{"meta":{"query_hash":"71224093593c","filters":{"venue":"Biologicals"},"cohort_total":83,"direct_labels_cover":0,"predictions_cover":83,"exported":83,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/71224093593c","api":"https://metacan.xera.ac/api/v1/cohort?venue=Biologicals"},"results":[{"id":"W1177880600","doi":"10.1016/j.biologicals.2015.07.009","title":"Report of the international conference on regulatory endeavors towards the sound development of human cell therapy products","year":2015,"lang":"en","type":"article","venue":"Biologicals","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Medical Research Council; National Institute of Biomedical Innovation; Ministry of Health, Labour and Welfare; Japan Science and Technology Agency; World Health Organization","keywords":"Risk analysis (engineering); Process (computing); Business; Engineering ethics; Management science; Process management; Computer science; Engineering","score_opus":0.2645227128454013,"score_gpt":0.36872885893575885,"score_spread":0.10420614609035755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1177880600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98005354,0.00013179617,0.000025106716,0.011025478,0.00026911445,0.00025690327,0.0000020683372,0.000009487617,0.008226486],"genre_scores_gemma":[0.99835,0.000021603215,0.00033903564,0.00029401382,0.00009186486,0.0000072339703,0.000017427146,0.0000028993713,0.0008759057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989607,0.000060307753,0.00032251785,0.00014746841,0.00043629343,0.000072761046],"domain_scores_gemma":[0.99910975,0.00002522973,0.00023672615,0.0002730346,0.00031556806,0.000039674487],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001169576,0.000068060064,0.00014448684,0.000020614028,0.000044386183,0.0000037503407,0.00018447441,0.00012688963,0.000058210975],"category_scores_gemma":[0.00017996712,0.000025237296,0.00004364911,0.0000798083,0.000632807,0.0000076064357,0.0000643169,0.00012789894,0.0000016156937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037802395,0.0011687779,0.012939811,0.0000899261,0.00020495459,0.000012861919,0.0038909959,0.0000049356527,0.8722195,0.06618821,0.0041235615,0.03877846],"study_design_scores_gemma":[0.001048099,0.00058177713,0.43770346,0.00011679919,0.000015836575,0.000028693712,0.00043904563,0.000022493095,0.507509,0.02047594,0.031941682,0.00011719984],"about_ca_topic_score_codex":0.0000077638615,"about_ca_topic_score_gemma":0.0000015657325,"teacher_disagreement_score":0.42476365,"about_ca_system_score_codex":0.000029781737,"about_ca_system_score_gemma":0.00033095683,"threshold_uncertainty_score":0.23316036},"labels":[],"label_agreement":null},{"id":"W1966368702","doi":"10.1016/j.biologicals.2006.03.001","title":"Regulation and standardization of IPV and IPV combination vaccines","year":2006,"lang":"en","type":"article","venue":"Biologicals","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Standardization; Immunogenicity; Potency; In vivo; In vitro toxicology; Medicine; Biology; Biotechnology; Antigen; Immunology; In vitro; Computer science","score_opus":0.019687646091801386,"score_gpt":0.30678527869203787,"score_spread":0.28709763260023646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966368702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954908,0.0010449353,0.0015710497,0.0005896484,0.000018239663,0.00016018921,0.0000039400984,0.00001841657,0.0011027995],"genre_scores_gemma":[0.9989129,0.00036171655,0.00024125146,0.000017305627,0.000021801452,0.000004872603,0.00004053018,0.0000019727593,0.00039768987],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99964976,0.000039049148,0.000121159836,0.00008872682,0.000042620326,0.000058678368],"domain_scores_gemma":[0.9997515,0.000036792993,0.000039316667,0.00005463293,0.000104973806,0.000012772442],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016313273,0.000039319868,0.00011526867,0.000058978978,0.000047820708,0.000006082023,0.000009465956,0.00007871544,0.000046660552],"category_scores_gemma":[0.000095475516,0.000025969144,0.00001233143,0.00009052095,0.000083729916,0.000038104594,0.000017172768,0.00003664649,0.0000010830039],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018040687,0.00015734392,0.5196187,0.000042696003,0.000023984996,9.054035e-7,0.00001587371,0.000008972504,0.44712657,0.013827489,0.0006526868,0.018344399],"study_design_scores_gemma":[0.00061973033,0.0005984914,0.97811407,0.000014175434,0.000010798236,0.000009967541,0.000010997723,0.000145903,0.014770099,0.0038211956,0.0018549971,0.000029580897],"about_ca_topic_score_codex":0.00003338506,"about_ca_topic_score_gemma":0.0000026910404,"teacher_disagreement_score":0.45849538,"about_ca_system_score_codex":0.000008832129,"about_ca_system_score_gemma":0.000006406918,"threshold_uncertainty_score":0.105899096},"labels":[],"label_agreement":null},{"id":"W1968444923","doi":"10.1016/j.biologicals.2010.07.005","title":"Excipient exchange in the comparison of preparations of the same biologic made by different manufacturing processes: An exploratory study with recombinant human growth hormone (rhGH)","year":2010,"lang":"en","type":"article","venue":"Biologicals","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Excipient; Chemistry; Innovator; Drug; Human growth hormone; Mannitol; Pharmacology; Chromatography; Biochemical engineering; Biochemistry; Hormone; Growth hormone; Medicine; Business; Entrepreneurship; Engineering","score_opus":0.03874264423928938,"score_gpt":0.30944956827301373,"score_spread":0.27070692403372437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968444923","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99812174,0.00048572724,0.000057820438,0.00011682978,0.000033436187,0.0010941306,0.000032327876,0.000008362521,0.00004961637],"genre_scores_gemma":[0.9994163,0.00005600346,0.000043536133,0.00003892286,0.000018425517,0.00033335856,0.000070711,0.0000049018477,0.000017852662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860835,0.0004282745,0.00036212758,0.00033122397,0.00011650425,0.00015349397],"domain_scores_gemma":[0.99903536,0.00003713425,0.0002506869,0.00056376006,0.0000797533,0.000033328433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051116827,0.00014619513,0.00023110874,0.000021140298,0.000105723615,0.00001112626,0.0005051359,0.00013074398,0.000012600519],"category_scores_gemma":[0.00012632067,0.00006330024,0.000042361677,0.00009650319,0.00025408427,0.0000053643835,0.00010623214,0.00015813022,3.822431e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011241859,0.0025979627,0.116526924,0.00002739014,0.00001748847,1.5080566e-7,0.0011412777,0.0000018212188,0.879198,0.00008048001,0.00007128664,0.00022477307],"study_design_scores_gemma":[0.0004714945,0.0031672425,0.42825687,0.000007458756,0.000012274977,9.961258e-7,0.0027819348,0.000002691169,0.56428313,0.00034825143,0.00053231645,0.00013534885],"about_ca_topic_score_codex":0.000022431605,"about_ca_topic_score_gemma":0.0005672409,"teacher_disagreement_score":0.31491488,"about_ca_system_score_codex":0.000006995208,"about_ca_system_score_gemma":0.000023303503,"threshold_uncertainty_score":0.2581309},"labels":[],"label_agreement":null},{"id":"W1980282196","doi":"10.1016/j.biologicals.2014.05.005","title":"The challenge of indication extrapolation for infliximab biosimilars","year":2014,"lang":"en","type":"review","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":148,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Western University; University of British Columbia; University of Toronto; University of Calgary; University of Alberta; Robarts Clinical Trials; Université de Montréal","funders":"Genentech; Celltrion; UCB; LEO Pharma; Ironwood Pharmaceuticals, Incorporated; Teva Pharmaceutical Industries; Gilead Sciences; ActoGeniX; Sanofi; Celgene; Biogen; GlaxoSmithKline; Amgen; Pfizer; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Biosimilar; Infliximab; Medicine; Extrapolation; Pharmacology; Internal medicine; Mathematics; Tumor necrosis factor alpha; Statistics","score_opus":0.12163158240022143,"score_gpt":0.40752275257993253,"score_spread":0.2858911701797111,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980282196","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000012922433,0.99617213,0.00088377466,0.00052941893,0.0004332872,0.0011345648,0.0001831884,0.000035573714,0.00062676024],"genre_scores_gemma":[0.00011997245,0.9983253,0.00053668214,0.000094341995,0.00009106662,0.0002471995,0.0002372153,0.000016566817,0.00033167427],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973971,0.0008431506,0.0009626529,0.00042167632,0.00003289187,0.00034253317],"domain_scores_gemma":[0.99545014,0.0030761044,0.00089535007,0.00046070744,0.000095092415,0.00002260678],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0017466575,0.00032132806,0.0014480674,0.00008839345,0.00021123138,0.000013695041,0.000533536,0.0014928888,0.00012151113],"category_scores_gemma":[0.0010773212,0.00014717988,0.00069938006,0.0001698857,0.00054440927,0.000016079512,0.00009476535,0.0003179532,0.00003960123],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023205384,0.000054786815,0.0000016639374,0.0011046545,0.0002285342,5.5787016e-8,0.000004619934,1.0918239e-8,0.00008380033,0.008323904,0.0019661237,0.98820865],"study_design_scores_gemma":[0.00019472672,0.00039567612,0.000011722463,0.00069384306,0.00040581397,0.000003296011,0.0000037477444,0.0000011443503,0.00011254522,0.0024663971,0.99551564,0.00019545537],"about_ca_topic_score_codex":7.2404833e-7,"about_ca_topic_score_gemma":0.0000011420452,"teacher_disagreement_score":0.9935495,"about_ca_system_score_codex":0.0000271287,"about_ca_system_score_gemma":0.000057883477,"threshold_uncertainty_score":0.99980336},"labels":[],"label_agreement":null},{"id":"W1980971590","doi":"10.1016/j.biologicals.2011.08.001","title":"Risk perception, risk management and safety assessment: What can governments do to increase public confidence in their vaccine system?","year":2011,"lang":"en","type":"article","venue":"Biologicals","topic":"Vaccine Coverage and Hesitancy","field":"Social Sciences","cited_by":93,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Risk perception; Vaccination; Vaccine safety; Public health; Perception; Risk management; Public trust; Medicine; Business; Public relations; Environmental health; Risk analysis (engineering); Immunization; Immunology; Psychology; Political science; Finance; Nursing","score_opus":0.03256947408089026,"score_gpt":0.2852710269424206,"score_spread":0.25270155286153034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980971590","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97783893,0.00062833005,0.00035730502,0.0004666288,0.00014284994,0.0007516841,0.00005194118,0.000066536806,0.019695796],"genre_scores_gemma":[0.98254484,0.016156109,0.0005885497,0.0003199905,0.00007706173,0.000068105604,0.0000055456494,0.000005804644,0.00023400571],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9978768,0.0007762144,0.0003287604,0.00042853635,0.000215774,0.00037390593],"domain_scores_gemma":[0.99915487,0.00013589162,0.00016887095,0.00024999364,0.000059339032,0.00023102734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017945768,0.0001577872,0.0002639323,0.00007261553,0.00042077713,0.0001859799,0.00031660128,0.00011649828,0.00064051227],"category_scores_gemma":[0.00020830255,0.00011119455,0.00004630336,0.00026537204,0.000022523947,0.00034716754,0.00018987562,0.00013151135,0.00004435656],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053045365,0.00008814604,0.94757134,0.000014209193,0.000030120513,0.000016848682,0.003498954,4.4069046e-7,0.000019188106,0.022746509,0.00030596645,0.025655262],"study_design_scores_gemma":[0.00041058136,0.000109607514,0.9595402,0.000079363315,0.000018655479,9.1599475e-7,0.031171702,0.0000047891144,0.0000026399468,0.0017794964,0.0067192903,0.00016278557],"about_ca_topic_score_codex":0.0050624525,"about_ca_topic_score_gemma":0.003868769,"teacher_disagreement_score":0.027672749,"about_ca_system_score_codex":0.0003266237,"about_ca_system_score_gemma":0.000033124943,"threshold_uncertainty_score":0.7652948},"labels":[],"label_agreement":null},{"id":"W1983451228","doi":"10.1016/j.biologicals.2013.05.004","title":"Isolation of scFv antibody fragments against HER2 and CEA tumor antigens from combinatorial antibody libraries derived from cancer patients","year":2013,"lang":"en","type":"article","venue":"Biologicals","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Carleton University","funders":"","keywords":"Panning (audio); Antibody; Antigen; Molecular biology; Cancer research; Chemistry; Immunology; Biology","score_opus":0.02406813940690559,"score_gpt":0.311601789880519,"score_spread":0.2875336504736134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983451228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99553144,0.0015448417,0.000033076067,0.00044024008,0.00037321195,0.00065056066,0.0006353704,0.000040465773,0.00075079006],"genre_scores_gemma":[0.994984,0.0013280757,0.0009314251,0.0005182832,0.00029753835,0.00002449139,0.001807139,0.000015318348,0.00009376126],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983237,0.00013846197,0.00044605444,0.00042405614,0.00032637393,0.00034139262],"domain_scores_gemma":[0.9989016,0.00029454022,0.00018979004,0.00019255395,0.00020803478,0.0002134649],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007794468,0.00023428816,0.00058003026,0.000066887034,0.00012545068,0.0000497502,0.00015006028,0.000181578,0.0013955863],"category_scores_gemma":[0.00016823702,0.00015333951,0.000094865216,0.00013200809,0.00033166242,0.00017064813,0.00020519918,0.00018729751,0.0000633395],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025550512,0.00023470167,0.6160878,0.000022588249,0.000102043094,0.0000058707606,0.00007219647,2.7839488e-7,0.38179106,0.00006804929,0.00027183752,0.0010880758],"study_design_scores_gemma":[0.001656198,0.0005113917,0.96302575,0.00015489287,0.000030937266,3.6739598e-7,0.000057120076,0.00021451944,0.031190297,0.0015462929,0.0014311048,0.0001811184],"about_ca_topic_score_codex":0.0038038832,"about_ca_topic_score_gemma":0.000006855357,"teacher_disagreement_score":0.35060075,"about_ca_system_score_codex":0.000020365796,"about_ca_system_score_gemma":0.000060076934,"threshold_uncertainty_score":0.99951726},"labels":[],"label_agreement":null},{"id":"W1984123774","doi":"10.1016/j.biologicals.2009.12.004","title":"Application of deglycosylation and electrophoresis to the quantification of influenza viral hemagglutinins facilitating the production of 2009 pandemic influenza (H1N1) vaccines at multiple manufacturing sites in China","year":2010,"lang":"en","type":"article","venue":"Biologicals","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Radial immunodiffusion; Pandemic; Influenza vaccine; Hemagglutinin (influenza); Virology; Vaccination; Microbiology; Medicine; Biology; Coronavirus disease 2019 (COVID-19); Virus; Immunology; Antibody","score_opus":0.06461755601141886,"score_gpt":0.3600427258518038,"score_spread":0.2954251698403849,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984123774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973776,0.00083037955,0.00009157814,0.0003422957,0.000023301993,0.0012751257,0.000023489487,0.000018513716,0.000017762606],"genre_scores_gemma":[0.99899507,0.00014487808,0.00059067534,0.00006922,0.00004802766,0.00012388395,0.0000114528075,0.0000063266853,0.000010482146],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985567,0.00014053116,0.0006126767,0.00027569788,0.00021310919,0.0002013406],"domain_scores_gemma":[0.99841934,0.00064875314,0.00034185615,0.00036140825,0.00019635695,0.000032252312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011971414,0.0001323026,0.00031680067,0.00013314193,0.00011967021,0.000005068788,0.00013537495,0.0001063823,0.0000071922177],"category_scores_gemma":[0.0053250603,0.000068429894,0.000051569634,0.00027310304,0.00019673805,0.00005680492,0.00011655701,0.00021938878,0.0000034898062],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003555954,0.000034192864,0.43137205,0.0000579387,0.000014355248,3.7169354e-8,0.0004639132,0.00020126541,0.5624613,0.00003179852,0.000013304206,0.0049942546],"study_design_scores_gemma":[0.00023797322,0.00016457654,0.6773928,0.000026032489,0.000013503625,0.0000018350404,0.00013173789,0.00034797686,0.3211386,0.000086494925,0.00041215032,0.000046368197],"about_ca_topic_score_codex":0.00030542887,"about_ca_topic_score_gemma":0.0004366562,"teacher_disagreement_score":0.2460207,"about_ca_system_score_codex":0.000034541925,"about_ca_system_score_gemma":0.000020755462,"threshold_uncertainty_score":0.63749796},"labels":[],"label_agreement":null},{"id":"W1985803217","doi":"10.1016/j.biologicals.2006.05.001","title":"Potency assays for therapeutic live whole cell cancer vaccines","year":2006,"lang":"en","type":"review","venue":"Biologicals","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Clinical trial; Medicine; Cancer vaccine; Disease; Immune system; Infectious disease (medical specialty); Cancer; Vaccine efficacy; Potency; Immunology; Computational biology; Biology; Immunotherapy; Bioinformatics; In vitro","score_opus":0.06482583058028692,"score_gpt":0.343256172539,"score_spread":0.2784303419587131,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985803217","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000036745445,0.9949912,0.00010751526,0.0000895938,0.0013614321,0.0017937175,0.00086496194,0.00015202073,0.00060283433],"genre_scores_gemma":[0.00006220085,0.95356864,0.000055899625,0.00021062687,0.0001854883,0.0012864502,0.0012870139,0.00006652428,0.04327717],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99664867,0.0009527975,0.0009027815,0.000706073,0.000030621035,0.00075906474],"domain_scores_gemma":[0.99734426,0.0013586906,0.0006303496,0.0005366043,0.000111438574,0.000018641806],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00046280187,0.00075274997,0.0022984606,0.00016412332,0.00032896321,0.000035831752,0.00073449936,0.0017695208,0.0015037387],"category_scores_gemma":[0.00007229995,0.00044578288,0.0011758027,0.0001882357,0.00018715703,0.00004745935,0.000103702376,0.00051035674,0.0013198497],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001543116,0.00024801638,0.0000061686987,0.001623882,0.00058730517,0.0000023967639,0.000021954902,2.8610071e-7,0.005745717,0.000116786054,0.014819474,0.9766737],"study_design_scores_gemma":[0.00066328346,0.00052152097,0.00003338872,0.0011712791,0.0006003953,0.000028513101,0.000018096935,9.328447e-8,0.00053325784,0.0001577787,0.9956491,0.0006232956],"about_ca_topic_score_codex":0.00013095287,"about_ca_topic_score_gemma":0.0000057727066,"teacher_disagreement_score":0.9808296,"about_ca_system_score_codex":0.000087837994,"about_ca_system_score_gemma":0.00028141824,"threshold_uncertainty_score":0.9997994},"labels":[],"label_agreement":null},{"id":"W1987479544","doi":"10.1016/j.biologicals.2011.06.003","title":"The first subsequent entry biologic authorized for market in Canada: The story of Omnitrope, a recombinant human growth hormone","year":2011,"lang":"en","type":"review","venue":"Biologicals","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Health Canada","funders":"","keywords":"Human growth hormone; Guideline; Growth hormone; Product (mathematics); Business; Marketing; Political science; Medicine; Law; Hormone","score_opus":0.10752993073193548,"score_gpt":0.32914068602130137,"score_spread":0.22161075528936588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987479544","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019885547,0.99349797,0.000008367071,0.0028693033,0.00044522012,0.0024121557,0.000077554825,0.000015249095,0.00047532658],"genre_scores_gemma":[0.0048511783,0.99357873,0.000047307036,0.00016482927,0.00014112049,0.00046345944,0.00017579767,0.000018583383,0.00055900303],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972422,0.00079161953,0.00096436654,0.0003926482,0.00019233204,0.0004168334],"domain_scores_gemma":[0.9967933,0.0018500137,0.0006741914,0.00043018544,0.00014207803,0.0001102078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003405839,0.00033262256,0.0015368818,0.000071097216,0.00032116476,0.000008072359,0.0004697647,0.00075926713,0.00006638074],"category_scores_gemma":[0.0008882748,0.00011462997,0.0004061904,0.00028135424,0.0009541643,0.000008340316,0.00013180668,0.00089814473,0.0000020122793],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045331192,0.00034126214,0.00016023307,0.007378581,0.00054220285,0.00002959826,0.000055015174,1.5736552e-8,0.000039613675,0.030024946,0.038278196,0.922697],"study_design_scores_gemma":[0.0005684506,0.00055388466,0.004568117,0.0020167043,0.0002535199,0.000013992037,0.000033964574,0.0000028117727,0.0000014308041,0.0021710529,0.9896428,0.0001732754],"about_ca_topic_score_codex":0.035015624,"about_ca_topic_score_gemma":0.047717452,"teacher_disagreement_score":0.9513646,"about_ca_system_score_codex":0.00044728915,"about_ca_system_score_gemma":0.0013204276,"threshold_uncertainty_score":0.9714103},"labels":[],"label_agreement":null},{"id":"W1989847611","doi":"10.1016/j.biologicals.2011.06.015","title":"Quality, safety and efficacy of follow-on biologics in Japan","year":2011,"lang":"en","type":"review","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biosimilar; Comparability; Harmonization; Medicine; Quality (philosophy); Product (mathematics); Scientific evidence; Drug approval; Pharmacovigilance; Risk analysis (engineering); Business; Pharmacology; Adverse effect; Internal medicine; Drug","score_opus":0.22196667777815177,"score_gpt":0.4229495287818701,"score_spread":0.20098285100371832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989847611","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00047562938,0.99441075,0.00001003626,0.000031395084,0.00029449837,0.00064091134,0.00025505078,0.000037520884,0.0038441902],"genre_scores_gemma":[0.00066410884,0.99814415,0.00032627606,0.00013404344,0.000028395412,0.000019573601,0.00012210128,0.000014413639,0.0005469318],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9952464,0.002139224,0.0014135707,0.00072245,0.00002590793,0.0004524097],"domain_scores_gemma":[0.9961551,0.0027457264,0.0005660819,0.0004567117,0.00003368955,0.00004271639],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001913332,0.0005062629,0.0032135702,0.0001986637,0.000053765507,0.0000058208243,0.00046625253,0.0022920263,0.00061411096],"category_scores_gemma":[0.0014156954,0.0002660542,0.000562725,0.00030059417,0.0007862872,0.000012663361,0.00031788525,0.000703184,0.00009599307],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018488857,0.00028423735,0.00029250872,0.0008123011,0.00020333363,0.0000021310655,0.000011043973,7.4300686e-9,0.000115445604,0.012224985,0.00011336904,0.98575574],"study_design_scores_gemma":[0.00064456335,0.00089212187,0.003185656,0.0017088626,0.00017364103,0.000014802055,0.000010241717,2.2480947e-8,0.000051220162,0.00055883796,0.99236566,0.00039437177],"about_ca_topic_score_codex":0.000026724521,"about_ca_topic_score_gemma":0.0000052352852,"teacher_disagreement_score":0.9922523,"about_ca_system_score_codex":0.000032025888,"about_ca_system_score_gemma":0.000047235204,"threshold_uncertainty_score":0.99997914},"labels":[],"label_agreement":null},{"id":"W2002321378","doi":"10.1016/j.biologicals.2009.01.004","title":"Role of regulatory agencies","year":2009,"lang":"en","type":"review","venue":"Biologicals","topic":"Blood donation and transfusion practices","field":"Business, Management and Accounting","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Regulatory authority; Perspective (graphical); Business; Risk analysis (engineering); Quality (philosophy); Political