenesis; Mitochondrion; Biology; Endocrinology; Internal medicine; Mitochondrial respiratory chain; Superoxide dismutase; Prefrontal cortex; Andrology; Cell biology; Pregnancy; Medicine; Oxidative stress; Neuroscience; Genetics","score_opus":0.020821594995590012,"score_gpt":0.28107320692809146,"score_spread":0.26025161193250146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400698135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98104596,0.00035486213,0.0044084373,0.010308401,0.002260843,0.00039549265,0.000024969928,0.000101972575,0.0010990308],"genre_scores_gemma":[0.9984895,0.0000071404443,0.00024377837,0.00056379265,0.00035789807,0.000045206285,0.00009237979,0.00001982238,0.00018047652],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99866205,0.000102225495,0.0003516154,0.00042241882,0.00026025507,0.00020140762],"domain_scores_gemma":[0.999561,0.0002589085,0.0000357056,0.00010109379,0.000009883976,0.000033403285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009345706,0.00014496081,0.00010527369,0.00040129316,0.00007454932,0.000105811574,0.00012734727,0.00010872692,0.0002109975],"category_scores_gemma":[0.000047272304,0.00015108363,0.00007411555,0.0007392983,0.000046637,0.00075654715,0.000007579032,0.0003154782,0.000060565613],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00079385715,0.00068313413,0.00672869,0.00030814714,0.000019650957,0.000008759044,0.0020195183,0.0026631046,0.91539174,0.060608447,0.00077161816,0.010003334],"study_design_scores_gemma":[0.0034681547,0.00012667077,0.91260016,0.0007690609,0.000011722299,0.000016122038,0.00011157753,0.0037048894,0.042417932,0.035911452,0.00030079813,0.0005614644],"about_ca_topic_score_codex":0.000032157684,"about_ca_topic_score_gemma":0.0005288558,"teacher_disagreement_score":0.90587145,"about_ca_system_score_codex":0.000031523083,"about_ca_system_score_gemma":0.00017919262,"threshold_uncertainty_score":0.61610115},"labels":[],"label_agreement":null},{"id":"W4400779734","doi":"10.1016/j.intimp.2024.112649","title":"Corrigendum to “Thiadiazine-thione derivatives ameliorate STZ-induced diabetic neuropathy by regulating insulin and neuroinflammatory signaling” [Int. Immunopharmacol. 113 (2022) 109421]","year":2024,"lang":"en","type":"erratum","venue":"International Immunopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University Health Network","funders":"","keywords":"Medicine; Insulin; Insulin receptor; Pharmacology; Internal medicine; Insulin resistance","score_opus":0.02341350092479315,"score_gpt":0.2909500500645402,"score_spread":0.26753654913974706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400779734","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.76760787,0.014316683,0.00004461454,0.0062010796,0.2013487,0.0022005728,0.0009804145,0.00085362815,0.0064464025],"genre_scores_gemma":[0.7617241,0.012657167,0.00012650328,0.022119656,0.004555208,0.0010060682,0.0006279101,0.0008261191,0.19635724],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99297035,0.00096867286,0.0015121405,0.002262401,0.0011092162,0.0011772474],"domain_scores_gemma":[0.99723047,0.00061547273,0.0008013265,0.0005621266,0.00035709713,0.0004334838],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005322013,0.0012298174,0.0010402716,0.0012335726,0.00047884777,0.00058628904,0.001998383,0.00067597243,0.0017070787],"category_scores_gemma":[0.0011854098,0.0013306916,0.0003125339,0.0010734177,0.0004959492,0.0005023397,0.0014867804,0.003565337,0.0011907856],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025764707,0.0001433318,0.000006085287,0.00010471995,0.00015201049,0.00035816676,0.00044131486,0.000018377868,0.6110637,0.00012993928,0.38379684,0.0035278504],"study_design_scores_gemma":[0.002237526,0.00053076504,0.0004013379,0.00032739967,0.00015274862,0.00014311948,0.0001369909,0.002446222,0.37708288,0.00044358804,0.6146402,0.0014572501],"about_ca_topic_score_codex":0.000066046035,"about_ca_topic_score_gemma":0.0000062471568,"teacher_disagreement_score":0.23398082,"about_ca_system_score_codex":0.0003726875,"about_ca_system_score_gemma":0.00054328324,"threshold_uncertainty_score":0.9995869},"labels":[],"label_agreement":null},{"id":"W4400998146","doi":"10.1186/s12885-022-10427-4","title":"Pembrolizumab with platinum-based chemotherapy with or without epacadostat as first-line treatment for metastatic non-small cell lung cancer: a randomized, partially double-blind, placebo-controlled phase II study","year":2024,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre intégré de santé et de services sociaux de la Montérégie-Centre; Santé Montérégie","funders":"Incyte","keywords":"Medicine; Surgical oncology; Pembrolizumab; Chemotherapy; Placebo; Oncology; Internal medicine; Lung cancer; Cancer; Immunotherapy; Pathology","score_opus":0.04983675772780816,"score_gpt":0.35522853128661147,"score_spread":0.3053917735588033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400998146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9563207,0.0013471595,0.015890975,0.00077415386,0.00029653675,0.024563108,0.00023533501,0.00027496272,0.000297059],"genre_scores_gemma":[0.9589385,0.00032421926,0.0010161938,0.0006657725,0.00019432361,0.03176119,0.000016705018,0.00018500081,0.0068981014],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9965231,0.00021352895,0.00065888785,0.0012539139,0.0005691925,0.00078136555],"domain_scores_gemma":[0.9973349,0.0015009008,0.00033393383,0.00047559422,0.00010256028,0.00025211505],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037035652,0.0007898439,0.0016389043,0.00025224753,0.00043548553,0.00028307983,0.00031767547,0.00007906396,0.0006276213],"category_scores_gemma":[0.000057891364,0.00043519854,0.00036403304,0.0006283575,0.0002175561,0.0002018683,0.000027465494,0.00019773091,0.000008983494],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.968878,0.0028094372,0.0002570194,0.00043516955,0.0006559373,0.00009415615,0.00426232,0.018810162,0.001168683,0.000026440457,0.00019470099,0.002407997],"study_design_scores_gemma":[0.81851846,0.0086967265,0.0000028535055,0.00029521208,0.0012731763,0.000010749699,0.00033283967,0.1390392,0.030234225,0.000011909814,0.00100569,0.0005789344],"about_ca_topic_score_codex":0.0014765152,"about_ca_topic_score_gemma":0.028248541,"teacher_disagreement_score":0.1503595,"about_ca_system_score_codex":0.00038056873,"about_ca_system_score_gemma":0.0027242429,"threshold_uncertainty_score":0.99981},"labels":[],"label_agreement":null},{"id":"W4400998846","doi":"10.1186/s12885-023-11316-0","title":"Pembrolizumab plus epacadostat in patients with recurrent/metastatic head and neck squamous cell carcinoma (KEYNOTE-669/ECHO-304): a phase 3, randomized, open-label study","year":2024,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital; Hôtel-Dieu de Québec","funders":"Merck Sharp and Dohme; Astellas Pharma; Eisai; Incyte; Amgen; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; GlaxoSmithKline","keywords":"Pembrolizumab; Medicine; Tolerability; Head and neck squamous-cell carcinoma; Oncology; Clinical endpoint; Internal medicine; Regimen; Phases of clinical research; Clinical trial; Ipilimumab; Adverse effect; Head and neck cancer; Immunotherapy; Cancer","score_opus":0.04522785211261003,"score_gpt":0.3353546691208892,"score_spread":0.29012681700827914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400998846","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912792,0.0026664545,0.00007608254,0.00007305555,0.00048115072,0.0044680354,0.0001758972,0.00007866176,0.00070148427],"genre_scores_gemma":[0.99805146,0.00007792353,0.00014661369,0.00030831562,0.00003380562,0.0006958225,0.000010711505,0.0000679741,0.000607363],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99697423,0.00047310712,0.00047580528,0.0010255207,0.0004984394,0.00055291736],"domain_scores_gemma":[0.9987362,0.0005573075,0.00012378629,0.00035728564,0.000040993622,0.00018439634],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027648956,0.00039654845,0.0006972377,0.0002271123,0.00013934918,0.0003856033,0.000426912,0.0000523619,0.00013754773],"category_scores_gemma":[0.00022396412,0.00030278857,0.000058874866,0.0007876587,0.00021406158,0.00047831718,0.00023123308,0.00035273866,0.000033357454],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.7896433,0.029885255,0.072175376,0.0026531436,0.00011069823,0.0009769175,0.030364025,0.00045232713,0.0019682301,0.0006573992,0.0054021096,0.06571124],"study_design_scores_gemma":[0.97639686,0.0028034088,0.009499449,0.00023139018,0.00013399363,0.0000078598805,0.00066648464,0.007910368,0.0008670107,0.00020339379,0.00053720275,0.0007425621],"about_ca_topic_score_codex":0.0010946074,"about_ca_topic_score_gemma":0.002070354,"teacher_disagreement_score":0.18675359,"about_ca_system_score_codex":0.0002149692,"about_ca_system_score_gemma":0.00045641078,"threshold_uncertainty_score":0.9999424},"labels":[],"label_agreement":null},{"id":"W4401147819","doi":"10.1016/j.bbi.2024.07.037","title":"Sex differences in the inflammation-depression link: A systematic review and meta-analysis","year":2024,"lang":"en","type":"review","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Carleton University","funders":"","keywords":"Depression (economics); Meta-analysis; PsycINFO; Internal medicine; Major depressive disorder; Medicine; Inflammation; Tumor necrosis factor alpha; Clinical psychology; Psychology; MEDLINE; Biology","score_opus":0.1478163369819221,"score_gpt":0.37109695760243644,"score_spread":0.22328062062051435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401147819","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022168586,0.9963733,0.0000019270046,0.00034880653,0.000023472183,0.0028083536,0.000083087354,0.00003726908,0.00010207922],"genre_scores_gemma":[0.0019346791,0.99540854,0.000004315381,0.00045281093,0.000010437148,0.001439516,0.000027914402,0.000020992662,0.0007007949],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99513155,0.0029490758,0.000887617,0.0005037959,0.0003178165,0.00021012453],"domain_scores_gemma":[0.9972533,0.001553231,0.0003426194,0.0007809001,0.000015705584,0.000054237073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013168061,0.00046282678,0.00382281,0.00035007182,0.00020830616,0.00029383236,0.0006241059,0.00018278854,0.00007962164],"category_scores_gemma":[0.0008069065,0.00021743623,0.0009894274,0.0012698199,0.00015956946,0.00012521727,0.00023308182,0.00073105085,0.00001709946],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[7.760134e-7,0.00008895609,0.000010485616,0.9715411,0.0038465436,0.000033366952,0.00088363624,1.3001314e-8,0.00000887543,0.00017287066,0.00015245416,0.023260893],"study_design_scores_gemma":[0.00009136821,0.000033175504,0.00019993403,0.028529832,0.96234655,0.000104957035,0.00020942983,0.0000035925596,0.0000042822153,0.00009081344,0.007838362,0.0005476833],"about_ca_topic_score_codex":0.000053578413,"about_ca_topic_score_gemma":0.00003202499,"teacher_disagreement_score":0.9585,"about_ca_system_score_codex":0.00001523492,"about_ca_system_score_gemma":0.00004215386,"threshold_uncertainty_score":0.88667923},"labels":[],"label_agreement":null},{"id":"W4401302597","doi":"10.1016/j.bbih.2024.100832","title":"Maternal immune response during pregnancy and neurodevelopmental outcomes: A longitudinal approach","year":2024,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Grand Challenges Canada; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação Maria Cecilia Souto Vidigal; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Pregnancy; Offspring; Psychosocial; Gestation; Anxiety; Medicine; Immune system; Obstetrics; Psychology; Immunology; Psychiatry; Biology","score_opus":0.05351011170222243,"score_gpt":0.3249066592722431,"score_spread":0.2713965475700207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401302597","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994593,0.0014790918,0.000048482,0.0020207772,0.0004070812,0.0008103235,0.00006628339,0.00043466248,0.00014027349],"genre_scores_gemma":[0.9967592,0.00023928998,0.00040150303,0.0005032353,0.000016970282,0.00013530653,0.000011860552,0.00006985561,0.0018628171],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9967547,0.0008172091,0.0005567345,0.0007206126,0.00041057394,0.0007401472],"domain_scores_gemma":[0.99873304,0.00038328633,0.00010941742,0.000514374,0.000015241433,0.0002446458],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00054848153,0.00036412882,0.00038317076,0.00032838262,0.00075880747,0.00030657824,0.00044838642,0.000093963485,0.00008074384],"category_scores_gemma":[0.00028165034,0.0003385097,0.00012331981,0.00048522046,0.000257854,0.00039848711,0.0003586946,0.00069421524,0.000049604096],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012176423,0.0019427331,0.11534792,0.0021188657,0.00004310096,0.0015731992,0.013233467,0.0000043288546,0.8058675,0.0012695607,0.0003124192,0.05706927],"study_design_scores_gemma":[0.00085595716,0.0001701734,0.9903325,0.0003479298,0.000007755083,0.00082231226,0.00037562093,0.000031336633,0.00644727,0.000022750293,0.00026536197,0.00032105396],"about_ca_topic_score_codex":0.00045263168,"about_ca_topic_score_gemma":0.000016553073,"teacher_disagreement_score":0.87498456,"about_ca_system_score_codex":0.00019098198,"about_ca_system_score_gemma":0.0003109596,"threshold_uncertainty_score":0.9999067},"labels":[],"label_agreement":null},{"id":"W4401366910","doi":"10.21203/rs.3.rs-4486754/v1","title":"Chronic gut inflammation differentially modulates mitochondrial and antioxidant transcriptional programs in limbic brain structures","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Inflammation; Nucleus accumbens; Neuroscience; Biology; Limbic system; Hippocampus; Central nervous system; Immunology","score_opus":0.0651927524763352,"score_gpt":0.34569474811201784,"score_spread":0.2805019956356826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401366910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911314,0.0020954693,0.000049093247,0.0033956678,0.0006816298,0.0021698764,0.00010228027,0.00016112825,0.00021341792],"genre_scores_gemma":[0.99765104,0.0004773497,0.00009721661,0.000018661642,0.0008746798,0.0003195574,0.00010677826,0.00005923378,0.00039548028],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9955162,0.0007321248,0.00045260316,0.001211147,0.0013177592,0.00077018427],"domain_scores_gemma":[0.9989086,0.0003439357,0.000069060945,0.00042043126,0.00009814779,0.00015982574],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004099799,0.0003591274,0.00034844462,0.0008687105,0.0001839276,0.0008387378,0.00051943614,0.0004221507,0.00013551475],"category_scores_gemma":[0.00057380623,0.0003200119,0.00016814828,0.00058227225,0.00048496728,0.00014627351,0.0008177458,0.0021459837,0.000038083876],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001342306,0.000093745926,0.00018982496,0.0023462076,0.000019581643,0.000083885665,0.001297306,0.00039076136,0.93445873,0.016757987,0.00020364184,0.04402407],"study_design_scores_gemma":[0.0048883255,0.001404549,0.21751074,0.0058652917,0.000030617495,0.000053373744,0.0006920642,0.026939167,0.11332925,0.6226197,0.0048145927,0.0018523141],"about_ca_topic_score_codex":0.00015206075,"about_ca_topic_score_gemma":0.0008786609,"teacher_disagreement_score":0.8211295,"about_ca_system_score_codex":0.00026121186,"about_ca_system_score_gemma":0.00054629776,"threshold_uncertainty_score":0.9999252},"labels":[],"label_agreement":null},{"id":"W4401446843","doi":"10.1016/j.psyneuen.2024.107162","title":"Associations between prenatal stress with offspring inflammation, depression and anxiety","year":2024,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Ottawa","funders":"National Institute of Child Health and Human Development; National Institutes of Health; National Institute of Mental Health; Medical Research Council; University of Bristol; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canada Research Chairs; Wellcome Trust","keywords":"Prenatal stress; Offspring; Anxiety; Depression (economics); Clinical psychology; Psychology; Inflammation; Mental health; Generalized anxiety disorder; Medicine; Psychiatry; Pregnancy; Internal medicine; Biology","score_opus":0.019004950881240303,"score_gpt":0.27313908897573924,"score_spread":0.2541341380944989,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401446843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939184,0.00025048657,0.0005486302,0.0018290755,0.0003414326,0.00021080898,0.00009210785,0.00038316645,0.002425866],"genre_scores_gemma":[0.99908155,0.0002826895,0.00011575739,0.00013640536,0.00013392507,0.00002227219,0.000012838784,0.000025432519,0.00018910815],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99866205,0.00010596725,0.00018566399,0.0005536446,0.00016374499,0.00032895367],"domain_scores_gemma":[0.9994037,0.00025565687,0.000051341736,0.00020126009,0.000016609758,0.00007140654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000024025041,0.00014780324,0.00014541273,0.00015007665,0.00015647328,0.00010368355,0.0001614405,0.00003614659,0.000026776615],"category_scores_gemma":[0.000118851705,0.00012343889,0.000029979514,0.00028063555,0.00013004418,0.00025220675,0.00007922945,0.00026490667,0.0000473631],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013126411,0.0001581331,0.574003,0.00034509142,0.00011414746,0.00048134878,0.0015755388,0.00013408388,0.18922192,0.023329077,0.0020913917,0.20841503],"study_design_scores_gemma":[0.0011110229,0.00015408914,0.48937795,0.00013386802,0.000035651632,0.0003268498,0.000058158123,0.0004265872,0.48791012,0.0018838006,0.018169887,0.0004120028],"about_ca_topic_score_codex":0.00001166181,"about_ca_topic_score_gemma":0.000020642117,"teacher_disagreement_score":0.2986882,"about_ca_system_score_codex":0.000014097835,"about_ca_system_score_gemma":0.000020802836,"threshold_uncertainty_score":0.50336915},"labels":[],"label_agreement":null},{"id":"W4401468015","doi":"10.1016/j.neuroscience.2024.08.007","title":"The enduring effects of antimicrobials and lipopolysaccharide on the cellular mechanisms and behaviours associated with neurodegeneration in pubertal male and female CD1 mice","year":2024,"lang":"en","type":"article","venue":"Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ottawa","keywords":"Neurodegeneration; Neuroscience; Lipopolysaccharide; Biology; Psychology; Medicine; Immunology; Disease; Internal medicine","score_opus":0.014477936332876983,"score_gpt":0.21969433589658585,"score_spread":0.20521639956370888,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401468015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984745,0.00018485844,0.000084677784,0.00058062153,0.00024253564,0.00035318392,0.0000069306057,0.000028465809,0.000044227985],"genre_scores_gemma":[0.9990269,0.00021542831,0.000011495701,0.0005746168,0.0000074241243,0.000013601026,2.2710485e-7,0.000013883791,0.00013645214],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986993,0.00019019598,0.00013933096,0.0004947512,0.00022916262,0.0002472577],"domain_scores_gemma":[0.99883443,0.00090287585,0.000059423674,0.00014718817,0.000009209654,0.000046889236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028827856,0.00013762053,0.0001101566,0.00007857422,0.00033029148,0.00030293965,0.0001828527,0.000035930665,0.0000011186188],"category_scores_gemma":[0.00068713987,0.000081864135,0.000016257995,0.00032586264,0.00045212664,0.0002035752,0.00009313936,0.00018080937,4.4338609e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009371624,0.000026850714,0.0004180078,0.000020212221,4.5512184e-7,0.000050031394,0.00021353197,0.00001739828,0.993346,0.0053761234,0.000007934706,0.0005141132],"study_design_scores_gemma":[0.00017378485,0.0001803573,0.015295675,0.00008624616,0.0000068769014,0.000039808485,0.000031401047,0.003932654,0.98003054,0.00011768902,0.000009755516,0.00009519503],"about_ca_topic_score_codex":0.00003320369,"about_ca_topic_score_gemma":0.000082291335,"teacher_disagreement_score":0.014877668,"about_ca_system_score_codex":0.000008480781,"about_ca_system_score_gemma":0.000025102783,"threshold_uncertainty_score":0.33383223},"labels":[],"label_agreement":null},{"id":"W4401484666","doi":"10.1007/s00213-024-06666-x","title":"Retraction Note: MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials","year":2024,"lang":"en","type":"retraction","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"MDMA; Randomized controlled trial; Psychotherapist; Psychology; Psychiatry; Clinical psychology; Medicine; Internal medicine","score_opus":0.16454947707858503,"score_gpt":0.4930338588089468,"score_spread":0.32848438173036176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401484666","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14126958,0.01801352,0.46659237,0.005789256,0.04924462,0.2996217,0.018327363,0.00048000898,0.00066157675],"genre_scores_gemma":[0.851811,0.03930989,0.005887027,0.0024023664,0.0041373703,0.086459205,0.0026689058,0.0005256632,0.006798572],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.98284304,0.01054632,0.0043175323,0.001319533,0.00059794384,0.00037561206],"domain_scores_gemma":[0.91216826,0.08248321,0.004543519,0.00037677126,0.00030249785,0.00012571974],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.013779582,0.0007739842,0.011943224,0.0028981355,0.00016126552,0.000074943666,0.00022429404,0.00078684045,0.00084983074],"category_scores_gemma":[0.008104454,0.0005367563,0.004597229,0.0011454149,0.00021701405,0.00009287497,0.000003774335,0.00024611244,0.0000028237193],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.6526081,0.013756364,1.2995307e-7,0.00017559229,0.01201484,0.0000036662034,0.00026878322,0.00053508586,0.27284178,0.000027195038,0.0080539,0.039714545],"study_design_scores_gemma":[0.81537426,0.011330532,0.0000014504745,0.00005056218,0.05321104,0.0000013087802,0.000052782834,0.07266564,0.03893208,0.000401047,0.007625751,0.00035357932],"about_ca_topic_score_codex":0.0000144401865,"about_ca_topic_score_gemma":0.000013365229,"teacher_disagreement_score":0.7105414,"about_ca_system_score_codex":0.00017526773,"about_ca_system_score_gemma":0.00043768095,"threshold_uncertainty_score":0.9997084},"labels":[{"model":"gemma","categories":["research_integrity"],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":["research_integrity"],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"agree"},{"id":"W4401553417","doi":"10.1111/appy.12564","title":"Bipolar disorder and oxidative stress: A bibliometric perspective","year":2024,"lang":"en","type":"article","venue":"Asia-Pacific Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Universidade de Macau","keywords":"Perspective (graphical); Oxidative stress; Psychology; Chemistry; Computer science; Biochemistry; Artificial intelligence","score_opus":0.014874797055303032,"score_gpt":0.27652415313103884,"score_spread":0.2616493560757358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401553417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77969354,0.11297062,0.0010651347,0.012380666,0.0049682977,0.00089142355,0.00041324247,0.0011719198,0.086445145],"genre_scores_gemma":[0.9956457,0.0020858266,0.0004119316,0.00024265803,0.00021263245,0.00003185433,0.0000047055946,0.000054850338,0.001309841],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99789524,0.00012003251,0.00022395552,0.0009418008,0.00037056833,0.000448387],"domain_scores_gemma":[0.9991263,0.00026971794,0.0000540906,0.0003464987,0.000036626698,0.00016678023],"candidate_categories":["metaepi_narrow","bibliometrics"],"consensus_categories":[],"category_scores_codex":[0.00012842352,0.00029158616,0.00020964061,0.009407952,0.00022910417,0.0003614685,0.00028403007,0.00012140962,0.00023529906],"category_scores_gemma":[0.00026316696,0.00025260446,0.000120738485,0.029241286,0.00030237137,0.00047908697,0.00009340473,0.0003900139,0.00031597048],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024162851,0.002071098,0.081559785,0.0007456881,0.0003003865,0.0001613668,0.010701278,0.00001207645,0.070281036,0.6249033,0.0672802,0.14174213],"study_design_scores_gemma":[0.004223962,0.0017297714,0.13517202,0.00089028064,0.00019363085,0.0004985456,0.13953196,0.0020312734,0.03553429,0.14147864,0.53498256,0.0037330524],"about_ca_topic_score_codex":0.00006545296,"about_ca_topic_score_gemma":0.000044224238,"teacher_disagreement_score":0.4834247,"about_ca_system_score_codex":0.000046641595,"about_ca_system_score_gemma":0.00014138936,"threshold_uncertainty_score":0.9999926},"labels":[{"model":"gemma","categories":["bibliometrics"],"domain":null,"study_design":"observational","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":["bibliometrics"],"domain":null,"study_design":"design_other","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"split"},{"id":"W4401921867","doi":"10.1192/j.eurpsy.2024.149","title":"Significant beneficial effects of 12-weeks add-on yoga therapy on antipsychotic-stabilized schizophrenia patients through epigenetic modulation: novel findings from a randomized controlled study","year":2024,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Schizophrenia (object-oriented programming); Antipsychotic; Epigenetics; Medicine; Randomized controlled trial; Psychiatry; Psychology; Oncology; Psychotherapist; Internal medicine; Biology; Genetics","score_opus":0.01791289853526804,"score_gpt":0.2569247567140216,"score_spread":0.23901185817875356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401921867","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851099,0.0005643075,0.00039412125,0.0001795491,0.00544421,0.00483762,0.000090497946,0.000254917,0.003124878],"genre_scores_gemma":[0.9980325,0.00008220796,0.0003337321,0.0008146199,0.00036301016,0.00013510123,0.000016241378,0.00013289104,0.00008970294],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.994881,0.0016703961,0.0010409434,0.0011972402,0.00080308097,0.00040735744],"domain_scores_gemma":[0.99648166,0.002370402,0.00030235792,0.00069339573,0.00004622803,0.000105953375],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00058624434,0.0005548143,0.0012530092,0.00026619478,0.00021234261,0.00017045192,0.00054878363,0.00008241821,0.00018554502],"category_scores_gemma":[0.0007680418,0.0004061847,0.0006368275,0.00048288004,0.00019344217,0.00013286591,0.000054691613,0.000396255,0.00019517496],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.8357149,0.018603275,0.0026636566,0.00021978388,0.00087761105,0.000058561818,0.013957282,0.0008153244,0.107905544,0.009834348,0.0017103102,0.0076394193],"study_design_scores_gemma":[0.9214444,0.0041759633,0.057365377,0.0009021499,0.00020330814,7.6865473e-7,0.00026832492,0.0013637642,0.010119921,0.0030254542,0.00024010257,0.00089044153],"about_ca_topic_score_codex":0.000016650009,"about_ca_topic_score_gemma":0.0000066129132,"teacher_disagreement_score":0.09778563,"about_ca_system_score_codex":0.000025947716,"about_ca_system_score_gemma":0.00007382654,"threshold_uncertainty_score":0.999839},"labels":[],"label_agreement":null},{"id":"W4401923757","doi":"10.1016/j.neuropharm.2024.110132","title":"Rapid reorganization of serotonin projections and antidepressant response to 5-HT1A-biased agonist NLX-101 in fluoxetine-resistant cF1ko mice","year":2024,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Fluoxetine; Agonist; Antidepressant; Serotonin; Pharmacology; Psychology; Serotonin Agonist; 5-HT receptor; Partial agonist; Psychotherapist; Neuroscience; Medicine; Receptor; Internal medicine; Hippocampus","score_opus":0.022740440826711998,"score_gpt":0.29693182519215966,"score_spread":0.27419138436544765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401923757","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99409616,0.00020299868,0.000037891852,0.003381528,0.00068804057,0.0009290036,0.00006043798,0.00017069315,0.00043321922],"genre_scores_gemma":[0.997196,0.00021604817,0.00008989953,0.0019026905,0.000049732647,0.0000729947,0.000002623611,0.000048253984,0.000421714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975143,0.00086541736,0.0003964015,0.0006988418,0.00018146732,0.00034356897],"domain_scores_gemma":[0.9985761,0.0010005134,0.00007051116,0.00019221826,0.000046142748,0.00011449262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030783517,0.00019769646,0.00024250938,0.00052738894,0.000121204204,0.00006262636,0.00022862817,0.00008192819,0.00019159858],"category_scores_gemma":[0.0012228226,0.00019752956,0.0000449558,0.0014674334,0.00020141932,0.00012818103,0.0001397411,0.00028563704,0.000045632536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017525264,0.00015156696,0.0002663371,0.00010277338,0.000005182827,0.0003580998,0.0005442857,0.000092391885,0.9937512,0.00021421703,0.0018270946,0.00093430595],"study_design_scores_gemma":[0.0013190437,0.0005423093,0.024718273,0.000044192915,0.000020864749,0.00007772163,0.00008315567,0.0013573363,0.9478822,0.00004152626,0.023694187,0.00021921015],"about_ca_topic_score_codex":0.000052612453,"about_ca_topic_score_gemma":0.00003058083,"teacher_disagreement_score":0.04586904,"about_ca_system_score_codex":0.00004059867,"about_ca_system_score_gemma":0.00016016084,"threshold_uncertainty_score":0.8055022},"labels":[],"label_agreement":null},{"id":"W4402004259","doi":"10.1016/j.scog.2024.100328","title":"Neuroinflammation and kynurenines in schizophrenia: Impact on cognition depending on cognitive functioning and modulatory properties in relation to cognitive remediation and aerobic exercise","year":2024,"lang":"en","type":"article","venue":"Schizophrenia Research Cognition","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Ministero della Salute","keywords":"Cognitive remediation therapy; Cognition; Psychology; Schizophrenia (object-oriented programming); Cognitive skill; Aerobic exercise; Neuroinflammation; Psychosis; Cognitive psychology; Clinical psychology; Neuroscience; Psychiatry; Medicine; Inflammation; Physical therapy","score_opus":0.056002809717963474,"score_gpt":0.32734324215852334,"score_spread":0.2713404324405599,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402004259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961284,0.0006087335,0.00007628213,0.00035701907,0.00015518493,0.002040241,0.000045224937,0.00014693421,0.0004420186],"genre_scores_gemma":[0.9983618,0.0008267648,0.000039718594,0.000079418336,0.0001304358,0.00038451157,0.00008845934,0.00005753935,0.000031311203],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99636537,0.00071827124,0.00043675012,0.0011198731,0.00081295066,0.0005467609],"domain_scores_gemma":[0.9978575,0.0015401705,0.00007760783,0.00011370985,0.00019704303,0.00021398264],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011590958,0.00035417345,0.00028902,0.0025585128,0.0004186585,0.00053117855,0.00007051564,0.00020094839,0.000023195054],"category_scores_gemma":[0.0033570637,0.00032658217,0.000043790795,0.0015048609,0.0002919051,0.0012188168,0.00010244702,0.0010032931,0.000078672914],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03052771,0.0004696556,0.0020476151,0.0008082588,0.00004146798,0.00026153942,0.0051842383,0.00043655685,0.47805253,0.0024233854,0.000063307765,0.47968376],"study_design_scores_gemma":[0.013683536,0.0031046022,0.66170865,0.01924072,0.000098142904,0.00011998533,0.002859768,0.041175853,0.23776896,0.018962886,0.0000075073244,0.001269366],"about_ca_topic_score_codex":0.000041593143,"about_ca_topic_score_gemma":0.0001853798,"teacher_disagreement_score":0.65966105,"about_ca_system_score_codex":0.00015340114,"about_ca_system_score_gemma":0.00012677533,"threshold_uncertainty_score":0.99991864},"labels":[],"label_agreement":null},{"id":"W4402134444","doi":"10.1186/s12964-024-01796-3","title":"RIPK1 inhibition mitigates neuroinflammation and rescues depressive-like behaviors in a mouse model of LPS-induced depression","year":2024,"lang":"en","type":"article","venue":"Cell Communication and Signaling","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Shenzhen-Hong Kong Institute of Brain Science; National Natural Science Foundation of China","keywords":"Neuroinflammation; Depression (economics); Sickness behavior; RIPK1; Inflammation; Neuroscience; Medicine; Psychology; Chemistry; Internal medicine; Necroptosis; Biochemistry; Programmed cell death","score_opus":0.0337879714724181,"score_gpt":0.2659596292860787,"score_spread":0.2321716578136606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402134444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99769056,0.0012046676,0.0002587946,0.0001041298,0.000017368397,0.0001889623,0.0000059747463,0.000066356246,0.00046316738],"genre_scores_gemma":[0.9986337,0.000844638,0.00032618127,0.000064112806,0.0000039877064,0.000018629882,0.000010132651,0.000015083873,0.00008357009],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908084,0.00018645241,0.00026011295,0.00024281105,0.00012131788,0.00010845975],"domain_scores_gemma":[0.9993799,0.0002370994,0.000076008124,0.00024273145,0.000021382228,0.000042882803],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017314915,0.00010225919,0.000111118,0.00017082001,0.00012490498,0.000090571986,0.00011314029,0.0000693084,0.000006936294],"category_scores_gemma":[0.00006843333,0.00009936528,0.000026090269,0.00015132513,0.000090620415,0.00031589094,0.000113449634,0.00018701499,0.0000016004944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015760676,0.000035982008,0.00024391536,0.00007937759,6.2952677e-7,0.0000012624382,0.0015382192,0.000788687,0.9953522,0.00037318736,0.000008970839,0.0015617965],"study_design_scores_gemma":[0.00031718018,0.000015861524,0.00024792747,0.00017502767,0.0000055015785,0.0000019232243,0.000239398,0.102253355,0.89538425,0.0012568058,0.000009422534,0.00009336732],"about_ca_topic_score_codex":0.00003583173,"about_ca_topic_score_gemma":0.00002063184,"teacher_disagreement_score":0.101464674,"about_ca_system_score_codex":0.0000115127705,"about_ca_system_score_gemma":0.00002007368,"threshold_uncertainty_score":0.40519983},"labels":[],"label_agreement":null},{"id":"W4402140867","doi":"10.3389/fncel.2024.1471683","title":"Editorial: The roles of peripheral immune cells and their circulatory effector molecules in neuropsychiatric disorders","year":2024,"lang":"en","type":"editorial","venue":"Frontiers in Cellular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Effector; Immune system; Peripheral; Circulatory system; Neuroscience; Medicine; Immunology; Biology; Internal medicine","score_opus":0.004484540515874607,"score_gpt":0.20744871427837258,"score_spread":0.20296417376249798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402140867","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.028219527,0.006488302,0.00037998316,0.00012617394,0.96351165,0.0008608563,0.00018022393,0.00008069672,0.00015258136],"genre_scores_gemma":[0.33858865,0.008351131,0.00012484644,0.00026600235,0.6516824,0.00016152377,0.000021416594,0.00033508684,0.00046895418],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99451554,0.0008425002,0.000819333,0.0017756015,0.0012031625,0.000843861],"domain_scores_gemma":[0.99776256,0.00084336696,0.00035159598,0.0008813496,0.000035513258,0.00012563884],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00080553506,0.00072805403,0.00082737743,0.00077425514,0.00019064645,0.00026496785,0.0019673093,0.00056403974,0.000004564539],"category_scores_gemma":[0.0015381537,0.00054743583,0.0002887362,0.0020446358,0.0015669294,0.0002473814,0.00050698564,0.0020208943,0.000004877868],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006891342,0.00016193754,0.00015389199,0.00032709818,0.0000033002193,0.000026705946,0.00078016985,0.00043370452,0.36691803,0.00002743946,0.62983215,0.0012666581],"study_design_scores_gemma":[0.0011913547,0.00032060946,0.00042102617,0.0002118415,0.000025642303,0.000002698555,0.00041123902,0.0065699485,0.033037506,0.0014818247,0.9553664,0.0009599539],"about_ca_topic_score_codex":0.00007138259,"about_ca_topic_score_gemma":0.00006315307,"teacher_disagreement_score":0.3338805,"about_ca_system_score_codex":0.000106710606,"about_ca_system_score_gemma":0.0003825592,"threshold_uncertainty_score":0.99969774},"labels":[],"label_agreement":null},{"id":"W4402179520","doi":"10.1186/s12888-024-06054-x","title":"Exploring the relationship between lipid metabolism and cognition in individuals living with stable-phase Schizophrenia: a small cross-sectional study using Olink proteomics analysis","year":2024,"lang":"en","type":"article","venue":"BMC Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Cognition; Schizophrenia (object-oriented programming); Confounding; Cross-sectional study; Internal medicine; Montreal Cognitive Assessment; Blood lipids; Psychology; Medicine; Clinical psychology; Psychiatry; Cholesterol; Cognitive impairment; Pathology","score_opus":0.1757618165779702,"score_gpt":0.3429352618218145,"score_spread":0.1671734452438443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402179520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943652,0.00022000355,0.0038446747,0.000061954415,0.00044720987,0.00084180385,0.000061965075,0.00011496776,0.00004218279],"genre_scores_gemma":[0.9956688,0.00000707175,0.003637122,0.000046829507,0.00042207653,0.00016178431,0.0000072042526,0.000032468026,0.000016606708],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99795175,0.00035838937,0.00041948483,0.0006378124,0.0003401848,0.00029236393],"domain_scores_gemma":[0.99866384,0.0008843511,0.00011111752,0.00024396469,0.000024062103,0.00007266853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008023056,0.00021322398,0.00023705527,0.0006743384,0.0004730038,0.000629181,0.00019111794,0.0000651237,0.000011591194],"category_scores_gemma":[0.0004040369,0.00016104012,0.000093217815,0.0022088804,0.00012413987,0.00063338515,0.00008733921,0.0004964206,0.0000055339387],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042589676,0.00019850963,0.99688524,0.00005584367,0.00008610019,6.1128407e-7,0.00096164865,0.0005504202,0.00019325328,0.0009219899,9.780848e-7,0.0001028105],"study_design_scores_gemma":[0.0013215009,0.00006490879,0.9948582,0.00009347836,0.00028889533,0.000008246241,0.00071624207,0.0012468533,0.000085468455,0.0011030344,0.000004526332,0.00020862043],"about_ca_topic_score_codex":0.00006594026,"about_ca_topic_score_gemma":0.000625806,"teacher_disagreement_score":0.0020270194,"about_ca_system_score_codex":0.00003174091,"about_ca_system_score_gemma":0.00020315524,"threshold_uncertainty_score":0.6567026},"labels":[],"label_agreement":null},{"id":"W4402222862","doi":"10.1007/978-3-030-51366-5_83","title":"Neurobiology of Mood Disorders","year":2024,"lang":"en","type":"book-chapter","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Mood disorders; Neuroscience; Psychology; Mood; Psychiatry; Anxiety","score_opus":0.020150223598124194,"score_gpt":0.2391325259503654,"score_spread":0.21898230235224123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402222862","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023247297,0.00009287495,0.000015343603,0.0005888602,0.00064200535,0.00018834107,0.000059107697,0.00015699159,0.998024],"genre_scores_gemma":[0.13556932,0.00045232393,0.00001630529,0.0003766981,0.000044112803,0.0000034103764,0.0000055928867,0.00006091406,0.8634713],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9988809,0.000010780341,0.00025381864,0.0005302157,0.00013521448,0.00018904608],"domain_scores_gemma":[0.9993856,0.00015956534,0.00008531727,0.00031482082,0.00000968253,0.00004499068],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00002734273,0.00025315446,0.00028214185,0.00017328015,0.000024284856,0.000013530286,0.00031875935,0.00023181317,0.0024582117],"category_scores_gemma":[0.00003970026,0.00020800988,0.00021281451,0.00004245665,0.00031854075,0.000028951441,0.00014936793,0.0002981977,0.0010502123],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009377188,0.000016093105,0.000001685756,0.00007379429,0.000009849216,0.0000017345518,0.000024762736,0.0000023531063,0.008298121,0.98731416,0.00287655,0.0013714936],"study_design_scores_gemma":[0.00028651214,0.00025365961,0.000030287172,0.00007558315,0.000028459139,0.000009559355,0.000011939061,0.00002363715,0.022116218,0.532905,0.4437705,0.000488651],"about_ca_topic_score_codex":0.0000054067673,"about_ca_topic_score_gemma":0.000094795854,"teacher_disagreement_score":0.4544092,"about_ca_system_score_codex":0.000008380508,"about_ca_system_score_gemma":0.000032794967,"threshold_uncertainty_score":0.9997276},"labels":[],"label_agreement":null},{"id":"W4402255208","doi":"10.1038/s41380-024-02707-1","title":"Transcriptomic pathology of neocortical microcircuit cell types across psychiatric disorders","year":2024,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital; Centre for Addiction and Mental Health","funders":"","keywords":"Neuroscience; Transcriptome; Psychopharmacology; Cell type; Behavioral medicine; Psychology; Cell; Medicine; Psychiatry; Biology; Genetics; Gene; Gene expression","score_opus":0.007130263725629848,"score_gpt":0.255516115814543,"score_spread":0.24838585208891312,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402255208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9728718,0.008632546,0.0065181796,0.0021759549,0.0029168986,0.00031659083,0.00006151163,0.0002289128,0.0062776324],"genre_scores_gemma":[0.99722123,0.00022392887,0.0007406997,0.0014469544,0.00007564972,0.00002033774,0.000004812984,0.00006776947,0.00019861404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979407,0.00013473199,0.00039695905,0.0007259249,0.0002578694,0.0005438016],"domain_scores_gemma":[0.99934137,0.00006209076,0.000059674738,0.0004147485,0.000013066162,0.00010907229],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011299102,0.00026465475,0.00025795336,0.00016609239,0.00009846112,0.000065429,0.00044417178,0.00015829821,0.00013632467],"category_scores_gemma":[0.000032589778,0.00025476047,0.00035561863,0.0007809599,0.0002791064,0.00009232203,0.000046097535,0.00034986,0.00021532233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048413793,0.00040628642,0.0010119593,0.00039441255,0.00001810133,0.00006248745,0.0005788773,0.00004101955,0.9691383,0.02119887,0.001764667,0.0053365673],"study_design_scores_gemma":[0.0044491566,0.0011068775,0.010603201,0.0001827792,0.00022746203,0.00037340703,0.0011259514,0.001135143,0.8175544,0.12319298,0.037965607,0.0020829998],"about_ca_topic_score_codex":0.000010156347,"about_ca_topic_score_gemma":0.00003376959,"teacher_disagreement_score":0.1515839,"about_ca_system_score_codex":0.00001626014,"about_ca_system_score_gemma":0.00014645908,"threshold_uncertainty_score":0.99999046},"labels":[],"label_agreement":null},{"id":"W4402423383","doi":"10.24908/iqurcp17995","title":"Impact of Social Connectedness on Neuroinflammation and Brain Architecture in Non-Human Primates","year":2024,"lang":"en","type":"article","venue":"Inquiry Queen s Undergraduate Research Conference Proceedings","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Social connectedness; Neuroinflammation; Human brain; Neuroscience; Architecture; Psychology; Cognitive science; Biology; Geography; Social psychology","score_opus":0.07206890265724454,"score_gpt":0.40388355001927945,"score_spread":0.3318146473620349,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402423383","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98252875,0.000015613457,0.000076695,0.013638281,0.000057468817,0.000628672,0.000013043942,0.00012394946,0.0029175146],"genre_scores_gemma":[0.9994469,0.000066530796,0.000016161188,0.000050905805,0.00009393694,0.00005651766,0.0000058001974,0.000040705992,0.00022254145],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99719083,0.00016453124,0.00037999311,0.00076988834,0.00081208284,0.00068268616],"domain_scores_gemma":[0.9986563,0.00077270163,0.00008331529,0.00011799514,0.00023257683,0.00013711827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081122364,0.00027046833,0.0003162484,0.0010717894,0.00024454837,0.0005317578,0.0003997509,0.0001479522,0.00003068839],"category_scores_gemma":[0.0011687402,0.00022702443,0.00009380661,0.0013823197,0.0010275968,0.00046409538,0.00019429052,0.0009261222,0.000021896394],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001774825,0.00012523086,0.00117563,0.00066342845,0.0000150720225,0.00003405041,0.01046077,0.000009296601,0.81183505,0.16666923,0.001564492,0.0072702686],"study_design_scores_gemma":[0.0031600674,0.0037210705,0.15948069,0.0018803987,0.000015453503,0.00007875788,0.0035004558,0.009249737,0.30604863,0.5109176,0.0006527124,0.0012943931],"about_ca_topic_score_codex":0.00015791769,"about_ca_topic_score_gemma":0.000021527292,"teacher_disagreement_score":0.5057864,"about_ca_system_score_codex":0.00014408433,"about_ca_system_score_gemma":0.00027784944,"threshold_uncertainty_score":0.92577875},"labels":[],"label_agreement":null},{"id":"W4402506611","doi":"10.1038/s41380-024-02736-w","title":"Transcriptomic profiles in major depressive disorder: the role of immunometabolic and cell-cycle-related pathways in depression with different levels of inflammation","year":2024,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; H. Lundbeck A/S; Department of Health and Social Care; National Institute for Health and Care Research; Wellcome Trust; European Federation of Pharmaceutical Industries and Associations; Wellcome; Eli Lilly and Company; National Alliance for Research on Schizophrenia and Depression; NIHR Maudsley Biomedical Research Centre; GlaxoSmithKline; NIHR Cambridge Biomedical Research Centre; European Commission; Pfizer; King's College London","keywords":"Transcriptome; Major depressive disorder; Inflammation; Depression (economics); Internal medicine; C-reactive protein; Biological pathway; Bipolar disorder; Medicine; Bioinformatics; Oncology; Endocrinology; Biology; Gene expression; Gene; Genetics; Lithium (medication)","score_opus":0.004791150039200631,"score_gpt":0.20205787242352607,"score_spread":0.19726672238432544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402506611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9836483,0.014995834,0.00017539202,0.00016772104,0.00010168244,0.00051774463,0.000027216054,0.000024688214,0.00034141922],"genre_scores_gemma":[0.99970955,0.00012852607,0.000049259826,0.00002293766,0.0000051954207,0.00005086863,0.000003066637,0.00002500563,0.0000055868513],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998785,0.0001648056,0.0003489601,0.00032144456,0.00019896864,0.00018077726],"domain_scores_gemma":[0.99958473,0.000054730022,0.00009855251,0.00022777845,0.000009140892,0.000025045658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007820107,0.00016567924,0.00020435364,0.00022713542,0.000035932157,0.000025443616,0.0001954716,0.000069279056,0.00001307974],"category_scores_gemma":[0.000017690494,0.00010797199,0.000060634506,0.00045576473,0.00012627599,0.0001059351,0.00003788377,0.00021422439,9.1452534e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008502713,0.00013547005,0.021231612,0.00017581035,0.000009742788,0.000005622691,0.0015196993,0.0003140199,0.9641465,0.003658362,7.6931923e-7,0.008717371],"study_design_scores_gemma":[0.0015504168,0.00006308129,0.19561297,0.0003068528,0.000018335486,0.0000065664053,0.0005835703,0.0025553906,0.7898941,0.00924939,0.00001349996,0.00014579835],"about_ca_topic_score_codex":0.000049349674,"about_ca_topic_score_gemma":0.00011739343,"teacher_disagreement_score":0.17438136,"about_ca_system_score_codex":0.000008848123,"about_ca_system_score_gemma":0.00005461237,"threshold_uncertainty_score":0.44029698},"labels":[],"label_agreement":null},{"id":"W4402515760","doi":"10.17116/jnevro202412408181","title":"Immunological and neuroanatomic markers of the clinical dynamics of MCI and pre-MCI","year":2024,"lang":"en","type":"article","venue":"S S Korsakov Journal of Neurology and Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Dynamics (music); Psychology; Neuroscience; Medicine","score_opus":0.014477815013590488,"score_gpt":0.29012880140550984,"score_spread":0.2756509863919194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402515760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98228085,0.0048440984,0.00002307449,0.010516415,0.0019898992,0.00009717534,0.00001352171,0.0000089720625,0.0002259859],"genre_scores_gemma":[0.99488705,0.0034891479,0.00007135995,0.0014443608,0.00006549521,4.845644e-7,1.3593805e-7,0.000011175385,0.00003079133],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998344,0.0004952863,0.00059690344,0.00026266344,0.00013633847,0.00016479562],"domain_scores_gemma":[0.9987013,0.00074557395,0.0002989831,0.00015911381,0.000023252262,0.00007182449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042836042,0.0001350848,0.00031961445,0.00011695921,0.00007584512,0.000019544317,0.00025133573,0.00018002896,0.000015753641],"category_scores_gemma":[0.000300661,0.00008624745,0.00014056651,0.00018085887,0.001168307,0.000093865914,0.00013114148,0.0008013872,3.4985092e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011331397,0.001046552,0.7844885,0.00092434004,0.0003807363,0.00026386528,0.00090475945,0.000045201632,0.026167354,0.078542665,0.004417043,0.091487594],"study_design_scores_gemma":[0.0017106168,0.003655284,0.95387983,0.00010896453,0.00011561942,0.00314151,0.00013420555,0.00171103,0.0004226673,0.033122744,0.0018195059,0.00017803028],"about_ca_topic_score_codex":0.0000031372003,"about_ca_topic_score_gemma":0.000012022029,"teacher_disagreement_score":0.16939133,"about_ca_system_score_codex":0.0000020948444,"about_ca_system_score_gemma":0.00009030961,"threshold_uncertainty_score":0.43046758},"labels":[],"label_agreement":null},{"id":"W4402533096","doi":"10.1016/j.jpsychires.2024.09.003","title":"Effective action of silymarin against ketamine-induced schizophrenia in male mice: Insight into the biochemical and molecular mechanisms of action","year":2024,"lang":"en","type":"article","venue":"Journal of Psychiatric Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Schizophrenia (object-oriented programming); Ketamine; Action (physics); Pharmacology; Mechanism of action; Neuroscience; Medicine; Psychology; Psychiatry; Chemistry; In vitro; Biochemistry","score_opus":0.04079683366806345,"score_gpt":0.3649038842537623,"score_spread":0.32410705058569883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402533096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99603355,0.0013634983,0.00038239974,0.0010749798,0.0003850872,0.00029536686,0.000001252319,0.000005225349,0.00045865134],"genre_scores_gemma":[0.99879664,0.00072170317,0.00032008893,0.000031140393,0.00008492381,0.0000069236435,2.619869e-7,0.000013908311,0.000024380515],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978204,0.0005767224,0.00041935506,0.00022846578,0.00075496425,0.000200087],"domain_scores_gemma":[0.9988379,0.00065219594,0.00016259869,0.00015112004,0.00012738685,0.00006882859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012397433,0.00010436848,0.00020416152,0.0009838353,0.00006685988,0.000048666087,0.00028670538,0.000111245135,0.000011867943],"category_scores_gemma":[0.00064017763,0.00007129001,0.00011242999,0.0017990026,0.0001426311,0.00016382404,0.000070028545,0.00083823816,0.0000029971875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004359815,0.00013829325,0.00006789723,0.0001911193,0.00001581456,0.00002744591,0.00048309393,0.0000099683375,0.97323793,0.0012919236,0.00015493584,0.0239456],"study_design_scores_gemma":[0.0008276811,0.00051676034,0.0027243565,0.00010214934,0.000010452284,0.000058224658,0.00052322994,0.00047244024,0.98745525,0.007169196,0.000074358984,0.00006588679],"about_ca_topic_score_codex":0.000054147822,"about_ca_topic_score_gemma":0.000018506895,"teacher_disagreement_score":0.023879714,"about_ca_system_score_codex":0.00007865716,"about_ca_system_score_gemma":0.00018119022,"threshold_uncertainty_score":0.36417744},"labels":[],"label_agreement":null},{"id":"W4402884739","doi":"10.1101/2024.09.25.614771","title":"Integrative systems neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Fundação para a Ciência e a Tecnologia; Fundação Champalimaud","keywords":"Neuroimmunology; PAX6; Transcriptome; Major depressive disorder; Peripheral blood mononuclear cell; Immune system; Neuroscience; Central nervous system; Biology; Amygdala; Gene; Psychology; Immunology; Gene expression; Genetics","score_opus":0.017647009223331223,"score_gpt":0.2590853737594137,"score_spread":0.24143836453608247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402884739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9805852,0.01010771,0.0010063506,0.00051349215,0.0044931336,0.001531681,0.0007969955,0.00081398705,0.0001514087],"genre_scores_gemma":[0.9978038,0.0003703612,0.0003603222,0.0002894329,0.000338287,0.00053945644,3.9250594e-7,0.00025158975,0.000046336834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99395555,0.00090996217,0.0011860054,0.00220222,0.0007553355,0.0009909433],"domain_scores_gemma":[0.9957626,0.0010711794,0.0006413815,0.0017296196,0.00047978817,0.000315431],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038271406,0.0010103552,0.0012907007,0.0005934493,0.00027136464,0.0005160776,0.0014070717,0.0009234866,0.000082599996],"category_scores_gemma":[0.005943608,0.0009296456,0.00038266697,0.0008377115,0.0011611454,0.0002537758,0.0018720662,0.002168667,0.00017862758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012055916,0.0002754185,0.0006571396,0.0017204289,0.00011413011,0.00030256907,0.00008691722,0.00006890512,0.9783723,0.017701114,0.00057777937,0.0000027388292],"study_design_scores_gemma":[0.0012447913,0.00026274947,0.009019592,0.004355692,0.0002804161,6.718167e-7,0.000074837975,0.0015431028,0.97959214,0.0003372804,0.001793129,0.001495592],"about_ca_topic_score_codex":0.00014467309,"about_ca_topic_score_gemma":0.0000016883024,"teacher_disagreement_score":0.017363833,"about_ca_system_score_codex":0.00021929212,"about_ca_system_score_gemma":0.00093035056,"threshold_uncertainty_score":0.99931544},"labels":[],"label_agreement":null},{"id":"W4402975549","doi":"10.1016/j.molmed.2024.09.002","title":"Microbes and mood: innovative biomarker approaches in depression","year":2024,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Hersh Foundation; Rose Foundation for Communities and the Environment","keywords":"Biomarker; Depression (economics); Mood; Psychology; Medicine; Computational biology; Biology; Psychiatry; Genetics; Economics","score_opus":0.11603606274469369,"score_gpt":0.3695404939017648,"score_spread":0.2535044311570711,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402975549","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023227406,0.9894453,0.000030651845,0.0002333084,0.00017725767,0.0002871656,0.000012647791,0.00004482446,0.009536546],"genre_scores_gemma":[0.0033756609,0.995508,0.0000965374,0.00021924352,0.000035970163,0.00009433005,0.000058197867,0.00006900611,0.00054304616],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975971,0.0003055102,0.0005991614,0.0009061445,0.000262073,0.00033001884],"domain_scores_gemma":[0.9993142,0.00015245049,0.0001333904,0.0003283155,0.000008126056,0.00006355048],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029824118,0.00046980593,0.0011294179,0.0018615323,0.000021937794,0.000024600879,0.00030162337,0.00027337615,0.000058957598],"category_scores_gemma":[0.00033114335,0.00031047154,0.00008851859,0.003929841,0.0003678696,0.0000517456,0.00021371209,0.0006444256,0.000013144621],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006469233,0.000054228985,0.0000064766573,0.0030467492,0.000014423236,0.00038011873,0.0002510051,2.0974495e-7,0.0019749673,0.00047857102,0.0007091482,0.99307764],"study_design_scores_gemma":[0.0020539714,0.00014145633,0.000273766,0.04681429,0.00025338162,0.00026274056,0.00018075775,0.00010383424,0.001336086,0.0008887785,0.94666505,0.001025871],"about_ca_topic_score_codex":0.000026074998,"about_ca_topic_score_gemma":0.00002817709,"teacher_disagreement_score":0.9920518,"about_ca_system_score_codex":0.000057128647,"about_ca_system_score_gemma":0.000048100323,"threshold_uncertainty_score":0.99993473},"labels":[],"label_agreement":null},{"id":"W4402990365","doi":"10.3390/nu16193309","title":"Oral Trehalose Intake Modulates the Microbiota–Gut–Brain Axis and Is Neuroprotective in a Synucleinopathy Mouse Model","year":2024,"lang":"en","type":"article","venue":"Nutrients","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Fondation CHU de Québec; Université Laval","keywords":"Neuroprotection; Gut–brain axis; Trehalose; Gut flora; Biology; Neuroscience; Immunology; Biochemistry","score_opus":0.01996092809084269,"score_gpt":0.2487844926830791,"score_spread":0.2288235645922364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402990365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995681,0.00019211335,0.0000851029,0.0027110053,0.00013195106,0.00057753635,0.00010932764,0.0001305001,0.0003814509],"genre_scores_gemma":[0.9956883,0.000076368786,0.0000580916,0.0027817816,0.00001948332,0.000042854008,0.0000015581888,0.000041401796,0.0012901509],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841934,0.00013949587,0.00021024943,0.00066829316,0.00020398064,0.00035866097],"domain_scores_gemma":[0.9994143,0.00016349528,0.000035502773,0.00029577277,0.000015368443,0.00007552381],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013814375,0.00022159693,0.0001715785,0.00018946262,0.00013678032,0.00020109075,0.00029913388,0.00008736135,0.000021983658],"category_scores_gemma":[0.0002130688,0.00016299145,0.000071582515,0.0005944276,0.00022571781,0.00024542672,0.00016686485,0.00035869083,0.000057499317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014530614,0.0003045277,0.0002742275,0.0000716921,0.000009584185,0.000070283815,0.0067817313,0.0001415452,0.97690827,0.0019499144,0.0029514222,0.010391505],"study_design_scores_gemma":[0.0035272252,0.00047043982,0.005625991,0.00022028756,0.000020633317,0.00007193397,0.00084392936,0.23481505,0.7261154,0.013040081,0.014323338,0.00092571636],"about_ca_topic_score_codex":0.000045111436,"about_ca_topic_score_gemma":0.000010107158,"teacher_disagreement_score":0.25079286,"about_ca_system_score_codex":0.000048717873,"about_ca_system_score_gemma":0.00003189038,"threshold_uncertainty_score":0.66465986},"labels":[],"label_agreement":null},{"id":"W4403079859","doi":"10.1017/s003329172400206x","title":"Longitudinal course of inflammatory-cognitive subgroups across first treatment severe mental illness and healthy controls","year":2024,"lang":"en","type":"article","venue":"Psychological Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Helse Sør-Øst RHF; Norges Forskningsråd; Universitetet i Oslo","keywords":"Cognition; Schizophrenia (object-oriented programming); Bipolar disorder; Longitudinal study; Medicine; Internal medicine; Clinical psychology; Psychology; Psychiatry; Pathology","score_opus":0.049927825888020666,"score_gpt":0.37535305324745816,"score_spread":0.32542522735943746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403079859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893186,0.0025695742,0.00006768426,0.005655624,0.0006281512,0.00052561605,0.00011573037,0.00010676089,0.0010122459],"genre_scores_gemma":[0.99734217,0.0010685635,0.0000067006586,0.0012434653,0.00016402233,0.000058911017,0.0000080929,0.000013446938,0.000094616196],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9984185,0.0000945743,0.0003097476,0.00058711856,0.00023713446,0.0003529232],"domain_scores_gemma":[0.99878514,0.000794945,0.0000686667,0.00014535502,0.000022861277,0.00018304502],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019090208,0.00022498016,0.00037194148,0.00004650157,0.00016963114,0.000022487,0.00012122528,0.00009814013,0.00036849367],"category_scores_gemma":[0.00024281755,0.00013224955,0.0000629905,0.00023501016,0.0010028459,0.00008564029,0.000038202434,0.0001627945,0.00002710891],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008504618,0.00476505,0.039359834,0.0008698143,0.00031559786,0.0022146334,0.036124803,0.000004690678,0.098609425,0.010720953,0.007530711,0.79097986],"study_design_scores_gemma":[0.032566763,0.026102856,0.887655,0.0016378466,0.00015826753,0.0016976792,0.011717638,0.0005176181,0.013118603,0.004278107,0.019289201,0.0012604076],"about_ca_topic_score_codex":0.000016455426,"about_ca_topic_score_gemma":0.000030304649,"teacher_disagreement_score":0.84829515,"about_ca_system_score_codex":0.00003465476,"about_ca_system_score_gemma":0.00000833596,"threshold_uncertainty_score":0.53929806},"labels":[],"label_agreement":null},{"id":"W4403108270","doi":"10.1192/bjo.2024.735","title":"Associations between C-reactive protein and individual symptoms of depression in a lower-middle income country","year":2024,"lang":"en","type":"article","venue":"BJPsych Open","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Department of Psychiatry, University of Toronto; University of Toronto","keywords":"Medicine; Odds ratio; Internal medicine; Depression (economics); Population; Major depressive disorder; Environmental health","score_opus":0.04914062081896345,"score_gpt":0.3180014132805284,"score_spread":0.2688607924615649,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403108270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990558,0.00012168752,0.000013788329,0.00019920089,0.00009782209,0.0011568117,0.00032135774,0.000034882472,0.0074964217],"genre_scores_gemma":[0.9993751,0.000003965902,0.000082934006,0.00009155995,0.00002861339,0.00008099158,0.000014211982,0.0000150838905,0.00030754416],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988926,0.00010562577,0.00022424285,0.00035522052,0.00024377038,0.00017853169],"domain_scores_gemma":[0.9994435,0.00026109687,0.00007608198,0.00015779883,0.00001203471,0.000049491075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002823712,0.000103457925,0.00019132899,0.00013123875,0.00006287688,0.00018317711,0.000391435,0.000086090964,0.000035848752],"category_scores_gemma":[0.00023495936,0.00009170732,0.000024122899,0.0004927603,0.00007533669,0.00042059444,0.0002792962,0.00018496314,0.00001812625],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030560236,0.0012231572,0.6711121,0.00039936774,0.00016226851,0.00010254903,0.008948823,0.000012251656,0.20139977,0.021729382,0.0015909104,0.09301378],"study_design_scores_gemma":[0.0012582956,0.00018806466,0.94676954,0.0007342573,0.000014925358,0.0000030358785,0.00014437937,0.00006656283,0.04174364,0.0060413005,0.0027723215,0.00026367806],"about_ca_topic_score_codex":0.000212785,"about_ca_topic_score_gemma":0.00008142276,"teacher_disagreement_score":0.27565742,"about_ca_system_score_codex":0.000035183668,"about_ca_system_score_gemma":0.000082643186,"threshold_uncertainty_score":0.37397158},"labels":[],"label_agreement":null},{"id":"W4403118650","doi":"10.1038/s41467-024-52974-3","title":"Astrocytic neuroligin 3 regulates social memory and synaptic plasticity through adenosine signaling in male mice","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Canada Research Chairs; University of Toronto; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children; Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China; Government of Canada","keywords":"Neuroligin; Synaptic plasticity; Neuroscience; Adenosine; Synapse; Biology; Neuroplasticity; Metaplasticity; Signal transduction; Cell biology; Excitatory postsynaptic potential; Endocrinology; Genetics","score_opus":0.029588281675478032,"score_gpt":0.29784009789263405,"score_spread":0.268251816217156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403118650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97772044,0.008979859,0.00007308586,0.00965053,0.00016560749,0.00023964504,0.00002556355,0.000188886,0.0029563704],"genre_scores_gemma":[0.9978483,0.00030903853,0.000659058,0.0009779097,0.000043673263,0.000019394447,0.000006395184,0.000018803134,0.00011747044],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901956,0.0001816069,0.00017597257,0.00028662678,0.00013510235,0.00020112284],"domain_scores_gemma":[0.99844664,0.0011503558,0.000034973196,0.00031812725,0.000017953,0.00003194089],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000082352424,0.00012503707,0.00012877134,0.00010940176,0.00027098984,0.00010916395,0.0005743997,0.00016125881,0.000026016522],"category_scores_gemma":[0.00041957365,0.00012369662,0.00004111379,0.0005369563,0.00028855816,0.0002170073,0.00025887263,0.0010114277,0.000022540553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061617284,0.00028729154,0.00028482144,0.00017679481,0.000029626597,0.000058771187,0.0050562574,0.00023206281,0.89984995,0.0870635,0.0044661397,0.0024331785],"study_design_scores_gemma":[0.006523542,0.0005631602,0.06450073,0.001738984,0.00038532933,0.0013507145,0.0049900026,0.1930663,0.5694436,0.044413995,0.1093557,0.003667942],"about_ca_topic_score_codex":0.000015127968,"about_ca_topic_score_gemma":0.00010950671,"teacher_disagreement_score":0.33040634,"about_ca_system_score_codex":0.00003995508,"about_ca_system_score_gemma":0.000051355662,"threshold_uncertainty_score":0.50442016},"labels":[],"label_agreement":null},{"id":"W4403159363","doi":"10.7759/cureus.70912","title":"Serotonin Availability Shapes the Effects of Phenelzine on Inflammatory Response and Gene Expression in Macrophages","year":2024,"lang":"en","type":"article","venue":"Cureus","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dr. Georges-L.-Dumont University Hospital Centre; Atlantic Cancer Research Institute","funders":"Golestan University of Medical Sciences","keywords":"Medicine; Phenelzine; Gene expression; Gene; Inflammatory response; Serotonin; Inflammation; Genetics; Immunology; Pharmacology; Internal medicine; Biochemistry; Enzyme; Biology","score_opus":0.012397496660917348,"score_gpt":0.25800978116161255,"score_spread":0.2456122845006952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403159363","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963167,0.0026811755,0.000006829139,0.00026202286,0.00015867646,0.00035818465,0.0000061319492,0.00005220342,0.0001581214],"genre_scores_gemma":[0.9992971,0.0002278297,0.000028651406,0.00018190507,0.000021736048,0.00003893939,2.1548975e-7,0.000011879703,0.00019173302],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989158,0.0003514082,0.00014139495,0.0003022794,0.00014856941,0.00014056476],"domain_scores_gemma":[0.998132,0.001589449,0.000027532933,0.00021150643,0.000006468608,0.00003304534],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030231845,0.00010613889,0.000104727485,0.000052071602,0.000048484788,0.00003180983,0.00016500583,0.000050285602,0.00004305104],"category_scores_gemma":[0.0011970758,0.00006751299,0.000031354757,0.00016561101,0.00017643267,0.000085253676,0.0000871418,0.0001375734,0.000018674069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029108537,0.000048799324,0.00057888514,0.00017511124,0.0000014743077,0.00004848565,0.00080126524,0.000010000786,0.99611366,0.00014363881,0.000264249,0.00152335],"study_design_scores_gemma":[0.00027445954,0.00012859194,0.067121394,0.0001527096,0.000001616006,0.000003509395,0.000035163208,0.00016867695,0.93073094,0.0004327427,0.00088154175,0.00006864236],"about_ca_topic_score_codex":0.0000040790765,"about_ca_topic_score_gemma":0.000006571696,"teacher_disagreement_score":0.066542506,"about_ca_system_score_codex":0.000021557787,"about_ca_system_score_gemma":0.000029643947,"threshold_uncertainty_score":0.27530998},"labels":[],"label_agreement":null},{"id":"W4403190877","doi":"10.1080/2162402x.2024.2413719","title":"Benzodiazepines compromise the outcome of cancer immunotherapy","year":2024,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"HORIZON EUROPE European Research Council; Agence Nationale de la Recherche; HORIZON EUROPE Framework Programme; Cancéropôle Ile de France; Institut National Du Cancer; Institut Universitaire de France; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Labex Immuno-Oncology; Association pour la Recherche sur le Cancer; Seerave Foundation; European Commission","keywords":"Medicine; Cancer immunotherapy; Immunotherapy; Compromise; Cancer; Internal medicine; Political science","score_opus":0.042816880718713604,"score_gpt":0.34140930155500787,"score_spread":0.2985924208362943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403190877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9694555,0.019036474,0.000062905325,0.0063217375,0.0016338595,0.00023657389,0.000025583095,0.0002849512,0.0029424652],"genre_scores_gemma":[0.99586993,0.0014034295,0.000027064701,0.0011375136,0.000048313555,0.000046996483,8.33909e-7,0.000029773943,0.0014361135],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99909055,0.0001046398,0.00024483565,0.000240388,0.0001035788,0.00021601589],"domain_scores_gemma":[0.99924177,0.00036313856,0.00005559111,0.0003130744,0.0000137030665,0.000012744715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009581073,0.00011837153,0.0001894687,0.00007696782,0.000067379515,0.000028386257,0.00043277725,0.000070578375,0.00042414985],"category_scores_gemma":[0.00007755335,0.00007373468,0.00010745366,0.00029259906,0.0004294341,0.00006739989,0.00006281583,0.00020129842,0.00008448564],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058253627,0.000062434636,0.0011867774,0.00003597316,0.000037202717,0.000011687958,0.00080711796,0.000020713425,0.90505844,0.02028224,0.0009911574,0.071448006],"study_design_scores_gemma":[0.0012695303,0.00025524368,0.04592364,0.000084719126,0.0000205078,0.000046845867,0.00036343807,0.0007018383,0.38189787,0.0052896887,0.56378937,0.00035733133],"about_ca_topic_score_codex":0.00023787345,"about_ca_topic_score_gemma":0.000047540532,"teacher_disagreement_score":0.5627982,"about_ca_system_score_codex":0.000024605917,"about_ca_system_score_gemma":0.000047857862,"threshold_uncertainty_score":0.46441433},"labels":[],"label_agreement":null},{"id":"W4403198627","doi":"10.1111/all.16318","title":"The epithelial barrier theory and its associated diseases","year":2024,"lang":"en","type":"review","venue":"Allergy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Science Foundation; LEO Fondet; European Academy of Allergy and Clinical Immunology; Promedica Stiftung; Biotechnology and Biological Sciences Research Council; Asthma and Lung UK; National Institute for Health and Care Research; National Institutes of Health; Rosetrees Trust; Regeneron Pharmaceuticals; LEO Pharma; Immune Tolerance Network; European Commission; Sanofi; Incyte; Pfizer; Novartis Pharmaceuticals Corporation; Allergy Therapeutics; AstraZeneca; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Food Allergy Research and Education; Amgen","keywords":"Dysbiosis; Inflammation; Immunology; Immune system; Commensalism; Colonization; Biology; Medicine; Microbiology; Gut flora; Genetics; Bacteria","score_opus":0.03178870411822256,"score_gpt":0.30640632759073755,"score_spread":0.274617623472515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403198627","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00001804045,0.99634856,4.5647334e-7,0.000077445,0.0007190745,0.0002811067,0.00033293385,0.00012210953,0.0021002903],"genre_scores_gemma":[0.00016502356,0.98731196,2.1181164e-7,0.00030009003,0.00014315132,0.00007453221,0.000013695334,0.000058563568,0.011932796],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980537,0.00068261253,0.0002491094,0.00048243167,0.00021809364,0.00031400713],"domain_scores_gemma":[0.99770457,0.0018204219,0.000107335385,0.00024403012,0.000011733102,0.000111938425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021154883,0.0003066968,0.00048043832,0.000060502764,0.0002729798,0.00018630568,0.0004326836,0.00015603325,0.000108465225],"category_scores_gemma":[0.0021818262,0.00016551728,0.0003012532,0.00024737246,0.00015726067,0.000050135324,0.00021292186,0.00028717332,0.00031926544],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011559727,0.00003529318,2.8126395e-8,0.0010725262,0.00017875744,0.000057690664,0.000062482824,7.56453e-8,0.000020252439,0.09883873,0.007880102,0.8918425],"study_design_scores_gemma":[0.00007503273,0.000017368495,0.0000015783415,0.00092762907,0.00012800228,0.000007966563,0.00000941003,0.000003971654,0.000011799853,0.0049101417,0.99369794,0.00020918545],"about_ca_topic_score_codex":0.0000012907633,"about_ca_topic_score_gemma":0.000010113078,"teacher_disagreement_score":0.9858178,"about_ca_system_score_codex":0.000027354186,"about_ca_system_score_gemma":0.00015271135,"threshold_uncertainty_score":0.6749599},"labels":[],"label_agreement":null},{"id":"W4403241928","doi":"10.1016/j.pnpbp.2024.111166","title":"Associations between cytokine levels and cognitive function among individuals at clinical high risk for psychosis","year":2024,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"National Key Research and Development Program of China; Shanghai Hospital Development Center; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China","keywords":"Psychosis; Cognition; Cytokine; Medicine; Psychology; Clinical psychology; Psychiatry; Internal medicine","score_opus":0.0686872084796659,"score_gpt":0.38469498200129054,"score_spread":0.3160077735216246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403241928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98730433,0.002976532,0.00013000023,0.0031319908,0.0034757406,0.0011801141,0.001494186,0.00021821902,0.000088913075],"genre_scores_gemma":[0.99429816,0.0011616923,0.00022698761,0.0032539659,0.0006461269,0.0003006615,0.00005279249,0.000027594235,0.000032015516],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9965563,0.00078516244,0.0006912118,0.0013012692,0.00014589733,0.00052018755],"domain_scores_gemma":[0.9954469,0.0039824606,0.00023585296,0.00011398011,0.000030540617,0.00019024163],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008093755,0.00032493146,0.00047887847,0.0002140763,0.0003936218,0.00009081105,0.00020332752,0.0005291701,0.00009482588],"category_scores_gemma":[0.0005547472,0.00025320344,0.0001540671,0.00047957065,0.0010788975,0.00016631708,0.0001455561,0.0008222169,0.000017703034],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005311609,0.0003107178,0.9556483,0.00003174731,0.000095673146,0.0000057788548,0.000041163283,2.4553813e-7,0.00010253622,0.0007748968,0.0020683242,0.040389445],"study_design_scores_gemma":[0.0039060523,0.0010773969,0.97826576,0.000042370324,0.00017259487,0.00000605069,0.000017423034,0.000060324328,0.00007703102,0.014164292,0.001914296,0.00029640167],"about_ca_topic_score_codex":0.0000028597703,"about_ca_topic_score_gemma":0.000013821062,"teacher_disagreement_score":0.040093042,"about_ca_system_score_codex":0.000014908332,"about_ca_system_score_gemma":0.000026304728,"threshold_uncertainty_score":0.999992},"labels":[],"label_agreement":null},{"id":"W4403301059","doi":"10.3390/endocrines5040035","title":"The Bidirectional Link between Major Depressive Disorder and Type 2 Diabetes: The Role of Inflammation","year":2024,"lang":"en","type":"article","venue":"Endocrines","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Institut du Savoir Montfort; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Major depressive disorder; Type 2 diabetes; Comorbidity; Insulin resistance; Inflammation; Medicine; Diabetes mellitus; Bioinformatics; Psychology; Clinical psychology; Internal medicine; Endocrinology; Biology; Mood","score_opus":0.010816472136063704,"score_gpt":0.25224681510409097,"score_spread":0.24143034296802726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403301059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883507,0.005875225,0.000007641235,0.0038225679,0.00027417942,0.00013863399,0.000010504378,0.000063174055,0.0014573915],"genre_scores_gemma":[0.9987786,0.00031999446,0.0000070486617,0.000029829405,0.00030325766,0.000018795576,0.0000017966428,0.000008951423,0.0005317598],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945647,0.00005571693,0.00010602067,0.00013853102,0.00012205034,0.000121219615],"domain_scores_gemma":[0.9989509,0.000873602,0.000029176188,0.00011004406,0.000019538502,0.000016762577],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000049956394,0.000066853565,0.00005746426,0.00003196389,0.00018807995,0.0000762982,0.000124412,0.000013850461,0.000020696854],"category_scores_gemma":[0.0003559924,0.00003504461,0.00002788768,0.0002095998,0.00014850593,0.00009260946,0.00005734302,0.0000842569,0.000018042567],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021594424,0.000010914217,0.05170439,0.000068205685,0.00004830744,0.0000030296133,0.000643065,0.000035589517,0.24997884,0.019540023,0.000754654,0.6771914],"study_design_scores_gemma":[0.00022311561,0.000047882906,0.053127885,0.00003745303,0.000021172385,0.000004785209,0.00021142038,0.00122733,0.564196,0.023269687,0.35750976,0.00012349334],"about_ca_topic_score_codex":0.000012561597,"about_ca_topic_score_gemma":0.000016643733,"teacher_disagreement_score":0.6770679,"about_ca_system_score_codex":0.0000034669538,"about_ca_system_score_gemma":0.000016945125,"threshold_uncertainty_score":0.14465779},"labels":[],"label_agreement":null},{"id":"W4403312853","doi":"10.3389/fonc.2024.1466658","title":"Long-term exposure to BAY2416964 reduces proliferation, migration and recapitulates transcriptional changes induced by AHR loss in PyMT-induced mammary tumor cells","year":2024,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Norges Forskningsråd","keywords":"Aryl hydrocarbon receptor; Carcinogenesis; Cell growth; Cancer research; Biology; Knockout mouse; Cell culture; Chemistry; Transcription factor; Receptor; Cancer; Gene; Biochemistry","score_opus":0.019948799369299056,"score_gpt":0.27104027348781085,"score_spread":0.2510914741185118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403312853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98395044,0.0011890162,0.00032213985,0.011404602,0.0021473414,0.0007398107,0.00003108261,0.00008566229,0.00012992568],"genre_scores_gemma":[0.99654305,0.00039663396,0.0007170187,0.0017350579,0.000121398014,0.00020412215,0.000027220365,0.000026076621,0.0002293981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998093,0.0002861061,0.000340979,0.0007055238,0.00019463955,0.000379733],"domain_scores_gemma":[0.9995468,0.0001201632,0.00005404423,0.00014582704,0.000022405173,0.000110734625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000258001,0.00022234724,0.00030651112,0.00052460504,0.00007408838,0.00010938466,0.00023539127,0.00022286888,0.000026556605],"category_scores_gemma":[0.00011060881,0.00022254011,0.00003607877,0.00058044115,0.0000912897,0.0003369607,0.000041103,0.00032230592,0.0000103803295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014915902,0.00018004474,0.007464871,0.00007919726,0.000007733882,0.00015188257,0.003652014,0.000010402902,0.95936304,0.0002460878,0.007025768,0.021669783],"study_design_scores_gemma":[0.0018074549,0.0015370832,0.07243135,0.0001950744,0.00001283645,0.00006957075,0.0006763535,0.0008940607,0.9136955,0.0016583948,0.006406825,0.000615477],"about_ca_topic_score_codex":0.000029062545,"about_ca_topic_score_gemma":0.0009539166,"teacher_disagreement_score":0.06496648,"about_ca_system_score_codex":0.00019993076,"about_ca_system_score_gemma":0.00018668301,"threshold_uncertainty_score":0.9074922},"labels":[],"label_agreement":null},{"id":"W4403541441","doi":"10.1016/j.jad.2024.10.054","title":"Identifying clinical and proteomic markers for early diagnosis and prognosis prediction of major psychiatric disorders","year":2024,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital","funders":"Ministry of Science and ICT, South Korea; Ministry of Health and Welfare","keywords":"Psychiatry; Medicine; Psychology; Clinical