{"meta":{"query_hash":"eb85939ecf01","filters":{"venue":"Alzheimer s Research & Therapy"},"cohort_total":228,"direct_labels_cover":1,"predictions_cover":228,"exported":228,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/eb85939ecf01","api":"https://metacan.xera.ac/api/v1/cohort?venue=Alzheimer+s+Research+%26+Therapy"},"results":[{"id":"W1571275241","doi":"10.1186/s13195-015-0133-2","title":"Unraveling the potential co-contributions of cerebral small vessel vasculopathy to the pathogenesis of Alzheimer’s dementia","year":2015,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; Heart and Stroke Foundation","funders":"","keywords":"Hyperintensity; Dementia; Pathogenesis; Magnetic resonance imaging; Medicine; Disease; White matter; Cognitive decline; Vascular dementia; Cognition; Pathology; Neuroscience; Stroke (engine); Cohort; Alzheimer's disease; Psychology; Cardiology; Radiology","score_opus":0.13083918527559874,"score_gpt":0.3947308470417339,"score_spread":0.26389166176613515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1571275241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.61059123,0.37018076,0.00060282723,0.011087757,0.00025290475,0.0056524836,0.0005378543,0.00007083702,0.0010233582],"genre_scores_gemma":[0.9961423,0.0022767722,0.0004195927,0.0002393749,0.0003200255,0.00038936085,0.00012975698,0.000065185486,0.00001760098],"study_design_codex":"meta_analysis","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99417466,0.0012253821,0.00065688783,0.0005301398,0.0022969681,0.0011159882],"domain_scores_gemma":[0.9948699,0.00035705557,0.00016084689,0.0013993776,0.0023495208,0.00086331146],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0037952682,0.00032325787,0.0005654374,0.00030103963,0.00052437774,0.00006789902,0.0008086219,0.00013886759,0.0001849148],"category_scores_gemma":[0.0003053104,0.00018177656,0.00043404268,0.0011762333,0.0006869657,0.00011659946,0.00027450855,0.0005365107,0.00019033998],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018035525,0.01032418,0.051489804,0.00011254156,0.51546395,0.00054528425,0.010684396,0.0006639199,0.08117025,0.003220461,0.06339829,0.24489142],"study_design_scores_gemma":[0.031752534,0.011987461,0.29037207,0.0004838187,0.021730347,0.00022503096,0.010743102,0.0018429204,0.57275957,0.0038488607,0.052761532,0.0014927398],"about_ca_topic_score_codex":0.0012625004,"about_ca_topic_score_gemma":0.0000359996,"teacher_disagreement_score":0.49373358,"about_ca_system_score_codex":0.000055009772,"about_ca_system_score_gemma":0.0014840551,"threshold_uncertainty_score":0.74126333},"labels":[],"label_agreement":null},{"id":"W1741002350","doi":"10.1186/s13195-015-0140-3","title":"Frailty and the risk of cognitive impairment","year":2015,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Frailty in Older Adults","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Capital District Health Authority; Nova Scotia Health Authority; Dalhousie University","funders":"Canadian Institutes of Health Research; Dalhousie University; Dalhousie Medical Research Foundation","keywords":"Dementia; Cognition; Cognitive impairment; Disease; Population; Cognitive decline; Mechanism (biology); Gerontology; Risk factor; Medicine; Psychology; Psychiatry; Environmental health; Pathology","score_opus":0.2815848604359538,"score_gpt":0.4840241556315442,"score_spread":0.2024392951955904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1741002350","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000076129654,0.99013776,0.0000038251305,0.00052614545,0.0001006681,0.0066871084,0.00018435983,0.000030811465,0.002253171],"genre_scores_gemma":[0.00029512262,0.99761254,0.00007131218,0.00008270364,0.00031332462,0.00072918134,0.00010841488,0.00010016829,0.00068722235],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99348545,0.0028962577,0.00070104044,0.0005836807,0.0016888893,0.0006446886],"domain_scores_gemma":[0.9927499,0.00443712,0.00033190538,0.00097550824,0.0011454647,0.00036009593],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0061430484,0.00045667103,0.0022567268,0.00036459288,0.00016668712,0.00004717356,0.00046219563,0.00034993538,0.00026868004],"category_scores_gemma":[0.00097433996,0.00022922618,0.00053620635,0.0007303686,0.0020850392,0.000063293424,0.0002786038,0.0019830945,0.00016615116],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000828497,0.0002162868,0.000023480688,0.0008381695,0.007136249,0.000022270051,0.00140545,1.504148e-8,1.3761094e-7,0.00005652751,0.008899665,0.98057324],"study_design_scores_gemma":[0.0069150873,0.0013711593,0.000084536776,0.008688077,0.0029990072,0.00009695248,0.0003035538,0.0000061795085,0.000011546706,0.000445972,0.97885966,0.00021823695],"about_ca_topic_score_codex":0.00072096917,"about_ca_topic_score_gemma":0.000017370756,"teacher_disagreement_score":0.980355,"about_ca_system_score_codex":0.00007438919,"about_ca_system_score_gemma":0.001218644,"threshold_uncertainty_score":0.93475723},"labels":[],"label_agreement":null},{"id":"W1963919142","doi":"10.1186/alzrt268","title":"Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels","year":2014,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; National Institute on Aging; National Center for Advancing Translational Sciences; Medical Research Council; University of California, Irvine; University of California, San Francisco; University of California, San Diego; University of California, Davis; University of California, Los Angeles; National Institutes of Health; Rush University; National Institute of Neurological Disorders and Stroke; University of Pittsburgh; University of Washington; Johns Hopkins University; University of Miami; York University; Northwestern University; GHR Foundation; Emory University; Newcastle University; University of Pennsylvania; Vanderbilt University; Institute on Aging, University of Pennsylvania; University of Southern California; Massachusetts General Hospital","keywords":"Haplotype; Disease; Neurology; Tau protein; Association (psychology); Genetic association; Alzheimer's disease; Medicine; Neuroscience; Gene; Genetics; Allele; Psychology; Psychiatry; Biology; Single-nucleotide polymorphism; Internal medicine; Genotype","score_opus":0.0798657361551511,"score_gpt":0.369640704365067,"score_spread":0.2897749682099159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963919142","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8601316,0.12676373,0.00024209946,0.008066188,0.00008067105,0.0031902147,0.0003079509,0.00015849835,0.0010590471],"genre_scores_gemma":[0.99386275,0.0038375491,0.0012299889,0.00020097778,0.00023591045,0.00021382609,0.00010549127,0.00009669949,0.00021678078],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9945209,0.0012263063,0.00038095066,0.0007382853,0.0021692025,0.00096435],"domain_scores_gemma":[0.9959003,0.0010995583,0.00021275946,0.0008718443,0.0007846044,0.0011309779],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020918292,0.00035074755,0.00054645474,0.0004063082,0.00039920732,0.00008259354,0.00025178862,0.00016374871,0.00031342215],"category_scores_gemma":[0.00041982115,0.00024641614,0.0001499354,0.00050834107,0.00041484012,0.00027907017,0.00013904726,0.00058286544,0.000102146536],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019331032,0.0036063665,0.70683384,0.000110552224,0.061221417,0.00027305548,0.0011905791,0.000016900796,0.020149173,0.0004656794,0.022835651,0.16396575],"study_design_scores_gemma":[0.017002653,0.0054087187,0.80675566,0.00042371728,0.0030657277,0.000021391064,0.00021407174,0.00063942245,0.1420773,0.002603602,0.021034725,0.0007530291],"about_ca_topic_score_codex":0.0003398191,"about_ca_topic_score_gemma":0.000020320416,"teacher_disagreement_score":0.16321272,"about_ca_system_score_codex":0.000072677954,"about_ca_system_score_gemma":0.00043947506,"threshold_uncertainty_score":0.9999988},"labels":[],"label_agreement":null},{"id":"W1965064072","doi":"10.1186/s13195-015-0120-7","title":"Cumulative impact of health deficits, social vulnerabilities, and protective factors on cognitive dynamics in late life: a multistate modeling approach","year":2015,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Frailty in Older Adults","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Dalhousie University; Alzheimer Society; Dalhousie Medical Research Foundation","keywords":"Cognition; Neurology; Geriatric psychiatry; Dynamics (music); Cognitive aging; Psychology; Medicine; Gerontology; Neuroscience; Psychiatry","score_opus":0.3151037447786496,"score_gpt":0.4616469733016184,"score_spread":0.1465432285229688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965064072","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99024856,0.00388138,0.0009398584,0.0006369683,0.00002310431,0.0035723962,0.00017385281,0.00003774451,0.0004861394],"genre_scores_gemma":[0.99887156,0.0002923472,0.00030718307,0.00006233838,0.00004172887,0.00018209445,0.00013819922,0.0000632155,0.000041325537],"study_design_codex":"qualitative","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9958274,0.0013883755,0.00051405036,0.00054074137,0.0009749049,0.0007545494],"domain_scores_gemma":[0.9977504,0.00061163673,0.000135552,0.00023292897,0.00088712864,0.00038233039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024812943,0.00029649978,0.0007127453,0.0005064695,0.00017797507,0.000032899025,0.00012839545,0.00016280866,0.000009964005],"category_scores_gemma":[0.00083989406,0.00022866527,0.000113775226,0.00064993475,0.00044693804,0.00017032983,0.00007193253,0.0011684509,0.0000032834885],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.036601786,0.006579967,0.08963485,0.00043124348,0.008615555,0.00005336874,0.5341564,0.025025772,0.0003278632,0.0012484821,0.0004566336,0.2968681],"study_design_scores_gemma":[0.017603239,0.010953522,0.051655278,0.00051731645,0.000058914193,0.0000076823135,0.038252246,0.8760219,0.0003537021,0.00402641,0.000012245457,0.00053752144],"about_ca_topic_score_codex":0.026128192,"about_ca_topic_score_gemma":0.00045335887,"teacher_disagreement_score":0.85099614,"about_ca_system_score_codex":0.00081846304,"about_ca_system_score_gemma":0.0013677386,"threshold_uncertainty_score":0.98035693},"labels":[],"label_agreement":null},{"id":"W2035800748","doi":"10.1186/alzrt201","title":"Pharmacological recommendations for the symptomatic treatment of dementia: the Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012","year":2013,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary; Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Dementia; Medicine; Discontinuation; Memantine; Rivastigmine; Vascular dementia; Disease; Psychiatry; Donepezil; Intensive care medicine; Cognitive decline; Geriatric psychiatry; MEDLINE; Neurology; Internal medicine","score_opus":0.3115003997575944,"score_gpt":0.45035044644432415,"score_spread":0.13885004668672973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035800748","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7598221,0.02797796,0.000017075216,0.19768429,0.000091449365,0.012588129,0.00010634487,0.000014206947,0.001698472],"genre_scores_gemma":[0.96598965,0.026367756,0.00007917843,0.0004682115,0.00006015737,0.0067233783,0.000024551196,0.00001708472,0.00027004478],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99760145,0.0006529242,0.00032879872,0.00026386965,0.00055627,0.00059667113],"domain_scores_gemma":[0.99426395,0.0043469416,0.00008987865,0.00040262064,0.00067012454,0.00022647287],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00089657854,0.00019668073,0.00028212188,0.0001557781,0.0007937515,0.000086473345,0.00023577486,0.000060364455,0.004312533],"category_scores_gemma":[0.00007732622,0.00007988232,0.00014508203,0.00026397026,0.0008567196,0.00004750115,0.000033331613,0.00013582829,0.000035596724],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009138021,0.0044719973,0.06995882,0.000022864773,0.02910869,0.000008588438,0.0038821283,0.0000017657702,0.0049515497,0.0043973154,0.055387244,0.82689524],"study_design_scores_gemma":[0.020447088,0.04572913,0.46271867,0.00020964487,0.0065315566,0.000029513056,0.01138275,0.0034875858,0.14615352,0.003486369,0.29929045,0.00053370977],"about_ca_topic_score_codex":0.025909144,"about_ca_topic_score_gemma":0.0077501815,"teacher_disagreement_score":0.82636154,"about_ca_system_score_codex":0.00009872486,"about_ca_system_score_gemma":0.00044743493,"threshold_uncertainty_score":0.99659765},"labels":[],"label_agreement":null},{"id":"W2074620505","doi":"10.1186/s13195-014-0071-4","title":"Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography","year":2014,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University of Toronto; University Health Network; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Parkinson Society Canada; University of Toronto; Canadian Institutes of Health Research; Teva Pharmaceutical Industries; Ministero dello Sviluppo Economico; Sunnybrook Foundation; Heart and Stroke Foundation of Canada","keywords":"Dementia with Lewy bodies; Corticobasal degeneration; Lewy body; Psychology; Neuropsychology; Dementia; Audiology; Pathology; Medicine; Neuroscience; Cognition; Disease","score_opus":0.06911016650813616,"score_gpt":0.35352579444817855,"score_spread":0.2844156279400424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074620505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99450487,0.0013178313,0.0001942189,0.0023581518,0.000027872733,0.0009793647,0.0000048415677,0.000027443768,0.00058542815],"genre_scores_gemma":[0.9990145,0.00038870794,0.00019643243,0.00021273273,0.00004960515,0.000049543483,0.000022903765,0.000032134965,0.00003343228],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9968505,0.00086622714,0.00028358254,0.00045741795,0.0010680727,0.00047422358],"domain_scores_gemma":[0.9978532,0.0010553232,0.00009629975,0.0003700461,0.000431038,0.00019406009],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012960692,0.00020266518,0.00033518858,0.0004209191,0.00039961,0.00007968137,0.00019494064,0.00007732641,0.0001382008],"category_scores_gemma":[0.00015344244,0.00012090347,0.00005262672,0.0003222835,0.0006130776,0.00008274733,0.00020167645,0.0004435438,0.0000025883744],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011814154,0.00068018807,0.77990204,0.00004563882,0.000999032,0.00001696414,0.0005534458,1.4133701e-7,0.071414486,0.00008580407,0.00019694238,0.14492393],"study_design_scores_gemma":[0.0031307333,0.01030293,0.955727,0.00019766664,0.00017548252,0.000023962742,0.00016790399,0.0005843818,0.029068535,0.00020053393,0.0002968836,0.000124008],"about_ca_topic_score_codex":0.00007177628,"about_ca_topic_score_gemma":0.00001002935,"teacher_disagreement_score":0.17582497,"about_ca_system_score_codex":0.000009410289,"about_ca_system_score_gemma":0.00003566058,"threshold_uncertainty_score":0.49303004},"labels":[],"label_agreement":null},{"id":"W2093832366","doi":"10.1186/alzrt280","title":"Treatment effects in multiple cognitive domains in Alzheimer’s disease: a two-year cohort study","year":2014,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; Sunnybrook Health Science Centre; Heart and Stroke Foundation; McMaster University; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; Alzheimer Society; Scottish Rite Charitable Foundation of Canada","keywords":"Dementia; Cognition; Cohort; Neuropsychology; Medicine; Neurology; Cohort study; Cognitive decline; Alzheimer's disease; Mini–Mental State Examination; Disease; Pediatrics; Psychology; Internal medicine; Psychiatry","score_opus":0.07795308964671971,"score_gpt":0.41486080333842756,"score_spread":0.33690771369170786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093832366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9759234,0.006088534,0.000023759309,0.00060025236,0.00006825948,0.012106931,0.000012343437,0.00006201627,0.005114467],"genre_scores_gemma":[0.99359936,0.0011516687,0.00006270744,0.00019105505,0.00017800754,0.004470123,0.000083931365,0.00007843891,0.00018473281],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9924346,0.002704822,0.00047351015,0.0010456606,0.0019024442,0.0014389337],"domain_scores_gemma":[0.99604017,0.0021293596,0.00005430737,0.00067104516,0.00042705648,0.00067806314],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003060573,0.00041518733,0.0007129587,0.0011094839,0.00021760578,0.00010208329,0.00028370757,0.00009259251,0.0003142235],"category_scores_gemma":[0.00053691794,0.00032677138,0.00017274902,0.0013076003,0.000382711,0.00019221501,0.00015315045,0.0007302745,0.00041912904],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0059005967,0.007943535,0.90293574,0.000011395721,0.0018332198,0.0006746046,0.0011090975,0.0000017562041,0.0003873985,0.00008937707,0.00008903242,0.07902426],"study_design_scores_gemma":[0.037227552,0.0076036337,0.948961,0.000169829,0.00031396034,0.0000055781184,0.0013852554,0.0005708371,0.0021152112,0.0002467616,0.0011105753,0.00028976338],"about_ca_topic_score_codex":0.002308536,"about_ca_topic_score_gemma":0.00091861084,"teacher_disagreement_score":0.078734495,"about_ca_system_score_codex":0.00021718645,"about_ca_system_score_gemma":0.00041850127,"threshold_uncertainty_score":0.99991846},"labels":[],"label_agreement":null},{"id":"W2095613667","doi":"10.1186/alzrt230","title":"Adjusting the compass: new insights into the role of angiogenesis in Alzheimer’s disease","year":2013,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Angiogenesis; Pathogenesis; Neuroscience; Blood–brain barrier; Disease; Cognitive decline; Vascular permeability; Dementia; Pathological; Medicine; Alzheimer's disease; Biology; Pathology; Central nervous system; Cancer research","score_opus":0.19805395110758248,"score_gpt":0.43404299497454496,"score_spread":0.23598904386696248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095613667","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00036137932,0.98885095,0.0000010212497,0.001047585,0.000088785964,0.008724458,0.000031355234,0.000056605862,0.00083788397],"genre_scores_gemma":[0.012417627,0.9838543,0.00008216019,0.00010930015,0.0006172963,0.0023632967,0.0002503751,0.00022431003,0.00008132633],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99022883,0.0028890949,0.0012966389,0.0011184887,0.0028544094,0.0016125467],"domain_scores_gemma":[0.99219835,0.002536629,0.00041117056,0.0026985994,0.0007144809,0.0014407437],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016172121,0.0009501906,0.0022367316,0.0010501591,0.00062957837,0.00018236469,0.0019192222,0.00036662686,0.0005480511],"category_scores_gemma":[0.00024608086,0.00045823544,0.0013424801,0.0028067916,0.0011692822,0.00025198012,0.0006112354,0.0017706875,0.00074800843],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037867483,0.0007349079,0.00041258373,0.00037378242,0.034973804,0.00013985962,0.0009973678,0.0000010361637,0.000003688401,0.00025216135,0.0034999095,0.9582322],"study_design_scores_gemma":[0.0016370363,0.00048153734,0.0008473881,0.004347201,0.007258794,0.000018083561,0.00062093785,0.0000763718,0.0000950971,0.0014765835,0.98264813,0.00049284793],"about_ca_topic_score_codex":0.006389212,"about_ca_topic_score_gemma":0.00013685235,"teacher_disagreement_score":0.9791482,"about_ca_system_score_codex":0.00019010808,"about_ca_system_score_gemma":0.004930124,"threshold_uncertainty_score":0.9997869},"labels":[],"label_agreement":null},{"id":"W2098944887","doi":"10.1186/alzrt202","title":"Knowledge translation: an overview and recommendations in relation to the Fourth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia","year":2013,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Health Policy Implementation Science","field":"Health Professions","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Dalhousie University; Veterans Affairs Canada","funders":"","keywords":"Knowledge translation; Dementia; Action (physics); Health care; USable; Relation (database); Medicine; Population; Psychology; Nursing; Political science; Knowledge management; Computer science; Pathology","score_opus":0.9079562338343575,"score_gpt":0.68182618019079,"score_spread":0.22613005364356753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098944887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5651711,0.0041409684,0.0000079823,0.42378128,0.00007427793,0.0050925803,0.000063642015,0.0000085658785,0.0016596109],"genre_scores_gemma":[0.9822339,0.010955021,0.00026489352,0.0039998507,0.000047226047,0.0024274914,0.00000826594,0.000010595311,0.000052771407],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99526113,0.0033570284,0.00040958545,0.00023268374,0.00024666302,0.00049291167],"domain_scores_gemma":[0.9931503,0.0058043343,0.00007257601,0.00033335836,0.0003173257,0.0003220954],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0028452706,0.0000972489,0.00013633007,0.00025952226,0.0010696625,0.000038527767,0.00016583061,0.00005670449,0.0014544573],"category_scores_gemma":[0.00021979817,0.00005703465,0.000013639845,0.0005866675,0.00016151916,0.00012275267,0.000020634865,0.00023341728,0.00010821855],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048825248,0.00011869295,0.05265687,0.000014336787,0.00012611978,5.233669e-7,0.15969183,0.0000042074553,0.0001112878,0.022091668,0.016878137,0.7482575],"study_design_scores_gemma":[0.0013558916,0.0009795531,0.50725025,0.00012011398,0.000017622617,6.3738383e-7,0.013687477,0.0011261981,0.000095042924,0.0021816192,0.47305155,0.00013405412],"about_ca_topic_score_codex":0.15003385,"about_ca_topic_score_gemma":0.47933817,"teacher_disagreement_score":0.74812347,"about_ca_system_score_codex":0.00009890369,"about_ca_system_score_gemma":0.0008118733,"threshold_uncertainty_score":0.9994584},"labels":[],"label_agreement":null},{"id":"W2102341792","doi":"10.1186/s13195-015-0151-0","title":"New scoring methodology improves the sensitivity of the Alzheimer’s Disease Assessment Scale-Cognitive subscale (ADAS-Cog) in clinical trials","year":2015,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institute on Aging; Medical Center, University of Rochester; Pfizer; University of California, Los Angeles; Yale University; Department of Mechanical Engineering, University of Texas at Austin; National Institutes of Health; Jewish General Hospital; University of California, Davis; Foundation for the National Institutes of Health; University of Southern California; Eisai; Northern California Institute for Research and Education; Genentech; University of South Florida; USF Health Byrd Alzheimer's Institute; McGill University; Dartmouth College; Novartis Pharmaceuticals Corporation; Case Western Reserve University; IXICO; University of Pittsburgh; University of California, San Diego; Johns Hopkins University; Cleveland Clinic; York University; University of Rochester; Alzheimer's Disease Neuroimaging Initiative; Northwestern University; Biogen; BioClinica; F. Hoffmann-La Roche; Rush University; University of Texas at Austin; Wake Forest University; Ohio State University; University of Pennsylvania; Synarc; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Brigham and Women's Hospital; Alzheimer's Association; Servier; University of California, Irvine; Georgetown University; Medpace; Emory University; Meso Scale Diagnostics","keywords":"Clinical trial; Cognition; Medicine; Disease; Internal medicine; Psychiatry","score_opus":0.609961088613493,"score_gpt":0.589740564528101,"score_spread":0.02022052408539199,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102341792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9543124,0.019149505,0.001534949,0.014763327,0.00055408594,0.007472358,0.000033614648,0.000043889504,0.002135907],"genre_scores_gemma":[0.99554545,0.001404977,0.00086864666,0.0007772483,0.000643884,0.00033242535,0.000018064406,0.000056084635,0.00035321817],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9636558,0.030565778,0.0013464363,0.00080910674,0.002506005,0.0011168165],"domain_scores_gemma":[0.9787897,0.017046122,0.00036161742,0.0011338445,0.0016069327,0.0010618113],"candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.082940586,0.00034026118,0.0011499136,0.00035569628,0.00025053276,0.00009434563,0.0005591694,0.00019908202,0.00020943288],"category_scores_gemma":[0.00860093,0.0001841569,0.00063291716,0.0012517466,0.0013734065,0.0002230766,0.0005648703,0.0019376142,0.00004203101],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008392128,0.0013105738,0.41843703,0.000016181031,0.0028168827,0.00009745274,0.0009301139,0.0000017344911,0.011351233,0.00023838795,0.0025700498,0.55383825],"study_design_scores_gemma":[0.008866429,0.0015640062,0.94468105,0.0002159482,0.00092545967,0.00001963725,0.0021950677,0.00036062204,0.03669028,0.0022950175,0.001958485,0.0002279746],"about_ca_topic_score_codex":0.0020094658,"about_ca_topic_score_gemma":0.00031496218,"teacher_disagreement_score":0.55361027,"about_ca_system_score_codex":0.00007270141,"about_ca_system_score_gemma":0.003607266,"threshold_uncertainty_score":0.99975},"labels":[],"label_agreement":null},{"id":"W2107601811","doi":"10.1186/s13195-014-0084-z","title":"Applying a cumulative deficit model of frailty to dementia: progress and future challenges","year":2014,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"National Health and Medical Research Council; National Institute on Aging; National Institutes of Health; Dementia Collaborative Research Centres, Australia","keywords":"Dementia; Vitality; Context (archaeology); Gerontology; Disease; Perspective (graphical); Intervention (counseling); Psychology; Medicine; Psychiatry; Pathology; Computer science","score_opus":0.18812080626115016,"score_gpt":0.42654745583329273,"score_spread":0.23842664957214257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107601811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8963214,0.07399028,0.0009707877,0.011698753,0.000048814556,0.0053618937,0.000012009985,0.0000665311,0.011529492],"genre_scores_gemma":[0.9883623,0.007737004,0.0021341683,0.00026213954,0.0002283737,0.0011063521,0.000009239368,0.000041168943,0.0001192615],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.996808,0.00035615134,0.0002656974,0.0005024742,0.0013665045,0.00070120755],"domain_scores_gemma":[0.99819404,0.00019227745,0.000048118512,0.00040510847,0.00079258217,0.0003678817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001963867,0.00019770655,0.00036077475,0.0004096711,0.00019375875,0.00004458804,0.00021185739,0.000107972824,0.00013594335],"category_scores_gemma":[0.000054781238,0.0001529271,0.00008028987,0.00039290244,0.00030238446,0.00012295115,0.00019427952,0.00043235577,0.000028714767],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011433795,0.0005173172,0.013928268,0.000080787686,0.0014813046,0.0000053127733,0.0019592154,0.000005642695,0.008396961,0.0034583209,0.00034096185,0.9686825],"study_design_scores_gemma":[0.025949877,0.024983648,0.3765629,0.00095340057,0.001082139,0.000054601293,0.012670581,0.04358231,0.14389762,0.016879594,0.35155293,0.0018303924],"about_ca_topic_score_codex":0.000030005627,"about_ca_topic_score_gemma":0.000010148091,"teacher_disagreement_score":0.9668521,"about_ca_system_score_codex":0.000017740827,"about_ca_system_score_gemma":0.00012343653,"threshold_uncertainty_score":0.6236186},"labels":[],"label_agreement":null},{"id":"W2112404965","doi":"10.1186/alzrt266","title":"Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment","year":2014,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; Medical Center, University of Rochester; National Institute on Aging; University of California, San Francisco; Canadian Institutes of Health Research; Pfizer; University of California, Los Angeles; National Institutes of Health; Jewish General Hospital; University of California, Davis; Foundation for the National Institutes of Health; University of Southern California; Eisai; Northern California Institute for Research and Education; Genentech; University of South Florida; USF Health Byrd Alzheimer's Institute; McGill University; Dartmouth College; Novartis Pharmaceuticals Corporation; Case Western Reserve University; IXICO; University of Pittsburgh; University of California, San Diego; Johns Hopkins University; Cleveland Clinic; York University; University of Rochester; Northwestern University; Biogen; BioClinica; Meso Scale Diagnostics; Rush University; F. Hoffmann-La Roche; University of Pennsylvania; Wake Forest University; Ohio State University; Synarc; Yale University; Bristol-Myers Squibb; Medpace; Emory University; Alzheimer's Association; Brigham and Women's Hospital; Eli Lilly and Company; University of California, Irvine; Georgetown University; Servier","keywords":"Neurology; Geriatric psychiatry; Cerebrospinal fluid; Cognitive impairment; Cognition; Medicine; Complement (music); Cognitive decline; Factor H; Internal medicine; Clinical psychology; Psychology; Dementia; Psychiatry; Complement system; Immunology; Disease; Chemistry; Antibody","score_opus":0.20080547924110667,"score_gpt":0.3985728069917373,"score_spread":0.19776732775063063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112404965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99588645,0.00015032377,0.0010755918,0.0008058405,0.000099548226,0.001524843,0.00020063264,0.00003406013,0.00022273594],"genre_scores_gemma":[0.99773645,0.00038521938,0.00007503195,0.0015010595,0.00007814752,0.00011192567,0.000009768882,0.000031987165,0.00007041118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960597,0.001312291,0.00047857713,0.0006121429,0.0010283039,0.00050898734],"domain_scores_gemma":[0.99810797,0.0010921458,0.000112718546,0.00021789949,0.00028135136,0.00018793695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008783865,0.00021667601,0.00027413186,0.0003498413,0.00019647456,0.000089572,0.00024663762,0.000058993646,0.0006696312],"category_scores_gemma":[0.00028945922,0.00018801514,0.000057033787,0.0004028135,0.00031544015,0.00022331833,0.00018351535,0.00033377833,0.00005490982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010234015,0.0004407856,0.0015833945,0.000016935459,0.000039866016,0.000010404914,0.001120618,0.000005556667,0.9661904,0.0009213519,0.00008192084,0.028565394],"study_design_scores_gemma":[0.003913993,0.0019126601,0.0452552,0.000077078825,0.000007466228,0.0000060283946,0.000121447556,0.0018602782,0.9459411,0.0003522577,0.00038892674,0.00016356856],"about_ca_topic_score_codex":0.000021832822,"about_ca_topic_score_gemma":0.000032212327,"teacher_disagreement_score":0.0436718,"about_ca_system_score_codex":0.000015709302,"about_ca_system_score_gemma":0.000080955426,"threshold_uncertainty_score":0.7667035},"labels":[],"label_agreement":null},{"id":"W2114606300","doi":"10.1186/s13195-014-0056-3","title":"Association between cell-bound blood amyloid-β(1 - 40) levels and hippocampus volume","year":2014,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; University of California, Los Angeles; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; Servier; Eisai; Northern California Institute for Research and Education; University of California, San Diego; Pfizer; Biogen; BioClinica; Medpace; Eli Lilly and Company; Bristol-Myers Squibb; F. Hoffmann-La Roche; Alzheimer's Drug Discovery Foundation; Synarc; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; National Institute on Aging; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Hippocampus; Amyloid (mycology); Neuroscience; Internal medicine; Medicine; Biology; Pathology","score_opus":0.07457507970321342,"score_gpt":0.3725420184600937,"score_spread":0.2979669387568803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114606300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97804904,0.005275403,0.000095415104,0.0044746604,0.00006426962,0.0011676543,0.000016100677,0.00007131749,0.0107861115],"genre_scores_gemma":[0.9883272,0.0012576946,0.00018002893,0.00042975802,0.00058083516,0.00012263974,0.00004732217,0.000055847133,0.008998663],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9951073,0.0009516814,0.0003215647,0.00057234766,0.0019386197,0.0011084754],"domain_scores_gemma":[0.9973793,0.0008096384,0.0000852401,0.0004343907,0.00079899305,0.0004924187],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004614904,0.00023129473,0.00039831825,0.00038816285,0.0004382079,0.00024261534,0.0002454346,0.00020818003,0.0012528801],"category_scores_gemma":[0.00029772057,0.00019846555,0.00011131293,0.00054105424,0.0002575676,0.00021770611,0.00014810155,0.0008519764,0.00047450923],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002720367,0.000484759,0.7726949,0.000034787958,0.0023274766,0.000017151091,0.00044187144,8.072411e-8,0.021943355,0.000042432664,0.0073544597,0.19438672],"study_design_scores_gemma":[0.005873522,0.0029903396,0.85582703,0.000048867685,0.000429767,0.000009509273,0.00015459521,0.00006662498,0.050065275,0.0026363095,0.08162673,0.00027140835],"about_ca_topic_score_codex":0.00023627303,"about_ca_topic_score_gemma":0.000010930176,"teacher_disagreement_score":0.19411531,"about_ca_system_score_codex":0.000079980266,"about_ca_system_score_gemma":0.00022460679,"threshold_uncertainty_score":0.99966013},"labels":[],"label_agreement":null},{"id":"W2118021228","doi":"10.1186/alzrt171","title":"Modeling Alzheimer's disease with non-transgenic rat models","year":2013,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital; McGill University Health Centre; Royal Victoria Regional Health Centre","funders":"McGill University Health Centre","keywords":"Disease; Drug development; Dementia; Animal model; Clinical phenotype; Transgene; Neuroscience; Alzheimer's disease; Clinical trial; Drug; Medicine; Biology; Bioinformatics; Phenotype; Genetics; Pathology; Pharmacology; Gene","score_opus":0.3607512252987541,"score_gpt":0.46256856531526525,"score_spread":0.10181734001651116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118021228","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000006324114,0.7021632,0.29361707,0.00022768471,0.00025014175,0.003215768,0.000017953038,0.00016593009,0.00033591592],"genre_scores_gemma":[0.00024218668,0.96119004,0.035625603,0.0001212995,0.00036210148,0.002049303,0.00008866591,0.0002323114,0.00008850197],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9888633,0.0030007747,0.0010466243,0.0022333406,0.0031028823,0.0017530713],"domain_scores_gemma":[0.9930532,0.001551844,0.00022049726,0.003093905,0.0010270433,0.0010535063],"candidate_categories":["metaepi_narrow","scholarly_communication","open_science"],"consensus_categories":[],"category_scores_codex":[0.0030696609,0.0011377361,0.0019178655,0.001173176,0.0006097501,0.001335715,0.0056343144,0.0003345767,0.00009435108],"category_scores_gemma":[0.000031696873,0.00081689697,0.0008784507,0.0026738641,0.00033708874,0.0022583576,0.00087324483,0.0019646129,0.00058043486],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042792944,0.0001685917,1.2314403e-7,0.00029793024,0.0022044852,0.000048800484,0.00024053195,0.055666443,4.7502175e-7,0.0044258004,0.000555821,0.9363482],"study_design_scores_gemma":[0.00053429446,0.00021132169,3.4242822e-7,0.00217871,0.00056908344,0.000022387781,0.000010225778,0.7159704,0.0000071083023,0.012691257,0.26671183,0.0010930637],"about_ca_topic_score_codex":0.00024664693,"about_ca_topic_score_gemma":0.0000075483845,"teacher_disagreement_score":0.93525517,"about_ca_system_score_codex":0.00013641731,"about_ca_system_score_gemma":0.0041078334,"threshold_uncertainty_score":0.99974567},"labels":[],"label_agreement":null},{"id":"W2122339962","doi":"10.1186/alzrt223","title":"Fluid biomarkers for diagnosing dementia: rationale and the Canadian Consensus on Diagnosis and Treatment of Dementia recommendations for Canadian physicians","year":2013,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Centre for Addiction and Mental Health; Sunnybrook Health Science Centre; University of British Columbia Hospital; University of British Columbia; McGill University; Douglas Mental Health University Institute","funders":"University of Toronto; Parkinson Society Canada; Ministero dello Sviluppo Economico; Sunnybrook Foundation; McGill University; Canadian Institutes of Health Research; Teva Pharmaceutical Industries; Alzheimer's Association","keywords":"Dementia; Medicine; Intensive care medicine; Consensus conference; Clinical Practice; Clinical trial; MEDLINE; Pathology; Medical physics; Family medicine; Disease; Internal medicine; Political science","score_opus":0.14370309034799528,"score_gpt":0.3876831306821456,"score_spread":0.24398004033415033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122339962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.47508302,0.21345511,0.000016623037,0.27431852,0.0001756489,0.033638194,0.0022108534,0.00003387827,0.0010681504],"genre_scores_gemma":[0.977913,0.011159783,0.0007416726,0.00070654665,0.00008883152,0.008941772,0.00038257218,0.000038886672,0.000026904027],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99812657,0.00022401348,0.00024267996,0.00035699588,0.00032713026,0.0007226085],"domain_scores_gemma":[0.9962055,0.0022237913,0.00005211334,0.0003013206,0.0005584518,0.000658792],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048752737,0.00019367678,0.00029010256,0.00040296582,0.0011843138,0.00012255635,0.000091285285,0.000072299765,0.00014804568],"category_scores_gemma":[0.00013367759,0.00013354754,0.0001233352,0.00022243314,0.0005990868,0.000078885816,0.000013383989,0.00008099087,0.000010318341],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032491789,0.0017141677,0.057310842,0.000053393742,0.13752817,0.000024196052,0.002633353,0.0000031854133,0.00030162453,0.0047639343,0.18220505,0.6102129],"study_design_scores_gemma":[0.10782242,0.020601848,0.20884445,0.0006517437,0.010792216,0.000037377173,0.0065714912,0.005689881,0.02987641,0.012663972,0.5949591,0.0014890882],"about_ca_topic_score_codex":0.59713787,"about_ca_topic_score_gemma":0.51487917,"teacher_disagreement_score":0.6087238,"about_ca_system_score_codex":0.00018607975,"about_ca_system_score_gemma":0.0011030608,"threshold_uncertainty_score":0.91089034},"labels":[],"label_agreement":null},{"id":"W2123826558","doi":"10.1186/alzrt55","title":"Prevention of Alzheimer's disease in high risk groups: statin therapy in subjects with PSEN1 mutations or heterozygosity for apolipoprotein E epsilon 4","year":2010,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; Occupational Cancer Research Centre; University of Toronto","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"PSEN1; Medicine; Statin; Internal medicine; Presenilin; Biomarker; Oncology; Alzheimer's disease; Disease; Familial hypercholesterolemia; Neurodegeneration; Cholesterol; Biology; Genetics","score_opus":0.08576641156377696,"score_gpt":0.39998502163315686,"score_spread":0.3142186100693799,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123826558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97661114,0.0136702275,0.00005896009,0.00068242557,0.00005882684,0.008551486,0.00026121005,0.000052806077,0.000052932483],"genre_scores_gemma":[0.99016386,0.003190766,0.0029415262,0.000050017825,0.00010243491,0.0030108949,0.00039784785,0.00011212194,0.00003051307],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9949006,0.0008747638,0.00067755004,0.0008549678,0.0014703232,0.001221787],"domain_scores_gemma":[0.9966333,0.0007148901,0.0002233807,0.0009835464,0.0006810398,0.0007638594],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016932235,0.0004271028,0.00070275884,0.0010413057,0.00026772427,0.000069527516,0.00034878805,0.0001871393,0.00030909944],"category_scores_gemma":[0.0002559767,0.00030056576,0.00022090532,0.0013888109,0.0006189432,0.00041199324,0.00006628331,0.0010613011,0.000025873775],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.12307898,0.0185633,0.58616245,0.00017053625,0.024785345,0.00084074674,0.002721797,0.00009613645,0.008013963,0.00086162856,0.00039711597,0.234308],"study_design_scores_gemma":[0.0362994,0.012736611,0.892296,0.00036233454,0.00063359574,0.000014746518,0.00040663578,0.0008458645,0.047347274,0.0082007125,0.0002688191,0.0005879951],"about_ca_topic_score_codex":0.008108944,"about_ca_topic_score_gemma":0.004718677,"teacher_disagreement_score":0.30613357,"about_ca_system_score_codex":0.00008122882,"about_ca_system_score_gemma":0.0012059059,"threshold_uncertainty_score":0.9999446},"labels":[],"label_agreement":null},{"id":"W2126020723","doi":"10.1186/s13195-015-0125-2","title":"The dynamics of monocytes and microglia in Alzheimer’s disease","year":2015,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":238,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Microglia; Neurology; Geriatric psychiatry; Medicine; Disease; Neuroscience; Psychiatry; Immunology; Psychology; Pathology; Inflammation","score_opus":0.2531138378180424,"score_gpt":0.39593242825686437,"score_spread":0.14281859043882195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126020723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97459644,0.013650943,0.000063564534,0.009505719,0.00026767838,0.0011461929,0.000022469012,0.000059482765,0.00068749575],"genre_scores_gemma":[0.9946031,0.0046177995,0.00007258589,0.00038325458,0.000040910887,0.00006732995,0.000002811709,0.000027551947,0.00018465998],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973553,0.0008989585,0.00029474535,0.00037596576,0.0006926533,0.00038240312],"domain_scores_gemma":[0.9983665,0.00068778545,0.00006994648,0.00044903546,0.00015980192,0.00026693704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011660588,0.00013190655,0.00013324867,0.0001927667,0.00023925168,0.00013752392,0.0004313757,0.00003831664,0.000016928825],"category_scores_gemma":[0.00044912304,0.00009507195,0.000037561244,0.0005017023,0.00039914303,0.00020450728,0.00012772625,0.00028308723,0.000033557357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016109116,0.00029933144,0.0012553183,0.0000049485725,0.000059518647,0.00008842644,0.0013393555,0.0001290725,0.70974535,0.14489886,0.0026887965,0.1378801],"study_design_scores_gemma":[0.0011266049,0.00024048565,0.0007826929,0.000007874675,0.000010164786,0.0000068768522,0.0001776177,0.015497309,0.96209484,0.010333767,0.009567149,0.00015461513],"about_ca_topic_score_codex":0.000039911058,"about_ca_topic_score_gemma":0.000065840955,"teacher_disagreement_score":0.25234947,"about_ca_system_score_codex":0.000017059947,"about_ca_system_score_gemma":0.00017762066,"threshold_uncertainty_score":0.38769215},"labels":[],"label_agreement":null},{"id":"W2128157173","doi":"10.1186/alzrt196","title":"Diagnosis and Treatment of Dementia: the Fourth Canadian Consensus Conference","year":2013,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Clinical practice guidelines implementation","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University; Hamilton Health Sciences","funders":"","keywords":"Intensive care medicine; Dementia; Medicine; Disease; Adverse effect; Clinical trial; Value (mathematics); Computer science; Pathology","score_opus":0.5875906868360923,"score_gpt":0.5312723405431917,"score_spread":0.056318346292900556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128157173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88223183,0.011398665,0.0000069421285,0.10311998,0.00005618481,0.002325819,0.000016284013,0.000010517199,0.00083377096],"genre_scores_gemma":[0.9834117,0.014560729,0.0005567099,0.00089302054,0.00008867582,0.00038814513,0.000015484808,0.000014953947,0.000070527065],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9982917,0.00034832963,0.0003835935,0.0002096929,0.00040402758,0.00036270163],"domain_scores_gemma":[0.99595034,0.0026060247,0.000073412,0.00037702004,0.0006928589,0.0003003486],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00087238324,0.00010366857,0.0001961635,0.00012338681,0.00016761634,0.00004899586,0.00009699601,0.00005277514,0.0020947193],"category_scores_gemma":[0.00052819663,0.000062180174,0.00004930569,0.00019356226,0.00035949392,0.00006522415,0.00002359916,0.00016066877,0.000080468875],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001629025,0.00025280777,0.0743513,0.0000037439627,0.0017675535,0.00001485558,0.0010156691,5.8558504e-7,0.0011512131,0.00028049335,0.019376034,0.90162283],"study_design_scores_gemma":[0.008576509,0.0059363157,0.51313347,0.000060878956,0.0007458887,0.00005461994,0.006297707,0.0009973701,0.013288698,0.0022263103,0.44839528,0.00028693688],"about_ca_topic_score_codex":0.372447,"about_ca_topic_score_gemma":0.071455166,"teacher_disagreement_score":0.9013359,"about_ca_system_score_codex":0.000045900822,"about_ca_system_score_gemma":0.0005929432,"threshold_uncertainty_score":0.9988175},"labels":[],"label_agreement":null},{"id":"W2129836373","doi":"10.1186/alzrt135","title":"Apolipoprotein E, amyloid-ß clearance and therapeutic opportunities in Alzheimer's disease","year":2012,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eisai Canada; Eisai","keywords":"Apolipoprotein E; Disease; Medicine; Alzheimer's disease; Neuroscience; Amyloid (mycology); Neurodegeneration; Dementia; Bioinformatics; Psychology; Biology; Pathology","score_opus":0.39420625891680683,"score_gpt":0.45953366259520556,"score_spread":0.06532740367839873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129836373","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021458593,0.98987466,6.1551214e-7,0.0006215343,0.00011459016,0.007671924,0.00020439507,0.00012682151,0.0011708761],"genre_scores_gemma":[0.011414324,0.9835062,0.000055187804,0.00022783228,0.00062777806,0.0032094158,0.0004094336,0.00036637936,0.00018343801],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9901386,0.0022711956,0.0010823084,0.0014168068,0.002385153,0.002705943],"domain_scores_gemma":[0.9939009,0.0007430215,0.00025058578,0.0018381074,0.0004051298,0.002862287],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0022491934,0.0012209505,0.0027206314,0.001752179,0.0004501044,0.0002283199,0.000732481,0.0005746759,0.0006708047],"category_scores_gemma":[0.000060195915,0.00091410085,0.0007528301,0.0013173019,0.0014015252,0.00034751903,0.00037856857,0.0023698728,0.0006226313],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011309983,0.0012690489,0.00030973813,0.0013567673,0.027696371,0.0009243123,0.00015595318,5.6219434e-8,4.284501e-7,0.0004152836,0.0003573847,0.96638364],"study_design_scores_gemma":[0.0026030068,0.0007243958,0.0014759143,0.0054123634,0.006596538,0.00011299803,0.00013042487,0.00001029649,0.000009660221,0.00052269537,0.9814967,0.00090499176],"about_ca_topic_score_codex":0.0006890727,"about_ca_topic_score_gemma":0.000026773403,"teacher_disagreement_score":0.9811393,"about_ca_system_score_codex":0.00021821854,"about_ca_system_score_gemma":0.0028266448,"threshold_uncertainty_score":0.9999317},"labels":[],"label_agreement":null},{"id":"W2131169418","doi":"10.1186/s13195-015-0152-z","title":"Predicting Alzheimer's disease development: a comparison of cognitive criteria and associated neuroimaging biomarkers","year":2015,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut Universitaire en Santé Mentale de Québec; Université Laval; Heart and Stroke Foundation; Sunnybrook Health Science Centre","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Genentech; National Institutes of Health; Linda C. Campbell Foundation; Eisai; University of California, San Diego; University of Toronto; H. Lundbeck A/S; Northern California Institute for Research and Education; Canadian Vascular Network; Servier; Pfizer; Biogen; Sunnybrook Research Institute; BioClinica; F. Hoffmann-La Roche; University of Southern California; Novartis Pharmaceuticals Corporation; Heart and Stroke Foundation of Canada; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; IXICO; Fonds de Recherche du Québec - Santé; L'Oreal USA; Alzheimer's Association; Foundation for the National Institutes of Health; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics","keywords":"Geriatric psychiatry; Neuroimaging; Neurology; Disease; Cognition; Cognitive aging; Medicine; Dementia; Psychology; Psychiatry; Pathology","score_opus":0.2039341602275118,"score_gpt":0.4546558526369192,"score_spread":0.25072169240940745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131169418","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96575147,0.028573658,0.00003927,0.0008954248,0.000074049814,0.001595578,0.000024245355,0.00007412696,0.0029722054],"genre_scores_gemma":[0.99880236,0.0003438861,0.00019711076,0.0001709683,0.00006606433,0.00015436012,0.00013227903,0.00005371189,0.00007923366],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99541146,0.00086729217,0.0005049105,0.00055847823,0.0017953895,0.00086247653],"domain_scores_gemma":[0.99625105,0.0006975607,0.00012510276,0.0002526841,0.001704723,0.00096890633],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028541507,0.00025316095,0.0004611902,0.000553301,0.000286363,0.00011572467,0.00019763212,0.00007884301,0.00017757458],"category_scores_gemma":[0.0011675494,0.00022282866,0.00008255704,0.0007960849,0.0006568905,0.0002625162,0.00024755398,0.00052327744,0.000031471125],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034789378,0.0011419837,0.86380255,0.000021442822,0.003369273,0.000078187695,0.00403755,1.3695794e-7,0.002377732,0.000009105526,0.0014703372,0.12021274],"study_design_scores_gemma":[0.008388365,0.001794604,0.9538238,0.00055121374,0.0005131042,0.000012124355,0.0049182996,0.0021032698,0.025056282,0.00014446523,0.002387468,0.00030699815],"about_ca_topic_score_codex":0.00016478855,"about_ca_topic_score_gemma":0.000010628122,"teacher_disagreement_score":0.11990574,"about_ca_system_score_codex":0.000047649344,"about_ca_system_score_gemma":0.0008830946,"threshold_uncertainty_score":0.90866894},"labels":[],"label_agreement":null},{"id":"W2134776511","doi":"10.1186/alzrt40","title":"Con: Can biomarkers be gold standards in Alzheimer's disease?","year":2010,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Capital District Health Authority; Dalhousie University","funders":"Dalhousie University; Atlantic Canada Opportunities Agency; Alzheimer Society; Dalhousie Medical Research Foundation","keywords":"Dementia; Gold standard (test); Disease; Biomarker; Certainty; Medicine; Construct (python library); Intensive care medicine; Psychology; Psychiatry; Pathology; Computer science; Internal medicine","score_opus":0.08569054226500868,"score_gpt":0.4220847933467511,"score_spread":0.3363942510817424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134776511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9358617,0.016720261,0.0000057151306,0.024696853,0.00029400524,0.0031334462,0.00018498638,0.0001082347,0.018994762],"genre_scores_gemma":[0.9948778,0.0023593602,0.00012180959,0.0011855189,0.00027609107,0.00046042606,0.0001140621,0.00008190412,0.0005229944],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99348307,0.0005621998,0.00042149937,0.0007737512,0.0032443071,0.0015152046],"domain_scores_gemma":[0.99633795,0.00037960403,0.000050242743,0.0008957496,0.0012350702,0.0011013952],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0043982505,0.00032483353,0.000421046,0.00089194195,0.00022300112,0.00017261926,0.0005052352,0.0001730377,0.0042042253],"category_scores_gemma":[0.00034010064,0.00026817698,0.00018148302,0.0012906238,0.0009795269,0.0002054175,0.00018889805,0.0016027052,0.000103904],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008366742,0.00200309,0.48921695,0.000032113003,0.004527849,0.001091181,0.0008519651,3.2686745e-7,0.042463664,0.0010793322,0.049993113,0.40037367],"study_design_scores_gemma":[0.009584912,0.0018509352,0.5780503,0.00011891736,0.00024856636,0.000033456254,0.0007187835,0.00012138313,0.03660093,0.0009987478,0.37112832,0.0005447439],"about_ca_topic_score_codex":0.0009200064,"about_ca_topic_score_gemma":0.0006630244,"teacher_disagreement_score":0.3998289,"about_ca_system_score_codex":0.00009332353,"about_ca_system_score_gemma":0.001962572,"threshold_uncertainty_score":0.99997705},"labels":[],"label_agreement":null},{"id":"W2137527705","doi":"10.1186/alzrt90","title":"Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies","year":2011,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":135,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"National Institute on Aging; Alzheimer's Drug Discovery Foundation","keywords":"Medicine; Disease; Clinical trial; Translational research; Animal testing; Clinical study design; Regulatory science; Preclinical research; Animal model; Drug development; Drug discovery; Bioinformatics; Drug; Pathology; Pharmacology; Medical physics; Biology; Internal medicine","score_opus":0.7225265207262156,"score_gpt":0.5655746762514848,"score_spread":0.15695184447473076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137527705","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16614579,0.43151885,0.3419687,0.031333946,0.0041080858,0.020451954,0.0003632709,0.00087851373,0.0032308847],"genre_scores_gemma":[0.5314866,0.0033702492,0.4573472,0.00085544056,0.0015502964,0.004556247,0.000043713142,0.00014188734,0.0006483922],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99457157,0.0013023067,0.0006828084,0.0012793181,0.0011202008,0.0010437742],"domain_scores_gemma":[0.9834463,0.0133542465,0.0004451964,0.001038649,0.0013762474,0.00033938725],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006789179,0.00036117446,0.0004787456,0.00027626075,0.0009060805,0.0007883542,0.0022140634,0.000085141204,0.00001881845],"category_scores_gemma":[0.0026741738,0.00030285903,0.00034550292,0.00063864375,0.00042083138,0.0036875869,0.0007701725,0.0004513229,0.00002930495],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0066881008,0.0029806916,0.0016303664,0.00011438571,0.008574781,0.000041145842,0.01364887,0.0003839362,0.0010800768,0.21001156,0.019962164,0.7348839],"study_design_scores_gemma":[0.011339367,0.009843559,0.015908604,0.0005125252,0.0012848403,0.000030122199,0.005150658,0.2222297,0.05694077,0.41377264,0.25909653,0.0038906597],"about_ca_topic_score_codex":0.00015442318,"about_ca_topic_score_gemma":0.000033650904,"teacher_disagreement_score":0.7309933,"about_ca_system_score_codex":0.000046978177,"about_ca_system_score_gemma":0.0008167623,"threshold_uncertainty_score":0.99994236},"labels":[],"label_agreement":null},{"id":"W2139018071","doi":"10.1186/alzrt211","title":"The role of APP and BACE1 trafficking in APP processing and amyloid-β generation","year":2013,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":206,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Amyloid precursor protein; Senile plaques; Amyloid precursor protein secretase; Alpha secretase; P3 peptide; Cell biology; Biochemistry of Alzheimer's disease; BACE1-AS; Extracellular; Amyloid (mycology); Cleavage (geology); Alzheimer's disease; Chemistry; Neuroscience; Biology; Disease; Medicine; Pathology","score_opus":0.16548635957504557,"score_gpt":0.43337304368786084,"score_spread":0.26788668411281524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139018071","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0019911004,0.9936499,0.0000011229738,0.00012301629,0.000019009645,0.0037567161,0.000011971402,0.000026367918,0.00042081784],"genre_scores_gemma":[0.012567483,0.9859646,0.00010847483,0.0000136836625,0.00020091058,0.0009248751,0.000082420935,0.00008631812,0.000051226943],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961428,0.00077994954,0.00058815593,0.0006338839,0.0010426723,0.00081253436],"domain_scores_gemma":[0.99804443,0.00053867564,0.00016821502,0.00051047467,0.00033875628,0.00039946224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014896721,0.0004024666,0.0010880982,0.0004851499,0.0004060549,0.00022863763,0.00025045988,0.00026437597,0.00003920253],"category_scores_gemma":[0.000073787465,0.00023528772,0.00016138348,0.00068724516,0.00064977177,0.00019220734,0.00013996649,0.00088035635,0.000025850282],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009717606,0.00020448458,0.00014154697,0.0007046803,0.0045255776,0.000020768714,0.00024948842,9.1603575e-8,0.000030019544,0.00005080013,0.00019113226,0.99378425],"study_design_scores_gemma":[0.0024542338,0.0009128958,0.00027540626,0.005136843,0.0012950484,0.00009247721,0.00053963455,0.00067647017,0.00027616386,0.00025831044,0.98763114,0.00045138918],"about_ca_topic_score_codex":0.00022634624,"about_ca_topic_score_gemma":0.00003278287,"teacher_disagreement_score":0.99333286,"about_ca_system_score_codex":0.0000702462,"about_ca_system_score_gemma":0.0009594432,"threshold_uncertainty_score":0.95947546},"labels":[],"label_agreement":null},{"id":"W2139748910","doi":"10.1186/alzrt279","title":"Subcortical hyperintensity volumetrics in Alzheimer’s disease and normal elderly in the Sunnybrook Dementia Study: correlations with atrophy, executive function, mental processing speed, and verbal memory","year":2014,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; Ontario Brain Institute; Baycrest Hospital; Heart and Stroke Foundation","funders":"University of Toronto; Canadian Institutes of Health Research; Sunnybrook Research Institute; Alzheimer Society; Heart and Stroke Foundation of Canada","keywords":"Atrophy; Hyperintensity; Dementia; Brain size; Psychology; Magnetic resonance imaging; Medicine; Cardiology; Alzheimer's disease; White matter; Internal medicine; Pathology; Pathological; Audiology; Disease; Radiology","score_opus":0.05905077940763388,"score_gpt":0.3464990311664525,"score_spread":0.2874482517588186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139748910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9840694,0.011538561,0.0001636895,0.0009424101,0.000035529418,0.002564247,0.0000041377575,0.000019562955,0.00066245976],"genre_scores_gemma":[0.99875426,0.0005747508,0.000057640435,0.00026741822,0.000083113155,0.00015985181,0.000023239667,0.00002820261,0.000051496794],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99633175,0.00077883055,0.0003064428,0.0005576224,0.0013338698,0.0006914867],"domain_scores_gemma":[0.9986206,0.00028637756,0.0000429531,0.00029494736,0.00042994187,0.0003251262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019374726,0.00022613107,0.00029418117,0.00054355594,0.00041664226,0.0001808226,0.00016436505,0.0000596189,0.00007673256],"category_scores_gemma":[0.00010998657,0.00015507151,0.000041230876,0.0011114444,0.0006485327,0.00032738835,0.00013525311,0.0007708003,0.000011522568],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005485677,0.0012519561,0.8445627,0.000009968099,0.0005839526,0.0001066317,0.0022322554,0.0000016354877,0.00014515965,0.000030269663,0.00022927998,0.14536051],"study_design_scores_gemma":[0.0061381543,0.0061120186,0.97811174,0.00004959273,0.00043036204,0.000035005563,0.0061131595,0.0021663683,0.00007516314,0.00007885147,0.0005151793,0.00017437583],"about_ca_topic_score_codex":0.00045968188,"about_ca_topic_score_gemma":0.0002347828,"teacher_disagreement_score":0.14518614,"about_ca_system_score_codex":0.000040667685,"about_ca_system_score_gemma":0.00020507608,"threshold_uncertainty_score":0.63236326},"labels":[],"label_agreement":null},{"id":"W2149698960","doi":"10.1186/alzrt89","title":"Validation of the relevant outcome scale for Alzheimer's disease: a novel multidomain assessment for daily medical practice","year":2011,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Merz Pharmaceuticals","keywords":"Intraclass correlation; Varimax rotation; Cronbach's alpha; Dementia; Psychology; Construct validity; Rating scale; Clinical Dementia Rating; Reliability (semiconductor); Clinical psychology; Exploratory factor analysis; Montreal Cognitive Assessment; Disease; Psychometrics; Psychiatry; Physical therapy; Medicine; Internal medicine; Developmental psychology","score_opus":0.2085296362897263,"score_gpt":0.4787416556604742,"score_spread":0.2702120193707479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149698960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7601063,0.018609088,0.069892325,0.08525898,0.0013116659,0.052024193,0.0007197018,0.00024353327,0.011834176],"genre_scores_gemma":[0.977373,0.0005967081,0.017387453,0.0010396347,0.0002454257,0.0027941207,0.000092971546,0.000079798636,0.00039085877],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9945352,0.0005965413,0.0006316046,0.0005566562,0.0028344349,0.000845534],"domain_scores_gemma":[0.9943486,0.002074227,0.0001861646,0.00077886746,0.0020704602,0.000541688],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007217478,0.00023070576,0.00039146378,0.00023018003,0.00038786276,0.000047404752,0.0006062442,0.0001393668,0.00053011696],"category_scores_gemma":[0.0019394766,0.00014859522,0.0003686904,0.0004778926,0.0005657063,0.00027183606,0.00020231449,0.0005477819,0.000015533034],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.051405605,0.027251694,0.42939532,0.00054205174,0.016189678,0.00006464567,0.005091024,0.0000030077426,0.08660472,0.0100252,0.018349532,0.3550775],"study_design_scores_gemma":[0.03261152,0.0074382788,0.6105569,0.00045721713,0.0027546172,0.000045961606,0.0025114457,0.0033160546,0.20865749,0.0031359596,0.12783779,0.00067673746],"about_ca_topic_score_codex":0.0001776953,"about_ca_topic_score_gemma":0.000009419178,"teacher_disagreement_score":0.35440078,"about_ca_system_score_codex":0.00006184998,"about_ca_system_score_gemma":0.0012342127,"threshold_uncertainty_score":0.60595375},"labels":[],"label_agreement":null},{"id":"W2152317386","doi":"10.1186/s13195-015-0123-4","title":"HIV effects on age-associated neurocognitive dysfunction: premature cognitive aging or neurodegenerative disease?","year":2015,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":147,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; National Institute on Aging; National Institutes of Health","keywords":"Neurocognitive; Cognitive decline; Disease; Medicine; Neurology; Affect (linguistics); Cognition; Neuroimaging; Aging brain; Geriatric psychiatry; Dementia; Psychiatry; Psychology; Pathology","score_opus":0.12918120518258983,"score_gpt":0.37272256637740747,"score_spread":0.24354136119481765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152317386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9012506,0.06452073,0.00008900686,0.009362291,0.0017883069,0.009419674,0.0011180729,0.00064805185,0.011803263],"genre_scores_gemma":[0.9881595,0.0008648402,0.000010108258,0.0011319995,0.00020435301,0.00094094296,0.0012854432,0.000075152864,0.007327692],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99293435,0.004190011,0.0002529127,0.00087214535,0.0004894551,0.0012611543],"domain_scores_gemma":[0.99527866,0.0025281704,0.00008065005,0.00042200251,0.0012972031,0.0003933161],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00096994074,0.00041587683,0.00042502495,0.00038087144,0.00072154985,0.0001296783,0.00036651216,0.00023061859,0.00056372024],"category_scores_gemma":[0.0017680017,0.0002867496,0.00015120025,0.0007591754,0.0005493622,0.0002139364,0.00016337694,0.0014276871,0.0053180354],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.07880637,0.008343279,0.009708661,0.00006258733,0.022926945,0.010048246,0.013291182,0.000030337429,0.042528532,0.00047599836,0.46454102,0.34923685],"study_design_scores_gemma":[0.07547859,0.034857247,0.13117602,0.0012760232,0.0009843133,0.000139232,0.0045925905,0.000053316136,0.55456835,0.0019708937,0.19247098,0.0024324134],"about_ca_topic_score_codex":0.00008021872,"about_ca_topic_score_gemma":0.00004657369,"teacher_disagreement_score":0.51203984,"about_ca_system_score_codex":0.00011901212,"about_ca_system_score_gemma":0.000621633,"threshold_uncertainty_score":0.99995846},"labels":[],"label_agreement":null},{"id":"W2153095386","doi":"10.1186/s13195-015-0110-9","title":"Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer’s disease mouse model","year":2015,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital","funders":"UCB Pharma; Dr. Ralph and Marian Falk Medical Research Trust; BrightFocus Foundation; National Institute on Aging; National Institutes of Health; National Institute of General Medical Sciences; Alzheimer's Association","keywords":"Ethosuximide; Genetically modified mouse; Memory impairment; Neuroscience; Transgene; Amyloid precursor protein; Medicine; Pharmacology; Epilepsy; Alzheimer's disease; Anticonvulsant; Psychology; Disease; Cognition; Biology; Pathology; Biochemistry","score_opus":0.2813919694416686,"score_gpt":0.44692109533321256,"score_spread":0.16552912589154395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153095386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92593795,0.065480284,0.000019347335,0.0026390748,0.00010896064,0.004029172,0.00023084892,0.00024030189,0.0013140786],"genre_scores_gemma":[0.9910556,0.00413767,0.0011738484,0.0011747866,0.00030528655,0.00086720404,0.00035283342,0.0002132424,0.00071949995],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99046403,0.0014535033,0.0007351053,0.0014165816,0.0036958333,0.002234951],"domain_scores_gemma":[0.9915737,0.00027561098,0.00012116507,0.0021060484,0.0012358414,0.004687664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0028536138,0.0006698481,0.00085254776,0.0010643299,0.0003551573,0.00020622152,0.0008455204,0.00027227507,0.00028938777],"category_scores_gemma":[0.00030404222,0.000568109,0.00033248012,0.0010341861,0.00075160223,0.0011458168,0.0003568437,0.0012946106,0.0007720196],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.1777207,0.06160731,0.27827138,0.0002632202,0.09866371,0.032336503,0.013647302,0.0036104126,0.017231027,0.0008498343,0.099793255,0.21600534],"study_design_scores_gemma":[0.22555944,0.03645527,0.26271358,0.0016934708,0.011610373,0.00069707376,0.015291814,0.17848882,0.22256862,0.019635538,0.014476206,0.010809803],"about_ca_topic_score_codex":0.0017867316,"about_ca_topic_score_gemma":0.00007933773,"teacher_disagreement_score":0.20533758,"about_ca_system_score_codex":0.00033141187,"about_ca_system_score_gemma":0.0032362116,"threshold_uncertainty_score":0.99967706},"labels":[],"label_agreement":null},{"id":"W2153149876","doi":"10.1186/s13195-015-0156-8","title":"Improved predictive ability of the Montreal Cognitive Assessment for diagnosing dementia in a community-based study","year":2015,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Taipei Medical University; Ministry of Science and Technology, Taiwan; National Science Council","keywords":"Geriatric psychiatry; Montreal Cognitive Assessment; Dementia; Neurology; Cognition; Medicine; Gerontology; Psychology; Cognitive impairment; Psychiatry; Internal medicine","score_opus":0.1615974769045858,"score_gpt":0.4615082680812088,"score_spread":0.299910791176623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153149876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98529845,0.0011502996,0.00052754214,0.0008349769,0.000060769078,0.0108282715,0.000057626577,0.000021793696,0.0012202924],"genre_scores_gemma":[0.996797,0.00003916524,0.00017402065,0.0002037745,0.000045909474,0.0026399423,0.000046892845,0.00003145122,0.000021803227],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9932461,0.0038195392,0.00044867655,0.00037416694,0.0014267537,0.00068478833],"domain_scores_gemma":[0.9944535,0.002394341,0.00010116446,0.0006244949,0.0021816108,0.00024489738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009239497,0.00020312297,0.00040615018,0.00031171602,0.00033059594,0.00005292567,0.00041475258,0.00008016871,0.000041188363],"category_scores_gemma":[0.00074892,0.00013833142,0.00016266684,0.00080062717,0.00049591664,0.0001331531,0.00023777812,0.0010898652,0.0000020336306],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0067918324,0.01253579,0.9403894,0.000049574246,0.0019242127,0.0000072527437,0.004662888,0.000006723402,0.003482881,0.000007892793,0.0002655958,0.029875977],"study_design_scores_gemma":[0.019709792,0.0133899385,0.9373254,0.00014942266,0.00027969072,8.402868e-7,0.013624457,0.0020884578,0.012681509,0.000506582,0.00012273279,0.00012113665],"about_ca_topic_score_codex":0.0036837861,"about_ca_topic_score_gemma":0.00091244874,"teacher_disagreement_score":0.02975484,"about_ca_system_score_codex":0.00016952796,"about_ca_system_score_gemma":0.0013506294,"threshold_uncertainty_score":0.5640992},"labels":[],"label_agreement":null},{"id":"W2154259512","doi":"10.1186/alzrt198","title":"Definitions of dementia and predementia states in Alzheimer's disease and vascular cognitive impairment: consensus from the Canadian conference on diagnosis of dementia","year":2013,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":199,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia Hospital; Jewish General Hospital; Centre Hospitalier de l’Université de Montréal; McGill University","funders":"National Institute on Aging; Canadian Institutes of Health Research","keywords":"Dementia; Disease; Cognitive impairment; Consensus conference; Cognitive decline; Gerontology; Medicine; Vascular dementia; Alzheimer's disease; Cognition; Psychiatry; Psychology; Pathology; Internal