science; Computer science; Public administration","score_opus":0.077021149111106,"score_gpt":0.3085727936760933,"score_spread":0.2315516445649873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002321378","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003219765,0.9328098,0.0000017473535,0.000041168598,0.000094504954,0.00025644674,0.0000051822567,0.00008418026,0.06667472],"genre_scores_gemma":[0.00034478298,0.9983587,0.00007632631,0.00042133572,0.0004153665,0.000017405951,0.00005345705,0.000010213782,0.00030236365],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998959,0.0000342829,0.00047346271,0.0002506525,0.00014374316,0.00013884917],"domain_scores_gemma":[0.99894196,0.000121126766,0.0006334843,0.00021709203,0.00007882018,0.000007526732],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00039752063,0.00021320126,0.00084796,0.00018805843,0.000058762675,0.00006121066,0.00030106222,0.00028134097,0.0010846369],"category_scores_gemma":[0.00018049832,0.00013058727,0.00032991302,0.00033742905,0.000060147137,0.00024174433,0.00006816332,0.00014193564,0.0004281766],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000018956999,0.000046555706,0.000004790869,0.001339924,0.000029968138,0.0000012405303,0.0000013309833,6.039398e-8,0.000006508732,0.02781429,0.00060123805,0.9701522],"study_design_scores_gemma":[0.000048387334,0.000008078582,0.0001069129,0.000833851,0.00026684385,0.0000014995053,0.000018005714,0.0000011324943,0.000001235154,0.0021048393,0.99644786,0.00016133927],"about_ca_topic_score_codex":0.000012650253,"about_ca_topic_score_gemma":0.0000014388902,"teacher_disagreement_score":0.9958466,"about_ca_system_score_codex":0.000008229664,"about_ca_system_score_gemma":0.000029492496,"threshold_uncertainty_score":0.9998285},"labels":[],"label_agreement":null},{"id":"W2007964716","doi":"10.1016/j.biologicals.2011.08.009","title":"WHO/KFDA joint workshop on implementing WHO guidelines on evaluating similar biotherapeutic products, Seoul, Republic of Korea 24–26 August, 2010","year":2011,"lang":"en","type":"review","venue":"Biologicals","topic":"Biotechnology and Related Fields","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"U.S. Food and Drug Administration; Pan American Health Organization; Korea Food and Drug Administration","keywords":"Comparability; Terminology; Reimbursement; Quality (philosophy); Directive; Business; Diversity (politics); Food and drug administration; Medicine; Biotechnology; Process management; Political science; Risk analysis (engineering); Computer science; Health care; Biology","score_opus":0.4036703566443834,"score_gpt":0.44595389250951556,"score_spread":0.04228353586513217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007964716","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00036778173,0.98655504,0.000020206135,0.0075341403,0.0007249584,0.0022546637,0.000043926135,0.0003860226,0.0021132433],"genre_scores_gemma":[0.000029647133,0.9890061,0.0022830137,0.0019463226,0.0006009803,0.000116553434,0.00016123998,0.00009162951,0.005764488],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9949482,0.0004869372,0.00219435,0.0012578352,0.0003144053,0.0007982892],"domain_scores_gemma":[0.9960795,0.00038132747,0.0015166947,0.0014447459,0.00044768126,0.00013003084],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0029729148,0.00081776764,0.003255637,0.0005283966,0.00018542698,0.000020532227,0.0004994595,0.008159764,0.0010703781],"category_scores_gemma":[0.0036336775,0.0004500284,0.00072601216,0.00081556255,0.00036644825,0.000034163862,0.00028010356,0.004286356,0.000120806086],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007762143,0.00024744106,0.00001601196,0.003661528,0.0007804378,0.000021090089,0.00002383683,4.4488712e-7,0.0002112883,0.0014027599,0.028237347,0.96532017],"study_design_scores_gemma":[0.0004472765,0.0015886532,0.000061980245,0.02509432,0.0011089076,0.00007123331,0.000029971985,0.000012128645,0.0003880975,0.0001493092,0.9705756,0.00047253005],"about_ca_topic_score_codex":0.000015623127,"about_ca_topic_score_gemma":0.0000012745245,"teacher_disagreement_score":0.9648477,"about_ca_system_score_codex":0.000094666146,"about_ca_system_score_gemma":0.00029448344,"threshold_uncertainty_score":0.99984276},"labels":[],"label_agreement":null},{"id":"W2019553456","doi":"10.1016/j.biologicals.2004.07.001","title":"Assessment of the viral safety of antivenoms fractionated from equine plasma","year":2004,"lang":"en","type":"review","venue":"Biologicals","topic":"Venomous Animal Envenomation and Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Virology; Chemistry; Medicine; Chromatography","score_opus":0.04088139963661249,"score_gpt":0.3486313691422732,"score_spread":0.30774996950566075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019553456","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0041610454,0.99216944,0.00013929873,0.000020872254,0.00017133918,0.00043694602,0.0008771072,0.00000715134,0.0020168014],"genre_scores_gemma":[0.06772472,0.93117964,0.00033803208,0.000020351188,0.00007833255,0.000020763448,0.00047813027,0.00001087829,0.00014916032],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99874055,0.00018396792,0.0005648176,0.00028519926,0.00010308975,0.00012236566],"domain_scores_gemma":[0.99895376,0.000053572283,0.00061430066,0.00028041328,0.00007469445,0.000023261377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015401865,0.0002161241,0.0008644332,0.000022598864,0.000058180973,0.0000038066146,0.00028927112,0.0003444055,0.0000795789],"category_scores_gemma":[0.00011055925,0.00011456648,0.00045841248,0.00008752899,0.00018753194,0.0000010955126,0.00025318284,0.00012570321,0.0000039843567],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003239359,0.002637114,0.0021849102,0.011403931,0.006998515,0.000011789721,0.00007075993,0.0002563414,0.122777596,0.014785459,0.001138719,0.8374109],"study_design_scores_gemma":[0.00029612985,0.00054848345,0.0048800544,0.0013065201,0.00018475359,0.0000037307361,0.00001272951,0.0000028412385,0.0006297738,0.00010081079,0.9918304,0.00020373827],"about_ca_topic_score_codex":0.000023926983,"about_ca_topic_score_gemma":0.0000037753575,"teacher_disagreement_score":0.9906917,"about_ca_system_score_codex":0.000033144857,"about_ca_system_score_gemma":0.0001636111,"threshold_uncertainty_score":0.46718854},"labels":[],"label_agreement":null},{"id":"W2019940052","doi":"10.1016/j.biologicals.2006.02.008","title":"Developments in the production and quality control of poliovirus vaccines – Historical perspectives","year":2006,"lang":"en","type":"article","venue":"Biologicals","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Poliovirus; Virology; Poliomyelitis; Attenuated vaccine; Medicine; Inactivated Poliovirus Vaccine; Virus; Poliomyelitis vaccine; Biology; Immunization; Immunology; Antibody","score_opus":0.07321940373663421,"score_gpt":0.3617862490188297,"score_spread":0.2885668452821955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019940052","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923583,0.003645238,0.000019779975,0.0024644698,0.00003898984,0.00023614052,0.0000013172622,0.000009868217,0.0012258868],"genre_scores_gemma":[0.999194,0.00024967483,0.00006255591,0.000052962994,0.000059429956,0.000023644552,0.0000015073185,0.0000013672408,0.00035480878],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99935967,0.00018264854,0.000172632,0.00012697229,0.000058349437,0.000099721074],"domain_scores_gemma":[0.99969345,0.00010541961,0.000039024388,0.0000853026,0.00006701903,0.0000097990105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005038846,0.000048165915,0.00016878358,0.00006423415,0.000044097003,0.0000030794654,0.000033326778,0.000064018335,0.000013827443],"category_scores_gemma":[0.00076550414,0.000023841976,0.000024635978,0.0001527423,0.00008585465,0.000020313715,0.000012657385,0.00009807531,0.0000024395554],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025386107,0.00043860616,0.89428854,0.000012376273,0.000020706168,0.000002036368,0.00014956458,4.0626506e-7,0.09820552,0.004426621,0.00033415086,0.001867634],"study_design_scores_gemma":[0.00034738862,0.0002587033,0.99542063,0.0000088004135,0.0000053773606,0.0000132837395,0.00027772575,5.8976923e-7,0.00088049256,0.00017249849,0.0025844874,0.000030030338],"about_ca_topic_score_codex":0.0006466351,"about_ca_topic_score_gemma":0.00002865451,"teacher_disagreement_score":0.1011321,"about_ca_system_score_codex":0.0000721413,"about_ca_system_score_gemma":0.000017777162,"threshold_uncertainty_score":0.09775231},"labels":[],"label_agreement":null},{"id":"W2021405109","doi":"10.1016/j.biologicals.2013.11.011","title":"Report on the international workshop on alternatives to the murine histamine sensitization test (HIST) for acellular pertussis vaccines: State of the science and the path forward","year":2014,"lang":"en","type":"article","venue":"Biologicals","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada); Health Canada","funders":"National Institutes of Health; U.S. Food and Drug Administration; Henan Institute of Science and Technology; National Institute of Environmental Health Sciences; University of Virginia","keywords":"Test (biology); Medicine; Immunology; Biology","score_opus":0.018992041529765327,"score_gpt":0.256287146343748,"score_spread":0.23729510481398267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021405109","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9623226,0.00008215293,0.00057098694,0.035193272,0.00079450133,0.0006211504,0.000042399028,0.000013934388,0.0003590275],"genre_scores_gemma":[0.9967047,0.00007796728,0.000019615998,0.000978004,0.00010907796,0.000074211544,0.000015704993,0.0000046034847,0.0020161083],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991479,0.00018270711,0.00024508117,0.00023937224,0.000039957267,0.00014500404],"domain_scores_gemma":[0.9970974,0.0020996057,0.00020665601,0.0003471925,0.00023816628,0.000011006133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015345628,0.00011243977,0.00015822459,0.000036690824,0.00047955778,0.00003639922,0.00037383696,0.00004885794,0.00005279907],"category_scores_gemma":[0.00606066,0.000034950976,0.00006488478,0.00015947048,0.00038594127,0.000026302258,0.00016905797,0.00009814744,0.00000862818],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008601824,0.00022890589,0.0048066783,0.000007852327,0.00013299976,5.000019e-7,0.00051779405,0.0001287496,0.94447184,0.024614187,0.007389145,0.016841153],"study_design_scores_gemma":[0.0029302994,0.0013094957,0.21619935,0.00016925932,0.000086826454,0.000119262,0.00034306472,0.0009434429,0.26098186,0.0043271505,0.5122218,0.00036817088],"about_ca_topic_score_codex":0.000030966356,"about_ca_topic_score_gemma":0.00001787338,"teacher_disagreement_score":0.68349,"about_ca_system_score_codex":0.000026833657,"about_ca_system_score_gemma":0.00002080005,"threshold_uncertainty_score":0.7255614},"labels":[],"label_agreement":null},{"id":"W2023560212","doi":"10.1016/j.biologicals.2006.03.008","title":"Polio vaccine development in Canada: Contributions to global polio eradication","year":2006,"lang":"en","type":"article","venue":"Biologicals","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Canadian Heritage; Sanofi (Canada)","funders":"Hospital for Sick Children; World Bank Group","keywords":"Poliomyelitis; Poliomyelitis eradication; Disease Eradication; Political science; Polio vaccine; Polio Vaccination; Economic growth; Immunization; Medicine; Virology; Poliovirus; Economics; Immunology","score_opus":0.01734293174339808,"score_gpt":0.32757614124104717,"score_spread":0.3102332094976491,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023560212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864033,0.000535356,0.00021409856,0.00986195,0.00005831799,0.00034058728,0.000039456892,0.000025952453,0.0025209794],"genre_scores_gemma":[0.9984254,0.000029387369,0.00027738014,0.000744233,0.000066812114,0.00006510436,0.00009444906,0.0000021826406,0.00029501232],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99914056,0.000049572216,0.00024813888,0.00016608997,0.000082619896,0.00031298934],"domain_scores_gemma":[0.9996541,0.000027080448,0.000026501195,0.00012131766,0.00008529249,0.00008570745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015182937,0.00007865795,0.00018638495,0.00007905169,0.00008110046,0.0000060981565,0.00006132525,0.0000811557,0.00013219303],"category_scores_gemma":[0.00019768102,0.000055351305,0.000021307244,0.0004762169,0.000019653857,0.000016466212,0.000040927276,0.00010514614,0.00008895785],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013443606,0.00025686822,0.9558222,0.0000040698646,0.00003296705,0.000026860014,0.000005266252,0.000018367258,0.016782831,0.0060322518,0.013374473,0.007509379],"study_design_scores_gemma":[0.00053353945,0.00012999824,0.9244638,0.000012062574,0.0000035189119,0.000020553669,0.000011839123,0.000009421424,0.0024527484,0.0001877492,0.07211213,0.00006260321],"about_ca_topic_score_codex":0.6450055,"about_ca_topic_score_gemma":0.59538496,"teacher_disagreement_score":0.058737658,"about_ca_system_score_codex":0.0017279502,"about_ca_system_score_gemma":0.0010938437,"threshold_uncertainty_score":0.45185295},"labels":[],"label_agreement":null},{"id":"W2024080232","doi":"10.1016/j.biologicals.2013.03.003","title":"Serogroup quantitation of multivalent polysaccharide and polysaccharide-conjugate meningococcal vaccines from China","year":2013,"lang":"en","type":"article","venue":"Biologicals","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Polysaccharide; Conjugate; Microbiology; Neisseria meningitidis; Meningococcal vaccine; Conjugate vaccine; Meningococcal meningitis; Virology; Chemistry; Biology; Bacteria; Antibiotics; Biochemistry; Streptococcus pneumoniae","score_opus":0.016801315187519855,"score_gpt":0.24621596020069636,"score_spread":0.22941464501317652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024080232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967999,0.0016504329,0.00011361728,0.00038063986,0.000507384,0.00033441986,0.00006861133,0.00008736189,0.000057625468],"genre_scores_gemma":[0.9989927,0.00029446767,0.00028494193,0.000038114384,0.00006596676,0.000056990353,0.000063825515,0.000008988292,0.00019401015],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988511,0.00016712912,0.00040999067,0.00031722934,0.000012604108,0.00024195193],"domain_scores_gemma":[0.9993112,0.00020417255,0.00019563537,0.00018325078,0.00007414976,0.00003160874],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001410877,0.00018940319,0.00037741353,0.00007680542,0.00012007602,0.000026237216,0.00012380186,0.00027571476,0.0025017867],"category_scores_gemma":[0.0001379834,0.00012603228,0.00008159963,0.000093722985,0.000096331016,0.00014987744,0.00010604203,0.00012755566,0.00022823543],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060884802,0.00008841946,0.07259496,0.0000055371797,0.00009202006,1.6750282e-7,0.000098198856,4.5508372e-7,0.92056155,0.00057771907,0.0002558548,0.0056642117],"study_design_scores_gemma":[0.00076880585,0.00030274325,0.77117896,0.000022146753,0.00003243568,0.000008900305,0.00011295443,0.000011582147,0.22564025,0.0009873454,0.00076719053,0.00016667173],"about_ca_topic_score_codex":0.0043484624,"about_ca_topic_score_gemma":0.000030330595,"teacher_disagreement_score":0.698584,"about_ca_system_score_codex":0.00000880463,"about_ca_system_score_gemma":0.000008748586,"threshold_uncertainty_score":0.99841005},"labels":[],"label_agreement":null},{"id":"W2024454736","doi":"10.1016/j.biologicals.2009.08.018","title":"WHO/KFDA workshop on stability evaluation of vaccines, Seoul, Korea, 23–25 April 2008","year":2009,"lang":"en","type":"article","venue":"Biologicals","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Stability (learning theory); Food and drug administration; Computer science; Operations research; Estimation; Risk analysis (engineering); Medicine; Engineering; Machine learning; Systems engineering","score_opus":0.1377073172535528,"score_gpt":0.36916911471399655,"score_spread":0.23146179746044374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024454736","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9800866,0.0022649348,0.000022871554,0.0024125846,0.00011611386,0.0008423883,0.000030929375,0.00008093942,0.014142592],"genre_scores_gemma":[0.9972145,0.0009115686,0.00030658898,0.001110283,0.00013848407,0.000035348097,0.00005196829,0.000006438417,0.00022481478],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998092,0.0003069366,0.00046901143,0.00038679727,0.00046520404,0.00028007338],"domain_scores_gemma":[0.99845374,0.0003678751,0.00015138238,0.00045207818,0.00047804948,0.00009687672],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015093349,0.0001938052,0.00057714677,0.00006386179,0.00006983735,0.000006081164,0.00010377577,0.00020845828,0.0009393774],"category_scores_gemma":[0.0044147405,0.00012298241,0.00011964696,0.00025027187,0.0000897497,0.000034690147,0.000040941562,0.00016397737,0.00008990654],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010688563,0.002200074,0.51573133,0.00008673425,0.00022912778,0.000021483573,0.0005621923,0.000041620737,0.040467966,0.0014317114,0.04418851,0.3939704],"study_design_scores_gemma":[0.0010833117,0.0010631018,0.9855401,0.00014319865,0.00011331675,0.000003050533,0.000046553545,0.00018098544,0.0052874885,0.0017511746,0.0046363045,0.0001514287],"about_ca_topic_score_codex":0.0000644172,"about_ca_topic_score_gemma":0.00008341647,"teacher_disagreement_score":0.46980876,"about_ca_system_score_codex":0.00013940403,"about_ca_system_score_gemma":0.00007604967,"threshold_uncertainty_score":0.9999739},"labels":[],"label_agreement":null},{"id":"W2025748901","doi":"10.1016/j.biologicals.2009.08.016","title":"Characterization of variant diphtheria toxin–interleukin-3 fusion protein, DTIL3K116W, for phase I clinical trials","year":2009,"lang":"en","type":"article","venue":"Biologicals","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Diphtheria toxin; Diphtheria; Toxin; Microbiology; Medicine; Virology; Chemistry; Biology; Vaccination","score_opus":0.11153700088426086,"score_gpt":0.3937684916551069,"score_spread":0.2822314907708461,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025748901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9756665,0.00049062754,0.019367829,0.00054121984,0.0010101959,0.0022628994,0.000429457,0.000101473684,0.00012979352],"genre_scores_gemma":[0.99595064,0.00021953214,0.0011656665,0.0006115946,0.0001727542,0.00012801882,0.00063116197,0.000013072515,0.001107536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99626255,0.001270747,0.0016030208,0.0004596939,0.000035768953,0.0003682322],"domain_scores_gemma":[0.99815035,0.0004478592,0.00085534615,0.00037719094,0.00013184384,0.000037416634],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0040265014,0.00024980743,0.0010832251,0.00007345271,0.00013107713,0.000018267914,0.00032718803,0.00072196487,0.0013708832],"category_scores_gemma":[0.0021208453,0.00016115732,0.0004645814,0.0001037756,0.00013895323,0.00007601777,0.000057290697,0.00020308944,0.00008647308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017874223,0.0009868369,0.000008340641,0.000008279105,0.00008481877,0.000001873711,0.00003958152,8.0147174e-8,0.91639215,0.0069853305,0.00022755156,0.073477745],"study_design_scores_gemma":[0.005665886,0.007835488,0.002102259,0.000076981734,0.00006619146,0.000013824793,0.000031824817,0.00001393387,0.92697614,0.0029425945,0.05401058,0.00026428304],"about_ca_topic_score_codex":0.0000031042807,"about_ca_topic_score_gemma":3.7865757e-7,"teacher_disagreement_score":0.073213466,"about_ca_system_score_codex":0.000017565084,"about_ca_system_score_gemma":0.00004522652,"threshold_uncertainty_score":0.999542},"labels":[],"label_agreement":null},{"id":"W2033051200","doi":"10.1016/j.biologicals.2012.09.010","title":"Health Canada/BIOTECanada Summit on regulatory and clinical topics related to subsequent entry biologics (biosimilars), Ottawa, Canada, 14 May 2012","year":2012,"lang":"en","type":"article","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Sunnybrook Health Science Centre; Health Canada; University of Toronto; University Health Network; Health Sciences Centre; Mount Sinai Hospital; Western University","funders":"Health Canada","keywords":"Biosimilar; Summit; Medicine; Pharmacovigilance; Comparability; Product (mathematics); Interchangeability; Health care; Family medicine; Pharmacology; Political science; Drug","score_opus":0.040734856054130394,"score_gpt":0.31990770629134835,"score_spread":0.27917285023721794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033051200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8395081,0.026032584,0.000033223056,0.12049186,0.007695685,0.0012943877,0.0011367983,0.00015165539,0.0036557086],"genre_scores_gemma":[0.95027846,0.00085990335,0.00067877537,0.04237476,0.00019554907,0.000013799598,0.00012157863,0.000020182239,0.005456981],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954409,0.0013638962,0.001070301,0.00070429174,0.00012463587,0.0012959853],"domain_scores_gemma":[0.9977721,0.00078140845,0.00028665506,0.0005338937,0.00008184298,0.0005441014],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020708404,0.0004332809,0.0009309805,0.00006156209,0.00031574766,0.000014539696,0.0003901902,0.0009814674,0.00072352786],"category_scores_gemma":[0.0008468038,0.00028869175,0.00013082335,0.00022850245,0.00038828244,0.000041520365,0.00021856284,0.0008049542,0.000027095726],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013073653,0.00021910058,0.15192847,0.000020281075,0.00026102565,0.000017471082,0.000011912546,0.0000010632986,0.0012864412,0.004415338,0.812427,0.029281162],"study_design_scores_gemma":[0.00038673138,0.00049615814,0.2954852,0.00002976612,0.00002968637,0.000017732827,0.000049208382,7.8775406e-7,0.0022603176,0.00006348085,0.7008303,0.00035065],"about_ca_topic_score_codex":0.63262194,"about_ca_topic_score_gemma":0.94935834,"teacher_disagreement_score":0.31673637,"about_ca_system_score_codex":0.0005449878,"about_ca_system_score_gemma":0.0010858044,"threshold_uncertainty_score":0.99995655},"labels":[],"label_agreement":null},{"id":"W2034043843","doi":"10.1006/biol.2002.0322","title":"Thermal Stability: A Means to Assure Tertiary Structure in Therapeutic Proteins","year":2002,"lang":"en","type":"article","venue":"Biologicals","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Protein tertiary structure; Protein secondary structure; Denaturation (fissile materials); Chemistry; Protein structure; Protein folding; Chemical structure; Amino acid; Protein primary structure; Biochemistry; Crystallography; Biophysics; Peptide sequence; Organic chemistry; Biology","score_opus":0.03560368562267057,"score_gpt":0.2410658868471672,"score_spread":0.20546220122449663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034043843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966476,0.00031025594,0.00035546577,0.0008131407,0.00022224036,0.0005006582,0.000039773575,0.00009345985,0.0010173994],"genre_scores_gemma":[0.99773526,0.0000029863577,0.0008115445,0.0011792058,0.0001417743,0.000042790063,0.0000033824422,0.0000074056406,0.00007562073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875313,0.0002136358,0.0002208152,0.0003739128,0.00013475976,0.00030373014],"domain_scores_gemma":[0.9995271,0.000058415233,0.000045441444,0.00027325397,0.000027449387,0.000068319605],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024273133,0.00015102084,0.00019923945,0.00004670268,0.00006151346,0.00003816849,0.00021365963,0.00017776592,0.0072410987],"category_scores_gemma":[0.00009158929,0.00008877113,0.000042977845,0.00018499795,0.000062410196,0.000075200194,0.000054470023,0.00013228122,0.0001621808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027799362,0.000033843415,0.012379013,0.000006259084,0.0000030137348,0.000004104471,0.00024351363,0.000051408497,0.9830742,0.00030900395,0.00008728795,0.0037805445],"study_design_scores_gemma":[0.0005687221,0.0007142103,0.4506688,0.000030162562,0.00001600638,0.000010317259,0.00016336466,0.0001793309,0.5311999,0.0068656453,0.009051528,0.0005320306],"about_ca_topic_score_codex":0.00003200419,"about_ca_topic_score_gemma":0.000088643144,"teacher_disagreement_score":0.45187432,"about_ca_system_score_codex":0.000043674172,"about_ca_system_score_gemma":0.000008425175,"threshold_uncertainty_score":0.9936664},"labels":[],"label_agreement":null},{"id":"W2036701515","doi":"10.1016/j.biologicals.2009.12.005","title":"Approach