{"meta":{"query_hash":"94f1bf1dbd85","filters":{"venue":"Cell & Bioscience"},"cohort_total":45,"direct_labels_cover":0,"predictions_cover":45,"exported":45,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/94f1bf1dbd85","api":"https://metacan.xera.ac/api/v1/cohort?venue=Cell+%26+Bioscience"},"results":[{"id":"W2096611464","doi":"10.1186/2045-3701-2-28","title":"The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective","year":2012,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research","keywords":"Wnt signaling pathway; TCF7L2; Glucose homeostasis; Biology; Cell biology; Crosstalk; LRP6; Signal transduction; LRP5; Transcription factor; Genetics; Diabetes mellitus; Endocrinology; Insulin resistance; Gene; Single-nucleotide polymorphism","score_opus":0.03313347163852726,"score_gpt":0.2586161532402676,"score_spread":0.22548268160174034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096611464","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014998451,0.9863566,0.00061162864,0.009967758,0.000822695,0.000003383647,0.00003075211,0.000010775444,0.00069652125],"genre_scores_gemma":[0.013148729,0.9743828,0.0009246903,0.0046583316,0.0062778722,0.000013862518,0.00007084662,0.0000064266887,0.00051638123],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9991991,0.00020352517,0.00015900943,0.00019312004,0.00014832268,0.00009699005],"domain_scores_gemma":[0.9972698,0.0014854484,0.0002859091,0.00014635167,0.0005822525,0.00023015591],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003342457,0.0006687706,0.0018386049,0.0013476561,0.0005611299,0.0022421917,0.0013143453,0.0029443842,0.0015832975],"category_scores_gemma":[0.0022963034,0.00033294628,0.0008913408,0.0015497649,0.0026059973,0.0038633856,0.0013655677,0.0038911318,0.00051605114],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013803858,0.00026901887,0.0114362305,0.015203851,0.00053476816,0.0031038208,0.00083991344,0.00082560116,0.010788668,0.047376037,0.03178373,0.8764579],"study_design_scores_gemma":[0.0001616818,0.00072300964,0.016177645,0.009045546,0.0014026297,0.01106622,0.0033980513,0.0018558287,0.004769039,0.0912434,0.85991096,0.00024599492],"about_ca_topic_score_codex":0.0014604721,"about_ca_topic_score_gemma":0.001312322,"teacher_disagreement_score":0.003342457,"about_ca_system_score_codex":0.000845336,"about_ca_system_score_gemma":0.0019680518,"threshold_uncertainty_score":0.01767683},"labels":[],"label_agreement":null},{"id":"W2101020904","doi":"10.1186/s13578-015-0035-9","title":"Exogenous hydrogen sulfide restores cardioprotection of ischemic post-conditioning via inhibition of mPTP opening in the aging cardiomyocytes","year":2015,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University","funders":"National Natural Science Foundation of China","keywords":"Cardioprotection; Protein kinase B; PI3K/AKT/mTOR pathway; Cell biology; Chemistry; Apoptosis; Cytochrome c; Pharmacology; Biology; Ischemia; Biochemistry; Internal medicine; Medicine","score_opus":0.016276026796921687,"score_gpt":0.24426547637926074,"score_spread":0.22798944958233905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101020904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994158,0.0033738227,0.001560164,0.000107215405,0.00006509855,0.000026017316,0.00012747174,0.000083444356,0.00049877324],"genre_scores_gemma":[0.99624205,0.0015175344,0.0009941942,0.00008131632,0.000030437543,0.00002503046,0.00021692872,0.000012745791,0.00087974686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995434,0.000007502675,0.000008104253,0.000009621514,0.0000096743,0.000010787625],"domain_scores_gemma":[0.99993026,0.000005968848,0.000020546044,0.000008925752,0.000011112601,0.000023287026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013039849,0.0004038787,0.00034665506,0.00015924044,0.00012001636,0.00014362397,0.0001723374,0.00021016123,0.00082353404],"category_scores_gemma":[0.000099147524,0.00009469242,0.00027794534,0.00009614934,0.00019665158,0.00026027998,0.0001990134,0.00044899137,0.00010551044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009010821,0.00010606842,0.00023295441,0.00012736006,0.000019986535,0.00010122722,0.000024496916,0.0000615994,0.99514824,0.000050742383,0.000058490186,0.0031677808],"study_design_scores_gemma":[0.00012869551,0.0024655845,0.008840867,0.000016168326,0.00008640414,0.00020219498,0.000056713172,0.00063309947,0.98572344,0.000089295725,0.0017484223,0.0000091545],"about_ca_topic_score_codex":0.0004639288,"about_ca_topic_score_gemma":0.000726815,"teacher_disagreement_score":0.00082353404,"about_ca_system_score_codex":0.000108780776,"about_ca_system_score_gemma":0.0002213805,"threshold_uncertainty_score":0.0027549863},"labels":[],"label_agreement":null},{"id":"W2102983882","doi":"10.1186/s13578-015-0003-4","title":"Mediation of exogenous hydrogen sulfide in recovery of ischemic post-conditioning-induced cardioprotection via down-regulating oxidative stress and up-regulating PI3K/Akt/GSK-3β pathway in isolated aging rat hearts","year":2015,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University","funders":"National Natural Science Foundation of China","keywords":"Cardioprotection; Oxidative stress; Protein kinase B; PI3K/AKT/mTOR pathway; Cystathionine gamma-lyase; Medicine; Reactive oxygen species; Pharmacology; LY294002; Internal medicine; Chemistry; Apoptosis; Endocrinology; Ischemia; Cell biology; Biology; Biochemistry; Cystathionine beta synthase; Cysteine; Enzyme","score_opus":0.012151965487419446,"score_gpt":0.23154406420257045,"score_spread":0.219392098715151,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102983882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934962,0.004097003,0.0014122822,0.00012778073,0.00007756712,0.000033951063,0.00013163741,0.00007906313,0.0005445464],"genre_scores_gemma":[0.9947996,0.0024301081,0.0012640076,0.00009480256,0.000036597325,0.00006320568,0.00024618444,0.000011703266,0.001053712],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999294,0.0000094359475,0.0000103542725,0.000016104108,0.000011674129,0.000023027276],"domain_scores_gemma":[0.99992883,0.0000043789487,0.000022492204,0.000008037146,0.000008951151,0.000027245902],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019355079,0.0005766389,0.00044112382,0.00022952225,0.00014086845,0.0001700108,0.00021445913,0.00022893673,0.000979822],"category_scores_gemma":[0.00009227274,0.00016733524,0.0003845061,0.00010766449,0.00031342515,0.00030464088,0.00023407312,0.00066319946,0.000107494816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024498191,0.00029415693,0.00045624463,0.00023440608,0.000033723725,0.00014970188,0.00004602472,0.000090191825,0.9916524,0.0001160899,0.000091553615,0.0043857354],"study_design_scores_gemma":[0.0003603642,0.0046313624,0.014208878,0.00002870969,0.00015015223,0.00023330297,0.000083909166,0.0010389204,0.97751063,0.00016180395,0.001577837,0.000014053876],"about_ca_topic_score_codex":0.00046262058,"about_ca_topic_score_gemma":0.0007727904,"teacher_disagreement_score":0.000979822,"about_ca_system_score_codex":0.0001401745,"about_ca_system_score_gemma":0.00032421263,"threshold_uncertainty_score":0.0032777786},"labels":[],"label_agreement":null},{"id":"W2112780416","doi":"10.1186/2045-3701-4-57","title":"COUP-TFII and AKT are cancer targets pursued by SCBA award winners","year":2014,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Protein kinase B; Political science; Library science; Management; Cancer research; Psychology; Medicine; Biology; Signal transduction; Genetics; Computer science; Economics","score_opus":0.006618809726742728,"score_gpt":0.22540368508381994,"score_spread":0.21878487535707722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112780416","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.108218454,0.3653076,0.0029007604,0.21814635,0.17152059,0.00023159762,0.0019296793,0.0004985102,0.13124646],"genre_scores_gemma":[0.27210918,0.2743702,0.0032720636,0.029186083,0.09401232,0.00022950524,0.00466189,0.00031804395,0.32184076],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987564,0.0001343229,0.000051917377,0.0000900203,0.000570342,0.00039700072],"domain_scores_gemma":[0.9961117,0.00016552511,0.00021867825,0.00006364944,0.0011922821,0.002248158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024336467,0.0005108526,0.00051621516,0.0014508042,0.0013476638,0.0043762135,0.00048253132,0.0019073517,0.018001191],"category_scores_gemma":[0.002249439,0.00016378141,0.00032690636,0.0013856838,0.00053148234,0.0016924387,0.0028960302,0.0015215939,0.0059595546],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068554404,0.00011201427,0.007190581,0.0007358406,0.00006516311,0.0004442808,0.00026201134,0.00014886342,0.011257668,0.009983167,0.7166618,0.25245312],"study_design_scores_gemma":[0.000042942174,0.00021431792,0.013199519,0.00026822003,0.000046886147,0.00051239505,0.00055552315,0.00019860582,0.004552538,0.0025828301,0.97779924,0.000026937163],"about_ca_topic_score_codex":0.0005464327,"about_ca_topic_score_gemma":0.0023156174,"teacher_disagreement_score":0.018001191,"about_ca_system_score_codex":0.0015658925,"about_ca_system_score_gemma":0.0021171565,"threshold_uncertainty_score":0.060220003},"labels":[],"label_agreement":null},{"id":"W2113866616","doi":"10.1186/2045-3701-2-18","title":"C. elegans