medicine","score_opus":0.10471005141454295,"score_gpt":0.35268808236717236,"score_spread":0.2479780309526294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154259512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9462075,0.04533803,0.000004226533,0.0037379977,0.000022695234,0.0035415047,0.0003859282,0.00001078096,0.00075133576],"genre_scores_gemma":[0.9656458,0.03251972,0.00009375317,0.00041352664,0.000024063136,0.0010555764,0.00021227961,0.000031080654,0.000004207654],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9963345,0.00079660455,0.0004924076,0.00052903895,0.001066984,0.00078046834],"domain_scores_gemma":[0.9963762,0.0014937965,0.000107259955,0.00039237365,0.0009826293,0.00064770464],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011582817,0.0002641066,0.000394893,0.00046557983,0.0003333333,0.00012459769,0.00021515907,0.00008746917,0.0020616883],"category_scores_gemma":[0.00018474781,0.00019771371,0.000100492296,0.00046216996,0.0013057899,0.00013254187,0.00015006698,0.00043092584,0.00003027655],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005996402,0.0009147885,0.9674092,0.000028338092,0.008741272,0.000027160819,0.0015249054,8.651316e-7,0.0004829886,0.0008542026,0.0014047651,0.018011874],"study_design_scores_gemma":[0.0043876874,0.0013338197,0.97923285,0.00039792416,0.0012806554,0.0000014425442,0.0025660181,0.00022382327,0.004688664,0.0054683704,0.00023323506,0.00018551075],"about_ca_topic_score_codex":0.13218278,"about_ca_topic_score_gemma":0.024367206,"teacher_disagreement_score":0.10781556,"about_ca_system_score_codex":0.000028515648,"about_ca_system_score_gemma":0.0006744002,"threshold_uncertainty_score":0.9988506},"labels":[],"label_agreement":null},{"id":"W2159161559","doi":"10.1186/alzrt200","title":"Role of emerging neuroimaging modalities in patients with cognitive impairment: a review from the Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012","year":2013,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Advanced Neuroimaging Techniques and Applications","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Douglas College; Parkwood Institute; Université de Sherbrooke; Université Laval; Montreal Neurological Institute and Hospital; St Joseph's Health Care; Western University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Alzheimer's Association","keywords":"Neuroimaging; Dementia; Positron emission tomography; Modalities; Magnetic resonance imaging; Cognition; Medicine; Psychology; Medical physics; Disease; Psychiatry; Radiology; Pathology","score_opus":0.33295218630888307,"score_gpt":0.4519153971752655,"score_spread":0.11896321086638245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159161559","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022946624,0.9875282,8.254579e-7,0.0026878978,0.000005459749,0.0070193633,0.0002747216,0.000009861504,0.0001790287],"genre_scores_gemma":[0.020451985,0.9764608,0.00008310032,0.00024086153,0.000016007993,0.002605735,0.0000920715,0.00004097605,0.00000843213],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99791455,0.0005483378,0.00041336092,0.00035845963,0.00041629229,0.0003490126],"domain_scores_gemma":[0.99727374,0.0014428952,0.0002307125,0.0005708702,0.00036520624,0.00011656961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031545322,0.00027685417,0.0008287676,0.00016932853,0.00016570814,0.000024574872,0.00021604756,0.000049663107,0.00012806499],"category_scores_gemma":[0.00005108209,0.000133169,0.00010962747,0.00037054098,0.00050591095,0.000037199723,0.000045809174,0.00037621747,0.0000037711438],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005278103,0.00030498207,0.004036708,0.00036710425,0.00095397426,0.0000033141678,0.00039487038,5.0461836e-8,0.0000010239789,0.00033821524,0.0005208887,0.9930261],"study_design_scores_gemma":[0.00255257,0.00310244,0.017070442,0.07660591,0.0033012503,0.000007967998,0.00056676636,0.0000313775,0.00013304771,0.0011156682,0.8949858,0.00052675226],"about_ca_topic_score_codex":0.040508755,"about_ca_topic_score_gemma":0.0027186465,"teacher_disagreement_score":0.99249935,"about_ca_system_score_codex":0.000060888033,"about_ca_system_score_gemma":0.00044010716,"threshold_uncertainty_score":0.9658806},"labels":[],"label_agreement":null},{"id":"W2159284980","doi":"10.1186/s13195-014-0054-5","title":"Age-related deficit accumulation and the risk of late-life dementia","year":2014,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Capital District Health Authority; Dalhousie University","funders":"Health Canada; University of Ottawa","keywords":"Dementia; Gerontology; Medicine; Psychology; Disease; Internal medicine","score_opus":0.10028370584347202,"score_gpt":0.40096012777787693,"score_spread":0.3006764219344049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159284980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97758746,0.01201842,0.00018319192,0.0022070801,0.000037644742,0.0014140183,0.0000033076942,0.000029571063,0.0065192915],"genre_scores_gemma":[0.99347097,0.005729827,0.000093321076,0.00021864749,0.00005975717,0.00008763389,0.00002187967,0.00002748198,0.00029046484],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99617356,0.00155087,0.0003543393,0.00030747746,0.0011207458,0.0004930147],"domain_scores_gemma":[0.9977082,0.0010497372,0.00009601297,0.00042627472,0.00051609,0.00020370354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005639021,0.0001454091,0.00031294156,0.00025458317,0.00030089577,0.00006777562,0.00019973343,0.00009272175,0.00065662526],"category_scores_gemma":[0.00056292553,0.00008677785,0.00012235844,0.0005134338,0.00093362195,0.000105306935,0.00011945289,0.0005595255,0.000078203164],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007185661,0.0007048529,0.6359624,0.000051642117,0.010174593,0.000014792509,0.0023198782,0.000033915338,0.011401035,0.0075229676,0.0017556681,0.3228726],"study_design_scores_gemma":[0.01931702,0.0016495392,0.9412312,0.00007249071,0.0007160248,0.0000073551864,0.00033370467,0.0065768864,0.009385881,0.008635175,0.011882604,0.00019214826],"about_ca_topic_score_codex":0.0005130398,"about_ca_topic_score_gemma":0.000016080025,"teacher_disagreement_score":0.32268044,"about_ca_system_score_codex":0.000010191661,"about_ca_system_score_gemma":0.00010502963,"threshold_uncertainty_score":0.7189586},"labels":[],"label_agreement":null},{"id":"W2165612785","doi":"10.1186/alzrt155","title":"Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome","year":2013,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":388,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; Baycrest Hospital; University of Toronto; Sunnybrook Health Science Centre; Centre for Addiction and Mental Health; Health Sciences Centre","funders":"Canadian Institutes of Health Research; Morris Kerzner Memorial Fund; University of Toronto; Sunnybrook Foundation","keywords":"Atrophy; Neuroscience; Pathological; Psychology; Disease; Executive dysfunction; Dysexecutive syndrome; Entorhinal cortex; Pathology; Medicine; Neuropsychology; Hippocampus; Cognition","score_opus":0.30271474559571726,"score_gpt":0.5000386355119139,"score_spread":0.1973238899161966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165612785","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0032371383,0.98803353,6.951539e-7,0.0004411905,0.00018980882,0.0075029917,0.00025989997,0.00007086944,0.0002638968],"genre_scores_gemma":[0.0113881845,0.98640877,0.000117676405,0.00015847094,0.00023751691,0.0012892248,0.00016041778,0.00017839359,0.00006133149],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9891165,0.004098271,0.0014719403,0.0015397774,0.0022825531,0.0014909694],"domain_scores_gemma":[0.99266684,0.0013294618,0.00047270214,0.002737213,0.0007331238,0.002060651],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.002541762,0.0009093252,0.0029453954,0.0004568504,0.00049567147,0.00015494553,0.0011829273,0.00046518125,0.00059869105],"category_scores_gemma":[0.0003456742,0.00048260624,0.0019312024,0.0009834964,0.0033130369,0.00019828342,0.001045827,0.0022237718,0.0005207257],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026079157,0.0017071596,0.009862051,0.0008659907,0.036746237,0.0009777375,0.00001845092,2.134331e-8,5.2720026e-7,0.000045567947,0.0044883317,0.9450271],"study_design_scores_gemma":[0.0031172177,0.0015539958,0.034295775,0.0063192537,0.015163623,0.00072761613,0.000032343487,0.000014435398,0.000014892357,0.0004688141,0.9374563,0.0008357482],"about_ca_topic_score_codex":0.00013812513,"about_ca_topic_score_gemma":0.0000022409827,"teacher_disagreement_score":0.9441914,"about_ca_system_score_codex":0.00006992115,"about_ca_system_score_gemma":0.0020642935,"threshold_uncertainty_score":0.99976254},"labels":[],"label_agreement":null},{"id":"W2166362985","doi":"10.1186/alzrt57","title":"A diverse portfolio of novel drug discovery efforts for Alzheimer's disease: Meeting report from the 11th International Conference on Alzheimer's Drug Discovery, 27-28 September 2010, Jersey City, NJ, USA","year":2010,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of British Columbia; University of Southern California; Alzheimer's Drug Discovery Foundation; Abbott Laboratories","keywords":"Drug discovery; Disease; Portfolio; Drug; Medicine; Pharmacology; Bioinformatics; Biology; Business; Pathology","score_opus":0.16588283891034594,"score_gpt":0.4120832851227125,"score_spread":0.24620044621236653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166362985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8290338,0.015411195,0.093903445,0.022644244,0.01663129,0.008651691,0.002560616,0.00042185237,0.010741858],"genre_scores_gemma":[0.97552615,0.000678234,0.020062761,0.0006561183,0.0011263996,0.00045180434,0.0004056533,0.00011916934,0.00097371446],"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9910945,0.0008299053,0.0012509897,0.0019213175,0.0036695688,0.0012336915],"domain_scores_gemma":[0.989613,0.0049322834,0.00083236175,0.002722826,0.0013779586,0.0005215911],"candidate_categories":["metaepi_narrow","scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.005920543,0.0007239742,0.00073597033,0.00048874324,0.00075389835,0.0015803068,0.0048435675,0.00017166836,0.00034871316],"category_scores_gemma":[0.00048712635,0.0005543417,0.00068447646,0.00094978296,0.001004942,0.0033629471,0.0019883323,0.0013498157,0.00005912823],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006437099,0.008822387,0.0600955,0.000059234615,0.029571807,0.0009734059,0.011633698,0.011335808,0.0216278,0.25851065,0.4497666,0.14116602],"study_design_scores_gemma":[0.017321888,0.0010047342,0.17920472,0.0014561812,0.002436805,0.00033404154,0.0029054738,0.37336922,0.0751569,0.13516054,0.20494027,0.0067092227],"about_ca_topic_score_codex":0.003525578,"about_ca_topic_score_gemma":0.0009347968,"teacher_disagreement_score":0.36203343,"about_ca_system_score_codex":0.00007075157,"about_ca_system_score_gemma":0.0014707553,"threshold_uncertainty_score":0.99969083},"labels":[],"label_agreement":null},{"id":"W2221424725","doi":"10.1186/s13195-015-0163-9","title":"Microstate connectivity alterations in patients with early Alzheimer’s disease","year":2015,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Parkinson Schweiz; Mach-Gaensslen Foundation of Canada; Fondation Botnar; Jacques und Gloria Gossweiler-Stiftung; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Novartis Foundation; Freiwillige Akademische Gesellschaft; Parrotia-Stiftung; National Science Foundation","keywords":"Ministate; Neuropsychology; Electroencephalography; Dementia; Audiology; Cognition; Psychology; Resting state fMRI; Logistic regression; Internal medicine; Neuroscience; Disease; Medicine","score_opus":0.20184065501068882,"score_gpt":0.37265460637404973,"score_spread":0.17081395136336092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2221424725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891126,0.0018495087,0.000028193048,0.006042641,0.00021509358,0.0015736154,0.00008008543,0.00009260239,0.0010056662],"genre_scores_gemma":[0.9978601,0.00007917007,0.0000715025,0.0014166703,0.00008900412,0.00032362607,0.000012113407,0.00005268957,0.000095163596],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9954034,0.0011935134,0.00024551078,0.00090344244,0.0014389904,0.0008151434],"domain_scores_gemma":[0.9948443,0.0034115852,0.00006516432,0.00063092937,0.00060486636,0.00044312293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011412562,0.00026679898,0.0002600539,0.00039989143,0.00047147274,0.00021103182,0.00041589056,0.000053462492,0.000049917067],"category_scores_gemma":[0.0025350864,0.00021633501,0.000059200538,0.0011664496,0.0006095144,0.0007907454,0.0001842183,0.00055784633,0.00025679296],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020781614,0.0051882546,0.88811314,0.000008728304,0.00085395237,0.00021882173,0.008360489,0.00058915006,0.0068938816,0.005082521,0.030079486,0.03382994],"study_design_scores_gemma":[0.008746817,0.0025157274,0.9313639,0.000042261156,0.000045213204,0.0000025038976,0.00019392848,0.00023833546,0.025714176,0.0049030595,0.025499545,0.00073455635],"about_ca_topic_score_codex":0.00062472234,"about_ca_topic_score_gemma":0.00022120762,"teacher_disagreement_score":0.043250713,"about_ca_system_score_codex":0.0000991674,"about_ca_system_score_gemma":0.0004081981,"threshold_uncertainty_score":0.8821886},"labels":[],"label_agreement":null},{"id":"W2257300023","doi":"10.1186/s13195-016-0172-3","title":"Reference tissue normalization in longitudinal 18F-florbetapir positron emission tomography of late mild cognitive impairment","year":2016,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; National Institute of Neurological Disorders and Stroke; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; University of California, San Diego; Pfizer; Biogen; BioClinica; University of Southern California; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; F. Hoffmann-La Roche; Vanderbilt University; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Alzheimer's Drug Discovery Foundation; Alzheimer's Association; Foundation for the National Institutes of Health; Meso Scale Diagnostics","keywords":"White matter; Positron emission tomography; Nuclear medicine; Cerebrospinal fluid; Normalization (sociology); Brainstem; Corpus callosum; Standardized uptake value; Correlation; Neuroimaging; Medicine; Pathology; Internal medicine; Radiology; Magnetic resonance imaging; Psychology; Neuroscience; Mathematics","score_opus":0.11076542304825587,"score_gpt":0.4185282206518577,"score_spread":0.3077627976036018,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2257300023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98735076,0.0059957756,0.00021848871,0.0014227536,0.000044285014,0.0019397443,0.000026896972,0.000035638117,0.0029656803],"genre_scores_gemma":[0.9941446,0.004355979,0.00009058356,0.00008803093,0.00006550722,0.00021890864,0.000060391354,0.000036203357,0.00093976135],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9958973,0.0006226043,0.00047110533,0.0005596562,0.0015649825,0.0008843541],"domain_scores_gemma":[0.9977271,0.00038246554,0.00009319138,0.00035485005,0.0011259647,0.00031640832],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001844051,0.0002380124,0.00038188332,0.000978125,0.00013601435,0.000033924276,0.00024194835,0.000115498944,0.00136748],"category_scores_gemma":[0.00009029334,0.00015527551,0.000109036795,0.0012028933,0.00041233405,0.00029121156,0.00013303556,0.00039863028,0.00010000053],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005560934,0.0013534803,0.67423177,0.00004885417,0.0006426236,0.00008574425,0.0004250446,2.1616302e-7,0.17667957,0.00007425892,0.0007134116,0.14018412],"study_design_scores_gemma":[0.0050275777,0.0035913175,0.5941154,0.0006381302,0.00005296329,0.00000943729,0.00013607195,0.000014869405,0.39465725,0.00023693955,0.0013711383,0.00014891781],"about_ca_topic_score_codex":0.00037718174,"about_ca_topic_score_gemma":0.000037011385,"teacher_disagreement_score":0.21797767,"about_ca_system_score_codex":0.000080660655,"about_ca_system_score_gemma":0.00026120804,"threshold_uncertainty_score":0.9995454},"labels":[],"label_agreement":null},{"id":"W2262785162","doi":"10.1186/s13195-016-0170-5","title":"Alzheimer’s Disease Assessment Scale–Cognitive subscale variants in mild cognitive impairment and mild Alzheimer’s disease: change over time and the effect of enrichment strategies","year":2016,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; Servier; Eisai; Pfizer; Novartis Pharmaceuticals Corporation; Synarc; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; BioClinica; Bristol-Myers Squibb; Eli Lilly and Company; Medpace; Biogen","keywords":"Dementia; Alzheimer's disease; Cognitive decline; Cognition; Psychology; Audiology; Alzheimer's Disease Neuroimaging Initiative; Neuroimaging; Disease; Cognitive impairment; Medicine; Internal medicine; Neuroscience","score_opus":0.061778836311648364,"score_gpt":0.39971923080919813,"score_spread":0.33794039449754976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2262785162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89472586,0.089115866,0.000020955451,0.004793096,0.00006746967,0.010163787,0.00030269753,0.00004796092,0.0007623011],"genre_scores_gemma":[0.9796703,0.016306005,0.000024303297,0.0003979377,0.00019774392,0.0030774015,0.0000960861,0.000087006316,0.00014320013],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9913381,0.002962505,0.000680385,0.0011912872,0.0023796381,0.0014480983],"domain_scores_gemma":[0.99407625,0.0034325025,0.00017692284,0.0005817732,0.0006241733,0.0011084056],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00463765,0.0006497526,0.00097208674,0.0006851047,0.00036866378,0.0001863033,0.00033221336,0.00014778494,0.0009809149],"category_scores_gemma":[0.00015554232,0.00036041284,0.0002644145,0.00075225014,0.002621097,0.0006487098,0.00047990083,0.00067410397,0.00006168448],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06438269,0.0022633784,0.7338863,0.00014377822,0.007467516,0.0003307363,0.0018308188,1.6816611e-7,0.0018828646,0.000269639,0.00068021275,0.1868619],"study_design_scores_gemma":[0.034033418,0.0042536305,0.9519612,0.0013271502,0.0019513798,0.000009319875,0.0005458923,0.00021243177,0.0046273796,0.00049472315,0.00015928592,0.0004241853],"about_ca_topic_score_codex":0.0005237756,"about_ca_topic_score_gemma":0.000038759128,"teacher_disagreement_score":0.2180749,"about_ca_system_score_codex":0.00008118388,"about_ca_system_score_gemma":0.0005541256,"threshold_uncertainty_score":0.99993235},"labels":[],"label_agreement":null},{"id":"W2398722408","doi":"10.1186/s13195-016-0191-0","title":"High tau levels in cerebrospinal fluid predict nursing home placement and rapid progression in Alzheimer’s disease","year":2016,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Uppsala Universitet; Göteborgs Universitet; Akademiska Sjukhuset","keywords":"Medicine; Cerebrospinal fluid; Quartile; Cohort; Dementia; Internal medicine; Lumbar puncture; Alzheimer's disease; Montreal Cognitive Assessment; Memory clinic; Disease; Confidence interval","score_opus":0.11175602340220321,"score_gpt":0.4133757954389734,"score_spread":0.3016197720367702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2398722408","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77838045,0.21061213,0.000014515544,0.006541213,0.0001118688,0.003869199,0.00011301004,0.000086756496,0.00027082852],"genre_scores_gemma":[0.98660135,0.0116990935,0.0003288035,0.00010900248,0.00021868825,0.00083720364,0.00006707418,0.00009737078,0.000041395513],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99352276,0.0008606161,0.0006132836,0.0011092133,0.002110281,0.0017838173],"domain_scores_gemma":[0.9968652,0.00039304435,0.00008306317,0.00085476233,0.00029452384,0.0015094163],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001574639,0.00047550685,0.0006238048,0.0010399498,0.00026695512,0.00009991203,0.00033309797,0.00017991781,0.00074218784],"category_scores_gemma":[0.00011292264,0.0003091046,0.0001353727,0.00089494267,0.0009286368,0.00048288773,0.00017492485,0.00059450616,0.00013527175],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021649504,0.0055746157,0.22982429,0.000048327092,0.007338441,0.001827473,0.00077178323,0.0000032272144,0.004087119,0.00041066762,0.0028225523,0.725642],"study_design_scores_gemma":[0.024967065,0.0045464337,0.954611,0.0026567488,0.00037898525,0.000035491266,0.00025642378,0.00015437604,0.008966736,0.0019952848,0.000864338,0.0005670937],"about_ca_topic_score_codex":0.00021503249,"about_ca_topic_score_gemma":0.00001709678,"teacher_disagreement_score":0.7250749,"about_ca_system_score_codex":0.000335251,"about_ca_system_score_gemma":0.0010327303,"threshold_uncertainty_score":0.9999361},"labels":[],"label_agreement":null},{"id":"W2512316306","doi":"10.1186/s13195-016-0200-3","title":"A call for comparative effectiveness research to learn whether routine clinical care decisions can protect from dementia and cognitive decline","year":2016,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nova Scotia Health Authority; Dalhousie University","funders":"National Institute on Aging; National Institutes of Health; Consortium canadien en neurodégénérescence associée au vieillissement; Alzheimer's Drug Discovery Foundation; American Heart Association","keywords":"Dementia; Geriatric psychiatry; Neurology; Cognitive decline; Medicine; Cognition; Cognitive aging; Gerontology; Psychology; Psychiatry; Pathology; Disease","score_opus":0.8764644796927571,"score_gpt":0.6725020171271233,"score_spread":0.20396246256563377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2512316306","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014913945,0.9668445,0.0021185419,0.0037608007,0.00035661546,0.020024374,0.0050073136,0.000040592266,0.0003558444],"genre_scores_gemma":[0.0056854626,0.9785344,0.0016248656,0.0007642909,0.0012736596,0.011277683,0.00043286136,0.00020757777,0.00019922615],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.97433627,0.01612968,0.0050418046,0.0023471864,0.00061461714,0.001530421],"domain_scores_gemma":[0.9240898,0.0709044,0.0012968065,0.0011641299,0.0017007007,0.00084416196],"candidate_categories":["metaresearch","metaepi_narrow","insufficient_payload"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.09253369,0.0006440682,0.004923419,0.0014078327,0.0010112346,0.00035815916,0.0011539321,0.00077214255,0.00036085548],"category_scores_gemma":[0.014913767,0.000565542,0.0006264576,0.00086306507,0.00070508406,0.00022789638,0.0006299198,0.0017578545,0.00228581],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008527701,0.00037172085,0.0021735001,0.0016189994,0.007669697,0.0000049493206,0.004834254,8.4069524e-7,5.4129043e-7,0.0021051932,0.009717706,0.97064984],"study_design_scores_gemma":[0.002786896,0.0013254075,0.0014218375,0.008541078,0.00013966941,0.0000018918029,0.00082478597,0.000023216844,0.0000036344393,0.0046427194,0.97965056,0.0006383245],"about_ca_topic_score_codex":0.004013821,"about_ca_topic_score_gemma":0.0015876828,"teacher_disagreement_score":0.97001153,"about_ca_system_score_codex":0.0005902641,"about_ca_system_score_gemma":0.0017315112,"threshold_uncertainty_score":0.9996796},"labels":[],"label_agreement":null},{"id":"W2520082135","doi":"10.1186/s13195-016-0207-9","title":"Drug development in Alzheimer’s disease: the path to 2025","year":2016,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":455,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Eli Lilly (Canada)","funders":"Biogen; Danone; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Sanofi; National Institute on Aging; Eli Lilly and Company; Alzheimer's Drug Discovery Foundation","keywords":"Drug development; Disease; Clinical trial; Standardization; Medicine; Risk analysis (engineering); Data sharing; Set (abstract data type); Computer science; Psychology; Drug; Alternative medicine; Psychiatry","score_opus":0.2568617205341319,"score_gpt":0.47926265956729147,"score_spread":0.22240093903315955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2520082135","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000003165709,0.9848508,0.0070164227,0.0034038401,0.0005259397,0.0035159315,0.000022363129,0.00009168569,0.000569856],"genre_scores_gemma":[0.00002149193,0.9873414,0.009267572,0.0004181926,0.00030567293,0.002168689,0.000023068618,0.000088787834,0.0003651104],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9881778,0.0053134733,0.0010233175,0.0015704304,0.002519973,0.001395035],"domain_scores_gemma":[0.9912456,0.005204275,0.00019709456,0.0023537618,0.00040392185,0.00059531594],"candidate_categories":["metaepi_narrow","open_science","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.008306857,0.0006921205,0.0011450151,0.0011126073,0.0004656954,0.0006124501,0.006654041,0.00014951946,0.00012825374],"category_scores_gemma":[0.00024566078,0.00039611646,0.00041864152,0.0031204077,0.00021495867,0.0004681209,0.002191136,0.0011225907,0.0019593455],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001948019,0.00010982311,0.0000022893148,0.000094716204,0.0006175937,0.000050159317,0.0006010643,0.00001665104,1.6471768e-7,0.006477795,0.00920058,0.98280966],"study_design_scores_gemma":[0.00021565224,0.000034256973,0.000098254604,0.0032180003,0.00004581131,0.0000046047558,0.0000075060893,0.00012640026,0.000008320237,0.00336549,0.99234176,0.0005339599],"about_ca_topic_score_codex":0.00008299985,"about_ca_topic_score_gemma":0.000029879046,"teacher_disagreement_score":0.9831412,"about_ca_system_score_codex":0.0002798864,"about_ca_system_score_gemma":0.0051126257,"threshold_uncertainty_score":0.9998491},"labels":[],"label_agreement":null},{"id":"W2551920754","doi":"10.1186/s13195-016-0220-z","title":"Conflicting cerebrospinal fluid biomarkers and progression to dementia due to Alzheimer’s disease","year":2016,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; Servier; Pfizer; Novartis Pharmaceuticals Corporation; Eisai; Synarc; U.S. Department of Defense; Meso Scale Diagnostics; BioClinica; Bristol-Myers Squibb; Eli Lilly and Company; Medpace; Biogen","keywords":"Biomarker; Dementia; Internal medicine; Oncology; Hazard ratio; Medicine; Cerebrospinal fluid; Cohort; Disease; Tau protein; Alzheimer's disease; Confidence interval; Biology","score_opus":0.09350682853503506,"score_gpt":0.44693916443316306,"score_spread":0.353432335898128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2551920754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93717533,0.021002207,0.0005846188,0.0336303,0.00013324685,0.0052362443,0.000030498592,0.00013248774,0.0020750565],"genre_scores_gemma":[0.994946,0.00097421405,0.0011948475,0.0013995828,0.00025111428,0.0008139989,0.000015204108,0.00007592858,0.0003291132],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9949896,0.0004693568,0.00037546153,0.0009234153,0.0018539106,0.0013882545],"domain_scores_gemma":[0.99613476,0.0002976164,0.00004382756,0.0006155365,0.00080711144,0.0021011587],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0022045881,0.00031242587,0.0003509905,0.0006920213,0.0004910605,0.00017760179,0.00032888673,0.000085929794,0.0013566677],"category_scores_gemma":[0.00028791724,0.00020140107,0.0001151022,0.000831024,0.00034909186,0.00023848578,0.00042902285,0.0002706791,0.0006237939],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006388708,0.00044362436,0.13712305,0.000018119288,0.0023479685,0.00021053544,0.00032710127,5.5177935e-8,0.1353219,0.00012856296,0.008620056,0.7090703],"study_design_scores_gemma":[0.00557383,0.005412142,0.730333,0.0006868313,0.0003735258,0.000046747882,0.00029563773,0.000027267899,0.13542464,0.00020412811,0.121130094,0.0004921606],"about_ca_topic_score_codex":0.00010144025,"about_ca_topic_score_gemma":0.000008190882,"teacher_disagreement_score":0.70857817,"about_ca_system_score_codex":0.00005330515,"about_ca_system_score_gemma":0.00034533517,"threshold_uncertainty_score":0.99955624},"labels":[],"label_agreement":null},{"id":"W2594937598","doi":"10.1186/s13195-017-0243-0","title":"Cost-effectiveness of cerebrospinal biomarkers for the diagnosis of Alzheimer’s disease","year":2017,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Medicine; Biomarker; Quality-adjusted life year; Neuroimaging; Population; Cohort; Disease; Medical diagnosis; Pediatrics; Internal medicine; Cost effectiveness; Intensive care medicine; Psychiatry; Pathology","score_opus":0.28565848342198763,"score_gpt":0.4916107993968779,"score_spread":0.20595231597489028,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2594937598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9067847,0.06534868,0.00054647715,0.006636314,0.00029440547,0.017767554,0.00024939852,0.00003475839,0.0023376988],"genre_scores_gemma":[0.99077815,0.0053594303,0.0001109969,0.000056035413,0.0001090758,0.0034404804,0.000029751329,0.00004376954,0.000072293864],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9966177,0.0005905907,0.00034156194,0.00042256963,0.0013318504,0.00069572864],"domain_scores_gemma":[0.99462694,0.0020780968,0.00017713,0.0012653358,0.001517417,0.00033508305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0046709324,0.00020097675,0.00043204147,0.00025171443,0.0007233427,0.00008771417,0.00076096464,0.00007543646,0.00039306315],"category_scores_gemma":[0.0008011561,0.00012927769,0.00036991277,0.00024967644,0.0016742622,0.0001898557,0.00022419944,0.00029166028,0.000016183123],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.017993731,0.0015175255,0.58358175,0.00021651403,0.008400357,0.000018245337,0.00015029675,0.0000010747876,0.010442945,0.00066095573,0.0025380896,0.37447852],"study_design_scores_gemma":[0.004677714,0.0018932937,0.80277497,0.00025484944,0.0005289462,0.0000018582303,0.00014902334,0.000112925365,0.18084908,0.0005789219,0.008063838,0.0001145644],"about_ca_topic_score_codex":0.0005598337,"about_ca_topic_score_gemma":0.000008788771,"teacher_disagreement_score":0.37436396,"about_ca_system_score_codex":0.000027923363,"about_ca_system_score_gemma":0.0005055257,"threshold_uncertainty_score":0.6168889},"labels":[],"label_agreement":null},{"id":"W2600216530","doi":"10.1186/s13195-017-0250-1","title":"DHA brain uptake and APOE4 status: a PET study with [1-11C]-DHA","year":2017,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; National Institute on Aging; Fonds de recherche du Québec; Alzheimer's Association","keywords":"Docosahexaenoic acid; Apolipoprotein E; Internal medicine; Cerebral blood flow; Endocrinology; Pathogenesis; Polyunsaturated fatty acid; Atrophy; Medicine; Fatty acid; Biology; Disease; Biochemistry","score_opus":0.1715552283429058,"score_gpt":0.4538910717625652,"score_spread":0.28233584341965945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2600216530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94069153,0.00903091,0.000008674208,0.043352682,0.00019402865,0.003400855,0.00003716115,0.000111280315,0.003172891],"genre_scores_gemma":[0.99533063,0.002172096,0.0007253114,0.00061946124,0.00034281655,0.00026124556,0.000013081192,0.000109286484,0.00042609326],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9933161,0.0012157798,0.0003490845,0.00091037166,0.0020164053,0.0021922314],"domain_scores_gemma":[0.9956189,0.00084064394,0.00012756724,0.0019056816,0.00051849434,0.0009887205],"candidate_categories":["metaepi_narrow","sts","scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.0042411583,0.0003443308,0.00046604945,0.00041984947,0.0031722123,0.0011694236,0.0010910538,0.000098092925,0.00041919196],"category_scores_gemma":[0.00058395544,0.00025288426,0.0000683156,0.00033019285,0.001180958,0.00066622265,0.00031210587,0.0014389335,0.00017654558],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.027435614,0.0038883658,0.15348646,0.00012917655,0.0028862236,0.0010531544,0.022478983,0.0000036800225,0.017514674,0.0006812045,0.08407259,0.6863699],"study_design_scores_gemma":[0.017646952,0.027615571,0.6515655,0.00021835296,0.00007367993,0.000086487096,0.01125462,0.0002631362,0.011653786,0.0012327055,0.277424,0.0009652123],"about_ca_topic_score_codex":0.006252655,"about_ca_topic_score_gemma":0.004252975,"teacher_disagreement_score":0.68540466,"about_ca_system_score_codex":0.000089333655,"about_ca_system_score_gemma":0.00050938234,"threshold_uncertainty_score":0.9999923},"labels":[],"label_agreement":null},{"id":"W2602908130","doi":"10.1186/s13195-017-0253-y","title":"Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain","year":2017,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":349,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Montreal Neurological Institute and Hospital; McGill University","funders":"Canadian Institutes of Health Research; Alzheimer's Association","keywords":"Selegiline; Monoamine oxidase B; Monoamine oxidase; Monoamine oxidase A; Neurology; Pharmacology; Medicine; Monoamine oxidase inhibitor; Geriatric psychiatry; Human brain; Clorgyline; Chemistry; Psychiatry; Parkinson's disease; Biochemistry; Internal medicine; Enzyme","score_opus":0.23033182064208652,"score_gpt":0.4330650590117566,"score_spread":0.2027332383696701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2602908130","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96943486,0.0023692609,0.0000018481812,0.018595405,0.0001706598,0.0010397916,0.000011026275,0.000065776345,0.008311394],"genre_scores_gemma":[0.9958889,0.0007264176,0.00003887596,0.001895963,0.00036318306,0.00018440238,0.0000050352282,0.00004884303,0.00084839814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99560267,0.0011025851,0.0003544518,0.0007713191,0.0011804521,0.0009884962],"domain_scores_gemma":[0.9970955,0.00094908965,0.00012114516,0.0015846831,0.00009431003,0.00015527036],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0025211629,0.00026871366,0.000249024,0.00030103515,0.0018065553,0.00078020466,0.0027648343,0.00010383837,0.00019919455],"category_scores_gemma":[0.0011379039,0.0001851121,0.0001249804,0.0005238703,0.0011361868,0.0005553365,0.00023737237,0.00092778355,0.00017555768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015969288,0.00059229526,0.00031053557,0.0000039746637,0.000040348037,0.00014345987,0.0032706766,0.0000018593116,0.8983609,0.0034970567,0.024669385,0.06894982],"study_design_scores_gemma":[0.0035282073,0.0006767371,0.037238833,0.000044977154,0.000005887943,0.000022890497,0.0016192781,0.00011260161,0.77527785,0.005978911,0.17500603,0.00048778873],"about_ca_topic_score_codex":0.00044430635,"about_ca_topic_score_gemma":0.00022355691,"teacher_disagreement_score":0.15033665,"about_ca_system_score_codex":0.000022986302,"about_ca_system_score_gemma":0.00012520979,"threshold_uncertainty_score":0.99949294},"labels":[],"label_agreement":null},{"id":"W2609123133","doi":"10.1186/s13195-017-0260-z","title":"Comparison of CSF markers and semi-quantitative amyloid PET in Alzheimer’s disease diagnosis and in cognitive impairment prognosis using the ADNI-2 database","year":2017,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Pfizer; Novartis Pharmaceuticals Corporation; Eisai; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Servier; BioClinica; Bristol-Myers Squibb; Eli Lilly and Company; Biogen","keywords":"Neurology; Medicine; Cognitive impairment; Geriatric psychiatry; Disease; Dementia; Amyloid β; Amyloid (mycology); Pathology; Internal medicine; Oncology; Psychiatry","score_opus":0.2604679279224127,"score_gpt":0.5005382193006511,"score_spread":0.24007029137823843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2609123133","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95970696,0.03340835,0.000009599844,0.0024428521,0.000029388342,0.004013986,0.00010148268,0.000010086787,0.00027730266],"genre_scores_gemma":[0.9866535,0.011975952,0.00025240076,0.00012344147,0.000033292305,0.0008682059,0.000044709428,0.000037905145,0.000010592593],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9958107,0.00100795,0.00049346435,0.00067010167,0.0011883242,0.00082946033],"domain_scores_gemma":[0.9969824,0.001385885,0.00017871505,0.0005578211,0.00048609555,0.0004090588],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0031853968,0.0002874048,0.0005541991,0.00056669797,0.0005208042,0.0002107618,0.00034633602,0.00005321993,0.00018827531],"category_scores_gemma":[0.0006430506,0.00020852359,0.00008324511,0.00042697752,0.0017874658,0.00048315575,0.0005033177,0.0007212245,0.000004781705],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0068581984,0.0017191041,0.96080685,0.000056679753,0.00097107573,0.00019728088,0.0018327179,0.0000010307049,0.0023013991,0.000038034395,0.00021543939,0.025002198],"study_design_scores_gemma":[0.0055960454,0.0014073408,0.96935576,0.0008570632,0.00034647304,0.000009900257,0.006912399,0.0023991365,0.012674255,0.00008877394,0.00013366748,0.00021915465],"about_ca_topic_score_codex":0.001846911,"about_ca_topic_score_gemma":0.00036751525,"teacher_disagreement_score":0.026946548,"about_ca_system_score_codex":0.000049497598,"about_ca_system_score_gemma":0.0003164523,"threshold_uncertainty_score":0.8503345},"labels":[],"label_agreement":null},{"id":"W2609756621","doi":"10.1186/s13195-017-0255-9","title":"Memory is preserved in older adults taking AT1 receptor blockers","year":2017,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Pfizer; Novartis Pharmaceuticals Corporation; Eisai; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Servier; BioClinica; Bristol-Myers Squibb; Eli Lilly and Company; Biogen","keywords":"Neurology; Geriatric psychiatry; Psychopharmacology; Angiotensin Receptor Blockers; Medicine; Psychology; Neuroscience; Psychiatry; Internal medicine","score_opus":0.13254310332247546,"score_gpt":0.4351353061778932,"score_spread":0.30259220285541777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2609756621","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9575596,0.0069615967,0.000002772978,0.015901,0.00013758594,0.0028092286,0.000009856333,0.000050475242,0.016567875],"genre_scores_gemma":[0.98852104,0.0035914516,0.00023880161,0.0007075472,0.0004027695,0.0004745446,0.000024531646,0.0000689217,0.00597037],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9951923,0.00045711017,0.00036338373,0.0007513605,0.001920841,0.0013150178],"domain_scores_gemma":[0.99705285,0.00022242533,0.00013311807,0.0014068835,0.0007632913,0.0004214188],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0025955073,0.00025909953,0.00038897814,0.00051790365,0.0006879071,0.00029762383,0.0008972857,0.00017315435,0.011046785],"category_scores_gemma":[0.00045506723,0.00021490546,0.00017391196,0.00035728782,0.00057601114,0.00041519298,0.00038225038,0.0010562203,0.00091106957],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0053371186,0.0016541784,0.3154262,0.00008207462,0.0012554806,0.00022927784,0.004009594,1.2061601e-7,0.0102475425,0.00001576369,0.06949934,0.5922433],"study_design_scores_gemma":[0.013596887,0.0012755283,0.7807603,0.00075479416,0.000037731865,0.000009355464,0.0014156856,0.00016569361,0.13536836,0.000104244325,0.066184744,0.00032666067],"about_ca_topic_score_codex":0.0022424557,"about_ca_topic_score_gemma":0.00011034408,"teacher_disagreement_score":0.5919166,"about_ca_system_score_codex":0.00008599732,"about_ca_system_score_gemma":0.00038389966,"threshold_uncertainty_score":0.99986684},"labels":[],"label_agreement":null},{"id":"W2743373469","doi":"10.1186/s13195-017-0283-5","title":"On the path to 2025: understanding the Alzheimer’s disease continuum","year":2017,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":557,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Eli Lilly (Canada)","funders":"National Institute on Aging","keywords":"Disease; Medicine; Biomarker; Natural history; Asymptomatic; Intensive care medicine; Neuroscience; Psychology; Pathology; Internal medicine; Biology","score_opus":0.5521856821984469,"score_gpt":0.5162792480049575,"score_spread":0.03590643419348938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2743373469","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000012309092,0.97045445,0.000011329271,0.009008242,0.0003238884,0.012893407,0.0003040202,0.00010554848,0.006886822],"genre_scores_gemma":[0.004134101,0.9885527,0.000014378832,0.0010137206,0.0009600884,0.0038502559,0.00025997736,0.00032099112,0.0008937695],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9883848,0.0028688617,0.0008529531,0.0015813092,0.003892658,0.0024194329],"domain_scores_gemma":[0.9871337,0.004423681,0.00035841335,0.005217354,0.00057566416,0.0022911988],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0041681672,0.001191146,0.0021490734,0.0007397256,0.0032218392,0.0009336286,0.0027606164,0.00037316213,0.0012532534],"category_scores_gemma":[0.00090650545,0.00054999103,0.0016377846,0.0010851348,0.0014428111,0.00018291622,0.0007044221,0.0029726957,0.004523285],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017793558,0.0010318898,0.000035491583,0.0004735581,0.08202772,0.0012774143,0.00026371956,1.6756454e-7,3.0773955e-7,0.005920187,0.19691272,0.71027744],"study_design_scores_gemma":[0.0012873181,0.0010978669,0.00010353996,0.007163079,0.0064204927,0.00002696244,0.00017971768,0.000006179259,0.0000044926846,0.0031160042,0.9800186,0.000575718],"about_ca_topic_score_codex":0.0001638618,"about_ca_topic_score_gemma":0.000022187845,"teacher_disagreement_score":0.7831059,"about_ca_system_score_codex":0.000471285,"about_ca_system_score_gemma":0.0037192006,"threshold_uncertainty_score":0.9996952},"labels":[],"label_agreement":null},{"id":"W2772130694","doi":"10.1186/s13195-017-0326-y","title":"Posterior atrophy predicts time to dementia in patients with amyloid-positive mild cognitive impairment","year":2017,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Seoul National University Bundang Hospital; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; DoD Alzheimer's Disease Neuroimaging Initiative; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Southern California; Seoul National University; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Dementia; Atrophy; Hazard ratio; Medicine; Internal medicine; Alzheimer's Disease Neuroimaging Initiative; Magnetic resonance imaging; Biomarker; Cohort; Pittsburgh compound B; Proportional hazards model; Pathology; Gastroenterology; Oncology; Disease; Confidence interval; Radiology","score_opus":0.04267115888408054,"score_gpt":0.3618026469236948,"score_spread":0.3191314880396143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2772130694","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849163,0.0008651845,0.000010073387,0.0023317623,0.000046530404,0.006394319,0.00009473743,0.00004085715,0.005300178],"genre_scores_gemma":[0.99676543,0.00013180514,0.00018200821,0.0008143488,0.00013196672,0.00065725634,0.0001241706,0.0000823484,0.0011106656],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9945125,0.00046887496,0.00037728675,0.0008707866,0.0023266017,0.001443949],"domain_scores_gemma":[0.99656725,0.00019085154,0.00011059049,0.0008294135,0.0015828935,0.0007189914],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0012949754,0.00037466834,0.0004940306,0.0006976795,0.0007259372,0.00035630818,0.00057524873,0.00011930201,0.0021485484],"category_scores_gemma":[0.00012797084,0.00028637899,0.00012426989,0.0004446801,0.0005503632,0.0004432359,0.00045586255,0.0006833391,0.0016928461],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024151918,0.002903742,0.9013913,0.000021132533,0.0029989637,0.00018334383,0.0008465929,5.5415114e-7,0.0014270324,0.0000041557983,0.0019352268,0.064136036],"study_design_scores_gemma":[0.016299821,0.015312643,0.957003,0.00048886985,0.00017044759,0.0000042697166,0.00013766799,0.000023929471,0.00916817,0.00002037499,0.001072514,0.00029826871],"about_ca_topic_score_codex":0.00036488162,"about_ca_topic_score_gemma":0.000033617445,"teacher_disagreement_score":0.06383777,"about_ca_system_score_codex":0.00013886232,"about_ca_system_score_gemma":0.00038030586,"threshold_uncertainty_score":0.9999588},"labels":[],"label_agreement":null},{"id":"W2785342662","doi":"10.1186/s13195-018-0346-2","title":"Early brain connectivity alterations and cognitive impairment in a rat model of Alzheimer’s disease","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"FP7 Health; European Regional Development Fund; Instituto de Salud Carlos III; McGill University; Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina; Fundació la Marató de TV3","keywords":"Neurology; Geriatric psychiatry; Cognitive impairment; Disease; Neuroscience; Cognition; Medicine; Neurochemistry; Psychology; Psychiatry; Internal medicine","score_opus":0.18905805347329818,"score_gpt":0.3986557124660355,"score_spread":0.2095976589927373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2785342662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98375165,0.0027921582,0.00030223493,0.010761915,0.00010653781,0.0015731374,0.000095541734,0.00004448666,0.00057230605],"genre_scores_gemma":[0.9972608,0.00027294946,0.00008061972,0.0018253028,0.00010509052,0.0003529935,0.0000025964105,0.000031480544,0.00006816599],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964325,0.0010766682,0.00028952895,0.0008000442,0.0008144569,0.00058683736],"domain_scores_gemma":[0.9914932,0.007411929,0.000074244505,0.00036285724,0.00043326017,0.00022446382],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014596139,0.00021959633,0.0002904975,0.00043034047,0.0005009108,0.00008497748,0.00022073464,0.000059407077,0.00006728462],"category_scores_gemma":[0.0036713146,0.00019943072,0.00007525791,0.0007519501,0.001540796,0.00047513304,0.00023887094,0.0003674702,0.00003713021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011547459,0.004519371,0.029283913,0.000037947557,0.0012782044,0.00010291074,0.0250385,0.00030622957,0.8331867,0.020936536,0.014896168,0.058866065],"study_design_scores_gemma":[0.008006293,0.00506737,0.11532876,0.00020038267,0.0001400844,0.000011744214,0.00077123515,0.05281746,0.77837574,0.036964614,0.0013426676,0.00097362685],"about_ca_topic_score_codex":0.00027931627,"about_ca_topic_score_gemma":0.00019380954,"teacher_disagreement_score":0.08604484,"about_ca_system_score_codex":0.000033178556,"about_ca_system_score_gemma":0.00029535126,"threshold_uncertainty_score":0.8132549},"labels":[],"label_agreement":null},{"id":"W2790746318","doi":"10.1186/s13195-018-0336-4","title":"Assessment of kallikrein 6 as a cross-sectional and longitudinal biomarker for Alzheimer’s disease","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Skånes universitetssjukhus; Stiftelsen Olle Engkvist Byggmästare; Demensförbundet; Alzheimer's Association","keywords":"Geriatric psychiatry; Biomarker; Medicine; Neurology; Cross-sectional study; Disease; Kallikrein; Internal medicine; Gerontology; Psychiatry; Pathology; Biology","score_opus":0.26532242405771844,"score_gpt":0.503435559908117,"score_spread":0.2381131358503985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790746318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9599931,0.034651082,0.00032752464,0.0013891733,0.00024814717,0.0017987309,0.00006148015,0.00005754224,0.001473177],"genre_scores_gemma":[0.99647146,0.00082832284,0.0010624316,0.00022445046,0.0005913319,0.0002032588,0.00008232784,0.00005014234,0.00048624186],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99734277,0.00013257204,0.00042591195,0.00057335175,0.0009544695,0.00057092455],"domain_scores_gemma":[0.9974133,0.00045275904,0.00009993067,0.00046763764,0.0011165276,0.00044984126],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014076644,0.00021632802,0.0003266786,0.00030390144,0.00041289369,0.000099142024,0.00018040379,0.00011530781,0.0009965701],"category_scores_gemma":[0.0001216402,0.00017993571,0.00019750807,0.00037877136,0.0010790969,0.0001926144,0.00008409843,0.00018491522,0.000027042975],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030589998,0.00047701568,0.9555945,0.000028541877,0.0020206694,0.00001454304,0.00018996972,9.498929e-7,0.0045430604,0.0042919097,0.0018310809,0.02794879],"study_design_scores_gemma":[0.0029757693,0.0014658973,0.96951854,0.000046297722,0.00015425587,0.00001672002,0.000026821377,0.0012468696,0.0049042846,0.0024204305,0.017050434,0.00017366411],"about_ca_topic_score_codex":0.00033883034,"about_ca_topic_score_gemma":0.000022795164,"teacher_disagreement_score":0.03647835,"about_ca_system_score_codex":0.000032707696,"about_ca_system_score_gemma":0.0006342599,"threshold_uncertainty_score":0.9999167},"labels":[],"label_agreement":null},{"id":"W2795503875","doi":"10.1186/s13195-017-0333-z","title":"A novel language-neutral Visual Cognitive Assessment Test (VCAT): validation in four Southeast Asian countries","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Dementia; Cognition; Population; Medicine; Cohort; Psychology; Physical therapy; Disease; Psychiatry; Internal medicine; Environmental health","score_opus":0.09089356990288816,"score_gpt":0.4573445860478574,"score_spread":0.3664510161449692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795503875","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97366905,0.00085167104,0.0005007347,0.0035266706,0.000085335494,0.0023819758,0.000056859564,0.00007190584,0.01885577],"genre_scores_gemma":[0.9969155,0.00029280467,0.0002770746,0.00042911244,0.0005632941,0.000396886,0.0001114926,0.000058988127,0.0009548088],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9957682,0.00040697047,0.00037432133,0.0006178421,0.0017134182,0.001119246],"domain_scores_gemma":[0.9971098,0.0007438359,0.00006487965,0.00030780883,0.00144826,0.00032545594],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002923705,0.00026018007,0.00033860083,0.0007298102,0.00032097116,0.00021171912,0.00024394465,0.00014803754,0.0015957869],"category_scores_gemma":[0.00030165302,0.00021776547,0.0001057228,0.0009827252,0.00078133005,0.0002839019,0.0001303333,0.000878841,0.0005869166],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00541298,0.0063548246,0.64899945,0.0000892913,0.002164059,0.00048292874,0.011621087,2.7310512e-7,0.14073807,0.00079520495,0.0014022528,0.1819396],"study_design_scores_gemma":[0.010348358,0.00726654,0.8237203,0.00034512125,0.00011274129,0.00007898507,0.014445209,0.0002607049,0.14037827,0.0002232919,0.0024572143,0.00036329997],"about_ca_topic_score_codex":0.0006636607,"about_ca_topic_score_gemma":0.00028826002,"teacher_disagreement_score":0.18157631,"about_ca_system_score_codex":0.000118451455,"about_ca_system_score_gemma":0.0008844537,"threshold_uncertainty_score":0.9993169},"labels":[],"label_agreement":null},{"id":"W2804074264","doi":"10.1186/s13195-018-0376-9","title":"Distinct patterns of brain atrophy in Genetic Frontotemporal Dementia Initiative (GENFI) cohort revealed by visual rating scales","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Université Laval; Health Sciences Centre; Occupational Cancer Research Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Fondazione Antonio Carlo Monzino; Associazione Italiana Ricerca Alzheimer; Medical Research Council; University College London Hospitals NHS Foundation Trust; Ministero della Salute; Alzheimer’s Research UK; Brain Research Trust; Wolfson Foundation; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; University College London; Wellcome Trust","keywords":"Frontotemporal dementia; C9orf72; Atrophy; Psychology; Temporal lobe; Semantic dementia; Frontotemporal lobar degeneration; Pathology; Neuroscience; Dementia; Audiology; Medicine; Disease; Epilepsy","score_opus":0.10180068298924695,"score_gpt":0.4125724547658383,"score_spread":0.3107717717765914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2804074264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98878574,0.006469486,0.00027967044,0.0018298829,0.00005691031,0.0019600433,0.000045420293,0.000034545996,0.00053831184],"genre_scores_gemma":[0.9973777,0.00070269004,0.0007091303,0.0003145894,0.0003893662,0.00021938096,0.00008032209,0.0000805762,0.00012626409],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9940453,0.0014760561,0.00077566726,0.000710873,0.0018778564,0.0011142166],"domain_scores_gemma":[0.9976245,0.0005023821,0.00015022824,0.00057702494,0.0007847401,0.00036112632],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0022259331,0.0003000593,0.0006307394,0.00039188412,0.00022914467,0.00006298636,0.00045014863,0.00018543133,0.0014429125],"category_scores_gemma":[0.00028540567,0.00024294753,0.00014285419,0.00076867506,0.00085263146,0.00018464746,0.0002511521,0.0007757585,0.00009809268],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012636414,0.00045086376,0.88562804,0.000028109918,0.0011396443,0.000054766864,0.00090827147,3.6981373e-7,0.080926485,0.000012442775,0.004748852,0.024838507],"study_design_scores_gemma":[0.0033151507,0.0029826162,0.9825759,0.0001811033,0.000043478667,0.000006335219,0.00017632023,0.0004946653,0.008920859,0.00014169709,0.0009352636,0.0002266134],"about_ca_topic_score_codex":0.0037120252,"about_ca_topic_score_gemma":0.0005758341,"teacher_disagreement_score":0.096947856,"about_ca_system_score_codex":0.000141276,"about_ca_system_score_gemma":0.00030363037,"threshold_uncertainty_score":0.9994699},"labels":[],"label_agreement":null},{"id":"W2806853868","doi":"10.1186/s13195-018-0363-1","title":"A double-blind placebo-controlled cross-over clinical trial of DONepezil In Posterior cortical atrophy due to underlying Alzheimer's Disease: DONIPAD study","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Pfizer UK; Eisai Canada; Eisai; National Institute for Health and Care Research; Pfizer","keywords":"Donepezil; Placebo; Medicine; Atrophy; Internal medicine; Clinical trial; Neuropsychology; Anesthesia; Surgery; Disease; Dementia; Cognition; Psychiatry; Pathology","score_opus":0.3248810206919388,"score_gpt":0.5452918722827699,"score_spread":0.22041085159083107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806853868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97580373,0.002389335,0.0000343713,0.0014509493,0.00038109304,0.018833665,0.000014167446,0.000050501476,0.0010421972],"genre_scores_gemma":[0.9960201,0.00020957312,0.0001366133,0.00042139165,0.00084428047,0.0019738013,0.000019066592,0.00008838944,0.00028680885],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9894942,0.002744334,0.0017502434,0.0012406053,0.0032123954,0.0015582236],"domain_scores_gemma":[0.9939667,0.0017766631,0.00017876305,0.0011886422,0.0015966248,0.0012925934],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0102874525,0.00044871334,0.0014703872,0.0010883731,0.0003402302,0.00028458794,0.00070137787,0.00022953024,0.0015805332],"category_scores_gemma":[0.00074833503,0.000346266,0.0005208312,0.001594498,0.0013039869,0.0002898705,0.0004743491,0.0013958267,0.0003473823],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.85157174,0.008036343,0.103327304,0.000010972237,0.003912308,0.00042394878,0.0008794895,6.9526135e-7,0.0011270258,0.000041405754,0.0002537118,0.030415067],"study_design_scores_gemma":[0.5999864,0.031141184,0.36576474,0.000090796435,0.0005017963,0.00000858867,0.00043376719,0.00013295395,0.0007716393,0.00009757086,0.00078840944,0.00028217855],"about_ca_topic_score_codex":0.00054152036,"about_ca_topic_score_gemma":0.00019916562,"teacher_disagreement_score":0.26243743,"about_ca_system_score_codex":0.00008369786,"about_ca_system_score_gemma":0.0012694239,"threshold_uncertainty_score":0.9998989},"labels":[],"label_agreement":null},{"id":"W2809215238","doi":"10.1186/s13195-018-0384-9","title":"Immunotherapy to improve cognition and reduce pathological species in an Alzheimer’s disease mouse model","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Quest University Canada","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institute on Aging; National Institutes of Health; Alzheimer's Association","keywords":"Immunohistochemistry; Immunoprecipitation; Pathological; Antibody; Alzheimer's disease; Pathology; Endogeny; Medicine; Chemistry; Disease; Immunology; Internal medicine","score_opus":0.18646509859574623,"score_gpt":0.4310436937608998,"score_spread":0.24457859516515357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809215238","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95965296,0.032863077,0.00004659241,0.00267463,0.00005351299,0.003365296,0.00016087585,0.00012206486,0.0010609914],"genre_scores_gemma":[0.9910804,0.0052471776,0.0010629456,0.0010023691,0.00040138332,0.0007753753,0.00013876637,0.000100905294,0.00019065264],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9951938,0.0005873237,0.00042564716,0.0011089619,0.0013477231,0.0013365756],"domain_scores_gemma":[0.99623287,0.0001675242,0.000052681535,0.0010069967,0.000815627,0.0017242901],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011551961,0.00041279072,0.00049566635,0.00066186424,0.00042321693,0.00019305431,0.00035497983,0.00017537488,0.00039016307],"category_scores_gemma":[0.000113774164,0.00032419286,0.00013057743,0.0006960576,0.0010600995,0.00046259217,0.000179712,0.0006272337,0.0002753193],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.08938627,0.014974121,0.04294113,0.00004735759,0.019468397,0.0018280376,0.006440378,0.000021056192,0.4665624,0.0017589347,0.005529355,0.35104257],"study_design_scores_gemma":[0.0424661,0.0376011,0.4721498,0.00043520372,0.0016491262,0.0000931989,0.0023421217,0.0118417945,0.40541527,0.017192537,0.005875046,0.0029387432],"about_ca_topic_score_codex":0.0001320189,"about_ca_topic_score_gemma":0.00003614982,"teacher_disagreement_score":0.42920864,"about_ca_system_score_codex":0.00008344372,"about_ca_system_score_gemma":0.0005575367,"threshold_uncertainty_score":0.999921},"labels":[],"label_agreement":null},{"id":"W2882991683","doi":"10.1186/s13195-018-0382-y","title":"The Toronto Cognitive Assessment (TorCA): normative data and validation to detect amnestic mild cognitive impairment","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Mental Health Research Canada; Toronto Rehabilitation Institute; Centre for Addiction and Mental Health; Sunnybrook Health Science Centre; St. Michael's Hospital; Toronto Dementia Research Alliance; Parkwood Institute; Lawson Health Research Institute; Toronto Western Hospital; Dalhousie University; University of Toronto; Health Sciences Centre; Occupational Cancer Research Centre; University Health Network; Baycrest Hospital; Sunnybrook Hospital; Institute for Work & Health; Mount Sinai Hospital","funders":"National Institute on Aging; University of Toronto; Dalhousie University; Sunnybrook Foundation; Canadian Institutes of Health Research; Sunnybrook Research Institute; National Alzheimer's Coordinating Center; Morris Kerzner Memorial Fund; Ontario Brain Institute; Fondation Brain Canada; Dalhousie Medical Research Foundation","keywords":"Normative; Cognitive impairment; Cognition; Psychology; Cognitive Assessment System; Medicine; Cognitive psychology; Psychiatry; Political science","score_opus":0.14242016375613475,"score_gpt":0.47617390296828216,"score_spread":0.3337537392121474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2882991683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95713514,0.011817629,0.002773731,0.0061053736,0.00024056446,0.009511594,0.00023055928,0.00011062248,0.012074768],"genre_scores_gemma":[0.99278545,0.003969196,0.00041938774,0.00083985814,0.00047705893,0.00079488824,0.00026160662,0.000054758508,0.00039781892],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99417526,0.0012822098,0.00042107372,0.00089180394,0.0020671037,0.0011625491],"domain_scores_gemma":[0.9938696,0.0020713098,0.00008742399,0.00079106825,0.0025436317,0.0006369574],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.004780335,0.00032667126,0.0003554923,0.00020515887,0.0013275619,0.00038735912,0.00056350575,0.000098305085,0.0007752653],"category_scores_gemma":[0.00057063403,0.00021937706,0.000069078764,0.0006008223,0.0010998232,0.00058797543,0.00083087775,0.00056201214,0.00034310305],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009839531,0.0010529605,0.03312408,0.000038823364,0.0048538055,0.000060147573,0.0055566803,6.4936195e-8,0.0037378701,0.00013787729,0.013637646,0.9279605],"study_design_scores_gemma":[0.012860477,0.02477324,0.84710616,0.00064047665,0.0006914592,0.000080159225,0.018316548,0.000825645,0.066621386,0.0008671548,0.026483862,0.00073340564],"about_ca_topic_score_codex":0.00086663506,"about_ca_topic_score_gemma":0.00053419574,"teacher_disagreement_score":0.9272271,"about_ca_system_score_codex":0.0001986777,"about_ca_system_score_gemma":0.0005850108,"threshold_uncertainty_score":0.9999726},"labels":[],"label_agreement":null},{"id":"W2883056534","doi":"10.1186/s13195-018-0392-9","title":"Discovery and validation of autosomal dominant Alzheimer’s disease mutations","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institutes of Health; Fleni; Foundation for Biomedical Research and Innovation; Deutsches Zentrum für Neurodegenerative Erkrankungen; Korea Health Industry Development Institute; National Institute on Aging; Fidelity Biosciences; Hope Center for Neurological Disorders; Japan Agency for Medical Research and Development","keywords":"Neurology; Geriatric psychiatry; Disease; Medicine; Human genetics; Alzheimer's disease; Genetics; Bioinformatics; Neuroscience; Biology; Pathology; Psychiatry; Gene","score_opus":0.11263726910804712,"score_gpt":0.41466974389499034,"score_spread":0.30203247478694323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883056534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9244716,0.069861405,0.000057061854,0.0019515295,0.00008915455,0.0019879164,0.00012440344,0.000053399675,0.0014034932],"genre_scores_gemma":[0.99607044,0.0026232945,0.0003464917,0.00008540061,0.00029569812,0.00022909977,0.00018405788,0.000057180667,0.00010834541],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9964948,0.00040775858,0.00038467234,0.0005828439,0.0013656145,0.0007642925],"domain_scores_gemma":[0.99718106,0.00035300484,0.00008971631,0.0007244746,0.00086169824,0.0007900384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073344895,0.00025802338,0.00037683852,0.00046896754,0.00043138076,0.000108447806,0.00020697035,0.00009108273,0.00027581886],"category_scores_gemma":[0.00014485129,0.00019731416,0.00016039297,0.000665162,0.0015664408,0.0005434531,0.00014011665,0.00029692496,0.0001639635],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.04931252,0.015647568,0.42438644,0.0002667887,0.14882074,0.0016926324,0.0066606095,0.000007834564,0.05802271,0.013177845,0.014623241,0.26738107],"study_design_scores_gemma":[0.014157418,0.0069983755,0.5031127,0.00038135625,0.0036260362,0.000075564014,0.00077909295,0.00076830055,0.45628682,0.0076695615,0.0053792787,0.0007655578],"about_ca_topic_score_codex":0.00028151786,"about_ca_topic_score_gemma":0.0000072749835,"teacher_disagreement_score":0.39826408,"about_ca_system_score_codex":0.000038367394,"about_ca_system_score_gemma":0.0008386896,"threshold_uncertainty_score":0.8046238},"labels":[],"label_agreement":null},{"id":"W2885022815","doi":"10.1186/s13195-018-0402-y","title":"In vivo quantification of neurofibrillary tangles with [18F]MK-6240","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":196,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Douglas Mental Health University Institute; McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Alzheimer Society Research Program; Canadian Institutes of Health Research; Alzheimer Society; Weston Brain Institute; Consortium canadien en neurodégénérescence associée au vieillissement; Alzheimer's Association","keywords":"In vivo; Neurology; Magnetic resonance imaging; Positron emission tomography; Binding potential; Pathology; Nuclear medicine; Alzheimer's disease; Medicine; Neuroimaging; Neuroscience; Chemistry; Biology; Disease; Radiology","score_opus":0.13288898460857337,"score_gpt":0.4163449334955353,"score_spread":0.2834559488869619,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885022815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95179826,0.035340846,0.00002541754,0.002367261,0.00006570019,0.0019604475,0.00003670147,0.000054941436,0.008350443],"genre_scores_gemma":[0.9966858,0.0023232398,0.00027202308,0.00014539846,0.00021490282,0.00011933555,0.000026234296,0.000058983176,0.00015408959],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966035,0.00040650842,0.000323473,0.00051812315,0.0013943495,0.0007540622],"domain_scores_gemma":[0.9975989,0.00025239622,0.00007157469,0.0008327491,0.000870611,0.000373803],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007771579,0.00021103641,0.00036851125,0.00058082945,0.00015856973,0.00003620739,0.00020796718,0.00008251382,0.0007265447],"category_scores_gemma":[0.00006472475,0.00015011693,0.00009033605,0.0012335683,0.0009755172,0.0002473099,0.00006541351,0.00030531266,0.000211931],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.063714296,0.012138879,0.38786805,0.00027477203,0.05933205,0.004321023,0.004390987,0.000009547441,0.3078613,0.0057930867,0.050956305,0.103339694],"study_design_scores_gemma":[0.009807853,0.011932185,0.12798089,0.0003237989,0.00032962378,0.00018156762,0.0006184387,0.00032078213,0.8167996,0.0011976692,0.030046096,0.00046153253],"about_ca_topic_score_codex":0.0007523032,"about_ca_topic_score_gemma":0.00006251036,"teacher_disagreement_score":0.50893825,"about_ca_system_score_codex":0.000045238237,"about_ca_system_score_gemma":0.0005279396,"threshold_uncertainty_score":0.7955155},"labels":[],"label_agreement":null},{"id":"W2885700079","doi":"10.1186/s13195-018-0405-8","title":"Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; Medical Research Council; Brain Research Trust; Wolfson Foundation; European Commission; Rosetrees Trust; University College London; UK Dementia Research Institute; National Institute for Health and Care Research; Alzheimer's Society; Brain Research UK; Weston Brain Institute; Dementias Platform UK; Association for Frontotemporal Degeneration","keywords":"Frontotemporal dementia; Cerebrospinal fluid; Biomarker; Medicine; C9orf72; Frontotemporal lobar degeneration; Neurology; TREM2; Internal medicine; Pathology; Tau protein; Oncology; Dementia; Disease; Alzheimer's disease; Biology; Genetics; Psychiatry; Inflammation; Microglia","score_opus":0.21358321097969354,"score_gpt":0.3778042727406122,"score_spread":0.16422106176091864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885700079","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995212,0.0015470627,0.00061572006,0.0013058321,0.00023301125,0.0006581442,0.000014003025,0.00007428316,0.0003399466],"genre_scores_gemma":[0.9967625,0.00083070743,0.00042251748,0.0013161097,0.00014883885,0.00007994619,0.0000040218906,0.000035979843,0.00039938785],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963117,0.0010902395,0.0003533369,0.00079548475,0.00076749065,0.0006817511],"domain_scores_gemma":[0.99908423,0.00016800984,0.000055082714,0.0003917321,0.000094176496,0.00020676875],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00067991257,0.00021371784,0.00020666294,0.00020373923,0.00043727068,0.00022787885,0.00039651387,0.00010663646,0.0009679429],"category_scores_gemma":[0.00010783662,0.0001798096,0.000045200264,0.0004006417,0.0004728498,0.00025951982,0.00014893558,0.00035788715,0.00019074688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014211542,0.00012994786,0.0017671918,0.0000014543227,0.000010278587,0.00003712438,0.00023662357,6.470399e-7,0.98329663,0.0007125143,0.0035882597,0.010077226],"study_design_scores_gemma":[0.001436864,0.0011282744,0.029691529,0.0000054105462,0.000005752831,0.000026078347,0.000019091343,0.0013011458,0.95321834,0.0014125953,0.011529194,0.00022572196],"about_ca_topic_score_codex":0.000041832045,"about_ca_topic_score_gemma":0.000039969043,"teacher_disagreement_score":0.030078275,"about_ca_system_score_codex":0.000017799162,"about_ca_system_score_gemma":0.000056130983,"threshold_uncertainty_score":0.9999453},"labels":[],"label_agreement":null},{"id":"W2887353432","doi":"10.1186/s13195-018-0407-6","title":"Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer’s disease","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute on Aging; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health; Alzheimer's Association; Chongqing Medical University; Weston Brain Institute; Consortium canadien en neurodégénérescence associée au vieillissement; Alzheimer's Disease Neuroimaging Initiative","keywords":"Neurology; Neuroscience; Cerebrospinal fluid; Cognitive impairment; Disease; Medicine; Degeneration (medical); Pathology; Psychology","score_opus":0.08447353320381283,"score_gpt":0.38495431431269855,"score_spread":0.3004807811088857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887353432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781318,0.012018276,0.000011683694,0.0035257773,0.00005321767,0.005538917,0.000041101255,0.000049935417,0.0006292994],"genre_scores_gemma":[0.9957537,0.001157148,0.0000855181,0.0008144179,0.00016955388,0.0015679905,0.0000975288,0.00006932276,0.00028482664],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9943203,0.0010862284,0.00057480327,0.0009642494,0.0016227936,0.0014316615],"domain_scores_gemma":[0.997691,0.00023453204,0.00008192816,0.0003828291,0.0009685181,0.0006412104],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0022839827,0.00038767437,0.00048802927,0.0010278132,0.0003256575,0.0001559963,0.00023068541,0.00019985808,0.0011527984],"category_scores_gemma":[0.00026909675,0.00034023827,0.000112449015,0.001310252,0.0007272625,0.0003404306,0.00020167987,0.0008140295,0.00021628986],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024633214,0.007296627,0.86046445,0.00009194907,0.004132202,0.0007860833,0.0058801677,7.108905e-7,0.05676771,0.0003150351,0.0027922431,0.036839593],"study_design_scores_gemma":[0.014173318,0.007859051,0.89933133,0.0009168976,0.00021656736,0.000013414382,0.0009358957,0.0014585564,0.07353315,0.00057395286,0.0005066415,0.00048122904],"about_ca_topic_score_codex":0.0007667598,"about_ca_topic_score_gemma":0.0005178966,"teacher_disagreement_score":0.038866863,"about_ca_system_score_codex":0.00019072837,"about_ca_system_score_gemma":0.0007342183,"threshold_uncertainty_score":0.999905},"labels":[],"label_agreement":null},{"id":"W2889336384","doi":"10.1186/s13195-018-0420-9","title":"Inter-network