to the profiling and characterization of influenza vaccine constituents by the combined use of size-exclusion chromatography, gel electrophoresis and mass spectrometry","year":2010,"lang":"en","type":"article","venue":"Biologicals","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Chromatography; Size-exclusion chromatography; Mass spectrometry; Influenza vaccine; Chemistry; Biology; Virology","score_opus":0.013319332817672357,"score_gpt":0.24085189056345518,"score_spread":0.22753255774578282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036701515","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99763006,0.00036546073,0.001115833,0.00020824959,0.000019471678,0.0005515788,0.00007189634,0.000005264214,0.00003220669],"genre_scores_gemma":[0.99778295,0.00028319156,0.0015999316,0.00020912912,0.00001615531,0.000032597247,0.000063757136,0.0000035414673,0.000008748521],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993144,0.000098672135,0.00020963377,0.00021322988,0.00006253188,0.00010150192],"domain_scores_gemma":[0.99945897,0.000048774138,0.00012220038,0.00026284525,0.000069565904,0.000037629987],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003188683,0.00008838987,0.00013673038,0.00001857182,0.00007501889,0.000014594946,0.00012820128,0.00011597074,0.000005212686],"category_scores_gemma":[0.00037876976,0.000045527726,0.00003084293,0.00012910715,0.00015986458,0.0000034903805,0.00009065898,0.00007417808,1.6485893e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011534857,0.000060919385,0.04876869,0.000012073791,0.000016422742,1.8770933e-8,0.000010214452,1.5370031e-7,0.950382,0.0003128701,0.000018436804,0.0003028663],"study_design_scores_gemma":[0.00023159538,0.0001996456,0.25097302,0.000002525377,0.000008608704,0.000002213874,0.000011243461,0.000029080977,0.74613684,0.00006127326,0.0022829648,0.000060962593],"about_ca_topic_score_codex":0.000006716745,"about_ca_topic_score_gemma":0.0000010207448,"teacher_disagreement_score":0.2042451,"about_ca_system_score_codex":0.0000016945805,"about_ca_system_score_gemma":0.000011620001,"threshold_uncertainty_score":0.18565668},"labels":[],"label_agreement":null},{"id":"W2059265705","doi":"10.1016/j.biologicals.2012.09.008","title":"WHO/Health Canada meeting on regulatory considerations for evaluation and licensing of new meningococcal Group B vaccines, Ottawa, Canada, 3–4 October 2011","year":2012,"lang":"en","type":"article","venue":"Biologicals","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Health Canada","funders":"","keywords":"Immunogenicity; Neisseria meningitidis; Meningococcal vaccine; Standardization; Virology; Outbreak; Medicine; Biology; Antigen; Political science; Immunology; Bacteria; Genetics","score_opus":0.04348790936497547,"score_gpt":0.2869290772448645,"score_spread":0.243441167879889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059265705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935251,0.003284046,0.000020561902,0.0015032437,0.0009177754,0.00048393736,0.00007107651,0.000015624531,0.00017862102],"genre_scores_gemma":[0.9985441,0.000029524168,0.00023009683,0.00071071275,0.00016344081,0.000021621567,0.00009412364,0.000006896321,0.00019950712],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.99888325,0.00024491182,0.0003656079,0.00018431382,0.000023888031,0.00029802616],"domain_scores_gemma":[0.9989126,0.00052005844,0.00022263407,0.00013501047,0.00015039602,0.000059329108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006969978,0.00013079801,0.00029677706,0.00003452479,0.00028394331,0.000006881162,0.000035829682,0.0001389571,0.0004289732],"category_scores_gemma":[0.00053710194,0.00009816081,0.000029431365,0.00003762826,0.000026686645,0.000046496687,0.000023949375,0.00008279135,0.0000016515213],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014804675,0.00012728189,0.052700385,0.00004147273,0.00021949086,1.6333514e-7,0.00021208287,0.000021460339,0.30688104,0.009003364,0.61438805,0.016257152],"study_design_scores_gemma":[0.00194527,0.00039986725,0.7728159,0.00006773186,0.00007337622,0.00003176946,0.00017493905,0.000015992107,0.019309886,0.00026690032,0.20460792,0.0002904793],"about_ca_topic_score_codex":0.9104099,"about_ca_topic_score_gemma":0.96061355,"teacher_disagreement_score":0.7201155,"about_ca_system_score_codex":0.00013417825,"about_ca_system_score_gemma":0.00072200526,"threshold_uncertainty_score":0.46969557},"labels":[],"label_agreement":null},{"id":"W2059662302","doi":"10.1016/j.biologicals.2014.05.001","title":"Results of an international transferability study of the BINACLE (binding and cleavage) assay for in vitro detection of tetanus toxicity","year":2014,"lang":"en","type":"article","venue":"Biologicals","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Transferability; Toxicity; In vitro; Tetanus; Cleavage (geology); Chemistry; Pharmacology; Biochemistry; Medicine; Biology; Immunology; Computer science; Organic chemistry","score_opus":0.03225434546825608,"score_gpt":0.2928911571924868,"score_spread":0.26063681172423075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059662302","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987125,0.000012196212,0.00011587794,0.00021510712,0.00006544342,0.00062137126,0.0000307586,0.000009129873,0.0002176312],"genre_scores_gemma":[0.9998218,0.000020167978,0.00008010575,0.000045337783,0.000010013654,0.000009600897,0.0000038899843,0.0000026284551,0.000006458805],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989344,0.00030187654,0.00038726025,0.00019846023,0.00009431137,0.000083687424],"domain_scores_gemma":[0.99932146,0.00034800134,0.00011117164,0.00014742107,0.000044857028,0.000027104388],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00087077665,0.00006782125,0.00027292236,0.000039150444,0.000021690803,0.0000015373324,0.00009317051,0.0001429388,0.0000031363593],"category_scores_gemma":[0.0010871913,0.000035054458,0.00006421562,0.00011341502,0.00014221689,0.00002138192,0.000024451614,0.00012364794,8.777462e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030979537,0.0013268976,0.017054692,0.000024821033,0.000022776312,3.3716088e-7,0.00014414615,0.000012223924,0.962888,0.00002261648,7.1252106e-7,0.015404833],"study_design_scores_gemma":[0.0029830944,0.003728795,0.55961794,0.000013284047,0.000022707934,0.0000014956584,0.00016799767,0.00059762807,0.4325148,0.00029296693,0.000022778348,0.00003654171],"about_ca_topic_score_codex":0.000030104413,"about_ca_topic_score_gemma":0.000023704899,"teacher_disagreement_score":0.5425632,"about_ca_system_score_codex":0.000008693696,"about_ca_system_score_gemma":0.000004851931,"threshold_uncertainty_score":0.14294793},"labels":[],"label_agreement":null},{"id":"W2061592265","doi":"10.1016/j.biologicals.2011.09.004","title":"Evaluation of similar biotherapeutic products: Scientific and regulatory challenges","year":2011,"lang":"en","type":"editorial","venue":"Biologicals","topic":"Biotechnology and Related Fields","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Biochemical engineering; Computational biology; Chemistry; Computer science; Biology; Engineering","score_opus":0.10610936778380496,"score_gpt":0.32570991743955285,"score_spread":0.21960054965574788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061592265","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.027990146,0.34082046,0.0000021255871,0.0057355366,0.62094665,0.0013668637,0.00004656176,0.00018400488,0.0029076727],"genre_scores_gemma":[0.24291222,0.19927132,0.0012759283,0.00021073212,0.55214757,0.0001703272,0.0006492254,0.00009990547,0.0032627422],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982065,0.00021957004,0.0003009835,0.0005797583,0.00051452674,0.00017866427],"domain_scores_gemma":[0.99825174,0.00013237815,0.00022719953,0.0005279329,0.00081778073,0.00004294719],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.003210573,0.00019655883,0.000498417,0.00017678263,0.00006781868,0.0000054681555,0.00012902933,0.010491345,0.0001300698],"category_scores_gemma":[0.0018768775,0.00012108227,0.00006399824,0.00013764865,0.0010459239,0.000017606886,0.00006244595,0.0015315633,0.000013009788],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003542362,0.00064045435,0.00005771818,0.0010997113,0.001172645,0.00001049485,0.0003169277,2.0138249e-7,0.03539459,0.0020790307,0.8190087,0.13986526],"study_design_scores_gemma":[0.0008485266,0.0008523102,0.0013894023,0.0003840255,0.0010540149,0.000007427124,0.00003898205,0.000006909855,0.008360435,0.0027686956,0.9840888,0.00020046491],"about_ca_topic_score_codex":0.0000019784845,"about_ca_topic_score_gemma":0.0000011306471,"teacher_disagreement_score":0.21492207,"about_ca_system_score_codex":0.000033325414,"about_ca_system_score_gemma":0.00031708882,"threshold_uncertainty_score":0.9907932},"labels":[],"label_agreement":null},{"id":"W2070941941","doi":"10.1016/j.biologicals.2011.11.001","title":"Preparation of blood products for transfusion: Is there a best method?","year":2011,"lang":"en","type":"review","venue":"Biologicals","topic":"Blood donation and transfusion practices","field":"Business, Management and Accounting","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; University of British Columbia","funders":"","keywords":"Buffy coat; Blood component; Apheresis; Production (economics); Blood donor; Whole blood; Intensive care medicine; Blood collection; Plateletpheresis; Medicine; Platelet; Surgery; Immunology; Medical emergency","score_opus":0.16823236442323372,"score_gpt":0.3922269800614754,"score_spread":0.22399461563824166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070941941","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000033253957,0.9834348,0.00054224406,0.00021722639,0.0002738124,0.0022052617,0.000053758467,0.00007641114,0.013163206],"genre_scores_gemma":[0.000078259356,0.9941114,0.0034637523,0.0002991095,0.0006296855,0.0003835723,0.00015645158,0.000027614326,0.00085016224],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99835676,0.00007916426,0.0007062049,0.00054949004,0.0001236807,0.00018471484],"domain_scores_gemma":[0.9982358,0.00028236705,0.000849134,0.0003060263,0.00031667223,0.000009954441],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009258263,0.0003228548,0.0010619258,0.00017731884,0.00010900471,0.000072622875,0.0003338036,0.00040471862,0.0014740843],"category_scores_gemma":[0.0003176014,0.00019731968,0.00042296477,0.00044489407,0.000047895934,0.00035923714,0.000049839873,0.0001470303,0.00018756218],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048091493,0.0005181826,0.000007637056,0.014736664,0.00026547417,0.0000010811339,0.000026316926,4.662072e-8,0.000031294316,0.016663708,0.0008733882,0.9668281],"study_design_scores_gemma":[0.0002725613,0.000083647385,0.000004170401,0.0012457493,0.0024358279,0.0000039642014,0.000014095359,0.0000034342156,0.000065601984,0.00086514466,0.99475545,0.00025035554],"about_ca_topic_score_codex":0.00006268965,"about_ca_topic_score_gemma":0.000007334112,"teacher_disagreement_score":0.99388206,"about_ca_system_score_codex":0.000003492823,"about_ca_system_score_gemma":0.000050113264,"threshold_uncertainty_score":0.9994387},"labels":[],"label_agreement":null},{"id":"W2076094047","doi":"10.1016/j.biologicals.2010.12.001","title":"The consistency approach for quality control of vaccines – A strategy to improve quality control and implement 3Rs","year":2011,"lang":"en","type":"article","venue":"Biologicals","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":81,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Joint Research Centre; Health Canada; European Commission","keywords":"Consistency (knowledge bases); Quality (philosophy); Harmonization; Risk analysis (engineering); Production (economics); Control (management); Product (mathematics); Computer science; Biotechnology; Quality management system; Biochemical engineering; Business; Engineering; Quality management; Mathematics; Marketing; Biology","score_opus":0.07057180977114384,"score_gpt":0.3179325884712634,"score_spread":0.24736077870011952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076094047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93258905,0.006988675,0.05175852,0.00039945813,0.0006375032,0.0045507182,0.001800724,0.000089755245,0.0011856208],"genre_scores_gemma":[0.9978663,0.00008324369,0.00089817523,0.00041142997,0.000021587683,0.00045585376,0.00003132495,0.000008017666,0.00022408187],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976432,0.0006578664,0.0008068543,0.00040521254,0.000030673735,0.00045624212],"domain_scores_gemma":[0.99801946,0.0010289743,0.0003491233,0.00039394462,0.00016674875,0.0000417579],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022602163,0.00021932245,0.0006358356,0.000028022278,0.00029278814,0.000014951797,0.00029479794,0.00026835574,0.00012421196],"category_scores_gemma":[0.00070027687,0.000117790616,0.00017186627,0.000052423704,0.00020231974,0.000031099848,0.000077023346,0.00012359075,0.000008706354],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017042316,0.00021793792,0.0021167574,0.000027422468,0.0003049755,1.4515255e-7,0.00014372116,2.8075635e-7,0.8748558,0.10483004,0.0001740099,0.015624671],"study_design_scores_gemma":[0.02914975,0.017538257,0.5351995,0.000035599056,0.000398561,0.000023183771,0.008669941,0.000032134292,0.35327825,0.02855616,0.025607813,0.0015108698],"about_ca_topic_score_codex":0.00025988065,"about_ca_topic_score_gemma":0.000026939697,"teacher_disagreement_score":0.5330827,"about_ca_system_score_codex":0.000013761919,"about_ca_system_score_gemma":0.00004134353,"threshold_uncertainty_score":0.4803362},"labels":[],"label_agreement":null},{"id":"W2077952077","doi":"10.1016/j.biologicals.2011.09.005","title":"Biosimilars – Global issues, national solutions","year":2011,"lang":"en","type":"review","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Biosimilar; Biochemical engineering; Biotechnology; Biology; Engineering","score_opus":0.31092367599587706,"score_gpt":0.43790269373568413,"score_spread":0.12697901773980708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077952077","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[1.5453526e-7,0.9804271,0.000070261354,0.00023836932,0.0009878441,0.00047564032,0.0016423233,0.00016750224,0.01599081],"genre_scores_gemma":[0.000003021698,0.9942403,0.0013852943,0.00064884964,0.00016638146,0.000088862,0.0004665422,0.000017108192,0.0029836586],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99656653,0.0010602764,0.00081346184,0.000776398,0.000053065007,0.0007302653],"domain_scores_gemma":[0.9987481,0.00033004105,0.00033884752,0.00037564244,0.00014011408,0.00006722994],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00096480723,0.00058493647,0.001875475,0.00009833097,0.00023980967,0.000023553313,0.0007278225,0.0024374174,0.006149478],"category_scores_gemma":[0.0006297686,0.0003440834,0.0009628044,0.00043967183,0.00070608547,0.000032705564,0.0003913339,0.00057046,0.0029776662],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001050281,0.00021510152,0.000006221886,0.00046085726,0.0006357212,0.0000049338337,0.0000020425482,7.1728943e-9,0.000011524927,0.03190018,0.13513187,0.83162105],"study_design_scores_gemma":[0.00012372833,0.00014742756,0.000026849551,0.0007202913,0.0004901838,0.00011889866,0.000002410273,7.1164635e-8,0.0000060556313,0.0035636749,0.99433994,0.00046046343],"about_ca_topic_score_codex":0.0000123407835,"about_ca_topic_score_gemma":0.0000034066104,"teacher_disagreement_score":0.85920805,"about_ca_system_score_codex":0.00015739295,"about_ca_system_score_gemma":0.00022602512,"threshold_uncertainty_score":0.9999011},"labels":[],"label_agreement":null},{"id":"W2080125481","doi":"10.1006/biol.2001.0280","title":"A Quantitative Analysis for the ADP-Ribosylation Activity of Pertussis Toxin: An Enzymatic-HPLC Coupled Assay Applicable to Formulated Whole Cell and Acellular Pertussis Vaccine Products","year":2001,"lang":"en","type":"article","venue":"Biologicals","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Pertussis toxin; Bordetella pertussis; Biochemistry; ADP-ribosylation; NAD+ kinase; Peptide; Chemistry; Toxin; G protein; Enzyme; Molecular biology; Biology; Receptor; Bacteria","score_opus":0.04670270189066684,"score_gpt":0.31758877396226753,"score_spread":0.2708860720716007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080125481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9301094,0.0005400499,0.063931696,0.002900526,0.000021949381,0.0022745344,0.000084563864,0.00005141448,0.000085861844],"genre_scores_gemma":[0.9883362,0.0001751278,0.010107899,0.000275537,0.000054407712,0.00018463592,0.00009397176,0.00001906828,0.0007531334],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99827,0.00014590872,0.00043832464,0.0005767108,0.00020162502,0.0003674558],"domain_scores_gemma":[0.9976223,0.00094851345,0.00029269903,0.00054673315,0.00043413212,0.00015562463],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000918844,0.00025813162,0.00081355846,0.00017038992,0.0001909911,0.000032034935,0.00017167372,0.00019226002,0.00009557788],"category_scores_gemma":[0.0012280403,0.00014549006,0.00018720335,0.0012167075,0.00009377957,0.00010540185,0.000068148634,0.00012309969,0.000007527206],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023276052,0.0005247708,0.014841798,0.00010268176,0.00039770533,0.0000032377848,0.0002927748,0.00028925797,0.9785537,0.00012788443,0.00031027143,0.002228302],"study_design_scores_gemma":[0.004357122,0.0050770813,0.43777907,0.00013144422,0.0032213095,0.000008843514,0.0012110869,0.16982238,0.3591177,0.0002429849,0.018221615,0.00080939283],"about_ca_topic_score_codex":0.0001105392,"about_ca_topic_score_gemma":0.000057944482,"teacher_disagreement_score":0.619436,"about_ca_system_score_codex":0.000060483395,"about_ca_system_score_gemma":0.000042833974,"threshold_uncertainty_score":0.5932913},"labels":[],"label_agreement":null},{"id":"W2081733255","doi":"10.1016/j.biologicals.2009.11.010","title":"Influence of bovine serum albumin on the secondary structure of interferon alpha 2b as determined by far UV circular dichroism spectropolarimetry","year":2009,"lang":"en","type":"article","venue":"Biologicals","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"Circular dichroism; Protein secondary structure; Excipient; Bovine serum albumin; Chemistry; Protein tertiary structure; Alpha interferon; Albumin; Protein structure; Serum albumin; Alpha (finance); Chromatography; Interferon; Biochemistry; Immunology; Biology; Medicine; Surgery","score_opus":0.006941510629092174,"score_gpt":0.24706830781758232,"score_spread":0.24012679718849014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081733255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965416,0.0020337298,0.00010945858,0.0005441087,0.000020030027,0.00028950558,0.0001945022,0.000009904096,0.0002571414],"genre_scores_gemma":[0.9984774,0.00012140199,0.00007942737,0.0011378794,0.000031132655,0.0000035761263,0.00008456616,0.000005275216,0.00005935011],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988573,0.00018345035,0.00033519906,0.00033781922,0.0001068999,0.00017929451],"domain_scores_gemma":[0.99907845,0.000035999663,0.00019803933,0.0005553437,0.00007887071,0.00005329374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021764319,0.00016395438,0.00022919467,0.000022984035,0.000045505505,0.0000070953133,0.0003837692,0.00024500946,0.0001572715],"category_scores_gemma":[0.0004206498,0.00009992049,0.0001025687,0.00008818661,0.00024157294,0.0000035164437,0.00006503553,0.00015259717,0.0000038033959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016106463,0.00008708848,0.0014193733,0.000010715101,0.000023183504,6.2415927e-7,0.000011335255,0.0000027424064,0.9949759,0.00040183426,0.00013273428,0.0027733522],"study_design_scores_gemma":[0.00021254731,0.002010267,0.08289477,0.000008714083,0.000007495904,0.0000045578945,0.000018860164,0.0000034870332,0.908211,0.0011293815,0.0053848233,0.00011410189],"about_ca_topic_score_codex":0.000018550109,"about_ca_topic_score_gemma":0.0000022038942,"teacher_disagreement_score":0.08676496,"about_ca_system_score_codex":0.000013192688,"about_ca_system_score_gemma":0.000042989748,"threshold_uncertainty_score":0.40746394},"labels":[],"label_agreement":null},{"id":"W2082256485","doi":"10.1016/j.biologicals.2013.09.002","title":"Neutralization of cobra venom by cocktail antiserum against venom proteins of cobra (Naja naja naja)","year":2013,"lang":"en","type":"article","venue":"Biologicals","topic":"Venomous Animal Envenomation and Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University","funders":"","keywords":"Venom; Naja; Antiserum; Neutralization; Biology; Antivenom; In vivo; Molecular biology; Antibody; Biochemistry; Immunology","score_opus":0.008960809197759838,"score_gpt":0.22084922252543082,"score_spread":0.21188841332767097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082256485","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991016,0.0027459594,0.0008984051,0.0002601546,0.00007006581,0.0006277724,0.00017269977,0.000023684252,0.0041852687],"genre_scores_gemma":[0.9972505,0.00095375895,0.0003543167,0.00032344478,0.00006745128,0.000064950356,0.0003603754,0.000016381855,0.00060880586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986926,0.00011597202,0.00047378507,0.00033982642,0.00011735514,0.0002604666],"domain_scores_gemma":[0.9991259,0.00002179668,0.0003244885,0.00023999323,0.00021171998,0.000076103715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015754478,0.00020373992,0.0003874216,0.000035911566,0.000092662754,0.000016526632,0.00023687202,0.0002536795,0.00013735774],"category_scores_gemma":[0.00014384373,0.00016095968,0.0001359943,0.0001175463,0.00023991326,0.000007938799,0.00013832157,0.00006915599,0.000029517436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043115047,0.00024517896,0.0042843665,0.000056669356,0.0000740445,0.0000016789397,0.000044892433,0.000023768307,0.9883056,0.0015337932,0.003808272,0.0015785703],"study_design_scores_gemma":[0.0014304568,0.0033075695,0.06624568,0.00008938353,0.000043298776,0.000014134714,0.0003449106,0.00018263675,0.767917,0.00039157303,0.15937576,0.0006576169],"about_ca_topic_score_codex":0.00004353658,"about_ca_topic_score_gemma":0.000005793253,"teacher_disagreement_score":0.22038867,"about_ca_system_score_codex":0.000012269015,"about_ca_system_score_gemma":0.000037100082,"threshold_uncertainty_score":0.6563745},"labels":[],"label_agreement":null},{"id":"W2087287783","doi":"10.1016/j.biologicals.2007.11.004","title":"WHO informal consultation on regulatory evaluation of therapeutic biological medicinal products held at WHO Headquarters, Geneva, 19–20 April 2007","year":2008,"lang":"en","type":"article","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Biosimilar; Terminology; Innovator; Product (mathematics); Medicine; Business; Quality (philosophy); Regulatory science; Political