{"meta":{"query_hash":"3e3d8a1765aa","filters":{"venue":"ACS Bio & Med Chem Au"},"cohort_total":18,"direct_labels_cover":0,"predictions_cover":18,"exported":18,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/3e3d8a1765aa","api":"https://metacan.xera.ac/api/v1/cohort?venue=ACS+Bio+%26+Med+Chem+Au"},"results":[{"id":"W4292079763","doi":"10.1021/acsbiomedchemau.2c00047","title":"Shedding Light on the Elephant in a Dark Room in the Discovery of New Medicine: Highlighting Molecular Pharmaceutics within <i>ACS Bio &amp; Med Chem Au</i>","year":2022,"lang":"en","type":"editorial","venue":"ACS Bio & Med Chem Au","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Pharmacy; Citation; Library science; Medicine; Computer science; Family medicine","score_opus":0.014303487156837323,"score_gpt":0.27966725520297686,"score_spread":0.26536376804613954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292079763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8178174,0.0046502193,0.0003926007,0.004473291,0.16951258,0.0014619505,0.000156243,0.000038678707,0.0014970279],"genre_scores_gemma":[0.79911166,0.0022493277,0.00024692135,0.0013267394,0.19278522,0.00025739873,0.002386261,0.00026167708,0.0013747838],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9950371,0.00044513354,0.0011566461,0.0010442463,0.0014716818,0.00084521633],"domain_scores_gemma":[0.9973111,0.0004830561,0.00082356756,0.0011236161,0.00011509485,0.00014356915],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0029446203,0.000766996,0.0008739103,0.00020445415,0.00021545235,0.00008202185,0.001714631,0.00091081567,0.000060736867],"category_scores_gemma":[0.00149475,0.0004936978,0.00027218275,0.0006754586,0.00014036839,0.000015991784,0.0005138786,0.0015350076,0.0000033798985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021527137,0.000107291264,0.000029340354,0.000107531014,0.00016878368,0.00003292576,0.0025257037,0.00008953504,0.84084874,0.00013708942,0.15556018,0.00017760247],"study_design_scores_gemma":[0.0010631592,0.00018349194,0.0000018567696,0.00032778096,0.0001199209,0.000004521917,0.00088476826,0.000010389202,0.6892688,0.00016090804,0.30757064,0.00040372234],"about_ca_topic_score_codex":0.0006007192,"about_ca_topic_score_gemma":0.00047225427,"teacher_disagreement_score":0.15201046,"about_ca_system_score_codex":0.0003376365,"about_ca_system_score_gemma":0.001245515,"threshold_uncertainty_score":0.99975145},"labels":[],"label_agreement":null},{"id":"W4304207200","doi":"10.1021/acsbiomedchemau.2c00052","title":"Activity-Based Sensing for Chemistry-Enabled Biology: Illuminating Principles, Probes, and Prospects for Boronate Reagents for Studying Hydrogen Peroxide","year":2022,"lang":"en","type":"review","venue":"ACS Bio & Med Chem Au","topic":"Molecular Sensors and Ion Detection","field":"Chemistry","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; Canadian Institute for Advanced Research; University of California","keywords":"Hydrogen peroxide; Chemistry; Reagent; Nanotechnology; Combinatorial chemistry; Computational biology; Biology; Biochemistry; Materials science; Organic chemistry","score_opus":0.07483312613147874,"score_gpt":0.3131475603890427,"score_spread":0.23831443425756393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4304207200","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12835985,0.85020185,0.0041609155,0.000120865865,0.0004671018,0.013586707,0.0017350897,0.0006100829,0.00075752457],"genre_scores_gemma":[0.05238895,0.87249136,0.02589341,0.00017039536,0.0031020227,0.020613547,0.012250405,0.001866738,0.011223177],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968232,0.000057922,0.0007497047,0.0013037542,0.0002396673,0.00082576554],"domain_scores_gemma":[0.99740547,0.00061651337,0.0010546164,0.00060916145,0.000144971,0.00016927924],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000819618,0.0007485277,0.0015196458,0.00009536321,0.00076081,0.00008548266,0.00031729683,0.0006247999,0.000029755123],"category_scores_gemma":[0.00102286,0.0007247416,0.0006145994,0.00019885637,0.00009055553,0.00006132232,0.00020683178,0.0004501096,5.3180656e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001286042,0.00014783128,0.0000041668427,0.064006485,0.00056542206,0.000006986531,0.00012051988,0.000004709274,0.3053717,0.000011275289,0.0000500166,0.6295823],"study_design_scores_gemma":[0.0010731812,0.000067961555,9.903911e-8,0.0013334778,0.0006466491,0.000020833797,0.00004791514,0.00078065635,0.47348043,0.000029220579,0.5220215,0.0004980855],"about_ca_topic_score_codex":0.000021954544,"about_ca_topic_score_gemma":0.000010642526,"teacher_disagreement_score":0.6290842,"about_ca_system_score_codex":0.00084799586,"about_ca_system_score_gemma":0.0005131104,"threshold_uncertainty_score":0.99952036},"labels":[],"label_agreement":null},{"id":"W4308411115","doi":"10.1021/acsbiomedchemau.2c00056","title":"A Fluorescence-Based Assay to Probe Inhibitory Effect of Fructose Mimics on GLUT5 Transport in Breast Cancer Cells","year":2022,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Glycomics Network; Egyptian Cultural and Educational Bureau","keywords":"Fructose; Cancer