psychology","score_opus":0.0251198179747109,"score_gpt":0.315518713189929,"score_spread":0.2903988952152181,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403541441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99045223,0.0026318294,0.0033001914,0.001050481,0.0009394404,0.0014120057,0.000053016163,0.000037488095,0.00012332157],"genre_scores_gemma":[0.99355596,0.005384178,0.0007110325,0.000059185477,0.000106883854,0.00012421046,8.032155e-7,0.00003983788,0.000017910279],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981012,0.00025116373,0.0006505554,0.0004356726,0.0002965281,0.00026488872],"domain_scores_gemma":[0.99811286,0.0012438612,0.00034593255,0.00010243422,0.00006462396,0.00013029875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00075031805,0.00021757536,0.00037290427,0.0004849295,0.00014640717,0.00012998159,0.00016579691,0.00012726578,0.000010735238],"category_scores_gemma":[0.0011681338,0.0001846151,0.000312435,0.0005507589,0.00044093863,0.0005896444,0.000052816584,0.00034533872,0.0000010314434],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091135496,0.0006555553,0.6367211,0.001107803,0.0002820333,0.0000046832033,0.0012248119,0.000010712708,0.008792007,0.00086324225,0.0020463846,0.3473803],"study_design_scores_gemma":[0.0046389853,0.0041195857,0.9594497,0.00048094775,0.0003133922,0.00003419437,0.0010308082,0.0009814287,0.0053888625,0.022291234,0.0009210497,0.0003497937],"about_ca_topic_score_codex":0.000030849707,"about_ca_topic_score_gemma":0.000051951665,"teacher_disagreement_score":0.34703052,"about_ca_system_score_codex":0.000025368954,"about_ca_system_score_gemma":0.00008514632,"threshold_uncertainty_score":0.75283855},"labels":[],"label_agreement":null},{"id":"W4403576648","doi":"10.1186/s13104-024-06963-w","title":"The effect of prebiotic supplementation on serum levels of tryptophan and kynurenine in obese women with major depressive disorder: a double-blinded placebo-controlled randomized clinical trial","year":2024,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"University of Tabriz; Tabriz University of Medical Sciences","keywords":"Placebo; Medicine; Prebiotic; Double blinded; Kynurenine; Randomized controlled trial; Internal medicine; Clinical trial; Major depressive disorder; Kynurenine pathway; Psychiatry; Tryptophan; Physiology; Alternative medicine; Biology; Pathology","score_opus":0.10603258476018157,"score_gpt":0.4308134558763955,"score_spread":0.32478087111621395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403576648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991026,0.00044438618,0.00011019653,0.0005171332,0.00012584336,0.0075659263,0.00004419277,0.000025525065,0.00014082248],"genre_scores_gemma":[0.9984487,0.00017158802,0.00004205179,0.000009477233,0.00006608735,0.0010657021,0.0000019666413,0.000024921883,0.00016945435],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99165714,0.0055148336,0.00081792474,0.000558048,0.00092017016,0.0005319066],"domain_scores_gemma":[0.9397228,0.059646424,0.00016053088,0.000309115,0.0000613463,0.00009981986],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.008933456,0.00020881783,0.00087411166,0.0003821397,0.00015708305,0.00015296525,0.00034062695,0.0001034555,0.00007743324],"category_scores_gemma":[0.014605165,0.00010801388,0.00015706419,0.0007163049,0.0010088978,0.00014091133,0.00011898617,0.00047755826,0.0000045348393],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9815691,0.00019584212,0.0014801255,0.000271015,0.00007498993,0.000009072599,0.00059561786,0.000057588004,0.00667579,0.00071081077,0.000015630472,0.008344386],"study_design_scores_gemma":[0.8731222,0.004654165,0.0027901926,0.00020033175,0.000025130852,0.0000014837784,0.00019271333,0.0024034872,0.11571193,0.00077833753,0.000009728294,0.00011029663],"about_ca_topic_score_codex":0.0000764538,"about_ca_topic_score_gemma":0.00036575235,"teacher_disagreement_score":0.10903613,"about_ca_system_score_codex":0.000038612132,"about_ca_system_score_gemma":0.00023636555,"threshold_uncertainty_score":0.99369526},"labels":[],"label_agreement":null},{"id":"W4403659302","doi":"10.3389/fpsyt.2024.1438002","title":"The association between hematological markers of inflammation and chronic cannabis use: a systematic review and meta-analysis of observational studies","year":2024,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Meta-analysis; Medicine; Observational study; Internal medicine; Cannabis; Subgroup analysis; PsycINFO; Critical appraisal; MEDLINE; CINAHL; Psychiatry; Alternative medicine; Psychological intervention; Pathology; Biology","score_opus":0.12253399944724673,"score_gpt":0.3658224386342174,"score_spread":0.24328843918697063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403659302","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000050695326,0.9966526,0.000018854373,0.001095611,0.00043516723,0.001533308,0.00018804595,0.000013087403,0.00001264347],"genre_scores_gemma":[0.00004865699,0.9989995,0.0002637344,0.00006350241,0.000016516577,0.00028881102,0.000020945967,0.00001537458,0.00028298894],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99662113,0.00089637487,0.0014927932,0.00041526402,0.00039693216,0.00017747919],"domain_scores_gemma":[0.9971653,0.0009684677,0.0014646093,0.00030658225,0.000064065,0.00003096362],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012293892,0.00030083733,0.004787119,0.00037270042,0.00007726166,0.000044911565,0.00024865413,0.00018734773,0.0000038875],"category_scores_gemma":[0.0021533386,0.00016730044,0.0008993703,0.0016118302,0.000182228,0.00011645637,0.00009491592,0.00025631185,6.5973455e-7],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000024279466,0.000012101213,0.00065868325,0.9118149,0.06841766,5.215355e-7,0.000049807557,9.1321664e-7,9.596194e-8,0.0015454121,0.016613008,0.000884444],"study_design_scores_gemma":[0.0001115402,0.000046844543,0.00034877835,0.03369406,0.9504209,0.0000029478815,0.00014332964,0.000038694456,7.1688106e-7,0.0012611295,0.01362802,0.00030304692],"about_ca_topic_score_codex":0.0000037445077,"about_ca_topic_score_gemma":0.000054498483,"teacher_disagreement_score":0.88200325,"about_ca_system_score_codex":0.00016120644,"about_ca_system_score_gemma":0.00016811187,"threshold_uncertainty_score":0.68223137},"labels":[],"label_agreement":null},{"id":"W4403820148","doi":"10.1038/s41398-024-03155-9","title":"Exploring mitochondrial blood-based and genetic markers in older adults with mild cognitive impairment and remitted major depressive disorder","year":2024,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Baycrest Hospital; Health Sciences Centre; Toronto Dementia Research Alliance; University of Toronto; University Health Network; St. Michael's Hospital; Sunnybrook Health Science Centre; Mitel (Canada); Centre for Addiction and Mental Health","funders":"Health Canada; Mitacs; Fondation Brain Canada","keywords":"Cognitive impairment; Psychiatry; Cognition; Schizophrenia spectrum; Schizophrenia (object-oriented programming); Clinical psychology; Major depressive disorder; Medicine; Psychology; Psychosis","score_opus":0.017531546580194877,"score_gpt":0.24135556527823127,"score_spread":0.2238240186980364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403820148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941078,0.002332877,0.00057105557,0.0016973929,0.00031316487,0.0007092549,0.00006409863,0.00006933857,0.0001350124],"genre_scores_gemma":[0.9976087,0.00009691843,0.0016645273,0.0003400414,0.000086446664,0.00014280471,0.0000133642625,0.000030880317,0.000016269556],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99866134,0.00006779319,0.00020074373,0.0005844894,0.0002543181,0.00023128711],"domain_scores_gemma":[0.9995311,0.00026044672,0.000029406363,0.00008043462,0.000014418286,0.00008421395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000029510868,0.00019703295,0.00012738201,0.00018165149,0.00009635692,0.00006523308,0.00006243105,0.000053973057,0.000057015408],"category_scores_gemma":[0.000013071219,0.00017135996,0.00003953991,0.00031642217,0.00014746469,0.00021422352,0.000008825817,0.00018302478,0.000003570875],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02021236,0.0032299922,0.8896214,0.003796513,0.00033591496,0.00046801768,0.015094763,0.0016716731,0.013970036,0.0031802035,0.0006012318,0.04781791],"study_design_scores_gemma":[0.013059469,0.00022429001,0.978792,0.0012111268,0.00007124207,0.000036188983,0.0004991641,0.0037215045,0.0012816626,0.0006913729,0.000029524115,0.00038244558],"about_ca_topic_score_codex":0.00002955557,"about_ca_topic_score_gemma":0.00023293067,"teacher_disagreement_score":0.08917062,"about_ca_system_score_codex":0.0000055464475,"about_ca_system_score_gemma":0.00009899296,"threshold_uncertainty_score":0.69878566},"labels":[],"label_agreement":null},{"id":"W4403839508","doi":"10.3390/biom14111370","title":"Use of Caenorhabditis elegans to Unravel the Tripartite Interaction of Kynurenine Pathway, UPRmt and Microbiome in Parkinson’s Disease","year":2024,"lang":"en","type":"review","venue":"Biomolecules","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Caenorhabditis elegans; Disease; Microbiome; Parkinson's disease; Kynurenine pathway; Biology; Computational biology; Genetics; Neuroscience; Medicine; Kynurenine; Gene","score_opus":0.08008089482802669,"score_gpt":0.32525442707206836,"score_spread":0.24517353224404168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403839508","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009191815,0.9874215,0.000039319395,0.00030697236,0.00042422497,0.0010278275,0.001515793,0.000033264,0.000039248192],"genre_scores_gemma":[0.030144796,0.9691692,0.00004865848,0.00014234081,0.00003803044,0.00007905965,0.000036747235,0.00004897622,0.00029220906],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99830836,0.0002392827,0.0005585679,0.0005059592,0.00016765302,0.00022017225],"domain_scores_gemma":[0.9990508,0.00025083663,0.00022852146,0.00034759403,0.000021239535,0.000101016514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010020862,0.00030100046,0.0006362405,0.000468611,0.00002985493,0.00007248483,0.0002837474,0.00009853229,0.0000138048445],"category_scores_gemma":[0.0002829775,0.00019925054,0.00023934981,0.0009318963,0.00025549287,0.000085831896,0.00016696975,0.00017605003,0.00002175632],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016307317,0.0005016197,0.000019291989,0.01949506,0.00009215067,0.00027147483,0.00095380977,0.0000019707281,0.12530412,0.003067406,0.005286131,0.84484386],"study_design_scores_gemma":[0.00012776861,0.00006790435,0.00008245211,0.0053657494,0.000121519406,0.000022782835,0.000032547556,0.000010844422,0.010004873,0.000038253573,0.98389673,0.00022855474],"about_ca_topic_score_codex":0.00018078818,"about_ca_topic_score_gemma":0.00017726852,"teacher_disagreement_score":0.97861063,"about_ca_system_score_codex":0.000040598814,"about_ca_system_score_gemma":0.00013707197,"threshold_uncertainty_score":0.81252015},"labels":[],"label_agreement":null},{"id":"W4403913316","doi":"10.3389/fpsyt.2024.1451678","title":"The clock is ticking on schizophrenia: a study protocol for a translational study integrating phenotypic, genomic, microbiome and biomolecular data to overcome disability","year":2024,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Dalhousie University","funders":"Università degli Studi di Padova; Ministero della Salute","keywords":"Microbiome; Schizophrenia (object-oriented programming); Protocol (science); Translational research; Phenotype; Computational biology; Neuroscience; Bioinformatics; Medicine; Psychiatry; Biology; Psychology; Data science; Genetics; Computer science; Alternative medicine; Gene; Biotechnology","score_opus":0.04244739867551406,"score_gpt":0.3490317483004572,"score_spread":0.30658434962494313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403913316","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7266536,0.00029455379,0.009639704,0.005783697,0.0047607957,0.25224203,0.00036364218,0.00016756274,0.00009443125],"genre_scores_gemma":[0.92191374,0.0000014688269,0.013472168,0.0010524695,0.00025212436,0.063174166,0.000008891689,0.000074401476,0.000050560157],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99777466,0.0002037049,0.00041228379,0.0010462422,0.00023605028,0.00032704312],"domain_scores_gemma":[0.99892884,0.00020329688,0.00004883338,0.0007254384,0.000011603434,0.0000819684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005854995,0.0002451411,0.00021766168,0.00014364293,0.0003555426,0.0003284367,0.0007150904,0.00005221904,0.000010388924],"category_scores_gemma":[0.00016800038,0.00017878381,0.00006255918,0.0005433298,0.0001381353,0.00016283407,0.00017907085,0.00026302328,0.0000050789704],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.017285002,0.02004511,0.43787912,0.0015531993,0.0007138233,0.0000444042,0.05569338,0.000114144845,0.054730613,0.01029581,0.1672046,0.23444079],"study_design_scores_gemma":[0.06825409,0.014222657,0.4758541,0.0019404105,0.0004190073,0.000051376464,0.08949535,0.070745714,0.003877487,0.09556407,0.1738885,0.005687243],"about_ca_topic_score_codex":0.00001700619,"about_ca_topic_score_gemma":0.00025483777,"teacher_disagreement_score":0.22875355,"about_ca_system_score_codex":0.000058579826,"about_ca_system_score_gemma":0.0001262438,"threshold_uncertainty_score":0.7290592},"labels":[],"label_agreement":null},{"id":"W4404039268","doi":"10.1371/journal.pone.0312227","title":"Correlations between nutritional indicators and cognitive function in patients with stable schizophrenia in a hospital setting","year":2024,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Logistic regression; Montreal Cognitive Assessment; Medicine; Cognition; Internal medicine; Body mass index; Linear regression; Covariate; Cognitive impairment; Psychiatry; Statistics","score_opus":0.014489549002142652,"score_gpt":0.20711050553291804,"score_spread":0.19262095653077538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404039268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99896234,0.000066785564,0.00003048855,0.00015242651,0.000021219234,0.00033912758,0.000107888336,0.00004575494,0.00027397208],"genre_scores_gemma":[0.9997132,0.0000043991777,0.00009420679,0.000044916742,0.000023562054,0.00003545989,0.0000478005,0.000011453318,0.000025008389],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99923635,0.0000376737,0.00011473915,0.0002520568,0.00021765633,0.00014151259],"domain_scores_gemma":[0.99964386,0.00024483463,0.000025470046,0.00003645134,0.0000129163045,0.0000364743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004606672,0.000074571275,0.00008889046,0.0002999719,0.0000550677,0.000048686452,0.00003272505,0.00003955108,0.00002496824],"category_scores_gemma":[0.00015522345,0.00007149711,0.000008757455,0.00061888836,0.00006430661,0.00027134342,0.000022865637,0.00019898037,0.000018218898],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010259998,0.0010214365,0.99555856,0.000056015957,0.000019176188,0.000004681281,0.00035057435,0.000001344754,0.00039348862,0.00037259076,0.000011377761,0.002108143],"study_design_scores_gemma":[0.0015271094,0.00022096961,0.99507034,0.0005068927,0.000023539867,9.401173e-8,0.00007028973,0.00013840616,0.0014816303,0.00085329317,0.000003127291,0.00010428862],"about_ca_topic_score_codex":0.0000047471563,"about_ca_topic_score_gemma":0.000011795832,"teacher_disagreement_score":0.0020038544,"about_ca_system_score_codex":0.000021615078,"about_ca_system_score_gemma":0.000035535923,"threshold_uncertainty_score":0.29155675},"labels":[],"label_agreement":null},{"id":"W4404104696","doi":"10.1038/s41537-024-00528-3","title":"Plasma essential amino acid levels in first episode psychosis at baseline and after antipsychotic treatment","year":2024,"lang":"en","type":"article","venue":"Schizophrenia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Academy of Military Medical Sciences","keywords":"Psychosis; Antipsychotic; Baseline (sea); Schizophrenia (object-oriented programming); Psychology; Internal medicine; Psychiatry; Medicine; Biology","score_opus":0.01985206302866772,"score_gpt":0.2657321966468353,"score_spread":0.24588013361816757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404104696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99574316,0.0009009531,0.00006981276,0.0015972472,0.00077234337,0.00029163956,0.00012778386,0.00014565118,0.00035140046],"genre_scores_gemma":[0.99749535,0.00037690153,0.00034327028,0.0002693588,0.00013748527,0.00009110482,0.000005790166,0.00003980279,0.0012409573],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982148,0.000090602785,0.0002716995,0.00081086915,0.00021156273,0.00040049295],"domain_scores_gemma":[0.9993263,0.0002031232,0.000030498344,0.0003030404,0.000006807943,0.00013026517],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000092498005,0.00028607895,0.00022733142,0.00024298242,0.00011618802,0.00014629381,0.00015253348,0.0000987343,0.000614814],"category_scores_gemma":[0.0000653219,0.00023930636,0.00009795706,0.00044286583,0.0001569281,0.00019304639,0.00006730678,0.00014547836,0.00047832917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010925279,0.002231282,0.04341008,0.0008451967,0.00016267449,0.0029475004,0.004305879,0.000109176945,0.626866,0.004826963,0.011410438,0.29195952],"study_design_scores_gemma":[0.012258661,0.0007182544,0.25358242,0.0006641684,0.00008788598,0.00029809927,0.00005796068,0.012234832,0.6742232,0.0028364935,0.041481216,0.0015568587],"about_ca_topic_score_codex":0.000044784065,"about_ca_topic_score_gemma":0.0030354934,"teacher_disagreement_score":0.29040265,"about_ca_system_score_codex":0.0000808728,"about_ca_system_score_gemma":0.000018867342,"threshold_uncertainty_score":0.97586304},"labels":[],"label_agreement":null},{"id":"W4404125568","doi":"10.1038/s41380-024-02816-x","title":"Evidence of altered monoamine oxidase B, an astroglia marker, in early psychosis and high-risk state","year":2024,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Montreal Neurological Institute and Hospital; University of Toronto; Douglas Mental Health University Institute; McGill University; Douglas College; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund; Government of Canada","keywords":"Psychosis; Monoamine oxidase A; Monoamine oxidase; Monoamine oxidase B; Psychology; Psychiatry; Neuroscience; Biology; Biochemistry; Enzyme","score_opus":0.014245507643530726,"score_gpt":0.2664646109870565,"score_spread":0.25221910334352576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404125568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919717,0.004806961,0.0014061047,0.0006307544,0.00071695814,0.00026017718,0.000041161526,0.00008489064,0.00008132339],"genre_scores_gemma":[0.9964972,0.00053746335,0.0024558844,0.00035510949,0.000032492655,0.00002183363,0.0000016629965,0.000039060244,0.00005928889],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981439,0.0002596615,0.00033344372,0.0006808154,0.00026953482,0.0003126316],"domain_scores_gemma":[0.9992472,0.000090516114,0.00008031353,0.00043786646,0.000014900616,0.00012922238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022041412,0.0002107383,0.00020330938,0.0002518949,0.000042290638,0.0001053644,0.00027740654,0.000056862867,0.000032840424],"category_scores_gemma":[0.00010953836,0.00020446374,0.00007885994,0.0005767196,0.0001326609,0.00032150507,0.00006126072,0.00025975684,0.000018103454],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005704818,0.00056793983,0.07227431,0.00048991904,0.00004129308,0.00015071192,0.0010201926,0.00012937906,0.87129354,0.0034250831,0.00073646335,0.04930066],"study_design_scores_gemma":[0.003314032,0.0022925185,0.68113846,0.002027118,0.00007657742,0.000052876778,0.00026421284,0.0070662913,0.26949698,0.032693002,0.0004049777,0.0011729776],"about_ca_topic_score_codex":0.00032262164,"about_ca_topic_score_gemma":0.00016320689,"teacher_disagreement_score":0.6088641,"about_ca_system_score_codex":0.000013733631,"about_ca_system_score_gemma":0.00004770088,"threshold_uncertainty_score":0.8337789},"labels":[],"label_agreement":null},{"id":"W4404192195","doi":"10.1016/b978-0-443-23565-8.00006-5","title":"Depressive Disorders","year":2024,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Psychology","score_opus":0.01722638819407617,"score_gpt":0.24597637071953796,"score_spread":0.22874998252546178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404192195","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005001082,0.0019476813,0.0000018786262,0.00023646081,0.0010469302,0.0005566456,0.00007969898,0.00035549875,0.9957252],"genre_scores_gemma":[0.005797435,0.0004125554,0.000014736439,0.0012700016,0.00026819968,0.000047150657,0.000006900742,0.00019201776,0.991991],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99797994,0.000021842114,0.00033620393,0.0008171306,0.00043715897,0.00040773491],"domain_scores_gemma":[0.9989212,0.00016015909,0.0001418269,0.00061048375,0.0000177249,0.00014860973],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005636414,0.00053847436,0.00040203732,0.00031561375,0.00013792323,0.00012974782,0.0005531747,0.00034468333,0.0007681346],"category_scores_gemma":[0.00005936583,0.00048252862,0.00039183837,0.00003254058,0.0003661747,0.000050268263,0.0002714052,0.00074110297,0.003696362],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009338355,0.000006818357,3.634646e-7,0.000095576754,0.000025824716,0.00007152419,0.00023196817,7.012679e-7,0.0007956843,0.13732314,0.0008485055,0.8605906],"study_design_scores_gemma":[0.00016082765,0.000031465635,0.0000011984681,0.0002307588,0.00003784052,0.00001425798,0.000008059965,0.0000050136314,0.0014874339,0.2021236,0.7954537,0.000445837],"about_ca_topic_score_codex":2.3107471e-7,"about_ca_topic_score_gemma":0.00002168077,"teacher_disagreement_score":0.86014473,"about_ca_system_score_codex":0.000050465365,"about_ca_system_score_gemma":0.00008595092,"threshold_uncertainty_score":0.99976265},"labels":[],"label_agreement":null},{"id":"W4404296910","doi":"10.1016/j.bbih.2024.100903","title":"Genetic association of the kynurenine pathway to suicidal behavior","year":2024,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Centre Hospitalier Universitaire de Nîmes","keywords":"Kynurenine pathway; Single-nucleotide polymorphism; Kynurenine; Gene; Biology; Genetics; Genotype; Tryptophan","score_opus":0.03374497395227943,"score_gpt":0.3164860709326697,"score_spread":0.2827410969803903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404296910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989998,0.00026109803,0.000040296665,0.0068612765,0.0010145523,0.0012169812,0.00020699303,0.00018137785,0.00021944524],"genre_scores_gemma":[0.9931636,0.000025501055,0.00014953421,0.0032879903,0.00006740908,0.00016331556,0.000008986387,0.00004661576,0.003087088],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9971164,0.00075327395,0.0005300629,0.00040493725,0.0006275455,0.00056778564],"domain_scores_gemma":[0.9984338,0.00046958402,0.00018963341,0.000670707,0.000053179323,0.00018306311],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007195059,0.00022283354,0.0002829224,0.00017959187,0.0003877656,0.000094591356,0.0006628839,0.00012952212,0.00018400088],"category_scores_gemma":[0.00074350974,0.00018235578,0.00019616487,0.0010423429,0.000100136094,0.000114970295,0.00020901048,0.0005632047,0.000090856855],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029891968,0.00096271356,0.025454635,0.0001474678,0.000007539292,0.000024770216,0.00371298,0.000014103097,0.8859856,0.0013662938,0.009074747,0.07321928],"study_design_scores_gemma":[0.00040384658,0.000315888,0.9038821,0.000071480405,0.000023156688,0.000023819877,0.00022736922,0.000018726863,0.08265407,0.00006008364,0.01207537,0.00024410388],"about_ca_topic_score_codex":0.0012279209,"about_ca_topic_score_gemma":0.0007312481,"teacher_disagreement_score":0.87842745,"about_ca_system_score_codex":0.00037615374,"about_ca_system_score_gemma":0.0005457115,"threshold_uncertainty_score":0.74362534},"labels":[],"label_agreement":null},{"id":"W4404365599","doi":"10.3389/fphar.2024.1422693","title":"Bmal1 haploinsufficiency impairs fear memory and modulates neuroinflammation via the 5-HT2C receptor","year":2024,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Shenzhen-Hong Kong Institute of Brain Science","keywords":"Neuroinflammation; Haploinsufficiency; Neuroscience; Fear conditioning; Psychology; Neurotransmitter; Medicine; Biology; Inflammation; Internal medicine; Central nervous system; Phenotype; Amygdala","score_opus":0.011319434277243827,"score_gpt":0.2585523829467175,"score_spread":0.24723294866947368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404365599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824156,0.0018937596,0.0019383021,0.005194506,0.0065794173,0.0005426938,0.000009066547,0.00022366346,0.001202954],"genre_scores_gemma":[0.9969387,0.0006830584,0.00031112717,0.0012561777,0.00016801446,0.00004703607,0.0000020023672,0.000027684258,0.00056619657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99846417,0.0002869381,0.0002359966,0.00048713142,0.00015365133,0.000372094],"domain_scores_gemma":[0.999511,0.00022954207,0.00004518552,0.00013537503,0.000010780769,0.00006808682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002644733,0.00017007513,0.00016327646,0.0002399033,0.00015962437,0.00007348911,0.0002957829,0.00008212519,0.00019363887],"category_scores_gemma":[0.000102356185,0.00013032883,0.00005405277,0.00051980215,0.00039117233,0.00024829575,0.00009639316,0.0003530461,0.00006759695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000109386165,0.000108430424,0.0004936967,0.0000846329,0.000016668073,0.0000884673,0.0022015036,0.00087401725,0.8268063,0.00054171146,0.11052343,0.058151726],"study_design_scores_gemma":[0.0021760094,0.0003963218,0.0063721365,0.00004403967,0.000056706776,0.00013676114,0.0011377702,0.39789283,0.48764136,0.007348114,0.09607809,0.0007198681],"about_ca_topic_score_codex":0.000009138941,"about_ca_topic_score_gemma":0.0000019439344,"teacher_disagreement_score":0.3970188,"about_ca_system_score_codex":0.000054438246,"about_ca_system_score_gemma":0.000050883187,"threshold_uncertainty_score":0.53146553},"labels":[],"label_agreement":null},{"id":"W4404388790","doi":"10.1007/978-1-0716-4200-9","title":"Psychoneuroimmunology","year":2024,"lang":"en","type":"book","venue":"Methods in molecular biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Illinois at Urbana-Champaign; Universidade do Extremo Sul Catarinense; University of Tasmania; Technische Universität München; Health Science Center, University of North Texas; Universidad de Buenos Aires; University of Lethbridge; University of Texas Health Science Center at Houston; University of North Texas; University of Washington; McGovern Medical School; Washington University in St. Louis; Queensland University of Technology; National Institute on Minority Health and Health Disparities; Roswell Park Cancer Institute","keywords":"Psychoneuroimmunology; Psychology; Medicine","score_opus":0.044200040166825716,"score_gpt":0.4096157609277764,"score_spread":0.3654157207609507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404388790","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006646384,0.0074983505,0.19624732,0.0007761757,0.004078101,0.0005100745,0.000041568295,0.0002653035,0.7905166],"genre_scores_gemma":[0.00004803749,0.0010570335,0.24967766,0.007980507,0.00017972129,0.00012409376,0.000044120585,0.00024938435,0.74063945],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9958102,0.0018215248,0.00045882893,0.0012795811,0.00009395619,0.0005359061],"domain_scores_gemma":[0.99836946,0.00073111255,0.00011979362,0.00071485457,0.000013384018,0.000051374172],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005229307,0.0004304798,0.0006147392,0.0006545602,0.000032050604,0.000027610833,0.00078230276,0.00096483197,0.00029099148],"category_scores_gemma":[0.001058445,0.00040618377,0.00025382254,0.00031971958,0.0005656431,0.00001575459,0.0003430504,0.0013502958,0.000634129],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017157929,0.000027369955,8.3513964e-7,0.000046239616,0.000014530853,0.0003584681,0.00003996746,0.0000016532458,0.7917889,0.16884796,0.00402286,0.03483405],"study_design_scores_gemma":[0.00019267183,0.00010420548,0.0000022791742,0.000039317958,0.000009450188,0.000063875916,0.0000023211358,0.000016519976,0.08396588,0.3979804,0.5173274,0.00029569032],"about_ca_topic_score_codex":0.0000034516218,"about_ca_topic_score_gemma":0.0000030431497,"teacher_disagreement_score":0.70782304,"about_ca_system_score_codex":0.000090853886,"about_ca_system_score_gemma":0.0001962602,"threshold_uncertainty_score":0.999839},"labels":[],"label_agreement":null},{"id":"W4404388834","doi":"10.1007/978-1-0716-4200-9_12","title":"The MRL Model: A Valuable Tool in Studies of Autoimmunity-Brain Interactions","year":2024,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Autoimmunity; Cognitive science; Computer science; Neuroscience; Psychology; Medicine; Immunology; Immune system","score_opus":0.20772435678495638,"score_gpt":0.5468747537047711,"score_spread":0.33915039691981475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404388834","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000022184722,0.95925456,0.038464375,0.00034368678,0.0006206261,0.0006372634,0.000020935693,0.00003571645,0.00060064247],"genre_scores_gemma":[0.0000036380218,0.939599,0.059047606,0.00035047365,0.000010931685,0.00035929435,0.000004606504,0.000043083666,0.0005813682],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9907493,0.00730355,0.0008883319,0.0005784003,0.0000939966,0.000386428],"domain_scores_gemma":[0.9939888,0.005088351,0.00023646673,0.00064375217,0.00002646904,0.000016172784],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0027759953,0.00034865184,0.0013059743,0.0005349849,0.000080749414,0.0000246137,0.0007717117,0.00025230923,0.000007047447],"category_scores_gemma":[0.008471688,0.00022014441,0.00040171147,0.0011955062,0.0005505395,0.000029266408,0.0005730695,0.00095626316,0.000009515677],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008860048,0.00008808446,3.3248932e-7,0.0029245894,0.0000986079,0.000044641496,0.00042699784,0.00013485439,0.018225607,0.039905343,0.00039556282,0.9377465],"study_design_scores_gemma":[0.00015652692,0.00007258755,1.2035783e-7,0.0024976153,0.000101485464,0.000034314122,0.00015544024,0.0016650921,0.0018866,0.08564757,0.9074772,0.00030545727],"about_ca_topic_score_codex":0.000019654044,"about_ca_topic_score_gemma":0.0000509949,"teacher_disagreement_score":0.93744105,"about_ca_system_score_codex":0.00012669049,"about_ca_system_score_gemma":0.000216362,"threshold_uncertainty_score":0.9998804},"labels":[],"label_agreement":null},{"id":"W4404416699","doi":"10.1080/13651501.2024.2427617","title":"Lipid variability in drug-naïve individuals affected with Major Depressive Disorder: a systematic review and meta-analysis","year":2024,"lang":"en","type":"review","venue":"International Journal of Psychiatry in Clinical Practice","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Meta-analysis; Psychology; Psychiatry; Major depressive disorder; Drug-naïve; Drug; Clinical psychology; Medicine; Internal medicine; Mood","score_opus":0.08229247367721118,"score_gpt":0.45726018576829547,"score_spread":0.37496771209108426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404416699","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000024800926,0.98759204,0.000112633774,0.009001183,0.0010483091,0.0017103964,0.00014251957,0.000016442757,0.00035165515],"genre_scores_gemma":[0.0004836911,0.9943828,0.0015339102,0.0031129846,0.00019360591,0.00014738072,0.000008478034,0.000046722274,0.000090445974],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9834409,0.008817394,0.005214235,0.00091619184,0.001338743,0.0002725842],"domain_scores_gemma":[0.97323835,0.019973096,0.0056892135,0.000566206,0.00035519098,0.0001779391],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01068074,0.0005797628,0.006446973,0.0010637579,0.00003689806,0.00026724543,0.0014781727,0.00030246307,0.00015768048],"category_scores_gemma":[0.04195466,0.0003419451,0.0026254216,0.0019505399,0.00019706486,0.0007112093,0.000258905,0.0027524403,0.00003576719],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023750665,0.005782031,0.000514007,0.72762877,0.2492173,0.0011568095,0.000234008,0.000023886794,1.048204e-7,0.004119155,0.0023205236,0.008765898],"study_design_scores_gemma":[0.0011379716,0.00019434548,0.00008487543,0.07089604,0.889397,0.0013021798,0.000102357146,0.000012742755,1.1414249e-7,0.0016725061,0.03460327,0.00059657445],"about_ca_topic_score_codex":0.000038443253,"about_ca_topic_score_gemma":0.0002907416,"teacher_disagreement_score":0.65673274,"about_ca_system_score_codex":0.0001152517,"about_ca_system_score_gemma":0.0007752286,"threshold_uncertainty_score":0.99990326},"labels":[],"label_agreement":null},{"id":"W4404464496","doi":"10.3389/fnmol.2024.1450664","title":"Reported race-associated differences in control and schizophrenia post-mortem brain transcriptomes implicate stress-related and neuroimmune pathways","year":2024,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Public Health Ontario; University of Toronto; Mount Sinai Hospital; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; University of Pennsylvania; Krembil Foundation; National Institute of Mental Health; Università degli Studi di Trento; Fondation Brain Canada; Natural Sciences and Engineering Research Council of Canada; University of Pittsburgh; F. Hoffmann-La Roche","keywords":"Dorsolateral prefrontal cortex; Schizophrenia (object-oriented programming); Race (biology); Transcriptome; Prefrontal cortex; Population; Psychology; Biology; Neuroscience; Gene; Gene expression; Genetics; Medicine; Cognition; Psychiatry","score_opus":0.012748674314982784,"score_gpt":0.22731008169725447,"score_spread":0.2145614073822717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404464496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918865,0.0026945379,0.001075676,0.0022772553,0.0009796574,0.00065628544,0.00011253293,0.00022740656,0.000090179616],"genre_scores_gemma":[0.9975524,0.0004946677,0.00008735863,0.0016911502,0.0000051676097,0.000039720282,0.0000059619765,0.000044184166,0.00007942129],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9962147,0.0004794022,0.0006325005,0.0014824051,0.00046941388,0.00072159164],"domain_scores_gemma":[0.99907357,0.00022383017,0.00013463512,0.00036615555,0.00002047607,0.00018136296],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041397696,0.00038869205,0.0005064244,0.0006671044,0.00016900185,0.0003876977,0.0004921581,0.00016063724,0.000003983667],"category_scores_gemma":[0.0014190355,0.0003678671,0.000075661395,0.0017197815,0.0008318303,0.00045359108,0.00011060597,0.0006276929,0.0000016199623],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079162935,0.00011304325,0.011087916,0.00004175668,0.0000059639096,0.0015710277,0.00047105996,0.000033305187,0.9813629,0.0006614223,0.00010362492,0.0044688624],"study_design_scores_gemma":[0.0051746415,0.00055327994,0.8583313,0.00035143617,0.00003963444,0.0003006319,0.0003821055,0.075212725,0.05326755,0.004882623,0.0003706035,0.0011334249],"about_ca_topic_score_codex":0.000059254122,"about_ca_topic_score_gemma":0.000025653771,"teacher_disagreement_score":0.9280953,"about_ca_system_score_codex":0.00004384417,"about_ca_system_score_gemma":0.000115696006,"threshold_uncertainty_score":0.99987733},"labels":[],"label_agreement":null},{"id":"W4404654707","doi":"10.1016/j.bbih.2024.100912","title":"Inflammation biomarkers and neurobehavioral performance in rural adolescents","year":2024,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of Mental Health; National Institutes of Health; Institute of Mental Health, University of British Columbia","keywords":"Inflammation; Medicine; Psychology; Internal medicine","score_opus":0.03331219681292688,"score_gpt":0.3132727445360978,"score_spread":0.2799605477231709,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404654707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99642545,0.00033197246,0.0000073862216,0.0017422938,0.0004238541,0.00072095473,0.000019763762,0.00023565999,0.00009266265],"genre_scores_gemma":[0.9985233,0.0003340037,0.000039530696,0.0008403478,0.000030558724,0.000058393816,0.000018792807,0.000036552647,0.00011850111],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9979778,0.00041632762,0.00042850364,0.0003664282,0.00027594654,0.00053497416],"domain_scores_gemma":[0.9993343,0.000097420445,0.00007744255,0.0003129186,0.000013305878,0.00016462461],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049148686,0.00023003289,0.00021281732,0.0003871001,0.00027331698,0.00016922281,0.00026156567,0.00009273362,0.000032813416],"category_scores_gemma":[0.000104467996,0.00023505536,0.000055333574,0.00070215954,0.00019875831,0.0005584313,0.00012527838,0.00054702366,0.00004498428],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011319479,0.00039038766,0.12071759,0.00062813325,0.0000019910551,0.00007685662,0.0029113342,0.0000066029083,0.18489538,0.00036345673,0.0003146184,0.68958044],"study_design_scores_gemma":[0.0007979592,0.00022976233,0.98957807,0.00049400784,0.000005184834,0.00007079202,0.00042514017,0.00079669885,0.005969642,0.000024268444,0.0013304366,0.00027805057],"about_ca_topic_score_codex":0.0006023715,"about_ca_topic_score_gemma":0.00016271925,"teacher_disagreement_score":0.8688605,"about_ca_system_score_codex":0.0001507851,"about_ca_system_score_gemma":0.00019969128,"threshold_uncertainty_score":0.9585279},"labels":[],"label_agreement":null},{"id":"W4404701256","doi":"10.1186/s13293-024-00671-7","title":"Age- and sex-associated alterations in hypothalamic mitochondrial bioenergetics and inflammatory-associated signaling in the 3xTg mouse model of Alzheimer’s disease","year":2024,"lang":"en","type":"article","venue":"Biology of Sex Differences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research; National Institute of Neurological Disorders and Stroke; Research Manitoba; National Institutes of Health; Alzheimer's Association","keywords":"Bioenergetics; Disease; Human physiology; Neurology; Medicine; Inflammation; Neuroscience; Physiology; Biology; Mitochondrion; Bioinformatics; Immunology; Internal medicine; Genetics","score_opus":0.045599752518309465,"score_gpt":0.2699972926540584,"score_spread":0.22439754013574895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404701256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985866,0.0007340625,0.000012914496,0.00021384246,0.00007379665,0.00019938036,0.00012315885,0.000023373519,0.000032857322],"genre_scores_gemma":[0.99955076,0.00026373586,0.000027122484,0.00007313433,0.000011644812,0.000018645245,0.000012506301,0.000007188554,0.00003525616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880123,0.00030564558,0.00031644615,0.00028928244,0.000101008685,0.00018638771],"domain_scores_gemma":[0.99923307,0.0005368203,0.00008951068,0.00009461718,0.000010828259,0.000035137164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015188126,0.00013294506,0.000237659,0.00017157255,0.00005200038,0.00003339168,0.00016078982,0.000110840025,0.0000032968123],"category_scores_gemma":[0.0003183914,0.00009464212,0.000033955355,0.00019928749,0.00047913127,0.00006484684,0.000049033613,0.00013662553,2.5658264e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026146035,0.00018312322,0.044857062,0.000032069267,0.000024799374,0.000011105422,0.0038599987,0.00022147928,0.94698656,0.003170107,0.000011692132,0.00061585486],"study_design_scores_gemma":[0.0041282973,0.0006706478,0.30176035,0.00050787744,0.00017739783,0.0000031749285,0.0043257396,0.21937886,0.38538778,0.08258076,0.00001748388,0.0010616393],"about_ca_topic_score_codex":0.000066264576,"about_ca_topic_score_gemma":0.00021535059,"teacher_disagreement_score":0.5615988,"about_ca_system_score_codex":0.00000911486,"about_ca_system_score_gemma":0.00005834304,"threshold_uncertainty_score":0.3859394},"labels":[],"label_agreement":null},{"id":"W4404843571","doi":"10.1007/s12035-024-04597-4","title":"Ayahuasca Pretreatment Prevents Sepsis-Induced Anxiety-Like Behavior, Neuroinflammation, and Oxidative Stress, and Increases Brain-Derived Neurotrophic Factor","year":2024,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Neuroinflammation; Oxidative stress; Neuroprotection; Elevated plus maze; Malondialdehyde; Medicine; Myeloperoxidase; Pharmacology; Lipid peroxidation; Endocrinology; Internal medicine; Inflammation; Anxiety","score_opus":0.016097865768634825,"score_gpt":0.25889454046666344,"score_spread":0.24279667469802863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404843571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99701345,0.00032621986,0.00007365162,0.0008036408,0.0003092588,0.00096858665,0.00014277177,0.00025916274,0.00010326403],"genre_scores_gemma":[0.99725133,0.00034747127,0.000045948196,0.0020266746,0.00002806831,0.000114446484,0.000033973363,0.00006503429,0.000087059685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972399,0.0006737571,0.00030685525,0.0011672181,0.00016555455,0.0004467344],"domain_scores_gemma":[0.9989909,0.0003422683,0.0000910219,0.00036871227,0.000024962523,0.00018212259],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00004642558,0.00041283897,0.0003054143,0.000194659,0.00017777074,0.0001666128,0.00022102622,0.00014806469,0.000050121354],"category_scores_gemma":[0.00029973683,0.0003746558,0.0000986975,0.0002937749,0.00028361857,0.00020565874,0.0002655736,0.00029995566,0.000023044004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003712866,0.00015144545,0.0011659128,0.00006459914,0.000020363586,0.0003841572,0.00015622281,0.0000054898323,0.99575657,0.0004730497,0.00008143009,0.001703654],"study_design_scores_gemma":[0.0009959671,0.0009678434,0.05735513,0.000062663836,0.00006673257,0.0003369393,0.000023908624,0.00024493254,0.93794614,0.00041157246,0.0011062319,0.00048195847],"about_ca_topic_score_codex":0.000036742847,"about_ca_topic_score_gemma":0.000012399382,"teacher_disagreement_score":0.057810422,"about_ca_system_score_codex":0.000022874057,"about_ca_system_score_gemma":0.000061213876,"threshold_uncertainty_score":0.99987054},"labels":[],"label_agreement":null},{"id":"W4404871081","doi":"10.1016/b978-0-443-18979-1.00002-2","title":"Multifactorial microbial networks shape aging and neurodegeneration","year":2024,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina","funders":"","keywords":"Neurodegeneration; Neuroscience; Biology; Medicine; Disease; Pathology","score_opus":0.019573922554874765,"score_gpt":0.23590532282726256,"score_spread":0.21633140027238779,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404871081","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0019385102,0.001119456,0.000012648059,0.00013243864,0.0054015927,0.000602292,0.000048808783,0.0002604018,0.9904839],"genre_scores_gemma":[0.028140035,0.00021863637,0.00004487345,0.0011375867,0.0027567756,0.000013490364,0.000017668512,0.00015239867,0.9675185],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981749,0.000034113815,0.00033792402,0.0008919551,0.000238172,0.00032292615],"domain_scores_gemma":[0.9993247,0.00011528869,0.00012195187,0.00029810172,0.000022577853,0.00011738889],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008840626,0.00044931288,0.00033371412,0.00015017577,0.00017817848,0.000287792,0.00021828376,0.0003269148,0.00016483775],"category_scores_gemma":[0.000037687336,0.0004308224,0.00016243664,0.00001885747,0.00019515395,0.00006600157,0.00020633196,0.00068385585,0.00015990385],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022024666,0.000005160141,6.95409e-7,0.00007045652,0.0000142367835,0.000070679096,0.0001560574,0.000015445,0.02877111,0.010503112,0.00040945987,0.95996153],"study_design_scores_gemma":[0.0003940429,0.000044920325,0.0000041600733,0.000212074,0.00004900083,0.000037242877,0.0000018818231,0.001697163,0.0042383736,0.0034809227,0.98929054,0.00054967694],"about_ca_topic_score_codex":4.1986146e-7,"about_ca_topic_score_gemma":0.000021011021,"teacher_disagreement_score":0.98888105,"about_ca_system_score_codex":0.000037496473,"about_ca_system_score_gemma":0.000048386555,"threshold_uncertainty_score":0.99981433},"labels":[],"label_agreement":null},{"id":"W4404876981","doi":"10.1016/j.psychres.2024.116307","title":"Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort","year":2024,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Qatar National Library; Medical Research Council; Hamad Medical Corporation","keywords":"Schizophrenia (object-oriented programming); Cohort; Peripheral; Medicine; Inflammation; Peripheral blood; Immunology; Internal medicine; Psychiatry","score_opus":0.023336667716458495,"score_gpt":0.3116119909071031,"score_spread":0.28827532319064464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404876981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97615707,0.01687985,0.0000056433714,0.0017661647,0.0009509674,0.0007172219,0.00005919571,0.00014119683,0.003322701],"genre_scores_gemma":[0.997133,0.0016546678,0.00022415745,0.000121701785,0.0002468564,0.00013652924,0.000015127806,0.000053675216,0.0004142731],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9963757,0.00068731385,0.00035215158,0.0011073953,0.0007954489,0.00068200624],"domain_scores_gemma":[0.9989147,0.0003070626,0.000029710836,0.00045072654,0.00002899142,0.0002687764],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003657913,0.00029449636,0.0002932581,0.0007692195,0.0003155848,0.0004800082,0.00037851656,0.00016401643,0.00040108478],"category_scores_gemma":[0.00015901405,0.0002453881,0.00012725325,0.0011797715,0.0005470346,0.00035684835,0.00016075351,0.00053523324,0.00020239518],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013671747,0.0014668845,0.12730987,0.00041430996,0.0012657206,0.0025677797,0.003318424,0.00002901964,0.7126662,0.073713794,0.009235268,0.054340996],"study_design_scores_gemma":[0.009020753,0.0011138174,0.8559803,0.00043720612,0.00011269171,0.000091087386,0.0032484632,0.005892156,0.010079775,0.058192603,0.054441236,0.001389922],"about_ca_topic_score_codex":0.002127573,"about_ca_topic_score_gemma":0.0021145183,"teacher_disagreement_score":0.7286704,"about_ca_system_score_codex":0.00017109766,"about_ca_system_score_gemma":0.00064547674,"threshold_uncertainty_score":0.9999998},"labels":[],"label_agreement":null},{"id":"W4404965677","doi":"10.1503/jpn-240038","title":"The amino acid metabolism pathway of peripheral T lymphocytes and ketamine-induced schizophrenia-like phenotype","year":2024,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Sichuan University","keywords":"Metabolomics; Metabolite; Flow cytometry; Immune system; Schizophrenia (object-oriented programming); Peripheral; Amino acid; Biology; Metabolism; Metabolic pathway; Metabolome; Chemistry; Biochemistry; Medicine; Immunology; Bioinformatics; Internal medicine","score_opus":0.017942652349560717,"score_gpt":0.25434766145303966,"score_spread":0.23640500910347895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404965677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98249507,0.010402237,0.00008443566,0.0017901316,0.0049030283,0.00008583635,0.0000074189006,0.000021076816,0.00021078615],"genre_scores_gemma":[0.996594,0.0019736725,0.00024916686,0.000808699,0.00021482138,0.0000014102965,4.1012687e-8,0.000013818877,0.00014436977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840283,0.0001399169,0.0004233663,0.00033591737,0.00042648258,0.00027147945],"domain_scores_gemma":[0.999183,0.00021832803,0.00022868543,0.00018154088,0.000040053368,0.00014836363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003891594,0.00017782477,0.00022757163,0.00013718182,0.00035947957,0.00027897913,0.00043390645,0.00005029088,0.000006350321],"category_scores_gemma":[0.00031584981,0.00010876615,0.000109788,0.0005470032,0.000551429,0.00050918426,0.00008919774,0.0002837756,0.0000012312179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016398652,0.000060630504,0.00020658909,0.00004884545,0.000004005314,0.000021703267,0.00022569948,0.000004800279,0.96853715,0.0146745555,0.00015846675,0.015893558],"study_design_scores_gemma":[0.0037872614,0.0021886476,0.078784436,0.0004021792,0.00010147411,0.0028640893,0.0009274883,0.0034823075,0.8518513,0.017589819,0.03720838,0.0008126399],"about_ca_topic_score_codex":0.0000024735984,"about_ca_topic_score_gemma":0.000006738707,"teacher_disagreement_score":0.11668588,"about_ca_system_score_codex":0.000009019393,"about_ca_system_score_gemma":0.00028920904,"threshold_uncertainty_score":0.4435355},"labels":[],"label_agreement":null},{"id":"W4405219562","doi":"10.1093/brain/awae343","title":"Extra-axial inflammatory signal and its relationship to peripheral and central immunity in depression","year":2024,"lang":"en","type":"article","venue":"Brain","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Janssen Biotech; Janssen Canada; NIHR Cambridge Biomedical Research Centre; Medical Research Council; GlaxoSmithKline España; King's College London; Department of Health and Social Care; National Institute for Health and Care Research; University of Cambridge; King’s College London; NIHR Oxford Biomedical Research Centre; Wellcome Trust; GlaxoSmithKline; H. Lundbeck A/S; Pfizer","keywords":"Skull; Peripheral; Immunity; Immune system; Bone marrow; Central nervous system; Medicine; Inflammation; Pathology; Immunology; Internal medicine; Anatomy","score_opus":0.026951163566733268,"score_gpt":0.27056484148836957,"score_spread":0.2436136779216363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405219562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99716556,0.00059589173,0.000073856776,0.0009036527,0.00010876784,0.00018961709,0.0000065962217,0.00006623701,0.00088979537],"genre_scores_gemma":[0.9988984,0.000012778857,0.00004001778,0.0005136821,0.000045475877,0.0000109856055,0.0000011668945,0.000011220122,0.00046627613],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99915534,0.00014685954,0.00012213009,0.000258414,0.000108597764,0.0002086661],"domain_scores_gemma":[0.9994518,0.00035929473,0.000011275602,0.00007296091,0.000003885609,0.000100769605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012544359,0.000090406276,0.00007377283,0.00010214098,0.00009734618,0.00009697968,0.00007485427,0.000059145717,0.00008108745],"category_scores_gemma":[0.00044597618,0.000084781095,0.000017588167,0.00018956575,0.000048469465,0.00021078066,0.00006789013,0.00019887865,0.00001458139],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012681421,0.00005062713,0.033760276,0.00011432624,0.0000026754212,0.00011561043,0.006688518,0.000105456966,0.91917795,0.0125280265,0.0017285979,0.025601134],"study_design_scores_gemma":[0.0005721035,0.000050947132,0.9638596,0.00011949168,0.000002016366,0.00003129439,0.00020555811,0.004069943,0.023413314,0.001925575,0.0055288346,0.0002212834],"about_ca_topic_score_codex":0.00001288501,"about_ca_topic_score_gemma":0.000060092163,"teacher_disagreement_score":0.93009937,"about_ca_system_score_codex":0.000022606446,"about_ca_system_score_gemma":0.000037376623,"threshold_uncertainty_score":0.34572726},"labels":[],"label_agreement":null},{"id":"W4405368058","doi":"10.1158/1078-0432.ccr-24-0439","title":"Phase 1/2 Study of the Indoleamine 2,3-Dioxygenase 1 Inhibitor Linrodostat Mesylate Combined with Nivolumab or Nivolumab and Ipilimumab in Advanced Solid Tumors or Hematologic Malignancies","year":2024,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Princess Margaret Cancer Centre; University Health Network; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Nivolumab; Ipilimumab; Medicine; Pharmacodynamics; Adverse effect; Mesylate; Internal medicine; Pharmacology; Oncology; Pharmacokinetics; Melanoma; Cancer; Immunotherapy; Cancer research; Chemistry","score_opus":0.16615465021824888,"score_gpt":0.47784201619372335,"score_spread":0.3116873659754745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405368058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995708,0.00072104076,0.0000023421326,0.00093186134,0.00029224422,0.0021338689,0.000056599976,0.000086206375,0.00006784301],"genre_scores_gemma":[0.9969902,0.000596264,0.000024916446,0.00020195672,0.00007293095,0.00033514216,0.000001275786,0.000054174914,0.0017231152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99479395,0.0012318816,0.001016026,0.0011462593,0.0010346522,0.0007772332],"domain_scores_gemma":[0.9952317,0.0035468258,0.0001511641,0.00068803213,0.0001696306,0.00021263336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015622985,0.0002968954,0.00075477734,0.00030102566,0.00025841294,0.00013288716,0.00073626154,0.00013677753,0.00016081841],"category_scores_gemma":[0.003967602,0.00015652183,0.00009561919,0.0024560662,0.0014947176,0.00024250936,0.00057365594,0.0012569712,0.000014229167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.30343416,0.060850214,0.02860822,0.0063421475,0.00046844935,0.01246068,0.022505416,0.00054649357,0.38373587,0.001489849,0.0142039545,0.16535456],"study_design_scores_gemma":[0.13519062,0.0961205,0.029576737,0.005358937,0.00006239421,0.0002121231,0.024084998,0.005743403,0.6973561,0.0015749527,0.002957208,0.0017620414],"about_ca_topic_score_codex":0.00019111033,"about_ca_topic_score_gemma":0.0037376331,"teacher_disagreement_score":0.31362024,"about_ca_system_score_codex":0.00011319,"about_ca_system_score_gemma":0.0010052109,"threshold_uncertainty_score":0.6382775},"labels":[],"label_agreement":null},{"id":"W4405385067","doi":"10.1101/2024.12.11.24317786","title":"The genetic landscape of kynurenine predicts neurovascular pathology and disrupted white matter integrity in patients with mood disorders","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Ministero della Salute","keywords":"Bipolar disorder; Hyperintensity; Mood disorders; Internal medicine; Kynurenine; Psychology; White matter; Endocrinology; Major depressive disorder; Mood; Medicine; Psychiatry; Biology; Genetics; Magnetic resonance imaging","score_opus":0.007407911514344289,"score_gpt":0.2148735007227889,"score_spread":0.20746558920844463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405385067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99687433,0.00032772621,0.000034588706,0.0009865719,0.0004191206,0.00067287736,0.00006678246,0.00004899697,0.00056902703],"genre_scores_gemma":[0.99933106,0.00024493152,0.000053173237,0.00013463998,0.000021012267,0.00006939509,0.000014284426,0.00004858111,0.00008291922],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99778277,0.00033028054,0.00037561927,0.0008109022,0.00035779935,0.00034262615],"domain_scores_gemma":[0.99894196,0.00016521757,0.00014880241,0.0006427475,0.00003198824,0.00006930912],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018082326,0.00032570303,0.00036036692,0.00017675347,0.000062192456,0.00007078108,0.00047293265,0.00018888958,0.00003524136],"category_scores_gemma":[0.00020913598,0.00020128881,0.000091645954,0.00031463132,0.000417541,0.000031580952,0.00080090185,0.0010209507,0.000013528249],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010197501,0.0001354863,0.99764043,0.0002142684,0.000015214421,0.000019465486,0.00043231752,0.0000838562,0.00017822075,0.00003414211,0.0000968946,0.001047744],"study_design_scores_gemma":[0.00095005817,0.00014688335,0.99590325,0.00011763336,0.00003059451,0.000005957529,0.000033098833,0.0004778432,0.0002718203,0.0017803585,0.00007521669,0.00020730088],"about_ca_topic_score_codex":0.000017326016,"about_ca_topic_score_gemma":0.00035280813,"teacher_disagreement_score":0.0024567544,"about_ca_system_score_codex":0.000010401838,"about_ca_system_score_gemma":0.000041628344,"threshold_uncertainty_score":0.82083195},"labels":[],"label_agreement":null},{"id":"W4405587016","doi":"10.1016/j.pnpbp.2024.111227","title":"Role of depression, suicide attempt history and childhood trauma in neutrophil-to-lymphocyte ratio dynamics: A 30-week prospective study","year":2024,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Agence Nationale de la Recherche","keywords":"Mood; Mood disorders; Depression (economics); Confounding; Medicine; Clinical psychology; Biomarker; Prospective cohort study; Suicide attempt; Internal medicine; Psychiatry; Poison control; Psychology; Anxiety; Injury prevention; Emergency medicine; Biology","score_opus":0.01837438120829125,"score_gpt":0.2971721203621136,"score_spread":0.27879773915382233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405587016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97671497,0.018932544,0.0000036357064,0.00087438204,0.0012296847,0.001759484,0.000022302791,0.00012193259,0.00034109177],"genre_scores_gemma":[0.9972382,0.00050866586,0.00008019857,0.0016616008,0.00010175596,0.00036860505,0.0000019756462,0.000027080247,0.00001188885],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9969337,0.0005264406,0.00056946935,0.0013344708,0.00016054793,0.0004754011],"domain_scores_gemma":[0.99915797,0.00035880526,0.000107475826,0.00019903197,0.000018663732,0.0001580696],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027420442,0.0003531856,0.00046430813,0.00042248916,0.00008624233,0.000032230182,0.00034480516,0.00021705925,0.00008008278],"category_scores_gemma":[0.000089381945,0.00027527413,0.00006956785,0.0005684316,0.00059469946,0.00013233408,0.00018186099,0.0006413081,0.000009028689],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013799821,0.0030319535,0.96569914,0.00006136165,0.000019983678,0.00010373872,0.0010814334,0.000009304851,0.004565837,0.0012527157,0.0001440668,0.022650506],"study_design_scores_gemma":[0.003896006,0.0016982303,0.98914725,0.00007258901,0.000015900441,0.000046938767,0.00038016407,0.0006301182,0.00026827166,0.003353072,0.00019484248,0.00029659565],"about_ca_topic_score_codex":0.0000115537,"about_ca_topic_score_gemma":0.00006662046,"teacher_disagreement_score":0.023448154,"about_ca_system_score_codex":0.00008518961,"about_ca_system_score_gemma":0.000083422376,"threshold_uncertainty_score":0.99996996},"labels":[],"label_agreement":null},{"id":"W4405782171","doi":"10.3390/biom15010010","title":"The Role of Neuroglia in the Development and Progression of Schizophrenia","year":2024,"lang":"en","type":"review","venue":"Biomolecules","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"University of Alberta; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Schizophrenia (object-oriented programming); Neuroglia; Neuroscience; Psychology; Medicine; Psychiatry; Central nervous system","score_opus":0.036222578990790795,"score_gpt":0.33148027792262935,"score_spread":0.29525769893183856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405782171","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016351903,0.99732023,8.1372593e-7,0.00004562224,0.00007054401,0.0004355099,0.0000103572465,0.00001137533,0.00047037812],"genre_scores_gemma":[0.0067293053,0.99305016,0.00009215415,0.0000147327655,0.000012178587,0.000057431065,0.0000020722407,0.000017958842,0.000023997065],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987714,0.00022663378,0.00037197897,0.00025463893,0.0002334361,0.00014191169],"domain_scores_gemma":[0.9993467,0.00024029678,0.00016669979,0.00022081648,0.000007812225,0.000017707318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019864787,0.00017417017,0.0003154204,0.00010259521,0.00005953128,0.000044568045,0.00045934855,0.00007088879,7.874555e-7],"category_scores_gemma":[0.00014198101,0.000075617565,0.0000953038,0.00043062176,0.00031179335,0.000016524871,0.00015132893,0.00014746212,0.0000075557837],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005892053,0.00003007465,6.9857754e-7,0.0016659528,0.000004972025,0.0000066401444,0.00018463634,4.869777e-9,0.0012227022,0.0043633226,0.000034965622,0.99248016],"study_design_scores_gemma":[0.000078418205,0.00003959454,0.0000152158755,0.0033862686,0.00003535,0.000016131302,0.00011179433,0.000002788014,0.014639577,0.0005010828,0.98106325,0.0001105162],"about_ca_topic_score_codex":0.0000022587583,"about_ca_topic_score_gemma":0.000011704655,"teacher_disagreement_score":0.9923696,"about_ca_system_score_codex":0.0000066188836,"about_ca_system_score_gemma":0.0001371395,"threshold_uncertainty_score":0.30835947},"labels":[],"label_agreement":null},{"id":"W4405901833","doi":"10.1101/2024.12.30.630684","title":"Astrocyte-derived extracellular matrix proteins regulate synapse remodeling in stress-induced depression","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Extracellular matrix; Astrocyte; Synapse; Neuroscience; Depression (economics); Cell biology; Extracellular; Biology; Central nervous system; Economics","score_opus":0.020799428926313562,"score_gpt":0.2439663209737858,"score_spread":0.22316689204747223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405901833","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913118,0.0033903853,0.000824508,0.000248396,0.0011327142,0.00189294,0.00017449546,0.0010113354,0.000013457185],"genre_scores_gemma":[0.99616665,0.00021200975,0.002564464,0.000071945055,0.0002996274,0.00036230413,4.0110777e-7,0.00029204582,0.000030582392],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.994179,0.0004093481,0.0010097144,0.002524183,0.0007874876,0.0010902691],"domain_scores_gemma":[0.99707204,0.00011983711,0.0004880685,0.0018256475,0.00014450378,0.0003498892],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00060959987,0.00094712904,0.0008219346,0.0007856276,0.00021564266,0.00052766374,0.0010814685,0.00094303995,0.00005813954],"category_scores_gemma":[0.00075008156,0.0009876016,0.00028958116,0.0010113042,0.00014707728,0.00024099808,0.0015739611,0.002285359,0.00019439532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009093889,0.00019352276,0.0003504732,0.00081103423,0.000022625154,0.00046454323,0.000029684832,0.0016223674,0.99588525,0.00049433537,0.000025763595,0.000009452475],"study_design_scores_gemma":[0.0007224277,0.0000428368,0.00475899,0.00225666,0.00004002918,7.8293645e-8,0.000008561297,0.009865417,0.9810693,0.000038903207,0.00018506129,0.0010117362],"about_ca_topic_score_codex":0.00008297256,"about_ca_topic_score_gemma":0.000013649798,"teacher_disagreement_score":0.014815959,"about_ca_system_score_codex":0.00038095203,"about_ca_system_score_gemma":0.0006791801,"threshold_uncertainty_score":0.99925745},"labels":[],"label_agreement":null},{"id":"W4406002727","doi":"10.1186/s12888-024-06407-6","title":"Effect of phototherapy on event-related potentials in patients with post-stroke depression through serum tetrahydrobiopterin level intervention: a clinical study","year":2025,"lang":"en","type":"article","venue":"BMC Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Health Commission of Hebei Province","keywords":"Montreal Cognitive Assessment; Medicine; Depression (economics); Internal medicine; Tetrahydrobiopterin; Stroke (engine); Post-stroke depression; Cognition; Gastroenterology; Anesthesia; Psychology; Cognitive impairment; Psychiatry; Nitric oxide; Hippocampus; Nitric oxide synthase","score_opus":0.016877903379278292,"score_gpt":0.3304995168835982,"score_spread":0.3136216135043199,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406002727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99604017,0.000060724946,0.00018985823,0.000055058368,0.0015302516,0.0015325994,0.00007134562,0.000052674604,0.0004673095],"genre_scores_gemma":[0.99907875,0.0000051126403,0.00014408786,0.00032072695,0.000015326534,0.00004025058,0.000005242331,0.000021594024,0.00036889312],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99724126,0.000907468,0.00071064755,0.0006041177,0.0002943962,0.00024211017],"domain_scores_gemma":[0.99904907,0.00019781555,0.000249245,0.00043825564,0.000026932294,0.00003868212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004216262,0.00023893478,0.00038991403,0.00018297129,0.000071225906,0.000023936147,0.0003309226,0.00013069838,0.00008738427],"category_scores_gemma":[0.00015622734,0.0001739724,0.00021453948,0.00045734484,0.00009239737,0.00012885536,0.000067523964,0.00027748456,0.000015255812],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044032778,0.0052418048,0.9828628,0.0001057076,0.000037233196,9.052203e-7,0.000086310625,0.00004200068,0.0017510275,0.000045785262,0.000067353874,0.005355808],"study_design_scores_gemma":[0.018956456,0.0062090643,0.96169525,0.00048220306,0.000022958278,5.760034e-7,0.000100465724,0.000028993076,0.012235783,0.00008082657,0.000018344956,0.00016910212],"about_ca_topic_score_codex":0.000041756197,"about_ca_topic_score_gemma":0.00016576705,"teacher_disagreement_score":0.021167558,"about_ca_system_score_codex":0.00002081259,"about_ca_system_score_gemma":0.00006530302,"threshold_uncertainty_score":0.70943886},"labels":[],"label_agreement":null},{"id":"W4406163123","doi":"10.1007/978-3-031-72079-6_12","title":"Psychoneuroimmunology and Allostatic Load in Schizophrenia: Insights from Social and Biomedical Perspectives","year":2024,"lang":"en","type":"book-chapter","venue":"Integrated science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institut Universitaire en Santé Mentale de Québec; Canadian Institute for International Peace and Security","funders":"","keywords":"Allostatic load; Psychoneuroimmunology; Allostasis; Schizophrenia (object-oriented programming); Psychology; Neuroscience; Medicine; Psychiatry","score_opus":0.02407809307283032,"score_gpt":0.2751629845478545,"score_spread":0.25108489147502416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406163123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8194447,0.009901944,0.000029961171,0.0031524578,0.0014463393,0.0005692341,0.00021027548,0.00026713996,0.16497797],"genre_scores_gemma":[0.98075026,0.0011268886,0.00010412678,0.0003998079,0.00007443263,0.000009333761,0.000005036935,0.000041188265,0.017488938],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9973572,0.000041875257,0.0003051698,0.001390387,0.0005670876,0.00033830287],"domain_scores_gemma":[0.9992551,0.00025361814,0.000090963535,0.00020734574,0.00006876199,0.00012416052],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0001210491,0.00036041075,0.00037194113,0.0007025191,0.00022978595,0.00025131254,0.0005039012,0.00029209175,0.00011183552],"category_scores_gemma":[0.00044693434,0.00028940086,0.000047723395,0.00049141794,0.006576664,0.00022535062,0.00024483653,0.0010519248,0.00011251588],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022629155,0.000097293145,0.000004348976,0.000033876422,0.00002056626,0.0005423231,0.014591473,1.5944731e-7,0.44436422,0.52423465,0.00052473583,0.015360047],"study_design_scores_gemma":[0.0035029992,0.0007790969,0.003537862,0.0011783587,0.00006493116,0.0002477821,0.0064271437,0.0011993934,0.007132931,0.9107722,0.06312218,0.0020351207],"about_ca_topic_score_codex":0.0001442871,"about_ca_topic_score_gemma":0.00020837288,"teacher_disagreement_score":0.4372313,"about_ca_system_score_codex":0.00015569408,"about_ca_system_score_gemma":0.0005060097,"threshold_uncertainty_score":0.99995583},"labels":[],"label_agreement":null},{"id":"W4406200932","doi":"10.1002/alz.093072","title":"Inflammation in the white matter relates to core Alzheimer's disease pathophysiological processes","year":2024,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill Genome Centre; McGill University; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Pathophysiology; White matter; Inflammation; Disease; Neuroscience; Medicine; Core (optical fiber); Alzheimer's disease; Psychology; Pathology; Immunology; Magnetic resonance imaging; Physics","score_opus":0.03910315396219629,"score_gpt":0.28061583481300667,"score_spread":0.24151268085081037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406200932","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9248909,0.05160435,0.000102569305,0.017656954,0.00062867807,0.0015009323,0.00004308223,0.0003324471,0.0032401239],"genre_scores_gemma":[0.9950153,0.00006020963,0.000099136574,0.0044887555,0.000100102625,0.00018316193,0.000016046033,0.000021914437,0.00001535736],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99852484,0.00011728731,0.00025381916,0.0005068249,0.00027786402,0.00031933252],"domain_scores_gemma":[0.99939686,0.00017793407,0.00003694635,0.00027800773,0.000020455345,0.00008981348],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014432169,0.0001904418,0.00011364958,0.000110226276,0.0001179605,0.00021019977,0.00040569616,0.00005150243,0.00042212024],"category_scores_gemma":[0.00011325752,0.000125281,0.000063789215,0.0007039225,0.0000849221,0.00030421716,0.000105662315,0.00017634268,0.0015154403],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012745018,0.0018858685,0.09938096,0.0005015773,0.0044719875,0.0024327603,0.03739614,0.002782874,0.34212694,0.036574088,0.21184564,0.25932667],"study_design_scores_gemma":[0.0012873678,0.0004915934,0.69360435,0.0004954578,0.007221233,0.000040863903,0.0012520141,0.0026267497,0.13533437,0.0391728,0.1162222,0.0022510227],"about_ca_topic_score_codex":0.000004979731,"about_ca_topic_score_gemma":0.0000118369635,"teacher_disagreement_score":0.5942234,"about_ca_system_score_codex":0.0000026214973,"about_ca_system_score_gemma":0.000050288396,"threshold_uncertainty_score":0.999262},"labels":[],"label_agreement":null},{"id":"W4406212890","doi":"10.1016/j.bpsgos.2025.100448","title":"A Transcriptomic Signature of Depressive Symptoms in Late Life","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry Global Open Science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto; Centre for Addiction and Mental Health","funders":"National Institutes of Health; Krembil Foundation; Canadian Institutes of Health Research; National Institute on Aging; MAP Fund; Centre for Addiction and Mental Health Foundation","keywords":"Signature (topology); Transcriptome; Depressive symptoms; Computational biology; Psychology; Biology; Computer science; Genetics; Neuroscience; Gene; Mathematics; Cognition; Gene expression","score_opus":0.0270041961039515,"score_gpt":0.3212990240520143,"score_spread":0.29429482794806283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406212890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9620582,0.0005266499,0.00011160355,0.0018937002,0.000911961,0.00056809076,0.00004522171,0.000038689188,0.03384588],"genre_scores_gemma":[0.9933103,0.00003717643,0.00038886504,0.006166873,0.000012148653,0.00001794354,7.072318e-7,0.0000023882315,0.00006364132],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99787194,0.0001343688,0.00037099954,0.0008834834,0.00027075713,0.00046844885],"domain_scores_gemma":[0.9992583,0.0000873844,0.00011488228,0.0003597917,0.00003779548,0.00014187687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036967784,0.00017791492,0.0002996214,0.00010782648,0.00016154854,0.00012375775,0.0034896855,0.00015084629,0.000067051726],"category_scores_gemma":[0.00094626396,0.0001251261,0.00008307187,0.0029350324,0.0012499352,0.00032548342,0.00055964495,0.00019605334,0.000017060167],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006895641,0.0009850475,0.19284895,0.00003454614,0.000009823395,0.000010891637,0.00012035616,0.00039422812,0.42826444,0.3680761,0.0018139776,0.0067520896],"study_design_scores_gemma":[0.0030775536,0.00037656116,0.86745703,0.00019102734,0.0000071237714,0.0000040753985,0.00017396823,0.0006071804,0.020894606,0.105256595,0.0014823254,0.00047196998],"about_ca_topic_score_codex":0.000063633786,"about_ca_topic_score_gemma":0.000050134204,"teacher_disagreement_score":0.67460805,"about_ca_system_score_codex":0.00005796917,"about_ca_system_score_gemma":0.0006270162,"threshold_uncertainty_score":0.6484762},"labels":[],"label_agreement":null},{"id":"W4406222657","doi":"10.1002/alz.095723","title":"Association of later‐life emergent affective dysregulation with neuroinflammatory biomarkers in dementia‐free older adults","year":2024,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"","keywords":"Dementia; Association (psychology); Psychology; Neuroinflammation; Medicine; Psychiatry; Clinical psychology; Gerontology; Disease; Psychotherapist; Internal medicine","score_opus":0.011027225624701957,"score_gpt":0.2323047039834802,"score_spread":0.22127747835877823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406222657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862228,0.010361899,0.0001669729,0.0007952516,0.00065078045,0.00075049046,0.000021612412,0.00014524773,0.00088492053],"genre_scores_gemma":[0.9994877,0.000068749636,0.00012629677,0.00017350445,0.000034905806,0.000048390342,0.000011747981,0.00003738717,0.000011320185],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99804014,0.00020209976,0.00038571638,0.0005345859,0.00049672334,0.0003407298],"domain_scores_gemma":[0.9992634,0.00015154287,0.00017955135,0.00028790566,0.000041821142,0.00007579717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026815207,0.00021000867,0.0001807407,0.00026685235,0.00007146889,0.000058221263,0.00023198391,0.00008578088,0.0002912293],"category_scores_gemma":[0.000118133576,0.00019329533,0.00008770885,0.0006103838,0.000068778354,0.00039045105,0.00009147785,0.00012858913,0.000044377906],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017810309,0.0017935503,0.36125997,0.0005345735,0.038636025,0.00028236266,0.0099757435,0.0011563163,0.40402305,0.005001381,0.053790797,0.1217652],"study_design_scores_gemma":[0.0031233039,0.0002357785,0.63634586,0.0002485377,0.0032343392,0.0000040749856,0.0002687723,0.0044463803,0.3493452,0.00038092953,0.0018074847,0.0005593453],"about_ca_topic_score_codex":0.000060908376,"about_ca_topic_score_gemma":0.00031392873,"teacher_disagreement_score":0.2750859,"about_ca_system_score_codex":0.000019729236,"about_ca_system_score_gemma":0.00006820337,"threshold_uncertainty_score":0.7882355},"labels":[],"label_agreement":null},{"id":"W4406235634","doi":"10.1016/j.endend.2014.01.037","title":"10.1016/j.endend.2014.01.037","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Population; Psychology; Clinical psychology; Medicine; Psychiatry; Developmental psychology; Environmental health","score_opus":0.011096734090490489,"score_gpt":0.19784482282704363,"score_spread":0.18674808873655313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406235634","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0024939731,0.000026000776,8.2547285e-7,0.0004859548,0.0000032711446,0.00016707937,0.000016755599,0.00025457525,0.9965516],"genre_scores_gemma":[0.0021649124,5.297262e-7,0.00003577602,0.0004438235,0.00008454305,0.000013766682,0.0000025563397,0.000028091303,0.997226],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988274,0.00006063756,0.00014304057,0.0003802442,0.00023604844,0.0003526258],"domain_scores_gemma":[0.9993828,0.00009276268,0.00002304577,0.00033136754,0.000009856844,0.00016020163],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00006857763,0.00014716652,0.00013089603,0.00007423644,0.00010422986,0.000060676113,0.00036533718,0.00005485305,0.99790794],"category_scores_gemma":[0.00011002326,0.00013980479,0.000065763,0.00026054026,0.00006751469,0.00012509743,0.000047324174,0.000111450136,0.9978384],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062429484,0.00007034309,4.5314028e-8,0.0000036066353,0.0000020131515,0.000011971957,0.000022990655,0.000029476209,0.006633255,0.000007761224,0.5241912,0.46896487],"study_design_scores_gemma":[0.00027830485,0.00009437742,0.000034142628,0.0000060760244,0.00000274853,0.000009519738,0.0000011804603,0.000082643164,0.010906132,0.000039642204,0.9883576,0.00018763373],"about_ca_topic_score_codex":0.0000073751394,"about_ca_topic_score_gemma":2.0675085e-7,"teacher_disagreement_score":0.46877724,"about_ca_system_score_codex":0.000018836705,"about_ca_system_score_gemma":0.000024155312,"threshold_uncertainty_score":0.5701074},"labels":[],"label_agreement":null},{"id":"W4406250329","doi":"10.2174/0118715303325541241024060229","title":"Beyond the Surface: Tracing the Evolution of Inflammatory Mechanism in Depression through Bibliometric Analysis","year":2025,"lang":"en","type":"article","venue":"Endocrine Metabolic & Immune Disorders - Drug Targets","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Bibliometrics; Depression (economics); Mechanism (biology); Web of science; Political science; China; Medicine; Library science; Geography; MEDLINE; Computer science","score_opus":0.0073174155934371205,"score_gpt":0.25871957601265083,"score_spread":0.2514021604192137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406250329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92986786,0.05820936,0.0045213085,0.001491723,0.0006269531,0.0008544603,0.000017420865,0.00009954085,0.0043113614],"genre_scores_gemma":[0.9946188,0.0042378134,0.00012449402,0.00031063854,0.000020520594,0.000078221165,0.000008326685,0.000029337392,0.0005718476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99623615,0.0008170688,0.0009067598,0.0006617449,0.0006774527,0.0007008037],"domain_scores_gemma":[0.9976342,0.0008961686,0.00038774344,0.0009705092,0.000071345734,0.000040083105],"candidate_categories":["metaepi_narrow","bibliometrics"],"consensus_categories":["bibliometrics"],"category_scores_codex":[0.000846842,0.00038984476,0.0006769883,0.011403153,0.00049842853,0.00007879751,0.0012323309,0.00006706663,0.00011534757],"category_scores_gemma":[0.0010943688,0.00025077362,0.0005059724,0.09465362,0.00033979747,0.00047342785,0.0004150201,0.0005357374,0.000014022029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045800288,0.0019902573,0.08780394,0.00025919828,0.0012479647,0.000025432502,0.011943876,0.04298739,0.6021474,0.19198954,0.0015342929,0.05761273],"study_design_scores_gemma":[0.0026832344,0.000022997387,0.42538273,0.000046592482,0.00043333543,0.0000035345865,0.005229104,0.0046592117,0.50584227,0.049437612,0.0057304967,0.0005288711],"about_ca_topic_score_codex":0.001977652,"about_ca_topic_score_gemma":0.0006182242,"teacher_disagreement_score":0.3375788,"about_ca_system_score_codex":0.000063175394,"about_ca_system_score_gemma":0.00013497849,"threshold_uncertainty_score":0.99999446},"labels":[],"label_agreement":null},{"id":"W4406366181","doi":"10.21203/rs.3.rs-5759131/v1","title":"Differential associations between cytokine and complement proteins in the clinical high risk and first episode stages of psychosis: Blood based investigation across three international studies of psychosis: NEURAPRO, STEP and OPTiMiSE","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Regional Development Fund; Medical Research Council; National Health and Medical Research Council; Queen's University; Science Foundation Ireland; Beyond Blue; Queen's University Belfast","keywords":"Psychosis; Immunology; C4A; Complement (music); Complement system; Cytokine; Medicine; Cohort; C-reactive protein; Inflammation; Internal medicine; Immune