PAT-9 is a nuclear zinc finger protein critical for the assembly of muscle attachments","year":2012,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; University of Illinois at Urbana-Champaign; National Institutes of Health","keywords":"Biology; Zinc finger; Caenorhabditis elegans; Gene; Mutant; Genetic screen; Genetics; Sarcomere; Positional cloning; Phenotype; Cell biology; Molecular biology; Myocyte; Transcription factor","score_opus":0.01802749941641546,"score_gpt":0.27656992382437473,"score_spread":0.25854242440795927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113866616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863896,0.0013156331,0.0072252667,0.00008209304,0.000042541327,0.00006771543,0.0020189756,0.00037180353,0.0024863386],"genre_scores_gemma":[0.9825324,0.0006906872,0.010204289,0.000037614358,0.000008358686,0.000050368864,0.0019905,0.000052486837,0.0044334033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992824,0.0000024614687,0.0000051940106,0.000025107602,0.000027410937,0.000011562716],"domain_scores_gemma":[0.9999275,0.000005594603,0.000024402781,0.000006059382,0.000011687698,0.000024711539],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047512116,0.0004976834,0.0001431509,0.00024443827,0.00030623726,0.00017573501,0.00031032547,0.00028392966,0.0014586131],"category_scores_gemma":[0.00006346588,0.00011506628,0.00019882071,0.00009511577,0.00021917546,0.00011808032,0.00025003531,0.00030172066,0.0008258401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028969018,0.00000865675,0.00022804114,0.000030384383,0.000001986273,0.000120387296,0.0000037140471,0.00004277111,0.99859244,0.000036657202,0.000049357157,0.0008566525],"study_design_scores_gemma":[0.000019033081,0.0001661708,0.021703728,0.000028090144,0.000025053872,0.0012778974,0.00003276825,0.001569513,0.9682552,0.000077885736,0.0068318225,0.000012857025],"about_ca_topic_score_codex":0.0014906413,"about_ca_topic_score_gemma":0.0022310768,"teacher_disagreement_score":0.0014906413,"about_ca_system_score_codex":0.00031384974,"about_ca_system_score_gemma":0.00031470548,"threshold_uncertainty_score":0.0048795342},"labels":[],"label_agreement":null},{"id":"W2121443197","doi":"10.1186/2045-3701-1-15","title":"Subretinal gene delivery using helper-dependent adenoviral vectors","year":2011,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Canada Research Chairs; Toronto Rehabilitation Institute; University of British Columbia; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Gene delivery; Viral vector; Gene transfer; Virology; Genetic enhancement; Biology; Gene; Computational biology; Genetics; Recombinant DNA","score_opus":0.02832942162602019,"score_gpt":0.21963753389832255,"score_spread":0.19130811227230235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121443197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7570814,0.012265384,0.21012264,0.00084168126,0.0005542452,0.00071495736,0.0009851034,0.0023258487,0.015108703],"genre_scores_gemma":[0.88135606,0.009481675,0.08477225,0.00015895921,0.00010794871,0.0001708962,0.0009289587,0.00021788006,0.02280533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997713,0.000021783851,0.000019113748,0.00004865943,0.00009699026,0.000042198906],"domain_scores_gemma":[0.99986434,0.00003217973,0.000035100005,0.00002423105,0.0000179742,0.000026240323],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032546968,0.00040618668,0.0003166068,0.00032649556,0.00022031921,0.0006188189,0.0003702941,0.00039647767,0.0012314088],"category_scores_gemma":[0.0002033942,0.00026126753,0.00027163097,0.00016237076,0.00035381177,0.00044304974,0.0003989061,0.000961288,0.0009997955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060352642,0.000031396055,0.00017228058,0.00006453392,0.000005520791,0.00017036928,0.00006435053,0.00010147556,0.9865487,0.0011688608,0.00016438925,0.0114477],"study_design_scores_gemma":[0.000024460904,0.00024328353,0.00047180953,0.000007913184,0.000017185137,0.0006605726,0.000029595041,0.00059097726,0.98249346,0.000174909,0.015275503,0.000010327964],"about_ca_topic_score_codex":0.00059103535,"about_ca_topic_score_gemma":0.0008641383,"teacher_disagreement_score":0.0012314088,"about_ca_system_score_codex":0.00031278693,"about_ca_system_score_gemma":0.00051308057,"threshold_uncertainty_score":0.004119456},"labels":[],"label_agreement":null},{"id":"W2127851467","doi":"10.1186/2045-3701-1-20","title":"Role of dendritic cells in the induction of regulatory T cells","year":2011,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":157,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Foundation Fighting Blindness","keywords":"FOXP3; Cell biology; Regulatory T cell; Immune system; Biology; Dendritic cell; Immune tolerance; Regulatory B cells; Retinoic acid; IL-2 receptor; Interleukin 10; Immunology; T cell; Cell culture; Genetics","score_opus":0.014254422383959818,"score_gpt":0.1996350856676227,"score_spread":0.18538066328366287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127851467","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13391347,0.77855843,0.045460742,0.0033124054,0.0021735805,0.00036019334,0.0005279735,0.000343366,0.035349913],"genre_scores_gemma":[0.674941,0.29522225,0.015169097,0.0015710777,0.0014927714,0.00022805057,0.00031711394,0.000058165395,0.011000439],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999603,0.0001054525,0.00003412719,0.00008267556,0.00010427355,0.00007052797],"domain_scores_gemma":[0.9998381,0.000047646652,0.000026406397,0.000011173454,0.0000385705,0.000037923877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054752623,0.0003412895,0.0006149333,0.00041513625,0.000256465,0.0008440917,0.0003456336,0.0008524159,0.0011879286],"category_scores_gemma":[0.0003135656,0.00014281768,0.00029017855,0.0002839137,0.00043733648,0.0004276555,0.00041360778,0.0011365289,0.0009680322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065232225,0.00020220544,0.0019154953,0.0028882625,0.000046288787,0.0015955888,0.00021275952,0.00084724743,0.79934883,0.014063218,0.0025832409,0.1756445],"study_design_scores_gemma":[0.00027806018,0.002083878,0.009462846,0.000765224,0.00020825547,0.00448628,0.00039568442,0.0035240827,0.6118268,0.016542807,0.3503589,0.000067276866],"about_ca_topic_score_codex":0.00018926065,"about_ca_topic_score_gemma":0.00018048588,"teacher_disagreement_score":0.0011879286,"about_ca_system_score_codex":0.0003919433,"about_ca_system_score_gemma":0.00036994778,"threshold_uncertainty_score":0.003973961},"labels":[],"label_agreement":null},{"id":"W2135434526","doi":"10.1186/2045-3701-2-22","title":"The protective effect of peroxiredoxin II on oxidative stress induced apoptosis in pancreatic β-cells","year":2012,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Apoptosis; Oxidative stress; Proinflammatory cytokine; Cell biology; Gene knockdown; Chemistry; Peroxiredoxin; Biology; Immunology; Inflammation; Biochemistry","score_opus":0.008030983324585213,"score_gpt":0.25095904541183806,"score_spread":0.24292806208725284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135434526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865731,0.0074337353,0.004033348,0.00019679224,0.000115041155,0.000049111102,0.00026499075,0.00008270007,0.0012512688],"genre_scores_gemma":[0.9903762,0.004632976,0.002848738,0.00013460753,0.000035514364,0.00005651108,0.00063283346,0.000013113713,0.0012695014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999064,0.000018150264,0.000012924411,0.000023167322,0.000015835758,0.000023556155],"domain_scores_gemma":[0.99990547,0.000013435621,0.000023118411,0.0000140197535,0.000018364964,0.000025592508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022894786,0.00037629012,0.00033510468,0.00016275207,0.00012345565,0.00025137246,0.00015150366,0.00022880774,0.00087085605],"category_scores_gemma":[0.00013342014,0.00013501568,0.00035665854,0.00013193098,0.00015306185,0.00030410028,0.00018709751,0.0007939954,0.00013886766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029933645,0.000052273426,0.00022631805,0.0001270927,0.000012481883,0.0000695065,0.000018849865,0.00003366578,0.997218,0.000049368075,0.000041867945,0.0018512217],"study_design_scores_gemma":[0.000061546976,0.001235323,0.0073905694,0.000020160558,0.000039945437,0.00044329886,0.000051362327,0.00041799093,0.9883652,0.000069354515,0.0019005312,0.000004776971],"about_ca_topic_score_codex":0.00016718262,"about_ca_topic_score_gemma":0.00015228504,"teacher_disagreement_score":0.00087085605,"about_ca_system_score_codex":0.000095662166,"about_ca_system_score_gemma":0.00016901239,"threshold_uncertainty_score":0.0029132962},"labels":[],"label_agreement":null},{"id":"W2144004702","doi":"10.1186/s13578-015-0023-0","title":"Transient blocking of NK cell function with small molecule inhibitors for helper dependant adenoviral vector-mediated gene delivery","year":2015,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"Garron Family Cancer Centre; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Biology; Immune system; Gene delivery; Janus kinase 3; Cell biology; Cytokine; Genetic enhancement; Viral vector; Interleukin 21; Immunology; Cell culture; T