cell; Biochemistry; Chemistry; Glucose transporter; Fructokinase; Transporter; Hexose; Cancer; Biology; Enzyme; Endocrinology","score_opus":0.005053940527679816,"score_gpt":0.22551012330232262,"score_spread":0.2204561827746428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308411115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99702847,0.00058092945,0.000024986242,0.00036855575,0.00097531686,0.0005170102,0.0003610441,0.000012560705,0.00013110857],"genre_scores_gemma":[0.9979031,0.0001414478,0.0000963274,0.00056101347,0.0006057888,0.0003187351,0.00013466924,0.000037313104,0.00020160341],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984568,0.000117320174,0.0002819064,0.00046637247,0.00030313653,0.0003745006],"domain_scores_gemma":[0.99928975,0.000022010561,0.00010364545,0.00039841761,0.000049160913,0.00013699968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042442727,0.00023677447,0.00032461123,0.00010668775,0.00006413806,0.0000048606894,0.00028360798,0.00013412481,0.000050050257],"category_scores_gemma":[0.000019724652,0.0002262849,0.00014028531,0.0002779189,0.00007300247,0.0000030410529,0.000068730114,0.00020259942,0.000002597015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009500739,0.00015739714,0.004024544,0.00009366468,0.000030958916,0.0000039996867,0.0002215244,0.0004290106,0.98652786,0.0000030655167,0.001998534,0.005559349],"study_design_scores_gemma":[0.0016027043,0.00034515475,0.004784678,0.00004649641,0.000041193558,0.0000038488765,0.000035493216,0.000010454773,0.96793216,0.0000031080049,0.024950666,0.00024401369],"about_ca_topic_score_codex":0.0004707187,"about_ca_topic_score_gemma":0.0003459257,"teacher_disagreement_score":0.022952134,"about_ca_system_score_codex":0.00012952322,"about_ca_system_score_gemma":0.00045764813,"threshold_uncertainty_score":0.92276305},"labels":[],"label_agreement":null},{"id":"W4323832771","doi":"10.1021/acsbiomedchemau.3c00001","title":"Template-Based Porous Hydrogel Microparticles as Carriers for Therapeutic Proteins","year":2023,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Hydrogels: synthesis, properties, applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada","keywords":"Bovine serum albumin; Template; Ethylene glycol; Self-healing hydrogels; Chemistry; Porosity; Nanotechnology; Controlled release; Surface charge; Drug delivery; Chemical engineering; Materials science; Biophysics; Chromatography; Polymer chemistry; Organic chemistry","score_opus":0.024805571265058748,"score_gpt":0.2655457409835462,"score_spread":0.24074016971848747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323832771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99556655,0.0004199717,0.0005229456,0.0020162056,0.00008445852,0.0009776885,0.000068001544,0.00012729695,0.00021690913],"genre_scores_gemma":[0.9961367,0.00004263842,0.00045077488,0.00067569717,0.00025979665,0.0012478193,0.00026458668,0.00007788859,0.0008440512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984745,0.000033942146,0.00027560414,0.0005095577,0.00015964644,0.00054674153],"domain_scores_gemma":[0.99897116,0.000031386357,0.0000994918,0.0006536635,0.00008906262,0.00015520837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027501068,0.00023669015,0.00019656951,0.00006165385,0.00023186022,0.00003259088,0.000365201,0.000220902,0.000015256134],"category_scores_gemma":[0.00013317428,0.00021654766,0.00012966385,0.00023778659,0.0001834586,0.0000048270745,0.00007541033,0.0000757458,0.00015444885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008520813,0.000063073014,0.00046498136,0.000037942278,0.00010331864,0.0000017779855,0.00013283618,0.000039737464,0.9941595,0.000035742152,0.0014448906,0.0034309633],"study_design_scores_gemma":[0.0005482068,0.00015606264,0.00011070653,0.000012672434,0.00005192633,0.0000058805895,0.00012375411,0.00016256253,0.926756,0.0003793478,0.071424514,0.00026837393],"about_ca_topic_score_codex":0.00013926922,"about_ca_topic_score_gemma":0.0000940219,"teacher_disagreement_score":0.06997962,"about_ca_system_score_codex":0.000058838064,"about_ca_system_score_gemma":0.00034610464,"threshold_uncertainty_score":0.88305575},"labels":[],"label_agreement":null},{"id":"W4388694686","doi":"10.1021/acsbiomedchemau.3c00039","title":"The Effect of Deuteration and Homologation of the Lactam Ring of Nirmatrelvir on Its Biochemical Properties and Oxidative Metabolism","year":2023,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Biological and Environmental Research; National Institute of General Medical Sciences; Basic Energy Sciences; Canadian Light Source; Natural Sciences and Engineering Research Council of Canada; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; Office of Science; National Institutes of Health; U.S. Department of Energy; Alberta Innovates; Alberta Innovates - Health Solutions; SLAC National Accelerator Laboratory; University of Alberta","keywords":"Chemistry; Lactam; Stereochemistry; Microsome; Metabolic stability; Lipophilicity; Biochemistry; Cysteine; Metabolism; Enzyme; In