system; Biology; Psychiatry; Gene; Genetics","score_opus":0.1930951312363114,"score_gpt":0.46539276092277926,"score_spread":0.27229762968646787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406366181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876741,0.0005252872,0.00022885784,0.00461409,0.00010457356,0.0022445614,0.0045759566,0.000017102337,0.000015449228],"genre_scores_gemma":[0.99416196,0.0045623383,0.0005844929,0.000049593244,0.00006866013,0.0004703825,0.000081204984,0.000012117642,0.000009254891],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99576527,0.0013547231,0.0008206685,0.00074507325,0.0009904471,0.00032381006],"domain_scores_gemma":[0.9952844,0.0034622303,0.0004488604,0.00042158054,0.00030058675,0.00008237864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002080842,0.00022972292,0.0005375486,0.00030595055,0.0003212025,0.00014015891,0.0005389892,0.00018194367,0.000008919961],"category_scores_gemma":[0.0029482038,0.00017856406,0.00008808194,0.0003776099,0.0011194268,0.00008496729,0.0009006452,0.0009890214,1.6658402e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010997662,0.0004930318,0.9913734,0.00095964334,0.00016301633,0.0000016937439,0.0015509676,0.000053784122,0.0002601685,0.00034097966,0.00030008052,0.0043932195],"study_design_scores_gemma":[0.002568838,0.00040429004,0.98875445,0.0009784262,0.000051675837,1.9604491e-7,0.0006675271,0.0007502507,0.002319459,0.0033024054,0.000056571862,0.00014592787],"about_ca_topic_score_codex":0.0011356217,"about_ca_topic_score_gemma":0.0043519638,"teacher_disagreement_score":0.006487834,"about_ca_system_score_codex":0.000037145077,"about_ca_system_score_gemma":0.000070420516,"threshold_uncertainty_score":0.7281631},"labels":[],"label_agreement":null},{"id":"W4406580352","doi":"10.1016/s1541-9800(07)70337-x","title":"10.1016/s1541-9800(07)70337-x","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Tumor necrosis factor alpha; Depression (economics); Psychology; Psychotherapist; Medicine; Immunology","score_opus":0.011057394915861359,"score_gpt":0.19388636543012872,"score_spread":0.18282897051426736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406580352","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004368177,0.000024792846,6.979978e-7,0.0005652529,0.0000028361608,0.0001862107,0.000015846368,0.00024592862,0.9945903],"genre_scores_gemma":[0.0022791412,5.087473e-7,0.000038370516,0.00055893994,0.00008243443,0.000014842772,0.00000253889,0.000028284576,0.9969949],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987943,0.00005763667,0.00015240794,0.0003893489,0.00023652823,0.000369787],"domain_scores_gemma":[0.99936664,0.00009393356,0.000023581404,0.00033459347,0.000013038627,0.00016819566],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000068308014,0.00015550808,0.00013977234,0.0000724894,0.00011841868,0.00006445618,0.00037672473,0.00005699575,0.9983168],"category_scores_gemma":[0.00015040996,0.00014830419,0.000068580404,0.00033096777,0.00007386034,0.00012883537,0.000047992013,0.0001149192,0.9985764],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000077122044,0.000096029056,5.2332144e-8,0.0000049574014,0.0000024266935,0.000015729884,0.000033655277,0.000041832158,0.0066999677,0.000007795991,0.4675922,0.52542824],"study_design_scores_gemma":[0.0003008395,0.00010493211,0.00003301121,0.000008064728,0.0000029077646,0.000011420914,0.0000012030449,0.00010965314,0.010707543,0.000043898377,0.98847616,0.00020038248],"about_ca_topic_score_codex":0.000007960876,"about_ca_topic_score_gemma":1.4196199e-7,"teacher_disagreement_score":0.52522784,"about_ca_system_score_codex":0.000019953535,"about_ca_system_score_gemma":0.000025821126,"threshold_uncertainty_score":0.6047669},"labels":[],"label_agreement":null},{"id":"W4406596983","doi":"10.9758/cpn.24.1236","title":"Association of Cognitive Impairment and Peripheral Inflammation in Methamphetamine-dependent Patients: A Cross-sectional Study on Neuroinflammatory Markers TNF-α and IL-6","year":2025,"lang":"en","type":"article","venue":"Clinical Psychopharmacology and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Chulabhorn Graduate Institute, Chulabhorn Royal Academy","keywords":"Peripheral; Association (psychology); Cross-sectional study; Inflammation; Medicine; Neuroinflammation; Cognitive impairment; Tumor necrosis factor alpha; Methamphetamine; Cognition; Internal medicine; Immunology; Psychology; Psychiatry; Pathology; Psychotherapist","score_opus":0.03214498222785772,"score_gpt":0.3899250243986756,"score_spread":0.3577800421708179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406596983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972422,0.000017629516,0.00001565651,0.00033360772,0.0012587869,0.0008430613,0.000019069723,0.000023679355,0.00024630467],"genre_scores_gemma":[0.9972801,0.00021956873,0.0000035702103,0.0022095782,0.000025371683,0.00004346275,6.6212976e-7,0.0000065917293,0.00021104654],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99716085,0.0008394201,0.000671293,0.00080474425,0.00027913286,0.00024453716],"domain_scores_gemma":[0.9971768,0.0022959737,0.00027666302,0.00009539309,0.000058197566,0.000096917895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011595847,0.00016653126,0.0002552567,0.00019568404,0.0001798968,0.000055254102,0.00013925976,0.00012289347,0.000014588328],"category_scores_gemma":[0.0027276042,0.00015786094,0.000042673717,0.0003133718,0.00066470786,0.00022975857,0.00013025789,0.00038846314,0.0000012712821],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015658379,0.0009032271,0.98102874,0.000018816085,0.0000067846436,0.0000091018155,0.0001367504,0.000015755892,0.013976792,0.00004568192,0.00005119962,0.0022413288],"study_design_scores_gemma":[0.0080379825,0.0013322294,0.9880093,0.000017269262,0.000013610985,0.0000018306006,0.00006357678,0.00044458354,0.0017415638,0.00017406826,0.00004994767,0.000114050395],"about_ca_topic_score_codex":0.000003970102,"about_ca_topic_score_gemma":0.000009150136,"teacher_disagreement_score":0.012235228,"about_ca_system_score_codex":0.000035203968,"about_ca_system_score_gemma":0.000047451013,"threshold_uncertainty_score":0.6437382},"labels":[],"label_agreement":null},{"id":"W4406622463","doi":"10.1186/s13075-024-03466-8","title":"Do individuals with inflammatory arthritis receive minimally adequate treatment for incident depression and anxiety: A population-based study","year":2025,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia Hospital; British Columbia Centre on Substance Use; Centre for Advancing Health Outcomes; Simon Fraser University; Research Canada; Arthritis Research Centre of Canada; McGill University; University of British Columbia","funders":"Arthritis Society","keywords":"Pharmacotherapy; Anxiety; Medicine; Depression (economics); Internal medicine; Population; Medical prescription; Antidepressant; Odds ratio; Anxiety disorder; Psychiatry; Physical therapy; Pharmacology","score_opus":0.04649076880221141,"score_gpt":0.3512959503818771,"score_spread":0.3048051815796657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406622463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908994,0.0042475336,0.000060305298,0.000655736,0.000061071965,0.0037627404,0.00005496316,0.00008614876,0.0001721115],"genre_scores_gemma":[0.99058294,0.0065485123,0.0002422638,0.00034061284,0.00003653477,0.0020009694,0.00001448182,0.000034780307,0.00019887532],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9968234,0.00070250296,0.00032943726,0.0008447793,0.0007039545,0.00059598364],"domain_scores_gemma":[0.99813753,0.0010303893,0.00008288121,0.00044607272,0.00014626782,0.0001568485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007184841,0.00024911997,0.00030042275,0.0004266095,0.0006987913,0.00032629797,0.00026172106,0.00008699981,0.00006715312],"category_scores_gemma":[0.00031507207,0.00020051251,0.0000687325,0.0005659689,0.00019430585,0.00024469694,0.000068636284,0.00020046749,0.000007937746],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010407964,0.00074097863,0.3139706,0.00001079018,0.00004160845,0.000041741594,0.0020720002,0.000017376276,0.0092091365,0.0002847827,0.00019468546,0.6723755],"study_design_scores_gemma":[0.035567623,0.008756038,0.84192646,0.0007897274,0.0000088697,0.00001412979,0.004290632,0.00019834151,0.08438503,0.0039355,0.019454617,0.00067304476],"about_ca_topic_score_codex":0.00018872866,"about_ca_topic_score_gemma":0.00092175,"teacher_disagreement_score":0.67170244,"about_ca_system_score_codex":0.00010552551,"about_ca_system_score_gemma":0.00026980616,"threshold_uncertainty_score":0.8176663},"labels":[],"label_agreement":null},{"id":"W4406664663","doi":"10.1159/000543691","title":"The Perinatal Microbiota-Gut-Brain Axis: Implications for Postpartum Depression","year":2025,"lang":"en","type":"review","venue":"NeuroImmunoModulation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"AstraZeneca","keywords":"Gut–brain axis; Gut flora; Mood disorders; Mood; Postpartum depression; Postpartum period; Depression (economics); Vulnerability (computing); Oxytocin; GABAergic; Biology; Pregnancy; Psychology; Medicine; Physiology; Neuroscience; Immunology; Anxiety; Psychiatry; Genetics","score_opus":0.0473552676274806,"score_gpt":0.3420961967301063,"score_spread":0.29474092910262567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406664663","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006213456,0.9921172,0.000600736,0.0014363071,0.001086066,0.003108097,0.00038303007,0.00019884681,0.0010075287],"genre_scores_gemma":[0.0011040048,0.99396646,0.00004778622,0.0004165614,0.000102825055,0.00076375494,0.00024470568,0.00007396922,0.0032799297],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976492,0.00032872986,0.0006226921,0.00083871523,0.00013741721,0.00042325543],"domain_scores_gemma":[0.9956719,0.0028111523,0.00041377047,0.0009977338,0.000058554153,0.00004688933],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017847755,0.00042973313,0.00057045196,0.00019279166,0.0010783017,0.00029857235,0.0008794013,0.00019784934,0.00000796726],"category_scores_gemma":[0.0016833976,0.0003118015,0.0005491462,0.0005765219,0.00013092543,0.00017587969,0.00021295823,0.00034757407,0.000032956075],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021315675,0.00004157852,0.000001803834,0.0021263694,0.000011964355,8.131844e-7,0.000011780894,0.0000045371276,0.0043386454,0.004068138,0.004030658,0.9853424],"study_design_scores_gemma":[0.00023356137,0.000043761593,0.00061845913,0.0012542133,0.000053255626,0.000040942043,0.000002862246,0.00004512378,0.00014899568,0.0003026017,0.9969728,0.00028339695],"about_ca_topic_score_codex":0.0000024787967,"about_ca_topic_score_gemma":0.0000015918721,"teacher_disagreement_score":0.99294215,"about_ca_system_score_codex":0.00008816729,"about_ca_system_score_gemma":0.0002574531,"threshold_uncertainty_score":0.9999334},"labels":[],"label_agreement":null},{"id":"W4406682566","doi":"10.1016/j.jad.2025.01.101","title":"Simple dysmood disorder, a mild subtype of major depression, is not an inflammatory condition: Depletion of the compensatory immunoregulatory system","year":2025,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Faculty of Medicine, Chulalongkorn University; Chulalongkorn University; Faculty of Medicine, University of British Columbia","keywords":"Depression (economics); Inflammation; Simple (philosophy); Medicine; Psychiatry; Psychology; Immunology; Internal medicine","score_opus":0.007718953172748168,"score_gpt":0.2527826209232686,"score_spread":0.2450636677505204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406682566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965187,0.00073895126,0.00060584577,0.00017928774,0.00058546045,0.0005159233,0.000049553215,0.000025868363,0.0007804368],"genre_scores_gemma":[0.99948144,0.00005797571,0.000021112759,0.00034225566,0.000028139866,0.000011317671,0.0000020394982,0.000025602149,0.000030107034],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99743694,0.00065062084,0.0007722045,0.0002988851,0.0005890764,0.00025228816],"domain_scores_gemma":[0.99751186,0.00047194585,0.0011508059,0.0004961674,0.00029494922,0.000074272415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004222183,0.00025083922,0.00049448776,0.0003386037,0.00025393584,0.000023904988,0.0006624095,0.00014619465,0.000046799865],"category_scores_gemma":[0.0004457305,0.00018850494,0.00037325802,0.00067209813,0.00055156834,0.00038133663,0.00012069208,0.00035768707,0.0000020735758],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016976099,0.0014696881,0.31281033,0.0012238404,0.0003294628,0.000008403114,0.002418663,0.0010924612,0.65399456,0.012438987,0.0029184918,0.009597472],"study_design_scores_gemma":[0.0038317062,0.000322766,0.6671977,0.00044480458,0.00008134332,0.000016266215,0.0033893692,0.0002710944,0.32162485,0.0017275176,0.00086830097,0.00022428659],"about_ca_topic_score_codex":0.00007982859,"about_ca_topic_score_gemma":0.0001969456,"teacher_disagreement_score":0.35438737,"about_ca_system_score_codex":0.000104946615,"about_ca_system_score_gemma":0.0003073609,"threshold_uncertainty_score":0.76870084},"labels":[],"label_agreement":null},{"id":"W4406848454","doi":"10.1192/j.eurpsy.2025.7","title":"Associations between IL-6 and trajectories of depressive symptoms across the life course: Evidence from ALSPAC and UK Biobank cohorts","year":2025,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Medical Research Council; National Institutes of Health; Department of Health and Social Care; University of Bristol; National Institute for Health and Care Research; UK Research and Innovation; Wellcome Trust","keywords":"Biobank; Life course approach; Longitudinal study; Depressive symptoms; Gerontology; Psychology; Course (navigation); Medicine; Clinical psychology; Demography; Developmental psychology; Psychiatry; Anxiety; Biology; Bioinformatics; Sociology; Engineering; Pathology","score_opus":0.01970060563537522,"score_gpt":0.29760335246542297,"score_spread":0.27790274683004773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406848454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861655,0.007822154,0.000090626905,0.0029685053,0.0006940737,0.00022403068,0.0006730625,0.000058424586,0.0013036118],"genre_scores_gemma":[0.9982285,0.00025410057,0.00006171876,0.0011078693,0.00016114741,0.0000033142178,0.000006955414,0.000017479955,0.00015890453],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984721,0.00038075697,0.0002935819,0.00042241273,0.00020139538,0.00022976263],"domain_scores_gemma":[0.9984455,0.0008909836,0.00020782773,0.00034176867,0.000033708155,0.00008022779],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027055095,0.00016343017,0.00022940454,0.00003319044,0.00038726698,0.00012639206,0.00033248006,0.000047076566,0.00001369219],"category_scores_gemma":[0.00084832154,0.00012530427,0.000054043074,0.00030146466,0.00045562154,0.00013294346,0.00018030868,0.00019124488,0.000006780769],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018643805,0.00004362146,0.984158,0.00001890172,0.00007985832,0.0000019584363,0.0024140137,0.000003480689,0.0034182945,0.0011094077,0.0067552915,0.001978553],"study_design_scores_gemma":[0.0004061472,0.00003612804,0.99516034,0.00019636987,0.0000756002,7.38592e-7,0.0005425343,0.0000066117027,0.0020295111,0.00097521476,0.00043905145,0.00013177331],"about_ca_topic_score_codex":0.00007260637,"about_ca_topic_score_gemma":0.00007858203,"teacher_disagreement_score":0.012062999,"about_ca_system_score_codex":0.000006377343,"about_ca_system_score_gemma":0.00008558017,"threshold_uncertainty_score":0.510976},"labels":[],"label_agreement":null},{"id":"W4406869701","doi":"10.1016/j.euroneuro.2025.01.001","title":"A specific GPR56/ADGRG1 splicing isoform is associated with antidepressant response in major depressive disorder","year":2025,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"Agence Nationale de la Recherche","keywords":"Antidepressant; RNA splicing; Gene isoform; Alternative splicing; Biology; Psychology; Neuroscience; Internal medicine; Medicine; Genetics; Gene; Hippocampus","score_opus":0.016999843013654533,"score_gpt":0.2845278830022095,"score_spread":0.26752803998855496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406869701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9681708,0.00027058923,0.00013826859,0.0019967372,0.0008809539,0.0007637016,0.000027782104,0.00043006445,0.02732108],"genre_scores_gemma":[0.98269045,0.00028359308,0.00002778952,0.014516293,0.0000615376,0.000037622813,0.0000031792495,0.00014995353,0.0022295844],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9947911,0.0020631377,0.00060435524,0.0013207553,0.00031052422,0.000910108],"domain_scores_gemma":[0.9978808,0.0010442913,0.00026513165,0.000597956,0.000060655722,0.00015116767],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005402342,0.00047092437,0.00045546924,0.000659308,0.00026277747,0.000107019936,0.0009156975,0.0000885181,0.00032569794],"category_scores_gemma":[0.00057168934,0.0004247273,0.00011925231,0.0017170083,0.0004149394,0.000230432,0.0002961363,0.00079733756,0.00021560397],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0074281883,0.0007475761,0.006996817,0.000022959055,0.00004088669,0.0029573776,0.0008005477,0.00022754075,0.9636954,0.0001785227,0.013792929,0.0031112235],"study_design_scores_gemma":[0.019955538,0.00070661044,0.8682314,0.0002239914,0.000049622973,0.00010066981,0.00015257229,0.00058219454,0.06252435,0.00018580264,0.046379752,0.00090747484],"about_ca_topic_score_codex":0.000010678122,"about_ca_topic_score_gemma":0.000012182181,"teacher_disagreement_score":0.9011711,"about_ca_system_score_codex":0.00007525205,"about_ca_system_score_gemma":0.00008040125,"threshold_uncertainty_score":0.9998205},"labels":[],"label_agreement":null},{"id":"W4406877311","doi":"10.1016/j.jbc.2025.108230","title":"Exogenous L-fucose attenuates depression induced by chronic unpredictable stress: Implicating core fucosylation has an antidepressant potential","year":2025,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Glycomics Network; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Fucosylation; Neuroinflammation; Fucose; Chemistry; Cell biology; Biochemistry; Inflammation; Biology; Immunology","score_opus":0.043946074508464474,"score_gpt":0.2875553071214236,"score_spread":0.2436092326129591,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406877311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971833,0.0012824226,0.0005333718,0.00026116802,0.0001266757,0.000109716246,0.000046441754,0.000053408763,0.00040349847],"genre_scores_gemma":[0.99915826,0.0002773428,0.00009522905,0.00018178995,0.00020460076,0.0000048424085,0.0000243269,0.000010200097,0.000043399123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983932,0.000084392974,0.0005375784,0.00039076584,0.00025114545,0.0003429521],"domain_scores_gemma":[0.99887973,0.00016475077,0.00046708246,0.00024973415,0.00008953574,0.00014915863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002043942,0.00020151465,0.00029727202,0.00004205217,0.00028384724,0.000107035536,0.00055818446,0.00026910927,0.00012770461],"category_scores_gemma":[0.00060021,0.00014344597,0.00013154869,0.00023584376,0.0001654726,0.0001962869,0.00014271888,0.00047630686,0.0000028089669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011099834,0.00026299217,0.004100836,0.00003837104,0.0000115316525,0.000023507111,0.000022155198,0.0000994877,0.9871571,0.000004608742,0.00050162553,0.0076667652],"study_design_scores_gemma":[0.0008500236,0.00018054394,0.005645578,0.00013760135,0.000014210358,0.000073275514,0.000114544564,0.0007460689,0.99121606,0.0005585849,0.000306859,0.00015662202],"about_ca_topic_score_codex":0.000008285844,"about_ca_topic_score_gemma":7.1210206e-7,"teacher_disagreement_score":0.0075101433,"about_ca_system_score_codex":0.00008452217,"about_ca_system_score_gemma":0.00013525444,"threshold_uncertainty_score":0.5849557},"labels":[],"label_agreement":null},{"id":"W4407048389","doi":"10.1007/978-3-031-67821-9_7","title":"Wohlbefinden","year":2024,"lang":"de","type":"book-chapter","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Association of Nurses in Oncology; Vancouver General Hospital","funders":"","keywords":"Psychology","score_opus":0.03260272456175091,"score_gpt":0.2540016066711438,"score_spread":0.2213988821093929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407048389","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000112415895,0.00282609,0.00003708718,0.0023196733,0.003490471,0.00037703317,0.000099245764,0.000389725,0.9903483],"genre_scores_gemma":[0.019770578,0.0015359984,0.000057460606,0.0037557269,0.00058851275,0.000007838963,0.0000137303105,0.00015733072,0.9741128],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.997125,0.000017517343,0.00044535843,0.0012854427,0.0005981078,0.0005285489],"domain_scores_gemma":[0.99875647,0.00021940708,0.00009992149,0.00067922333,0.00002748007,0.00021751973],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001070153,0.00063200656,0.00043253775,0.00032316768,0.0001371298,0.0003215972,0.00066897995,0.0005395767,0.03927807],"category_scores_gemma":[0.00007743941,0.0005515747,0.0004292736,0.000109354,0.00042105676,0.00009188267,0.0003799249,0.000914556,0.18824889],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015356085,0.000024177398,0.000001228914,0.0001190258,0.000039525752,0.00034460163,0.000092890514,0.0000014287015,0.002635714,0.9678195,0.023529131,0.005377436],"study_design_scores_gemma":[0.00020364538,0.00009230018,0.000008143954,0.00021599702,0.00005273582,0.00002640043,0.000025981804,0.000085846325,0.003916322,0.09136525,0.9033609,0.0006464479],"about_ca_topic_score_codex":0.000017401739,"about_ca_topic_score_gemma":0.000027633741,"teacher_disagreement_score":0.8798318,"about_ca_system_score_codex":0.00005703479,"about_ca_system_score_gemma":0.000101085134,"threshold_uncertainty_score":0.9996936},"labels":[],"label_agreement":null},{"id":"W4407056154","doi":"10.1016/j.jad.2025.01.150","title":"Peripheral protein inflammatory biomarkers in bipolar disorder and major depressive disorder: A systematic review and meta-analysis","year":2025,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Bipolar disorder; Meta-analysis; Major depressive disorder; Biomarker; Peripheral; Medicine; Inflammation; Psychology; Psychiatry; Bioinformatics; Clinical psychology; Internal medicine; Biology; Mood; Genetics","score_opus":0.018558654360427054,"score_gpt":0.2987678180948717,"score_spread":0.28020916373444466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407056154","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016477247,0.9924309,0.0001946119,0.00027414004,0.000057689842,0.0066700988,0.00009943878,0.00002676211,0.00008156709],"genre_scores_gemma":[0.00045770884,0.9980629,0.00005039791,0.0002752887,0.000011138899,0.0008859455,0.0000064229944,0.00007437928,0.00017581748],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99229914,0.0033598067,0.0021267205,0.0009977013,0.0006451033,0.00057151425],"domain_scores_gemma":[0.99467343,0.0018041799,0.0025636372,0.00059915474,0.00013262499,0.000226983],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012292829,0.0011114102,0.009044136,0.0021278826,0.00022276319,0.00017870842,0.0007447469,0.00037053463,0.000083741004],"category_scores_gemma":[0.0040245396,0.000754645,0.0031063608,0.003302893,0.0004575149,0.00051679555,0.00028036162,0.001018097,0.0000028352054],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034022272,0.00030973647,0.00011181609,0.89604354,0.06877096,0.00006448861,0.00019813991,0.000007925403,0.0000064723063,0.0001534969,0.000053778673,0.034245636],"study_design_scores_gemma":[0.0023781422,0.00039507909,0.000099706056,0.09537627,0.8723323,0.00016216909,0.00047419738,0.000026195334,0.000007564364,0.00045899407,0.02646304,0.0018263934],"about_ca_topic_score_codex":0.00009874209,"about_ca_topic_score_gemma":0.0010131125,"teacher_disagreement_score":0.8035613,"about_ca_system_score_codex":0.0001511529,"about_ca_system_score_gemma":0.00038486088,"threshold_uncertainty_score":0.99949044},"labels":[],"label_agreement":null},{"id":"W4407179304","doi":"10.1007/978-3-031-80490-8_2","title":"SSRIs","year":2024,"lang":"en","type":"book-chapter","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Psychology","score_opus":0.03464755713046368,"score_gpt":0.2517430836535256,"score_spread":0.2170955265230619,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407179304","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000007897858,0.00028284866,0.000012280271,0.0005703007,0.0005449799,0.000101189486,0.000021581867,0.00032434592,0.99813455],"genre_scores_gemma":[0.0019637628,0.0002056453,0.000021011241,0.0021256711,0.00012663631,0.0000023395294,0.0000020355862,0.000052872187,0.9955],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991508,0.0000023303471,0.00011252343,0.00041077577,0.00018466073,0.00013887836],"domain_scores_gemma":[0.99963325,0.0000611539,0.000023832812,0.00022691154,0.0000054533534,0.000049411043],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000018635292,0.00017839292,0.000127785,0.000097809185,0.000029884533,0.000057010227,0.00019421158,0.00015074544,0.0095070535],"category_scores_gemma":[0.000022168364,0.00014237654,0.00012801755,0.000020652382,0.00008557002,0.000029119656,0.00008941995,0.00025508055,0.02011245],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000014956091,0.0000025298789,2.6521352e-8,0.000020006271,0.0000029107362,0.00005390773,0.000013141587,1.08052745e-7,0.0013990495,0.93680793,0.05808507,0.0036138243],"study_design_scores_gemma":[0.00003429176,0.000013170785,2.6944932e-7,0.000027103693,0.0000043738787,0.000008395008,0.000002060562,0.000006517668,0.004282619,0.2401074,0.7553662,0.00014757933],"about_ca_topic_score_codex":0.0000020706966,"about_ca_topic_score_gemma":0.000006371805,"teacher_disagreement_score":0.6972811,"about_ca_system_score_codex":0.000015532685,"about_ca_system_score_gemma":0.000024650257,"threshold_uncertainty_score":0.9913984},"labels":[],"label_agreement":null},{"id":"W4407199633","doi":"10.5664/jcsm.11588","title":"Shared underlying dynamics between sleep disorder and psychiatric disorder: proinflammatory state?","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Sleep Medicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child, Adolescent and Family Mental Health","funders":"","keywords":"Medicine; Psychiatry; Sleep (system call); Clinical psychology","score_opus":0.0509129170964777,"score_gpt":0.381194524349467,"score_spread":0.3302816072529893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407199633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95515096,0.0021565482,0.016901119,0.021751178,0.0017406945,0.00039196672,0.000018291074,0.00004880644,0.001840424],"genre_scores_gemma":[0.99538654,0.00130568,0.0005290795,0.0018533666,0.000453566,0.000003738593,0.000003510669,0.000029123767,0.00043537447],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99582416,0.0003936432,0.0023015025,0.00044263544,0.00064914953,0.0003888933],"domain_scores_gemma":[0.9953691,0.0027993622,0.0010281017,0.00031154152,0.00013634018,0.00035555998],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017402631,0.00028068174,0.0009990173,0.0004094913,0.00021167091,0.00005042416,0.0005598126,0.00019025948,0.00008265149],"category_scores_gemma":[0.0059508677,0.00019955267,0.00024090431,0.0007781948,0.0005836493,0.0003026452,0.00013610571,0.0010693661,0.000008683418],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042534742,0.00037612804,0.5277656,0.00018356269,0.00012668384,0.00005789178,0.00016459092,0.000086829,0.00016582989,0.0018195566,0.0021992915,0.4666287],"study_design_scores_gemma":[0.015067257,0.002020948,0.924386,0.0005067578,0.00030856938,0.000049356742,0.00089509913,0.0077463957,0.000048339523,0.032633185,0.015844291,0.0004937509],"about_ca_topic_score_codex":0.00001982959,"about_ca_topic_score_gemma":0.00012034126,"teacher_disagreement_score":0.46613494,"about_ca_system_score_codex":0.00004589603,"about_ca_system_score_gemma":0.00015185997,"threshold_uncertainty_score":0.8137522},"labels":[],"label_agreement":null},{"id":"W4407246440","doi":"10.1016/j.biopsych.2025.01.028","title":"Transcriptional and Neurochemical Signatures of Cerebral Blood Flow Alterations in Individuals With Schizophrenia or at Clinical High Risk for Psychosis","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Montreal Neurological Institute and Hospital","funders":"NIHR Maudsley Biomedical Research Centre; King's College London; Department of Health and Social Care; Mental Health Research UK; Wellcome Trust; National Institute for Health and Care Research; Medical Research Council; Royal Society; Schizophrenia Research Fund","keywords":"Neurochemical; Psychosis; Schizophrenia (object-oriented programming); Cerebral blood flow; Neuroscience; Medicine; Psychiatry; Psychology; Internal medicine","score_opus":0.03234403373467675,"score_gpt":0.3029773682771533,"score_spread":0.27063333454247657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407246440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960486,0.0002899719,0.0003590658,0.0019138124,0.00041546163,0.0004703901,0.00036997625,0.00004155293,0.000091144604],"genre_scores_gemma":[0.98400223,0.00015186906,0.0137145,0.0018782902,0.00009495553,0.00006980882,0.000023868826,0.0000080276395,0.000056461646],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99837315,0.00020569873,0.0004542476,0.0006123038,0.000119415796,0.0002351545],"domain_scores_gemma":[0.9988644,0.0007669012,0.00010789139,0.0001661861,0.000019466313,0.00007511674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016887451,0.00017762523,0.0002981503,0.00010095912,0.00013051406,0.000022348207,0.00022592528,0.00025537802,0.000074423675],"category_scores_gemma":[0.00046988646,0.00011018672,0.000112679365,0.0003213954,0.00039462652,0.00005100812,0.00004478654,0.0002990739,0.0000014192663],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0072393836,0.0025115863,0.89884967,0.00009080335,0.00008193384,0.0000019632262,0.00006166908,0.000052048395,0.04218593,0.041032296,0.0048583746,0.0030343402],"study_design_scores_gemma":[0.0093324315,0.0014470362,0.96348804,0.00007591549,0.000052696283,0.0000066668686,0.000031483152,0.00020510775,0.0049625104,0.019168144,0.00096169824,0.00026827017],"about_ca_topic_score_codex":0.0000055050346,"about_ca_topic_score_gemma":0.00010261874,"teacher_disagreement_score":0.06463837,"about_ca_system_score_codex":0.0000057212296,"about_ca_system_score_gemma":0.00006443102,"threshold_uncertainty_score":0.4493284},"labels":[],"label_agreement":null},{"id":"W4407342406","doi":"10.1152/ajpcell.00869.2024","title":"Microbiota protect against frailty and loss of skeletal muscle, and maintain inflammatory tone during aging in mice","year":2025,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University; Population Health Research Institute","funders":"Institute of Aging; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Skeletal muscle; Tone (literature); Inflammation; Muscle tone; Sarcopenia; Medicine; Neuroscience; Biology; Immunology; Endocrinology; Art","score_opus":0.005726901546857559,"score_gpt":0.2402020891816535,"score_spread":0.23447518763479594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407342406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990307,0.00025994194,0.000014125089,0.00027867398,0.00010077902,0.00019368471,0.0000072397183,0.000012223612,0.00010261358],"genre_scores_gemma":[0.9986724,0.00041889152,0.000235612,0.00058028474,0.000050061157,0.0000054810566,8.3819367e-7,0.000016236063,0.000020180492],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803835,0.0004750979,0.0005785626,0.00042481508,0.00008194543,0.0004012241],"domain_scores_gemma":[0.9986732,0.00036224863,0.00064359774,0.00019317225,0.000050152736,0.00007764252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018641962,0.0002400552,0.0006893124,0.00037129334,0.00008825883,0.000009142781,0.00031976518,0.00008309047,0.000008714584],"category_scores_gemma":[0.0001538731,0.00021544789,0.000106383086,0.00042940228,0.0017929657,0.00012906453,0.00023387704,0.00050782337,0.0000015388109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002016613,0.00013297891,0.0002695065,0.00016514394,0.000019622543,0.000015690155,0.00024827142,0.00017098003,0.9960486,0.00015753337,0.00001526987,0.0025546863],"study_design_scores_gemma":[0.0021973585,0.0004477222,0.35491458,0.00015913909,0.000012090437,0.000037461967,0.0009669023,0.00005945844,0.63881993,0.001969262,0.00017069938,0.00024539],"about_ca_topic_score_codex":0.000036628644,"about_ca_topic_score_gemma":0.000008904852,"teacher_disagreement_score":0.3572287,"about_ca_system_score_codex":0.00004106424,"about_ca_system_score_gemma":0.00009773428,"threshold_uncertainty_score":0.878571},"labels":[],"label_agreement":null},{"id":"W4407417924","doi":"10.1093/ijnp/pyae059.129","title":"ANTI-COMPULSIVE ACTION OF ESCITALOPRAM IN DEER MICE PARALLELS DECREASED PLASMA LIPOPOLYSACCHARIDE AND INCREASED FRONTAL-CORTICAL AND STRIATAL TRYPTOPHAN, BUT NOT SEROTONIN CONCENTRATIONS","year":2025,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences North","funders":"","keywords":"Escitalopram; Serotonin; Tryptophan; Lipopolysaccharide; Psychology; Quinolinic acid; Action (physics); Internal medicine; Endocrinology; Citalopram; Neuroscience; Pharmacology; Chemistry; Medicine; Antidepressant; Biochemistry; Receptor; Hippocampus; Amino acid","score_opus":0.024282222076405218,"score_gpt":0.3214582438396153,"score_spread":0.29717602176321006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407417924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99424314,0.000065326945,0.00017988685,0.003936787,0.0011657847,0.00026790242,0.00003333858,0.00000948491,0.00009831633],"genre_scores_gemma":[0.9966252,0.00042769208,0.00010383359,0.0027082604,0.00008190876,0.000007724682,0.00000150053,0.000009309262,0.000034599114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832594,0.00036632747,0.0005812915,0.0002404391,0.00030357862,0.00018244497],"domain_scores_gemma":[0.998114,0.0012127594,0.0003651094,0.00008218093,0.00013483196,0.000091123395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022434426,0.00014986226,0.00027114482,0.0002813056,0.00007753706,0.00005426956,0.0004487618,0.00006538418,0.00005592507],"category_scores_gemma":[0.000595413,0.00012111994,0.000070714625,0.00015816803,0.00034158534,0.0002437993,0.0000939724,0.00042733882,0.000002021529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002607105,0.00025723316,0.0025110857,0.000008444061,0.00006326231,0.000096085605,0.00013764747,0.00011562619,0.9910934,0.00092012744,0.00018739753,0.0020026015],"study_design_scores_gemma":[0.0072957235,0.00017065289,0.16122259,0.000046618927,0.00004833532,0.00037240595,0.00021076384,0.0030876233,0.82658374,0.0005907422,0.00025473553,0.00011609354],"about_ca_topic_score_codex":0.0000714139,"about_ca_topic_score_gemma":0.00003208711,"teacher_disagreement_score":0.16450967,"about_ca_system_score_codex":0.000043979697,"about_ca_system_score_gemma":0.00014465635,"threshold_uncertainty_score":0.4939128},"labels":[],"label_agreement":null},{"id":"W4407431362","doi":"10.1016/j.bpj.2024.11.707","title":"BPS2025 - Dual effects of mefenamic acid on the IKs molecular complex","year":2025,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Studies; University of British Columbia","funders":"","keywords":"Mefenamic acid; Dual (grammatical number); Chemistry; Computational biology; Biology; Philosophy; Chromatography","score_opus":0.01584516638810249,"score_gpt":0.2636971568244258,"score_spread":0.2478519904363233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407431362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99124235,0.000024977337,0.0008544836,0.0030717528,0.00034745858,0.00015605209,0.0000045318093,0.000023468465,0.004274912],"genre_scores_gemma":[0.99627966,0.000013737904,0.000037798345,0.0034545527,0.000067474866,0.000003844626,3.2680845e-7,0.000007950794,0.00013465762],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889696,0.00021432566,0.00017649829,0.00018080174,0.00031072175,0.00022070108],"domain_scores_gemma":[0.99915284,0.00047263264,0.00008628696,0.00020416264,0.000024833396,0.00005926853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007079703,0.00012770761,0.00017083655,0.000076845405,0.00016822224,0.000054446227,0.00034933476,0.00004125457,0.000038686285],"category_scores_gemma":[0.00036365518,0.000078897254,0.00018143746,0.00034369394,0.00022626304,0.000043418662,0.000075731965,0.00033040738,0.000045374167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039974093,0.00018069128,0.0000035804026,0.00001756315,0.000015035222,0.000046003384,0.000032471715,0.000009095458,0.9360626,0.060066577,0.0015202521,0.0020061976],"study_design_scores_gemma":[0.0004954656,0.00016159644,0.00250618,0.000063132386,0.000013931318,0.000010870525,0.000021077314,0.0003159691,0.99142575,0.004265606,0.00064059906,0.00007981858],"about_ca_topic_score_codex":0.0000016278676,"about_ca_topic_score_gemma":1.8963107e-7,"teacher_disagreement_score":0.05580097,"about_ca_system_score_codex":0.000019278152,"about_ca_system_score_gemma":0.000045122866,"threshold_uncertainty_score":0.32173365},"labels":[],"label_agreement":null},{"id":"W4407463984","doi":"10.1016/j.bbih.2025.100962","title":"Specific immune-inflammatory profiles and neurocognitive deficits predict illness trajectories in people with type 2 diabetes mellitus or psychiatric disorders","year":2025,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Regional Development Fund; Instituto de Salud Carlos III; Fundación Española para la Ciencia y la Tecnología; Ministerio de Ciencia e Innovación; Grand Challenges Canada; Foundation for Iranian Studies","keywords":"Neurocognitive; Type 2 Diabetes Mellitus; Immune system; Diabetes mellitus; Psychiatry; Medicine; Inflammation; Psychology; Clinical psychology; Immunology; Cognition; Endocrinology","score_opus":0.015786683283413972,"score_gpt":0.2749196229148949,"score_spread":0.25913293963148093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407463984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99170595,0.0036107474,0.000021960923,0.0012255771,0.0005337417,0.0022442106,0.0000713499,0.00021817638,0.00036826704],"genre_scores_gemma":[0.9951044,0.0032862944,0.0000992809,0.0008486967,0.000025139943,0.00031372203,0.000035862555,0.000058462345,0.00022819579],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9965871,0.00086307037,0.0006301112,0.00072708825,0.0003432634,0.0008493458],"domain_scores_gemma":[0.99802935,0.00096167193,0.00023435324,0.00054630596,0.000066119675,0.00016219063],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004713181,0.00044422073,0.0005705862,0.00057164667,0.00077837094,0.00012656678,0.00046155733,0.00014261264,0.000051958184],"category_scores_gemma":[0.00041956172,0.00037697534,0.0000707388,0.002267901,0.00047060207,0.00033211778,0.00015096592,0.0007208048,0.00000889833],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031722698,0.004399349,0.7085792,0.0021966116,0.00004503503,0.00006555541,0.01838333,0.000030088957,0.032621372,0.0037385419,0.0013559088,0.22541273],"study_design_scores_gemma":[0.0023779687,0.000894551,0.9840872,0.00022572046,0.00002003964,0.00001069544,0.0042577353,0.000019657344,0.0057076328,0.00018237591,0.0017121799,0.0005042352],"about_ca_topic_score_codex":0.0005198449,"about_ca_topic_score_gemma":0.0021623268,"teacher_disagreement_score":0.275508,"about_ca_system_score_codex":0.00012060056,"about_ca_system_score_gemma":0.0007921394,"threshold_uncertainty_score":0.9998682},"labels":[],"label_agreement":null},{"id":"W4407587936","doi":"10.1177/11786469241312475","title":"Preoperative Peripheral Blood Serotonin and Kynurenine Levels Are Associated With Oncological Outcomes in Glioblastoma IDH-wt Patients","year":2025,"lang":"en","type":"article","venue":"International Journal of Tryptophan Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Kynurenine; Medicine; Kynurenine pathway; Internal medicine; Proportional hazards model; Serotonin; Gastroenterology; Tryptophan; Glioblastoma; Oncology; Retrospective cohort study; Multivariate analysis; Endocrinology; Biology; Cancer research; Receptor","score_opus":0.049825046446631334,"score_gpt":0.37155351574891843,"score_spread":0.3217284693022871,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407587936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996092,0.000056845212,0.000024063494,0.0025134815,0.00022364873,0.00032924692,0.000030460045,0.000012490576,0.00071772095],"genre_scores_gemma":[0.9984503,0.000030338804,0.000108447864,0.0004262122,0.000043729797,0.000021121226,0.000001128927,0.0000117728005,0.0009069447],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9969328,0.0005876152,0.0004692576,0.00031277686,0.0013450009,0.00035255088],"domain_scores_gemma":[0.9977167,0.00096450525,0.00022483044,0.00010086685,0.00088163075,0.00011143635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005980759,0.00017083806,0.00033754762,0.0006977203,0.00012072367,0.00020021478,0.0006900373,0.00011292865,0.00016951791],"category_scores_gemma":[0.0038158416,0.00012016127,0.00007428903,0.0005713273,0.00033398176,0.00033870785,0.0002151175,0.00077817065,0.0000031990362],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024443767,0.003200722,0.9644781,0.0000157679,0.00028320315,0.0009904836,0.0010464814,0.0001401186,0.021187348,0.0020817667,0.00055104017,0.003580628],"study_design_scores_gemma":[0.007622746,0.0015145291,0.93330956,0.00034400047,0.0000069447183,0.000031704403,0.0004029209,0.00016037279,0.055273477,0.0010594608,0.00013324608,0.00014101376],"about_ca_topic_score_codex":0.000009538034,"about_ca_topic_score_gemma":0.00019055716,"teacher_disagreement_score":0.034086127,"about_ca_system_score_codex":0.0002574131,"about_ca_system_score_gemma":0.00023602627,"threshold_uncertainty_score":0.49000344},"labels":[],"label_agreement":null},{"id":"W4407609626","doi":"10.1101/2025.02.16.638530","title":"Microsporidia infection alters <i>C. elegans</i> lipid levels","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Microsporidia; Caenorhabditis elegans; Biology; Zoology; Ecology; Microbiology; Genetics; Spore; Gene","score_opus":0.020927379781144714,"score_gpt":0.23897898838623893,"score_spread":0.2180516086050942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407609626","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986992,0.00035858777,0.0019776537,0.0005108946,0.0066634608,0.0011609322,0.00080325484,0.0013342056,0.00019903596],"genre_scores_gemma":[0.9948017,0.0004752495,0.0007622359,0.0029369749,0.00063659536,0.00018293696,2.5617587e-7,0.00011338952,0.00009066993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99596626,0.0002550642,0.0006491285,0.0017878448,0.00048427642,0.00085740886],"domain_scores_gemma":[0.99735457,0.00017995133,0.00044064713,0.0015249396,0.00021058453,0.0002892865],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038424926,0.0007887062,0.00066465046,0.00049582304,0.00031420146,0.00041060912,0.0008889124,0.00068811263,0.000092110386],"category_scores_gemma":[0.0006423218,0.00089459197,0.0003235332,0.0010829996,0.0002531033,0.00028944394,0.00069119013,0.0012130195,0.00021129716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029457811,0.00017172968,0.0014832774,0.00040657682,0.000034908517,0.000029098832,0.000013664644,0.00009942761,0.99410564,0.00097045087,0.0026482986,0.0000074773484],"study_design_scores_gemma":[0.00057377684,0.000033868368,0.02394797,0.00033069827,0.000044455464,1.8591704e-8,9.653245e-7,0.000102130274,0.93031037,0.0000068296417,0.043772507,0.00087642926],"about_ca_topic_score_codex":0.0001273855,"about_ca_topic_score_gemma":0.000005724002,"teacher_disagreement_score":0.06379528,"about_ca_system_score_codex":0.0003150216,"about_ca_system_score_gemma":0.0008543891,"threshold_uncertainty_score":0.9993505},"labels":[],"label_agreement":null},{"id":"W4407636557","doi":"10.1016/j.psyneuen.2025.107406","title":"Exploring the dissociative subtype of PTSD: The role of early-life trauma, cortisol, and inflammatory profiles","year":2025,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Royal Ottawa Mental Health Centre; Carleton University","funders":"Ministère de la Défense Nationale; Canadian Armed Forces","keywords":"Dissociative; Psychology; Clinical psychology; Medicine","score_opus":0.04462033247187863,"score_gpt":0.275829283672934,"score_spread":0.2312089512010554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407636557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99285185,0.0005055256,0.000009406393,0.0018249832,0.00041831387,0.00035280292,0.000011988358,0.000037451195,0.003987646],"genre_scores_gemma":[0.99857825,0.0006681175,0.000007313472,0.0004715744,0.000022815146,0.00008123324,2.882528e-7,0.000011721263,0.0001586766],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986326,0.00030853826,0.0003180388,0.00030133445,0.00014371682,0.00029574207],"domain_scores_gemma":[0.99864966,0.0007364427,0.00019755676,0.0003494851,0.000035502184,0.000031382697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000436939,0.00013798568,0.00022112396,0.00010113406,0.00015328244,0.000012985321,0.00042995202,0.000020496169,0.00001370303],"category_scores_gemma":[0.00052949303,0.000087942135,0.00006788852,0.00033546035,0.0007649529,0.00010446331,0.00012974521,0.00024203176,0.0000060323996],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000692928,0.00032103856,0.1431722,0.000117590214,0.00010390977,0.000017067441,0.0068298755,0.000014072718,0.6331304,0.17269963,0.00082857616,0.042072725],"study_design_scores_gemma":[0.0006371435,0.00022643834,0.7011168,0.000021684133,0.000018116176,0.000010628374,0.0020157306,0.00002716831,0.2879507,0.0048469743,0.0030259644,0.00010266871],"about_ca_topic_score_codex":0.000045678735,"about_ca_topic_score_gemma":0.00003852526,"teacher_disagreement_score":0.5579446,"about_ca_system_score_codex":0.000005892285,"about_ca_system_score_gemma":0.000035438672,"threshold_uncertainty_score":0.3586176},"labels":[],"label_agreement":null},{"id":"W4407885594","doi":"10.1093/ijnp/pyaf012","title":"Altered proteomics in brain extracellular vesicles from depressed individuals who died by suicide implicates synaptic processes","year":2025,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Major depressive disorder; In silico; Proteomics; Neuroscience; Proteome; Biology; Synaptic vesicle; Bioinformatics; Psychology; Vesicle; Biochemistry; Gene; Cognition","score_opus":0.0222900225257127,"score_gpt":0.3218424716225411,"score_spread":0.2995524490968284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407885594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96781343,0.0010271408,0.0005467319,0.028831568,0.0011335766,0.00034269222,0.00005653802,0.000022612774,0.00022569444],"genre_scores_gemma":[0.98794353,0.000561208,0.00008347899,0.010996288,0.00019945911,0.00002866999,0.0000031909804,0.000020533327,0.00016363156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794376,0.00040601936,0.00068390084,0.00032313901,0.00037509794,0.00026809407],"domain_scores_gemma":[0.99696994,0.0021684272,0.0004926056,0.00015816891,0.00014779302,0.0000630958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031292613,0.00019116217,0.00027375494,0.00029071583,0.00007351916,0.00011489703,0.0018740813,0.000069015434,0.00009663307],"category_scores_gemma":[0.001333232,0.00014580744,0.00008658209,0.0003741179,0.00021280888,0.00022293098,0.00015974912,0.00051101,0.000012240747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007279397,0.00023686726,0.0014446768,0.000010372637,0.000095713796,0.000071774826,0.00022324074,0.00024687278,0.9803414,0.00017425847,0.014235882,0.0021910465],"study_design_scores_gemma":[0.004400586,0.0001376228,0.0152675705,0.000100281104,0.00003315795,0.00007942108,0.000078471494,0.00039456942,0.9593252,0.010272089,0.0097278245,0.00018323508],"about_ca_topic_score_codex":0.000023498584,"about_ca_topic_score_gemma":0.0000082248935,"teacher_disagreement_score":0.021016184,"about_ca_system_score_codex":0.000052727963,"about_ca_system_score_gemma":0.00015978892,"threshold_uncertainty_score":0.5945855},"labels":[],"label_agreement":null},{"id":"W4407933675","doi":"10.1016/j.brs.2024.12.561","title":"Influence of Biological Sex on the Efficacy of Neurostimulation in the Treatment of Major Depressive Disorder","year":2025,"lang":"en","type":"article","venue":"Brain stimulation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; Mental Health Research Canada; University of Ottawa; Université du Québec en Outaouais","funders":"","keywords":"Neurostimulation; Major depressive disorder; Medicine; Psychology; Clinical psychology; Neuroscience; Stimulation","score_opus":0.03340368919560202,"score_gpt":0.30901631227191867,"score_spread":0.2756126230763166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407933675","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975989,0.000032887634,0.00025772577,0.0009953963,0.000022714203,0.00071590627,0.000010809649,0.0000101891,0.00035550384],"genre_scores_gemma":[0.9994995,0.000015611922,0.000012231974,0.00040820235,0.0000062034906,0.000019953612,0.000004142239,0.0000038669987,0.000030300458],"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","domain_scores_codex":[0.9988618,0.00034951125,0.0003086481,0.00020229418,0.00017606429,0.00010166514],"domain_scores_gemma":[0.99460584,0.0049132924,0.0001722103,0.0002714964,0.000028707085,0.000008465714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013102357,0.00010173893,0.0001542854,0.00010690508,0.00005665639,0.0000067001147,0.00019925447,0.000053573265,0.000009673327],"category_scores_gemma":[0.0017541565,0.000054638956,0.00006408898,0.00053022866,0.00018427563,0.000046565387,0.000018508521,0.000051536754,0.0000013209826],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046089565,0.001257276,0.08684061,0.000023846549,0.000008050363,0.0000010912077,0.0018079957,0.6497187,0.23450685,0.015403272,0.000039050414,0.009932363],"study_design_scores_gemma":[0.0016526848,0.00039129768,0.90605104,0.00003454157,0.0000060978978,1.787984e-7,0.00007360244,0.010344778,0.079644755,0.0016446679,0.00010620449,0.0000501703],"about_ca_topic_score_codex":0.000043001826,"about_ca_topic_score_gemma":0.000008545385,"teacher_disagreement_score":0.8192104,"about_ca_system_score_codex":0.0000137152865,"about_ca_system_score_gemma":0.000025062058,"threshold_uncertainty_score":0.22281119},"labels":[],"label_agreement":null},{"id":"W4407979053","doi":"10.1101/2025.02.25.640229","title":"iPSC-Derived Cerebral Organoids Reveal Mitochondrial, Inflammatory and Neuronal Vulnerabilities in Bipolar Disorder","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Ontario Genomics; Toronto Western Hospital; University of Toronto; University Health Network","funders":"","keywords":"Bipolar disorder; Organoid; Neuroscience; Medicine; Biology","score_opus":0.011870509693734694,"score_gpt":0.2173452515218318,"score_spread":0.2054747418280971,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407979053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934858,0.0019020375,0.0000926576,0.00056844874,0.0019482047,0.0011503355,0.00036039975,0.00046950078,0.000022615712],"genre_scores_gemma":[0.9968005,0.0005784844,0.00081980246,0.00096675835,0.00036077618,0.0002748658,4.185783e-7,0.00012999639,0.00006839488],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9950545,0.00066536467,0.0008633884,0.001968742,0.00053986564,0.0009081821],"domain_scores_gemma":[0.99751705,0.00041424896,0.0003368349,0.0012936159,0.00014741915,0.0002908265],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003430682,0.00086732575,0.00082012557,0.00069165346,0.00029953822,0.00037145117,0.00093287416,0.0007136402,0.00009169854],"category_scores_gemma":[0.0017217558,0.0009561096,0.00017512334,0.0008131608,0.00062664645,0.00035139022,0.0012477312,0.0016392116,0.00003168026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000964989,0.00022594121,0.03144165,0.000834305,0.000026637133,0.000055307126,0.00008333813,0.00009519784,0.96501976,0.0016829496,0.00042771886,0.000010694428],"study_design_scores_gemma":[0.002718867,0.000107111104,0.31730792,0.0006991229,0.000055029574,7.067233e-8,0.00003082232,0.00048307894,0.6601303,0.000059897957,0.016425576,0.001982176],"about_ca_topic_score_codex":0.00010001306,"about_ca_topic_score_gemma":0.000038345388,"teacher_disagreement_score":0.30488944,"about_ca_system_score_codex":0.00021927744,"about_ca_system_score_gemma":0.0009677588,"threshold_uncertainty_score":0.9992889},"labels":[],"label_agreement":null},{"id":"W4408133680","doi":"10.2147/prbm.s501273","title":"The Interaction Between Family Functioning and the PCDH9 rs9540720 Polymorphism on Major Depressive Disorder in Chinese Freshmen","year":2025,"lang":"en","type":"article","venue":"Psychology Research and Behavior Management","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Major depressive disorder; Psychology; Polymorphism (computer science); Depressive symptoms; Clinical psychology; Psychiatry; Medicine; Genetics; Genotype; Gene; Mood; Biology; Cognition","score_opus":0.05251872771805942,"score_gpt":0.39913682208758783,"score_spread":0.3466180943695284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408133680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9743889,0.0006147761,0.00006525373,0.009315408,0.00028985512,0.000993611,0.000004217485,0.000025781143,0.014302185],"genre_scores_gemma":[0.99466014,0.0010568115,0.0000080983755,0.0008354334,0.000033618697,0.00057516724,0.0000024071862,0.0000098607525,0.0028184827],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99806225,0.0004930927,0.00021222566,0.00052854547,0.0002787097,0.00042516194],"domain_scores_gemma":[0.9986319,0.0008785824,0.00004293244,0.00037324458,0.00002260072,0.000050769642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007486041,0.0001417357,0.00014310947,0.00033871076,0.00083992636,0.00018085557,0.00035313892,0.00006257287,0.000018454217],"category_scores_gemma":[0.00015368455,0.000080213,0.00003268768,0.0005766494,0.000866141,0.000095491676,0.00033357518,0.00056055596,0.000018299874],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026875685,0.0008907169,0.34711295,0.00005521302,0.000080487225,0.000100955236,0.00071625604,0.0000044869726,0.005334294,0.025152387,0.00655485,0.6113098],"study_design_scores_gemma":[0.004178224,0.00015321422,0.9812501,0.000032121567,0.000018843728,0.0000031281845,0.0010721994,0.000028459452,0.00016254376,0.007091592,0.005914044,0.000095503754],"about_ca_topic_score_codex":0.00012816754,"about_ca_topic_score_gemma":0.00012851993,"teacher_disagreement_score":0.63413715,"about_ca_system_score_codex":0.00002659371,"about_ca_system_score_gemma":0.0000074375425,"threshold_uncertainty_score":0.64601195},"labels":[],"label_agreement":null},{"id":"W4408160809","doi":"10.3390/metabo15030176","title":"Metabolic Syndrome and Schizophrenia: Adding a Piece to the Interplay Between the Kynurenine Pathway and Inflammation","year":2025,"lang":"en","type":"review","venue":"Metabolites","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Neuroscience; Kynurenine pathway; Schizophrenia (object-oriented programming); Neuroinflammation; Neuroprotection; Context (archaeology); Glutamatergic; Central nervous system; Inflammation; Medicine; Biology; Kynurenine; Glutamate receptor; Immunology; Psychiatry; Internal medicine","score_opus":0.02534776878716227,"score_gpt":0.30366251046606635,"score_spread":0.2783147416789041,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408160809","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0025482797,0.99430454,0.000061185056,0.00065880234,0.00028054885,0.0014157983,0.00027274952,0.00008776165,0.0003703221],"genre_scores_gemma":[0.0038637025,0.99430364,0.00015705673,0.00031949734,0.000294669,0.00032430227,0.000023614602,0.000042655145,0.0006708821],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99719626,0.00074899005,0.00059675646,0.00073477655,0.00031335847,0.0004098456],"domain_scores_gemma":[0.996622,0.0023469755,0.0002649651,0.0006147233,0.000030249916,0.00012108738],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006490054,0.00053678494,0.0014024948,0.00037376102,0.00043696977,0.0004136389,0.00078941364,0.00016830105,0.000026118154],"category_scores_gemma":[0.002159102,0.00027161196,0.00023764234,0.0012386008,0.00022009427,0.00018849292,0.0006000876,0.00056090835,0.000050055067],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000048861,0.0000061893065,0.000008449789,0.0011780582,0.00006416041,0.000004059507,0.0002268796,2.7648505e-7,0.00009350785,0.007545778,0.0001325305,0.99073523],"study_design_scores_gemma":[0.00018327971,0.00002056773,0.0005074162,0.001850888,0.00046824728,0.00006443348,0.000027610227,0.000003192663,0.00045370046,0.00035678272,0.9957655,0.00029835026],"about_ca_topic_score_codex":0.000011144638,"about_ca_topic_score_gemma":0.0000124408025,"teacher_disagreement_score":0.995633,"about_ca_system_score_codex":0.0000121880075,"about_ca_system_score_gemma":0.000119188815,"threshold_uncertainty_score":0.9999736},"labels":[],"label_agreement":null},{"id":"W4408318200","doi":"10.1016/j.jad.2025.03.041","title":"Kynurenine pathway metabolites predict antianhedonic effects of electroconvulsive therapy in patients with treatment-resistant depression","year":2025,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Clinical Key Specialty Project Foundation; Guangzhou Municipal Science and Technology Project; Guangzhou Science and Technology Program key projects; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Electroconvulsive therapy; Kynurenine; Depression (economics); Kynurenine pathway; Treatment-resistant depression; Medicine; Psychiatry; Pharmacology; Psychology; Major depressive disorder; Cognition; Tryptophan; Biology","score_opus":0.003141890702281973,"score_gpt":0.221386058266992,"score_spread":0.21824416756471005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408318200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958884,0.0024308371,0.00022165493,0.00005513248,0.00015994624,0.0008321434,0.000009179598,0.00001353167,0.000389179],"genre_scores_gemma":[0.99851185,0.0012843944,0.000040284755,0.00007548347,0.000012762619,0.000022513743,0.0000018272142,0.00001981893,0.000031035554],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832135,0.00036663338,0.0003691464,0.00028836608,0.00034513068,0.00030934822],"domain_scores_gemma":[0.9984236,0.0007667037,0.00044479346,0.00017900158,0.00012488179,0.000061045874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010981563,0.0002647495,0.00051322614,0.0005353969,0.00007057731,0.000021801781,0.00023671718,0.00007339556,0.000009654695],"category_scores_gemma":[0.00048032746,0.00016927753,0.00017723862,0.0008742807,0.00015261484,0.00026822163,0.000022311302,0.00020849885,6.0947514e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0061351135,0.0032870087,0.46697754,0.00009542573,0.00028879053,0.000020047915,0.0007195906,0.00010878372,0.42543572,0.0003073729,0.000054266868,0.09657034],"study_design_scores_gemma":[0.010224245,0.0035689718,0.4797675,0.00016894314,0.0000287905,7.467677e-7,0.00007011904,0.000010011738,0.5055632,0.00037947187,0.0001126507,0.00010535969],"about_ca_topic_score_codex":0.000045234563,"about_ca_topic_score_gemma":0.00012772511,"teacher_disagreement_score":0.096464984,"about_ca_system_score_codex":0.000096692136,"about_ca_system_score_gemma":0.00020425576,"threshold_uncertainty_score":0.6902937},"labels":[],"label_agreement":null},{"id":"W4408422135","doi":"10.1016/j.bcp.2025.116872","title":"Loss of aryl hydrocarbon receptor reduces pancreatic tumor growth by increasing immune cell infiltration","year":2025,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Glycomics Network; EEA Grants; Canadian Institutes of Health Research; Direktør Throne Holsts Fond For Ernæringsforskning; Norges Forskningsråd; Associazione Italiana per la Ricerca sul Cancro; European Environment Agency","keywords":"Aryl hydrocarbon receptor; Immune system; Infiltration (HVAC); Hydrocarbon; Receptor; Chemistry; Cell growth; Cancer research; Biology; Cell biology; Immunology; Biochemistry; Materials science; Organic chemistry","score_opus":0.008674338724240241,"score_gpt":0.26050569625416753,"score_spread":0.2518313575299273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408422135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99468976,0.0010856162,0.000026559173,0.00074671634,0.00041081654,0.00026335687,0.000021171873,0.00007318524,0.0026827983],"genre_scores_gemma":[0.9980125,0.00018626249,0.00010002966,0.00143141,0.00005887005,0.00003088759,0.000018383786,0.000013382922,0.00014828921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867314,0.00012680926,0.00037469054,0.00039607615,0.00013745227,0.00029184928],"domain_scores_gemma":[0.9991462,0.0004713604,0.00015800406,0.00011925277,0.000033290107,0.00007184795],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013554304,0.00017196524,0.00026962537,0.00010847996,0.00006781405,0.00001285153,0.00031644444,0.000106678155,0.00016754869],"category_scores_gemma":[0.00039822972,0.00017037112,0.00007804768,0.0004475361,0.0003683204,0.00007962121,0.00009133642,0.00019888981,0.000019912644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029174748,0.0002759742,0.00014493463,0.00008026371,0.000009945734,0.0000025884826,0.0000384761,6.766735e-7,0.95289767,0.000116797826,0.046091333,0.000049597777],"study_design_scores_gemma":[0.0010402395,0.00006417972,0.00019501816,0.000025412599,0.000029519666,0.0000045517804,0.000027654221,0.000088700486,0.99743515,0.0003543694,0.0005886544,0.00014654419],"about_ca_topic_score_codex":0.00004596029,"about_ca_topic_score_gemma":5.3717752e-8,"teacher_disagreement_score":0.045502678,"about_ca_system_score_codex":0.000049561364,"about_ca_system_score_gemma":0.0000837514,"threshold_uncertainty_score":0.6947532},"labels":[],"label_agreement":null},{"id":"W4408569256","doi":"10.1016/j.jneuroim.2025.578587","title":"Peripheral and central inflammation in depression: How large is the gap and can we bridge it with PET neuroimaging and neural-derived extracellular vesicles?","year":2025,"lang":"en","type":"review","venue":"Journal of Neuroimmunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Queen's University; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Neuroscience; Neuroimaging; Extracellular vesicles; Peripheral; Bridge (graph theory); Inflammation; Depression (economics); Medicine; Psychology; Pathology; Biology; Anatomy; Cell biology; Immunology; Internal medicine","score_opus":0.03847832465819461,"score_gpt":0.28644144908990454,"score_spread":0.24796312443170992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408569256","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21114449,0.78060293,0.000015994396,0.007550608,0.00022052566,0.0004209109,0.000015383233,0.0000119712295,0.000017156215],"genre_scores_gemma":[0.104526825,0.89470494,0.000018091016,0.0005557185,0.000056251152,0.000007175086,0.0000013803899,0.00003002339,0.00009957838],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975621,0.00079616526,0.00054480997,0.00046253574,0.00019787719,0.00043648586],"domain_scores_gemma":[0.9983157,0.0006044232,0.0007081325,0.0002556188,0.00003648729,0.00007967363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001552904,0.00038166705,0.000907246,0.00029620342,0.00020683787,0.00023205097,0.00034468973,0.00011143005,0.000008521582],"category_scores_gemma":[0.00034332968,0.00024479447,0.00010901068,0.00030696052,0.00036055915,0.000290343,0.0002207903,0.0011240055,2.0150459e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025863783,0.00010703778,0.0011720582,0.004174846,0.00006941611,0.0030287732,0.002093859,0.0000063808347,0.036307838,0.0001370099,0.00031547033,0.9523287],"study_design_scores_gemma":[0.006831136,0.0010502896,0.13349319,0.0124065,0.00059989374,0.04045906,0.0008114155,0.0008791573,0.0005753292,0.00028955293,0.80129534,0.0013091447],"about_ca_topic_score_codex":0.0000055333335,"about_ca_topic_score_gemma":0.000021084446,"teacher_disagreement_score":0.9510195,"about_ca_system_score_codex":0.000028986706,"about_ca_system_score_gemma":0.00015627373,"threshold_uncertainty_score":0.9982429},"labels":[],"label_agreement":null},{"id":"W4408581439","doi":"10.1101/2025.03.17.643727","title":"Transcriptional Profiles of Antidepressant Resistance Across the Corticolimbic Pathway of Chronically Stressed Mice","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Treatment-resistant depression; Nucleus accumbens; Antidepressant; Fluoxetine; Major depressive disorder; Depression (economics); Pharmacology; Neuroscience; Psychology; Medicine; Internal medicine; Hippocampus; Receptor; Central nervous system; Serotonin; Amygdala","score_opus":0.019187239603095863,"score_gpt":0.2448816611631885,"score_spread":0.22569442156009262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408581439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919317,0.0019501477,0.00048324076,0.00037859296,0.0006966631,0.0011253607,0.0032261875,0.0001462062,0.00006193971],"genre_scores_gemma":[0.99834126,0.00047723408,0.0006196475,0.00023348321,0.00008058676,0.00016255923,3.0188738e-7,0.000047066875,0.000037885686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964734,0.00032887497,0.0009350566,0.0010100537,0.00069830334,0.0005543555],"domain_scores_gemma":[0.9969319,0.0004284794,0.00080546224,0.0013310069,0.00039596437,0.000107176245],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046163783,0.00045332804,0.0006684081,0.00012179262,0.00020304172,0.000094200484,0.0014697651,0.0003587892,0.000038915157],"category_scores_gemma":[0.0008658496,0.00038523087,0.00029405626,0.0006757519,0.00087774574,0.00011401701,0.00042407736,0.0006900581,0.000004708023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015573128,0.00033596437,0.0010512739,0.001384749,0.000052834155,0.000012763099,0.00004107161,0.00013125667,0.9894483,0.0072350046,0.00014893104,0.0000021252647],"study_design_scores_gemma":[0.0006162513,0.000032615088,0.13686551,0.0008247257,0.000033049888,6.469913e-9,0.000009484798,0.00011069115,0.8595824,0.000014332418,0.0015872404,0.00032367551],"about_ca_topic_score_codex":0.00003391453,"about_ca_topic_score_gemma":0.00002141605,"teacher_disagreement_score":0.13581423,"about_ca_system_score_codex":0.00008207032,"about_ca_system_score_gemma":0.0012092836,"threshold_uncertainty_score":0.99986},"labels":[],"label_agreement":null},{"id":"W4408606296","doi":"10.1016/j.bbi.2025.03.023","title":"Large-scale effects of prenatal inflammation and early life circadian disruption in mice: Implications for neurodevelopmental disorders","year":2025,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Velux Stiftung; Canada First Research Excellence Fund; McGill University; American College of Neuropsychopharmacology","keywords":"Circadian rhythm; Inflammation; Prenatal stress; Medicine; Neuroscience; Prenatal exposure; Psychology; Pregnancy; Biology; Internal medicine; Gestation; Genetics","score_opus":0.011320169168898494,"score_gpt":0.27342056779009877,"score_spread":0.26210039862120027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408606296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977563,0.000103165374,0.00037187472,0.00066746783,0.000066897126,0.0008835951,0.000040725292,0.000024445995,0.00008553892],"genre_scores_gemma":[0.9994436,0.000066756285,0.00007714898,0.00011696414,0.000004152839,0.0002056676,0.00001816027,0.00000794578,0.0000596292],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992753,0.000087375396,0.00021061918,0.00021377066,0.00004675912,0.00016613214],"domain_scores_gemma":[0.9994413,0.00030865634,0.000060669277,0.00012844284,0.000013115344,0.00004778814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001208271,0.00010013753,0.00012814117,0.000162751,0.00018413943,0.000032642693,0.000106535445,0.00006423332,0.0000017807608],"category_scores_gemma":[0.0004469386,0.00010910727,0.00003136648,0.00023690265,0.00011945537,0.00020989927,0.00007548871,0.000110277266,3.606719e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005717936,0.00033502805,0.20863377,0.00028046762,0.00000322839,3.1918987e-7,0.0041069253,6.6798793e-7,0.7369956,0.0022195927,0.000045718618,0.047321502],"study_design_scores_gemma":[0.0012598647,0.00005872805,0.94478905,0.00003771518,0.0000078988105,9.637422e-7,0.00027156444,0.000022701337,0.052683014,0.0006676114,0.000105624684,0.00009524861],"about_ca_topic_score_codex":0.00007453183,"about_ca_topic_score_gemma":0.0001792622,"teacher_disagreement_score":0.7361553,"about_ca_system_score_codex":0.000014760899,"about_ca_system_score_gemma":0.000034623412,"threshold_uncertainty_score":0.44492653},"labels":[],"label_agreement":null},{"id":"W4408766975","doi":"10.1101/2025.03.21.25324400","title":"The association of NLRP3 polymorphisms and its downstream interaction in mild cognitive impairment","year":2025,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Health and Medical Research Fund","keywords":"Cognitive impairment; Association (psychology); Downstream (manufacturing); Cognition; Psychology; Medicine; Neuroscience; Engineering; Psychotherapist; Operations management","score_opus":0.022767789111604382,"score_gpt":0.28527235409802093,"score_spread":0.26250456498641656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408766975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943409,0.00032142113,0.000008492514,0.001210806,0.0007022802,0.0005107872,0.00007866091,0.000026082287,0.0028005608],"genre_scores_gemma":[0.9976993,0.00078210793,0.000004248765,0.00022740265,0.00002662001,0.00006497083,0.000005729535,0.0000066930215,0.0011828837],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986281,0.00026325524,0.00029693535,0.00036992875,0.00024992574,0.00019190002],"domain_scores_gemma":[0.9984797,0.0009847449,0.0003115121,0.0001438726,0.000049527927,0.000030643394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034712986,0.00015544018,0.00019846826,0.00015161945,0.00007633968,0.000046878653,0.00019395596,0.00014854944,0.000015574691],"category_scores_gemma":[0.0011314253,0.000121776626,0.0000711332,0.00020107027,0.000050421022,0.00005955273,0.0002900549,0.0004087517,0.00000723473],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025012668,0.0030845036,0.6565339,0.0016789128,0.0004028412,0.00006961749,0.017680796,0.00042184198,0.21701282,0.008981711,0.00323826,0.08839355],"study_design_scores_gemma":[0.0016679409,0.00011752021,0.51338637,0.0009482881,0.000041611125,0.0000025529243,0.00069440005,0.0013187263,0.47869638,0.0021032789,0.000683165,0.00033975832],"about_ca_topic_score_codex":0.00006556415,"about_ca_topic_score_gemma":0.00016959068,"teacher_disagreement_score":0.26168355,"about_ca_system_score_codex":0.000117393174,"about_ca_system_score_gemma":0.000076900375,"threshold_uncertainty_score":0.49659064},"labels":[],"label_agreement":null},{"id":"W4408840484","doi":"10.58837/chula.the.2023.659","title":"The neuro-immune pathogenesis of mild cognitive impairment","year":2023,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Cognitive impairment; Pathogenesis; Cognition; Immune system; Neuroscience; Medicine; Psychology; Cognitive science; Immunology","score_opus":0.025244100069933467,"score_gpt":0.28254691111972463,"score_spread":0.25730281104979114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408840484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781168,0.00035856888,0.0000038187877,0.0001965436,0.0015620393,0.0008126487,0.00008539185,0.00017992765,0.018684277],"genre_scores_gemma":[0.93093395,0.0014803738,0.000006420413,0.00037657158,0.000042135205,0.00013252022,0.00012200221,0.000080504265,0.06682553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984835,0.00012738735,0.00034530277,0.00038848195,0.00038501163,0.00027034184],"domain_scores_gemma":[0.9981047,0.0013130691,0.00022371445,0.00025142744,0.00006556132,0.000041522406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012572492,0.00021712731,0.00021998996,0.00010041335,0.0002234867,0.000042387965,0.0003772148,0.00011393369,0.00010092202],"category_scores_gemma":[0.0007537174,0.0001458059,0.00020737591,0.00042621727,0.00009013493,0.000034342604,0.000043935306,0.00016209511,0.00020620004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011977245,0.0005159663,0.00011928955,0.00046901897,0.00008714773,0.000063060645,0.0036139938,0.000006639752,0.9162459,0.0039287065,0.008933567,0.06481904],"study_design_scores_gemma":[0.0007499134,0.00023494783,0.1164578,0.0001673842,0.000045359106,0.0000020613113,0.009648207,0.000045699086,0.87059975,0.00071029307,0.0009707483,0.00036786092],"about_ca_topic_score_codex":0.00005167656,"about_ca_topic_score_gemma":0.000196144,"teacher_disagreement_score":0.11633851,"about_ca_system_score_codex":0.000010476578,"about_ca_system_score_gemma":0.00008543512,"threshold_uncertainty_score":0.5945792},"labels":[],"label_agreement":null},{"id":"W4408854571","doi":"10.1038/s41537-025-00603-3","title":"External stress, formaldehyde, and schizophrenia: a new mouse model for mental illness research","year":2025,"lang":"en","type":"article","venue":"Schizophrenia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Natural Science Foundation of China","keywords":"Ventral tegmental area; Anhedonia; Open field; Schizophrenia (object-oriented programming); Prefrontal cortex; Elevated plus maze; Dopamine; NMDA receptor; Psychology; Prepulse inhibition; Neuroscience; Internal medicine; Endocrinology; Chemistry; Anxiety; Medicine; Psychiatry; Dopaminergic; Receptor; Cognition","score_opus":0.046343268697812544,"score_gpt":0.33050513830942546,"score_spread":0.28416186961161294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408854571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.984024,0.00063544005,0.010357271,0.0015054853,0.0003833572,0.0011642572,0.00026879463,0.00019769491,0.0014637306],"genre_scores_gemma":[0.9777439,0.0002383853,0.0062874365,0.00054451823,0.0001509471,0.0001330355,0.000010210325,0.000043295964,0.01484827],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99751294,0.0001090589,0.0003246299,0.0007920853,0.0004922982,0.0007690042],"domain_scores_gemma":[0.998873,0.00029195956,0.000064230066,0.0004517617,0.0000669615,0.0002520792],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003239974,0.0002818009,0.00027255798,0.00039928753,0.0008194424,0.00029132655,0.00062936905,0.00014925851,0.000039007828],"category_scores_gemma":[0.00045131255,0.00026325378,0.00011474812,0.0005394464,0.0003574819,0.00045533018,0.00039761013,0.0004496421,0.000028214437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0095534315,0.00043025168,0.00029180865,0.0002862232,0.000040615516,0.000012426598,0.0017023165,0.00039161893,0.6122658,0.17681912,0.03156945,0.16663691],"study_design_scores_gemma":[0.015530797,0.00024002968,0.0008466104,0.00025966362,0.000026045718,0.000015952872,0.00043523402,0.096612535,0.7419347,0.13787454,0.005360623,0.000863261],"about_ca_topic_score_codex":0.000045101155,"about_ca_topic_score_gemma":0.0002076303,"teacher_disagreement_score":0.16577366,"about_ca_system_score_codex":0.00005956548,"about_ca_system_score_gemma":0.00039465632,"threshold_uncertainty_score":0.99998194},"labels":[],"label_agreement":null},{"id":"W4408914605","doi":"10.21203/rs.3.rs-5975731/v1","title":"Neuroanatomical dimensions in major depression: external validation and links with cognition, adverse life events, self-harm, metabolomics and genetics","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Calgary; McMaster University","funders":"","keywords":"Harm; Cognition; Depression (economics); Psychology; Do no harm; Psychiatry; Clinical psychology; Social psychology","score_opus":0.043221580875123344,"score_gpt":0.35084993866930597,"score_spread":0.3076283577941826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408914605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955869,0.0016804847,0.00019023914,0.0006115335,0.00011506038,0.0012893518,0.00017612189,0.00007298955,0.0002773674],"genre_scores_gemma":[0.99190366,0.0063380054,0.0010296591,0.0003164383,0.00005994763,0.00014781067,0.000034315148,0.000029237674,0.00014091915],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99643093,0.0009439483,0.00033109344,0.0010246553,0.0007903365,0.00047903258],"domain_scores_gemma":[0.9982087,0.0007688312,0.000095468306,0.00042178438,0.00019437462,0.00031081922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051364396,0.00027121356,0.00031738443,0.00055073824,0.00027018602,0.00011886161,0.0003188988,0.0004038015,0.000047854257],"category_scores_gemma":[0.001045765,0.00023832571,0.000050345196,0.00047568863,0.00025274252,0.00011469737,0.0013506318,0.0020762375,0.000008857873],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009215582,0.008548146,0.69545686,0.016153315,0.0006273851,0.0020041903,0.012093212,0.0076284925,0.19107287,0.009345112,0.006154372,0.041700482],"study_design_scores_gemma":[0.018453853,0.00080815493,0.6860233,0.006224796,0.0003436048,0.00017774283,0.0020925484,0.04716519,0.21062829,0.02031439,0.005133301,0.002634864],"about_ca_topic_score_codex":0.000035438476,"about_ca_topic_score_gemma":0.000025973059,"teacher_disagreement_score":0.0395367,"about_ca_system_score_codex":0.00004886466,"about_ca_system_score_gemma":0.00046165392,"threshold_uncertainty_score":0.971864},"labels":[],"label_agreement":null},{"id":"W4409055516","doi":"10.12809/eaap2502","title":"Cognitive impairment and elevated neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio in schizophrenia","year":2025,"lang":"en","type":"article","venue":"East Asian Archives of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Lymphocyte; Monocyte; Schizophrenia (object-oriented programming); Immunology; Cognitive impairment; Neutrophil to lymphocyte ratio; Cognition; Medicine; Psychology; Psychiatry","score_opus":0.009619645400554799,"score_gpt":0.25307078621705753,"score_spread":0.24345114081650274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409055516","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98417616,0.00065617816,0.0024625626,0.005665243,0.00050210644,0.0013162789,0.00009989634,0.00010735206,0.0050142105],"genre_scores_gemma":[0.99450934,0.00010199666,0.0029176548,0.002005268,0.000065555345,0.0000698195,0.0000072193097,0.000031354677,0.00029177824],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99772966,0.00022526413,0.0005087381,0.0008482491,0.00021437106,0.00047369167],"domain_scores_gemma":[0.99912417,0.00013144963,0.00012866077,0.0003159488,0.00001835337,0.0002813992],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000097299686,0.00035249427,0.00040353305,0.00082692894,0.00018011975,0.00009396714,0.0003061354,0.000070341724,0.000014595438],"category_scores_gemma":[0.0001489697,0.00035924136,0.0000831304,0.0008348516,0.00032052922,0.00016310849,0.0002577818,0.00020148883,0.000023167284],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02927845,0.0025622793,0.048136827,0.0011030252,0.00025251665,0.00008550832,0.027171953,0.0007481789,0.56207037,0.08168194,0.0014355439,0.24547343],"study_design_scores_gemma":[0.020788556,0.0011808218,0.8948003,0.0014552053,0.00005399065,0.000042476477,0.005140081,0.0048652324,0.056518734,0.01362549,0.0004761756,0.0010529467],"about_ca_topic_score_codex":0.00003224451,"about_ca_topic_score_gemma":0.00024359538,"teacher_disagreement_score":0.8466635,"about_ca_system_score_codex":0.000036301055,"about_ca_system_score_gemma":0.00042589486,"threshold_uncertainty_score":0.999886},"labels":[],"label_agreement":null},{"id":"W4409088228","doi":"10.1097/tp.0000000000005391","title":"Harnessing TDO2-mediated Metabolism to Modulate Immune Rejection in Liver Transplantation","year":2025,"lang":"en","type":"article","venue":"Transplantation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Immune system; Transplantation; Immunology; Liver transplantation; Metabolism; Medicine; Biology; Internal