cell; Transfection; Gene","score_opus":0.01766855660617666,"score_gpt":0.19852644049482238,"score_spread":0.1808578838886457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144004702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9606774,0.0068458235,0.026939223,0.0002504443,0.00027084575,0.00040525093,0.00077861734,0.0003783014,0.0034542568],"genre_scores_gemma":[0.97971606,0.0022372208,0.013305883,0.00006173472,0.000032098975,0.00027590847,0.00056595425,0.000033862725,0.0037711377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973553,0.000045417015,0.000032608616,0.000057649835,0.00006494064,0.000063734464],"domain_scores_gemma":[0.99990046,0.00003157134,0.000023582943,0.000019956737,0.000009231155,0.000015220151],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027060736,0.0003720419,0.00046279433,0.00018515352,0.0001582961,0.0003999031,0.00035520707,0.00028376348,0.00177746],"category_scores_gemma":[0.00013752382,0.00015315923,0.000321163,0.00016739221,0.00030428416,0.00029179372,0.0001963037,0.0009071196,0.00039111264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007482503,0.000049378657,0.000054513566,0.000054347718,0.000004486535,0.000026122018,0.000014319173,0.00006562122,0.99795794,0.00019324968,0.000053827414,0.0014513138],"study_design_scores_gemma":[0.000021314832,0.00022102485,0.00032618007,0.0000034273244,0.000012988233,0.00007601005,0.000006894,0.00055175467,0.99633515,0.000021109243,0.0024217637,0.0000025252375],"about_ca_topic_score_codex":0.0005060302,"about_ca_topic_score_gemma":0.0011093456,"teacher_disagreement_score":0.00177746,"about_ca_system_score_codex":0.00038659506,"about_ca_system_score_gemma":0.00030076774,"threshold_uncertainty_score":0.005946219},"labels":[],"label_agreement":null},{"id":"W2144509907","doi":"10.1186/2045-3701-3-40","title":"Enhancing myogenic differentiation of pluripotent stem cells with small molecule inducers","year":2013,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Induced pluripotent stem cell; Biology; Stem cell; Lineage (genetic); Cell biology; Cellular differentiation; Inducer; Chromatin; Population; Small molecule; Embryonic stem cell; Genetics; Gene; Medicine","score_opus":0.012576375751614913,"score_gpt":0.2125935538342735,"score_spread":0.2000171780826586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144509907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8695869,0.011053109,0.10778641,0.00050625746,0.00015771744,0.00031460167,0.00048671447,0.00063581776,0.0094725145],"genre_scores_gemma":[0.9540112,0.00847155,0.033442684,0.0001520875,0.000052086783,0.00015924728,0.00032662775,0.00007173725,0.0033127044],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999866,0.00003103294,0.000015658097,0.000021818623,0.000048134392,0.00001733815],"domain_scores_gemma":[0.99987173,0.00006360579,0.000031886728,0.000009125904,0.000011571317,0.000012006579],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027575245,0.000312883,0.00019708484,0.0003081641,0.00009973174,0.00023828234,0.00013921078,0.00020094802,0.001153964],"category_scores_gemma":[0.0002402133,0.00014595134,0.00020007546,0.00018493016,0.00018580699,0.0002656917,0.00027270915,0.00044828394,0.00029499226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001477329,0.00001241593,0.000034705998,0.00006321055,0.0000019655668,0.000027422462,0.000012778926,0.00015864165,0.9970162,0.0004070186,0.000025162419,0.0022256833],"study_design_scores_gemma":[0.000010675627,0.00011846479,0.00030579508,0.000008323041,0.000010136149,0.00005999514,0.000008607921,0.0009363077,0.99486226,0.00009892328,0.0035778063,0.0000027724436],"about_ca_topic_score_codex":0.00011711171,"about_ca_topic_score_gemma":0.00025294622,"teacher_disagreement_score":0.001153964,"about_ca_system_score_codex":0.0001579939,"about_ca_system_score_gemma":0.00016990789,"threshold_uncertainty_score":0.003860414},"labels":[],"label_agreement":null},{"id":"W2144525948","doi":"10.1186/2045-3701-3-30","title":"Cell density during differentiation can alter the phenotype of bone marrow-derived macrophages","year":2013,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs","funders":"Hospital for Sick Children","keywords":"Proinflammatory cytokine; CD11c; Macrophage; Bone marrow; Integrin alpha M; Population; Cell biology; Cell; Tumor necrosis factor alpha; Immunology; Biology; Phenotype; Chemistry; Inflammation; Medicine; In vitro; Biochemistry; Gene","score_opus":0.0055241755315866515,"score_gpt":0.19023473018123976,"score_spread":0.1847105546496531,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144525948","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939306,0.0018836022,0.0017261662,0.000113912196,0.00004835113,0.000039363735,0.00020643974,0.00003236296,0.0020192016],"genre_scores_gemma":[0.9943873,0.0014396524,0.0024103664,0.00015497372,0.000034475426,0.00007174593,0.00043692093,0.000021822652,0.001042582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99947554,0.00012269242,0.00007768511,0.000064301224,0.00014872836,0.00011113201],"domain_scores_gemma":[0.9995552,0.00017393805,0.00006909731,0.000035181096,0.00010681984,0.000059759284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004176206,0.0002832367,0.00026875714,0.00022779404,0.00016593891,0.00055900606,0.0002713455,0.00033424576,0.0010666086],"category_scores_gemma":[0.00048668063,0.0001998701,0.0002080447,0.00017313061,0.0002260101,0.000236046,0.000372721,0.00070066005,0.00050077244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002033183,0.00005808702,0.0013150679,0.0000587515,0.0000066719176,0.00006819909,0.00008442097,0.000060281305,0.996496,0.00006794448,0.00007300538,0.0015081771],"study_design_scores_gemma":[0.000028162138,0.00080141774,0.020699404,0.00004988486,0.00005186814,0.00029914366,0.00019250413,0.0008124506,0.9739545,0.000087629516,0.0030066038,0.000016412876],"about_ca_topic_score_codex":0.0006119174,"about_ca_topic_score_gemma":0.0010412451,"teacher_disagreement_score":0.0010666086,"about_ca_system_score_codex":0.00025417676,"about_ca_system_score_gemma":0.00017749464,"threshold_uncertainty_score":0.0035681129},"labels":[],"label_agreement":null},{"id":"W2337516957","doi":"10.1186/s13578-016-0090-x","title":"Exogenous H2S contributes to recovery of ischemic post-conditioning-induced cardioprotection by decrease of ROS level via down-regulation of NF-κB and JAK2-STAT3 pathways in the aging cardiomyocytes","year":2016,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University","funders":"National Natural Science Foundation of China","keywords":"Cardioprotection; Viability assay; Chemistry; Apoptosis; Sodium hydrosulfide; Reactive oxygen species; Protein kinase B; Cytochrome c; Cystathionine beta synthase; Cell biology; Pharmacology; Biochemistry; Biology; Internal medicine; Cysteine; Medicine; Ischemia; Hydrogen sulfide; Enzyme","score_opus":0.012586465251079914,"score_gpt":0.22017754573757237,"score_spread":0.20759108048649244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2337516957","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903138,0.005992524,0.0020436745,0.00014798356,0.00010837567,0.000032083208,0.0002851199,0.000081683385,0.000994734],"genre_scores_gemma":[0.99561787,0.0018251076,0.00077404466,0.00007338256,0.000044536755,0.0000391252,0.00033012536,0.000011316842,0.0012845278],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999491,0.000005722474,0.000006930629,0.000010245835,0.000011672723,0.000016282187],"domain_scores_gemma":[0.9999453,0.0000032089458,0.000016071608,0.0000052834976,0.000008228922,0.000021912569],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001226043,0.00031965616,0.00029205534,0.00013986848,0.000114053524,0.00015034633,0.0001506122,0.00016776197,0.0015274951],"category_scores_gemma":[0.000069287154,0.00008011971,0.00030266796,0.00009165249,0.00019452265,0.00017753831,0.00013213568,0.00039882245,0.00017396662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011819842,0.000118363336,0.00045381935,0.0001312922,0.000016561336,0.0000859993,0.000018175891,0.000049818213,0.995082,0.000055450917,0.000101050726,0.0027054648],"study_design_scores_gemma":[0.00014390792,0.0019481744,0.018561097,0.000025016272,0.000098162694,0.0003262661,0.0000837756,0.000814516,0.9750838,0.00013023929,0.0027762174,0.000008804397],"about_ca_topic_score_codex":0.00029484354,"about_ca_topic_score_gemma":0.00040602178,"teacher_disagreement_score":0.0015274951,"about_ca_system_score_codex":0.000116546005,"about_ca_system_score_gemma":0.00020003408,"threshold_uncertainty_score":0.005109966},"labels":[],"label_agreement":null},{"id":"W2338677926","doi":"10.1186/s13578-016-0092-8","title":"Ammonium ions improve the survival of glutamine-starved hybridoma cells","year":2016,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Glutamine; Ammonium; Ammonium chloride; Apoptosis; Biology; Metabolism; Ammonium acetate; Cell culture; Cancer cell; Programmed cell death; Biochemistry; Glutamine synthetase; Chemistry; Amino acid; Cancer; Organic