vitro","score_opus":0.015955167367523625,"score_gpt":0.24275526977111878,"score_spread":0.22680010240359516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388694686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984757,0.0010485265,0.000011180955,0.00016784991,0.0000702187,0.00016993903,0.000010212264,0.000003044568,0.000043356813],"genre_scores_gemma":[0.9991791,0.00065829814,0.000010666433,0.000018214056,0.000033470194,0.00001685575,0.000010537312,0.000006551029,0.000066308676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99955565,0.000046803307,0.00012220273,0.000109888075,0.00008254364,0.00008288548],"domain_scores_gemma":[0.99966496,0.00003609971,0.000100911675,0.0001402735,0.000042537456,0.000015229415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018896366,0.00007394757,0.00010816853,0.000016871414,0.000050883293,0.0000052868118,0.00007646826,0.00006788889,2.9505105e-7],"category_scores_gemma":[0.00006577343,0.000040681127,0.000032540527,0.00007256125,0.00011453803,0.000002676972,0.000079042366,0.000037913847,1.7220314e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094894946,0.0000066277703,0.00015145194,0.00004713525,0.000051987372,4.1930566e-8,0.00021388519,0.0000029802236,0.9964443,0.00015421103,0.000016018059,0.002816471],"study_design_scores_gemma":[0.00035594293,0.00021898527,0.000994064,0.00003097484,0.000036672554,0.0000011992752,0.000057160447,0.000066795794,0.9977305,0.000064982036,0.00040007953,0.00004264875],"about_ca_topic_score_codex":0.00000860064,"about_ca_topic_score_gemma":0.0000072146754,"teacher_disagreement_score":0.0027738223,"about_ca_system_score_codex":0.0000052416676,"about_ca_system_score_gemma":0.000021212358,"threshold_uncertainty_score":0.16589282},"labels":[],"label_agreement":null},{"id":"W4393038428","doi":"10.1021/acsbiomedchemau.4c00001","title":"Advancing <i>In Situ</i> Analysis of Biomolecular Corona: Opportunities and Challenges in Utilizing Field-Flow Fractionation","year":2024,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Field-Flow Fractionation Techniques","field":"Engineering","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"In situ; Field flow fractionation; Field (mathematics); Nanotechnology; Corona (planetary geology); Chemistry; Materials science; Fractionation; Environmental science; Physics; Astrobiology; Chromatography; Organic chemistry; Mathematics","score_opus":0.035807704328721206,"score_gpt":0.2666139499228904,"score_spread":0.23080624559416918,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393038428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92492604,0.027676377,0.02406148,0.0062668473,0.000563268,0.000332909,0.00002097675,0.0007865512,0.015365545],"genre_scores_gemma":[0.98623383,0.012618783,0.0009818737,0.000044517532,0.000024972474,0.000028003877,0.000031936972,0.00001653919,0.00001954618],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992339,0.000019242794,0.00026735218,0.0001769077,0.00015580138,0.00014679633],"domain_scores_gemma":[0.9995425,0.00023388049,0.00003038506,0.00012718924,0.00003533272,0.000030721232],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025365537,0.000113562906,0.00019823031,0.000785019,0.000016023785,0.00001718084,0.00006066074,0.00013442671,0.000029637009],"category_scores_gemma":[0.00007825965,0.0001295269,0.000046133555,0.0005252118,0.000018060644,0.00027608598,0.000020488169,0.00015783889,9.821553e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021278282,0.00008721241,0.0020496596,0.0011513022,0.000706857,0.00010678342,0.0042401245,0.0058131036,0.5562509,0.005489609,0.00048939907,0.42359382],"study_design_scores_gemma":[0.00017648039,0.00003252072,0.004483574,0.00021803855,0.00012963892,0.000005728581,0.0020282916,0.07232747,0.9110733,0.000689548,0.008584426,0.00025095427],"about_ca_topic_score_codex":0.00007604901,"about_ca_topic_score_gemma":0.0009674578,"teacher_disagreement_score":0.42334285,"about_ca_system_score_codex":0.00015358458,"about_ca_system_score_gemma":0.00002983476,"threshold_uncertainty_score":0.5281954},"labels":[],"label_agreement":null},{"id":"W4401109030","doi":"10.1021/acsbiomedchemau.4c00013","title":"Development of a Polymersome Blood Ammonia Assay Coupled with a Portable Near-Infrared Fluorometer","year":2024,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Renal function and acid-base balance","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Faculté de pharmacie, Université de Montréal; Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Fluorometer; Infrared; Ammonia; Chemistry; Polymersome; Nanotechnology; Materials science; Optics; Biochemistry; Fluorescence; Physics; Organic