connectivity and amyloid-beta linked to cognitive decline in preclinical Alzheimer’s disease: a longitudinal cohort study","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Genentech; National Institutes of Health; IXICO; H. Lundbeck A/S; Servier; Pfizer; Biogen; BioClinica; Alzheimer Nederland; Eisai; F. Hoffmann-La Roche; Universiteit Maastricht; Deutsche Forschungsgemeinschaft; Northern California Institute for Research and Education; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; University of Southern California; European Commission; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Internationale Stichting Alzheimer Onderzoek; Bristol-Myers Squibb; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Cognitive decline; Cognition; Episodic memory; Neurology; Cohort; Alzheimer's disease; Disease; Dementia; Memory impairment; Psychology; Medicine; Effects of sleep deprivation on cognitive performance; Neuroscience; Internal medicine","score_opus":0.27025558936520305,"score_gpt":0.4574811196104965,"score_spread":0.18722553024529343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889336384","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97997844,0.0034916347,0.00011725893,0.009889342,0.00048063448,0.005133039,0.00004243961,0.00012462011,0.00074261514],"genre_scores_gemma":[0.9936388,0.00045457442,0.000064364416,0.0036104438,0.00093660475,0.0011392237,0.000004279986,0.000067048204,0.00008467112],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99130696,0.0031636015,0.00059528317,0.0021944938,0.0014949151,0.0012447229],"domain_scores_gemma":[0.97313833,0.02465108,0.00010675522,0.00080531096,0.00070548477,0.0005930323],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006214493,0.00044351319,0.0007000057,0.00043523803,0.0008608554,0.00023898925,0.00066524895,0.00012496358,0.00022204363],"category_scores_gemma":[0.012090249,0.00039514588,0.000119527154,0.0018032483,0.0016228065,0.00039412852,0.0013377208,0.0010556536,0.00029638645],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007139106,0.0020426249,0.96298003,0.0000034890556,0.00085748924,0.00012668902,0.0011682111,0.000008027658,0.00073605386,0.00030332725,0.0035707296,0.021064235],"study_design_scores_gemma":[0.0026259846,0.004074991,0.9852044,0.000075897005,0.000115571114,0.000008157924,0.00025470555,0.00030169068,0.0013274476,0.001852235,0.0037246202,0.00043432112],"about_ca_topic_score_codex":0.0006957548,"about_ca_topic_score_gemma":0.003552125,"teacher_disagreement_score":0.022224361,"about_ca_system_score_codex":0.00007082876,"about_ca_system_score_gemma":0.0002504483,"threshold_uncertainty_score":0.99985003},"labels":[],"label_agreement":null},{"id":"W2891222261","doi":"10.1186/s13195-018-0408-5","title":"Is intracranial volume a suitable proxy for brain reserve?","year":2018,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Alzheimer Nederland; Internationale Stichting Alzheimer Onderzoek; Vanderbilt University Medical Center","keywords":"Cognitive reserve; Proxy (statistics); Brain size; Medicine; Neurology; Operationalization; Neuroscience; Cognition; Disease; Psychology; Pathology; Dementia; Computer science; Magnetic resonance imaging; Radiology; Machine learning","score_opus":0.43036771459980444,"score_gpt":0.48305559434712775,"score_spread":0.05268787974732331,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891222261","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000012858308,0.9800109,0.000039027083,0.009777461,0.0007966741,0.0073259925,0.000442522,0.00015999074,0.0014345532],"genre_scores_gemma":[0.000008878442,0.978858,0.00034374997,0.0023761,0.0023532654,0.004763123,0.000028868824,0.0002543001,0.011013749],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9905314,0.002685568,0.0007633672,0.002235885,0.001920088,0.0018637197],"domain_scores_gemma":[0.96683556,0.03021736,0.0002676874,0.0015504843,0.00085489545,0.00027400354],"candidate_categories":["metaresearch","metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0062473714,0.0007378309,0.0016900925,0.0007575384,0.0014842836,0.0004554131,0.002054053,0.0005630425,0.00080259884],"category_scores_gemma":[0.019649947,0.0005869004,0.0008924863,0.0019901895,0.0011489566,0.00044298434,0.00066247303,0.0015676472,0.0017918337],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023654338,0.0001991481,0.0000032234843,0.0008905139,0.0006849285,0.000017618026,0.00021763242,3.6494107e-8,0.000056827834,0.0003923621,0.5224884,0.47481278],"study_design_scores_gemma":[0.00070016587,0.0013592765,0.0000016895879,0.0010647135,0.000120847224,0.000038231297,0.000023403198,0.000075753385,0.00039867664,0.0019349098,0.99370927,0.00057305326],"about_ca_topic_score_codex":0.00022555079,"about_ca_topic_score_gemma":0.00005639384,"teacher_disagreement_score":0.4742397,"about_ca_system_score_codex":0.00024067717,"about_ca_system_score_gemma":0.0012717879,"threshold_uncertainty_score":0.99981564},"labels":[],"label_agreement":null},{"id":"W2891257593","doi":"10.1186/s13195-018-0419-2","title":"Clinical dementia severity associated with ventricular size is differentially moderated by cognitive reserve in men and women","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Baycrest Hospital; University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"University of Toronto; Alzheimer Society; Sunnybrook Foundation; Canadian Institutes of Health Research; Sunnybrook Research Institute","keywords":"Geriatric psychiatry; Cognitive reserve; Dementia; Neurology; Cognitive aging; Medicine; Cognition; Cognitive decline; Clinical psychology; Psychology; Psychiatry; Internal medicine; Cognitive impairment","score_opus":0.08189131204225747,"score_gpt":0.4117182999007879,"score_spread":0.32982698785853043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891257593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899104,0.00420504,0.000034128076,0.0014461899,0.000023469745,0.0020014169,0.000046296584,0.000045688,0.0022873746],"genre_scores_gemma":[0.9956255,0.0019505621,0.000035710556,0.00079471007,0.000099226905,0.00034314307,0.00008171752,0.00005406643,0.0010153494],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99402434,0.0016839036,0.000503363,0.0008408133,0.0016375817,0.001309986],"domain_scores_gemma":[0.99642956,0.0009686508,0.00009352099,0.0003414343,0.0016020704,0.00056478],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004067772,0.00029051866,0.0005683639,0.00026544128,0.00033583614,0.00016053066,0.00024036407,0.0002149187,0.0024381424],"category_scores_gemma":[0.0006553571,0.00021982938,0.00008128398,0.0010264623,0.0010966313,0.0002176727,0.00021911449,0.00096763956,0.000062683546],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009379726,0.0028671715,0.9353249,0.000014049588,0.007180942,0.00021398171,0.002399128,1.6949947e-8,0.001854204,0.0000034383359,0.009826261,0.030936174],"study_design_scores_gemma":[0.018730717,0.008949918,0.95481235,0.00023159591,0.00022032404,0.000012453904,0.0012520014,0.0005674046,0.012015559,0.00027844877,0.0025850958,0.00034413743],"about_ca_topic_score_codex":0.001248869,"about_ca_topic_score_gemma":0.00024127302,"teacher_disagreement_score":0.030592036,"about_ca_system_score_codex":0.00012529682,"about_ca_system_score_gemma":0.0005711297,"threshold_uncertainty_score":0.99847376},"labels":[],"label_agreement":null},{"id":"W2892727357","doi":"10.1186/s13195-018-0427-2","title":"Adaptive crossover designs for assessment of symptomatic treatments targeting behaviour in neurodegenerative disease: a phase 2 clinical trial of intranasal oxytocin for frontotemporal dementia (FOXY)","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Neuroendocrine regulation and behavior","field":"Psychology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Parkwood Institute; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; National Institute of Neurological Disorders and Stroke; Weston Brain Institute","keywords":"Oxytocin; Medicine; Apathy; Crossover study; Clinical trial; Neurology; Dosing; Frontotemporal dementia; Dementia; Disease; Internal medicine; Psychiatry; Placebo; Pathology","score_opus":0.4807146225287585,"score_gpt":0.5929440130875983,"score_spread":0.11222939055883974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2892727357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98629045,0.00093086244,0.00418958,0.0003396051,0.00051064015,0.0074112997,0.00026305232,0.00002033174,0.00004418545],"genre_scores_gemma":[0.9931499,0.00003600834,0.003991505,0.000041233307,0.0003306728,0.0021053758,0.00008192339,0.000057459652,0.00020593639],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99563533,0.0014458029,0.0011289231,0.0006190369,0.00054673984,0.0006241741],"domain_scores_gemma":[0.9974887,0.0009013628,0.00035359612,0.00044875243,0.00060721964,0.00020042023],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015500982,0.00024432415,0.0005793601,0.00027753407,0.00015767678,0.000031977204,0.00032250056,0.000085224936,0.00039299842],"category_scores_gemma":[0.00009279802,0.00020930731,0.00033451882,0.00028763324,0.00049380335,0.00014418969,0.000046236044,0.00021953284,0.000003180736],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.5256445,0.051112782,0.18506269,0.000055718236,0.007876568,0.000082243925,0.003921605,0.000023576531,0.026802722,0.003670122,0.023122005,0.17262551],"study_design_scores_gemma":[0.5469539,0.0821526,0.32653424,0.00012216046,0.0015760466,0.0000027429721,0.0008987425,0.0075162016,0.029381923,0.0012903836,0.0027713312,0.0007997318],"about_ca_topic_score_codex":0.00016771707,"about_ca_topic_score_gemma":0.0000510095,"teacher_disagreement_score":0.17182578,"about_ca_system_score_codex":0.000041661842,"about_ca_system_score_gemma":0.00034672164,"threshold_uncertainty_score":0.8535304},"labels":[],"label_agreement":null},{"id":"W2898540928","doi":"10.1186/s13195-018-0434-3","title":"Functional connectivity in cognitive control networks mitigates the impact of white matter lesions in the elderly","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Deutsche Forschungsgemeinschaft","keywords":"Default mode network; Cognition; Functional magnetic resonance imaging; Hyperintensity; Dementia; White matter; Psychology; Neuroscience; Executive functions; Working memory; Effects of sleep deprivation on cognitive performance; Cognitive decline; Resting state fMRI; Audiology; Magnetic resonance imaging; Medicine; Internal medicine","score_opus":0.16663806969332845,"score_gpt":0.3995296733978153,"score_spread":0.23289160370448686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898540928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97830516,0.0013934558,0.00020835632,0.016685646,0.00013925234,0.0013619391,0.00003971269,0.00001602303,0.0018504562],"genre_scores_gemma":[0.99654937,0.00016007962,0.0000026331675,0.0026093244,0.0002542713,0.00034829855,0.0000022228453,0.000021422087,0.000052368483],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9946987,0.003030021,0.00027773398,0.0005257779,0.0007950322,0.00067271607],"domain_scores_gemma":[0.96617514,0.03291302,0.000081245016,0.00040289242,0.0003751378,0.000052584997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003225206,0.00020819019,0.0002691016,0.0002737885,0.00081407675,0.00007692853,0.00050516916,0.00008649486,0.00067059],"category_scores_gemma":[0.0026231532,0.000111817986,0.00015775445,0.001427498,0.0018521236,0.00026164003,0.00013313293,0.00088194327,0.00008664816],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008722861,0.002489487,0.8180201,0.000006681603,0.0011938849,0.00006135936,0.015775602,0.0021149674,0.031065889,0.0018115242,0.08220206,0.036535602],"study_design_scores_gemma":[0.0021853433,0.0017227106,0.98483104,0.00003804434,0.000012797482,0.000018354032,0.0010244095,0.0019180917,0.0046449327,0.0030679537,0.0003736101,0.0001627298],"about_ca_topic_score_codex":0.0011960417,"about_ca_topic_score_gemma":0.0007919134,"teacher_disagreement_score":0.16681094,"about_ca_system_score_codex":0.00005415093,"about_ca_system_score_gemma":0.0001739356,"threshold_uncertainty_score":0.73424894},"labels":[],"label_agreement":null},{"id":"W2901859541","doi":"10.1186/s13195-018-0443-2","title":"Insights into globalization: comparison of patient characteristics and disease progression among geographic regions in a multinational Alzheimer’s disease clinical program","year":2018,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"H. Lundbeck A/S; Cognoptix; University of Rochester; Arizona Department of Health Services; Pfizer; Genentech; AstraZeneca; National Institute on Aging; Eli Lilly and Company; National Institute of General Medical Sciences; Abbott Laboratories","keywords":"Medicine; Clinical trial; Clinical Dementia Rating; Adverse effect; Demography; Disease; Internal medicine; Alzheimer's disease","score_opus":0.106550031234523,"score_gpt":0.4782294936769528,"score_spread":0.3716794624424298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901859541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98040783,0.01404339,0.000044176268,0.0015009156,0.00008338639,0.0036589894,0.0000108390905,0.000051054656,0.00019944056],"genre_scores_gemma":[0.9962314,0.0019973407,0.00047884366,0.00014662421,0.0001867482,0.0006836805,0.00023235133,0.000030824212,0.000012192162],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99552125,0.0009112639,0.0007828512,0.00061578094,0.0016321274,0.00053672487],"domain_scores_gemma":[0.99639297,0.00027456568,0.00017865107,0.0004495861,0.0016141275,0.0010900984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008939167,0.00022264553,0.0004177697,0.0005885068,0.00030278752,0.000080092075,0.00020873734,0.000110519715,0.00010884239],"category_scores_gemma":[0.0005715558,0.00017519465,0.00013235537,0.0010307069,0.0022002372,0.00021534046,0.00022774744,0.0004781194,0.000014395629],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026148278,0.0042205187,0.7326634,0.000027837257,0.00031973576,0.00004103794,0.0005697884,1.0491342e-7,0.000046074656,0.00040516353,0.00034869762,0.25874284],"study_design_scores_gemma":[0.0025935536,0.0034423575,0.9811907,0.00037445416,0.00015149519,8.9958536e-7,0.00023387808,0.0033800146,0.0003005436,0.0010963979,0.007067635,0.00016807135],"about_ca_topic_score_codex":0.000093564806,"about_ca_topic_score_gemma":0.00004390016,"teacher_disagreement_score":0.25857475,"about_ca_system_score_codex":0.000027946793,"about_ca_system_score_gemma":0.00054207456,"threshold_uncertainty_score":0.8106866},"labels":[],"label_agreement":null},{"id":"W2904986521","doi":"10.1186/s13195-018-0446-z","title":"Correction to: The Toronto cognitive assessment (TorCA): normative data and validation to detect amnestic mild cognitive impairment","year":2018,"lang":"en","type":"erratum","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Mental Health Research Canada; Institute for Work & Health; Toronto Rehabilitation Institute; Centre for Addiction and Mental Health; Sunnybrook Health Science Centre; St. Michael's Hospital; Toronto Dementia Research Alliance; Parkwood Institute; Lawson Health Research Institute; Sunnybrook Hospital; Health Sciences Centre; University Health Network; Occupational Cancer Research Centre; Toronto Western Hospital; Dalhousie University; University of Toronto; Baycrest Hospital","funders":"","keywords":"Normative; Cognitive impairment; Cognition; Psychology; Cognitive psychology; Political science; Psychiatry; Law","score_opus":0.11757529291375364,"score_gpt":0.4574951434003795,"score_spread":0.3399198504866259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2904986521","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16070276,0.16051483,0.027387477,0.05648206,0.08775124,0.17862967,0.010174875,0.0014155576,0.31694153],"genre_scores_gemma":[0.83585566,0.031658802,0.000845141,0.0068665682,0.0113783395,0.008962444,0.016406491,0.0005884254,0.0874381],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9895775,0.0023658448,0.0007195618,0.0018581693,0.0038697415,0.0016092062],"domain_scores_gemma":[0.9909966,0.0021451018,0.00021876825,0.0014128516,0.0041878666,0.0010388262],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.005933844,0.0007784939,0.0008903642,0.0006519714,0.0011577866,0.00060700544,0.0010513952,0.00036922924,0.0019614478],"category_scores_gemma":[0.0013909037,0.0005559695,0.00016681511,0.0011464066,0.00066632614,0.0006044454,0.0016158099,0.0023827988,0.00081725646],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003345308,0.0005329082,0.0011245747,0.000060690556,0.0033851336,0.000037252867,0.0026549888,1.4407007e-7,0.00010801625,0.0000024719275,0.81018937,0.17855915],"study_design_scores_gemma":[0.010041872,0.038403824,0.29863808,0.005530692,0.002768189,0.00017182485,0.016612764,0.0014190768,0.006962299,0.00015232034,0.6175054,0.0017936797],"about_ca_topic_score_codex":0.0033814493,"about_ca_topic_score_gemma":0.002387499,"teacher_disagreement_score":0.6751529,"about_ca_system_score_codex":0.0006561007,"about_ca_system_score_gemma":0.0019561753,"threshold_uncertainty_score":0.9999607},"labels":[],"label_agreement":null},{"id":"W2914535606","doi":"10.1186/s13195-018-0453-0","title":"Alcohol use and dementia: a systematic scoping review","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alcoholism and Thiamine Deficiency","field":"Medicine","cited_by":446,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; Sunnybrook Health Science Centre; Mental Health Research Canada; Canada Research Chairs; University of Toronto","funders":"","keywords":"Dementia; PsycINFO; Medicine; Systematic review; Cognition; Geriatric psychiatry; MEDLINE; Psychiatry; Internal medicine; Disease","score_opus":0.25295910827682316,"score_gpt":0.44778734675815873,"score_spread":0.19482823848133557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914535606","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.25746343,0.7336645,0.000008913445,0.0009878208,0.00008068336,0.0064785657,0.0000018737808,0.000046335565,0.0012678368],"genre_scores_gemma":[0.8204026,0.1773053,0.00013624143,0.0013858945,0.000060494815,0.00027866135,0.000011244214,0.00004038748,0.00037913283],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9973887,0.00043153012,0.0003881155,0.0004004923,0.0008793595,0.00051178964],"domain_scores_gemma":[0.9982171,0.00048160425,0.000071281145,0.0007317783,0.0003064207,0.00019178772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002377077,0.0001732106,0.0006305096,0.00019320991,0.00012958227,0.00009128662,0.00016968195,0.000069024594,0.00041389218],"category_scores_gemma":[0.0002702483,0.000117398,0.00009247249,0.00046576938,0.00012414805,0.00026739624,0.000098905904,0.00033775126,0.00050582446],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016682781,0.0016610393,0.16795658,0.71600646,0.015162254,0.0006505147,0.00370061,0.0000014265271,0.034961272,0.0060180924,0.02147684,0.030736662],"study_design_scores_gemma":[0.012590151,0.004198337,0.025121756,0.9396393,0.0026892067,0.0007229575,0.00047657941,0.00031169134,0.007737017,0.0002113256,0.0051711276,0.0011305746],"about_ca_topic_score_codex":0.00007793336,"about_ca_topic_score_gemma":0.000003352726,"teacher_disagreement_score":0.5629392,"about_ca_system_score_codex":0.000014685687,"about_ca_system_score_gemma":0.00014639097,"threshold_uncertainty_score":0.65015185},"labels":[],"label_agreement":null},{"id":"W2915228783","doi":"10.1186/s13195-019-0471-6","title":"Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer’s disease","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; Avid Radiopharmaceuticals; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Pfizer; Novartis Pharmaceuticals Corporation; Eisai; U.S. Department of Defense; Meso Scale Diagnostics; Servier; BioClinica; Bristol-Myers Squibb; Eli Lilly and Company; Biogen","keywords":"Geriatric psychiatry; Neurology; Neuroscience; Disease; Medicine; Amyloid (mycology); Alzheimer's disease; Amyloid β; Psychology; Pathology; Psychiatry","score_opus":0.06985980900164747,"score_gpt":0.35571267603647355,"score_spread":0.2858528670348261,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2915228783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851911,0.008565987,0.000004941232,0.0033705742,0.000058097798,0.0023173818,0.000024444527,0.000041588628,0.00042590188],"genre_scores_gemma":[0.99758023,0.0010361696,0.00003467159,0.000493375,0.0001136018,0.00029605604,0.00012546394,0.000047691115,0.00027273913],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99574196,0.00058385025,0.00032328954,0.00066736975,0.0017661244,0.00091741607],"domain_scores_gemma":[0.9978509,0.00049417955,0.00006416338,0.00031557836,0.00046786095,0.0008073312],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0017404205,0.0002735317,0.00043100555,0.00044114882,0.00019278817,0.00012856681,0.000120217,0.000117217234,0.001192424],"category_scores_gemma":[0.000170415,0.0002006209,0.00006294642,0.0005596658,0.000640695,0.00025180032,0.00016266305,0.0008782591,0.00007326197],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0068532135,0.0009920996,0.97978264,0.000015424188,0.0010251452,0.0002193479,0.00026730556,5.0897535e-7,0.0014422656,0.00005242598,0.0008170564,0.008532547],"study_design_scores_gemma":[0.009837657,0.0031804573,0.98365766,0.00016652294,0.0001469868,0.000018235627,0.0005279917,0.00022744526,0.0005045689,0.00012108366,0.0013842605,0.00022710655],"about_ca_topic_score_codex":0.00019157019,"about_ca_topic_score_gemma":0.00013197272,"teacher_disagreement_score":0.0123891495,"about_ca_system_score_codex":0.00007343947,"about_ca_system_score_gemma":0.0006502162,"threshold_uncertainty_score":0.99972063},"labels":[],"label_agreement":null},{"id":"W2916649021","doi":"10.1186/s13195-018-0461-0","title":"CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Traumatic Brain Injury Research","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; International Collaboration On Repair Discoveries; University of British Columbia","funders":"Weston Brain Institute; Consortium canadien en neurodégénérescence associée au vieillissement; University of British Columbia; Canadian Institutes of Health Research; National Institute for Health and Care Research; National Institutes of Health","keywords":"Traumatic brain injury; Medicine; Concussion; Neurology; Morris water navigation task; White matter; Elevated plus maze; Motor coordination; Righting reflex; Anesthesia; Poison control; Internal medicine; Pediatrics; Anxiety; Injury prevention; Psychiatry; Reflex; Hippocampus; Magnetic resonance imaging","score_opus":0.23800656698899655,"score_gpt":0.42900222441377994,"score_spread":0.1909956574247834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916649021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9757271,0.015072916,0.0000011814849,0.0057203704,0.000089566944,0.0023519876,0.000011008303,0.00007002171,0.00095589523],"genre_scores_gemma":[0.9956541,0.0027552114,0.00030768424,0.00054082595,0.00012947641,0.00011843198,0.00002250674,0.00007147483,0.0004002552],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.995284,0.0012641542,0.0004912331,0.0008845569,0.0010700098,0.0010059994],"domain_scores_gemma":[0.99732965,0.0012908089,0.000072963776,0.00064129167,0.00030373613,0.00036157196],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0027899272,0.00032964235,0.00064007746,0.00060565234,0.0001722238,0.00012581002,0.00033140514,0.00025266077,0.00057615264],"category_scores_gemma":[0.00038005007,0.00025853197,0.00006320695,0.0010745052,0.00085517706,0.0002705778,0.0002243441,0.0017521274,0.00013564782],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008261118,0.0016285401,0.18319593,0.00034585473,0.0010887022,0.0005199034,0.013994773,0.0000017591257,0.2988273,0.0013447558,0.00275424,0.4880371],"study_design_scores_gemma":[0.0063595693,0.009213311,0.96573937,0.00046709317,0.00007303358,0.00032453085,0.0015688189,0.00033288402,0.013062306,0.00070792617,0.0016146041,0.00053656334],"about_ca_topic_score_codex":0.0005273944,"about_ca_topic_score_gemma":0.00007379556,"teacher_disagreement_score":0.7825434,"about_ca_system_score_codex":0.00008618078,"about_ca_system_score_gemma":0.00035931132,"threshold_uncertainty_score":0.9999867},"labels":[],"label_agreement":null},{"id":"W2917699212","doi":"10.1186/s13195-018-0462-z","title":"Data-driven prognostic features of cognitive trajectories in patients with amnestic mild cognitive impairments","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Ministry of Public Safety and Security; National Fire Agency; National Research Foundation of Korea; Centers for Disease Control and Prevention; Ministry of Science, ICT and Future Planning; National Research Foundation","keywords":"Cognition; Neurology; Geriatric psychiatry; Medicine; Cognitive aging; Psychology; Clinical psychology; Psychiatry","score_opus":0.07397402745561148,"score_gpt":0.3893227462204683,"score_spread":0.3153487187648568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2917699212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98865986,0.0022066662,0.000010037022,0.00015304572,0.000060703424,0.0066097574,0.00031783112,0.0000337622,0.0019483117],"genre_scores_gemma":[0.9974962,0.00032720066,0.000081994796,0.00012961062,0.0000576142,0.00030045936,0.0012604574,0.00006905493,0.00027745005],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9946704,0.0006401805,0.00041376214,0.0008662469,0.0023642657,0.0010451608],"domain_scores_gemma":[0.9955449,0.0015209881,0.00011458996,0.000610742,0.0019202247,0.00028852993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011147944,0.00033478075,0.00060100155,0.0007176776,0.0001139708,0.00006523387,0.00048047196,0.00012632308,0.000714768],"category_scores_gemma":[0.00048225067,0.00024248977,0.00007822339,0.0012834702,0.0006491985,0.000439616,0.00028053427,0.00087130343,0.00015403892],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011930249,0.0031882597,0.95761734,0.000076820674,0.001849099,0.000060933293,0.0010774068,4.3107212e-7,0.00019048035,0.000012235228,0.00024083506,0.02375593],"study_design_scores_gemma":[0.017265955,0.010331221,0.9665268,0.0011622937,0.00022641038,0.0000067707997,0.0017240263,0.000030229141,0.0023461569,0.000042068186,0.00009006507,0.0002480085],"about_ca_topic_score_codex":0.00026935915,"about_ca_topic_score_gemma":0.000072722425,"teacher_disagreement_score":0.023507921,"about_ca_system_score_codex":0.000054650438,"about_ca_system_score_gemma":0.0006103907,"threshold_uncertainty_score":0.9888446},"labels":[],"label_agreement":null},{"id":"W2921604361","doi":"10.1186/s13195-019-0476-1","title":"Lewy Body Dementia Association’s Research Centers of Excellence Program: Inaugural Meeting Proceedings","year":2019,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; Avid Radiopharmaceuticals; Parkinsonfonden; Johns Hopkins University; University of California, San Diego; AstraZeneca; Genentech; Health Resources and Services Administration; University of Southern California; Eisai; National Institute for Health and Care Research; Mayo Clinic; TauRx Pharmaceuticals; Administration for Community Living; Scheme for Promotion of Academic and Research Collaboration; Little Family Foundation; Gordon and Marilyn Macklin Foundation; Prothena; Acorda Therapeutics; Ionis Pharmaceuticals; Michael J. Fox Foundation for Parkinson's Research; Parkinson's Foundation; H. Lundbeck A/S; Lewy Body Dementia Association; National Institute of Neurological Disorders and Stroke; Sunovion; Allergan; F. Hoffmann-La Roche; Rush University; Demensförbundet; Georgetown University; Georgia Research Alliance; Grifols; Tau Consortium; Emerald Foundation; CurePSP; University of Pennsylvania; Bristol-Myers Squibb; Teva Pharmaceutical Industries; CHDI Foundation; International Parkinson and Movement Disorder Society; National Ataxia Foundation; Biogen; U.S. Department of Defense; Eli Lilly and Company; BrightFocus Foundation; Sanofi; Alzheimer's Association; National Institutes of Health; Association for Frontotemporal Degeneration; Janssen Pharmaceuticals; Parkinson Vereniging","keywords":"Dementia with Lewy bodies; Lewy body; Excellence; Dementia; Clinical trial; Medicine; Gerontology; Family medicine; Disease; Political science; Pathology","score_opus":0.7999105234205437,"score_gpt":0.6023940974326253,"score_spread":0.1975164259879184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921604361","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00036035167,0.9777219,0.0000038612316,0.0039568013,0.0005875615,0.008212438,0.0002174826,0.00007766364,0.008861913],"genre_scores_gemma":[0.0008637919,0.9933505,0.0006574357,0.0002265128,0.0006904282,0.0023136914,0.00012356877,0.00018616595,0.0015878985],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98498714,0.002961448,0.006775269,0.0016483027,0.0014175907,0.0022102771],"domain_scores_gemma":[0.98667,0.0055448203,0.0046967003,0.0010938366,0.0016045391,0.0003900865],"candidate_categories":["metaresearch","metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.11481993,0.00057217595,0.003920662,0.002304371,0.0006421596,0.0004869806,0.0021013233,0.00079912954,0.00064669456],"category_scores_gemma":[0.0057545984,0.00062538026,0.0007221111,0.0019527244,0.00035590574,0.0007365904,0.00046040388,0.0022945167,0.004243104],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012179254,0.0018603544,0.015411715,0.036871497,0.01525809,0.000005569501,0.006856428,0.0000027633535,0.000006118651,0.02823512,0.42088497,0.4744856],"study_design_scores_gemma":[0.00057321007,0.00050544,0.00014301564,0.004238871,0.00009043948,0.0000023877342,0.0006998748,0.00008241759,0.0000046347855,0.0009772303,0.99217945,0.0005030184],"about_ca_topic_score_codex":0.0024289517,"about_ca_topic_score_gemma":0.000026625425,"teacher_disagreement_score":0.5712945,"about_ca_system_score_codex":0.0018958665,"about_ca_system_score_gemma":0.0014072726,"threshold_uncertainty_score":0.9996197},"labels":[],"label_agreement":null},{"id":"W2922462803","doi":"10.1186/s13195-019-0467-2","title":"Evaluation of the efficacy, safety and tolerability of orally administered BI 409306, a novel phosphodiesterase type 9 inhibitor, in two randomised controlled phase II studies in patients with prodromal and mild Alzheimer’s disease","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"Cilag; Merck Sharp and Dohme; Novartis Pharma; Merz Pharmaceuticals; AstraZeneca; Eli Lilly and Company; Boehringer Ingelheim","keywords":"Tolerability; Medicine; Clinical Dementia Rating; Internal medicine; Clinical endpoint; Adverse effect; Placebo; Dementia; Clinical trial; Disease","score_opus":0.1071811292687882,"score_gpt":0.4065201067674525,"score_spread":0.2993389774986643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922462803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9808602,0.014484548,0.0000016496455,0.00016317875,0.000099834,0.004344498,0.000020998992,0.000002700271,0.000022419197],"genre_scores_gemma":[0.99929976,0.0004268104,0.00003250702,0.000040290168,0.000018624316,0.000108627624,0.000039660667,0.000015040821,0.000018651439],"study_design_codex":"randomized_trial","study_design_gemma":"observational","domain_scores_codex":[0.9975069,0.0007550946,0.00047811551,0.00039606987,0.0006479513,0.00021584201],"domain_scores_gemma":[0.99825156,0.00016234975,0.00017657476,0.00040153338,0.0009317896,0.00007620489],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025014095,0.00017552105,0.00042884544,0.00010166653,0.000085491134,0.000012876521,0.0001131266,0.000059700087,0.000013507224],"category_scores_gemma":[0.00035769754,0.00010830845,0.000057275476,0.00026336304,0.00041495392,0.000020644648,0.00013088167,0.00012973565,2.558845e-7],"study_design_candidate":"randomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.5664451,0.0053595076,0.29210848,0.000066335844,0.0024649103,0.00000109015,0.002899097,0.0004983609,0.097423285,0.00002417515,0.00006377748,0.032645863],"study_design_scores_gemma":[0.43059927,0.004642409,0.5138961,0.00021224386,0.00029537504,6.8580704e-7,0.00023194677,0.0012986729,0.048282728,0.000046028774,0.0002299241,0.0002646158],"about_ca_topic_score_codex":0.000054553446,"about_ca_topic_score_gemma":0.00013810424,"teacher_disagreement_score":0.22178765,"about_ca_system_score_codex":0.000023007691,"about_ca_system_score_gemma":0.00034695448,"threshold_uncertainty_score":0.44166905},"labels":[],"label_agreement":null},{"id":"W2922917123","doi":"10.1186/s13195-019-0474-3","title":"Brief cognitive screening instruments for early detection of Alzheimer’s disease: a systematic review","year":2019,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":216,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Instituut Born-Bunge; Vlaamse regering; Universiteit Antwerpen; Universitaire Stichting; Agentschap Innoveren en Ondernemen","keywords":"Cognitive test; Medicine; Cognition; Population; Psychometric testing; Psychometrics; Memory clinic; Montreal Cognitive Assessment; Test (biology); Cognitive impairment; Psychology; Medical physics; Clinical psychology; Psychiatry","score_opus":0.2561106692417371,"score_gpt":0.4798998130176027,"score_spread":0.22378914377586562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922917123","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000052751147,0.95624334,0.00021722866,0.000080608464,0.00011515295,0.04260361,0.00027013005,0.000055021053,0.0003621919],"genre_scores_gemma":[0.0017749141,0.9863985,0.00006314136,0.00020158093,0.00017608414,0.009968756,0.0005932785,0.00022311081,0.00060062617],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9905798,0.0023167846,0.0017466797,0.0011459291,0.002907318,0.0013035083],"domain_scores_gemma":[0.99343765,0.0015161423,0.00076840125,0.0011264163,0.0025014484,0.0006499397],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004918558,0.00076801266,0.004518536,0.0011428398,0.0002750121,0.000116730684,0.00061786483,0.0003250483,0.00029941148],"category_scores_gemma":[0.0010693314,0.00056652876,0.0018048958,0.0015488381,0.0003960487,0.00026686492,0.00025155535,0.0012338115,0.00027339705],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043169255,0.00029772244,0.000048023678,0.42512852,0.010710164,0.000013335181,0.000029099807,2.4598978e-9,0.000005971086,0.000007976114,0.00014447421,0.563183],"study_design_scores_gemma":[0.0030696448,0.0030097072,0.00030587794,0.8372672,0.033297002,0.000039082603,0.000060853647,0.000009834886,0.00022498074,0.000023067187,0.1221355,0.00055722793],"about_ca_topic_score_codex":0.00007296926,"about_ca_topic_score_gemma":0.00000203864,"teacher_disagreement_score":0.56262577,"about_ca_system_score_codex":0.00009724634,"about_ca_system_score_gemma":0.0013610855,"threshold_uncertainty_score":0.9996786},"labels":[],"label_agreement":null},{"id":"W2943109906","doi":"10.1186/s13195-019-0484-1","title":"Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)—study protocol for a randomized controlled trial","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"BioTechMed-Graz; Center for Stroke Research Berlin; Freie Universität Berlin; Humboldt-Universität zu Berlin; Deutsche Forschungsgemeinschaft; Deutsches Zentrum für Neurodegenerative Erkrankungen; Austrian Science Fund; Berlin Institute of Health; Bundesministerium für Bildung und Forschung; McGill University; Bundesministerium für Wissenschaft, Forschung und Wirtschaft; Karl-Franzens-Universität Graz","keywords":"Medicine; Cognitive decline; Dementia; Neurocognitive; Randomized controlled trial; Population; Placebo; Neuropsychology; Cognition; Gerontology; Physical therapy; Disease; Psychiatry; Internal medicine; Environmental health; Alternative medicine","score_opus":0.025045742387968098,"score_gpt":0.39193779902023934,"score_spread":0.36689205663227126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943109906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6124618,0.00015757623,0.00008124007,0.00003999246,0.000011668328,0.38716468,0.000014396976,0.0000025976192,0.000066029985],"genre_scores_gemma":[0.5959321,0.000049994003,0.000042124502,0.000025964937,0.000046625468,0.40379712,0.000074776515,0.000013123612,0.000018113784],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9980747,0.0007435078,0.00031808458,0.00037530644,0.0002640175,0.00022438884],"domain_scores_gemma":[0.99831307,0.0009861586,0.00013384888,0.00014375185,0.00037540958,0.00004778899],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014472648,0.00015445577,0.0004979848,0.00016192171,0.00005410281,0.000019022125,0.00008271845,0.000062606916,0.000019151896],"category_scores_gemma":[0.00024598325,0.000103037484,0.00008236254,0.00020311476,0.0001415141,0.0000083576715,0.000032192762,0.00008447515,0.0000016444042],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9415852,0.0016588382,0.00050131977,0.000024672177,0.0011655055,6.833241e-7,0.00037390043,3.1227844e-7,0.051095877,0.000019597866,0.000016389557,0.0035576925],"study_design_scores_gemma":[0.772265,0.005131864,0.0028351848,0.00005627396,0.00009339584,3.4585653e-7,0.00037007593,0.00004088333,0.21901597,0.00004179505,0.00005503579,0.00009417982],"about_ca_topic_score_codex":0.000089721325,"about_ca_topic_score_gemma":0.00006384828,"teacher_disagreement_score":0.16932021,"about_ca_system_score_codex":0.0000040122504,"about_ca_system_score_gemma":0.00008859194,"threshold_uncertainty_score":0.42017466},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"randomized_trial","genre":"protocol","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"randomized_trial","genre":"protocol","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"agree"},{"id":"W2947609180","doi":"10.1186/s13195-019-0497-9","title":"ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; Providence Health Care Research Institute; Providence Health Care; University of British Columbia","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Michael Smith Health Research BC; Consortium canadien en neurodégénérescence associée au vieillissement; BrightFocus Foundation","keywords":"Cerebral amyloid angiopathy; Astrogliosis; Neuroinflammation; Senile plaques; Neurodegeneration; Pathology; Medicine; Amyloid (mycology); Endocrinology; Internal medicine; Inflammation; Alzheimer's disease; Dementia; Disease; Central nervous system","score_opus":0.03935988066460991,"score_gpt":0.33427093256382934,"score_spread":0.2949110518992194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947609180","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9599292,0.03650435,0.000017101493,0.0005601424,0.0000485812,0.0022649847,0.000088338245,0.000114306065,0.0004729945],"genre_scores_gemma":[0.995685,0.0031373862,0.0003013727,0.00020432788,0.00011451976,0.00024538298,0.00018808151,0.00009168037,0.000032264797],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9928442,0.0015360246,0.000621858,0.001233317,0.0018655839,0.0018989971],"domain_scores_gemma":[0.9960753,0.0011931878,0.00011799539,0.00067015854,0.0004970675,0.0014463085],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017301334,0.0005412321,0.0008758236,0.0006551831,0.00049819396,0.00022597313,0.00028525936,0.00031603142,0.0002555434],"category_scores_gemma":[0.00045173027,0.00046181708,0.00019765536,0.0010492284,0.000971182,0.0005127791,0.00030229733,0.001557092,0.00016844625],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011156413,0.006335505,0.91711503,0.000070327646,0.0059353076,0.0006600415,0.00048221915,0.0000020173234,0.035399817,0.0002369944,0.00042071022,0.022185601],"study_design_scores_gemma":[0.011132356,0.0052774143,0.96948355,0.00023443418,0.00048706192,0.00024228326,0.00064713176,0.0006818728,0.010906763,0.00029777468,0.00009994827,0.0005093845],"about_ca_topic_score_codex":0.0023340988,"about_ca_topic_score_gemma":0.00021715714,"teacher_disagreement_score":0.05236853,"about_ca_system_score_codex":0.00025557578,"about_ca_system_score_gemma":0.00068782154,"threshold_uncertainty_score":0.99978334},"labels":[],"label_agreement":null},{"id":"W2947609328","doi":"10.1186/s13195-019-0503-2","title":"Early recognition and treatment of neuropsychiatric symptoms to improve quality of life in early Alzheimer’s disease: protocol of the BEAT-IT study","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Alzheimer Nederland; Newfoundland and Labrador; ZonMw","keywords":"Medicine; Caregiver burden; Dementia; Psychological intervention; Disease; Quality of life (healthcare); Context (archaeology); Intervention (counseling); Alzheimer's disease; Cognition; Gerontology; Psychiatry; Internal medicine","score_opus":0.13964499597061406,"score_gpt":0.432322816604603,"score_spread":0.29267782063398895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947609328","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88755655,0.00081876386,9.594753e-7,0.00061927736,0.00003912796,0.11057941,0.000048653263,0.000008405625,0.00032885524],"genre_scores_gemma":[0.97440666,0.00012716287,0.000025045074,0.000069265916,0.000046113546,0.025162034,0.0000059874224,0.000032854743,0.0001248629],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.995202,0.0013617061,0.000787728,0.0005384051,0.0016013636,0.00050880376],"domain_scores_gemma":[0.9975206,0.00036138622,0.0002012078,0.0007872088,0.00079149654,0.00033806937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017147042,0.00022595302,0.0006025481,0.00053094915,0.00006236416,0.000026631073,0.00028175276,0.00006471394,0.00018401451],"category_scores_gemma":[0.00013234431,0.000146974,0.00017410074,0.0011960533,0.00025049984,0.00012867115,0.00014397093,0.00026678303,0.00002941055],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011108464,0.0053333915,0.89237195,0.00007495728,0.0011089174,0.000003534015,0.0019400787,4.335035e-7,0.009024694,0.0000095832265,0.000034738496,0.07898925],"study_design_scores_gemma":[0.010904499,0.02085266,0.95875525,0.00009695377,0.00014764832,4.2174537e-7,0.00055122294,0.000008721927,0.008273611,0.00009504869,0.00019332202,0.00012063666],"about_ca_topic_score_codex":0.002936374,"about_ca_topic_score_gemma":0.000053914395,"teacher_disagreement_score":0.08685013,"about_ca_system_score_codex":0.000033853445,"about_ca_system_score_gemma":0.00048587794,"threshold_uncertainty_score":0.5993425},"labels":[],"label_agreement":null},{"id":"W2948651404","doi":"10.1186/s13195-019-0508-x","title":"Upregulation of MIF as a defense mechanism and a biomarker of Alzheimer’s disease","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Macrophage Migration Inhibitory Factor","field":"Immunology and Microbiology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Downregulation and upregulation; Biomarker; Mechanism (biology); Disease; Alzheimer's disease; Medicine; Chemistry; Internal medicine; Gene; Biochemistry","score_opus":0.08054573646689787,"score_gpt":0.3511382838632003,"score_spread":0.2705925473963024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2948651404","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94419205,0.05380898,0.000036687026,0.00023899428,0.00020672614,0.0010442031,0.00005157262,0.000024911467,0.00039586273],"genre_scores_gemma":[0.9986358,0.00055397063,0.000072817245,0.00005198361,0.000014723509,0.000048612015,0.00007542067,0.000026785914,0.00051983376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979904,0.00073022326,0.0003758539,0.00036295445,0.00018969602,0.0003508675],"domain_scores_gemma":[0.99857295,0.00030584674,0.00014790805,0.0005340587,0.0003704038,0.00006880936],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00079905806,0.00016667217,0.00030142916,0.0003059635,0.00009973399,0.000013746498,0.0002047687,0.0001744392,0.0032361904],"category_scores_gemma":[0.0000645439,0.000141362,0.000109048415,0.0002934792,0.00041909277,0.00013479004,0.00010082687,0.00021577998,0.0003408894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001428419,0.0001780935,0.0023644108,0.000015027357,0.001104232,0.0000027068359,0.00096760876,9.811733e-7,0.9777378,0.005932227,0.0009043117,0.009364194],"study_design_scores_gemma":[0.0028734445,0.00072206033,0.027734667,0.000055654775,0.00011810793,0.000010285428,0.0003009671,0.000050106097,0.95236784,0.0048214346,0.010720006,0.00022545074],"about_ca_topic_score_codex":0.00027573574,"about_ca_topic_score_gemma":0.000007513583,"teacher_disagreement_score":0.054443788,"about_ca_system_score_codex":0.000009220925,"about_ca_system_score_gemma":0.00015880335,"threshold_uncertainty_score":0.997675},"labels":[],"label_agreement":null},{"id":"W2952579863","doi":"10.1186/s13195-019-0509-9","title":"Frailty effects on non-demented cognitive trajectories are moderated by sex and Alzheimer’s genetic risk","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Frailty in Older Adults","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Dalhousie University; Women and Children’s Health Research Institute; University of Alberta","funders":"National Institute on Aging; Canadian Institutes of Health Research; Dalhousie University; National Institutes of Health; Consortium canadien en neurodégénérescence associée au vieillissement; Canada Research Chairs; Dalhousie Medical Research Foundation","keywords":"Cognitive aging; Geriatric psychiatry; Cognition; Neurology; Medicine; Dementia; Alzheimer's disease; Psychology; Gerontology; Psychiatry; Internal medicine; Disease","score_opus":0.07483868021118371,"score_gpt":0.3714948634935794,"score_spread":0.2966561832823957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952579863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9586856,0.03382584,0.000054644544,0.0010779769,0.00019656314,0.004479571,0.00012768696,0.00013368283,0.0014184556],"genre_scores_gemma":[0.99175566,0.0054015005,0.00018081683,0.0009769256,0.00022022938,0.00035759012,0.00013007109,0.00013602083,0.0008411846],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9953241,0.00081587036,0.00038648985,0.0010086732,0.0014175307,0.0010473813],"domain_scores_gemma":[0.99647146,0.001546218,0.00013378517,0.00073085143,0.0006329199,0.0004847741],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007761084,0.00048646578,0.00068597693,0.000326598,0.0003312129,0.00012214959,0.00026256338,0.0002881978,0.0004445514],"category_scores_gemma":[0.00025283798,0.00040114272,0.00011861848,0.0006256781,0.0003765603,0.00016448705,0.000098992394,0.0013036549,0.00052123686],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007605225,0.0017995402,0.17708357,0.00016709637,0.018129695,0.00026886078,0.0069849147,0.000015076839,0.072747685,0.000017577553,0.061525594,0.6536552],"study_design_scores_gemma":[0.026284529,0.0126268,0.38406876,0.0011578111,0.0010408529,0.000048740563,0.0015249316,0.0029051963,0.5565654,0.0004073412,0.012275939,0.0010937033],"about_ca_topic_score_codex":0.0006785461,"about_ca_topic_score_gemma":0.00003234992,"teacher_disagreement_score":0.6525615,"about_ca_system_score_codex":0.000053765754,"about_ca_system_score_gemma":0.00018662118,"threshold_uncertainty_score":0.999844},"labels":[],"label_agreement":null},{"id":"W2953750178","doi":"10.1186/s13195-019-0512-1","title":"FDG-PET as an independent biomarker for Alzheimer’s biological diagnosis: a longitudinal study","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":161,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Servier; National Natural Science Foundation of China; Eisai; Genentech; IXICO; Fudan University; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Geriatric psychiatry; Biomarker; Neurology; Medicine; Internal medicine; Oncology; Psychiatry; Biology","score_opus":0.31726914723172805,"score_gpt":0.49155878926792473,"score_spread":0.17428964203619668,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953750178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9760222,0.008787299,0.000024440864,0.0015323437,0.00018539587,0.010765545,0.0000252728,0.000112088404,0.002545437],"genre_scores_gemma":[0.99239826,0.0014729643,0.00019173505,0.0005363076,0.00025589106,0.0043987087,0.00012302047,0.00008038233,0.0005427525],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9932366,0.0011442908,0.00050463754,0.0013225587,0.0022207631,0.00157115],"domain_scores_gemma":[0.996145,0.0008269952,0.00007824656,0.0010152168,0.0012162155,0.00071828783],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0047751293,0.00041104775,0.00062780955,0.00066069205,0.00038753467,0.00024011577,0.00067325,0.00016754605,0.005434314],"category_scores_gemma":[0.0002060831,0.0002951271,0.00029037474,0.00081192644,0.0003546569,0.00034945837,0.00029356437,0.00080548535,0.0013916913],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007212476,0.007879839,0.89159954,0.000013105835,0.005658474,0.0002917668,0.0005143326,1.8986857e-7,0.0032656768,0.00020923435,0.0031169162,0.080238484],"study_design_scores_gemma":[0.0118176155,0.033214144,0.92053735,0.000056474808,0.0003203209,0.000099130906,0.0029956885,0.00010343673,0.0073430245,0.000891739,0.022189358,0.00043173545],"about_ca_topic_score_codex":0.00055693346,"about_ca_topic_score_gemma":0.000054651624,"teacher_disagreement_score":0.079806745,"about_ca_system_score_codex":0.0000676068,"about_ca_system_score_gemma":0.0004549676,"threshold_uncertainty_score":0.9999501},"labels":[],"label_agreement":null},{"id":"W2955273706","doi":"10.1186/s13195-019-0511-2","title":"An experimental model of Braak’s pretangle proposal for the origin of Alzheimer’s disease: the role of locus coeruleus in early symptom development","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Institute of Neurosciences, Mental Health and Addiction; Canadian Institutes of Health Research; Strong","keywords":"Locus coeruleus; Tauopathy; Neuroscience; Serotonergic; Psychology; Alzheimer's disease; Cerebral cortex; Medicine; Disease; Neurodegeneration; Pathology; Internal medicine; Central nervous system; Serotonin","score_opus":0.08251033662228607,"score_gpt":0.39226591097052604,"score_spread":0.30975557434823997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2955273706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84587693,0.14742924,0.000017457047,0.00033453357,0.00003489675,0.0058935643,0.00010815449,0.000018125811,0.00028710152],"genre_scores_gemma":[0.9974138,0.00069921557,0.0006719251,0.000028462504,0.0000449046,0.00097263604,0.000058716094,0.00007206956,0.000038281378],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99563736,0.0003908666,0.00065816904,0.0005135721,0.0019821518,0.00081786443],"domain_scores_gemma":[0.9970391,0.00045823463,0.00018245098,0.0011967724,0.00073203066,0.0003914485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014540448,0.00030162983,0.0005695816,0.00029171573,0.00016596897,0.00003177674,0.00073734176,0.00011225356,0.00013699586],"category_scores_gemma":[0.000035343397,0.0001719628,0.00024040574,0.00051517034,0.0007218861,0.00024147867,0.00014028125,0.0003755837,0.00002137424],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06117272,0.025573371,0.42105836,0.0003302452,0.08114727,0.00005642207,0.02479046,0.0012813718,0.23708616,0.01725881,0.00074846344,0.12949637],"study_design_scores_gemma":[0.0117592905,0.0053969477,0.058813255,0.0003108244,0.0009078066,0.0000047600315,0.0028832552,0.021260545,0.8944781,0.0025679958,0.0011547316,0.00046248914],"about_ca_topic_score_codex":0.0006721532,"about_ca_topic_score_gemma":0.000029470822,"teacher_disagreement_score":0.65739197,"about_ca_system_score_codex":0.000076285294,"about_ca_system_score_gemma":0.0028808776,"threshold_uncertainty_score":0.701244},"labels":[],"label_agreement":null},{"id":"W2968364625","doi":"10.1186/s13195-019-0526-8","title":"Prediction of amyloid pathology in cognitively unimpaired individuals using voxel-wise analysis of longitudinal structural brain MRI","year":2019,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Servier; Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España; Eisai; Genentech; IXICO; Ministerio de Economía y Competitividad; H. Lundbeck A/S; Ministerio de Educación, Cultura y Deporte; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; European Regional Development Fund; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Alzheimer's Association","keywords":"Medicine; Voxel; Magnetic resonance imaging; Dementia; Pathology; Neurology; Neuroradiology; Neuroscience; Radiology; Disease; Psychology","score_opus":0.14058198015293205,"score_gpt":0.4146916262507664,"score_spread":0.27410964609783434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2968364625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994924,0.0021043308,0.000078964906,0.00045737348,0.00004659141,0.0016360984,0.00016052145,0.000016659596,0.0005754685],"genre_scores_gemma":[0.99890625,0.00037508842,0.0002378176,0.00007435322,0.00004745235,0.00004322453,0.00018484412,0.000028404493,0.00010255871],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9953808,0.0011337013,0.0006465737,0.0005414628,0.0015594033,0.00073803484],"domain_scores_gemma":[0.99744034,0.00062237255,0.0001745379,0.00044003458,0.0011428305,0.00017986911],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00311692,0.00021041677,0.00079298887,0.0026371703,0.00007513126,0.0000238209,0.00026022756,0.00016478557,0.0015340728],"category_scores_gemma":[0.0001621257,0.0001781761,0.00025862674,0.003454129,0.00055915536,0.00022026573,0.00014547039,0.00055605284,0.000014960829],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014017939,0.00038994156,0.8776706,0.00003484809,0.00500546,0.000039105882,0.0009918592,0.000032940305,0.10358833,0.000048885107,0.00006434785,0.010731926],"study_design_scores_gemma":[0.004490967,0.0023494414,0.95148593,0.00009725362,0.00062633556,0.000016468834,0.000855716,0.00307174,0.036625154,0.00017124697,0.00009373008,0.00011603686],"about_ca_topic_score_codex":0.0006020835,"about_ca_topic_score_gemma":0.000040115796,"teacher_disagreement_score":0.073815346,"about_ca_system_score_codex":0.000072433584,"about_ca_system_score_gemma":0.0003952204,"threshold_uncertainty_score":0.9993787},"labels":[],"label_agreement":null},{"id":"W3014449822","doi":"10.1186/s13195-020-00603-8","title":"Enhanced diagnostic accuracy for neurocognitive disorders: a revised cut-off approach for the Montreal Cognitive Assessment","year":2020,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Neurocognitive; Montreal Cognitive Assessment; Cognition; Psychology; Cognitive impairment; Clinical psychology; Psychiatry; Cognitive psychology","score_opus":0.13539296149589797,"score_gpt":0.4411611102664542,"score_spread":0.30576814877055625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014449822","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12929006,0.06881584,0.51365536,0.09451663,0.00039410673,0.1565306,0.0011848521,0.00077921915,0.03483335],"genre_scores_gemma":[0.9606849,0.013892872,0.0010197016,0.0036512394,0.00068427104,0.019249562,0.00044360393,0.00011797412,0.00025590378],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99510354,0.0006915565,0.0004698818,0.0010074963,0.0014102324,0.0013172696],"domain_scores_gemma":[0.9798178,0.017183421,0.00012490663,0.00038402082,0.001962141,0.0005277312],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018528436,0.0003914043,0.0005591781,0.00018866,0.00079682237,0.0002367098,0.0004656101,0.000118424745,0.0002858961],"category_scores_gemma":[0.0053259335,0.00026362613,0.00044838293,0.00080408144,0.0005312297,0.0002599217,0.00017722759,0.0008531128,0.00004224637],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011674987,0.0019578082,0.0019918843,0.00018574139,0.004347162,0.000013386681,0.0024621552,0.000003894404,0.0035929354,0.00016002644,0.010854182,0.96275586],"study_design_scores_gemma":[0.15070394,0.08130812,0.3035648,0.0011992696,0.0067549064,0.000036955153,0.043112338,0.09954124,0.10974764,0.004590219,0.19617237,0.003268216],"about_ca_topic_score_codex":0.00008985183,"about_ca_topic_score_gemma":0.000015756168,"teacher_disagreement_score":0.9594876,"about_ca_system_score_codex":0.00004613447,"about_ca_system_score_gemma":0.0006473995,"threshold_uncertainty_score":0.9999816},"labels":[],"label_agreement":null},{"id":"W3023832122","doi":"10.1186/s13195-020-00620-7","title":"The cholinergic system in subtypes of Alzheimer’s disease: an in vivo longitudinal MRI study","year":2020,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; University of California, San Diego; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; University of California, Los Angeles; National Institutes of Health; IXICO; Servier; Karolinska Institutet; Vetenskapsrådet; Eisai; Genentech; Stiftelsen för Strategisk Forskning; Northern California Institute for Research and Education; Stockholms Läns Landsting; Pfizer; Biogen; BioClinica; Alzheimer's Association; Åke Wiberg Stiftelse; F. Hoffmann-La Roche; Medpace; Demensförbundet; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Synarc; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Foundation for the National Institutes of Health","keywords":"Geriatric psychiatry; Neurology; Disease; Cholinergic; Medicine; Neuroscience; In vivo; Cholinergic system; Psychopharmacology; Alzheimer's disease; Pathology; Internal medicine; Psychology; Psychiatry; Biology","score_opus":0.23052843649407953,"score_gpt":0.4120035408333846,"score_spread":0.18147510433930505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3023832122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98517686,0.010698546,0.0000053936774,0.0020999499,0.00014024775,0.0015514926,0.000015091429,0.000041743835,0.000270649],"genre_scores_gemma":[0.99856144,0.00088447635,0.000009070228,0.000105355626,0.00019692465,0.0001874061,0.0000020719629,0.000028178063,0.000025069743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99507546,0.002235253,0.000491433,0.000645999,0.0010163877,0.0005354343],"domain_scores_gemma":[0.9985799,0.0003976168,0.00008891944,0.0005725765,0.00012351906,0.00023744821],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018634036,0.00018293667,0.00026252054,0.0002104086,0.0003152553,0.00012167938,0.0007924158,0.000056887806,0.000037059257],"category_scores_gemma":[0.00013621584,0.00012122354,0.00006833709,0.0013675197,0.00031206768,0.00033196397,0.00011679271,0.00048765127,0.00002505071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009172734,0.0046381094,0.12892053,0.00005622076,0.0004141899,0.0009634974,0.010851187,0.0060285307,0.8019493,0.013179432,0.0030930662,0.020733187],"study_design_scores_gemma":[0.0038413624,0.003143745,0.08097515,0.000077704535,0.000063411186,0.0000069500757,0.0029677006,0.02118005,0.88291645,0.0002765571,0.0040187393,0.00053218054],"about_ca_topic_score_codex":0.0003406384,"about_ca_topic_score_gemma":0.0003408059,"teacher_disagreement_score":0.08096712,"about_ca_system_score_codex":0.00002620986,"about_ca_system_score_gemma":0.00017100274,"threshold_uncertainty_score":0.49433523},"labels":[],"label_agreement":null},{"id":"W3026056964","doi":"10.1186/s13195-020-00621-6","title":"Longitudinal trajectories of Alzheimer’s ATN biomarkers in elderly persons without dementia","year":2020,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Key Research and Development Program of China; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Servier; National Natural Science Foundation of China; Eisai; Genentech; IXICO; Fudan University; Northern California Institute for Research and Education; University of California, San Diego; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; Synarc; University of Southern California; Medpace; Eli Lilly and Company; Bristol-Myers Squibb; Novartis Pharmaceuticals Corporation; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Biomarker; Dementia; Medicine; Cohort; Alzheimer's Disease Neuroimaging Initiative; Oncology; Alzheimer's disease; Neurology; Disease; Geriatric psychiatry; Internal medicine; Amyloid (mycology); Pathology; Psychiatry; Biology","score_opus":0.17683605627942978,"score_gpt":0.4148400300651585,"score_spread":0.23800397378572874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026056964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9443518,0.04100679,0.000085005406,0.0075006527,0.00006693443,0.0021434682,0.000018236777,0.00006276057,0.004764387],"genre_scores_gemma":[0.99709886,0.001649892,0.00045714792,0.0002989926,0.00015379245,0.00018573491,0.00003548897,0.00005841187,0.00006170595],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9953524,0.00057493214,0.00051550346,0.0006807976,0.0018218094,0.0010545731],"domain_scores_gemma":[0.99821234,0.00020704311,0.00008148639,0.00040380415,0.000573638,0.000521712],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016100219,0.00028709907,0.0005661977,0.00055652903,0.00016834307,0.00006719964,0.0003727968,0.00013040777,0.0018046593],"category_scores_gemma":[0.00015614371,0.0002435669,0.00022788161,0.0015723741,0.00069857173,0.00024137383,0.00013588002,0.000745809,0.00010221328],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00424632,0.00085412164,0.8464568,0.00005273799,0.010210798,0.00016019042,0.0028292718,7.0095865e-7,0.05589673,0.00011424855,0.004631918,0.074546136],"study_design_scores_gemma":[0.010877421,0.009691363,0.79023904,0.00020319385,0.0007448984,0.000029947721,0.004192332,0.000295926,0.16619955,0.00015230812,0.01687681,0.00049721065],"about_ca_topic_score_codex":0.00073923054,"about_ca_topic_score_gemma":0.00008513796,"teacher_disagreement_score":0.11030283,"about_ca_system_score_codex":0.00003399805,"about_ca_system_score_gemma":0.0005518537,"threshold_uncertainty_score":0.99910784},"labels":[],"label_agreement":null},{"id":"W3030424674","doi":"10.1186/s13195-020-00628-z","title":"APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease","year":2020,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; ZonMw; European Federation of Pharmaceutical Industries and Associations; Northern California Institute for Research and Education; F. Hoffmann-La Roche; University of Southern California; Pfizer; BioClinica; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; University of California, San Diego; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Apolipoprotein E; Cerebrospinal fluid; Dementia; Genotype; Alzheimer's disease; Amyloid (mycology); Disease; Proteomics; Pathophysiology; Neuroscience; Biology; Internal medicine; Psychology; Pathology; Medicine; Endocrinology; Biochemistry; Gene","score_opus":0.11769741733877766,"score_gpt":0.38729899544059115,"score_spread":0.2696015781018135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3030424674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5312677,0.4337798,0.000025397976,0.021477746,0.00015299258,0.010125348,0.00018648374,0.00036138497,0.0026231739],"genre_scores_gemma":[0.9904277,0.005522015,0.00029494468,0.0016486339,0.0006196348,0.0010550887,0.00018672369,0.00017330654,0.000071977236],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99236834,0.0008429934,0.0006248571,0.0013703678,0.0028573489,0.0019360954],"domain_scores_gemma":[0.9952263,0.00021543948,0.0000909865,0.0010490967,0.0005563741,0.002861801],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0009385413,0.0005959966,0.000730803,0.00057041174,0.0003980693,0.00018037729,0.0007567539,0.00024751207,0.0018884094],"category_scores_gemma":[0.00022099206,0.00048658316,0.00035538574,0.0013143674,0.0005378238,0.0003635422,0.0003228057,0.0016368248,0.0018166935],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.17705391,0.019529765,0.27942383,0.0005127687,0.14488927,0.026036676,0.006256736,0.00049636513,0.06825359,0.0028291855,0.09476006,0.17995782],"study_design_scores_gemma":[0.069841646,0.021173226,0.7012146,0.0009849541,0.0048523024,0.00009950341,0.0013112591,0.008457684,0.13143633,0.0049809567,0.051274795,0.0043727476],"about_ca_topic_score_codex":0.00046445557,"about_ca_topic_score_gemma":0.000019162873,"teacher_disagreement_score":0.45916,"about_ca_system_score_codex":0.00017005218,"about_ca_system_score_gemma":0.0018216975,"threshold_uncertainty_score":0.9997586},"labels":[],"label_agreement":null},{"id":"W3042078075","doi":"10.1186/s13195-020-00646-x","title":"One third of dementia cases can be prevented within the next 25 years by tackling risk factors. The case “for” and “against”","year":2020,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Parkwood Institute; Lawson Health Research Institute; Ontario Brain Institute; Western University","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; University College London; National Institute for Health and Care Research; Consortium canadien en neurodégénérescence associée au vieillissement","keywords":"Dementia; Medicine; Gerontology; Psychological intervention; Population; Randomized controlled trial; Cognitive decline; Disease; Psychiatry; Environmental health; Surgery; Internal medicine","score_opus":0.16229025176257209,"score_gpt":0.39077560192910676,"score_spread":0.22848535016653468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042078075","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9693062,0.01853665,0.00006640465,0.009042058,0.00003009518,0.0026665376,0.00015711323,0.000026713355,0.00016827561],"genre_scores_gemma":[0.9930425,0.0052255974,0.000105729254,0.001138126,0.0001034038,0.000187278,0.00006161126,0.000041744308,0.00009398086],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996872,0.0008310977,0.00036143095,0.00041013226,0.00094301935,0.0005823084],"domain_scores_gemma":[0.9973102,0.0014085309,0.00012648404,0.00040299332,0.00045357484,0.00029817622],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021233363,0.00019199219,0.0003077246,0.00010177396,0.0005370706,0.00012961903,0.00031856692,0.00007574239,0.00013064353],"category_scores_gemma":[0.0006018193,0.00011412828,0.00013093442,0.0005184194,0.00064794265,0.00011446414,0.00017775902,0.00072726107,0.0000045541024],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008833999,0.0029689632,0.20712784,0.0003571502,0.036150783,0.0013989735,0.05994292,0.000015314768,0.2034906,0.00081433996,0.05977115,0.41912797],"study_design_scores_gemma":[0.029692031,0.02687387,0.11502234,0.0005436129,0.0050310516,0.00050311745,0.08851149,0.0070057837,0.58952343,0.0014101176,0.13427044,0.0016127181],"about_ca_topic_score_codex":0.002282301,"about_ca_topic_score_gemma":0.00017685002,"teacher_disagreement_score":0.41751525,"about_ca_system_score_codex":0.000018810519,"about_ca_system_score_gemma":0.0002501965,"threshold_uncertainty_score":0.46540162},"labels":[],"label_agreement":null},{"id":"W3043260270","doi":"10.1186/s13195-020-00653-y","title":"Cardiovascular risk factors indirectly affect acute post-stroke cognition through stroke severity and prior cognitive impairment: a moderated mediation analysis","year":2020,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Chest Heart and Stroke Scotland; Chest, Heart and Stroke Association Scotland; Stroke Association","keywords":"Affect (linguistics); Stroke (engine); Mediation; Cognition; Neurology; Medicine; Cognitive impairment; Cognitive aging; Clinical psychology; Psychology; Psychiatry","score_opus":0.06256120809597616,"score_gpt":0.36306830423421843,"score_spread":0.3005070961382423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043260270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9827984,0.009201709,0.0012802188,0.0008859403,0.00003654444,0.0038272473,0.0011580774,0.00015284882,0.0006589899],"genre_scores_gemma":[0.9851734,0.012346229,0.00017035865,0.000498121,0.00016716648,0.00036110412,0.0011266676,0.00006519022,0.0000917441],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9927444,0.0019911043,0.00043550442,0.0010814952,0.0026934843,0.0010540478],"domain_scores_gemma":[0.9962112,0.0007624762,0.00013210223,0.00038113238,0.0018149024,0.00069819274],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019223571,0.00044884125,0.00095304375,0.0006925297,0.0006658756,0.0002533608,0.00020461266,0.00024205825,0.0005975429],"category_scores_gemma":[0.0005456905,0.00036845956,0.00079242024,0.0019827448,0.0004388845,0.0005855371,0.00018135931,0.0012261686,0.000079666635],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018149998,0.0017081638,0.5063618,0.00010867588,0.26331145,0.00034141945,0.017680196,0.000015054103,0.028365064,0.0000073504584,0.0003042937,0.16364658],"study_design_scores_gemma":[0.012087801,0.006790118,0.82347816,0.000051985855,0.014485722,0.000017803397,0.0043837545,0.0031714113,0.13417993,0.00006985671,0.00067859894,0.00060484576],"about_ca_topic_score_codex":0.0008316223,"about_ca_topic_score_gemma":0.000033898934,"teacher_disagreement_score":0.3171164,"about_ca_system_score_codex":0.000080660044,"about_ca_system_score_gemma":0.00035980434,"threshold_uncertainty_score":0.99987674},"labels":[],"label_agreement":null},{"id":"W3091323015","doi":"10.1186/s13195-020-00696-1","title":"Cerebrospinal fluid A beta 1–40 peptides increase in Alzheimer’s disease and are highly correlated with phospho-tau in control individuals","year":2020,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Ministère