science; Intellectual property; Law","score_opus":0.1320325286439629,"score_gpt":0.3391617240837612,"score_spread":0.20712919543979832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087287783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98718584,0.0075768162,0.00010863453,0.0011459544,0.00049320434,0.00075596,0.00006998104,0.0000698494,0.0025937585],"genre_scores_gemma":[0.9950498,0.00058075966,0.00033799288,0.0022736138,0.0001281606,0.00004080308,0.00016419166,0.00000851973,0.0014161941],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9968617,0.0012582277,0.0006912543,0.0005280093,0.00019824987,0.00046255544],"domain_scores_gemma":[0.9981635,0.0006481498,0.00032364146,0.0003897702,0.00040652373,0.000068367015],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0025537687,0.00029374857,0.00063246064,0.00009399363,0.00026479608,0.0000050018034,0.00024842913,0.0007783324,0.001726993],"category_scores_gemma":[0.001386179,0.00017406014,0.00014673313,0.00025463628,0.0013599362,0.000054007036,0.00008393221,0.00029821388,0.00015569404],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032969771,0.00075992907,0.042562615,0.000063977626,0.00056154,0.00001187384,0.0006631205,0.00003298176,0.84604424,0.0036028607,0.031516608,0.07088328],"study_design_scores_gemma":[0.0044414415,0.0051199645,0.65542626,0.000102752434,0.00023314364,0.00020504846,0.0002315324,0.00014608992,0.25434366,0.00076501665,0.07833256,0.00065251417],"about_ca_topic_score_codex":0.0000088759125,"about_ca_topic_score_gemma":0.0000024468754,"teacher_disagreement_score":0.61286366,"about_ca_system_score_codex":0.000087394124,"about_ca_system_score_gemma":0.00012513432,"threshold_uncertainty_score":0.99918556},"labels":[],"label_agreement":null},{"id":"W2088499232","doi":"10.1016/j.biologicals.2011.06.006","title":"Statistical considerations for confirmatory clinical trials for similar biotherapeutic products","year":2011,"lang":"en","type":"review","venue":"Biologicals","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Equivalence (formal languages); Clinical trial; Medicine; Product (mathematics); Computer science; Risk analysis (engineering); Mathematics; Pathology","score_opus":0.9821581373665009,"score_gpt":0.749156292279861,"score_spread":0.2330018450866399,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088499232","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":"methods","model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[1.9053672e-7,0.7007928,0.2668809,0.00020582436,0.0026738003,0.016376346,0.0126089305,0.00025532153,0.00020590809],"genre_scores_gemma":[3.6995837e-7,0.49784568,0.4968252,0.00039456412,0.0015536596,0.0030666383,0.000090094625,0.00009313239,0.00013066905],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.96934974,0.018105922,0.009626751,0.0017879974,0.00023900988,0.0008905925],"domain_scores_gemma":[0.3666791,0.6279801,0.0032331394,0.001119536,0.0006132869,0.00037482215],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.059459735,0.0010351496,0.012814905,0.0001505988,0.00026053318,0.00011315733,0.0006456966,0.0026159512,0.001570485],"category_scores_gemma":[0.8325521,0.0006231966,0.0027370758,0.00018587934,0.0011112859,0.00003756221,0.00014917829,0.0008060447,0.00011835555],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012671888,0.00044447122,6.0009603e-7,0.009767089,0.0008568918,0.0000035779274,0.000005482214,4.641664e-9,9.0035553e-7,0.4774035,0.041819885,0.46957088],"study_design_scores_gemma":[0.0007541576,0.00064204674,7.0775013e-7,0.0010105916,0.002750321,0.000007899724,0.0000025105592,0.0000031325376,0.0000030283586,0.48101112,0.5133791,0.00043540017],"about_ca_topic_score_codex":8.0638944e-7,"about_ca_topic_score_gemma":6.715396e-7,"teacher_disagreement_score":0.7730923,"about_ca_system_score_codex":0.00007571301,"about_ca_system_score_gemma":0.000900178,"threshold_uncertainty_score":0.9996219},"labels":[],"label_agreement":null},{"id":"W2089623432","doi":"10.1016/j.biologicals.2015.01.004","title":"Review of the current use and evaluation of cell substrates for producing biologicals in selected countries","year":2015,"lang":"en","type":"review","venue":"Biologicals","topic":"Medical Device Sterilization and Disinfection","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"World Health Organization","keywords":"China; Beijing; Political science; Medicine; Engineering management; Business; Library science; Computer science; Engineering","score_opus":0.20558237438473587,"score_gpt":0.4087074877431298,"score_spread":0.20312511335839395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089623432","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004211556,0.9922809,0.000008056969,0.000022425298,0.00035260734,0.002895071,0.00018467942,0.00001300333,0.00003168675],"genre_scores_gemma":[0.0019802696,0.99701846,0.000012666977,0.000057244866,0.000016958045,0.00023720205,0.00065271166,0.000005961904,0.000018523318],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965851,0.0018708514,0.0009669663,0.00034400422,0.0000637585,0.00016935369],"domain_scores_gemma":[0.99738675,0.00071450777,0.0008508024,0.00023007444,0.0007997295,0.000018133942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030918391,0.0002200566,0.0013390242,0.00007081252,0.000036816764,0.0000061376504,0.00015857136,0.00039379613,0.0001313425],"category_scores_gemma":[0.0057045813,0.00010342912,0.00015757217,0.0003882671,0.0002842806,0.000033226173,0.00006998622,0.00019568096,0.0000064536625],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046494242,0.0002867833,0.0010471175,0.11851992,0.000092110364,6.0111674e-8,0.00004569115,4.5914047e-7,0.000916943,0.00021442505,0.0031266587,0.87570333],"study_design_scores_gemma":[0.0004771857,0.0001812745,0.0014301463,0.04196804,0.0006092941,0.000004831138,0.000005817751,0.0000011697584,0.00040816754,0.00012995627,0.9546187,0.00016540804],"about_ca_topic_score_codex":0.0000066788057,"about_ca_topic_score_gemma":0.00000503087,"teacher_disagreement_score":0.9514921,"about_ca_system_score_codex":0.000040342715,"about_ca_system_score_gemma":0.0003493327,"threshold_uncertainty_score":0.68293285},"labels":[],"label_agreement":null},{"id":"W2097551778","doi":"10.1016/j.biologicals.2012.03.003","title":"Evaluation of a candidate International Standard for Meningococcal Group C polysaccharide","year":2012,"lang":"en","type":"article","venue":"Biologicals","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health Canada","keywords":"Meningococcal vaccine; Neisseria meningitidis; Chemistry; Chromatography; Biology","score_opus":0.23618787003599698,"score_gpt":0.47472832979962504,"score_spread":0.23854045976362806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097551778","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99369955,0.0014979449,0.0007614113,0.0004345775,0.00017748908,0.0008669615,0.00015484166,0.000025184045,0.002382032],"genre_scores_gemma":[0.9971935,0.00008037994,0.002000583,0.00016742964,0.0002635509,0.00020976391,0.000028185159,0.0000045337647,0.000052078285],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988586,0.00009118937,0.00020460549,0.0001122691,0.0005023847,0.0002310094],"domain_scores_gemma":[0.9990391,0.00015124466,0.00007277977,0.00009761219,0.00056659454,0.00007267204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00298608,0.00007093268,0.00020131185,0.00006201118,0.000040732102,0.000004570841,0.00006795428,0.00006126096,0.0003535104],"category_scores_gemma":[0.0029291029,0.000043924323,0.00007188541,0.000056904348,0.00008670564,0.000051448067,0.000060900373,0.000055948512,0.0000099515855],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003655714,0.00043657448,0.21567716,0.00007153628,0.0009467878,0.0000011472706,0.0006084385,0.000006453805,0.6579964,0.008214276,0.0045106295,0.10787487],"study_design_scores_gemma":[0.014248956,0.003640646,0.64798486,0.00018503603,0.00078106957,0.000019360228,0.0005923316,0.0016724843,0.13114432,0.0036535093,0.19563681,0.00044062277],"about_ca_topic_score_codex":0.000020823974,"about_ca_topic_score_gemma":0.0000025096735,"teacher_disagreement_score":0.5268521,"about_ca_system_score_codex":0.00013135678,"about_ca_system_score_gemma":0.000052598567,"threshold_uncertainty_score":0.3870691},"labels":[],"label_agreement":null},{"id":"W2100520373","doi":"10.1016/j.biologicals.2011.02.001","title":"Three Rs approaches in the production and quality control of fish vaccines","year":2011,"lang":"en","type":"article","venue":"Biologicals","topic":"Aquaculture disease management and microbiota","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Novartis (Canada); Health Canada; Canadian Council on Animal Care","funders":"","keywords":"Quality (philosophy); Fish <Actinopterygii>; Vaccination; Animal welfare; Business; Production (economics); Biotechnology; Control (management); Animal testing; Risk analysis (engineering); Toxicology; Computer science; Medicine; Biology; Fishery; Immunology; Ecology","score_opus":0.1164029874476921,"score_gpt":0.2631066938941076,"score_spread":0.1467037064464155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2100520373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955971,0.0016736399,0.000094234776,0.00063951145,0.00010671753,0.0004524392,0.000025054522,0.000020688129,0.0013905619],"genre_scores_gemma":[0.99943525,0.000055913988,0.000029301349,0.0002879539,0.00001592335,0.000028404475,0.000028399385,0.0000019635174,0.000116906354],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992383,0.00021909238,0.00020262072,0.00019780974,0.000011018214,0.00013112136],"domain_scores_gemma":[0.99964523,0.00007713354,0.000094726056,0.00015956703,0.000018054454,0.000005312716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005559421,0.00009133797,0.00018821926,0.000026948037,0.000045587683,0.0000033679348,0.00015198105,0.00011972365,0.00012811509],"category_scores_gemma":[0.00022859349,0.000045208486,0.00004360845,0.0000700137,0.00017474685,0.000029011357,0.000039370265,0.00007994943,0.000013019541],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011669961,0.0011175771,0.48267117,0.00011165954,0.0003477898,0.0000028738905,0.0028007168,5.7910495e-7,0.4401079,0.046302613,0.013578381,0.011791727],"study_design_scores_gemma":[0.0005577513,0.00013142139,0.98487884,0.000015173445,0.00004420789,0.0000042649053,0.0010445768,2.5353006e-7,0.008070857,0.0010523378,0.004086255,0.00011406189],"about_ca_topic_score_codex":0.00006568564,"about_ca_topic_score_gemma":0.000129983,"teacher_disagreement_score":0.5022077,"about_ca_system_score_codex":0.0000029276298,"about_ca_system_score_gemma":0.0000033582114,"threshold_uncertainty_score":0.18435486},"labels":[],"label_agreement":null},{"id":"W2120786830","doi":"10.1016/j.biologicals.2005.06.007","title":"The effect of solvent environment on the conformation and stability of human polyclonal IgG in solution","year":2005,"lang":"en","type":"article","venue":"Biologicals","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Prairie Oat Growers Association; Agence Nationale pour la Gestion des Déchets Radioactifs; Hungarian Scientific Research Fund; Teva Pharmaceutical Industries","keywords":"Sorbitol; Chemistry; Conformational change; Denaturation (fissile materials); Maltose; Monomer; Thermal stability; Solvent; Sucrose; Biophysics; Chromatography; Organic chemistry; Biochemistry; Polymer; Nuclear chemistry","score_opus":0.0167142682739987,"score_gpt":0.25720191343629795,"score_spread":0.24048764516229926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120786830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981033,0.00064342766,0.00007384941,0.00057075726,0.0000070329716,0.00031525068,0.000010955792,0.0000014618618,0.0002739582],"genre_scores_gemma":[0.9997539,0.00012783543,0.000017949102,0.00002957293,0.000011841083,0.00003376704,0.000016604208,9.65949e-7,0.000007586538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993426,0.00022844023,0.00020025493,0.00010119194,0.000056286462,0.00007118766],"domain_scores_gemma":[0.99961746,0.000083252446,0.00009019248,0.00018717472,0.000008932283,0.000013012517],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001025275,0.000051747782,0.00007532738,0.000005687581,0.000055784887,0.0000021852563,0.000077035285,0.00006269175,0.000026529575],"category_scores_gemma":[0.00014379868,0.000023891303,0.00003363208,0.000014455207,0.00022678444,0.0000013076312,0.000038717077,0.000039177005,0.0000013522205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016596571,0.000056995195,0.017667156,0.000008455528,0.0000065545482,1.07199005e-8,0.000025932155,0.0000046114583,0.9713476,0.0010760975,0.000022048378,0.009618603],"study_design_scores_gemma":[0.00021191243,0.00078712654,0.1376423,0.0000031307818,0.000002000447,2.1208979e-7,0.000021420914,0.000054475353,0.8578803,0.00011756877,0.0032450145,0.000034550158],"about_ca_topic_score_codex":0.000006162046,"about_ca_topic_score_gemma":0.000008176991,"teacher_disagreement_score":0.119975135,"about_ca_system_score_codex":0.00001098349,"about_ca_system_score_gemma":0.000004742093,"threshold_uncertainty_score":0.09742591},"labels":[],"label_agreement":null},{"id":"W2124287269","doi":"10.1016/j.biologicals.2012.07.005","title":"Report on the international workshop on alternative methods for human and veterinary rabies vaccine testing: State of the science and planning the way forward","year":2012,"lang":"en","type":"article","venue":"Biologicals","topic":"Rabies epidemiology and control","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Rabies; Potency; Rabies virus; Rabies vaccine; Medicine; Vaccination; Veterinary medicine; Virology; Test (biology); Human use; Biotechnology; Biology; In vitro","score_opus":0.1690479999700361,"score_gpt":0.41720956290237615,"score_spread":0.24816156293234004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124287269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927105,0.0012010986,0.0004952542,0.0038601672,0.000584905,0.00038358182,0.000011815093,0.000013716277,0.000738989],"genre_scores_gemma":[0.9980221,0.00002937695,0.0003335102,0.0011501731,0.000061993785,0.00008194525,0.0000034250922,0.0000034048123,0.00031409605],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986966,0.00054272346,0.00025993804,0.00022419625,0.000030173898,0.00024631704],"domain_scores_gemma":[0.99215096,0.007220787,0.00027431542,0.00023205219,0.00010769869,0.000014204483],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.004966485,0.00011613969,0.00021012056,0.000031527306,0.0005733762,0.000010958869,0.0003958927,0.00008381938,0.000014527594],"category_scores_gemma":[0.010605529,0.000042433487,0.00004319563,0.00007365658,0.0009774929,0.00004006042,0.00023830995,0.00021901302,0.0000014036073],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086818036,0.00011060202,0.057112604,0.000007817773,0.00032392118,0.0000023315106,0.0010061276,0.000048448564,0.8500083,0.027717417,0.0016844551,0.06110981],"study_design_scores_gemma":[0.0012130281,0.0015228709,0.83057225,0.0001440484,0.000066252025,0.0003043323,0.0007864424,0.00014946015,0.09274197,0.028840981,0.04338365,0.00027474147],"about_ca_topic_score_codex":0.0000068627673,"about_ca_topic_score_gemma":3.5405387e-7,"teacher_disagreement_score":0.7734596,"about_ca_system_score_codex":0.000015039181,"about_ca_system_score_gemma":0.000012883515,"threshold_uncertainty_score":0.9977286},"labels":[],"label_agreement":null},{"id":"W2173702989","doi":"10.1016/j.biologicals.2015.09.001","title":"Reverse vaccinology as an approach for developing Histophilus somni vaccine candidates","year":2015,"lang":"en","type":"article","venue":"Biologicals","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Health; University of Saskatchewan","funders":"Alberta Livestock and Meat Agency","keywords":"Reverse vaccinology; Biology; Genome; Antigen; Antigenicity; Microbiology; Bacteria; Whole genome sequencing; Pathogen; Vaccination; Gene; Virology; Computational biology; Genetics","score_opus":0.08899190730983174,"score_gpt":0.3403462491360139,"score_spread":0.25135434182618216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2173702989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97196704,0.00664833,0.0130700385,0.0021118799,0.0008948694,0.0013803586,0.00014400737,0.0003751403,0.003408329],"genre_scores_gemma":[0.9860288,0.00016300596,0.0046899524,0.0009544967,0.00020026314,0.00012863129,0.0012257778,0.000019342462,0.0065897354],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99848086,0.00024441813,0.0002776753,0.00046699247,0.000022201673,0.00050786074],"domain_scores_gemma":[0.99922204,0.00010828775,0.00008234975,0.0002909767,0.00017446655,0.00012188067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042769825,0.0001888566,0.00034474378,0.00012352371,0.00020840614,0.000021231857,0.00026729502,0.00042383064,0.00046359058],"category_scores_gemma":[0.0005208771,0.00013564042,0.00009457788,0.00014786856,0.0000884036,0.00008251254,0.00012895896,0.00016868836,0.00056239933],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023752633,0.00083647174,0.0069002705,0.00005041157,0.00033881125,0.000013572715,0.0002476852,0.000026201984,0.6334353,0.045477048,0.29881132,0.0114876395],"study_design_scores_gemma":[0.007886972,0.0026603842,0.0029895112,0.000019057477,0.00009638051,0.0004198125,0.0004889776,0.000042235526,0.07073018,0.02189513,0.8918457,0.0009256465],"about_ca_topic_score_codex":0.0005812581,"about_ca_topic_score_gemma":0.00002366451,"teacher_disagreement_score":0.5930344,"about_ca_system_score_codex":0.00012615848,"about_ca_system_score_gemma":0.00036066934,"threshold_uncertainty_score":0.72286934},"labels":[],"label_agreement":null},{"id":"W2302865716","doi":"10.1016/j.biologicals.2016.02.001","title":"Support for the revocation of general safety test regulations in biologics license applications","year":2016,"lang":"en","type":"article","venue":"Biologicals","topic":"Immunotoxicology and immune responses","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pfizer (Canada)","funders":"Pfizer","keywords":"Adjuvant; Toxicity; Food and drug administration; Pharmacology; Medicine; Test (biology); Immune system; Biology; Immunology; Internal medicine","score_opus":0.02577668538105677,"score_gpt":0.2891273630291305,"score_spread":0.26335067764807374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2302865716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89778644,0.017449608,0.052541893,0.017072275,0.0012498123,0.008466062,0.0018203786,0.00031749313,0.0032960179],"genre_scores_gemma":[0.99207455,0.0011934987,0.00040646238,0.0002122113,0.000032619922,0.00070486765,0.00013859138,0.000006451697,0.0052307528],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986919,0.0002698186,0.00050571136,0.00024290092,0.000014988183,0.00027465227],"domain_scores_gemma":[0.9946949,0.0045909174,0.00021350103,0.00038212902,0.00010983083,0.00000875101],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008288582,0.00012915478,0.00025974752,0.00007561537,0.0002155156,0.0000029346215,0.00030856373,0.00038197677,0.0004127671],"category_scores_gemma":[0.0014462228,0.00006032577,0.00011003058,0.00017973394,0.00063155533,0.00003990028,0.00007016872,0.000095351315,0.00012300361],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039158933,0.00018682318,0.008621328,0.0000045691318,0.000044052715,1.3065406e-7,0.000028144514,0.000003306125,0.94793236,0.016962402,0.0010421113,0.024783187],"study_design_scores_gemma":[0.0015221374,0.00070982345,0.42355365,0.000023407487,0.000035661178,0.000023474593,0.00007068875,0.0000036967222,0.16575167,0.0019911607,0.40612727,0.00018734577],"about_ca_topic_score_codex":0.00001280293,"about_ca_topic_score_gemma":0.000008045001,"teacher_disagreement_score":0.78218067,"about_ca_system_score_codex":0.000035663943,"about_ca_system_score_gemma":0.000065157445,"threshold_uncertainty_score":0.45195103},"labels":[],"label_agreement":null},{"id":"W2342581896","doi":"10.1016/j.biologicals.2016.03.006","title":"Switching to biosimilar infliximab (CT-P13): Evidence of clinical safety, effectiveness and impact on public health","year":2016,"lang":"en","type":"review","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biosimilar; Infliximab; Medicine; Public health; Intensive care medicine; Internal medicine; Pathology; Disease","score_opus":0.3128732576127962,"score_gpt":0.5311404830159735,"score_spread":0.21826722540317728,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2342581896","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010120148,0.99482495,0.00034750215,0.001162961,0.0006212369,0.0014992729,0.00035495698,0.00006838168,0.00010874521],"genre_scores_gemma":[0.008792261,0.9897298,0.0003405392,0.00086536945,0.00011439496,0.00005812127,0.000022140483,0.000030192045,0.000047156995],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9870169,0.008679417,0.0021482755,0.0012076378,0.00008271605,0.00086505734],"domain_scores_gemma":[0.98413855,0.013653951,0.0010724976,0.00074501894,0.000113059454,0.0002769289],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0107166255,0.0007517555,0.005522726,0.00029056618,0.00018819253,0.000030649808,0.0007185815,0.0011580536,0.00038404984],"category_scores_gemma":[0.006730298,0.00033669308,0.0012140425,0.00043702888,0.0005248542,0.00006236429,0.0005862455,0.0009222496,0.00019640443],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020557735,0.00019977336,0.00032623575,0.0021419488,0.0005525938,0.0000051581915,0.000004400147,3.0529357e-8,0.00020039824,0.0003969586,0.00043971193,0.9955272],"study_design_scores_gemma":[0.0005557043,0.0043212087,0.005314175,0.028498562,0.00017454562,0.00007162812,0.0000036638603,1.3259428e-7,0.00007344166,0.00013613387,0.9603161,0.0005347115],"about_ca_topic_score_codex":0.000019318437,"about_ca_topic_score_gemma":0.0000010911009,"teacher_disagreement_score":0.9949925,"about_ca_system_score_codex":0.00016691096,"about_ca_system_score_gemma":0.00046465528,"threshold_uncertainty_score":0.9999085},"labels":[],"label_agreement":null},{"id":"W2440811431","doi":"10.1016/j.biologicals.2016.04.007","title":"Where are we in our understanding of the association between narcolepsy and one of the 2009 adjuvanted influenza A (H1N1) vaccines?","year":2016,"lang":"en","type":"article","venue":"Biologicals","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"World Health Organization","keywords":"Narcolepsy; Pandemic; Medicine; Influenza vaccine; Epidemiology; Vaccination; Cataplexy; H1N1 influenza; Adverse effect; Immunology; Family medicine; Coronavirus disease 2019 (COVID-19); Psychiatry; Modafinil; Internal medicine; Disease","score_opus":0.17655188406803426,"score_gpt":0.3462955659315847,"score_spread":0.16974368186355046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2440811431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920051,0.00017840536,0.00003976315,0.0072071357,0.00004483345,0.00028919804,0.00007066818,0.000009437853,0.00015542943],"genre_scores_gemma":[0.9994739,0.00025225186,0.0000039873107,0.00010777898,0.000026488577,0.000009456722,9.204519e-8,0.0000036503293,0.00012237669],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99855953,0.00054521125,0.00024721283,0.00019318436,0.00025177232,0.00020310062],"domain_scores_gemma":[0.99863005,0.0008362271,0.000274638,0.00019137542,0.00004023041,0.000027470522],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005440634,0.00007592416,0.00021035907,0.000046843514,0.000076997676,0.00001043286,0.00031654304,0.00012837448,0.000022135022],"category_scores_gemma":[0.002523973,0.000029923985,0.000051210794,0.00041668199,0.00007544484,0.00005262138,0.0001964862,0.000116470066,0.0000023185323],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027122825,0.000033595556,0.84178424,0.000014247991,0.000006452617,3.2489118e-7,0.00004385145,8.333362e-7,0.15646689,0.0006053343,0.0001089341,0.0009081585],"study_design_scores_gemma":[0.0006703332,0.00006456088,0.8906248,0.00030075063,0.0000071687723,3.7304258e-7,0.00026107708,0.000005092435,0.10336013,0.0044262684,0.00021911053,0.000060286795],"about_ca_topic_score_codex":0.000015080967,"about_ca_topic_score_gemma":0.000042155,"teacher_disagreement_score":0.053106748,"about_ca_system_score_codex":0.000090843554,"about_ca_system_score_gemma":0.00002531571,"threshold_uncertainty_score":0.30216134},"labels":[],"label_agreement":null},{"id":"W2496582177","doi":"10.1016/j.biologicals.2016.06.002","title":"Report