chemistry; Copolymer; Amphiphile","score_opus":0.010952909846101668,"score_gpt":0.23679063823284402,"score_spread":0.22583772838674235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401109030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99481964,0.00086478743,0.00029199242,0.00051878666,0.00018119291,0.00023680924,0.000008004279,0.00014140042,0.0029373888],"genre_scores_gemma":[0.9775806,0.00002316669,0.00872885,0.00035610603,0.00010125196,0.000046342026,0.000089463305,0.000038681465,0.013035523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855363,0.000012152073,0.00034657307,0.00032205923,0.00043319148,0.00033239828],"domain_scores_gemma":[0.9993022,0.000051418705,0.000080592705,0.000289382,0.000084221036,0.00019214791],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023559359,0.00020509679,0.0003650621,0.000112764,0.0000648605,0.000036313108,0.00008470883,0.000098424964,0.0003740917],"category_scores_gemma":[0.000049713595,0.0001436427,0.00007437836,0.0005218659,0.00008675414,0.0000826301,0.000029637993,0.00017433362,0.00009783884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032386917,0.00023513673,0.0045533767,0.00043252783,0.0007059477,0.00025225442,0.0013252913,8.2760835e-7,0.9860922,0.000037213653,0.0015237331,0.0045175836],"study_design_scores_gemma":[0.0016186853,0.00019026923,0.0043131816,0.0005375745,0.00023922116,0.00010940939,0.00013721529,0.00023418547,0.96790016,0.000007747709,0.024524102,0.0001882801],"about_ca_topic_score_codex":0.0000466242,"about_ca_topic_score_gemma":0.000022580178,"teacher_disagreement_score":0.023000369,"about_ca_system_score_codex":0.00008764838,"about_ca_system_score_gemma":0.00092289934,"threshold_uncertainty_score":0.5857579},"labels":[],"label_agreement":null},{"id":"W4404779687","doi":"10.1021/acsbiomedchemau.4c00085","title":"Exploring the Effects of Incorporating Different Bioactive Phospholipids into Messenger Ribonucleic Acid Lipid Nanoparticle (mRNA LNP) Formulations","year":2024,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Michael Smith Health Research BC; NanoMedicines Innovation Network","keywords":"Phospholipid; Chemistry; Biochemistry; HeLa; Messenger RNA; Cell; Membrane; Gene","score_opus":0.019853136033819878,"score_gpt":0.24835114524889235,"score_spread":0.22849800921507246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404779687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972366,0.0010849499,0.00024130962,0.00029121945,0.0007583655,0.000209602,0.0000073735637,0.00003198328,0.00013858266],"genre_scores_gemma":[0.9987899,0.00025204403,0.000082415594,0.00008102113,0.00047739834,0.00011621756,0.000042582204,0.000030132735,0.00012830023],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889493,0.00004758301,0.00027710496,0.00034066214,0.00016518991,0.00027451295],"domain_scores_gemma":[0.9992794,0.00007670553,0.00008749355,0.00039369523,0.000085236315,0.00007747099],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013851772,0.000210676,0.00018564194,0.00005246513,0.00014036447,0.000048253358,0.00025080174,0.00009221806,0.0000073496085],"category_scores_gemma":[0.00013449109,0.00014633908,0.00013390994,0.00020713532,0.00012904676,0.00002824288,0.00020285689,0.00013957427,0.000016872913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037639744,0.000054172717,0.00073829584,0.00011887546,0.00015620224,0.0000029579776,0.0013487986,0.0000067479536,0.98691416,0.00012752018,0.00021425306,0.010280385],"study_design_scores_gemma":[0.00022032758,0.00027542113,0.0022221012,0.00013439593,0.00006802646,0.0000036728045,0.00030816122,0.00017359374,0.9954288,0.0002170563,0.00077028736,0.00017815396],"about_ca_topic_score_codex":0.00006509622,"about_ca_topic_score_gemma":0.00008219751,"teacher_disagreement_score":0.010102231,"about_ca_system_score_codex":0.00005213591,"about_ca_system_score_gemma":0.00008055323,"threshold_uncertainty_score":0.5967534},"labels":[],"label_agreement":null},{"id":"W4407163134","doi":"10.1021/acsbiomedchemau.4c00081","title":"A Reverse Transcription Nucleic-Acid-Based Barcoding System for <i>In Vivo</i> Measurement of Lipid Nanoparticle mRNA Delivery","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University Health Network; University of Toronto; Connaught Fund; Canada Foundation for Innovation; J.P. Bickell Foundation; Canada Research Chairs","keywords":"Nucleic acid; In vivo; Messenger RNA; Reverse transcriptase; Computational biology; Transcription (linguistics); Nanoparticle; microRNA; Chemistry; Cell biology; Biology; RNA; Biochemistry; Nanotechnology; Gene; Biotechnology; Materials science","score_opus":0.018487245543322366,"score_gpt":0.23555867201950367,"score_spread":0.2170714264761813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407163134","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99678373,0.0004608059,0.0014761436,0.00023348621,0.00028344223,0.00031842952,0.000031510892,0.000015091726,0.00039733443],"genre_scores_gemma":[0.999153,0.00004830255,0.00022573897,0.00027146534,0.00007601909,0.000078423436,0.000020725807,0.0000134798975,0.00011283271],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988688,0.000041701147,0.00034518156,0.0003144329,0.00015673069,0.00027312886],"domain_scores_gemma":[0.999367,0.000010236534,0.00008665976,0.00028608437,0.00019912695,0.00005092204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038280356,0.00015284888,0.00020991641,0.00007402873,0.000053907082,0.000012818186,0.00019200577,0.00013685171,0.0000057738444],"category_scores_gemma":[0.000055610715,0.00015344107,0.00013858927,0.00013993273,0.000047338894,0.0000073944925,0.000028405922,0.0000493004,0.0000026331343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003940099,0.00008654313,0.0008407604,0.00028068555,0.000053992822,0.0000012317104,0.00007066705,0.000045394543,0.99590206,0.000028657489,0.0015819973,0.00071397424],"study_design_scores_gemma":[0.0013726032,0.00020266975,0.00010432363,0.0003065289,0.000049348502,8.933845e-7,0.00033060578,0.00024122621,0.9930746,0.000008027075,0.0041656345,0.00014355085],"about_ca_topic_score_codex":0.000061424034,"about_ca_topic_score_gemma":0.00014449249,"teacher_disagreement_score":0.0028274977,"about_ca_system_score_codex":0.00012317327,"about_ca_system_score_gemma":0.000204044,"threshold_uncertainty_score":0.62571454},"labels":[],"label_agreement":null},{"id":"W4408882004","doi":"10.1021/acsbiomedchemau.5c00004","title":"RNA