de l'Éducation Nationale; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Eisai; Association France Alzheimer; Servier; EU Joint Programme – Neurodegenerative Disease Research; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Cerebrospinal fluid; Medicine; Context (archaeology); Alzheimer's disease; Internal medicine; Neurology; Pathology; Amyloid beta; Disease; Biology","score_opus":0.07116721444258602,"score_gpt":0.34492016127414893,"score_spread":0.2737529468315629,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091323015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7953355,0.19030744,0.00000388483,0.009924017,0.000021094815,0.003841543,0.00021916775,0.00010007945,0.00024730194],"genre_scores_gemma":[0.99142116,0.005678595,0.00012797838,0.00150253,0.0001380019,0.00077416934,0.00020998568,0.00013292811,0.000014656796],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99334985,0.0009827182,0.00065761345,0.0012722561,0.002054115,0.0016834326],"domain_scores_gemma":[0.9953376,0.0005511112,0.00014001882,0.0007407009,0.00045676093,0.002773788],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010642257,0.0006212521,0.0010160947,0.0007118807,0.0002783076,0.00018542686,0.0004375251,0.00021061738,0.00031651516],"category_scores_gemma":[0.00022349138,0.00047785678,0.00016034121,0.0018157994,0.00084481033,0.0004641465,0.00019552125,0.0013570202,0.00019554597],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.040111676,0.002312495,0.9214622,0.00005562155,0.018029332,0.005355492,0.0010475959,0.00002152955,0.000322973,0.00012540643,0.0023418157,0.008813873],"study_design_scores_gemma":[0.0331887,0.0040400457,0.9557876,0.00054271333,0.0012676695,0.000040633335,0.0006803589,0.0010590762,0.0013052297,0.0002166353,0.0012469084,0.0006244177],"about_ca_topic_score_codex":0.002271057,"about_ca_topic_score_gemma":0.00015701397,"teacher_disagreement_score":0.19608568,"about_ca_system_score_codex":0.00011928769,"about_ca_system_score_gemma":0.0012954121,"threshold_uncertainty_score":0.9997673},"labels":[],"label_agreement":null},{"id":"W3106577603","doi":"10.1186/s13195-020-00747-7","title":"Conditional genetic deletion of CSF1 receptor in microglia ameliorates the physiopathology of Alzheimer’s disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Microglia; TREM2; Pathophysiology; Knockout mouse; Hippocampus; Conditional gene knockout; Medicine; Neuroscience; Immune system; Cognitive decline; Dementia; Receptor; Neuroinflammation; Biology; Pathology; Immunology; Disease; Internal medicine; Inflammation; Gene","score_opus":0.1621458909826665,"score_gpt":0.38044871234439837,"score_spread":0.21830282136173187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3106577603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919973,0.004112715,0.000085962456,0.0028700067,0.00017513907,0.00058484543,0.00007662399,0.00002123523,0.0000761527],"genre_scores_gemma":[0.9959439,0.0027794384,0.0002369947,0.0007444226,0.00007486136,0.0001002721,0.000029163135,0.000026397112,0.00006453372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996044,0.0019399793,0.0004715758,0.00046622075,0.0007488583,0.00032938775],"domain_scores_gemma":[0.99832934,0.00049301895,0.00015473552,0.00050621614,0.00041369617,0.00010296322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005490217,0.0001432404,0.00021592878,0.00023700017,0.00016569768,0.000037400452,0.00035897575,0.000053717944,0.00067147927],"category_scores_gemma":[0.0003336639,0.00011487806,0.000099705685,0.00093530247,0.00047059965,0.00013250513,0.00009542584,0.00030192416,0.000081626604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017104624,0.00022485558,0.0001515616,0.0000049466944,0.000017791499,0.000037520203,0.00020148279,0.00022269023,0.9902599,0.004484883,0.0006650049,0.0035583032],"study_design_scores_gemma":[0.0005783173,0.00014552106,0.0075423364,0.000012424559,0.000012415592,0.00000982927,0.000052054605,0.00051876967,0.9856362,0.0034812898,0.0019144757,0.00009641871],"about_ca_topic_score_codex":0.000012891022,"about_ca_topic_score_gemma":0.0000073369592,"teacher_disagreement_score":0.007390775,"about_ca_system_score_codex":0.000009360482,"about_ca_system_score_gemma":0.00029673934,"threshold_uncertainty_score":0.73522276},"labels":[],"label_agreement":null},{"id":"W3109574781","doi":"10.1186/s13195-020-00726-y","title":"Alpha-amylase 1A copy number variants and the association with memory performance and Alzheimer’s dementia","year":2020,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Vetenskapsrådet; Lunds Universitet; Crafoordska Stiftelsen; Greta och Johan Kocks stiftelser; Demensförbundet","keywords":"Copy-number variation; Dementia; Medicine; Hazard ratio; Neurology; Effects of sleep deprivation on cognitive performance; Internal medicine; Cognition; Biology; Psychiatry; Gene; Confidence interval; Genetics; Disease","score_opus":0.04633760142139679,"score_gpt":0.29650781582284413,"score_spread":0.2501702144014473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3109574781","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9752943,0.018123202,0.000045592187,0.0038054409,0.000038251404,0.00052137836,0.000018368222,0.000011906491,0.002141559],"genre_scores_gemma":[0.99222136,0.0061774966,0.00024646852,0.0008912708,0.00020271195,0.00007895681,0.00003194859,0.00002233257,0.00012745461],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985841,0.00030053838,0.00015993098,0.00031308382,0.00031393225,0.00032840174],"domain_scores_gemma":[0.99934906,0.00007067727,0.000069703776,0.00021203062,0.0001800254,0.00011852363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081131683,0.00014076513,0.00014537676,0.000019593106,0.00036592848,0.00011689816,0.00017804632,0.00009226719,0.00011289414],"category_scores_gemma":[0.000028631137,0.00009345316,0.00003141022,0.000119151766,0.00023328363,0.000018997658,0.00012706856,0.00019154293,0.000023318662],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021036513,0.00065578526,0.5707415,0.000103686754,0.056018963,0.00004297805,0.022613164,0.00017668713,0.12519525,0.006025228,0.068266004,0.12912425],"study_design_scores_gemma":[0.031762753,0.0052504563,0.12064814,0.00005593023,0.0018401446,0.0001652143,0.0045388667,0.002156755,0.46480522,0.00065266027,0.366371,0.0017528677],"about_ca_topic_score_codex":0.00011957994,"about_ca_topic_score_gemma":0.000016866608,"teacher_disagreement_score":0.45009333,"about_ca_system_score_codex":0.000005936349,"about_ca_system_score_gemma":0.00009863293,"threshold_uncertainty_score":0.38109094},"labels":[],"label_agreement":null},{"id":"W3111571127","doi":"10.1186/s13195-021-00869-6","title":"White matter hyperintensities in autopsy-confirmed frontotemporal lobar degeneration and Alzheimer’s disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; Health Sciences Centre; Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Université de Montréal; Weston Brain Institute","keywords":"Frontotemporal lobar degeneration; Progressive supranuclear palsy; Medicine; Dementia; Hyperintensity; Frontotemporal dementia; Depression (economics); Corticobasal degeneration; Autopsy; Alzheimer's disease; White matter; Pathology; Psychology; Disease; Magnetic resonance imaging; Radiology","score_opus":0.10276865668360036,"score_gpt":0.38483358520744915,"score_spread":0.2820649285238488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111571127","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93895614,0.0404383,0.00003457634,0.014597132,0.00009895148,0.001093041,0.000015569298,0.000039923696,0.004726347],"genre_scores_gemma":[0.99191403,0.0024126791,0.00034625796,0.001986127,0.00019181333,0.00024450393,0.00013958263,0.0000484675,0.0027165462],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9964889,0.0006442138,0.00033851704,0.00065003353,0.0010601305,0.00081819243],"domain_scores_gemma":[0.99806434,0.000114827984,0.000032568405,0.00047660575,0.00081125734,0.0005003729],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010268182,0.00023553775,0.00035115145,0.0003601587,0.00019836832,0.00020261486,0.00013076048,0.00009777769,0.0033978773],"category_scores_gemma":[0.00006782648,0.00020597891,0.00010080196,0.00046704678,0.00037054665,0.0002715215,0.00015087494,0.0005341113,0.0002609219],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015361822,0.0004991599,0.9563722,0.000024371564,0.0005888257,0.0007797638,0.0007832306,0.0000012242822,0.0056204605,0.00014389624,0.006794698,0.026856001],"study_design_scores_gemma":[0.003071265,0.0003455412,0.96932125,0.00008107709,0.00009628982,0.000052990104,0.0009990605,0.00034471965,0.012458894,0.00036667517,0.012639691,0.00022257294],"about_ca_topic_score_codex":0.00027003392,"about_ca_topic_score_gemma":0.00012576481,"teacher_disagreement_score":0.052957866,"about_ca_system_score_codex":0.00004975079,"about_ca_system_score_gemma":0.00060005864,"threshold_uncertainty_score":0.9975132},"labels":[],"label_agreement":null},{"id":"W3113024939","doi":"10.1186/s13195-021-00873-w","title":"Plasma amyloid-β oligomerization assay as a pre-screening test for amyloid status","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Janssen Pharmaceuticals; Avid Radiopharmaceuticals; Alzheimer Nederland; GIESKES-STRIJBIS FONDS; Stichting Dioraphte; European Commission; Sanofi; Roche Nederland; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Danone; Weston Brain Institute; Biogen; ZonMw; Janssen Prevention Center; Center for Translational Molecular Medicine; Pfizer; Eli Lilly and Company","keywords":"Internal medicine; Medicine; Amyloid (mycology); Amyloidosis; Biomarker; Oncology; Cohort; Positron emission tomography; Dementia; Population; Logistic regression; Gastroenterology; Pathology; Nuclear medicine; Biology; Disease","score_opus":0.06975630716968556,"score_gpt":0.38215355834122594,"score_spread":0.3123972511715404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3113024939","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94306505,0.04107316,0.0053568417,0.0038258564,0.00034705835,0.0031834536,0.00041706386,0.00013471441,0.0025968123],"genre_scores_gemma":[0.9714705,0.016769366,0.0051669683,0.00089131866,0.0004677875,0.0014418982,0.0013351645,0.0001567166,0.0023002776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99641424,0.00046163241,0.00037959428,0.00094297127,0.000656409,0.0011451655],"domain_scores_gemma":[0.9972646,0.0006813657,0.00011794214,0.00088155473,0.0007203761,0.000334127],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00077450555,0.0003597549,0.00033984127,0.00016657196,0.0004363415,0.00019000786,0.0004127046,0.00029065166,0.00024582792],"category_scores_gemma":[0.0010883003,0.0003400837,0.00025852802,0.0005132057,0.00021194488,0.00002491521,0.00022826335,0.00027121842,0.00005606419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00085506955,0.0008932765,0.0398712,0.000018621504,0.002475861,0.000031372947,0.000403135,0.00015460885,0.8086708,0.00019542042,0.008201013,0.13822962],"study_design_scores_gemma":[0.0026027549,0.0012429969,0.011490828,0.000022666478,0.000070034104,0.000015422904,0.00029491077,0.00019992521,0.7506756,0.00012930167,0.23289402,0.00036153223],"about_ca_topic_score_codex":0.00019774678,"about_ca_topic_score_gemma":0.00012364108,"teacher_disagreement_score":0.224693,"about_ca_system_score_codex":0.00004819583,"about_ca_system_score_gemma":0.00051993656,"threshold_uncertainty_score":0.9999051},"labels":[],"label_agreement":null},{"id":"W3114255343","doi":"10.1186/s13195-021-00924-2","title":"Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer’s disease","year":2021,"lang":"en","type":"preprint","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; Deutsches Zentrum für Neurodegenerative Erkrankungen; Freie Universität Berlin; H. Lundbeck A/S; Universität Rostock; Servier; Eisai; Deutsche Forschungsgemeinschaft; Northern California Institute for Research and Education; F. Hoffmann-La Roche; University of Southern California; Pfizer; BioClinica; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Convolutional neural network; Relevance (law); Dementia; Atrophy; Discriminative model; Magnetic resonance imaging; Clinical significance; Computer science; Artificial intelligence; Pattern recognition (psychology); Psychology; Disease; Medicine; Pathology; Radiology","score_opus":0.1401646399574572,"score_gpt":0.4485761138401771,"score_spread":0.3084114738827199,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3114255343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8820003,0.105144985,0.002059173,0.00087957387,0.00063634606,0.008592237,0.0000714171,0.00006599489,0.0005499642],"genre_scores_gemma":[0.99293804,0.0024871198,0.0006528753,0.0002080828,0.0004101347,0.0010549786,0.002143232,0.000075454605,0.000030064355],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9890883,0.003906502,0.0010165974,0.0013592044,0.0036173386,0.0010120658],"domain_scores_gemma":[0.99183685,0.001047634,0.00036121893,0.0010432764,0.0053030387,0.00040801457],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0056452565,0.00044973852,0.0008167011,0.00062515447,0.00019326915,0.00013743884,0.0004173681,0.00028967555,0.0010947248],"category_scores_gemma":[0.0008756969,0.00043732516,0.0003179508,0.0010653798,0.0006071156,0.0003578856,0.00090169185,0.0019383427,0.000018288512],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0160231,0.0046669375,0.2916498,0.0005254403,0.0055502024,0.00019294453,0.0017924724,0.00466495,0.0104909595,0.00012617091,0.0010495498,0.6632675],"study_design_scores_gemma":[0.005705505,0.0010321513,0.68611306,0.0012426716,0.0008488888,0.000010655389,0.0004661071,0.296473,0.004540916,0.0025722187,0.00045051996,0.00054429163],"about_ca_topic_score_codex":0.0012396957,"about_ca_topic_score_gemma":0.000158483,"teacher_disagreement_score":0.6627232,"about_ca_system_score_codex":0.00039124637,"about_ca_system_score_gemma":0.0027656283,"threshold_uncertainty_score":0.9998184},"labels":[],"label_agreement":null},{"id":"W3118259936","doi":"10.1186/s13195-020-00713-3","title":"Four subgroups based on tau levels in Alzheimer’s disease observed in two independent cohorts","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Pfizer; Biogen; BioClinica; Alzheimer Nederland; Eisai; ZonMw; Northern California Institute for Research and Education; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Dementia; Cohort; Disease; Biomarker; Tau pathology; Internal medicine; Cognitive decline; Alzheimer's disease; Psychology; Medicine; Cohort study; Cognitive impairment; Oncology; Biology","score_opus":0.22540027928629314,"score_gpt":0.43077530383217866,"score_spread":0.20537502454588552,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118259936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9711552,0.012767246,0.000033641958,0.008673705,0.00013357961,0.0029159796,0.00003345438,0.000057199926,0.004229939],"genre_scores_gemma":[0.99530786,0.0010952192,0.00013070178,0.0018837155,0.00015856954,0.0007634728,0.00014894192,0.00008687911,0.00042465105],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99165636,0.0019308073,0.00060158304,0.0011030426,0.0031063445,0.0016018527],"domain_scores_gemma":[0.9965244,0.0007539871,0.00005933633,0.0010327861,0.0007883676,0.0008411378],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0038102823,0.00038032798,0.00059999456,0.0010684195,0.00017114673,0.00016323994,0.00041600346,0.00012481063,0.0033357334],"category_scores_gemma":[0.00039682153,0.00034117603,0.0002293723,0.0019830307,0.00026076005,0.0002326846,0.00020355078,0.0015487826,0.00026917105],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004153444,0.003696321,0.9048368,0.000026621134,0.00068862713,0.0075299037,0.00023265652,0.0000559253,0.0057669897,0.0002236161,0.000870485,0.071918644],"study_design_scores_gemma":[0.012236428,0.0008052599,0.96045744,0.0003018383,0.00008443637,0.000013215959,0.00025352192,0.0017143498,0.02060214,0.0006636389,0.0025409078,0.0003268233],"about_ca_topic_score_codex":0.0009298601,"about_ca_topic_score_gemma":0.0010545327,"teacher_disagreement_score":0.071591824,"about_ca_system_score_codex":0.00021020105,"about_ca_system_score_gemma":0.0021115239,"threshold_uncertainty_score":0.99990404},"labels":[],"label_agreement":null},{"id":"W3118711961","doi":"10.1186/s13195-020-00745-9","title":"Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McMaster University","funders":"Institute of Neurosciences, Mental Health and Addiction; Canadian Institutes of Health Research; Consortium canadien en neurodégénérescence associée au vieillissement","keywords":"Autoimmunity; Immunology; Immunosuppression; Medicine; Neurodegeneration; Immunosenescence; Autoantibody; Epigenetics; Disease; Biology; Internal medicine; Immune system; Gene; Genetics; Antibody","score_opus":0.06647213425398009,"score_gpt":0.387684609700037,"score_spread":0.3212124754460569,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118711961","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.74204975,0.25547877,0.0000015449473,0.0005244252,0.000105103136,0.0016283916,0.000052139567,0.00003324742,0.0001266307],"genre_scores_gemma":[0.96386135,0.035202093,0.00003239071,0.00005298069,0.00006553628,0.00034136756,0.0002876695,0.00009027424,0.0000663283],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.994543,0.0012462524,0.00047980645,0.0008671013,0.0016803214,0.0011835024],"domain_scores_gemma":[0.9969188,0.0007601627,0.000104742576,0.0008602575,0.00048072523,0.0008753415],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036836314,0.00041300006,0.0006885023,0.00050351804,0.00024780742,0.00007370877,0.000271269,0.00021405016,0.0005865965],"category_scores_gemma":[0.00016264994,0.00034625802,0.00025239383,0.0008039059,0.00052258495,0.00014501301,0.00024290862,0.0007864265,0.000054003503],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03503297,0.055760648,0.11907884,0.00055274647,0.07283606,0.009863771,0.001453435,0.000013138706,0.24562424,0.00011230604,0.0050985124,0.45457333],"study_design_scores_gemma":[0.018848673,0.007282132,0.6736798,0.001533764,0.0019083883,0.000014168126,0.00016846639,0.00037965432,0.29473814,0.0003039109,0.0005998262,0.0005430334],"about_ca_topic_score_codex":0.00033978085,"about_ca_topic_score_gemma":0.000057317484,"teacher_disagreement_score":0.554601,"about_ca_system_score_codex":0.00017993094,"about_ca_system_score_gemma":0.0010766039,"threshold_uncertainty_score":0.99989897},"labels":[],"label_agreement":null},{"id":"W3119266093","doi":"10.1186/s13195-020-00754-8","title":"Association between polygenic risk score of Alzheimer’s disease and plasma phosphorylated tau in individuals from the Alzheimer’s Disease Neuroimaging Initiative","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Medical Research Council; National Institutes of Health; Hjartavernd; Centre hospitalier régional universitaire de Lille; Alzheimerfonden; Hjärnfonden; Alzheimer's Drug Discovery Foundation; Erasmus Medisch Centrum; Bundesministerium für Bildung und Forschung; Institut National de la Santé et de la Recherche Médicale; Université de Lille; Wellcome Trust; National Heart, Lung, and Blood Institute; Vetenskapsrådet; Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease; National Institute on Aging; Alzheimer's Association","keywords":"Medicine; Dementia; Apolipoprotein E; Disease; Biomarker; Alzheimer's disease; Neuroimaging; Neurology; Internal medicine; Oncology; Alzheimer's Disease Neuroimaging Initiative; Pathology; Psychiatry; Biology","score_opus":0.11041448163348028,"score_gpt":0.3775321854538675,"score_spread":0.26711770382038724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3119266093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8907401,0.097992696,0.000005817795,0.008129871,0.00007034688,0.0020091666,0.0006998284,0.0000417288,0.00031047006],"genre_scores_gemma":[0.98316187,0.014902418,0.00006407236,0.00064134225,0.00022980334,0.00025364073,0.0006012246,0.000079014964,0.00006662802],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99190235,0.0028762526,0.00072157814,0.00092958636,0.0024509637,0.0011192919],"domain_scores_gemma":[0.9941711,0.0028534934,0.00029349924,0.00077717577,0.0010887105,0.00081604015],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0029505438,0.00038684873,0.00064337783,0.00041320012,0.00042805643,0.00019626986,0.00040026492,0.0001422401,0.00075650384],"category_scores_gemma":[0.0014101196,0.00030565233,0.00024086573,0.0015424881,0.00052628934,0.00038046966,0.00043546714,0.0014981108,0.000059485323],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00087678,0.0005260301,0.9348233,0.000009223336,0.0070811356,0.00016487313,0.0012666553,0.0000016869411,0.00068549166,0.000026859514,0.0016464759,0.052891526],"study_design_scores_gemma":[0.0047119744,0.0003210148,0.9737742,0.0002109615,0.0025497342,0.0000016858714,0.0007193628,0.00019348474,0.014305705,0.001621795,0.0013208,0.00026928398],"about_ca_topic_score_codex":0.0012073427,"about_ca_topic_score_gemma":0.00006170935,"teacher_disagreement_score":0.09242178,"about_ca_system_score_codex":0.00008798677,"about_ca_system_score_gemma":0.0013696662,"threshold_uncertainty_score":0.99993956},"labels":[],"label_agreement":null},{"id":"W3120774838","doi":"10.1186/s13195-020-00736-w","title":"Portals to frailty? Data-driven analyses detect early frailty profiles","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Frailty in Older Adults","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"National Institute on Aging; Social Sciences and Humanities Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates; Canada Research Chairs; National Institutes of Health; Consortium canadien en neurodégénérescence associée au vieillissement","keywords":"Geriatric psychiatry; Neurology; Medicine; Gerontology; Frailty Index; Psychiatry","score_opus":0.4680333247054968,"score_gpt":0.5102909910895511,"score_spread":0.042257666384054315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120774838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91892064,0.045863904,0.0004722759,0.021557024,0.00040907366,0.0035778554,0.00048250402,0.0004203636,0.008296386],"genre_scores_gemma":[0.97777194,0.0021969527,0.010889921,0.0022200355,0.0008896684,0.00031241344,0.0007531824,0.00017518342,0.0047907033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99363905,0.00069238327,0.00061699725,0.0014188169,0.0023274964,0.0013052435],"domain_scores_gemma":[0.9931914,0.00067320757,0.0000862024,0.0037518379,0.0014311644,0.00086613995],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0012991431,0.0004033527,0.000743433,0.00053130457,0.00032617702,0.00023943084,0.0012683029,0.0002469076,0.0035029077],"category_scores_gemma":[0.0011941118,0.00033907458,0.00020934826,0.002086155,0.0003291944,0.00044763274,0.0007829589,0.0011092437,0.0015283149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010492492,0.0008118253,0.008744496,0.00005135578,0.0065192105,0.0019793718,0.0021348097,0.000024863877,0.45887402,0.0000912716,0.16702072,0.3526988],"study_design_scores_gemma":[0.0031628152,0.0017858795,0.07532718,0.00026762573,0.00026284298,0.0001504065,0.00059157185,0.00030861032,0.55097884,0.00036869137,0.3661381,0.00065743126],"about_ca_topic_score_codex":0.0011286095,"about_ca_topic_score_gemma":0.0004129537,"teacher_disagreement_score":0.35204136,"about_ca_system_score_codex":0.00007286265,"about_ca_system_score_gemma":0.001034194,"threshold_uncertainty_score":0.9999061},"labels":[],"label_agreement":null},{"id":"W3126285145","doi":"10.1186/s13195-020-00756-6","title":"Cerebrospinal fluid N-224 tau helps discriminate Alzheimer’s disease from subjective cognitive decline and other dementias","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Marcus och Amalia Wallenbergs minnesfond; EU Joint Programme – Neurodegenerative Disease Research; Alzheimer Nederland; Göteborgs Universitet; Knut och Alice Wallenbergs Stiftelse; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Region Skåne; Weston Brain Institute; Alzheimerfonden; Hjärnfonden; ParkinsonFörbundet; Alzheimer's Association","keywords":"Progressive supranuclear palsy; Cohort; Cerebrospinal fluid; Dementia; Medicine; Internal medicine; Tau protein; Cognitive decline; Atrophy; Gastroenterology; Cohort study; Alzheimer's disease; Disease; Oncology; Pathology","score_opus":0.12145428485701874,"score_gpt":0.4156382325152447,"score_spread":0.2941839476582259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126285145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8952626,0.09272732,0.00024040812,0.0048208046,0.00014035514,0.0021005964,0.000322099,0.00008874548,0.0042970595],"genre_scores_gemma":[0.9883348,0.0062051644,0.0003505416,0.0027401128,0.00049351674,0.00049634953,0.00042326452,0.00012625981,0.0008300392],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99335515,0.0012027893,0.00049385993,0.0013229721,0.0022184986,0.0014067205],"domain_scores_gemma":[0.99551946,0.00075316295,0.000084932326,0.00065871805,0.0017988208,0.0011849008],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013817833,0.00047937644,0.00058847235,0.0003821461,0.0005998563,0.00033386835,0.00030661066,0.00015461899,0.00550379],"category_scores_gemma":[0.00036108782,0.0004067208,0.00026057253,0.00083944504,0.00097570417,0.0003354238,0.000617465,0.00092439924,0.00041873715],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012752208,0.003288721,0.7361353,0.00004828347,0.010416603,0.00162544,0.001850777,2.6731416e-7,0.024708295,0.0005704609,0.0022546533,0.20634902],"study_design_scores_gemma":[0.008724198,0.0016471469,0.8618999,0.00028938014,0.0012628515,0.000039258197,0.0026664163,0.00012140973,0.10510846,0.0031374951,0.014616797,0.00048668924],"about_ca_topic_score_codex":0.0010029401,"about_ca_topic_score_gemma":0.00014972202,"teacher_disagreement_score":0.20586233,"about_ca_system_score_codex":0.000058850568,"about_ca_system_score_gemma":0.0009245328,"threshold_uncertainty_score":0.9998385},"labels":[],"label_agreement":null},{"id":"W3128082452","doi":"10.1186/s13195-021-00777-9","title":"Early anterior cingulate involvement is seen in presymptomatic MAPT P301L mutation carriers","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Medical Imaging Techniques and Applications","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Medical Research Council; Canadian Institutes of Health Research; Alzheimer Society; National Institute for Health and Care Research; Alzheimer's Society; Brain Research UK; Université Laval","keywords":"Mutation; Asymptomatic; Atrophy; Anterior cingulate cortex; Internal medicine; Asymptomatic carrier; Medicine; Pathology; Psychology; Biology; Oncology; Genetics; Neuroscience; Cognition","score_opus":0.1144855477863432,"score_gpt":0.4266629853914084,"score_spread":0.3121774376050652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128082452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9687136,0.0060440204,0.00035468664,0.022532776,0.00003922809,0.0012997582,0.0000083796185,0.0001120188,0.0008955203],"genre_scores_gemma":[0.9903261,0.0016698767,0.004881796,0.0018933984,0.00008852461,0.00041106393,0.000038362246,0.00003800368,0.0006528826],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978072,0.00020531428,0.00034690392,0.00039198808,0.0007847018,0.00046388045],"domain_scores_gemma":[0.9986738,0.000115309325,0.00004461977,0.00059601106,0.00031986187,0.00025039326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008727906,0.0001331693,0.00025662273,0.00022446887,0.000111689114,0.00006739571,0.00018066095,0.0000884034,0.00073440897],"category_scores_gemma":[0.000080067686,0.000115564704,0.000079463374,0.0007035528,0.00017442094,0.000092290844,0.00008503149,0.00046070336,0.00006380607],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053401507,0.0017318936,0.037363585,0.00023648243,0.0020994563,0.001206448,0.022411618,0.0000036057847,0.4255112,0.0011981621,0.05046527,0.45723826],"study_design_scores_gemma":[0.00914108,0.0016389507,0.17560425,0.0016822162,0.0002261639,0.00015406989,0.0020795187,0.009467804,0.6407796,0.01077905,0.14762618,0.00082108553],"about_ca_topic_score_codex":0.0007342359,"about_ca_topic_score_gemma":0.000020456891,"teacher_disagreement_score":0.45641717,"about_ca_system_score_codex":0.000067353445,"about_ca_system_score_gemma":0.00028580442,"threshold_uncertainty_score":0.80412626},"labels":[],"label_agreement":null},{"id":"W3129177568","doi":"10.1186/s13195-021-00778-8","title":"The use of angiotensin-converting enzyme inhibitors vs. angiotensin receptor blockers and cognitive decline in Alzheimer’s disease: the importance of blood-brain barrier penetration and APOE ε4 carrier status","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; University of Ottawa; Sunnybrook Hospital; Health Sciences Centre; Canada Research Chairs; Heart and Stroke Foundation; Sunnybrook Health Science Centre; Toronto Rehabilitation Institute; University of Toronto","funders":"National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; Fondation Brain Canada; Heart and Stroke Foundation of Canada; Weston Brain Institute; Alzheimer's Drug Discovery Foundation; Alzheimer's Association; Michael J. Fox Foundation for Parkinson's Research","keywords":"Medicine; Episodic memory; Trail Making Test; Internal medicine; Verbal fluency test; Alzheimer's disease; Dementia; Digit symbol substitution test; Oncology; Psychology; Cognition; Audiology; Psychiatry; Neuropsychology; Disease; Pathology","score_opus":0.07024562183453538,"score_gpt":0.3575929111912644,"score_spread":0.28734728935672904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129177568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8882204,0.0925718,0.000004203314,0.017564168,0.000050666335,0.0014699701,0.000082004866,0.000011192917,0.000025576033],"genre_scores_gemma":[0.9876766,0.010482813,0.00020599517,0.0011762984,0.00010806473,0.00008243504,0.000082652004,0.000046346715,0.00013878518],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99547625,0.0011514383,0.00065462437,0.0005758653,0.0013116435,0.0008301635],"domain_scores_gemma":[0.9947005,0.002529265,0.00017415857,0.0004677959,0.0017142005,0.00041407827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023985673,0.00025940052,0.0004247838,0.0002449074,0.00034833053,0.00012622689,0.0001367368,0.0001165907,0.00013535807],"category_scores_gemma":[0.0018245333,0.00016996232,0.00013666823,0.00093923573,0.0014600058,0.00024811906,0.0002478074,0.00060738093,0.0000018591031],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044094226,0.00038987416,0.84670466,0.000025219319,0.0028659191,0.00013754636,0.001725857,0.0000010523235,0.07185514,0.000087093904,0.0039307782,0.06786746],"study_design_scores_gemma":[0.005654231,0.0011066952,0.6909068,0.00033750077,0.00070224906,0.000028120085,0.002240815,0.00050509564,0.27835006,0.000202366,0.019694991,0.00027107607],"about_ca_topic_score_codex":0.00059660885,"about_ca_topic_score_gemma":0.0004886257,"teacher_disagreement_score":0.20649493,"about_ca_system_score_codex":0.000020337515,"about_ca_system_score_gemma":0.0008571505,"threshold_uncertainty_score":0.6930862},"labels":[],"label_agreement":null},{"id":"W3129955977","doi":"10.1186/s13195-021-00785-9","title":"Data-driven FDG-PET subtypes of Alzheimer’s disease-related neurodegeneration","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; European Regional Development Fund; Instituto de Salud Carlos III; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Vetenskapsrådet; Eisai; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Neurodegeneration; Dementia; Atrophy; Neuroimaging; Biomarker; Disease; Cognitive decline; Neuroscience; Alzheimer's disease; Psychology; Pathology; Medicine; Oncology; Biology","score_opus":0.17681921055466548,"score_gpt":0.423668389262825,"score_spread":0.24684917870815953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129955977","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.922844,0.06060502,0.00006277184,0.008421816,0.00022880861,0.0018257464,0.00024426356,0.00009864921,0.0056689414],"genre_scores_gemma":[0.98817515,0.007897365,0.000403589,0.00034700817,0.00018792282,0.00009230353,0.0017284544,0.00006434726,0.0011038835],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9950286,0.0009947661,0.00050062186,0.0008280375,0.0019001305,0.0007478284],"domain_scores_gemma":[0.99599946,0.00024475832,0.000083092964,0.0015521824,0.0016278351,0.0004926915],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014805772,0.00022580217,0.00040034417,0.00035068556,0.00023669134,0.000093202674,0.00049449736,0.00007372475,0.0030768851],"category_scores_gemma":[0.0002970947,0.00019367608,0.00015264294,0.0011079679,0.000409102,0.0003474007,0.00042623488,0.0006201342,0.00027166365],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0049728644,0.006597006,0.16905843,0.00014513617,0.013950027,0.003593332,0.0007998678,0.000054089076,0.4269569,0.0027445166,0.08060658,0.29052126],"study_design_scores_gemma":[0.009049678,0.0024170852,0.51016456,0.0002569092,0.0014691756,0.00018348594,0.0005528171,0.008529343,0.37028706,0.0013835244,0.09502511,0.000681283],"about_ca_topic_score_codex":0.00009254669,"about_ca_topic_score_gemma":0.000025042595,"teacher_disagreement_score":0.34110612,"about_ca_system_score_codex":0.000022380604,"about_ca_system_score_gemma":0.0011654524,"threshold_uncertainty_score":0.99783444},"labels":[],"label_agreement":null},{"id":"W3130913951","doi":"10.1186/s13195-021-00784-w","title":"Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer’s subjects?","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; National Institute for Health and Care Research; Novo Nordisk; Imperial College London; Imperial College Healthcare NHS Trust; Alzheimer's Society; Queen's University Belfast; North Bristol NHS Trust; Queen's University; Pfizer; Menzies Centre for Australian Studies, King's College London, University of London; Eli Lilly and Company","keywords":"Insulin resistance; Internal medicine; Medicine; Endocrinology; Diabetes mellitus; Type 2 diabetes; Neurodegeneration; Insulin; Hyperintensity; Glucose uptake; Grey matter; Carbohydrate metabolism; Population; White matter; Disease; Magnetic resonance imaging; Radiology","score_opus":0.06443717446913935,"score_gpt":0.3810300964820599,"score_spread":0.31659292201292055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130913951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9620653,0.02586132,0.000020923471,0.0063916584,0.00013437506,0.0014606509,0.000008923913,0.000048698206,0.004008145],"genre_scores_gemma":[0.9862983,0.009727858,0.00036993733,0.001142459,0.00020518967,0.0004346631,0.00006667093,0.00005978673,0.0016950932],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9947539,0.0009976517,0.00048655405,0.0008751243,0.0017487584,0.0011380375],"domain_scores_gemma":[0.99694955,0.00039421584,0.000056561767,0.00080786546,0.0014426551,0.00034915976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019531455,0.00026915764,0.00040397848,0.00054329226,0.00026826074,0.00019744672,0.00032343794,0.0001490215,0.00078858895],"category_scores_gemma":[0.00039985593,0.00019208634,0.0001229477,0.001973596,0.00035325388,0.00036387003,0.00016729678,0.0010300957,0.00028744523],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033473612,0.0027053384,0.28870374,0.00011144112,0.001701193,0.0019309957,0.001970201,0.000034422384,0.54781336,0.00046482476,0.0044559226,0.14676124],"study_design_scores_gemma":[0.0037246828,0.0005582612,0.53006554,0.00016466761,0.000066217486,0.000011660551,0.00030572797,0.00016914013,0.44600728,0.00073758827,0.017927451,0.0002617971],"about_ca_topic_score_codex":0.00019374835,"about_ca_topic_score_gemma":0.00042669653,"teacher_disagreement_score":0.2413618,"about_ca_system_score_codex":0.00007221117,"about_ca_system_score_gemma":0.0008683581,"threshold_uncertainty_score":0.8634496},"labels":[],"label_agreement":null},{"id":"W3133501805","doi":"10.1186/s13195-021-00879-4","title":"Data analysis with Shapley values for automatic subject selection in Alzheimer’s disease data sets using interpretable machine learning","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; BioClinica; F. Hoffmann-La Roche; University of Southern California; Biogen; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; National Institute on Aging; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Overfitting; Artificial intelligence; Machine learning; Feature selection; Random forest; Computer science; Test set; Cross-validation; Neuroimaging; Data mining; Medicine; Artificial neural network","score_opus":0.2688370233607937,"score_gpt":0.4751454934411039,"score_spread":0.20630847008031022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133501805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9217718,0.061876394,0.008927552,0.0020983422,0.000058971196,0.003937599,0.0007397105,0.000176116,0.000413501],"genre_scores_gemma":[0.98608804,0.0017704108,0.005339346,0.00017426297,0.000101497295,0.00016765136,0.0060564918,0.00008138668,0.00022093237],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9943922,0.0012785989,0.0004399338,0.0013385873,0.0015067474,0.0010438869],"domain_scores_gemma":[0.9963927,0.0007018238,0.00009016409,0.001586142,0.00082210574,0.00040704277],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00442942,0.0002868411,0.0005873294,0.0010101165,0.00042096397,0.00029706693,0.00087972905,0.000078884594,0.0011554894],"category_scores_gemma":[0.0006594773,0.00023143375,0.00011601446,0.0034310701,0.00020224771,0.0008146224,0.00082769676,0.00080439134,0.000018393846],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005071934,0.0018821504,0.7992978,0.00012439645,0.026671799,0.00037664422,0.0005645723,0.00030703377,0.006721294,0.000019381676,0.0012075228,0.15775548],"study_design_scores_gemma":[0.0035873412,0.00088350376,0.11039793,0.00021537706,0.0039229016,0.000032075193,0.0004653837,0.87345296,0.002698516,0.000118468895,0.0039175176,0.00030799297],"about_ca_topic_score_codex":0.0011656659,"about_ca_topic_score_gemma":0.0010602219,"teacher_disagreement_score":0.87314594,"about_ca_system_score_codex":0.00008488807,"about_ca_system_score_gemma":0.0013889717,"threshold_uncertainty_score":0.9997576},"labels":[],"label_agreement":null},{"id":"W3133942229","doi":"10.1186/s13195-021-00865-w","title":"The Revised Self-Monitoring Scale detects early impairment of social cognition in genetic frontotemporal dementia within the GENFI cohort","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Western University; Montreal Neurological Institute and Hospital; University of Toronto; Occupational Cancer Research Centre; Health Sciences Centre; McGill University Health Centre; Sunnybrook Health Science Centre; Université Laval","funders":"Medical Research Council; Canadian Institutes of Health Research; Universität Ulm; Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta; Universidade de Lisboa; Università degli Studi di Firenze; KU Leuven; Alzheimer's Society; Ministero della Salute; Universidade de Coimbra; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico; Eberhard Karls Universität Tübingen; Karolinska Institutet; Institut National de la Santé et de la Recherche Médicale; Universität Duisburg-Essen; Wellcome Trust; Agence Nationale de la Recherche; National Institute for Health and Care Research; McGill University; Centre National de la Recherche Scientifique; Wolfson Foundation; Brain Research Trust; McGill University Health Centre; University of Oxford; Deutsches Zentrum für Neurodegenerative Erkrankungen; Brain Research UK; Sorbonne Université; Università degli Studi di Milano","keywords":"Frontotemporal dementia; Socioemotional selectivity theory; Psychology; Dementia; Orbitofrontal cortex; Audiology; Cognition; Internal medicine; Neuroscience; Medicine; Disease; Prefrontal cortex","score_opus":0.07737504447675596,"score_gpt":0.37455577694560566,"score_spread":0.2971807324688497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133942229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.975751,0.019067546,0.000008982252,0.0027259698,0.000117615076,0.00194101,0.0000039489755,0.00003122628,0.00035273135],"genre_scores_gemma":[0.9944522,0.0040577943,0.0004940516,0.00006567435,0.00037713762,0.00038871463,0.000008543935,0.00004816708,0.000107759486],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9945703,0.0015824627,0.0005754059,0.00043810313,0.0020197977,0.00081389287],"domain_scores_gemma":[0.9979605,0.00035453207,0.00011599821,0.0005933024,0.0008018662,0.0001737661],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0033757826,0.00019534961,0.00034743082,0.00012384747,0.0006384496,0.00014494095,0.00042395797,0.0001385473,0.00016633114],"category_scores_gemma":[0.000090796835,0.00011718267,0.00015988977,0.0007856059,0.0004365987,0.000106176165,0.0002067032,0.0009127192,0.000040918025],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023424586,0.0008964553,0.7599653,0.000060333336,0.0043685753,0.00016926415,0.0074918224,0.000007709199,0.1704166,0.000052516876,0.00085445674,0.05337451],"study_design_scores_gemma":[0.002317115,0.0005958319,0.9578506,0.00009981808,0.0001228614,0.00001056212,0.0005595455,0.00014792691,0.037051048,0.00022603269,0.0008989905,0.000119672906],"about_ca_topic_score_codex":0.0007236779,"about_ca_topic_score_gemma":0.00015155981,"teacher_disagreement_score":0.19788529,"about_ca_system_score_codex":0.00015324743,"about_ca_system_score_gemma":0.0006223123,"threshold_uncertainty_score":0.49105027},"labels":[],"label_agreement":null},{"id":"W3134948809","doi":"10.1186/s13195-021-00793-9","title":"Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; International Collaboration On Repair Discoveries; University of British Columbia","funders":"Weston Brain Institute","keywords":"Glial fibrillary acidic protein; Immunoassay; Traumatic brain injury; Biomarker; Detection limit; Medicine; Pathology; Chemistry; Immunology; Biochemistry; Chromatography; Antibody","score_opus":0.07194597086601924,"score_gpt":0.3572457405674613,"score_spread":0.28529976970144205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134948809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932391,0.0027811932,0.0017639109,0.00095783535,0.000039636496,0.00094568107,0.00007092964,0.000011207757,0.00019048917],"genre_scores_gemma":[0.9791532,0.00008010899,0.019707171,0.00021363705,0.00017607884,0.0003146541,0.00009845653,0.0000445878,0.0002121177],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99780756,0.00027252638,0.00037369004,0.0004873933,0.00058241526,0.00047640112],"domain_scores_gemma":[0.99892056,0.00004918217,0.000050659277,0.00040450718,0.00042868956,0.00014637604],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008043287,0.00021268925,0.00023788426,0.0001335345,0.00015809956,0.000040079904,0.00020043796,0.00016045399,0.00014963963],"category_scores_gemma":[0.000087702785,0.0001962656,0.00013322012,0.00036427318,0.00017408819,0.00001060687,0.00013732353,0.00020628104,0.000020447718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014201612,0.00014581218,0.000016653214,0.000014954698,0.0005510032,0.000015447135,0.0007447723,0.0000069961734,0.90674704,0.000022116841,0.00015945574,0.090155564],"study_design_scores_gemma":[0.0011322151,0.0005592617,0.0013555769,0.000071722665,0.000007850188,0.000016287933,0.00018693053,0.000027595368,0.9607396,0.00003081281,0.035640966,0.00023114627],"about_ca_topic_score_codex":0.00003178585,"about_ca_topic_score_gemma":0.00012458843,"teacher_disagreement_score":0.08992442,"about_ca_system_score_codex":0.00001554639,"about_ca_system_score_gemma":0.0006812339,"threshold_uncertainty_score":0.80034786},"labels":[],"label_agreement":null},{"id":"W3139606263","doi":"10.1186/s13195-021-00802-x","title":"Plasma pTau181 predicts cortical brain atrophy in aging and Alzheimer’s disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centres Intégré Universitaires de Santé et de Services Sociaux; Centre for Research on Brain Language and Music; McGill University Health Centre; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Montreal Neurological Institute and Hospital; Douglas College; McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Vetenskapsrådet; Alzheimer's Drug Discovery Foundation; Weston Brain Institute; Consortium canadien en neurodégénérescence associée au vieillissement; Alzheimer's Disease Neuroimaging Initiative; Alzheimer's Association","keywords":"Neurodegeneration; White matter; Atrophy; Brain size; Alzheimer's disease; Neuroimaging; Neurology; Medicine; Magnetic resonance imaging; Psychology; Internal medicine; Alzheimer's Disease Neuroimaging Initiative; Neuropathology; Pathology; Neuroscience; Disease; Radiology","score_opus":0.10477000056938952,"score_gpt":0.39922591817698827,"score_spread":0.29445591760759876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139606263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73692125,0.2476623,0.0000067091723,0.012247064,0.0000866898,0.0015447102,0.00006299171,0.00010195071,0.0013663506],"genre_scores_gemma":[0.98877496,0.009050983,0.00031671178,0.0008222064,0.00028502019,0.0003206907,0.00018815203,0.000102316,0.00013898486],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99368715,0.0011450348,0.00049299834,0.0011012661,0.0019440814,0.0016294674],"domain_scores_gemma":[0.99522036,0.0010275089,0.000049880953,0.0009607008,0.0005385184,0.0022030398],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011206125,0.00040779193,0.0005902759,0.000540983,0.00040607166,0.00018647895,0.00025790828,0.00016348806,0.00065372384],"category_scores_gemma":[0.00049606885,0.00035001617,0.000211082,0.0011742075,0.0007563108,0.0003176122,0.00031845042,0.0012312093,0.00024900906],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016914014,0.009461853,0.5600995,0.00017974545,0.058672,0.05977766,0.0024534832,0.000016652208,0.00471603,0.0027312874,0.022455998,0.26252183],"study_design_scores_gemma":[0.026508845,0.0024565228,0.9259595,0.0006487974,0.0016338953,0.00044688687,0.0010959659,0.0031764677,0.013272974,0.002745068,0.02101618,0.0010388942],"about_ca_topic_score_codex":0.00022585434,"about_ca_topic_score_gemma":0.00004783973,"teacher_disagreement_score":0.36586004,"about_ca_system_score_codex":0.000097095704,"about_ca_system_score_gemma":0.0016482067,"threshold_uncertainty_score":0.99989516},"labels":[],"label_agreement":null},{"id":"W3142417005","doi":"10.1186/s13195-021-00806-7","title":"The efficacy of exergaming in people with major neurocognitive disorder residing in long-term care facilities: a pilot randomized controlled trial","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Koning Boudewijnstichting; KU Leuven; National Institute for Health and Care Research; UK Research and Innovation","keywords":"Randomized controlled trial; Neurocognitive; Physical therapy; Quality of life (healthcare); Physical medicine and rehabilitation; Dementia; Psychology; Memory span; Post-hoc analysis; Medicine; Cognition; Psychiatry","score_opus":0.04544368935981081,"score_gpt":0.37531340296050675,"score_spread":0.32986971360069595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3142417005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95315075,0.029858565,0.000036532398,0.0009068993,0.00005844811,0.013943581,0.000006767528,0.000017117127,0.0020213162],"genre_scores_gemma":[0.9879593,0.007036495,0.000019374578,0.0000482968,0.00007799613,0.0036817745,0.00003812145,0.000042921838,0.001095698],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9921758,0.0038791527,0.0007891468,0.0005557192,0.0016540627,0.0009461066],"domain_scores_gemma":[0.98969406,0.008290719,0.00011529321,0.00045024228,0.0012939062,0.0001557641],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00434166,0.00026884917,0.0013851115,0.00054761174,0.00025439804,0.00012334333,0.00026366403,0.00007300659,0.00035401064],"category_scores_gemma":[0.0021878006,0.0001571342,0.00028764375,0.0013077775,0.0006221598,0.00013320342,0.00013806051,0.00085493276,0.000010363835],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.93221813,0.0012297711,0.038740188,0.000064373635,0.0013632659,0.00023311342,0.006075634,0.0000013733983,0.0013062737,0.000043896165,0.000010035932,0.018713929],"study_design_scores_gemma":[0.90788865,0.003176644,0.0729043,0.0003861585,0.00014309345,0.000008979155,0.010150287,0.000027937333,0.00503767,0.000046700745,0.00007866766,0.00015093577],"about_ca_topic_score_codex":0.0008776688,"about_ca_topic_score_gemma":0.0024424982,"teacher_disagreement_score":0.034808546,"about_ca_system_score_codex":0.00007462587,"about_ca_system_score_gemma":0.0011134105,"threshold_uncertainty_score":0.64077467},"labels":[],"label_agreement":null},{"id":"W3149537993","doi":"10.1186/s13195-021-00808-5","title":"A novel age-informed approach for genetic association analysis in Alzheimer’s disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"H2020 Marie Skłodowska-Curie Actions; National Human Genome Research Institute; National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Genentech; National Institutes of Health; IXICO; H. Lundbeck A/S; Servier; Eisai; Texas Alzheimer's Research and Care Consortium; Northern California Institute for Research and Education; Case Western Reserve University; Pfizer; Biogen; University of Miami; BioClinica; Bristol-Myers Squibb; U.S. Department of Defense; Eli Lilly and Company; F. Hoffmann-La Roche; Vanderbilt University; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; University of Southern California; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Alzheimer's Association; Foundation for the National Institutes of Health; European Commission; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics","keywords":"Logistic regression; Disease; Proportional hazards model; Regression; Genetic association; Regression analysis; Multivariate statistics; Medicine; Demography; Statistics; Biology; Internal medicine; Genotype; Genetics; Single-nucleotide polymorphism; Mathematics; Gene","score_opus":0.12049559954277642,"score_gpt":0.3987981841201408,"score_spread":0.27830258457736434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3149537993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8398733,0.10261723,0.04579966,0.004364301,0.00030284698,0.0037167193,0.00040578836,0.00004735062,0.0028727946],"genre_scores_gemma":[0.960633,0.004673929,0.030072482,0.0006417185,0.00031139175,0.000950047,0.002016558,0.000042458207,0.0006584564],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9972286,0.00050048024,0.00046648429,0.0006246755,0.000408618,0.00077113864],"domain_scores_gemma":[0.998187,0.0003135632,0.00014363143,0.00057489396,0.00057989865,0.00020097749],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018594421,0.00019053668,0.000427307,0.00027105445,0.00018197937,0.00006516312,0.0003028692,0.0002699938,0.000044425207],"category_scores_gemma":[0.0010484759,0.00018167388,0.0003888702,0.0009835456,0.00007397941,0.000006687819,0.000113936294,0.00020951121,0.000007698256],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017752677,0.0025331895,0.74538755,0.000029268962,0.037730873,0.000032258078,0.0009096054,0.01582257,0.102479726,0.00037853408,0.030763531,0.06215765],"study_design_scores_gemma":[0.0046007372,0.00033302436,0.9094005,0.0000070683377,0.0011808113,0.000003141006,0.00041168148,0.00887098,0.006530236,0.0006278716,0.06743051,0.0006033938],"about_ca_topic_score_codex":0.00017272019,"about_ca_topic_score_gemma":0.000417067,"teacher_disagreement_score":0.16401301,"about_ca_system_score_codex":0.00006981499,"about_ca_system_score_gemma":0.00059578486,"threshold_uncertainty_score":0.74084455},"labels":[],"label_agreement":null},{"id":"W3159282112","doi":"10.1186/s13195-021-00830-7","title":"Investigating the relationship between BMI across adulthood and late life brain pathologies","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Avid Radiopharmaceuticals; Dementias Platform UK; UK Dementia Research Institute; Alzheimer’s Research UK; Brain Research Trust; Wolfson Foundation; University College London Hospitals NHS Foundation Trust; European Commission; Medical Research Foundation; National Institute for Health and Care Research; Wellcome Trust; Alzheimer's Society; California State University, Bakersfield; Brain Research UK; Weston Brain Institute; Medical Research Council; Biogen; Engineering and Physical Sciences Research Council; Eli Lilly and Company","keywords":"Medicine; Overweight; Body mass index; Dementia; Hyperintensity; Internal medicine; Confidence interval; Odds ratio; Cohort; Magnetic resonance imaging; Disease; Radiology","score_opus":0.27270597182488177,"score_gpt":0.4700482669007718,"score_spread":0.19734229507589002,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159282112","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93688905,0.013859933,0.00003289139,0.04733875,0.000028926612,0.0007608829,0.000016092457,0.00005819033,0.0010153065],"genre_scores_gemma":[0.995067,0.0010595017,0.000318189,0.0020837232,0.00023327209,0.0001557227,0.000056173063,0.00003385879,0.0009925464],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9958688,0.001470088,0.00029297726,0.00046301336,0.0010767186,0.00082841114],"domain_scores_gemma":[0.9939358,0.0044315625,0.00005092061,0.000512453,0.0006900545,0.00037918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0041597425,0.00016674677,0.0002552418,0.00010554684,0.00090602477,0.00025779323,0.0002172672,0.00012135273,0.0001514276],"category_scores_gemma":[0.00551823,0.0001111137,0.00008440239,0.0008419211,0.00085603725,0.00017361129,0.0003268408,0.0011341684,0.0000898345],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062696505,0.000071876944,0.92519194,0.000019876712,0.00038514833,0.00005182194,0.0028244804,1.8352485e-7,0.0038874531,0.00025737134,0.0017158507,0.065531306],"study_design_scores_gemma":[0.0016823097,0.0004355006,0.9796534,0.00008044275,0.000038119917,0.00002267513,0.0037982906,0.00001844863,0.00498698,0.0037852987,0.0053818678,0.000116653035],"about_ca_topic_score_codex":0.00006300704,"about_ca_topic_score_gemma":0.000014667001,"teacher_disagreement_score":0.06541465,"about_ca_system_score_codex":0.000020531535,"about_ca_system_score_gemma":0.00047779645,"threshold_uncertainty_score":0.6968502},"labels":[],"label_agreement":null},{"id":"W3160240799","doi":"10.1186/s13195-021-00842-3","title":"Repurposing beta-3 adrenergic receptor agonists for Alzheimer’s disease: beneficial effects in a mouse model","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval","funders":"Canadian Institutes of Health Research; Alzheimer Society Research Program; Alzheimer Society; Réseau québécois de recherche sur le vieillissement","keywords":"Agonist; Internal medicine; Endocrinology; Stimulation; Medicine; Genetically modified mouse; Brown adipose tissue; Receptor; Neuroscience; Biology; Transgene; Adipose tissue","score_opus":0.12832837090065136,"score_gpt":0.4026352010122983,"score_spread":0.27430683011164697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3160240799","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5056815,0.48492077,0.0004646482,0.003825847,0.00038586403,0.0037834786,0.000104362,0.000147728,0.00068580144],"genre_scores_gemma":[0.9538046,0.023103584,0.011572244,0.0018776382,0.0017141708,0.002018005,0.00064186053,0.00032870553,0.0049391533],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99588275,0.00043125587,0.00050384516,0.0009308843,0.001043282,0.0012079843],"domain_scores_gemma":[0.99709535,0.00046061413,0.00007832275,0.0010023634,0.0006884889,0.0006748574],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001139362,0.0003647657,0.0007372083,0.00040157736,0.00032465765,0.000100603815,0.00030225972,0.00022648301,0.00015867015],"category_scores_gemma":[0.00027020916,0.0003319217,0.00033914857,0.000746533,0.00019898971,0.00021299845,0.00012690951,0.0006665652,0.00006689597],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009286222,0.0030933225,0.0018269556,0.00021161266,0.0047825123,0.0007031832,0.0029635327,0.00068091945,0.365582,0.015002344,0.012513079,0.5833543],"study_design_scores_gemma":[0.012348915,0.0009990031,0.0032903026,0.00037221753,0.00116335,0.000028545057,0.00016493547,0.00878473,0.7269058,0.004123415,0.24087407,0.0009446907],"about_ca_topic_score_codex":0.00014985913,"about_ca_topic_score_gemma":0.00005413234,"teacher_disagreement_score":0.5824096,"about_ca_system_score_codex":0.00006914779,"about_ca_system_score_gemma":0.001185708,"threshold_uncertainty_score":0.9999133},"labels":[],"label_agreement":null},{"id":"W3160870314","doi":"10.1186/s13195-021-00836-1","title":"Validation of amyloid PET positivity thresholds in centiloids: a multisite PET study approach","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":234,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; BioClinica; F. Hoffmann-La Roche; University of Southern California; Biogen; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; National Institute on Aging; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Positron emission tomography; Neuroimaging; Nuclear medicine; Neurology; Dementia; Binding potential; White matter; Pipeline (software); Psychology; Medicine; Medical physics; Computer science; Neuroscience; Pathology; Magnetic resonance imaging; Disease; Radiology","score_opus":0.10850531688605661,"score_gpt":0.4166184408711215,"score_spread":0.30811312398506485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3160870314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988187,0.003176238,0.00007567734,0.00041006217,0.000053267297,0.0026366955,0.000016403092,0.000028300565,0.0054163584],"genre_scores_gemma":[0.99686545,0.0014761837,0.0005519999,0.00007918598,0.00009166648,0.00026483103,0.00013702895,0.00004119344,0.0004924346],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99383813,0.0021269585,0.00052096305,0.00071227807,0.00202766,0.0007740038],"domain_scores_gemma":[0.9974911,0.0002975164,0.000071778915,0.00069976295,0.0011950952,0.0002447098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0047676945,0.00021403824,0.0005131421,0.0005882013,0.00014602962,0.00009193584,0.000258882,0.00004820757,0.0006439996],"category_scores_gemma":[0.00016885383,0.00018661922,0.00017321839,0.0015555795,0.0002627052,0.0002521563,0.00023586609,0.0007877111,0.00005306816],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013829219,0.011313551,0.86225516,0.000039165618,0.0012511746,0.0008484226,0.001251835,0.000002401813,0.09845743,0.000050637256,0.00025647957,0.022890849],"study_design_scores_gemma":[0.0076888255,0.001863807,0.84082305,0.000070024165,0.00009099006,0.00011040574,0.0034747475,0.00019316518,0.14503773,0.00007227301,0.00039847358,0.00017651514],"about_ca_topic_score_codex":0.0006288973,"about_ca_topic_score_gemma":0.00006955858,"teacher_disagreement_score":0.0465803,"about_ca_system_score_codex":0.00006365896,"about_ca_system_score_gemma":0.00037005797,"threshold_uncertainty_score":0.76101106},"labels":[],"label_agreement":null},{"id":"W3164718964","doi":"10.1186/s13195-021-00848-x","title":"Correlating natural language processing and automated speech analysis with clinician assessment to quantify speech-language changes in mild cognitive impairment and Alzheimer’s dementia","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Toronto Rehabilitation Institute; University of Toronto","funders":"National Institute on Deafness and Other Communication Disorders; National Institute on Aging; National Institutes of Health; Carnegie Mellon University; University of Pittsburgh","keywords":"Perseveration; Dementia; Psychology; Cognition; Terminology; Correlation; Audiology; Cognitive psychology; Natural language processing; Computer science; Linguistics; Disease; Medicine; Pathology","score_opus":0.08032911195987817,"score_gpt":0.455078454064828,"score_spread":0.3747493421049498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164718964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9128808,0.08217461,0.000053505035,0.0021405276,0.000034837696,0.002050384,0.000023254204,0.00011564562,0.0005264361],"genre_scores_gemma":[0.99334687,0.0016573208,0.0034038972,0.0008566115,0.00009201438,0.00023867714,0.00021642703,0.000061836894,0.00012634537],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9949495,0.0008119555,0.00046643295,0.0010438125,0.0015836139,0.0011446534],"domain_scores_gemma":[0.9977291,0.00048464295,0.000113716495,0.00035566933,0.00083847286,0.00047837183],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0025348198,0.0003817088,0.0007061925,0.0012237624,0.00034568296,0.00033637305,0.00015940206,0.00013474072,0.00036661274],"category_scores_gemma":[0.00012487863,0.00030534578,0.00009661471,0.0029987465,0.00030928606,0.00021815223,0.00029558456,0.001004964,0.00001541717],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017138983,0.0008879213,0.5063838,0.00006743774,0.012253499,0.0019978024,0.006670474,0.000002054241,0.010675059,0.0000046609966,0.00010963347,0.4592338],"study_design_scores_gemma":[0.006469566,0.0029313373,0.90487814,0.0006740503,0.0028373038,0.00013029852,0.031061621,0.012182708,0.038223237,0.0000063430057,0.00013246365,0.0004729496],"about_ca_topic_score_codex":0.00087173586,"about_ca_topic_score_gemma":0.00277652,"teacher_disagreement_score":0.45876083,"about_ca_system_score_codex":0.00006502188,"about_ca_system_score_gemma":0.0004799843,"threshold_uncertainty_score":0.99993986},"labels":[],"label_agreement":null},{"id":"W3172159521","doi":"10.1186/s13195-021-00852-1","title":"GPS driving: a digital biomarker for preclinical Alzheimer disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Older Adults Driving Studies","field":"Health Professions","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Rehabilitation Institute; University of Toronto","funders":"National Institute on Aging; BrightFocus Foundation; Foundation for the National Institutes of Health","keywords":"Medicine; Biomarker; Dementia; Neurology; Receiver operating characteristic; Disease; Oncology; Internal medicine; Psychiatry","score_opus":0.4515470179885745,"score_gpt":0.5642669874717421,"score_spread":0.11271996948316759,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3172159521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.53118014,0.25691968,0.0014673637,0.14439914,0.0067190123,0.022459364,0.0011635403,0.0017988122,0.03389294],"genre_scores_gemma":[0.9846468,0.0030159678,0.00061904686,0.0015007952,0.0011952842,0.0027574375,0.00016451304,0.00019387006,0.0059062666],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9931268,0.0016449797,0.00089789246,0.0011353487,0.0012070166,0.0019879676],"domain_scores_gemma":[0.9873718,0.008392801,0.00015168764,0.0013471503,0.001965291,0.00077127543],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0025472145,0.00038749605,0.0005852141,0.0002334967,0.0021041427,0.00016355199,0.0006877512,0.00027561182,0.0011587176],"category_scores_gemma":[0.0033999928,0.0003206495,0.00039073912,0.00078647403,0.00055998814,0.0004618005,0.00074087235,0.0012703871,0.0010166044],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010214275,0.0014978994,0.48568383,0.00008860697,0.0062268907,0.000117413205,0.004136665,0.0000014417303,0.00072517985,0.0012438539,0.33827358,0.16098322],"study_design_scores_gemma":[0.0033348047,0.00025261065,0.2792709,0.00028301866,0.00019047028,0.0000020812818,0.0013487613,0.00019643323,0.00034057614,0.0045742746,0.7097185,0.00048753127],"about_ca_topic_score_codex":0.00005091483,"about_ca_topic_score_gemma":0.0001703107,"teacher_disagreement_score":0.45346665,"about_ca_system_score_codex":0.00007384457,"about_ca_system_score_gemma":0.001557207,"threshold_uncertainty_score":0.99992454},"labels":[],"label_agreement":null},{"id":"W3175629638","doi":"10.1186/s13195-021-00886-5","title":"Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Olav Thon Stiftelsen; Vetenskapsrådet; National Institute on Aging; Knut och Alice Wallenbergs Stiftelse; Hjärnfonden; Canadian Institutes of Health Research; EU Joint Programme – Neurodegenerative Disease Research; Familjen Erling-Perssons Stiftelse; Chalmers Tekniska Högskola; Alzheimer's Drug Discovery Foundation","keywords":"Cohort; Medicine; Disease; Pathological; Alzheimer's Disease Neuroimaging Initiative; Neuropsychology; Internal medicine; Cognition; Cognitive decline; Dementia; Demographics; Neuroimaging; Amyloid (mycology); Pathology; Oncology; Psychiatry; Demography","score_opus":0.05440518038918191,"score_gpt":0.40057674555371114,"score_spread":0.34617156516452924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175629638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9693008,0.024183394,0.000020759317,0.0022021523,0.00002972019,0.0025433695,0.000046099925,0.0000406422,0.0016330632],"genre_scores_gemma":[0.9965096,0.0016135542,0.00020349391,0.0006403074,0.00010234169,0.00041770076,0.00034341574,0.00005807056,0.00011152085],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99535,0.0007598421,0.00031715934,0.00078491925,0.0018621802,0.0009258998],"domain_scores_gemma":[0.99649876,0.00058388984,0.00006055621,0.00029554506,0.0018929896,0.00066826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010676581,0.00026665896,0.00034880167,0.00038071163,0.00029756248,0.00013820811,0.0001258828,0.000089936286,0.00035311823],"category_scores_gemma":[0.00032518164,0.00019811226,0.000066858345,0.0009926747,0.00051984214,0.0002947418,0.0002996506,0.0007845349,0.000032160035],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006618919,0.0017959946,0.8242095,0.000017024788,0.0008889088,0.00051298464,0.00039347596,2.0795459e-7,0.00028518453,0.000020438205,0.000054464694,0.16520292],"study_design_scores_gemma":[0.010552689,0.0023487895,0.97368413,0.0006906162,0.00025756352,0.0000108986505,0.0005738793,0.00015595891,0.010753584,0.00013261485,0.000626773,0.0002124878],"about_ca_topic_score_codex":0.00009207627,"about_ca_topic_score_gemma":0.000062441075,"teacher_disagreement_score":0.16499043,"about_ca_system_score_codex":0.000037938513,"about_ca_system_score_gemma":0.0006576182,"threshold_uncertainty_score":0.8078784},"labels":[],"label_agreement":null},{"id":"W3188554627","doi":"10.1186/s13195-021-00872-x","title":"Developing methods to detect and diagnose chronic traumatic encephalopathy during life: rationale, design, and methodology for the DIAGNOSE CTE Research Project","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Traumatic Brain Injury Research","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute on Aging; Clinical and Translational Science Institute, Boston University; University of California, San Diego; National Institutes of Health; Grifols; Eisai; Genentech; University of Oxford; National Institute of Neurological Disorders and Stroke; University of Cambridge; Agios Pharmaceuticals; National Institute of General Medical Sciences; H. Lundbeck A/S; Sunovion; University of Washington; Patient-Centered Outcomes Research Institute; School of Medicine, Boston University; Eli Lilly and Company; U.S. Department of Defense; George Washington University; Allergan; National Operating Committee on Standards for Athletic Equipment; York University; Pfizer; Biogen; Novo Nordisk; Massachusetts General Hospital; National Collegiate Athletic Association; Cleveland Clinic; Brigham and Women's Hospital; Amgen","keywords":"Chronic traumatic encephalopathy; Medicine; Traumatic brain injury; Neuroimaging; Concussion; Neuropsychology; Physical therapy; Physical medicine and rehabilitation; Poison control; Psychiatry; Cognition; Emergency medicine; Injury prevention","score_opus":0.7140558873293122,"score_gpt":0.5850251497549139,"score_spread":0.1290307375743983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3188554627","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.35752022,0.29153204,0.2790793,0.04569083,0.00025474207,0.025628563,0.000025271625,0.00015287905,0.00011616168],"genre_scores_gemma":[0.09599444,0.036602333,0.8504283,0.0008206587,0.000692399,0.014825497,0.000017661785,0.00018087981,0.0004378738],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9834753,0.011476953,0.00066463853,0.0011238259,0.0015989253,0.001660342],"domain_scores_gemma":[0.9290649,0.06737062,0.000070943366,0.0010388894,0.0019005988,0.0005540298],"candidate_categories":["metaresearch","metaepi_narrow","sts"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.031872462,0.0003453245,0.0007260504,0.0009319173,0.0014711863,0.00033725903,0.0005520313,0.00023557333,0.00016171052],"category_scores_gemma":[0.020631954,0.00024733963,0.000119892706,0.0023551856,0.0010284284,0.00022650324,0.00052607525,0.0014660375,0.000022412554],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025229556,0.00014655308,0.0003753855,0.00047677566,0.0020723569,0.00015697702,0.010991904,0.000017376311,0.0984136,0.0014816425,0.0028396999,0.8805048],"study_design_scores_gemma":[0.014555983,0.008128242,0.10647255,0.0012669137,0.0003815537,0.0010240686,0.01263205,0.0034625065,0.7691783,0.02363004,0.058015097,0.0012527446],"about_ca_topic_score_codex":0.00021936231,"about_ca_topic_score_gemma":0.00013107015,"teacher_disagreement_score":0.879252,"about_ca_system_score_codex":0.00026240494,"about_ca_system_score_gemma":0.004139845,"threshold_uncertainty_score":0.9999979},"labels":[],"label_agreement":null},{"id":"W3195883521","doi":"10.1186/s13195-021-00881-w","title":"Visuospatial