medicine","score_opus":0.01562421348579433,"score_gpt":0.2577350124010839,"score_spread":0.24211079891528955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409088228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9705703,0.00009731629,0.02493082,0.00046246647,0.00042281914,0.0004535168,0.00003577386,0.00015553241,0.002871419],"genre_scores_gemma":[0.99738216,0.0012385034,0.00026256463,0.00072801777,0.000019160825,0.000045374145,0.000073309806,0.000014893435,0.00023601708],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986759,0.00016011785,0.00032727318,0.0003903285,0.00019360984,0.00025280958],"domain_scores_gemma":[0.99959177,0.00016181945,0.000052030286,0.00012737536,0.000022961194,0.000044040724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015445519,0.00015743656,0.00016871373,0.0005041232,0.00012418437,0.0000564786,0.00013330288,0.000092558425,0.000039267416],"category_scores_gemma":[0.000051860497,0.00016538467,0.000052995078,0.001049531,0.00003473087,0.00039949612,0.0000043283217,0.00014938002,0.00007740866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000611406,0.00009142836,0.00018942723,0.00025680813,0.0000050053973,0.00008084552,0.005148455,0.0024855898,0.97702086,0.0019102126,0.000016889651,0.012183086],"study_design_scores_gemma":[0.002459647,0.000026798127,0.29235354,0.00021210633,0.00003901593,0.000022049251,0.00012435096,0.004197212,0.6994278,0.0006801897,0.00021346632,0.00024383108],"about_ca_topic_score_codex":0.00026183727,"about_ca_topic_score_gemma":0.0002981377,"teacher_disagreement_score":0.29216412,"about_ca_system_score_codex":0.00004238176,"about_ca_system_score_gemma":0.000039700953,"threshold_uncertainty_score":0.6744191},"labels":[],"label_agreement":null},{"id":"W4409105969","doi":"10.1016/j.pnpbp.2025.111356","title":"Investigating the disconnection between cytokine and symptom clusters in clinical high risk populations: Towards a comprehensive cross-dimensional analysis","year":2025,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Science and Technology Planning Project of Shenzhen Municipality; National Key Research and Development Program of China; Qingdao Municipal Science and Technology Bureau; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China","keywords":"Disconnection; Data science; Medicine; Psychology; Computer science; Political science","score_opus":0.06192673871654735,"score_gpt":0.4032066177025292,"score_spread":0.34127987898598183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409105969","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98905176,0.0011576345,0.000028910521,0.0076640663,0.0013634879,0.0005925511,0.00004065271,0.000062759886,0.00003820305],"genre_scores_gemma":[0.9916752,0.00047146808,0.00038807292,0.0072264164,0.00012639206,0.00008508466,0.000013511921,0.000007726863,0.0000061498554],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99629545,0.0014391445,0.0007945082,0.0009652169,0.00012778789,0.00037787354],"domain_scores_gemma":[0.9977408,0.0016842014,0.0002577585,0.00018843538,0.00002738872,0.000101433616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056026026,0.00026415108,0.00048140722,0.00035698665,0.00037756166,0.00007005011,0.00028320178,0.00029469485,0.000019646322],"category_scores_gemma":[0.0004912356,0.00017388648,0.00012893429,0.0014985123,0.0017561764,0.00010770127,0.00024398437,0.00096629653,0.0000017156599],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031982985,0.00022034456,0.9888756,0.000017174596,0.000059438706,0.0000052794635,0.000035138037,0.00023353414,0.00007987812,0.0011032493,0.00008596207,0.008964566],"study_design_scores_gemma":[0.0031948106,0.00019765846,0.98298323,0.00002427897,0.00009289876,0.0000047668655,0.000046897523,0.0023322776,0.000015080326,0.01083052,0.00010040253,0.00017719793],"about_ca_topic_score_codex":0.000032996777,"about_ca_topic_score_gemma":0.0000771311,"teacher_disagreement_score":0.00972727,"about_ca_system_score_codex":0.000015246999,"about_ca_system_score_gemma":0.00004142694,"threshold_uncertainty_score":0.7090885},"labels":[],"label_agreement":null},{"id":"W4409130990","doi":"10.1371/journal.pone.0320561","title":"Depression as a risk factor for Alzheimer’s disease: A human post-mortem study","year":2025,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Bell (Canada)","funders":"Elizabeth Blackwell Institute for Health Research, University of Bristol; Alzheimer's Society; Alzheimer Society; Wellcome Trust","keywords":"Neuroinflammation; Depression (economics); Dementia; Medicine; Alzheimer's disease; Interleukin 6; Internal medicine; Disease; Pathology; Psychology; Endocrinology; Cytokine","score_opus":0.08290201914365163,"score_gpt":0.320002485310762,"score_spread":0.23710046616711034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409130990","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99623406,0.0002899341,0.00002057529,0.00027732024,0.000057956826,0.001723425,0.00022092497,0.000182621,0.0009931743],"genre_scores_gemma":[0.9974647,0.000014960872,0.000058012327,0.0007095216,0.000035772362,0.0002386465,0.000004596095,0.000020722277,0.0014530563],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986459,0.00010757448,0.00018120103,0.0004957563,0.00031547097,0.0002540795],"domain_scores_gemma":[0.99913096,0.00023416552,0.00007560969,0.00039110275,0.00004899754,0.00011917526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005906648,0.0001518435,0.0001960334,0.000109020526,0.00034925836,0.000063991996,0.00030453518,0.000038340746,0.00022614202],"category_scores_gemma":[0.0009517635,0.00013342321,0.000080708305,0.00019733809,0.000048287267,0.0001080599,0.00011211258,0.00012344174,0.00005770787],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088860444,0.027977368,0.094966196,0.00017757148,0.00040887785,0.000038771905,0.0016049993,0.0000034952232,0.8576683,0.0009490748,0.00066355773,0.014653225],"study_design_scores_gemma":[0.0038830386,0.00094457547,0.6325542,0.00021591801,0.00062670175,2.7790531e-7,0.0005289787,0.00029263386,0.35775086,0.0022544658,0.0004875384,0.00046081655],"about_ca_topic_score_codex":0.00003285077,"about_ca_topic_score_gemma":0.000035549783,"teacher_disagreement_score":0.537588,"about_ca_system_score_codex":0.000015346212,"about_ca_system_score_gemma":0.00005702682,"threshold_uncertainty_score":0.5440841},"labels":[],"label_agreement":null},{"id":"W4409280662","doi":"10.1016/j.biopsych.2025.02.402","title":"165. Discovery and Validation of Novel Immune Biotypes in Major Depression","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of British Columbia; Centre for Addiction and Mental Health; University of Ottawa; McGill University; University of Calgary; Dalhousie University; University Health Network; University of Toronto; Queen's University; McMaster University","funders":"","keywords":"Depression (economics); Psychology; Neuroscience; Medicine; Computational biology; Biology; Economics","score_opus":0.027063200794444853,"score_gpt":0.28646489879848896,"score_spread":0.2594016980040441,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409280662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957222,0.00080332364,0.00047702465,0.00065446773,0.00037516712,0.00012900693,0.0000109443945,0.000022974138,0.0018049353],"genre_scores_gemma":[0.9988975,0.00010845526,0.000480933,0.0003933822,0.000015477666,0.0000051621173,0.0000030537128,0.000002440944,0.000093602255],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99933094,0.00005089264,0.00019009072,0.00026212898,0.00005235642,0.00011361142],"domain_scores_gemma":[0.99969137,0.00011513417,0.000054142118,0.00011862543,0.000004890848,0.000015829164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000079670805,0.00007836449,0.0001239108,0.00008082214,0.000037543326,0.00001579732,0.00012396504,0.000099554105,0.0000138398],"category_scores_gemma":[0.00022187337,0.000052867006,0.000036242865,0.00024776036,0.0001237994,0.000078085,0.000079574456,0.000081713944,0.000002031312],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014193101,0.000340748,0.18559308,0.000028564365,0.0000020380621,2.8393893e-7,0.000013112471,0.000005020438,0.79461265,0.017692022,0.000098148426,0.0014723906],"study_design_scores_gemma":[0.0012838126,0.00008052346,0.7693095,0.000087351014,0.0000025851898,0.0000012764234,0.00007731567,0.00004582831,0.22003518,0.008738737,0.00022761893,0.00011026569],"about_ca_topic_score_codex":0.000015622854,"about_ca_topic_score_gemma":0.0000056590657,"teacher_disagreement_score":0.5837164,"about_ca_system_score_codex":0.0000052800106,"about_ca_system_score_gemma":0.000019944897,"threshold_uncertainty_score":0.2155854},"labels":[],"label_agreement":null},{"id":"W4409280668","doi":"10.1016/j.biopsych.2025.02.290","title":"53. Brain Fatty Acid Amide Hydrolase Levels and Early Traumatic Experiences in Social Anxiety Disorder: A Preliminary Positron Emission Tomography Study With [11C]CURB","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Fatty acid amide hydrolase; Positron emission tomography; Anxiety; Psychology; Medicine; Psychiatry; Neuroscience; Internal medicine","score_opus":0.024003418537270213,"score_gpt":0.2822078049029949,"score_spread":0.2582043863657247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409280668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99580455,0.00064371096,0.00013228819,0.0017626089,0.00019336413,0.0008952065,0.0000103403645,0.00012924902,0.00042866543],"genre_scores_gemma":[0.9983995,0.000018197014,0.00025647934,0.0010626859,0.0000409533,0.00017218817,0.0000018062518,0.000010836145,0.00003734042],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9977148,0.00043220902,0.0003696298,0.0008367235,0.00021600645,0.00043060427],"domain_scores_gemma":[0.9994031,0.00017225892,0.00010676936,0.00020992607,0.000011191066,0.00009673303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021630655,0.00030668476,0.0003511064,0.00018721777,0.00039567353,0.00008057818,0.00036398432,0.00018710775,0.000025100384],"category_scores_gemma":[0.0001393418,0.00020278462,0.00010097664,0.00087152806,0.00043037513,0.0001585948,0.00013165154,0.0003141068,0.0000022772897],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015389953,0.0020479083,0.96213466,0.00004775245,0.000013944695,0.000009520317,0.0059637865,0.0000016551387,0.02249351,0.00040038902,0.0003402562,0.0050076214],"study_design_scores_gemma":[0.0020378383,0.0024722335,0.9792677,0.00006659588,0.000008882941,0.0000053472468,0.012038218,0.00004052039,0.001771396,0.00191605,0.00007115052,0.0003040638],"about_ca_topic_score_codex":0.000030080279,"about_ca_topic_score_gemma":0.000057840876,"teacher_disagreement_score":0.020722114,"about_ca_system_score_codex":0.00001710145,"about_ca_system_score_gemma":0.000051436975,"threshold_uncertainty_score":0.8269317},"labels":[],"label_agreement":null},{"id":"W4409281214","doi":"10.1016/j.biopsych.2025.02.745","title":"506. Analyzing Immune Genes in Schizophrenia: Linking PRS, Expression, and Subtype Differentiation","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia (object-oriented programming); Immune system; Gene; Gene expression; Psychology; Biology; Genetics; Psychiatry","score_opus":0.022398828453941207,"score_gpt":0.2682882348492482,"score_spread":0.245889406395307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409281214","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99322623,0.0041401316,0.00047535484,0.00074273185,0.00063046766,0.00015101675,0.0000029115497,0.000080632904,0.0005505245],"genre_scores_gemma":[0.9982353,0.00048125052,0.0007082464,0.00044333065,0.00006581692,0.000011464133,0.000005191576,0.0000049789846,0.000044409004],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989076,0.00014218695,0.00025034015,0.00041890994,0.00006949957,0.00021144372],"domain_scores_gemma":[0.9996096,0.000121612036,0.0000703531,0.00015486797,0.000008818764,0.000034746954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010404551,0.00013297124,0.00017200017,0.00013998579,0.00014298566,0.000045750447,0.00017985767,0.00015697762,0.000039046405],"category_scores_gemma":[0.00018417479,0.00009525685,0.000051997682,0.00037482363,0.00009208767,0.00006652483,0.00011748469,0.00019138992,0.000009125559],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013363776,0.00015000055,0.43492258,0.000031702726,0.0000035790633,0.0000014168346,0.000030918058,0.000005093008,0.5391232,0.0175823,0.00009602147,0.007919569],"study_design_scores_gemma":[0.0010333834,0.000049117632,0.94645184,0.00013730618,0.0000036469496,0.0000014142116,0.00006859876,0.00014330678,0.022937687,0.028710682,0.00028357893,0.00017944736],"about_ca_topic_score_codex":0.0000066009475,"about_ca_topic_score_gemma":0.000012077909,"teacher_disagreement_score":0.5161855,"about_ca_system_score_codex":0.000011259474,"about_ca_system_score_gemma":0.000028066826,"threshold_uncertainty_score":0.38844618},"labels":[],"label_agreement":null},{"id":"W4409281432","doi":"10.1016/j.biopsych.2025.02.331","title":"94. Elevated C-reactive Protein is Associated With Suicide Attempts in Youth With Bipolar Disorder","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Queen's University; Centre for Addiction and Mental Health","funders":"","keywords":"Bipolar disorder; Medicine; Psychiatry; Psychology; Clinical psychology; Internal medicine; Lithium (medication)","score_opus":0.028566924942884278,"score_gpt":0.26494810216645853,"score_spread":0.23638117722357427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409281432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945833,0.00035710097,0.00011146309,0.0019472451,0.00011896546,0.00083879457,0.00008082541,0.00019729105,0.0017650193],"genre_scores_gemma":[0.99578995,0.000009379205,0.00013935674,0.0034824384,0.000019494715,0.00006182297,0.0000252906,0.000018160375,0.00045411935],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979341,0.0002704496,0.00027486312,0.00078248524,0.00021397336,0.00052415376],"domain_scores_gemma":[0.9993141,0.00014252788,0.00013925748,0.00028918605,0.00003683439,0.000078091034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001466937,0.00030867438,0.00033344812,0.0001654909,0.00014507672,0.00004191244,0.00034886054,0.00024834488,0.00007783674],"category_scores_gemma":[0.00034288657,0.00018434713,0.00006607712,0.0014139634,0.0003194484,0.000100659294,0.00006395895,0.00043392056,0.000029600815],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013555505,0.0015253209,0.9395721,0.000020064492,0.000054639728,0.000020442356,0.00030339343,0.000010267055,0.052005157,0.0040624794,0.0003687603,0.00070183486],"study_design_scores_gemma":[0.0059579997,0.0016188712,0.95675635,0.000586662,0.00002548765,0.000004599559,0.0013661844,0.00005862551,0.026777307,0.004549603,0.00141042,0.0008878745],"about_ca_topic_score_codex":0.0001531061,"about_ca_topic_score_gemma":0.0005607834,"teacher_disagreement_score":0.025227848,"about_ca_system_score_codex":0.000056191853,"about_ca_system_score_gemma":0.00015145916,"threshold_uncertainty_score":0.75174576},"labels":[],"label_agreement":null},{"id":"W4409281459","doi":"10.1016/j.biopsych.2025.02.517","title":"279. The Systemic Immune-Inflammation Index (SII) as a Biomarker for Depression in a Community Sample of Adolescents","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Biomarker; Systemic inflammation; Depression (economics); Inflammation; Medicine; Immune system; Psychology; Index (typography); Sample (material); Immunology; Clinical psychology; Internal medicine; Biology; Chemistry; Computer science","score_opus":0.03713849469989444,"score_gpt":0.3133370140606345,"score_spread":0.2761985193607401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409281459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956404,0.0004192168,0.0015205919,0.0005036568,0.0005047672,0.00073714356,0.000020912066,0.000042242144,0.0006110504],"genre_scores_gemma":[0.99920464,0.000036441095,0.0000855517,0.00055529596,0.00001911318,0.000069461305,0.000006984741,0.0000046409255,0.000017877224],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985988,0.00056310336,0.00035544735,0.0002030557,0.00009082948,0.00018876034],"domain_scores_gemma":[0.99885577,0.00063301896,0.00013910956,0.0003301541,0.000020303829,0.000021636795],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042983334,0.000116009585,0.00017675904,0.00008568537,0.00019228422,0.000016431019,0.00048266604,0.00015758903,0.000013055233],"category_scores_gemma":[0.0011962048,0.00006820067,0.00010662608,0.00036314875,0.00015322198,0.000040012903,0.00013207132,0.00022290983,0.000004828629],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011438247,0.00052795926,0.660923,0.00037252068,0.000009143296,2.875699e-7,0.00017403127,0.000012384164,0.32154813,0.0059409835,0.00045498254,0.00889273],"study_design_scores_gemma":[0.0016736126,0.000110617904,0.95790076,0.00059758517,0.000004347582,0.0000027608228,0.00074149464,0.0004580151,0.011938643,0.026133643,0.00031214196,0.00012636113],"about_ca_topic_score_codex":0.0001350537,"about_ca_topic_score_gemma":0.000056859182,"teacher_disagreement_score":0.3096095,"about_ca_system_score_codex":0.000020947156,"about_ca_system_score_gemma":0.00005017981,"threshold_uncertainty_score":0.2781143},"labels":[],"label_agreement":null},{"id":"W4409289907","doi":"10.37275/scipsy.v6i2.186","title":"The Eye as a Window to Neuroinflammation in Psychiatric Disorders?: A Meta-Analysis of Retinal Structural and Vascular Biomarkers","year":2025,"lang":"en","type":"article","venue":"Scientia Psychiatrica","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Neuroinflammation; Retinal; Window (computing); Meta-analysis; Medicine; Neuroscience; Psychiatry; Ophthalmology; Psychology; Internal medicine; Inflammation; Computer science; World Wide Web","score_opus":0.012674927907869489,"score_gpt":0.2868732052920156,"score_spread":0.2741982773841461,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409289907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98406756,0.0015750201,0.00031829768,0.00903584,0.0006003863,0.0007364716,0.000017594948,0.00003797955,0.0036108764],"genre_scores_gemma":[0.99860877,0.00011404318,0.0005421178,0.00042259358,0.000010470235,0.00003103608,0.0000020127748,0.000009149053,0.00025981988],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.9975283,0.00031979714,0.0005132641,0.0007363518,0.0005240811,0.00037816746],"domain_scores_gemma":[0.99884033,0.000257946,0.00018771591,0.0005816027,0.00003948643,0.00009290468],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005970579,0.00020515149,0.00042700054,0.0017051973,0.00041235116,0.00016218847,0.0005935868,0.000054470333,0.00007187908],"category_scores_gemma":[0.00045411751,0.00014211034,0.0006144783,0.011561311,0.0002575299,0.000136757,0.00013666556,0.00013916656,0.0000086684795],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032531575,0.0017389884,0.3492671,0.000673539,0.06352809,0.000016418637,0.008554628,0.013209127,0.12866165,0.36909166,0.015261662,0.04674397],"study_design_scores_gemma":[0.0024880988,0.00032893388,0.91251904,0.000008219818,0.028979471,0.0000023464313,0.0008523699,0.008851755,0.0022175023,0.033130918,0.009846241,0.0007751217],"about_ca_topic_score_codex":0.00008905121,"about_ca_topic_score_gemma":0.00059711665,"teacher_disagreement_score":0.5632519,"about_ca_system_score_codex":0.000016663678,"about_ca_system_score_gemma":0.000091369206,"threshold_uncertainty_score":0.57950914},"labels":[],"label_agreement":null},{"id":"W4409300844","doi":"10.7150/thno.107061","title":"Modulation of brain immune microenvironment and cellular dynamics in systemic inflammation","year":2025,"lang":"en","type":"article","venue":"Theranostics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Inflammation; Immune system; Dynamics (music); Immune modulation; Neuroscience; Systemic inflammation; Chemistry; Cell biology; Biology; Immunology; Physics","score_opus":0.0066690815760260345,"score_gpt":0.20982659428374734,"score_spread":0.2031575127077213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409300844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99184626,0.00025080124,0.0069672926,0.00040579686,0.00006687299,0.00021796626,0.000003964001,0.000032364256,0.00020867787],"genre_scores_gemma":[0.9996223,0.0001006597,0.00006798158,0.00008019985,0.000005087941,0.0000033556469,0.000003492159,0.00001106045,0.00010585233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994388,0.00007132995,0.00020844875,0.0001216108,0.000075112875,0.00008465178],"domain_scores_gemma":[0.99962205,0.00017506609,0.00006251942,0.00012525852,0.000005340404,0.000009740889],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000092413,0.000065391796,0.000100682046,0.00008866052,0.000016621583,0.0000090114,0.000070740956,0.000043511147,0.0000021387127],"category_scores_gemma":[0.00014044427,0.00006591437,0.000015211822,0.0001351593,0.00006477631,0.00004054405,0.00002853169,0.00005251516,0.0000012991782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020732943,0.000021007856,0.0012360452,0.00006964285,0.0000016720694,0.0000010603355,0.00025372335,0.0011037022,0.9822892,0.010804175,0.0000029346963,0.0041961228],"study_design_scores_gemma":[0.00093287695,0.00003139185,0.02549549,0.0001545604,0.000004925646,0.0000017580883,0.00027165332,0.08409897,0.8845471,0.0042863493,0.00007419453,0.000100718134],"about_ca_topic_score_codex":0.000013725175,"about_ca_topic_score_gemma":0.000011041005,"teacher_disagreement_score":0.09774207,"about_ca_system_score_codex":0.00006296288,"about_ca_system_score_gemma":0.000010815649,"threshold_uncertainty_score":0.268791},"labels":[],"label_agreement":null},{"id":"W4409400041","doi":"10.30773/pi.2024.0152","title":"The Clinical Utility of Biomarkers in Diagnosing Major Depressive Disorder in Adults: A Systematic Review of Literature From 2013 to 2023","year":2025,"lang":"en","type":"review","venue":"Psychiatry Investigation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brain and Cognition Discovery Foundation; University of Toronto","funders":"Anhui University","keywords":"Medicine; Major depressive disorder; Clinical psychology; Psychiatry; Cognition","score_opus":0.03112893891621313,"score_gpt":0.34675292509844796,"score_spread":0.3156239861822348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409400041","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006035202,0.9921087,0.000010255699,0.0010853346,0.0009410934,0.0048483973,0.0003046393,0.000015587088,0.000082475075],"genre_scores_gemma":[0.0001344065,0.9980482,0.00026114623,0.0007313566,0.000037052832,0.0006630833,0.00008902492,0.000020825291,0.000014914317],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.99317116,0.0026614643,0.0028124256,0.000740535,0.0003659574,0.0002484619],"domain_scores_gemma":[0.9936289,0.0038806908,0.0014518574,0.00087107014,0.00007486818,0.00009258129],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011747879,0.00037303416,0.0019808316,0.00032837372,0.0000596479,0.000040033483,0.00077399786,0.00033363394,0.000012582514],"category_scores_gemma":[0.011978254,0.0002519886,0.0004633077,0.0027305656,0.00024728218,0.00012729956,0.0001303333,0.0005262092,0.000010674797],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020512534,0.00012528789,0.0016113019,0.9736211,0.000041834042,0.0000012600173,0.000124902,2.9810172e-7,8.0748e-7,0.00015328698,0.0023087473,0.021990715],"study_design_scores_gemma":[0.00038977768,0.000028786353,0.00081096205,0.99480534,0.00022018621,8.817781e-7,0.00006459406,0.000026515503,0.000004650632,0.0015824955,0.0018567413,0.0002090904],"about_ca_topic_score_codex":0.0002069868,"about_ca_topic_score_gemma":0.0009819035,"teacher_disagreement_score":0.021781625,"about_ca_system_score_codex":0.0000342221,"about_ca_system_score_gemma":0.00050175446,"threshold_uncertainty_score":0.99999326},"labels":[],"label_agreement":null},{"id":"W4409718590","doi":"10.1016/j.trecan.2025.03.008","title":"New insights into tryptophan metabolism in cancer","year":2025,"lang":"en","type":"review","venue":"Trends in cancer","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund; Foundation for the National Institutes of Health","keywords":"Tryptophan Metabolism; Tryptophan; Metabolism; Cancer; Computational biology; Biology; Chemistry; Biochemistry; Genetics; Amino acid","score_opus":0.072854153846123,"score_gpt":0.3950581419789259,"score_spread":0.32220398813280293,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409718590","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000041027637,0.98738617,0.000006006053,0.0002474355,0.0021529961,0.00039228788,0.000054348307,0.00008349472,0.009636263],"genre_scores_gemma":[0.00009879386,0.98223656,0.0000647729,0.0006854865,0.00040530675,0.0007693954,0.000016107537,0.000070299335,0.015653286],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964958,0.00033370542,0.00085316563,0.0012700581,0.00039855958,0.0006487443],"domain_scores_gemma":[0.9986224,0.00030374542,0.00028072196,0.00061677507,0.000014981787,0.00016137505],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000087201115,0.00071777106,0.0019913588,0.0014436916,0.000066822315,0.00007060177,0.0010393495,0.00047453502,0.0023144493],"category_scores_gemma":[0.00012002727,0.00059877255,0.00042687022,0.0047894954,0.00010606932,0.0002001516,0.00022355904,0.00091605424,0.00004592215],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011233074,0.00006880962,0.000003694526,0.0024908062,0.000015593132,0.000034030494,0.0004841724,0.00001429101,0.000013193116,0.0009162462,0.0057645994,0.99018335],"study_design_scores_gemma":[0.00081147323,0.000011727114,0.000085931446,0.008431408,0.000081716185,0.0000012841526,0.000010621751,0.0000059434265,0.00019363164,0.0006517948,0.9891267,0.00058776775],"about_ca_topic_score_codex":0.005914249,"about_ca_topic_score_gemma":0.026403608,"teacher_disagreement_score":0.9895956,"about_ca_system_score_codex":0.00063878426,"about_ca_system_score_gemma":0.0012543993,"threshold_uncertainty_score":0.99964637},"labels":[],"label_agreement":null},{"id":"W4410274505","doi":"10.1016/j.nbd.2025.106952","title":"Fatty acid binding proteins and their involvement in anxiety and mood disorders","year":2025,"lang":"en","type":"review","venue":"Neurobiology of Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Lawson Health Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Anxiety; Mood; Mood disorders; Psychology; Neuroscience; Computational biology; Biochemistry; Chemistry; Clinical psychology; Biology; Psychiatry","score_opus":0.026392711808033584,"score_gpt":0.27697558269643635,"score_spread":0.25058287088840275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410274505","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.040649097,0.955326,0.000010539203,0.000211242,0.00021497466,0.0025513656,0.00061387126,0.000061535466,0.00036134056],"genre_scores_gemma":[0.027525004,0.971971,0.000014481353,0.00018880349,0.000011606213,0.0001955087,0.000037264883,0.000023185032,0.000033155877],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99786204,0.00045754682,0.0004237552,0.0008577781,0.00006422122,0.0003346467],"domain_scores_gemma":[0.9989875,0.00031561733,0.00021192728,0.00033477283,0.000007710927,0.00014246412],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010150201,0.00041669694,0.00090998923,0.0003308924,0.00008298081,0.000019717461,0.00031202883,0.0001807222,0.0000111188165],"category_scores_gemma":[0.00037068,0.00031651094,0.00018561642,0.00039118514,0.0004833874,0.00006602467,0.00035652964,0.00032566936,0.0000023812845],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012414542,0.00074922846,0.00434062,0.045409717,0.000048171314,0.0000041670924,0.00023386399,0.0000011821135,0.0030552095,0.0009754932,0.00010001405,0.9449582],"study_design_scores_gemma":[0.013171348,0.0024428102,0.028190704,0.058643512,0.0014399056,0.000030008945,0.0007688916,0.000060022583,0.016120117,0.009784266,0.8621988,0.0071496046],"about_ca_topic_score_codex":0.000006150826,"about_ca_topic_score_gemma":0.00004592154,"teacher_disagreement_score":0.9378086,"about_ca_system_score_codex":0.00001811823,"about_ca_system_score_gemma":0.0001858297,"threshold_uncertainty_score":0.9999287},"labels":[],"label_agreement":null},{"id":"W4410398366","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_507_24","title":"Inflammatory markers and cognitive deficits in first-episode psychoses – A cross-sectional study","year":2025,"lang":"en","type":"article","venue":"Indian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Cross-sectional study; Psychology; Cognition; Medicine; Clinical psychology; Psychiatry; Pathology","score_opus":0.013220345055066784,"score_gpt":0.2933673529858324,"score_spread":0.2801470079307656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410398366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954282,0.00056559505,0.00002959827,0.0005665769,0.0017651862,0.00027380092,0.000010222253,0.000012759049,0.0013480656],"genre_scores_gemma":[0.99889237,0.000038215338,0.00009059147,0.0007707825,0.00010257167,0.00000791613,2.2919568e-7,0.000012017986,0.0000853163],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998459,0.0001591789,0.0005903754,0.00027308447,0.00027892293,0.00023944101],"domain_scores_gemma":[0.9991515,0.00031702186,0.0002688847,0.00010261888,0.000059994094,0.00009994906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041529918,0.00015788109,0.00020266493,0.0006296873,0.00017233992,0.00012345769,0.00024361866,0.00009016562,0.000055779656],"category_scores_gemma":[0.00043794382,0.00014825548,0.00009160223,0.0004925776,0.00018164588,0.0002738046,0.000038172235,0.000446871,0.000008954791],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053539587,0.0004478291,0.99659246,0.000043838372,0.00003088271,0.00009915205,0.0005729899,0.000018438712,0.00007860353,0.00032191337,0.00040000767,0.000858466],"study_design_scores_gemma":[0.003399777,0.00030200667,0.9905301,0.00020761952,0.0000099700865,0.00014638396,0.001770405,0.000004895977,0.00014994346,0.003198458,0.0001478353,0.00013260964],"about_ca_topic_score_codex":0.0000151511495,"about_ca_topic_score_gemma":0.0009794008,"teacher_disagreement_score":0.0060623875,"about_ca_system_score_codex":0.000031665073,"about_ca_system_score_gemma":0.00019070652,"threshold_uncertainty_score":0.6045683},"labels":[],"label_agreement":null},{"id":"W4410421293","doi":"10.1016/j.cpnec.2025.100302","title":"The systemic immune-inflammation index (SII) as a biomarker for depression in a community sample of adolescents","year":2025,"lang":"en","type":"article","venue":"Comprehensive Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health; Hospital for Sick Children","funders":"National Institute of Mental Health; National Institutes of Health; National Institute on Drug Abuse; Garry Hurvitz Centre for Brain and Mental Health; Hospital for Sick Children","keywords":"Depression (economics); Systemic inflammation; Biomarker; Inflammation; Sample (material); Index (typography); Immune system; Psychology; Medicine; Immunology; Clinical psychology; Biology; Computer science; Economics; Chemistry","score_opus":0.035320510358672695,"score_gpt":0.32671793747407546,"score_spread":0.2913974271154028,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410421293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99344426,0.0006985997,0.0020452235,0.00075285777,0.0011587817,0.0012197596,0.000016468515,0.00006773177,0.00059630076],"genre_scores_gemma":[0.9987441,0.0003327165,0.000034952376,0.0006262558,0.0000115434,0.00016671242,0.000004636241,0.000017164324,0.00006192347],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99739105,0.0010876395,0.0005708217,0.00036050368,0.00014189958,0.00044806965],"domain_scores_gemma":[0.99632514,0.002545407,0.00024287797,0.00072313054,0.00012929592,0.000034157456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007702915,0.00020288459,0.0003230329,0.00030115922,0.00038423002,0.000027979413,0.0007486163,0.00006258403,0.000005060248],"category_scores_gemma":[0.0013475006,0.00016713495,0.00012390199,0.0005152256,0.00036133654,0.00007362356,0.00025387513,0.00038910002,0.000010582247],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019407413,0.00027194657,0.029329885,0.0004194468,0.000020878984,0.000010782292,0.00026052832,0.000041175917,0.9426548,0.004213662,0.0006759863,0.020160176],"study_design_scores_gemma":[0.008486563,0.00027969666,0.72191685,0.00079904584,0.00001880186,0.00015475258,0.0016053643,0.0019124626,0.23184088,0.023804896,0.008822545,0.00035815215],"about_ca_topic_score_codex":0.00016451384,"about_ca_topic_score_gemma":0.00007447328,"teacher_disagreement_score":0.71081394,"about_ca_system_score_codex":0.00003478845,"about_ca_system_score_gemma":0.000049473758,"threshold_uncertainty_score":0.6815565},"labels":[],"label_agreement":null},{"id":"W4410513358","doi":"10.1007/978-3-031-85519-1_19","title":"Biomarkers of Neuroprogression","year":2025,"lang":"en","type":"book-chapter","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"History","score_opus":0.024878663146055156,"score_gpt":0.26056666490681235,"score_spread":0.2356880017607572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410513358","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000082458915,0.00014146122,0.000029836194,0.00019809086,0.00029812552,0.00017687357,0.000020927857,0.00008837701,0.99896383],"genre_scores_gemma":[0.007909706,0.00023729139,0.00011159043,0.00078669185,0.000019219775,0.0000019199704,0.0000033571014,0.000023438208,0.9909068],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990611,0.000014388581,0.00021262359,0.00036581742,0.00022343168,0.0001226025],"domain_scores_gemma":[0.99937075,0.0001379167,0.00012340987,0.00030945012,0.000019282208,0.000039180093],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000031046508,0.00018062149,0.00020198738,0.00018577372,0.00003448069,0.000011617326,0.00027435055,0.00015351547,0.0014818471],"category_scores_gemma":[0.000106490756,0.00014583861,0.0001391558,0.000049255916,0.00018867636,0.000029464367,0.00012655472,0.00013573364,0.000087728986],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007154605,0.00004320711,0.0000059579365,0.00018839477,0.00002014747,0.000043981316,0.000016466529,3.5336024e-7,0.061836265,0.7308926,0.07592467,0.1309564],"study_design_scores_gemma":[0.0004560805,0.000111513065,0.00003668479,0.0004132508,0.000020041807,0.0000061786404,0.0000061968094,0.00004055226,0.18817155,0.021655701,0.7886941,0.00038814146],"about_ca_topic_score_codex":0.0000023186963,"about_ca_topic_score_gemma":0.0000014061353,"teacher_disagreement_score":0.71276945,"about_ca_system_score_codex":0.000008099202,"about_ca_system_score_gemma":0.00005383625,"threshold_uncertainty_score":0.99943095},"labels":[],"label_agreement":null},{"id":"W4410524579","doi":"10.1016/j.bbih.2025.101015","title":"The effect of dual inflammation on the acute phase clinical outcomes of schizophrenia patients with comorbid COVID-19","year":2025,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Beijing Municipal Science and Technology Commission; National Natural Science Foundation of China","keywords":"Coronavirus disease 2019 (COVID-19); Schizophrenia (object-oriented programming); Inflammation; Medicine; Dual (grammatical number); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Comorbidity; Intensive care medicine; Internal medicine; Psychiatry; Virology; Disease","score_opus":0.04206597055810242,"score_gpt":0.40185625828927696,"score_spread":0.35979028773117455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410524579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98914737,0.000019407711,0.000033902623,0.008500131,0.00025175296,0.0017925865,0.00013212646,0.00005012411,0.00007258191],"genre_scores_gemma":[0.99665636,0.00004019035,0.000020369498,0.0030551988,0.000009600439,0.00007887989,0.000028701437,0.000015230144,0.00009547726],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9954578,0.002722501,0.0007739714,0.0002629555,0.00047073897,0.0003120191],"domain_scores_gemma":[0.9901804,0.00819775,0.00057200104,0.00086775556,0.00005591927,0.00012622372],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020557544,0.00021625597,0.0004518709,0.00011826364,0.0007804572,0.00003605673,0.0006010132,0.00008413833,0.000019108902],"category_scores_gemma":[0.0040756837,0.00011330974,0.00016435476,0.00050515623,0.0007564924,0.00008579831,0.00013989153,0.00054176897,0.00000586828],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016136365,0.0050128675,0.69952226,0.0004354138,0.00020567313,0.000014327364,0.0021966468,0.00002426132,0.010146422,0.01480323,0.0072286306,0.2442739],"study_design_scores_gemma":[0.012751953,0.004931993,0.9657823,0.00008128075,0.00006365631,0.0000015427402,0.000171375,0.000016940212,0.014466511,0.0000962936,0.0014704178,0.00016575212],"about_ca_topic_score_codex":0.00031779116,"about_ca_topic_score_gemma":0.0001559447,"teacher_disagreement_score":0.26626003,"about_ca_system_score_codex":0.0000801931,"about_ca_system_score_gemma":0.0005014184,"threshold_uncertainty_score":0.6002725},"labels":[],"label_agreement":null},{"id":"W4410718292","doi":"10.62019/dfr1yz07","title":"NEURO-INFLAMMATION AND ITS IMPACT ON NEURODEGENERATIVE DISEASES: A SYSTEMATIC REVIEW","year":2025,"lang":"en","type":"review","venue":"Journal of medical & health sciences review.","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Inflammation; Neuroscience; Medicine; Psychology; Immunology","score_opus":0.057234547128496474,"score_gpt":0.4555261144549911,"score_spread":0.3982915673264946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410718292","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000002180093,0.9808958,0.000016245709,0.014617794,0.00061885116,0.0036873913,0.000034943878,0.000018834611,0.00010792999],"genre_scores_gemma":[0.0000042881484,0.97174835,0.000010108544,0.027886592,0.00021007207,0.000075733515,0.0000026649448,0.000017642386,0.000044564764],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.98710734,0.0047124173,0.003537725,0.0006765614,0.0034236156,0.0005423165],"domain_scores_gemma":[0.9896148,0.00430558,0.004466232,0.00037993156,0.00014158312,0.0010918996],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.007110877,0.00058018486,0.0054155593,0.00048101813,0.00034476846,0.00011787555,0.0017798536,0.00015123127,0.00015439113],"category_scores_gemma":[0.045760192,0.0002939398,0.0010329497,0.0021679178,0.00028683493,0.00031378437,0.00017014644,0.001130459,0.000042444703],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000017785773,0.00004330031,7.4440955e-8,0.8397906,0.000011441771,0.000048753383,0.000008532616,3.323636e-7,1.1961038e-7,0.00033919836,0.010785569,0.1489703],"study_design_scores_gemma":[0.0001336704,0.00056918355,7.506881e-7,0.8972191,0.0005209584,0.0005721618,0.0000029483506,0.000048713846,5.721907e-7,0.000032752258,0.10070933,0.00018984081],"about_ca_topic_score_codex":0.0000016037518,"about_ca_topic_score_gemma":7.417548e-7,"teacher_disagreement_score":0.14878047,"about_ca_system_score_codex":0.0001718132,"about_ca_system_score_gemma":0.0056485897,"threshold_uncertainty_score":0.99998844},"labels":[],"label_agreement":null},{"id":"W4410756383","doi":"10.1051/medsci/2025063","title":"Les premiers succès de la piste immuno-métabolique en psychiatrie de précision","year":2025,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Agence Nationale de la Recherche","keywords":"Gynecology; Medicine","score_opus":0.030368744489087548,"score_gpt":0.37125091134112215,"score_spread":0.3408821668520346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410756383","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005953831,0.8989389,0.0016231692,0.0018130403,0.0027152274,0.0013888436,0.00012351995,0.0002175798,0.08722588],"genre_scores_gemma":[0.0068443827,0.9709179,0.0047978847,0.0013100615,0.0004687462,0.0001559843,0.000009792089,0.00007141066,0.015423829],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.990206,0.003891335,0.0012281098,0.0019422453,0.0010366117,0.0016956759],"domain_scores_gemma":[0.9914449,0.006666946,0.0006738739,0.0008075911,0.00006958815,0.00033710667],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":["sts"],"category_scores_codex":[0.0047196844,0.0010352938,0.0015181843,0.0008461987,0.0017976545,0.0007648652,0.0037414697,0.0009801713,0.0006196488],"category_scores_gemma":[0.005237482,0.00087520044,0.0008496786,0.003662874,0.0037530877,0.0004320346,0.0005550066,0.0013449996,0.00019102519],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071655326,0.0010918094,0.003906631,0.011723202,0.00006741545,0.000102856706,0.0010216992,0.0003157554,0.0022193522,0.097919405,0.018309409,0.8632508],"study_design_scores_gemma":[0.00094569236,0.0004141046,0.0028565424,0.010431489,0.00020605601,0.00028088898,0.00034584245,0.00020293657,0.0009146658,0.007837964,0.97447544,0.0010883748],"about_ca_topic_score_codex":0.00066915486,"about_ca_topic_score_gemma":0.000083594314,"teacher_disagreement_score":0.956166,"about_ca_system_score_codex":0.0005437247,"about_ca_system_score_gemma":0.004819622,"threshold_uncertainty_score":0.9995019},"labels":[],"label_agreement":null},{"id":"W4410817651","doi":"10.1016/j.jad.2025.119545","title":"Inflammatory biomarkers as predictors for unlocking antidepressant efficacy: Assessing predictive value and risk stratification in major depressive disorder in a prospective longitudinal study","year":2025,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Qatar National Library; Hamad Medical Corporation; Medical Research Center, Hamad Medical Corporation","keywords":"Major depressive disorder; Internal medicine; Biomarker; Prospective cohort study; Medicine; Antidepressant; Depression (economics); Neutrophil to lymphocyte ratio; Mean corpuscular volume; Oncology; Lymphocyte; Hematocrit","score_opus":0.011160962832903161,"score_gpt":0.29898310385525045,"score_spread":0.28782214102234727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410817651","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890234,0.0005708339,0.006290675,0.00011875517,0.0002908659,0.0032102403,0.0000180646,0.000031660285,0.00044554126],"genre_scores_gemma":[0.99938124,0.0002374608,0.00010997654,0.000025191319,0.000029397575,0.00017437457,0.0000014572997,0.00003314014,0.000007784399],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99674255,0.0008558457,0.000789031,0.0007349039,0.00043967893,0.00043799932],"domain_scores_gemma":[0.9964057,0.0023319896,0.00078246125,0.00022295273,0.00016372434,0.00009317901],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009907329,0.00036581676,0.00056093105,0.0011331617,0.00030244826,0.00017948191,0.00032233066,0.00014269116,0.000003667326],"category_scores_gemma":[0.0051602586,0.0003314399,0.00015373495,0.0012107273,0.00033225786,0.0009618046,0.000102174105,0.0006312259,4.1630284e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014306726,0.0015548967,0.9758974,0.00006976758,0.00022643789,0.000027837861,0.00366118,0.0031854818,0.0034036539,0.00046874594,0.000016243706,0.010057718],"study_design_scores_gemma":[0.0116304,0.00090750784,0.96282315,0.0003533075,0.000126908,0.000008350653,0.011068206,0.002376667,0.004186744,0.00623903,0.0000073636193,0.00027234916],"about_ca_topic_score_codex":0.00035275053,"about_ca_topic_score_gemma":0.0019380924,"teacher_disagreement_score":0.013074199,"about_ca_system_score_codex":0.00026103837,"about_ca_system_score_gemma":0.00033780804,"threshold_uncertainty_score":0.99991375},"labels":[],"label_agreement":null},{"id":"W4410886528","doi":"10.1126/sciadv.adt7176","title":"Proteomic signatures of corona and herpes viral antibodies identify IGDCC4 as a mediator of neurodegeneration","year":2025,"lang":"en","type":"article","venue":"Science Advances","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Institute on Aging","keywords":"Neurodegeneration; Neurocognitive; Dementia; Immunology; Disease; Medicine; Biology; Cognition; Bioinformatics; Neuroscience; Internal medicine","score_opus":0.00979184828046612,"score_gpt":0.30429904374447775,"score_spread":0.2945071954640116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410886528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99714226,0.0012935575,0.00008881794,0.00020743102,0.00032208255,0.00022411573,0.000008417531,0.00002206056,0.00069128786],"genre_scores_gemma":[0.99902177,0.00027200347,0.00035674585,0.00019854157,0.000011559192,0.000008510071,3.9049561e-7,0.0000030768692,0.00012737949],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888945,0.00004215894,0.00019417133,0.00035805214,0.00034267418,0.00017352494],"domain_scores_gemma":[0.99953556,0.000097682794,0.00012998024,0.00014563154,0.00005848188,0.000032660224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018044566,0.000091066475,0.00014340147,0.00019437875,0.00016306249,0.00004213529,0.00033896562,0.000025486943,0.0000066123735],"category_scores_gemma":[0.0009517191,0.00007438684,0.000026512902,0.00060981466,0.0017002423,0.0007857924,0.000095867894,0.00005140583,0.0000018620937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023200906,0.00003116349,0.0011999495,0.000050133567,7.405051e-7,7.086496e-7,0.00015660837,0.00007592175,0.98271364,0.004995853,0.000018968443,0.010733085],"study_design_scores_gemma":[0.00019464178,0.00007839045,0.02209491,0.00003699235,0.0000026207447,8.735341e-7,0.00013362661,0.00013064289,0.97094715,0.0060960394,0.00021764816,0.00006645994],"about_ca_topic_score_codex":0.000010608984,"about_ca_topic_score_gemma":0.000011949015,"teacher_disagreement_score":0.02089496,"about_ca_system_score_codex":0.000007578543,"about_ca_system_score_gemma":0.00014632162,"threshold_uncertainty_score":0.6264614},"labels":[],"label_agreement":null},{"id":"W4410953371","doi":"10.3390/mps8030056","title":"Towards Automated Testing of Kynurenine for Point-of-Care Metabolomics","year":2025,"lang":"en","type":"article","venue":"Methods and Protocols","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Genome Alberta","keywords":"Point-of-care testing; Metabolomics; Kynurenine; Point of care; Computational biology; Computer science; Data science; Chemistry; Medicine; Biology; Chromatography; Biochemistry; Immunology; Pathology; Tryptophan","score_opus":0.08415713303900986,"score_gpt":0.45149174905351097,"score_spread":0.3673346160145011,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410953371","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0633091,0.00075630256,0.5814794,0.0011487089,0.00045974422,0.32091808,0.0003467737,0.0010116601,0.030570254],"genre_scores_gemma":[0.016299803,0.0000030627652,0.95210505,0.00022503684,0.000014566088,0.031201262,0.0000013745727,0.000013697648,0.0001361392],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990132,0.00024393857,0.0002906197,0.00023442632,0.00007181285,0.00014599325],"domain_scores_gemma":[0.99866724,0.0008956845,0.0001410817,0.00017212947,0.00009640345,0.000027453854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005750709,0.000104882936,0.00030548268,0.0000937551,0.00006193717,0.000018665622,0.00015960752,0.00006286925,0.000009160557],"category_scores_gemma":[0.003558162,0.00008528669,0.000065720335,0.0004107954,0.000109867644,0.000052122312,0.0000687655,0.0000600736,1.3500977e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013277492,0.00003730823,0.00021932543,0.00082150614,0.0000067162155,2.2601728e-7,0.00020775004,0.00000552903,0.6748061,0.010775261,0.00010272309,0.31288478],"study_design_scores_gemma":[0.00098306,0.0002506714,0.0013511901,0.00015145724,0.000011481861,9.2738725e-7,0.00009360862,0.0034141166,0.974731,0.008796263,0.010132209,0.00008400689],"about_ca_topic_score_codex":0.000007512197,"about_ca_topic_score_gemma":6.721788e-7,"teacher_disagreement_score":0.37062567,"about_ca_system_score_codex":0.000005337183,"about_ca_system_score_gemma":0.000082118226,"threshold_uncertainty_score":0.4259709},"labels":[],"label_agreement":null},{"id":"W4410957788","doi":"10.1177/13872877251346981","title":"Glutathione peroxidase activity in Alzheimer's disease patients: A systematic review and meta-analysis","year":2025,"lang":"en","type":"review","venue":"Journal of Alzheimer s Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Glutathione peroxidase; Oxidative stress; Meta-analysis; Alzheimer's disease; Medicine; Internal medicine; Disease; Bioinformatics; Biology; Superoxide dismutase","score_opus":0.08266553036509477,"score_gpt":0.34822612940395303,"score_spread":0.26556059903885826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410957788","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000021655496,0.99556786,0.000009486058,0.00044392343,0.0001058588,0.0032003596,0.0005956264,0.000022907769,0.000032298056],"genre_scores_gemma":[0.0026737836,0.9956065,0.00001995346,0.0012574131,0.00002661763,0.0002907457,0.0000199357,0.000052934538,0.000052112806],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.992484,0.002697651,0.0024050896,0.0008774092,0.0010560268,0.00047983578],"domain_scores_gemma":[0.9938772,0.0008849701,0.002853496,0.0010143109,0.00021556333,0.0011544904],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00087747583,0.0009386606,0.009079119,0.0014542158,0.00013285344,0.00017008213,0.000870742,0.00014510004,0.00023535467],"category_scores_gemma":[0.002871721,0.0006166956,0.006224326,0.0025164443,0.00017838892,0.00060445163,0.00026045952,0.0007520248,0.00002718899],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012445732,0.00228495,0.00001021607,0.8156286,0.17095274,0.00081329746,0.00004621183,0.000007381654,3.1868464e-7,0.00008371457,0.00067599124,0.009372112],"study_design_scores_gemma":[0.00038264296,0.00004310205,0.000067250185,0.039724413,0.95749086,0.000009157704,0.000004804683,0.000006158475,0.0000012457549,0.000053797394,0.0016789153,0.00053767016],"about_ca_topic_score_codex":0.000005144387,"about_ca_topic_score_gemma":0.0000020927102,"teacher_disagreement_score":0.7865381,"about_ca_system_score_codex":0.00007227486,"about_ca_system_score_gemma":0.0009051592,"threshold_uncertainty_score":0.9996284},"labels":[],"label_agreement":null},{"id":"W4411370183","doi":"10.1016/j.bbi.2025.06.007","title":"Corrigendum to “Early-life gut inflammation drives sex-dependent shifts in the microbiome-endocrine-brain axis” [Brain Behav. Immun. 125 (2025) 117–139]","year":2025,"lang":"en","type":"erratum","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health; Canadian Institute for Advanced Research; University of British Columbia","funders":"","keywords":"Microbiome; Inflammation; Endocrine system; Gut microbiome; Medicine; Neuroscience; Psychology; Biology; Immunology; Bioinformatics; Internal medicine; Hormone","score_opus":0.029589965832068132,"score_gpt":0.2907439891058675,"score_spread":0.2611540232737994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411370183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94749844,0.0012441596,0.00005701129,0.021227362,0.014587479,0.00496236,0.0012731714,0.00038562535,0.008764408],"genre_scores_gemma":[0.49998257,0.00067672366,0.00009075135,0.018269312,0.0006834752,0.00150496,0.0011144774,0.00025924164,0.47741848],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.99218893,0.0024258846,0.0013901966,0.001565743,0.0010046444,0.0014245805],"domain_scores_gemma":[0.9956499,0.0011430676,0.0006232712,0.0021114466,0.00012597651,0.00034636536],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0014461523,0.0012356095,0.0011782738,0.0013694181,0.0011018508,0.0008615609,0.0027903956,0.0008548708,0.00030868562],"category_scores_gemma":[0.0033530488,0.0011056722,0.0004075409,0.0015751085,0.00060754834,0.00054749934,0.001306005,0.0034271076,0.00013537443],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015819006,0.0008440994,0.0017032658,0.00024380113,0.00003098768,0.00023540828,0.006748069,0.0000022292732,0.28467327,0.00044361484,0.6935819,0.011335196],"study_design_scores_gemma":[0.003908743,0.0006437512,0.5141598,0.0008051837,0.00016317803,0.00008041322,0.0072795195,0.000017730219,0.0160628,0.0003615842,0.4539933,0.002524007],"about_ca_topic_score_codex":0.0022742914,"about_ca_topic_score_gemma":0.0015583767,"teacher_disagreement_score":0.51245654,"about_ca_system_score_codex":0.00025143838,"about_ca_system_score_gemma":0.0006275651,"threshold_uncertainty_score":0.99913937},"labels":[],"label_agreement":null},{"id":"W4411521903","doi":"10.1101/2025.06.18.660280","title":"Brain Region-Specific Gene Co-expression Networks Reveal Neuroinflammation and ER Stress Signatures in Major Depressive Disorder","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Neuroinflammation; Transcriptome; Major depressive disorder; Gene; Gene expression; Gene co-expression network; Computational biology; Neuroscience; Biology; Gene expression profiling; Bioinformatics; Psychology; Genetics; Inflammation; Immunology; Amygdala; Gene ontology","score_opus":0.012923688495782511,"score_gpt":0.22775154192727468,"score_spread":0.21482785343149216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411521903","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98807853,0.0041094287,0.0036217493,0.00088422076,0.0009819928,0.0016500261,0.00025134368,0.00038333933,0.000039378527],"genre_scores_gemma":[0.996506,0.0015265677,0.00044969586,0.0008157052,0.00031098968,0.00024750503,0.0000014104985,0.000099963865,0.000042169966],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956888,0.0006003232,0.00068559265,0.0018500434,0.00046308624,0.00071217987],"domain_scores_gemma":[0.9974024,0.0005309388,0.0005147067,0.0011980756,0.00013149357,0.00022235735],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002806439,0.0007204572,0.00061658304,0.0005420726,0.00031054844,0.00036806014,0.00078458403,0.0008222719,0.000025815672],"category_scores_gemma":[0.00058852276,0.00074790814,0.00013244968,0.0007130388,0.00026256163,0.0003695714,0.00072445354,0.0014527051,0.0000066924686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018837294,0.00020789659,0.009043199,0.00041396508,0.000018561726,0.00025487397,0.00004025937,0.006989288,0.9779699,0.00085262995,0.00399472,0.000026367157],"study_design_scores_gemma":[0.002241059,0.000040256407,0.16946396,0.0013689346,0.000025579993,6.6461226e-8,0.000008047902,0.003718737,0.8174402,0.000024254548,0.004427766,0.0012411457],"about_ca_topic_score_codex":0.000029161181,"about_ca_topic_score_gemma":0.000009322935,"teacher_disagreement_score":0.16052969,"about_ca_system_score_codex":0.00013696635,"about_ca_system_score_gemma":0.00020453366,"threshold_uncertainty_score":0.9994972},"labels":[],"label_agreement":null},{"id":"W4411568112","doi":"10.1007/s00115-025-01839-1","title":"Genetisch informierte Therapie in der Psychiatrie: neue Dynamik durch APOE und Antikörpertherapie der Alzheimer-Krankheit","year":2025,"lang":"de","type":"review","venue":"Der Nervenarzt","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Shores Centre for Mental Health Sciences","funders":"","keywords":"Philosophy; Medicine","score_opus":0.04100453093919485,"score_gpt":0.3462207656796137,"score_spread":0.3052162347404188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411568112","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015059409,0.9827741,0.00030066338,0.0026169969,0.004238612,0.0040451703,0.00034782084,0.0002793876,0.0038913311],"genre_scores_gemma":[0.0072406894,0.97831374,0.00044799788,0.007897872,0.0006697526,0.0005675096,0.00037935513,0.0004277549,0.004055298],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9879706,0.0015422585,0.0031326492,0.0031734488,0.0014862219,0.0026948275],"domain_scores_gemma":[0.9940129,0.0012914513,0.0011530165,0.0027394865,0.00020332882,0.0005998433],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.0009536726,0.0025629054,0.0035432687,0.0017945374,0.0007796439,0.0007865165,0.0034147515,0.0018242605,0.0016467475],"category_scores_gemma":[0.00037339874,0.002288115,0.0020966453,0.0051159444,0.0007787661,0.0007288364,0.0006971577,0.0027218019,0.0019251499],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025825598,0.001708613,0.0010031136,0.010453578,0.003851398,0.0004808476,0.0010281821,0.00023889852,0.00014607258,0.0015886525,0.013811691,0.9654307],"study_design_scores_gemma":[0.0041248165,0.0003444343,0.0015961394,0.006349828,0.0025732818,0.00010601287,0.0000751075,0.00064772594,0.00016709033,0.0007132915,0.98045754,0.0028447432],"about_ca_topic_score_codex":0.00045105274,"about_ca_topic_score_gemma":0.0010395393,"teacher_disagreement_score":0.96664584,"about_ca_system_score_codex":0.00022730543,"about_ca_system_score_gemma":0.0022651183,"threshold_uncertainty_score":0.99957895},"labels":[],"label_agreement":null},{"id":"W4411659181","doi":"10.7150/thno.113573","title":"Tea plant-inspired nanoassembled supraparticles alleviate colitis and associated mental disorders via microbiota-gut-brain interactions","year":2025,"lang":"en","type":"article","venue":"Theranostics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Gut flora; Colitis; Gut–brain axis; Medicine; Biology; Immunology","score_opus":0.01384286295351268,"score_gpt":0.25779560124332734,"score_spread":0.24395273828981467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411659181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990558,0.00012044021,0.00027820742,0.0054425276,0.0005756243,0.000482814,0.00017848857,0.0005012709,0.0018626131],"genre_scores_gemma":[0.9954214,0.00038236825,0.000053249933,0.002914884,0.000016952989,0.00002018635,0.000024788807,0.00004669848,0.001119489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854296,0.00022978541,0.00028543413,0.00038577174,0.00014335877,0.00041270297],"domain_scores_gemma":[0.9987269,0.00086730235,0.000092951894,0.00020633335,0.000022393935,0.000084113686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011333327,0.00022661763,0.00023365255,0.00013009769,0.00025322707,0.00011043725,0.00021309475,0.00008778351,0.00004101568],"category_scores_gemma":[0.00055416994,0.00022144549,0.000073457064,0.00035773925,0.00020468091,0.00014592566,0.00009536935,0.00018108281,0.000016668846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014137424,0.00029931942,0.0010662461,0.000018401943,0.000052692685,0.000006797391,0.0007583574,0.000006610582,0.9845549,0.003255246,0.007065895,0.0027741606],"study_design_scores_gemma":[0.009655719,0.000441411,0.07265601,0.00035362825,0.00011589946,0.000049682258,0.0014298864,0.0068896217,0.77680516,0.009911919,0.12039431,0.001296763],"about_ca_topic_score_codex":0.00007185817,"about_ca_topic_score_gemma":0.0004931229,"teacher_disagreement_score":0.20774975,"about_ca_system_score_codex":0.000072869385,"about_ca_system_score_gemma":0.000047950572,"threshold_uncertainty_score":0.9030285},"labels":[],"label_agreement":null},{"id":"W4411866410","doi":"10.1371/journal.pone.0327188","title":"Microsporidia infection alters C. elegans lipid levels","year":2025,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Institute of Infection and Immunity","keywords":"Microsporidia; Biology; Caenorhabditis elegans; Lipid metabolism; Lipid droplet; Obligate; Intracellular parasite; Caenorhabditis; Gene; Host (biology); Cell biology; Genetics; Microbiology; Biochemistry; Spore; Ecology","score_opus":0.05533360857339343,"score_gpt":0.2582327750259824,"score_spread":0.20289916645258899,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411866410","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98711777,0.000027617614,0.00020230334,0.0010574473,0.00022534769,0.00019460615,0.000011257791,0.00017891637,0.010984742],"genre_scores_gemma":[0.991456,0.00006443767,0.00016577392,0.002944924,0.000074657844,0.000016812874,0.0000016085222,0.000010951395,0.005264834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917877,0.000041243726,0.00013027995,0.00027945955,0.00015509236,0.00021512799],"domain_scores_gemma":[0.99961126,0.00009024713,0.000036008405,0.00019999524,0.000020662179,0.000041805913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053793017,0.00009851917,0.0001276342,0.00011115092,0.00011079637,0.000048102615,0.00013162364,0.000051169132,0.00012464111],"category_scores_gemma":[0.00027787237,0.000101387646,0.000044672597,0.00039964943,0.000068716974,0.00013117507,0.00004177828,0.00012850158,0.00022150393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013235014,0.00053225545,0.002278024,0.00005029545,0.000013504705,0.0000016934869,0.00009476457,0.000002895079,0.9933666,0.0012777302,0.0012334579,0.001135566],"study_design_scores_gemma":[0.0003457003,0.00003401092,0.013537456,0.00006283082,0.000013785754,5.094631e-7,0.00000974835,0.00007530462,0.98246324,0.0005345994,0.0028155388,0.00010728282],"about_ca_topic_score_codex":0.000034879533,"about_ca_topic_score_gemma":0.000018155662,"teacher_disagreement_score":0.011259433,"about_ca_system_score_codex":0.000034576908,"about_ca_system_score_gemma":0.00004093202,"threshold_uncertainty_score":0.41344684},"labels":[],"label_agreement":null},{"id":"W4411875933","doi":"10.1152/physiol.2025.40.s1.0722","title":"The impact of chronic risperidone treatment on the metabolic health of adolescent mice","year":2025,"lang":"en","type":"article","venue":"Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Risperidone; Medicine; Internal medicine; Physiology; Pharmacology; Biology; Endocrinology; Psychiatry; Schizophrenia (object-oriented programming)","score_opus":0.02841212199618882,"score_gpt":0.33068513890459084,"score_spread":0.302273016908402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411875933","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944317,0.002116997,0.000006552675,0.0024641461,0.00013209505,0.00028631074,0.000016999717,0.00001059108,0.0005346499],"genre_scores_gemma":[0.99662673,0.0025890914,0.0000012456711,0.0006238759,0.000025799327,0.00001701306,7.1336797e-7,0.000004368778,0.00011117948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991287,0.00027423864,0.0001632701,0.00016734561,0.0000568254,0.0002096448],"domain_scores_gemma":[0.99909604,0.000431933,0.000121061916,0.0003194163,0.000011871907,0.000019654592],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006878938,0.00009645214,0.0002147376,0.00003186737,0.00011660237,0.0000033428796,0.0002419797,0.000020451826,0.00002336453],"category_scores_gemma":[0.00008648931,0.00004190237,0.0001422883,0.00019964966,0.000269493,0.000010595503,0.000038134032,0.0000691551,0.000010545018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016422608,0.00041338906,0.00003597125,0.000014363815,0.000033491076,1.0136829e-7,0.00014200804,0.00025181953,0.96611077,0.016295034,0.0014125501,0.015126267],"study_design_scores_gemma":[0.0009229941,0.0014032999,0.15101174,0.0000319309,0.0000072704443,7.0363427e-7,0.000096598975,0.0005139773,0.83815986,0.0024599447,0.005319064,0.00007265162],"about_ca_topic_score_codex":0.00028844952,"about_ca_topic_score_gemma":0.000032368687,"teacher_disagreement_score":0.15097576,"about_ca_system_score_codex":0.00007392782,"about_ca_system_score_gemma":0.0002048353,"threshold_uncertainty_score":0.17087291},"labels":[],"label_agreement":null},{"id":"W4411951390","doi":"10.37275/scipsy.v6i2.192","title":"Neutrophil to-lymphocyte (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratios (PLR) as biomarkers for suicidal behavior in children and adolescents with depression or anxiety: A systematic review and meta-analysis","year":2025,"lang":"en","type":"review","venue":"Scientia Psychiatrica","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Lymphocyte; Monocyte; Anxiety; Depression (economics); Immunology; Platelet; Medicine; Psychology; Clinical psychology; Psychiatry","score_opus":0.027831297616495086,"score_gpt":0.3203868820336685,"score_spread":0.2925555844171734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411951390","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0020662714,0.9729206,0.00044151003,0.0002920326,0.00024301825,0.023148606,0.00073760067,0.00011958938,0.000030793755],"genre_scores_gemma":[0.0035848212,0.9844013,0.001809404,0.0039087855,0.000049581075,0.00523117,0.00008702934,0.00016083225,0.0007670765],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99110025,0.00092287397,0.0020831719,0.0036687609,0.0010420069,0.0011829232],"domain_scores_gemma":[0.99587363,0.0003697931,0.0010140196,0.0015943816,0.00015135377,0.0009968034],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0011197923,0.0015316362,0.006358088,0.003320842,0.0006843334,0.0008023218,0.001280735,0.00038286237,0.000036183235],"category_scores_gemma":[0.0006946861,0.00103051,0.0011649526,0.009580257,0.00023962004,0.00037723596,0.00069116696,0.00031068377,0.000037617396],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029240903,0.0014622435,0.0011552362,0.89095837,0.021762053,0.000119244745,0.0005962279,0.00011329192,0.00015320836,0.00011555639,0.0030842503,0.0775562],"study_design_scores_gemma":[0.014289691,0.0021802403,0.0025515978,0.07295425,0.8727567,0.0012779186,0.0001213231,0.0003102786,0.00036633195,0.000037401882,0.025872879,0.007281372],"about_ca_topic_score_codex":0.00021058063,"about_ca_topic_score_gemma":0.00033551207,"teacher_disagreement_score":0.85099465,"about_ca_system_score_codex":0.00036289092,"about_ca_system_score_gemma":0.0012678405,"threshold_uncertainty_score":0.9997432},"labels":[],"label_agreement":null},{"id":"W4412047490","doi":"10.31363/2313-7053-2025-3-1083","title":"Association of hematological coefficients with markers of inflammation and oxidative stress in schizophrenia: results of a pilot analysis","year":2025,"lang":"en","type":"article","venue":"V M BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Oxidative stress; Association (psychology); Inflammation; Schizophrenia (object-oriented programming); Medicine; Immunology; Internal medicine; Clinical psychology; Psychiatry; Psychology; Psychotherapist","score_opus":0.014219289672928914,"score_gpt":0.3160267165378696,"score_spread":0.3018074268649407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412047490","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857948,0.006951377,0.00042743012,0.0048857713,0.00011145625,0.0003672717,0.000062740284,0.0000057452967,0.0013934372],"genre_scores_gemma":[0.98177934,0.017297206,0.00046471515,0.00041425417,0.000006241848,0.000008398051,0.000011281636,0.0000029989415,0.000015583204],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99788064,0.00044225127,0.000917731,0.00031671027,0.00031366217,0.00012902821],"domain_scores_gemma":[0.9984844,0.0004615624,0.0007351192,0.00019879587,0.00006675522,0.0000534069],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008362418,0.00011295215,0.00072447176,0.0002974571,0.000015430674,0.0000016226672,0.00016590091,0.0001248029,0.00004088616],"category_scores_gemma":[0.0016776505,0.00008216993,0.00007034808,0.0012191974,0.00039893814,0.000040562838,0.00004187243,0.00015979605,2.047438e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018910145,0.007973849,0.71381176,0.058081742,0.0017767416,0.000015677662,0.00069027726,0.000016510347,0.028190535,0.041401055,0.0044706934,0.124661036],"study_design_scores_gemma":[0.026766332,0.0056384807,0.89969873,0.038226422,0.0014459002,0.000022751317,0.0004155913,0.0003205527,0.021356061,0.0047072633,0.0008607584,0.000541161],"about_ca_topic_score_codex":0.000014115541,"about_ca_topic_score_gemma":0.000118938595,"teacher_disagreement_score":0.18588698,"about_ca_system_score_codex":0.0000063193606,"about_ca_system_score_gemma":0.00007031132,"threshold_uncertainty_score":0.33507925},"labels":[],"label_agreement":null},{"id":"W4412048110","doi":"10.1038/s41398-025-03449-6","title":"Multi-kingdom microbial changes and their associations with the clinical characteristics in schizophrenia patients","year":2025,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; South China University of Technology; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China; National Key Research and Development Program of China; Guangzhou Medical University","keywords":"Schizophrenia (object-oriented programming); Psychiatry; Medicine; Psychology; Clinical psychology","score_opus":0.035361629979387216,"score_gpt":0.30203399493104033,"score_spread":0.26667236495165314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412048110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830711,0.00005495816,0.00049010717,0.015204916,0.00047516712,0.0002899204,0.00017214858,0.000028775405,0.0002129384],"genre_scores_gemma":[0.99591833,0.000017560518,0.0009440568,0.0029398357,0.00007729996,0.00001142312,0.000025847461,0.00000885507,0.000056779023],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.999155,0.00012241451,0.00021574569,0.00025863078,0.000102288555,0.00014590748],"domain_scores_gemma":[0.9994315,0.00033228568,0.00007935917,0.00010634144,0.000024243931,0.000026252297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001430501,0.00011543461,0.00013621504,0.00007816204,0.00017908237,0.000041567928,0.00014129377,0.000072753486,0.000010708946],"category_scores_gemma":[0.000062803076,0.00007575029,0.00003917848,0.00027190964,0.00015234455,0.000060192913,0.000013585849,0.00022605411,0.000004362981],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047989187,0.0008397567,0.96565664,0.000027882415,0.000030454376,4.2185098e-7,0.0006692765,0.000009620873,0.002335299,0.011281291,0.00097542827,0.01769401],"study_design_scores_gemma":[0.0029163638,0.000032879965,0.9943272,0.000030147334,0.0000066505777,3.5193284e-7,0.000032947057,0.00027715956,0.00007994638,0.0008387423,0.001360276,0.000097364784],"about_ca_topic_score_codex":0.000006835168,"about_ca_topic_score_gemma":0.00089232693,"teacher_disagreement_score":0.028670503,"about_ca_system_score_codex":0.000007553061,"about_ca_system_score_gemma":0.000108078755,"threshold_uncertainty_score":0.3089007},"labels":[],"label_agreement":null},{"id":"W4412123266","doi":"10.22215/cujs.v4i1.4976","title":"The Role of Inflammation in Psychiatric Disorders","year":2025,"lang":"en","type":"article","venue":"Carleton undergraduate journal of science.","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Inflammation; Psychiatry; Medicine; Psychology; Immunology","score_opus":0.006109298011816053,"score_gpt":0.24925822182183593,"score_spread":0.24314892381001987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412123266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96888095,0.0008214771,0.00020158358,0.009888149,0.0009068528,0.00014930365,6.4566e-7,0.00000838458,0.019142644],"genre_scores_gemma":[0.9985794,0.0010623585,0.00007137869,0.00011583273,0.00002743905,0.0000015078559,3.932944e-8,0.000004142378,0.00013790301],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.998324,0.00009421075,0.0005554427,0.0001704786,0.000581049,0.0002748495],"domain_scores_gemma":[0.9989195,0.00030671974,0.00041002122,0.00018919888,0.00011547539,0.000059081332],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009351315,0.000096379816,0.00015758765,0.0007269619,0.00029411653,0.00008982382,0.0008502451,0.000033713728,0.000003022661],"category_scores_gemma":[0.0010169836,0.00006438926,0.00010146065,0.0029339795,0.0012188103,0.00045459974,0.00006689762,0.00021987339,0.0000022390682],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094248506,0.00009521008,0.00734454,0.000018216533,0.0000055112682,0.0000022905144,0.00047480452,0.0009673764,0.7544287,0.1287485,0.0003826631,0.10743796],"study_design_scores_gemma":[0.0013601319,0.00018789561,0.020595979,0.00008761733,0.0000119179895,0.000015171894,0.0030972043,0.0018922499,0.4788221,0.48152438,0.012238625,0.00016671422],"about_ca_topic_score_codex":0.00001401177,"about_ca_topic_score_gemma":0.000060033522,"teacher_disagreement_score":0.35277587,"about_ca_system_score_codex":0.00008514458,"about_ca_system_score_gemma":0.00053941476,"threshold_uncertainty_score":0.44907576},"labels":[],"label_agreement":null},{"id":"W4412181025","doi":"10.21203/rs.3.rs-6882753/v1","title":"Deciphering the Glycoproteomic Landscape of Mood Disorders: Unveiling Molecular Association Between CDG and Depression Resilience","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Depression (economics); Resilience (materials science); Association (psychology); Mood disorders; Mood; Psychology; Medicine; Psychiatry; Neuroscience; Biology; Psychotherapist; Physics; Anxiety","score_opus":0.03062078076718906,"score_gpt":0.3519342756015262,"score_spread":0.32131349483433713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412181025","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99161047,0.0009130557,0.00093117106,0.00073509716,0.00010258143,0.0012816143,0.00009433499,0.00006315403,0.0042685377],"genre_scores_gemma":[0.99839634,0.0009297435,0.00017081367,0.000021968408,0.00006764987,0.00012829271,0.000010592795,0.00002176738,0.00025282567],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959161,0.0010039686,0.00036368216,0.00082739117,0.001308677,0.00058015384],"domain_scores_gemma":[0.9965424,0.0022627444,0.00021862151,0.0007152733,0.00017716512,0.00008382181],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015167445,0.00023032111,0.00032913,0.00028959924,0.00038383855,0.00018275078,0.00091753225,0.00034057428,0.000019757994],"category_scores_gemma":[0.0065116035,0.00018001537,0.0001273982,0.0007095875,0.00021176314,0.000101600985,0.0019460082,0.0014044674,0.000005732573],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036908803,0.00036744843,0.6920114,0.005133362,0.00016329672,0.000017746099,0.0039497325,0.010935136,0.23846969,0.0017874462,0.00077703275,0.046018623],"study_design_scores_gemma":[0.0021940924,0.00026688087,0.3204038,0.004742447,0.00006500606,0.000002404299,0.0030044452,0.012124559,0.6233568,0.03236866,0.00054962584,0.0009212409],"about_ca_topic_score_codex":0.00018031534,"about_ca_topic_score_gemma":0.00009363189,"teacher_disagreement_score":0.38488713,"about_ca_system_score_codex":0.00012830389,"about_ca_system_score_gemma":0.0002709823,"threshold_uncertainty_score":0.7795468},"labels":[],"label_agreement":null},{"id":"W4412388026","doi":"10.1038/s44220-025-00460-0","title":"Proteogenomic signature of Alzheimer’s disease and related dementia risk in individuals with major depressive disorder","year":2025,"lang":"en","type":"article","venue":"Nature Mental Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute on Aging; National Institute of Mental Health; U.S. Department of Health and Human Services","keywords":"Dementia; Disease; Medicine; Signature (topology); Alzheimer's disease; Psychiatry; Psychology; Pathology","score_opus":0.00697811854907774,"score_gpt":0.2750093147134864,"score_spread":0.2680311961644086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412388026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96023905,0.034333307,0.000009108269,0.0026099721,0.00013036329,0.0019315805,0.0003043305,0.000037128633,0.00040516356],"genre_scores_gemma":[0.9977387,0.0005228144,0.00019558484,0.0013774068,0.000005458119,0.000049688966,0.000028426886,0.000016122825,0.000065794644],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99843717,0.00023845157,0.00029278637,0.000480819,0.0002408012,0.00030995626],"domain_scores_gemma":[0.99936265,0.00006834821,0.00022742893,0.00020161195,0.000012802294,0.0001271328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016489119,0.00018469908,0.00023995609,0.00021502994,0.0001929699,0.000018595032,0.00017442033,0.00016140363,0.000030295414],"category_scores_gemma":[0.00008114187,0.00014619042,0.00003662221,0.0005332792,0.00015699511,0.00010860184,0.000099603465,0.0007175018,0.000001721544],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017303639,0.0020614986,0.91304797,0.000985779,0.0004567628,0.000052405343,0.0046661743,0.00014618364,0.020166324,0.009626149,0.004614985,0.042445395],"study_design_scores_gemma":[0.007719578,0.00030908297,0.95778495,0.0005208483,0.00010482801,0.000006759573,0.00041934315,0.00015941985,0.027461749,0.0037917695,0.001366454,0.00035523856],"about_ca_topic_score_codex":0.00008599797,"about_ca_topic_score_gemma":0.0001290663,"teacher_disagreement_score":0.04473695,"about_ca_system_score_codex":0.000041288255,"about_ca_system_score_gemma":0.0002096448,"threshold_uncertainty_score":0.59614724},"labels":[],"label_agreement":null},{"id":"W4412412046","doi":"10.1101/2025.07.13.25331392","title":"Characterization of the suicide attempt-associated chromosome 7 locus","year":2025,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health","keywords":"SNP; Genetics; Locus (genetics); Biology; FOXP2; Haplotype; Genome-wide association study; Genetic association; Gene; Genotype; Single-nucleotide polymorphism; Transcription factor","score_opus":0.02842495136233203,"score_gpt":0.26492321379918915,"score_spread":0.23649826243685712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412412046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943947,0.000029905188,0.00006030755,0.0011886383,0.0013952233,0.0004815773,0.0002625161,0.00009861225,0.0020885116],"genre_scores_gemma":[0.9956527,0.000075216194,0.000003822613,0.00085477094,0.00004687185,0.000032408687,0.000029196355,0.000017677878,0.0032873517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982237,0.00030770228,0.0003674222,0.0004960831,0.00036600002,0.00023909051],"domain_scores_gemma":[0.9986433,0.00015061513,0.00042124622,0.0006913548,0.00005665889,0.000036821646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017497297,0.00022298895,0.0003157857,0.000103168335,0.00010025597,0.000038070757,0.0009280098,0.00023585437,0.00010516827],"category_scores_gemma":[0.0010490683,0.00016875712,0.00019878567,0.0004764413,0.00017012538,0.00004735216,0.000733087,0.0004381077,0.000021116979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008029564,0.000097915836,0.012968739,0.00012264284,0.000012445032,0.0000026103896,0.00019231367,0.000025878615,0.9857409,0.000353987,0.00007910169,0.0003954452],"study_design_scores_gemma":[0.00022942033,0.000010528805,0.16950446,0.0003178676,0.000015764292,6.385846e-7,0.000005999901,0.00013069889,0.8281527,0.00069522986,0.0007665646,0.00017011185],"about_ca_topic_score_codex":0.00003452283,"about_ca_topic_score_gemma":0.00003216628,"teacher_disagreement_score":0.15758818,"about_ca_system_score_codex":0.000055495824,"about_ca_system_score_gemma":0.00018137145,"threshold_uncertainty_score":0.68817157},"labels":[],"label_agreement":null},{"id":"W4412463391","doi":"10.1016/j.cpnec.2025.100312","title":"Clinical, functional and salivary cortisol level changes in individuals with schizophrenia undergoing cognitive behavioral therapy for psychosis in addition to their usual antipsychotic medication","year":2025,"lang":"en","type":"article","venue":"Comprehensive Psychoneuroendocrinology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kingston General Hospital; Queen's University","funders":"Center for Food Safety, University of Georgia; Queen's University","keywords":"Psychosis; Schizophrenia (object-oriented programming); Antipsychotic; Cognition; Clinical psychology; Cognitive behavioral therapy; Medicine; Psychology; Psychiatry","score_opus":0.13051813758420078,"score_gpt":0.3801309119567017,"score_spread":0.2496127743725009,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412463391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893423,0.00030737696,0.0022660638,0.0049746367,0.0010251737,0.0016914532,0.00021891776,0.000074963755,0.00009914523],"genre_scores_gemma":[0.98683363,0.0018378955,0.00058186904,0.010111414,0.00006433052,0.0004465952,0.000059109996,0.000031739673,0.00003340591],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9972754,0.00044464602,0.0005015964,0.001085206,0.00017415552,0.00051898934],"domain_scores_gemma":[0.99734575,0.002019705,0.00017122633,0.00026224848,0.00010095701,0.000100138284],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006261488,0.00031101276,0.00044520048,0.0008150901,0.00014442779,0.000042664626,0.00023393404,0.000096759424,0.000034968965],"category_scores_gemma":[0.00021399463,0.0002873922,0.00005903753,0.0007550446,0.00042686833,0.00013096254,0.00006976508,0.0003818375,0.000008444823],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020894125,0.00673486,0.49501282,0.00021351388,0.00020324854,0.00013676945,0.0016372796,0.00005126398,0.09267624,0.007866057,0.014339231,0.3602346],"study_design_scores_gemma":[0.013559866,0.0022129163,0.97467303,0.00025680286,0.000015169831,0.00006963192,0.0007804908,0.000050058905,0.0033774173,0.0024561307,0.0022327434,0.00031572257],"about_ca_topic_score_codex":0.000015505626,"about_ca_topic_score_gemma":0.00063885364,"teacher_disagreement_score":0.4796602,"about_ca_system_score_codex":0.000026452008,"about_ca_system_score_gemma":0.00008253288,"threshold_uncertainty_score":0.9999578},"labels":[],"label_agreement":null},{"id":"W4412592653","doi":"10.1016/b978-0-443-33580-8.00021-0","title":"Recent