G-Quadruplex Reprogramming with Guanine-Rich Antisense Oligonucleotides Inhibits Monoamine Oxidase B’s Translation","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"Reprogramming; Monoamine oxidase; Oligonucleotide; Chemistry; Translation (biology); Guanine; RNA; Biochemistry; Molecular biology; Biology; DNA; Enzyme; Messenger RNA; Nucleotide; Gene","score_opus":0.011834977913491314,"score_gpt":0.245960819773801,"score_spread":0.23412584186030969,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408882004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909721,0.0010516925,0.0046364185,0.0006641059,0.00010085587,0.00039415402,0.000008790586,0.000059141486,0.0021127122],"genre_scores_gemma":[0.99232596,0.00017186048,0.00569764,0.00024329456,0.00015646966,0.000061527644,0.000117302436,0.000037758764,0.0011881986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99849814,0.00006019852,0.0003045312,0.0005678153,0.0001735948,0.0003956984],"domain_scores_gemma":[0.99909717,0.000028202236,0.00012127928,0.00055110484,0.00010409497,0.00009815241],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028665928,0.00027403212,0.0002423385,0.00008491667,0.00014740611,0.00004973463,0.00020212802,0.00022753769,0.0000144182595],"category_scores_gemma":[0.00010477961,0.00023753002,0.00008398249,0.00029487777,0.00008594749,0.0000104109795,0.000060422684,0.00009781218,0.000010737067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017325311,0.00006807026,0.00040829234,0.000051278257,0.00009680905,0.000011583061,0.000115100214,0.000010527524,0.940105,0.00009778365,0.00016619962,0.05869607],"study_design_scores_gemma":[0.00078240334,0.00020104389,0.0002758342,0.000093530914,0.00006970476,0.000014133451,0.00010458794,0.000028493081,0.98953015,0.00012463846,0.008491579,0.00028388263],"about_ca_topic_score_codex":0.000052819185,"about_ca_topic_score_gemma":0.00008817188,"teacher_disagreement_score":0.058412187,"about_ca_system_score_codex":0.00002618101,"about_ca_system_score_gemma":0.000117159805,"threshold_uncertainty_score":0.96861935},"labels":[],"label_agreement":null},{"id":"W4410209366","doi":"10.1021/acsbiomedchemau.4c00151","title":"A Click Chemistry-Based Biorthogonal Approach for the Detection and Identification of Protein Lysine Malonylation for Osteoarthritis Research","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heritage College","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; National Research Foundation; American Society for Bone and Mineral Research; Arthritis National Research Foundation; Osteopathic Heritage Foundation; Rheumatology Research Foundation; Hevolution Foundation","keywords":"Click chemistry; Biorthogonal system; Lysine; Identification (biology); Chemistry; Computer science; Computational biology; Biochemistry; Combinatorial chemistry; Amino acid; Biology; Artificial intelligence; Botany","score_opus":0.03369553614018001,"score_gpt":0.31982435242443186,"score_spread":0.28612881628425185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410209366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9290334,0.00040504165,0.066263035,0.0014148388,0.0000191426,0.001333036,0.0002799788,0.000060632632,0.0011908676],"genre_scores_gemma":[0.99265426,0.000011713277,0.0007316171,0.0000117995105,0.00015924593,0.003580395,0.00050285575,0.000016651482,0.00233146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987224,0.000012301815,0.00040813364,0.00040292332,0.00020551981,0.00024876563],"domain_scores_gemma":[0.9984966,0.0004183749,0.00018789782,0.00047493266,0.00037545967,0.00004675722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000660194,0.00013642335,0.0001598871,0.000039285256,0.00041366892,0.000049592534,0.00022707958,0.00020631237,0.000015719885],"category_scores_gemma":[0.0004815474,0.00012453813,0.00009282288,0.00037136185,0.00025209034,0.000046230365,0.000044794982,0.00016819427,5.5601004e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016359011,0.00010664843,0.000110583074,0.0010217499,0.000030444247,3.3419465e-8,0.000044917553,0.000016031629,0.9742921,0.00015162262,0.000050048726,0.02401222],"study_design_scores_gemma":[0.0011197764,0.00001573166,0.00014752621,0.00006273829,0.000059939637,0.0000012650296,0.00018712327,0.0061677145,0.98563045,0.0007138384,0.0057866923,0.000107221815],"about_ca_topic_score_codex":0.000020961541,"about_ca_topic_score_gemma":0.000012529367,"teacher_disagreement_score":0.06553142,"about_ca_system_score_codex":0.0000944368,"about_ca_system_score_gemma":0.000145818,"threshold_uncertainty_score":0.5078517},"labels":[],"label_agreement":null},{"id":"W4411011534","doi":"10.1021/acsbiomedchemau.4c00130","title":"Mitochondria-Targeting