of the International Regulatory Forum on Human Cell Therapy and Gene Therapy Products","year":2016,"lang":"en","type":"article","venue":"Biologicals","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Japan Agency for Medical Research and Development","keywords":"Regulatory agency; Agency (philosophy); Quality (philosophy); Regulatory science; Regulatory authority; Business; Political science; Medicine; Public relations; Public administration; Pathology; Sociology","score_opus":0.08972948811793831,"score_gpt":0.33040383325975975,"score_spread":0.24067434514182146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2496582177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94686276,0.0005240062,0.000009985327,0.05118252,0.00018916595,0.00023743702,0.0000040820796,0.000014824904,0.0009752159],"genre_scores_gemma":[0.99604654,0.00077756017,0.0001154105,0.0012291161,0.00017730275,0.0000067764745,0.0000074575023,0.000004545704,0.0016352846],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992892,0.00003808388,0.00019432655,0.00019276029,0.0002013649,0.00008426622],"domain_scores_gemma":[0.9994512,0.00004796854,0.00012977996,0.00024452346,0.00009123741,0.000035287238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003848006,0.000067859066,0.00012310292,0.000023438462,0.00004515788,0.0000031226602,0.00008457228,0.00014862152,0.00007679254],"category_scores_gemma":[0.00007618835,0.000022821325,0.000046573707,0.000048314647,0.0005153918,0.00001097226,0.000034072717,0.0000664977,0.0000015720167],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008562582,0.00014832312,0.0100898165,0.000003848226,0.000020616684,0.0000038167263,0.000016145623,2.4166612e-8,0.95240927,0.0031548315,0.0009958132,0.03307187],"study_design_scores_gemma":[0.0010816182,0.00043300245,0.49658036,0.000043582815,0.0000026332675,0.000026584157,0.000005801102,9.69615e-7,0.44122145,0.004084066,0.05647161,0.000048330712],"about_ca_topic_score_codex":0.0000030069593,"about_ca_topic_score_gemma":2.8990786e-7,"teacher_disagreement_score":0.5111878,"about_ca_system_score_codex":0.000013095403,"about_ca_system_score_gemma":0.00003153326,"threshold_uncertainty_score":0.18989825},"labels":[],"label_agreement":null},{"id":"W2592281295","doi":"10.1016/j.biologicals.2017.01.006","title":"The impact of oxidative DNA changes and ATM expression on morphological and functional activities on hepatocytes obtained from mesenchymal stem cells","year":2017,"lang":"en","type":"article","venue":"Biologicals","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nutrasource","funders":"Iran National Science Foundation","keywords":"Mesenchymal stem cell; Cell biology; Cellular differentiation; Oxidative phosphorylation; Biology; Reactive oxygen species; Stem cell; Progenitor cell; Molecular biology; Chemistry; Biochemistry; Gene","score_opus":0.039182796231659135,"score_gpt":0.29635522549772214,"score_spread":0.257172429266063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2592281295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987074,0.00041014314,0.000031650947,0.00021251726,0.000053482876,0.0001868028,0.00020165923,0.0000051964134,0.00019110682],"genre_scores_gemma":[0.9988062,0.00076801097,0.00006476945,0.000059254737,0.00012623282,0.000023329465,0.00003064366,0.0000047795374,0.000116823],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991982,0.0001187239,0.00010633156,0.00032353264,0.00008886634,0.00016435976],"domain_scores_gemma":[0.99926955,0.00018886534,0.00015473475,0.000296059,0.000029191802,0.00006158117],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014497235,0.00015824907,0.00018910985,0.000012301222,0.00033278597,0.00005138328,0.00011743156,0.00016919123,0.00002434079],"category_scores_gemma":[0.000059055386,0.00007723703,0.00007507055,0.00000997123,0.0003251418,0.0000032163166,0.00021158744,0.00007214631,0.0000011400788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006054904,0.00006186242,0.009704492,0.0000018564277,0.000050833423,0.0000035363648,0.000016477179,0.000006258239,0.9852649,0.00006714522,0.0002913737,0.0039257593],"study_design_scores_gemma":[0.00028561786,0.001680527,0.25037166,0.000011962949,0.000005770388,0.0000029803923,0.00011241844,0.000019611956,0.7470382,0.00012831125,0.00025047277,0.00009250426],"about_ca_topic_score_codex":0.000056444598,"about_ca_topic_score_gemma":0.000013885589,"teacher_disagreement_score":0.24066716,"about_ca_system_score_codex":0.000011803239,"about_ca_system_score_gemma":0.000015667809,"threshold_uncertainty_score":0.31496346},"labels":[],"label_agreement":null},{"id":"W2622615271","doi":"10.1016/j.biologicals.2017.05.006","title":"Modern science for better quality control of medicinal products “Towards global harmonization of 3Rs in biologicals”: The report of an EPAA workshop","year":2017,"lang":"en","type":"article","venue":"Biologicals","topic":"Diphtheria, Corynebacterium, and Tetanus","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Joint Research Centre; Directorate-General for the Environment; European Federation of Pharmaceutical Industries and Associations; World Health Organization; National Centre for the Replacement Refinement and Reduction of Animals in Research; European Commission; European Partnership for Alternative Approaches to Animal Testing","keywords":"Harmonization; Good laboratory practice; Quality (philosophy); General partnership; Business; Agency (philosophy); Biotechnology; Medicine; Political science; Quality assurance; Marketing; Biology; Law","score_opus":0.06057264648608483,"score_gpt":0.3716940175364104,"score_spread":0.31112137105032556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2622615271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941708,0.00028615855,0.0039607617,0.0005727351,0.00014915729,0.0004467532,0.00010300067,0.0000046938267,0.00030594636],"genre_scores_gemma":[0.99855936,0.00003761527,0.0010819797,0.00010792396,0.000105626255,0.000027081593,0.000056555204,0.0000038152284,0.0000200473],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99849695,0.00015014248,0.00055170496,0.0004308306,0.00015290978,0.00021744039],"domain_scores_gemma":[0.99801546,0.00004433706,0.0007110395,0.000771988,0.0004125249,0.000044634577],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019117623,0.00012767377,0.00036210185,0.00001901322,0.00009443374,0.000014847111,0.00066834816,0.00017534052,0.000006716639],"category_scores_gemma":[0.0043135835,0.00007061043,0.00008196249,0.00008963707,0.0014924009,0.000011039573,0.00013333921,0.0000448318,1.5136514e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039131084,0.00015842245,0.035881814,0.00002207839,0.000023218168,0.0000022599586,0.000026683438,0.000009208268,0.94703054,0.0002520436,0.000011966589,0.016190436],"study_design_scores_gemma":[0.0010347059,0.0009023517,0.5460161,0.000030099,0.000025498613,0.00001599057,0.000074943935,0.00012042247,0.44888246,0.0022502432,0.0004868527,0.00016030978],"about_ca_topic_score_codex":0.000040641815,"about_ca_topic_score_gemma":0.000016691924,"teacher_disagreement_score":0.5101343,"about_ca_system_score_codex":0.0000110659885,"about_ca_system_score_gemma":0.00013658912,"threshold_uncertainty_score":0.5498813},"labels":[],"label_agreement":null},{"id":"W2625442506","doi":"10.1016/j.biologicals.2017.06.001","title":"A demonstration of analytical similarity comparing a proposed biosimilar pegfilgrastim and reference pegfilgrastim","year":2017,"lang":"en","type":"article","venue":"Biologicals","topic":"Neutropenia and Cancer Infections","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Pegfilgrastim; Biosimilar; Similarity (geometry); Medicine; Computer science; Pharmacology; Filgrastim; Internal medicine; Artificial intelligence; Granulocyte colony-stimulating factor; Chemotherapy","score_opus":0.14107235592230905,"score_gpt":0.3735971690895813,"score_spread":0.23252481316727225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2625442506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98106146,0.000077557255,0.00034691562,0.0011896725,0.000047691497,0.0003185406,0.00001768703,0.000044321314,0.016896153],"genre_scores_gemma":[0.9988089,0.00009344779,0.00077329256,0.00011714086,0.00005355356,0.000011389951,0.000014811756,0.0000048572724,0.0001225675],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99912554,0.000045363347,0.00025821553,0.00027761448,0.00011598622,0.00017726737],"domain_scores_gemma":[0.9991934,0.000060807855,0.0001644882,0.00033737725,0.00011266058,0.00013127264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019043454,0.0001266798,0.00039206995,0.000046918572,0.0002172961,0.00004405076,0.00011312566,0.00014022137,0.00009311682],"category_scores_gemma":[0.0002751258,0.00008574764,0.0000649343,0.00005621413,0.00048040325,0.00006431686,0.000089726,0.00018549511,0.0000075888347],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029678238,0.00023357065,0.92638296,0.00007724009,0.00006731432,0.000018546074,0.000024052219,0.0000024552376,0.06486344,0.005049977,0.0004448515,0.0025388065],"study_design_scores_gemma":[0.0008599765,0.0007041555,0.9883314,0.000082189836,0.00013116372,0.00005175698,0.000031016774,0.0009180864,0.007391292,0.00039692028,0.0009786076,0.00012343976],"about_ca_topic_score_codex":0.000054395263,"about_ca_topic_score_gemma":0.000030851545,"teacher_disagreement_score":0.061948434,"about_ca_system_score_codex":0.000019630686,"about_ca_system_score_gemma":0.00005848596,"threshold_uncertainty_score":0.34966874},"labels":[],"label_agreement":null},{"id":"W2779036013","doi":"10.1016/j.biologicals.2017.12.002","title":"WHO informal consultation on development of guidelines on procedures and data requirements for changes to approved biotherapeutic products, Seoul, Republic of Korea, 27–28 April 2017","year":2017,"lang":"en","type":"article","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Ministry of Food and Drug Safety; World Health Organization","keywords":"Harmonization; Standardization; Authorization; Licensure; Business; Quality (philosophy); Medicine; Public consultation; Medical education; Computer science; Engineering; Computer security","score_opus":0.3204473695739347,"score_gpt":0.4391512621598847,"score_spread":0.11870389258594999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2779036013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.963909,0.0029268642,0.0010300138,0.025313593,0.0008165137,0.0036957671,0.0011570666,0.00007003742,0.0010811603],"genre_scores_gemma":[0.88050896,0.0010909527,0.10688557,0.00594486,0.00017741314,0.0001751619,0.00070583867,0.000027027676,0.004484192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987253,0.00006767599,0.0004850936,0.00044022547,0.00004716746,0.0002345533],"domain_scores_gemma":[0.99832916,0.00018712544,0.00045239844,0.0006730089,0.00033045057,0.000027843816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001186589,0.00017075265,0.00039958605,0.000079976984,0.00019725204,0.000022979193,0.0005310012,0.00025853497,0.000020282403],"category_scores_gemma":[0.0057438915,0.00010164776,0.00002541907,0.000052736737,0.00032811213,0.00006345075,0.0002658241,0.00006935794,0.000003822641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017007744,0.00029650016,0.0014865604,0.00029969524,0.0003294212,2.653968e-7,0.00025214578,3.2685895e-7,0.7572313,0.0014873053,0.01907743,0.21783827],"study_design_scores_gemma":[0.0015817747,0.0022301823,0.045841042,0.00030930157,0.000058608915,0.0000032946396,0.00012056642,0.000020079377,0.59747744,0.00015124092,0.35191217,0.00029432337],"about_ca_topic_score_codex":0.000007784883,"about_ca_topic_score_gemma":0.000020738738,"teacher_disagreement_score":0.33283475,"about_ca_system_score_codex":0.000008629954,"about_ca_system_score_gemma":0.00007804469,"threshold_uncertainty_score":0.68763894},"labels":[],"label_agreement":null},{"id":"W2806244397","doi":"10.1016/j.biologicals.2018.05.006","title":"Host cell protein testing strategy for hepatitis B antigen in Hexavalent vaccine – Towards a general testing strategy for recombinant vaccines","year":2018,"lang":"en","type":"article","venue":"Biologicals","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Virology; Recombinant DNA; Antigen; Biology; Immunology; Gene; Biochemistry","score_opus":0.15399945393424844,"score_gpt":0.35258786534686404,"score_spread":0.1985884114126156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806244397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918412,0.0008283567,0.00054345484,0.00050858833,0.00020931562,0.004382225,0.0001423018,0.00017602454,0.0013685607],"genre_scores_gemma":[0.9624603,0.00017822259,0.034203224,0.0002667391,0.0008681779,0.0012293534,0.000063616804,0.00004659385,0.0006837964],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971852,0.00011409864,0.00088486355,0.0007600495,0.00015908823,0.0008967351],"domain_scores_gemma":[0.99793917,0.0005249024,0.00030098963,0.0003067621,0.000764232,0.00016395672],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00085755496,0.00041231405,0.0008970134,0.0001406498,0.00026847265,0.000047664682,0.00019851833,0.00025652067,0.00007383436],"category_scores_gemma":[0.0039064065,0.0002913162,0.00013570159,0.00043984764,0.00007689394,0.00008346126,0.00012517897,0.00017042134,0.000020709804],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035858637,0.00050998485,0.7276911,0.00042336766,0.00006200151,0.00004460289,0.000079323785,0.000013418399,0.22138579,0.00015227038,0.0013838842,0.04789565],"study_design_scores_gemma":[0.003795514,0.014190087,0.9295134,0.0005053791,0.000058519978,0.0000257077,0.000059126527,0.0037377377,0.043559086,0.00140363,0.0026021637,0.000549657],"about_ca_topic_score_codex":0.003710185,"about_ca_topic_score_gemma":0.001736345,"teacher_disagreement_score":0.20182228,"about_ca_system_score_codex":0.0001308257,"about_ca_system_score_gemma":0.00022495353,"threshold_uncertainty_score":0.9999539},"labels":[],"label_agreement":null},{"id":"W2809322123","doi":"10.1016/j.biologicals.2018.06.001","title":"First evaluation of endotoxins in veterinary autogenous vaccines produced in Italy by LAL assay","year":2018,"lang":"en","type":"article","venue":"Biologicals","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Health, British Columbia","keywords":"Veterinary medicine; Medicine; Microbiology; Biology","score_opus":0.07382721005317615,"score_gpt":0.3508914496349961,"score_spread":0.2770642395818199,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809322123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965632,0.0018999282,0.000009978464,0.00013544508,0.00014943293,0.000520103,0.00006618032,0.00002250756,0.0006332173],"genre_scores_gemma":[0.999547,0.000085898486,0.000015604326,0.000027752512,0.000027796495,0.00008568522,0.00009714223,0.000004636737,0.00010846412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984012,0.0007109507,0.00029735145,0.00027990306,0.0000359206,0.000274643],"domain_scores_gemma":[0.9994376,0.00014560916,0.00006596812,0.0001876214,0.00014708549,0.000016120754],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014645202,0.00010420572,0.00022356692,0.00014635047,0.00006693511,0.000005814327,0.00012994876,0.0002118767,0.0016137918],"category_scores_gemma":[0.00064835564,0.00007720455,0.000047746013,0.00025758066,0.00017006604,0.000040318282,0.000085653934,0.00011771667,0.00019450477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015749669,0.0005089717,0.02199524,0.000011691971,0.000020494834,0.0000019960546,0.00006218521,0.000005846856,0.9733294,0.00006328887,0.0010590294,0.0027843437],"study_design_scores_gemma":[0.004619223,0.0032106014,0.23736306,0.0001068088,0.000036327263,0.000062896914,0.00011695265,0.00010637608,0.7179889,0.00074343494,0.035225604,0.00041983288],"about_ca_topic_score_codex":0.00033430866,"about_ca_topic_score_gemma":0.00013775735,"teacher_disagreement_score":0.25534052,"about_ca_system_score_codex":0.000071909555,"about_ca_system_score_gemma":0.000075889635,"threshold_uncertainty_score":0.9992989},"labels":[],"label_agreement":null},{"id":"W2886053403","doi":"10.1016/j.biologicals.2018.08.002","title":"Report of the international conference on next generation sequencing for adventitious virus detection in biologicals","year":2018,"lang":"en","type":"article","venue":"Biologicals","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"World Health Organization","keywords":"Standardization; Harmonization; Food and drug administration; Biotechnology; Product (mathematics); Medicine; Risk analysis (engineering); Computer science; Biology","score_opus":0.24971553877288072,"score_gpt":0.31916708154652623,"score_spread":0.06945154277364551,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886053403","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99638337,0.000027605744,0.00007821386,0.0005420649,0.0004223528,0.00033434504,0.000043834538,0.000033333872,0.002134894],"genre_scores_gemma":[0.99890375,0.00006880466,0.00011544822,0.00026524355,0.0004457774,0.00008441424,0.000020194162,5.0856727e-7,0.00009586111],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990824,0.00008615273,0.000312109,0.00027430948,0.000095750984,0.00014932],"domain_scores_gemma":[0.99940425,0.00014291624,0.00019601248,0.000058600566,0.00018027876,0.000017950075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040877677,0.00009814425,0.0001485083,0.000014552248,0.0002125744,0.000024003803,0.00020291792,0.00012114583,0.0002596591],"category_scores_gemma":[0.0006701612,0.00003070147,0.000098116754,0.0001881111,0.00019679152,0.00004840129,0.000086057495,0.000067809786,0.000014370252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033331213,0.000045377623,0.002985471,8.468554e-7,0.00000770177,8.6093314e-7,0.000011539094,0.000002372784,0.9857338,0.0014338989,0.00010376756,0.00964105],"study_design_scores_gemma":[0.00023263381,0.002380209,0.16772458,0.00004623212,0.0000120896075,0.000034180815,0.00029145658,0.0012479565,0.80941564,0.007441325,0.010907193,0.00026653524],"about_ca_topic_score_codex":0.00022686683,"about_ca_topic_score_gemma":0.0022779172,"teacher_disagreement_score":0.17631817,"about_ca_system_score_codex":0.00007208418,"about_ca_system_score_gemma":0.000007632205,"threshold_uncertainty_score":0.2843085},"labels":[],"label_agreement":null},{"id":"W2888360525","doi":"10.1016/j.biologicals.2018.08.004","title":"Report of the international conference on manufacturing and testing of pluripotent stem cells","year":2018,"lang":"en","type":"article","venue":"Biologicals","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stemcell Technologies; Health Canada","funders":"National Institutes of Health; Comissão Interministerial para os Recursos do Mar; Novo Nordisk Fonden; World Health Organization","keywords":"Induced pluripotent stem cell; Biology; Genetics; Embryonic stem cell","score_opus":0.06820956123313249,"score_gpt":0.29827132824895236,"score_spread":0.23006176701581987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888360525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948092,0.00004256055,0.00004746787,0.00014550997,0.00011173766,0.00011787841,0.000015877751,0.0000032355028,0.0047065453],"genre_scores_gemma":[0.99881494,0.00005028852,0.0003291919,0.000045792236,0.00007138464,0.0000035957517,0.0000039315523,0.00000331489,0.00067756744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999289,0.000049892897,0.00020307927,0.00021533786,0.00013376868,0.00010892271],"domain_scores_gemma":[0.99943507,0.000030116982,0.00015247913,0.00023045475,0.00012373805,0.000028115594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027111694,0.00006972434,0.00009948081,0.00001661623,0.000033004373,0.000006348494,0.00025093512,0.00007827741,0.000025173293],"category_scores_gemma":[0.00009831528,0.000040095423,0.000037659785,0.000027170221,0.00024525018,0.0000010548919,0.00031241833,0.000048155685,0.00000244216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003206727,0.000025604542,0.0040295618,0.00000926587,0.000017614211,0.0000030813064,0.000005130635,0.0000042161564,0.99330854,0.00005517747,0.00010879306,0.002400956],"study_design_scores_gemma":[0.00010583089,0.0002793572,0.012453526,0.00002831902,0.0000025207507,0.000021958038,0.000017914517,0.0000508646,0.98462105,0.00006544907,0.0023063642,0.00004681782],"about_ca_topic_score_codex":0.0000090258,"about_ca_topic_score_gemma":0.000001798611,"teacher_disagreement_score":0.008687454,"about_ca_system_score_codex":0.0000054709913,"about_ca_system_score_gemma":0.000024619112,"threshold_uncertainty_score":0.16350439},"labels":[],"label_agreement":null},{"id":"W2947532070","doi":"10.1016/j.biologicals.2019.05.002","title":"Octanorm [cutaquig®], a new immunoglobulin (human) subcutaneous 16.5% solution for injection (165 mg/mL) – Biochemical characterization, pathogen safety, and stability","year":2019,"lang":"en","type":"article","venue":"Biologicals","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Antibody; Immune system; Immunoglobulin G; Titer; Chemistry; Subcutaneous injection; Manufacturing process; Immunology; Medicine; Materials science; Internal medicine","score_opus":0.012981846083599938,"score_gpt":0.2285992981866764,"score_spread":0.21561745210307648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947532070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98593265,0.0075790538,0.0034371614,0.0003002425,0.0007153349,0.0011653997,0.0002593024,0.0001852991,0.00042556747],"genre_scores_gemma":[0.9946986,0.00028484716,0.000052425174,0.00020873899,0.000020152873,0.00003919392,0.0029759852,0.000018499934,0.0017015529],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979069,0.00020975988,0.00063572003,0.000655544,0.00003930269,0.0005527683],"domain_scores_gemma":[0.99903744,0.00018227035,0.00025655652,0.00039026293,0.00011350333,0.000019988369],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005003428,0.00031441275,0.000503369,0.000074340765,0.00041484385,0.000035867,0.00026509695,0.0006528697,0.0010160252],"category_scores_gemma":[0.00020564829,0.0002557593,0.00017020016,0.00017964658,0.00029074764,0.0001198853,0.0001579228,0.00024644117,0.00024874727],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001060199,0.00017208797,0.0018293961,0.000029226081,0.000061571234,4.849201e-7,0.00020009906,7.9127335e-7,0.9789081,0.0008276591,0.00007640606,0.016833944],"study_design_scores_gemma":[0.0129109165,0.009003336,0.16851348,0.00022001007,0.00029474412,0.00087625755,0.0012649961,0.00015573883,0.3541359,0.0071288995,0.44250384,0.002991869],"about_ca_topic_score_codex":0.00013889969,"about_ca_topic_score_gemma":0.000003394517,"teacher_disagreement_score":0.62477225,"about_ca_system_score_codex":0.00011383328,"about_ca_system_score_gemma":0.00007625718,"threshold_uncertainty_score":0.99998945},"labels":[],"label_agreement":null},{"id":"W2953443439","doi":"10.1016/j.biologicals.2019.06.005","title":"Achieving scientific and regulatory success in implementing non-animal approaches to human and veterinary rabies vaccine testing: A NICEATM and IABS workshop