alpha and gamma oscillations scale with the severity of cognitive dysfunction in patients on the Alzheimer’s disease spectrum","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute on Aging; National Institutes of Health; Foundation for the National Institutes of Health","keywords":"Magnetoencephalography; Audiology; Neurocognitive; Biomarker; Cognition; Psychology; Neuroscience; Alpha (finance); Neural correlates of consciousness; Electroencephalography; Medicine; Developmental psychology; Psychometrics; Biology","score_opus":0.10058221955433361,"score_gpt":0.33669492551857766,"score_spread":0.23611270596424405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195883521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96514714,0.0011281753,0.000024066583,0.031713046,0.000103176804,0.0010856632,0.00006473204,0.000018985374,0.00071502605],"genre_scores_gemma":[0.99762183,0.0003571759,0.000005086613,0.0017064703,0.00007219686,0.00016105735,0.000007129257,0.000021529862,0.00004752652],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99652743,0.0012932667,0.00016579035,0.00056074845,0.0010807307,0.0003720534],"domain_scores_gemma":[0.9893553,0.009777155,0.000068669215,0.00037424162,0.0003356796,0.00008895249],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072323694,0.00016854407,0.00017034628,0.000121367644,0.0007127106,0.00007820826,0.00019101406,0.000037264024,0.0001183036],"category_scores_gemma":[0.0020169956,0.0000967578,0.000052474974,0.00095619075,0.0009186957,0.00018446488,0.0001537915,0.00044671117,0.000019693927],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02686827,0.0066829235,0.7324827,0.000026410573,0.0023766088,0.00012527082,0.013067006,0.00039179422,0.008976068,0.0101947645,0.015342322,0.18346587],"study_design_scores_gemma":[0.0018287068,0.0009226532,0.9420362,0.000054368258,0.00005522186,0.0000027453154,0.0006133446,0.00034242222,0.050863642,0.0013353677,0.001770021,0.00017528284],"about_ca_topic_score_codex":0.00019734852,"about_ca_topic_score_gemma":0.0005409139,"teacher_disagreement_score":0.20955354,"about_ca_system_score_codex":0.000029228071,"about_ca_system_score_gemma":0.00018891545,"threshold_uncertainty_score":0.5481666},"labels":[],"label_agreement":null},{"id":"W3198822531","doi":"10.1186/s13195-021-00892-7","title":"Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer’s dementia","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; University of Ottawa; Health Sciences Centre; Canada Research Chairs; Heart and Stroke Foundation; Sunnybrook Health Science Centre; Toronto Rehabilitation Institute; University of Toronto; University of New Brunswick","funders":"National Institute on Aging; Canadian Institutes of Health Research; Weston Brain Institute; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada; National Institutes of Health; Alzheimer's Association","keywords":"Dementia; Cognition; Memory span; Alzheimer's disease; Audiology; Psychology; Cognitive reserve; Cognitive decline; Wechsler Memory Scale; Cognitive test; Wechsler Adult Intelligence Scale; Medicine; Working memory; Psychiatry; Cognitive impairment; Internal medicine; Disease","score_opus":0.11289942898982902,"score_gpt":0.3991596965284643,"score_spread":0.28626026753863526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198822531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9196888,0.07331132,0.00006186429,0.0027831595,0.00008197211,0.002602596,0.00020288762,0.00005795929,0.001209433],"genre_scores_gemma":[0.967608,0.028173752,0.0003730161,0.002056865,0.00018989279,0.000489195,0.00079733407,0.000087192166,0.0002247672],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.993957,0.0011947963,0.0006662368,0.0011941376,0.0015348246,0.0014529965],"domain_scores_gemma":[0.99466664,0.0015101836,0.00010602563,0.00031531262,0.002636637,0.0007651788],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0022413223,0.0004727666,0.000645729,0.00072243554,0.0005781166,0.00048809047,0.00015509909,0.00023150854,0.0017111433],"category_scores_gemma":[0.00059146,0.00044465926,0.00013359368,0.0013572287,0.0012493097,0.0007789424,0.00053565355,0.0011269224,0.00012337185],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011533422,0.003309718,0.8259193,0.000072620714,0.01171974,0.0010125594,0.0015659563,8.287299e-8,0.016930392,0.000108234766,0.0019173486,0.12591065],"study_design_scores_gemma":[0.024995178,0.0034122402,0.7794762,0.0006610234,0.0015595462,0.00026891843,0.004186205,0.0000688816,0.17721897,0.00032159765,0.0072086635,0.0006225242],"about_ca_topic_score_codex":0.0004796865,"about_ca_topic_score_gemma":0.0003059129,"teacher_disagreement_score":0.16028857,"about_ca_system_score_codex":0.0000383088,"about_ca_system_score_gemma":0.0007641326,"threshold_uncertainty_score":0.9998005},"labels":[],"label_agreement":null},{"id":"W3199278731","doi":"10.1186/s13195-021-00894-5","title":"Is comprehensiveness critical? Comparing short and long format cognitive assessments in preclinical Alzheimer disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute on Aging; National Institutes of Health","keywords":"Geriatric psychiatry; Neurology; Disease; Cognition; Medicine; Cognitive aging; Psychology; Psychiatry; Internal medicine","score_opus":0.33573232363152494,"score_gpt":0.5431792612770401,"score_spread":0.20744693764551514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199278731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9385835,0.052708287,0.00024787302,0.0041830186,0.00010270583,0.0017655602,0.000027428141,0.000046048255,0.0023355712],"genre_scores_gemma":[0.9912464,0.005776966,0.00014864287,0.0020479865,0.00011948859,0.0003290588,0.00012576279,0.000053928885,0.00015174424],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9945708,0.0010784337,0.0005464239,0.00089123205,0.001732026,0.001181087],"domain_scores_gemma":[0.9951054,0.0017282966,0.000028873157,0.0004676073,0.0017581687,0.0009116657],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016187202,0.00029848987,0.0006078766,0.0003732122,0.00030498143,0.0002398466,0.00020548826,0.00013202403,0.0013538786],"category_scores_gemma":[0.00040080966,0.00024368134,0.00016333998,0.0007528499,0.00081363495,0.00043484033,0.00045028687,0.0011294166,0.000102023645],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029306167,0.0017835796,0.8825187,0.00007427114,0.0015045279,0.0012057035,0.00030638278,2.7703675e-7,0.0005622281,0.00010293096,0.00049805944,0.108512715],"study_design_scores_gemma":[0.004776191,0.0007401647,0.97872454,0.0005656427,0.00036669857,0.000055695324,0.0008950334,0.0012028397,0.008974955,0.0004601881,0.002937718,0.00030031768],"about_ca_topic_score_codex":0.000049273254,"about_ca_topic_score_gemma":0.000024456558,"teacher_disagreement_score":0.1082124,"about_ca_system_score_codex":0.000046808327,"about_ca_system_score_gemma":0.0006632489,"threshold_uncertainty_score":0.99955904},"labels":[],"label_agreement":null},{"id":"W3199867646","doi":"10.1186/s13195-021-00896-3","title":"Impact of an educational programme on Alzheimer’s disease patients’ quality of life: results of the randomized controlled trial THERAD","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Direction de l’hospitalisation et de l’offre de Soins; Direction Générale de l’offre de Soins; Université de Toulouse; Health Research Foundation","keywords":"Medicine; Quality of life (healthcare); Psychological intervention; Randomized controlled trial; Caregiver burden; Intervention (counseling); Physical therapy; Disease; Dementia; Pediatrics; Internal medicine; Psychiatry","score_opus":0.1491162463914307,"score_gpt":0.47059789234900684,"score_spread":0.3214816459575761,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199867646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9782618,0.0064454186,0.000001709696,0.0025652212,0.00013326011,0.010747815,0.00012904477,0.0000096617005,0.0017060202],"genre_scores_gemma":[0.9975022,0.0007203163,0.00005053485,0.00010330588,0.00017850303,0.000959818,0.00020181303,0.000031641066,0.00025187264],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9875796,0.006915296,0.0014242434,0.00047116823,0.0030171215,0.0005925869],"domain_scores_gemma":[0.98985165,0.004030871,0.00056785106,0.0010824085,0.00394729,0.0005199132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007897369,0.00025179077,0.0015336031,0.00027349676,0.00013160463,0.000034541183,0.00041374553,0.00009543272,0.00085267506],"category_scores_gemma":[0.005952823,0.00013458393,0.0013706966,0.00079921196,0.0010110252,0.00011369879,0.00010248339,0.00046016468,0.000006600673],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9267099,0.0137005765,0.027674256,0.000020991467,0.008128956,0.0000016535521,0.0004184752,0.0000015275943,0.0016270118,0.00033319235,0.00035450087,0.02102898],"study_design_scores_gemma":[0.73208517,0.0042047943,0.25718093,0.000073138785,0.00038647445,2.7699662e-7,0.00010267838,0.00004165865,0.0051049856,0.00064479024,0.00007782742,0.00009727742],"about_ca_topic_score_codex":0.00067402906,"about_ca_topic_score_gemma":0.000013165264,"teacher_disagreement_score":0.22950667,"about_ca_system_score_codex":0.000043522952,"about_ca_system_score_gemma":0.0043265554,"threshold_uncertainty_score":0.9336194},"labels":[],"label_agreement":null},{"id":"W3202168364","doi":"10.1186/s13195-021-00906-4","title":"BMI1 is associated with CSF amyloid-β and rates of cognitive decline in Alzheimer’s disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; U.S. National Library of Medicine; IXICO; National Institute of General Medical Sciences; H. Lundbeck A/S; Servier; Eisai; Korea Health Industry Development Institute; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; National Institute on Aging; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Minor allele frequency; Single-nucleotide polymorphism; Cognitive decline; Biomarker; Alzheimer's disease; Oncology; Allele; Internal medicine; Medicine; Genetic association; Disease; Dementia; Genetics; Genotype; Biology; Gene","score_opus":0.12648769273754884,"score_gpt":0.4237787673247108,"score_spread":0.297291074587162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202168364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7691016,0.22521523,0.0000027626547,0.0032658924,0.000017536582,0.0013712135,0.00020940397,0.000031957778,0.0007844134],"genre_scores_gemma":[0.9855562,0.012746329,0.00008176288,0.000739509,0.0000582001,0.00024980138,0.00040762412,0.00007678723,0.00008381383],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9953013,0.00078366115,0.00043987334,0.00078775367,0.0016800788,0.001007334],"domain_scores_gemma":[0.9951594,0.0013657189,0.00010299071,0.00054681354,0.0017858765,0.001039184],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009439331,0.0003484846,0.0006811838,0.00044611114,0.00019373807,0.00008181825,0.00018014021,0.00013635278,0.0007153668],"category_scores_gemma":[0.0006250569,0.00026635744,0.00014497085,0.001473759,0.0008523628,0.00025055616,0.00020369444,0.0006246803,0.000052322095],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016462816,0.0071228878,0.8633168,0.00004232477,0.062412698,0.005860154,0.0014161487,0.0000013034088,0.00075027085,0.00013499962,0.0014673879,0.041012213],"study_design_scores_gemma":[0.020238,0.0025221768,0.9294402,0.0010570454,0.0018184835,0.0000420555,0.0010879514,0.00023389272,0.04124895,0.0012502604,0.000596147,0.00046485176],"about_ca_topic_score_codex":0.00044512784,"about_ca_topic_score_gemma":0.00016163103,"teacher_disagreement_score":0.21645458,"about_ca_system_score_codex":0.000053861586,"about_ca_system_score_gemma":0.0016736261,"threshold_uncertainty_score":0.99997884},"labels":[],"label_agreement":null},{"id":"W3206207241","doi":"10.1186/s13195-021-00916-2","title":"Characterization of an APP/tau rat model of Alzheimer’s disease by positron emission tomography and immunofluorescent labeling","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Österreichische Forschungsförderungsgesellschaft","keywords":"Positron emission tomography; Neurology; Brain positron emission tomography; Neuroscience; Medicine; Geriatric psychiatry; Pathology; Psychology; Preclinical imaging; Psychiatry; Biology","score_opus":0.06457565185301073,"score_gpt":0.36256903086119235,"score_spread":0.2979933790081816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3206207241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83142453,0.16662003,0.00003840391,0.0005278385,0.00003114733,0.0010421484,0.00021875204,0.000036828736,0.000060321123],"genre_scores_gemma":[0.97802234,0.019785063,0.0004724339,0.000088345536,0.000052641313,0.00010590411,0.0013614419,0.000069924696,0.000041882442],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99618787,0.0005195461,0.00050833996,0.00063859206,0.0014680838,0.00067756063],"domain_scores_gemma":[0.99684846,0.00009054127,0.00013522364,0.0008347659,0.0011035618,0.0009874138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064452854,0.0002925991,0.0005261184,0.0003711912,0.00023310205,0.000055002347,0.00020276185,0.00012967423,0.00010771725],"category_scores_gemma":[0.000049871272,0.00024513877,0.00019662706,0.0007045323,0.00039809098,0.00034994908,0.00015110857,0.00037142026,0.000004985693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036617047,0.0025479072,0.0068241395,0.00006732354,0.007271786,0.00006751213,0.0003967367,0.000004429924,0.9495335,0.000053629596,0.0002284864,0.029342806],"study_design_scores_gemma":[0.00402437,0.0010236541,0.010832636,0.00026200918,0.0008969042,0.000008371081,0.00016146124,0.0037915315,0.97830844,0.00023637127,0.00021034374,0.00024389404],"about_ca_topic_score_codex":0.00011352783,"about_ca_topic_score_gemma":0.000001555224,"teacher_disagreement_score":0.14683497,"about_ca_system_score_codex":0.00003059998,"about_ca_system_score_gemma":0.000750591,"threshold_uncertainty_score":0.99964696},"labels":[],"label_agreement":null},{"id":"W3207243873","doi":"10.1186/s13195-021-00913-5","title":"Age, vascular disease, and Alzheimer’s disease pathologies in amyloid negative elderly adults","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Alzheimer's Disease Neuroimaging Initiative","keywords":"Internal medicine; Neurodegeneration; Medicine; Cognitive decline; Alzheimer's disease; Atrophy; Neurology; Amyloid (mycology); Hyperintensity; Apolipoprotein E; Endocrinology; Psychology; Disease; Dementia; Pathology; Cardiology; Psychiatry; Magnetic resonance imaging","score_opus":0.08607405695023236,"score_gpt":0.3891178339853605,"score_spread":0.30304377703512814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3207243873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8618309,0.12954871,0.0000144255055,0.0047798934,0.000057909652,0.0019405454,0.00003541678,0.000071692666,0.001720487],"genre_scores_gemma":[0.96398276,0.033640247,0.00026125996,0.00065069215,0.00014041245,0.0006362656,0.00013736941,0.00005959502,0.00049139396],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9946034,0.0011986241,0.00036732788,0.0009947066,0.0016749956,0.0011609598],"domain_scores_gemma":[0.9967454,0.0005352876,0.00004274389,0.0007710815,0.0008824988,0.00102297],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012957437,0.00032618514,0.0004559685,0.0004843502,0.00027051003,0.0001956713,0.00026407882,0.000102849845,0.0007750124],"category_scores_gemma":[0.00066832924,0.0002728941,0.00020239178,0.0010940686,0.0007713987,0.00029584006,0.00032059077,0.00086346676,0.00010932872],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011209461,0.0043410314,0.41962016,0.000149129,0.0038451022,0.018232375,0.0025348035,0.0000022854024,0.005842566,0.0006650305,0.0027054327,0.5308526],"study_design_scores_gemma":[0.00605687,0.0012191924,0.9762514,0.0002868035,0.00025970797,0.000015771291,0.0014555574,0.00008190828,0.0043194043,0.00329336,0.006448359,0.00031165266],"about_ca_topic_score_codex":0.00017023995,"about_ca_topic_score_gemma":0.000047196037,"teacher_disagreement_score":0.55663127,"about_ca_system_score_codex":0.00004593712,"about_ca_system_score_gemma":0.00081065646,"threshold_uncertainty_score":0.99997234},"labels":[],"label_agreement":null},{"id":"W3209596180","doi":"10.1186/s13195-021-00919-z","title":"Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer’s disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Ministry of Science and ICT, South Korea; National Center for Advancing Translational Sciences; Seoul National University; U.S. National Library of Medicine; National Institute on Aging; National Research Foundation; Canadian Institutes of Health Research; National Institute for Health and Care Research; National Research Foundation of Korea; Seoul National University Bundang Hospital","keywords":"Expression quantitative trait loci; Quantitative trait locus; Biology; Genome-wide association study; Transcriptome; Genetic association; Gene; Gene expression; Genetics; Single-nucleotide polymorphism; Genotype","score_opus":0.07727311238879934,"score_gpt":0.35976968884958355,"score_spread":0.2824965764607842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209596180","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8861288,0.110665515,0.000004289362,0.0016028439,0.000016420368,0.0013041742,0.00010675828,0.000036442183,0.00013479014],"genre_scores_gemma":[0.99737424,0.0016337367,0.00021040777,0.00016246983,0.000044349636,0.00022589495,0.00023830963,0.00007700837,0.000033571112],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99498725,0.0012677995,0.00048648738,0.0007960715,0.0014920755,0.00097030716],"domain_scores_gemma":[0.99742043,0.0004309338,0.00012704547,0.0006202659,0.00065566885,0.00074566185],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007290827,0.0003505387,0.0006475874,0.00057669764,0.00016903352,0.00007217367,0.00017584428,0.00018651168,0.00028657544],"category_scores_gemma":[0.0002164289,0.0002811082,0.00012787517,0.0015573915,0.0004688485,0.00029925807,0.00013088428,0.0006631659,0.0000064010546],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018926825,0.013140957,0.78855294,0.00011958147,0.030700669,0.015758332,0.0019647111,0.000070912116,0.104085095,0.0000935772,0.0005713254,0.026015056],"study_design_scores_gemma":[0.016163109,0.0013968569,0.8969208,0.0011984595,0.00053937646,0.00003877139,0.00046904085,0.0003651029,0.08223843,0.0003019814,0.000031190808,0.00033685158],"about_ca_topic_score_codex":0.0003337192,"about_ca_topic_score_gemma":0.00030806096,"teacher_disagreement_score":0.11124548,"about_ca_system_score_codex":0.00010281553,"about_ca_system_score_gemma":0.0008568876,"threshold_uncertainty_score":0.9999641},"labels":[],"label_agreement":null},{"id":"W3210878663","doi":"10.1186/s13195-021-00921-5","title":"The apolipoprotein receptor LRP3 compromises APP levels","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Universitat de Barcelona; Ministerio de Economía y Competitividad; Universität Wien; Medizinische Universität Wien; Georgetown University; Université de Sherbrooke; European Regional Development Fund; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; Generalitat Valenciana; University of Nebraska Medical Center","keywords":"Reelin; Low-density lipoprotein receptor-related protein 8; Western blot; Amyloid precursor protein; Receptor; Blot; Biology; Molecular biology; Internal medicine; Endocrinology; Cell biology; Alzheimer's disease; Medicine; Lipoprotein; Genetics; Gene; Very low-density lipoprotein; Cholesterol","score_opus":0.18602975278755976,"score_gpt":0.4255492418361751,"score_spread":0.23951948904861534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210878663","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.25391382,0.68724793,0.000031253214,0.033551447,0.0003833395,0.0054603703,0.00019007837,0.00034909928,0.018872643],"genre_scores_gemma":[0.9747282,0.018906174,0.0006621882,0.0005380087,0.00070641364,0.0009209274,0.00015242095,0.00012365477,0.0032619874],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9941629,0.0009995709,0.0003846824,0.000716856,0.0022186546,0.0015173277],"domain_scores_gemma":[0.99540526,0.0008455974,0.00005972289,0.0014225595,0.0013410605,0.0009258113],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0014060133,0.00032124686,0.00042627405,0.00017388337,0.0012879142,0.00029603933,0.00049024005,0.000149511,0.0018477966],"category_scores_gemma":[0.0003045117,0.00020344148,0.00029593127,0.001007457,0.0008287277,0.00017406908,0.0002467959,0.0009224471,0.0018800033],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0066172183,0.0042243986,0.0062994733,0.00006289295,0.08058121,0.0016695572,0.0008672379,0.0000014068274,0.035083383,0.004353333,0.12231576,0.7379241],"study_design_scores_gemma":[0.010249926,0.0019701738,0.023386518,0.00019194718,0.0004121623,0.0001555165,0.0011790682,0.0000823645,0.33302116,0.0038302552,0.62492573,0.00059513916],"about_ca_topic_score_codex":0.00033222153,"about_ca_topic_score_gemma":0.000035699682,"teacher_disagreement_score":0.737329,"about_ca_system_score_codex":0.00011390636,"about_ca_system_score_gemma":0.0016892109,"threshold_uncertainty_score":0.9990646},"labels":[],"label_agreement":null},{"id":"W3212409089","doi":"10.1186/s13195-021-00910-8","title":"Boosting the diagnostic power of amyloid-β PET using a data-driven spatially informed classifier for decision support","year":2021,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Engineering and Physical Sciences Research Council; National Institute for Health and Care Research; Canadian Institutes of Health Research; Alzheimer Society; Medical Research Council; Alzheimer's Society","keywords":"Voxel; Artificial intelligence; Neuroimaging; Classifier (UML); Positron emission tomography; Pattern recognition (psychology); Medicine; Support vector machine; Pet imaging; Alzheimer's disease; Machine learning; Computer science; Nuclear medicine; Pathology; Disease","score_opus":0.23921083524391842,"score_gpt":0.46828031487087807,"score_spread":0.22906947962695964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3212409089","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830115,0.004040885,0.0043191486,0.002630586,0.00019094432,0.003284182,0.00015560833,0.00003123591,0.0023359377],"genre_scores_gemma":[0.990463,0.0019165241,0.0060548256,0.0005623806,0.00018461005,0.00016910354,0.00031348705,0.000055024215,0.000281036],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99585265,0.00036256315,0.0005438145,0.00052928174,0.0018416789,0.0008700099],"domain_scores_gemma":[0.989044,0.0074023977,0.000114705246,0.0012502725,0.0019357037,0.0002528862],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002851944,0.00019762019,0.00037950237,0.00025593262,0.00038440633,0.00013258436,0.0006479716,0.000068293324,0.0018264392],"category_scores_gemma":[0.0060317675,0.0001320737,0.00016231267,0.00072912965,0.00041378374,0.00029981576,0.0005847029,0.00049707864,0.00004422666],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0075101294,0.0026425312,0.13320999,0.00021696679,0.00653239,0.0009633812,0.0036202506,0.000043770662,0.1912367,0.00045359175,0.039061204,0.6145091],"study_design_scores_gemma":[0.026675325,0.010304303,0.383048,0.002099331,0.0015315053,0.00087465876,0.008003178,0.024122978,0.21194856,0.0017120232,0.3283956,0.0012845293],"about_ca_topic_score_codex":0.00012356196,"about_ca_topic_score_gemma":0.00009232856,"teacher_disagreement_score":0.61322457,"about_ca_system_score_codex":0.0000561078,"about_ca_system_score_gemma":0.0022185834,"threshold_uncertainty_score":0.999086},"labels":[],"label_agreement":null},{"id":"W32234072","doi":"10.1186/s13195-020-00595-5","title":"Strengthening Resilience by thinking of Knowledge as a Nutrient that connects the personal to global thinking","year":2014,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Coastal and Marine Management","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Commonwealth Scientific and Industrial Research Organisation; Government of Canada; York University; BrightFocus Foundation","keywords":"Resilience (materials science); Systems thinking; Knowledge management; Sociology; Epistemology; Psychology; Computer science; Philosophy; Artificial intelligence","score_opus":0.04958194786638702,"score_gpt":0.33522461837405204,"score_spread":0.285642670507665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W32234072","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7986839,0.0037049328,0.002329333,0.009124527,0.00024165685,0.0017561541,0.00001224819,0.00009465657,0.18405263],"genre_scores_gemma":[0.99814004,0.00019238109,0.00028915398,0.00065988634,0.00006167305,0.000055396442,0.0000031708812,0.000015377222,0.00058294064],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99660933,0.0004593162,0.00020900802,0.0004961912,0.0015645387,0.0006615922],"domain_scores_gemma":[0.998793,0.0004531505,0.0000670172,0.00046274276,0.00004418023,0.00017992097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002895345,0.00018461999,0.00017763839,0.000050418075,0.0006230754,0.00012657966,0.0012023101,0.000044895973,0.00084364566],"category_scores_gemma":[0.00011827348,0.00012344225,0.00008410842,0.00070282136,0.00041693068,0.00016179615,0.0030437636,0.0002819822,0.00033797658],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036549545,0.00042676646,0.010662365,0.000010046597,0.00025109225,0.0000061851238,0.019790094,0.0001645864,0.005674639,0.023333542,0.048738156,0.890577],"study_design_scores_gemma":[0.0017580289,0.0020685908,0.015550902,0.0001451911,0.000053994052,0.000013705011,0.0059988513,0.0029744462,0.029351229,0.10101583,0.84034926,0.00071995886],"about_ca_topic_score_codex":0.002933887,"about_ca_topic_score_gemma":0.00042977463,"teacher_disagreement_score":0.88985705,"about_ca_system_score_codex":0.000102561935,"about_ca_system_score_gemma":0.000029540313,"threshold_uncertainty_score":0.9237328},"labels":[],"label_agreement":null},{"id":"W4205791976","doi":"10.1186/s13195-022-00960-6","title":"Correction to: BMI1 is associated with CSF amyloid-β and rates of cognitive decline in Alzheimer’s disease","year":2022,"lang":"en","type":"erratum","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; U.S. National Library of Medicine; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; National Institute on Aging; Alzheimer's Association","keywords":"Cognitive decline; Disease; Amyloid (mycology); Amyloid β; Psychology; Medicine; Psychiatry; Gerontology; Neuroscience; Dementia; Pathology","score_opus":0.08754149471738572,"score_gpt":0.41601839418404213,"score_spread":0.3284768994666564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205791976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60311043,0.28306487,0.0000399456,0.019887855,0.008940919,0.026279354,0.0020149827,0.00027465436,0.056386963],"genre_scores_gemma":[0.9126346,0.025404867,0.000024516243,0.0029166234,0.00056116807,0.0022559224,0.0034557541,0.0002791709,0.052467376],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9921473,0.0014478524,0.0006469768,0.0011704502,0.0033538598,0.0012335316],"domain_scores_gemma":[0.9944798,0.0018317219,0.00022375521,0.0005378837,0.0021109146,0.000815926],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0029305774,0.0005546801,0.0010447613,0.0017179727,0.00033415479,0.0001269721,0.00039316778,0.0002588863,0.0043297056],"category_scores_gemma":[0.00151508,0.0004628531,0.00019008266,0.0024479404,0.0006659595,0.00018884736,0.0005170306,0.0030798689,0.000045896955],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019219158,0.0032161141,0.16209702,0.000068511894,0.008369491,0.0006727113,0.0018709895,9.897678e-7,0.0002217032,0.0000072625835,0.7192031,0.08505296],"study_design_scores_gemma":[0.01124515,0.013214226,0.8220357,0.0032605007,0.0015567298,0.00002778384,0.0022149147,0.00037152966,0.0031978663,0.00019443323,0.14179239,0.0008888155],"about_ca_topic_score_codex":0.0016116678,"about_ca_topic_score_gemma":0.0005353976,"teacher_disagreement_score":0.65993863,"about_ca_system_score_codex":0.00016773841,"about_ca_system_score_gemma":0.0022297753,"threshold_uncertainty_score":0.9997823},"labels":[],"label_agreement":null},{"id":"W4206343614","doi":"10.1186/s13195-021-00949-7","title":"Mild behavioral impairment: measurement and clinical correlates of a novel marker of preclinical Alzheimer’s disease","year":2022,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Dementia; Biomarker; Disease; Geriatric psychiatry; Neurology; Medicine; Neurodegeneration; Cognitive impairment; Alzheimer's disease; Neuroimaging; Psychiatry; Internal medicine","score_opus":0.552941926156312,"score_gpt":0.5486916578335572,"score_spread":0.004250268322754769,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206343614","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0033441295,0.98818064,0.0000059259437,0.00016182761,0.00023966063,0.007340641,0.00025331654,0.000034376626,0.00043945678],"genre_scores_gemma":[0.007944422,0.9899267,0.00018047294,0.000048245416,0.00018608088,0.0011430552,0.00025704456,0.00015942051,0.00015453881],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98695767,0.0030005716,0.0025891154,0.0013213232,0.00497406,0.0011572411],"domain_scores_gemma":[0.99346095,0.002120575,0.00067317346,0.001344168,0.0012500563,0.0011510451],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.013163809,0.00069514255,0.0031077836,0.00092268205,0.00023870094,0.000052164552,0.0007948032,0.00042652595,0.0033275317],"category_scores_gemma":[0.00059298443,0.0005313816,0.0017322797,0.0010916645,0.0017133649,0.00012830703,0.0009358559,0.0027313924,0.00002746121],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003424305,0.011861155,0.026099749,0.0019815795,0.010711475,0.00007433046,0.00008600067,3.747741e-8,0.0000050249705,0.000031398384,0.0014563769,0.9442686],"study_design_scores_gemma":[0.008220404,0.011891689,0.035504207,0.007155562,0.013482491,0.00004540981,0.00015585659,0.000035314453,0.000022051128,0.000043644406,0.92281157,0.00063178997],"about_ca_topic_score_codex":0.00016536565,"about_ca_topic_score_gemma":0.0000069753833,"teacher_disagreement_score":0.9436368,"about_ca_system_score_codex":0.00012734247,"about_ca_system_score_gemma":0.0033317618,"threshold_uncertainty_score":0.9997138},"labels":[],"label_agreement":null},{"id":"W4206983508","doi":"10.1186/s13195-021-00941-1","title":"Model-based stratification of progression along the Alzheimer disease continuum highlights the centrality of biomarker synergies","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Pfizer; Novartis Pharmaceuticals Corporation; Eisai; Meso Scale Diagnostics; Northern California Institute for Research and Education; F. Hoffmann-La Roche; University of Southern California; Bristol-Myers Squibb; Eli Lilly and Company; Biogen; Foundation for the National Institutes of Health","keywords":"Geriatric psychiatry; Neurology; Centrality; Biomarker; Disease; Medicine; Risk stratification; Neuroscience; Bioinformatics; Internal medicine; Psychology; Psychiatry; Biology; Mathematics","score_opus":0.13272155703277777,"score_gpt":0.41687484690110393,"score_spread":0.28415328986832616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206983508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94348437,0.028773447,0.00016328182,0.022119762,0.00008996033,0.004311266,0.00008491834,0.000038174665,0.00093482557],"genre_scores_gemma":[0.99785364,0.0005864465,0.00007583139,0.00018320532,0.000040673145,0.00092902506,0.0001117634,0.000030496873,0.00018893433],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99411327,0.0017951321,0.0004953181,0.0004014441,0.0026019306,0.00059292576],"domain_scores_gemma":[0.99715835,0.00059974025,0.00018410974,0.00096074806,0.00090108684,0.00019594475],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003836251,0.00018692321,0.0002771854,0.00021358064,0.0007154419,0.000049320595,0.0006415851,0.000042751115,0.00080514466],"category_scores_gemma":[0.00008942987,0.0000985625,0.00022259659,0.0008509561,0.001120236,0.00011168124,0.00020223559,0.0005127848,0.0000059323543],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03341417,0.011312082,0.2210367,0.00023767672,0.009087614,0.00009179624,0.0047108512,0.0004299383,0.30938578,0.010675007,0.034347836,0.36527056],"study_design_scores_gemma":[0.0046738377,0.0018908626,0.64220816,0.00014060237,0.00076681294,0.0000051811116,0.0018292987,0.018491223,0.31120202,0.0019009861,0.016590636,0.00030036166],"about_ca_topic_score_codex":0.00020964637,"about_ca_topic_score_gemma":0.000019387784,"teacher_disagreement_score":0.4211715,"about_ca_system_score_codex":0.000034403613,"about_ca_system_score_gemma":0.0008295219,"threshold_uncertainty_score":0.88157696},"labels":[],"label_agreement":null},{"id":"W4210357094","doi":"10.1186/s13195-021-00942-0","title":"The accuracy and robustness of plasma biomarker models for amyloid PET positivity","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute on Aging; Göteborgs Universitet; Canadian Institutes of Health Research; Hjärnfonden","keywords":"Geriatric psychiatry; Robustness (evolution); Neurology; Biomarker; Amyloid β; Amyloid (mycology); Medicine; Computational biology; Internal medicine; Pathology; Biology; Psychiatry; Disease; Biochemistry","score_opus":0.14506634778047767,"score_gpt":0.4147930169028624,"score_spread":0.26972666912238474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210357094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981711,0.008349833,0.0005815198,0.0049999417,0.00007634885,0.0028919368,0.0000671242,0.00002192542,0.0013003789],"genre_scores_gemma":[0.9953407,0.0024726926,0.00021739543,0.00008461753,0.00005704897,0.001229938,0.00003575383,0.00003421153,0.0005276553],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9967025,0.0007137824,0.0002416509,0.00035721992,0.0013114434,0.00067341677],"domain_scores_gemma":[0.99662477,0.0021681958,0.000059662503,0.00039828828,0.0005749725,0.00017409798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0039491733,0.00014000841,0.00023572527,0.00022530496,0.0010946479,0.00007559023,0.0003126827,0.000024484067,0.00024329207],"category_scores_gemma":[0.0001565349,0.000095922725,0.00012012246,0.0004913545,0.0004992854,0.00016020567,0.00033830557,0.00042645857,0.000002411039],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02308815,0.0019297764,0.0058540055,0.00008689181,0.004279056,0.000066824454,0.00086495717,0.00015849138,0.14984466,0.0027851907,0.012383494,0.7986585],"study_design_scores_gemma":[0.043339662,0.019946821,0.14252509,0.0001777342,0.0007444889,0.00082599977,0.010019601,0.29913443,0.24634649,0.01013952,0.22547995,0.0013202182],"about_ca_topic_score_codex":0.00010595254,"about_ca_topic_score_gemma":0.0000094770885,"teacher_disagreement_score":0.7973383,"about_ca_system_score_codex":0.00003877717,"about_ca_system_score_gemma":0.00028124833,"threshold_uncertainty_score":0.84192574},"labels":[],"label_agreement":null},{"id":"W4210720631","doi":"10.1186/s13195-022-00964-2","title":"Detection of plasma Aβ seeding activity by a newly developed analyzer for diagnosis of Alzheimer’s disease","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Key Scientific Instrument and Equipment Development Projects of China; National Natural Science Foundation of China","keywords":"Dementia; Seeding; Neurology; Biomarker; Medicine; Internal medicine; Receiver operating characteristic; Tau protein; Mini–Mental State Examination; Alzheimer's disease; Disease; Psychiatry; Chemistry; Biochemistry; Biology","score_opus":0.14267128097278323,"score_gpt":0.40683546437248075,"score_spread":0.2641641833996975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210720631","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9325994,0.061169308,0.000094767405,0.0012769973,0.000096821015,0.0037948487,0.0007276685,0.00005822621,0.00018196522],"genre_scores_gemma":[0.99314845,0.0027080106,0.0002478418,0.00005999569,0.00008657957,0.0034229592,0.00017926296,0.00009216639,0.000054756732],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99508077,0.00064384507,0.00050461415,0.00068890094,0.002123272,0.0009586246],"domain_scores_gemma":[0.99664116,0.00082368107,0.00022129789,0.00068166095,0.0008353265,0.0007968761],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001510993,0.00031751936,0.0006583338,0.0007115146,0.0006346739,0.000030672207,0.0003711608,0.00008800294,0.0005190711],"category_scores_gemma":[0.00023192803,0.00028474754,0.00043152014,0.0014022394,0.00041278818,0.00024639818,0.00025780182,0.0005569763,0.000012204791],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.058410868,0.012770965,0.13284643,0.00024271422,0.11070727,0.00018883817,0.0012968881,0.00007001411,0.09104298,0.0001366879,0.020060893,0.57222545],"study_design_scores_gemma":[0.01788719,0.007215168,0.069706865,0.00012812365,0.003731782,0.000018571189,0.00080858835,0.0030875471,0.8726172,0.0005712451,0.023508478,0.00071923836],"about_ca_topic_score_codex":0.00082685007,"about_ca_topic_score_gemma":0.000017169985,"teacher_disagreement_score":0.78157425,"about_ca_system_score_codex":0.00016137089,"about_ca_system_score_gemma":0.0010957654,"threshold_uncertainty_score":0.9999605},"labels":[],"label_agreement":null},{"id":"W4213061596","doi":"10.1186/s13195-022-00961-5","title":"Altered central and blood glutathione in Alzheimer’s disease and mild cognitive impairment: a meta-analysis","year":2022,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Sunnybrook Hospital; Health Sciences Centre; Toronto Rehabilitation Institute; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Alzheimer Society Research Program; Alzheimer Society; Alzheimer's Association","keywords":"Glutathione; Oxidative stress; Neurodegeneration; Medicine; Neurology; Disease; Alzheimer's disease; Antioxidant; Cognitive impairment; Internal medicine; Neuroscience; Psychology; Psychiatry; Chemistry; Biochemistry; Enzyme","score_opus":0.2982491192128955,"score_gpt":0.4410175449006796,"score_spread":0.14276842568778414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213061596","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002083808,0.99483836,0.000004046282,0.00012483446,0.00007150563,0.0022604945,0.00053380954,0.00001385397,0.0000693184],"genre_scores_gemma":[0.008673777,0.9874076,0.00007388538,0.0001876019,0.00019700581,0.0017211573,0.0015999634,0.00009333945,0.000045629513],"study_design_codex":"meta_analysis","study_design_gemma":"not_applicable","domain_scores_codex":[0.9926866,0.0033864144,0.0006913535,0.0016064896,0.0005673308,0.0010617556],"domain_scores_gemma":[0.9977284,0.0006126327,0.00022172047,0.0008469195,0.000121292156,0.00046904112],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017116872,0.0006701561,0.0022055826,0.0007946726,0.00028050967,0.000106660875,0.00061567593,0.00036152097,0.00049204275],"category_scores_gemma":[0.0001165944,0.0005365519,0.0012414596,0.0010746807,0.00065150345,0.000009935688,0.00087007124,0.00093143655,0.0000051604925],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011426134,0.000831578,0.00017201497,0.00023868593,0.7208122,0.00018098354,0.00026003263,0.0000020202533,0.000060837818,0.000041877127,0.00038654322,0.27587062],"study_design_scores_gemma":[0.0018746974,0.0011980069,0.00033272913,0.00007962166,0.28319535,0.00006554401,0.00009402357,0.000010066938,0.000109856825,0.0001599868,0.7119567,0.0009234524],"about_ca_topic_score_codex":0.00018701346,"about_ca_topic_score_gemma":0.00008815996,"teacher_disagreement_score":0.71157014,"about_ca_system_score_codex":0.000023562892,"about_ca_system_score_gemma":0.00046360533,"threshold_uncertainty_score":0.9997086},"labels":[],"label_agreement":null},{"id":"W4213329441","doi":"10.1186/s13195-022-00973-1","title":"Relationship of sex differences in cortical thickness and memory among cognitively healthy subjects and individuals with mild cognitive impairment and Alzheimer disease","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute on Aging; Canadian Institutes of Health Research","keywords":"Cognitive impairment; Disease; Psychology; Cognition; Memory impairment; Audiology; Medicine; Neuroscience; Internal medicine","score_opus":0.10776392208053873,"score_gpt":0.3833260487735313,"score_spread":0.2755621266929926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213329441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97236127,0.022418529,0.0000068513887,0.0016702965,0.000014356121,0.0031142393,0.00008546443,0.000019345202,0.00030968033],"genre_scores_gemma":[0.99682033,0.001694914,0.000046174966,0.0003533679,0.000031404517,0.0008948193,0.000056199788,0.000035415185,0.00006738767],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99477315,0.0018829016,0.00037361405,0.0006611134,0.0016014787,0.00070775],"domain_scores_gemma":[0.9965751,0.0021633597,0.000090344656,0.00018516474,0.00036770263,0.00061832764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028523076,0.00024961607,0.00046842053,0.0006519585,0.0005862068,0.00006993465,0.00011471513,0.00006826586,0.00023865487],"category_scores_gemma":[0.00015153128,0.00019653446,0.000039027193,0.00071423844,0.0017166601,0.00020071915,0.00031415527,0.001118425,0.0000018006953],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006778557,0.00094347075,0.9740986,0.000059150854,0.00072647294,0.000111112226,0.004172884,1.1629401e-7,0.0000642863,0.0000739744,0.00004147653,0.0129299],"study_design_scores_gemma":[0.00811129,0.0052812975,0.9736168,0.00016245882,0.00028788374,0.000037237223,0.011283809,0.00007923556,0.00054390135,0.00036475077,0.000028657652,0.00020268663],"about_ca_topic_score_codex":0.00038434364,"about_ca_topic_score_gemma":0.000040503422,"teacher_disagreement_score":0.024459079,"about_ca_system_score_codex":0.000029975214,"about_ca_system_score_gemma":0.0005082054,"threshold_uncertainty_score":0.8014443},"labels":[],"label_agreement":null},{"id":"W4220762197","doi":"10.1186/s13195-022-00962-4","title":"Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Biomedical Imaging and Bioengineering; National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases; National Human Genome Research Institute; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Institute on Aging; Center for Innovative Medicine; Fundação para a Ciência e a Tecnologia; National Health and Medical Research Council; Economic and Social Research Council; Medical Research Council; Genentech; National Institutes of Health; Fondation pour la Recherche sur Alzheimer; Amsterdam Neuroscience; Seinäjoen Keskussairaala; Sorbonne Université; Associazione Italiana Ricerca Alzheimer; UK Dementia Research Institute; Ludwig Boltzmann Gesellschaft; Demensfonden; IXICO; Stichting ALS Nederland; Nederlandse Federatie van Universitair Medische Centra; Alzheimer Nederland; Università degli Studi di Camerino; Instituto de Investigación Marqués de Valdecilla; Stichting Dioraphte; Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta; Mutuelle Générale de l'Education Nationale; Universität zu Köln; Agence Française de Sécurité Sanitaire des Produits de Santé; Fundación Salud 2000; Aristotle University of Thessaloniki; Sahlgrenska Universitetssjukhuset; Deutsches Zentrum für Neurodegenerative Erkrankungen; South London and Maudsley NHS Foundation Trust; Rigshospitalet; Novo Nordisk; Vetenskapsrådet; Banco Bilbao Vizcaya Argentaria; Canadian Institutes of Health Research; European Commission; Knut och Alice Wallenbergs Stiftelse; Amsterdam University Medical Centers; Université de Lille; Karolinska Institutet; Juho Vainion Säätiö; Health~Holland; Ministerstvo Zdravotnictví Ceské Republiky; Fonds Wetenschappelijk Onderzoek; Suomen Kulttuurirahasto; University College London Hospitals NHS Foundation Trust; Ministerio de Economía y Competitividad; Erasmus Medisch Centrum; Univerzita Karlova v Praze; Generalitat de Catalunya; Bundesministerium für Bildung und Forschung; Universitetet i Oslo; University of Nottingham; Lundbeckfonden; AXA Research Fund; Vrije Universiteit Amsterdam; Stockholms Läns Landsting; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Ministero della Salute; H. Lundbeck A/S; European Federation of Pharmaceutical Industries and Associations; Institut National de la Santé et de la Recherche Médicale; National Institute on Minority Health and Health Disparities; Universität Heidelberg; North Bristol NHS Trust; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; King's College London; Gentofte Hospital; Deutsche Forschungsgemeinschaft; National Research Foundation; Cardiff University; University of Bristol; Socialdepartementet; BioClinica; Newcastle University; University of Oxford; Universitat de Barcelona; Grifols; Servier; Academy of Finland; Higher Education Funding Council for Wales; National Institute for Health and Care Research; Dipartimenti di Eccellenza; Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease; Ministero dell’Istruzione, dell’Università e della Ricerca; Fundación BBVA; Alzheimer's Association; Meso Scale Diagnostics; Yrjö Jahnssonin Säätiö; Northern California Institute for Research and Education; Translational Genomics Research Institute; Sigrid Juséliuksen Säätiö; Stichting MS Research; University of Southampton; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; Alzheimer's Society; Universiteit Antwerpen; Ministerstvo Školství, Mládeže a Tělovýchovy; National Institute for Social Care and Health Research; Motor Neurone Disease Association; Novartis Pharmaceuticals Corporation; ZonMw; University of Cambridge; University of Pittsburgh; University of Miami; EU Joint Programme – Neurodegenerative Disease Research; University of Washington; Pfizer; Wellcome Trust; Agence Nationale de la Recherche; Uniformed Services University of the Health Sciences; Biogen; University of Pennsylvania; Fondation de France; Eisai; Sanofi; Vlaamse regering; Broad Institute; Universidade de Aveiro; University of Southern California; Foundation for the National Institutes of Health; Uppsala Universitet; Rush University; F. Hoffmann-La Roche; Vanderbilt University; Instituto de Salud Carlos III; Universidad de Cantabria; National Cancer Institute; European Regional Development Fund; Alzheimer's Research Trust; Hersenstichting; U.S. Department of Defense; Eli Lilly and Company; Itä-Suomen Yliopisto; Illinois Department of Public Health; GlaxoSmithKline; Bristol-Myers Squibb; Alzheimer's Disease Neuroimaging Initiative; Fondation pour la Recherche Médicale","keywords":"Genotyping; Apolipoprotein E; Locus (genetics); Medicine; Genetics; Computational biology; Data science; Biology; Computer science; Genotype; Internal medicine; Gene; Disease","score_opus":0.3684760738879566,"score_gpt":0.4489423383417875,"score_spread":0.08046626445383087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220762197","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.044801388,0.8991624,0.0010253291,0.02808269,0.00021504414,0.015812984,0.00061304925,0.00026173692,0.010025385],"genre_scores_gemma":[0.97914666,0.01044273,0.0003470821,0.00085741654,0.00040761614,0.007796261,0.00036485348,0.00013103469,0.0005063324],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99202764,0.0023298042,0.00049849396,0.0010342886,0.0024400854,0.001669699],"domain_scores_gemma":[0.99534506,0.0017724427,0.00014059662,0.0014588743,0.00064626406,0.0006367422],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0057418696,0.00039270194,0.0006287315,0.00029092358,0.0025091677,0.00010999339,0.00078223716,0.00011274582,0.0008602532],"category_scores_gemma":[0.00022288914,0.0002611343,0.00045306154,0.0006356131,0.00057882495,0.00016736776,0.00046458852,0.0010541813,0.00010499996],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.101167694,0.014579568,0.0054463046,0.00050203095,0.22302365,0.0004712716,0.00974202,0.0020665543,0.004987134,0.008057555,0.07391282,0.5560434],"study_design_scores_gemma":[0.15958686,0.025773033,0.050989788,0.00022727068,0.006221267,0.00070435397,0.03616406,0.028787214,0.014665692,0.008762679,0.6636334,0.0044843643],"about_ca_topic_score_codex":0.00034835978,"about_ca_topic_score_gemma":0.000034456552,"teacher_disagreement_score":0.9343453,"about_ca_system_score_codex":0.0003596767,"about_ca_system_score_gemma":0.00074170774,"threshold_uncertainty_score":0.9999841},"labels":[],"label_agreement":null},{"id":"W4220890844","doi":"10.1186/s13195-022-00981-1","title":"Pilot study of repeated blood-brain barrier disruption in patients with mild Alzheimer’s disease with an implantable ultrasound device","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute on Aging; Bpifrance","keywords":"Medicine; Geriatric psychiatry; Neurology; Ultrasound; Disease; Neurosurgery; Neuroradiology; Blood–brain barrier; Internal medicine; Radiology; Psychiatry; Central nervous system","score_opus":0.06501746226846805,"score_gpt":0.3159845446459777,"score_spread":0.25096708237750964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220890844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99525315,0.0020710765,0.000006977118,0.000033374436,0.000025568093,0.0020380528,0.00014395664,0.00011246939,0.00031538372],"genre_scores_gemma":[0.9982717,0.000087533415,0.000086500324,0.000052206182,0.000029273262,0.0010940464,0.00025693816,0.00009969075,0.000022133554],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99727756,0.00042857692,0.0003097334,0.0004618249,0.0009632416,0.0005590361],"domain_scores_gemma":[0.9984423,0.00031184783,0.000050034716,0.000764465,0.00017857453,0.00025277014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005978666,0.00024522076,0.0002699811,0.00031734968,0.0003977702,0.00006253134,0.00045794284,0.000022088117,0.0002121317],"category_scores_gemma":[0.000012013698,0.00019932723,0.000024838882,0.0011430567,0.000105843836,0.0002921707,0.00004542207,0.00053926895,0.0000063064535],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009719233,0.018110368,0.9130996,0.000027265998,0.0045229224,0.000031635427,0.008768417,0.017446045,0.021306233,0.00016729983,0.0011755184,0.005625503],"study_design_scores_gemma":[0.014739637,0.022900445,0.94839567,0.00004883453,0.00052158907,0.000013158518,0.004596389,0.000547909,0.0023667468,0.00016875128,0.004681417,0.0010194676],"about_ca_topic_score_codex":0.0013269585,"about_ca_topic_score_gemma":0.000994507,"teacher_disagreement_score":0.035296097,"about_ca_system_score_codex":0.000043850618,"about_ca_system_score_gemma":0.00010310452,"threshold_uncertainty_score":0.81283283},"labels":[],"label_agreement":null},{"id":"W4221036217","doi":"10.1186/s13195-022-00958-0","title":"Cognitive composites for genetic frontotemporal dementia: GENFI-Cog","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Toronto; Occupational Cancer Research Centre; Health Sciences Centre; McGill University Health Centre; Sunnybrook Health Science Centre; Université Laval","funders":"Medical Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Stichting Dioraphte; Wolfson Foundation; UK Dementia Research Institute; National Institute for Health and Care Research; Alzheimer Nederland; Brain Research UK; Alzheimer's Society; Agence Nationale de la Recherche","keywords":"Frontotemporal dementia; Medicine; Logistic regression; Cognition; Neuropsychology; C9orf72; Internal medicine; Clinical trial; Dementia; Oncology; Psychology; Clinical psychology; Psychiatry; Disease","score_opus":0.21501653985870478,"score_gpt":0.43025141493464075,"score_spread":0.21523487507593597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221036217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9074381,0.07528796,0.00067540054,0.0075638536,0.00021135836,0.006961342,0.00017385557,0.00013855043,0.0015495972],"genre_scores_gemma":[0.99091995,0.0012047697,0.002814018,0.0009600579,0.00038752911,0.0026171908,0.00021344365,0.000106353415,0.00077666563],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99474263,0.00083475135,0.0003904133,0.00069935323,0.002102264,0.0012305791],"domain_scores_gemma":[0.9976464,0.000612079,0.000067447945,0.000509462,0.00075363426,0.00041097615],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016977576,0.00024722592,0.00041816695,0.00037513685,0.0011766898,0.00009874859,0.00051078683,0.000089571695,0.004705809],"category_scores_gemma":[0.00008317266,0.00021392212,0.0002373775,0.0006510646,0.0003927173,0.00011583253,0.0004214381,0.0010000184,0.00013771404],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.025908878,0.0044009653,0.15915857,0.000106497864,0.021497227,0.0005570831,0.0046259826,0.00008758995,0.24912457,0.0005588274,0.1127046,0.4212692],"study_design_scores_gemma":[0.026629372,0.018716827,0.6114074,0.00011066641,0.0008384838,0.00017828179,0.0019679628,0.0049829953,0.018842995,0.002833183,0.312405,0.0010868335],"about_ca_topic_score_codex":0.00066468836,"about_ca_topic_score_gemma":0.000018383982,"teacher_disagreement_score":0.45224884,"about_ca_system_score_codex":0.00014624443,"about_ca_system_score_gemma":0.00045585653,"threshold_uncertainty_score":0.996204},"labels":[],"label_agreement":null},{"id":"W4223495646","doi":"10.1186/s13195-022-01000-z","title":"Reconfigured metabolism brain network in asymptomatic microtubule-associated protein tau mutation carriers: a graph theoretical analysis","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Beijing Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Default mode network; Precuneus; Neuroscience; Posterior cingulate; Connectome; Human Connectome Project; Medicine; Frontotemporal dementia; Insula; Psychology; Functional magnetic resonance imaging; Internal medicine; Dementia; Disease; Functional connectivity","score_opus":0.07319476160526225,"score_gpt":0.3441760864596612,"score_spread":0.27098132485439896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223495646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9532954,0.005391117,0.00017076066,0.035263814,0.00030907473,0.0036997125,0.00010654497,0.00021733412,0.0015462367],"genre_scores_gemma":[0.9944235,0.000083967585,0.00009511301,0.00263709,0.00009200631,0.0023927253,0.000031803916,0.00005331473,0.00019046206],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9877785,0.0076542827,0.00049883424,0.0010367843,0.0018129753,0.001218661],"domain_scores_gemma":[0.9897272,0.00916029,0.00015492301,0.0005897312,0.00021279429,0.00015506522],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00690557,0.0002889617,0.0005726278,0.0012079659,0.0015210797,0.00016001542,0.0007184187,0.00010027044,0.0014687225],"category_scores_gemma":[0.0068329438,0.00027940253,0.0003102588,0.008811331,0.00079008617,0.00028125063,0.00031433516,0.0011732446,0.000034477318],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008570215,0.0043219556,0.0039049357,0.000037445767,0.021430222,0.0008845997,0.026962942,0.023612617,0.5162329,0.27320215,0.059986915,0.06085309],"study_design_scores_gemma":[0.015880477,0.0042356313,0.06923068,0.0001178873,0.0011476101,0.00007691038,0.0065080384,0.03303225,0.16456328,0.6633353,0.03868105,0.003190875],"about_ca_topic_score_codex":0.00043811937,"about_ca_topic_score_gemma":0.00026739796,"teacher_disagreement_score":0.39013317,"about_ca_system_score_codex":0.00020812431,"about_ca_system_score_gemma":0.00024474034,"threshold_uncertainty_score":0.9999658},"labels":[],"label_agreement":null},{"id":"W4226029213","doi":"10.1186/s13195-022-00991-z","title":"Sex differences in neuropsychiatric symptoms in Alzheimer’s disease dementia: a meta-analysis","year":2022,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; St. Michael's Hospital; University of Calgary","funders":"ZonMw","keywords":"Meta-analysis; Dementia; Confidence interval; PsycINFO; Odds ratio; Medicine; Publication bias; MEDLINE; Alzheimer's disease; Psychosis; Clinical Dementia Rating; Internal medicine; Disease; Psychiatry; Biology","score_opus":0.36333312946105484,"score_gpt":0.4699378439240641,"score_spread":0.10660471446300929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226029213","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004136594,0.9906481,0.0000038755156,0.0006243143,0.00009778344,0.0065841917,0.000114346774,0.00005698763,0.0014567557],"genre_scores_gemma":[0.0095082605,0.98102015,0.000026707097,0.0002493161,0.00014063227,0.0077735535,0.0005444553,0.00016434352,0.000572592],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98236287,0.007511936,0.0016603394,0.0020834536,0.004323546,0.0020578345],"domain_scores_gemma":[0.99514145,0.0017283343,0.0003073832,0.0017047722,0.00024460262,0.00087348674],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0056204046,0.0010189908,0.0057219085,0.008286972,0.0003278552,0.00025148425,0.0014766215,0.00026718606,0.019646805],"category_scores_gemma":[0.00015971616,0.0007308281,0.004204259,0.012973637,0.00039271076,0.00020742962,0.0007333986,0.0035310283,0.0002155604],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036720376,0.0019371936,0.012845313,0.00043696418,0.4185989,0.0007858634,0.0001071547,6.1365193e-7,1.8978496e-7,0.000030272979,0.00043322975,0.5644571],"study_design_scores_gemma":[0.0014686553,0.0008771507,0.009946834,0.00015167499,0.3699133,0.000011860837,0.000091545866,0.000038875554,8.153664e-7,0.0000963198,0.6168143,0.0005886481],"about_ca_topic_score_codex":0.0007648893,"about_ca_topic_score_gemma":0.00013988132,"teacher_disagreement_score":0.6163811,"about_ca_system_score_codex":0.00017537264,"about_ca_system_score_gemma":0.0019758758,"threshold_uncertainty_score":0.9995143},"labels":[],"label_agreement":null},{"id":"W4229451673","doi":"10.1186/s13195-022-01007-6","title":"The course of primary progressive aphasia diagnosis: a cross-sectional study","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Primary progressive aphasia; Medical diagnosis; Aphasia; Cohort; Epidemiology; Medical prescription; Population ageing; Population; Disease; Pediatrics; Dementia; Internal medicine; Psychiatry; Pathology","score_opus":0.13305336139131235,"score_gpt":0.4661806278803119,"score_spread":0.33312726648899954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229451673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95555705,0.03641792,0.0000017674887,0.0012238796,0.00012545573,0.0042545972,0.000030186466,0.000033451477,0.0023556678],"genre_scores_gemma":[0.99097294,0.0011025197,0.00001373421,0.00017471418,0.0001520942,0.006728184,0.000035914392,0.000034880075,0.00078501937],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.993785,0.0013528641,0.00040094633,0.000449413,0.0032672938,0.0007444604],"domain_scores_gemma":[0.9971348,0.0008919186,0.00009659429,0.0005694789,0.0011142215,0.00019298395],"candidate_categories":["sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005389134,0.00016324586,0.00026450102,0.00023259736,0.0015410528,0.00013522596,0.0005593694,0.00003799739,0.0018372473],"category_scores_gemma":[0.00009743255,0.00010648806,0.00017147984,0.0009383439,0.0008048794,0.000109220426,0.00045994803,0.0010109921,0.000031543594],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033674024,0.005955056,0.9130252,0.000008687424,0.0024383974,0.00017916135,0.0008190177,0.0000013541473,0.00062934717,0.00004892517,0.0038477557,0.069679715],"study_design_scores_gemma":[0.004289023,0.008122814,0.95786184,0.000009306334,0.000053121395,0.0000659301,0.0029701414,0.000015879752,0.002320835,0.00022104556,0.023970027,0.00010003982],"about_ca_topic_score_codex":0.000110215355,"about_ca_topic_score_gemma":0.0000066991292,"teacher_disagreement_score":0.069579676,"about_ca_system_score_codex":0.00010765412,"about_ca_system_score_gemma":0.0008943002,"threshold_uncertainty_score":0.9997588},"labels":[],"label_agreement":null},{"id":"W4254983461","doi":"10.1186/alz193","title":"Pharmacological recommendations for the symptomatic treatment of dementia: the Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012","year":2013,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Pharmaceutical Practices and Patient Outcomes","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary; Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Dementia; Medicine; Memantine; Discontinuation; Rivastigmine; Vascular dementia; Psychiatry; Disease; Donepezil; Intensive care medicine; Cognitive decline; Geriatric psychiatry; Dementia with Lewy bodies; MEDLINE; Internal medicine","score_opus":0.603433746097031,"score_gpt":0.5168111734444049,"score_spread":0.08662257265262618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254983461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.53566295,0.043740075,0.000008565525,0.40840793,0.00017503255,0.0105950255,0.00010391954,0.000012833119,0.0012936578],"genre_scores_gemma":[0.9659021,0.030482277,0.00008875835,0.0010268671,0.000048821006,0.0023353894,0.00001288372,0.000011484698,0.00009143251],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99833536,0.00051286956,0.00028005755,0.00017677924,0.00032049505,0.00037443935],"domain_scores_gemma":[0.99090505,0.008225886,0.000102470316,0.00031061415,0.0002704356,0.00018555111],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00057341874,0.00014876446,0.00023575044,0.000072525436,0.00054948457,0.000048428472,0.0001624348,0.000048348265,0.0026625036],"category_scores_gemma":[0.00008783394,0.00005678204,0.00010972143,0.00015304436,0.0004905472,0.000049360042,0.000019136394,0.00012510295,0.00002169247],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015172533,0.004929847,0.06937193,0.000030541778,0.037717033,0.000007401694,0.006536727,0.000008480399,0.0027537728,0.008858554,0.06073669,0.8075318],"study_design_scores_gemma":[0.013783152,0.020697074,0.086399935,0.000104256906,0.00728404,0.000016036909,0.0045240596,0.0106642,0.042272486,0.0020997925,0.81179327,0.00036170217],"about_ca_topic_score_codex":0.02173544,"about_ca_topic_score_gemma":0.004744337,"teacher_disagreement_score":0.8071701,"about_ca_system_score_codex":0.00006381146,"about_ca_system_score_gemma":0.00021280479,"threshold_uncertainty_score":0.9982492},"labels":[],"label_agreement":null},{"id":"W4280602597","doi":"10.1186/s13195-022-01013-8","title":"Explaining the association between social and lifestyle factors and cognitive functions: a pathway analysis in the Memento cohort","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Medical Research Council; Agence Nationale de la Recherche","keywords":"Dementia; Cognition; Structural equation modeling; Cohort; Neurology; Gerontology; Medicine; Cognitive decline; Cohort study; Psychology; Social cognition; Disease; Clinical psychology; Internal medicine; Psychiatry","score_opus":0.11093248213241466,"score_gpt":0.3998112803906887,"score_spread":0.288878798258274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280602597","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98916215,0.0034162917,0.000021171481,0.0044105235,0.000018286884,0.0015474135,0.000052093983,0.000014488471,0.0013575617],"genre_scores_gemma":[0.99769485,0.00034916934,0.0000024665685,0.00043023538,0.00012116924,0.00089618715,0.00016184375,0.000014962846,0.0003291157],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99474424,0.0023319547,0.00022394153,0.00035028317,0.001827686,0.000521897],"domain_scores_gemma":[0.99712026,0.0023077843,0.00007009218,0.00015038752,0.00026469212,0.000086780245],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0076568876,0.00013611105,0.00026712922,0.00047962434,0.0015392248,0.00016353703,0.00016258446,0.000049579798,0.0004455048],"category_scores_gemma":[0.00023502696,0.000081057246,0.00010112461,0.0017985553,0.00019650905,0.00011464492,0.00019142927,0.00090392126,0.000005213913],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019409253,0.00015734525,0.9674724,0.0000024584092,0.0056349505,0.000009006966,0.008894966,1.542746e-7,0.00009140887,0.00004226463,0.00045263753,0.01704835],"study_design_scores_gemma":[0.0013997059,0.0006588304,0.95223254,0.0000049301775,0.0008596921,0.0000018405478,0.038119484,0.000026463265,0.00017367413,0.00007913124,0.00636233,0.00008138886],"about_ca_topic_score_codex":0.00070757663,"about_ca_topic_score_gemma":0.00012692108,"teacher_disagreement_score":0.029224517,"about_ca_system_score_codex":0.00009742641,"about_ca_system_score_gemma":0.00014174262,"threshold_uncertainty_score":0.9997606},"labels":[],"label_agreement":null},{"id":"W4281672016","doi":"10.1186/s13195-022-01021-8","title":"Quantification of SNAP-25 with mass spectrometry and Simoa: a method comparison in Alzheimer’s disease","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Montreal Neurological Institute and Hospital; Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean; McGill University; Douglas Mental Health University Institute","funders":"National Institute on Aging; Canadian Institutes of Health Research; Göteborgs Universitet","keywords":"Snap; Medicine; Cerebrospinal fluid; Neurology; Pathology; Internal medicine; Pathophysiology; Cohort; Biomarker; Chemistry; Psychiatry; Biochemistry","score_opus":0.15631775384138924,"score_gpt":0.446792973498317,"score_spread":0.29047521965692774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281672016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60122865,0.38705352,0.0005997703,0.004385702,0.00006513552,0.005055342,0.00020039272,0.00009456519,0.0013168792],"genre_scores_gemma":[0.9931023,0.0021187884,0.003656125,0.000086225584,0.000049236347,0.0007004328,0.00018646075,0.000070531714,0.000029880013],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9943657,0.0013541938,0.00048447793,0.0007793446,0.0021415194,0.00087477354],"domain_scores_gemma":[0.9973282,0.0006117728,0.0001348674,0.0008625315,0.0003324905,0.0007301145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020751061,0.00029030818,0.00062563794,0.0010912475,0.00036610544,0.000049447965,0.0003283507,0.000060326387,0.00059974403],"category_scores_gemma":[0.000068827634,0.00023438466,0.00012071937,0.001947593,0.0004373835,0.000175173,0.00018000157,0.0009026827,0.00002139359],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.039449953,0.0108465925,0.7977007,0.00012199874,0.04586235,0.0014434225,0.0021518697,0.00023055961,0.012529044,0.0037559157,0.0031483085,0.0827593],"study_design_scores_gemma":[0.026408505,0.013952662,0.8877808,0.00024052296,0.0030440553,0.00010779671,0.006604859,0.008943354,0.03707827,0.004717038,0.009941519,0.0011806373],"about_ca_topic_score_codex":0.00066890585,"about_ca_topic_score_gemma":0.000023551931,"teacher_disagreement_score":0.39187363,"about_ca_system_score_codex":0.00011952988,"about_ca_system_score_gemma":0.00078197947,"threshold_uncertainty_score":0.9557929},"labels":[],"label_agreement":null},{"id":"W4282939192","doi":"10.1186/s13195-022-01012-9","title":"Correction: Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)—study protocol for a randomized controlled trial","year":2022,"lang":"en","type":"erratum","venue":"Alzheimer s Research & Therapy","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"","keywords":"Randomized controlled trial; Cognition; Protocol (science); Spermidine; Cognitive decline; Medicine; Gerontology; Psychology; Alternative medicine; Neuroscience; Biology; Dementia; Internal medicine; Pathology","score_opus":0.028166032528462576,"score_gpt":0.3923616040060956,"score_spread":0.36419557147763304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282939192","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.038302183,0.0017224939,0.0001467376,0.000116434036,0.0012733736,0.9573275,0.00018062243,0.000012525147,0.00091811555],"genre_scores_gemma":[0.085299335,0.0006526714,0.000027872964,0.00005627971,0.0006236119,0.9096181,0.0021569757,0.00006374904,0.0015014282],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9958438,0.0018944024,0.0005980144,0.00072986045,0.0005873491,0.00034656675],"domain_scores_gemma":[0.9970621,0.0015504542,0.00038845788,0.00027514738,0.00064880995,0.00007507177],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021908854,0.00034939218,0.0010650904,0.00040184968,0.00020017543,0.000038390324,0.00017192701,0.00019623195,0.00008152652],"category_scores_gemma":[0.0007444508,0.00025739986,0.00019708788,0.00042552693,0.00027787196,0.000008808156,0.00009145478,0.0004467571,6.6025547e-7],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.97397715,0.0026423933,0.00003450922,0.000060329305,0.0033116713,0.0000036966921,0.000486044,4.2676334e-7,0.0012353297,0.0000044471226,0.012980084,0.0052639386],"study_design_scores_gemma":[0.9628766,0.011389864,0.0004771453,0.00020842397,0.000437978,0.0000020111102,0.0008062784,0.00006637211,0.017822461,0.000029227029,0.0056194793,0.00026416613],"about_ca_topic_score_codex":0.00024612414,"about_ca_topic_score_gemma":0.00029377366,"teacher_disagreement_score":0.04770944,"about_ca_system_score_codex":0.000017521255,"about_ca_system_score_gemma":0.0004068656,"threshold_uncertainty_score":0.99998784},"labels":[],"label_agreement":null},{"id":"W4285042905","doi":"10.1186/s13195-022-01036-1","title":"Multidomain trials to prevent dementia: addressing methodological challenges","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Lawson Health Research Institute; Baycrest Hospital; Université de Montréal; Parkwood Institute; Western University","funders":"Consortium canadien en neurodégénérescence associée au vieillissement","keywords":"Geriatric psychiatry; Dementia; Neurology; Medicine; Psychiatry; Psychology; Intensive care medicine; Internal