Biquaternary Ammonium Compounds: Pancreatic Anticancer Activity and Synergistic Interaction with Metformin","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Molecular Sensors and Ion Detection","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Metformin; Mitochondrion; Pharmacology; Chemistry; Ammonium; Medicine; Cancer research; Biochemistry; Diabetes mellitus; Endocrinology","score_opus":0.007155803608073314,"score_gpt":0.2395436226197339,"score_spread":0.23238781901166058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411011534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914716,0.00018966175,0.0018937346,0.00019939459,0.00022117046,0.00009085184,0.0000042789543,0.000091290305,0.005838007],"genre_scores_gemma":[0.997458,0.00008997681,0.00040683054,0.000055770222,0.00013881324,0.000033187785,0.000018497814,0.000022885979,0.0017760403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989417,0.00002777155,0.00020946584,0.00037356646,0.00017933101,0.00026812608],"domain_scores_gemma":[0.9993299,0.000116011455,0.00014632767,0.000269056,0.00006171425,0.000076976714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008820872,0.00021603794,0.00026583963,0.000082354425,0.00015499107,0.00007033981,0.00009946152,0.0001245961,0.000050227427],"category_scores_gemma":[0.000091651564,0.00018149593,0.000048952432,0.00018766291,0.00008648606,0.00014723693,0.00006037671,0.00024767697,0.000006420928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034827294,0.000056349683,0.0020794622,0.00023796053,0.00013898786,0.000020133763,0.00011717072,0.0000086008085,0.99126613,0.00003107845,0.00020391126,0.0054919436],"study_design_scores_gemma":[0.00055952225,0.000037420697,0.0005522131,0.00026128834,0.00014161409,0.000022675726,0.00023403735,0.0016790892,0.99337333,0.000055573353,0.0028790997,0.00020415321],"about_ca_topic_score_codex":0.0007018106,"about_ca_topic_score_gemma":0.00011753842,"teacher_disagreement_score":0.005986387,"about_ca_system_score_codex":0.0001655533,"about_ca_system_score_gemma":0.00006305968,"threshold_uncertainty_score":0.7401189},"labels":[],"label_agreement":null},{"id":"W4412772451","doi":"10.1021/acsbiomedchemau.5c00014","title":"Thermodynamic Coupling between Folding Correctors and the First of Dimerized Nucleotide Binding Domains in CFTR","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; American Heart Association","keywords":"Folding (DSP implementation); Nucleotide; Coupling (piping); Protein folding; Chemistry; Biophysics; Crystallography; Chemical physics; Computational biology; Biology; Materials science; Biochemistry; Engineering","score_opus":0.010723987505104969,"score_gpt":0.2893876764754565,"score_spread":0.27866368897035154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412772451","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965928,0.000594531,0.00020891479,0.001327022,0.00010919989,0.00052046846,0.00000865434,0.00003161246,0.00060676533],"genre_scores_gemma":[0.9992337,0.00014498305,0.00033574144,0.000045296696,0.000047332334,0.000028930872,0.000014256953,0.000019331686,0.00013038641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987148,0.000028579507,0.0003589478,0.00025339398,0.0002818852,0.00036241513],"domain_scores_gemma":[0.9979935,0.001491896,0.000109638495,0.0002868582,0.000044189215,0.000073864205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065585476,0.00015369388,0.0004973637,0.00021371199,0.000120054334,0.000019041836,0.0001821599,0.000072214396,0.00001347703],"category_scores_gemma":[0.0010717829,0.0001047058,0.00006862707,0.00058993907,0.00042969087,0.00006033661,0.0001506807,0.0002620716,0.0000026501903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009256821,0.000059905047,0.41858786,0.0004810608,0.0002546409,0.000015699708,0.0014106047,0.000023746388,0.5730546,0.0003945634,0.000068050904,0.004723558],"study_design_scores_gemma":[0.018116321,0.0001919287,0.44981554,0.0034227758,0.00037615056,0.000010099092,0.0024642441,0.010295331,0.5127151,0.0010719479,0.0011459481,0.00037458143],"about_ca_topic_score_codex":0.00040746556,"about_ca_topic_score_gemma":0.00027168888,"teacher_disagreement_score":0.0603395,"about_ca_system_score_codex":0.00021287968,"about_ca_system_score_gemma":0.00013092002,"threshold_uncertainty_score":0.42697787},"labels":[],"label_agreement":null},{"id":"W4413227043","doi":"10.1021/acsbiomedchemau.5c00126","title":"Transition State Analysis of the Aldol-Like Reaction Catalyzed by NeuB, a Sialic Acid Synthase, Reveals a Stepwise Cationic Mechanism","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cationic polymerization; Aldol reaction; Transition (genetics); Sialic acid; Mechanism (biology); Catalysis; Chemistry; ATP synthase; Stereochemistry; Biochemistry; Organic