report","year":2019,"lang":"en","type":"article","venue":"Biologicals","topic":"Rabies epidemiology and control","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"National Institute of Environmental Health Sciences; National Institutes of Health; Erzincan Üniversitesi; European Commission; Boehringer Ingelheim; U.S. Department of Agriculture","keywords":"Potency; Rabies vaccine; Rabies; Test (biology); Medicine; Government (linguistics); Veterinary medicine; Biotechnology; Rabies virus; Virology; Biology; In vitro","score_opus":0.13282198521807548,"score_gpt":0.3131334991516462,"score_spread":0.1803115139335707,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953443439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99459374,0.0036442273,0.000007907218,0.0006429293,0.000126115,0.0005594165,0.0000062949325,0.000048903457,0.00037044688],"genre_scores_gemma":[0.9987712,0.000018811983,0.00028759358,0.00014627566,0.000029733066,0.00005911638,0.000038339178,0.000009420685,0.00063954055],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99772507,0.0003483817,0.0005435508,0.0008256851,0.00002304745,0.0005342538],"domain_scores_gemma":[0.99861825,0.00080246344,0.00020184203,0.00030266447,0.000027916778,0.000046874204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002561202,0.00023360195,0.00059056416,0.00014196194,0.0004167262,0.000052272306,0.00015809656,0.00032751833,0.00007695479],"category_scores_gemma":[0.00066117576,0.00017357968,0.00003557094,0.00015866893,0.00034068828,0.000101346144,0.0005501706,0.00027772138,0.000013950121],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013189137,0.000024596948,0.63265395,0.00002611906,0.000036122146,0.00001660616,0.00012220567,0.0000013677168,0.3649205,0.00034426572,0.00007818779,0.0016441778],"study_design_scores_gemma":[0.0009932853,0.0005933938,0.99432665,0.00008147269,0.000022491162,0.00038174065,0.00040076007,0.000017523087,0.0007859599,0.00022982748,0.0019202447,0.00024664943],"about_ca_topic_score_codex":0.00003374778,"about_ca_topic_score_gemma":0.00002407132,"teacher_disagreement_score":0.36413455,"about_ca_system_score_codex":0.000015513315,"about_ca_system_score_gemma":0.000016135658,"threshold_uncertainty_score":0.7078374},"labels":[],"label_agreement":null},{"id":"W2981766175","doi":"10.1016/j.biologicals.2019.10.008","title":"Quality changes to approved biotherapeutic product: Simulated case studies on reporting categories &amp; supporting data requirements","year":2019,"lang":"en","type":"review","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"World Health Organization","keywords":"Quality (philosophy); Product (mathematics); Business; Process management; Process (computing); Order (exchange); Operations management; Risk analysis (engineering); Computer science; Engineering; Finance","score_opus":0.7420894449380853,"score_gpt":0.5846845918852744,"score_spread":0.15740485305281082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981766175","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005952719,0.99347055,0.0000256936,0.0007160174,0.0017127316,0.0024607826,0.0006816925,0.00019435321,0.00014290753],"genre_scores_gemma":[0.00091068645,0.98991805,0.0013141843,0.0014694394,0.00027015616,0.00008930847,0.0016751159,0.00006393601,0.004289126],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99106985,0.0023568235,0.0033619374,0.002185539,0.000094904935,0.0009309708],"domain_scores_gemma":[0.9909974,0.0019533366,0.004229553,0.0025172657,0.0002236652,0.0000787813],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0087078,0.00087845256,0.0043286495,0.00020396398,0.00034229385,0.000054541986,0.0009768527,0.0011210685,0.00024278877],"category_scores_gemma":[0.017847743,0.00048842025,0.00037679417,0.0005380013,0.0004056999,0.000049481412,0.0013258035,0.00078332535,0.0004233769],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009183346,0.0002669553,0.000049171926,0.00706651,0.0027137804,0.00021059207,0.00012693454,6.160254e-7,0.002061877,0.00017083333,0.0030522982,0.9841886],"study_design_scores_gemma":[0.00018209829,0.00039637333,0.0000049501796,0.0017284062,0.00084868283,0.0004616077,0.00013298764,5.0967157e-7,0.00031987007,0.00007216753,0.9951104,0.0007419722],"about_ca_topic_score_codex":0.00004956696,"about_ca_topic_score_gemma":0.000052797175,"teacher_disagreement_score":0.9920581,"about_ca_system_score_codex":0.000121242556,"about_ca_system_score_gemma":0.0001337652,"threshold_uncertainty_score":0.99975675},"labels":[],"label_agreement":null},{"id":"W2999642303","doi":"10.1016/j.biologicals.2019.12.008","title":"WHO implementation workshop on guidelines on procedures and data requirements for changes to approved biotherapeutic products, Seoul, Republic of Korea, 25–26 June 2019","year":2020,"lang":"en","type":"article","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Ministry of Food and Drug Safety; World Health Organization","keywords":"Guideline; CLARITY; Product (mathematics); Business; Medicine; Medical education","score_opus":0.3059629528580957,"score_gpt":0.45261058716641406,"score_spread":0.14664763430831834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999642303","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14786828,0.013796714,0.0021665627,0.8242488,0.0011062085,0.0071105626,0.0031647645,0.00034262496,0.00019550424],"genre_scores_gemma":[0.62921363,0.011427842,0.093395896,0.24842241,0.0018678362,0.00077009405,0.0046128263,0.00019455339,0.010094902],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982858,0.00016815463,0.00042857937,0.0007674328,0.000046699188,0.0003033845],"domain_scores_gemma":[0.9989286,0.00023722231,0.00019050243,0.0004285836,0.00016602903,0.000049029644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007425033,0.0002092607,0.00041932028,0.00006674165,0.00008119338,0.000020308042,0.00038210838,0.000247633,0.000118235475],"category_scores_gemma":[0.0020872664,0.00012787254,0.000038834976,0.00022678576,0.00013739067,0.00004016487,0.00021844378,0.000101477264,0.000010528098],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009220583,0.00015097103,0.00027276628,0.0001095361,0.00021096451,3.3099715e-7,0.000082637205,3.987264e-7,0.5984354,0.0011600523,0.27884924,0.119805604],"study_design_scores_gemma":[0.0013160679,0.0034261658,0.0035193844,0.00012810087,0.00009816594,0.0000022522604,0.0002748923,0.000023948016,0.19147961,0.0002771951,0.79912925,0.00032494182],"about_ca_topic_score_codex":0.000008490864,"about_ca_topic_score_gemma":0.000017616208,"teacher_disagreement_score":0.57582635,"about_ca_system_score_codex":0.000010807412,"about_ca_system_score_gemma":0.000031129413,"threshold_uncertainty_score":0.5214491},"labels":[],"label_agreement":null},{"id":"W3008781252","doi":"10.1016/j.biologicals.2020.02.003","title":"Report of the 2019 NIST-FDA workshop on standards for next generation sequencing detection of viral adventitious agents in biologics and biomanufacturing","year":2020,"lang":"en","type":"article","venue":"Biologicals","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Food and drug administration; Biomanufacturing; Standardization; Biotechnology; Medicine; Computer science; Biology; Risk analysis (engineering)","score_opus":0.11266259333185935,"score_gpt":0.3514924686337048,"score_spread":0.23882987530184546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3008781252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977225,0.00059035106,0.0008663252,0.0001752759,0.000065071355,0.00042519206,0.00012501671,0.0000054912716,0.00002477216],"genre_scores_gemma":[0.99906516,0.00038784486,0.00012955019,0.00018826681,0.000097918215,0.000021951764,0.00008045376,0.0000070239794,0.000021835327],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903214,0.00013158086,0.00028945922,0.00028637255,0.000114090624,0.00014636271],"domain_scores_gemma":[0.9995087,0.00002798313,0.00016426289,0.00018380338,0.00008140848,0.000033842945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048669046,0.00010115555,0.00016134289,0.000028894714,0.000051551448,0.000009589018,0.00012779415,0.00016698717,0.0000064864466],"category_scores_gemma":[0.0004933166,0.00006588979,0.00008132269,0.00008238092,0.00010536482,0.0000033362842,0.000084478765,0.0000660004,2.551809e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066258304,0.00001938138,0.00076878147,0.000017207842,0.000019613917,0.0000019293905,0.000016746359,0.00029870175,0.99282837,0.0000051834063,0.00007060769,0.0052909157],"study_design_scores_gemma":[0.00038257585,0.0020131737,0.0022413929,0.000015811655,0.0000048172456,0.0000041259696,0.000025611416,0.00029136438,0.9941187,0.00007689502,0.00074681884,0.00007873164],"about_ca_topic_score_codex":0.000015401041,"about_ca_topic_score_gemma":0.00005656141,"teacher_disagreement_score":0.0052121845,"about_ca_system_score_codex":0.000033241937,"about_ca_system_score_gemma":0.00006223179,"threshold_uncertainty_score":0.26869076},"labels":[],"label_agreement":null},{"id":"W3013519416","doi":"10.1016/j.biologicals.2020.02.005","title":"The regulatory landscape of biosimilars: WHO efforts and progress made from 2009 to 2019","year":2020,"lang":"en","type":"review","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Ministry of Health and Welfare; World Health Organization","keywords":"Biosimilar; Business; Terminology; Competition (biology); Quality (philosophy); Risk analysis (engineering); Medicine","score_opus":0.04131380638215703,"score_gpt":0.33282749076361606,"score_spread":0.291513684381459,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3013519416","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012687096,0.9962001,0.0000068981626,0.0011534508,0.000367076,0.0008850013,0.0010344124,0.000047892463,0.00017831501],"genre_scores_gemma":[0.000050047445,0.99792475,0.0004961799,0.0005231854,0.00011749007,0.000059997332,0.00014177918,0.000021273914,0.00066529517],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971155,0.0008576767,0.0008252501,0.0007031767,0.00005262771,0.00044578195],"domain_scores_gemma":[0.9977479,0.0011687013,0.00041085674,0.000526088,0.000051657506,0.000094791416],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006566815,0.00047426453,0.002153053,0.00006654664,0.0001437433,0.000032992786,0.00061414036,0.0013241053,0.00027329504],"category_scores_gemma":[0.00034124154,0.0002161501,0.00042715215,0.00026852384,0.0007391213,0.000016415292,0.00047674752,0.00048864214,0.00010077188],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055282755,0.00003906662,0.00008354548,0.0003625111,0.00047302785,0.0000062496842,0.000009748245,5.924029e-9,0.00018824618,0.00028319636,0.050401267,0.9480978],"study_design_scores_gemma":[0.0001510618,0.0003641763,0.0006248161,0.0015277477,0.00044940584,0.000015423093,0.000008695412,2.2445934e-7,0.00023909539,0.00018539983,0.996131,0.00030297518],"about_ca_topic_score_codex":0.000004249853,"about_ca_topic_score_gemma":0.0000013933796,"teacher_disagreement_score":0.94779485,"about_ca_system_score_codex":0.000015133163,"about_ca_system_score_gemma":0.000066167464,"threshold_uncertainty_score":0.9999724},"labels":[],"label_agreement":null},{"id":"W3033731386","doi":"10.1016/j.biologicals.2020.04.004","title":"Third human challenge trial conference, Oxford, United Kingdom, February 6–7, 2020, a meeting report","year":2020,"lang":"en","type":"article","venue":"Biologicals","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Medical Research Council; Wellcome Trust","keywords":"Delegation; Standardization; Political science; Medicine; Public relations; Law","score_opus":0.22413496586953424,"score_gpt":0.3994632462707512,"score_spread":0.17532828040121695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033731386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93868995,0.000116189185,0.000083746185,0.00963348,0.000119962904,0.0008125121,0.000010287561,0.00025451274,0.050279357],"genre_scores_gemma":[0.9964839,0.00017204079,0.00017632898,0.0012701743,0.0010582263,0.00006480624,0.000195627,0.000012840202,0.0005660242],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982663,0.00017728287,0.00050485146,0.00044775638,0.0002424113,0.00036139053],"domain_scores_gemma":[0.9990366,0.00010380547,0.00013939987,0.000226655,0.00019098667,0.00030252608],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005963493,0.00017736349,0.00046847275,0.000092471426,0.00021344378,0.00004264412,0.00012472781,0.00025771325,0.0010111704],"category_scores_gemma":[0.0010192611,0.00011429209,0.00018379463,0.00047759735,0.00014225014,0.000041631964,0.00016092915,0.00044892658,0.00009126642],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06634352,0.0054561845,0.10511361,0.0008935663,0.0017779733,0.019129457,0.0012924377,0.000027270864,0.5859265,0.06423042,0.12219464,0.027614456],"study_design_scores_gemma":[0.063767806,0.026726546,0.05707044,0.00040743907,0.0002487817,0.00072315277,0.0006397974,0.0011394536,0.005732057,0.0019022946,0.84047556,0.0011666516],"about_ca_topic_score_codex":0.00031024593,"about_ca_topic_score_gemma":0.00001087577,"teacher_disagreement_score":0.7182809,"about_ca_system_score_codex":0.000030961353,"about_ca_system_score_gemma":0.000073206145,"threshold_uncertainty_score":0.99990207},"labels":[],"label_agreement":null},{"id":"W3080928896","doi":"10.1016/j.biologicals.2020.08.010","title":"SARS-CoV-2 and the safety margins of cell-based biological medicinal products","year":2020,"lang":"en","type":"article","venue":"Biologicals","topic":"Biomedical and Engineering Education","field":"Engineering","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Takeda Canada","keywords":"Biomanufacturing; Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Pandemic; Coronavirus disease 2019 (COVID-19); Industrial fermentation; 2019-20 coronavirus outbreak; Virus; Biology; Cell culture; Biotechnology; Medicine; Food science; Fermentation; Infectious disease (medical specialty); Outbreak; Disease","score_opus":0.03785850765158746,"score_gpt":0.22793506687077408,"score_spread":0.19007655921918662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3080928896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9743945,0.0026156574,0.007589311,0.013196321,0.0003084751,0.0003128118,0.00002501245,0.0002743133,0.0012836198],"genre_scores_gemma":[0.9978344,0.0002762697,0.0010042648,0.0006876193,0.00016125526,0.000012247673,0.000015431377,0.0000052863593,0.0000032202036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994061,0.000042596632,0.00019632462,0.00014422186,0.00007041771,0.00014035606],"domain_scores_gemma":[0.9996566,0.00015756105,0.000023602377,0.00009351789,0.000018935236,0.00004977385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022495782,0.00010357385,0.00021164605,0.000014874335,0.00002320191,0.0000048168026,0.00012372041,0.000107038155,0.00003152028],"category_scores_gemma":[0.00023748328,0.000049724596,0.000033050368,0.0001679378,0.0002820259,0.000011698173,0.000024823988,0.00012470564,0.000010439591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002104915,0.00006402876,0.00056944124,0.000499697,0.000035470344,0.0000030692192,0.00031804107,0.00035280787,0.9841828,0.0015949715,0.007420954,0.0047482406],"study_design_scores_gemma":[0.004650971,0.0009658054,0.063758336,0.00011512423,0.000070780676,0.0000118693815,0.00020591565,0.057877954,0.70242614,0.00088577205,0.16825452,0.0007768225],"about_ca_topic_score_codex":0.000004201337,"about_ca_topic_score_gemma":1.15755014e-7,"teacher_disagreement_score":0.28175667,"about_ca_system_score_codex":0.0000076127576,"about_ca_system_score_gemma":0.000009744451,"threshold_uncertainty_score":0.20277102},"labels":[],"label_agreement":null},{"id":"W3091934739","doi":"10.1016/j.biologicals.2020.07.010","title":"Animal testing for vaccines. Implementing replacement, reduction and refinement: challenges and priorities","year":2020,"lang":"en","type":"article","venue":"Biologicals","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Innovative Medicines Initiative; Humane Society International; European Federation of Pharmaceutical Industries and Associations; Bill and Melinda Gates Foundation","keywords":"Harmonization; Standardization; Alliance; Consistency (knowledge bases); Work (physics); Business; Medicine; Political science; Computer science; Engineering","score_opus":0.07222429780345258,"score_gpt":0.30801357871267665,"score_spread":0.23578928090922407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091934739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871236,0.011222251,0.000068652895,0.0008244856,0.000042893,0.00026111907,0.000023259756,0.00002768944,0.0004060602],"genre_scores_gemma":[0.99582297,0.0022351504,0.0010682046,0.00029176092,0.00044301242,0.00006670618,0.000028437373,0.000007866439,0.00003592326],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99924827,0.00003188637,0.0001578906,0.00035657984,0.000032401076,0.0001729796],"domain_scores_gemma":[0.99970067,0.000021636295,0.00007786122,0.00007651252,0.000047997768,0.00007532677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013353981,0.00010639334,0.00011020723,0.000010531654,0.00014514866,0.00002359538,0.000040356234,0.000072945986,0.0000104739265],"category_scores_gemma":[0.00031665716,0.00008347683,0.000029011107,0.000023448147,0.000032300904,0.000003864337,0.00015036037,0.000029025412,3.9440397e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024332962,0.00001590995,0.004751118,0.00009100927,0.000029746125,3.408914e-7,0.0000731841,8.551191e-7,0.97455,0.00028558803,0.0016760266,0.01828288],"study_design_scores_gemma":[0.0059090303,0.028009456,0.11649341,0.00015105522,0.00016329935,0.000099096134,0.0030639858,0.00043652699,0.38700077,0.0024955866,0.454652,0.0015257744],"about_ca_topic_score_codex":0.0000033400288,"about_ca_topic_score_gemma":9.73589e-7,"teacher_disagreement_score":0.58754927,"about_ca_system_score_codex":0.000002582319,"about_ca_system_score_gemma":0.000008760265,"threshold_uncertainty_score":0.34040862},"labels":[],"label_agreement":null},{"id":"W3093091675","doi":"10.1016/j.biologicals.2020.09.003","title":"Replacing the in vivo toxin challenge test with an in vitro assay for assessment of potency for diphtheria toxoid containing vaccines","year":2020,"lang":"en","type":"article","venue":"Biologicals","topic":"Diphtheria, Corynebacterium, and Tetanus","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Diphtheria toxin; Potency; Diphtheria; Toxoid; In vivo; Immunization; In vitro toxicology; Medicine; Virology; In vitro; Antibody; Toxin; Vaccination; Microbiology; Chemistry; Biology; Immunology; Biotechnology; Biochemistry","score_opus":0.03901331657394204,"score_gpt":0.30048690906763964,"score_spread":0.2614735924936976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3093091675","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99500114,0.00026411648,0.0021950447,0.0008149031,0.00004503123,0.0008821622,0.00012626292,0.000012790153,0.0006585231],"genre_scores_gemma":[0.995889,0.00006287856,0.0031168286,0.00038704026,0.00015468578,0.0002693283,0.00007485747,0.000016890084,0.00002850616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886185,0.00011560115,0.00031716505,0.0003994846,0.00005412702,0.00025178245],"domain_scores_gemma":[0.9993002,0.00019919599,0.00014987179,0.00023123632,0.0000672233,0.000052312524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058077165,0.00016604044,0.00030992113,0.000019317404,0.000039666447,0.000017052142,0.00023160197,0.00014375255,0.000015467367],"category_scores_gemma":[0.00045953624,0.00009761703,0.00007148328,0.000073033785,0.00004265084,0.000006219374,0.000056144254,0.00006386584,1.417761e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011000094,0.00015347968,0.005779663,0.000031309755,0.00002137847,0.0000022787367,0.00009891335,0.000016286782,0.98958755,0.0001150491,0.000016644226,0.0030774535],"study_design_scores_gemma":[0.0068612546,0.025683371,0.04227944,0.00010045868,0.00005271947,0.000012688942,0.002383027,0.0021353264,0.9000956,0.00067807775,0.018858891,0.00085913274],"about_ca_topic_score_codex":0.000016802323,"about_ca_topic_score_gemma":0.00007854716,"teacher_disagreement_score":0.08949192,"about_ca_system_score_codex":0.000012338057,"about_ca_system_score_gemma":0.00005221406,"threshold_uncertainty_score":0.3980707},"labels":[],"label_agreement":null},{"id":"W3160701503","doi":"10.1016/j.biologicals.2021.04.005","title":"IABS/CEPI platform technology webinar: Is it possible to reduce the vaccine development time?","year":2021,"lang":"en","type":"article","venue":"Biologicals","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Coalition for Epidemic Preparedness Innovations; World Health Organization; Bill and Melinda Gates Foundation","keywords":"Preparedness; Standardization; Coronavirus disease 2019 (COVID-19); Alliance; Pandemic; Joint venture; Emerging technologies; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Business; Technology development; Process (computing); Computer science; Risk analysis (engineering); Process management; Infectious disease (medical specialty); Engineering; Medicine; Disease; Political science; Management; Manufacturing engineering; Economics","score_opus":0.0818162448890902,"score_gpt":0.37796313876282894,"score_spread":0.2961468938737387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3160701503","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9460104,0.0010680099,0.000044483957,0.04114713,0.00007730068,0.00048781425,0.00000611077,0.00012741542,0.011031334],"genre_scores_gemma":[0.78095096,0.000054692387,0.0037505263,0.20808779,0.00026206224,0.00027503053,0.000017321536,0.00002715498,0.006574429],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983461,0.000038829792,0.0003413365,0.0004887088,0.0002571515,0.00052788755],"domain_scores_gemma":[0.99892294,0.0001665531,0.000049219558,0.0005651897,0.00023017511,0.00006592081],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004892311,0.00018762534,0.00037758856,0.00014641247,0.00018617639,0.000031038082,0.00035807284,0.00029950312,0.0008504537],"category_scores_gemma":[0.00078244833,0.00010126982,0.00008521178,0.0009142921,0.00007688266,0.00002764825,0.00045249224,0.0003111165,0.003207645],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003480557,0.00032602903,0.016520832,0.000035379857,0.00015025663,0.00023376991,0.00031962967,1.5121164e-7,0.8618081,0.00052743364,0.06165967,0.05807065],"study_design_scores_gemma":[0.0003991526,0.00025749483,0.005108867,0.000037139234,0.000009505033,0.00007089535,0.0002118602,0.0000063464227,0.46625373,0.00031003737,0.52723795,0.00009701678],"about_ca_topic_score_codex":0.000007737516,"about_ca_topic_score_gemma":0.000005569838,"teacher_disagreement_score":0.4655783,"about_ca_system_score_codex":0.00012263203,"about_ca_system_score_gemma":0.00042481153,"threshold_uncertainty_score":0.9975685},"labels":[],"label_agreement":null},{"id":"W3204361907","doi":"10.1016/j.biologicals.2021.09.002","title":"Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain","year":2021,"lang":"en","type":"article","venue":"Biologicals","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Medical Research Council; Wellcome Trust","keywords":"Documentation; Quality (philosophy); Good manufacturing practice; Process (computing); Product (mathematics); Risk analysis (engineering); Control (management); Process management; Computer science; Quality by Design; New product development; Manufacturing process; Manufacturing engineering; Business; Operations