theories about the neurobiology of major depression","year":2025,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Neuroscience; Depression (economics); Psychology; Cognitive science; Economics; Keynesian economics","score_opus":0.017343542035536366,"score_gpt":0.25414787312275083,"score_spread":0.23680433108721446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412592653","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022753638,0.00205315,0.0000030803155,0.00033946088,0.000826041,0.00056206656,0.00006690596,0.000060687897,0.99586105],"genre_scores_gemma":[0.0052809305,0.0020115355,0.000016655176,0.00274038,0.00009219648,0.000029336026,0.0000056010067,0.000039700175,0.98978364],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984574,0.00013853885,0.00040324955,0.00053284277,0.00021000055,0.00025801113],"domain_scores_gemma":[0.99832696,0.00054960855,0.00029624457,0.0007294631,0.000053905464,0.000043833264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014884872,0.00032859453,0.0004048876,0.00010967678,0.0001721288,0.000025918183,0.0007205347,0.00026047963,0.0003655702],"category_scores_gemma":[0.00023152478,0.00020642331,0.00020383365,0.000027285223,0.0006880994,0.000020661586,0.00032972379,0.00047482515,0.00005347358],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048280086,0.000008395176,0.0000025312509,0.00005135353,0.000013618788,0.0000043972605,0.00014579644,3.11818e-7,0.0035516352,0.089341976,0.00051400776,0.9063177],"study_design_scores_gemma":[0.00022271252,0.00003980274,0.000041588515,0.00022019603,0.000030349009,0.0000055303076,0.0000071639456,9.2235194e-7,0.025600525,0.052619692,0.921024,0.00018752125],"about_ca_topic_score_codex":3.0792665e-7,"about_ca_topic_score_gemma":0.00001116492,"teacher_disagreement_score":0.92051,"about_ca_system_score_codex":0.00001739962,"about_ca_system_score_gemma":0.00012005373,"threshold_uncertainty_score":0.8417698},"labels":[],"label_agreement":null},{"id":"W4412600830","doi":"10.1038/s41586-025-09265-8","title":"Nanobody therapy rescues behavioural deficits of NMDA receptor hypofunction","year":2025,"lang":"en","type":"article","venue":"Nature","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Agence Nationale de la Recherche","keywords":"NMDA receptor; Neuroscience; Receptor; Psychology; Medicine; Internal medicine","score_opus":0.02116816188496957,"score_gpt":0.2795152905165291,"score_spread":0.25834712863155956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412600830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99145794,0.0010343058,0.000013878803,0.0009901869,0.0010197974,0.0001721444,0.000015634027,0.0000823577,0.0052137445],"genre_scores_gemma":[0.9951647,0.00020971848,0.000092398346,0.0019273062,0.000028831444,0.000007621105,0.000005195941,0.000008782956,0.002555482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999222,0.00006252564,0.00012817248,0.00024678116,0.00019195769,0.00014857521],"domain_scores_gemma":[0.9995899,0.00009454446,0.000051715582,0.00019750308,0.00004456055,0.000021730759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006237105,0.000101092606,0.0001140841,0.00010874321,0.000078970705,0.000018599922,0.00020202411,0.00048548347,0.000110969275],"category_scores_gemma":[0.00026675093,0.0000814742,0.00007447108,0.00046177744,0.00006753723,0.000088343775,0.000027989847,0.00069463835,0.000016061435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015520031,0.000107631924,0.0019899008,0.000011076381,0.000004076167,5.949447e-7,0.00008500436,0.00000247208,0.96115196,0.005546978,0.016526755,0.01441833],"study_design_scores_gemma":[0.0005963391,0.000062640334,0.021727886,0.000026177635,0.00000208259,5.6229834e-7,0.00006418037,0.0000056907948,0.95043874,0.0006575828,0.026332991,0.000085110274],"about_ca_topic_score_codex":0.000012913368,"about_ca_topic_score_gemma":0.0000096104595,"teacher_disagreement_score":0.019737985,"about_ca_system_score_codex":0.000017784352,"about_ca_system_score_gemma":0.000038654292,"threshold_uncertainty_score":0.3744493},"labels":[],"label_agreement":null},{"id":"W4412631526","doi":"10.1186/s13041-025-01234-6","title":"Correction to: Synergistic actions of corticosterone and BDNF on rat hippocampal LTP","year":2025,"lang":"en","type":"erratum","venue":"Molecular Brain","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Occupational Cancer Research Centre; University of Victoria; University of Toronto","funders":"","keywords":"Neuroscience; Long-term potentiation; Psychopharmacology; Hippocampal formation; Corticosterone; LTP induction; Psychology; Hippocampus; Medicine; Psychiatry; Internal medicine; Excitatory postsynaptic potential","score_opus":0.017101344322782524,"score_gpt":0.2768097543882544,"score_spread":0.25970841006547185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412631526","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24210572,0.001532666,0.03237604,0.01601622,0.25057498,0.0047860416,0.0006132015,0.00084671547,0.4511484],"genre_scores_gemma":[0.57104754,0.00011020287,0.00008478731,0.0126072625,0.0002700009,0.0001061517,0.00012350922,0.00009993763,0.41555062],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980324,0.00023544862,0.000320514,0.0007175801,0.00037920717,0.000314878],"domain_scores_gemma":[0.99869776,0.00046171935,0.0001636275,0.000497347,0.00004159543,0.0001379736],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009144678,0.0003253084,0.0003915229,0.00039969632,0.00012754224,0.00006921387,0.00026418062,0.00024718393,0.00006649859],"category_scores_gemma":[0.0037338363,0.00034174003,0.00012500852,0.00054951356,0.00014688267,0.000039179395,0.00013268314,0.0006233022,0.000038359263],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042921678,0.00008236358,0.0000013150429,0.00008203839,0.000011261639,0.000038635775,0.000054763248,0.00005994278,0.36956218,0.00063774636,0.6247171,0.0047097397],"study_design_scores_gemma":[0.0012340576,0.0009817926,0.00068329467,0.0014448211,0.000102566526,0.000036660404,0.00013004345,0.000886916,0.6710148,0.0008146276,0.32167298,0.0009974561],"about_ca_topic_score_codex":0.000039478273,"about_ca_topic_score_gemma":0.000055383425,"teacher_disagreement_score":0.32894182,"about_ca_system_score_codex":0.000074053205,"about_ca_system_score_gemma":0.00022974166,"threshold_uncertainty_score":0.99990344},"labels":[],"label_agreement":null},{"id":"W4412678229","doi":"10.1016/j.bbi.2025.07.023","title":"The moderating role of lifetime social engagement on the relationship between C-reactive protein and negative symptoms among young adults at clinical high risk for psychosis","year":2025,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Mental Health","keywords":"Psychosis; Psychology; C-reactive protein; Clinical psychology; Young adult; Psychiatry; Developmental psychology; Medicine; Internal medicine; Inflammation","score_opus":0.048529112576927366,"score_gpt":0.33537927402963524,"score_spread":0.28685016145270786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412678229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969216,0.00002958452,0.000042113894,0.0009426952,0.000059731243,0.001640557,0.00008515179,0.000023931163,0.00025464306],"genre_scores_gemma":[0.9991266,0.000007696677,0.000039151553,0.00013000965,0.000027769207,0.00041182814,0.000005816593,0.000010827673,0.00024030566],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9977189,0.0013267862,0.00033872863,0.0002758404,0.00015411623,0.0001856827],"domain_scores_gemma":[0.9889876,0.010471171,0.00023789659,0.00022733421,0.000035630415,0.000040316132],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0011885249,0.00014374836,0.00018317786,0.00003978324,0.0026282875,0.000075811455,0.00020515818,0.000104438106,0.0000027597255],"category_scores_gemma":[0.005601282,0.00009437582,0.00010493402,0.00015378123,0.00054102624,0.00009191134,0.00014786891,0.00050913164,5.717979e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042889046,0.00022572858,0.95935965,0.00001506823,0.000034196637,1.697394e-7,0.0046762098,7.006977e-7,0.004649775,0.009369432,0.00017562645,0.021064544],"study_design_scores_gemma":[0.0011547337,0.00019617245,0.98173624,0.000049734375,0.000050125524,1.18604824e-7,0.0019392445,0.000077149874,0.009996447,0.0046620527,0.00003919737,0.00009876992],"about_ca_topic_score_codex":0.00036100377,"about_ca_topic_score_gemma":0.000116931194,"teacher_disagreement_score":0.022376597,"about_ca_system_score_codex":0.00002974538,"about_ca_system_score_gemma":0.000026257418,"threshold_uncertainty_score":0.99867016},"labels":[],"label_agreement":null},{"id":"W4412813856","doi":"10.20944/preprints202507.2669.v1","title":"Beyond Joints: Neuropsychiatric Benefits of TNF-α and IL-6 Inhibitors in Rheumatoid Arthritis – a Narrative Review","year":2025,"lang":"en","type":"review","venue":"Preprints.org","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McMaster University","keywords":"Rheumatoid arthritis; Narrative; Narrative review; Tumor necrosis factor alpha; Medicine; Immunology; Psychology; Intensive care medicine; Art; Literature","score_opus":0.06506399934859047,"score_gpt":0.3352472041796607,"score_spread":0.2701832048310702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412813856","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007628274,0.9844286,3.691487e-7,0.00016851473,0.0004735987,0.0019214118,0.000091084235,0.000064859305,0.0052232803],"genre_scores_gemma":[0.0020830773,0.9969001,0.000014740614,0.0004338067,0.00002961045,0.00023315224,0.000010566218,0.000044982087,0.00025000086],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99571764,0.000746688,0.0014151294,0.0013509418,0.00036806878,0.00040155297],"domain_scores_gemma":[0.99769723,0.0005306277,0.0007452765,0.0008471356,0.000055961944,0.00012373582],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050517893,0.0005739043,0.0021301846,0.0005989184,0.0000946936,0.000017332257,0.00062563474,0.00024040244,0.00021093254],"category_scores_gemma":[0.0028208154,0.00053377356,0.00041799515,0.0019208348,0.00022569283,0.00017031256,0.0006751024,0.0007210367,0.00017047269],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011668815,0.00028856902,0.0011574571,0.06969644,0.00002944378,0.000021817676,0.000570737,0.0000010532302,0.00005761233,0.0014133186,0.0005777226,0.92617416],"study_design_scores_gemma":[0.0011799994,0.00009600894,0.0031168612,0.33291146,0.000105805695,0.00015777753,0.00011046549,9.626839e-7,0.0010200045,0.000875047,0.659156,0.0012696042],"about_ca_topic_score_codex":0.000022905124,"about_ca_topic_score_gemma":0.000028460117,"teacher_disagreement_score":0.9249046,"about_ca_system_score_codex":0.000049015372,"about_ca_system_score_gemma":0.00032674448,"threshold_uncertainty_score":0.9997114},"labels":[],"label_agreement":null},{"id":"W4412828844","doi":"10.1016/j.neubiorev.2026.106699","title":"Neuromarkers of Post-Traumatic Stress Disorder: A Systematic Review of Positron Emission Tomography Studies","year":2025,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Shahid Beheshti University of Medical Sciences","keywords":"Positron emission tomography; Traumatic stress; Nuclear medicine; Medicine; Brain positron emission tomography; Psychology; Medical physics; Preclinical imaging; Clinical psychology; Biology","score_opus":0.09337392687680018,"score_gpt":0.3973441287701537,"score_spread":0.3039702018933535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412828844","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015705718,0.9888475,0.0000074506256,0.000010726369,0.00075910316,0.0096902475,0.00034489355,0.00008452181,0.00009852715],"genre_scores_gemma":[0.00007794565,0.99797827,0.000050758503,0.0007966736,0.00001222122,0.0008198256,0.000021756789,0.00006295439,0.00017960742],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9896402,0.0022579203,0.0044307653,0.0016220713,0.001298026,0.00075106457],"domain_scores_gemma":[0.9930492,0.00017513528,0.0042795646,0.0020172128,0.00023872025,0.0002401594],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013670719,0.0012435827,0.00824365,0.0009514477,0.00022800687,0.0000660629,0.0026763135,0.0002512481,0.000030695523],"category_scores_gemma":[0.010906575,0.0008245614,0.0027423531,0.004740577,0.0010555425,0.0003485604,0.0006078947,0.0006226227,0.000013919356],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000033182578,0.00037455893,0.0000056104464,0.77066565,9.2031377e-7,0.000010918798,0.00006288207,4.201774e-8,0.0009586282,0.000024779602,0.00026172004,0.22763094],"study_design_scores_gemma":[0.00011501681,0.00042042314,0.000007469017,0.83718765,0.0020842487,0.000034975707,0.000094079514,0.0000011503486,0.00010662686,0.0000043690657,0.15940705,0.0005369702],"about_ca_topic_score_codex":0.000024203724,"about_ca_topic_score_gemma":0.0000070363903,"teacher_disagreement_score":0.22709398,"about_ca_system_score_codex":0.00007620001,"about_ca_system_score_gemma":0.00042338602,"threshold_uncertainty_score":0.9994205},"labels":[],"label_agreement":null},{"id":"W4412864574","doi":"10.1101/2025.07.31.25332511","title":"Distinct Neurodevelopmental Signatures of Sex-Specific Transcriptome-Based Polygenic Risk Scores for Depression","year":2025,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Calgary; Centre for Addiction and Mental Health","funders":"Natural Sciences and Engineering Research Council of Canada; Centre for Addiction and Mental Health Foundation","keywords":"Major depressive disorder; Transcriptome; Depression (economics); Sex characteristics; Psychology; Clinical psychology; Medicine; Gene; Biology; Internal medicine; Psychiatry; Gene expression; Cognition; Genetics","score_opus":0.026501258050940845,"score_gpt":0.26764983518919666,"score_spread":0.24114857713825583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412864574","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9880592,0.0011193631,0.0057288217,0.000120473596,0.0015796362,0.00126053,0.0013103815,0.00019372367,0.00062785635],"genre_scores_gemma":[0.99758244,0.00020647571,0.001169395,0.00023773208,0.00006798381,0.00020126265,0.00006456396,0.000047958445,0.00042219218],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969961,0.0002903771,0.0005774646,0.001214797,0.00047952298,0.00044171605],"domain_scores_gemma":[0.9979967,0.0007956429,0.00034480958,0.0007042098,0.00005119529,0.000107452026],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002450763,0.00047588756,0.00053835596,0.00034604623,0.00021741341,0.000065457854,0.0010663774,0.0003155578,0.00008752979],"category_scores_gemma":[0.00048804152,0.00042239446,0.0004430286,0.00031656548,0.00026117256,0.000052602194,0.00027182573,0.00069549057,0.000004591659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00096159225,0.0005931184,0.06801404,0.0013693951,0.000046927573,0.000018120218,0.0007670651,0.0013076261,0.8988601,0.00021488589,0.0021048645,0.025742298],"study_design_scores_gemma":[0.0016385171,0.00007342058,0.15655145,0.0003293568,0.000036937698,9.5350174e-7,0.000034633144,0.0014549023,0.8329377,0.0011947722,0.005207621,0.0005396954],"about_ca_topic_score_codex":0.000022794819,"about_ca_topic_score_gemma":0.000018664176,"teacher_disagreement_score":0.0885374,"about_ca_system_score_codex":0.000042065018,"about_ca_system_score_gemma":0.00027260854,"threshold_uncertainty_score":0.9998228},"labels":[],"label_agreement":null},{"id":"W4412928703","doi":"10.1001/jamanetworkopen.2025.25147","title":"Latent Profile Analysis of Childhood Maltreatment and Neural Markers in Depression","year":2025,"lang":"en","type":"article","venue":"JAMA Network Open","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McMaster University; Indoc Research; Baycrest Hospital; Centre for Addiction and Mental Health; Dalhousie University; Hotchkiss Brain Institute; University of Toronto; University of Calgary; University of British Columbia; St. Joseph’s Healthcare Hamilton; St. Michael's Hospital; Queen's University","funders":"","keywords":"Major depressive disorder; Anhedonia; Bipolar disorder; Antidepressant; Depression (economics); Aripiprazole; Psychology; Psychiatry; Escitalopram; Clinical psychology; Suicidal ideation; Citalopram; Medicine; Internal medicine; Schizophrenia (object-oriented programming); Poison control; Injury prevention; Mood","score_opus":0.014505867120500476,"score_gpt":0.27184514632538986,"score_spread":0.2573392792048894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412928703","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887978,0.00032232594,0.0000151610075,0.0005801896,0.000066557244,0.0005961875,0.000009895489,0.000013011642,0.009598896],"genre_scores_gemma":[0.99828917,0.00012520001,0.00018059224,0.0007774116,0.000009833673,0.000046923684,0.0000081568105,0.00000542889,0.0005572954],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989792,0.00016402654,0.00021129739,0.00033918646,0.000101561025,0.00020471678],"domain_scores_gemma":[0.99948156,0.0001740055,0.00007788889,0.00021927326,0.000008321376,0.000038925507],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018707545,0.00010105354,0.0002507269,0.00015295751,0.000066155335,0.00008329884,0.00029978316,0.000050991457,0.00011259541],"category_scores_gemma":[0.000075244105,0.00008139739,0.0000559374,0.0013121058,0.00004547185,0.00014298626,0.00036601225,0.00008893153,0.0000016505708],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044646836,0.00033780764,0.88827384,0.000020263135,0.00016347897,0.000020159014,0.0002670023,0.00942493,0.0011524141,0.00075895205,0.0029998464,0.096134864],"study_design_scores_gemma":[0.001064785,0.00003541718,0.9788785,0.000073590796,0.00006555756,5.872598e-7,0.000044023735,0.017434267,0.0019002688,0.00022335189,0.00020206111,0.00007759195],"about_ca_topic_score_codex":0.00014321372,"about_ca_topic_score_gemma":0.00013651278,"teacher_disagreement_score":0.09605727,"about_ca_system_score_codex":0.000019707339,"about_ca_system_score_gemma":0.000024202645,"threshold_uncertainty_score":0.3319289},"labels":[],"label_agreement":null},{"id":"W4413108147","doi":"10.1177/1540658x251365257","title":"Drug Repurposing Patent Applications January–March 2025","year":2025,"lang":"en","type":"article","venue":"Assay and Drug Development Technologies","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Drug repositioning; Repurposing; Drug discovery; Drug; Business; Computer science; Pharmacology; Medicine; Bioinformatics; Biology","score_opus":0.025408957332635335,"score_gpt":0.25910713842202276,"score_spread":0.23369818108938742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413108147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7645312,0.011220273,0.028284825,0.057474423,0.00084805477,0.004475884,0.000024823734,0.009863079,0.12327745],"genre_scores_gemma":[0.98671687,0.0010184422,0.004530333,0.00055971,0.0000053054737,0.0004449238,0.000005079206,0.000008921967,0.006710397],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986525,0.000047150006,0.00027154438,0.0005413,0.0001693006,0.00031816598],"domain_scores_gemma":[0.9992506,0.00030093384,0.00006463547,0.00033130718,0.000027247099,0.000025306008],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026589076,0.00017963458,0.00016957281,0.0003068883,0.0005026574,0.00009270869,0.0004182799,0.000092137205,0.000006588778],"category_scores_gemma":[0.0003331585,0.00015735859,0.00003163238,0.0007210778,0.00028946035,0.000117187934,0.00045348582,0.0002236528,0.000040526993],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017049711,0.00015961504,0.0031777613,0.00010391812,0.000021007201,0.0000103101,0.00053094176,0.0000048129327,0.025148218,0.055826068,0.01745531,0.897545],"study_design_scores_gemma":[0.00032727036,0.0000055334635,0.0025823137,0.000083679464,0.0000057798743,0.0000034302175,0.0024123213,0.000040567094,0.5986257,0.020986106,0.37464347,0.00028376887],"about_ca_topic_score_codex":0.000006612838,"about_ca_topic_score_gemma":0.00001733628,"teacher_disagreement_score":0.8972612,"about_ca_system_score_codex":0.000049868122,"about_ca_system_score_gemma":0.00011899474,"threshold_uncertainty_score":0.6416897},"labels":[],"label_agreement":null},{"id":"W4413178389","doi":"10.3389/fpsyt.2025.1632304","title":"Editorial: Molecular mechanisms in psychiatry 2023: anxiety and stress","year":2025,"lang":"en","type":"editorial","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Anxiety; Psychiatry; Psychology; Stress (linguistics); Medicine; Clinical psychology; Philosophy","score_opus":0.0033125133310261336,"score_gpt":0.23455637174726485,"score_spread":0.2312438584162387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413178389","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00030146565,0.0049976096,0.0013942398,0.0007362823,0.98816967,0.00078131625,0.0008402455,0.00013097498,0.0026481778],"genre_scores_gemma":[0.00013380843,0.0031286387,0.011544008,0.00072431867,0.98314846,0.00015720914,0.00017425808,0.00013700785,0.0008522768],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9946499,0.00039289682,0.0008689106,0.001908923,0.001229021,0.0009503398],"domain_scores_gemma":[0.9983213,0.00018942686,0.00032894826,0.0009118002,0.00005643618,0.00019210535],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00044939597,0.00082027476,0.0009754536,0.0011010353,0.00013968073,0.0001907376,0.0012368674,0.002209787,0.000026844666],"category_scores_gemma":[0.00085982314,0.00091079884,0.0002467297,0.0013774917,0.00021746132,0.00023262989,0.00031318943,0.002600334,0.000010419482],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017953388,0.0003982325,0.0014189004,0.0005522874,0.000023686098,0.000010147566,0.000063529005,0.000022005608,0.000117609074,0.002244011,0.99423885,0.0007312328],"study_design_scores_gemma":[0.004000234,0.00012539518,0.00017980846,0.0011808131,0.000046932513,0.0000015132163,0.00058830954,0.00008631287,0.0002734024,0.09358046,0.89871746,0.0012193532],"about_ca_topic_score_codex":0.00010675866,"about_ca_topic_score_gemma":0.00047265002,"teacher_disagreement_score":0.09552136,"about_ca_system_score_codex":0.00018935425,"about_ca_system_score_gemma":0.0014089163,"threshold_uncertainty_score":0.9997007},"labels":[],"label_agreement":null},{"id":"W4413284442","doi":"10.1093/ijnp/pyaf052.003","title":"103. EARLY ANTIBIOTIC EXPOSURE AND RISK OF PSYCHIATRIC INCREASED SENSITIVITY OF CENTRAL SEROTONERGIC NEURONS TO CORTICOSTEROIDS FOLLOWING MATERNAL IMMUNE ACTIVATION: SIGNIFICANCE FOR MOOD DISORDERS AND NEUROCOGNITIVE OUTCOMES: RESULTS OF A SYSTEMATIC REVIEW AND META-ANALYSIS","year":2025,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Serotonergic; Neurocognitive; Mood; Medicine; Psychiatry; Mood disorders; Immune system; Serotonin; Internal medicine; Cognition; Anxiety; Immunology","score_opus":0.022530470982844403,"score_gpt":0.316913929657219,"score_spread":0.2943834586743746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413284442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937679,0.0009831636,0.0006600484,0.002837059,0.00025467837,0.0012521851,0.00022194856,0.00000484487,0.000018160737],"genre_scores_gemma":[0.9968217,0.0018278612,0.00010039762,0.0011900809,0.000010020996,0.000016106327,8.4003904e-7,0.000011075279,0.0000219308],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9970031,0.001055917,0.0011654556,0.00028433013,0.00033438392,0.00015684956],"domain_scores_gemma":[0.99546087,0.0025204418,0.001518357,0.00016849222,0.00026161567,0.00007025508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073642103,0.00019341464,0.0011730507,0.00040825977,0.000061529085,0.000025724808,0.00033327943,0.00003439574,0.000004199903],"category_scores_gemma":[0.0016992087,0.000132016,0.00047340614,0.0005247405,0.00016615256,0.00013839299,0.00009407072,0.00019220509,1.1031425e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0049898066,0.00070793356,0.029801063,0.008834547,0.034534935,0.000029335737,0.0006518623,0.0005706762,0.9194366,0.0001211132,0.000043214586,0.0002789222],"study_design_scores_gemma":[0.0072246646,0.0012851927,0.8322042,0.0007489246,0.1085947,0.00008950844,0.00014315195,0.0005997616,0.048604928,0.00025893032,0.000004127932,0.00024188957],"about_ca_topic_score_codex":0.000073005445,"about_ca_topic_score_gemma":0.00001742464,"teacher_disagreement_score":0.87083167,"about_ca_system_score_codex":0.000010672833,"about_ca_system_score_gemma":0.000044433615,"threshold_uncertainty_score":0.53834563},"labels":[],"label_agreement":null},{"id":"W4413284510","doi":"10.1093/ijnp/pyaf052.105","title":"688. TEMPORAL IMMUNE EFFECTS OF ORAL KETAMINE ON PTSD: TRANSCRIPTOMIC EVIDENCE OF SHORT-TERM INFLAMMATION SUPPRESSION AND LONG-TERM IMMUNE REMODELLING","year":2025,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"Term (time); Inflammation; Immune system; Ketamine; Neuroscience; Medicine; Immunology; Psychology","score_opus":0.029875597559696862,"score_gpt":0.34106671115509135,"score_spread":0.3111911135953945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413284510","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992743,0.00096884585,0.00073806086,0.0022646058,0.0029234688,0.00027668435,0.000004046803,0.0000106272,0.000070650916],"genre_scores_gemma":[0.9972528,0.0020827355,0.000041055613,0.00043370432,0.00009068745,0.000003962473,0.0000010476482,0.00001407328,0.00007991903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99791235,0.00040259422,0.00086345617,0.00021424968,0.00044702805,0.00016035221],"domain_scores_gemma":[0.9979467,0.0010667905,0.0005795831,0.0001691567,0.00019439984,0.000043396634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038865808,0.00017350492,0.0003443299,0.00038351666,0.000059765352,0.000027259059,0.0008534462,0.00006233752,0.00003643806],"category_scores_gemma":[0.00029913307,0.00012670344,0.00016667973,0.00019849064,0.000271452,0.0002780902,0.00009264429,0.00039567729,0.0000014526369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036931187,0.00019092392,0.0014719645,0.00011751493,0.00007347395,0.000091872695,0.0002633609,0.0004192796,0.9830018,0.00015060852,0.00006527806,0.010460751],"study_design_scores_gemma":[0.0025607422,0.0005297878,0.09201537,0.0007509504,0.0000644236,0.0001266071,0.000012500651,0.001139028,0.9024129,0.00026074875,0.000037829264,0.0000891288],"about_ca_topic_score_codex":0.0000060648,"about_ca_topic_score_gemma":0.0000019534543,"teacher_disagreement_score":0.090543404,"about_ca_system_score_codex":0.000034207264,"about_ca_system_score_gemma":0.00006542198,"threshold_uncertainty_score":0.5166816},"labels":[],"label_agreement":null},{"id":"W4413284748","doi":"10.1093/ijnp/pyaf052.361","title":"540. INFLAMMATION AND AGING IN PSYCHOSIS – A TRANSDIAGNOSTIC PROTEOMICS STUDY USING THE HUMAN CONNECTOME PROJECT FOR EARLY PSYCHOSIS (HCP-EP)","year":2025,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"École de Technologie Supérieure; University of Saskatchewan","funders":"","keywords":"Psychosis; Connectome; Neuroscience; Psychology; Inflammation; Medicine; Psychiatry; Functional connectivity; Internal medicine","score_opus":0.047829738391849466,"score_gpt":0.3899723411277622,"score_spread":0.34214260273591274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413284748","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855708,0.00006334001,0.0005621382,0.010418229,0.0017137907,0.0015553116,0.000007760847,0.000013530728,0.000095132214],"genre_scores_gemma":[0.9969515,0.00012487824,0.00008666717,0.0024307098,0.00024152455,0.00010677998,2.7240054e-7,0.000017589098,0.000040042447],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981607,0.00046439754,0.00060165976,0.00026258285,0.00029943403,0.00021121667],"domain_scores_gemma":[0.9980638,0.0012436796,0.00037538042,0.00012969889,0.00015747843,0.000029979074],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006369653,0.00016307864,0.00020273091,0.0004807655,0.00020547192,0.00013747832,0.0009190908,0.000041173513,0.000014292995],"category_scores_gemma":[0.00036156728,0.0001088223,0.00010178762,0.00039499896,0.00016337476,0.00020666973,0.000057441328,0.00041078593,8.1175233e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011221821,0.000465365,0.0075629223,0.000017394663,0.000119932054,0.000044895904,0.0033853112,0.0003909354,0.9822651,0.0004913504,0.0005143194,0.0036202974],"study_design_scores_gemma":[0.075973645,0.0052120113,0.5691675,0.0008524826,0.00084269047,0.0012513282,0.0063493834,0.014999679,0.28774887,0.02567481,0.010491914,0.0014357055],"about_ca_topic_score_codex":0.00004416122,"about_ca_topic_score_gemma":0.000045020515,"teacher_disagreement_score":0.69451624,"about_ca_system_score_codex":0.000059159218,"about_ca_system_score_gemma":0.000058968733,"threshold_uncertainty_score":0.44376445},"labels":[],"label_agreement":null},{"id":"W4413284965","doi":"10.1093/ijnp/pyaf052.288","title":"471. MATERNAL IMMUNE ACTIVATION LEADS TO SCHIZOPHRENIA-RELATED BEHAVIOURAL AND NEUROPHYSIOLOGICAL DEFICITS IN MOTHERS AND JUVENILE OFFSPRING","year":2025,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Offspring; Juvenile; Schizophrenia (object-oriented programming); Neurophysiology; Neuroscience; Psychology; Immune system; Medicine; Developmental psychology; Psychiatry; Pregnancy; Biology; Immunology; Genetics","score_opus":0.020400950657607626,"score_gpt":0.3020771954087145,"score_spread":0.2816762447511069,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413284965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98937035,0.000065207314,0.000026620073,0.008893244,0.0012862566,0.00014456075,0.0000025302797,0.000014016208,0.00019724225],"genre_scores_gemma":[0.9951588,0.00017128495,0.000037356414,0.004460726,0.00005184002,0.0000045307243,2.0073885e-7,0.000010978974,0.00010427638],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987176,0.00023258921,0.00044933936,0.00022100136,0.00020748562,0.00017195614],"domain_scores_gemma":[0.9992759,0.00032536563,0.00020735511,0.00007328286,0.00006260083,0.000055469947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017924893,0.00013147703,0.00018748142,0.0003410062,0.000068998546,0.000062233885,0.0005236512,0.000047663256,0.000048177993],"category_scores_gemma":[0.00023365083,0.00009680645,0.00005135831,0.00023191629,0.00015078596,0.00014873756,0.00016877071,0.00043596522,0.0000056756207],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014702732,0.000080431804,0.0030354268,0.000002934024,0.000013759055,0.00009025156,0.0001311992,0.000418392,0.98757833,0.00060968427,0.00008998758,0.0064793006],"study_design_scores_gemma":[0.0041082497,0.00030732487,0.8345892,0.00006682056,0.000016828395,0.00039475257,0.00005268282,0.000635684,0.15798931,0.0013937711,0.00030757027,0.000137803],"about_ca_topic_score_codex":0.000014469077,"about_ca_topic_score_gemma":0.000002318719,"teacher_disagreement_score":0.83155376,"about_ca_system_score_codex":0.000034947567,"about_ca_system_score_gemma":0.000032133274,"threshold_uncertainty_score":0.39476523},"labels":[],"label_agreement":null},{"id":"W4413288787","doi":"10.1186/s12888-025-07263-8","title":"The associations of suicidal ideation with psychopathology and inflammatory cytokines in patients with chronic schizophrenia","year":2025,"lang":"en","type":"article","venue":"BMC Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Psychopathology; Suicidal ideation; Schizophrenia (object-oriented programming); Psychiatry; Clinical psychology; Psychology; Medicine; Poison control; Human factors and ergonomics; Medical emergency","score_opus":0.0073786680470992565,"score_gpt":0.238469882392287,"score_spread":0.23109121434518776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413288787","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980789,0.0001658288,0.0001242486,0.00032398733,0.00026222222,0.00029981288,0.000010376336,0.000024158899,0.0007104878],"genre_scores_gemma":[0.9993991,0.000012096892,0.0003336703,0.00014476683,0.000022973865,0.0000233953,0.0000028646543,0.000008272225,0.00005285448],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99920076,0.00008993633,0.00019101035,0.0002190349,0.0001387952,0.0001604559],"domain_scores_gemma":[0.99952173,0.00010905505,0.00012845,0.00019158497,0.000030499914,0.00001865155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009129401,0.00009841606,0.00011018571,0.00011532651,0.00013878041,0.000022865584,0.0001326696,0.00005127012,0.0000026752105],"category_scores_gemma":[0.00009146879,0.00006341683,0.000018242565,0.00039075222,0.00017544937,0.00008974565,0.000022836537,0.000110531495,0.0000015889219],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035205416,0.00006782176,0.9836729,0.000026809874,0.0000040168065,6.686037e-8,0.000029814562,0.00003944011,0.0003196799,0.014865575,0.000084277104,0.0005375033],"study_design_scores_gemma":[0.0029816043,0.000141812,0.9944662,0.000041658353,0.000006178372,4.662918e-7,0.00002869504,0.000030957846,0.00024844508,0.0019175658,0.00006217418,0.0000742667],"about_ca_topic_score_codex":0.00001503316,"about_ca_topic_score_gemma":0.0049750316,"teacher_disagreement_score":0.012948009,"about_ca_system_score_codex":0.000027346367,"about_ca_system_score_gemma":0.00022866561,"threshold_uncertainty_score":0.27761844},"labels":[],"label_agreement":null},{"id":"W4413371468","doi":"10.1016/j.bpsgos.2025.100598","title":"Decreased Mitochondrial DNA Integrity and Elevated Inflammatory Markers in Late-Life Depression: A Longitudinal Study","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry Global Open Science","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Saskatchewan; Centre for Addiction and Mental Health","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Canada Research Chairs; Ontario Ministry of Health and Long-Term Care; Centre for Addiction and Mental Health; Canada Foundation for Innovation; Canadian Institutes of Health Research; Weston Brain Institute; Centre for Addiction and Mental Health Foundation; National Alliance for Research on Schizophrenia and Depression; BrightFocus Foundation; Fondation Brain Canada; National Institute of Mental Health; University of Saskatchewan; Ontario Ministry of Research and Innovation; National Institute of Mental Health and Neurosciences; Brain and Behavior Research Foundation","keywords":"Mitochondrial DNA; Depression (economics); Late life depression; Biology; Genetics; Medicine; Endocrinology; Gene","score_opus":0.049256836302918806,"score_gpt":0.34587558929935136,"score_spread":0.29661875299643253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413371468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99166083,0.00011857625,0.00005654054,0.0008850806,0.0012279577,0.001363242,0.000015951924,0.000075260956,0.0045965705],"genre_scores_gemma":[0.9973704,0.000017974084,0.0005940064,0.0019129751,0.000031603522,0.000036861085,0.0000010279001,0.0000034067,0.000031719715],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.996645,0.00043601022,0.00047273378,0.001457884,0.0004036861,0.0005847392],"domain_scores_gemma":[0.9988249,0.00020611894,0.00012272915,0.00046933885,0.000051679384,0.00032525507],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00090244215,0.00027149208,0.00034553962,0.00013763682,0.0004469461,0.0004409629,0.0024590266,0.00015738259,0.00008316783],"category_scores_gemma":[0.0035888327,0.0001914726,0.00005503824,0.0024573677,0.0012787795,0.00047968057,0.0015756622,0.00037503472,0.000020695274],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011621393,0.000748458,0.97848064,0.000007071353,0.0000046160358,0.000020900034,0.000025402818,0.000010667823,0.013239507,0.0047837235,0.00054828054,0.0009686168],"study_design_scores_gemma":[0.0026049924,0.00026585397,0.9884457,0.00005908594,0.000004519247,0.000004496371,0.0003525994,0.00022915086,0.00047964658,0.007078685,0.0002203786,0.0002549151],"about_ca_topic_score_codex":0.00029471354,"about_ca_topic_score_gemma":0.0003944563,"teacher_disagreement_score":0.01275986,"about_ca_system_score_codex":0.00010814431,"about_ca_system_score_gemma":0.00090964197,"threshold_uncertainty_score":0.7808026},"labels":[],"label_agreement":null},{"id":"W4413443240","doi":"10.1161/jaha.125.042820","title":"Inflammatory Status Modifies the Association Between Glycemic Traits and Cognitive Impairment in Patients With Coronary Artery Disease","year":2025,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Coronary artery disease; Glycemic; Internal medicine; Disease; Cognitive impairment; Cardiology; Diabetes mellitus; Association (psychology); Endocrinology; Insulin","score_opus":0.007021278098903421,"score_gpt":0.23566704551471596,"score_spread":0.22864576741581252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413443240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99725056,0.000026826003,0.00000801285,0.0022708774,0.000079776735,0.00029473111,0.000026272348,0.000007180652,0.000035794947],"genre_scores_gemma":[0.9983822,0.000027377186,0.0000060861944,0.0014575183,0.000034446486,0.00000579641,8.1446103e-7,0.000006461789,0.00007928713],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983878,0.0005052394,0.00027833678,0.00011409819,0.0004986978,0.00021583667],"domain_scores_gemma":[0.998,0.0011211014,0.00066060695,0.00005476286,0.00010884362,0.000054668588],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037394906,0.0000945811,0.00022680195,0.00009790047,0.00014548328,0.000051788036,0.00010716113,0.000025797692,0.000001875438],"category_scores_gemma":[0.0011814374,0.000057203346,0.0000755103,0.0003633291,0.0000840041,0.0002054193,0.000039103015,0.0002590672,0.0000015653134],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058801606,0.00007945673,0.99652994,0.0000048655816,0.000052949985,9.204398e-7,0.00041518183,0.00003101713,0.00021652677,0.0000065809813,0.00031356682,0.0017609644],"study_design_scores_gemma":[0.0016202382,0.00021323557,0.9971514,0.00007209708,0.00006346513,4.153279e-7,0.00032739306,0.000022170952,0.0001493777,0.00023151202,0.00008502999,0.0000636632],"about_ca_topic_score_codex":0.000011303518,"about_ca_topic_score_gemma":0.000014543381,"teacher_disagreement_score":0.0016973013,"about_ca_system_score_codex":0.00056151225,"about_ca_system_score_gemma":0.00017621022,"threshold_uncertainty_score":0.23326847},"labels":[],"label_agreement":null},{"id":"W4413612243","doi":"10.3389/fimmu.2025.1644783","title":"MicroRNA-132 regulates quinolinic acid production in the brain during LPS-induced neuroinflammation","year":2025,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada","keywords":"Quinolinic acid; Neuroinflammation; microRNA; Chemistry; Cell biology; Neuroscience; Medicine; Biology; Inflammation; Immunology; Biochemistry; Gene","score_opus":0.01314472407423733,"score_gpt":0.2440710555893063,"score_spread":0.23092633151506897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413612243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98740053,0.00040355636,0.000023681989,0.00842601,0.002521898,0.0005244173,8.869244e-7,0.00006513216,0.00063390826],"genre_scores_gemma":[0.99851847,0.00012364614,0.00011920296,0.0005045935,0.00003269607,0.000050658055,0.0000027208473,0.000011758848,0.00063626305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981738,0.00052227377,0.00035665205,0.00048496123,0.00010083395,0.00036151096],"domain_scores_gemma":[0.99932486,0.00010176412,0.00010464216,0.00044588748,0.00001302001,0.000009804401],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028941265,0.00015178767,0.0002056915,0.0005409948,0.00010982826,0.00003581659,0.0004922368,0.0001448576,0.000008755807],"category_scores_gemma":[0.0009522438,0.00013425722,0.000052656575,0.0009524755,0.00016392191,0.00020113224,0.000082058614,0.00041555314,0.000016731747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016558524,0.000063269166,0.0033674631,0.000022261973,0.000005638357,0.000011350166,0.0009298109,0.00002387263,0.9888515,0.0004926444,0.0010394658,0.0050271684],"study_design_scores_gemma":[0.0009734069,0.000044663047,0.17682491,0.00004481216,0.0000022649472,0.000021037678,0.0010237243,0.00006859406,0.8157638,0.0042897332,0.00081663084,0.00012642237],"about_ca_topic_score_codex":0.00002193408,"about_ca_topic_score_gemma":0.000055789977,"teacher_disagreement_score":0.17345744,"about_ca_system_score_codex":0.00009438833,"about_ca_system_score_gemma":0.00005257048,"threshold_uncertainty_score":0.54748505},"labels":[],"label_agreement":null},{"id":"W4413805647","doi":"10.1007/s00213-025-06878-9","title":"Investigating the relationship between gut microbiota and electrocortical signatures of feedback processing: an ERP study","year":2025,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Trent University; Nottingham Trent University","keywords":"Gut–brain axis; Prefrontal cortex; Gut flora; Electroencephalography; Psychology; Microbiome; Anterior cingulate cortex; Neurophysiology; Neuroscience; Event-related potential; Ventromedial prefrontal cortex; Brain activity and meditation; Cognition; Biology; Bioinformatics; Immunology","score_opus":0.05034338608710564,"score_gpt":0.3735150963487211,"score_spread":0.32317171026161545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413805647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99597615,0.00022459684,0.00003898177,0.0022192753,0.00013554098,0.0005613574,0.000003566716,0.000048884733,0.0007916274],"genre_scores_gemma":[0.99730384,0.0000050754506,0.000094062605,0.0023608655,0.000054291668,0.000033720073,0.0000011239669,0.000010389799,0.0001366409],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985764,0.00041247663,0.00028101495,0.00038521658,0.000101348,0.00024356651],"domain_scores_gemma":[0.99855685,0.0010876529,0.00010623866,0.00015686975,0.000029019884,0.00006333697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002211264,0.00012927531,0.00017287086,0.000117063304,0.00027209785,0.000036961712,0.0003303128,0.000087320586,0.000021723688],"category_scores_gemma":[0.0005581004,0.00009776873,0.000026775528,0.0005994781,0.00045162946,0.00009309442,0.00006658038,0.00040832852,0.0000035606624],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055009903,0.00021908835,0.177804,0.000033464985,0.000010932414,0.0000010208759,0.0008042258,0.0000035482801,0.81617415,0.0011039644,0.0008465333,0.0029440855],"study_design_scores_gemma":[0.0017310696,0.00024024959,0.96174604,0.000014784376,0.000050970593,0.0000023907148,0.00039176727,0.000114455084,0.029253654,0.006089724,0.00024707033,0.000117809104],"about_ca_topic_score_codex":0.0000051180573,"about_ca_topic_score_gemma":0.000008135838,"teacher_disagreement_score":0.7869205,"about_ca_system_score_codex":0.000011720143,"about_ca_system_score_gemma":0.000078797726,"threshold_uncertainty_score":0.39868933},"labels":[],"label_agreement":null},{"id":"W4413885048","doi":"10.1016/j.jcmgh.2026.101811","title":"Dietary Tryptophan Enhances Aryl Hydrocarbon Receptor Activation and Reduces Colitis Through Microbial Metabolism","year":2025,"lang":"en","type":"article","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Canada; Astellas Pharma; AstraZeneca; Agence Nationale de la Recherche; Biocodex Microbiota Foundation; Danone; McMaster University","keywords":"Aryl hydrocarbon receptor; Tryptophan; Chemistry; Metabolism; Microbial metabolism; Receptor; Aryl; Hydrocarbon; Colitis; Biochemistry; Environmental chemistry; Internal medicine; Organic chemistry; Biology; Medicine; Bacteria; Amino acid; Genetics","score_opus":0.009722291311172445,"score_gpt":0.23335887447787748,"score_spread":0.22363658316670504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413885048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993334,0.0013887712,0.0016227938,0.0025814294,0.00033515133,0.00022985123,0.000010258198,0.00004246423,0.0004552679],"genre_scores_gemma":[0.99216735,0.0015309831,0.00026815446,0.005874238,0.00003052268,0.000027962114,0.000017867222,0.000012497172,0.000070450864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984144,0.00024206044,0.00023481809,0.00064652174,0.00006305471,0.00039913747],"domain_scores_gemma":[0.9996067,0.00007109867,0.00008353486,0.00014736723,0.000016051421,0.00007523736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000075151554,0.00023247433,0.00037722924,0.00012347168,0.00021573124,0.000034257595,0.00011862839,0.00019535582,0.000017607663],"category_scores_gemma":[0.00006788353,0.00022986316,0.00005411704,0.00009889804,0.0007431792,0.00012458228,0.00014211626,0.00021368035,0.0000018426148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047195138,0.000061801235,0.001139478,0.000041034156,0.000036572466,0.000023987126,0.0002828521,3.7260585e-7,0.9932449,0.0030415028,0.00018862447,0.0014669425],"study_design_scores_gemma":[0.0012599931,0.00022177397,0.002221569,0.000021104592,0.00004006652,0.000057269997,0.000101779275,0.00006381482,0.9897693,0.0034542955,0.0026610836,0.00012799705],"about_ca_topic_score_codex":0.00003647427,"about_ca_topic_score_gemma":0.000020374058,"teacher_disagreement_score":0.0034756283,"about_ca_system_score_codex":0.000007830907,"about_ca_system_score_gemma":0.00002395542,"threshold_uncertainty_score":0.93735474},"labels":[],"label_agreement":null},{"id":"W4413903385","doi":"10.21203/rs.3.rs-7345742/v1","title":"Shared genetic basis for brain structure, insulin resistance and inflammation in schizophrenia: a colocalization study.","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute for Health and Care Research; Canadian Celiac Association; Department of Health and Social Care; Wellcome Trust","keywords":"Colocalization; Schizophrenia (object-oriented programming); Insulin resistance; Neuroscience; Inflammation; Resistance (ecology); Insulin; Genetics; Medicine; Psychology; Biology; Internal medicine; Psychiatry","score_opus":0.04920426167619392,"score_gpt":0.3678936269707259,"score_spread":0.318689365294532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413903385","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891361,0.00066665496,0.0007508568,0.0015188811,0.00013043544,0.006531151,0.00088137697,0.000081910446,0.00030265565],"genre_scores_gemma":[0.9972369,0.00017737178,0.0008410348,0.00008305395,0.00008457472,0.0009647822,0.00007871019,0.00002887718,0.00050468533],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99598193,0.001167294,0.00047095414,0.0011119748,0.00079313264,0.00047470786],"domain_scores_gemma":[0.9973133,0.0016421227,0.00011873276,0.00055557705,0.00027293764,0.00009732818],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008350241,0.00025773447,0.00034429342,0.00097508216,0.00028132895,0.00033417522,0.0005287617,0.00031520482,0.00003758412],"category_scores_gemma":[0.009094133,0.00026730486,0.000060070102,0.0011952874,0.00017339372,0.000119290286,0.00074717886,0.0008012265,0.000002871276],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.036138184,0.005512081,0.06945136,0.07727266,0.00040898734,0.0006930639,0.059741404,0.04049851,0.25021175,0.078644246,0.040307775,0.34111997],"study_design_scores_gemma":[0.01717463,0.0012572483,0.7072368,0.005621571,0.000038698716,0.0000036626286,0.0039483863,0.041006036,0.05782227,0.15733573,0.0066375225,0.0019174473],"about_ca_topic_score_codex":0.000093334136,"about_ca_topic_score_gemma":0.00417861,"teacher_disagreement_score":0.63778543,"about_ca_system_score_codex":0.00023586079,"about_ca_system_score_gemma":0.0005458061,"threshold_uncertainty_score":0.9999779},"labels":[],"label_agreement":null},{"id":"W4413916580","doi":"10.1503/jpn.240038","title":"The amino acid metabolism pathway of peripheral T lymphocytes and ketamine-induced schizophrenia-like phenotype","year":2023,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Phenotype; Schizophrenia (object-oriented programming); Peripheral; Ketamine; Metabolism; Biology; Neuroscience; Medicine; Genetics; Endocrinology; Internal medicine; Psychiatry; Gene","score_opus":0.02261824062659937,"score_gpt":0.2570269289477693,"score_spread":0.23440868832116993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413916580","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934707,0.0014615511,0.0000245202,0.0016720268,0.003106859,0.0000900671,0.0000068557115,0.00002401946,0.00014335156],"genre_scores_gemma":[0.99690694,0.0017442879,0.00015556459,0.00086413504,0.00015654005,0.0000017028401,7.172167e-8,0.000012932087,0.00015781914],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983079,0.0001592462,0.00043214718,0.00030738598,0.0004689055,0.0003244427],"domain_scores_gemma":[0.9989678,0.0002205366,0.0003936052,0.00020833116,0.000050422877,0.00015927175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046298947,0.00017135394,0.00024657953,0.00016002693,0.0004924512,0.00013992377,0.0005008604,0.000050151488,0.000004220646],"category_scores_gemma":[0.0005334076,0.000109614724,0.000097741424,0.00083953777,0.00055147754,0.00039433726,0.00012108149,0.00022886792,0.0000020823118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020617415,0.000059892234,0.00077812176,0.00002268175,0.0000027451906,0.000014075511,0.0002054227,0.000011100068,0.9847648,0.0052449247,0.00021368999,0.008476336],"study_design_scores_gemma":[0.0051927078,0.0016480322,0.33503747,0.00013333945,0.00005056129,0.000983886,0.001233123,0.0018665682,0.62970906,0.011058363,0.012448286,0.0006386161],"about_ca_topic_score_codex":0.000002603672,"about_ca_topic_score_gemma":0.000007973732,"teacher_disagreement_score":0.3550558,"about_ca_system_score_codex":0.000006774175,"about_ca_system_score_gemma":0.00020912738,"threshold_uncertainty_score":0.44699585},"labels":[],"label_agreement":null},{"id":"W4413920634","doi":"10.22215/cujs.v5i1.5284","title":"Depressive Symptom Heterogeneity and Inflammation: The Moderating Role of Early-Life Trauma","year":2025,"lang":"en","type":"article","venue":"Carleton undergraduate journal of science.","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Depressive symptoms; Psychology; Inflammation; Clinical psychology; Medicine; Psychiatry; Internal medicine; Anxiety","score_opus":0.017185013901371463,"score_gpt":0.26791097009957265,"score_spread":0.2507259561982012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413920634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930112,0.0005010723,0.0006912062,0.003108679,0.0002176915,0.00012527127,0.0000017940627,0.000009772211,0.0023333617],"genre_scores_gemma":[0.9992898,0.000114269926,0.00012676982,0.00037638895,0.000048560232,0.000001890404,5.043241e-8,0.0000051992497,0.000037032616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983286,0.00012269607,0.00047582685,0.0002287951,0.0005994951,0.00024456813],"domain_scores_gemma":[0.99869025,0.00030889906,0.00045579745,0.0002009788,0.00021976134,0.00012428752],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057888747,0.00012490364,0.0002166002,0.00026193046,0.00052651943,0.00020592033,0.0006111737,0.0000399963,0.0000031617908],"category_scores_gemma":[0.0009445875,0.00008284244,0.00009381614,0.00078454416,0.0015329943,0.00063275185,0.00012586745,0.00021749755,7.8556025e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045015506,0.000029723287,0.0034019493,0.000018931827,0.000015594967,0.000006229005,0.0010800111,0.0014294392,0.9681438,0.013766043,0.00007551599,0.011987738],"study_design_scores_gemma":[0.00069390965,0.00011285887,0.019954696,0.0000896012,0.000019497773,0.000060653983,0.0010480115,0.003661659,0.9543602,0.019767283,0.0001247442,0.00010691418],"about_ca_topic_score_codex":0.000010969663,"about_ca_topic_score_gemma":0.000007689489,"teacher_disagreement_score":0.016552746,"about_ca_system_score_codex":0.000039741484,"about_ca_system_score_gemma":0.00036428735,"threshold_uncertainty_score":0.5648382},"labels":[],"label_agreement":null},{"id":"W4413971114","doi":"10.1016/j.ibneur.2025.08.011","title":"Research hotspots and trends in the interaction mechanisms of neuroinflammation and sleep disorders: A bibliometric analysis based on WOS","year":2025,"lang":"en","type":"article","venue":"IBRO Neuroscience Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Dalian Medical University; Health Commission of Guizhou Province","keywords":"Bibliometrics; Data science; Neuroinflammation; Geography; Computer science; Library science; Medicine","score_opus":0.047011534839032844,"score_gpt":0.3601966936049759,"score_spread":0.31318515876594305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413971114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994054,0.000025434541,0.0011799346,0.001394638,0.00017802558,0.00026564012,0.0000021199457,0.000027203045,0.002872989],"genre_scores_gemma":[0.99937797,0.000068065085,0.000027033853,0.0004215933,0.0000043766076,0.000028054848,8.5554757e-7,0.000006143257,0.00006590482],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99720395,0.00049370463,0.00039552583,0.00075551466,0.00084469316,0.00030661759],"domain_scores_gemma":[0.9983018,0.00094193744,0.0001887205,0.00047270054,0.000040797975,0.00005406725],"candidate_categories":["bibliometrics"],"consensus_categories":["bibliometrics"],"category_scores_codex":[0.0014113814,0.00013540797,0.0001925322,0.056337006,0.00023018564,0.00021838513,0.00024053738,0.000050310806,0.000009140731],"category_scores_gemma":[0.0023316513,0.00010225031,0.00006760436,0.16106251,0.00034798658,0.0003487922,0.00009415209,0.00027294853,3.4316653e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014883459,0.0006217465,0.018920958,0.000076874945,0.0000056690455,0.00025254933,0.00043189715,0.0051981704,0.8098236,0.0040116287,0.00010175266,0.16040637],"study_design_scores_gemma":[0.00029489447,0.00032121976,0.8700015,0.000032319458,0.00002495896,0.00003578133,0.00020098196,0.06927172,0.054078642,0.005463553,0.00013932168,0.00013509748],"about_ca_topic_score_codex":0.0000769956,"about_ca_topic_score_gemma":0.00006494878,"teacher_disagreement_score":0.85108054,"about_ca_system_score_codex":0.000019558252,"about_ca_system_score_gemma":0.00003458197,"threshold_uncertainty_score":0.95435864},"labels":[],"label_agreement":null},{"id":"W4413979613","doi":"10.1139/jpn.0402","title":"The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-α-induced depression","year":2004,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Indoleamine 2,3-dioxygenase; Pathophysiology; Depression (economics); Interferon; Psychology; Immunology; Medicine; Biology; Internal medicine; Tryptophan; Genetics","score_opus":0.014961220492763536,"score_gpt":0.2600429496920287,"score_spread":0.24508172919926513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413979613","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997807,0.00042429788,0.000019570623,0.0007369395,0.0007786417,0.000091620335,0.0000022739735,0.0000021149692,0.00013754211],"genre_scores_gemma":[0.9989991,0.00023965813,0.000044237102,0.00066718046,0.00004001065,9.833278e-7,1.5075374e-8,0.0000044190338,0.0000043891578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869984,0.00021239337,0.0004285164,0.000176632,0.00030666537,0.00017595346],"domain_scores_gemma":[0.9990905,0.00014943651,0.00046802824,0.00021790546,0.000028212215,0.000045934758],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003328844,0.000096771706,0.00016644655,0.000094277246,0.00013343521,0.000018015526,0.0007336909,0.00004327409,0.0000011370662],"category_scores_gemma":[0.00046037254,0.00005026868,0.00009109054,0.0004840697,0.00033924668,0.00017181855,0.000088680536,0.00029209472,2.6668397e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014612962,0.0002267381,0.0019427896,0.0000108748145,4.175892e-7,0.0000033472943,0.0002154319,0.00010390145,0.99433434,0.001313417,0.000009353562,0.0016932373],"study_design_scores_gemma":[0.0008855681,0.0008023168,0.09832725,0.000109430475,0.000002188058,0.00011309248,0.00046070406,0.000045777462,0.8814652,0.017641423,0.000081362814,0.00006568376],"about_ca_topic_score_codex":0.0000062537306,"about_ca_topic_score_gemma":0.000017655226,"teacher_disagreement_score":0.11286916,"about_ca_system_score_codex":0.0000064761975,"about_ca_system_score_gemma":0.00012525747,"threshold_uncertainty_score":0.20498973},"labels":[],"label_agreement":null},{"id":"W4413981320","doi":"10.1139/jpn.090083","title":"Oxidative damage to RNA but not DNA in the hippocampus of patients with major mental illness","year":2010,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Hippocampus; Mental illness; RNA; Neuroscience; Oxidative damage; Medicine; Oxidative stress; Bioinformatics; Psychiatry; Biology; Internal medicine; Genetics; Gene; Mental health","score_opus":0.010657385335156363,"score_gpt":0.24943780785780975,"score_spread":0.23878042252265338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413981320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958498,0.0000063235957,0.000035316578,0.0022219247,0.001489514,0.00019863305,0.000020691481,0.0000035988808,0.00017418645],"genre_scores_gemma":[0.9961527,0.0000110237515,0.00028564793,0.0034826011,0.00004335686,0.0000018902365,1.1497644e-7,0.0000067848805,0.000015874843],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99858356,0.00012059869,0.00030158102,0.00024333256,0.0005372993,0.0002136559],"domain_scores_gemma":[0.9992433,0.00012300226,0.00029829112,0.00018199014,0.000042443076,0.00011095238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033437007,0.00012615114,0.00015893423,0.00016731165,0.00017408052,0.00006104101,0.000636372,0.000031697193,0.000010586568],"category_scores_gemma":[0.00030613985,0.000074114694,0.000042909865,0.0005903347,0.0003857794,0.0004006542,0.000058558755,0.00036792035,0.0000011690545],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038272218,0.0005334508,0.027525233,0.000014248588,9.2813576e-7,0.000011603433,0.0011031572,0.000007937178,0.96753794,0.00092579133,0.00016847257,0.0017884889],"study_design_scores_gemma":[0.001746881,0.0013413578,0.7752708,0.00004666995,0.0000074667732,0.00007030583,0.0008086005,0.000025933276,0.21885626,0.0012124802,0.00042546928,0.0001877604],"about_ca_topic_score_codex":0.0000038694448,"about_ca_topic_score_gemma":0.000045685152,"teacher_disagreement_score":0.7486817,"about_ca_system_score_codex":0.000004761177,"about_ca_system_score_gemma":0.00008314143,"threshold_uncertainty_score":0.30223095},"labels":[],"label_agreement":null},{"id":"W4413981355","doi":"10.1139/jpn.0806","title":"A major single nucleotide polymorphism of the <i>PDLIM5</i> gene associated with recurrent major depressive disorder","year":2008,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Single-nucleotide polymorphism; Genetics; Gene; Polymorphism (computer science); Major depressive disorder; Medicine; Biology; Genotype; Psychiatry","score_opus":0.019344042253802103,"score_gpt":0.23255619649399167,"score_spread":0.21321215424018958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413981355","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946171,0.0007107004,0.0001234342,0.0024369545,0.0016963264,0.00015427191,0.000018502311,0.000013335885,0.00022934182],"genre_scores_gemma":[0.99752694,0.00023097548,0.00015979735,0.0018359355,0.00008015864,0.000001700104,9.824429e-8,0.000016591724,0.00014777212],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980677,0.0001989571,0.0004426344,0.0003269476,0.00064981903,0.00031396883],"domain_scores_gemma":[0.9985478,0.00014648169,0.00083957484,0.00024576197,0.000074151576,0.00014626372],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016294575,0.00018919722,0.00026013626,0.00011365903,0.0005156551,0.000039189938,0.00063424645,0.000051014806,0.000009670585],"category_scores_gemma":[0.0005093847,0.00011453895,0.00013944479,0.00078373536,0.00090530014,0.0003490823,0.00010138141,0.0003351726,8.255351e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002643586,0.0011463196,0.054373406,0.00002004571,0.000008210332,0.00005565176,0.0003183168,0.000060801132,0.94213974,0.00031906023,0.0008517824,0.0004422901],"study_design_scores_gemma":[0.0055519044,0.0028063012,0.582253,0.00042783323,0.00009433996,0.0029573175,0.0001897641,0.00018562416,0.40222692,0.0014852079,0.0012627267,0.0005590903],"about_ca_topic_score_codex":0.0000056999625,"about_ca_topic_score_gemma":0.000026817295,"teacher_disagreement_score":0.5399128,"about_ca_system_score_codex":0.000014794914,"about_ca_system_score_gemma":0.00020824347,"threshold_uncertainty_score":0.46707627},"labels":[],"label_agreement":null},{"id":"W4414005020","doi":"10.1139/jpn.0926","title":"Positive association of the pericentrin (<i>PCNT</i>) gene with major depressive disorder in the Japanese population","year":2009,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Association (psychology); Biology; Major depressive disorder; Gene; Genetics; Evolutionary biology; Psychology; Neuroscience; Psychotherapist","score_opus":0.007516956588405877,"score_gpt":0.23923188568494164,"score_spread":0.23171492909653577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414005020","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99112767,0.00014725959,0.000039316823,0.008025153,0.00036349715,0.00014982803,0.000004207835,0.0000027862975,0.00014026456],"genre_scores_gemma":[0.99670726,0.00007265814,0.000051867843,0.0030828314,0.000044482636,8.073447e-7,8.5313076e-8,0.0000032640103,0.000036726527],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986415,0.0002635729,0.0002597526,0.00016518081,0.0005055712,0.00016444722],"domain_scores_gemma":[0.9991237,0.0001397989,0.00054003636,0.00012428821,0.0000380927,0.000034062738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029879538,0.00009182456,0.00012201107,0.00007120747,0.0002004344,0.000054212334,0.00037325177,0.000033469452,0.0000018815463],"category_scores_gemma":[0.0003353547,0.000046530404,0.00005646737,0.00065832207,0.00009337246,0.0003152256,0.000018827097,0.00023523287,1.5276053e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040374952,0.0008569779,0.7265405,0.00001804974,0.000003456097,0.00001900145,0.002737851,0.0010953603,0.2646428,0.0022082312,0.00019078751,0.001283227],"study_design_scores_gemma":[0.00083872554,0.00033747515,0.9900352,0.000036060286,0.000012027848,0.00014465334,0.00031479044,0.000094777075,0.007266462,0.0008271572,0.000027819067,0.00006484645],"about_ca_topic_score_codex":0.000013143091,"about_ca_topic_score_gemma":0.000039800852,"teacher_disagreement_score":0.2634947,"about_ca_system_score_codex":0.000016978393,"about_ca_system_score_gemma":0.000049677925,"threshold_uncertainty_score":0.18974547},"labels":[],"label_agreement":null},{"id":"W4414032967","doi":"10.1139/jpn.0721","title":"<scp>l</scp>-Tyrosine to alleviate the effects of stress?","year":2007,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Stress (linguistics); Tyrosine; Psychology; Biology; Biochemistry; Linguistics; Philosophy","score_opus":0.012988131688266381,"score_gpt":0.2647099453515634,"score_spread":0.251721813663297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414032967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932259,0.00049571844,0.0012767704,0.0012717505,0.0029482385,0.00015979484,0.0000034654993,0.0000103143175,0.00060806563],"genre_scores_gemma":[0.9943737,0.00033750202,0.00028969324,0.0046040425,0.00015880373,7.1056604e-7,2.207188e-8,0.000009535782,0.00022598243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984142,0.000098999044,0.00041715117,0.00024447183,0.0004978295,0.00032733104],"domain_scores_gemma":[0.99813527,0.0010115786,0.00038555946,0.00020470002,0.00004815723,0.00021472706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005809472,0.00013857505,0.00019233036,0.00017566778,0.00021128089,0.00006121338,0.00062561093,0.000038826263,0.0000024010876],"category_scores_gemma":[0.0027912906,0.00008712371,0.00009836548,0.00072783715,0.0003258696,0.0002469726,0.00008965748,0.00025872688,0.0000032936973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004320489,0.00026994775,0.0066380906,0.000088814326,0.0000018798472,0.000034613087,0.000446408,0.000053897955,0.98506993,0.0031410072,0.0028824625,0.0013297412],"study_design_scores_gemma":[0.0009065376,0.0017965742,0.22425158,0.00021012464,0.000017616157,0.00031170648,0.0003875681,0.000036400677,0.75922287,0.0017597578,0.011005308,0.00009396003],"about_ca_topic_score_codex":0.0000017991712,"about_ca_topic_score_gemma":0.000008131069,"teacher_disagreement_score":0.22584707,"about_ca_system_score_codex":0.00000567768,"about_ca_system_score_gemma":0.00007030791,"threshold_uncertainty_score":0.3552802},"labels":[],"label_agreement":null},{"id":"W4414057641","doi":"10.1016/j.biopsych.2025.08.020","title":"RNA in Plasma Extracellular Vesicles of Adolescent Rhesus Macaques Reveals Immune, Bioenergetic, and Microbial Imprints of Early-Life Adversity: An Exploratory Analysis","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Institute on Drug Abuse; Saban Research Institute; National Institutes of Health; National Institute of Mental Health; Canadian Institute for Advanced Research; Emory University; Children's Hospital Los Angeles","keywords":"RNA; Immune system; Extracellular vesicles; Microbiome; Extracellular; Exploratory analysis","score_opus":0.028493903521834917,"score_gpt":0.2632486730271782,"score_spread":0.23475476950534327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414057641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976868,0.0014516647,0.00007465231,0.00020303213,0.00020995164,0.00017599523,0.000035337343,0.000032349206,0.00013022096],"genre_scores_gemma":[0.99873435,0.0004406835,0.0005162564,0.0002555949,0.00001854529,0.0000039884026,0.000004481602,0.0000056140752,0.000020455838],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9982927,0.00033098264,0.0005200707,0.0004974437,0.00011454685,0.00024428268],"domain_scores_gemma":[0.9992959,0.00009044408,0.00020195391,0.00029656995,0.000025813028,0.00008932304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022559447,0.00017616394,0.00045025063,0.00034264574,0.00005438721,0.000012883128,0.00034497204,0.00018709622,0.00003309601],"category_scores_gemma":[0.00017042615,0.00014653355,0.0001663723,0.0007956651,0.00039839407,0.00008016631,0.00015531674,0.00016013997,0.000002425421],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003125364,0.000500886,0.22058338,0.000060786468,0.00003571142,0.0000023023103,0.00009104116,0.000012626353,0.775259,0.002101202,0.00005095058,0.000989579],"study_design_scores_gemma":[0.0010183828,0.00023111803,0.7920019,0.000076921024,0.00004805471,4.7620136e-7,0.00055677356,0.00006838867,0.20447448,0.0012731267,0.00005200506,0.00019837366],"about_ca_topic_score_codex":0.000039577302,"about_ca_topic_score_gemma":0.00004149046,"teacher_disagreement_score":0.5714185,"about_ca_system_score_codex":0.000014538783,"about_ca_system_score_gemma":0.000060154307,"threshold_uncertainty_score":0.5975465},"labels":[],"label_agreement":null},{"id":"W4414065598","doi":"10.1101/2025.09.07.674758","title":"Neuronal and Astrocytic Activity Changes Induced by Acute and Chronic Stress","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mental Health Research Canada","funders":"Canadian Institutes of Health Research; Campbell Family Mental Health Research Institute","keywords":"Chronic stress; Premovement neuronal activity; Astrocyte; Prefrontal cortex; Mechanism (biology); Central nervous system; Depression (economics); Neural activity","score_opus":0.017863196538468903,"score_gpt":0.2376533678851316,"score_spread":0.2197901713466627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414065598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959699,0.0007132431,0.00010431463,0.00075079314,0.0005824678,0.000615297,0.0009795002,0.00027243298,0.000012048178],"genre_scores_gemma":[0.99805355,0.001030146,0.00009411946,0.0004783825,0.00014928245,0.00011964034,1.8385344e-7,0.000054943917,0.000019765212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972951,0.00019106099,0.00019522637,0.001417543,0.00032379755,0.0005772934],"domain_scores_gemma":[0.9986026,0.0001603354,0.00023643361,0.0006825919,0.000062151536,0.00025584133],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013932162,0.0005585015,0.00048518792,0.00022926478,0.00022974948,0.00030769434,0.00045939197,0.0003993237,0.00001641809],"category_scores_gemma":[0.00020622372,0.00060276594,0.00006089764,0.00034230502,0.000249573,0.00016401397,0.0009844603,0.00088960136,0.000005766333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037008445,0.00007826365,0.00031490522,0.0003702044,0.000039957504,0.000017102722,0.0000065640766,0.0000021742583,0.9987793,0.0001598602,0.00015709209,0.00003758472],"study_design_scores_gemma":[0.0007110281,0.000116528165,0.029928936,0.00022765984,0.000059527047,2.2865114e-8,0.000001214509,0.00034286114,0.9669137,0.000001520477,0.0011637738,0.0005332114],"about_ca_topic_score_codex":0.000020847367,"about_ca_topic_score_gemma":0.000010789519,"teacher_disagreement_score":0.031865567,"about_ca_system_score_codex":0.00016033105,"about_ca_system_score_gemma":0.00045632204,"threshold_uncertainty_score":0.9996424},"labels":[],"label_agreement":null},{"id":"W4414082191","doi":"10.1002/brb3.70742","title":"Shared Genetic Architecture Among Severe Mental Disorders: A System Biology Approach Based on Protein–Protein Interaction","year":2025,"lang":"en","type":"article","venue":"Brain and Behavior","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Center for Clinical and Translational Research; Pontificia Universidad Javeriana; Universidad Simón Bolívar; Universidad El Bosque","keywords":"Systems biology; Genetic architecture; Precision medicine; Architecture; Mental model; Biological network; MEDLINE","score_opus":0.013313885958769176,"score_gpt":0.2557963915084829,"score_spread":0.2424825055497137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414082191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99223316,0.000029917215,0.0013271433,0.00080404885,0.00015859737,0.0020965675,0.00006568499,0.00017965607,0.003105256],"genre_scores_gemma":[0.99691844,8.1922997e-7,0.0006860326,0.0006969528,0.000025784437,0.00077002536,0.000027073665,0.000020095418,0.0008547501],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99851376,0.0002203969,0.00021319096,0.0006360976,0.00013825555,0.000278284],"domain_scores_gemma":[0.9995056,0.0000679246,0.000076702396,0.0002627836,0.000012391901,0.00007462251],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007684356,0.00023471942,0.00019049658,0.0002216293,0.00021195199,0.00009513106,0.00020781404,0.00014085327,0.000039626357],"category_scores_gemma":[0.000118627184,0.0001986501,0.00008451999,0.0002780587,0.00017119973,0.000071672795,0.00007052989,0.00025157345,0.000008928068],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040204191,0.0014439216,0.0045431554,0.00055088574,0.0000121014245,0.000022654127,0.00045425454,0.00008562073,0.8749864,0.002318173,0.0007228391,0.114457935],"study_design_scores_gemma":[0.026056709,0.004325642,0.44380438,0.003886857,0.0002753088,0.00021166829,0.008314275,0.044617694,0.44267234,0.002054304,0.019005997,0.0047748056],"about_ca_topic_score_codex":0.00005541433,"about_ca_topic_score_gemma":0.000034924913,"teacher_disagreement_score":0.43926123,"about_ca_system_score_codex":0.00005499219,"about_ca_system_score_gemma":0.000036769936,"threshold_uncertainty_score":0.81007165},"labels":[],"label_agreement":null},{"id":"W4414180648","doi":"10.1192/j.eurpsy.2025.759","title":"Immune/inflammatory parameters as potential predictors of high-lethality suicidal behavior in individuals with/without psychiatric conditions: a retrospective single-center study","year":2025,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Suicide attempt; Odds ratio; Retrospective cohort study; Suicide prevention; Poison control; Suicide methods; Injury prevention; Observational study; Emergency department","score_opus":0.011128993798900769,"score_gpt":0.2592998018588422,"score_spread":0.24817080805994146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414180648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898267,0.00012440562,0.00003877501,0.00024877785,0.002201101,0.0016995698,0.00013760194,0.00017385687,0.0055492334],"genre_scores_gemma":[0.9987136,0.0000049896585,0.00037858554,0.00047331644,0.00008151735,0.00007609229,0.000016240263,0.00006340597,0.00019221683],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99595225,0.0011438341,0.00089918554,0.0009351222,0.00059134065,0.00047826543],"domain_scores_gemma":[0.99857396,0.00008018517,0.0004303769,0.0007509985,0.000059764778,0.0001046925],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00051324605,0.00039309287,0.0004758019,0.00068949955,0.00019781526,0.00009366461,0.00069235737,0.00008494549,0.000080284626],"category_scores_gemma":[0.00018507968,0.00036390108,0.00018207496,0.0011565336,0.0003981242,0.0002522604,0.00018690585,0.00053525006,0.000053394997],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002690327,0.0046748486,0.988654,0.00004291577,0.00006735083,0.000045907727,0.0009197115,0.000037861326,0.003806395,0.0010456095,0.0003551471,0.00008118072],"study_design_scores_gemma":[0.005871086,0.0011131541,0.9881599,0.00010100646,0.00010162463,0.000023062681,0.0023173396,0.0000025502395,0.0012765749,0.0006558926,0.00003420591,0.00034359927],"about_ca_topic_score_codex":0.000083921055,"about_ca_topic_score_gemma":0.00012989866,"teacher_disagreement_score":0.008886958,"about_ca_system_score_codex":0.00008802963,"about_ca_system_score_gemma":0.0001937729,"threshold_uncertainty_score":0.99988127},"labels":[],"label_agreement":null},{"id":"W4414207381","doi":"10.1192/j.eurpsy.2025.1164","title":"Oxidative Stress and Cortical Thickness in the Psychosis Spectrum: Investigating Glutathione Metabolism and Antioxidant Defenses in Youth","year":2025,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Mennonite University","funders":"Instituto de Salud Carlos III","keywords":"Glutathione; Psychosis; Oxidative stress; Insula; Antioxidant; Antioxidant capacity","score_opus":0.021244887266181685,"score_gpt":0.26329663616600985,"score_spread":0.24205174889982817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414207381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9854509,0.0015806288,0.00006323558,0.0039921124,0.00034804025,0.00024889188,0.00002261707,0.000041985197,0.008251575],"genre_scores_gemma":[0.9942721,0.000167134,0.00036922048,0.0050875964,0.00004936868,0.000004503253,0.0000013227137,0.000017930028,0.00003080435],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976066,0.0010824575,0.00032402188,0.0005196799,0.00017669013,0.00029056202],"domain_scores_gemma":[0.9993444,0.00026375396,0.00007781169,0.00024569136,0.000007630673,0.000060716506],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052395114,0.00019060071,0.00019106679,0.00020146919,0.00017738716,0.0001327535,0.000279761,0.000050921426,0.000005427548],"category_scores_gemma":[0.00044991684,0.00014321032,0.000031455806,0.0007410874,0.0003835252,0.00013558952,0.000114095295,0.00063568173,0.0000062927943],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027241767,0.0013820606,0.5679874,0.000422264,0.00003268651,0.00012832669,0.07991065,0.00004541047,0.066816725,0.27709055,0.00063480873,0.005276737],"study_design_scores_gemma":[0.0013519044,0.000041069296,0.97305465,0.00046041145,0.000017704508,0.00001494665,0.0123805525,0.00006510001,0.0017040336,0.01061601,0.00006573673,0.00022787316],"about_ca_topic_score_codex":0.000038182858,"about_ca_topic_score_gemma":0.00025903425,"teacher_disagreement_score":0.4050673,"about_ca_system_score_codex":0.0000064225196,"about_ca_system_score_gemma":0.00003410329,"threshold_uncertainty_score":0.58399475},"labels":[],"label_agreement":null},{"id":"W4414254099","doi":"10.3389/fpsyt.2025.1651246","title":"Associations between suicide attempts and clinical, metabolic, and inflammatory markers in Chinese patients with long-term schizophrenia","year":2025,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Proinflammatory cytokine; Schizophrenia (object-oriented programming); Psychological intervention; Context (archaeology); Inflammation; Depression (economics); Suicide Risk; Major depressive disorder","score_opus":0.008992316668047444,"score_gpt":0.28158506812414225,"score_spread":0.2725927514560948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414254099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952718,0.001012926,0.000115597184,0.0004994285,0.0020691196,0.0004773665,0.000055164095,0.000041326235,0.00045729213],"genre_scores_gemma":[0.9970542,0.0003076847,0.0018497779,0.0006039625,0.000058160073,0.000015424299,0.0000168425,0.000020702564,0.0000732321],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981717,0.0002396341,0.0005251574,0.0005548234,0.0001919183,0.00031675192],"domain_scores_gemma":[0.9992748,0.0001877279,0.0001666228,0.000255787,0.000017638191,0.00009746145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025652032,0.00022168786,0.0004374777,0.00044608756,0.000118777236,0.000065718996,0.00021847792,0.00015745252,0.0000043438235],"category_scores_gemma":[0.00032632606,0.00019470791,0.000051538715,0.00070313824,0.00026639565,0.00025628522,0.000096747695,0.00038516254,0.0000017709656],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018059685,0.00014430887,0.99053305,0.000027655335,0.000034447825,0.000002290432,0.000051075906,0.0000011248713,0.000004417773,0.00015859609,0.0018245011,0.0070379316],"study_design_scores_gemma":[0.0045771585,0.00004209683,0.9932561,0.000103025275,0.000023973058,2.3392307e-7,0.000035453646,0.000017955093,0.000007471656,0.0016863544,0.00004794951,0.00020223595],"about_ca_topic_score_codex":0.000024438159,"about_ca_topic_score_gemma":0.0006422199,"teacher_disagreement_score":0.006835696,"about_ca_system_score_codex":0.00003265037,"about_ca_system_score_gemma":0.00012572027,"threshold_uncertainty_score":0.7939958},"labels":[],"label_agreement":null},{"id":"W4414280009","doi":"10.1016/s2215-0366(25)00262-7","title":"Mortality from respiratory diseases in individuals with severe mental illness: a large-scale systematic review and meta-analysis of pooled and specific diagnoses","year":2025,"lang":"en","type":"review","venue":"The Lancet Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"Instituto de Salud Carlos III; European Commission","keywords":"Medical diagnosis; Respiratory system; MEDLINE; Mental health; Epidemiology; Respiratory