medicine; Disease","score_opus":0.7240447323608613,"score_gpt":0.5707670192632545,"score_spread":0.15327771309760685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285042905","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6915999,0.21942495,0.0012279538,0.058917534,0.0004859833,0.012869863,0.000057840007,0.00026556684,0.015150375],"genre_scores_gemma":[0.9798364,0.008065165,0.0052101295,0.0014889301,0.00042712988,0.0038623114,0.000042504646,0.00007049663,0.0009969277],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9806473,0.01367477,0.0006269279,0.0008207854,0.0029977635,0.0012324423],"domain_scores_gemma":[0.99525386,0.0029867708,0.000094795534,0.0006250655,0.00045357732,0.0005859002],"candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.038941987,0.0002538307,0.0007784967,0.00070067594,0.00090663787,0.000093418435,0.00052648375,0.000084367275,0.0097346315],"category_scores_gemma":[0.0016866793,0.00019422447,0.00033047498,0.0008371355,0.00019678802,0.000099534496,0.0008016205,0.0011708089,0.00018308028],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005111519,0.0033045057,0.0018738908,0.000028557664,0.004559903,0.0002611449,0.001842645,0.000008640394,0.099539116,0.00059474475,0.013254358,0.869621],"study_design_scores_gemma":[0.012005931,0.017616678,0.06158726,0.0001339648,0.0006033774,0.00014844585,0.008942113,0.00013708112,0.18502125,0.004002789,0.70905864,0.00074247265],"about_ca_topic_score_codex":0.00007327072,"about_ca_topic_score_gemma":0.000005718443,"teacher_disagreement_score":0.8688785,"about_ca_system_score_codex":0.00012441371,"about_ca_system_score_gemma":0.00034887347,"threshold_uncertainty_score":0.9911706},"labels":[],"label_agreement":null},{"id":"W4286716307","doi":"10.1186/s13195-022-01031-6","title":"Grey matter changes on brain MRI in subjective cognitive decline: a systematic review","year":2022,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Grey matter; Voxel-based morphometry; Entorhinal cortex; Neuropsychology; Meta-analysis; Magnetic resonance imaging; Psychology; Cognition; Voxel; Neuroimaging; Population; Sample size determination; Medicine; Hippocampus; Pathology; Neuroscience; Statistics; Radiology; Mathematics; White matter","score_opus":0.19673578074628797,"score_gpt":0.4835486111053649,"score_spread":0.2868128303590769,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286716307","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000021501344,0.9606144,0.0000019977974,0.0055139014,0.00009705169,0.027478214,0.000100213365,0.000051151226,0.0061215605],"genre_scores_gemma":[0.000043662476,0.96579826,0.0000078169405,0.008774222,0.00019560862,0.021795204,0.0005890863,0.00022778963,0.0025683371],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9832154,0.008820466,0.0012294735,0.0014349181,0.0036801407,0.0016196127],"domain_scores_gemma":[0.9890636,0.008246538,0.00037464895,0.0011260192,0.0007462968,0.00044289383],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.010348862,0.0008793629,0.00442698,0.0022035742,0.00030518143,0.00014663153,0.00090323156,0.00030529383,0.010127449],"category_scores_gemma":[0.0018414787,0.0006216488,0.000865268,0.0031997743,0.00035024446,0.000097128715,0.00059789704,0.003611298,0.0026903686],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000453706,0.0012631047,0.0002969561,0.51499075,0.005602021,0.0006560023,0.00027314876,5.0027027e-9,7.0632655e-7,0.000021477434,0.008131255,0.4683109],"study_design_scores_gemma":[0.0014507234,0.0024288925,0.00025698982,0.4397738,0.0018863602,0.000121599995,0.00021891874,6.3760876e-7,0.0000074186296,0.00003445904,0.5533784,0.00044179603],"about_ca_topic_score_codex":0.00015933043,"about_ca_topic_score_gemma":0.00007945445,"teacher_disagreement_score":0.54524714,"about_ca_system_score_codex":0.00045880603,"about_ca_system_score_gemma":0.0012827779,"threshold_uncertainty_score":0.9996235},"labels":[],"label_agreement":null},{"id":"W4293771139","doi":"10.1186/s13195-022-01042-3","title":"Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Western University; Montreal Neurological Institute and Hospital; University of Toronto; Occupational Cancer Research Centre; Health Sciences Centre; Sunnybrook Health Science Centre; Université Laval","funders":"NIHR Cambridge Biomedical Research Centre; Sahlgrenska Akademin; Medical Research Council; Olav Thon Stiftelsen; UK Dementia Research Institute; Stichting Dioraphte; Universität Ulm; Universität Duisburg-Essen; Göteborgs Universitet; Deutsches Zentrum für Neurodegenerative Erkrankungen; Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta; Università degli Studi di Milano; EU Joint Programme – Neurodegenerative Disease Research; Università degli Studi di Firenze; Vetenskapsrådet; Cambridge University Hospitals; Stockholms Läns Landsting; KU Leuven; Universidade de Coimbra; Imperial College London; University of Toronto; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Bundesministerium für Bildung und Forschung; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico; Alzheimer Nederland; Eberhard Karls Universität Tübingen; Hjärnfonden; Sahlgrenska Universitetssjukhuset; University of Oxford; ZonMw; University of Cambridge; National Institute for Health and Care Research; Familjen Erling-Perssons Stiftelse; Sunnybrook Research Institute; European Commission; Université de Lille; Weston Brain Institute; Alzheimer's Drug Discovery Foundation; Brain Research UK; Ministero della Salute; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Canadian Institutes of Health Research; Alzheimer's Society; Wellcome Trust; Sorbonne Université; Alzheimer's Association; Stiftelsen för Gamla Tjänarinnor; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; Centre National de la Recherche Scientifique; Wolfson Foundation; McGill University","keywords":"Frontotemporal dementia; Cerebrospinal fluid; Neurology; Dementia; Neuroscience; Medicine; Differential diagnosis; Pathology; Psychiatry; Psychology; Disease","score_opus":0.0936016053455491,"score_gpt":0.3677850938425485,"score_spread":0.27418348849699936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293771139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851157,0.010750787,0.000025379162,0.0017577299,0.0000606279,0.0020296257,0.000021533164,0.000011192695,0.0002274137],"genre_scores_gemma":[0.99827266,0.00088218396,0.00019424787,0.00008201434,0.000053070835,0.00042939876,0.0000308602,0.00003570262,0.000019886462],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99442405,0.0011064194,0.0006216086,0.00038339305,0.002671738,0.0007927915],"domain_scores_gemma":[0.9985937,0.00018540736,0.0001128198,0.00075479003,0.00020850757,0.00014479658],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0019464582,0.00018797442,0.0004205919,0.00044906695,0.00023435664,0.00002411754,0.0008141452,0.00006713648,0.0033677642],"category_scores_gemma":[0.00003099649,0.000119967255,0.000210706,0.00090977893,0.00050895347,0.00007444751,0.0003871478,0.0006840557,0.000009657795],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016812155,0.0060979296,0.32990626,0.00017719374,0.016232584,0.00021528275,0.00660185,0.000077004996,0.5580707,0.00055193214,0.005508381,0.05974868],"study_design_scores_gemma":[0.0059158783,0.009291122,0.97233933,0.0000587409,0.00013959073,0.000039011928,0.0013930678,0.0012020419,0.007640423,0.00062465266,0.0011678312,0.00018832083],"about_ca_topic_score_codex":0.0019257094,"about_ca_topic_score_gemma":0.000039903185,"teacher_disagreement_score":0.64243305,"about_ca_system_score_codex":0.00013458515,"about_ca_system_score_gemma":0.00034371729,"threshold_uncertainty_score":0.9975433},"labels":[],"label_agreement":null},{"id":"W4298139055","doi":"10.1186/s13195-022-01085-6","title":"Dramatic impacts on brain pathology, anxiety, and cognitive function in the knock-in APPNL-G-F mouse model of Alzheimer disease following long-term voluntary exercise","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick; University of Lethbridge","funders":"Alberta Prion Research Institute; Natural Sciences and Engineering Research Council of Canada; RIKEN; Alzheimer Society; Canadian Institutes of Health Research; Alberta Innovates","keywords":"Neurology; Anxiety; Disease; Neuroscience; Geriatric psychiatry; Medicine; Gene knockin; Cognition; Cognitive decline; Brain function; Psychiatry; Psychology; Internal medicine; Dementia; Biology","score_opus":0.07937024267072962,"score_gpt":0.37729618705744583,"score_spread":0.2979259443867162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298139055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89727145,0.096436314,0.000008716175,0.0020281598,0.00003804203,0.0038855837,0.00014081699,0.000030021229,0.0001608875],"genre_scores_gemma":[0.9937735,0.003236268,0.000023080322,0.0009346631,0.00004205009,0.001572309,0.00030447837,0.000078586076,0.00003505854],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99425566,0.0015402923,0.0004956783,0.0007531462,0.0018909393,0.001064291],"domain_scores_gemma":[0.9975855,0.00087863253,0.00009821938,0.00072843296,0.00015846887,0.0005507813],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0026312124,0.00037057957,0.0005784933,0.00092739816,0.0004255203,0.000058383906,0.00034600627,0.000098099226,0.00015743123],"category_scores_gemma":[0.00016726571,0.00027707967,0.0002621663,0.0010149913,0.00039928328,0.0002731041,0.00026665567,0.0011842869,0.000023961064],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.044474244,0.014187983,0.76222044,0.00018268282,0.020474374,0.0040120073,0.00997449,0.0003593372,0.0032282637,0.00015453796,0.002333174,0.13839845],"study_design_scores_gemma":[0.022665659,0.0053008595,0.95232785,0.00067391625,0.003078769,0.000059705544,0.0037270659,0.0066675926,0.002430705,0.0023206426,0.00003987488,0.0007073429],"about_ca_topic_score_codex":0.00037472785,"about_ca_topic_score_gemma":0.000050464023,"teacher_disagreement_score":0.19010742,"about_ca_system_score_codex":0.0000968625,"about_ca_system_score_gemma":0.0006334408,"threshold_uncertainty_score":0.9999681},"labels":[],"label_agreement":null},{"id":"W4308591117","doi":"10.1186/s13195-022-01109-1","title":"Driving assessment in preclinical Alzheimer’s disease: progress to date and the path forward","year":2022,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Older Adults Driving Studies","field":"Health Professions","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Disease; Neuroscience; Biomarker; Psychology; Cognition; Alzheimer's disease; Cognitive aging; Cognitive decline; Medicine; Dementia; Biology; Pathology","score_opus":0.47050570582764717,"score_gpt":0.6164190048092324,"score_spread":0.14591329898158523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308591117","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000064668464,0.97276485,0.000005425082,0.0078204265,0.0007244114,0.017544292,0.000094766394,0.000095570824,0.00088561815],"genre_scores_gemma":[0.0005487008,0.96809375,0.00026845356,0.0004239064,0.0006087573,0.029380519,0.00010312194,0.00023427096,0.0003385068],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.97291833,0.018979186,0.0019501077,0.0016526693,0.0022827794,0.0022169377],"domain_scores_gemma":[0.9791989,0.017216785,0.00051200966,0.0020723604,0.00030116283,0.0006988023],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.01759028,0.0008219178,0.002771554,0.0007105679,0.0028430272,0.00015133458,0.0020715399,0.00035266974,0.0011145414],"category_scores_gemma":[0.0012515291,0.00049666775,0.0005040873,0.0016391986,0.0010481862,0.00018515185,0.0039737127,0.0072761355,0.00022661433],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015037814,0.00025877907,0.006997621,0.0010697454,0.0026285336,0.00005178253,0.0030718176,3.7399542e-7,1.7432294e-8,0.0005461727,0.008694306,0.9765305],"study_design_scores_gemma":[0.0018773769,0.00023986839,0.0066793375,0.007521024,0.0007792392,0.0000018788697,0.00076250883,0.000025524305,2.8993844e-8,0.00031651155,0.98129094,0.0005057399],"about_ca_topic_score_codex":0.00035903728,"about_ca_topic_score_gemma":0.0004530337,"teacher_disagreement_score":0.97602475,"about_ca_system_score_codex":0.00025376244,"about_ca_system_score_gemma":0.0029142655,"threshold_uncertainty_score":0.9997986},"labels":[],"label_agreement":null},{"id":"W4310985942","doi":"10.1186/s13195-022-01110-8","title":"Gantenerumab: an anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer’s disease","year":2022,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Ontario Brain Institute; Sunnybrook Health Science Centre","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; National Institute of General Medical Sciences; Genentech; F. Hoffmann-La Roche","keywords":"Medicine; Drug development; Clinical trial; Disease; Context (archaeology); Population; Asymptomatic; Monoclonal antibody; Immunology; Drug; Pathology; Internal medicine; Pharmacology; Antibody; Biology","score_opus":0.16764474004021518,"score_gpt":0.4495101518988833,"score_spread":0.28186541185866815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310985942","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008124149,0.9793807,0.000010459776,0.00021190026,0.00023061283,0.011052214,0.00054802175,0.00025574522,0.00018616214],"genre_scores_gemma":[0.043679547,0.94544274,0.00018235654,0.00012636786,0.0007070624,0.0043205586,0.004790917,0.00069437036,0.000056101257],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9819625,0.0043077725,0.0013022355,0.00311665,0.0056975633,0.003613262],"domain_scores_gemma":[0.98989373,0.001003223,0.00039172618,0.0031113178,0.0005093721,0.005090598],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0019930287,0.0018731179,0.0036386396,0.0028283903,0.0011978217,0.00051444286,0.001692152,0.0004224691,0.0010444999],"category_scores_gemma":[0.00014894421,0.0013965032,0.0014379607,0.0031528063,0.001078305,0.00085628557,0.0007070663,0.0038714327,0.00041832853],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011180834,0.009310681,0.009959556,0.003994757,0.07266643,0.053400278,0.00024071685,0.000025079025,0.000009666094,0.00014668217,0.00044374427,0.83862156],"study_design_scores_gemma":[0.030712323,0.014364319,0.08831747,0.026317494,0.047761627,0.0007288778,0.00026318018,0.0009201842,0.000036743037,0.0006454146,0.7834882,0.0064441734],"about_ca_topic_score_codex":0.0009949416,"about_ca_topic_score_gemma":0.000016072332,"teacher_disagreement_score":0.8321774,"about_ca_system_score_codex":0.0005053105,"about_ca_system_score_gemma":0.0074348478,"threshold_uncertainty_score":0.9998687},"labels":[],"label_agreement":null},{"id":"W4311824021","doi":"10.1186/s13195-022-01136-y","title":"Associations of MRI-visible perivascular spaces with longitudinal cognitive decline across the Alzheimer’s disease spectrum","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Cerebrospinal fluid and hydrocephalus","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Key Research and Development Program of China; National Institute of Biomedical Imaging and Bioengineering; Shanghai Shen Kang Hospital Development Center; Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Servier; National Natural Science Foundation of China; Eisai; Genentech; IXICO; Northern California Institute for Research and Education; Fudan University; Novartis Pharmaceuticals Corporation; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; F. Hoffmann-La Roche; University of Southern California; Biogen; Shanghai Municipal Education Commission; Bristol-Myers Squibb; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Perivascular space; Cognitive decline; Disease; Alzheimer's disease; Cognition; Medicine; Psychology; Neuroscience; Pathology; Dementia","score_opus":0.14748790889383104,"score_gpt":0.40400300447679954,"score_spread":0.2565150955829685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311824021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9670289,0.020735962,0.000080182675,0.008923477,0.00015265695,0.001613168,0.0006224701,0.0000778953,0.00076526415],"genre_scores_gemma":[0.997178,0.0014551356,0.000024005363,0.00059002294,0.00017239404,0.0003265866,0.000032676136,0.000060060036,0.000161111],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99416167,0.0011578733,0.0003317876,0.00075467443,0.0025921885,0.0010018087],"domain_scores_gemma":[0.99750763,0.0011265003,0.00015708694,0.00067423534,0.00026922426,0.00026530257],"candidate_categories":["sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001913878,0.00026320896,0.0003405891,0.0001671105,0.0026133126,0.00024565487,0.0011125704,0.000039275124,0.0011503837],"category_scores_gemma":[0.0002615061,0.00018252248,0.00022418369,0.001740847,0.0010173845,0.00027288406,0.00071795844,0.0008820411,0.000061521525],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02911954,0.014558752,0.67444307,0.000067132365,0.0134410225,0.0018713837,0.044494133,0.0053623123,0.10011443,0.050206076,0.01348827,0.052833885],"study_design_scores_gemma":[0.008638879,0.0069650193,0.68243,0.00007958248,0.0008240804,0.00012392885,0.006089982,0.002830255,0.23209074,0.008318022,0.050132804,0.0014766762],"about_ca_topic_score_codex":0.000831332,"about_ca_topic_score_gemma":0.00017591415,"teacher_disagreement_score":0.13197632,"about_ca_system_score_codex":0.000058993923,"about_ca_system_score_gemma":0.00043494205,"threshold_uncertainty_score":0.9997627},"labels":[],"label_agreement":null},{"id":"W4312066037","doi":"10.1186/s13195-022-01134-0","title":"Association of neurofilament light chain with renal function: mechanisms and clinical implications","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; Servier; Eisai; Temple University; F. Hoffmann-La Roche; Biogen; University of California, San Diego; BioClinica; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Pfizer; Bristol-Myers Squibb; Eli Lilly and Company; National Institute on Aging; Alzheimer's Association; H. Lundbeck A/S; U.S. Department of Veterans Affairs","keywords":"Neurodegeneration; Medicine; Biomarker; Creatinine; Renal function; Internal medicine; Neurology; Cerebrospinal fluid; Cystatin C; Endocrinology; Physiology; Disease; Biology; Psychiatry; Genetics","score_opus":0.06621771843706073,"score_gpt":0.3690339572312682,"score_spread":0.3028162387942075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312066037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.969395,0.011845071,0.0014145586,0.014018116,0.00019663283,0.0013907958,0.000047146423,0.000022651573,0.0016700705],"genre_scores_gemma":[0.99557245,0.0023438856,0.00019451631,0.00024291467,0.00013273906,0.00023342231,0.0001128984,0.000021602735,0.001145544],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976368,0.0010092661,0.00020674356,0.00038665332,0.00044374852,0.00031681717],"domain_scores_gemma":[0.9991063,0.00009974414,0.00008190065,0.00037902224,0.00023765503,0.00009540211],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024446868,0.00009086268,0.00013187897,0.00008535169,0.00033908305,0.000017747989,0.00024421746,0.00009739844,0.00015906597],"category_scores_gemma":[0.000048067555,0.00007507594,0.00006337239,0.00024913898,0.00012977637,0.000003140166,0.0002505753,0.00037724883,0.0000042080037],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017217695,0.00044674287,0.01955362,0.0000026658865,0.0017040023,0.0000067291044,0.00006614628,0.0000072579624,0.9397577,0.0020562839,0.010770898,0.02390615],"study_design_scores_gemma":[0.004881714,0.020875959,0.049012553,0.000007835345,0.00013343686,0.00010203758,0.000510799,0.00007997136,0.35756078,0.0025603785,0.56381536,0.000459197],"about_ca_topic_score_codex":0.000021357773,"about_ca_topic_score_gemma":0.000014338397,"teacher_disagreement_score":0.58219695,"about_ca_system_score_codex":0.000017273913,"about_ca_system_score_gemma":0.00015705504,"threshold_uncertainty_score":0.3061508},"labels":[],"label_agreement":null},{"id":"W4312128886","doi":"10.1186/s13195-022-01142-0","title":"CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean; Montreal Neurological Institute and Hospital; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; McGill University; Douglas Mental Health University Institute","funders":"National Institute on Aging; Canadian Institutes of Health Research; Göteborgs Universitet","keywords":"Neurology; Geriatric psychiatry; Cognition; Psychology; Neocortex; Neuroscience; Medicine; Effects of sleep deprivation on cognitive performance; Internal medicine; Psychiatry","score_opus":0.10209578346674282,"score_gpt":0.4035197826239539,"score_spread":0.3014239991572111,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312128886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9840858,0.0037231448,0.000027369157,0.005641465,0.000053407166,0.004457437,0.000083934305,0.000056293215,0.0018711523],"genre_scores_gemma":[0.9930316,0.0010136575,0.00016904787,0.0029064768,0.000151472,0.0020259807,0.00014644154,0.00007208815,0.00048320496],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9935282,0.0013440552,0.00054377364,0.00100093,0.002120006,0.0014630584],"domain_scores_gemma":[0.9972491,0.00093127345,0.00007713363,0.00032256133,0.0006925501,0.00072735094],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0029953115,0.0003852835,0.0006388313,0.0011005601,0.0008018978,0.00021851741,0.0002485894,0.000108942484,0.0013317658],"category_scores_gemma":[0.0002738473,0.00035593632,0.000083370694,0.0015347648,0.00067563186,0.00037250514,0.00071440765,0.001494867,0.00008886605],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007977794,0.0017064005,0.6622265,0.00007820464,0.001463199,0.0004106004,0.00780876,0.0000024820388,0.019332433,0.000051547435,0.0067589744,0.29218313],"study_design_scores_gemma":[0.010682143,0.0064588645,0.9595492,0.00019178732,0.00012145877,0.00017914944,0.003537155,0.00049855345,0.013113549,0.00018697108,0.0050398936,0.00044128703],"about_ca_topic_score_codex":0.0002674923,"about_ca_topic_score_gemma":0.000027260563,"teacher_disagreement_score":0.2973227,"about_ca_system_score_codex":0.00012370275,"about_ca_system_score_gemma":0.0004922328,"threshold_uncertainty_score":0.99988925},"labels":[],"label_agreement":null},{"id":"W4313424031","doi":"10.1186/s13195-022-01138-w","title":"Subjective cognitive decline is a better marker for future cognitive decline in females than in males","year":2022,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute on Aging; Canadian Institutes of Health Research; Alzheimer Society Research Program","keywords":"Cognitive decline; Geriatric psychiatry; Neurology; Cognitive aging; Cognition; Medicine; Gerontology; Psychology; Psychiatry; Dementia; Internal medicine; Disease","score_opus":0.10456307827804472,"score_gpt":0.4270576905960003,"score_spread":0.32249461231795556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313424031","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9654773,0.011915587,0.00007382814,0.014841811,0.0001084431,0.005568018,0.000344341,0.00003741088,0.0016332989],"genre_scores_gemma":[0.9855523,0.0021205614,0.00017952459,0.0052892244,0.00044498875,0.0050890497,0.00043922922,0.00010657785,0.00077853247],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99315655,0.0015878679,0.0005972042,0.0010405405,0.0020702318,0.0015476174],"domain_scores_gemma":[0.995898,0.002196372,0.00009951918,0.00032741402,0.0011741371,0.00030457403],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00472458,0.00040285953,0.0006501195,0.001380792,0.00046045013,0.00009814017,0.00041713455,0.00016060936,0.0034674057],"category_scores_gemma":[0.00035498955,0.00036075493,0.00028083974,0.0019456277,0.00048748023,0.00024338497,0.0006528148,0.0017237281,0.0000801807],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020043224,0.0020231549,0.8912291,0.00003453887,0.0010394325,0.00034668169,0.003101246,2.9183533e-7,0.0008501614,0.00003805138,0.0001554603,0.08113867],"study_design_scores_gemma":[0.014010393,0.0039671445,0.9470678,0.00016900251,0.00008417209,0.000042211734,0.014744337,0.00017667358,0.007689544,0.0014773745,0.010219206,0.00035213187],"about_ca_topic_score_codex":0.000598441,"about_ca_topic_score_gemma":0.00087713415,"teacher_disagreement_score":0.08078653,"about_ca_system_score_codex":0.00018015792,"about_ca_system_score_gemma":0.00066272245,"threshold_uncertainty_score":0.9998844},"labels":[],"label_agreement":null},{"id":"W4313559585","doi":"10.1186/s13195-022-01157-7","title":"Altered metabolic connectivity within the limbic cortico-striato-thalamo-cortical circuit in presymptomatic and symptomatic behavioral variant frontotemporal dementia","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Beijing Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Frontotemporal dementia; Neuroscience; Psychology; Dementia; Functional connectivity; Medicine; Pathology; Disease","score_opus":0.14300402414961744,"score_gpt":0.40667636370983096,"score_spread":0.2636723395602135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313559585","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866237,0.0071667484,0.000050121773,0.0016467869,0.00016103321,0.0037060073,0.000013140616,0.00015432274,0.00047810999],"genre_scores_gemma":[0.9972359,0.0010922246,0.00006022174,0.0001905607,0.0001468256,0.0009854168,0.00004539644,0.000072615694,0.00017082917],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99290633,0.002156409,0.0007696982,0.00076857524,0.0020138859,0.0013851217],"domain_scores_gemma":[0.99719954,0.0010799126,0.00012144547,0.00079370453,0.0003288852,0.00047654012],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0060161175,0.00035859022,0.0006810613,0.0007066465,0.00047670078,0.00028519932,0.00043741654,0.00016253591,0.0005233104],"category_scores_gemma":[0.00040495387,0.0002491876,0.00016434472,0.0016344063,0.0007156477,0.0003140736,0.00031722695,0.0012147336,0.0002061148],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011193577,0.0021689066,0.93040735,0.00008746945,0.00337551,0.0005666285,0.004535691,0.000003058267,0.01428757,0.002049406,0.0008549711,0.040544108],"study_design_scores_gemma":[0.005894618,0.0016262892,0.97896045,0.00013751416,0.00047949844,0.00010567526,0.0013755211,0.0046490077,0.0036596567,0.0024540753,0.00037586727,0.00028181716],"about_ca_topic_score_codex":0.0009911675,"about_ca_topic_score_gemma":0.00021270373,"teacher_disagreement_score":0.048553135,"about_ca_system_score_codex":0.000060974297,"about_ca_system_score_gemma":0.0005183675,"threshold_uncertainty_score":0.99999607},"labels":[],"label_agreement":null},{"id":"W4319442566","doi":"10.1186/s13195-023-01178-w","title":"Initial levels of β-amyloid and tau deposition have distinct effects on longitudinal tau accumulation in Alzheimer’s disease","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Servier; Eisai; Genentech; IXICO; National Natural Science Foundation of China; Pfizer; Novartis Pharmaceuticals Corporation; F. Hoffmann-La Roche; Shenzhen Bay Laboratory; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; National Institute on Aging; Alzheimer's Association","keywords":"Entorhinal cortex; Psychology; Temporal lobe; Alzheimer's disease; Internal medicine; Neurodegeneration; Apolipoprotein E; Temporal cortex; Tau pathology; Senile plaques; Neuroscience; Longitudinal study; Disease; Oncology; Hippocampus; Medicine; Pathology","score_opus":0.23068759644437076,"score_gpt":0.4601775724755198,"score_spread":0.22948997603114907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319442566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9724884,0.022922833,0.000020470052,0.0012036395,0.000072431976,0.00268533,0.00013045642,0.00009883503,0.00037760535],"genre_scores_gemma":[0.9975275,0.0012703594,0.000044920023,0.0000774519,0.00023252286,0.00042729022,0.00032627804,0.00007612002,0.00001759108],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9953409,0.0007398485,0.0004445082,0.00074314466,0.0017363343,0.0009953073],"domain_scores_gemma":[0.99698776,0.0011124398,0.00009086545,0.0006144479,0.00036210837,0.00083235535],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010232284,0.00034988808,0.0005236487,0.0010697698,0.00027883632,0.000075621356,0.000197916,0.00014568164,0.00013204351],"category_scores_gemma":[0.0002472987,0.00029234213,0.0001662036,0.0011013472,0.0004159777,0.00029153182,0.00014557244,0.00055946474,0.00014992066],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.017574962,0.0022701067,0.67669755,0.00017091045,0.013366319,0.0032291913,0.00068585185,0.000045648078,0.0022385344,0.00026674176,0.0011832459,0.28227094],"study_design_scores_gemma":[0.0061075995,0.0018628003,0.97224224,0.00033218833,0.0003993237,0.000011574657,0.00007733814,0.0015249288,0.016129194,0.001016471,0.000060326456,0.00023602902],"about_ca_topic_score_codex":0.00063366967,"about_ca_topic_score_gemma":0.00006884709,"teacher_disagreement_score":0.29554468,"about_ca_system_score_codex":0.00009282043,"about_ca_system_score_gemma":0.0004352968,"threshold_uncertainty_score":0.99995285},"labels":[],"label_agreement":null},{"id":"W4360866215","doi":"10.1186/s13195-023-01207-8","title":"Therapeutic preference for Alzheimer’s disease treatments: a discrete choice experiment with caregivers and neurologists","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute on Aging; Eisai Incorporated; University of California, San Francisco; Eisai","keywords":"Medicine; Neurology; Preference; Geriatric psychiatry; Biomarker; Psychiatry","score_opus":0.23967961145735056,"score_gpt":0.4424321363352577,"score_spread":0.20275252487790713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4360866215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9488752,0.03273122,0.00010318916,0.0089318175,0.00007093642,0.007478681,0.00007227056,0.00024956703,0.0014871387],"genre_scores_gemma":[0.9897669,0.0054635745,0.0000883085,0.00035439365,0.000107792206,0.0030707186,0.00013887735,0.00007289237,0.00093655044],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99632734,0.00034732535,0.00020418598,0.0008168554,0.0011676423,0.0011366662],"domain_scores_gemma":[0.997688,0.00059516384,0.00004509516,0.0005618191,0.00045016286,0.000659744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006617267,0.0003125546,0.00032613377,0.0003866519,0.00043336008,0.00013648329,0.00025354399,0.00007058286,0.00018239119],"category_scores_gemma":[0.00006422978,0.00020953619,0.00011252146,0.000695261,0.00062985823,0.00020104885,0.00013110234,0.0003198219,0.0000643034],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.043211382,0.0025299317,0.3392055,0.00015898206,0.017522058,0.00073837565,0.0067264987,0.000009569961,0.019964851,0.0010215546,0.006146598,0.5627647],"study_design_scores_gemma":[0.019592514,0.018760666,0.8652234,0.00016652823,0.0013049492,0.000024494531,0.0024501968,0.00089061033,0.019667575,0.0008512307,0.07039506,0.00067278283],"about_ca_topic_score_codex":0.00027763535,"about_ca_topic_score_gemma":0.000019210289,"teacher_disagreement_score":0.5620919,"about_ca_system_score_codex":0.000042723495,"about_ca_system_score_gemma":0.00033808773,"threshold_uncertainty_score":0.85446376},"labels":[],"label_agreement":null},{"id":"W4366599813","doi":"10.1186/s13195-023-01228-3","title":"Functional gradients of the medial parietal cortex in a healthy cohort with family history of sporadic Alzheimer’s disease","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Montreal Neurological Institute and Hospital","funders":"Alzheimerfonden; Vetenskapsrådet; Karolinska Institutet","keywords":"Neurology; Geriatric psychiatry; Disease; Family history; Neuroscience; Medicine; Cohort; Psychology; Psychiatry; Pathology; Internal medicine","score_opus":0.20427419421676393,"score_gpt":0.35359797494451567,"score_spread":0.14932378072775174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366599813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98326135,0.008734376,0.0000028526406,0.004703528,0.0010501475,0.0013928668,0.000060633458,0.00005582894,0.0007384039],"genre_scores_gemma":[0.9972215,0.0011326119,0.000007214168,0.0009994527,0.00010286351,0.00027876094,0.000010377944,0.00003952369,0.00020769433],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99517673,0.00083877874,0.00039533054,0.00069110194,0.0022777456,0.0006203293],"domain_scores_gemma":[0.9950811,0.0036669716,0.00016110753,0.00063097454,0.00026865993,0.0001911326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015265753,0.00020985126,0.00035389754,0.00048438436,0.00021498039,0.000010623317,0.00053647027,0.000061456296,0.00009653543],"category_scores_gemma":[0.0012208252,0.00014687012,0.00013651224,0.0018371402,0.0019457613,0.00018827275,0.00019969707,0.00053314946,0.000042830907],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.031045891,0.0026608044,0.65296143,0.00007191858,0.0016359742,0.0002193987,0.004843046,0.0004962722,0.099601954,0.0061879535,0.1883691,0.011906265],"study_design_scores_gemma":[0.0018647334,0.0008032982,0.9770816,0.000036807425,0.00004824293,0.000003915859,0.00015718344,0.00024771475,0.0026614377,0.0008409225,0.016077774,0.00017637672],"about_ca_topic_score_codex":0.0006183309,"about_ca_topic_score_gemma":0.0001758719,"teacher_disagreement_score":0.32412016,"about_ca_system_score_codex":0.00017777031,"about_ca_system_score_gemma":0.0014404188,"threshold_uncertainty_score":0.71692383},"labels":[],"label_agreement":null},{"id":"W4375855965","doi":"10.1186/s13195-023-01232-7","title":"Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer’s disease","year":2023,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universität zu Lübeck; NIHR Oxford Biomedical Research Centre; National Natural Science Foundation of China; Deutsche Forschungsgemeinschaft; Parkinson's UK; National Institute for Health and Care Research; Alzheimer Society; Cure Alzheimer's Fund; National Science Foundation","keywords":"dNaM; Epigenome; Epigenetics; DNA methylation; Entorhinal cortex; CpG site; Biology; Methylation; Genetics; Genetic association; Bioinformatics; Single-nucleotide polymorphism; Neuroscience; Gene; Hippocampus; Gene expression; Genotype","score_opus":0.24467006407498199,"score_gpt":0.4311838912147881,"score_spread":0.18651382713980613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4375855965","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011650181,0.9835021,0.0002395434,0.00013764198,0.00047648363,0.0037818768,0.00009994092,0.000042432013,0.00006979388],"genre_scores_gemma":[0.032916263,0.96293133,0.00004961219,0.00002072379,0.0009908658,0.0008122666,0.0016801447,0.0002131325,0.0003856299],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9927438,0.0020848971,0.0011387655,0.0013715498,0.0015827372,0.0010782318],"domain_scores_gemma":[0.99693763,0.00074150815,0.00050175213,0.0009897575,0.0004664833,0.00036288955],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003408809,0.0006807867,0.0011768735,0.00077470415,0.00034552166,0.00024790873,0.0008053088,0.0006539749,0.000069773414],"category_scores_gemma":[0.00055312034,0.00060967787,0.0005730753,0.0009984558,0.00007847279,0.000022908423,0.00036610593,0.0008811125,0.00011588747],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006740011,0.0032359327,0.013724724,0.00068287435,0.015997274,0.00012969704,0.00089166505,0.00006182221,0.0059025665,0.000117081676,0.0012808437,0.9573015],"study_design_scores_gemma":[0.0019146687,0.00090549764,0.018495034,0.00057234813,0.0014994012,3.261278e-7,0.000078893994,0.000042761825,0.00057699543,0.00024394282,0.9745566,0.0011135094],"about_ca_topic_score_codex":0.00032277222,"about_ca_topic_score_gemma":0.00031445688,"teacher_disagreement_score":0.9732758,"about_ca_system_score_codex":0.00023385312,"about_ca_system_score_gemma":0.0007271097,"threshold_uncertainty_score":0.99963546},"labels":[],"label_agreement":null},{"id":"W4379259455","doi":"10.1186/s13195-023-01251-4","title":"APOE4 carrier status determines association between white matter disease and grey matter atrophy in early-stage dementia","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Ministry of Education, India; National Medical Research Council; Medical Research Council; Nanyang Technological University; Lee Kong Chian School of Medicine, Nanyang Technological University; Ministry of Education - Singapore","keywords":"Hyperintensity; Grey matter; White matter; Dementia; Psychology; Medicine; Pathology; Magnetic resonance imaging; Disease; Radiology","score_opus":0.06576705407617764,"score_gpt":0.3791157044281727,"score_spread":0.3133486503519951,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379259455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99042046,0.0021060482,0.000006753233,0.004575741,0.000057373858,0.001505995,0.00011615812,0.000053854557,0.00115759],"genre_scores_gemma":[0.9893104,0.0016334632,0.00003387769,0.00060797506,0.00021713022,0.00036649086,0.0001852993,0.000071314986,0.0075740525],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9954008,0.00062326336,0.0003651242,0.00060048717,0.0015672249,0.0014431267],"domain_scores_gemma":[0.99818575,0.00030765551,0.0000652358,0.00040776233,0.00041949443,0.00061412255],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0016443904,0.00024490323,0.00034582577,0.0008662223,0.00021762076,0.00023990679,0.0001835477,0.00011583461,0.0026787433],"category_scores_gemma":[0.00007985267,0.00021113546,0.00011092905,0.001034343,0.00017402871,0.00033642718,0.00022717485,0.0005900827,0.0015230519],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005216516,0.00009743063,0.9812725,0.000043255124,0.0011554552,0.00012926824,0.000645104,3.3486006e-7,0.0008316359,0.0000024000672,0.007937573,0.0073633436],"study_design_scores_gemma":[0.002685224,0.00035662606,0.9812708,0.00005623444,0.00016595819,8.3810767e-7,0.00017652905,0.00003729639,0.00078482536,0.0001622161,0.014104618,0.00019883363],"about_ca_topic_score_codex":0.0005549379,"about_ca_topic_score_gemma":0.00004632881,"teacher_disagreement_score":0.00716451,"about_ca_system_score_codex":0.000110559646,"about_ca_system_score_gemma":0.00018133607,"threshold_uncertainty_score":0.9992544},"labels":[],"label_agreement":null},{"id":"W4380871419","doi":"10.1186/s13195-023-01250-5","title":"Immediate word recall in cognitive assessment can predict dementia using machine learning techniques","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Thompson Rivers University; University of Northern British Columbia","funders":"","keywords":"Recall; Dementia; Cognition; Cognitive psychology; Artificial intelligence; Psychology; Word (group theory); Computer science; Machine learning; Natural language processing; Linguistics; Medicine; Neuroscience","score_opus":0.16970132734156665,"score_gpt":0.46832371098647674,"score_spread":0.2986223836449101,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380871419","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833175,0.0053470843,0.00013813011,0.0024529565,0.000085178246,0.0032730242,0.00003007646,0.0003364352,0.0050196014],"genre_scores_gemma":[0.9869774,0.009968155,0.0007699579,0.00025220102,0.00020015653,0.00067031925,0.00032407383,0.000093757204,0.00074395596],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.994041,0.0012490911,0.00048427997,0.0007148829,0.002001006,0.0015097342],"domain_scores_gemma":[0.9979206,0.00060655846,0.000077762576,0.0003152791,0.0006936447,0.00038620524],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005238515,0.00029937434,0.00044195759,0.0015894492,0.00037472986,0.00013143914,0.00028770947,0.00015642859,0.0010747095],"category_scores_gemma":[0.00025003974,0.0002594925,0.00014019637,0.0025241198,0.00035374894,0.00019477264,0.00032809144,0.0019473222,0.00009212377],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011966993,0.00062664266,0.62033355,0.00003573696,0.0017571845,0.00055957417,0.0006621871,0.0000018851623,0.050090954,0.000023550574,0.0004791866,0.32423288],"study_design_scores_gemma":[0.010600191,0.0047942,0.7995147,0.0009588696,0.00035800927,0.0000497927,0.0027099987,0.0067152567,0.1524298,0.0007296051,0.020437676,0.00070185843],"about_ca_topic_score_codex":0.0017522881,"about_ca_topic_score_gemma":0.00019871024,"teacher_disagreement_score":0.323531,"about_ca_system_score_codex":0.00016733489,"about_ca_system_score_gemma":0.0007758334,"threshold_uncertainty_score":0.99998575},"labels":[],"label_agreement":null},{"id":"W4380988136","doi":"10.1186/s13195-023-01244-3","title":"Shared genetic risk loci between Alzheimer’s disease and related dementias, Parkinson’s disease, and amyotrophic lateral sclerosis","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Aging; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Krembil Foundation; Simons Foundation Autism Research Initiative; Simons Foundation","keywords":"Genome-wide association study; Amyotrophic lateral sclerosis; Locus (genetics); Genetics; Genetic association; Disease; Biology; Medicine; Single-nucleotide polymorphism; Internal medicine; Genotype; Gene","score_opus":0.14510871394909353,"score_gpt":0.3635634628337176,"score_spread":0.21845474888462407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380988136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91476977,0.07410963,0.000005801956,0.0077178692,0.000076610864,0.0026480407,0.00026388542,0.0003284091,0.00008000611],"genre_scores_gemma":[0.917853,0.07978748,0.00026970162,0.0002140006,0.0004077027,0.00051058654,0.0003962551,0.00019173855,0.00036954955],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9921542,0.0013044055,0.0007603535,0.0015397364,0.0023178074,0.0019234882],"domain_scores_gemma":[0.99495,0.00051165296,0.00014013365,0.001221342,0.00047739738,0.0026994583],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0018339759,0.0005761996,0.0007348185,0.00088553247,0.0009929984,0.00040265574,0.00053801155,0.00026593116,0.0009825821],"category_scores_gemma":[0.00026944221,0.0004772306,0.00023359229,0.0018435161,0.0011902554,0.00039229885,0.0007375512,0.0014089548,0.0005562173],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002978308,0.00027845282,0.81325436,0.00007802989,0.0067549814,0.00064247026,0.0007454711,0.00001557315,0.003884312,0.000052566458,0.0130825825,0.1582329],"study_design_scores_gemma":[0.0042141406,0.00065312354,0.9815702,0.00020311374,0.0010088041,0.0000069795624,0.000039009552,0.0016257479,0.00016430987,0.0021907222,0.007843161,0.0004806935],"about_ca_topic_score_codex":0.0007746591,"about_ca_topic_score_gemma":0.000013869668,"teacher_disagreement_score":0.16831583,"about_ca_system_score_codex":0.00009177908,"about_ca_system_score_gemma":0.00037410884,"threshold_uncertainty_score":0.9999307},"labels":[],"label_agreement":null},{"id":"W4381433183","doi":"10.1186/s13195-023-01257-y","title":"White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Rehabilitation Institute; Health Sciences Centre; University of Calgary; Centre for Addiction and Mental Health; Western University; Nova Scotia Health Authority; Toronto Dementia Research Alliance; The Scarborough Hospital; Parkwood Institute; York University; Baycrest Hospital; Lawson Health Research Institute; Bruyère; University of Ottawa; Toronto Western Hospital; Discovery Centre; McMaster University; London Health Sciences Centre; Robarts Clinical Trials; Thunder Bay Regional Research Institute; Queen's University; University of Toronto; Sunnybrook Health Science Centre; St. Michael's Hospital; University Health Network; Heart and Stroke Foundation","funders":"Faculty of Health Sciences, Queen's University; University of Toronto Scarborough; Cumming School of Medicine, University of Calgary; Schulich School of Medicine and Dentistry, Western University; Temerty Family Foundation; Queen's University; York University; Schulich School of Medicine and Dentistry; University of Toronto; Strong; Sunnybrook Research Institute; Department of Psychiatry, University of Toronto; Wellcome Trust; Centre for Addiction and Mental Health Foundation; McMaster University; London Health Sciences Centre; University of Ottawa; Northwestern University; Ontario Brain Institute; Central Michigan University; Robarts Research Institute; London Health Sciences Foundation","keywords":"Hyperintensity; Apathy; White matter; Frontotemporal dementia; Dementia; Psychology; Cingulum (brain); Medicine; Atrophy; Neuroscience; Disease; Pathology; Cognition; Magnetic resonance imaging; Fractional anisotropy; Radiology","score_opus":0.052641859827565966,"score_gpt":0.33065736849573435,"score_spread":0.2780155086681684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381433183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907807,0.0027016308,0.000003760394,0.005101683,0.0000358704,0.0009969414,0.000014053397,0.00006440258,0.0003009713],"genre_scores_gemma":[0.9955099,0.002505974,0.000011387642,0.000884151,0.00006251936,0.00019705317,0.000037133683,0.000055486806,0.0007363798],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9966748,0.00084479275,0.00020325492,0.0005758934,0.00096185465,0.00073943724],"domain_scores_gemma":[0.9985471,0.00034759493,0.00003246573,0.00027161214,0.00049991976,0.00030134362],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007147854,0.00021835792,0.00035853832,0.0005816368,0.00024117417,0.00014464813,0.00010523622,0.00007461152,0.0002299967],"category_scores_gemma":[0.00011941621,0.00015564068,0.000054495187,0.001169478,0.00068456284,0.00013956003,0.00015402507,0.00066507247,0.00005978864],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006793461,0.00026091776,0.9945042,0.000023182592,0.00066510844,0.00019158129,0.0005004439,0.0000018151785,0.00042846127,0.000018981005,0.0009114668,0.0018144994],"study_design_scores_gemma":[0.0032115954,0.0011052812,0.99337935,0.00009408703,0.00009687189,0.000041563413,0.0010836227,0.0003533148,0.00018057192,0.00006160557,0.00022571275,0.0001664301],"about_ca_topic_score_codex":0.00006662024,"about_ca_topic_score_gemma":0.000060561575,"teacher_disagreement_score":0.004729228,"about_ca_system_score_codex":0.000019891579,"about_ca_system_score_gemma":0.00011669533,"threshold_uncertainty_score":0.63468426},"labels":[],"label_agreement":null},{"id":"W4385630947","doi":"10.1186/s13195-023-01280-z","title":"Beta to theta power ratio in EEG periodic components as a potential biomarker in mild cognitive impairment and Alzheimer’s dementia","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Baycrest Hospital; Health Sciences Centre; Toronto Dementia Research Alliance; University of Toronto; University Health Network; St. Michael's Hospital; Sunnybrook Health Science Centre; Centre for Addiction and Mental Health","funders":"Fondation Brain Canada; Biogen","keywords":"Electroencephalography; Aperiodic graph; Dementia; BETA (programming language); Audiology; Beta Rhythm; Psychology; Cognition; Internal medicine; Neuroscience; Mathematics; Medicine; Combinatorics; Computer science","score_opus":0.11527223451642354,"score_gpt":0.4114438400477125,"score_spread":0.29617160553128896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385630947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9705464,0.015214392,0.000010832811,0.007073024,0.000111410656,0.005075173,0.000032844513,0.000075916374,0.0018599668],"genre_scores_gemma":[0.9944044,0.0030939926,0.000044299006,0.0008786654,0.000040249794,0.0009910376,0.00017536548,0.000080607,0.00029137862],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9935127,0.0010575748,0.00062025123,0.0010334452,0.0020668954,0.0017091183],"domain_scores_gemma":[0.9980293,0.00032651518,0.000057486424,0.0004545342,0.0004825117,0.00064966385],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0035308988,0.0004082964,0.00056399294,0.002276562,0.00030575044,0.0002273283,0.0003484926,0.00014841734,0.0017832048],"category_scores_gemma":[0.00009078216,0.0003559028,0.00015377697,0.002519071,0.00046069772,0.00027568804,0.0005154118,0.00079164456,0.0011463106],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020404851,0.0054386063,0.71370345,0.00006141253,0.013188343,0.0032875747,0.009716092,0.0000053454337,0.09851674,0.00016376779,0.009557763,0.12595604],"study_design_scores_gemma":[0.0107044885,0.002755146,0.97264624,0.0002710935,0.00020858506,0.00004148014,0.002714021,0.00036506102,0.00645845,0.00022461277,0.003247911,0.0003629164],"about_ca_topic_score_codex":0.0014440283,"about_ca_topic_score_gemma":0.00018283969,"teacher_disagreement_score":0.25894278,"about_ca_system_score_codex":0.000075735195,"about_ca_system_score_gemma":0.0004040352,"threshold_uncertainty_score":0.9998893},"labels":[],"label_agreement":null},{"id":"W4386375248","doi":"10.1186/s13195-023-01294-7","title":"A plasma protein signature associated with cognitive function in men without severe cognitive impairment","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; Deakin University; Genome British Columbia","keywords":"Cognition; Medicine; Neurology; Disease; Dementia; Apolipoprotein E; Internal medicine; Alzheimer's disease; Biomarker; Bioinformatics; Oncology; Clinical psychology; Biology; Psychiatry; Genetics","score_opus":0.0748105355102709,"score_gpt":0.37445353615763416,"score_spread":0.29964300064736327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386375248","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784369,0.008148327,0.000003938716,0.0009749083,0.00002409223,0.008026681,0.00016414498,0.0002639231,0.0039571165],"genre_scores_gemma":[0.99457854,0.00061923027,0.000015441557,0.00013236166,0.000097907636,0.0027578326,0.00092239206,0.000114792834,0.0007614894],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99407595,0.0009841484,0.00031381848,0.000839207,0.0022824574,0.0015044243],"domain_scores_gemma":[0.9970885,0.00070999307,0.00008933385,0.00031699738,0.0011434475,0.0006517359],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014794706,0.00040798995,0.0005285598,0.0009007496,0.00035292187,0.00009384909,0.00016986448,0.00026131934,0.00043844574],"category_scores_gemma":[0.0002732008,0.00029372002,0.00013576644,0.0027397408,0.00042131412,0.00028837245,0.00010999149,0.0012804237,0.0006715095],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.21225202,0.01537346,0.37928498,0.00015214134,0.23825665,0.010417072,0.0077408613,0.000017413446,0.0032759197,0.0001363049,0.012566182,0.12052701],"study_design_scores_gemma":[0.083987616,0.026204541,0.8536679,0.003861008,0.0019812281,0.00007147696,0.009974795,0.0014474887,0.016114578,0.00110848,0.0004262893,0.0011546023],"about_ca_topic_score_codex":0.00030979508,"about_ca_topic_score_gemma":0.00013479419,"teacher_disagreement_score":0.47438294,"about_ca_system_score_codex":0.00020884608,"about_ca_system_score_gemma":0.00108732,"threshold_uncertainty_score":0.9999515},"labels":[],"label_agreement":null},{"id":"W4386546537","doi":"10.1186/s13195-023-01265-y","title":"REM sleep is associated with the volume of the cholinergic basal forebrain in aMCI individuals","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut Universitaire de Gériatrie de Montréal; Health and Social Services Centre University Institute of Geriatrics of Sherbrooke; Canadian Sleep & Circadian Network; Université de Sherbrooke; Université Laval; Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Fonds de Recherche du Québec - Santé; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Réseau en Bio-Imagerie du Quebec","keywords":"Basal forebrain; Neurology; Cholinergic neuron; Neuroscience; Sleep (system call); Basal (medicine); Cholinergic; Medicine; Psychology; Internal medicine; Computer science","score_opus":0.18626237974206364,"score_gpt":0.38465891256786744,"score_spread":0.1983965328258038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386546537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97434837,0.00058216363,0.0000039595293,0.021868117,0.00009375872,0.0013532792,0.00006238217,0.00006540398,0.0016225674],"genre_scores_gemma":[0.99616134,0.0003506694,0.000004356492,0.001268544,0.00007845969,0.00032107302,0.000005999812,0.00006167144,0.0017478811],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9921846,0.0026448742,0.00034318308,0.0006154349,0.0029545054,0.0012574502],"domain_scores_gemma":[0.9958104,0.002595874,0.00011470684,0.0010681461,0.0002798318,0.00013104414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005228988,0.00022161438,0.00029938392,0.0005060624,0.00060087664,0.0001592992,0.0022132972,0.00014738229,0.00036760804],"category_scores_gemma":[0.0013992474,0.00011334555,0.00013404022,0.006868655,0.0012387946,0.00022132133,0.00048317786,0.0012704104,0.00017860859],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020712856,0.0022251313,0.3075931,0.000037149854,0.0021173847,0.00034622368,0.036712658,0.0013941047,0.18792555,0.0051215338,0.27323422,0.18122165],"study_design_scores_gemma":[0.0050879717,0.00096623047,0.44206396,0.00012947648,0.000034784138,0.000008438205,0.001504523,0.0114103,0.50016314,0.005673676,0.032385577,0.00057191896],"about_ca_topic_score_codex":0.00038165605,"about_ca_topic_score_gemma":0.00020598968,"teacher_disagreement_score":0.31223762,"about_ca_system_score_codex":0.00005045654,"about_ca_system_score_gemma":0.00026516276,"threshold_uncertainty_score":0.55193716},"labels":[],"label_agreement":null},{"id":"W4386639439","doi":"10.1186/s13195-023-01299-2","title":"Is later-life depression a risk factor for Alzheimer’s disease or a prodromal symptom: a study using post-mortem human brain tissue?","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Medical Research Council; Elizabeth Blackwell Institute for Health Research, University of Bristol; David Telling Charitable Trust; University of Bristol; UK Dementia Research Institute; National Institute for Health and Care Research; Alzheimer's Society; BRACE; Wellcome Trust; Fondation Brain Canada","keywords":"Depression (economics); Neurology; Geriatric psychiatry; Medicine; Risk factor; Disease; Psychiatry; Late life depression; Pathology","score_opus":0.25791255813212305,"score_gpt":0.5067465055182161,"score_spread":0.24883394738609305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386639439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9801884,0.0037281075,0.000023838777,0.0026336547,0.000099237324,0.012506637,0.00040532686,0.0002792972,0.00013547286],"genre_scores_gemma":[0.9945482,0.00029691804,0.00010674228,0.00062225293,0.0004152815,0.0019241022,0.00013761861,0.00018390613,0.0017650049],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9925016,0.0011791628,0.00061919633,0.0012840005,0.0026088576,0.0018071942],"domain_scores_gemma":[0.9954289,0.0008280748,0.00013764224,0.001043157,0.0012731786,0.0012890083],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0027311281,0.00048374198,0.0006384019,0.0010469091,0.0012219248,0.0002886706,0.00056399935,0.00015461273,0.0022726236],"category_scores_gemma":[0.00063485623,0.0003458587,0.00028507886,0.0015553981,0.00029571963,0.00033382923,0.00041183914,0.00077998306,0.0003253685],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02073982,0.0054201595,0.69032645,0.00014272083,0.01026096,0.0010310555,0.008644435,0.0000014462267,0.084830545,0.000013221189,0.009572855,0.1690163],"study_design_scores_gemma":[0.01350284,0.010975642,0.9441997,0.00022521763,0.0009765005,0.000017372924,0.0028652921,0.0010948337,0.018414129,0.00016891529,0.0069648335,0.0005947466],"about_ca_topic_score_codex":0.00054356613,"about_ca_topic_score_gemma":0.0000615958,"teacher_disagreement_score":0.2538732,"about_ca_system_score_codex":0.00007423193,"about_ca_system_score_gemma":0.0010458448,"threshold_uncertainty_score":0.9998993},"labels":[],"label_agreement":null},{"id":"W4386981239","doi":"10.1186/s13195-023-01292-9","title":"Effects of computerized cognitive training on structure‒function coupling and topology of multiple brain networks in people with mild cognitive impairment: a randomized controlled trial","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Fujian University of Traditional Chinese Medicine","keywords":"Montreal Cognitive Assessment; Cognition; Neuropsychology; Stroop effect; Default mode network; Psychology; Audiology; Medicine; Neuroscience; Cognitive impairment","score_opus":0.07436611628817187,"score_gpt":0.3495507254049476,"score_spread":0.2751846091167757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386981239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875324,0.0010232248,0.0006749953,0.00084005605,0.00027042328,0.009564177,0.00001870909,0.00004709788,0.000028910032],"genre_scores_gemma":[0.9976369,0.0004728664,0.000019472158,0.0005168785,0.000100645564,0.0012011543,0.000009374002,0.000031762087,0.000010940837],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99529505,0.002420311,0.00047522507,0.00060868147,0.00067720644,0.0005235215],"domain_scores_gemma":[0.85560024,0.14379196,0.00019898075,0.00010577786,0.00024082848,0.00006219543],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0028637818,0.00025068622,0.001468744,0.00064035406,0.00023055582,0.000028320772,0.00012581458,0.00014239411,0.000016009277],"category_scores_gemma":[0.010668912,0.0001804065,0.0001521632,0.001141034,0.0009785013,0.00010798963,0.00008979475,0.00057381013,0.0000014084354],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9757148,0.0002689595,0.00023132421,0.000020054858,0.00094451074,0.000015407157,0.0039044162,0.0005708324,0.015599482,0.00020859203,0.000036042853,0.0024855644],"study_design_scores_gemma":[0.9283399,0.004944694,0.0048418115,0.00022844858,0.0000998969,0.0000029151183,0.0009317399,0.03959209,0.020448538,0.00039528252,0.000005496262,0.0001691744],"about_ca_topic_score_codex":0.00015790071,"about_ca_topic_score_gemma":0.00012026859,"teacher_disagreement_score":0.14137165,"about_ca_system_score_codex":0.000021288077,"about_ca_system_score_gemma":0.00012143754,"threshold_uncertainty_score":0.99766463},"labels":[],"label_agreement":null},{"id":"W4387336768","doi":"10.1186/s13195-023-01309-3","title":"In vivo cortical diffusion imaging relates to Alzheimer’s disease neuropathology","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Advanced Neuroimaging Techniques and Applications","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; F. Hoffmann-La Roche; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; University of California, San Diego; BioClinica; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Pfizer; National Institute on Aging; Alzheimer's Association","keywords":"Neuropathology; Cerebral amyloid angiopathy; Diffusion MRI; Pathology; Neuroimaging; Neuroscience; White matter; Neurology; Neurodegeneration; Medicine; Lewy body; Alzheimer's disease; Psychology; Dementia; Disease; Magnetic resonance imaging; Radiology","score_opus":0.23715601182103507,"score_gpt":0.48136043609076024,"score_spread":0.24420442426972516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387336768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86913383,0.006170823,0.0006848872,0.118163764,0.0001705226,0.0034167252,0.000027326721,0.0010020755,0.0012300356],"genre_scores_gemma":[0.99026465,0.0032340758,0.0012208688,0.003980191,0.00015699601,0.00065547426,0.00001848519,0.00009639796,0.00037287062],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99746704,0.0002789297,0.00029803521,0.00065027183,0.0005255206,0.00078023056],"domain_scores_gemma":[0.9981337,0.00041219423,0.000027094073,0.0007821056,0.00015724507,0.00048764268],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007068523,0.00018097574,0.00024702272,0.00064732257,0.00022786896,0.000032875017,0.000288087,0.000048060174,0.00019946737],"category_scores_gemma":[0.00019384062,0.00015824352,0.000081797676,0.0016550124,0.00024722124,0.000119464836,0.00026740762,0.00077299465,0.00043636758],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027688635,0.0015134243,0.12526412,0.000020093657,0.00016841672,0.006017601,0.0012754626,0.000057357895,0.6057705,0.0086604655,0.12562598,0.12285771],"study_design_scores_gemma":[0.0032098265,0.0009600301,0.49452075,0.00018804421,0.00015868449,0.00017622334,0.00021384927,0.008475394,0.046768535,0.024119848,0.42047173,0.0007370807],"about_ca_topic_score_codex":0.0000491152,"about_ca_topic_score_gemma":0.000002225388,"teacher_disagreement_score":0.559002,"about_ca_system_score_codex":0.000027466142,"about_ca_system_score_gemma":0.00009397958,"threshold_uncertainty_score":0.64529836},"labels":[],"label_agreement":null},{"id":"W4387369749","doi":"10.1186/s13195-023-01317-3","title":"Cognitive impairment indicator for the neuropsychological test batteries in the Canadian Longitudinal Study on Aging: definition and evidence for validity","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Dalhousie University; University of Ottawa; McGill University Health Centre; McMaster University; McGill University; Impact; University of Victoria; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Neuropsychology; Psychology; Neuropsychological test; Cognition; Neuropsychological assessment; Logistic regression; Discriminant validity; Normative; Population; Clinical psychology; Psychometrics; Psychiatry; Medicine","score_opus":0.5986475204495445,"score_gpt":0.5290081435762019,"score_spread":0.06963937687334265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387369749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.960629,0.0010923357,0.000027667094,0.028685391,0.00005479817,0.009283642,0.000053044037,0.00002619919,0.00014791175],"genre_scores_gemma":[0.9917079,0.0009182568,0.000013175859,0.0015921735,0.00016606943,0.0055054333,0.000034171477,0.000023755996,0.00003901276],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9967071,0.00075288134,0.00021721558,0.00051852973,0.0009761192,0.00082816917],"domain_scores_gemma":[0.9878922,0.011211509,0.000036223966,0.0003031166,0.0003530163,0.00020393438],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0067685256,0.00017188051,0.0001918704,0.00043344664,0.0009816174,0.00023528158,0.00030401125,0.000059238195,0.00007466896],"category_scores_gemma":[0.001405411,0.00009327389,0.00008133151,0.0007457477,0.00047630654,0.000098264645,0.000064035754,0.00054381957,0.00005048889],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003427573,0.0012488024,0.96595895,0.000024682195,0.0003644788,0.00011890911,0.003223264,1.0697694e-7,0.00017545099,0.00009583996,0.0046169967,0.020744951],"study_design_scores_gemma":[0.0031972087,0.01334974,0.97630227,0.00008809078,0.000091087386,0.000014010683,0.004751891,0.000035744804,0.0002982569,0.0005401037,0.0012342179,0.0000973706],"about_ca_topic_score_codex":0.0036801458,"about_ca_topic_score_gemma":0.0073976335,"teacher_disagreement_score":0.03107894,"about_ca_system_score_codex":0.000059496087,"about_ca_system_score_gemma":0.00033507321,"threshold_uncertainty_score":0.7549907},"labels":[],"label_agreement":null},{"id":"W4387571366","doi":"10.1186/s13195-023-01312-8","title":"Retinal mid-peripheral capillary free zones are enlarged in cognitively unimpaired older adults at high risk for Alzheimer’s disease","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health; Warren Alpert Foundation","keywords":"Medicine; Peripheral; Retinal; Ophthalmology; Neurology; Cardiology; Internal medicine; Audiology","score_opus":0.06905064625587107,"score_gpt":0.3533751464194478,"score_spread":0.2843245001635767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387571366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94750583,0.03670667,0.000011253493,0.010821702,0.00023431436,0.0040112757,0.00033236737,0.00022333807,0.00015326854],"genre_scores_gemma":[0.9865184,0.009571055,0.0002491345,0.0005630735,0.00038399987,0.001153607,0.0007478139,0.00016839062,0.0006445204],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99468637,0.0008601349,0.00054593605,0.0009792519,0.0013496618,0.0015786334],"domain_scores_gemma":[0.99667305,0.00080260437,0.00014906573,0.00086702517,0.0007625161,0.0007457664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015261999,0.00046257692,0.0006497401,0.0006611483,0.0006020668,0.000059024926,0.00051689387,0.00025132063,0.0004986426],"category_scores_gemma":[0.00056439807,0.00037897847,0.0003524913,0.0013829577,0.0005775279,0.00015794995,0.00024803978,0.000796499,0.00017607771],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.077323616,0.0026978622,0.7044973,0.0003045213,0.0043688314,0.002445566,0.007681159,0.000008271849,0.0022079893,0.00025040898,0.12547012,0.072744355],"study_design_scores_gemma":[0.017318081,0.0014934781,0.9613777,0.00052084395,0.00034901185,0.000016741289,0.002831053,0.00057692523,0.0024049268,0.0013686155,0.011236607,0.00050604885],"about_ca_topic_score_codex":0.0017651003,"about_ca_topic_score_gemma":0.00066693063,"teacher_disagreement_score":0.25688037,"about_ca_system_score_codex":0.0000970804,"about_ca_system_score_gemma":0.00036084093,"threshold_uncertainty_score":0.9998662},"labels":[],"label_agreement":null},{"id":"W4387601785","doi":"10.1186/s13195-023-01316-4","title":"Hippocampal injections of soluble amyloid-beta oligomers alter electroencephalographic activity during wake and slow-wave sleep in rats","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Sleep & Circadian Network; Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Electroencephalography; Hippocampal formation; Hippocampus; Wakefulness; Neuroscience; Slow-wave sleep; Dentate gyrus; Amyloid beta; Sleep (system call); Medicine; Dementia; Alzheimer's disease; Psychology; Internal medicine; Disease","score_opus":0.09404748421546988,"score_gpt":0.37272990256989486,"score_spread":0.278682418354425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387601785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97845405,0.018257268,0.0000019292816,0.0011435837,0.000065975466,0.0014275025,0.000018671348,0.000095330586,0.0005356816],"genre_scores_gemma":[0.9839983,0.01528195,0.000037838327,0.000035467223,0.000092563154,0.00035662987,0.000043447588,0.0000621131,0.000091675225],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9957512,0.0005401778,0.00033483174,0.0006859905,0.0012236414,0.0014641496],"domain_scores_gemma":[0.99805003,0.00034646905,0.00006531274,0.0006228655,0.0003086548,0.00060668413],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010848782,0.00029284638,0.0005180776,0.0017326194,0.00035779158,0.00005751027,0.00018824721,0.00015037536,0.00014639016],"category_scores_gemma":[0.000056155583,0.0002503544,0.00018868779,0.003046709,0.000663569,0.00031769177,0.0001618382,0.0008469547,0.00007080796],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013399417,0.004628616,0.47970507,0.00027220865,0.04523346,0.002121929,0.003572902,0.000035653742,0.35616267,0.00027313607,0.0024064877,0.09218846],"study_design_scores_gemma":[0.0075593707,0.0023178735,0.7791314,0.00014202597,0.00026794113,0.000071686074,0.0005595021,0.00071272935,0.20758422,0.001024466,0.000252922,0.0003758434],"about_ca_topic_score_codex":0.0010935962,"about_ca_topic_score_gemma":0.0001869075,"teacher_disagreement_score":0.29942638,"about_ca_system_score_codex":0.00008815741,"about_ca_system_score_gemma":0.00036831174,"threshold_uncertainty_score":0.9999949},"labels":[],"label_agreement":null},{"id":"W4387874035","doi":"10.1186/s13195-023-01325-3","title":"Cognitive impact of multidomain intervention and omega 3 according to blood Aβ42/40 ratio: a subgroup analysis from the randomized MAPT trial","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut Universitaire de Gériatrie de Montréal","funders":"National Institute on Aging; Fondation de France; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Caisse nationale de solidarité pour l'autonomie; Fondation PremUP; Equipex","keywords":"Subgroup analysis; Randomized controlled trial; Intervention (counseling); Psychology; Cognition; Medicine; Clinical psychology; Internal medicine; Psychiatry; Meta-analysis","score_opus":0.1351789395218085,"score_gpt":0.4642693895628244,"score_spread":0.3290904500410159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387874035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863872,0.0052156765,0.0004448626,0.002925334,0.00015135565,0.004605046,0.00016308515,0.0000641047,0.000043339292],"genre_scores_gemma":[0.9968533,0.0017482813,0.00017434488,0.0001072004,0.00030809463,0.0005526628,0.00018610382,0.000042975385,0.000027056009],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99121845,0.005326029,0.00067495374,0.00056805724,0.0012550657,0.00095742126],"domain_scores_gemma":[0.9867228,0.011741485,0.00016092407,0.00049289316,0.0005205091,0.0003613376],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.010866493,0.0002453031,0.0009111304,0.0011728744,0.0005678394,0.0002720212,0.00046872703,0.00012931375,0.0002537431],"category_scores_gemma":[0.002847594,0.00015499369,0.0008073242,0.0036586178,0.00051618024,0.00024704303,0.00020182996,0.0006911467,0.00007224583],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.89213455,0.00046073965,0.005182908,0.000014467011,0.014956605,0.000015056348,0.006703749,0.000020876229,0.03224529,0.00003645016,0.0011476154,0.047081713],"study_design_scores_gemma":[0.86843526,0.006629394,0.05153951,0.00029908743,0.0018598045,0.000001976073,0.008119599,0.0054352926,0.054786082,0.0023515811,0.00009363518,0.0004487503],"about_ca_topic_score_codex":0.023925798,"about_ca_topic_score_gemma":0.0015605355,"teacher_disagreement_score":0.046632964,"about_ca_system_score_codex":0.00006157108,"about_ca_system_score_gemma":0.0001723579,"threshold_uncertainty_score":0.982574},"labels":[],"label_agreement":null},{"id":"W4389683409","doi":"10.1186/s13195-023-01356-w","title":"NeuroEPO