chemistry","score_opus":0.007840053348283789,"score_gpt":0.21715336302951477,"score_spread":0.209313309681231,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2338677926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910227,0.002808031,0.0035073152,0.00012929489,0.000082930266,0.000034601188,0.0005969889,0.00016904161,0.0016491315],"genre_scores_gemma":[0.9891578,0.001296391,0.0040287795,0.00013609962,0.000027241322,0.000040557483,0.0011781327,0.00006443143,0.0040704324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997985,0.00003606902,0.00003723364,0.000033354634,0.00006186282,0.000033107666],"domain_scores_gemma":[0.9997781,0.000048085243,0.00004391635,0.000023120341,0.000056556175,0.000050267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017393826,0.00041190875,0.000411065,0.00024563773,0.00014326123,0.00032646564,0.0003717354,0.00032411775,0.001164444],"category_scores_gemma":[0.00010317747,0.0000865977,0.00029490818,0.0001236306,0.00013806227,0.00019174459,0.0003251127,0.00041520552,0.00047591643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028881038,0.00004657044,0.00028678944,0.000044501776,0.000007732512,0.00005959319,0.000020034186,0.00004086954,0.9980459,0.000023850565,0.00004424727,0.0010911357],"study_design_scores_gemma":[0.000016323662,0.0007114237,0.00247517,0.0000067159135,0.00001978551,0.0002045702,0.000026529397,0.0002878373,0.9940432,0.000021064721,0.0021833114,0.000004151285],"about_ca_topic_score_codex":0.00041239182,"about_ca_topic_score_gemma":0.0006465797,"teacher_disagreement_score":0.001164444,"about_ca_system_score_codex":0.00020534142,"about_ca_system_score_gemma":0.00018434304,"threshold_uncertainty_score":0.003895402},"labels":[],"label_agreement":null},{"id":"W2345624579","doi":"10.1186/s13578-016-0098-2","title":"IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia","year":2016,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Effector; Stem cell; Cell biology; Adoptive cell transfer; Signal transduction; Biology; Cancer research; Immunology; Chemistry; T cell; Immune system","score_opus":0.01294281797370108,"score_gpt":0.2138403926947956,"score_spread":0.2008975747210945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2345624579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974245,0.0011233739,0.0007076323,0.000035338544,0.00001899762,0.000014800919,0.00013851919,0.00004494016,0.000491936],"genre_scores_gemma":[0.9973507,0.00047188596,0.0008486696,0.000052578234,0.000014660221,0.00003251538,0.00022570966,0.0000107628,0.0009926454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998491,0.000021725733,0.00002250706,0.000030790827,0.000026388409,0.000049531238],"domain_scores_gemma":[0.99986804,0.0000129380105,0.000053883294,0.000011388631,0.000012617708,0.00004108669],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012244657,0.00047932833,0.0003106472,0.000201068,0.000108316024,0.00024144725,0.00016428647,0.00027659268,0.0011957223],"category_scores_gemma":[0.00009155902,0.00011625408,0.00025677498,0.00008811006,0.00022684604,0.00021274571,0.0001987775,0.00087577687,0.00032440244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022519263,0.000044111883,0.00042503278,0.000058812668,0.0000037158945,0.00003776343,0.00001888124,0.000050459425,0.9982016,0.000034172066,0.000022349419,0.0008780232],"study_design_scores_gemma":[0.000058054018,0.0013815952,0.010725542,0.00003364475,0.00005177894,0.00036869317,0.00006120959,0.0006453711,0.9853639,0.000069742666,0.0012358034,0.0000046306004],"about_ca_topic_score_codex":0.00011795496,"about_ca_topic_score_gemma":0.0002570449,"teacher_disagreement_score":0.0011957223,"about_ca_system_score_codex":0.00018879079,"about_ca_system_score_gemma":0.00015106988,"threshold_uncertainty_score":0.0040001273},"labels":[],"label_agreement":null},{"id":"W2426783776","doi":"10.1186/s13578-016-0105-7","title":"Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts","year":2016,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; University Health Network; Toronto Western Hospital; Canada Research Chairs; St. Michael's Hospital","funders":"Canadian Arthritis Network; Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto","keywords":"Gene knockdown; Transcription factor; Downregulation and upregulation; Inflammation; Chemistry; Cyclooxygenase; Synovial membrane; Cancer research; Cell biology; Immunology; Biology; Apoptosis; Biochemistry; Enzyme; Gene","score_opus":0.010722907146305916,"score_gpt":0.23699319651886433,"score_spread":0.22627028937255841,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2426783776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853456,0.0061393073,0.00413471,0.00021309558,0.00011311141,0.000033346696,0.0014119268,0.00010777553,0.002500999],"genre_scores_gemma":[0.9911413,0.0012516723,0.001596227,0.00007518332,0.000014643458,0.000030112573,0.0011066515,0.000012976515,0.0047711874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999826,0.000019927982,0.000014574965,0.000036551588,0.000068691596,0.000034344044],"domain_scores_gemma":[0.9999267,0.000013686228,0.000018140232,0.0000139069,0.00001540853,0.000012210385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016891782,0.00029677624,0.00017258307,0.0002027272,0.00018830001,0.00022370754,0.00012750992,0.00019568198,0.0021189877],"category_scores_gemma":[0.00009932117,0.000105573126,0.0003274644,0.00015421199,0.00017536125,0.00012006101,0.00015544872,0.00033406322,0.0006190673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071238865,0.0000117149475,0.00034307298,0.00003313177,0.00000395706,0.00006655262,0.000011293995,0.000022600889,0.99862945,0.000044734228,0.000056753095,0.00070568867],"study_design_scores_gemma":[0.00002048931,0.00014762873,0.012456187,0.000008546918,0.000023478746,0.00051975815,0.000069432994,0.0006826947,0.98025745,0.000050487193,0.0057583833,0.0000055423875],"about_ca_topic_score_codex":0.00087310554,"about_ca_topic_score_gemma":0.0012965212,"teacher_disagreement_score":0.0021189877,"about_ca_system_score_codex":0.00026164495,"about_ca_system_score_gemma":0.00018241757,"threshold_uncertainty_score":0.007088661},"labels":[],"label_agreement":null},{"id":"W2513365840","doi":"10.1186/s13578-016-0111-9","title":"Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway","year":2016,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Ministry of Education, Science and Technology; National Research Foundation of Korea; Kangwon National University; National Research Foundation","keywords":"Induced pluripotent stem cell; Stem cell; Haematopoiesis; Estrogen receptor; Cell biology; Biology; Signal transduction; Embryonic stem cell; Genetics; Gene","score_opus":0.011230897926392184,"score_gpt":0.2446138491680292,"score_spread":0.23338295124163702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2513365840","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9747448,0.003659768,0.015047413,0.00016826889,0.00005862984,0.0000693642,0.0010804972,0.00018150531,0.0049897167],"genre_scores_gemma":[0.98781943,0.0015546738,0.0054484373,0.0001072464,0.000011005253,0.0000393138,0.0010398927,0.0000200075,0.003960116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999925,0.0000142096615,0.00000996332,0.000013104282,0.00002697904,0.000010750532],"domain_scores_gemma":[0.99996305,0.000007732211,0.000008679293,0.0000048445213,0.000008321599,0.000007300206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018000466,0.000248528,0.00013175748,0.00019175153,0.000065516724,0.00013258033,0.000096049,0.00016318393,0.0014661107],"category_scores_gemma":[0.00008643311,0.000065949425,0.0001659552,0.00014446938,0.000095725045,0.00010601854,0.00018848412,0.00024384285,0.00021360793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006668685,0.000020155312,0.00024885012,0.00005433808,0.00000565511,0.00007735449,0.000012405444,0.00014112315,0.99466574,0.00020181788,0.00008218408,0.004423745],"study_design_scores_gemma":[0.000023395105,0.0002887873,0.0031858713,0.000009184662,0.000030525895,0.00022159518,0.000013803402,0.000745937,0.989325,0.000095517185,0.0060574454,0.000003084882],"about_ca_topic_score_codex":0.00016341734,"about_ca_topic_score_gemma":0.00033044588,"teacher_disagreement_score":0.0014661107,"about_ca_system_score_codex":0.00009405419,"about_ca_system_score_gemma":0.00010952968,"threshold_uncertainty_score":0.0049046874},"labels":[],"label_agreement":null},{"id":"W2610936921","doi":"10.1186/s13578-017-0150-x","title":"Gene expression profiling discerns molecular pathways elicited by ligand signaling to enhance the specification of embryonic stem cells into skeletal muscle lineage","year":2017,"lang":"en","type":"review","venue":"Cell & Bioscience","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Myogenesis; Biology; Cell biology; Embryonic stem cell; Stem cell; Cellular differentiation; Progenitor cell; Signal transduction; Gene expression profiling; Skeletal muscle; Mesoderm; Transcriptome; Myocyte; Genetics; Gene