disease","score_opus":0.06589996849830865,"score_gpt":0.33914892052507517,"score_spread":0.2732489520267665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414280009","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009145266,0.98969924,0.0000017924004,0.00033748572,0.00007262037,0.002507605,0.006325862,0.00002955201,0.000111306545],"genre_scores_gemma":[0.00046734983,0.9963491,0.000035216035,0.002469467,0.000035708104,0.00051333633,0.000066540946,0.000022480992,0.0000408178],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99608946,0.0015595459,0.0009286292,0.00075025443,0.0003928182,0.00027927573],"domain_scores_gemma":[0.99694306,0.0010598099,0.0007791877,0.0011326469,0.000015337275,0.00006997253],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00061141665,0.0004739895,0.006759261,0.0002578297,0.00011058511,0.000068775684,0.0006312961,0.00010563917,0.00011993062],"category_scores_gemma":[0.00019696653,0.00024574445,0.00073422637,0.0015039503,0.00020914583,0.00009590959,0.00019134302,0.00027843667,0.0000027352332],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012591812,0.00035716867,0.0038486703,0.9529829,0.03857113,0.000006215727,0.0003276247,5.871052e-7,2.553405e-7,0.0005968659,0.0025614183,0.00073454226],"study_design_scores_gemma":[0.000764789,0.00004189325,0.003699961,0.07893256,0.89496195,0.0000060630305,0.000371991,0.0000012509299,8.976212e-7,0.0004731349,0.020032313,0.00071320945],"about_ca_topic_score_codex":0.000017142678,"about_ca_topic_score_gemma":0.00028610753,"teacher_disagreement_score":0.8740504,"about_ca_system_score_codex":0.000017835242,"about_ca_system_score_gemma":0.00012546439,"threshold_uncertainty_score":0.99999946},"labels":[],"label_agreement":null},{"id":"W4414391852","doi":"10.1002/ajmg.b.33060","title":"The Genetic Landscape of Kynurenine Predicts Neurovascular Pathology and Disrupted White Matter Integrity in Patients With Mood Disorders","year":2025,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Ministero della Salute","keywords":"Hyperintensity; Kynurenine; Bipolar disorder; White matter; Mood disorders; Mood; Major depressive disorder","score_opus":0.004299110739466791,"score_gpt":0.22562148495939993,"score_spread":0.22132237421993314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414391852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99352866,0.0010731955,0.00080679683,0.0034680692,0.0006536272,0.00028673964,0.000010259949,0.0000088994475,0.00016373383],"genre_scores_gemma":[0.991811,0.006373083,0.0006824057,0.0010148411,0.000060221213,0.000005392202,0.0000013448579,0.000033034605,0.000018693963],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9962323,0.0007208771,0.0009950121,0.00043472843,0.0011502642,0.0004668439],"domain_scores_gemma":[0.9980578,0.000455668,0.00061544054,0.0004714802,0.0001314408,0.00026817576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039744782,0.00029322857,0.00051990105,0.00033429905,0.00011100193,0.00004380948,0.0008852058,0.000106069456,0.00002858178],"category_scores_gemma":[0.00049814256,0.00019426298,0.000120915174,0.0013304215,0.0012113419,0.000029944906,0.00020988929,0.00081578246,0.0000019720117],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029225159,0.00042906523,0.9587872,0.000031741467,0.000028272272,0.000022469781,0.00013391275,0.00037502905,0.00007064301,0.000022770078,0.00048761387,0.039319027],"study_design_scores_gemma":[0.0031210126,0.0020124514,0.99230707,0.000052351603,0.000074046,0.00006517558,0.00013078832,0.00076456356,0.00008210738,0.00019968061,0.0010144913,0.00017627691],"about_ca_topic_score_codex":0.000004238271,"about_ca_topic_score_gemma":0.00005291137,"teacher_disagreement_score":0.03914275,"about_ca_system_score_codex":0.00001027613,"about_ca_system_score_gemma":0.00024795532,"threshold_uncertainty_score":0.7921814},"labels":[],"label_agreement":null},{"id":"W4414483012","doi":"10.1016/j.psychres.2025.116742","title":"The cognitive metabolomic signatures in schizophrenia spectrum disorders: A systematic review","year":2025,"lang":"en","type":"review","venue":"Psychiatry Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; Physicians' Services Incorporated Foundation; Danish Diabetes Academy; Department of Psychiatry, University of Toronto; Centre for Addiction and Mental Health Foundation; University of Toronto; Weston Brain Institute","keywords":"Cognition; Schizophrenia (object-oriented programming); Metabolomics; Glutamate receptor; Cognitive impairment; Glutamine; Energy metabolism; Lipid metabolism","score_opus":0.06004491187877299,"score_gpt":0.41016059429225155,"score_spread":0.35011568241347857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414483012","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000014744847,0.9809453,0.0000033354715,0.0024514103,0.0008900915,0.009957212,0.000088313915,0.0000785783,0.005584295],"genre_scores_gemma":[0.000026823887,0.9937072,0.000013191221,0.00043525943,0.0001360275,0.0029582789,0.000012568791,0.0000747079,0.0026359858],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.98732936,0.007189439,0.0015294683,0.0013362699,0.0013277497,0.0012877103],"domain_scores_gemma":[0.9881313,0.0099808145,0.00043718453,0.0012463584,0.00005639214,0.00014796203],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0039929636,0.0006750365,0.002721928,0.0009984137,0.0007283534,0.0003393293,0.0026445014,0.00036593943,0.00010672642],"category_scores_gemma":[0.011193598,0.0004006336,0.0008888976,0.005167444,0.0005852296,0.00011943717,0.0005321409,0.0033255953,0.0005503244],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000419452,0.0001735847,8.2204446e-7,0.94316643,0.00007889755,0.000007731077,0.000016334972,6.555483e-8,2.0178321e-7,0.011189594,0.00534855,0.039975844],"study_design_scores_gemma":[0.00044876742,0.000070344366,0.000003070206,0.8630528,0.00044914646,0.000009574107,0.00009915629,0.0000037005,8.6838156e-7,0.008264478,0.12712754,0.00047057643],"about_ca_topic_score_codex":0.000026363736,"about_ca_topic_score_gemma":0.00063419534,"teacher_disagreement_score":0.121779,"about_ca_system_score_codex":0.00012612957,"about_ca_system_score_gemma":0.0019344745,"threshold_uncertainty_score":0.99984455},"labels":[],"label_agreement":null},{"id":"W4414681819","doi":"10.1016/j.brainres.2025.149977","title":"Recombinant IL-1β induces striatal dopamine depletion in aged rats: Involvement of histamine H1 receptors","year":2025,"lang":"en","type":"article","venue":"Brain Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Micropharma (Canada)","funders":"Ministry of Science and Higher Education of the Russian Federation","keywords":"Catalepsy; Dopamine; Histamine; Histaminergic; Neurochemical; Thioperamide; Striatum; Domperidone; Dopamine receptor D2","score_opus":0.08380990672433494,"score_gpt":0.3597075427065065,"score_spread":0.27589763598217154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414681819","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99193203,0.00011190892,0.000048043148,0.0038614762,0.0003848238,0.0007368567,0.00001782296,0.000038835657,0.0028682156],"genre_scores_gemma":[0.99277616,0.00018639893,0.00007234863,0.00024590184,0.000026453456,0.00008704151,0.00002046626,0.000016609989,0.006568602],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99624896,0.0013167658,0.00048702184,0.0005880797,0.0007810892,0.0005780904],"domain_scores_gemma":[0.99780124,0.0015199091,0.000084008476,0.00042115987,0.00008980987,0.0000838791],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002772428,0.00015514882,0.00025601845,0.00097018,0.00016222002,0.000054971537,0.0005958719,0.00011590876,0.00016908254],"category_scores_gemma":[0.0052540274,0.00014398234,0.00006465601,0.0023557658,0.00040508117,0.00015842331,0.00032200228,0.00053655234,0.000026683001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018691,0.0005814883,0.0021548439,0.00013833346,0.0000060930597,0.000018919876,0.000581507,0.0000067759756,0.95795816,0.0041902824,0.015884344,0.01829236],"study_design_scores_gemma":[0.0024275032,0.00042512742,0.033097614,0.00024402032,0.0000016996265,9.096432e-7,0.0023411456,0.0000877982,0.9439837,0.0024944295,0.014699736,0.00019637158],"about_ca_topic_score_codex":0.00052237604,"about_ca_topic_score_gemma":0.00077263877,"teacher_disagreement_score":0.03094277,"about_ca_system_score_codex":0.00025470924,"about_ca_system_score_gemma":0.00026769337,"threshold_uncertainty_score":0.6289941},"labels":[],"label_agreement":null},{"id":"W4414683681","doi":"10.47626/1516-4446-2025-4228","title":"Association between B-cell activating factor and future depressive symptoms in hemodialysis patients","year":2025,"lang":"en","type":"article","venue":"Brazilian Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Western University","funders":"","keywords":"Hemodialysis; B-cell activating factor; Depressive symptoms; Risk factor; Depression (economics)","score_opus":0.0059680552165723355,"score_gpt":0.24213915746044634,"score_spread":0.236171102243874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414683681","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99532413,0.0002425953,0.000057162357,0.0020645822,0.0010293472,0.00010286769,0.000015935382,0.000009587271,0.0011537869],"genre_scores_gemma":[0.9986588,0.0000615697,0.00026508793,0.0005336355,0.0003336184,0.0000011697064,0.0000010218756,0.000009931476,0.00013517159],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987117,0.00016210925,0.00043314398,0.00020086658,0.00028203137,0.00021016873],"domain_scores_gemma":[0.9989663,0.00023392779,0.00056099833,0.00010255696,0.00006017539,0.000076092205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012451832,0.00013216725,0.00024808195,0.00030627416,0.00010125691,0.000064095024,0.00021595192,0.00012596519,0.00002829426],"category_scores_gemma":[0.00030141554,0.00011842758,0.00010601811,0.00047206975,0.000024569115,0.00030293455,0.000036066896,0.00036555555,0.0000024245403],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003321674,0.00013663579,0.97134435,0.000030583433,0.000030311623,0.0000015132105,0.00025178777,0.0000043040955,0.002124179,0.000057869256,0.0009460826,0.025039166],"study_design_scores_gemma":[0.0027909135,0.00007634694,0.98474336,0.00008343791,0.00002395084,0.000001142544,0.0002115841,0.000009521892,0.00948271,0.0013752113,0.0010718604,0.00012997809],"about_ca_topic_score_codex":0.0000021342582,"about_ca_topic_score_gemma":0.000010378459,"teacher_disagreement_score":0.024909189,"about_ca_system_score_codex":0.00008152425,"about_ca_system_score_gemma":0.00011364417,"threshold_uncertainty_score":0.48293367},"labels":[],"label_agreement":null},{"id":"W4414754283","doi":"10.1128/mbio.02052-25","title":"Microbiota-derived aromatic amino acid decarboxylases: linking microbial fitness and host neurochemical communication","year":2025,"lang":"en","type":"review","venue":"mBio","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Innovation Cluster (Canada)","funders":"LEO Fondet; Institut Teknologi Sepuluh Nopember; Deutsche Forschungsgemeinschaft","keywords":"Monoamine neurotransmitter; Aromatic amino acids; Gut flora; Host (biology); Neurochemical; Immune system; Innate immune system; Microbiome; Bacteria; Amino acid","score_opus":0.03289401828313423,"score_gpt":0.29239024479446474,"score_spread":0.25949622651133053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414754283","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009800675,0.98804826,0.000027982118,0.00010777957,0.00029982827,0.0009437574,0.000086726744,0.00016201721,0.00052300625],"genre_scores_gemma":[0.0026053055,0.99591106,0.0002695747,0.0006029282,0.00005157964,0.00006606781,0.00012391043,0.000052830997,0.00031675005],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976917,0.00043724448,0.000586227,0.00076352485,0.00014040856,0.00038092866],"domain_scores_gemma":[0.99790126,0.0008328836,0.0003228617,0.00083386415,0.000018105142,0.00009104574],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010933244,0.0005038246,0.0010711065,0.00021879663,0.00025265498,0.00023085761,0.0009812289,0.0003946053,0.00002423662],"category_scores_gemma":[0.00054004806,0.000468475,0.00029074214,0.00052282104,0.0003745681,0.00009385173,0.0005969269,0.000610386,0.00006679324],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016358577,0.00026229085,0.0000033667338,0.030500757,0.000051402447,0.000034132474,0.00042010177,7.166006e-8,0.58994716,0.00009930022,0.0014828856,0.37718216],"study_design_scores_gemma":[0.0012268377,0.00007207931,0.000030406127,0.041161194,0.000559394,0.0002562874,0.00005573542,0.000014776614,0.118293606,0.00013763946,0.83659226,0.0015998053],"about_ca_topic_score_codex":0.000008291076,"about_ca_topic_score_gemma":0.000008102293,"teacher_disagreement_score":0.83510935,"about_ca_system_score_codex":0.00006471508,"about_ca_system_score_gemma":0.00018466325,"threshold_uncertainty_score":0.9997767},"labels":[],"label_agreement":null},{"id":"W4414791294","doi":"10.1016/j.pnpbp.2025.111509","title":"Astrocyte alterations and dysfunction in alcohol use disorder: A comprehensive scoping review of clinical postmortem and preclinical evidence","year":2025,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health","keywords":"Astrocyte; Glial fibrillary acidic protein; Alcohol use disorder; Neuroglia; Abstinence; Brain function","score_opus":0.14239740755519298,"score_gpt":0.46153343995612506,"score_spread":0.3191360324009321,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414791294","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.908197,0.08448003,0.00002212978,0.0049311924,0.0009691423,0.0013263578,0.00000878157,0.00003297528,0.000032427408],"genre_scores_gemma":[0.8290545,0.15870883,0.00045403637,0.011640882,0.000043152864,0.00008701311,0.0000023153589,0.0000053236695,0.0000039993147],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.996429,0.0011364694,0.001116617,0.0009261437,0.00009814334,0.00029357107],"domain_scores_gemma":[0.99633676,0.0030927483,0.00026155746,0.00016940723,0.000038988364,0.00010051079],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005219783,0.0002297648,0.0006404393,0.00016360168,0.000103708626,0.000030897696,0.00016310746,0.00023604151,0.000025671014],"category_scores_gemma":[0.0013622732,0.00018182003,0.00007802801,0.000461708,0.0011033182,0.00020999473,0.00016235128,0.0006416939,0.0000010211584],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012288857,0.0004142715,0.96534216,0.0017473421,0.000008973175,0.000010286957,0.000010712762,0.0000014378595,0.0002042962,0.00032599247,0.00010992906,0.030595725],"study_design_scores_gemma":[0.0034573374,0.0005989983,0.9861393,0.008658145,0.000021486596,0.000021027967,0.000014748095,0.00026426103,0.00002110571,0.0004930675,0.00015419451,0.0001563057],"about_ca_topic_score_codex":0.0000037852192,"about_ca_topic_score_gemma":0.000036363814,"teacher_disagreement_score":0.0791425,"about_ca_system_score_codex":0.0000041524168,"about_ca_system_score_gemma":0.0000784874,"threshold_uncertainty_score":0.7414406},"labels":[],"label_agreement":null},{"id":"W4414801940","doi":"10.1016/j.phymed.2025.157351","title":"The effectiveness and safety of Chinese herbal Jieyu Anshen Decoction monotherapy or in combination with Western medicine for mental disorders: A systematic review and meta-analysis of randomized controlled trials","year":2025,"lang":"en","type":"review","venue":"Phytomedicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Beijing University of Chinese Medicine","keywords":"Decoction; Western medicine; Randomized controlled trial; Alternative medicine; Therapeutic effect; Clinical trial; Phytotherapy","score_opus":0.04775989963449161,"score_gpt":0.3888254688691874,"score_spread":0.3410655692346958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414801940","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005867158,0.9677414,0.0008766289,0.000566076,0.00006164396,0.030585818,0.000074904,0.00001070705,0.000024183011],"genre_scores_gemma":[0.0061975643,0.98784286,0.000008896013,0.00014599298,0.000010750446,0.0056387736,0.000030302392,0.000019835172,0.00010504992],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.98872924,0.0071624173,0.0030883264,0.00044781915,0.00041373738,0.00015848102],"domain_scores_gemma":[0.9421361,0.054733895,0.002676536,0.00032569407,0.00008671941,0.000041035182],"candidate_categories":["metaresearch","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.01490657,0.00048484362,0.03063186,0.0006419938,0.0000724049,0.000013500866,0.0002118241,0.00009013975,0.000016413916],"category_scores_gemma":[0.01613066,0.00016373263,0.0016193981,0.0016065243,0.0005075239,0.00006885459,0.00002686595,0.00012095556,5.023931e-8],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.068722256,0.00017907198,0.000006722497,0.84748197,0.07543343,7.2924814e-7,0.00027518897,0.0000011534577,0.000008498947,0.00008718297,0.0000058694786,0.0077979257],"study_design_scores_gemma":[0.23711397,0.0006232275,0.000020390418,0.08950745,0.67180204,0.000005436612,0.00005803985,0.00010056133,0.0000038983485,0.00032073157,0.00024174675,0.00020253533],"about_ca_topic_score_codex":0.00002713036,"about_ca_topic_score_gemma":0.00014458956,"teacher_disagreement_score":0.7579745,"about_ca_system_score_codex":0.000036328493,"about_ca_system_score_gemma":0.000077749806,"threshold_uncertainty_score":0.99215686},"labels":[],"label_agreement":null},{"id":"W4415027464","doi":"10.1016/j.cyto.2025.157033","title":"Long-term storage stability of plasma TNF-α and IL-6 concentrations of psychiatric emergency patients: The Signature Biobank","year":2025,"lang":"en","type":"article","venue":"Cytokine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Douglas Mental Health University Institute; Institut Universitaire en Santé Mentale de Québec","funders":"Fonds de Recherche du Québec - Santé; Social Sciences and Humanities Research Council of Canada; Canadian Institutes of Health Research; Université de Montréal; Bell Canada Enterprises","keywords":"Biobank; Sample (material); Data quality; Signature (topology); Stability (learning theory); Cytokine","score_opus":0.013728711817655528,"score_gpt":0.2548787696812022,"score_spread":0.24115005786354668,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415027464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968373,0.00028757774,0.00016228955,0.00045291652,0.00044207805,0.00034277313,0.00020109049,0.000018846875,0.0012550844],"genre_scores_gemma":[0.9995461,0.00017364863,0.000021208112,0.00015783601,0.0000136355875,0.0000070647334,0.0000070269084,0.0000050744065,0.0000684178],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99911547,0.00008615065,0.00028034474,0.00023291679,0.00015036351,0.00013476217],"domain_scores_gemma":[0.99936205,0.00012685565,0.00013155087,0.00028217235,0.00006825661,0.00002912277],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007016279,0.00010163986,0.00013978532,0.00006318774,0.00009716441,0.000007664476,0.0002159457,0.00005606515,0.00013415595],"category_scores_gemma":[0.00031387524,0.00007222956,0.00005571514,0.0005988853,0.0002377347,0.000076026605,0.000060205475,0.000117078846,0.0000012590211],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024741451,0.0014172659,0.5036211,0.0005078191,0.000031958512,0.0000016039811,0.001105566,0.000029408986,0.4660071,0.012875307,0.005559729,0.0085957125],"study_design_scores_gemma":[0.0011619413,0.00015000424,0.7228816,0.000023108189,0.000025367546,3.9458115e-7,0.00009038116,0.00010832489,0.27393302,0.00066717714,0.00084097794,0.00011768226],"about_ca_topic_score_codex":0.0000060674356,"about_ca_topic_score_gemma":0.00002642519,"teacher_disagreement_score":0.21926053,"about_ca_system_score_codex":0.000011429876,"about_ca_system_score_gemma":0.00005255043,"threshold_uncertainty_score":0.2945436},"labels":[],"label_agreement":null},{"id":"W4415181674","doi":"10.1152/ajpheart.00395.2025","title":"Altered tryptophan metabolism and gut immune crosstalk in hypertensive middle-aged women","year":2025,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Health Services; Alberta Children's Hospital; Libin Cardiovascular Institute of Alberta; Alberta Health; University of Calgary","funders":"Bundesministerium für Bildung und Forschung; Canadian Institutes of Health Research; European Commission; University of Calgary","keywords":"Proinflammatory cytokine; Kynurenine; Kynurenine pathway; Metabolite; Gut flora; Microbiome; Metabolism; Metabolome; Tumor necrosis factor alpha","score_opus":0.014942498799555417,"score_gpt":0.2462211005009191,"score_spread":0.2312786017013637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415181674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99756134,0.0014143104,0.0000015822802,0.0003376702,0.00044486194,0.00014922915,0.000006700569,0.000019199906,0.000065139655],"genre_scores_gemma":[0.9951332,0.00037697636,0.000059325408,0.004233513,0.00012802554,0.000013368278,0.000001244278,0.000019086694,0.000035256766],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9975983,0.0005555864,0.00058885774,0.0005652174,0.000121790756,0.0005702379],"domain_scores_gemma":[0.99869746,0.0003903411,0.0003812725,0.000300551,0.00007471043,0.00015563627],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022689202,0.00029364313,0.001139396,0.00036769343,0.00017900315,0.000024095292,0.00027084173,0.00010717215,0.000037923506],"category_scores_gemma":[0.00022009223,0.00025105698,0.0001496179,0.000495536,0.0018911015,0.00019931063,0.00013585789,0.0005101053,0.0000049290684],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003853383,0.0001320968,0.00028494248,0.000033758675,0.000054453518,0.0000021498035,0.00096403423,0.000027461057,0.99662155,0.000371711,0.000074244155,0.0010482518],"study_design_scores_gemma":[0.0019740905,0.00040309562,0.9594966,0.00004546414,0.000017947063,0.00009710369,0.0019083443,0.000046786656,0.027169267,0.007584312,0.0010174722,0.00023949667],"about_ca_topic_score_codex":0.000032700995,"about_ca_topic_score_gemma":0.0000037728078,"teacher_disagreement_score":0.96945226,"about_ca_system_score_codex":0.000042269974,"about_ca_system_score_gemma":0.00013579761,"threshold_uncertainty_score":0.99999416},"labels":[],"label_agreement":null},{"id":"W4415237266","doi":"10.3389/fpsyt.2025.1683736","title":"Efficacy and safety of Shugan Jieyu Capsule in the treatment of depressive state after acute coronary syndrome: study protocol for a multicenter randomized controlled trial","year":2025,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Randomized controlled trial; Depressive symptoms; Protocol (science); Multicenter trial; Capsule; Depression (economics)","score_opus":0.008987491179423936,"score_gpt":0.3027555431013425,"score_spread":0.29376805192191857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415237266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6779269,0.00011590208,0.0002730125,0.00015417255,0.00097218365,0.32046622,0.0000299024,0.000007592367,0.00005410092],"genre_scores_gemma":[0.6856878,0.000027802318,0.0006009795,0.000118199234,0.000008868793,0.31343943,0.0000010986254,0.000010780412,0.0001050397],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9975386,0.00080658373,0.0008438476,0.00039146445,0.00018374805,0.00023575386],"domain_scores_gemma":[0.9988141,0.00054963253,0.00028522292,0.00030353802,0.000020141451,0.0000273762],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042643383,0.00022472504,0.0011755177,0.00024943246,0.00004969446,0.000018161829,0.00023563053,0.00006091648,0.0000073507617],"category_scores_gemma":[0.00017304329,0.00013444164,0.00024123142,0.00025799693,0.00024040745,0.0000671477,0.000027601696,0.000091001755,1.6864628e-7],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.97549576,0.006305078,0.013463352,0.00007274111,0.00024967463,0.000015349642,0.0030970627,0.000018873572,0.00007595303,0.000026002272,0.00041614482,0.00076398824],"study_design_scores_gemma":[0.96895176,0.001731688,0.026672525,0.00010259378,0.00014102829,0.0000015534913,0.00097032415,0.00035922657,0.00021481697,0.00069103774,0.00005261801,0.000110796645],"about_ca_topic_score_codex":0.00001687134,"about_ca_topic_score_gemma":0.000051299605,"teacher_disagreement_score":0.013209173,"about_ca_system_score_codex":0.00003526211,"about_ca_system_score_gemma":0.00011078895,"threshold_uncertainty_score":0.5482371},"labels":[],"label_agreement":null},{"id":"W4415295457","doi":"10.1038/s41398-025-03643-6","title":"White matter free water and depressive symptoms in medication-free depressed adolescents: moderation by peripheral inflammation","year":2025,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"White matter; Major depressive disorder; Peripheral; Moderation; Pathophysiology; Inflammation; Magnetic resonance imaging","score_opus":0.005589667530864622,"score_gpt":0.2299274598171115,"score_spread":0.22433779228624687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415295457","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9357305,0.0004031124,0.01820555,0.040745117,0.00048743782,0.00056446396,0.00007350857,0.0000807569,0.0037095193],"genre_scores_gemma":[0.9966178,0.000015998769,0.00036823412,0.0025215358,0.00006493059,0.00005712029,0.00008958419,0.000014417792,0.00025039903],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986746,0.00009550636,0.00033201647,0.00040333273,0.00028440915,0.0002101624],"domain_scores_gemma":[0.9995446,0.000040004998,0.00004949265,0.0002941799,0.000024675244,0.00004700069],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007230512,0.00015978522,0.00012226375,0.00015168739,0.00013934901,0.00007744756,0.0002825296,0.00011627172,0.00020233169],"category_scores_gemma":[0.000028524073,0.00014119025,0.00003912074,0.00015395925,0.00009466809,0.0004335245,0.000032628635,0.0001655895,0.000013060011],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002913003,0.00025181155,0.9079731,0.00022072638,0.000021715288,9.563893e-7,0.001312568,0.0022506898,0.06217694,0.0096737975,0.013999416,0.0018269954],"study_design_scores_gemma":[0.0067262696,0.000020361853,0.8818326,0.00020535685,0.00001969608,0.00000367757,0.000045648034,0.012423836,0.015872937,0.08195776,0.0005369971,0.00035484007],"about_ca_topic_score_codex":0.000013592097,"about_ca_topic_score_gemma":0.00016793933,"teacher_disagreement_score":0.07228396,"about_ca_system_score_codex":0.000018056611,"about_ca_system_score_gemma":0.000052677045,"threshold_uncertainty_score":0.5757571},"labels":[],"label_agreement":null},{"id":"W4415449982","doi":"10.1210/jendso/bvaf149.1971","title":"SAT-122 The Role of Targeted Plasma Proteomics for Identifying Inflammatory Signatures Associated with Risk for Perinatal Depression","year":2025,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université Laval","keywords":"Depression (economics); Pregnancy; Pregnancy-associated plasma protein A; Disease; Proteomics; Gestation; Postpartum depression; Inflammation","score_opus":0.009758964220218656,"score_gpt":0.2557962518005394,"score_spread":0.24603728758032073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415449982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99667835,0.00037100803,0.0011968692,0.0005365558,0.00030614095,0.00078094343,0.00006708145,0.000015229185,0.000047839236],"genre_scores_gemma":[0.9981199,0.000050783477,0.0012684527,0.00021508068,0.00006685862,0.000033889515,9.80845e-7,0.000016714972,0.0002273293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988831,0.00012281115,0.00033519603,0.0001419822,0.00029029752,0.00022658228],"domain_scores_gemma":[0.9980267,0.00085563253,0.0007504039,0.00017555131,0.0001631511,0.000028508462],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038309942,0.00013088498,0.00020565988,0.00003278259,0.00044276865,0.000045746045,0.00056792767,0.000053655,0.0000028717668],"category_scores_gemma":[0.001967079,0.00006742394,0.0005020085,0.00022048659,0.00015584391,0.00014553264,0.000120003766,0.0004138054,1.0414151e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095915404,0.000285114,0.0101166265,0.00018006102,0.0003446332,0.0000022375662,0.0017922468,0.0025849,0.97393215,0.0007998485,0.0066482914,0.0023547458],"study_design_scores_gemma":[0.004202819,0.00012353598,0.012062322,0.00019765402,0.00009333006,0.000012656268,0.0014254634,0.0043679033,0.96942496,0.004437022,0.0035423078,0.00010999823],"about_ca_topic_score_codex":0.0000028807526,"about_ca_topic_score_gemma":0.000007967546,"teacher_disagreement_score":0.004507153,"about_ca_system_score_codex":0.000060898015,"about_ca_system_score_gemma":0.00014614215,"threshold_uncertainty_score":0.34054634},"labels":[],"label_agreement":null},{"id":"W4415717658","doi":"10.5498/wjp.v15.i11.110690","title":"Cognitive impairment and pain in depression: The mediating role of the kynurenine pathway","year":2025,"lang":"en","type":"article","venue":"World Journal of Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Cognitive impairment; Kynurenine pathway; Depression (economics); Biomarker; Cognition; Kynurenine","score_opus":0.0067839039502277775,"score_gpt":0.24707045102700068,"score_spread":0.2402865470767729,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415717658","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98235655,0.005106409,0.00004501926,0.008366436,0.00086355174,0.00018614004,0.0000058829414,0.000004721144,0.0030652897],"genre_scores_gemma":[0.9978583,0.000052285955,0.00012894327,0.0017580172,0.00008143066,0.0000026048292,7.243418e-8,0.0000045547336,0.000113831724],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989038,0.00032415596,0.0003354143,0.000102389335,0.00021061797,0.0001236384],"domain_scores_gemma":[0.9990464,0.00050234096,0.00029400404,0.000101963284,0.000025954289,0.000029354402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006720069,0.00007955459,0.00012978923,0.00012621326,0.00010079642,0.00001737465,0.00024976334,0.000022838238,0.00002170285],"category_scores_gemma":[0.0004245191,0.00004091913,0.00007870771,0.0005084922,0.00011371089,0.000055623903,0.000070711845,0.00030654165,3.1909337e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047845658,0.0006267662,0.78577816,0.00009103626,0.000041512307,0.000008202789,0.0028563181,0.00008937956,0.049957227,0.008309779,0.004521153,0.147242],"study_design_scores_gemma":[0.0046625854,0.0002816529,0.8518127,0.0020572501,0.000043050197,0.000048753627,0.009146993,0.00041808942,0.08044407,0.04647552,0.004392773,0.00021656744],"about_ca_topic_score_codex":0.0000050134367,"about_ca_topic_score_gemma":0.00021106868,"teacher_disagreement_score":0.14702542,"about_ca_system_score_codex":0.000010152051,"about_ca_system_score_gemma":0.00012990857,"threshold_uncertainty_score":0.16686337},"labels":[],"label_agreement":null},{"id":"W4415880045","doi":"10.1016/j.bbi.2025.106173","title":"Developing interferon-β as a safe in vivo experimental-medicine model of human inflammation","year":2025,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council","keywords":"Inflammation; In vivo; Systemic inflammation; Transient (computer programming); Animal model","score_opus":0.05917878179215858,"score_gpt":0.3508322260230654,"score_spread":0.29165344423090683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415880045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941999,0.000063146086,0.00019501743,0.00047275875,0.00005263648,0.000249406,0.0000029508392,0.000023644197,0.0047405437],"genre_scores_gemma":[0.9987663,0.000017068001,0.0000753894,0.0004330093,0.0000050074423,0.00003622914,0.0000027545177,0.0000063484395,0.0006578785],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919486,0.00010677226,0.00028741884,0.00017268474,0.00010103102,0.00013721181],"domain_scores_gemma":[0.9996113,0.00009982773,0.000062150575,0.00018511829,0.00001683138,0.000024729074],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016518909,0.00011154386,0.00017112604,0.00021605004,0.0001253563,0.000013633546,0.00017742896,0.00005662745,0.00007306657],"category_scores_gemma":[0.00019803409,0.00010643109,0.000023338644,0.00024227833,0.0002235288,0.00014163154,0.0001333204,0.00013979085,0.000001330969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000330681,0.0000826209,0.0007591889,0.000023269697,8.7434745e-7,0.0000012270049,0.00207016,0.000004761562,0.9839387,0.010851052,0.00007616253,0.002158942],"study_design_scores_gemma":[0.0010919331,0.000132618,0.0149503015,0.00016007696,0.0000039150937,0.0000017973874,0.0017063945,0.00024307115,0.98000246,0.0015296526,0.00006800722,0.000109768225],"about_ca_topic_score_codex":0.00030105395,"about_ca_topic_score_gemma":0.00005708056,"teacher_disagreement_score":0.0141911125,"about_ca_system_score_codex":0.00005032043,"about_ca_system_score_gemma":0.000047839614,"threshold_uncertainty_score":0.43401343},"labels":[],"label_agreement":null},{"id":"W4416283119","doi":"10.3390/healthcare13222943","title":"Managing Symptoms in Adolescent-Onset Schizophrenia: A Narrative Review of Therapeutic Interventions","year":2025,"lang":"en","type":"article","venue":"Healthcare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Psychosocial; Psychological intervention; Aripiprazole; Neuroimaging; Cognitive behavioral therapy; Schizophrenia (object-oriented programming); Quetiapine; Neurocognitive; Psychosis; Amisulpride","score_opus":0.055306993736248124,"score_gpt":0.3740658688298522,"score_spread":0.31875887509360407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416283119","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.37340096,0.40748847,0.0012956568,0.2036081,0.0016303398,0.0049241907,0.0001460638,0.00038456058,0.007121643],"genre_scores_gemma":[0.97769326,0.010347377,0.000025595322,0.011630536,0.0000065207682,0.000046953373,0.000003613601,0.0000074598297,0.00023870761],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.99865377,0.00034039567,0.0003845871,0.0002751609,0.00013220811,0.00021388601],"domain_scores_gemma":[0.99948865,0.00008801419,0.000100243094,0.00024494843,0.00003776946,0.000040347695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016598766,0.00010584438,0.00024387855,0.00020935533,0.00007679774,0.000009520187,0.0002109795,0.000041047428,0.000046939153],"category_scores_gemma":[0.00018489551,0.000099220284,0.00013203968,0.00083875697,0.00008181911,0.000064432235,0.000058935515,0.00023027686,0.000010095967],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005869422,0.0015635401,0.032192223,0.21298033,0.000066823646,0.00007116308,0.007808599,0.000019397929,0.0043825395,0.0998256,0.010691091,0.62981176],"study_design_scores_gemma":[0.008150628,0.00079598126,0.31886455,0.55330503,0.00008803997,0.000049533952,0.010357082,0.00089041283,0.021733608,0.07378192,0.010642886,0.0013403292],"about_ca_topic_score_codex":0.000052492876,"about_ca_topic_score_gemma":0.00021883918,"teacher_disagreement_score":0.62847143,"about_ca_system_score_codex":0.000058276666,"about_ca_system_score_gemma":0.000117599004,"threshold_uncertainty_score":0.40460858},"labels":[],"label_agreement":null},{"id":"W4416407115","doi":"10.1038/s41380-025-03337-x","title":"Investigating the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences","year":2025,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; McGill University; Douglas Mental Health University Institute; Lawson Health Research Institute; Western University","funders":"Medical Research Foundation; Medical Research Council; Fonds de Recherche du Québec - Santé; McGill University","keywords":"Glutamate receptor; Psychosis; Schizophrenia (object-oriented programming); Anterior cingulate cortex; Neurotransmitter; Pathophysiology; Antipsychotic; gamma-Aminobutyric acid","score_opus":0.012452371808854371,"score_gpt":0.261145219662961,"score_spread":0.24869284785410664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416407115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98802346,0.0033807382,0.00009850797,0.007365384,0.00022957298,0.00021129065,0.0000035379326,0.000020578587,0.0006669068],"genre_scores_gemma":[0.9951769,0.00020212417,0.00011503016,0.0044463743,0.000007659281,0.000022871864,3.7499564e-7,0.000006169506,0.000022471606],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990564,0.0001437479,0.00017053286,0.0003588532,0.00009341418,0.00017703122],"domain_scores_gemma":[0.99970645,0.00010052389,0.000036255726,0.0001076995,0.0000055881974,0.00004346522],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001310421,0.000111939815,0.000110274086,0.000084989726,0.000112147165,0.000070392576,0.00008062538,0.00004602144,0.0000024979754],"category_scores_gemma":[0.00021488343,0.000088325774,0.000013859487,0.00040660676,0.00033366203,0.00007679648,0.00004475525,0.0002071275,0.0000010246299],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006423113,0.000103102946,0.41979402,0.00018547817,0.000009173752,0.000017342927,0.000494415,0.000021175618,0.31853738,0.25763413,0.00024852902,0.0028910397],"study_design_scores_gemma":[0.0017546362,0.00009862199,0.90761375,0.00033766715,0.00001696446,0.000032880092,0.0006288885,0.0028305356,0.017555382,0.068108685,0.00071776815,0.0003042102],"about_ca_topic_score_codex":0.000036965026,"about_ca_topic_score_gemma":0.00024370028,"teacher_disagreement_score":0.48781973,"about_ca_system_score_codex":0.000010934315,"about_ca_system_score_gemma":0.000037073896,"threshold_uncertainty_score":0.36018205},"labels":[],"label_agreement":null},{"id":"W4416456059","doi":"10.3892/br.2025.2090","title":"Janus kinase/signal transducer and activator of transcription pathway in schizophrenia (Review)","year":2025,"lang":"en","type":"review","venue":"Biomedical Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Transcription factor; Signal transduction; Schizophrenia (object-oriented programming); STAT protein; Activator (genetics); Janus kinase; Hippo signaling pathway; Synaptic plasticity","score_opus":0.0344550920877007,"score_gpt":0.30779533707268303,"score_spread":0.27334024498498233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416456059","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00013812046,0.99752176,0.000061724124,0.00012448254,0.00042856825,0.0010457555,0.000075095704,0.000041764593,0.0005627417],"genre_scores_gemma":[0.0013431839,0.9980179,0.000045316174,0.00020345935,0.000054506894,0.00010987376,0.000041598414,0.000025728694,0.00015844175],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965217,0.0003132074,0.0013688168,0.0008542127,0.0006166329,0.0003254087],"domain_scores_gemma":[0.9985885,0.00034620185,0.00046543853,0.000374091,0.000021201566,0.00020455188],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004872379,0.00039552312,0.001628836,0.00041208448,0.00003757074,0.000012911184,0.00021414652,0.00040199587,0.00029305456],"category_scores_gemma":[0.0009848613,0.00030130148,0.00041745687,0.0010022499,0.00037426528,0.00008168268,0.000043879245,0.00046094853,0.0000046687687],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012037945,0.00018375325,3.7888492e-7,0.044863116,0.000009913624,0.0005814315,0.000014720797,3.8877235e-9,0.0020715343,0.00007415606,0.00043792435,0.95175105],"study_design_scores_gemma":[0.00029813228,0.000064035965,0.000020781545,0.05825329,0.00008773611,0.00023492156,0.0000028261302,4.7671355e-7,0.0012367218,0.00018718008,0.9393276,0.00028630422],"about_ca_topic_score_codex":0.000019523683,"about_ca_topic_score_gemma":0.000003681587,"teacher_disagreement_score":0.9514647,"about_ca_system_score_codex":0.000050010975,"about_ca_system_score_gemma":0.00097587105,"threshold_uncertainty_score":0.9999439},"labels":[],"label_agreement":null},{"id":"W4416504130","doi":"10.1186/s12991-025-00609-2","title":"Pro-inflammatory cytokines level in depressed patients with suicidal behaviour: a systematic review and meta-analysis","year":2025,"lang":"en","type":"review","venue":"Annals of General Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Geriatric psychiatry; Suicidal ideation; Forensic psychiatry; Psychopharmacology; Depression (economics); Poison control; Suicide prevention; Human factors and ergonomics","score_opus":0.13080605292254988,"score_gpt":0.3670722878590368,"score_spread":0.2362662349364869,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416504130","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027782837,0.99517596,0.0000062314007,0.00027789702,0.00007477258,0.0034899076,0.0005577319,0.000028914179,0.000110733534],"genre_scores_gemma":[0.00017333779,0.99612546,0.00018574712,0.0020034518,0.000017104796,0.00063575426,0.00006347089,0.000044475655,0.000751212],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9958137,0.0007871496,0.0015877091,0.0009043222,0.0005175882,0.00038952995],"domain_scores_gemma":[0.997484,0.00018866191,0.001195109,0.0008964305,0.00012741023,0.00010836246],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040764073,0.0006787938,0.0064714425,0.0007743387,0.000067102155,0.000049066635,0.0006508683,0.00021416329,0.00005578167],"category_scores_gemma":[0.00024851484,0.00042571314,0.0018238146,0.0018067299,0.00011901594,0.00014153717,0.00012849091,0.00029866572,0.000004805281],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010586007,0.00027792103,0.0006293188,0.985098,0.012269568,0.0000043987334,0.000011084437,0.0000038045036,3.1576675e-7,0.0002106295,0.0010614228,0.00042291975],"study_design_scores_gemma":[0.0007772588,0.00020309925,0.0014450599,0.08335352,0.9100503,0.0000090303665,0.000009321922,0.0000036962315,0.000024423965,0.0001488261,0.0023996267,0.0015758465],"about_ca_topic_score_codex":0.000043035,"about_ca_topic_score_gemma":0.00024819735,"teacher_disagreement_score":0.9017445,"about_ca_system_score_codex":0.000010522837,"about_ca_system_score_gemma":0.00029346664,"threshold_uncertainty_score":0.99981946},"labels":[],"label_agreement":null},{"id":"W4416540176","doi":"","title":"Adli psikiyatri servisinde takip edilen şizofreni tanılı hastaların saldırganlık, depresyon ve hastalık şiddeti ile bazı kan parametreleri arasındaki ilişkinin incelenmesi","year":2024,"lang":"en","type":"article","venue":"DergiPark (Istanbul University)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Aggression; Depression (economics); Diagnosis of schizophrenia; Positive and Negative Syndrome Scale; Forensic psychiatry; Depressive symptoms","score_opus":0.018591355815560106,"score_gpt":0.22189229022204057,"score_spread":0.20330093440648048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416540176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8972195,0.0014961506,0.0033671833,0.001710831,0.0019918797,0.0011332058,0.00053871685,0.002043973,0.0904986],"genre_scores_gemma":[0.98280525,0.0004690408,0.00066541706,0.0006573326,0.00026086177,0.000007393724,0.000071720446,0.00015014695,0.014912857],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.994577,0.00043875587,0.0005655648,0.0020334148,0.001011742,0.0013735323],"domain_scores_gemma":[0.997053,0.0008665287,0.0002351896,0.0011553894,0.00011915955,0.0005707046],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000289192,0.00081857445,0.00067334156,0.0011976061,0.0006897399,0.00061098457,0.0016054878,0.00043986604,0.0014533376],"category_scores_gemma":[0.00040099985,0.00091546634,0.00046535148,0.0038065852,0.00069398776,0.001216051,0.00063548324,0.000990199,0.0009284612],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044551976,0.0033137344,0.0039909743,0.0020937992,0.0009613734,0.028074475,0.016123893,0.0031792966,0.3256717,0.21318561,0.33327675,0.06567319],"study_design_scores_gemma":[0.0021864213,0.0003714776,0.0015749194,0.00026882457,0.0001303259,0.00011285282,0.00392295,0.001989507,0.048700865,0.0015737013,0.9376562,0.0015119181],"about_ca_topic_score_codex":0.00018288965,"about_ca_topic_score_gemma":0.000369741,"teacher_disagreement_score":0.6043795,"about_ca_system_score_codex":0.00048869103,"about_ca_system_score_gemma":0.00052991917,"threshold_uncertainty_score":0.99984944},"labels":[],"label_agreement":null},{"id":"W4416549129","doi":"10.1016/j.pnpbp.2025.111567","title":"Mechanistic insights into the antidepressant potential of plant-derived flavonoids: A preclinical review","year":2025,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; China Scholarship Council","keywords":"Antidepressant; Flavonols; Flavones; Isoflavones; Neurotrophic factors; Neurotransmitter; Flavonoid; Human studies; Depression (economics)","score_opus":0.026969815747571294,"score_gpt":0.34003145822925185,"score_spread":0.31306164248168056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416549129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9236962,0.061604593,0.00006615257,0.01036883,0.0026405724,0.0011914256,0.000014671303,0.00008244016,0.00033506908],"genre_scores_gemma":[0.9346717,0.046162404,0.00014874898,0.018747818,0.00008236324,0.0001616584,0.0000045287406,0.000009421171,0.000011335649],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9969184,0.0009593308,0.0007326842,0.00085690187,0.00015032553,0.00038238266],"domain_scores_gemma":[0.9984926,0.0008588879,0.00023438748,0.00030148437,0.000028276354,0.00008436276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034563724,0.00028675524,0.00051862694,0.00013525413,0.00021201381,0.000020931513,0.0007157135,0.00025441195,0.00008043275],"category_scores_gemma":[0.00043986642,0.00017036062,0.0001464762,0.0005802487,0.0012759884,0.000062106265,0.0002789992,0.0006875167,0.0000070103606],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015392215,0.009471783,0.44753945,0.0056340974,0.00032247434,0.00045292533,0.00064849964,0.00001898137,0.26701787,0.08517075,0.028638955,0.13969201],"study_design_scores_gemma":[0.013350458,0.0022019546,0.84450006,0.0019972187,0.00026768798,0.000114091854,0.00018065212,0.0011831236,0.008962665,0.10857529,0.017514773,0.0011519955],"about_ca_topic_score_codex":0.0000021958765,"about_ca_topic_score_gemma":0.0000063021553,"teacher_disagreement_score":0.39696065,"about_ca_system_score_codex":0.0000066366556,"about_ca_system_score_gemma":0.00006980908,"threshold_uncertainty_score":0.69471043},"labels":[],"label_agreement":null},{"id":"W4416762761","doi":"10.1016/j.bbih.2025.101144","title":"Immune and metabolic disturbance as a function of genetic risk and phase of illness in major depression","year":2025,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medicinska Forskningsrådet; Wellcome Trust; Medical Research Council; Office of Research and Development; Health Services Research and Development; Region Östergötland; Alberta Law Foundation","keywords":"Depression (economics); Major depressive disorder; Confounding; Immune system; Risk factor; Antidepressant; Epidemiology; Immune Dysfunction; Inflammation","score_opus":0.020398195567906546,"score_gpt":0.3224129039467161,"score_spread":0.30201470837880956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416762761","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896189,0.009028574,0.00022124797,0.00021831202,0.00012190711,0.00065699854,0.000055234,0.000023673581,0.00005515933],"genre_scores_gemma":[0.99760187,0.0018023052,0.00010725002,0.00031983329,0.0000042500787,0.000051086852,0.000005881886,0.000012509209,0.00009503446],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99812055,0.0006165807,0.0005355258,0.0003117219,0.00016333097,0.0002523159],"domain_scores_gemma":[0.9988789,0.00031366892,0.00030813334,0.00039861593,0.000027524571,0.00007314267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045151968,0.00015983949,0.00040280452,0.0002654102,0.0002277606,0.000015833906,0.00018088162,0.00007745418,0.00001668071],"category_scores_gemma":[0.00047682153,0.00015333218,0.000046563047,0.00058684463,0.00030422036,0.00011619428,0.00014236933,0.00028518296,6.5724504e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005548607,0.0013950539,0.06587081,0.0003215991,0.0000062312256,0.000003910999,0.002197974,0.0000032545006,0.4298792,0.00072173413,0.000036979745,0.4990084],"study_design_scores_gemma":[0.0033984035,0.00025027595,0.93794703,0.00013771025,0.000024661214,0.0000060986754,0.0006376071,0.000030139227,0.056696307,0.00037350113,0.000376899,0.000121359655],"about_ca_topic_score_codex":0.0037947383,"about_ca_topic_score_gemma":0.00022110228,"teacher_disagreement_score":0.8720762,"about_ca_system_score_codex":0.000022348544,"about_ca_system_score_gemma":0.00014193948,"threshold_uncertainty_score":0.6252704},"labels":[],"label_agreement":null},{"id":"W4416827190","doi":"10.1038/s41398-025-03776-8","title":"Integrative neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder","year":2025,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Israel Science Foundation; Ministério da Ciência, Tecnologia e Inovação; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Neuroimmunology; Transcriptome; Major depressive disorder; Biomarker; Immune system; Schizophrenia (object-oriented programming); PAX6; DISC1","score_opus":0.015627057572003354,"score_gpt":0.3074876075805923,"score_spread":0.29186055000858896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416827190","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9285619,0.0032138317,0.018263439,0.018139051,0.0018041866,0.00059728784,0.00015655126,0.00016965627,0.029094085],"genre_scores_gemma":[0.99615604,0.000030922303,0.0015219222,0.0016809849,0.000058425285,0.00003586625,0.00001094034,0.000019225143,0.00048570323],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99822646,0.00023794486,0.00045683127,0.0005030419,0.00028511885,0.0002906051],"domain_scores_gemma":[0.9986192,0.000885922,0.00009841649,0.00026635293,0.000074839096,0.000055241802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007276856,0.00022024087,0.00027884444,0.0002016249,0.00021264206,0.000032056243,0.00035236432,0.00014533635,0.0003255384],"category_scores_gemma":[0.0006267655,0.00019638643,0.00016537891,0.00043584348,0.000565351,0.00023068373,0.000034687986,0.00032976238,0.000025048557],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00087382534,0.0007955461,0.031062407,0.00022673553,0.0000647076,0.000006161527,0.00087094697,0.00015237283,0.26068637,0.7000381,0.0024770424,0.002745811],"study_design_scores_gemma":[0.006044265,0.00034230045,0.26212773,0.00066506944,0.00011171461,0.000033122953,0.000711801,0.0010894105,0.06091833,0.6646225,0.0027107913,0.0006229782],"about_ca_topic_score_codex":0.000018801478,"about_ca_topic_score_gemma":0.000018563638,"teacher_disagreement_score":0.23106532,"about_ca_system_score_codex":0.000010858947,"about_ca_system_score_gemma":0.0003023729,"threshold_uncertainty_score":0.8008406},"labels":[],"label_agreement":null},{"id":"W4416931838","doi":"10.1093/brain/awaf455","title":"Immune alterations in schizophrenia and the effects of a therapeutic antibody: a neuroimaging study","year":2025,"lang":"en","type":"article","venue":"Brain","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"Medical Research Council; NIHR Great Ormond Street Hospital Biomedical Research Centre; Centro Singular de Investigación de Galicia; University College London; King's College London; Department of Health and Social Care; National Institute for Health and Care Research; Wellcome Trust; South London and Maudsley NHS Foundation Trust; NIHR BioResource; Maudsley Charity; Medical Research Council Canada; NHS Blood and Transplant","keywords":"Natalizumab; Translocator protein; Neuroinflammation; Neuroimaging; Schizophrenia (object-oriented programming); Psychosis; Grey matter; Temporal lobe; Placebo","score_opus":0.009932129112839118,"score_gpt":0.28769968916262423,"score_spread":0.2777675600497851,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416931838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99365175,0.00044516416,0.00017690314,0.0022981856,0.000078729725,0.0006988539,4.9730414e-7,0.000025727199,0.0026241809],"genre_scores_gemma":[0.99806786,0.0000141096525,0.0000126794575,0.0012377118,0.00000416604,0.000025629042,1.3157513e-7,0.000007779606,0.00062994304],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991958,0.00033046145,0.00013040143,0.00017338457,0.000069255875,0.00010069795],"domain_scores_gemma":[0.99867815,0.0010965382,0.000032889995,0.00017855946,0.0000041988646,0.000009684943],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015641439,0.00006930977,0.00012383581,0.0001245127,0.00006703328,0.00003478228,0.00013519375,0.000011472986,0.000005193163],"category_scores_gemma":[0.0007590794,0.000047985624,0.000024834206,0.0004141595,0.00016070523,0.000045374938,0.00006240119,0.00008443625,0.0000022169456],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002180188,0.00032091019,0.0029212965,0.000054428645,0.000010004741,0.0000133698695,0.0023521674,0.0000050141457,0.93537027,0.04237527,0.0000606863,0.01629859],"study_design_scores_gemma":[0.02296875,0.00023683312,0.86696225,0.00021173604,0.000025661799,0.000007750839,0.0009632546,0.0034984737,0.09092094,0.013490344,0.00047860414,0.00023538106],"about_ca_topic_score_codex":0.000048906277,"about_ca_topic_score_gemma":0.000033922588,"teacher_disagreement_score":0.864041,"about_ca_system_score_codex":0.0000030328893,"about_ca_system_score_gemma":0.0000199732,"threshold_uncertainty_score":0.1956797},"labels":[],"label_agreement":null},{"id":"W4416946689","doi":"10.1038/s41398-025-03772-y","title":"Epigenetic and blood markers associated with response to electroconvulsive therapy in patients with depressive disorders","year":2025,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Norges Forskningsråd; Universitetet i Bergen; Helse Vest","keywords":"Cohort; Epigenetics; DNA methylation; CpG site; Schizophrenia (object-oriented programming); Methylation; Norwegian; Cohort study; Major depressive disorder","score_opus":0.00441478954182236,"score_gpt":0.22138598789936278,"score_spread":0.21697119835754042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416946689","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943505,0.00016505494,0.00030446742,0.0036177426,0.000054842316,0.00077892217,0.000025734025,0.000034876724,0.0006678554],"genre_scores_gemma":[0.99791443,0.000019322217,0.00030325595,0.0015962989,0.0000049592086,0.00005204299,0.000008813849,0.000017645774,0.000083214654],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99873334,0.00018628487,0.00016019908,0.0004168772,0.00024865865,0.0002546402],"domain_scores_gemma":[0.9994076,0.00032944165,0.00004956877,0.00012377591,0.000030064215,0.000059548955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008347844,0.00017117565,0.00013801735,0.00022339448,0.000111261856,0.000027786002,0.00012839478,0.00005728739,0.000024029796],"category_scores_gemma":[0.0000650305,0.00013869087,0.00002544752,0.00069904595,0.00009899328,0.00008959419,0.0000065169465,0.00013867133,0.0000017942019],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013417311,0.0006451626,0.9798013,0.000009268487,0.000059683807,0.0000011834151,0.00032216456,0.00034534917,0.0023423058,0.0007512197,0.000071150105,0.0022338808],"study_design_scores_gemma":[0.008527922,0.00074078346,0.9875256,0.00007297839,0.000011753207,2.963065e-7,0.00003509779,0.000022675005,0.00087894767,0.0019309204,0.000066905806,0.00018612918],"about_ca_topic_score_codex":0.0000079862075,"about_ca_topic_score_gemma":0.0004511797,"teacher_disagreement_score":0.0077242698,"about_ca_system_score_codex":0.000012092058,"about_ca_system_score_gemma":0.0001790582,"threshold_uncertainty_score":0.565565},"labels":[],"label_agreement":null},{"id":"W4417068346","doi":"10.7150/ijbs.123740","title":"Disrupted astrocyte-neuron glutamine-glutamate cycling in the medial prefrontal cortex contributes to depression-like behaviors","year":2025,"lang":"en","type":"article","venue":"International Journal of Biological Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"Ministry of Science and ICT, South Korea; Gyeongsang National University; National Research Foundation","keywords":"Prefrontal cortex; Conditional gene knockout; Glutamatergic; Glutamate receptor; Homeostasis; Glutamine; Glutamine synthetase; Phenotype","score_opus":0.03220452510976767,"score_gpt":0.3398937118497667,"score_spread":0.307689186739999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417068346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99300015,0.00010833634,0.0005898274,0.0038856806,0.001575176,0.00014432837,0.000013408175,0.00001239881,0.0006706858],"genre_scores_gemma":[0.9968308,0.000059757793,0.0001576723,0.0028306518,0.00008447157,0.0000068517757,9.787101e-7,0.0000019150823,0.000026891405],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981925,0.00022793155,0.00046266947,0.000277077,0.00059031555,0.00024951415],"domain_scores_gemma":[0.99866885,0.00092379126,0.00020006967,0.00006831911,0.00007880694,0.000060163828],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006895389,0.00011828523,0.00017478556,0.00025939028,0.00014253182,0.0001744129,0.0016008379,0.000061597726,0.000040374336],"category_scores_gemma":[0.0019164163,0.00006121826,0.00009917984,0.00049005216,0.00041751622,0.00018609515,0.00018590997,0.00023529964,0.000007112412],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039003667,0.0003348684,0.10928008,0.0000014179138,0.000008552516,0.00015701842,0.00026387552,0.00029580455,0.8735859,0.001634926,0.00033136448,0.013716153],"study_design_scores_gemma":[0.0010387264,0.00037092232,0.94023967,0.000119118165,0.000006452527,0.00008644256,0.0006140589,0.00030273682,0.052476637,0.002325192,0.002289086,0.00013096498],"about_ca_topic_score_codex":0.000017995379,"about_ca_topic_score_gemma":0.00003704589,"teacher_disagreement_score":0.83095956,"about_ca_system_score_codex":0.00005359765,"about_ca_system_score_gemma":0.000073044874,"threshold_uncertainty_score":0.29747817},"labels":[],"label_agreement":null},{"id":"W4417191338","doi":"10.1038/s41598-025-31573-2","title":"Chronic gut inflammation differentially modulates mitochondrial and antioxidant transcriptional programs in limbic brain structures","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Manitoba; University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Children’s Hospital of Wisconsin Research Institute; Azrieli Foundation; Genome Canada","keywords":"Inflammation; Nucleus accumbens; Mitochondrion; Gene expression; Chronic pain; Cytochrome c oxidase; Limbic system; Central nervous system","score_opus":0.017227621577319264,"score_gpt":0.24696175401899753,"score_spread":0.22973413244167826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417191338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99278486,0.0002102141,0.00029076225,0.0008880811,0.0047958456,0.0006275913,0.0000020456641,0.00008536845,0.00031525653],"genre_scores_gemma":[0.9979893,0.000007887639,0.00013959628,0.000044404336,0.00009578825,0.00003535047,0.000022756183,0.00000922326,0.0016556855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978165,0.00009550721,0.000479159,0.00087158766,0.0004087629,0.0003284692],"domain_scores_gemma":[0.9993542,0.000054994565,0.00013759789,0.00035437534,0.000037623533,0.00006119689],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026171,0.00016643327,0.00017478103,0.00036745035,0.00026005326,0.0005351388,0.0001478863,0.0000872748,0.000056657405],"category_scores_gemma":[0.00031143246,0.00014856017,0.00007277804,0.0006823772,0.00043158824,0.000317817,0.000056341225,0.00014249387,0.0000030058525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016753855,0.00004391095,0.0012065069,0.00004685752,0.0000036265594,0.0000539528,0.00026056904,0.00009979365,0.9739535,0.004006624,0.00032687196,0.019981032],"study_design_scores_gemma":[0.0016280779,0.000103021834,0.20657606,0.00024222133,0.000014910485,0.0001231721,0.00011070613,0.0024367387,0.5861799,0.18646894,0.015618794,0.0004974521],"about_ca_topic_score_codex":0.00002024408,"about_ca_topic_score_gemma":0.00031266978,"teacher_disagreement_score":0.3877736,"about_ca_system_score_codex":0.00005760715,"about_ca_system_score_gemma":0.00020150864,"threshold_uncertainty_score":0.60581076},"labels":[],"label_agreement":null},{"id":"W4417255595","doi":"10.1021/acsomega.5c09713","title":"Higher Plasma Kynurenine to Tryptophan Correlates with an Increased Incidence of Mild Cognitive Impairment in Treated Metabolic Syndrome Patients","year":2025,"lang":"en","type":"article","venue":"ACS Omega","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Research Council of Thailand; Center of Excellence for Innovation in Chemistry; Faculty of Medicine, Chiang Mai University; Mahidol University; Faculty of Medicine Siriraj Hospital, Mahidol University; Ministry of Higher Education and Scientific Research; Chiang Mai University","keywords":"Kynurenine; Metabolic syndrome; Metabolite; Cognition; Kynurenine pathway; Incidence (geometry); Cognitive impairment","score_opus":0.0115386286378753,"score_gpt":0.25030487088620257,"score_spread":0.23876624224832727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417255595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981059,0.000053283773,0.000005751826,0.00008986544,0.00010495532,0.00078224787,0.00006932762,0.00006911227,0.00071957766],"genre_scores_gemma":[0.99853814,0.000014452129,0.00006772606,0.0008314245,0.0000056883705,0.00010040201,0.000024286353,0.000022210057,0.00039567912],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99822646,0.00017258128,0.00034766732,0.0005481293,0.00033042533,0.00037473883],"domain_scores_gemma":[0.9990815,0.00029420562,0.00011744068,0.0002741199,0.000087175635,0.0001455643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000092611415,0.0002599233,0.00040342766,0.00048391699,0.000070213944,0.000031256695,0.0003367032,0.000091615424,0.00003224503],"category_scores_gemma":[0.0002462437,0.000213657,0.000042991735,0.0017461558,0.00014763429,0.00027771693,0.000099342484,0.00016382517,0.000026999825],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0082408,0.006599854,0.8784281,0.0001610553,0.00016331172,0.00032246992,0.002615736,0.00030111053,0.094058126,0.0029761298,0.00055273046,0.005580603],"study_design_scores_gemma":[0.0048369616,0.0011408906,0.81054324,0.00023523078,0.000029300807,0.000004509246,0.00010748813,0.00007024253,0.18261604,0.000120678116,0.00006128121,0.00023414058],"about_ca_topic_score_codex":0.0003621131,"about_ca_topic_score_gemma":0.00017387337,"teacher_disagreement_score":0.08855792,"about_ca_system_score_codex":0.000045535977,"about_ca_system_score_gemma":0.0000786124,"threshold_uncertainty_score":0.871268},"labels":[],"label_agreement":null},{"id":"W4417297570","doi":"10.1016/j.ebiom.2025.106062","title":"Sex-specific interaction effects of Syntaxin 1A coexpression network and childhood trauma on adult depressive symptoms","year":2025,"lang":"en","type":"article","venue":"EBioMedicine","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"BC Children's Hospital; Douglas Mental Health University Institute","funders":"Fonds de recherche du Québec; Fonds de Recherche du Québec - Santé; University of Bristol; Hope for Depression Research Foundation; Harvard University; Wellcome Trust; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; JPB Foundation; Medical Research Council; Wellcome","keywords":"Depression (economics); Depressive symptoms; Childhood abuse; Poison control; Suicide prevention; Young adult; Syntaxin; Human factors and ergonomics","score_opus":0.0064254263805586615,"score_gpt":0.2479449662902043,"score_spread":0.24151953990964564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417297570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99335456,0.000730094,0.00040056848,0.0006050053,0.0011150464,0.00042734717,0.0000049455075,0.00007447937,0.0032879263],"genre_scores_gemma":[0.9979383,0.00025269238,0.000026180654,0.0012401857,0.00016914718,0.000020863245,0.0000055808796,0.000012638973,0.00033446302],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988053,0.000116371775,0.00023466513,0.00040293246,0.00021925585,0.00022147672],"domain_scores_gemma":[0.99877137,0.00077549816,0.00011608245,0.00024480457,0.000022418137,0.00006981817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000064605556,0.00016814626,0.00026210572,0.00018469595,0.00010988111,0.000015410347,0.00014829628,0.00008089617,0.00003012109],"category_scores_gemma":[0.00026851665,0.00012892597,0.00004186188,0.00041840924,0.00019677285,0.00007683998,0.00005908558,0.00019418813,0.000007762486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045513615,0.000544397,0.0012077295,0.00027830803,0.00003723587,0.000043403354,0.0014895768,0.00004554932,0.6795334,0.0024605582,0.017294953,0.29660976],"study_design_scores_gemma":[0.003953283,0.0008779778,0.05492824,0.002590522,0.000022039565,0.000015087607,0.00019729335,0.0002341012,0.9311182,0.000923216,0.0049489103,0.00019116684],"about_ca_topic_score_codex":0.000008611121,"about_ca_topic_score_gemma":0.0000017666089,"teacher_disagreement_score":0.2964186,"about_ca_system_score_codex":0.000022139497,"about_ca_system_score_gemma":0.000011330383,"threshold_uncertainty_score":0.52574486},"labels":[],"label_agreement":null},{"id":"W4417335139","doi":"10.1016/j.jad.2025.120877","title":"Inflammatory response to repeated subcutaneous esketamine in treatment-resistant depression: The role of baseline C-reactive protein","year":2025,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Inflammatory response; Immune system; Inflammation; Baseline (sea); Pathophysiology; C-reactive protein; Major depressive disorder; Clinical trial","score_opus":0.005057117868870494,"score_gpt":0.24672132637506608,"score_spread":0.24166420850619558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417335139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959625,0.0005544143,0.0001350704,0.0010758076,0.000094132796,0.0009555761,0.000012872116,0.000015950434,0.0011936646],"genre_scores_gemma":[0.9994319,0.000036598583,0.000045653625,0.0001617988,0.000016189675,0.000043248943,4.5393975e-7,0.000017627377,0.00024654297],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973758,0.0012086377,0.0005304959,0.00029003728,0.00032810666,0.00026691885],"domain_scores_gemma":[0.99726915,0.0018272069,0.00039308297,0.0003005388,0.0001296541,0.00008033815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073576113,0.00022668028,0.00037342188,0.0005464672,0.000104357154,0.000024386987,0.00034550694,0.00007741386,0.000021193619],"category_scores_gemma":[0.004252178,0.0001471431,0.00018640253,0.0010292712,0.00016572475,0.00014864575,0.000061884675,0.00026256056,0.0000032737155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016869424,0.0005677096,0.0039157537,0.0000140359625,0.000045619832,0.000100112666,0.0013713707,0.00051627733,0.9398475,0.00013208298,0.000045164474,0.036574896],"study_design_scores_gemma":[0.0033799373,0.001997958,0.053088345,0.0002983572,0.000027990722,0.000032946115,0.0039888583,0.00018622608,0.93175936,0.0017790316,0.003260187,0.00020080716],"about_ca_topic_score_codex":0.00012464962,"about_ca_topic_score_gemma":0.00054576667,"teacher_disagreement_score":0.04917259,"about_ca_system_score_codex":0.00022227596,"about_ca_system_score_gemma":0.00029317616,"threshold_uncertainty_score":0.60003215},"labels":[],"label_agreement":null},{"id":"W4417342762","doi":"10.1097/fpc.0000000000000585","title":"Pharmacogenetic testing versus standard prescribing of psychotropics for the treatment of severe mood disorders: A randomized controlled trial protocol","year":2025,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Randomized controlled trial; Pharmacogenetics; Protocol (science); Randomization; Mood; Mood stabilizer","score_opus":0.051505005309462754,"score_gpt":0.35439083754332573,"score_spread":0.302885832233863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417342762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.64239275,0.0021443276,0.0098530855,0.00064499193,0.0015250086,0.34094238,0.00027968458,0.000051176437,0.0021665837],"genre_scores_gemma":[0.9035072,0.0034753904,0.002620208,0.00014080727,0.00017375292,0.089891076,0.0000024471549,0.00004340353,0.00014575453],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99825907,0.0002076432,0.00073204114,0.00035041096,0.00017991394,0.00027090154],"domain_scores_gemma":[0.99572337,0.003524284,0.00038239165,0.00021686112,0.000096583804,0.00005654235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029754022,0.00025278877,0.0008331489,0.00009484742,0.00018323176,0.000041076903,0.00024750302,0.000052377272,0.000011664914],"category_scores_gemma":[0.00045850882,0.00017185448,0.00035559584,0.00020942635,0.00029981023,0.000024596184,0.00004310523,0.00006161136,1.9139526e-7],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.85646254,0.00043888122,0.000027860608,0.000119795055,0.0003133274,1.5809626e-7,0.0002979019,0.0016914621,0.09642543,0.0002441847,0.000026715794,0.04395175],"study_design_scores_gemma":[0.80707866,0.001298841,0.0000051900297,0.000017877135,0.00047080693,4.7015973e-7,0.00005361465,0.021154638,0.16268355,0.0008869223,0.0062119174,0.0001375385],"about_ca_topic_score_codex":0.000006222036,"about_ca_topic_score_gemma":0.000008541988,"teacher_disagreement_score":0.2611144,"about_ca_system_score_codex":0.00003287183,"about_ca_system_score_gemma":0.00018207563,"threshold_uncertainty_score":0.70080227},"labels":[],"label_agreement":null},{"id":"W4417526946","doi":"10.1016/j.bbi.2025.106237","title":"From gut to glee: Is butyrate a promising antidepressant? A systematic review and mechanistic insights","year":2025,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universiteit van Amsterdam; Centre for Addiction and Mental Health","keywords":"Butyrate; Clinical trial; Depression (economics); Gut–brain axis; Systematic review; Mood; Gut flora; Tumor necrosis factor alpha","score_opus":0.02327214326896782,"score_gpt":0.29642088204900496,"score_spread":0.27314873878003715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417526946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9840342,0.011790141,0.00022331871,0.0011037015,0.000110033434,0.002100963,0.000077361576,0.00008936096,0.00047094686],"genre_scores_gemma":[0.98853934,0.0012593931,0.00008074789,0.00891805,0.0000075223697,0.00017689468,0.000004718758,0.000015037683,0.0009982686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847984,0.00035815107,0.00035807362,0.00042943165,0.00014969209,0.0002247928],"domain_scores_gemma":[0.99888384,0.0003732463,0.000090750436,0.00050798606,0.000035894354,0.000108281274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020133285,0.00022000876,0.0005393096,0.00011718215,0.000351667,0.00016495096,0.00027207556,0.00006970773,0.00004536027],"category_scores_gemma":[0.0011724604,0.00018425933,0.000052440704,0.00036569263,0.000097256925,0.00015177074,0.00025767917,0.00019293634,0.00001213748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003222611,0.00027363328,0.00026644513,0.030598067,0.000023881052,0.000036339217,0.0018882637,5.5894443e-8,0.96202826,0.0014095065,0.0014433496,0.001999956],"study_design_scores_gemma":[0.0067201834,0.0008497076,0.103306,0.19669999,0.004385355,0.00021313627,0.0035079892,0.0003399036,0.65968394,0.017908348,0.0026800504,0.0037054175],"about_ca_topic_score_codex":0.00024718393,"about_ca_topic_score_gemma":0.000015731997,"teacher_disagreement_score":0.30234435,"about_ca_system_score_codex":0.000018393932,"about_ca_system_score_gemma":0.00004422093,"threshold_uncertainty_score":0.7513878},"labels":[],"label_agreement":null},{"id":"W55450296","doi":"10.1080/10177833.2010.11790644","title":"Modulation of Central Nitric Oxide as a Therapeutic Strategy for Schizophrenia","year":2010,"lang":"en","type":"article","venue":"Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta; Alberta Health Services","funders":"","keywords":"Schizophrenia (object-oriented programming); Nitric oxide; Antipsychotic; Medicine; Pharmacology; Antipsychotic drug; Drug; Neuroscience; Psychology; Psychiatry; Internal medicine","score_opus":0.06589882118619105,"score_gpt":0.4100028882181596,"score_spread":0.34410406703196855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W55450296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868292,0.00012466373,0.000480472,0.0031921465,0.0033668482,0.001437329,0.0000901039,0.00013956193,0.004339639],"genre_scores_gemma":[0.99036485,0.00031008307,0.0024464957,0.0054391413,0.0006449129,0.000111920985,0.000013105562,0.00007999767,0.00058949686],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99403507,0.000764492,0.0026571576,0.0011479915,0.00048761262,0.00090768887],"domain_scores_gemma":[0.9915274,0.0057037524,0.0014217185,0.0006479598,0.00028801916,0.00041114472],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014664237,0.0004668084,0.0012028165,0.00030225093,0.00015121527,0.0000239552,0.00110315,0.0007205765,0.0022899548],"category_scores_gemma":[0.0032688456,0.00043451643,0.00083853095,0.00049710565,0.0013015912,0.00008039152,0.000118336495,0.0013186034,0.00018898763],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01317054,0.0025523072,0.0023155268,0.00015360481,0.0001542162,0.000014734279,0.00006833445,0.00036524268,0.8951741,0.0144032575,0.0131445825,0.058483567],"study_design_scores_gemma":[0.07934206,0.005583344,0.22283106,0.00009543795,0.0005791389,0.00013941903,0.00029564305,0.009730603,0.26207492,0.06072749,0.35622737,0.0023735068],"about_ca_topic_score_codex":0.000043846743,"about_ca_topic_score_gemma":0.000007796325,"teacher_disagreement_score":0.63309914,"about_ca_system_score_codex":0.000014554371,"about_ca_system_score_gemma":0.00031009415,"threshold_uncertainty_score":0.99981064},"labels":[],"label_agreement":null},{"id":"W585122078","doi":"10.1503/jpn.140126","title":"Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia — significance for activation of the kynurenine pathway","year":2015,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":225,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Kynurenine; Cerebrospinal fluid; Schizophrenia (object-oriented programming); Kynurenine pathway; Cytokine; Kynurenic acid; Interleukin; Internal medicine; Medicine; Endocrinology; Chemistry; Tryptophan; Psychiatry; Receptor; Biochemistry","score_opus":0.02792172377159215,"score_gpt":0.25340618986828684,"score_spread":0.22548446609669467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W585122078","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981276,0.000054091644,0.0004985421,0.000576384,0.00037450882,0.00029222592,0.000048959184,0.0000016864249,0.000026049263],"genre_scores_gemma":[0.9994023,0.000009344914,0.00029327263,0.00024045407,0.000040907256,0.0000028740653,1.3145646e-7,0.000005726033,0.000005005338],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985431,0.00016583732,0.00042960633,0.00017009284,0.0005460822,0.00014529054],"domain_scores_gemma":[0.9986593,0.00016271297,0.00080355135,0.00018958839,0.00013381838,0.00005102069],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004544194,0.000103922954,0.0001952987,0.00009649983,0.000075379896,0.000014633989,0.0005409087,0.000030987667,0.0000017567044],"category_scores_gemma":[0.0005996135,0.00005467862,0.00006642022,0.00064358517,0.00045229358,0.00028097356,0.000030254567,0.00015664654,3.9375642e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015910123,0.00058449083,0.042968176,0.00010426598,0.0000020753805,3.937187e-7,0.0003062839,0.000377849,0.9506895,0.0024489725,0.000089875444,0.0008370987],"study_design_scores_gemma":[0.0030791669,0.0023740993,0.67824167,0.00015028115,0.000008433286,0.000009385356,0.00010383658,0.00019078587,0.31445873,0.0012124798,0.000093903654,0.000077215256],"about_ca_topic_score_codex":0.0000072836788,"about_ca_topic_score_gemma":0.000014976517,"teacher_disagreement_score":0.63623077,"about_ca_system_score_codex":0.000013129275,"about_ca_system_score_gemma":0.0005053594,"threshold_uncertainty_score":0.22297294},"labels":[],"label_agreement":null},{"id":"W591490378","doi":"10.71781/28918","title":"Contrôle de la réponse immunitaire par l’indoleamine 2,3-dioxygénase : étude de la régulation d’une molécule immuno-suppressive dans les cellules cancéreuses et les lymphocytes B chez l’humain","year":2010,"lang":"fr","type":"dissertation","venue":"Open MIND","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Multiple Sclerosis Society of Canada; Canadian Institutes of Health Research; Multiple Sclerosis Society; Cancer Research Society","keywords":"Molecular biology; Chemistry; Biology","score_opus":0.016141446966203433,"score_gpt":0.30092161125529815,"score_spread":0.2847801642890947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W591490378","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9819751,0.0026802917,0.00017874467,0.00033797574,0.000325011,0.0013169582,0.00053757953,0.000028672834,0.012619699],"genre_scores_gemma":[0.98959506,0.0008261541,0.0021672428,0.00014375563,0.00011602989,0.00027558964,0.0010156488,0.00018618726,0.005674355],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99270874,0.0036407663,0.0009080601,0.0011837028,0.00053486036,0.0010238418],"domain_scores_gemma":[0.99394614,0.0035826906,0.0009496676,0.0010183926,0.00019371226,0.00030939607],"candidate_categories":["metaepi_narrow","sts","scholarly_communication","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001811931,0.001001322,0.00091926067,0.00029657967,0.0015838926,0.0013679074,0.0022765961,0.0015100793,0.0018474198],"category_scores_gemma":[0.0026721503,0.0010530484,0.00033806753,0.0005566478,0.0016517291,0.0007519985,0.0004294545,0.0015762129,0.00012000526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010005389,0.0009808587,0.0031866592,0.00016969132,0.00011727054,0.00035120145,0.042192563,0.0013538068,0.9276508,0.0006702825,0.0001533105,0.022173006],"study_design_scores_gemma":[0.0037374417,0.00017254608,0.105321966,0.00077462813,0.0001586267,0.00017642058,0.03125588,0.0018309485,0.8491198,0.00026954166,0.006117986,0.0010642275],"about_ca_topic_score_codex":0.020712754,"about_ca_topic_score_gemma":0.026785988,"teacher_disagreement_score":0.1021353,"about_ca_system_score_codex":0.00034462937,"about_ca_system_score_gemma":0.0020225346,"threshold_uncertainty_score":0.9997862},"labels":[],"label_agreement":null},{"id":"W6901561438","doi":"10.60692/w6fpp-p6m20","title":"Associations between peripheral inflammation and clinical phenotypes of bipolar depression in a lower-middle income country","year":2023,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Depression (economics); Bipolar disorder; Bipolar II disorder; Socioeconomic status; Clinical trial; Randomized controlled trial; Logistic regression; Inflammation","score_opus":0.05020036085831077,"score_gpt":0.2679035428950424,"score_spread":0.21770318203673167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901561438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983347,0.0000035317132,0.00029286576,0.000026915912,0.00019686006,0.00027227608,0.00019747543,0.00015076675,0.00052460656],"genre_scores_gemma":[0.99980515,0.0000015780429,0.000033171527,0.00003005494,0.000054699092,0.000012457503,0.000029172721,0.0000069347434,0.000026780297],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998464,0.00015137969,0.0007896557,0.0001402804,0.0002803624,0.00017431933],"domain_scores_gemma":[0.99928445,0.000083916835,0.00036889597,0.00016387274,0.000046943656,0.00005190502],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054276397,0.00010372431,0.00023439685,0.00028925537,0.00009641347,0.00007394864,0.000120556906,0.00013273167,0.000005773251],"category_scores_gemma":[0.00029752916,0.00009090796,0.000043601827,0.0005761573,0.00005250296,0.00070037326,0.00007250351,0.00011157581,0.00011313555],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023112063,0.0000019795473,0.9873118,0.0001222849,0.000005982536,8.8861145e-7,0.011243533,0.00006373937,0.00005189743,0.00013009255,0.000008628336,0.0010361001],"study_design_scores_gemma":[0.00091424305,0.000030150397,0.99295086,0.00013633085,0.0000063256834,0.0000011942227,0.001468579,0.0028776657,0.0014097076,0.000007842312,0.00009202697,0.000105064384],"about_ca_topic_score_codex":0.000015093514,"about_ca_topic_score_gemma":0.0000021656194,"teacher_disagreement_score":0.009774954,"about_ca_system_score_codex":0.00005440121,"about_ca_system_score_gemma":0.00003028885,"threshold_uncertainty_score":0.3707119},"labels":[],"label_agreement":null},{"id":"W6901605494","doi":"10.60692/pw2eq-3h719","title":"Decoding the Inflammatory Signature of the Major Depressive Episode: Insights from Peripheral Immunophenotyping in Active