chemistry; Enzyme; Philosophy; Epistemology","score_opus":0.007049691876435842,"score_gpt":0.2218132589432812,"score_spread":0.21476356706684535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413227043","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960561,0.00017911887,0.0002097782,0.0010588084,0.00010343577,0.00013421192,0.0004124347,0.00007565415,0.0017705075],"genre_scores_gemma":[0.99672604,0.00009441773,0.000013869918,0.00012832199,0.000038024595,0.000095720316,0.00053795584,0.000021488093,0.0023441638],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982062,0.00005893235,0.0005790179,0.00048437362,0.00034691807,0.00032453935],"domain_scores_gemma":[0.99832636,0.00013025096,0.00034897207,0.00096366246,0.00013824484,0.00009249877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029418978,0.00027549916,0.0005085483,0.0001272881,0.00018126823,0.00003707223,0.00038926172,0.00025225952,0.00013484102],"category_scores_gemma":[0.00015114385,0.00024271297,0.00039592135,0.001357761,0.00010888177,0.00011433525,0.000053424323,0.00021634699,0.000004540962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075439966,0.00013469045,0.000049605387,0.00023867283,0.0010277224,0.00000177462,0.00085236947,0.000015958005,0.9966586,0.000029007042,0.0003892618,0.0005268671],"study_design_scores_gemma":[0.00041661612,0.000003581002,0.00007219906,0.00012791404,0.002205601,0.000002078047,0.00040281966,0.0002468328,0.99548227,0.00046578757,0.00036271015,0.0002116025],"about_ca_topic_score_codex":0.00058547815,"about_ca_topic_score_gemma":0.00025094932,"teacher_disagreement_score":0.0012304728,"about_ca_system_score_codex":0.0003682192,"about_ca_system_score_gemma":0.00019824816,"threshold_uncertainty_score":0.9897548},"labels":[],"label_agreement":null},{"id":"W4415167573","doi":"10.1021/acsbiomedchemau.5c00152","title":"Leader-Independent C-Terminal Modification by a Radical <i>S</i> -Adenosyl- <scp>l</scp> -methionine Maturase Enables Macrocyclic GLP-1-Like Peptides","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Aegera Therapeutics (Canada)","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Enzyme; Peptide; Peptide Biosynthesis; Biocatalysis; Sequence (biology); Substrate (aquarium); Cyclic peptide","score_opus":0.008411210718724211,"score_gpt":0.24845905315127062,"score_spread":0.2400478424325464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415167573","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929633,0.0028083296,0.000864524,0.0014314878,0.00010116108,0.00016569211,0.000058381305,0.000043908032,0.0015632054],"genre_scores_gemma":[0.98598176,0.0007386001,0.0003017744,0.00090761547,0.00027255432,0.00006808143,0.00071563205,0.000031175023,0.010982808],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99782467,0.00007277507,0.0004550905,0.000762901,0.00032750526,0.00055707945],"domain_scores_gemma":[0.9988248,0.00011423001,0.00017003715,0.00058389665,0.00008856911,0.00021847308],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025497584,0.0003486524,0.00037941142,0.000079764875,0.00019126892,0.00008803421,0.0005019503,0.0004617185,0.000027060125],"category_scores_gemma":[0.00041573882,0.00031238972,0.00027269113,0.0002859677,0.00023035356,0.000010549183,0.0002004158,0.0002542841,0.000034982317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025923455,0.00019223719,0.0007230692,0.00006364587,0.00018106165,0.000007232421,0.000054971686,0.0000031467132,0.95107716,0.000029322098,0.044391926,0.0032503265],"study_design_scores_gemma":[0.00050308876,0.000033219098,0.00025512237,0.00004493704,0.00016001298,0.000015245966,0.00025135657,0.000047923677,0.86916566,0.00010508384,0.12927121,0.00014712315],"about_ca_topic_score_codex":0.00008865895,"about_ca_topic_score_gemma":0.00003840636,"teacher_disagreement_score":0.08487929,"about_ca_system_score_codex":0.00009519949,"about_ca_system_score_gemma":0.00012386516,"threshold_uncertainty_score":0.9999328},"labels":[],"label_agreement":null},{"id":"W4415397430","doi":"10.1021/acsbiomedchemau.5c00174","title":"Manipulation of 7-Finger Zinc Finger Nuclease Increases the Efficiency of Genome Editing in Human Cells","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"Co-creation place formation support program; Foundation of Kinoshita Memorial Enterprise","keywords":"Zinc finger nuclease; Genome editing; Transcription activator-like effector nuclease; Zinc finger; Genome; Effector","score_opus":0.0070394267222787296,"score_gpt":0.27202335061606137,"score_spread":0.2649839238937826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415397430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973756,0.00055790896,0.0010092591,0.00005342141,0.00008406514,0.0001099116,0.000006370669,0.0000051238994,0.00079834217],"genre_scores_gemma":[0.9995257,0.000030142466,0.00010430426,0.00004239889,0.0001166937,0.000006398829,0.000033245135,0.0000096786935,0.0001314166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993163,0.000019469693,0.00025372402,0.00016834716,0.000084881394,0.00015732952],"domain_scores_gemma":[0.99957395,0.000022420167,0.00008025785,0.00025630265,0.00004439972,0.000022666653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018923564,0.0000972736,0.00012530161,0.00005793256,0.000040365514,0.000005246319,0.0001672223,0.000083268664,0.0000100778825