expression; Endocrinology; Gene","score_opus":0.02529263369399152,"score_gpt":0.3012481139349718,"score_spread":0.27595548024098027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2610936921","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005548742,0.99490696,0.0009634795,0.0002915973,0.00024810564,0.000011510073,0.000075148506,0.00002530781,0.0029229822],"genre_scores_gemma":[0.001624353,0.9954769,0.0007231077,0.00019331362,0.000087275235,0.00001450166,0.00010047646,0.0000050444523,0.0017749676],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998529,0.000016057236,0.000019466093,0.000042362193,0.000054845226,0.000014463682],"domain_scores_gemma":[0.99981326,0.00006829371,0.00002792169,0.000009428088,0.000063155334,0.000018020619],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047787346,0.000907551,0.0011816139,0.00236667,0.00021054855,0.0009550142,0.0007881288,0.0008337796,0.0018238549],"category_scores_gemma":[0.0004029701,0.0003563608,0.00044499122,0.0020474868,0.0005256432,0.0010059826,0.00053155323,0.0014404476,0.0018459766],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008854591,0.000062364255,0.00037952614,0.011111045,0.00009091938,0.00028876297,0.00007905317,0.0006585764,0.026325595,0.0075125797,0.014306219,0.9390968],"study_design_scores_gemma":[0.000012543763,0.00010206798,0.0016452817,0.0014206639,0.00010946787,0.0010659163,0.00007372519,0.00017732248,0.008777049,0.002366086,0.9842142,0.000035765595],"about_ca_topic_score_codex":0.000715781,"about_ca_topic_score_gemma":0.0012585891,"teacher_disagreement_score":0.00236667,"about_ca_system_score_codex":0.0007715274,"about_ca_system_score_gemma":0.00080190436,"threshold_uncertainty_score":0.00610137},"labels":[],"label_agreement":null},{"id":"W2774455476","doi":"10.1186/s13578-017-0196-9","title":"Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes","year":2017,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University","funders":"National Natural Science Foundation of China; Harbin Medical University","keywords":"Cardioprotection; Endoplasmic reticulum; Apoptosis; Cell biology; Viability assay; Caspase 12; Mitochondrial permeability transition pore; Unfolded protein response; Chemistry; Cytochrome c; Oxidative stress; Biology; Caspase; Programmed cell death; Medicine; Ischemia; Internal medicine; Biochemistry","score_opus":0.013358059110180816,"score_gpt":0.25301532862507187,"score_spread":0.23965726951489105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2774455476","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99531025,0.0026677467,0.000974278,0.000084146035,0.00010022558,0.000023024131,0.00021748985,0.00006550607,0.00055738015],"genre_scores_gemma":[0.99502087,0.0018730757,0.0008394831,0.000115962954,0.000039750925,0.00002702832,0.0003866726,0.000014049119,0.0016831441],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999423,0.000008388709,0.0000106793605,0.000011255755,0.000010897432,0.000016511187],"domain_scores_gemma":[0.99993026,0.0000048590578,0.00002148401,0.000008341142,0.000009142102,0.000025931697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014501551,0.00034015585,0.0003844606,0.0001669943,0.00011632361,0.00017161982,0.00015053927,0.00021064273,0.0008812782],"category_scores_gemma":[0.000080670536,0.00015206911,0.0002597747,0.00008522192,0.00018405112,0.00023189482,0.0001595896,0.00044251894,0.00016432579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044345585,0.00006944182,0.00011463411,0.000060316972,0.000009490753,0.000050425613,0.000013417681,0.000050257386,0.9981199,0.000024743204,0.000044697717,0.0009991801],"study_design_scores_gemma":[0.00012593555,0.0033535403,0.013290174,0.00002189294,0.0000681455,0.00023869055,0.00006680094,0.00080349715,0.9792051,0.00008173663,0.002733914,0.000010467238],"about_ca_topic_score_codex":0.00039435073,"about_ca_topic_score_gemma":0.0007097844,"teacher_disagreement_score":0.0008812782,"about_ca_system_score_codex":0.0001273448,"about_ca_system_score_gemma":0.00018594382,"threshold_uncertainty_score":0.002948165},"labels":[],"label_agreement":null},{"id":"W2917939725","doi":"10.1186/s13578-017-0169-z","title":"The 2016 Ming K Jeang Award for Excellence in Cell & Bioscience","year":2017,"lang":"en","type":"editorial","venue":"Cell & Bioscience","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institutes of Health","keywords":"Excellence; Library science; Management; Political science; Computer science; Law","score_opus":0.041580140234038714,"score_gpt":0.3097925303009447,"score_spread":0.268212390066906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2917939725","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003714827,0.007468738,0.00016126859,0.029898124,0.959264,0.000019702675,0.000052325748,0.000058736674,0.0030399247],"genre_scores_gemma":[0.0006783387,0.01243356,0.000206995,0.021934962,0.9298641,0.000027569578,0.00006469624,0.000050490966,0.034739245],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974306,0.00030061707,0.00028161856,0.00026010137,0.0015580282,0.00016907905],"domain_scores_gemma":[0.9920889,0.0021229065,0.0005557044,0.00022946212,0.0033938526,0.0016090195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004738287,0.0030084949,0.0022740047,0.002355084,0.001952793,0.0061137923,0.0029600495,0.0102130305,0.015922507],"category_scores_gemma":[0.010704347,0.0009587375,0.0017391425,0.0010063133,0.0020304092,0.0036949518,0.001390695,0.020151636,0.015714686],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038949278,0.000009801054,0.000024395997,0.0001488888,0.000010244572,0.00009152326,0.000009150907,0.00002560336,0.0000853342,0.0006263902,0.99166685,0.007262991],"study_design_scores_gemma":[0.000040340663,0.000019197474,0.00015098181,0.00017617071,0.000020510559,0.00017253983,0.000024423369,0.00009109977,0.00011230979,0.0010191055,0.9981614,0.000011969785],"about_ca_topic_score_codex":0.0014608596,"about_ca_topic_score_gemma":0.0068607433,"teacher_disagreement_score":0.015922507,"about_ca_system_score_codex":0.0032267235,"about_ca_system_score_gemma":0.002983039,"threshold_uncertainty_score":0.053266108},"labels":[],"label_agreement":null},{"id":"W2941309557","doi":"10.1186/s13578-019-0272-4","title":"Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus","year":2019,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Scientific Research Foundation for Returned Scholars of Ministry of Education; Ministry of Education of the People's Republic of China; Nanchang University; Institute of Genetics; National Natural Science Foundation of China; Chinese Academy of Sciences; Case Western Reserve University","keywords":"Dentate gyrus; Neurogenesis; Hippocampal formation; DISC1; Hippocampus; AXIN2; Neuroscience; Wnt signaling pathway; Biology; Cell biology; Signal transduction; Genetics; Gene","score_opus":0.006081526080799598,"score_gpt":0.2043139161095846,"score_spread":0.198232390028785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2941309557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99536043,0.0017768566,0.0013374385,0.00012041217,0.000030510655,0.000009477755,0.00038648743,0.000064495405,0.0009138753],"genre_scores_gemma":[0.99481636,0.00095016276,0.0016260934,0.00006559463,0.000008083214,0.000018866369,0.0005550206,0.000013775827,0.0019460501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993455,0.000007721438,0.000006764678,0.000021825987,0.00001734559,0.000011669803],"domain_scores_gemma":[0.99993753,0.0000044058797,0.00003337805,0.0000039111515,0.00000610868,0.000014711737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005124993,0.00027127797,0.00015547956,0.0001773539,0.00012754774,0.00014565603,0.00009781124,0.0003130814,0.0010992519],"category_scores_gemma":[0.00008469531,0.00007783688,0.00019136177,0.000092047856,0.00019204356,0.00013859873,0.0001465524,0.00031194594,0.0002635085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012541335,0.000011092875,0.0011596002,0.000044012555,0.0000057758893,0.00039350806,0.000025323165,0.000028123128,0.996163,0.00012875344,0.00008212354,0.0018332333],"study_design_scores_gemma":[0.00006860356,0.0004975838,0.09025269,0.00005189587,0.00008837025,0.0056704134,0.0001998366,0.001187004,0.888923,0.00043018963,0.012616545,0.000013820887],"about_ca_topic_score_codex":0.00035736017,"about_ca_topic_score_gemma":0.0004550647,"teacher_disagreement_score":0.0010992519,"about_ca_system_score_codex":0.00016729711,"about_ca_system_score_gemma":0.00008069669,"threshold_uncertainty_score":0.0036773682},"labels":[],"label_agreement":null},{"id":"W2947588340","doi":"10.1186/s13578-019-0292-0","title":"Caspase-11, a specific sensor for intracellular lipopolysaccharide recognition, mediates the non-canonical inflammatory pathway of pyroptosis","year":2019,"lang":"en","type":"review","venue":"Cell & Bioscience","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"Applied Basic Research Key Project of Yunnan","keywords":"Pyroptosis; Cell biology; Caspase 1; Caspase; Lipopolysaccharide; Inflammation; Innate immune system; Programmed cell death; Biology; Chemistry; Inflammasome; Apoptosis; Immunology; Biochemistry; Immune