plus (NeuralCIM®) in mild-to-moderate Alzheimer’s clinical syndrome: the ATHENEA randomized clinical trial","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Erythropoietin and Anemia Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Internal medicine; Randomized controlled trial; Montreal Cognitive Assessment; Gastroenterology; Cognitive impairment; Disease; Pathology","score_opus":0.48030524943844827,"score_gpt":0.544363344482378,"score_spread":0.06405809504392973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389683409","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9099159,0.010863539,0.0000097326165,0.0666082,0.0014771592,0.009861144,0.000010442301,0.00025670242,0.0009971429],"genre_scores_gemma":[0.9622552,0.02829131,0.00031126154,0.0044928626,0.0012579291,0.0016649985,0.00006801582,0.00016080037,0.0014976285],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.98471266,0.00860532,0.0021436592,0.0012783854,0.0017566354,0.0015033218],"domain_scores_gemma":[0.9854442,0.011609224,0.00019040173,0.0016344687,0.0003530262,0.00076870184],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.023613406,0.0004942979,0.0020814568,0.0005608222,0.00043992535,0.00015662362,0.0008016148,0.0003826635,0.0004926539],"category_scores_gemma":[0.0022802127,0.00028838657,0.0011794545,0.0020055792,0.0014442543,0.0001079338,0.00035904752,0.0023442935,0.0025399341],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.8677689,0.0018522494,0.0015545876,0.000009588462,0.0049282075,0.0027400753,0.0010550545,0.00003112469,0.00006771493,0.00021582605,0.042256452,0.07752026],"study_design_scores_gemma":[0.93099254,0.0071741934,0.009092442,0.00015612827,0.0006944454,0.00017684286,0.00041549988,0.0027288042,0.00036636423,0.00081278774,0.04689895,0.0004910018],"about_ca_topic_score_codex":0.00042947318,"about_ca_topic_score_gemma":0.00005145046,"teacher_disagreement_score":0.07702926,"about_ca_system_score_codex":0.00006332322,"about_ca_system_score_gemma":0.0008623754,"threshold_uncertainty_score":0.9999573},"labels":[],"label_agreement":null},{"id":"W4389966265","doi":"10.1186/s13195-023-01360-0","title":"Statins and cognitive decline in patients with Alzheimer’s and mixed dementia: a longitudinal registry-based cohort study","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"Medicinska Forskningsrådet; Karolinska Institutet","keywords":"Medicine; Simvastatin; Dementia; Statin; Atorvastatin; Cohort; Internal medicine; Cognitive decline; Cohort study; Rosuvastatin; Physical therapy; Gerontology; Disease","score_opus":0.09119846079507639,"score_gpt":0.3842397506228643,"score_spread":0.29304128982778793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389966265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98237145,0.011590162,0.000026179385,0.0007008219,0.000028062152,0.005123457,0.000026200025,0.00005163306,0.000082025894],"genre_scores_gemma":[0.99797064,0.00086758786,0.00016144743,0.00018666232,0.00006416965,0.00055769755,0.0001285505,0.000050276692,0.000012972257],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99615127,0.0005838501,0.00031102094,0.00068381894,0.0016085572,0.000661511],"domain_scores_gemma":[0.9983415,0.00025434952,0.000061888786,0.00049510517,0.0005334994,0.00031365306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0031823514,0.00022980165,0.0005068633,0.00040656855,0.00023763369,0.000070182,0.00010300677,0.00008220392,0.000035922825],"category_scores_gemma":[0.00010577346,0.000170217,0.000055368597,0.0009876714,0.00030940797,0.00009899491,0.000116887546,0.0005079839,0.000014241425],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025410259,0.000816544,0.9289668,0.000020150559,0.005580728,0.0001708699,0.00037064485,0.0000013432982,0.000007807428,0.0000038717735,0.0001937974,0.061326403],"study_design_scores_gemma":[0.015789723,0.004181171,0.97760946,0.00009769792,0.0006725811,0.0000047424405,0.00066105294,0.00008444421,0.00018926115,0.000020750545,0.0005168846,0.00017221173],"about_ca_topic_score_codex":0.0022897294,"about_ca_topic_score_gemma":0.00086583936,"teacher_disagreement_score":0.061154194,"about_ca_system_score_codex":0.000023124516,"about_ca_system_score_gemma":0.00031488074,"threshold_uncertainty_score":0.69412476},"labels":[],"label_agreement":null},{"id":"W4390825876","doi":"10.1186/s13195-024-01383-1","title":"Diagnostic accuracy of research criteria for prodromal frontotemporal dementia","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Western University; Occupational Cancer Research Centre; Health Sciences Centre; Montreal Neurological Institute and Hospital; University of Toronto; Sunnybrook Health Science Centre; Université Laval","funders":"NIHR Cambridge Biomedical Research Centre; Medical Research Council; Canadian Institutes of Health Research; Associazione Italiana Ricerca Alzheimer; Stockholms Läns Landsting; Familjen Erling-Perssons Stiftelse; European Commission; Hjärnfonden; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; UK Dementia Research Institute; Fondazione Cariplo; Vetenskapsrådet; Fondation pour la Recherche sur Alzheimer; Ministero della Salute; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; ZonMw; Weston Brain Institute; Alzheimer's Drug Discovery Foundation; Brain Research UK; Deutsche Forschungsgemeinschaft; Stichting Dioraphte; University of Cambridge; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; Alzheimer Nederland; EU Joint Programme – Neurodegenerative Disease Research; Stiftelsen för Gamla Tjänarinnor; Alzheimer's Association","keywords":"Frontotemporal dementia; Atrophy; Internal medicine; Medicine; Dementia; Cohort; Oncology; Psychology; Psychiatry; Disease","score_opus":0.3533920116111081,"score_gpt":0.5298283425132517,"score_spread":0.1764363309021436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390825876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82565963,0.14073461,0.00022833509,0.020169359,0.00051582785,0.010163563,0.000114210074,0.0002460845,0.0021683646],"genre_scores_gemma":[0.9892586,0.005234428,0.0015790616,0.0000742708,0.0009898199,0.001655334,0.000086837914,0.00013849072,0.000983179],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99257165,0.0011294625,0.00065279804,0.0009290107,0.0029970035,0.0017200661],"domain_scores_gemma":[0.9898258,0.0065531936,0.000045350684,0.0010164992,0.0020590147,0.0005001275],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.008439582,0.00027413561,0.0005349518,0.0010149176,0.00038700656,0.00029717438,0.000721036,0.00024184021,0.0023282606],"category_scores_gemma":[0.0029893408,0.00020575196,0.00028106698,0.0016305327,0.0010735876,0.0004216931,0.00033728225,0.0013987302,0.00031700893],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006774864,0.0017421476,0.013220642,0.0013248333,0.0074736373,0.0005569887,0.0037995644,0.0000022244492,0.3206643,0.004223422,0.27559066,0.36462674],"study_design_scores_gemma":[0.010279567,0.018076865,0.22256742,0.0035831355,0.0004760653,0.00012756804,0.00087663735,0.006248631,0.106433265,0.016677748,0.6135916,0.001061504],"about_ca_topic_score_codex":0.0010751917,"about_ca_topic_score_gemma":0.000027969705,"teacher_disagreement_score":0.36356524,"about_ca_system_score_codex":0.00015050384,"about_ca_system_score_gemma":0.0012324392,"threshold_uncertainty_score":0.99858373},"labels":[],"label_agreement":null},{"id":"W4391051416","doi":"10.1186/s13195-023-01376-6","title":"Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; National Institute of General Medical Sciences; National Cancer Institute; Helmholtz Zentrum München; National Heart, Lung, and Blood Institute; Biotechnology and Biological Sciences Research Council; School of Public Health, University of Texas Health Science Center at Houston; Stanley Center for Psychiatric Research, Broad Institute; National Institutes of Health; Dementia Centre for Research Collaboration; Neuraxpharm; Terveyden ja hyvinvoinnin laitos; Hjartavernd; National Institute on Aging; Menzies Institute for Medical Research; Medical Research Council; Servier; Centre Hospitalier Universitaire de Bordeaux; Emil Aaltosen Säätiö; Hersenstichting; U.S. Department of Health and Human Services; Signe ja Ane Gyllenbergin Säätiö; Centre for Medical Systems Biology; Novo Nordisk; University of Washington; Curtin University of Technology; National Institute of Neurological Disorders and Stroke; Deutsches Zentrum für Neurodegenerative Erkrankungen; Monash University; Centre for Cognitive Ageing and Cognitive Epidemiology; University of New South Wales; Institut National de la Santé et de la Recherche Médicale; Institute of Genetics; Agence Nationale de la Recherche; Samfundet Folkhälsan; University of Edinburgh; Erasmus Medisch Centrum; Neuroscience Research Australia; Kaiser Permanente Washington Health Research Institute; University of Oxford; National Eye Institute; Folkhälsanin Tutkimussäätiö; Fresenius Medical Care North America; McGovern Medical School; University of Texas Health Science Center at San Antonio; Juho Vainion Säätiö; Internationale Stichting Alzheimer Onderzoek; Broad Institute; Finska Läkaresällskapet; Yrjö Jahnssonin Säätiö; Directorate for Biological Sciences; School of Public Health, University of Michigan; Cilag; Université de Bordeaux; National Center for Advancing Translational Sciences; Economic and Social Research Council; Kaiser Permanente; University of Tasmania; Royal Society; Massachusetts General Hospital; National Science Foundation; National Human Genome Research Institute; University of Texas Health Science Center at Houston; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Harvard University; Engineering and Physical Sciences Research Council; European Commission; Helsingin Yliopisto; School of Medicine, Boston University; National Institute on Deafness and Other Communication Disorders; Rush University; Scottish Government; Brigham and Women's Hospital","keywords":"Expression quantitative trait loci; Genome-wide association study; Biology; dNaM; Genetic association; Dementia; Genetics; Gene; DNA methylation; Single-nucleotide polymorphism; Disease; Gene expression; Medicine; Genotype; Internal medicine","score_opus":0.1576112875415924,"score_gpt":0.41521600111220286,"score_spread":0.25760471357061043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391051416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9643163,0.034675147,0.0002953966,0.000300264,0.000021210248,0.00024771612,0.000034080116,0.000005138648,0.00010476235],"genre_scores_gemma":[0.98423445,0.014545662,0.00089473993,0.000044092965,0.00003337079,0.000040274615,0.00012335513,0.000012288225,0.00007175321],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99872696,0.0004244421,0.0002402998,0.0002590257,0.00011297706,0.00023631257],"domain_scores_gemma":[0.99933654,0.0002045891,0.000055181205,0.000199783,0.00015597825,0.000047924197],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013662928,0.00009506931,0.00016755567,0.00013482002,0.00012805701,0.000024683055,0.000101341466,0.00014243233,0.000006792936],"category_scores_gemma":[0.00014187767,0.000084559644,0.000038102877,0.00023680848,0.00017769686,0.00001055766,0.00009310304,0.0001899133,0.0000019465274],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008455905,0.00008949419,0.11535714,0.000012928308,0.0007104008,8.763026e-7,0.0013030675,0.00033817565,0.8484641,0.000044428874,0.00015187595,0.033442993],"study_design_scores_gemma":[0.00042284754,0.00023105499,0.94025725,0.000009045673,0.000016727548,0.000001713981,0.00023321129,0.0037777594,0.053589143,0.0002502039,0.0011095512,0.000101483405],"about_ca_topic_score_codex":0.00027865343,"about_ca_topic_score_gemma":0.000109463275,"teacher_disagreement_score":0.8249001,"about_ca_system_score_codex":0.000022209215,"about_ca_system_score_gemma":0.00011888153,"threshold_uncertainty_score":0.34482422},"labels":[],"label_agreement":null},{"id":"W4391260553","doi":"10.1186/s13195-024-01386-y","title":"Mild behavioral impairment in early Alzheimer’s disease and its association with APOE and BDNF risk genetic polymorphisms","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; Ministerstvo Zdravotnictví Ceské Republiky; Grantová Agentura České Republiky; European Commission","keywords":"Apathy; Apolipoprotein E; Psychology; Anxiety; Clinical psychology; Alzheimer's disease; Depression (economics); Neuropsychology; Disease; Psychiatry; Oncology; Internal medicine; Medicine; Cognition","score_opus":0.11851093307448474,"score_gpt":0.3782120478804788,"score_spread":0.25970111480599406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391260553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9399937,0.05717486,0.000005728401,0.0016075706,0.00012630437,0.0009508341,0.000051159772,0.000058137386,0.000031697793],"genre_scores_gemma":[0.99163216,0.0076153064,0.00005078529,0.00011450983,0.00014538015,0.00019539586,0.000005572989,0.000040907653,0.00019996516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969034,0.0007933414,0.00022660184,0.00068070664,0.0008434771,0.0005524456],"domain_scores_gemma":[0.99909043,0.0002865966,0.000051500872,0.00022813624,0.00007131945,0.00027202978],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008322552,0.00020064623,0.00016339206,0.00032639905,0.00032995845,0.00038393144,0.00016829853,0.000097145945,0.000048416616],"category_scores_gemma":[0.000035267258,0.00015122305,0.000041556083,0.0005979219,0.00016061755,0.00041188145,0.000074378324,0.00051794824,0.000036789395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003300591,0.0015687419,0.23883218,0.00003980839,0.0008184776,0.000998834,0.008007126,0.00011244657,0.5362724,0.0022877331,0.0023627537,0.20539889],"study_design_scores_gemma":[0.0025353576,0.0032849414,0.45533255,0.00014750104,0.0003459559,0.000026429901,0.000078410034,0.005438332,0.52791387,0.0014180985,0.002759786,0.00071879005],"about_ca_topic_score_codex":0.0004434137,"about_ca_topic_score_gemma":0.000074223826,"teacher_disagreement_score":0.21650037,"about_ca_system_score_codex":0.000057360623,"about_ca_system_score_gemma":0.00014061811,"threshold_uncertainty_score":0.61666965},"labels":[],"label_agreement":null},{"id":"W4391509762","doi":"10.1186/s13195-023-01370-y","title":"Anodal HD-tDCS on the dominant anterior temporal lobe and dorsolateral prefrontal cortex: clinical results in patients with mild cognitive impairment","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Transcranial Magnetic Stimulation Studies","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Transcranial direct-current stimulation; Montreal Cognitive Assessment; Dorsolateral prefrontal cortex; Neuromodulation; Neurocognitive; Brain stimulation; Psychology; Cognition; Stimulation; Audiology; Prefrontal cortex; Medicine; Physical medicine and rehabilitation; Internal medicine; Cognitive impairment; Neuroscience","score_opus":0.14320644539438934,"score_gpt":0.40618727725797077,"score_spread":0.26298083186358145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391509762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993762,0.0013409326,0.0000068034064,0.0020169101,0.00023473683,0.0021703935,0.00014066516,0.000042683798,0.0002848757],"genre_scores_gemma":[0.9985279,0.0006234293,0.000029314615,0.00047690724,0.00009006222,0.00012905593,0.0000060453376,0.00003595258,0.00008133761],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9960162,0.0010190954,0.0005312292,0.00083807175,0.0010126518,0.00058272673],"domain_scores_gemma":[0.9968752,0.0025304165,0.000055039505,0.00028315317,0.00012829751,0.0001278654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013615902,0.00025217878,0.00030775156,0.00020630712,0.0002911683,0.00021625796,0.00026092798,0.00007993348,0.000059150723],"category_scores_gemma":[0.00018076652,0.00013983755,0.000074477786,0.0005293052,0.0009207451,0.00018387497,0.000110664296,0.000673793,0.000061000836],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.24378839,0.007844428,0.43305162,0.000075623226,0.0017370582,0.0011232446,0.03233505,0.000016812268,0.030929593,0.000650161,0.0045688967,0.24387912],"study_design_scores_gemma":[0.008451314,0.007813487,0.9800754,0.00027624186,0.000024548357,0.0000038031856,0.00017863537,0.0004848393,0.0014004251,0.0001082348,0.0009685975,0.0002144625],"about_ca_topic_score_codex":0.00021013737,"about_ca_topic_score_gemma":0.0000950911,"teacher_disagreement_score":0.5470238,"about_ca_system_score_codex":0.000032236916,"about_ca_system_score_gemma":0.00010216337,"threshold_uncertainty_score":0.5702409},"labels":[],"label_agreement":null},{"id":"W4391648738","doi":"10.1186/s13195-024-01390-2","title":"DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute on Aging","keywords":"Inflammation; Neurology; Disease; Geriatric psychiatry; Apoptosis; Amyloid (mycology); Medicine; Cancer research; Biology; Neuroscience; Bioinformatics; Internal medicine; Genetics; Pathology; Psychiatry","score_opus":0.04394735293660781,"score_gpt":0.3345130181060906,"score_spread":0.2905656651694828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391648738","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8838225,0.114068955,0.00005744017,0.001107229,0.000051743686,0.0006709145,0.0000072904627,0.00001263944,0.00020130265],"genre_scores_gemma":[0.992606,0.0068284487,0.000060619997,0.000019714056,0.00010985174,0.00016070095,0.00015560864,0.000027153303,0.000031915093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841166,0.0004111196,0.00025463142,0.00032608025,0.0003181115,0.00027839796],"domain_scores_gemma":[0.9992638,0.00010470967,0.000043693406,0.0003282138,0.00020050896,0.000059024933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00093684497,0.00014122733,0.00011070912,0.00018792038,0.00014255874,0.00009077419,0.00017258972,0.0001108215,0.000025752159],"category_scores_gemma":[0.00009576619,0.00010111318,0.000051059294,0.00042913627,0.00015935856,0.00003747138,0.00009210524,0.00020420397,0.0000071046798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033386468,0.000041549498,0.0007008817,0.000017561042,0.0001426405,0.000002976213,0.0007201252,0.000035716756,0.92190313,0.00007941741,0.00023448726,0.07578765],"study_design_scores_gemma":[0.00040582253,0.00025797097,0.0056611067,0.00007990862,0.000030201045,0.0000021805326,0.00022516791,0.00066364626,0.98846996,0.00054755964,0.0035238683,0.00013262931],"about_ca_topic_score_codex":0.00015751272,"about_ca_topic_score_gemma":0.00010221249,"teacher_disagreement_score":0.1087835,"about_ca_system_score_codex":0.000007907615,"about_ca_system_score_gemma":0.00012941232,"threshold_uncertainty_score":0.4123276},"labels":[],"label_agreement":null},{"id":"W4391785746","doi":"10.1186/s13195-024-01404-z","title":"Correction: Is later‑life depression a risk factor for Alzheimer’s disease or a prodromal symptom: a study using post‑mortem human brain tissue?","year":2024,"lang":"en","type":"erratum","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Depression (economics); Late life depression; Disease; Medicine; Risk factor; Human brain; Brain tissue; Alzheimer's disease; Psychology; Internal medicine; Psychiatry; Cognition","score_opus":0.1630583085994622,"score_gpt":0.4771366681583195,"score_spread":0.3140783595588573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391785746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6083401,0.2488313,0.00010656303,0.009596183,0.029077582,0.08876188,0.005652969,0.001452959,0.008180489],"genre_scores_gemma":[0.7281511,0.0030799895,0.00011219467,0.0013203836,0.0076136594,0.006342537,0.0014340625,0.0009679697,0.2509781],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9877456,0.0017936983,0.0011215162,0.002620853,0.00442888,0.0022894512],"domain_scores_gemma":[0.99284136,0.0008796051,0.00032252783,0.0017078101,0.002461374,0.0017873306],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0027725354,0.001176314,0.0014756382,0.0018623515,0.0015154468,0.0008511998,0.0009341092,0.0006951541,0.005587764],"category_scores_gemma":[0.0008203928,0.0008508355,0.00069984526,0.0015311589,0.00049392163,0.00035982672,0.00068229844,0.0043580467,0.00037771612],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013345298,0.004229025,0.018575475,0.00042820882,0.018762512,0.0012794308,0.0040013636,2.5180165e-7,0.0020573135,0.0000027814826,0.8535547,0.08376361],"study_design_scores_gemma":[0.017586688,0.03660379,0.18129714,0.0044900007,0.011124438,0.00018524643,0.0042661666,0.0024722998,0.0041553234,0.0002312597,0.73487437,0.0027132854],"about_ca_topic_score_codex":0.0011043759,"about_ca_topic_score_gemma":0.00020813593,"teacher_disagreement_score":0.2457513,"about_ca_system_score_codex":0.00027261037,"about_ca_system_score_gemma":0.004878787,"threshold_uncertainty_score":0.99978447},"labels":[],"label_agreement":null},{"id":"W4391841703","doi":"10.1186/s13195-024-01399-7","title":"Relationships of change in Clinical Dementia Rating (CDR) on patient outcomes and probability of progression: observational analysis","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"Genentech; Sage Therapeutics; National Institutes of Health; H. Lundbeck A/S; Prothena; National Institute on Aging; Alzheimer's Association; Consortium canadien en neurodégénérescence associée au vieillissement; Alzheimer's Drug Discovery Foundation; Canadian Institutes of Health Research; Weston Brain Institute; Eli Lilly and Company; National Institute of General Medical Sciences; Novo Nordisk; Eisai","keywords":"Observational study; Geriatric psychiatry; Dementia; Neurology; Medicine; Clinical Dementia Rating; Psychiatry; Psychology; Clinical psychology; Internal medicine","score_opus":0.5419824993353203,"score_gpt":0.5387984115212058,"score_spread":0.0031840878141145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391841703","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98551226,0.008910305,0.000016362737,0.0035737217,0.000031505115,0.0016265023,0.000011437558,0.000013943224,0.0003039385],"genre_scores_gemma":[0.9981644,0.00066377234,0.00068953354,0.00008037759,0.000031405732,0.00029685465,0.000042961827,0.000011678734,0.000018984341],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.996331,0.0010851717,0.0006950587,0.00038084533,0.0012215617,0.0002863664],"domain_scores_gemma":[0.9975171,0.0015226374,0.00007546332,0.00027175507,0.00049189245,0.00012114267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0053421524,0.000109919834,0.00037292816,0.00066035584,0.000072042014,0.000027412081,0.000091230315,0.0000863021,0.0002818702],"category_scores_gemma":[0.00054519734,0.00007660604,0.0001687709,0.0015575934,0.0003157785,0.00013427004,0.000086062595,0.00059614173,0.0000053012122],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052724814,0.0007694036,0.836409,0.0000535425,0.00231731,0.000008870367,0.0008862621,8.255653e-7,0.00022419788,0.00047605843,0.00004848577,0.1582788],"study_design_scores_gemma":[0.0008726425,0.0016675842,0.99316746,0.00020120587,0.00023005775,5.968065e-7,0.0001896319,0.0010283882,0.0015718256,0.00065552985,0.00035620012,0.000058895614],"about_ca_topic_score_codex":0.00010234785,"about_ca_topic_score_gemma":0.000045092827,"teacher_disagreement_score":0.1582199,"about_ca_system_score_codex":0.000022911314,"about_ca_system_score_gemma":0.00019584128,"threshold_uncertainty_score":0.3123904},"labels":[],"label_agreement":null},{"id":"W4392200056","doi":"10.1186/s13195-024-01415-w","title":"Machine learning prediction of future amyloid beta positivity in amyloid-negative individuals","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; F. Hoffmann-La Roche; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Pfizer; National Institute on Aging; Alzheimer's Association","keywords":"Algorithm; Artificial intelligence; Machine learning; Mathematics; Computer science","score_opus":0.06780893515594853,"score_gpt":0.38513736169726376,"score_spread":0.3173284265413152,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392200056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94057345,0.044172935,0.000046613426,0.0044753845,0.0001625941,0.0019242256,0.0001234135,0.000117346586,0.008404036],"genre_scores_gemma":[0.9889645,0.009125644,0.00013209193,0.000093036215,0.0003747951,0.00019480559,0.00015086988,0.0000535856,0.0009106547],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9952754,0.0011743462,0.0004065907,0.00057879667,0.0017974507,0.0007674653],"domain_scores_gemma":[0.9982784,0.00066074496,0.000045861878,0.00030434498,0.0004810813,0.00022958175],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0037446124,0.00023153411,0.00040314122,0.001132417,0.0001710549,0.00010937784,0.00022314051,0.00016729128,0.0011905967],"category_scores_gemma":[0.000118975135,0.00018355498,0.00016464654,0.0017584463,0.00035903856,0.00032762875,0.0001470906,0.001817549,0.000104377774],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015254281,0.0012201908,0.5480921,0.00017528443,0.0030192537,0.0002420592,0.0050287517,0.0000085463,0.06541763,0.0009465548,0.0015081324,0.37281603],"study_design_scores_gemma":[0.004256301,0.0048747244,0.7989026,0.0005776306,0.00016072927,0.00004713135,0.0016651042,0.0017212221,0.14542238,0.0011456254,0.04097459,0.00025197314],"about_ca_topic_score_codex":0.0006179563,"about_ca_topic_score_gemma":0.000040395058,"teacher_disagreement_score":0.37256405,"about_ca_system_score_codex":0.0000979671,"about_ca_system_score_gemma":0.00039391132,"threshold_uncertainty_score":0.9997224},"labels":[],"label_agreement":null},{"id":"W4393856466","doi":"10.1186/s13195-024-01434-7","title":"Cerebrospinal fluid amyloid-β and cerebral microbleed are associated with distinct neuropsychiatric sub-syndromes in cognitively impaired patients","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Intracerebral and Subarachnoid Hemorrhage Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; University of California, San Diego; National Institutes of Health; H. Lundbeck A/S; Servier; Eisai; Genentech; IXICO; National Natural Science Foundation of China; Pfizer; Novartis Pharmaceuticals Corporation; Northern California Institute for Research and Education; China Postdoctoral Science Foundation; F. Hoffmann-La Roche; University of Southern California; Medical Science and Technology Project of Zhejiang Province; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; National Institute on Aging; Alzheimer's Association; U.S. Department of Defense","keywords":"Neurology; Geriatric psychiatry; Cerebrospinal fluid; Neuroscience; Behavioral neurology; Medicine; Dementia; Amyloid (mycology); Pathology; Psychology; Psychiatry; Disease","score_opus":0.06319353020491524,"score_gpt":0.33203266360320527,"score_spread":0.26883913339829,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393856466","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9795498,0.01495478,0.000005663965,0.0029050454,0.00010299989,0.0018013713,0.000090527305,0.00014999864,0.0004398108],"genre_scores_gemma":[0.9980444,0.0008040655,0.00009626449,0.00017321734,0.00016601557,0.0001584034,0.00015081729,0.00011854516,0.00028832752],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99524236,0.0006504072,0.00044469198,0.0009200782,0.0013953982,0.0013470387],"domain_scores_gemma":[0.99800044,0.0004370286,0.00005965129,0.00034844654,0.00071625604,0.00043815354],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012327072,0.0004017211,0.0005819803,0.0009845648,0.00033583786,0.0002880411,0.00025982276,0.00021655875,0.00022383712],"category_scores_gemma":[0.0002125392,0.0002873645,0.00012920798,0.0022905131,0.00048242352,0.00030201074,0.00013661373,0.0015941083,0.00012528416],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047102333,0.0019371168,0.8300816,0.00027945248,0.0015153785,0.0017950678,0.0011289215,7.917547e-7,0.0077266097,0.000085600695,0.0038352145,0.14690405],"study_design_scores_gemma":[0.00570882,0.0037070243,0.9838378,0.0005456141,0.00010167799,0.00012212872,0.0003083025,0.002496452,0.0022412983,0.00019843542,0.0003383033,0.00039414992],"about_ca_topic_score_codex":0.00031730422,"about_ca_topic_score_gemma":0.000115138355,"teacher_disagreement_score":0.15375623,"about_ca_system_score_codex":0.00016215749,"about_ca_system_score_gemma":0.0004772404,"threshold_uncertainty_score":0.99995786},"labels":[],"label_agreement":null},{"id":"W4394720570","doi":"10.1186/s13195-024-01449-0","title":"Biophysical models applied to dementia patients reveal links between geographical origin, gender, disease duration, and loss of neural inhibition","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias; Fondo de Fomento al Desarrollo Científico y Tecnológico; Fondo para la Investigación Científica y Tecnológica; National Institute on Aging; National Institutes of Health; Agencia Nacional de Investigación y Desarrollo; Consejo Nacional de Investigaciones Científicas y Técnicas; Alzheimer's Society; Global Brain Health Institute; Alzheimer's Association","keywords":"Dementia; Frontotemporal dementia; Neuroscience; Neurology; Disease; Functional magnetic resonance imaging; Medicine; Inhibitory postsynaptic potential; Population; Psychology; Neurodegeneration; Internal medicine","score_opus":0.1655997738634177,"score_gpt":0.36870777818694805,"score_spread":0.20310800432353035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394720570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912702,0.001293343,0.0003750844,0.005638129,0.00012974697,0.0009783885,0.00011500617,0.00008223676,0.00011788604],"genre_scores_gemma":[0.9984751,0.00027944447,0.00006775259,0.0006926355,0.00023343717,0.00018514371,0.000024473833,0.000031739623,0.000010298691],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9970472,0.0003167421,0.0003179333,0.0007770145,0.0011089814,0.00043213123],"domain_scores_gemma":[0.9972194,0.0019669614,0.000035601744,0.0002778567,0.00023352753,0.00026668198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005416297,0.00018548146,0.00020888001,0.00037473495,0.00033406253,0.00013309481,0.00017387392,0.0000870273,0.00001902842],"category_scores_gemma":[0.00035638438,0.00015937771,0.00008248668,0.0010239059,0.0004576939,0.00033791442,0.00020954083,0.00052279537,0.00002881075],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006322845,0.0031933864,0.12660484,0.00045122663,0.0037062117,0.00019076047,0.007937088,0.0010080715,0.54011834,0.12373822,0.0427955,0.14393349],"study_design_scores_gemma":[0.0055644484,0.0034858584,0.51591337,0.00021853465,0.00052695896,0.000008159208,0.00022235836,0.016522378,0.24513222,0.19477136,0.01574072,0.0018936459],"about_ca_topic_score_codex":0.00003320732,"about_ca_topic_score_gemma":0.0000024406115,"teacher_disagreement_score":0.3893085,"about_ca_system_score_codex":0.000021616219,"about_ca_system_score_gemma":0.00007837552,"threshold_uncertainty_score":0.64992344},"labels":[],"label_agreement":null},{"id":"W4394785048","doi":"10.1186/s13195-024-01440-9","title":"Synaptic vesicle glycoprotein 2 A in serum is an ideal biomarker for early diagnosis of Alzheimer’s disease","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Education and Child Care","funders":"Capital Medical University; National Natural Science Foundation of China","keywords":"Biomarker; Geriatric psychiatry; Neurology; Disease; Medicine; Glycoprotein; Neuroscience; Internal medicine; Psychology; Biology; Psychiatry; Biochemistry","score_opus":0.16146325730542904,"score_gpt":0.43058900251023635,"score_spread":0.2691257452048073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394785048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.70740324,0.28358817,0.000010817816,0.0038424893,0.00008077847,0.0044061737,0.00040275534,0.00010698279,0.0001586152],"genre_scores_gemma":[0.990912,0.0047319797,0.00030431585,0.00020266729,0.000173871,0.0033603283,0.00012165134,0.0001554905,0.00003770167],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99472946,0.00051837,0.00062497327,0.0010600104,0.0016264135,0.0014407971],"domain_scores_gemma":[0.996418,0.00061699084,0.000059467548,0.0010615671,0.00051133835,0.0013326177],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001587269,0.00041283385,0.0006186863,0.0010801201,0.00020216696,0.0001706808,0.00041739352,0.0001816492,0.00082698796],"category_scores_gemma":[0.00012680102,0.00033516335,0.00041871963,0.0015088954,0.00054097275,0.0005456949,0.00012882908,0.0005307706,0.00022766835],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02758001,0.009989349,0.22655357,0.00068191113,0.13205709,0.0040624407,0.0038117145,0.000005832209,0.004085627,0.0017644699,0.014798061,0.57460994],"study_design_scores_gemma":[0.02126164,0.01526257,0.8276166,0.002386199,0.0046232627,0.000038583577,0.0007819833,0.010823256,0.08733519,0.014352662,0.0139109455,0.0016071228],"about_ca_topic_score_codex":0.001580749,"about_ca_topic_score_gemma":0.00003742128,"teacher_disagreement_score":0.601063,"about_ca_system_score_codex":0.00011000551,"about_ca_system_score_gemma":0.0012601907,"threshold_uncertainty_score":0.99991006},"labels":[],"label_agreement":null},{"id":"W4396587126","doi":"10.1186/s13195-024-01438-3","title":"Irregular word reading as a marker of semantic decline in Alzheimer’s disease: implications for premorbid intellectual ability measurement","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Université de Montréal; McGill University; Douglas Mental Health University Institute; Université du Québec à Montréal","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; BioClinica; Aix-Marseille Université; F. Hoffmann-La Roche; Agence Nationale de la Recherche; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Pfizer; National Institute on Aging; Alzheimer's Association","keywords":"Reading (process); Dementia; Psychology; Semantic dementia; Cognition; Semantic memory; Disease; Cognitive decline; Word (group theory); Alzheimer's disease; Neurology; Cognitive psychology; Cognitive reserve; Medicine; Linguistics; Psychiatry; Pathology; Frontotemporal dementia","score_opus":0.19174218972977017,"score_gpt":0.44973977433070045,"score_spread":0.25799758460093025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396587126","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8155785,0.14131516,0.0014947765,0.0287099,0.00018132724,0.01029327,0.00007149103,0.00015275144,0.0022028023],"genre_scores_gemma":[0.9940971,0.003335944,0.0003262692,0.00019610628,0.00014060126,0.0015346778,0.000067330875,0.000069351016,0.00023259003],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9954836,0.0005567444,0.0006158234,0.0007945034,0.0016361565,0.000913215],"domain_scores_gemma":[0.9960411,0.0013339403,0.000042578897,0.00076574774,0.0013903934,0.0004262114],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.006441415,0.00025555037,0.0004249153,0.00082285027,0.00015969132,0.00011033414,0.00036878765,0.000097804834,0.00095947215],"category_scores_gemma":[0.0012674119,0.00021097012,0.00028416555,0.0014184697,0.00043171732,0.00017488723,0.0001885194,0.0005490713,0.00009068312],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010268091,0.0030386301,0.08384438,0.000507282,0.0056893136,0.00007059492,0.0017672064,0.0000031696065,0.11031142,0.0016785936,0.0126044005,0.77021694],"study_design_scores_gemma":[0.0050609843,0.002848141,0.82972723,0.0014829428,0.0009278037,0.000033557433,0.0006245035,0.0027017219,0.049317364,0.019074181,0.08766522,0.00053633907],"about_ca_topic_score_codex":0.00024186645,"about_ca_topic_score_gemma":0.00005112633,"teacher_disagreement_score":0.76968056,"about_ca_system_score_codex":0.00016591504,"about_ca_system_score_gemma":0.0012918363,"threshold_uncertainty_score":0.9999538},"labels":[],"label_agreement":null},{"id":"W4396809866","doi":"10.1186/s13195-024-01463-2","title":"Cerebrospinal fluid α-synuclein adds the risk of cognitive decline and is associated with tau pathology among non-demented older adults","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; National Key Scientific Instrument and Equipment Development Projects of China; Servier; Eisai; Genentech; IXICO; National Natural Science Foundation of China; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; University of California, San Diego; BioClinica; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; National Institute on Aging; Alzheimer's Association","keywords":"Cognitive decline; Dementia; Neurology; Cerebrospinal fluid; Internal medicine; Cognition; Oncology; Proportional hazards model; Mediation; Psychology; Medicine; Neuroimaging; Tauopathy; Disease; Neuroscience; Neurodegeneration","score_opus":0.03786569300209692,"score_gpt":0.3475914068527205,"score_spread":0.3097257138506236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396809866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97240967,0.024646627,0.00004926373,0.0008414895,0.000048154543,0.0014956451,0.00025587142,0.00004556389,0.00020769541],"genre_scores_gemma":[0.99418724,0.004803673,0.00005170393,0.00035505777,0.00006376223,0.00024577603,0.000105002706,0.000059012946,0.0001287848],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99746585,0.0004317385,0.00025702192,0.00054307724,0.00078365137,0.0005186704],"domain_scores_gemma":[0.99831444,0.0005522217,0.00007990231,0.00032152588,0.00050836394,0.00022353164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009646024,0.00024301026,0.00037418617,0.00021006196,0.00023740798,0.000054888922,0.00014091884,0.00012972324,0.000485838],"category_scores_gemma":[0.00012465895,0.00013735706,0.0001149776,0.0005870577,0.0005432736,0.000097983066,0.00009991683,0.00049437064,0.000032603857],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014772152,0.0038333212,0.49497765,0.00010486988,0.037469752,0.0026345626,0.014981156,5.334404e-7,0.004318443,0.00018411802,0.004527285,0.42219615],"study_design_scores_gemma":[0.008174858,0.0039039066,0.9685441,0.0010396114,0.0011322346,0.000029657187,0.0012380382,0.00094447203,0.013795435,0.00022617345,0.0007996931,0.00017181248],"about_ca_topic_score_codex":0.00060266705,"about_ca_topic_score_gemma":0.0001239766,"teacher_disagreement_score":0.47356647,"about_ca_system_score_codex":0.00003425307,"about_ca_system_score_gemma":0.00020137304,"threshold_uncertainty_score":0.5601258},"labels":[],"label_agreement":null},{"id":"W4399443274","doi":"10.1186/s13195-024-01482-z","title":"Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer’s disease: a randomized, controlled clinical trial","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Cleveland Clinic Foundation; National Institute on Aging; Arthur M. Blank Family Foundation; Alzheimer's Drug Discovery Foundation; Milken Family Foundation; Greater Houston Community Foundation","keywords":"Clinical Dementia Rating; Dementia; Clinical Global Impression; Randomized controlled trial; Medicine; Montreal Cognitive Assessment; Geriatric psychiatry; Clinical trial; Internal medicine; Disease; Psychology; Physical therapy; Psychiatry; Pathology","score_opus":0.12973295588769956,"score_gpt":0.47270137329491757,"score_spread":0.342968417407218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399443274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87815064,0.06425831,0.000059642236,0.01384922,0.00054088334,0.04260637,0.000040003328,0.00006857323,0.00042637726],"genre_scores_gemma":[0.9829667,0.005596676,0.00004882074,0.0014245292,0.00060309283,0.0089374855,0.000025137275,0.00007711999,0.00032043317],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.988863,0.005423202,0.0011595383,0.00080717297,0.002821313,0.00092575746],"domain_scores_gemma":[0.976263,0.019327132,0.00022428697,0.0005272971,0.0029883375,0.00066998025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.011518113,0.00042055474,0.001999764,0.0007826129,0.0001979726,0.00012233069,0.00041710935,0.00015867046,0.00063188456],"category_scores_gemma":[0.0056632166,0.00020192066,0.000982571,0.0010394383,0.0012248511,0.00008034814,0.00027510987,0.00094782066,0.00012572948],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.8942714,0.0026344568,0.0005982057,0.00013059075,0.020742677,0.00039506282,0.0010390064,7.765221e-8,0.0006206098,0.00025181443,0.00352486,0.07579128],"study_design_scores_gemma":[0.8746352,0.048387155,0.015013842,0.004440987,0.0058608847,0.000009034968,0.0008387992,0.0001946436,0.048535496,0.0002315137,0.001532207,0.0003202],"about_ca_topic_score_codex":0.000088507055,"about_ca_topic_score_gemma":0.000009453539,"teacher_disagreement_score":0.10481608,"about_ca_system_score_codex":0.00002411056,"about_ca_system_score_gemma":0.0009553764,"threshold_uncertainty_score":0.82340854},"labels":[],"label_agreement":null},{"id":"W4399464817","doi":"10.1186/s13195-024-01486-9","title":"Central autonomic network dysfunction and plasma Alzheimer’s disease biomarkers in older adults","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Apolipoprotein E; Neuroscience; Psychology; Internal medicine; Dementia; Alzheimer's disease; Biomarker; Disease; Medicine; Oncology; Biology","score_opus":0.09054106661268058,"score_gpt":0.34352038599149803,"score_spread":0.25297931937881746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399464817","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8767427,0.09615043,0.000039464594,0.021131124,0.0022015665,0.0022053402,0.00004558156,0.00036767742,0.0011160714],"genre_scores_gemma":[0.9942288,0.004026284,0.00003709635,0.00081985985,0.0004480597,0.00029241625,0.0000073254478,0.000060625553,0.00007956187],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9960792,0.000704202,0.0002764641,0.0011788543,0.0006916677,0.0010696341],"domain_scores_gemma":[0.99410164,0.0051230565,0.000029749748,0.00037616532,0.00006187802,0.00030750796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010476495,0.0002758159,0.00022384588,0.0004248528,0.00043360135,0.00028683105,0.00027211566,0.00009071524,0.00019904124],"category_scores_gemma":[0.0006992317,0.00024477098,0.00009791161,0.0011600951,0.00052745704,0.00051187084,0.00019328654,0.00059053383,0.00012663392],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012483274,0.0010028814,0.032506928,0.000094248986,0.0031161269,0.0009794311,0.005158736,0.0013546774,0.012713165,0.0104197785,0.16505241,0.7551183],"study_design_scores_gemma":[0.0073999707,0.0012511149,0.5927293,0.0008930699,0.00022474967,0.0000692661,0.00075972907,0.13882147,0.01825639,0.0092387665,0.22859915,0.0017570312],"about_ca_topic_score_codex":0.00024566127,"about_ca_topic_score_gemma":0.00012273133,"teacher_disagreement_score":0.7533613,"about_ca_system_score_codex":0.00010780718,"about_ca_system_score_gemma":0.00026855117,"threshold_uncertainty_score":0.9981471},"labels":[],"label_agreement":null},{"id":"W4399918304","doi":"10.1186/s13195-024-01499-4","title":"Adherence to a lifestyle intervention – just a question of self-efficacy? Analysis of the AgeWell.de-intervention against cognitive decline","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Universität Leipzig; Bundesministerium für Bildung und Forschung","keywords":"Medicine; Psychosocial; Intervention (counseling); Cognition; Randomized controlled trial; Dementia; Physical therapy; Montreal Cognitive Assessment; Cognitive decline; Clinical psychology; Gerontology; Psychiatry; Internal medicine; Cognitive impairment; Disease","score_opus":0.09065464768679093,"score_gpt":0.4617601156989713,"score_spread":0.37110546801218036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399918304","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98739934,0.006650421,0.0019109302,0.0010176436,0.00010006703,0.001786318,0.000042561976,0.00005879164,0.0010339526],"genre_scores_gemma":[0.99738675,0.0012621444,0.00012849187,0.00013302437,0.00008007377,0.00021999022,0.00008063105,0.000029169374,0.0006797229],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9958306,0.0012738667,0.0005810041,0.0004458738,0.0013888777,0.0004797695],"domain_scores_gemma":[0.9974207,0.0005928848,0.000103879516,0.00038935625,0.0012912577,0.00020187057],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0045261276,0.00017245162,0.00039720506,0.0011698176,0.00010469584,0.00007976032,0.00032260714,0.00009820976,0.0006585944],"category_scores_gemma":[0.0005022021,0.00012233267,0.0007194269,0.0037741864,0.00024057471,0.00013951471,0.00023800244,0.00050587,0.000062692925],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029705353,0.006606355,0.10032674,0.0004170262,0.02382789,0.00006027597,0.004309658,0.000025429035,0.04058186,0.00039846153,0.0009266094,0.81954914],"study_design_scores_gemma":[0.0036792385,0.006645933,0.8139238,0.0030518314,0.0037026983,0.000008478744,0.0017920727,0.006506027,0.1577632,0.00018052103,0.0025278404,0.00021841102],"about_ca_topic_score_codex":0.000705167,"about_ca_topic_score_gemma":0.0001500292,"teacher_disagreement_score":0.81933075,"about_ca_system_score_codex":0.000088729,"about_ca_system_score_gemma":0.00025649116,"threshold_uncertainty_score":0.7211147},"labels":[],"label_agreement":null},{"id":"W4400063486","doi":"10.1186/s13195-024-01506-8","title":"The longitudinal trajectory of CSF sTREM2: the alzheimer’s disease neuroimaging initiative","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, San Francisco; University of California, Davis; Jewish General Hospital; University of California, Los Angeles; Karolinska Institutet; Sun Yat-sen University; University of South Florida; Ohio State University; Rush University; USF Health Byrd Alzheimer's Institute; McGill University; University of Rochester; Northwestern University; York University; Dartmouth College; Wake Forest University; University of California, Irvine; Georgetown University; University of Pittsburgh; Johns Hopkins University; Medical Center, University of Rochester; Case Western Reserve University; Brigham and Women's Hospital; Emory University; Cleveland Clinic; University of Pennsylvania; Yale University","keywords":"Cerebrospinal fluid; Biomarker; Medicine; Alzheimer's Disease Neuroimaging Initiative; Neurology; Internal medicine; Neuroimaging; Apolipoprotein E; Oncology; Alzheimer's disease; Disease; Psychiatry; Biology; Genetics","score_opus":0.32652464012083043,"score_gpt":0.4180790957453333,"score_spread":0.09155445562450287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400063486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.72950584,0.12887938,0.0009959327,0.111475304,0.0061002043,0.008220277,0.0002775217,0.0013446439,0.013200893],"genre_scores_gemma":[0.9929158,0.005198524,0.000016512742,0.0011460994,0.0002765799,0.00016283535,0.0000032068697,0.00006512507,0.00021529356],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99463916,0.0021102307,0.0004271734,0.00070375466,0.0014925732,0.00062708656],"domain_scores_gemma":[0.995018,0.0036168445,0.00008589029,0.00083392835,0.00023822917,0.0002071118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015238207,0.00024673512,0.00016599319,0.00024469165,0.0012454177,0.0006435601,0.0010125102,0.000037489768,0.00022703761],"category_scores_gemma":[0.0005096175,0.00014131004,0.00018605117,0.0011388998,0.0008787503,0.00047544588,0.00016439636,0.0008539187,0.00019597555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059625955,0.00018196233,0.000093375646,0.000014841034,0.00025093864,0.00032159057,0.002239916,0.00017804465,0.76563936,0.111159064,0.013099173,0.106225476],"study_design_scores_gemma":[0.00037065864,0.00024743943,0.0014153443,0.000031838965,0.00006298686,0.000023124476,0.00018287242,0.0074284337,0.9165801,0.0061560194,0.06727288,0.00022831229],"about_ca_topic_score_codex":0.000013253129,"about_ca_topic_score_gemma":0.00000922678,"teacher_disagreement_score":0.26340997,"about_ca_system_score_codex":0.00001586965,"about_ca_system_score_gemma":0.00039836488,"threshold_uncertainty_score":0.95788723},"labels":[],"label_agreement":null},{"id":"W4400298214","doi":"10.1186/s13195-024-01520-w","title":"Choroid plexus volume as a novel candidate neuroimaging marker of the Alzheimer’s continuum","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Choroid plexus; Neuroimaging; Neurology; Medicine; Neurochemistry; Neuroscience; Neurosurgery; Alzheimer's disease; Predictive value; Disease; Pathology; Psychology; Internal medicine; Radiology; Central nervous system","score_opus":0.09425279990027306,"score_gpt":0.40804592270120543,"score_spread":0.31379312280093236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400298214","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86099625,0.08984979,0.00006247453,0.015988069,0.0005928845,0.0034089766,0.000058475536,0.00015548519,0.028887572],"genre_scores_gemma":[0.9898415,0.0018948034,0.00007609519,0.00073082274,0.0002997459,0.00022727305,0.000022801683,0.00009759028,0.0068093208],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99501497,0.0005164919,0.00044889832,0.0007033954,0.0021811323,0.0011350943],"domain_scores_gemma":[0.9975887,0.0003824616,0.000056665718,0.00087032793,0.0007715563,0.00033027155],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0024824988,0.00029405212,0.00039712508,0.00048700292,0.0002988212,0.0002488433,0.000624689,0.000104313214,0.002907762],"category_scores_gemma":[0.00018924005,0.00019248386,0.00033267756,0.0014452767,0.00082236336,0.00025306517,0.0003653722,0.0012599917,0.00046754468],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032846124,0.0014908693,0.15048067,0.00015708251,0.010941017,0.00035573955,0.0022249976,0.0000013022911,0.3517343,0.00090257736,0.09105851,0.38736832],"study_design_scores_gemma":[0.0038206382,0.001542402,0.42015213,0.0004603916,0.0005518784,0.00019393675,0.0004346885,0.0014102223,0.11144978,0.00063947355,0.45897704,0.00036740844],"about_ca_topic_score_codex":0.0011211451,"about_ca_topic_score_gemma":0.00004483834,"teacher_disagreement_score":0.38700092,"about_ca_system_score_codex":0.000048609007,"about_ca_system_score_gemma":0.0009190626,"threshold_uncertainty_score":0.9980037},"labels":[],"label_agreement":null},{"id":"W4400868718","doi":"10.1186/s13195-024-01509-5","title":"Hormone therapy is associated with lower Alzheimer’s disease tau biomarkers in post-menopausal females -evidence from two independent cohorts","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Menopause: Health Impacts and Treatments","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill Genome Centre; Montreal Neurological Institute and Hospital; McGill University","funders":"Fonds de Recherche du Québec - Santé; National Institutes of Health; UK Dementia Research Institute; Vetenskapsrådet; Hjärnfonden; Familjen Erling-Perssons Stiftelse; Stiftelsen för Gamla Tjänarinnor; McGill University; Fondation Brain Canada; European Commission; Alzheimer's Disease Neuroimaging Initiative; Montreal Neurological Institute and Hospital; Servier; EU Joint Programme – Neurodegenerative Disease Research; HORIZON EUROPE Framework Programme; University of Southern California; Canadian Institutes of Health Research; Weston Brain Institute; Northern California Institute for Research and Education; Alzheimer's Drug Discovery Foundation; Consortium canadien en neurodégénérescence associée au vieillissement; Alzheimer's Association","keywords":"Biomarker; Dementia; Medicine; Positron emission tomography; Internal medicine; Oncology; Cognitive decline; Neuroimaging; Magnetic resonance imaging; Neurology; Hormone therapy; Menopause; Standardized uptake value; Psychology; Cohort; Disease; Endocrinology; Breast cancer; Nuclear medicine; Psychiatry; Cancer; Radiology","score_opus":0.18878759419485444,"score_gpt":0.43366382919673924,"score_spread":0.2448762350018848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400868718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6591153,0.3300842,0.0000032778744,0.0075274585,0.00017790053,0.0026688376,0.00015058168,0.00013478102,0.00013761994],"genre_scores_gemma":[0.9538607,0.043214485,0.00009229032,0.001459546,0.00024396156,0.0004252767,0.00028842458,0.0001758091,0.00023950911],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99303347,0.0008407156,0.0006628989,0.0013129873,0.002531794,0.0016181497],"domain_scores_gemma":[0.9957361,0.0011129576,0.00011941991,0.0010987098,0.00053800485,0.0013948096],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0021066018,0.00062155246,0.0007830023,0.00076936476,0.0003139904,0.00033215742,0.00041734747,0.00022068812,0.0016265828],"category_scores_gemma":[0.00017612564,0.00041909263,0.000060487397,0.0014694643,0.00042694074,0.0006005471,0.000107971005,0.0010849793,0.00029648683],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.118507154,0.006962687,0.25202668,0.00011458933,0.10316759,0.03969373,0.011767717,0.000023586677,0.1541965,0.00012850334,0.029652836,0.28375843],"study_design_scores_gemma":[0.024893431,0.030587379,0.92300624,0.003104434,0.0017152296,0.00006657706,0.00030744617,0.0007799186,0.0073756226,0.0005054185,0.006448053,0.001210278],"about_ca_topic_score_codex":0.010815337,"about_ca_topic_score_gemma":0.00053848885,"teacher_disagreement_score":0.67097956,"about_ca_system_score_codex":0.0003707658,"about_ca_system_score_gemma":0.0020581242,"threshold_uncertainty_score":0.9998261},"labels":[],"label_agreement":null},{"id":"W4401694572","doi":"10.1186/s13195-024-01555-z","title":"Performance of plasma p-tau217 for the detection of amyloid-β positivity in a memory clinic cohort using an electrochemiluminescence immunoassay","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"Health Research Board; Health Service Executive; Wellcome Trust; Meath Foundation; Canadian Institute for Theoretical Astrophysics","keywords":"Electrochemiluminescence; Immunoassay; Geriatric psychiatry; Medicine; Neurology; Cohort; Internal medicine; Oncology; Psychiatry; Chromatography; Chemistry; Immunology; Antibody; Detection limit","score_opus":0.10636414318213894,"score_gpt":0.41542754909151614,"score_spread":0.3090634059093772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401694572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93327147,0.064098865,0.000053605338,0.00012000337,0.00006222057,0.0022017383,0.000021573213,0.000026137739,0.00014438527],"genre_scores_gemma":[0.9919332,0.0074070077,0.000119116696,0.000013832013,0.0000998824,0.00032859307,0.000023759978,0.00004553982,0.000029047267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972748,0.0003180543,0.00041867813,0.00043289928,0.0009141137,0.0006414588],"domain_scores_gemma":[0.9976677,0.0010054559,0.000069136986,0.0005877925,0.00050892105,0.00016102548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025883494,0.00019085393,0.00038070095,0.00039182082,0.00017669435,0.000031991796,0.0002674613,0.000114431525,0.000055938865],"category_scores_gemma":[0.00009806209,0.00013058142,0.00018740958,0.0009455241,0.00047527422,0.00026882975,0.00005437516,0.0005279418,0.000010310094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012547814,0.0018247474,0.038128085,0.00028387544,0.016644211,0.000050185274,0.00069837604,0.000015555892,0.76794606,0.000012779832,0.00004794719,0.16180034],"study_design_scores_gemma":[0.0024081024,0.0037133105,0.057435118,0.0003199238,0.0004884158,0.000038765953,0.00023053582,0.039728783,0.89532655,0.000047149453,0.00011211682,0.00015123808],"about_ca_topic_score_codex":0.0008024361,"about_ca_topic_score_gemma":0.00004732699,"teacher_disagreement_score":0.16164911,"about_ca_system_score_codex":0.000114767194,"about_ca_system_score_gemma":0.0008185452,"threshold_uncertainty_score":0.53249556},"labels":[],"label_agreement":null},{"id":"W4401702455","doi":"10.1186/s13195-024-01554-0","title":"Risk factors for cognitive decline in non-demented elders with amyloid-beta positivity","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; University of California, San Francisco; National Institutes of Health; IXICO; H. Lundbeck A/S; Jewish General Hospital; University of California, Davis; Eisai; National Natural Science Foundation of China; Northern California Institute for Research and Education; USF Health Byrd Alzheimer's Institute; McGill University; Biogen; Northwestern University; Pfizer; BioClinica; University of California, Irvine; Georgetown University; Servier; Wake Forest University; Novartis Pharmaceuticals Corporation; Ohio State University; University of Southern California; Dartmouth College; U.S. Department of Defense; Eli Lilly and Company; Cleveland Clinic; Bristol-Myers Squibb; Genentech; University of South Florida; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Alzheimer's Association; Case Western Reserve University; Brigham and Women's Hospital","keywords":"Geriatric psychiatry; Neurology; Cognitive decline; Dementia; Gerontology; Medicine; Cognition; Amyloid (mycology); Brain aging; Psychology; Internal medicine; Psychiatry; Disease; Pathology","score_opus":0.07627242289309524,"score_gpt":0.4202344146082179,"score_spread":0.34396199171512265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401702455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98213893,0.005938009,0.0017822968,0.0026838654,0.000074477044,0.004744464,0.00012484832,0.00008921364,0.0024239216],"genre_scores_gemma":[0.99499243,0.002613157,0.0001735617,0.00030931228,0.00014878131,0.00084823766,0.0002317878,0.00008825487,0.0005944727],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99577713,0.00048805165,0.00032707682,0.00079060247,0.0014370458,0.0011801128],"domain_scores_gemma":[0.99644965,0.0020670996,0.000039591294,0.00030253615,0.00078820717,0.00035289722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002745852,0.00031381327,0.00041801741,0.0008877387,0.0002611792,0.00020518336,0.00021935075,0.00012844907,0.00052387756],"category_scores_gemma":[0.00017721925,0.00021766873,0.00018471645,0.0013636141,0.00044038525,0.00028587054,0.000115064846,0.001055143,0.00009594571],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01293353,0.0021882276,0.65693814,0.00014974017,0.007455339,0.0004078139,0.0026966895,0.0000018891543,0.01668001,0.00014729211,0.0023089845,0.29809237],"study_design_scores_gemma":[0.013266865,0.011528352,0.8078652,0.0007924527,0.0005135345,0.000020002153,0.0035982789,0.001175317,0.14860924,0.0005823047,0.011548022,0.000500456],"about_ca_topic_score_codex":0.0012781735,"about_ca_topic_score_gemma":0.0003252533,"teacher_disagreement_score":0.29759192,"about_ca_system_score_codex":0.00009680125,"about_ca_system_score_gemma":0.00051551213,"threshold_uncertainty_score":0.8876273},"labels":[],"label_agreement":null},{"id":"W4401793506","doi":"10.1186/s13195-024-01545-1","title":"Rationale and design of the BeyeOMARKER study: prospective evaluation of blood- and eye-based biomarkers for early detection of Alzheimer’s disease pathology in the eye clinic","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Optina Diagnostics (Canada)","funders":"","keywords":"Medicine; Disease; Neurology; Referral; Population; Intensive care medicine; Pathology; Psychiatry; Family medicine","score_opus":0.16385261452311498,"score_gpt":0.4517911037916173,"score_spread":0.2879384892685023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401793506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9644211,0.023796046,0.00020070994,0.00081284746,0.000036487978,0.010649077,0.000024194102,0.0000059733666,0.000053592477],"genre_scores_gemma":[0.9978313,0.00037505594,0.000067020665,0.00003131383,0.000026024705,0.0016228136,0.0000068668046,0.00001775079,0.000021882133],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99542737,0.0023762838,0.00036974347,0.00034345398,0.0012434116,0.00023974139],"domain_scores_gemma":[0.99736863,0.0012515399,0.000080032536,0.00029368195,0.0009449574,0.0000611615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.010615065,0.00011755699,0.00022548376,0.00035646738,0.00010815149,0.000028390192,0.0001305203,0.00005555764,0.0000537668],"category_scores_gemma":[0.0004689204,0.00006939041,0.00008814204,0.0006787954,0.00060259976,0.000093429735,0.000044445165,0.00022812303,7.661857e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010827602,0.0026688369,0.773859,0.00014784976,0.004513189,0.000014253247,0.0039106067,0.000006101286,0.0994372,0.000058058486,0.000078746685,0.1044785],"study_design_scores_gemma":[0.005312407,0.003950306,0.9528188,0.000102199796,0.0012376811,0.0000014763135,0.00091563,0.0026587995,0.031758435,0.0011564024,0.000026861915,0.00006099902],"about_ca_topic_score_codex":0.000079636164,"about_ca_topic_score_gemma":0.000017675147,"teacher_disagreement_score":0.17895974,"about_ca_system_score_codex":0.000015800084,"about_ca_system_score_gemma":0.0005708019,"threshold_uncertainty_score":0.3678991},"labels":[],"label_agreement":null},{"id":"W4402483367","doi":"10.1186/s13195-024-01564-y","title":"Impact of amyloid and cardiometabolic risk factors on prognostic capacity of plasma neurofilament light chain for neurodegeneration","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; Genentech; National Institutes of Health; IXICO; H. Lundbeck A/S; Servier; Eisai; Meso Scale Diagnostics; National Research Foundation of Korea; Ministry of Food and Drug Safety; National Research Foundation; Northern California Institute for Research and Education; Ministry of Trade, Industry and Energy; BioClinica; Biogen; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Korea Medical Device Development Fund; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Ministry of Science and ICT, South Korea; Seoul National University; Alzheimer's Disease Neuroimaging Initiative; Alzheimer's Association","keywords":"Medicine; Internal medicine; Cognitive decline; Biomarker; Dementia; Neurodegeneration; Cardiology; Oncology; Disease","score_opus":0.10603124753691556,"score_gpt":0.399526287765419,"score_spread":0.2934950402285034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402483367","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922373,0.0043005706,0.000069599664,0.00031311542,0.00008811294,0.0025807421,0.00012545139,0.00002819869,0.00025690408],"genre_scores_gemma":[0.9962664,0.003160551,0.00005497977,0.000014382768,0.000120551726,0.00021821933,0.00003818282,0.00004266104,0.000084044],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99722505,0.00048987323,0.00031945197,0.00043679733,0.0010312885,0.00049752236],"domain_scores_gemma":[0.9981562,0.0007485399,0.00005943398,0.0002998908,0.0005173638,0.0002185859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014059279,0.00020073661,0.00041389227,0.0007714746,0.000116917465,0.000061711,0.00011695955,0.000074321906,0.00007519455],"category_scores_gemma":[0.00031934094,0.00013394498,0.0002710408,0.0006895173,0.00022311117,0.00010563154,0.000046297366,0.000412686,0.0000059526237],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00304876,0.001174036,0.2728695,0.00022382381,0.005471782,0.000016831978,0.0019357569,0.00002943001,0.55378205,0.00043181964,0.00117662,0.15983962],"study_design_scores_gemma":[0.0018049895,0.012178257,0.5182598,0.000091990725,0.00024702068,0.0000060425036,0.0000931535,0.0019673398,0.4634792,0.00012603508,0.0016226595,0.00012352096],"about_ca_topic_score_codex":0.00042350576,"about_ca_topic_score_gemma":0.000005434383,"teacher_disagreement_score":0.2453903,"about_ca_system_score_codex":0.000036316986,"about_ca_system_score_gemma":0.00027545547,"threshold_uncertainty_score":0.5462118},"labels":[],"label_agreement":null},{"id":"W4403067023","doi":"10.1186/s13195-024-01575-9","title":"Brain Iron in signature regions relating to cognitive aging in older adults: the Taizhou Imaging Study","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Huashan Hospital; Fudan University; Government of Jiangsu Province","keywords":"Cognitive aging; Geriatric psychiatry; Neurology; Cognition; Brain aging; Signature (topology); Psychology; Medicine; Gerontology; Neuroscience; Psychiatry","score_opus":0.054311618606537285,"score_gpt":0.42561542395568325,"score_spread":0.371303805349146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403067023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92435557,0.027910799,0.00006914645,0.037376523,0.00009595589,0.006237132,0.000005818803,0.00008516524,0.0038638958],"genre_scores_gemma":[0.99557805,0.0004348534,0.00002923477,0.001662908,0.00020704887,0.001053491,0.00001937762,0.00007085525,0.00094419555],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99473155,0.0014093929,0.00041014404,0.00082638965,0.0014859048,0.0011366251],"domain_scores_gemma":[0.9968832,0.0020860464,0.000025022455,0.00039772838,0.00037979396,0.0002282209],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.005228587,0.00025597983,0.00029218826,0.001316953,0.00026945464,0.0002613233,0.00033162552,0.00007923922,0.00030698208],"category_scores_gemma":[0.0005695075,0.00017648,0.000101143254,0.0030719389,0.0002053041,0.00028871262,0.00024465797,0.0023881781,0.00016384732],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019378514,0.002122909,0.3758426,0.00007859972,0.00070865004,0.0026938256,0.064958125,0.000006968935,0.0025669746,0.00021743367,0.010457549,0.5384085],"study_design_scores_gemma":[0.009916871,0.0021757456,0.85747516,0.0046809195,0.00010120634,0.000055532466,0.11353452,0.002588627,0.0016743399,0.000513116,0.0068034623,0.00048049216],"about_ca_topic_score_codex":0.001228053,"about_ca_topic_score_gemma":0.00054559746,"teacher_disagreement_score":0.53792804,"about_ca_system_score_codex":0.00014550149,"about_ca_system_score_gemma":0.00033029358,"threshold_uncertainty_score":0.99991333},"labels":[],"label_agreement":null},{"id":"W4403069953","doi":"10.1186/s13195-024-01580-y","title":"Cholinesterase inhibitor use in amyloid PET-negative mild cognitive impairment and cognitive changes","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institutes of Health; Soonchunhyang University; Northern California Institute for Research and Education; Canadian Institutes of Health Research; University of Southern California; Novartis Pharmaceuticals Corporation; Servier; Alzheimer's Disease Neuroimaging Initiative; Pfizer","keywords":"Cognitive decline; Dementia; Neuroimaging; Tauopathy; Cognition; Psychology; Neurology; Rivastigmine; Positron emission tomography; Frontal lobe; Medicine; Internal medicine; Alzheimer's Disease Neuroimaging Initiative; Alzheimer's disease; Effects of sleep deprivation on cognitive performance; Temporal lobe; Atrophy; Neuroscience; Disease; Donepezil; Neurodegeneration","score_opus":0.12367192061221273,"score_gpt":0.42004114349837945,"score_spread":0.29636922288616674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403069953","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9690309,0.022517495,0.000019084082,0.003152316,0.00012487218,0.0041603586,0.0001268826,0.00010552617,0.00076254166],"genre_scores_gemma":[0.9877615,0.0084564565,0.000085943786,0.00089920533,0.00040213042,0.0011789036,0.0001116867,0.000092372444,0.0010117989],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9950087,0.00084576505,0.00037526767,0.0010366417,0.0015004792,0.0012331464],"domain_scores_gemma":[0.99587554,0.0023978685,0.000038137467,0.0002412175,0.00090277346,0.00054444175],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019886084,0.000409966,0.00048174133,0.0014162712,0.00023177618,0.00048139438,0.00014114784,0.00010733591,0.00074939005],"category_scores_gemma":[0.00039238404,0.00032663575,0.0001234154,0.0014758015,0.0008216635,0.0005538835,0.00023172628,0.0012809448,0.00022855407],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.025639804,0.0056868084,0.29253912,0.0005930215,0.0088925585,0.010362898,0.021431778,3.1448937e-7,0.041477326,0.00022522532,0.004577527,0.58857363],"study_design_scores_gemma":[0.021126159,0.009402199,0.79741776,0.0051611625,0.0005359445,0.00041952176,0.010034541,0.000522996,0.1490946,0.00047109465,0.004838981,0.00097503205],"about_ca_topic_score_codex":0.0006428477,"about_ca_topic_score_gemma":0.0003234187,"teacher_disagreement_score":0.58759856,"about_ca_system_score_codex":0.000102817445,"about_ca_system_score_gemma":0.00039415128,"threshold_uncertainty_score":0.9999186},"labels":[],"label_agreement":null},{"id":"W4403557059","doi":"10.1186/s13195-024-01562-0","title":"Amyloid deposition and its association with depressive symptoms and cognitive functions in late-life depression: a longitudinal study using amyloid-β PET images and neuropsychological measurements","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Samsung; Korea Health Industry Development Institute; Ministry of Trade, Industry and Energy","keywords":"Geriatric psychiatry; Neuropsychology; Depression (economics); Neurology; Depressive symptoms; Amyloid (mycology); Late life depression; Association (psychology); Medicine; Cognition; Psychiatry; Clinical psychology; Psychology; Internal