],"category_scores_gemma":[0.00007834347,0.00008355124,0.000053446867,0.00014346033,0.00006077408,0.0000019528225,0.00009713346,0.00005822869,7.0139964e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000087125045,0.000056503064,0.0023407936,0.00006649649,0.000016142727,5.6760035e-7,0.0001303921,0.0009502764,0.9959961,0.000048886755,0.00008135631,0.0003037381],"study_design_scores_gemma":[0.00025069507,0.000037885453,0.01108646,0.00004183627,0.000020242576,5.755493e-7,0.000122051344,0.00015962904,0.98752576,0.000034624467,0.0006450411,0.00007517869],"about_ca_topic_score_codex":0.00017195569,"about_ca_topic_score_gemma":0.00006892087,"teacher_disagreement_score":0.008745667,"about_ca_system_score_codex":0.00001609461,"about_ca_system_score_gemma":0.000038271006,"threshold_uncertainty_score":0.34071207},"labels":[],"label_agreement":null},{"id":"W4417102118","doi":"10.1021/acsbiomedchemau.5c00254","title":"Call for Papers: The Prodigious Diversity of Lipid Nanoparticles for Gene Delivery","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Alberta","funders":"","keywords":"Gene delivery; Gene; Diversity (politics); Identification (biology)","score_opus":0.013820905253396245,"score_gpt":0.2441071880796076,"score_spread":0.23028628282621136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417102118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975071,0.00056580186,0.00031218363,0.00057454815,0.00017632761,0.00041760312,0.00006945998,0.000007886396,0.00036911602],"genre_scores_gemma":[0.9972757,0.00018795616,0.0002148841,0.00058625586,0.00015469817,0.00007685951,0.000073731506,0.000007695516,0.0014222318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928236,0.000014579716,0.00016324608,0.0002468187,0.00006769641,0.00022530305],"domain_scores_gemma":[0.999397,0.000041197818,0.000068024274,0.0002921299,0.00016829402,0.000033386335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014317104,0.00011432241,0.00013354099,0.000020741407,0.0001700075,0.00001100196,0.00031746703,0.0001096724,0.0000022537024],"category_scores_gemma":[0.000103426355,0.00008553306,0.00013860868,0.000058984024,0.00010538817,0.0000033223814,0.00023969421,0.000031748183,0.0000014257062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027435273,0.00005181904,0.0014600224,0.000049441536,0.00013516322,2.2659803e-7,0.00014723289,0.000006824255,0.9851871,0.000036493297,0.008955442,0.0036958402],"study_design_scores_gemma":[0.00056713197,0.00024665118,0.0007061831,0.00001602246,0.00007012096,8.9845565e-7,0.00014438,0.000013383847,0.97859824,0.0001394053,0.01939906,0.00009853731],"about_ca_topic_score_codex":0.000044631066,"about_ca_topic_score_gemma":0.000118266624,"teacher_disagreement_score":0.010443618,"about_ca_system_score_codex":0.00001887697,"about_ca_system_score_gemma":0.000114737115,"threshold_uncertainty_score":0.3487937},"labels":[],"label_agreement":null},{"id":"W7110798330","doi":"10.1021/acsbiomedchemau.5c00224","title":"Is Thiourea the Weak Link? An Investigation of the In Vitro and In Vivo Destabilization of [ <sup>203</sup> Pb]- and [ <sup>212</sup> Pb]Pb <sup>2+</sup> Thiourea-Based Bioconjugates","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Alberta; Simon Fraser University","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Mitacs; Canada Foundation for Innovation","keywords":"Bioconjugation; Biodistribution; In vivo; Thiourea; In vitro; Chelation; Linker; Amide","score_opus":0.026616278602389222,"score_gpt":0.2543478153462283,"score_spread":0.22773153674383909,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7110798330","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98824537,0.0014306679,0.00007031692,0.008449036,0.000037565605,0.0011552818,0.00005615451,0.000040633186,0.00051499624],"genre_scores_gemma":[0.9968737,0.00024233319,0.0009056597,0.0014102488,0.000090515736,0.00008509471,0.000059436352,0.000044476546,0.00028858584],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99689066,0.00054417865,0.0009909229,0.0005965928,0.000523722,0.0004538975],"domain_scores_gemma":[0.99768186,0.00069101166,0.00032083245,0.00089823775,0.000250479,0.00015756524],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015061521,0.00044330157,0.0008313314,0.00036370396,0.00018978794,0.000063983025,0.0004039328,0.00035745878,0.0000610915],"category_scores_gemma":[0.0010038395,0.0002734142,0.000122011894,0.0009781668,0.0008373396,0.00023670803,0.00017639641,0.00044964429,0.0000021617086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064696395,0.0001862271,0.08282969,0.000927129,0.00010131737,0.000001918537,0.01552273,0.00079992827,0.89550775,0.0003104887,0.00031525135,0.0028506129],"study_design_scores_gemma":[0.001719376,0.00022297923,0.00913064,0.0008199686,0.00022145115,0.0000073204164,0.0038616662,0.023214217,0.9583086,0.0015422936,0.0007047106,0.0002468273],"about_ca_topic_score_codex":0.00087944785,"about_ca_topic_score_gemma":0.0002460209,"teacher_disagreement_score":0.07369905,"about_ca_system_score_codex":0.00011845882,"about_ca_system_score_gemma":0.00045811085,"threshold_uncertainty_score":0.9999718},"labels":[],"label_agreement":null}]}