and Remitted Condition","year":2023,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Immune system; Inflammation; FOXP3; Immunophenotyping; Acquired immune system; Innate immune system; Pathogenesis; Major depressive episode","score_opus":0.017655987979653825,"score_gpt":0.21221569491500228,"score_spread":0.19455970693534846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901605494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985223,0.000009946159,0.0001352122,0.00006738441,0.00023740575,0.00042076324,0.00006548336,0.000077520635,0.00046398753],"genre_scores_gemma":[0.9996992,4.78335e-7,0.000005470731,0.00019778509,0.000020305097,0.000044829667,0.000007645378,0.0000067285687,0.00001760122],"study_design_codex":"qualitative","study_design_gemma":"observational","domain_scores_codex":[0.99898815,0.00018392522,0.00034717456,0.00012931689,0.00021086846,0.00014054058],"domain_scores_gemma":[0.99933153,0.00008116919,0.00030094088,0.00022670241,0.000038577768,0.000021063222],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000082519575,0.000115661736,0.00013208718,0.00012963403,0.0002341368,0.00007999105,0.00021447365,0.000092887305,0.000006338604],"category_scores_gemma":[0.00012137987,0.00006828148,0.000041247273,0.00041803104,0.00009257567,0.0005912631,0.00010372462,0.0001727854,0.000026203532],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000456572,0.000006205162,0.10274753,0.0005483828,0.00007674643,0.00001311908,0.84345275,0.0017742543,0.044970535,0.0033548146,0.0001727311,0.002426342],"study_design_scores_gemma":[0.0016609546,0.000011570109,0.80079126,0.00041216094,0.000011521992,0.000007419611,0.04279847,0.009408613,0.14456116,0.000106178784,0.000044112676,0.00018659949],"about_ca_topic_score_codex":0.00001789648,"about_ca_topic_score_gemma":0.0000032249327,"teacher_disagreement_score":0.8006543,"about_ca_system_score_codex":0.00005411594,"about_ca_system_score_gemma":0.000021496917,"threshold_uncertainty_score":0.27844378},"labels":[],"label_agreement":null},{"id":"W6901663364","doi":"10.60692/7za3b-nkf58","title":"Decoding the Inflammatory Signature of the Major Depressive Episode: Insights from Peripheral Immunophenotyping in Active and Remitted Condition","year":2023,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Immune system; Inflammation; FOXP3; Immunophenotyping; Acquired immune system; Innate immune system; Pathogenesis; Major depressive episode","score_opus":0.017655987979653825,"score_gpt":0.21221569491500228,"score_spread":0.19455970693534846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901663364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985223,0.000009946159,0.0001352122,0.00006738441,0.00023740575,0.00042076324,0.00006548336,0.000077520635,0.00046398753],"genre_scores_gemma":[0.9996992,4.78335e-7,0.000005470731,0.00019778509,0.000020305097,0.000044829667,0.000007645378,0.0000067285687,0.00001760122],"study_design_codex":"qualitative","study_design_gemma":"observational","domain_scores_codex":[0.99898815,0.00018392522,0.00034717456,0.00012931689,0.00021086846,0.00014054058],"domain_scores_gemma":[0.99933153,0.00008116919,0.00030094088,0.00022670241,0.000038577768,0.000021063222],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000082519575,0.000115661736,0.00013208718,0.00012963403,0.0002341368,0.00007999105,0.00021447365,0.000092887305,0.000006338604],"category_scores_gemma":[0.00012137987,0.00006828148,0.000041247273,0.00041803104,0.00009257567,0.0005912631,0.00010372462,0.0001727854,0.000026203532],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000456572,0.000006205162,0.10274753,0.0005483828,0.00007674643,0.00001311908,0.84345275,0.0017742543,0.044970535,0.0033548146,0.0001727311,0.002426342],"study_design_scores_gemma":[0.0016609546,0.000011570109,0.80079126,0.00041216094,0.000011521992,0.000007419611,0.04279847,0.009408613,0.14456116,0.000106178784,0.000044112676,0.00018659949],"about_ca_topic_score_codex":0.00001789648,"about_ca_topic_score_gemma":0.0000032249327,"teacher_disagreement_score":0.8006543,"about_ca_system_score_codex":0.00005411594,"about_ca_system_score_gemma":0.000021496917,"threshold_uncertainty_score":0.27844378},"labels":[],"label_agreement":null},{"id":"W6901671872","doi":"10.60692/n48cg-zmk09","title":"Add-on Sodium Benzoate and N-Acetylcysteine in patients with early schizophrenia spectrum disorder: a multicentre, double-blind, randomised placebo controlled feasibility trial","year":2024,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Placebo; Clinical trial; Schizophrenia (object-oriented programming); Randomized controlled trial; Psychosis; Cognition; NMDA receptor","score_opus":0.026310186845872864,"score_gpt":0.22827047306018544,"score_spread":0.20196028621431258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901671872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897022,0.000007329446,0.00028179924,0.00007583648,0.0005335021,0.008102973,0.0001041502,0.0002936402,0.00089854206],"genre_scores_gemma":[0.999275,3.400468e-7,0.000017473934,0.000079975456,0.00005604597,0.00043137695,0.000017044138,0.000022982786,0.00009970416],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9973659,0.0002403204,0.0009664344,0.00045988467,0.000548007,0.00041945925],"domain_scores_gemma":[0.9990508,0.000107293854,0.0002917663,0.00036200514,0.00004776301,0.00014035648],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047956372,0.0003638339,0.00058583275,0.00048672923,0.00015271151,0.0006065941,0.0001854385,0.00012932441,0.000025566833],"category_scores_gemma":[0.00011341783,0.0002470114,0.000119818396,0.00047602277,0.00008063234,0.0009028286,0.000054038388,0.00022906692,0.0002389922],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9762469,0.000036803554,0.012031456,0.00029482562,0.00003308232,0.0000053470503,0.010884756,0.00008122923,0.000005894651,0.00020461885,0.000009256988,0.0001658251],"study_design_scores_gemma":[0.9839895,0.00069465203,0.009606434,0.0002765244,0.00003357846,0.0000031952293,0.0009583515,0.003505477,0.0005688907,0.0000022350812,0.000030187352,0.00033099033],"about_ca_topic_score_codex":0.000017532253,"about_ca_topic_score_gemma":0.0000067321594,"teacher_disagreement_score":0.009926405,"about_ca_system_score_codex":0.00011821591,"about_ca_system_score_gemma":0.00006674518,"threshold_uncertainty_score":0.9999982},"labels":[],"label_agreement":null},{"id":"W6901827723","doi":"10.60692/0dgc0-kf866","title":"Reliable biomarkers for decreased spatial navigation in the Young People with Obesity: Increased serum CRP and QUIN levels","year":2022,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Kynurenine; Quinolinic acid; Kynurenic acid; Obesity; Kynurenine pathway; Montreal Cognitive Assessment; Cognitive flexibility; Cognition","score_opus":0.02427669244259122,"score_gpt":0.21160369614849509,"score_spread":0.18732700370590386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901827723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940251,0.000001561029,0.0035474969,0.0001312697,0.00014550175,0.0011842117,0.0002946347,0.000082948536,0.0005872941],"genre_scores_gemma":[0.9990086,5.6470352e-8,0.000080063284,0.00039700908,0.000019092347,0.000427019,0.000035839374,0.000009892431,0.00002242384],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986685,0.00018875735,0.00033102834,0.00018987064,0.00038635885,0.00023550633],"domain_scores_gemma":[0.999423,0.000051804145,0.00020975314,0.000224287,0.00004078718,0.000050334038],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059459603,0.00014118494,0.0001501196,0.0001500662,0.00047028225,0.00019357745,0.0002051856,0.00003846258,0.000014676229],"category_scores_gemma":[0.000051056537,0.000102360085,0.000034429897,0.0004589294,0.00003615347,0.00052144454,0.000054347172,0.00009331582,0.000012709645],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011805823,0.000030058252,0.81442726,0.00076206063,0.000024650491,0.000012854988,0.18131831,0.00044633393,0.00038090933,0.00061392336,0.000269489,0.00053354463],"study_design_scores_gemma":[0.006780501,0.00035217218,0.8678538,0.00013345783,0.000028654455,0.00034635453,0.09276733,0.024752695,0.0061022183,0.000021564492,0.00039817556,0.0004630885],"about_ca_topic_score_codex":0.00027380616,"about_ca_topic_score_gemma":0.00001961976,"teacher_disagreement_score":0.088550985,"about_ca_system_score_codex":0.00009141173,"about_ca_system_score_gemma":0.000063421394,"threshold_uncertainty_score":0.41741234},"labels":[],"label_agreement":null},{"id":"W6901833030","doi":"10.60692/qv6db-zqt02","title":"Decoding the inflammatory signature of the major depressive episode: insights from peripheral immunophenotyping in active and remitted condition, a case–control study","year":2024,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Monocytosis; Immunophenotyping; Pathogenesis; FOXP3; Immune system; Major depressive episode; CD69; Depression (economics); Monocyte","score_opus":0.013133595638180853,"score_gpt":0.21611698866559975,"score_spread":0.2029833930274189,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901833030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976897,0.00006544378,0.00045315182,0.000048728278,0.0003071587,0.0010015992,0.00015779643,0.00007052931,0.00020588016],"genre_scores_gemma":[0.9996795,1.608475e-7,0.0000041209187,0.00017530983,0.00002909458,0.0000914132,0.0000014992133,0.000008808135,0.000010079066],"study_design_codex":"qualitative","study_design_gemma":"observational","domain_scores_codex":[0.9986761,0.00034364135,0.00044695768,0.00017960434,0.00021553776,0.0001381143],"domain_scores_gemma":[0.9993165,0.00014028577,0.00021196272,0.00025794233,0.00004791141,0.000025361636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001238184,0.00015089223,0.00017286866,0.00013530535,0.00025968323,0.00019961214,0.00019243476,0.000081429425,0.000010838946],"category_scores_gemma":[0.00010269341,0.000084772524,0.000051115956,0.00031812544,0.000085032276,0.00071926543,0.000073111834,0.00024449814,0.000010386546],"study_design_candidate":"qualitative","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030555233,0.000011964719,0.056320995,0.00039659065,0.00017498276,0.0002028874,0.9353045,0.00056364737,0.0038657968,0.0011085719,0.00003130071,0.0017132107],"study_design_scores_gemma":[0.00580024,0.00007608117,0.66980946,0.0010986805,0.000119653676,0.00035597137,0.26039487,0.030973364,0.030757615,0.00010296915,0.000042979864,0.00046810566],"about_ca_topic_score_codex":0.000039813698,"about_ca_topic_score_gemma":0.000013270696,"teacher_disagreement_score":0.67490965,"about_ca_system_score_codex":0.00007538942,"about_ca_system_score_gemma":0.000035543897,"threshold_uncertainty_score":0.34569234},"labels":[],"label_agreement":null},{"id":"W6901971366","doi":"10.60692/xje2n-0jk28","title":"Decoding the inflammatory signature of the major depressive episode: insights from peripheral immunophenotyping in active and remitted condition, a case–control study","year":2024,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Monocytosis; Immunophenotyping; Pathogenesis; FOXP3; Immune system; Major depressive episode; CD69; Depression (economics); Monocyte","score_opus":0.013133595638180853,"score_gpt":0.21611698866559975,"score_spread":0.2029833930274189,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901971366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976897,0.00006544378,0.00045315182,0.000048728278,0.0003071587,0.0010015992,0.00015779643,0.00007052931,0.00020588016],"genre_scores_gemma":[0.9996795,1.608475e-7,0.0000041209187,0.00017530983,0.00002909458,0.0000914132,0.0000014992133,0.000008808135,0.000010079066],"study_design_codex":"qualitative","study_design_gemma":"observational","domain_scores_codex":[0.9986761,0.00034364135,0.00044695768,0.00017960434,0.00021553776,0.0001381143],"domain_scores_gemma":[0.9993165,0.00014028577,0.00021196272,0.00025794233,0.00004791141,0.000025361636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001238184,0.00015089223,0.00017286866,0.00013530535,0.00025968323,0.00019961214,0.00019243476,0.000081429425,0.000010838946],"category_scores_gemma":[0.00010269341,0.000084772524,0.000051115956,0.00031812544,0.000085032276,0.00071926543,0.000073111834,0.00024449814,0.000010386546],"study_design_candidate":"qualitative","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030555233,0.000011964719,0.056320995,0.00039659065,0.00017498276,0.0002028874,0.9353045,0.00056364737,0.0038657968,0.0011085719,0.00003130071,0.0017132107],"study_design_scores_gemma":[0.00580024,0.00007608117,0.66980946,0.0010986805,0.000119653676,0.00035597137,0.26039487,0.030973364,0.030757615,0.00010296915,0.000042979864,0.00046810566],"about_ca_topic_score_codex":0.000039813698,"about_ca_topic_score_gemma":0.000013270696,"teacher_disagreement_score":0.67490965,"about_ca_system_score_codex":0.00007538942,"about_ca_system_score_gemma":0.000035543897,"threshold_uncertainty_score":0.34569234},"labels":[],"label_agreement":null},{"id":"W6902062074","doi":"10.6084/m9.figshare.26717244.v1","title":"Additional file 2 of Impact of maternal immune activation and sex on placental and fetal brain cytokine and gene expression profiles in a preclinical model of neurodevelopmental disorders","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Immune system; Gene expression; Cytokine; Fetus; Placenta; Gene; Pregnancy","score_opus":0.035622071892025424,"score_gpt":0.2894897841386092,"score_spread":0.2538677122465838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902062074","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.47011054,0.000014827169,4.5714316e-7,0.000012745383,0.0000034223885,0.00011421677,0.52967525,0.0000071384707,0.00006141171],"genre_scores_gemma":[0.9491376,0.0000071955687,0.00015078747,0.00001638802,0.0000065910112,0.00006332026,0.05054889,0.00001141253,0.000057811827],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992464,0.00003820886,0.00021729327,0.00024630383,0.00015362185,0.00009812571],"domain_scores_gemma":[0.9989392,0.00087175565,0.00008953803,0.00005777686,0.000007741729,0.00003396255],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000021105214,0.00010616182,0.00014437197,0.00010373732,0.000021891592,0.00001467818,0.000057179554,0.000052640848,0.12408091],"category_scores_gemma":[0.00080173806,0.0000889228,0.000036580554,0.00009256849,0.000048630238,0.00016350677,0.0001035955,0.00009880612,0.0000023003877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033800086,0.00020652887,0.0003153839,0.0004917496,0.000010264052,0.0000037708576,0.00041891393,0.00017294833,0.7732101,0.000005024554,0.21704982,0.0077774553],"study_design_scores_gemma":[0.0012129861,0.0004956662,0.3073197,0.005072185,0.000002243748,0.000021758475,0.00008007749,0.046458725,0.63843894,0.00017358345,0.0004874195,0.00023673606],"about_ca_topic_score_codex":0.000004407133,"about_ca_topic_score_gemma":0.0000017737794,"teacher_disagreement_score":0.47912633,"about_ca_system_score_codex":0.000013481505,"about_ca_system_score_gemma":0.00006501982,"threshold_uncertainty_score":0.8767198},"labels":[],"label_agreement":null},{"id":"W6902442735","doi":"10.6084/m9.figshare.8142533","title":"Additional file 2: of Insights on multimorbidity and associated health service use and costs from three population-based studies of older adults in Ontario with diabetes, dementia and stroke","year":2019,"lang":"en","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Multimorbidity; Dementia; Stroke (engine); Health services; MEDLINE; Service (business); Comorbidity","score_opus":0.0461975501646193,"score_gpt":0.24306453390734373,"score_spread":0.19686698374272443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902442735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5232617,0.00003912963,5.805318e-9,0.000009253611,0.0000037420757,0.00016450138,0.47651157,0.0000047310873,0.0000053277936],"genre_scores_gemma":[0.81701267,0.0000010472196,0.000050314837,0.0003336461,0.0000019952395,0.000044327327,0.18254057,0.000005778078,0.00000964374],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993093,0.000048984253,0.00013825895,0.00024057606,0.00015781564,0.0001050687],"domain_scores_gemma":[0.99782354,0.0018199639,0.00017245152,0.00008576677,0.000059916718,0.000038353362],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000011824499,0.00009746229,0.0001865565,0.000053525993,0.000039771163,0.000013924767,0.000041780466,0.000038851627,0.14392887],"category_scores_gemma":[0.0007794409,0.00008263547,0.000009994489,0.000086590895,0.000012195794,0.00013254328,0.00003773155,0.00008404426,0.000005453707],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022861715,0.0005040371,0.7443638,0.00054216344,0.00008290376,0.0000039326246,0.001785055,0.000055670247,0.00028613955,0.0000037703674,0.2511219,0.0010220093],"study_design_scores_gemma":[0.0012430925,0.00012933117,0.99337864,0.0037933404,0.0000022985714,4.5672948e-8,0.000047078847,0.0006827418,0.0003285613,0.000006083783,0.0003068642,0.00008193609],"about_ca_topic_score_codex":0.004464514,"about_ca_topic_score_gemma":0.37674257,"teacher_disagreement_score":0.37227806,"about_ca_system_score_codex":0.00004238751,"about_ca_system_score_gemma":0.00006727993,"threshold_uncertainty_score":0.8568537},"labels":[],"label_agreement":null},{"id":"W6902446804","doi":"10.6084/m9.figshare.28252208","title":"Additional file 1 of Do individuals with inflammatory arthritis receive minimally adequate treatment for incident depression and anxiety: A population-based study","year":2025,"lang":"en","type":"article","venue":"Open MIND","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"British Columbia Centre on Substance Use; University of British Columbia","funders":"","keywords":"Depression (economics); Inflammatory arthritis; Rheumatoid arthritis; Arthritis; MEDLINE","score_opus":0.0227778368990866,"score_gpt":0.2878857038766874,"score_spread":0.2651078669776008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902446804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9159003,0.00002456753,0.0000074730137,0.000043219396,0.00001842236,0.0016868317,0.08139854,0.0000028677453,0.0009177839],"genre_scores_gemma":[0.9908222,0.000004387727,0.0033403765,0.0000753609,0.000010145478,0.0016264258,0.0032177158,0.000010475265,0.0008929438],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9990515,0.000075056945,0.00020764908,0.00038045892,0.00016123371,0.0001240902],"domain_scores_gemma":[0.99854493,0.0010689296,0.00014936502,0.00015909271,0.000034286688,0.000043378142],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006252364,0.0001200629,0.00017289663,0.00009269542,0.00013421218,0.00009310233,0.00015394622,0.000037542068,0.07528195],"category_scores_gemma":[0.00034500085,0.00009692029,0.000029326857,0.00014572986,0.000044757682,0.00014687928,0.000065947694,0.00003423981,0.000010038884],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012082215,0.0018917443,0.10284898,0.00002931999,0.00009805185,0.000024771016,0.0020647661,0.00008930043,0.0018672295,0.000027654687,0.10029213,0.7895578],"study_design_scores_gemma":[0.00860452,0.0017677984,0.82723415,0.0008955582,0.00004524431,0.0000047045614,0.001876901,0.00016652065,0.027101817,0.00020286861,0.13172808,0.0003718547],"about_ca_topic_score_codex":0.000019671583,"about_ca_topic_score_gemma":0.0003053876,"teacher_disagreement_score":0.789186,"about_ca_system_score_codex":0.000030949468,"about_ca_system_score_gemma":0.00018974316,"threshold_uncertainty_score":0.9255634},"labels":[],"label_agreement":null},{"id":"W6902471879","doi":"10.6084/m9.figshare.26586243","title":"Additional file 1 of First trimester human umbilical cord perivascular cells (HUCPVC) modulate the kynurenine pathway and glutamate neurotransmission in an LPS-induced mouse model of neuroinflammation","year":2024,"lang":"en","type":"article","venue":"Open MIND","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; CReATe Fertility Centre","funders":"","keywords":"Neuroinflammation; Kynurenine pathway; Umbilical cord; Glutamate receptor; Neurotransmission; Microglia; Kynurenine; First trimester","score_opus":0.05599033859134534,"score_gpt":0.28488166850059266,"score_spread":0.22889132990924732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902471879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98300874,0.0000051835173,0.000010583483,0.00013415747,0.000022480279,0.0005038762,0.01585471,0.0000054326943,0.00045485416],"genre_scores_gemma":[0.9981584,0.000005480233,0.00029344295,0.000028508031,0.000014605837,0.00005598672,0.00063468097,0.00002340267,0.00078547787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986736,0.0001464,0.00033760056,0.00044319636,0.00023812911,0.00016104607],"domain_scores_gemma":[0.99915683,0.00037855428,0.000081287144,0.00029591657,0.000022157215,0.00006523998],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011788219,0.00014661341,0.00019219371,0.000091426446,0.00009616768,0.00012803763,0.00036549458,0.00006739859,0.039103936],"category_scores_gemma":[0.00011752504,0.000110771034,0.000068458634,0.00020749896,0.00012950617,0.00039270916,0.00011754074,0.00016600192,0.000019390176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007561363,0.000116264404,0.0000013177588,0.000038279068,0.0000024661908,0.000008926048,0.0005522614,0.0010066141,0.9850498,0.000019503552,0.0023310315,0.010797935],"study_design_scores_gemma":[0.00050092814,0.00028247718,0.00059005665,0.00015067136,0.000006325269,0.000006637725,0.00004011363,0.17975241,0.8130996,0.0001773092,0.0052451245,0.00014834064],"about_ca_topic_score_codex":0.000013200708,"about_ca_topic_score_gemma":0.000045795965,"teacher_disagreement_score":0.17874579,"about_ca_system_score_codex":0.00000888613,"about_ca_system_score_gemma":0.00006941457,"threshold_uncertainty_score":0.96177447},"labels":[],"label_agreement":null},{"id":"W6907816221","doi":"10.25384/sage.25309084","title":"sj-docx-1-cpa-10.1177_07067437241234954 - Supplemental material for Patient Perceptions of Microbiome-Based Therapies as Novel Treatments for Mood Disorders: A Mixed Methods Study","year":2024,"lang":"en","type":"article","venue":"Sage Journals Data","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Mood; Perception; MEDLINE; Affect (linguistics); Mood disorders; Randomized controlled trial","score_opus":0.064097334504495,"score_gpt":0.3965422837699719,"score_spread":0.3324449492654769,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6907816221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7843093,0.0011955835,0.052042175,0.0016212085,0.0018175936,0.005065012,0.15371569,0.00014602559,0.00008742544],"genre_scores_gemma":[0.9668069,0.0003305106,0.029302564,0.00020617152,0.00016225148,0.0003693819,0.002363568,0.0000957175,0.00036292695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975229,0.000266286,0.00066291715,0.00077507575,0.00030177692,0.0004710517],"domain_scores_gemma":[0.9981866,0.0006700983,0.00021474119,0.00077245454,0.000046903955,0.00010919712],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006459392,0.00033618184,0.0003951144,0.0003135443,0.00032560094,0.0003542861,0.0008693596,0.000074322925,0.007157229],"category_scores_gemma":[0.00023856999,0.00027123044,0.00024360069,0.00037343462,0.00013637784,0.00054147857,0.0002902036,0.0001125902,0.000016930868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039767442,0.0027950585,0.00008536244,0.000083661704,0.00025722384,0.0000028338804,0.0017058448,0.0000059536046,0.89439327,0.000012241471,0.010123056,0.09013785],"study_design_scores_gemma":[0.023050625,0.009366037,0.0036055865,0.0008363881,0.0010899642,0.00007074061,0.030694494,0.0035119804,0.82458365,0.00268634,0.09905022,0.0014539968],"about_ca_topic_score_codex":0.000058192647,"about_ca_topic_score_gemma":0.00012537824,"teacher_disagreement_score":0.1824976,"about_ca_system_score_codex":0.00007331588,"about_ca_system_score_gemma":0.00016125283,"threshold_uncertainty_score":0.999974},"labels":[],"label_agreement":null},{"id":"W6913037174","doi":"10.5281/zenodo.7716582","title":"Mechanistic convergence of depression and suicidality on astrocyte fatty acid metabolism","year":2023,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Astrocyte; Convergence (economics); Depression (economics); Metabolism; Fatty acid; Fatty acid metabolism","score_opus":0.049210804093985726,"score_gpt":0.26748919484691075,"score_spread":0.21827839075292502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6913037174","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96666414,0.0000614731,0.0046999855,0.00044139536,0.00021763874,0.0005395268,0.00034612932,0.0012013968,0.025828345],"genre_scores_gemma":[0.99911,0.000108064436,0.000059903752,0.00013958912,0.000025988225,4.0301266e-8,0.00007685241,0.00031331327,0.00016623583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847245,0.0003050261,0.00017812551,0.00041621012,0.00035729792,0.00027086295],"domain_scores_gemma":[0.99932605,0.000057988924,0.00008635221,0.00030404286,0.00010429305,0.000121251265],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00035957666,0.00010992106,0.0001321833,0.00017927706,0.000860357,0.00014552218,0.00051757344,0.00004192191,0.0021760885],"category_scores_gemma":[0.0015045634,0.00010519688,0.00003372933,0.00064043887,0.00018855884,0.00013354358,0.00068366644,0.00015160067,0.0021898774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013285357,0.00007838722,0.000008199922,0.0000635422,0.000006792424,0.000011358485,0.00044483243,0.000032901207,0.9463016,0.015704788,0.00683045,0.03038432],"study_design_scores_gemma":[0.0008223531,0.00020983774,0.0107700545,0.00003567985,0.000009160271,0.000030529925,0.00025545934,0.0011104606,0.86352426,0.0014444782,0.121582165,0.00020557703],"about_ca_topic_score_codex":0.000006199199,"about_ca_topic_score_gemma":1.2758538e-7,"teacher_disagreement_score":0.11475172,"about_ca_system_score_codex":0.000019691974,"about_ca_system_score_gemma":0.0000024065096,"threshold_uncertainty_score":0.9987361},"labels":[],"label_agreement":null},{"id":"W6920461918","doi":"10.60692/eaxm1-ews33","title":"Add-on Sodium Benzoate and N-Acetylcysteine in patients with early schizophrenia spectrum disorder: a multicentre, double-blind, randomised placebo controlled feasibility trial","year":2024,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Placebo; Clinical trial; Schizophrenia (object-oriented programming); Randomized controlled trial; Psychosis; Cognition; NMDA receptor","score_opus":0.026310186845872864,"score_gpt":0.22827047306018544,"score_spread":0.20196028621431258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920461918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897022,0.000007329446,0.00028179924,0.00007583648,0.0005335021,0.008102973,0.0001041502,0.0002936402,0.00089854206],"genre_scores_gemma":[0.999275,3.400468e-7,0.000017473934,0.000079975456,0.00005604597,0.00043137695,0.000017044138,0.000022982786,0.00009970416],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9973659,0.0002403204,0.0009664344,0.00045988467,0.000548007,0.00041945925],"domain_scores_gemma":[0.9990508,0.000107293854,0.0002917663,0.00036200514,0.00004776301,0.00014035648],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047956372,0.0003638339,0.00058583275,0.00048672923,0.00015271151,0.0006065941,0.0001854385,0.00012932441,0.000025566833],"category_scores_gemma":[0.00011341783,0.0002470114,0.000119818396,0.00047602277,0.00008063234,0.0009028286,0.000054038388,0.00022906692,0.0002389922],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9762469,0.000036803554,0.012031456,0.00029482562,0.00003308232,0.0000053470503,0.010884756,0.00008122923,0.000005894651,0.00020461885,0.000009256988,0.0001658251],"study_design_scores_gemma":[0.9839895,0.00069465203,0.009606434,0.0002765244,0.00003357846,0.0000031952293,0.0009583515,0.003505477,0.0005688907,0.0000022350812,0.000030187352,0.00033099033],"about_ca_topic_score_codex":0.000017532253,"about_ca_topic_score_gemma":0.0000067321594,"teacher_disagreement_score":0.009926405,"about_ca_system_score_codex":0.00011821591,"about_ca_system_score_gemma":0.00006674518,"threshold_uncertainty_score":0.9999982},"labels":[],"label_agreement":null},{"id":"W6920525778","doi":"10.6084/m9.figshare.19518345.v1","title":"Additional file 1 of Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior","year":2022,"lang":"en","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Gating; Flow cytometry; Population; Myeloid; Autofluorescence; Antibody; Phenotype; Cell; Cell type","score_opus":0.057148945868602925,"score_gpt":0.27211921640617776,"score_spread":0.21497027053757484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920525778","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23612691,0.000033028955,4.0762265e-9,0.00013408979,0.0000054575385,0.0004746049,0.7631426,0.000010412525,0.00007287928],"genre_scores_gemma":[0.84305686,0.0000018687098,0.000019888646,0.0013179865,0.0000081819635,0.0050295703,0.15025163,0.000015952748,0.00029805792],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99919194,0.00008975203,0.00013404615,0.0002310106,0.00021389629,0.00013933217],"domain_scores_gemma":[0.99907917,0.00065736845,0.00009841878,0.00010209319,0.000023132676,0.00003983678],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000020785743,0.00009423488,0.00012510925,0.00006121043,0.00009965382,0.0000150497335,0.00012673376,0.000022661998,0.6915694],"category_scores_gemma":[0.00056326407,0.00007733389,0.000021903717,0.00031603716,0.000029004686,0.000054978653,0.0001684241,0.00008172764,0.000006651444],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055298624,0.0001499542,0.000031962005,0.000008914383,0.0000038058188,0.000009049559,0.0005158677,0.000006215569,0.012241033,0.000004813709,0.98655635,0.00041673402],"study_design_scores_gemma":[0.0019216556,0.0013546621,0.18857603,0.0007749093,0.0000071559257,0.000055394037,0.0020062902,0.0002095097,0.19791944,0.000021695247,0.6067494,0.0004038611],"about_ca_topic_score_codex":0.00001191874,"about_ca_topic_score_gemma":0.000028452443,"teacher_disagreement_score":0.6915627,"about_ca_system_score_codex":0.00003514525,"about_ca_system_score_gemma":0.000040073457,"threshold_uncertainty_score":0.31535846},"labels":[],"label_agreement":null},{"id":"W6920598458","doi":"10.60692/xmz1y-f2472","title":"Associations between peripheral inflammation and clinical phenotypes of bipolar depression in a lower-middle income country","year":2023,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Depression (economics); Bipolar disorder; Bipolar II disorder; Socioeconomic status; Clinical trial; Randomized controlled trial; Logistic regression; Inflammation","score_opus":0.05020036085831077,"score_gpt":0.2679035428950424,"score_spread":0.21770318203673167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920598458","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983347,0.0000035317132,0.00029286576,0.000026915912,0.00019686006,0.00027227608,0.00019747543,0.00015076675,0.00052460656],"genre_scores_gemma":[0.99980515,0.0000015780429,0.000033171527,0.00003005494,0.000054699092,0.000012457503,0.000029172721,0.0000069347434,0.000026780297],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998464,0.00015137969,0.0007896557,0.0001402804,0.0002803624,0.00017431933],"domain_scores_gemma":[0.99928445,0.000083916835,0.00036889597,0.00016387274,0.000046943656,0.00005190502],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054276397,0.00010372431,0.00023439685,0.00028925537,0.00009641347,0.00007394864,0.000120556906,0.00013273167,0.000005773251],"category_scores_gemma":[0.00029752916,0.00009090796,0.000043601827,0.0005761573,0.00005250296,0.00070037326,0.00007250351,0.00011157581,0.00011313555],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023112063,0.0000019795473,0.9873118,0.0001222849,0.000005982536,8.8861145e-7,0.011243533,0.00006373937,0.00005189743,0.00013009255,0.000008628336,0.0010361001],"study_design_scores_gemma":[0.00091424305,0.000030150397,0.99295086,0.00013633085,0.0000063256834,0.0000011942227,0.001468579,0.0028776657,0.0014097076,0.000007842312,0.00009202697,0.000105064384],"about_ca_topic_score_codex":0.000015093514,"about_ca_topic_score_gemma":0.0000021656194,"teacher_disagreement_score":0.009774954,"about_ca_system_score_codex":0.00005440121,"about_ca_system_score_gemma":0.00003028885,"threshold_uncertainty_score":0.3707119},"labels":[],"label_agreement":null},{"id":"W6920602554","doi":"10.60692/4sn78-xw598","title":"A randomised double-blind placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at risk Mental States: The NAYAB study","year":2024,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Minocycline; Psychosis; Polyunsaturated fatty acid; At risk mental state; Mental state; Clinical trial","score_opus":0.06038752135438836,"score_gpt":0.2981503204086602,"score_spread":0.23776279905427183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920602554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97859466,0.0000067560236,0.00067232654,0.000095833224,0.0006893936,0.018983314,0.0005128015,0.00012928061,0.00031561052],"genre_scores_gemma":[0.99501693,0.0000016126006,0.000024684863,0.000093669594,0.00007994799,0.0038894215,0.000019783962,0.000016082984,0.00085788383],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99781424,0.0002480654,0.0009677784,0.00029695005,0.0004007071,0.0002722828],"domain_scores_gemma":[0.99889475,0.00032743483,0.00031371485,0.00030246223,0.000050646224,0.000110973706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006891457,0.000284468,0.0005537693,0.00026447087,0.00028638178,0.000284473,0.0001876905,0.0000692336,0.00002705309],"category_scores_gemma":[0.00013240948,0.00014644093,0.00021718479,0.00026933188,0.000053755462,0.00033522397,0.00007331272,0.00006296357,0.00011992994],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.86114216,0.000045449415,0.00022035102,0.0001033806,0.00016512818,0.0000026024832,0.13753916,0.000066310946,0.000050738134,0.000017866341,0.000057850102,0.000589021],"study_design_scores_gemma":[0.94939864,0.003085144,0.00008909181,0.000056841902,0.00016823343,0.000015497093,0.031556915,0.0048611346,0.010026114,0.000001220098,0.00055075815,0.00019039061],"about_ca_topic_score_codex":0.000016323147,"about_ca_topic_score_gemma":0.00000591993,"teacher_disagreement_score":0.105982244,"about_ca_system_score_codex":0.00015603619,"about_ca_system_score_gemma":0.00007318483,"threshold_uncertainty_score":0.59716874},"labels":[],"label_agreement":null},{"id":"W6920690325","doi":"10.60692/tc56k-86x18","title":"A randomised double-blind placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at risk Mental States: The NAYAB study","year":2024,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Minocycline; Psychosis; Polyunsaturated fatty acid; At risk mental state; Mental state; Clinical trial","score_opus":0.06038752135438836,"score_gpt":0.2981503204086602,"score_spread":0.23776279905427183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920690325","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97859466,0.0000067560236,0.00067232654,0.000095833224,0.0006893936,0.018983314,0.0005128015,0.00012928061,0.00031561052],"genre_scores_gemma":[0.99501693,0.0000016126006,0.000024684863,0.000093669594,0.00007994799,0.0038894215,0.000019783962,0.000016082984,0.00085788383],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99781424,0.0002480654,0.0009677784,0.00029695005,0.0004007071,0.0002722828],"domain_scores_gemma":[0.99889475,0.00032743483,0.00031371485,0.00030246223,0.000050646224,0.000110973706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006891457,0.000284468,0.0005537693,0.00026447087,0.00028638178,0.000284473,0.0001876905,0.0000692336,0.00002705309],"category_scores_gemma":[0.00013240948,0.00014644093,0.00021718479,0.00026933188,0.000053755462,0.00033522397,0.00007331272,0.00006296357,0.00011992994],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.86114216,0.000045449415,0.00022035102,0.0001033806,0.00016512818,0.0000026024832,0.13753916,0.000066310946,0.000050738134,0.000017866341,0.000057850102,0.000589021],"study_design_scores_gemma":[0.94939864,0.003085144,0.00008909181,0.000056841902,0.00016823343,0.000015497093,0.031556915,0.0048611346,0.010026114,0.000001220098,0.00055075815,0.00019039061],"about_ca_topic_score_codex":0.000016323147,"about_ca_topic_score_gemma":0.00000591993,"teacher_disagreement_score":0.105982244,"about_ca_system_score_codex":0.00015603619,"about_ca_system_score_gemma":0.00007318483,"threshold_uncertainty_score":0.59716874},"labels":[],"label_agreement":null},{"id":"W6920847519","doi":"10.6084/m9.figshare.26717241","title":"Additional file 1 of Impact of maternal immune activation and sex on placental and fetal brain cytokine and gene expression profiles in a preclinical model of neurodevelopmental disorders","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Immune system; Gene expression; Cytokine; Fetus; Placenta; Gene; Pregnancy","score_opus":0.036775481866537424,"score_gpt":0.29002724199893604,"score_spread":0.2532517601323986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920847519","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4697709,0.000014590694,4.650362e-7,0.000012777438,0.00000339782,0.0001141604,0.5300165,0.000007125248,0.000060077364],"genre_scores_gemma":[0.9493356,0.000007028774,0.00015370993,0.000016380109,0.0000065030968,0.000064384934,0.050347354,0.000011421693,0.000057618723],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992463,0.000038220303,0.00021720721,0.00024646707,0.00015365581,0.00009815767],"domain_scores_gemma":[0.9989282,0.00088277546,0.000089426765,0.000057874633,0.000007756916,0.000033966688],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000021207568,0.000106191656,0.00014434074,0.00010379738,0.000021890173,0.000014650084,0.000057207693,0.000052640582,0.12591961],"category_scores_gemma":[0.0008103816,0.0000889485,0.000036586807,0.00009263213,0.00004863083,0.00016340782,0.00010360838,0.000098826225,0.0000023222976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033287442,0.00020247596,0.00031803414,0.0004781335,0.000010059648,0.0000036086492,0.0004102689,0.00016878886,0.77497256,0.000004849196,0.21565868,0.0074396525],"study_design_scores_gemma":[0.0011969055,0.00049198,0.30909136,0.00509068,0.0000022345446,0.000021557598,0.000080217775,0.046391133,0.63675934,0.00017111475,0.00046801244,0.0002354471],"about_ca_topic_score_codex":0.0000043682526,"about_ca_topic_score_gemma":0.0000017645531,"teacher_disagreement_score":0.47966915,"about_ca_system_score_codex":0.000013478094,"about_ca_system_score_gemma":0.0000652766,"threshold_uncertainty_score":0.8748794},"labels":[],"label_agreement":null},{"id":"W6920908304","doi":"10.6084/m9.figshare.26717244","title":"Additional file 2 of Impact of maternal immune activation and sex on placental and fetal brain cytokine and gene expression profiles in a preclinical model of neurodevelopmental disorders","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Immune system; Gene expression; Cytokine; Fetus; Placenta; Gene; Pregnancy","score_opus":0.035622071892025424,"score_gpt":0.2894897841386092,"score_spread":0.2538677122465838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920908304","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.47011054,0.000014827169,4.5714316e-7,0.000012745383,0.0000034223885,0.00011421677,0.52967525,0.0000071384707,0.00006141171],"genre_scores_gemma":[0.9491376,0.0000071955687,0.00015078747,0.00001638802,0.0000065910112,0.00006332026,0.05054889,0.00001141253,0.000057811827],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992464,0.00003820886,0.00021729327,0.00024630383,0.00015362185,0.00009812571],"domain_scores_gemma":[0.9989392,0.00087175565,0.00008953803,0.00005777686,0.000007741729,0.00003396255],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000021105214,0.00010616182,0.00014437197,0.00010373732,0.000021891592,0.00001467818,0.000057179554,0.000052640848,0.12408091],"category_scores_gemma":[0.00080173806,0.0000889228,0.000036580554,0.00009256849,0.000048630238,0.00016350677,0.0001035955,0.00009880612,0.0000023003877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033800086,0.00020652887,0.0003153839,0.0004917496,0.000010264052,0.0000037708576,0.00041891393,0.00017294833,0.7732101,0.000005024554,0.21704982,0.0077774553],"study_design_scores_gemma":[0.0012129861,0.0004956662,0.3073197,0.005072185,0.000002243748,0.000021758475,0.00008007749,0.046458725,0.63843894,0.00017358345,0.0004874195,0.00023673606],"about_ca_topic_score_codex":0.000004407133,"about_ca_topic_score_gemma":0.0000017737794,"teacher_disagreement_score":0.47912633,"about_ca_system_score_codex":0.000013481505,"about_ca_system_score_gemma":0.00006501982,"threshold_uncertainty_score":0.8767198},"labels":[],"label_agreement":null},{"id":"W6921954257","doi":"10.11886/scjsws20221008001","title":"Improvement of cognitive function by escitalopram and paroxetine in patients with first-episode depressive disorder and its relationship with thyroid hormone levels","year":2023,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Escitalopram; Paroxetine; Major depressive disorder; Thyroid function; Thyroid; Depression (economics); Thyroid function tests; Cognition","score_opus":0.10800338666240897,"score_gpt":0.42061336697379653,"score_spread":0.31260998031138754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6921954257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99526983,0.0030368625,0.0001425804,0.000109154236,0.000045700137,0.0009763702,0.00017484855,0.000025552248,0.00021907873],"genre_scores_gemma":[0.9980194,0.0016177493,0.000010864542,0.000108170556,0.00000942993,0.00008354558,0.000022687833,0.000034728495,0.000093453935],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998069,0.00012895395,0.0004548716,0.00050394126,0.0005454377,0.00029781237],"domain_scores_gemma":[0.99806523,0.00090449816,0.0005687818,0.00015743371,0.00016686751,0.00013721423],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003041904,0.0002531566,0.00039890636,0.0004824567,0.0002335853,0.00025685856,0.00039548217,0.00006947429,0.00014147138],"category_scores_gemma":[0.0008691473,0.00019528338,0.000029200864,0.0012197124,0.00020958802,0.0015841718,0.00034243683,0.00025058564,0.0000023834068],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012677159,0.00035887773,0.96190095,0.000077698875,0.00004569783,0.000006553621,0.0002574331,0.000093644856,0.031968236,0.000024845167,0.00094621914,0.0030521352],"study_design_scores_gemma":[0.0038575279,0.00021538338,0.97121984,0.00032495058,0.00004131716,0.0000013571911,0.00016676415,0.000075524214,0.023199357,0.0005987823,0.000036804944,0.00026241565],"about_ca_topic_score_codex":0.00018352235,"about_ca_topic_score_gemma":0.00021994545,"teacher_disagreement_score":0.009318872,"about_ca_system_score_codex":0.000021566384,"about_ca_system_score_gemma":0.000036326674,"threshold_uncertainty_score":0.79634255},"labels":[],"label_agreement":null},{"id":"W6923616881","doi":"10.1371/journal.pone.0295328.s001","title":"PRISMA-P checklist.","year":2023,"lang":"en","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Funnel plot; Anxiety; Epilepsy; Publication bias; Cohort; Meta-analysis; Mental health","score_opus":0.07057460188221178,"score_gpt":0.287630425018364,"score_spread":0.21705582313615224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6923616881","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09327586,0.00016254731,0.000001409054,0.0031438367,0.00065401563,0.0010772098,0.40359816,0.0059342366,0.49215272],"genre_scores_gemma":[0.95245117,0.0000059593067,0.000014314127,0.003142809,0.00018055367,0.000196852,0.019837508,0.00004527333,0.024125557],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.999348,0.000018387744,0.00006756025,0.00021108553,0.0001428478,0.00021215704],"domain_scores_gemma":[0.9996315,0.000117891606,0.00002382556,0.00016515901,0.000009400423,0.000052190306],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000014308584,0.00006754992,0.000053569373,0.000055727483,0.000076009805,0.00004091777,0.00022142676,0.000038198716,0.15669699],"category_scores_gemma":[0.0021143404,0.00006281478,0.00004164566,0.0004926521,0.0000056054387,0.00007892772,0.000094710565,0.00007511563,0.067829035],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000014417197,0.00000786638,0.0000031710326,0.000023612303,4.127075e-7,0.000030835992,0.00006932179,0.000004344744,0.010325439,0.000075602584,0.98686856,0.0025894041],"study_design_scores_gemma":[0.00015390948,0.000011843661,0.0037229056,0.00008549667,3.157246e-7,0.0000039109655,0.000025404282,0.0002775435,0.11170141,0.00027169794,0.8836281,0.00011747943],"about_ca_topic_score_codex":5.604646e-7,"about_ca_topic_score_gemma":9.549732e-7,"teacher_disagreement_score":0.8591753,"about_ca_system_score_codex":0.000007120771,"about_ca_system_score_gemma":0.000020173777,"threshold_uncertainty_score":0.9328968},"labels":[],"label_agreement":null},{"id":"W6924426668","doi":"10.15468/dl.n6wpq8","title":"Occurrence Download","year":2023,"lang":"en","type":"dataset","venue":"Global Biodiversity Information Facility","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Download; Matching (statistics); Range (aeronautics); State (computer science)","score_opus":0.02783137682440105,"score_gpt":0.24047471523998187,"score_spread":0.21264333841558083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6924426668","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00065560645,0.0000044445846,0.0000014583388,0.0002103237,0.0009833205,0.00032919087,0.99730694,0.00032337484,0.00018531417],"genre_scores_gemma":[0.000016901276,0.000106247426,2.6717694e-7,0.0014736727,0.0000015101905,0.000004507875,0.9983964,2.034054e-8,4.6600397e-7],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981995,0.00009157107,0.00034594786,0.00034913214,0.00062396826,0.0003898391],"domain_scores_gemma":[0.99891794,0.00006845111,0.00024876936,0.000519627,0.00008028117,0.00016493352],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016198646,0.0002958187,0.0002456032,0.00012908386,0.00035032508,0.00019478351,0.00080446224,0.0003194515,0.00074424443],"category_scores_gemma":[0.000895466,0.0003023575,0.00016821653,0.0007111755,0.00027554506,0.00088979094,0.00044714374,0.00031445187,0.75896776],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034720746,0.000030384164,0.000047229623,0.00011403044,0.0000054031348,0.0000056305894,0.000026811254,0.000006428976,0.0000012527022,2.5409335e-7,0.9987999,0.00092794496],"study_design_scores_gemma":[0.00034797777,0.000027302403,0.000064234315,0.0000023901616,0.000011446912,0.0000039744223,0.000098558405,1.7322552e-7,0.00007381053,0.0000033609695,0.99906003,0.00030671852],"about_ca_topic_score_codex":0.0003427214,"about_ca_topic_score_gemma":0.000018226361,"teacher_disagreement_score":0.75822353,"about_ca_system_score_codex":0.00018438145,"about_ca_system_score_gemma":0.00012861518,"threshold_uncertainty_score":0.99994284},"labels":[],"label_agreement":null},{"id":"W6926282609","doi":"10.25318/9810010101-fra","title":"Situation de faible revenu, selon les caractéristiques de la famille économique : Canada, provinces et territoires, régions métropolitaines de recensement et agglomérations de recensement y compris les parties","year":2022,"lang":"fr","type":"dataset","venue":"Statistics Canada Dissemination","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Context (archaeology); Population; Legislation; Work (physics)","score_opus":0.016030960300758637,"score_gpt":0.28258072856049493,"score_spread":0.2665497682597363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6926282609","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03216435,0.0007889111,0.019085962,0.01165996,0.00064894155,0.0011522792,0.9342093,0.00006814649,0.00022216554],"genre_scores_gemma":[0.16112868,0.011683786,0.013366596,0.0027950334,0.00019066392,0.0011395472,0.8061438,0.00014639605,0.0034054706],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99412364,0.002738996,0.0008229036,0.00071903743,0.00066891743,0.00092649343],"domain_scores_gemma":[0.9950663,0.0031598043,0.0007364527,0.00044605767,0.00023441725,0.00035695682],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0010384473,0.00056946155,0.00045496653,0.00021041135,0.0016720963,0.0003364264,0.0005380822,0.00024801714,0.0007162741],"category_scores_gemma":[0.0036521151,0.0007002103,0.000061597515,0.0003299407,0.0003351878,0.00019511962,0.00016701837,0.0008016623,7.2412064e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.000042861742,0.00023429318,0.0012939235,0.00045992155,0.000055346267,0.00020470684,0.0014367477,0.0029300181,0.0021255724,0.013655945,0.97227615,0.0052845054],"study_design_scores_gemma":[0.0003544688,0.00019455123,0.027396275,0.00038580387,0.00016716176,0.00007256428,0.00858805,0.003949325,0.0046407194,0.0030088348,0.9503503,0.00089197006],"about_ca_topic_score_codex":0.9890114,"about_ca_topic_score_gemma":0.99948263,"teacher_disagreement_score":0.12896433,"about_ca_system_score_codex":0.010110373,"about_ca_system_score_gemma":0.013383008,"threshold_uncertainty_score":0.9996276},"labels":[],"label_agreement":null},{"id":"W6932067907","doi":"10.5683/sp3/atw6ak","title":"Supplemental data for: Randomized clinical trial of ketoprofen or ceftiofur for treatment of metritis in dairy cows","year":2024,"lang":"en","type":"dataset","venue":"Borealis","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Metritis; Ceftiofur; Ketoprofen; Randomized controlled trial; Clinical trial","score_opus":0.16200519699916982,"score_gpt":0.42918784740953897,"score_spread":0.26718265041036915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6932067907","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019414186,0.00019347684,0.000029919602,0.00029400157,0.00087035686,0.007754392,0.9906066,0.00001909092,0.000038024806],"genre_scores_gemma":[0.00014142718,0.0033352969,0.0005176956,0.000107298474,0.00037823262,0.0012196979,0.9941508,0.000035963654,0.00011358108],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961798,0.00053155405,0.0017285184,0.0009067183,0.00032005616,0.00033334515],"domain_scores_gemma":[0.99065745,0.007293121,0.0005591197,0.0013741094,0.00003746143,0.00007876584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016836034,0.00033719384,0.0019341784,0.00034822855,0.000035852467,0.00003443394,0.0010517751,0.00030757088,0.00015789701],"category_scores_gemma":[0.0064929184,0.00024027964,0.0006370451,0.00028160863,0.0003592715,0.00009252922,0.0002482697,0.00010759568,0.0000035298256],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.2628197,0.0010713384,5.6134337e-7,0.00034799424,0.00009547361,0.000012283361,0.000021017206,8.015867e-8,0.000025224599,0.0000993532,0.73275644,0.0027505131],"study_design_scores_gemma":[0.38504285,0.0015577304,0.0000011250847,0.000063920816,0.00024135929,0.0000018912048,0.000047751397,0.000046496752,0.000739657,0.00027690895,0.6118377,0.00014263028],"about_ca_topic_score_codex":0.004140489,"about_ca_topic_score_gemma":0.021062493,"teacher_disagreement_score":0.12222315,"about_ca_system_score_codex":0.000061997416,"about_ca_system_score_gemma":0.0003973426,"threshold_uncertainty_score":0.99680054},"labels":[],"label_agreement":null},{"id":"W6939706734","doi":"10.60692/qzbg6-9j718","title":"Melatonin Act as an Antidepressant via Attenuation of Neuroinflammation by Targeting Sirt1/Nrf2/HO-1 Signaling","year":2020,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Neuroinflammation; Melatonin; Luzindole; Oxidative stress; Antidepressant; Inflammation; Lipopolysaccharide; Sickness behavior","score_opus":0.03213436351021659,"score_gpt":0.2226691080200975,"score_spread":0.19053474450988092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939706734","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762493,0.0000027541994,0.021597624,0.00014446393,0.00014016562,0.00043656005,0.000054516415,0.00026799063,0.0011066268],"genre_scores_gemma":[0.9993176,2.661917e-7,0.00012663301,0.00041137612,0.000055511915,0.000015733944,0.000046695517,0.000017454107,0.000008759654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979606,0.00020550344,0.00082421006,0.00025803817,0.0005099941,0.00024161658],"domain_scores_gemma":[0.99884254,0.000030269928,0.0006696914,0.00021525747,0.000103638326,0.0001385783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027449493,0.00019698724,0.0002406201,0.00013463096,0.0001646628,0.0001619155,0.00025465316,0.000094662784,0.000039280763],"category_scores_gemma":[0.00025754323,0.0001804996,0.00007551191,0.00036263373,0.00003951031,0.001887211,0.000051827945,0.00012523726,0.00036453689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044267904,0.000018109718,0.040133897,0.0013937523,0.000033851273,0.000011803402,0.2221207,0.008623964,0.72263175,0.00091714074,0.00045883897,0.0032134948],"study_design_scores_gemma":[0.0009771783,0.00012738294,0.0033302542,0.00007365807,0.000012938222,0.000013097169,0.0055297483,0.07146376,0.9180755,0.0000048094025,0.00012875702,0.00026290558],"about_ca_topic_score_codex":0.000008812149,"about_ca_topic_score_gemma":4.0524146e-8,"teacher_disagreement_score":0.21659096,"about_ca_system_score_codex":0.000029784598,"about_ca_system_score_gemma":0.000030403271,"threshold_uncertainty_score":0.736056},"labels":[],"label_agreement":null},{"id":"W6945204469","doi":"10.25384/sage.25309087","title":"sj-docx-2-cpa-10.1177_07067437241234954 - Supplemental material for Patient Perceptions of Microbiome-Based Therapies as Novel Treatments for Mood Disorders: A Mixed Methods Study","year":2024,"lang":"en","type":"article","venue":"Sage Journals Data","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Mood; Perception; MEDLINE; Affect (linguistics); Mood disorders; Randomized controlled trial","score_opus":0.0640927075082577,"score_gpt":0.3965385619207681,"score_spread":0.3324458544125104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6945204469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7862042,0.0012211341,0.054152757,0.0016689132,0.0018514642,0.005150552,0.14951456,0.00014809013,0.0000882916],"genre_scores_gemma":[0.96643734,0.00032921592,0.029693654,0.00021033392,0.00016433891,0.00037852087,0.002314897,0.00009624963,0.00037542635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99751973,0.0002671547,0.00066352566,0.000775851,0.00030217093,0.00047158592],"domain_scores_gemma":[0.99818367,0.0006720635,0.0002148863,0.00077296793,0.00004709911,0.00010929823],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006530365,0.00033638443,0.00039549626,0.00031323556,0.00032665205,0.00035604832,0.0008693891,0.00007437588,0.0070276647],"category_scores_gemma":[0.00024198482,0.00027134345,0.00024373711,0.0003735183,0.00013632605,0.0005421719,0.0002897995,0.000112473266,0.000017049495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003978201,0.0027437173,0.00008376027,0.00008299966,0.0002558271,0.0000027888327,0.001683822,0.000005999493,0.8958538,0.000012643731,0.010003413,0.08887337],"study_design_scores_gemma":[0.022035182,0.009034045,0.0033996222,0.00080291275,0.0010499716,0.00006654174,0.028737668,0.0033661744,0.8308935,0.0025802844,0.096632995,0.0014010548],"about_ca_topic_score_codex":0.00005912766,"about_ca_topic_score_gemma":0.00012454126,"teacher_disagreement_score":0.18023314,"about_ca_system_score_codex":0.00007356277,"about_ca_system_score_gemma":0.00016424413,"threshold_uncertainty_score":0.9999739},"labels":[],"label_agreement":null},{"id":"W6958058229","doi":"10.6084/m9.figshare.16879972","title":"Additional file 2 of Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Norwegian; Depression (economics); Inflammation; Plasminogen activator; Scale (ratio); Depressive symptoms","score_opus":0.034547785324373526,"score_gpt":0.22525421813150825,"score_spread":0.19070643280713473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958058229","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08187073,0.000011724073,7.835545e-7,0.000044008862,0.000032606327,0.0001851512,0.9175205,0.00004855845,0.00028590226],"genre_scores_gemma":[0.2798816,0.000003025097,0.00015944299,0.00012911898,0.00012921714,0.0038425494,0.71351856,0.000048381993,0.0022881292],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985431,0.00010592622,0.00021790578,0.00038122805,0.0004958083,0.00025602704],"domain_scores_gemma":[0.9979923,0.0014000137,0.00029002342,0.00016026621,0.000088907815,0.000068499525],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000019844258,0.00015255962,0.00016872537,0.00006666572,0.0000876215,0.000059095877,0.00016227255,0.00010191076,0.8393433],"category_scores_gemma":[0.005505307,0.0001570465,0.000050591716,0.00033115665,0.000008836538,0.0005894293,0.00008630105,0.0002054566,0.00038631426],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035714067,0.000095229974,0.000031309264,0.0000612709,0.000012698459,0.000021572661,0.0001443099,0.00006980157,0.07300567,0.0000029894788,0.9253325,0.0011869617],"study_design_scores_gemma":[0.0010124813,0.000037168622,0.001956545,0.001150455,0.000002325816,0.000005201195,0.00008871216,0.000121896024,0.9340205,0.000016007247,0.061387517,0.00020115227],"about_ca_topic_score_codex":0.0000026801033,"about_ca_topic_score_gemma":0.000020907937,"teacher_disagreement_score":0.86394495,"about_ca_system_score_codex":0.00016352223,"about_ca_system_score_gemma":0.00022007605,"threshold_uncertainty_score":0.65907645},"labels":[],"label_agreement":null},{"id":"W6958465227","doi":"10.6084/m9.figshare.16879972.v1","title":"Additional file 2 of Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Norwegian; Depression (economics); Inflammation; Plasminogen activator; Scale (ratio); Depressive symptoms","score_opus":0.034547785324373526,"score_gpt":0.22525421813150825,"score_spread":0.19070643280713473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958465227","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08187073,0.000011724073,7.835545e-7,0.000044008862,0.000032606327,0.0001851512,0.9175205,0.00004855845,0.00028590226],"genre_scores_gemma":[0.2798816,0.000003025097,0.00015944299,0.00012911898,0.00012921714,0.0038425494,0.71351856,0.000048381993,0.0022881292],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985431,0.00010592622,0.00021790578,0.00038122805,0.0004958083,0.00025602704],"domain_scores_gemma":[0.9979923,0.0014000137,0.00029002342,0.00016026621,0.000088907815,0.000068499525],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000019844258,0.00015255962,0.00016872537,0.00006666572,0.0000876215,0.000059095877,0.00016227255,0.00010191076,0.8393433],"category_scores_gemma":[0.005505307,0.0001570465,0.000050591716,0.00033115665,0.000008836538,0.0005894293,0.00008630105,0.0002054566,0.00038631426],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035714067,0.000095229974,0.000031309264,0.0000612709,0.000012698459,0.000021572661,0.0001443099,0.00006980157,0.07300567,0.0000029894788,0.9253325,0.0011869617],"study_design_scores_gemma":[0.0010124813,0.000037168622,0.001956545,0.001150455,0.000002325816,0.000005201195,0.00008871216,0.000121896024,0.9340205,0.000016007247,0.061387517,0.00020115227],"about_ca_topic_score_codex":0.0000026801033,"about_ca_topic_score_gemma":0.000020907937,"teacher_disagreement_score":0.86394495,"about_ca_system_score_codex":0.00016352223,"about_ca_system_score_gemma":0.00022007605,"threshold_uncertainty_score":0.65907645},"labels":[],"label_agreement":null},{"id":"W6968884044","doi":"10.5281/zenodo.4394528","title":"tardis-sn/tardis: TARDIS v3.0.dev3794","year":2020,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Plotter; Merge (version control); Debugging; Plot (graphics); Code (set theory); Masking (illustration); Flowchart","score_opus":0.040657824916601325,"score_gpt":0.2462495875571702,"score_spread":0.20559176264056886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6968884044","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008058682,0.00024950915,0.0008979275,0.0014137105,0.000408158,0.00086231856,0.001393374,0.005203579,0.9894908],"genre_scores_gemma":[0.051420618,0.00212628,0.00079577405,0.0072693024,0.0030652725,6.6485745e-7,0.0054485686,0.0707543,0.85911924],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.996188,0.00061775226,0.00036699226,0.0012600651,0.00084786286,0.00071934774],"domain_scores_gemma":[0.998263,0.000043132182,0.00025802184,0.00090533897,0.00010408935,0.00042639926],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00026153406,0.00046366735,0.0004481409,0.0004535111,0.001363541,0.00091026706,0.0022974808,0.0002574992,0.11674074],"category_scores_gemma":[0.0015255157,0.00048377857,0.00021672611,0.0010040059,0.00043179805,0.00017791883,0.0019057692,0.000698628,0.07766604],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004514915,0.000105605315,3.677115e-7,0.00014241223,0.000045686058,0.00007427817,0.00047497838,0.0000065789873,0.004889541,0.0023277916,0.9669335,0.024954118],"study_design_scores_gemma":[0.0006596662,0.0001595551,0.000034552286,0.00008589603,0.000022410504,0.00006370531,0.0001728539,0.000055461416,0.0013860341,0.00015063488,0.9966851,0.0005241285],"about_ca_topic_score_codex":0.00004124026,"about_ca_topic_score_gemma":0.0000018067456,"teacher_disagreement_score":0.13037162,"about_ca_system_score_codex":0.00012351334,"about_ca_system_score_gemma":0.0000113795,"threshold_uncertainty_score":0.9999365},"labels":[],"label_agreement":null},{"id":"W6976416929","doi":"10.60692/0z7cv-r1b19","title":"Melatonin Act as an Antidepressant via Attenuation of Neuroinflammation by Targeting Sirt1/Nrf2/HO-1 Signaling","year":2020,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Neuroinflammation; Melatonin; Luzindole; Oxidative stress; Antidepressant; Inflammation; Lipopolysaccharide; Sickness behavior","score_opus":0.03213436351021659,"score_gpt":0.2226691080200975,"score_spread":0.19053474450988092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6976416929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762493,0.0000027541994,0.021597624,0.00014446393,0.00014016562,0.00043656005,0.000054516415,0.00026799063,0.0011066268],"genre_scores_gemma":[0.9993176,2.661917e-7,0.00012663301,0.00041137612,0.000055511915,0.000015733944,0.000046695517,0.000017454107,0.000008759654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979606,0.00020550344,0.00082421006,0.00025803817,0.0005099941,0.00024161658],"domain_scores_gemma":[0.99884254,0.000030269928,0.0006696914,0.00021525747,0.000103638326,0.0001385783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027449493,0.00019698724,0.0002406201,0.00013463096,0.0001646628,0.0001619155,0.00025465316,0.000094662784,0.000039280763],"category_scores_gemma":[0.00025754323,0.0001804996,0.00007551191,0.00036263373,0.00003951031,0.001887211,0.000051827945,0.00012523726,0.00036453689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044267904,0.000018109718,0.040133897,0.0013937523,0.000033851273,0.000011803402,0.2221207,0.008623964,0.72263175,0.00091714074,0.00045883897,0.0032134948],"study_design_scores_gemma":[0.0009771783,0.00012738294,0.0033302542,0.00007365807,0.000012938222,0.000013097169,0.0055297483,0.07146376,0.9180755,0.0000048094025,0.00012875702,0.00026290558],"about_ca_topic_score_codex":0.000008812149,"about_ca_topic_score_gemma":4.0524146e-8,"teacher_disagreement_score":0.21659096,"about_ca_system_score_codex":0.000029784598,"about_ca_system_score_gemma":0.000030403271,"threshold_uncertainty_score":0.736056},"labels":[],"label_agreement":null},{"id":"W6977219175","doi":"10.60692/5e4he-pxf39","title":"Reliable biomarkers for decreased spatial navigation in the Young People with Obesity: Increased serum CRP and QUIN levels","year":2022,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Kynurenine; Quinolinic acid; Kynurenic acid; Obesity; Kynurenine pathway; Montreal Cognitive Assessment; Cognitive flexibility; Cognition","score_opus":0.02427669244259122,"score_gpt":0.21160369614849509,"score_spread":0.18732700370590386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6977219175","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940251,0.000001561029,0.0035474969,0.0001312697,0.00014550175,0.0011842117,0.0002946347,0.000082948536,0.0005872941],"genre_scores_gemma":[0.9990086,5.6470352e-8,0.000080063284,0.00039700908,0.000019092347,0.000427019,0.000035839374,0.000009892431,0.00002242384],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986685,0.00018875735,0.00033102834,0.00018987064,0.00038635885,0.00023550633],"domain_scores_gemma":[0.999423,0.000051804145,0.00020975314,0.000224287,0.00004078718,0.000050334038],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059459603,0.00014118494,0.0001501196,0.0001500662,0.00047028225,0.00019357745,0.0002051856,0.00003846258,0.000014676229],"category_scores_gemma":[0.000051056537,0.000102360085,0.000034429897,0.0004589294,0.00003615347,0.00052144454,0.000054347172,0.00009331582,0.000012709645],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011805823,0.000030058252,0.81442726,0.00076206063,0.000024650491,0.000012854988,0.18131831,0.00044633393,0.00038090933,0.00061392336,0.000269489,0.00053354463],"study_design_scores_gemma":[0.006780501,0.00035217218,0.8678538,0.00013345783,0.000028654455,0.00034635453,0.09276733,0.024752695,0.0061022183,0.000021564492,0.00039817556,0.0004630885],"about_ca_topic_score_codex":0.00027380616,"about_ca_topic_score_gemma":0.00001961976,"teacher_disagreement_score":0.088550985,"about_ca_system_score_codex":0.00009141173,"about_ca_system_score_gemma":0.000063421394,"threshold_uncertainty_score":0.41741234},"labels":[],"label_agreement":null},{"id":"W6978031074","doi":"10.6084/m9.figshare.26586243.v1","title":"Additional file 1 of First trimester human umbilical cord perivascular cells (HUCPVC) modulate the kynurenine pathway and glutamate neurotransmission in an LPS-induced mouse model of neuroinflammation","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; CReATe Fertility Centre","funders":"","keywords":"Neuroinflammation; Kynurenine pathway; Umbilical cord; Glutamate receptor; Neurotransmission; Microglia; Kynurenine; First trimester","score_opus":0.05217385529038486,"score_gpt":0.25707918228844984,"score_spread":0.20490532699806496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6978031074","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43164945,0.000009367032,8.407528e-7,0.000052598993,0.000009973802,0.0002556912,0.5678834,0.00004265439,0.00009606464],"genre_scores_gemma":[0.933253,0.0000026331704,0.000029999728,0.000061032588,0.000025715863,0.0001851048,0.066155344,0.000033337557,0.00025384602],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987701,0.00010954352,0.00029460306,0.00038786823,0.00026652595,0.00017134433],"domain_scores_gemma":[0.99901944,0.0005297323,0.00007946775,0.00027203106,0.00003324734,0.00006610586],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000033417473,0.00015665867,0.00016671896,0.000103415055,0.00008665393,0.00006056892,0.00023015407,0.00008118741,0.32282546],"category_scores_gemma":[0.00046936685,0.00012100207,0.00009439689,0.00022309531,0.000035350404,0.00026901436,0.000070682814,0.00019419946,0.00004275853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003777893,0.000088009096,3.72227e-7,0.000321796,0.000002369,0.000011745624,0.00029741545,0.0014095288,0.88024306,0.000014818564,0.11572625,0.0018468349],"study_design_scores_gemma":[0.00044431488,0.0002926571,0.0011864639,0.0012045616,0.0000043918167,0.000008337808,0.000018884384,0.35316586,0.6313554,0.00018013005,0.011919047,0.00021994482],"about_ca_topic_score_codex":0.000003137476,"about_ca_topic_score_gemma":0.000013801733,"teacher_disagreement_score":0.50172806,"about_ca_system_score_codex":0.000009476933,"about_ca_system_score_gemma":0.00005551329,"threshold_uncertainty_score":0.67779356},"labels":[],"label_agreement":null},{"id":"W6979954090","doi":"","title":"Anti-inflammatory role of IDO and tryptophan metabolites","year":2016,"lang":"en","type":"other","venue":"cIRcle (University of British Columbia)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Kynurenine; Inflammation; Kynurenic acid; Cytokine; Immune system; Kynurenine pathway; Chemokine","score_opus":0.005894057717861284,"score_gpt":0.17685278729678783,"score_spread":0.17095872957892655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6979954090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7509543,0.0028365462,0.000029514484,0.00003318417,0.00019082494,0.0004038069,0.0010283102,0.00018728172,0.24433626],"genre_scores_gemma":[0.8348895,0.002885844,0.00013020652,0.000044602228,0.00006514235,4.94215e-7,0.000005951543,0.00014411366,0.16183417],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99876606,0.000081939244,0.00012774584,0.0005139123,0.000264046,0.0002463201],"domain_scores_gemma":[0.9991708,0.000066859735,0.0002992342,0.00031533017,0.000034854325,0.000112966714],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006479422,0.00008374853,0.00048628967,0.0001303664,0.00008155861,0.00003853318,0.00042332517,0.00022878757,0.0015379197],"category_scores_gemma":[0.000053662734,0.00024717973,0.00013899169,0.00015526504,0.00080449594,0.00013980884,0.00017312964,0.00010539467,0.000053173524],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017566426,0.0002255685,0.0041978126,0.0006247462,0.000097263895,0.00016644046,0.00021756373,1.1774336e-7,0.18891193,0.00012445713,0.09760558,0.70781094],"study_design_scores_gemma":[0.0027239597,0.00007907144,0.82335657,0.0009723082,0.00008291064,0.000062184234,0.00093577703,0.000007710705,0.0012476903,0.0013484772,0.16843902,0.0007443389],"about_ca_topic_score_codex":0.010465213,"about_ca_topic_score_gemma":0.025482062,"teacher_disagreement_score":0.81915873,"about_ca_system_score_codex":0.000012665506,"about_ca_system_score_gemma":0.000066037275,"threshold_uncertainty_score":0.99999803},"labels":[],"label_agreement":null},{"id":"W6982556916","doi":"","title":"The Interaction Between Family Functioning and the PCDH9 rs9540720 Polymorphism on Major Depressive Disorder in Chinese Freshmen","year":2025,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Public health; China; The Republic; Medical school; Mental health; Cohort; Disease","score_opus":0.10747370507137557,"score_gpt":0.4792260228132938,"score_spread":0.3717523177419182,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6982556916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9777381,0.008214938,0.00018829745,0.0022506306,0.0008073317,0.00070392725,0.000017257593,0.000031150415,0.01004838],"genre_scores_gemma":[0.9933031,0.0044176057,0.000006369835,0.001305897,0.00010335775,0.00008932525,0.000002347206,0.000026491041,0.0007455005],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99734867,0.00068293087,0.00064232474,0.00050027116,0.000468906,0.0003569172],"domain_scores_gemma":[0.9956362,0.0032547489,0.00050348055,0.00045337257,0.00006388288,0.00008829218],"candidate_categories":["scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.00087624486,0.00029462867,0.0004746979,0.0005517216,0.0009268441,0.0015529287,0.0018915406,0.0000871406,0.00034715468],"category_scores_gemma":[0.0016831505,0.0001709855,0.00013524042,0.0012562254,0.00043528154,0.0012899803,0.0008335467,0.00068704993,0.000009051454],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019639884,0.00023890098,0.8174717,0.000047035195,0.00015274234,0.000019401125,0.00069917797,0.00044667296,0.07266751,0.0016906903,0.011285499,0.09331668],"study_design_scores_gemma":[0.0026290875,0.000010412593,0.96489865,0.00026934315,0.000032592736,0.00000382822,0.00042282132,0.00025917272,0.0099899275,0.016821317,0.0044328673,0.00022997516],"about_ca_topic_score_codex":0.0012758503,"about_ca_topic_score_gemma":0.000254337,"teacher_disagreement_score":0.14742695,"about_ca_system_score_codex":0.00006380528,"about_ca_system_score_gemma":0.00007398708,"threshold_uncertainty_score":0.9994835},"labels":[],"label_agreement":null},{"id":"W6989275356","doi":"","title":"Antipsychotics Prevent Psychosine Induced Toxicity in Glial Cells.","year":2023,"lang":"en","type":"dissertation","venue":"Trinity's Access to Research Output (TARA) (Trinity College Dublin)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health Service Executive; Wellcome Trust; Canadian Institute for Theoretical Astrophysics","keywords":"Haloperidol; Astrocyte; Myelin; Dopamine; Toxicity; Neuroprotection; Oligodendrocyte; Neuroglia","score_opus":0.22455206317617274,"score_gpt":0.45006928344787517,"score_spread":0.22551722027170243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6989275356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9712076,0.0000690749,0.000011644194,0.0023504114,0.0050193975,0.0072009345,0.0013601292,0.0005470959,0.012233715],"genre_scores_gemma":[0.96757525,0.00095026335,0.00007392173,0.0007610326,0.00080791843,0.00090678537,0.00055591,0.00034389322,0.028025003],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9836431,0.0026207326,0.0021930465,0.003438637,0.004898674,0.0032057827],"domain_scores_gemma":[0.991288,0.0034243485,0.0006133812,0.0022874924,0.0010631079,0.0013236796],"candidate_categories":["metaresearch","metaepi_narrow","scholarly_communication","open_science","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.004502428,0.0013615724,0.0018285797,0.006790284,0.0010965647,0.0016996849,0.006268627,0.0015207584,0.00069052237],"category_scores_gemma":[0.008819144,0.001447874,0.00059309293,0.015197985,0.00032509718,0.0012837842,0.0012696882,0.0058922092,0.0021994705],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.063413836,0.036093112,0.0018380163,0.007771378,0.0005578589,0.006194129,0.011040862,0.00091460545,0.28085414,0.017640142,0.51165473,0.062027197],"study_design_scores_gemma":[0.016689336,0.0034112476,0.1160587,0.0020999697,0.0000861835,0.000022431246,0.004129476,0.0011813928,0.78462374,0.0069113574,0.059508707,0.0052774823],"about_ca_topic_score_codex":0.0014316352,"about_ca_topic_score_gemma":0.01772204,"teacher_disagreement_score":0.5037696,"about_ca_system_score_codex":0.0008668969,"about_ca_system_score_gemma":0.0021636088,"threshold_uncertainty_score":0.9999135},"labels":[],"label_agreement":null},{"id":"W6989640970","doi":"","title":"Brain lipids and cholesterol in neuropsychiatric disorders","year":2013,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Mechanism (biology); Cholesterol; Neurotransmission; Animal studies; Prefrontal cortex; Neuroplasticity","score_opus":0.012138623062894495,"score_gpt":0.235691379588313,"score_spread":0.2235527565254185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6989640970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94451904,0.0002514425,6.3259186e-8,0.00019138638,0.0018437789,0.0012823067,0.00025969415,0.00030088762,0.051351383],"genre_scores_gemma":[0.98472726,0.001016481,0.000068138856,0.0027372444,0.00006132473,0.00025276284,0.00013326254,0.00030098995,0.010702526],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9942141,0.00074708124,0.0009914475,0.0021055243,0.00081661495,0.0011252206],"domain_scores_gemma":[0.99750704,0.00062509294,0.0005061417,0.00086251664,0.00006821103,0.00043099595],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004168977,0.0010491544,0.00081180944,0.001102858,0.0007415196,0.0002545277,0.0010259944,0.0008257929,0.00026753035],"category_scores_gemma":[0.0019326735,0.0011140108,0.00028431162,0.0014725813,0.00016254086,0.001099598,0.0001936929,0.002094195,0.00055313116],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000388811,0.0010162898,0.00055277353,0.0009928363,0.000046388952,0.00006709558,0.00007108527,0.00003957259,0.35532698,0.049087565,0.00015277519,0.59225786],"study_design_scores_gemma":[0.018493628,0.0019883406,0.2495909,0.0017521819,0.0002540355,0.0001970126,0.002009686,0.00040970952,0.21449433,0.13953537,0.3603848,0.010890005],"about_ca_topic_score_codex":0.0003734721,"about_ca_topic_score_gemma":0.0030554668,"teacher_disagreement_score":0.58136785,"about_ca_system_score_codex":0.00018213135,"about_ca_system_score_gemma":0.000051633702,"threshold_uncertainty_score":0.999131},"labels":[],"label_agreement":null},{"id":"W6991066085","doi":"","title":"Examining the influence of inflammatory signaling on drug-induced behaviours","year":2018,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Disease; Inflammation; Immune system; Signal transduction","score_opus":0.032374861027711616,"score_gpt":0.2599548387265797,"score_spread":0.2275799776988681,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6991066085","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9746884,0.000032896947,1.260909e-8,0.0000100190755,0.0010543459,0.00081414444,0.00029107713,0.00023748279,0.022871593],"genre_scores_gemma":[0.9969875,0.000037026883,0.000044171506,0.00061699573,0.00006306103,0.000112556656,0.00006920533,0.00020296457,0.0018664673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9945871,0.0007006882,0.0010818745,0.0013947483,0.0014052101,0.0008303662],"domain_scores_gemma":[0.99598795,0.0010625387,0.0011796057,0.0012130815,0.00031355963,0.00024326236],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0010233741,0.00084281684,0.000678784,0.00048977986,0.0014053722,0.0001084464,0.0017489004,0.0006119157,0.00014075488],"category_scores_gemma":[0.002991961,0.0007275872,0.00032174416,0.00083817064,0.00026433653,0.0006292787,0.00017208942,0.0018161231,0.0002729226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019495809,0.00015296611,0.00005615149,0.00014545649,0.000031286054,0.00004297022,0.00008751302,0.00014321851,0.96641254,0.012131371,0.0000053001154,0.02059627],"study_design_scores_gemma":[0.0006416453,0.0002564541,0.009283578,0.0008391888,0.000075068114,0.000009699822,0.0007721082,0.0000051045517,0.98267573,0.0027439075,0.0018675738,0.0008299544],"about_ca_topic_score_codex":0.00012261215,"about_ca_topic_score_gemma":0.0003793688,"teacher_disagreement_score":0.022299124,"about_ca_system_score_codex":0.0002384865,"about_ca_system_score_gemma":0.00011129347,"threshold_uncertainty_score":0.9998947},"labels":[],"label_agreement":null},{"id":"W6996232030","doi":"","title":"Retracer la première écriture de Madeleine Ferron","year":2012,"lang":"fr","type":"other","venue":"uO Research (University of Ottawa)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Ottawa","keywords":"Feature (linguistics); Exoticism; Identity (music)","score_opus":0.04525513474801889,"score_gpt":0.29849088895358833,"score_spread":0.25323575420556943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6996232030","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020738639,0.00077906344,0.00027069036,0.005916365,0.00029047797,0.00069273735,0.0001978358,0.00008612989,0.9710281],"genre_scores_gemma":[0.11739028,0.0011019374,0.001121169,0.000063723055,0.00025374367,8.105391e-7,0.00001806743,0.00013247601,0.8799178],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948218,0.0015384977,0.00016847256,0.0007884341,0.0012721451,0.0014106727],"domain_scores_gemma":[0.9975311,0.00075471867,0.00017370305,0.0007804311,0.00018974753,0.0005702602],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0013808524,0.0003584556,0.00047662132,0.0008452967,0.0005033475,0.00006252835,0.0017435893,0.0010663883,0.045971848],"category_scores_gemma":[0.0006992076,0.00043647375,0.00026834023,0.0010921665,0.0023400176,0.00034640488,0.00063432293,0.0021411567,0.002249956],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011568806,0.0018754784,0.020495754,0.0024430407,0.00019362268,0.0013418775,0.005284907,0.00002198221,0.12419251,0.34056172,0.4544494,0.049024057],"study_design_scores_gemma":[0.00096703944,0.00020650138,0.020187343,0.0003075216,0.00003111948,0.000041952924,0.0021261347,0.00023139716,0.0021609277,0.00033080418,0.97302175,0.00038750735],"about_ca_topic_score_codex":0.00025263685,"about_ca_topic_score_gemma":0.0010441476,"teacher_disagreement_score":0.5185724,"about_ca_system_score_codex":0.0003336249,"about_ca_system_score_gemma":0.00042078,"threshold_uncertainty_score":0.9998087},"labels":[],"label_agreement":null},{"id":"W6996421485","doi":"","title":"2019 