management; Engineering; Marketing","score_opus":0.2536574262357846,"score_gpt":0.4428838146075007,"score_spread":0.18922638837171613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204361907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9322566,0.0026383614,0.0062940507,0.05456712,0.000101448124,0.0038755948,0.000037133133,0.00008414114,0.00014555539],"genre_scores_gemma":[0.98275274,0.0011577214,0.011693279,0.0021327161,0.00025881603,0.0011571236,0.000027393306,0.000009549469,0.0008106828],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99829924,0.00047987854,0.00027042007,0.00047173304,0.000087675275,0.00039105272],"domain_scores_gemma":[0.9989461,0.0002482564,0.00006345249,0.00015998278,0.00042092256,0.00016128982],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0013907546,0.00014857347,0.0007060921,0.000052227402,0.000115172275,0.000016203134,0.000043573513,0.00010344117,0.000017160008],"category_scores_gemma":[0.018875977,0.00009069094,0.00006695029,0.00010720733,0.00010104601,0.000023137232,0.00006348799,0.00010966168,0.0000069254916],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007615853,0.00084529695,0.011504722,0.00053828553,0.0007119766,0.00019828623,0.0002773554,0.000008846542,0.90244657,0.002241152,0.027367808,0.04624382],"study_design_scores_gemma":[0.07363325,0.17652635,0.5132001,0.0033721908,0.00031517836,0.00056071987,0.0017075104,0.0002873321,0.067248404,0.019786524,0.14158776,0.0017746795],"about_ca_topic_score_codex":0.0000020572322,"about_ca_topic_score_gemma":0.000016647016,"teacher_disagreement_score":0.83519816,"about_ca_system_score_codex":0.00005501618,"about_ca_system_score_gemma":0.00005689809,"threshold_uncertainty_score":0.98938847},"labels":[],"label_agreement":null},{"id":"W4224288018","doi":"10.1016/j.biologicals.2022.03.001","title":"WHO informal consultation on revision of guidelines on evaluation of similar biotherapeutic products, virtual meeting, 30 June – 2 July 2021","year":2022,"lang":"en","type":"article","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Ministry of Health and Welfare; World Health Organization","keywords":"CLARITY; Biosimilar; Flexibility (engineering); Standardization; Medicine; Engineering ethics; Risk analysis (engineering); Management science; Business; Medical education; Engineering management; Political science; Engineering; Law; Management","score_opus":0.1113743065632104,"score_gpt":0.378385527609463,"score_spread":0.2670112210462526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224288018","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9792576,0.009270835,0.0001076505,0.004124962,0.0013251671,0.0015365332,0.0004434108,0.000050879058,0.0038829567],"genre_scores_gemma":[0.9948007,0.0006749075,0.0011537516,0.0018308456,0.00007187572,0.000027335615,0.00016970912,0.000010795532,0.0012600641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971786,0.0013203092,0.0007722111,0.00033711805,0.00018327241,0.00020847014],"domain_scores_gemma":[0.9981054,0.00050456397,0.00047445725,0.00028377635,0.00061545294,0.000016365351],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004077255,0.0001750627,0.00044251356,0.00012254946,0.00014390824,0.0000045565716,0.00021237516,0.00022829167,0.0025481067],"category_scores_gemma":[0.0035870485,0.000114453265,0.00011069423,0.00032645828,0.00025371654,0.00002645929,0.000105714826,0.0002399272,0.00003753913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014390727,0.0006444837,0.00032247626,0.00004654291,0.00024376929,8.0422444e-7,0.00018674626,0.0009876632,0.7396649,0.0031265623,0.021714386,0.23162256],"study_design_scores_gemma":[0.0022788416,0.005963675,0.0029369507,0.00016981331,0.00021240958,0.000005562741,0.00033526623,0.0005520739,0.5207384,0.0003157232,0.4661825,0.00030875634],"about_ca_topic_score_codex":0.000005483879,"about_ca_topic_score_gemma":3.7753063e-7,"teacher_disagreement_score":0.4444681,"about_ca_system_score_codex":0.00003317699,"about_ca_system_score_gemma":0.00007530706,"threshold_uncertainty_score":0.9983637},"labels":[],"label_agreement":null},{"id":"W4285097669","doi":"10.1016/j.biologicals.2022.06.003","title":"Accelerating Global Deletion of the Abnormal Toxicity Test for vaccines and biologicals. Planning common next steps. A workshop Report","year":2022,"lang":"en","type":"article","venue":"Biologicals","topic":"Animal testing and alternatives","field":"Veterinary","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"World Health Organization; Bill and Melinda Gates Foundation","keywords":"Standardization; Test (biology); Alliance; Business; Medicine; Political science; Biology","score_opus":0.31995780295158077,"score_gpt":0.4275266073901094,"score_spread":0.10756880443852862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285097669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977779,0.0005227578,0.00019531354,0.00025365487,0.00010111344,0.00035217265,0.000115804236,0.0000874002,0.0005938832],"genre_scores_gemma":[0.99804264,0.000008840016,0.0014483533,0.00021252519,0.000114932845,0.00009190961,0.000025913565,0.0000053416607,0.000049541508],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987239,0.00021951106,0.0004073265,0.00032335048,0.00010056421,0.00022531606],"domain_scores_gemma":[0.99825406,0.0011116668,0.0003841572,0.00016603692,0.000047892638,0.000036189693],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068370346,0.00014570287,0.00027645964,0.000014890377,0.0004927368,0.000033241387,0.00026468473,0.00007388596,0.00006096902],"category_scores_gemma":[0.0016544787,0.00008383588,0.00009237038,0.00015453287,0.00009588726,0.000054332882,0.0005467197,0.00015966097,5.1401645e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044749418,0.00020137767,0.93377805,0.000025685938,0.000029706978,0.000075457094,0.00012162246,0.00012259545,0.05695652,0.0006334493,0.000358217,0.0072498345],"study_design_scores_gemma":[0.0005224401,0.003839264,0.98571324,0.00007641995,0.00002471526,0.0009592165,0.0014202447,0.0023600163,0.00076432724,0.002322414,0.001699303,0.00029839255],"about_ca_topic_score_codex":0.000028435208,"about_ca_topic_score_gemma":0.0000015800632,"teacher_disagreement_score":0.05619219,"about_ca_system_score_codex":0.000033083943,"about_ca_system_score_gemma":0.000012933556,"threshold_uncertainty_score":0.37897828},"labels":[],"label_agreement":null},{"id":"W4308327388","doi":"10.1016/j.biologicals.2022.11.001","title":"Corrigendum to “Replacing the in vivo toxin challenge test with an in vitro assay for assessment of potency for diphtheria toxoid containing vaccines” [Biologicals 68 (2020) 19–25]","year":2022,"lang":"en","type":"erratum","venue":"Biologicals","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Potency; Diphtheria toxin; Toxoid; Diphtheria; In vivo; In vitro; In vitro toxicology; Toxin; Microbiology; Pharmacology; Chemistry; Medicine; Virology; Biology; Biotechnology; Vaccination; Tetanus; Biochemistry","score_opus":0.03930016330654674,"score_gpt":0.2994283051198831,"score_spread":0.2601281418133364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308327388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.49365658,0.08838259,0.03246871,0.018393608,0.15970963,0.10739102,0.061108183,0.0019703915,0.036919296],"genre_scores_gemma":[0.9323916,0.0017192232,0.0068775737,0.0021832082,0.0006717809,0.010706643,0.00511171,0.00019824556,0.040140018],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9944578,0.0012233407,0.0014707103,0.0014707916,0.0001139685,0.001263413],"domain_scores_gemma":[0.9958816,0.001970348,0.0009304054,0.00095983234,0.00017558497,0.00008219279],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0037899406,0.0008459743,0.0020532385,0.00029287682,0.00044087946,0.00004274563,0.0014120506,0.0015501851,0.0021886812],"category_scores_gemma":[0.0018376643,0.00049954,0.0003554095,0.0004219892,0.00017376141,0.00008425792,0.00048676564,0.0014255673,0.000007784295],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034823534,0.0014225956,0.0007346077,0.00014716196,0.0002727445,0.00003018085,0.0004944271,0.000027763082,0.94890213,0.0020247912,0.0375375,0.004923768],"study_design_scores_gemma":[0.0062145875,0.03321877,0.007669728,0.0003775371,0.00015734055,0.00007341363,0.0047441563,0.00013127095,0.01667634,0.0017089319,0.92723763,0.0017902671],"about_ca_topic_score_codex":0.00029805588,"about_ca_topic_score_gemma":0.0003737437,"teacher_disagreement_score":0.93222576,"about_ca_system_score_codex":0.00034072762,"about_ca_system_score_gemma":0.00040940125,"threshold_uncertainty_score":0.999746},"labels":[],"label_agreement":null},{"id":"W4368348217","doi":"10.1016/j.biologicals.2023.101683","title":"Development of a droplet digital PCR for pertussis toxin locus copy number determination in a genetically-modified Bordetella pertussis strain","year":2023,"lang":"en","type":"article","venue":"Biologicals","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi Pasteur","keywords":"Locus (genetics); Bordetella pertussis; Pertussis toxin; Biology; Gene; Strain (injury); Digital polymerase chain reaction; Genetics; Polymerase chain reaction; Bacteria; Receptor; G protein","score_opus":0.04153103462502097,"score_gpt":0.30193191874022673,"score_spread":0.2604008841152058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4368348217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99769455,0.00006180537,0.00078928075,0.00017180933,0.00022356745,0.00038762498,0.00022206597,0.00007514254,0.00037416857],"genre_scores_gemma":[0.9977681,0.000051807543,0.0009994264,0.00003165589,0.00002762363,0.00016887981,0.00041555837,0.000010446456,0.0005265273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987891,0.00007934693,0.00048727248,0.00029861953,0.000016936492,0.00032878137],"domain_scores_gemma":[0.9993606,0.00031395,0.0001026017,0.00012728131,0.00007247174,0.000023046414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002800307,0.0001629239,0.0003350969,0.00011054921,0.00009949514,0.000022907761,0.00013177835,0.00033435787,0.00048149808],"category_scores_gemma":[0.0002754472,0.000115573326,0.00010089327,0.00023931041,0.00008986889,0.000045179055,0.00007940292,0.00007790183,0.0001608573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017849985,0.00019540152,0.0053312825,0.000021418544,0.000046164987,9.89327e-7,0.00024987216,0.0000018208359,0.8470121,0.00029515644,0.0002848536,0.14638244],"study_design_scores_gemma":[0.0069938344,0.001407567,0.27796838,0.00017647284,0.00007225044,0.00006722788,0.0011007042,0.00031882088,0.4783058,0.0020759662,0.23012422,0.0013887611],"about_ca_topic_score_codex":0.0000108701915,"about_ca_topic_score_gemma":0.0000312615,"teacher_disagreement_score":0.36870632,"about_ca_system_score_codex":0.00003291454,"about_ca_system_score_gemma":0.00005211476,"threshold_uncertainty_score":0.5272066},"labels":[],"label_agreement":null},{"id":"W4385064422","doi":"10.1016/j.biologicals.2023.101696","title":"Report of the third conference on next-generation sequencing for adventitious virus detection in biologics for humans and animals","year":2023,"lang":"en","type":"article","venue":"Biologicals","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"World Health Organization","keywords":"Standardization; Food and drug administration; Workflow; Government (linguistics); DNA sequencing; Biotechnology; Alliance; Medicine; Business; Biology; Risk analysis (engineering); Political science; Computer science; Gene","score_opus":0.26073826987097715,"score_gpt":0.3172537208268608,"score_spread":0.05651545095588367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385064422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99838835,0.00007020837,0.000051066163,0.0003277469,0.00012285991,0.00069638604,0.000112530695,0.000060106264,0.00017077038],"genre_scores_gemma":[0.99917674,0.00021211623,0.00007255797,0.00008200791,0.000119030075,0.00023971686,0.00003455839,6.842699e-7,0.000062581035],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991613,0.00007174782,0.0002705681,0.00026903278,0.00005450426,0.00017287249],"domain_scores_gemma":[0.9993386,0.00035014565,0.00015603242,0.000045252295,0.00009378429,0.000016177173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054094486,0.000098203884,0.00017628813,0.000017288268,0.00031359063,0.000021589045,0.00009026928,0.00012394048,0.0000102931535],"category_scores_gemma":[0.0006702379,0.000032472122,0.00007810737,0.00024009155,0.000112657515,0.000032642132,0.000058210946,0.00005330545,0.000002546419],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002946927,0.000017235387,0.0043179197,0.0000057916286,0.0000058803325,6.400634e-7,0.000019984718,0.000009386326,0.9887369,0.002005177,0.00008987196,0.0047617014],"study_design_scores_gemma":[0.00042457748,0.004597081,0.608794,0.00006823771,0.00003230167,0.000018536586,0.0011601243,0.0018462604,0.3486746,0.026759285,0.007197706,0.00042728786],"about_ca_topic_score_codex":0.00014009564,"about_ca_topic_score_gemma":0.002035825,"teacher_disagreement_score":0.64006233,"about_ca_system_score_codex":0.000031943022,"about_ca_system_score_gemma":0.00000564315,"threshold_uncertainty_score":0.24119174},"labels":[],"label_agreement":null},{"id":"W4385664125","doi":"10.1016/j.biologicals.2023.101698","title":"Stability of lyophilized Meningococcal A conjugate vaccine, (MenAfriVac™) at elevated temperatures to support controlled temperature chain (CTC) claim","year":2023,"lang":"en","type":"article","venue":"Biologicals","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health Canada","keywords":"Vial; Conjugate; Meningococcal vaccine; Conjugate vaccine; Potency; Cold chain; Neisseria meningitidis; Consistency (knowledge bases); Product (mathematics); Medicine; Chemistry; Chromatography; Immunization; Mathematics; Antigen; Food science; Immunology; Biology","score_opus":0.026817384635690375,"score_gpt":0.2790891226149432,"score_spread":0.2522717379792528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385664125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953789,0.00024528767,0.0000018194888,0.0010546892,0.00087795197,0.0013996878,0.00044290684,0.00039128214,0.00020743604],"genre_scores_gemma":[0.9965426,0.0001073812,0.00002949435,0.00027663793,0.000096117605,0.00029131008,0.00076498196,0.0000199522,0.0018715416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972251,0.000655595,0.00084695546,0.0006237024,0.0000297269,0.0006188876],"domain_scores_gemma":[0.99844074,0.00051763235,0.00022474823,0.00048923696,0.0002453602,0.00008228177],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010022004,0.00037544643,0.0012030444,0.00019198722,0.0003045616,0.0000270322,0.0003058609,0.00065615005,0.00501678],"category_scores_gemma":[0.0008912202,0.00023481133,0.00029440993,0.00066040014,0.00010952497,0.000051881805,0.0003031437,0.0003007789,0.00068878377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004192688,0.00016802485,0.007705715,0.00001806104,0.00024435212,0.0000033519952,0.00012404082,0.000002579805,0.97388756,0.00044019558,0.013139647,0.00007378431],"study_design_scores_gemma":[0.0133665595,0.002493784,0.054591175,0.000037681355,0.00008377458,0.00005018996,0.00017614492,0.000003853491,0.87082255,0.00020091332,0.057638127,0.0005352269],"about_ca_topic_score_codex":0.000050676037,"about_ca_topic_score_gemma":0.000040684587,"teacher_disagreement_score":0.10306499,"about_ca_system_score_codex":0.00005535329,"about_ca_system_score_gemma":0.00005711596,"threshold_uncertainty_score":0.99589276},"labels":[],"label_agreement":null},{"id":"W4387387969","doi":"10.1016/j.biologicals.2023.101714","title":"Emergence of SARS-CoV-2 variant of interest B.1.525 (Eta) in Bangladesh","year":2023,"lang":"en","type":"article","venue":"Biologicals","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sciencetech (Canada)","funders":"","keywords":"Mutation; Biology; Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Gene; Genetics; Coronavirus; Genome; Spike Protein; Lineage (genetic); Strain (injury); Coronavirus disease 2019 (COVID-19); Medicine","score_opus":0.24020871811208122,"score_gpt":0.4197195344675895,"score_spread":0.17951081635550825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387387969","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99590325,0.00030833136,0.000044246135,0.00036636958,0.00011174729,0.0002966691,0.00002253186,0.00005375197,0.0028931194],"genre_scores_gemma":[0.99699616,0.000055550034,0.00012035533,0.0026921323,0.00005425666,0.000029840878,0.00000725219,0.000008923654,0.00003552785],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859583,0.0001201158,0.0004858804,0.0002960166,0.0001769948,0.00032516188],"domain_scores_gemma":[0.9991956,0.00025465302,0.00009767892,0.00032594043,0.00010503917,0.000021095208],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074252905,0.00012496309,0.00046708653,0.00025797664,0.000015468257,0.000003729263,0.0002526674,0.00018046028,0.000080397105],"category_scores_gemma":[0.0009775456,0.000083778745,0.00012704312,0.000935274,0.00020115494,0.000027092558,0.0001767449,0.00018496183,0.00014820162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002130612,0.00017694745,0.06694274,0.0001062904,0.00003095939,0.0001405984,0.00010106976,1.5571085e-7,0.92678946,0.0009587867,0.0019596382,0.0025802837],"study_design_scores_gemma":[0.00078833837,0.0007726611,0.09166153,0.00016375734,0.000013785808,0.000013728189,0.00022145957,0.0002016733,0.8905939,0.0012192612,0.014230758,0.00011913931],"about_ca_topic_score_codex":0.00020697423,"about_ca_topic_score_gemma":0.000054148255,"teacher_disagreement_score":0.03619556,"about_ca_system_score_codex":0.000016238844,"about_ca_system_score_gemma":0.0000794748,"threshold_uncertainty_score":0.34163982},"labels":[],"label_agreement":null},{"id":"W4388741210","doi":"10.1016/j.biologicals.2023.101723","title":"Enabling the evaluation of COVID-19 vaccines with correlates of protection","year":2023,"lang":"en","type":"article","venue":"Biologicals","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health Canada; U.S. Food and Drug Administration; University of Oxford; University of Washington; Imperial College London; Dartmouth College; California Institute of Technology; Emory University; Yale University; Coalition for Epidemic Preparedness Innovations; University of Pennsylvania; National Institutes of Health; London School of Hygiene and Tropical Medicine","keywords":"Coronavirus disease 2019 (COVID-19); Pandemic; Standardization; Vaccination; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Medicine; Alliance; Vaccine efficacy; Virology; Immunology; Computer science; Political science; Outbreak; Infectious disease (medical specialty); Disease","score_opus":0.22366448596766772,"score_gpt":0.4312918725802356,"score_spread":0.20762738661256788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388741210","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997071,0.00041147173,0.00019951507,0.0009160204,0.000033209843,0.0009795909,0.0000031768084,0.000058517693,0.0003274921],"genre_scores_gemma":[0.99829656,0.000017012184,0.000019547033,0.0014486223,0.000049306793,0.00014156122,0.000004275691,0.0000046950427,0.000018403593],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989543,0.00020078915,0.00019494945,0.00015575076,0.000364233,0.00012999862],"domain_scores_gemma":[0.9990208,0.0003499369,0.000105763465,0.00018773977,0.0003176316,0.000018123585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022121363,0.00006689575,0.00018105477,0.000107012354,0.00005619773,0.0000044603375,0.00008427713,0.00008724609,0.000037315935],"category_scores_gemma":[0.0032696605,0.000029594114,0.000047283374,0.0006415091,0.00009715768,0.000018952336,0.0000366582,0.00009825798,0.000020291669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001299913,0.00014659279,0.27404603,0.00027537852,0.00012516056,0.000007250611,0.00046959164,0.00015369186,0.6979977,0.0003039972,0.00027118844,0.024903512],"study_design_scores_gemma":[0.005577381,0.004469884,0.4052213,0.00025925835,0.00033619953,0.000058038502,0.0026596216,0.015537679,0.5337914,0.006197712,0.025642103,0.000249364],"about_ca_topic_score_codex":0.00010719033,"about_ca_topic_score_gemma":0.000009032421,"teacher_disagreement_score":0.16420624,"about_ca_system_score_codex":0.000039951185,"about_ca_system_score_gemma":0.00022795048,"threshold_uncertainty_score":0.39143252},"labels":[],"label_agreement":null},{"id":"W4391781144","doi":"10.1016/j.biologicals.2024.101747","title":"Fourth Controlled Human Infection Model (CHIM) meeting – CHIMs in endemic countries, May 22–23, 2023","year":2024,"lang":"en","type":"article","venue":"Biologicals","topic":"Vaccine Coverage and Hesitancy","field":"Social Sciences","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Bill and Melinda Gates Foundation; European Commission; Medical Research Council; European Federation of Pharmaceutical Industries and Associations; Uganda National Council for Science and Technology; Wellcome Trust","keywords":"Incentive; Community engagement; Political science; Public relations; Economics","score_opus":0.04671254954478212,"score_gpt":0.3447865623980175,"score_spread":0.2980740128532354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391781144","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93494725,0.0026979614,0.0003138437,0.0015413476,0.00037260412,0.0007071583,0.0000143815205,0.00027534788,0.05913012],"genre_scores_gemma":[0.9930513,0.0018141477,0.00006237106,0.0003209564,0.00047746857,0.000089290246,0.00001598217,0.000008014852,0.0041604787],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984957,0.00028782993,0.0003474293,0.00032419604,0.00016882595,0.00037600702],"domain_scores_gemma":[0.9993092,0.00040655723,0.000070188646,0.00010416434,0.000041909505,0.00006802329],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015591811,0.00013682977,0.0003334578,0.000111105204,0.0003457807,0.00013466163,0.00014954752,0.00024498036,0.0004795017],"category_scores_gemma":[0.00058661745,0.00009888617,0.00012644126,0.00028866422,0.000035199933,0.00015076406,0.000043893026,0.00017042804,0.0001659651],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034384028,0.0002853573,0.47635606,0.00010478488,0.00018738402,0.00013704065,0.005465611,0.00205619,0.014241278,0.4647558,0.030082151,0.0059845126],"study_design_scores_gemma":[0.012146377,0.0011494886,0.16104935,0.0016118037,0.00027082805,0.000012901116,0.0019127841,0.038677163,0.0006496717,0.3167223,0.46289477,0.0029025406],"about_ca_topic_score_codex":0.0012429924,"about_ca_topic_score_gemma":0.0035667997,"teacher_disagreement_score":0.43281263,"about_ca_system_score_codex":0.00013336983,"about_ca_system_score_gemma":0.000117553056,"threshold_uncertainty_score":0.5250207},"labels":[],"label_agreement":null},{"id":"W4392678954","doi":"10.1016/j.biologicals.2024.101756","title":"Maintaining the quality of vaccines through the use of standards: Current challenges and future opportunities","year":2024,"lang":"en","type":"article","venue":"Biologicals","topic":"Diphtheria, Corynebacterium, and Tetanus","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"World Health Organization","keywords":"Harmonization; Quality (philosophy); Business; Standardization; International standard; Human use; Best practice; Biotechnology; Good laboratory practice; Diversity (politics); Risk analysis (engineering); Engineering management; Quality assurance; Marketing; Engineering; Political