system","score_opus":0.029388679327402252,"score_gpt":0.26318078083134844,"score_spread":0.2337921015039462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947588340","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034171678,0.996176,0.0006134057,0.00029800847,0.00027258112,0.000012738324,0.000039114962,0.000023643428,0.0022227105],"genre_scores_gemma":[0.0026093265,0.99503726,0.00046843567,0.00019130937,0.00013268975,0.00001610838,0.00007568645,0.0000024497044,0.0014667059],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99981433,0.000025174368,0.000025673506,0.00003697602,0.00007691163,0.000021037662],"domain_scores_gemma":[0.9998301,0.00004769669,0.000031545107,0.000006265723,0.00006154782,0.000022806948],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034350084,0.00092541444,0.00095972256,0.0019454058,0.00025204444,0.00081065646,0.0006338336,0.00083596964,0.0020188112],"category_scores_gemma":[0.00030602273,0.00020671201,0.0003410776,0.001705755,0.0005321281,0.00096687087,0.0005381515,0.001506769,0.0020023573],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012552817,0.000097628676,0.00039377352,0.010927765,0.00008790709,0.00036082312,0.00006371531,0.00039969946,0.0145169245,0.0074921893,0.023357973,0.94217604],"study_design_scores_gemma":[0.000026536321,0.00013960827,0.0011895641,0.0011201281,0.00006711439,0.0021660372,0.00006044724,0.00017249485,0.006308901,0.0028230695,0.98589814,0.000027929244],"about_ca_topic_score_codex":0.00048354638,"about_ca_topic_score_gemma":0.0007636754,"teacher_disagreement_score":0.0020188112,"about_ca_system_score_codex":0.0007748592,"about_ca_system_score_gemma":0.00092368963,"threshold_uncertainty_score":0.006753564},"labels":[],"label_agreement":null},{"id":"W2953738482","doi":"10.1186/s13578-019-0316-9","title":"Regulation of platelet-activating factor-mediated interleukin-6 promoter activation by the 48 kDa but not the 45 kDa isoform of protein tyrosine phosphatase non-receptor type 2","year":2019,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Gene isoform; Protein tyrosine phosphatase; Biology; Receptor tyrosine kinase; Receptor; Phosphatase; Cell biology; Molecular biology; Chemistry; Biochemistry; Phosphorylation; Gene","score_opus":0.008112143710875527,"score_gpt":0.22204600948489012,"score_spread":0.21393386577401458,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953738482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993167,0.0022252183,0.002623944,0.00008575042,0.000039107243,0.000027747774,0.0003564426,0.000032432203,0.001442517],"genre_scores_gemma":[0.9957195,0.00082598627,0.0014008193,0.0000440131,0.000013507131,0.000046488432,0.00057859486,0.0000107297965,0.0013603166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998197,0.000038105536,0.000012479788,0.0000425102,0.000040630264,0.00004659491],"domain_scores_gemma":[0.999905,0.000022221238,0.000031844997,0.000009635372,0.000012363925,0.000018946297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015917896,0.00029291198,0.00015702787,0.0001456823,0.00009607099,0.00025768657,0.000108485554,0.00015782811,0.0014199067],"category_scores_gemma":[0.00015585123,0.00011913248,0.0002447508,0.00009458466,0.00016349262,0.00016192625,0.00016605463,0.00034409788,0.00042567475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013866407,0.000025059026,0.00018841306,0.00003223294,0.000003223999,0.000027460868,0.000015144563,0.000035749246,0.9987153,0.00007887771,0.000031177482,0.000708644],"study_design_scores_gemma":[0.00004855478,0.00034918275,0.012342729,0.000011322462,0.000017946553,0.00038861405,0.000051832845,0.0030489883,0.9800034,0.00009476657,0.0036362836,0.0000062856698],"about_ca_topic_score_codex":0.00026202563,"about_ca_topic_score_gemma":0.00034563112,"teacher_disagreement_score":0.0014199067,"about_ca_system_score_codex":0.00025496996,"about_ca_system_score_gemma":0.00012132628,"threshold_uncertainty_score":0.004750073},"labels":[],"label_agreement":null},{"id":"W2999557082","doi":"10.1186/s13578-019-0367-y","title":"Enhanced efficiency in isolation and expansion of hAMSCs via dual enzyme digestion and micro-carrier","year":2020,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Science Foundation of Hunan Province; National Natural Science Foundation of China","keywords":"Collagenase; Subculture (biology); Stem cell; Chemistry; Chitosan; Digestion (alchemy); Cell culture; In vitro; Chromatography; Molecular biology; Enzyme; Biochemistry; Biology; Cell biology; Microbiology","score_opus":0.010237444944678634,"score_gpt":0.2313995303570108,"score_spread":0.22116208541233218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999557082","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9107737,0.004348517,0.07990245,0.00018361006,0.00018213411,0.00014777239,0.0006006664,0.00089916104,0.0029620857],"genre_scores_gemma":[0.9321976,0.0013299169,0.062281575,0.00009100838,0.000038343576,0.00010339052,0.00039278466,0.00008346494,0.0034819157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980766,0.000028416518,0.00001860163,0.000041433417,0.000075984855,0.000027884704],"domain_scores_gemma":[0.999863,0.000033092532,0.000030790292,0.00001734134,0.000031006606,0.000024813471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021360285,0.00040789883,0.0003071744,0.00028958378,0.00009748924,0.00031255055,0.00018794807,0.00031500356,0.00053899316],"category_scores_gemma":[0.00015777515,0.0001322702,0.00022345984,0.0001909535,0.00017020445,0.0001440589,0.00024078654,0.00030070636,0.00037733652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012048345,0.000006558535,0.00004654427,0.000014704641,0.0000014614781,0.00002925123,0.0000050399817,0.000037633614,0.9988217,0.00002377784,0.000023960605,0.0009774492],"study_design_scores_gemma":[0.0000028130376,0.00004202627,0.0006597014,0.0000023706232,0.0000081658245,0.00009073572,0.00000429874,0.0006783909,0.99746704,0.000009006013,0.0010319132,0.0000034622144],"about_ca_topic_score_codex":0.00067176134,"about_ca_topic_score_gemma":0.001365926,"teacher_disagreement_score":0.00067176134,"about_ca_system_score_codex":0.00020563748,"about_ca_system_score_gemma":0.00019570212,"threshold_uncertainty_score":0.0018031597},"labels":[],"label_agreement":null},{"id":"W3011251699","doi":"10.1186/s13578-020-00397-0","title":"Quercetin and cancer: new insights into its therapeutic effects on ovarian cancer cells","year":2020,"lang":"en","type":"review","venue":"Cell & Bioscience","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":295,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Ovarian cancer; Cancer; Quercetin; In vivo; Medicine; Malignancy; Cancer research; Pharmacology; Oncology; Bioinformatics; Biology; Internal medicine; Biotechnology","score_opus":0.020829595372184106,"score_gpt":0.2984045610513363,"score_spread":0.2775749656791522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011251699","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025331168,0.997858,0.00017568335,0.00041017157,0.0002112342,0.00000482871,0.00001632848,0.000007666517,0.0010626563],"genre_scores_gemma":[0.0014225749,0.99756795,0.00012995483,0.0001988799,0.00013889195,0.000004250705,0.00002496256,0.0000011367933,0.0005113424],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998896,0.000019485977,0.000011652065,0.000020704709,0.000043893357,0.000014602382],"domain_scores_gemma":[0.99987733,0.00004762122,0.000012891992,0.000004748732,0.000041618798,0.000015837215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004354585,0.0006837952,0.00069970015,0.0018201345,0.00027905207,0.0007484554,0.00058644084,0.00088122237,0.0026038925],"category_scores_gemma":[0.0003949297,0.00020481503,0.00045951872,0.0014570416,0.0004337677,0.0011132429,0.00061890564,0.0017227518,0.00097067025],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009204779,0.00008840812,0.00022357282,0.010834974,0.00007858277,0.0003093596,0.00010441499,0.00047850664,0.006279288,0.008286124,0.02491753,0.9483071],"study_design_scores_gemma":[0.00001959946,0.00013870723,0.000835782,0.0013455786,0.00007737821,0.0008168303,0.000047034056,0.00012595757,0.0011281227,0.0030809161,0.99236673,0.000017329054],"about_ca_topic_score_codex":0.0011249331,"about_ca_topic_score_gemma":0.0026012582,"teacher_disagreement_score":0.0026038925,"about_ca_system_score_codex":0.0006294559,"about_ca_system_score_gemma":0.00065441185,"threshold_uncertainty_score":0.008710861},"labels":[],"label_agreement":null},{"id":"W3098350592","doi":"10.1186/s13578-020-00496-y","title":"Enhancing the antibacterial activities of sow milk via site-specific knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology","year":2020,"lang":"en","type":"letter","venue":"Cell & Bioscience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Transgenic Science and Technology Program; National Swine Industry Technology System; Fundamental Research Funds for the Central Universities","keywords":"Lactoferrin; Colostrum; Biology; Casein; CRISPR; Lactation; Genetically modified organism; Gene; Food