Second Quarter Technical Report - Potato value chain development in Cameroon","year":2021,"lang":"en","type":"other","venue":"MELSpace (ICARDA (The International Center for Agricultural Research in Dry Areas))","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Quarter (Canadian coin); Value (mathematics); Technical report; Chain (unit); Technical progress","score_opus":0.050616920905944204,"score_gpt":0.3369823424301903,"score_spread":0.2863654215242461,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6996421485","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1518183,0.0020282757,0.00014620839,0.07405221,0.0063016927,0.010688582,0.0015190535,0.00045895413,0.7529867],"genre_scores_gemma":[0.19982544,0.0002778257,0.0005726355,0.00076181575,0.0009302238,0.0014789117,0.00176711,0.00027264873,0.7941134],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99480575,0.00048893626,0.0006508991,0.001216928,0.0018944931,0.0009429686],"domain_scores_gemma":[0.99818987,0.00069037045,0.00023366803,0.00051091623,0.00020091301,0.0001742399],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012697029,0.0004422762,0.0004722105,0.000624444,0.00013653956,0.0002488873,0.0015565071,0.00032811178,0.0013307002],"category_scores_gemma":[0.0011082689,0.00028550948,0.0002559022,0.0007469932,0.00024821557,0.0001319589,0.00060981774,0.0012084822,0.00012047051],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025469484,0.00096227974,0.0020437755,0.00020733806,0.00012105692,0.0011649712,0.00076938083,0.000027882008,0.02987628,0.0032772012,0.957627,0.0036681695],"study_design_scores_gemma":[0.0013961387,0.00005840541,0.0147936465,0.0008979948,0.0000031813681,0.00020318569,0.0007262531,0.000036872363,0.007938796,0.0003070165,0.9731428,0.00049567956],"about_ca_topic_score_codex":0.00039457448,"about_ca_topic_score_gemma":0.007825266,"teacher_disagreement_score":0.07329039,"about_ca_system_score_codex":0.0008022653,"about_ca_system_score_gemma":0.00024368666,"threshold_uncertainty_score":0.9999597},"labels":[],"label_agreement":null},{"id":"W6997103863","doi":"","title":"The use of a filter product to remove phosphorus from surface runoff in agricultural fields","year":2021,"lang":"en","type":"dissertation","venue":"UWSpace (University of Waterloo)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Ministry of Agriculture, Food and Rural Affairs; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Filter (signal processing); Phosphorus; Surface runoff; Suspended solids; Geotextile; Clogging; Raw material","score_opus":0.02241265596738404,"score_gpt":0.20734434289783055,"score_spread":0.1849316869304465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6997103863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969372,0.0001764334,0.0000010573395,0.0018165571,0.00039760047,0.00034753376,0.00009176382,0.000019520934,0.00021231054],"genre_scores_gemma":[0.5795067,0.0003574234,0.00073177257,0.00009983625,0.000022839766,5.0381175e-7,0.00015776993,0.000018723305,0.41910446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866474,0.00012268008,0.00014932845,0.00050197635,0.00030524583,0.00025603783],"domain_scores_gemma":[0.9990221,0.00022313574,0.00018296951,0.0004051287,0.00010464551,0.000062005056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000056542365,0.00020032772,0.00031662625,0.0000736621,0.00013235182,0.00004396993,0.0004921686,0.00016419895,0.00010404541],"category_scores_gemma":[0.00020213771,0.00016642682,0.00014827418,0.00041761363,0.00007893609,0.00019683663,0.00010801186,0.00026373786,0.0000204527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010820911,0.00028314439,0.0009332004,0.00015820797,0.00007276736,0.00014808927,0.2369005,0.0009816869,0.7306432,0.00017396321,0.021777542,0.006845596],"study_design_scores_gemma":[0.0009773422,0.0001520549,0.1288292,0.00048893574,0.00005315789,0.0000023436335,0.1912874,0.00010048431,0.671079,0.00011174723,0.0062912493,0.0006271246],"about_ca_topic_score_codex":0.054067492,"about_ca_topic_score_gemma":0.12507498,"teacher_disagreement_score":0.41889215,"about_ca_system_score_codex":0.000039985196,"about_ca_system_score_gemma":0.000066695146,"threshold_uncertainty_score":0.9522315},"labels":[],"label_agreement":null},{"id":"W6997158713","doi":"","title":"Tumor necrosis factor-alpha regulates the function of antidepressants and impact of mutant Huntingtin protein","year":2016,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Brain Research Centre; Strong","keywords":"Huntingtin; Mutant; Function (biology); Mutation; Tumor necrosis factor alpha; Process (computing); Tumor cells","score_opus":0.017974304831951612,"score_gpt":0.2519127677209747,"score_spread":0.2339384628890231,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6997158713","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908712,0.00015081251,1.0516723e-7,0.00000915014,0.0003554128,0.0011789881,0.0016840532,0.00010704877,0.0056432434],"genre_scores_gemma":[0.99781823,0.00010247577,0.000024042525,0.000046565565,0.000022215878,0.00006854351,0.000039627896,0.00013180017,0.0017464993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99610454,0.0004363107,0.0009820821,0.0010352221,0.0008182738,0.0006235674],"domain_scores_gemma":[0.9968177,0.00050449674,0.0014630425,0.0007922587,0.0002535638,0.00016895655],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047913878,0.00068234146,0.0008076718,0.0003504747,0.0006845136,0.0000760111,0.00070407515,0.0003900122,0.00026644964],"category_scores_gemma":[0.0023894222,0.0004524208,0.00048352432,0.0006037605,0.00029710538,0.0006553916,0.00014809505,0.0006735947,0.000024274208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053684326,0.00013883291,0.00019749263,0.000310853,0.00007391682,0.0000062861886,0.000019514504,0.0000019945833,0.94363195,0.0030887583,0.0000013615855,0.051992226],"study_design_scores_gemma":[0.0009277824,0.0003516552,0.05586866,0.0007536787,0.00006383803,0.000010361325,0.000094033705,0.0000067620854,0.9338452,0.007255577,0.00033679506,0.00048563816],"about_ca_topic_score_codex":0.00042318198,"about_ca_topic_score_gemma":0.00014230679,"teacher_disagreement_score":0.055671167,"about_ca_system_score_codex":0.00016144138,"about_ca_system_score_gemma":0.000106691004,"threshold_uncertainty_score":0.99979275},"labels":[],"label_agreement":null},{"id":"W7014948116","doi":"","title":"A role for astroycte-related genes in suicide","year":2009,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McGill University","keywords":"Gene; Astrocyte; Epigenetics; Gene expression; Transcription factor; Nervous system; Transcription (linguistics); Regulation of gene expression","score_opus":0.019224824519619262,"score_gpt":0.2601542816396292,"score_spread":0.24092945712000996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7014948116","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93676186,0.00059023825,1.357986e-7,0.000031221465,0.00082576944,0.0015873555,0.0008486686,0.00037237364,0.058982376],"genre_scores_gemma":[0.9851582,0.00028231085,0.00035643968,0.00071285304,0.000039649985,0.00033964962,0.0006621325,0.00024398595,0.012204763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9948984,0.00036265684,0.0011057575,0.0017163224,0.0007162501,0.0012006243],"domain_scores_gemma":[0.9977574,0.0005130121,0.0005662411,0.00071506365,0.00014904008,0.0002992779],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00052193296,0.0008975849,0.0008678754,0.0007785129,0.00074197684,0.00012583769,0.0010600216,0.0010157882,0.0001813548],"category_scores_gemma":[0.002033511,0.0009816667,0.0005268889,0.0010638946,0.00007485229,0.0006407747,0.000072027484,0.0013668732,0.00029123228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043022825,0.00035013608,0.00001675915,0.00013649685,0.00002614036,0.000051478313,0.000012332737,0.00010288442,0.6589631,0.036068004,0.0000073955553,0.30383503],"study_design_scores_gemma":[0.0032459446,0.0004033563,0.0055661043,0.00047222234,0.00007193849,0.000027726663,0.00036832926,0.00012809981,0.8718149,0.07888047,0.037415173,0.001605718],"about_ca_topic_score_codex":0.00019641177,"about_ca_topic_score_gemma":0.0037980748,"teacher_disagreement_score":0.30222932,"about_ca_system_score_codex":0.000392529,"about_ca_system_score_gemma":0.00008741233,"threshold_uncertainty_score":0.9992634},"labels":[],"label_agreement":null},{"id":"W7015824480","doi":"","title":"Treatment of the placenta prevents adverse effects of gestational hypoxia on fetal brain development","year":2017,"lang":"en","type":"article","venue":"Oxford University Research Archive (ORA) (University of Oxford)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Rita and Alex Hillman Foundation; Stollery Children’s Hospital Foundation; Children's Hospital Foundation; Engineering and Physical Sciences Research Council; Canadian Institutes of Health Research; Royal Alexandra Hospital Foundation; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Fetus; Placenta; Hypoxia (environmental); Offspring; Oxidative stress; Pregnancy; Trophoblast; Gestation","score_opus":0.03430522196534787,"score_gpt":0.27202820057164784,"score_spread":0.23772297860629998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7015824480","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98001885,0.0000061040614,0.00036171757,0.000709174,0.00008545912,0.00081864884,0.00019798221,0.000016505748,0.017785527],"genre_scores_gemma":[0.99198836,0.00024293929,0.0011934694,0.000013779715,0.0000093269955,3.5651163e-7,0.000014771182,0.000012265591,0.006524707],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99739045,0.00052157085,0.00014737174,0.0004737359,0.0010082998,0.00045857803],"domain_scores_gemma":[0.9975548,0.0010371186,0.00036320504,0.00073802745,0.0001242934,0.0001826029],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00022252771,0.0001986552,0.00031633282,0.0004160892,0.0014152057,0.000013523476,0.0017620466,0.00008443042,0.0000805387],"category_scores_gemma":[0.00040548271,0.00019356949,0.00026047122,0.00031104093,0.0017995008,0.00035611194,0.0008517245,0.00025510538,0.0000069539688],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019772958,0.013036272,0.1448586,0.0019693456,0.0011340876,0.0013357528,0.041766454,0.000679628,0.51120055,0.086086854,0.006251414,0.1719081],"study_design_scores_gemma":[0.010653233,0.0023231464,0.77744114,0.00036843892,0.000051068157,0.000008344658,0.0059025823,0.0006422521,0.118113995,0.0014857358,0.08258451,0.000425526],"about_ca_topic_score_codex":0.0002983298,"about_ca_topic_score_gemma":0.0004731635,"teacher_disagreement_score":0.63258255,"about_ca_system_score_codex":0.00025192118,"about_ca_system_score_gemma":0.00053094124,"threshold_uncertainty_score":0.99988484},"labels":[],"label_agreement":null},{"id":"W7018162844","doi":"","title":"Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression","year":2020,"lang":"en","type":"article","venue":"Arrow@dit (Dublin Institute of Technology)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cilag; National Institute of Mental Health; National Health and Medical Research Council; Stanley Center for Psychiatric Research, Broad Institute; University of North Carolina at Chapel Hill; School of Medicine, Emory University; National Institutes of Health; Centre for Cognitive Ageing and Cognitive Epidemiology; H. Lundbeck A/S; Medical Research Council; Siemens Healthineers; Innovative Medicines Initiative; Chinese Society of Clinical Oncology; Rheinische Friedrich-Wilhelms-Universität Bonn; Universitair Medisch Centrum Groningen; Dokuz Eylül Üniversitesi; Vetenskapsrådet; GGZ Drenthe; Pfizer; Rivierduinen; GGZ inGeest; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Bundesministerium für Bildung und Forschung; Erasmus Medisch Centrum; Vrije Universiteit Amsterdam; Karolinska Institutet; ZonMw; King's College London; Max-Planck-Gesellschaft; Rijksuniversiteit Groningen; Universiteit Leiden; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Cancer Institute; University College London; Lundbeckfonden; Kaiser Permanente; Cardiff University; Universität Greifswald; GGZ Friesland; Philipps-Universität Marburg; Aarhus Universitet; Universität Basel; QIMR Berghofer Medical Research Institute; Højteknologifonden; Leids Universitair Medisch Centrum; Department of Health and Social Care; National Institute for Health and Care Research; Aarhus Universitetshospital; University of Southern California; Foundation for the National Institutes of Health; Broad Institute; Wellcome Trust; Westfälische Wilhelms-Universität Münster; Emory University; National Science Foundation; Massachusetts General Hospital; Dalhousie University; GlaxoSmithKline; AstraZeneca; University of Worcester","keywords":"Human leukocyte antigen; Haplotype; Major histocompatibility complex; Depression (economics); Allele; Genetic association; Etiology; Genetic predisposition","score_opus":0.04124801526538607,"score_gpt":0.2505584281666833,"score_spread":0.2093104129012972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7018162844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98963517,0.00013390425,0.00020689463,0.00829439,0.00010751106,0.00032178088,0.00003159443,0.0006734424,0.0005953326],"genre_scores_gemma":[0.9983663,0.00008604368,0.00053518993,0.00083291845,0.00004094544,0.000021590924,0.000010161577,0.00003496949,0.00007189249],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980658,0.000046165627,0.00036599574,0.00076996785,0.00035471522,0.00039732893],"domain_scores_gemma":[0.9990163,0.00007174489,0.00033975902,0.0003564923,0.00007356322,0.00014212736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009542503,0.00028942566,0.00045447444,0.00028305774,0.00030716378,0.000050955565,0.00064898015,0.0003705088,0.000021480148],"category_scores_gemma":[0.0013367679,0.00023978739,0.00006755597,0.00087675574,0.0014255045,0.0003724784,0.00025148506,0.00047323253,0.000019604817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001749318,0.00027587352,0.0153403785,0.000049447062,0.00004742434,0.00016492442,0.00012698823,0.000059316648,0.9650304,0.014360781,0.0019720546,0.0023974816],"study_design_scores_gemma":[0.0021053122,0.00047731234,0.022562958,0.00018231271,0.000027778671,0.00001525951,0.00022639762,0.00048697935,0.95796764,0.00094621413,0.014551285,0.00045056682],"about_ca_topic_score_codex":0.0000118836415,"about_ca_topic_score_gemma":0.00014815472,"teacher_disagreement_score":0.013414566,"about_ca_system_score_codex":0.00002667856,"about_ca_system_score_gemma":0.00007788267,"threshold_uncertainty_score":0.9778246},"labels":[],"label_agreement":null},{"id":"W7018358976","doi":"","title":"Development of animal models to study effects of maternal infection during pregnancy on offspring behavior","year":2011,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Neurosciences, Mental Health and Addiction; AstraZeneca Canada; Canadian Institutes of Health Research; Canadian Psychiatric Research Foundation; National Alliance for Research on Schizophrenia and Depression; AstraZeneca","keywords":"Offspring; Prepulse inhibition; Pregnancy; Immune system; Gestation; Dopamine; Fetus","score_opus":0.03717331176646778,"score_gpt":0.26559706946529293,"score_spread":0.22842375769882517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7018358976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99198335,0.00002424411,3.7863413e-7,2.3803973e-7,0.0007197394,0.0021663636,0.00006629908,0.00014223867,0.004897138],"genre_scores_gemma":[0.99841267,0.000027079392,0.00040088396,0.000012037059,0.000009376604,0.0004893448,0.000013217238,0.00014355517,0.0004918528],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961536,0.00025016448,0.0010224979,0.0010806032,0.00095747533,0.0005356632],"domain_scores_gemma":[0.9982588,0.000103503065,0.0007168242,0.0005558922,0.00015737116,0.00020760037],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019086745,0.00063439267,0.00069500826,0.0007017579,0.00052348326,0.000030504792,0.00058305217,0.00032259704,0.000048176353],"category_scores_gemma":[0.00029134724,0.00067127415,0.00021574054,0.0005181259,0.00003099879,0.00047829855,0.00018863016,0.000644306,0.000053023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006445879,0.0017766148,0.00040940047,0.0010377169,0.00005571905,0.0000769077,0.00024005522,0.000026447391,0.9302347,0.0026150807,2.4268102e-8,0.062882766],"study_design_scores_gemma":[0.0010422054,0.0006910666,0.15228756,0.0015495074,0.000074892494,0.000005887709,0.000099634184,0.0000024883295,0.8434532,0.0002932824,0.000012124462,0.00048815226],"about_ca_topic_score_codex":0.00017352853,"about_ca_topic_score_gemma":0.00042509544,"teacher_disagreement_score":0.15187815,"about_ca_system_score_codex":0.00022757752,"about_ca_system_score_gemma":0.000045282675,"threshold_uncertainty_score":0.9995738},"labels":[],"label_agreement":null},{"id":"W7029167272","doi":"","title":"Identifying Baseline Predictors of Relapse and Stratifying Immune Composition in Major Depressive Disorder","year":2023,"lang":"en","type":"dissertation","venue":"MacSphere (McMaster University)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Major depressive disorder; Depression (economics); Antidepressant; Immune system; Rating scale; Longitudinal study; Cytokine; Psychoneuroimmunology; Hamilton Rating Scale for Depression","score_opus":0.01697765623246081,"score_gpt":0.23562499768588654,"score_spread":0.21864734145342574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7029167272","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96424997,0.0003292095,0.00016263034,0.00003319312,0.00051706954,0.0005299575,0.00006435257,0.00011973277,0.03399387],"genre_scores_gemma":[0.8802888,0.0003575129,0.00008697052,0.000021808071,0.000029214465,0.0000033415297,0.00024662708,0.00006435259,0.11890138],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99822426,0.00022623834,0.00035926705,0.0006125063,0.0002898644,0.00028787612],"domain_scores_gemma":[0.9991079,0.00023094047,0.00033453343,0.00021162251,0.00004217835,0.000072844436],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009589243,0.00029674405,0.00037891982,0.00048332923,0.00015734967,0.000055570395,0.00032649643,0.00025513454,0.002794007],"category_scores_gemma":[0.00008349189,0.00034665686,0.00010781146,0.0008951243,0.00010322301,0.00035333823,0.00011425708,0.00038902485,0.000013009554],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002788824,0.00075898867,0.031035965,0.004088328,0.000221872,0.0011882748,0.01503984,0.00081500015,0.7177482,0.002497424,0.000325627,0.22349162],"study_design_scores_gemma":[0.02682954,0.00070339034,0.420956,0.008677617,0.00083069335,0.00003926848,0.1279418,0.004327639,0.39233145,0.0019795038,0.011063855,0.0043192445],"about_ca_topic_score_codex":0.0002808989,"about_ca_topic_score_gemma":0.002117196,"teacher_disagreement_score":0.38992003,"about_ca_system_score_codex":0.000059455804,"about_ca_system_score_gemma":0.000058623024,"threshold_uncertainty_score":0.99989855},"labels":[],"label_agreement":null},{"id":"W7043144151","doi":"","title":"The relationship between C-reactive protein and depression in older adults: associations with incidence of type 2 diabetes mellitus","year":2015,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; University College London; McGill University","keywords":"Depression (economics); Longitudinal study; Incidence (geometry); Type 2 Diabetes Mellitus; Prospective cohort study; Diabetes mellitus; Mood; Population; Depressive symptoms","score_opus":0.022698112643867188,"score_gpt":0.26630986158972125,"score_spread":0.24361174894585408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7043144151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929321,0.00064581796,4.518543e-8,0.000019513494,0.00016441211,0.0012908821,0.00037324213,0.00006871062,0.0045052837],"genre_scores_gemma":[0.9987702,0.000059822916,0.000074471965,0.000034128236,0.00001760616,0.00017663563,0.00018282536,0.000076627024,0.0006077169],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9966083,0.0006653293,0.00062746106,0.00079146575,0.0008349694,0.0004724542],"domain_scores_gemma":[0.9955116,0.0026518016,0.00080553256,0.0004636001,0.00040151828,0.00016593958],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008014588,0.00042793408,0.0004885167,0.00027645996,0.00078084343,0.000074243064,0.0004924487,0.00048055215,0.0000075098633],"category_scores_gemma":[0.01313042,0.00032090294,0.00007613429,0.0010413758,0.00015502541,0.0006972387,0.00009104553,0.0011999228,0.000019705369],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003060018,0.0013672165,0.53613216,0.0017048016,0.000286505,0.00006672208,0.0012385153,0.00007233474,0.15494782,0.067115344,0.000023766293,0.2339848],"study_design_scores_gemma":[0.001596026,0.00020788409,0.7785784,0.0018862685,0.0000692414,0.0000015572662,0.001152135,0.00001413197,0.18500297,0.03049935,0.00032991974,0.00066212955],"about_ca_topic_score_codex":0.00017312536,"about_ca_topic_score_gemma":0.0016784366,"teacher_disagreement_score":0.24244623,"about_ca_system_score_codex":0.00028727294,"about_ca_system_score_gemma":0.0001160096,"threshold_uncertainty_score":0.9999243},"labels":[],"label_agreement":null},{"id":"W7068027797","doi":"","title":"Nekateri vidiki dobre prakse na Canadian International School, primarni program vzgoje in izobraževanja v Singapurju","year":2009,"lang":"sl","type":"dissertation","venue":"University of Maribor digital library (University of Maribor)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Work (physics); Government (linguistics); Event (particle physics)","score_opus":0.0063034482511714375,"score_gpt":0.18310729913405496,"score_spread":0.17680385088288353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7068027797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83865815,0.0001610406,0.000030381716,0.0025370992,0.00075641106,0.0016622836,0.005499286,0.00029356734,0.15040176],"genre_scores_gemma":[0.9505093,0.00082862255,0.0016890895,0.0003035398,0.00007320615,2.489761e-7,0.008800968,0.00009664577,0.03769835],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99545103,0.0002691909,0.0005838582,0.0015623645,0.0010400222,0.0010935374],"domain_scores_gemma":[0.9966248,0.00024129573,0.0010919283,0.0007933635,0.00026161756,0.0009869428],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017523697,0.0008795118,0.0011212844,0.0023772367,0.00058203744,0.00042155854,0.003440133,0.0010030953,0.0025876071],"category_scores_gemma":[0.00022963843,0.0013181553,0.00068961235,0.0018390854,0.0009958837,0.007282551,0.0007752335,0.0011582145,0.00018332554],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.017620586,0.010761501,0.1861365,0.0031744444,0.0013342766,0.009553057,0.016498428,0.00042614297,0.0026293024,0.009839131,0.05700836,0.6850183],"study_design_scores_gemma":[0.008858552,0.0018643906,0.5199082,0.0017493485,0.00028740324,0.000048525733,0.06172114,0.0012540389,0.001063469,0.0012414479,0.39886978,0.0031337324],"about_ca_topic_score_codex":0.026552768,"about_ca_topic_score_gemma":0.045025025,"teacher_disagreement_score":0.6818845,"about_ca_system_score_codex":0.00057930994,"about_ca_system_score_gemma":0.0031059515,"threshold_uncertainty_score":0.9989268},"labels":[],"label_agreement":null},{"id":"W7114993352","doi":"10.1021/acsomega.5c09713.s001","title":"Higher Plasma Kynurenineto Tryptophan Correlateswith an Increased Incidence of Mild Cognitive Impairment in TreatedMetabolic Syndrome Patients","year":2025,"lang":"","type":"article","venue":"Figshare","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Kynurenine; Metabolic syndrome; Metabolite; Cognition; Kynurenine pathway; Incidence (geometry); Cognitive impairment","score_opus":0.020859194515432253,"score_gpt":0.2650173940976182,"score_spread":0.24415819958218596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7114993352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8658122,0.0006176395,2.544897e-7,0.000030644424,0.00035640565,0.0018732087,0.12953204,0.00008660963,0.0016910397],"genre_scores_gemma":[0.9805527,0.00003690114,0.000012657399,0.0006440933,0.000026226298,0.0003444393,0.017469727,0.00006604634,0.0008472302],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99492663,0.0006374945,0.0011691814,0.0014668523,0.00077758165,0.001022284],"domain_scores_gemma":[0.99716276,0.0008326528,0.00061302434,0.0006775777,0.00033439678,0.00037960272],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011174776,0.00081057695,0.0010073412,0.00095070765,0.00020833491,0.00013181302,0.0010168097,0.00049429305,0.06250297],"category_scores_gemma":[0.0018709532,0.0008168728,0.00025331476,0.0031191045,0.00014203976,0.00075091043,0.00044484416,0.00069126394,0.0007214848],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.031697046,0.091352895,0.53823376,0.017832262,0.0018617458,0.0058401898,0.024286743,0.0025092012,0.014844145,0.0009147322,0.21379597,0.056831323],"study_design_scores_gemma":[0.010825258,0.0016052764,0.94007665,0.01217037,0.00007634516,0.000011769066,0.0002539354,0.0014986783,0.03205306,0.000046202884,0.00057477545,0.00080769253],"about_ca_topic_score_codex":0.00027204302,"about_ca_topic_score_gemma":0.00014060966,"teacher_disagreement_score":0.4018429,"about_ca_system_score_codex":0.00020280972,"about_ca_system_score_gemma":0.00056365354,"threshold_uncertainty_score":0.9994282},"labels":[],"label_agreement":null},{"id":"W7115906310","doi":"10.64898/2025.12.16.693850","title":"Systematic screening of tryptophan metabolism identifies site- and microbial-specific signatures of tryptophan utilization in experimental colitis","year":2025,"lang":"en","type":"article","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Government of Nova Scotia","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft; National Institutes of Health; Else Kröner-Fresenius-Stiftung; Huck Institutes of the Life Sciences; Joachim Herz Stiftung","keywords":"Colitis; Inflammation; Tryptophan; Metabolism; Tryptophan Metabolism; Inflammatory bowel disease; Gut flora","score_opus":0.017250786200455736,"score_gpt":0.2378674109007995,"score_spread":0.22061662470034377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7115906310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915903,0.006521931,0.0006807905,0.00003263859,0.00030516036,0.000725729,0.000054213033,0.00007236589,0.000016830516],"genre_scores_gemma":[0.99907047,0.00020174935,0.00048873044,0.00012182871,0.000024205601,0.000052409374,1.2551324e-7,0.00003150289,0.000008956557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99781513,0.0003393626,0.00071134116,0.0005431947,0.00027592597,0.000315039],"domain_scores_gemma":[0.99881196,0.00024579332,0.00032545745,0.00041823264,0.00010946044,0.00008910736],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033790886,0.00026766036,0.0005991416,0.0005592624,0.00011930819,0.00008633634,0.0002957567,0.00015662929,0.00002462053],"category_scores_gemma":[0.00059151015,0.0002804046,0.00008965495,0.0012383348,0.0002724289,0.00028606332,0.00011244991,0.00016847806,0.000002634436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006799499,0.00015969596,0.0003483244,0.0019705428,0.000018280065,0.000008322072,0.0000931926,0.000011631393,0.9892267,0.008032201,0.00006175377,0.0000013771217],"study_design_scores_gemma":[0.0010475178,0.000026498547,0.037673447,0.0015374421,0.000018310771,2.2529907e-8,0.00010183342,0.0001308888,0.95917803,0.0000063408156,0.000071230104,0.00020845098],"about_ca_topic_score_codex":0.000028250826,"about_ca_topic_score_gemma":0.000004450397,"teacher_disagreement_score":0.03732512,"about_ca_system_score_codex":0.00004211453,"about_ca_system_score_gemma":0.000086424,"threshold_uncertainty_score":0.99996483},"labels":[],"label_agreement":null},{"id":"W7116767324","doi":"10.1016/j.bbih.2025.101166","title":"Neuroinflammation and insulin resistance in major depression and bipolar disorder: Implications for clinical trials evaluating immunometabolic targeted therapies","year":2025,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Life Sciences, University of California, Los Angeles; National Natural Science Foundation of China; Canadian Institutes of Health Research; Global Alliance for Chronic Diseases; AbbVie; Milken Institute","keywords":"Clinical trial; Biomarker; Insulin resistance; Neuroinflammation; Disease; Bipolar disorder; Major depressive disorder; Precision medicine; Depression (economics)","score_opus":0.14804947451109643,"score_gpt":0.46528517161088695,"score_spread":0.3172356970997905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7116767324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9454331,0.04150863,0.0004611477,0.009426252,0.00018340047,0.0027613752,0.00011927679,0.00008577979,0.000021067612],"genre_scores_gemma":[0.9847934,0.010823729,0.0016949292,0.0017080285,0.000027315577,0.000643984,0.000055295222,0.00003213508,0.00022115359],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99369365,0.0038384798,0.0013638618,0.00056296843,0.00014631945,0.00039471107],"domain_scores_gemma":[0.9938047,0.0049826736,0.0005213029,0.0005263895,0.00006128604,0.00010364592],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0064270366,0.00022440973,0.0006206896,0.0003407409,0.0007347088,0.00011989618,0.00028243408,0.00013849542,0.0000063426205],"category_scores_gemma":[0.010572297,0.00021285797,0.0001045247,0.0006578005,0.00024454936,0.0002596162,0.00013800716,0.0004248509,9.4670327e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046496926,0.00051290425,0.06699435,0.00017824187,0.000008513653,3.8356697e-7,0.0016739235,0.0000013586597,0.17526706,0.0027290827,0.0002742597,0.75189495],"study_design_scores_gemma":[0.003826122,0.00013879454,0.9842026,0.00010244796,0.000019736417,0.0000016718047,0.00030480372,0.00010399498,0.0007737156,0.0023749243,0.007971362,0.0001798115],"about_ca_topic_score_codex":0.00029931788,"about_ca_topic_score_gemma":0.0006933649,"teacher_disagreement_score":0.91720825,"about_ca_system_score_codex":0.000057946396,"about_ca_system_score_gemma":0.00038902112,"threshold_uncertainty_score":0.9977621},"labels":[],"label_agreement":null},{"id":"W7117106555","doi":"10.1002/alz70856_097301","title":"Yoga Modulates Alzheimer's Disease Pathophysiology by Targeting Key Biomarkers, Oxidative Stress, Inflammation, and Neurocognition","year":2025,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Disease; Neurocognitive; Biomarker; Oxidative stress; Pathophysiology; Cognition; Intervention (counseling)","score_opus":0.013349552156643024,"score_gpt":0.2457717620693802,"score_spread":0.23242220991273718,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117106555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90645933,0.08652145,0.0006250313,0.0028448736,0.0005892808,0.0011129146,0.0003095162,0.0003138876,0.0012237355],"genre_scores_gemma":[0.99775153,0.0004925262,0.00024602315,0.0011473219,0.000042005948,0.000116396106,0.00017545234,0.000022036613,0.0000066965727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998249,0.00025589846,0.0003254899,0.0006568059,0.00015301295,0.000359816],"domain_scores_gemma":[0.9992406,0.00019484767,0.00015366201,0.00022515772,0.000057566293,0.00012819702],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009224169,0.00025786532,0.00017925465,0.00013148054,0.00035573402,0.00010087612,0.00021794204,0.00007347605,0.00014146761],"category_scores_gemma":[0.00021745036,0.00025821352,0.00006437311,0.00033693036,0.00025559127,0.00040127046,0.00018529176,0.00012430592,0.00003772705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001825685,0.00019436075,0.002285895,0.00001937421,0.0020077094,0.000018235407,0.0002230167,0.000033298296,0.9205525,0.0024745932,0.02091532,0.051093124],"study_design_scores_gemma":[0.00096377765,0.00005618948,0.011525889,0.000039411283,0.0025838874,5.9188386e-7,0.00013407026,0.0014277996,0.96638864,0.010899146,0.005567097,0.00041347806],"about_ca_topic_score_codex":0.000028122113,"about_ca_topic_score_gemma":0.0000049224077,"teacher_disagreement_score":0.091292225,"about_ca_system_score_codex":0.0000026920188,"about_ca_system_score_gemma":0.000041965475,"threshold_uncertainty_score":0.999987},"labels":[],"label_agreement":null},{"id":"W7117238074","doi":"10.1002/alz70857_102001","title":"Cognitive Outcomes in Psychiatric Ward: Preliminary Results","year":2025,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Cognition; Orientation (vector space); Schizophrenia (object-oriented programming); Cognitive impairment; MEDLINE","score_opus":0.028692861808129133,"score_gpt":0.3024414342551739,"score_spread":0.27374857244704476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117238074","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79892254,0.047335565,0.00036746915,0.008000088,0.0031511742,0.0020121785,0.00014090975,0.00043276974,0.13963729],"genre_scores_gemma":[0.9964078,0.00008295968,0.00016842809,0.003092902,0.00001778438,0.00004848204,0.000008195179,0.000013244897,0.00016017392],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99843633,0.00012544227,0.00036122993,0.00052925566,0.00019655726,0.00035119744],"domain_scores_gemma":[0.9992548,0.00034952138,0.00008055679,0.00024754714,0.00002055592,0.000047018322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013732692,0.00018108582,0.0001854327,0.0002978501,0.000113943686,0.000040707004,0.0002969187,0.00007169866,0.000067519126],"category_scores_gemma":[0.0003025961,0.00016891569,0.00008991723,0.0006988604,0.00009368154,0.00015775458,0.00013878904,0.00016958578,0.00019610574],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0074616745,0.006616936,0.23589242,0.00007394539,0.008646873,0.0003596085,0.004046352,0.000096346776,0.01508971,0.01964882,0.10629582,0.5957715],"study_design_scores_gemma":[0.010678538,0.0005093138,0.79604834,0.00009717075,0.0036706198,0.0000059814597,0.0006912844,0.000380039,0.16860728,0.005224378,0.013197675,0.0008893713],"about_ca_topic_score_codex":0.000043951815,"about_ca_topic_score_gemma":0.000040679675,"teacher_disagreement_score":0.59488213,"about_ca_system_score_codex":0.000003668303,"about_ca_system_score_gemma":0.000057763453,"threshold_uncertainty_score":0.6888182},"labels":[],"label_agreement":null},{"id":"W7117292944","doi":"10.1002/phar.70094","title":"C‐Reactive Protein and Neutrophil‐To‐Lymphocyte Ratio: Can They Be Used Interchangeably in Tracking Clozapine‐Related Inflammation?","year":2025,"lang":"en","type":"article","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital; University of Calgary; Provincial Health Services Authority","funders":"","keywords":"Clozapine; Tracking (education); Pattern recognition (psychology); Feature (linguistics); Statistical analysis","score_opus":0.030588620354551253,"score_gpt":0.33410765346439725,"score_spread":0.303519033109846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117292944","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97717595,0.002522754,0.000035317484,0.018674906,0.00036180663,0.0010414956,0.000006027688,0.000031577834,0.00015014027],"genre_scores_gemma":[0.9849914,0.0044574877,0.0000132141495,0.010020722,0.00014219274,0.000045807585,6.241864e-7,0.000029108562,0.00029946776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99728596,0.0012643446,0.0006157633,0.00028117743,0.00020913602,0.000343588],"domain_scores_gemma":[0.998753,0.000547885,0.0003779991,0.0001202839,0.00008240059,0.000118395656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011006673,0.0002915541,0.00038711715,0.0005613107,0.00038261822,0.00007301199,0.00045318072,0.00007676068,0.00015645596],"category_scores_gemma":[0.000033475968,0.00020774972,0.0000804408,0.00040380875,0.0002847399,0.0003407209,0.000054381264,0.0006298848,0.0000012707752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021512462,0.00016039073,0.00020918105,0.0000149688085,0.00010604527,0.000026337744,0.021379825,0.00014780532,0.96103,0.00063824933,0.00039091246,0.01374504],"study_design_scores_gemma":[0.012069429,0.00032122296,0.0011523509,0.00006784236,0.0000330793,0.000052844316,0.0007929395,0.0002724497,0.9749969,0.0041552773,0.005864811,0.00022083324],"about_ca_topic_score_codex":0.00005435686,"about_ca_topic_score_gemma":0.00007499863,"teacher_disagreement_score":0.020586886,"about_ca_system_score_codex":0.0000939658,"about_ca_system_score_gemma":0.000119475444,"threshold_uncertainty_score":0.84717876},"labels":[],"label_agreement":null},{"id":"W7117548335","doi":"10.1016/j.bbi.2025.106245","title":"Epigenetic biomarkers of inflammation in studies on mental health: Current applications, limitations, and future directions","year":2025,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Northern British Columbia","funders":"European Research Council; European Commission","keywords":"Epigenetics; Inflammation; Mental health; Biomarker; Epigenesis; Relation (database)","score_opus":0.05379538915512366,"score_gpt":0.3511861692366208,"score_spread":0.29739078008149716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117548335","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864381,0.00860807,0.000011017332,0.003909521,0.00018870058,0.00066667586,0.000028513745,0.000022755188,0.00012663184],"genre_scores_gemma":[0.9821616,0.017318292,0.000058420577,0.00018173507,0.0000130496,0.00021164655,0.000015399168,0.0000045896295,0.00003527256],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9992276,0.00019529478,0.00024135396,0.00016589477,0.000073338604,0.00009655981],"domain_scores_gemma":[0.9994697,0.00026809945,0.00007808579,0.00013749611,0.00001939516,0.000027220929],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017574221,0.00008627411,0.00012421409,0.00022681984,0.00027047354,0.000015135818,0.000063333064,0.000029042223,0.0000018913372],"category_scores_gemma":[0.00015102822,0.00008343684,0.000020820153,0.00039512393,0.000165421,0.00006495095,0.00004582822,0.00011119563,6.721617e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032983007,0.0003501422,0.0052945563,0.0001188143,0.000006716242,1.4681538e-7,0.0029188555,9.127547e-7,0.04971708,0.0037997705,0.00031295733,0.9374471],"study_design_scores_gemma":[0.001037142,0.00014038838,0.9269759,0.00013731695,0.0000122328665,0.0000021107282,0.0070811245,0.00002385675,0.029515743,0.00079096376,0.03412506,0.00015817684],"about_ca_topic_score_codex":0.000029356652,"about_ca_topic_score_gemma":0.0001139298,"teacher_disagreement_score":0.9372889,"about_ca_system_score_codex":0.000036562484,"about_ca_system_score_gemma":0.00003736651,"threshold_uncertainty_score":0.34024557},"labels":[],"label_agreement":null},{"id":"W7117724307","doi":"10.1093/schizbullopen/sgaf008","title":"An Exploratory Study of Inflammatory Biomarkers and Extrapyramidal Side Effects in Patients with Schizophrenia","year":2025,"lang":"en","type":"article","venue":"Schizophrenia Bulletin Open","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa","funders":"","keywords":"Schizophrenia (object-oriented programming); Exploratory research; Psychosis; Antipsychotic; Extrapyramidal symptoms; Disease","score_opus":0.008748083198740177,"score_gpt":0.24416406991878759,"score_spread":0.2354159867200474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117724307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958614,0.000069376656,0.000009174703,0.00013494122,0.0001527257,0.002621344,0.0000105021745,0.00006977495,0.0010707447],"genre_scores_gemma":[0.99884355,0.0000075418743,0.0005483691,0.0003047852,0.000012866343,0.0001901798,0.000004613009,0.00003956038,0.000048546543],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99715483,0.00065767526,0.0004893698,0.0009101907,0.00039250264,0.00039544457],"domain_scores_gemma":[0.9985727,0.00032740002,0.00019243886,0.0007020903,0.000056802706,0.00014854468],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039230756,0.0003579256,0.00048484383,0.00046091853,0.00019155799,0.00020230966,0.0010361444,0.00010892199,0.00004385341],"category_scores_gemma":[0.00028677232,0.00031243358,0.000034241042,0.0007211874,0.00032711957,0.0003489479,0.00048282044,0.00028930313,0.000018878123],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.08833211,0.0151447095,0.70951515,0.00084000017,0.00032981887,0.00029356268,0.007517479,0.00024601308,0.055779397,0.008276213,0.0020286446,0.11169692],"study_design_scores_gemma":[0.035261486,0.0019497945,0.9473321,0.00031500182,0.000029482628,0.0000010752199,0.0015593114,0.000037135997,0.011873033,0.0006828955,0.00039234114,0.000566381],"about_ca_topic_score_codex":0.00010152378,"about_ca_topic_score_gemma":0.0005765825,"teacher_disagreement_score":0.23781693,"about_ca_system_score_codex":0.00003848321,"about_ca_system_score_gemma":0.00016255173,"threshold_uncertainty_score":0.99993277},"labels":[],"label_agreement":null},{"id":"W7118064860","doi":"10.1093/geroni/igaf122.1566","title":"sTNFR1 is Associated with Depressive Symptoms in Community-Dwelling Older Adults: A Logistic Regression Analysis","year":2025,"lang":"en","type":"article","venue":"Innovation in Aging","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Depression (economics); Logistic regression; Psychological intervention; Dementia; Biomarker; Cognition; Demographics; Depressive symptoms","score_opus":0.02565475111469186,"score_gpt":0.3047123113952952,"score_spread":0.27905756028060336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7118064860","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910324,0.000041084895,0.0067584794,0.00042663506,0.00005749264,0.00020341796,0.000005909321,0.000070828435,0.001403705],"genre_scores_gemma":[0.99749666,0.0000068083664,0.00005453968,0.002214415,0.0000047263543,0.000030597454,0.000026345939,0.000009633192,0.00015627759],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984665,0.00032660138,0.00045079997,0.00030058733,0.0002146611,0.00024084879],"domain_scores_gemma":[0.9987302,0.00063142343,0.00023983503,0.000275916,0.000109584,0.000013079972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040855524,0.00014177813,0.00022875202,0.001728576,0.00018514383,0.00006999481,0.0002559407,0.00008072308,0.000027973083],"category_scores_gemma":[0.0013388937,0.0001246143,0.000027668002,0.011581293,0.000089207824,0.00018945133,0.00007449807,0.00052614545,0.0000023107143],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016032747,0.00067945797,0.944736,0.00012638152,0.00012635386,0.00007142199,0.013813159,0.011461961,0.010693525,0.0050028097,0.00025053712,0.012878073],"study_design_scores_gemma":[0.0065609547,0.0000575066,0.85325676,0.005580207,0.00007950231,0.0000019654217,0.0050771623,0.067641705,0.05748465,0.0035545966,0.00008123265,0.0006237441],"about_ca_topic_score_codex":0.000263909,"about_ca_topic_score_gemma":0.00038103602,"teacher_disagreement_score":0.09147922,"about_ca_system_score_codex":0.00013302638,"about_ca_system_score_gemma":0.000049968818,"threshold_uncertainty_score":0.55644274},"labels":[],"label_agreement":null},{"id":"W7120570317","doi":"","title":"Could immunotherapy be a hope for addiction treatment?","year":2024,"lang":"en","type":"article","venue":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Immunotherapy; Addiction; Disease; MEDLINE","score_opus":0.03388830716066382,"score_gpt":0.2757698202739393,"score_spread":0.2418815131132755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7120570317","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.29990035,0.011546037,0.04497195,0.18852015,0.014957962,0.00872021,0.0022344096,0.009057941,0.420091],"genre_scores_gemma":[0.99457026,0.0005948761,0.0009767428,0.0008418771,0.0005957321,0.0007127972,0.000119743745,0.000086414235,0.001501569],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971969,0.00021310845,0.00047614935,0.0009428146,0.00050298485,0.00066803547],"domain_scores_gemma":[0.9984583,0.0005674988,0.00013345228,0.0004644787,0.00011517817,0.00026107873],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026260328,0.00043290193,0.00034324793,0.00042626355,0.00067428884,0.00046277852,0.0004293697,0.00035394728,0.00009868564],"category_scores_gemma":[0.00039201835,0.00037904817,0.00036432417,0.0007367458,0.000033257482,0.00054313755,0.00006122778,0.00031761092,0.000029895727],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039366353,0.0005081703,0.000012625015,0.000065356064,0.00011579272,0.00010374121,0.0012848835,0.000036924645,0.12738481,0.8442972,0.0045114933,0.021285357],"study_design_scores_gemma":[0.0014587069,0.0002505244,0.00022234637,0.000080933045,0.000038978837,0.00040673037,0.0001261139,0.0015935915,0.034135845,0.0008387432,0.9604515,0.00039602368],"about_ca_topic_score_codex":9.0472196e-7,"about_ca_topic_score_gemma":0.000045673452,"teacher_disagreement_score":0.95593995,"about_ca_system_score_codex":0.0006284685,"about_ca_system_score_gemma":0.0004960926,"threshold_uncertainty_score":0.9998661},"labels":[],"label_agreement":null},{"id":"W7132885122","doi":"","title":"Exploring the biological correlates of post-stroke depression","year":2008,"lang":"","type":"dissertation","venue":"TSpace","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Heart and Stroke Foundation of Canada","keywords":"Kynurenine; Depression (economics); Kynurenine pathway; Stroke (engine); Stimulation; Depressive symptoms; Post-stroke depression; Cognition; Univariate analysis","score_opus":0.09199409882202397,"score_gpt":0.31611400573403153,"score_spread":0.22411990691200756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132885122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901003,0.0018471684,0.000026377335,0.00017558511,0.0021467567,0.0006083546,0.000032235817,0.00007823575,0.004984946],"genre_scores_gemma":[0.9802071,0.010302573,0.000036625614,0.00015538586,0.000094924355,0.000077425844,0.000051348256,0.00004756671,0.0090270825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970343,0.00036248652,0.0005641858,0.00085414585,0.00060508534,0.0005797769],"domain_scores_gemma":[0.997252,0.0012198585,0.0005899427,0.00065464305,0.00015233332,0.00013122581],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017265865,0.00052646926,0.00054227083,0.00019383481,0.0006381012,0.000049262006,0.0009486806,0.00034434514,0.00033778057],"category_scores_gemma":[0.0016638844,0.0003424024,0.0004062295,0.00048728354,0.0005778627,0.00022279036,0.0001594427,0.0008889496,0.00016867797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006659435,0.0002726809,0.003764053,0.000096196956,0.000026209862,0.000033964036,0.02836301,0.00009833083,0.9523459,0.00022266193,0.0001273439,0.01398369],"study_design_scores_gemma":[0.0006705682,0.00045041295,0.12134711,0.00034013067,0.00003523598,0.000043043918,0.03599234,0.00018376886,0.83909494,0.000033457076,0.0012611803,0.0005478203],"about_ca_topic_score_codex":0.00016090837,"about_ca_topic_score_gemma":0.000026010941,"teacher_disagreement_score":0.11758305,"about_ca_system_score_codex":0.000028572278,"about_ca_system_score_gemma":0.00014177323,"threshold_uncertainty_score":0.9999028},"labels":[],"label_agreement":null},{"id":"W7132943410","doi":"","title":"Neuroimaging Gliosis in Peripheral Inflammatory Diseases of COVID-19 and Inflammatory Bowel Disease","year":2025,"lang":"","type":"dissertation","venue":"TSpace","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Gliosis; Translocator protein; Astrogliosis; Neuroinflammation; Neuroimaging; Inflammatory bowel disease; Inflammation; Microglia","score_opus":0.017018575751512062,"score_gpt":0.3112475263833694,"score_spread":0.29422895063185733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132943410","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866768,0.008362152,0.000035736182,0.0013015653,0.00086908584,0.0013762256,0.00015030196,0.00014363558,0.0010844683],"genre_scores_gemma":[0.99119776,0.0027260964,0.000018746345,0.0016565896,0.00007369472,0.00015055889,0.000090582456,0.00009197017,0.003993992],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9948844,0.0006970759,0.0010830725,0.0016665527,0.0008193901,0.00084956054],"domain_scores_gemma":[0.99629134,0.00083350437,0.00073006394,0.00090037624,0.00011064949,0.0011340922],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025319686,0.00092823996,0.0008435711,0.0011646248,0.00040667012,0.00021859985,0.0007852943,0.00028782478,0.00031998754],"category_scores_gemma":[0.0046604276,0.0010863148,0.0003428324,0.0010103929,0.0007238495,0.0005067101,0.00031517041,0.0007397888,0.000009074731],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007814336,0.0016506469,0.8046021,0.04479795,0.0001329287,0.0021789202,0.056546517,0.005595822,0.06270042,0.0069564707,0.0019582626,0.0050656158],"study_design_scores_gemma":[0.0043730102,0.00012445859,0.9586443,0.001837975,0.00025037598,0.0000065978093,0.018445693,0.0067486977,0.004084913,0.00090849766,0.00287628,0.0016992335],"about_ca_topic_score_codex":0.000260052,"about_ca_topic_score_gemma":0.00041607974,"teacher_disagreement_score":0.15404215,"about_ca_system_score_codex":0.00025405354,"about_ca_system_score_gemma":0.002982762,"threshold_uncertainty_score":0.9991587},"labels":[],"label_agreement":null},{"id":"W7132975255","doi":"","title":"The Application of Novel Positron Emission Tomography (PET) Radioligands as Imaging Biomarkers of Neurochemical Changes in the Brain: Relevance in Schizophrenia and Alzheimer&apos;s disease","year":2014,"lang":"","type":"dissertation","venue":"TSpace","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Alzheimer's Society","keywords":"Biomarker; Translocator protein; Imaging biomarker; Schizophrenia (object-oriented programming); Neurochemical; Positron emission tomography; Psychosis; White matter; Neuroimaging","score_opus":0.016217896128727583,"score_gpt":0.3189452678287677,"score_spread":0.3027273717000401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132975255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98658156,0.006169208,0.0001391043,0.004965708,0.00014617865,0.0013412794,0.0000128278125,0.000023136055,0.0006210184],"genre_scores_gemma":[0.9975937,0.0016050931,0.00009645889,0.00035688363,0.000039008464,0.0001117555,0.00003909531,0.00006680796,0.0000911855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970905,0.0003453418,0.0005928929,0.0009074433,0.0005930805,0.0004707476],"domain_scores_gemma":[0.9964171,0.0018299498,0.00077328895,0.0007601518,0.000063420586,0.00015608253],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006241542,0.00047172492,0.00047028103,0.00047623803,0.00019735876,0.00007882372,0.0009052316,0.00012514381,0.0000048621037],"category_scores_gemma":[0.001391588,0.00034924844,0.00014887654,0.0015519715,0.000690887,0.00010941649,0.000094620314,0.00045934503,0.0000010596783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028738359,0.00033312803,0.0031682167,0.00034194347,0.000024605255,0.00000708665,0.0033295,0.000011296317,0.966611,0.0009977255,0.00016952399,0.022132108],"study_design_scores_gemma":[0.008792357,0.00046078186,0.2062647,0.0025860867,0.0003225075,0.000058514775,0.012221434,0.03005245,0.73323107,0.001351522,0.0031168524,0.0015417103],"about_ca_topic_score_codex":0.00023320383,"about_ca_topic_score_gemma":0.00021107795,"teacher_disagreement_score":0.23337995,"about_ca_system_score_codex":0.000019573046,"about_ca_system_score_gemma":0.000115304254,"threshold_uncertainty_score":0.99989593},"labels":[],"label_agreement":null},{"id":"W7132988778","doi":"","title":"Astroglia Dysfunction in the Behavioural and Cellular Changes Associated with Chronic Stress","year":2024,"lang":"","type":"dissertation","venue":"TSpace","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; Campbell Family Mental Health Research Institute; Yale University; National Institutes of Health; National Alliance for Research on Schizophrenia and Depression","keywords":"Astrocyte; Chronic stress; Glial fibrillary acidic protein; Prefrontal cortex; Astrogliosis; Allostasis; Neuroplasticity; Neuroglia","score_opus":0.024379675277308284,"score_gpt":0.2808356727590013,"score_spread":0.256455997481693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132988778","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925382,0.003490078,0.000010592392,0.0012485363,0.0009209667,0.0009826047,0.00004543902,0.000078790756,0.00068477646],"genre_scores_gemma":[0.9890571,0.0002681677,0.0000032467128,0.00013454213,0.000112616726,0.00013236125,0.00032887972,0.000075708,0.009887352],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9970651,0.00037552844,0.00025570704,0.00095191196,0.0007008647,0.000650871],"domain_scores_gemma":[0.9989941,0.00023780431,0.00027241226,0.00035658205,0.00005288074,0.00008623589],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003077936,0.0005641766,0.00038050767,0.00028553634,0.00030114918,0.00044518767,0.00039176244,0.0003665113,0.00015871505],"category_scores_gemma":[0.00014366565,0.00040869036,0.00007988768,0.0009838082,0.00024784863,0.00013959802,0.000050069033,0.0011078389,0.00003795506],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020274087,0.0029766173,0.03888742,0.0041933064,0.00042613957,0.0024372512,0.41307425,0.0005136879,0.49734807,0.0026623227,0.002043709,0.033409838],"study_design_scores_gemma":[0.007448687,0.0067004785,0.44944933,0.0075565735,0.0012213375,0.00006499777,0.23046075,0.005914117,0.28595278,0.00020574965,0.0017078839,0.0033173081],"about_ca_topic_score_codex":0.00079500757,"about_ca_topic_score_gemma":0.034183964,"teacher_disagreement_score":0.41056192,"about_ca_system_score_codex":0.00021002998,"about_ca_system_score_gemma":0.00019876372,"threshold_uncertainty_score":0.9998365},"labels":[],"label_agreement":null},{"id":"W7133013673","doi":"","title":"Advancing Precision Medicine in Clinical Depression: Insights from the (Epi)genomics of the Stress System","year":2025,"lang":"","type":"dissertation","venue":"TSpace","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation","keywords":"Antidepressant; dNaM; Major depressive disorder; Serotonin transporter; Precision medicine; DNA methylation; Gene; Fluoxetine; Drug development","score_opus":0.027697319661024414,"score_gpt":0.3564939903920632,"score_spread":0.3287966707310388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133013673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9771523,0.0072362297,0.00016552936,0.00090993405,0.006919178,0.0016582125,0.000047958874,0.000036782712,0.0058739],"genre_scores_gemma":[0.9951924,0.0017916117,0.00004697117,0.00038434373,0.00033245372,0.000037887366,0.000047179667,0.00004329874,0.0021238609],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9933659,0.0020181523,0.001923191,0.0012520481,0.0009952171,0.0004455115],"domain_scores_gemma":[0.988614,0.0077949115,0.0015504417,0.0017575733,0.00015855217,0.00012448063],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007705389,0.00057067384,0.0011125493,0.00017243708,0.00045252137,0.000052841675,0.0022883017,0.00063808623,0.00007702846],"category_scores_gemma":[0.0051348647,0.00031091852,0.00036796692,0.001235956,0.00043850247,0.00012347127,0.000461068,0.001460584,0.000011785478],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010038749,0.0031972951,0.102154665,0.0067894426,0.00048959005,0.00020500329,0.3040522,0.012930492,0.40260983,0.0075460374,0.01026194,0.13972475],"study_design_scores_gemma":[0.006265016,0.0003293381,0.57997143,0.04159024,0.00039158246,0.0000050903213,0.20425394,0.009594746,0.15077193,0.0007750617,0.005048467,0.0010031583],"about_ca_topic_score_codex":0.0016762195,"about_ca_topic_score_gemma":0.0052082147,"teacher_disagreement_score":0.47781676,"about_ca_system_score_codex":0.00017146717,"about_ca_system_score_gemma":0.00064437574,"threshold_uncertainty_score":0.9999343},"labels":[],"label_agreement":null},{"id":"W7133057974","doi":"","title":"Neuroimaging of Brain Iron in Schizophrenia","year":2023,"lang":"","type":"dissertation","venue":"TSpace","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Schizophrenia (object-oriented programming); Substantia nigra; Neuroimaging; Grey matter; Pathophysiology; Psychosis","score_opus":0.0295366296650787,"score_gpt":0.3384740234059946,"score_spread":0.3089373937409159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133057974","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893506,0.0003340241,0.0000109921175,0.0017528834,0.0018520813,0.0006748605,0.000015269434,0.00014323709,0.0058660232],"genre_scores_gemma":[0.9701372,0.00039665872,0.00007023893,0.0004189177,0.000082467515,0.00003141067,0.000065033244,0.0001715737,0.028626505],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995969,0.000392053,0.00081745716,0.0012698952,0.00074537325,0.0008062511],"domain_scores_gemma":[0.9974902,0.000980358,0.0006077177,0.00071210694,0.000060410912,0.00014920525],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038490663,0.0006044634,0.0007351017,0.0010399541,0.00014412611,0.00009584974,0.0008599829,0.00032985825,0.00031711272],"category_scores_gemma":[0.0024014553,0.00071382296,0.00025752737,0.0025041895,0.00025488195,0.00019742343,0.00014507477,0.0009773383,0.00045623054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095374737,0.0003500604,0.00062584,0.0013835405,0.000009971523,0.0002147911,0.031934723,0.0005432364,0.94073576,0.0012821554,0.0022314952,0.019734683],"study_design_scores_gemma":[0.010664247,0.0008265728,0.3618846,0.0038128193,0.0000874064,0.000028632676,0.07315098,0.009552595,0.53153557,0.0020627414,0.0029314102,0.0034624143],"about_ca_topic_score_codex":0.0008150874,"about_ca_topic_score_gemma":0.0009947366,"teacher_disagreement_score":0.40920016,"about_ca_system_score_codex":0.000064462605,"about_ca_system_score_gemma":0.00033749532,"threshold_uncertainty_score":0.99953127},"labels":[],"label_agreement":null},{"id":"W7133064785","doi":"","title":"Understanding Brain Transcriptome Signatures Associated with Disparate Psychiatric Outcomes in Black American Populations","year":2023,"lang":"","type":"dissertation","venue":"TSpace","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Krembil Foundation","keywords":"Transcriptome; Schizophrenia (object-oriented programming); Mechanism (biology); Gene; Immune system; Cohort; Social stress; Diversity (politics)","score_opus":0.09764616515688397,"score_gpt":0.364520294368435,"score_spread":0.26687412921155107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133064785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891058,0.0001199198,0.0005869053,0.0050170748,0.0013992661,0.0014983042,0.00010784023,0.00040648837,0.001758366],"genre_scores_gemma":[0.9736102,0.00017829587,0.000056525725,0.0008298857,0.000044728953,0.000078051664,0.00046063698,0.00025732216,0.02448433],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9941646,0.0007016343,0.000901763,0.001633086,0.0011968508,0.0014020925],"domain_scores_gemma":[0.99672335,0.0012980178,0.0010268757,0.00058784656,0.00006916125,0.0002947292],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003917766,0.001091696,0.0013234048,0.0017730454,0.00061775546,0.00036131506,0.00076068414,0.00049092463,0.00013739956],"category_scores_gemma":[0.0012073362,0.0010273339,0.0003890964,0.007979998,0.0006497465,0.00031725602,0.000034712226,0.0015073762,0.00012504258],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034836826,0.0054047937,0.4175528,0.0011014,0.0011332954,0.0007135562,0.39058566,0.06620016,0.06656458,0.03128046,0.014922935,0.0010566897],"study_design_scores_gemma":[0.0031435476,0.0006386175,0.9096114,0.00054622523,0.00015726736,0.0000012689619,0.07927609,0.0027516214,0.00028886276,0.0018669682,0.00004446151,0.0016736415],"about_ca_topic_score_codex":0.001431358,"about_ca_topic_score_gemma":0.041507483,"teacher_disagreement_score":0.49205863,"about_ca_system_score_codex":0.000654467,"about_ca_system_score_gemma":0.00035921432,"threshold_uncertainty_score":0.9992177},"labels":[],"label_agreement":null},{"id":"W7133091093","doi":"","title":"Relationship between Serum 4-Hydroxynonenal and Agitation Severity in Moderate-to-severe Alzheimer’s Disease","year":2024,"lang":"","type":"dissertation","venue":"TSpace","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Disinhibition; Disease; Pathogenesis; Oxidative stress; Severity of illness; Clinical trial; Adverse effect; Psychomotor agitation","score_opus":0.06273529700406338,"score_gpt":0.3545609835405068,"score_spread":0.2918256865364434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133091093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881659,0.0021923017,0.00009730005,0.004475602,0.0007531045,0.001646148,0.00023407002,0.00016384774,0.0022717072],"genre_scores_gemma":[0.9898472,0.00010136162,0.00012255834,0.0007137854,0.0001649638,0.00012636057,0.00043368115,0.00013824488,0.008351874],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99520546,0.00048174633,0.0007796536,0.0018861534,0.00082143495,0.0008255709],"domain_scores_gemma":[0.99725443,0.0010116718,0.00026382765,0.000556842,0.0001335529,0.0007796719],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041096154,0.0008263556,0.00065589807,0.00088296423,0.00047900528,0.00060503447,0.00041681493,0.0005121536,0.00015078149],"category_scores_gemma":[0.0017296436,0.00095010723,0.00018295099,0.0017376844,0.00017133185,0.00062461745,0.00016581002,0.0013164763,0.00066645845],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008050615,0.0014026208,0.66520876,0.0074308873,0.0003490869,0.0011846904,0.2466264,0.016252374,0.00497476,0.0150918085,0.0074489485,0.025979016],"study_design_scores_gemma":[0.0010646913,0.00011966521,0.97071373,0.00076834083,0.0003020346,0.000006015094,0.005874951,0.008521535,0.0012730331,0.009753469,0.00033148326,0.0012710427],"about_ca_topic_score_codex":0.00029535123,"about_ca_topic_score_gemma":0.00071274285,"teacher_disagreement_score":0.30550495,"about_ca_system_score_codex":0.00015390787,"about_ca_system_score_gemma":0.0005985347,"threshold_uncertainty_score":0.99929494},"labels":[],"label_agreement":null},{"id":"W7135680493","doi":"","title":"Network Analysis of Inflammation and Symptoms in Recent Onset Schizophrenia and the Influence of Minocycline During a Clinical Trial","year":2023,"lang":"en","type":"article","venue":"Research Portal (King's College London)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre","funders":"Medical Research Council; National Institute for Health and Care Research; Australian Government","keywords":"Minocycline; Placebo; Schizophrenia (object-oriented programming); Clinical trial; Pathological; Immune system; Inflammation; Perspective (graphical)","score_opus":0.06018897480919799,"score_gpt":0.37263959114589673,"score_spread":0.31245061633669874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7135680493","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979473,0.00012187046,6.8978386e-7,0.00045593726,0.000046899502,0.0009345487,0.000031102052,0.00002686051,0.0004348257],"genre_scores_gemma":[0.99845093,0.0011433805,0.000021164427,0.000024533809,0.00006070575,0.00005343345,0.000005643947,0.000015399432,0.00022483309],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9965813,0.0010152482,0.00085399556,0.00043466434,0.0006995913,0.00041520735],"domain_scores_gemma":[0.996401,0.0028168825,0.00025524036,0.00033443893,0.000090572365,0.00010186218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0034123843,0.00012272694,0.0005056744,0.0008138858,0.00014684147,0.00003436561,0.00027475116,0.00010222155,0.000043699572],"category_scores_gemma":[0.005408714,0.00009410612,0.00010102139,0.005373637,0.0010704406,0.0001298502,0.0003180937,0.00036953058,0.000004280147],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.26735377,0.0011576624,0.5639442,0.00076714513,0.0012847593,0.0010056348,0.0026682303,0.017692832,0.060829744,0.049912456,0.0013676188,0.03201594],"study_design_scores_gemma":[0.044919915,0.0004159189,0.94029105,0.00016565577,0.00007300162,0.000007653261,0.000249583,0.008892668,0.0027295924,0.0018499607,0.00021280337,0.00019220836],"about_ca_topic_score_codex":0.00010577121,"about_ca_topic_score_gemma":0.0008737007,"teacher_disagreement_score":0.37634686,"about_ca_system_score_codex":0.000011872238,"about_ca_system_score_gemma":0.00011609705,"threshold_uncertainty_score":0.6475126},"labels":[],"label_agreement":null},{"id":"W7144485364","doi":"","title":"Implications of Systemic Inflammation and Periodontitis for Major Depression","year":2018,"lang":"en","type":"article","venue":"Institutional Repositories DataBase (IRDB)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of British Columbia","keywords":"Periodontitis; Systemic inflammation; Inflammation; Depression (economics); Neuroinflammation; Risk factor; Cytokine; Tumor necrosis factor alpha; Proinflammatory cytokine","score_opus":0.022445055902561295,"score_gpt":0.27752386560628284,"score_spread":0.25507880970372154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7144485364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.974483,0.00023587246,0.020412209,0.00026200304,0.0008377235,0.00050813437,0.00074321753,0.00007255939,0.0024452808],"genre_scores_gemma":[0.9974335,0.00004387047,0.0017310238,0.000051122523,0.00042931346,0.00010329863,0.00009788276,0.00000828132,0.00010169681],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902797,0.000032484957,0.00028020464,0.00032449834,0.00019405379,0.00014076948],"domain_scores_gemma":[0.9991584,0.0001695078,0.00014204059,0.0002948561,0.0001719475,0.00006326614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009396389,0.00010347837,0.00011842121,0.00007657268,0.00055052724,0.00006239331,0.00015646643,0.00005156422,0.000012926842],"category_scores_gemma":[0.0008682854,0.00009551797,0.000036953126,0.0001716633,0.000517226,0.00055624,0.00009481039,0.000048606824,0.0000073776077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007305418,0.000026496598,0.002468586,0.00010807964,0.0000054371944,0.0000020265873,0.00016572975,0.0000049071923,0.8828233,0.112107635,0.00057957595,0.0016352073],"study_design_scores_gemma":[0.00072109106,0.000079737096,0.014886688,0.00026705337,0.000017736163,0.00027879278,0.00009018741,0.00018264758,0.9648257,0.0010845894,0.017393416,0.0001723614],"about_ca_topic_score_codex":0.000063301304,"about_ca_topic_score_gemma":0.000040741317,"teacher_disagreement_score":0.111023046,"about_ca_system_score_codex":0.000041772062,"about_ca_system_score_gemma":0.00014629534,"threshold_uncertainty_score":0.4234266},"labels":[],"label_agreement":null},{"id":"W7161976922","doi":"10.82308/14973","title":"Determining the risk of depressive disorder as a sequela of a foodborne infection using administrative data from British Columbia, Canada : a retrospective population-based cohort study","year":2022,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Sequela; Public health; Retrospective cohort study; Cohort study","score_opus":0.03508079264967377,"score_gpt":0.3120791111126807,"score_spread":0.27699831846300693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7161976922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99147516,0.000037839814,0.000027191949,0.0000038918306,0.00039256038,0.0022052613,0.005058157,0.000030475816,0.00076947146],"genre_scores_gemma":[0.9966561,0.000014996773,0.0000356733,0.000057722667,0.000022474565,0.00014093424,0.0026775775,0.000050512353,0.00034397581],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99639153,0.0006970059,0.000673194,0.0010081632,0.001002407,0.00022769129],"domain_scores_gemma":[0.9965505,0.00092299725,0.0014176093,0.00085177686,0.00020190162,0.000055225883],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022544814,0.0002542202,0.0005809311,0.00007034862,0.00059249863,0.00015591145,0.0006677809,0.000116135205,0.0006519255],"category_scores_gemma":[0.0029920612,0.00030946423,0.000102600876,0.0006210885,0.000078767756,0.00019582633,0.00014759417,0.00049956044,4.3384992e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000074342424,0.00041427478,0.99789006,0.000027579375,0.00015143538,0.000015290705,0.0004111443,0.00025341165,0.00019865065,0.000002721965,0.00015816287,0.00040293392],"study_design_scores_gemma":[0.0010285018,0.0003209925,0.9916311,0.000064527056,0.0003151931,0.0000017851498,0.0038080055,0.0018285,0.0005327478,0.00015653054,0.000014332237,0.00029779738],"about_ca_topic_score_codex":0.99642336,"about_ca_topic_score_gemma":0.9994535,"teacher_disagreement_score":0.006258965,"about_ca_system_score_codex":0.00030543952,"about_ca_system_score_gemma":0.0019340261,"threshold_uncertainty_score":0.99993575},"labels":[],"label_agreement":null},{"id":"W7162033209","doi":"10.82308/48122","title":"Applying integrative geneset-embedded non-negative matrix factorization to discovery of biomarkers for major depressive disorder antidepressant response","year":2023,"lang":"en","type":"dissertation","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Major depressive disorder; Interpretability; Matrix decomposition; Antidepressant; Biomarker; Non-negative matrix factorization; Cohort; Comorbidity","score_opus":0.020436067703255966,"score_gpt":0.32451869960460633,"score_spread":0.3040826319013504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7162033209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9561761,0.00006846941,0.031389464,0.00009426733,0.0015203226,0.007837616,0.0016285235,0.00023244982,0.0010527603],"genre_scores_gemma":[0.96784717,0.00008675213,0.0013667019,0.00012607157,0.000068492736,0.0035211346,0.0009657875,0.00021887633,0.025798988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99645925,0.0003116629,0.0007870688,0.0012628658,0.0006236065,0.00055556226],"domain_scores_gemma":[0.9953173,0.003074592,0.00067376805,0.0005159899,0.00028456206,0.00013381735],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024032588,0.00067119685,0.00077354553,0.00086969644,0.00029739444,0.0001789959,0.0006547733,0.00037575062,0.000047624028],"category_scores_gemma":[0.005555964,0.00055038487,0.0003787686,0.0013949986,0.000116205076,0.0005013195,0.000112789356,0.00024183204,0.000041248535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012497017,0.00023815826,0.00043671828,0.0005685733,0.0002049484,0.000012560443,0.008997421,0.00028337148,0.96889603,0.0005541451,0.0034285802,0.0038824487],"study_design_scores_gemma":[0.0017977523,0.00032592443,0.009223919,0.00043151272,0.00007922758,9.895181e-7,0.021465957,0.0008236961,0.9635936,0.0012558971,0.00023641472,0.0007650982],"about_ca_topic_score_codex":0.00025324465,"about_ca_topic_score_gemma":0.0007052064,"teacher_disagreement_score":0.03002276,"about_ca_system_score_codex":0.00009297788,"about_ca_system_score_gemma":0.00031174644,"threshold_uncertainty_score":0.99969476},"labels":[],"label_agreement":null},{"id":"W72004537","doi":"10.1016/b978-0-08-045396-5.00187-1","title":"Cytokine Effects on Neuronal Processes and on Behavior","year":2010,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Neuroscience; Cytokine; Psychology; Biology; Cell biology; Immunology","score_opus":0.017823019720540085,"score_gpt":0.24676653947103583,"score_spread":0.22894351975049573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W72004537","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.023688955,0.00008549008,2.1616377e-7,0.00011680342,0.00055702653,0.00093842956,0.00006114524,0.00014008454,0.97441185],"genre_scores_gemma":[0.05172173,0.00008461061,0.000026791673,0.004684313,0.00039468697,0.00011838596,0.0000070267415,0.00014634212,0.94281614],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99812615,0.00003087906,0.00022103087,0.00085137883,0.0004565138,0.00031403592],"domain_scores_gemma":[0.9987501,0.00046618498,0.00015545895,0.00043535687,0.00003101562,0.00016187338],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000056669276,0.0005101285,0.00037684847,0.00017885263,0.00018050705,0.00008475723,0.00030979712,0.00033281726,0.00011393095],"category_scores_gemma":[0.0002325146,0.00043189127,0.000102484024,0.00001798788,0.0002863749,0.000035646044,0.000100576355,0.00096306857,0.00026632703],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006593092,0.000042705306,0.0000027303715,0.0002518339,0.0000046881473,0.00015012587,0.000058298585,4.4875755e-8,0.032815184,0.004275631,0.000060342834,0.96227247],"study_design_scores_gemma":[0.0006071246,0.000689579,0.0002246537,0.00040802505,0.000043725766,0.000038125716,7.4280075e-7,2.7822477e-7,0.1661033,0.0035616222,0.8277747,0.00054810505],"about_ca_topic_score_codex":9.884261e-8,"about_ca_topic_score_gemma":0.000008550056,"teacher_disagreement_score":0.9617244,"about_ca_system_score_codex":0.000017596198,"about_ca_system_score_gemma":0.00008576315,"threshold_uncertainty_score":0.99981326},"labels":[],"label_agreement":null},{"id":"W81425843","doi":"","title":"Cytokines, cancer and depression: connecting the dots.","year":2005,"lang":"en","type":"article","venue":"PubMed","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medicine; Depression (economics); Cancer; Oncology; Internal medicine","score_opus":0.03381052752867166,"score_gpt":0.251626824446274,"score_spread":0.21781629691760232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W81425843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9838835,0.0010014519,0.000014295024,0.005807747,0.0002178614,0.0002968317,0.000004132838,0.00007635567,0.008697854],"genre_scores_gemma":[0.99539167,0.00012675131,0.000014501238,0.0033320184,0.00022771995,0.00032435905,1.278108e-7,0.0000080854325,0.000574741],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99938715,0.000030130805,0.00007086349,0.00019140376,0.00010000065,0.00022042899],"domain_scores_gemma":[0.99962175,0.00016820601,0.000032621752,0.00011769568,0.000006876487,0.000052868003],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009118366,0.00006304729,0.000054139204,0.000018264343,0.0001775298,0.00005337397,0.00013216358,0.000022911063,0.00003557398],"category_scores_gemma":[0.00037841898,0.00003873488,0.000017433811,0.00010925741,0.00006105115,0.000100141784,0.000059619157,0.00008041921,0.0000066360717],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011975693,0.000014511894,0.0020023764,0.0000042140764,0.0000018028916,0.000002077951,0.00024517355,0.000035154957,0.0030711663,0.00030259416,0.0018730953,0.9924359],"study_design_scores_gemma":[0.0009768264,0.0000039886736,0.4209721,0.00000866445,0.000008039388,0.00003816643,0.0002514196,0.00040536028,0.22361355,0.0004178763,0.35306743,0.00023656666],"about_ca_topic_score_codex":0.000023456756,"about_ca_topic_score_gemma":0.000068176065,"teacher_disagreement_score":0.9921993,"about_ca_system_score_codex":0.000011275664,"about_ca_system_score_gemma":0.000005651963,"threshold_uncertainty_score":0.15795626},"labels":[],"label_agreement":null},{"id":"W829641811","doi":"","title":"The role of monocytes, macrophages and the microbiota in age-associated inflammation during the steady state and anti-bacterial immunity","year":2014,"lang":"en","type":"dissertation","venue":"MacSphere (McMaster University)","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Pfizer; McMaster University; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University; Pfizer Canada; Lung Health Foundation; Canadian Thoracic Society; University of Pennsylvania","keywords":"Inflammation; Immunology; Immunity; Macrophage; Microbiology; Biology; Immune system; Medicine; Genetics","score_opus":0.005877618839156127,"score_gpt":0.18574667293292113,"score_spread":0.179869054093765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W829641811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9819223,0.00026161247,7.9510755e-7,0.000066335626,0.00013100481,0.00047492934,0.00002725418,0.0000170174,0.01709872],"genre_scores_gemma":[0.9460962,0.0007457882,0.0000025772094,0.000013995324,0.000015450998,0.0000015946586,0.000020824436,0.000019171237,0.053084444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983777,0.00071736035,0.00023631885,0.00027900544,0.00014633767,0.00024331664],"domain_scores_gemma":[0.9988522,0.00045892803,0.00037418972,0.00024976683,0.00003547171,0.000029444489],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023768861,0.00022554408,0.00027187204,0.00008465879,0.000511926,0.00018034405,0.00048816792,0.00013057188,0.0003138484],"category_scores_gemma":[0.000120966324,0.00014274722,0.00006210789,0.00031988102,0.00043101888,0.00014535991,0.00017076336,0.00035754152,0.0000031155414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002748983,0.00006585612,0.0018541028,0.0002223748,0.00010017281,0.00003163558,0.011642979,0.000051680432,0.84049,0.0016288738,0.000019062414,0.14114432],"study_design_scores_gemma":[0.01686438,0.00015407901,0.43237495,0.0005697645,0.00019498094,0.000012473387,0.04072629,0.0004475059,0.45463285,0.0017242483,0.05117616,0.0011223278],"about_ca_topic_score_codex":0.00047590924,"about_ca_topic_score_gemma":0.005455535,"teacher_disagreement_score":0.43052086,"about_ca_system_score_codex":0.000048745962,"about_ca_system_score_gemma":0.00003666712,"threshold_uncertainty_score":0.58210623},"labels":[],"label_agreement":null},{"id":"W984827913","doi":"10.1016/j.autrev.2015.07.011","title":"Immunological GABAergic interactions and therapeutic applications in autoimmune diseases","year":2015,"lang":"en","type":"review","venue":"Autoimmunity Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":127,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"GABAergic; Glutamate decarboxylase; Experimental autoimmune encephalomyelitis; Immune system; Receptor; Immunology; gamma-Aminobutyric acid; Autoimmunity; Chemistry; Pharmacology; Biology; Medicine; Internal medicine; Biochemistry","score_opus":0.16159963574422653,"score_gpt":0.3918869174084757,"score_spread":0.23028728166424917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W984827913","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000027516127,0.9948787,0.000019176307,0.000050931605,0.00016384874,0.0028912937,0.000064423955,0.00017415315,0.0017299647],"genre_scores_gemma":[0.00012369131,0.99697995,0.00003908004,0.00018207838,0.00002932709,0.0016384044,0.000110303765,0.00005562122,0.0008415416],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9953598,0.002100856,0.00120724,0.00069267437,0.00019466892,0.00044475784],"domain_scores_gemma":[0.9971334,0.0009099087,0.00059295126,0.0012146154,0.00002875394,0.000120389624],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00052874757,0.0006532156,0.0025007527,0.00035054216,0.00029129515,0.00012680396,0.001001262,0.00024232354,0.00020198966],"category_scores_gemma":[0.00064615574,0.00046460936,0.0005350645,0.0012915223,0.00045626212,0.00017701823,0.000454703,0.0012614685,0.0005728074],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000024545723,0.0002933092,0.000002213372,0.0024331387,0.000013744199,0.0000038762923,0.000085358064,1.3564974e-7,0.000024598212,0.0013873054,0.00010381532,0.99565005],"study_design_scores_gemma":[0.0001911428,0.00003750906,0.00016683395,0.0033352703,0.00017214967,0.000057990113,0.00004574564,0.000006195507,0.0000010468289,0.000860817,0.9946684,0.00045685784],"about_ca_topic_score_codex":0.000037915554,"about_ca_topic_score_gemma":0.000011568487,"teacher_disagreement_score":0.9951932,"about_ca_system_score_codex":0.00018328082,"about_ca_system_score_gemma":0.00023886703,"threshold_uncertainty_score":0.99978054},"labels":[],"label_agreement":null}]}