science; Biology","score_opus":0.2280737115738715,"score_gpt":0.3680801841842667,"score_spread":0.1400064726103952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392678954","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84962654,0.14608803,0.00009524966,0.002491479,0.00032990295,0.00016620931,0.00027402962,0.000014632998,0.0009139275],"genre_scores_gemma":[0.9030251,0.09636457,0.000055558958,0.00009917795,0.0003577706,0.000012765269,0.000024029918,0.0000061334986,0.000054910157],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.999098,0.00024387681,0.00024779685,0.00019286998,0.000097754484,0.00011971802],"domain_scores_gemma":[0.9993787,0.00014888786,0.00009476583,0.00026128307,0.000096645286,0.000019739206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056581176,0.000116305215,0.00018388861,0.000009080779,0.000045307745,0.00002428942,0.00014904464,0.000090676374,0.00003150205],"category_scores_gemma":[0.00014029599,0.000050057504,0.00008759822,0.000028404795,0.00022844992,0.000005595319,0.00012478261,0.00006986068,2.3719748e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043048858,0.00013142999,0.00053252454,0.0004631095,0.00042968077,0.000005464185,0.0023230764,0.000004606109,0.13316746,0.11321898,0.0028615627,0.74643165],"study_design_scores_gemma":[0.00010841711,0.00029910012,0.0077100745,0.000044151348,0.00002399875,0.000006436076,0.0025288311,0.0000026651558,0.0059254873,0.0016058752,0.98164046,0.000104508355],"about_ca_topic_score_codex":0.000008896553,"about_ca_topic_score_gemma":0.000010120571,"teacher_disagreement_score":0.9787789,"about_ca_system_score_codex":0.0000034929553,"about_ca_system_score_gemma":0.000042757678,"threshold_uncertainty_score":0.20412858},"labels":[],"label_agreement":null},{"id":"W4403146384","doi":"10.1016/j.biologicals.2024.101794","title":"Assessment of the risks associated with the use of in vivo versus in vitro potency tests for vaccines","year":2024,"lang":"en","type":"editorial","venue":"Biologicals","topic":"Respiratory viral infections research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health Canada","keywords":"Potency; In vivo; In vitro; Pharmacology; Chemistry; Medicine; Biology; Biotechnology; Biochemistry","score_opus":0.20292589142107495,"score_gpt":0.4622782736684853,"score_spread":0.2593523822474103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403146384","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83971834,0.00063208095,0.000012794342,0.00071329897,0.15296355,0.0041579804,0.0012160139,0.000044346103,0.00054162],"genre_scores_gemma":[0.93322253,0.0002824789,0.00020159753,0.000060164068,0.06382569,0.00083817565,0.0001422497,0.000054165987,0.0013729185],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.997954,0.00046652614,0.000507359,0.0003277214,0.00047740733,0.0002669456],"domain_scores_gemma":[0.99265844,0.006177586,0.00028209636,0.00043183914,0.00041757373,0.000032451517],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0012061713,0.00020808737,0.00067573553,0.00019827121,0.000036289377,0.000020952273,0.00027489234,0.00067306834,0.00003377368],"category_scores_gemma":[0.012074869,0.000082482475,0.00017497168,0.00076531444,0.00017436987,0.000030613304,0.00014878712,0.0009287333,9.812346e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036203673,0.0010768656,0.040730055,0.00047311062,0.00059037685,0.000032559627,0.000042281732,0.00014261215,0.07712976,0.00007273326,0.8746595,0.0014297795],"study_design_scores_gemma":[0.008266527,0.008085827,0.3278565,0.0017898162,0.00040845454,0.0000012499612,0.000083417995,0.00032808477,0.0076910527,0.00014566477,0.6449324,0.0004110146],"about_ca_topic_score_codex":0.00042878877,"about_ca_topic_score_gemma":0.0004897496,"teacher_disagreement_score":0.28712648,"about_ca_system_score_codex":0.00029071898,"about_ca_system_score_gemma":0.0005567085,"threshold_uncertainty_score":0.9962468},"labels":[],"label_agreement":null},{"id":"W4403385257","doi":"10.1016/j.biologicals.2024.101796","title":"A vision for patient-centric specifications for biologicals","year":2024,"lang":"en","type":"editorial","venue":"Biologicals","topic":"Cell Image Analysis Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Medical physics; Computer science; Medicine","score_opus":0.022935851109291146,"score_gpt":0.32655556894667487,"score_spread":0.30361971783738373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403385257","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0061964993,0.09275127,0.089753896,0.0015787478,0.7686715,0.01779459,0.0167957,0.0013618664,0.005095901],"genre_scores_gemma":[0.007677587,0.010988493,0.02086972,0.00041461745,0.8952375,0.0051086596,0.051376574,0.00017347714,0.008153391],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971622,0.0001169014,0.0006743622,0.0013800325,0.00018044324,0.00048603056],"domain_scores_gemma":[0.9975656,0.00070209766,0.00032558665,0.00076049264,0.0005391059,0.00010708933],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00056983624,0.00046590238,0.0006236335,0.00014718359,0.00013716196,0.000119045915,0.00058191083,0.0020443574,0.000043924225],"category_scores_gemma":[0.004209902,0.00032286384,0.00085032167,0.00019679272,0.00015902563,0.0000029129071,0.00031775996,0.00024226661,0.000050031114],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011879445,0.00013349665,0.0000028242462,0.00006715029,0.0001262981,0.0000011859721,0.0000025933239,3.2641296e-7,0.13125825,0.00006920502,0.86171585,0.006504037],"study_design_scores_gemma":[0.00024216132,0.0020206075,0.0000032769499,0.000041469302,0.00016621385,8.3867246e-7,0.000009348576,0.000016799284,0.035970524,0.0015774508,0.9595083,0.0004429804],"about_ca_topic_score_codex":0.0000034423133,"about_ca_topic_score_gemma":0.000003903449,"teacher_disagreement_score":0.12656595,"about_ca_system_score_codex":0.00005056473,"about_ca_system_score_gemma":0.00011162279,"threshold_uncertainty_score":0.99992234},"labels":[],"label_agreement":null},{"id":"W4404659718","doi":"10.1016/j.biologicals.2024.101808","title":"The impact of LPS mutants on endotoxin masking in different detection systems","year":2024,"lang":"en","type":"article","venue":"Biologicals","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Advanced Micro Devices (Canada)","funders":"","keywords":"Masking (illustration); Mutant; Chemistry; Microbiology; Biology; Computational biology; Biochemistry; Gene","score_opus":0.01849848729144004,"score_gpt":0.2881980950023824,"score_spread":0.26969960771094237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404659718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924011,0.0058744648,0.00008601167,0.00003074248,0.0004702595,0.00023866318,0.000007526637,0.00007102454,0.0008201817],"genre_scores_gemma":[0.99895465,0.00029653465,3.757689e-7,0.0000027231695,0.000024411922,0.00003508213,0.00000951299,0.0000068664563,0.0006698662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990447,0.0003871147,0.00024341825,0.00013042847,0.000016854545,0.00017746522],"domain_scores_gemma":[0.99931926,0.00047591754,0.000060445127,0.00012941855,0.000009609611,0.000005342015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034979108,0.0000998766,0.00016707068,0.00009674647,0.000056606375,0.000017302793,0.00009184426,0.00017104155,0.000046761972],"category_scores_gemma":[0.0001313701,0.000043187527,0.00009380288,0.00010330875,0.000067211266,0.000020374124,0.000023549042,0.00013659126,0.00010147374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023293438,0.000026605014,0.00049302564,0.000008618933,0.00006386666,0.0000033291456,0.000045741617,0.000026539876,0.98466045,0.00067094783,0.00015851184,0.013609414],"study_design_scores_gemma":[0.00042685727,0.0010228277,0.07772353,0.00024600685,0.000008975047,0.000041741332,0.00014540553,0.00030423643,0.9142007,0.00022850292,0.0055172336,0.00013397474],"about_ca_topic_score_codex":0.00013920279,"about_ca_topic_score_gemma":0.00000650138,"teacher_disagreement_score":0.077230506,"about_ca_system_score_codex":0.000055348755,"about_ca_system_score_gemma":0.00001156641,"threshold_uncertainty_score":0.17611362},"labels":[],"label_agreement":null},{"id":"W4405618609","doi":"10.1016/j.biologicals.2024.101778","title":"Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Summary of NC3Rs final report to WHO Expert Committee for Biological Standardisation","year":2024,"lang":"en","type":"article","venue":"Biologicals","topic":"Respiratory viral infections research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"National Centre for the Replacement Refinement and Reduction of Animals in Research; National Centre for the Replacement, Refinement and Reduction of Animals in Research; Bill and Melinda Gates Foundation","keywords":"Biochemical engineering; Computer science; Engineering","score_opus":0.620108000662358,"score_gpt":0.5044749024143836,"score_spread":0.11563309824797441,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405618609","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.948046,0.0049903593,0.03690265,0.0053512254,0.00014778855,0.0036412473,0.00020509025,0.00011461997,0.000600991],"genre_scores_gemma":[0.96425873,0.0002447105,0.032834306,0.00058185705,0.0003766971,0.0013579294,0.000093560135,0.000021124202,0.00023107354],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972631,0.00027265958,0.0013277443,0.0005554183,0.00021730401,0.0003638067],"domain_scores_gemma":[0.99343514,0.005118766,0.00020477585,0.00037953438,0.00076755235,0.000094225725],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0044652694,0.00022858684,0.00073279935,0.00020799431,0.00011824199,0.00003218725,0.00023561064,0.00029696862,0.0000321436],"category_scores_gemma":[0.0436278,0.000108997294,0.0002665788,0.00073505135,0.0003684871,0.000057065303,0.00014478083,0.0002628742,0.0000014989353],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002873095,0.00061360886,0.189283,0.0008904311,0.0003113432,0.00007826142,0.00046630477,0.00072179234,0.27586257,0.006018638,0.036991354,0.4858896],"study_design_scores_gemma":[0.0060422495,0.039770525,0.2180072,0.008609199,0.00030103774,0.00038894147,0.010998518,0.098966084,0.16204725,0.0136756655,0.4391993,0.0019940338],"about_ca_topic_score_codex":0.000108352775,"about_ca_topic_score_gemma":0.0000124223925,"teacher_disagreement_score":0.48389557,"about_ca_system_score_codex":0.00010667011,"about_ca_system_score_gemma":0.00017284555,"threshold_uncertainty_score":0.9644281},"labels":[],"label_agreement":null},{"id":"W4405651690","doi":"10.1016/j.biologicals.2024.101777","title":"Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Reports from a series of NC3Rs stakeholder workshops","year":2024,"lang":"en","type":"article","venue":"Biologicals","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Bill and Melinda Gates Foundation","keywords":"Stakeholder; Series (stratigraphy); Computer science; Information retrieval; Biology; Public relations; Political science","score_opus":0.6754634032037169,"score_gpt":0.4560452493986532,"score_spread":0.2194181538050637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405651690","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9272739,0.052241072,0.0010315925,0.0161768,0.0002375999,0.0010845088,0.00009653594,0.00009103793,0.0017669053],"genre_scores_gemma":[0.98130995,0.0016577756,0.016042037,0.0004819171,0.00022599923,0.00012642739,0.000022382366,0.000009900518,0.00012362559],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99820065,0.00013211294,0.0009305156,0.0003729565,0.00012586876,0.00023787934],"domain_scores_gemma":[0.9924574,0.00679398,0.00027417488,0.00020930948,0.0002096633,0.00005547278],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0016750635,0.00017611234,0.00057092693,0.000036178997,0.000066117886,0.000021980464,0.000110105684,0.00015654872,0.000100385216],"category_scores_gemma":[0.02365306,0.00007642035,0.00013838401,0.00038419018,0.00028543887,0.00006809666,0.000117825424,0.00026017803,8.083873e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014460188,0.0004493649,0.14490105,0.000793695,0.0007898307,0.00022474263,0.0009166213,0.00020573214,0.050896898,0.0027455913,0.0065031927,0.7901273],"study_design_scores_gemma":[0.0032101402,0.006119193,0.21718024,0.0112013025,0.0021524606,0.00038296936,0.04484161,0.053858805,0.052489966,0.053920574,0.5528356,0.0018071551],"about_ca_topic_score_codex":0.0002030262,"about_ca_topic_score_gemma":0.000020605701,"teacher_disagreement_score":0.7883201,"about_ca_system_score_codex":0.000018622903,"about_ca_system_score_gemma":0.00004465302,"threshold_uncertainty_score":0.9845711},"labels":[],"label_agreement":null},{"id":"W4408727992","doi":"10.1016/j.biologicals.2025.101821","title":"Global availability of critical reagents for biologicals testing - Current status, challenges and possible solutions","year":2025,"lang":"en","type":"article","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Humane Society International","keywords":"Current (fluid); Biochemical engineering; Risk analysis (engineering); Computational biology; Data science; Biology; Medicine; Computer science; Engineering; Oceanography; Geology","score_opus":0.20636856003758755,"score_gpt":0.41314882603169506,"score_spread":0.2067802659941075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408727992","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.40368524,0.5661851,0.0077107656,0.0070640743,0.0020102756,0.0017696493,0.002619106,0.00030692085,0.008648849],"genre_scores_gemma":[0.98648363,0.003711213,0.009370865,0.00021663558,0.000026909727,0.00006227149,0.000029668787,0.0000032797118,0.00009554655],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99784714,0.00049670663,0.00051845005,0.00053983484,0.000024286757,0.00057357305],"domain_scores_gemma":[0.99677056,0.002621735,0.00009678305,0.00024114824,0.00021549193,0.000054284254],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0011163185,0.00019625324,0.0005297743,0.00004529968,0.00019600912,0.000010003169,0.00018630919,0.0004734519,0.00010819189],"category_scores_gemma":[0.0090299165,0.00012286325,0.00013094107,0.00019627312,0.001332787,0.000028456092,0.0002755363,0.00014940488,0.0000062692466],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037150164,0.0014885461,0.050013486,0.00047878345,0.0002188377,8.973336e-7,0.00002717505,3.0303238e-7,0.067888275,0.19919693,0.00232028,0.67799497],"study_design_scores_gemma":[0.0017051741,0.0021679641,0.6671163,0.00027494782,0.0003135911,0.000012426688,0.00024561558,0.00004481867,0.012574324,0.22986248,0.08513083,0.0005515273],"about_ca_topic_score_codex":0.000011506244,"about_ca_topic_score_gemma":0.000005113696,"teacher_disagreement_score":0.67744344,"about_ca_system_score_codex":0.00003555855,"about_ca_system_score_gemma":0.00005735871,"threshold_uncertainty_score":0.99931747},"labels":[],"label_agreement":null},{"id":"W4408751013","doi":"10.1016/j.biologicals.2025.101826","title":"Multiple factors shape technology transfer for the development and manufacture of vaccines in Latin America and the Caribbean","year":2025,"lang":"en","type":"review","venue":"Biologicals","topic":"Innovation and Socioeconomic Development","field":"Business, Management and Accounting","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"EduCanada; World Health Organization","keywords":"Latin Americans; Technology transfer; Caribbean region; Virology; Biology; Political science; Business; International trade","score_opus":0.046554294992043097,"score_gpt":0.275252695328795,"score_spread":0.22869840033675187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408751013","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.018005244,0.9751471,0.0002750567,0.002288509,0.00025422103,0.0034142788,0.000031307998,0.000055105367,0.0005291626],"genre_scores_gemma":[0.03265031,0.9646114,0.00047198278,0.0010347802,0.00009554614,0.00068018987,0.00016138743,0.000016618824,0.0002777742],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990094,0.000019137378,0.0005479105,0.00023709553,0.00003566533,0.0001507967],"domain_scores_gemma":[0.9989113,0.0007522588,0.00018221089,0.00010905467,0.00004200341,0.0000031634452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003559064,0.0002222286,0.00081275176,0.00019707285,0.000137792,0.00004209257,0.00022302948,0.00023520147,0.000038597613],"category_scores_gemma":[0.00023401914,0.00009281594,0.00007944236,0.0002545545,0.00015304828,0.000031705647,0.00013818481,0.0001463599,0.0000018102002],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001309176,0.000012025977,0.0014832314,0.0021290274,0.00008645974,1.482353e-7,0.00011480394,2.7608854e-7,2.7784426e-7,0.00804025,0.00015932607,0.98796105],"study_design_scores_gemma":[0.00042659926,0.000003063338,0.0037067619,0.00037223828,0.000063168285,1.4800743e-7,0.00042311466,0.000021880469,0.0000018168903,0.00036205573,0.9944828,0.00013636673],"about_ca_topic_score_codex":0.000019790346,"about_ca_topic_score_gemma":0.000036512192,"teacher_disagreement_score":0.99432343,"about_ca_system_score_codex":0.000018640325,"about_ca_system_score_gemma":0.000041202857,"threshold_uncertainty_score":0.37849241},"labels":[],"label_agreement":null},{"id":"W4414163940","doi":"10.1016/j.biologicals.2025.101859","title":"Report of the fourth conference on next-generation sequencing (NGS) for adventitious virus detection in biologics for humans and animals: Validation and implementation of NGS","year":2025,"lang":"en","type":"article","venue":"Biologicals","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"World Health Organization","keywords":"Standardization; Food and drug administration; Guideline; Alliance; Harmonization; Key (lock)","score_opus":0.16485399598810574,"score_gpt":0.34340958759467777,"score_spread":0.17855559160657203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414163940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99813396,0.000109015375,0.0005290252,0.00023990133,0.000059535425,0.0007790301,0.00008114425,0.000012113512,0.000056284676],"genre_scores_gemma":[0.9992932,0.00021588938,0.00023101195,0.00004531645,0.00003189667,0.00014110802,0.000028334667,4.2275246e-7,0.000012815936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926925,0.000071126444,0.00031192644,0.00021021372,0.00004136792,0.00009611846],"domain_scores_gemma":[0.99938035,0.00022790126,0.00022737043,0.00003301593,0.00012233603,0.000009040891],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043053206,0.00007956161,0.00015871332,0.000021093769,0.00019026107,0.0000165243,0.00004925397,0.00008218627,0.000007764116],"category_scores_gemma":[0.00028745076,0.000030683255,0.0000470057,0.00014481516,0.0000947334,0.000045390738,0.000040013776,0.000032772234,6.989959e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033752982,0.000017792097,0.017654493,0.000015382575,0.000009069927,5.7009387e-8,0.000032292577,0.0000041323774,0.961103,0.0041276435,0.000011301057,0.016991058],"study_design_scores_gemma":[0.0002962602,0.0015559343,0.37350473,0.00004056773,0.000029878009,0.0000025915824,0.0010850461,0.00030069135,0.61269355,0.009972988,0.00041060854,0.00010719214],"about_ca_topic_score_codex":0.00033046864,"about_ca_topic_score_gemma":0.0026283122,"teacher_disagreement_score":0.35585022,"about_ca_system_score_codex":0.00003132373,"about_ca_system_score_gemma":0.000008409011,"threshold_uncertainty_score":0.14666599},"labels":[],"label_agreement":null},{"id":"W4415103904","doi":"10.1016/j.biologicals.2025.101862","title":"Conference report WHO informal consultation on the draft WHO Guideline on the phasing out of animal tests for the quality control of biological products","year":2025,"lang":"en","type":"article","venue":"Biologicals","topic":"World Trade Organization Law","field":"Social Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health Canada; Ministry of Public Health; National Institute of Food and Drug Safety Evaluation; National Centre for the Replacement, Refinement and Reduction of Animals in Research; U.S. Food and Drug Administration; National Institutes for Food and Drug Control; National Centre for the Replacement Refinement and Reduction of Animals in Research; Ministry of Food and Drug Safety; Agence Nationale de Sécurité du Médicament et des Produits de Santé; World Health Organization; Merck","keywords":"Guideline; Quality (philosophy); Control (management); Product (mathematics); Quality control; Protocol (science); Animal testing","score_opus":0.15803267520296815,"score_gpt":0.42003997461089715,"score_spread":0.262007299407929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415103904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75209635,0.00011713182,0.0027272694,0.22941095,0.00034041618,0.0030806328,0.00012569987,0.00007843601,0.012023146],"genre_scores_gemma":[0.99691194,0.000035137124,0.00012350129,0.002379872,0.00010839611,0.000052375923,0.00001346854,0.0000028518068,0.0003724451],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.9978564,0.00069073564,0.00076990447,0.00023187534,0.00024582568,0.00020528863],"domain_scores_gemma":[0.99027854,0.0079341335,0.00059152406,0.00030723252,0.00086467696,0.000023891726],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.00483786,0.00012001773,0.00028932543,0.000024540404,0.0004889516,0.00004614326,0.00045022304,0.00012653005,0.0001040091],"category_scores_gemma":[0.042551592,0.000046982103,0.000071803144,0.0003806091,0.001272584,0.000049354847,0.000044381206,0.00012406497,0.0000034617715],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025631633,0.00009615558,0.0058185235,0.000007451456,0.000043155,3.9645147e-7,0.001124385,0.00001490296,0.013738774,0.9755641,0.0024010697,0.0009347594],"study_design_scores_gemma":[0.0025304754,0.00221485,0.51899874,0.0002963421,0.0001337133,0.000002241662,0.009703962,0.00064761384,0.06768965,0.012342265,0.38488457,0.00055557647],"about_ca_topic_score_codex":0.00007296111,"about_ca_topic_score_gemma":0.000052228097,"teacher_disagreement_score":0.96322185,"about_ca_system_score_codex":0.000022986842,"about_ca_system_score_gemma":0.00022772052,"threshold_uncertainty_score":0.9655134},"labels":[],"label_agreement":null},{"id":"W791093694","doi":"10.1016/j.biologicals.2015.05.013","title":"The regulation of cell therapy products in Canada","year":2015,"lang":"en","type":"article","venue":"Biologicals","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Harmonization; Business; Transplantation; Regulatory authority; Product (mathematics); Risk analysis (engineering); Food and drug administration; Biotechnology; Medicine; Biology; Political science; Public administration","score_opus":0.08397976924490445,"score_gpt":0.28834345700202263,"score_spread":0.20436368775711816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W791093694","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.979261,0.001507235,0.000008062497,0.01757193,0.00013058395,0.0002132055,0.0000012322232,0.0000050649905,0.0013016898],"genre_scores_gemma":[0.9990841,0.00022914707,0.00015810793,0.00022540979,0.000053385556,0.0000036192791,0.0000094750785,0.000001637331,0.00023510886],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99949104,0.000052665135,0.00015114571,0.00007858487,0.00014874442,0.000077802586],"domain_scores_gemma":[0.99963045,0.000067032175,0.00005349535,0.0001067596,0.000097780525,0.000044471086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045824182,0.000035374997,0.00009212728,0.000011120194,0.000014879914,0.0000016075647,0.00003874735,0.00006726242,0.000010186686],"category_scores_gemma":[0.00014280259,0.000014948691,0.000010618003,0.00012742083,0.00014422098,0.0000061051455,0.000009763639,0.00006794799,0.0000010785716],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010079676,0.00036220992,0.07167177,0.00008361186,0.00003210358,0.000009484093,0.00045684777,0.000050704577,0.688369,0.009755717,0.015126299,0.2130743],"study_design_scores_gemma":[0.0010413653,0.00030529374,0.87288177,0.000023832903,0.0000031436507,0.00000272876,0.00017305817,0.00030642858,0.048925295,0.005186692,0.071090624,0.0000597472],"about_ca_topic_score_codex":0.0716397,"about_ca_topic_score_gemma":0.039692447,"teacher_disagreement_score":0.80121005,"about_ca_system_score_codex":0.00006170043,"about_ca_system_score_gemma":0.00060048106,"threshold_uncertainty_score":0.97783065},"labels":[],"label_agreement":null}]}