science; Immunology; Genetics; Antibody","score_opus":0.01088258537585482,"score_gpt":0.2579619568912109,"score_spread":0.24707937151535606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3098350592","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.964886,0.00082420907,0.030105626,0.00025111507,0.00013122484,0.00007114229,0.0005559972,0.0004575992,0.0027169227],"genre_scores_gemma":[0.9774097,0.0006746506,0.014441815,0.00012201911,0.00001723612,0.00008125683,0.0006370958,0.000073394316,0.0065427497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984264,0.00002434019,0.00001787828,0.000042214637,0.000042509273,0.000030314743],"domain_scores_gemma":[0.99987304,0.000021867689,0.000056438967,0.000013876307,0.000011972155,0.000022804752],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024914296,0.00035802068,0.00025107258,0.00019794796,0.0001304853,0.00032532043,0.00025968038,0.0005170602,0.0011760226],"category_scores_gemma":[0.00015197853,0.0001854157,0.00035297594,0.0000856204,0.00024247174,0.00017933789,0.0003095802,0.0005351415,0.00031397425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037186466,0.000013395134,0.00014595804,0.000032622604,0.0000047382864,0.00007990051,0.000011680803,0.000076104436,0.998248,0.00010238656,0.000033807715,0.0012143161],"study_design_scores_gemma":[0.000023006705,0.00028966734,0.0034014226,0.000012751966,0.000034551784,0.0003888703,0.000028011882,0.002191993,0.98818177,0.00008722477,0.0053483522,0.00001244258],"about_ca_topic_score_codex":0.00044764622,"about_ca_topic_score_gemma":0.000574084,"teacher_disagreement_score":0.0011760226,"about_ca_system_score_codex":0.00019151327,"about_ca_system_score_gemma":0.00021040306,"threshold_uncertainty_score":0.0039342046},"labels":[],"label_agreement":null},{"id":"W3118289382","doi":"10.1186/s13578-020-00527-8","title":"Extracellular vesicles in bone and periodontal regeneration: current and potential therapeutic applications","year":2021,"lang":"en","type":"review","venue":"Cell & Bioscience","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Hamadan University of Medical Sciences","keywords":"Mesenchymal stem cell; Regenerative medicine; Regeneration (biology); Stem cell; Extracellular vesicles; Tissue engineering; Cell biology; Medicine; Bioinformatics; Biomedical engineering; Biology","score_opus":0.019945749084728518,"score_gpt":0.2955090209064125,"score_spread":0.275563271821684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118289382","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018428048,0.9987562,0.00012599537,0.00012270482,0.000100659505,0.0000028804068,0.0000113397455,0.000004591986,0.00069142034],"genre_scores_gemma":[0.00082082476,0.99834096,0.00017489605,0.00007403828,0.00008459381,0.0000044166845,0.000017459517,0.0000011636042,0.00048166307],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998795,0.000018067898,0.00001796073,0.000023209552,0.00004791232,0.000013299455],"domain_scores_gemma":[0.99985945,0.00006584119,0.000021078053,0.000004670329,0.000032318923,0.000016646625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038056725,0.00060241873,0.0008531685,0.0019093206,0.00025863666,0.0009979137,0.00044484893,0.0009559952,0.0031632653],"category_scores_gemma":[0.00035144328,0.0002349953,0.00037746533,0.0020515146,0.00033916565,0.0013101146,0.0006603694,0.0010753829,0.001628724],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065377026,0.00007565426,0.00014416309,0.014163499,0.000048929513,0.00025043823,0.000095596,0.00032064275,0.005888592,0.0049173706,0.010928157,0.96310145],"study_design_scores_gemma":[0.000012120994,0.00012568748,0.00059583754,0.0029687956,0.00009613882,0.0015589246,0.000097294986,0.00014148848,0.001832666,0.0023582177,0.99018973,0.000023063854],"about_ca_topic_score_codex":0.0006195451,"about_ca_topic_score_gemma":0.0009563167,"teacher_disagreement_score":0.0031632653,"about_ca_system_score_codex":0.00033063215,"about_ca_system_score_gemma":0.00072704506,"threshold_uncertainty_score":0.010582209},"labels":[],"label_agreement":null},{"id":"W3128352770","doi":"10.1186/s13578-021-00532-5","title":"Integrin αIIbβ3 outside-in signaling activates human platelets through serine 24 phosphorylation of Disabled-2","year":2021,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; China Medical University; Ministry of Science and Technology, Taiwan; China Medical University Hospital; Chang Gung Medical Foundation; York University; Chang Gung Memorial Hospital","keywords":"Integrin; Phosphorylation; Cell biology; CD49c; Platelet activation; Integrin alpha M; Platelet; Signal transduction; Platelet Glycoprotein GPIIb-IIIa Complex; Integrin, beta 6; Chemistry; Protein phosphorylation; Biology; Biochemistry; Protein kinase A; Receptor; Immunology","score_opus":0.025367438027598475,"score_gpt":0.2886121157285396,"score_spread":0.2632446777009411,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128352770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956589,0.0006024657,0.0016154379,0.00007437451,0.000021059197,0.000021799064,0.00025081012,0.000026331252,0.0017289327],"genre_scores_gemma":[0.99713254,0.0003037654,0.00058678485,0.00004187917,0.000007741291,0.000019591902,0.00038449018,0.0000055415817,0.0015177355],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999138,0.0000141365,0.0000048468332,0.000014904317,0.00001712583,0.000035049692],"domain_scores_gemma":[0.9999721,0.000004610978,0.000008606394,0.0000037406633,0.0000023527762,0.000008621419],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006444043,0.00028831547,0.00012881892,0.00009853573,0.00012923169,0.00023400171,0.00009869324,0.00014430787,0.0023194873],"category_scores_gemma":[0.000069115966,0.00010239618,0.00021149943,0.00011038748,0.00007842047,0.00008688886,0.00013965378,0.00031297785,0.00043836742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015273927,0.00001659759,0.00016853862,0.000022548667,0.0000037946766,0.00009582457,0.000010208565,0.000026613736,0.99881566,0.00009876346,0.000055641456,0.0005330524],"study_design_scores_gemma":[0.000039992705,0.00021228028,0.007928674,0.000004631324,0.000016208998,0.0006214323,0.000030324993,0.00083130033,0.9870521,0.000079985744,0.0031789143,0.0000041436483],"about_ca_topic_score_codex":0.00034452885,"about_ca_topic_score_gemma":0.0003324914,"teacher_disagreement_score":0.0023194873,"about_ca_system_score_codex":0.0001871341,"about_ca_system_score_gemma":0.00010534234,"threshold_uncertainty_score":0.007759452},"labels":[],"label_agreement":null},{"id":"W3186286157","doi":"10.1186/s13578-021-00662-w","title":"Potential of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy","year":2021,"lang":"en","type":"review","venue":"Cell & Bioscience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Cystic Fibrosis Canada; Canadian Institutes of Health Research; Cystic Fibrosis Foundation Therapeutics","keywords":"CRISPR; Genetic enhancement; Cas9; Genome editing; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator; Biology; Viral vector; Computational biology; Gene; Genetics","score_opus":0.014071238350403196,"score_gpt":0.3261055839795827,"score_spread":0.31203434562917953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186286157","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06561383,0.69702023,0.19667822,0.0032729704,0.0022660114,0.0005994014,0.0006148286,0.0014645128,0.03247003],"genre_scores_gemma":[0.35747796,0.5131723,0.112237416,0.0013111606,0.00051852636,0.0004265729,0.0010926217,0.00017487527,0.013588578],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995345,0.000101901795,0.000051934734,0.00008659831,0.00016841866,0.0000567414],"domain_scores_gemma":[0.9998729,0.00005234436,0.000020929909,0.000008676988,0.000026714748,0.00001837684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007735124,0.0005319868,0.0005961597,0.0005911176,0.00025355883,0.0010994263,0.0005386829,0.0009399578,0.00092721486],"category_scores_gemma":[0.00039317898,0.00033820714,0.0006150541,0.0003474594,0.000486614,0.00075058104,0.0005228813,0.0014504312,0.00068048463],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033491265,0.00018608493,0.00095061696,0.0057149976,0.00011936281,0.0017827281,0.00039895173,0.003190503,0.57719105,0.025048025,0.006876908,0.37820584],"study_design_scores_gemma":[0.00008517612,0.0015519804,0.001560989,0.000682942,0.00027665077,0.0054089967,0.00015403352,0.0070304056,0.49738836,0.0058705453,0.47985047,0.00013932925],"about_ca_topic_score_codex":0.0006073169,"about_ca_topic_score_gemma":0.000602838,"teacher_disagreement_score":0.0010994263,"about_ca_system_score_codex":0.0004592593,"about_ca_system_score_gemma":0.0005065087,"threshold_uncertainty_score":0.004090786},"labels":[],"label_agreement":null},{"id":"W4200174260","doi":"10.1186/s13578-021-00712-3","title":"Soluble amyloid-beta isoforms predict downstream Alzheimer’s disease pathology","year":2021,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Douglas Mental Health University Institute; McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Instituto Serrapilheira; Alzheimer's Association","keywords":"Gene isoform; Neurodegeneration; Proteomics; Amyloid beta; Alzheimer's disease; Cerebrospinal fluid; Disease; Biology; Downregulation and upregulation; Amyloid (mycology); Biochemistry; Computational