medicine; Pathology; Psychotherapist","score_opus":0.1368686521337048,"score_gpt":0.418341605282118,"score_spread":0.2814729531484132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403557059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9736803,0.023285255,0.00012595454,0.00040259442,0.00004008566,0.0021620565,0.000014592,0.000046429577,0.0002427298],"genre_scores_gemma":[0.99833035,0.0010367713,0.000032594013,0.00009757752,0.000077080316,0.00029468577,0.000017215794,0.000034441335,0.000079261175],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.996308,0.0008990136,0.000239764,0.0007637952,0.0012423004,0.00054706953],"domain_scores_gemma":[0.9984943,0.000488641,0.000047553953,0.00012331999,0.0005452862,0.00030088268],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014263502,0.00023123369,0.00029654874,0.00047809875,0.00035805296,0.0003396293,0.00006217543,0.00007137976,0.000091762115],"category_scores_gemma":[0.00019559757,0.00016558776,0.000032206302,0.00063144806,0.00018189466,0.00039769476,0.00012194051,0.00071384455,0.000008884959],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024553016,0.000701988,0.9526626,0.000030245432,0.0015966535,0.00055483147,0.0005658021,0.0000013464916,0.02672478,0.0000014361007,0.000043242897,0.014661807],"study_design_scores_gemma":[0.005101713,0.0025894153,0.98656917,0.0003520447,0.00041296406,0.00015603451,0.0006058107,0.0006864077,0.003327275,0.000019421175,0.000012555864,0.00016718604],"about_ca_topic_score_codex":0.00016557232,"about_ca_topic_score_gemma":0.000044043907,"teacher_disagreement_score":0.03390661,"about_ca_system_score_codex":0.00006382526,"about_ca_system_score_gemma":0.000120663084,"threshold_uncertainty_score":0.67524725},"labels":[],"label_agreement":null},{"id":"W4403691312","doi":"10.1186/s13195-024-01601-w","title":"Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; National Institute on Aging; Medical Research Council; Canadian Institutes of Health Research; Genentech; U.S. National Library of Medicine; National Institute of Neurological Disorders and Stroke; IXICO; Karl-Franzens-Universität Graz; National Institutes of Health; Österreichische Forschungsförderungsgesellschaft; Oesterreichische Nationalbank; Eisai; Austrian Science Fund; Medizinische Universität Graz; Texas Alzheimer's Research and Care Consortium; Vanderbilt University; EU Joint Programme – Neurodegenerative Disease Research; Biogen; University of Miami; BioClinica; Bristol-Myers Squibb; U.S. Department of Defense; Eli Lilly and Company; University of Pennsylvania; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust; University of Southern California; University of Toronto; National Science Foundation; Case Western Reserve University; Brigham and Women's Hospital; Alzheimer's Disease Neuroimaging Initiative; Alzheimer's Association; GHR Foundation; University of Washington","keywords":"Alzheimer's disease; Disease; Neurology; Geriatric psychiatry; Medicine; Mitochondrial DNA; Biomarker; Biology; Pathology; Psychiatry; Gene; Genetics","score_opus":0.04746016374615052,"score_gpt":0.3331954777773031,"score_spread":0.28573531403115254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403691312","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.780608,0.20959653,0.00008025439,0.0029254535,0.0016988056,0.002000436,0.00042611183,0.00022239899,0.002442043],"genre_scores_gemma":[0.98666644,0.008316843,0.00052482245,0.0009840478,0.00084342243,0.00031881937,0.0007135471,0.00020620802,0.0014258465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9955156,0.000985606,0.00045343846,0.0013264902,0.0007231874,0.0009956644],"domain_scores_gemma":[0.99790716,0.00024548685,0.000089561916,0.0007688223,0.0004323716,0.00055661885],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00074567075,0.00051441794,0.00044675526,0.0002445886,0.00039983756,0.00029269644,0.00040742764,0.00048169904,0.0017268992],"category_scores_gemma":[0.0001335666,0.00041075377,0.00024149269,0.00080689107,0.0007959963,0.000039161805,0.00018751268,0.00058097485,0.00022518206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034595798,0.00045142326,0.005800838,0.000013114293,0.03343018,0.0003212051,0.00071566046,0.0000035130995,0.87917125,0.00056070974,0.061507374,0.014565154],"study_design_scores_gemma":[0.0059476104,0.0015707748,0.004788792,0.000116131785,0.0028345245,0.00018000002,0.00017745895,0.0001521892,0.6737289,0.0009051902,0.30830768,0.0012907645],"about_ca_topic_score_codex":0.00008341946,"about_ca_topic_score_gemma":0.000033225293,"teacher_disagreement_score":0.2468003,"about_ca_system_score_codex":0.000010189892,"about_ca_system_score_gemma":0.00041912872,"threshold_uncertainty_score":0.9998344},"labels":[],"label_agreement":null},{"id":"W4405569139","doi":"10.1186/s13195-024-01626-1","title":"Impact of gender on the willingness to participate in clinical trials and undergo related procedures in individuals from an Alzheimer’s prevention research cohort","year":2024,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; Occupational Cancer Research Centre; University of Toronto; University Health Network","funders":"Instituto de Salud Carlos III; European Commission; European Regional Development Fund; Horizon 2020 Framework Programme; Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona; Ministerio de Ciencia e Innovación; Global Brain Health Institute; Alzheimer's Society; Ministerstvo Školství, Mládeže a Tělovýchovy; Agencia Estatal de Investigación; “la Caixa” Foundation; Alzheimer's Association","keywords":"Medicine; Clinical trial; Cohort; Context (archaeology); Disease; Cohort study; Internal medicine","score_opus":0.8946323707937676,"score_gpt":0.732799134117218,"score_spread":0.16183323667654959,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405569139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9597163,0.021560522,0.0000057176553,0.012422404,0.00012096937,0.005583963,0.00003721013,0.000042887586,0.0005099982],"genre_scores_gemma":[0.9812198,0.017172894,0.00011624739,0.0002185099,0.00025647794,0.00076869095,0.000034351644,0.0000949721,0.0001180166],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9703446,0.020102598,0.002564624,0.0014271287,0.0042246166,0.001336417],"domain_scores_gemma":[0.8797983,0.11594652,0.000179516,0.0017559219,0.0014257253,0.00089399714],"candidate_categories":["metaresearch","research_integrity"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.2065381,0.00030916766,0.0012058378,0.0012767427,0.0001924814,0.00025741098,0.0008138015,0.0008714866,0.00066996913],"category_scores_gemma":[0.053849347,0.000188208,0.0003434474,0.0031699438,0.0013879471,0.00024585307,0.0003786901,0.007886788,0.000110680856],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0080669345,0.004085048,0.86664796,0.000121255216,0.009826572,0.00020711863,0.011088812,0.00011961225,0.00380001,0.010777619,0.0035350283,0.081724],"study_design_scores_gemma":[0.0026560442,0.0063997423,0.8480669,0.001433573,0.00015393745,0.00000379295,0.00081883336,0.00096445566,0.0018656964,0.13712968,0.0002922238,0.00021511487],"about_ca_topic_score_codex":0.0025105635,"about_ca_topic_score_gemma":0.001186609,"teacher_disagreement_score":0.15268874,"about_ca_system_score_codex":0.00016405963,"about_ca_system_score_gemma":0.0037137638,"threshold_uncertainty_score":0.99440205},"labels":[],"label_agreement":null},{"id":"W4406002904","doi":"10.1186/s13195-024-01665-8","title":"Cerebrospinal fluid β2-microglobulin promotes the tau pathology through microglia–astrocyte communication in Alzheimer's disease","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; National Institute on Aging; Alzheimer's Association","keywords":"Cerebrospinal fluid; Glial fibrillary acidic protein; Neurodegeneration; Medicine; Microglia; Pathology; Alzheimer's disease; Pathogenesis; Tau protein; Neurology; Astrocyte; Amyloid beta; Internal medicine; Disease; Immunohistochemistry; Central nervous system; Psychiatry; Inflammation","score_opus":0.08315557181781294,"score_gpt":0.4031671520684553,"score_spread":0.32001158025064236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406002904","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.37789762,0.58594364,0.000033165463,0.028173316,0.00012306357,0.00539535,0.00008894278,0.00014627643,0.0021985976],"genre_scores_gemma":[0.97519666,0.0207715,0.0007273699,0.0013385337,0.0001323337,0.0013059608,0.00028941434,0.00007898874,0.00015921629],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99359053,0.0019265392,0.0006921926,0.0009698273,0.0011891103,0.0016317739],"domain_scores_gemma":[0.99562806,0.0006844161,0.000111254994,0.0023161971,0.0007269298,0.00053312664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018186094,0.0005012121,0.0006332804,0.0005057738,0.0008972167,0.00019749727,0.0011574231,0.00022552405,0.00034134372],"category_scores_gemma":[0.00020150428,0.00035266142,0.00032806786,0.0016292724,0.0016001941,0.00034792477,0.0005440936,0.0014514409,0.00039504762],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.05603826,0.023575014,0.3270066,0.00028416628,0.11578884,0.005045577,0.007475072,0.00003726032,0.020404277,0.017143723,0.077708736,0.34949246],"study_design_scores_gemma":[0.038762894,0.0055352882,0.6855782,0.001990464,0.0049658734,0.00027651887,0.0034625304,0.000888053,0.11620268,0.036763597,0.10357409,0.0019997915],"about_ca_topic_score_codex":0.0010095608,"about_ca_topic_score_gemma":0.00009708488,"teacher_disagreement_score":0.59729904,"about_ca_system_score_codex":0.00019658494,"about_ca_system_score_gemma":0.0016806143,"threshold_uncertainty_score":0.99989253},"labels":[],"label_agreement":null},{"id":"W4406033262","doi":"10.1186/s13195-024-01659-6","title":"Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; Instituto de Salud Carlos III; Fonds de Recherche du Québec - Santé; National Institutes of Health; Deutsches Zentrum für Neurodegenerative Erkrankungen; National Institute of Neurological Disorders and Stroke; Korea Health Industry Development Institute; Japan Agency for Medical Research and Development; University of California, San Diego; Fondation Brain Canada; Fleni; European Molecular Biology Laboratory; National Institute on Aging; Alzheimer's Association; National Heart, Lung, and Blood Institute; Cure Alzheimer's Fund; National Cancer Institute; Eidgenössische Technische Hochschule Zürich; U.S. National Library of Medicine; U.S. Department of Veterans Affairs; Canadian Institutes of Health Research; National Science Foundation","keywords":"PSEN1; Disease; Presenilin; Medicine; Dementia; Bioinformatics; Alzheimer's disease; Neurology; Mutation; Neurodegeneration; Neuroscience; Genetics; Biology; Gene; Psychiatry; Pathology","score_opus":0.09382370023339882,"score_gpt":0.45081230381452914,"score_spread":0.3569886035811303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406033262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.76341796,0.224654,0.000022297545,0.00445343,0.00016094348,0.004195806,0.00035183673,0.00013167264,0.0026120672],"genre_scores_gemma":[0.9870026,0.010581064,0.0003371488,0.00046146766,0.00012973598,0.0008263447,0.00030866,0.00006049081,0.00029250194],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9953786,0.00086453673,0.0005665278,0.000885879,0.0010177322,0.0012867333],"domain_scores_gemma":[0.99648273,0.001113125,0.000074046,0.0008293556,0.0006062554,0.00089446985],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011046331,0.00044064046,0.0006722489,0.0007212024,0.00060057064,0.0001715225,0.00034554512,0.00018333734,0.00008988784],"category_scores_gemma":[0.0002838986,0.00034998616,0.00020144256,0.0013845612,0.0011611609,0.0003193437,0.00025730275,0.0010124678,0.00011365249],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022935003,0.007640845,0.46712506,0.00013813788,0.055186376,0.0022483186,0.007585051,0.000024484714,0.00220171,0.0060883807,0.0107047735,0.41812184],"study_design_scores_gemma":[0.0279302,0.002063028,0.92009616,0.0009717335,0.002135822,0.000037670885,0.008461875,0.0021734424,0.0078961,0.019051395,0.008130032,0.0010525114],"about_ca_topic_score_codex":0.0016844657,"about_ca_topic_score_gemma":0.0003981996,"teacher_disagreement_score":0.45297113,"about_ca_system_score_codex":0.00013821502,"about_ca_system_score_gemma":0.0009138732,"threshold_uncertainty_score":0.9998952},"labels":[],"label_agreement":null},{"id":"W4406354311","doi":"10.1186/s13195-024-01661-y","title":"Exome sequencing reveals a rare damaging variant in GRIN2C in familial late-onset Alzheimer's disease","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Dipartimenti di Eccellenza; Università degli Studi di Torino; Consortium canadien en neurodégénérescence associée au vieillissement; Associazione Italiana Ricerca Alzheimer; Fondazione CRT","keywords":"PSEN1; Exome sequencing; Missense mutation; Genetics; Biology; Exome; Early-onset Alzheimer's disease; Alzheimer's disease; Mutation; Gene; Medicine; Disease; Presenilin; Internal medicine","score_opus":0.08014388194071793,"score_gpt":0.3905617551295269,"score_spread":0.310417873188809,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406354311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9645768,0.030498894,0.00008789798,0.0018307045,0.00023319374,0.0013005926,0.000050698534,0.000027670829,0.0013935572],"genre_scores_gemma":[0.9956544,0.0021815102,0.00026624522,0.0006263353,0.00013811233,0.0005465081,0.00011270017,0.000044150835,0.00043001675],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9966654,0.0008950742,0.00045199253,0.00076655316,0.00039257918,0.00082838064],"domain_scores_gemma":[0.9984875,0.00015504289,0.000057666788,0.0008896898,0.00021863721,0.00019150124],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014365889,0.0002594384,0.00026500464,0.0006163539,0.00018415347,0.0001056057,0.00062426523,0.00017865076,0.00009375596],"category_scores_gemma":[0.0002990607,0.00025907237,0.00011793554,0.000890763,0.00019601309,0.00003125267,0.00032709792,0.0007234753,0.00003678041],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004686949,0.000998306,0.14016321,0.000056641256,0.002317638,0.0017637557,0.0016242289,0.0009916642,0.78504014,0.0007924946,0.008864629,0.052700315],"study_design_scores_gemma":[0.013930735,0.0014463455,0.4814086,0.0017319132,0.00026722762,0.00012256957,0.0027913114,0.0028563796,0.36060053,0.015918557,0.11611174,0.002814098],"about_ca_topic_score_codex":0.0017219168,"about_ca_topic_score_gemma":0.00058956386,"teacher_disagreement_score":0.42443964,"about_ca_system_score_codex":0.00010477958,"about_ca_system_score_gemma":0.00076036865,"threshold_uncertainty_score":0.9999862},"labels":[],"label_agreement":null},{"id":"W4406552203","doi":"10.1186/s13195-025-01674-1","title":"Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer’s model","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Locus coeruleus; Neuroinflammation; Neurodegeneration; Tauopathy; Medicine; Neurology; Inflammation; Hippocampus; Neuroscience; Internal medicine; Pathology; Psychology; Disease; Central nervous system","score_opus":0.10086775585554185,"score_gpt":0.4170457303892538,"score_spread":0.31617797453371194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406552203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96077293,0.03657267,0.00034759124,0.00092960976,0.000091492344,0.0009933852,0.000009718898,0.000015464337,0.0002671123],"genre_scores_gemma":[0.9926393,0.006268119,0.00035611624,0.00021985955,0.00013334837,0.00016163678,0.000103285165,0.000018936587,0.00009940585],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978663,0.00053771446,0.0003595028,0.0005878631,0.00015965813,0.0004890179],"domain_scores_gemma":[0.99927837,0.00011673607,0.000073832925,0.00019462641,0.000259081,0.000077383316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001510245,0.00016903355,0.00020949559,0.000195595,0.00021604275,0.00006196613,0.00016260476,0.00028120374,0.000010574279],"category_scores_gemma":[0.00016063891,0.00015315333,0.00004818757,0.00027251508,0.0003099792,0.000021196096,0.00013124202,0.00042354627,0.000009581293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019604727,0.0001305673,0.0021344523,0.000014403395,0.00037673552,0.0000024186202,0.0005227875,0.000028734705,0.96472496,0.00010949597,0.0006033068,0.029391678],"study_design_scores_gemma":[0.005286144,0.0050587365,0.07671828,0.0003135045,0.00021259247,0.000006297286,0.0011091686,0.0021097197,0.9008927,0.004542073,0.003058428,0.0006924152],"about_ca_topic_score_codex":0.0000742383,"about_ca_topic_score_gemma":0.00006867796,"teacher_disagreement_score":0.07458382,"about_ca_system_score_codex":0.000010315112,"about_ca_system_score_gemma":0.00031989912,"threshold_uncertainty_score":0.62454116},"labels":[],"label_agreement":null},{"id":"W4407132430","doi":"10.1186/s13195-025-01677-y","title":"A systematic review and meta-analysis of the impact of transcranial direct current stimulation on cognitive function in older adults with cognitive impairments: the influence of dosage parameters","year":2025,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Transcranial Magnetic Stimulation Studies","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Mahidol University","keywords":"Transcranial direct-current stimulation; Meta-analysis; Cognition; Physical medicine and rehabilitation; Geriatric psychiatry; Neurology; Medicine; Psychology; Brain stimulation; Clinical psychology; Stimulation; Neuroscience; Psychiatry; Internal medicine","score_opus":0.17730768367066665,"score_gpt":0.45159034105017226,"score_spread":0.27428265737950563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407132430","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009795846,0.97508055,0.000021654496,0.000029988767,0.000015292228,0.014387951,0.0006332895,0.000008020277,0.00002739999],"genre_scores_gemma":[0.42306507,0.5759439,0.0000012654148,0.000027021768,0.0000018116551,0.0009362293,0.000006924048,0.000014485718,0.0000032663243],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9907214,0.0056467075,0.0013544821,0.0006538495,0.0013048005,0.00031873054],"domain_scores_gemma":[0.9849188,0.012848886,0.00091584213,0.0005567634,0.0007108674,0.000048867445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001749405,0.0004822025,0.004226369,0.00082087226,0.0001293715,0.000025559444,0.00045665167,0.000095791285,0.000052378487],"category_scores_gemma":[0.0013154483,0.00020569036,0.0016359122,0.0053092977,0.0008063756,0.00011483445,0.00005395366,0.0005455516,0.0000010840117],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004963547,0.0024487174,0.00013652992,0.46979043,0.42026818,0.0000063385396,0.007944662,0.0019315446,0.00006154429,0.00003611743,0.000009970643,0.092402406],"study_design_scores_gemma":[0.002680623,0.0023245425,0.011642447,0.20076711,0.7819015,0.0000022912225,0.00015280105,0.000101786085,0.000044753622,0.000018895953,0.0000096222,0.00035364032],"about_ca_topic_score_codex":0.0003702501,"about_ca_topic_score_gemma":0.000035888894,"teacher_disagreement_score":0.41326922,"about_ca_system_score_codex":0.00003537738,"about_ca_system_score_gemma":0.00027130698,"threshold_uncertainty_score":0.838781},"labels":[],"label_agreement":null},{"id":"W4407753426","doi":"10.1186/s13195-025-01692-z","title":"The impact of kidney function on Alzheimer’s disease blood biomarkers: implications for predicting amyloid-β positivity","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; HORIZON EUROPE Framework Programme; Hjärnfonden; University College London; National Institute for Health and Care Research; EU Joint Programme – Neurodegenerative Disease Research; Familjen Erling-Perssons Stiftelse; Stiftelsen för Gamla Tjänarinnor; European Commission; Fondation Brain Canada; National Institute on Aging; Consortium canadien en neurodégénérescence associée au vieillissement; Alzheimer's Association; UK Dementia Research Institute; Vetenskapsrådet; Cure Alzheimer's Fund; Alzheimer's Drug Discovery Foundation","keywords":"Medicine; Biomarker; Renal function; Internal medicine; Dementia; Kidney disease; Oncology; Creatinine; Cohort; Cystatin C; Neurology; Pathology; Disease; Gastroenterology; Psychiatry; Biology","score_opus":0.08926995974367784,"score_gpt":0.4281450500785648,"score_spread":0.33887509033488694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407753426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7417595,0.17613623,0.00032963933,0.057242386,0.0004586031,0.011507232,0.001711318,0.00032379778,0.010531322],"genre_scores_gemma":[0.99576867,0.0018265279,0.000034428936,0.0009724095,0.00021204088,0.00080151245,0.00023224448,0.000037912218,0.00011425466],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9977505,0.00028756625,0.00035764888,0.0004688542,0.00044076052,0.0006946345],"domain_scores_gemma":[0.9955671,0.00178405,0.00009568902,0.0010039305,0.00068273646,0.0008664955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012531123,0.00022752988,0.000290004,0.00031199696,0.0007363935,0.000082585655,0.00028534452,0.0000949314,0.000069917114],"category_scores_gemma":[0.0010871068,0.00014719674,0.00048779076,0.0008003834,0.0003816517,0.00012301882,0.000072494244,0.00029385698,0.000010527775],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024832113,0.005127146,0.22429225,0.0001263189,0.041877527,0.0000060848524,0.00023012707,0.000015165459,0.080786854,0.0061883754,0.24677786,0.3697402],"study_design_scores_gemma":[0.01219079,0.0051329657,0.89563555,0.0006295891,0.0041725384,0.000002834272,0.00018914205,0.0015099194,0.039099216,0.012610843,0.02842939,0.0003972077],"about_ca_topic_score_codex":0.00032254143,"about_ca_topic_score_gemma":0.0000046485748,"teacher_disagreement_score":0.6713433,"about_ca_system_score_codex":0.000085322026,"about_ca_system_score_gemma":0.0030864943,"threshold_uncertainty_score":0.60025084},"labels":[],"label_agreement":null},{"id":"W4408105335","doi":"10.1186/s13195-025-01703-z","title":"Synaptic protein CSF levels relate to memory scores in individuals without dementia","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; Genentech; National Institutes of Health; UK Dementia Research Institute; IXICO; H. Lundbeck A/S; Servier; Innovative Medicines Initiative; Alzheimer's Drug Discovery Foundation; ZonMw; Alzheimerfonden; European Commission; Familjen Erling-Perssons Stiftelse; Hjärnfonden; Vetenskapsrådet; Eisai; EU Joint Programme – Neurodegenerative Disease Research; European Research Council; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; University of Southern California; Alzheimer's Association; Stiftelsen för Gamla Tjänarinnor; Eli Lilly and Company; U.S. Department of Defense; Demensfonden; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Demensförbundet; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb","keywords":"Biomarker; Dementia; Neuroscience; Neurology; Neuroimaging; Recall; Amyloid (mycology); Cognition; Disease; Medicine; Psychology; Oncology; Internal medicine; Pathology; Biology; Biochemistry; Cognitive psychology","score_opus":0.09962716563732651,"score_gpt":0.42246745014213366,"score_spread":0.3228402845048072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408105335","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9575643,0.012426353,0.0001266607,0.008982829,0.00007231932,0.0061990363,0.000009656597,0.00007616376,0.0145427035],"genre_scores_gemma":[0.9915533,0.0003892691,0.000716767,0.0012798164,0.000070050046,0.001608136,0.000015735477,0.000048759957,0.004318182],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9947677,0.00092560955,0.0005134713,0.00075914536,0.0017024195,0.0013316283],"domain_scores_gemma":[0.9979592,0.00026771094,0.000043968626,0.00069805724,0.00065104174,0.0003800228],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0044278386,0.00028172057,0.0004686998,0.001752419,0.00025924674,0.00017026035,0.0005230315,0.00016087844,0.0013999379],"category_scores_gemma":[0.0004221938,0.00023520274,0.00011910963,0.0021127965,0.00032014374,0.00022916045,0.000369421,0.0010569436,0.0005915124],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020910925,0.0017151829,0.62051594,0.00012058981,0.009207218,0.00021083349,0.001577888,0.0000043754267,0.11339136,0.0011374388,0.007167378,0.2428607],"study_design_scores_gemma":[0.008270047,0.002418673,0.80033064,0.0011061219,0.0002089968,0.000010269366,0.0006641298,0.00006993699,0.16320185,0.0032384903,0.020082757,0.0003981133],"about_ca_topic_score_codex":0.00038534382,"about_ca_topic_score_gemma":0.00007670328,"teacher_disagreement_score":0.2424626,"about_ca_system_score_codex":0.0001109728,"about_ca_system_score_gemma":0.0008119071,"threshold_uncertainty_score":0.9995129},"labels":[],"label_agreement":null},{"id":"W4408431596","doi":"10.1186/s13195-025-01706-w","title":"Beyond expectations: investigating nilotinib’s potential in attenuating neurodegeneration in Alzheimer’s disease","year":2025,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Institute on Aging","keywords":"Neurodegeneration; Neurology; Disease; Medicine; Geriatric psychiatry; Psychopharmacology; Neuroscience; Nilotinib; Psychology; Psychiatry; Internal medicine","score_opus":0.2501518016237052,"score_gpt":0.4991603195452006,"score_spread":0.24900851792149542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408431596","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00048213266,0.9894673,0.00000577906,0.0019676867,0.00026755154,0.006886416,0.00005230609,0.000085007785,0.0007857911],"genre_scores_gemma":[0.0023248217,0.9909578,0.00048716585,0.0002508555,0.0006662752,0.004568118,0.00042372008,0.00015377242,0.00016748978],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9904169,0.0029221126,0.0015297601,0.0014749396,0.0021640018,0.0014922766],"domain_scores_gemma":[0.9957158,0.0017438224,0.0002734145,0.00112886,0.0006203364,0.0005177969],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002642242,0.00072732975,0.0020342683,0.0029329113,0.00041345696,0.0002106228,0.00070100423,0.000315456,0.00009923387],"category_scores_gemma":[0.0022040687,0.0006262708,0.00046152293,0.003956101,0.0005198966,0.00032190958,0.00047674164,0.0028599775,0.00009225519],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020065019,0.00039626082,0.0010057858,0.0030543332,0.0014244799,0.0004341062,0.0010536487,0.00003391955,0.000030823812,0.00014987202,0.0026897348,0.9895264],"study_design_scores_gemma":[0.021969507,0.0033123018,0.011393573,0.18721023,0.008019058,0.00010441701,0.0042357068,0.0043780394,0.000344521,0.004694714,0.7485525,0.0057854396],"about_ca_topic_score_codex":0.00093240343,"about_ca_topic_score_gemma":0.00034858493,"teacher_disagreement_score":0.9837409,"about_ca_system_score_codex":0.00046608262,"about_ca_system_score_gemma":0.004981604,"threshold_uncertainty_score":0.9996189},"labels":[],"label_agreement":null},{"id":"W4409745378","doi":"10.1186/s13195-025-01742-6","title":"Differential effects of aging, Alzheimer's pathology, and APOE4 on longitudinal functional connectivity and episodic memory in older adults","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institut Universitaire de Gériatrie de Montréal; McGill University; Douglas Mental Health University Institute","funders":"Otto von Guericke University Magdeburg; Deutsche Forschungsgemeinschaft","keywords":"Precuneus; Parahippocampal gyrus; Episodic memory; Psychology; Neuroscience; Temporal lobe; Alzheimer's disease; Hippocampus; Neurology; Posterior cingulate; Cognition; Medicine; Disease; Pathology","score_opus":0.0768005484332302,"score_gpt":0.3504735666026848,"score_spread":0.2736730181694546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409745378","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98106396,0.013367436,0.000090596644,0.0034669728,0.00046565442,0.0011086388,0.000010315964,0.000042945765,0.00038345606],"genre_scores_gemma":[0.99755746,0.0013317307,0.000010505947,0.00069608644,0.00008299698,0.00023781255,0.0000020276061,0.000022212937,0.000059156962],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99630713,0.0011694407,0.00026511837,0.0010491925,0.0006541268,0.0005549775],"domain_scores_gemma":[0.9845075,0.014801397,0.00007109738,0.00037154442,0.00015169484,0.000096780364],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000714271,0.000278075,0.00042748393,0.00071208074,0.0003992397,0.00005310614,0.00020732477,0.00013440462,0.000059211907],"category_scores_gemma":[0.0022102776,0.00024428987,0.00007251102,0.0006776583,0.0012420693,0.00019465694,0.00031366432,0.0007028815,0.00000757397],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010469755,0.004802537,0.19967532,0.00042729432,0.002616584,0.0005775838,0.003965098,0.000052801144,0.27338564,0.01582307,0.0072902124,0.4809141],"study_design_scores_gemma":[0.004390211,0.0007522866,0.7615658,0.00018549516,0.000048602305,0.000022948143,0.00011335162,0.00029964471,0.22997648,0.0022122927,0.00021254271,0.00022032873],"about_ca_topic_score_codex":0.00029848024,"about_ca_topic_score_gemma":0.00014299403,"teacher_disagreement_score":0.5618905,"about_ca_system_score_codex":0.000032042037,"about_ca_system_score_gemma":0.00008795585,"threshold_uncertainty_score":0.9961851},"labels":[],"label_agreement":null},{"id":"W4409988625","doi":"10.1186/s13195-025-01745-3","title":"Prognostic value of plasma biomarkers for informing clinical trial design in mild-to-moderate Alzheimer’s disease","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"International Collaboration On Repair Discoveries; University of British Columbia","funders":"National Institute on Aging; University of California, San Diego; National Institutes of Health; Biohaven Pharmaceuticals","keywords":"Geriatric psychiatry; Neurology; Medicine; Disease; Clinical trial; Internal medicine; Value (mathematics); Alzheimer's disease; Oncology; Intensive care medicine; Psychiatry","score_opus":0.2803736202043071,"score_gpt":0.5065971823650064,"score_spread":0.22622356216069928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409988625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9618282,0.007517518,0.003274523,0.005117552,0.00033311875,0.020593315,0.00002918132,0.000054018918,0.0012525729],"genre_scores_gemma":[0.9918015,0.0010998012,0.0031343165,0.000621138,0.0001615216,0.0028041755,0.00004603293,0.00004750208,0.00028403103],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99474156,0.001211145,0.0010527135,0.00067799835,0.0012069937,0.0011095881],"domain_scores_gemma":[0.99397755,0.003824922,0.0000932669,0.000569313,0.0009355135,0.00059941615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008349648,0.0002708461,0.0006476022,0.0013204375,0.00019812917,0.000084545565,0.00044591576,0.00016247311,0.00010067641],"category_scores_gemma":[0.0023306743,0.0002247163,0.00032559707,0.0015451015,0.00042574957,0.00017759972,0.00018045558,0.00055901404,0.00003791719],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.54508877,0.0029590942,0.058109958,0.000090055815,0.00504224,0.00006118345,0.0002822359,0.00002634196,0.0011649901,0.0006274553,0.005840447,0.38070723],"study_design_scores_gemma":[0.39322713,0.043873,0.39186013,0.0022310906,0.0024178326,0.000006610382,0.0010825429,0.03248163,0.087319486,0.0066616656,0.037634555,0.0012043334],"about_ca_topic_score_codex":0.00010856683,"about_ca_topic_score_gemma":0.0000104557075,"teacher_disagreement_score":0.3795029,"about_ca_system_score_codex":0.00005625477,"about_ca_system_score_gemma":0.0022545063,"threshold_uncertainty_score":0.9163665},"labels":[],"label_agreement":null},{"id":"W4410414031","doi":"10.1186/s13195-025-01747-1","title":"Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer’s disease","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Neurological Disorders and Stroke; New York State Office of Mental Health; National Institute on Aging; National Institutes of Health; Alzheimer's Association","keywords":"Dentate gyrus; Neuroscience; Neurology; Medicine; Disease; Geriatric psychiatry; Hippocampus; Psychology; Psychiatry; Internal medicine","score_opus":0.12981159372828885,"score_gpt":0.41334780876684063,"score_spread":0.28353621503855175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410414031","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9156392,0.07822263,0.000012395598,0.001294563,0.000038906022,0.0035226522,0.00017381144,0.000023549572,0.0010722935],"genre_scores_gemma":[0.9951014,0.0037223506,0.00013334159,0.00032339807,0.000031049938,0.0005689475,0.000056607736,0.000041939205,0.000020962701],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99350387,0.0016183258,0.0009870562,0.0007400515,0.0020192557,0.0011314577],"domain_scores_gemma":[0.9959904,0.0010010358,0.00014370523,0.0015549411,0.00062316225,0.0006867341],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0030996252,0.0003770235,0.00083665573,0.001083076,0.00013737305,0.000046119087,0.00081038434,0.00015634068,0.00013466018],"category_scores_gemma":[0.0003443187,0.00026984047,0.000345588,0.0021968763,0.0010504819,0.00025478844,0.00020378528,0.0008632084,0.000031555814],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0275467,0.015302379,0.9048197,0.0003006243,0.020986553,0.0005293553,0.003958873,0.00042163298,0.0069700317,0.0013554279,0.0022096592,0.015599018],"study_design_scores_gemma":[0.01361261,0.0011290769,0.9496512,0.00043302157,0.000981637,0.0000018972614,0.0011039155,0.0054680114,0.02061331,0.0065285712,0.00010735159,0.0003693888],"about_ca_topic_score_codex":0.0076371785,"about_ca_topic_score_gemma":0.00017490672,"teacher_disagreement_score":0.07946221,"about_ca_system_score_codex":0.000101390484,"about_ca_system_score_gemma":0.0026914203,"threshold_uncertainty_score":0.9999754},"labels":[],"label_agreement":null},{"id":"W4410756404","doi":"10.1186/s13195-025-01760-4","title":"Research on the perspectives of people affected by dementia with Lewy bodies: a scoping review","year":2025,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Queen's University; Department for the Economy; Queen's University Belfast; Lewy Body Society","keywords":"Dementia with Lewy bodies; Bespoke; Dementia; Medicine; Population; Qualitative research; Psychology; Pathology; Disease; Sociology; Social science","score_opus":0.1926035335883169,"score_gpt":0.515260831445333,"score_spread":0.3226572978570161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410756404","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007189028,0.96644205,0.000008904943,0.002304434,0.000034433335,0.019710619,0.000056533743,0.000049995175,0.011321164],"genre_scores_gemma":[0.00043750033,0.9911814,0.00003196573,0.00021779427,0.00012241672,0.005793705,0.00015985037,0.0001233638,0.0019320499],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9834753,0.0076088295,0.0009153417,0.0013309543,0.004930542,0.0017390267],"domain_scores_gemma":[0.9875163,0.0066881636,0.0002589979,0.0018466334,0.0033520719,0.0003378752],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.012062194,0.0006915533,0.0027263865,0.0015432879,0.00078588945,0.00016423065,0.0013142594,0.00028584967,0.0026592365],"category_scores_gemma":[0.0011067665,0.00037069124,0.00068997184,0.0046969913,0.0013826789,0.00011983549,0.0004965488,0.0035151124,0.00021129899],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006807019,0.0021423576,0.00008043958,0.11455037,0.0138686225,0.000051709507,0.0009576534,1.848424e-8,0.000024968207,0.00037728372,0.0808211,0.7864448],"study_design_scores_gemma":[0.0013160026,0.0047336924,0.00008080652,0.6250538,0.0019001983,0.00002026682,0.0023262338,6.3534145e-7,0.0002457654,0.000029958319,0.363913,0.0003796536],"about_ca_topic_score_codex":0.0002854751,"about_ca_topic_score_gemma":0.000068667476,"teacher_disagreement_score":0.7860651,"about_ca_system_score_codex":0.00019951201,"about_ca_system_score_gemma":0.0047174287,"threshold_uncertainty_score":0.99987453},"labels":[],"label_agreement":null},{"id":"W4411450632","doi":"10.1186/s13195-025-01786-8","title":"Kidney function is associated with plasma ATN biomarkers among Hispanics/Latinos: SOL-INCA and HCHS/SOL results","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Minority Health and Health Disparities; National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases; University of Miami; National Institute on Deafness and Other Communication Disorders; Northwestern University; National Heart, Lung, and Blood Institute; National Institute on Aging; University of Illinois at Urbana-Champaign; Canadian Institutes of Health Research; San Diego State University; Office of Dietary Supplements; National Institutes of Health; National Institute of Environmental Health Sciences; Institut National Du Cancer","keywords":"Medicine; Renal function; Biomarker; Internal medicine; Cystatin C; Neurocognitive; Kidney disease; Gerontology; Prospective cohort study; Creatinine; Psychiatry; Cognition; Biology","score_opus":0.06293207835709619,"score_gpt":0.35460022173086037,"score_spread":0.2916681433737642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411450632","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9223855,0.04247493,0.000031986798,0.011429258,0.00020330395,0.004853865,0.0003253334,0.0003483469,0.017947467],"genre_scores_gemma":[0.99301726,0.003561611,0.00012454968,0.0009396319,0.000091757145,0.00030409923,0.00042125906,0.00008124571,0.001458603],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99483407,0.0006456812,0.00048058463,0.0010315317,0.0016877103,0.001320422],"domain_scores_gemma":[0.9961382,0.0007244574,0.0001303218,0.000894593,0.0009271756,0.0011852575],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014632469,0.00044199495,0.0005634403,0.00075538666,0.0007402187,0.0002013408,0.00027255685,0.0003005027,0.00029128275],"category_scores_gemma":[0.0005020269,0.0003288579,0.0001640766,0.0011229537,0.0008336188,0.00035448498,0.00016975579,0.0008286444,0.000105237785],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06850548,0.004018572,0.2900607,0.000107770924,0.25566605,0.0010994243,0.0020434798,0.0000025463048,0.0026027276,0.0002957346,0.27458352,0.101014],"study_design_scores_gemma":[0.09358773,0.016679505,0.7719867,0.0029297424,0.0060214545,0.00006497747,0.0018592881,0.0052981274,0.035012174,0.0020902473,0.06264441,0.0018256314],"about_ca_topic_score_codex":0.0010299608,"about_ca_topic_score_gemma":0.00017955812,"teacher_disagreement_score":0.48192602,"about_ca_system_score_codex":0.00021656453,"about_ca_system_score_gemma":0.0013740538,"threshold_uncertainty_score":0.9999164},"labels":[],"label_agreement":null},{"id":"W4412036054","doi":"10.1186/s13195-025-01789-5","title":"Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Beijing Institute of Technology; Beijing Nova Program; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China","keywords":"Biomarker; Neurology; Cerebrospinal fluid; Geriatric psychiatry; Medicine; Disease; Alzheimer's disease; Neuroscience; Bioinformatics; Pathology; Psychiatry; Psychology; Biology","score_opus":0.1633206353912723,"score_gpt":0.4033110003731224,"score_spread":0.23999036498185009,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412036054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.51429,0.23078087,0.18062949,0.019270277,0.00022690053,0.029964924,0.0013801962,0.0027157862,0.020741602],"genre_scores_gemma":[0.9819546,0.0006943716,0.0073154867,0.000100545425,0.0000634935,0.008148174,0.0002479432,0.00008156853,0.0013938529],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974845,0.00015214302,0.00044241836,0.0007296923,0.00041896652,0.0007722842],"domain_scores_gemma":[0.9984121,0.00027668136,0.00009033247,0.00072448375,0.00030973533,0.00018668141],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008306902,0.00029404002,0.00027628767,0.00033397315,0.0005072567,0.00019852984,0.00068457593,0.00016879004,0.00054234755],"category_scores_gemma":[0.000108119195,0.00028347436,0.00016826825,0.00070156675,0.00025590093,0.00017924192,0.0001298782,0.0007152944,0.000014670802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005531458,0.0014214796,0.006193274,0.0002841115,0.0011652586,0.00003683416,0.00014186521,0.0039299107,0.81391376,0.012932295,0.0027314497,0.1517183],"study_design_scores_gemma":[0.0039725513,0.00022695329,0.0018224026,0.00047511247,0.00012275693,0.0000011704037,0.0002186408,0.104371816,0.7734527,0.036408797,0.0780377,0.0008893814],"about_ca_topic_score_codex":0.0005346358,"about_ca_topic_score_gemma":0.00004194515,"teacher_disagreement_score":0.4676646,"about_ca_system_score_codex":0.000071910545,"about_ca_system_score_gemma":0.00040183094,"threshold_uncertainty_score":0.99996173},"labels":[],"label_agreement":null},{"id":"W4412042649","doi":"10.1186/s13195-025-01801-y","title":"Predicting brain amyloid load with digital and blood-based biomarkers","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Medicine; Montreal Cognitive Assessment; Biomarker; Disease; Neurology; Internal medicine; Cognitive impairment; Oncology; Psychiatry","score_opus":0.04379501370967498,"score_gpt":0.37073673139131624,"score_spread":0.32694171768164126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412042649","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9602395,0.0075057517,0.000116203104,0.009786736,0.000027213917,0.0015849081,0.000014954204,0.00009005367,0.02063467],"genre_scores_gemma":[0.9961977,0.00036462027,0.00015133065,0.000950525,0.00005932347,0.00018139664,0.0000258021,0.000031654636,0.002037664],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9969555,0.00021866288,0.00020652077,0.0005203243,0.0013299888,0.00076900603],"domain_scores_gemma":[0.99798435,0.0006330308,0.000028430815,0.0003783612,0.0006882629,0.0002875508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014663558,0.00019692157,0.00024282816,0.00048538708,0.0003029993,0.00027190207,0.00018171956,0.00008244153,0.0002368176],"category_scores_gemma":[0.00024224435,0.00014210044,0.00006777684,0.0010221095,0.00067115686,0.00019917288,0.00010200152,0.00048981665,0.000026724982],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0051120054,0.0008218668,0.7180988,0.000059893613,0.0040995805,0.0001375149,0.00018378977,3.0062156e-7,0.01892939,0.000092859234,0.004311633,0.24815236],"study_design_scores_gemma":[0.035346508,0.015881874,0.5701248,0.0012532776,0.00062622386,0.000091501664,0.0019834628,0.0013703193,0.2439535,0.0007530878,0.12784451,0.0007709404],"about_ca_topic_score_codex":0.00018860826,"about_ca_topic_score_gemma":0.000017364273,"teacher_disagreement_score":0.24738142,"about_ca_system_score_codex":0.000044156055,"about_ca_system_score_gemma":0.0009707433,"threshold_uncertainty_score":0.5794688},"labels":[],"label_agreement":null},{"id":"W4412354583","doi":"10.1186/s13195-025-01805-8","title":"Cerebral small vessel disease in memory center patients with dementia with lewy bodies and Alzheimer’s disease","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Intracerebral and Subarachnoid Hemorrhage Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Université de Lausanne","keywords":"Dementia with Lewy bodies; Geriatric psychiatry; Disease; Medicine; Neurology; Dementia; Center (category theory); Psychiatry; Pathology","score_opus":0.04922912525276848,"score_gpt":0.32965364557051385,"score_spread":0.2804245203177454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412354583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9468848,0.042119518,0.000024151606,0.006581145,0.000052418192,0.0026796795,0.000045183875,0.00006452895,0.0015485736],"genre_scores_gemma":[0.99606496,0.0012114005,0.0005928288,0.000729056,0.00008652953,0.00038517086,0.000138865,0.00006670162,0.00072447484],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9959909,0.00038747097,0.00034753577,0.0008358575,0.0012237029,0.0012145585],"domain_scores_gemma":[0.9975567,0.00018654342,0.000047413247,0.0007495264,0.0006321172,0.0008277215],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00067768677,0.00038449097,0.00045783026,0.0005846685,0.00037532678,0.0001537419,0.00033193734,0.00009552028,0.00028596935],"category_scores_gemma":[0.00007128608,0.00025220137,0.00008151533,0.00057556137,0.00076518493,0.00028508858,0.00021961404,0.0009374017,0.000035383444],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015320891,0.0015477863,0.8990621,0.00013210387,0.0015482478,0.00036846971,0.00045051824,0.000004900166,0.000048110276,0.00021531839,0.0013789996,0.079922535],"study_design_scores_gemma":[0.011847591,0.0009878849,0.98045486,0.00044246542,0.00042543348,0.000003032943,0.00025406745,0.0011502793,0.0007999567,0.00033871306,0.0029028559,0.00039285643],"about_ca_topic_score_codex":0.00040750034,"about_ca_topic_score_gemma":0.00020490555,"teacher_disagreement_score":0.08139274,"about_ca_system_score_codex":0.00006257503,"about_ca_system_score_gemma":0.00076754706,"threshold_uncertainty_score":0.999993},"labels":[],"label_agreement":null},{"id":"W4412549748","doi":"10.1186/s13195-025-01810-x","title":"A normative calculator for MoCA domain scores: proxy for Z-scores of conventional neuropsychological tests","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Medical Research Council; National Institute on Aging; National Institutes of Health","keywords":"Calculator; Normative; Neuropsychology; Neurology; Proxy (statistics); Psychology; Clinical psychology; Geriatric psychiatry; Medicine; Psychiatry; Cognition; Statistics; Computer science; Mathematics; Political science","score_opus":0.11356784709357642,"score_gpt":0.46672385945739936,"score_spread":0.35315601236382294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412549748","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96233857,0.0060818885,0.008142135,0.006749297,0.00016572517,0.012140232,0.0001665329,0.000060436432,0.004155169],"genre_scores_gemma":[0.9905459,0.0004277001,0.0027809823,0.0008777468,0.00013336439,0.0034696388,0.00012448401,0.000033291682,0.0016068436],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9970839,0.0003550321,0.00043584293,0.00048733645,0.0009014563,0.00073640153],"domain_scores_gemma":[0.99627304,0.0013599936,0.00007253951,0.00035473483,0.001749555,0.0001901351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019749175,0.00019267018,0.0003945805,0.00048831286,0.00025671718,0.000049412458,0.00031003242,0.00011468207,0.00030562293],"category_scores_gemma":[0.0005239265,0.0001421394,0.00030213632,0.00066294166,0.0006670406,0.00010759576,0.000093631716,0.00034544058,0.00001905766],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.08082746,0.010631359,0.3073909,0.0012785618,0.010951416,0.000069290225,0.0015278343,0.0000029619298,0.22225606,0.050543725,0.12318694,0.1913335],"study_design_scores_gemma":[0.034961917,0.019203307,0.6506287,0.00067812146,0.00030773372,0.00002496546,0.0009325681,0.00097434374,0.13123946,0.05026386,0.11031851,0.00046652718],"about_ca_topic_score_codex":0.00002507384,"about_ca_topic_score_gemma":0.0000046605896,"teacher_disagreement_score":0.3432378,"about_ca_system_score_codex":0.000037861246,"about_ca_system_score_gemma":0.0005249691,"threshold_uncertainty_score":0.57962763},"labels":[],"label_agreement":null},{"id":"W4413035771","doi":"10.1186/s13195-025-01827-2","title":"Longitudinal structural MRI-based deep learning and radiomics features for predicting Alzheimer’s disease progression","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Radiomics and Machine Learning in Medical Imaging","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Association","keywords":"Geriatric psychiatry; Neurology; Disease; Medicine; Radiomics; Artificial intelligence; Internal medicine; Psychiatry; Radiology; Computer science","score_opus":0.049660426728500795,"score_gpt":0.4247021297416508,"score_spread":0.37504170301315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413035771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5228315,0.410218,0.013387456,0.043501217,0.00094894675,0.0070521114,0.000025273193,0.00057856354,0.0014569584],"genre_scores_gemma":[0.9854775,0.001986508,0.010716073,0.0006478801,0.0004750692,0.0002792915,0.00013436752,0.00007542862,0.0002078785],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99704766,0.0003440739,0.0003368319,0.0006949791,0.0007495881,0.00082686427],"domain_scores_gemma":[0.99773467,0.00093462237,0.00009079773,0.0003495071,0.00037232556,0.00051809015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016621792,0.0002891925,0.0004180232,0.0004623698,0.0009468918,0.00020627449,0.00024354915,0.00014202973,0.000048645732],"category_scores_gemma":[0.00084716274,0.00022372579,0.00016539289,0.0004775508,0.0005462914,0.00012794862,0.000110444525,0.0014387793,0.0000020984412],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0041261883,0.0001317156,0.2859686,0.00012473977,0.0013534253,0.00007495496,0.00034713672,0.00034156765,0.0019324189,0.0007481004,0.0021512797,0.70269984],"study_design_scores_gemma":[0.0154201,0.0020122384,0.27296543,0.0012922502,0.0013464234,0.000074281,0.0004582075,0.5921223,0.005027451,0.0025680538,0.1059432,0.0007700759],"about_ca_topic_score_codex":0.00006457748,"about_ca_topic_score_gemma":0.0000043509554,"teacher_disagreement_score":0.7019298,"about_ca_system_score_codex":0.000052486375,"about_ca_system_score_gemma":0.00037457782,"threshold_uncertainty_score":0.9123273},"labels":[],"label_agreement":null},{"id":"W4413049854","doi":"10.1186/s13195-025-01815-6","title":"Machine learning applications in vascular neuroimaging for the diagnosis and prognosis of cognitive impairment and dementia: a systematic review and meta-analysis","year":2025,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; McGill University; Douglas Mental Health University Institute; Douglas College; Université de Montréal; Canada Research Chairs; Institut Universitaire de Gériatrie de Montréal","funders":"NIHR Cambridge Biomedical Research Centre; Trinity College, University of Cambridge; Fonds de Recherche du Québec - Santé; Courtois Foundation; Deutsches Zentrum für Neurodegenerative Erkrankungen; University of Toronto; Universitätsklinikum Köln; Marga und Walter Boll-Stiftung; National Institute for Health and Care Research; UK Research and Innovation; BrightFocus Foundation; Alzheimer Society; McGill University; Department of Health and Social Care; Joachim Herz Stiftung; Alzheimer's Association","keywords":"Dementia; Neuroimaging; Neurology; Meta-analysis; Vascular dementia; Medicine; Disease; Cognition; Cognitive decline; Neurochemistry; Alzheimer's disease; Internal medicine; Psychiatry; Psychology","score_opus":0.18560442812766637,"score_gpt":0.4629735725609544,"score_spread":0.27736914443328803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413049854","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000012129165,0.9669295,0.0001709518,0.00078751275,0.0000029931086,0.03195257,0.00010325655,0.000012464691,0.000028630631],"genre_scores_gemma":[0.0012245688,0.94566244,0.000062814936,0.00016468047,0.000008967575,0.05262428,0.00013650497,0.000038623464,0.00007709733],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9947984,0.0021248527,0.0009491955,0.0007882698,0.00081965583,0.00051961065],"domain_scores_gemma":[0.9911737,0.0072865556,0.00029502597,0.00043613516,0.00064660964,0.00016199882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0057328213,0.00043721945,0.004278683,0.0011062042,0.00032694975,0.000116640236,0.00024122246,0.00009940249,0.00009496159],"category_scores_gemma":[0.00063285785,0.00024078297,0.0011170625,0.002170689,0.00038138282,0.00007869657,0.0003104996,0.00074018445,0.0000010526786],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034439356,0.00041302535,0.0023639274,0.4585211,0.42590502,0.0000045764205,0.0001470195,5.4657527e-8,1.709242e-7,0.000030294472,0.000026444926,0.112553924],"study_design_scores_gemma":[0.00084593066,0.0005646764,0.0006153827,0.031239815,0.9503533,0.0000071299046,0.0002120288,0.00004939137,0.0000042802344,0.000027182161,0.015870577,0.0002102849],"about_ca_topic_score_codex":0.00016192305,"about_ca_topic_score_gemma":0.000021133912,"teacher_disagreement_score":0.52444834,"about_ca_system_score_codex":0.000024013547,"about_ca_system_score_gemma":0.0002096444,"threshold_uncertainty_score":0.9818845},"labels":[],"label_agreement":null},{"id":"W4413443612","doi":"10.1186/s13195-025-01825-4","title":"Metabolic syndrome and risk of incident all-cause dementia, Alzheimer’s disease and vascular dementia: a systematic review and meta-analysis of longitudinal studies","year":2025,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; University of Oxford","keywords":"Dementia; Medicine; Vascular dementia; Neurology; Disease; Geriatric psychiatry; Meta-analysis; Alzheimer's disease; Psychiatry; Internal medicine","score_opus":0.28178489167783616,"score_gpt":0.4834205222782704,"score_spread":0.20163563060043427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413443612","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00042840454,0.9875942,0.0000127563035,0.00017709339,0.000017315855,0.011444598,0.00028435746,0.000018215589,0.000023079121],"genre_scores_gemma":[0.0020451283,0.99420714,0.00009409186,0.000092588685,0.000012390312,0.0032791768,0.00012583706,0.00006381736,0.00007984251],"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","domain_scores_codex":[0.98835105,0.004825949,0.0021711953,0.0013009981,0.0025157393,0.000835072],"domain_scores_gemma":[0.9934108,0.0019265672,0.00097087177,0.0014703425,0.00159664,0.00062472356],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.008907451,0.000885101,0.012491218,0.0025081567,0.00024687214,0.00009292658,0.00047672668,0.00018412851,0.00034925478],"category_scores_gemma":[0.00088386156,0.00056005735,0.0025442487,0.002714265,0.001033029,0.0002276427,0.00094260665,0.00080199103,0.000005744489],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003799773,0.0002887919,0.0014791093,0.28561395,0.70352155,0.00006338131,0.00006575906,4.5077524e-8,3.796696e-7,0.0000496714,0.00007672056,0.008802621],"study_design_scores_gemma":[0.0007249647,0.00048630856,0.0033506574,0.025834186,0.9630124,0.000029685038,0.000097084514,0.0000034887137,0.000005287153,0.00004704771,0.0060630688,0.0003458278],"about_ca_topic_score_codex":0.00020895549,"about_ca_topic_score_gemma":0.000038384107,"teacher_disagreement_score":0.25977978,"about_ca_system_score_codex":0.000027678618,"about_ca_system_score_gemma":0.00050415524,"threshold_uncertainty_score":0.9996851},"labels":[],"label_agreement":null},{"id":"W4415381268","doi":"10.1186/s13195-025-01874-9","title":"Neurobiological correlates of Mild Behavioral Impairment: a systematic review and meta-analysis","year":2025,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Karolinska Institutet","keywords":"Neurology; Biomarker; Geriatric psychiatry; Neurochemistry; Neuroimaging; Neurogenetics; Brain aging","score_opus":0.33959279722110325,"score_gpt":0.5119813534569752,"score_spread":0.1723885562358719,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415381268","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000137814295,0.98547214,0.0000031141935,0.00029088336,0.000017840577,0.013658139,0.00015352089,0.0000343733,0.00035619346],"genre_scores_gemma":[0.00021725472,0.9927627,0.00003400337,0.00024253529,0.000015623606,0.0038002885,0.00028172386,0.000044791046,0.0026010736],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99092776,0.0042304527,0.0016017088,0.000983553,0.0014101487,0.00084639544],"domain_scores_gemma":[0.99538094,0.0016885152,0.00040800744,0.0012245366,0.0009502668,0.00034772232],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004594319,0.0006704871,0.010814568,0.0015808217,0.00016190842,0.0000749617,0.00062751677,0.00034944658,0.002272111],"category_scores_gemma":[0.00026744933,0.00036612997,0.004369886,0.0035353312,0.00055253925,0.00007355505,0.00040618793,0.0013484298,0.00006460891],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006657267,0.0008813908,0.000051040206,0.54547787,0.44137004,0.000055045395,0.00002724658,8.712994e-9,6.125269e-7,0.00002656787,0.0006475071,0.011396074],"study_design_scores_gemma":[0.00040463568,0.0018019151,0.000042271244,0.03715815,0.9440672,0.000041719108,0.000023038501,8.7744917e-7,0.0000052759456,0.000020997562,0.016173309,0.00026060946],"about_ca_topic_score_codex":0.00006605236,"about_ca_topic_score_gemma":0.0000031171157,"teacher_disagreement_score":0.50831974,"about_ca_system_score_codex":0.000047130277,"about_ca_system_score_gemma":0.0005726871,"threshold_uncertainty_score":0.99987906},"labels":[],"label_agreement":null},{"id":"W4415684328","doi":"10.1186/s13195-025-01844-1","title":"Sex differences in Alzheimer’s disease CSF biomarkers and their association with Aβ pathology on PET in cognitively unimpaired individuals","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; Occupational Cancer Research Centre; University of Toronto; University Health Network","funders":"HORIZON EUROPE European Research Council; H2020 Marie Skłodowska-Curie Actions; National Institute on Aging; Instituto de Salud Carlos III; NextGenerationEU; Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona; Agencia Estatal de Investigación; Ministerstvo Školství, Mládeže a Tělovýchovy; European Commission; Alzheimer's Association","keywords":"Association (psychology); Neurology; Disease; Geriatric psychiatry; Sex characteristics; Nonhuman primate","score_opus":0.07789521634913617,"score_gpt":0.3755480179030615,"score_spread":0.2976528015539254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415684328","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9783581,0.0071896217,0.000007921909,0.008697081,0.000032149692,0.0022569566,0.000049564027,0.000036257003,0.003372362],"genre_scores_gemma":[0.99519074,0.0028288376,0.000029174653,0.00091652555,0.000035240057,0.0005610868,0.00007280924,0.000027897606,0.0003377074],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9952104,0.0018050984,0.00034627222,0.0006955674,0.0009806,0.00096207997],"domain_scores_gemma":[0.99738395,0.0015652638,0.00007366846,0.00029389735,0.0003977562,0.00028548067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0032786883,0.0002940492,0.00050576206,0.0014642956,0.00017738806,0.000118326534,0.00022220908,0.00011995881,0.0001588121],"category_scores_gemma":[0.0003206142,0.00020542346,0.00006445687,0.001435726,0.0004390495,0.0001715697,0.00012772693,0.0007841368,0.0000202874],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003383516,0.0010506231,0.9033678,0.000014880631,0.0016560848,0.00030409137,0.0008813826,1.3482493e-7,0.000811444,0.00009332066,0.0005593692,0.08787735],"study_design_scores_gemma":[0.0070729246,0.0018251048,0.9815689,0.00032562407,0.00010167752,0.000006566465,0.002066731,0.00009934069,0.0049267993,0.001101195,0.0007088295,0.00019632306],"about_ca_topic_score_codex":0.00027285,"about_ca_topic_score_gemma":0.00012317767,"teacher_disagreement_score":0.087681025,"about_ca_system_score_codex":0.00012844065,"about_ca_system_score_gemma":0.0006298571,"threshold_uncertainty_score":0.83769256},"labels":[],"label_agreement":null},{"id":"W4416347601","doi":"10.1186/s13195-025-01895-4","title":"Drug repurposing for Alzheimer’s disease: a Delphi consensus and stakeholder consultation","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute on Aging; Department of Health and Social Care; National Institute for Health and Care Research; Alzheimer's Society; National Institutes of Health; Alzheimer's Drug Discovery Foundation","keywords":"Delphi method; Drug repositioning; Stakeholder; Repurposing; Delphi; Drug; Software deployment; Clinical trial","score_opus":0.18948267010332231,"score_gpt":0.44374965701052294,"score_spread":0.2542669869072006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416347601","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78186876,0.1786207,0.00043897526,0.024014486,0.00017160889,0.009148778,0.00007742589,0.00014404891,0.00551524],"genre_scores_gemma":[0.9895885,0.0042902725,0.00088012224,0.0012282713,0.00011032656,0.0010749922,0.00009873424,0.00004540151,0.0026833976],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99694824,0.0004141728,0.0003515715,0.00063309097,0.0008523089,0.00080062734],"domain_scores_gemma":[0.9962103,0.0014521407,0.000050390714,0.00042125778,0.0014670319,0.00039889768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002030834,0.00021881632,0.00031055402,0.0005491063,0.00053980463,0.00017953289,0.0001526047,0.00007571195,0.00016094798],"category_scores_gemma":[0.0005316798,0.00018637438,0.000107904845,0.00067606615,0.0006356264,0.00010496053,0.00009608607,0.0004017936,0.00002007257],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016137911,0.0012604134,0.047153726,0.00019166389,0.006169843,0.00014508737,0.0018594489,0.0000016050631,0.017120939,0.005195243,0.08256424,0.8221999],"study_design_scores_gemma":[0.040000472,0.0026576163,0.30174676,0.0011163653,0.002363407,0.00005301713,0.006480368,0.0028925682,0.081257075,0.014257984,0.54616964,0.0010047192],"about_ca_topic_score_codex":0.00012267494,"about_ca_topic_score_gemma":0.000015097194,"teacher_disagreement_score":0.8211952,"about_ca_system_score_codex":0.00004045083,"about_ca_system_score_gemma":0.000797343,"threshold_uncertainty_score":0.7600126},"labels":[],"label_agreement":null},{"id":"W4416985459","doi":"10.1186/s13195-025-01902-8","title":"Regional disparities of antidementia drug treatment in Germany: what can we learn for the new generation of Alzheimer’s therapies","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Impact","funders":"","keywords":"Drug treatment; Neurology; Drug; Pharmacotherapy; MEDLINE; Medical treatment; Alternative medicine","score_opus":0.17146976279829929,"score_gpt":0.42427760088205185,"score_spread":0.25280783808375257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416985459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.50902575,0.40372285,0.00023696257,0.0811125,0.00018924952,0.0052846665,0.000019255322,0.0000220052,0.00038676293],"genre_scores_gemma":[0.8889359,0.10659078,0.0001868435,0.0003828462,0.00014297763,0.00053863693,0.000053221316,0.000025639629,0.0031431508],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99741966,0.00035072086,0.00047664077,0.00035614794,0.0008481367,0.0005486984],"domain_scores_gemma":[0.9981755,0.0006116543,0.00009079299,0.0004576014,0.00056674297,0.00009773173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013949682,0.00020324065,0.00042030783,0.0005404104,0.00020164151,0.000089819485,0.00026059707,0.000070857284,0.00023140489],"category_scores_gemma":[0.000033604014,0.0001311819,0.00021604469,0.00061937264,0.00047743908,0.00021659171,0.000065751905,0.00023528875,0.0000033288363],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003143795,0.0017740348,0.039333455,0.00009622475,0.011187454,0.000008183763,0.0076107476,0.00001577357,0.075440794,0.0043808375,0.02839584,0.82861286],"study_design_scores_gemma":[0.01508996,0.0037459524,0.16899313,0.0007517041,0.0009843447,0.000005538768,0.010721039,0.0013298984,0.62721604,0.005331473,0.16547178,0.00035912902],"about_ca_topic_score_codex":0.002924981,"about_ca_topic_score_gemma":0.0008199736,"teacher_disagreement_score":0.82825375,"about_ca_system_score_codex":0.000054283566,"about_ca_system_score_gemma":0.0009182108,"threshold_uncertainty_score":0.5349443},"labels":[],"label_agreement":null},{"id":"W4417027810","doi":"10.1186/s13195-025-01924-2","title":"Post-infection brain atrophy accelerates cognitive and molecular changes underlying dementia","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Institute on Aging; Wellcome Trust","keywords":"Dementia; Atrophy; Neurocognitive; Neuroimaging; Cognitive decline; Brain size; Biomarker; Cognition","score_opus":0.11129122338574791,"score_gpt":0.4380348622182455,"score_spread":0.3267436388324976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417027810","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94280183,0.031929906,0.00056754507,0.017213657,0.000070575305,0.00202014,0.00000856099,0.00007477619,0.0053130193],"genre_scores_gemma":[0.98953474,0.005792096,0.00008674689,0.0033716238,0.000060068327,0.0003555168,0.000058701917,0.000033237477,0.00070725963],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99718845,0.00054464885,0.00018808593,0.00053840445,0.000791297,0.00074913073],"domain_scores_gemma":[0.99794185,0.00046565273,0.000032810556,0.00022882572,0.0011196828,0.00021118026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012569001,0.0002138366,0.00026244365,0.00078179454,0.00043994663,0.00021985269,0.00011572848,0.000111333626,0.00053358555],"category_scores_gemma":[0.0002064947,0.00018416268,0.00008715765,0.00087139005,0.00036690047,0.00016279667,0.00017243472,0.0005521699,0.000060808346],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016474099,0.00047380332,0.071052864,0.00007033317,0.0049329265,0.000099965466,0.00040773675,1.14555164e-7,0.3419039,0.000721595,0.0013685249,0.5773208],"study_design_scores_gemma":[0.00860362,0.0053705154,0.5193157,0.00041910852,0.0005624642,0.000030822826,0.0015305106,0.00013030176,0.4390968,0.0023282329,0.022217441,0.00039446226],"about_ca_topic_score_codex":0.00046726287,"about_ca_topic_score_gemma":0.000062630446,"teacher_disagreement_score":0.57692635,"about_ca_system_score_codex":0.000039111324,"about_ca_system_score_gemma":0.00026084532,"threshold_uncertainty_score":0.7509936},"labels":[],"label_agreement":null},{"id":"W4417070016","doi":"10.1186/s13195-025-01908-2","title":"International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"EU Joint Programme – Neurodegenerative Disease Research; National Institute on Aging; Agence Nationale de la Recherche; Alzheimer's Association","keywords":"Neurocognitive; Relevance (law); Set (abstract data type); Signature (topology); Cognition; MEDLINE","score_opus":0.27310158638915527,"score_gpt":0.5352274964617199,"score_spread":0.2621259100725646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417070016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.519817,0.002992939,0.008649983,0.44003952,0.00092888717,0.009414837,0.0005032689,0.00003284926,0.017620744],"genre_scores_gemma":[0.9959041,0.0019012142,0.00090418855,0.00092405605,0.000049898525,0.00023781382,0.00004563053,0.0000113525875,0.000021746318],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99817586,0.0007291942,0.00037809816,0.00020737786,0.0003579777,0.00015151392],"domain_scores_gemma":[0.99206865,0.0068543656,0.0001536664,0.00014780097,0.0007554242,0.000020079227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011816628,0.000089360394,0.00020889897,0.00018122046,0.00020070618,0.000017566093,0.00013128083,0.00013666898,0.00007217664],"category_scores_gemma":[0.0011673118,0.00005979114,0.0001356454,0.000461057,0.00058451534,0.000059576552,0.00007639097,0.0008096322,6.2484435e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0060186503,0.00807598,0.18139407,0.00013511578,0.010139985,0.000003308279,0.006203342,0.000014106898,0.0037732818,0.11043811,0.012360553,0.6614435],"study_design_scores_gemma":[0.0067812847,0.00060848356,0.92774403,0.0003627178,0.00039971605,0.0000023933985,0.014589589,0.0013668829,0.0004550889,0.036081336,0.011484889,0.00012359042],"about_ca_topic_score_codex":0.000023828281,"about_ca_topic_score_gemma":0.000052538184,"teacher_disagreement_score":0.74635,"about_ca_system_score_codex":0.000021113401,"about_ca_system_score_gemma":0.00025897927,"threshold_uncertainty_score":0.3517494},"labels":[],"label_agreement":null},{"id":"W4417517383","doi":"10.1186/s13195-025-01929-x","title":"Comparative dementia risk with GLP1 receptor agonists, SGLT2 inhibitors, or DPP4 inhibitors: a population-based cohort study","year":2025,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; University of Ottawa; Toronto General Hospital; University of Toronto; University Health Network; Canada Research Chairs; Toronto Rehabilitation Institute; University of Waterloo; Sunnybrook Health Science Centre","funders":"Temerty Faculty of Medicine, University of Toronto; Canadian Institutes of Health Research; Novo Nordisk; University of Toronto; Canada Excellence Research Chairs, Government of Canada; Canada Research Chairs; Ministry of Colleges and Universities; Alzheimer's Drug Discovery Foundation","keywords":"Dementia; Cohort study; Diabetes mellitus; Cohort; Confidence interval; Type 2 diabetes; Type 2 Diabetes Mellitus; Lower risk","score_opus":0.07011970409647994,"score_gpt":0.39070530839593015,"score_spread":0.3205856042994502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417517383","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9772911,0.007215621,0.000043108783,0.0016524837,0.00025385796,0.0096462825,0.000021922022,0.00019436485,0.0036812355],"genre_scores_gemma":[0.9939753,0.00045020823,0.0007806534,0.00029976302,0.00019936195,0.0015593624,0.00029626006,0.000047536403,0.0023915526],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9959117,0.0007162005,0.0004884495,0.00079414516,0.0013583818,0.0007311171],"domain_scores_gemma":[0.9978673,0.00040453955,0.00013730393,0.0008491004,0.0005120483,0.00022972703],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014714922,0.0003892643,0.0006896868,0.0006505282,0.0005565698,0.0001868253,0.0002606971,0.00009534524,0.00064097013],"category_scores_gemma":[0.00005176958,0.00025546813,0.00012676751,0.0014898346,0.00021081294,0.00017570137,0.00010616729,0.0005072273,0.0001734578],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003774598,0.0036663369,0.89561296,0.00002291807,0.014382098,0.000039392828,0.00068030116,0.000017342285,0.00018475548,0.00006386155,0.06490802,0.016647398],"study_design_scores_gemma":[0.017997598,0.0103937555,0.80566275,0.0004267419,0.0027028546,8.2362556e-7,0.0023713096,0.00029100644,0.013195934,0.00007474812,0.14630954,0.000572928],"about_ca_topic_score_codex":0.0023479355,"about_ca_topic_score_gemma":0.000607972,"teacher_disagreement_score":0.08995021,"about_ca_system_score_codex":0.00020909878,"about_ca_system_score_gemma":0.00044495796,"threshold_uncertainty_score":0.99998975},"labels":[],"label_agreement":null}]}