biology; Neuroscience; Pathology; Gene; Medicine; Peptide","score_opus":0.02886931531391346,"score_gpt":0.2972106478190271,"score_spread":0.26834133250511366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200174260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9831891,0.00037564104,0.015345826,0.00009502513,0.000012013797,0.000020561056,0.00040522192,0.00014916256,0.00040728075],"genre_scores_gemma":[0.9958937,0.00007231673,0.0033665174,0.000019035077,0.0000091555585,0.000011637152,0.0005024441,0.000007852449,0.00011725544],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99971193,0.000081183105,0.00002633818,0.000110456196,0.000039178594,0.000030816365],"domain_scores_gemma":[0.9988444,0.0006377079,0.00020260912,0.000095483774,0.00014467811,0.00007509446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017030711,0.00094615575,0.00042363166,0.0007294244,0.00024235738,0.0008338789,0.00036144943,0.0004703682,0.0010288757],"category_scores_gemma":[0.0027376164,0.00017487002,0.0009802034,0.00033794896,0.00024926863,0.00043153547,0.00048383523,0.00067730335,0.00037350712],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017762394,0.00052122626,0.73112035,0.00019440429,0.0009655994,0.00023056706,0.00015862625,0.1621236,0.029186996,0.00022122114,0.0008851036,0.07261605],"study_design_scores_gemma":[0.000029371293,0.0006189608,0.2365784,0.00004920507,0.00033371014,0.0003045663,0.00007914836,0.7532912,0.0070257047,0.0012579354,0.00040600167,0.00002575646],"about_ca_topic_score_codex":0.0021432962,"about_ca_topic_score_gemma":0.0019296098,"teacher_disagreement_score":0.0021432962,"about_ca_system_score_codex":0.00035005258,"about_ca_system_score_gemma":0.0004018532,"threshold_uncertainty_score":0.009006798},"labels":[],"label_agreement":null},{"id":"W4225699254","doi":"10.1186/s13578-021-00723-0","title":"Intranasal HD-Ad vaccine protects the upper and lower respiratory tracts of hACE2 mice against SARS-CoV-2","year":2021,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; McMaster University; Sunnybrook Health Science Centre; University of Waterloo; SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Nasal administration; Medicine; Immunization; Virology; Immunology; Immunity; Coronavirus disease 2019 (COVID-19); Respiratory system; Regimen; Transmission (telecommunications); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Respiratory tract; Pandemic; Antibody; Immune system; Disease; Internal medicine; Infectious disease (medical specialty)","score_opus":0.038119769552283675,"score_gpt":0.32133870223953354,"score_spread":0.28321893268724985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225699254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99290127,0.00064988027,0.0035772575,0.00023068255,0.00007381457,0.00008440154,0.0006853023,0.00014589369,0.0016514526],"genre_scores_gemma":[0.98305327,0.00071254245,0.0064020823,0.00021470194,0.000037456663,0.00014184925,0.0015894652,0.00004055558,0.007807921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998777,0.000012850385,0.000013490431,0.000031446463,0.000026878046,0.000037672504],"domain_scores_gemma":[0.9999225,0.000009062395,0.000020921088,0.000011634926,0.00000952353,0.000026315854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018564923,0.0005003876,0.0002218132,0.00027277754,0.00014024095,0.00017772378,0.00020029802,0.00038000464,0.0019134424],"category_scores_gemma":[0.000065040076,0.00013924012,0.0002242814,0.000073743926,0.0002464381,0.0002797481,0.000109201064,0.0011009848,0.00055143225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020512834,0.00022696586,0.00017448507,0.0000266755,0.0000033532888,0.00002594073,0.000013176886,0.00004937835,0.9980336,0.000078327575,0.0000685242,0.0010945274],"study_design_scores_gemma":[0.00009633213,0.0023148535,0.0029290468,0.000009345877,0.000015712385,0.00025750915,0.00002850833,0.00093740976,0.9908059,0.00005916704,0.0025422142,0.0000038518738],"about_ca_topic_score_codex":0.00028707733,"about_ca_topic_score_gemma":0.00038693423,"teacher_disagreement_score":0.0019134424,"about_ca_system_score_codex":0.00023370715,"about_ca_system_score_gemma":0.0002272673,"threshold_uncertainty_score":0.006401062},"labels":[],"label_agreement":null},{"id":"W4291291776","doi":"10.1186/s13578-022-00871-x","title":"OpenVar: functional annotation of variants in non-canonical open reading frames","year":2022,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"PROTEO; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs; Ministère de l'Économie, de la Science et de l'Innovation - Québec; Compute Canada; Université de Sherbrooke","keywords":"Annotation; Open reading frame; Reading (process); Computer science; Biology; Computational biology; Information retrieval; Artificial intelligence; Genetics; Linguistics","score_opus":0.01301291806527359,"score_gpt":0.25376484223986573,"score_spread":0.24075192417459212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291291776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46678826,0.010286822,0.21692313,0.0008138337,0.000978283,0.00054698513,0.2151044,0.07864661,0.009911697],"genre_scores_gemma":[0.46727014,0.0018046472,0.18349972,0.00049274333,0.00036781965,0.00052437553,0.3319025,0.010981102,0.00315704],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99752265,0.00040839348,0.00031027914,0.0010122233,0.0005230459,0.00022331098],"domain_scores_gemma":[0.9942812,0.0032524671,0.0009350802,0.00075672363,0.00044361805,0.000330987],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035161166,0.0018133802,0.0017154033,0.005310679,0.0013132679,0.0023300669,0.0017323161,0.0013107237,0.0077633485],"category_scores_gemma":[0.007548627,0.00064808724,0.0019752127,0.0037877094,0.00060658075,0.0014371921,0.0023896804,0.001210061,0.0038476523],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01078386,0.0007484865,0.27651617,0.008913118,0.0026586347,0.006821986,0.0027698374,0.010731375,0.25828907,0.013064517,0.10696334,0.30173966],"study_design_scores_gemma":[0.0009939957,0.0018190595,0.36297035,0.0018534474,0.0023517034,0.016858742,0.0019684157,0.088018395,0.134008,0.03125773,0.35684505,0.0010550453],"about_ca_topic_score_codex":0.0011803686,"about_ca_topic_score_gemma":0.002030015,"teacher_disagreement_score":0.0077633485,"about_ca_system_score_codex":0.0004782357,"about_ca_system_score_gemma":0.0008405361,"threshold_uncertainty_score":0.025970995},"labels":[],"label_agreement":null},{"id":"W4303446437","doi":"10.1186/s13578-022-00903-6","title":"Krüppel-like factor 7 deficiency causes autistic-like behavior in mice via regulating Clock gene","year":2022,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Plant Molecular Biology Research","field":"Agricultural and Biological Sciences","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Natural Science Foundation of China","keywords":"Krüppel; Neuroscience; Biology; Gene; Psychology; Cell biology; Genetics; Transcription factor","score_opus":0.02702179639646726,"score_gpt":0.24881532521192085,"score_spread":0.22179352881545358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4303446437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98968434,0.0006361492,0.0061568646,0.00018638768,0.000061081155,0.00005820034,0.0011914945,0.00052920124,0.0014962294],"genre_scores_gemma":[0.9846875,0.00068186224,0.0068361247,0.00013460747,0.000016591928,0.000116360716,0.0010833874,0.00014401446,0.00629949],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997607,0.0000380637,0.000037296842,0.000061782295,0.00006181448,0.00004035162],"domain_scores_gemma":[0.9997018,0.00003314967,0.00012185893,0.000019470448,0.0000148330155,0.00010882158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013183401,0.0007454065,0.00022593598,0.00087710965,0.00022289997,0.00020034805,0.00030460546,0.0004959511,0.0030158053],"category_scores_gemma":[0.0001515655,0.00033124548,0.00046505543,0.00015652872,0.0003828366,0.00018744357,0.00032452864,0.0007266655,0.0005543771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001248657,0.000040475883,0.00034697787,0.00003073797,0.000010585989,0.000214098,0.00001332967,0.00006260418,0.99833256,0.00011096755,0.000047262245,0.00066549715],"study_design_scores_gemma":[0.000119925775,0.000877448,0.0237476,0.000040048886,0.00010224022,0.0022128478,0.00012283954,0.0033520707,0.9646276,0.000422084,0.0043468988,0.00002841655],"about_ca_topic_score_codex":0.00080545095,"about_ca_topic_score_gemma":0.0015381193,"teacher_disagreement_score":0.0030158053,"about_ca_system_score_codex":0.00032769988,"about_ca_system_score_gemma":0.00021622838,"threshold_uncertainty_score":0.010088921},"labels":[],"label_agreement":null},{"id":"W4307841890","doi":"10.1186/s13578-022-00914-3","title":"Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake","year":2022,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; National Institutes of Health; Robert Wood Johnson Foundation Center for Health Policy; University of Toronto; Purdue University; Robert Wood Johnson Foundation","keywords":"Arcuate nucleus; Glucagon-like peptide-1; Nucleus; Receptor; Food intake; Endocrinology; Cell biology; Internal medicine; Glucagon-like peptide-2; Glucagon; Chemistry; Biology; Peptide; Neuroscience; Diabetes mellitus; Medicine; Biochemistry; Insulin; Type 2 diabetes","score_opus":0.03082638228772681,"score_gpt":0.24161224041052945,"score_spread":0.21078585812280265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307841890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99273646,0.0009755137,0.003564456,0.00014820052,0.000093414885,0.000028036899,0.00036379055,0.00022095293,0.0018692923],"genre_scores_gemma":[0.98845404,0.0008152789,0.0034201613,0.00015970638,0.000033913064,0.0001363966,0.00047965313,0.00009948497,0.006401444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982494,0.000017801303,0.000014054136,0.00004824915,0.00004187484,0.000053186446],"domain_scores_gemma":[0.9998461,0.00002607791,0.000037672427,0.000018009665,0.000017009112,0.000055051267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011518803,0.00032194625,0.00043885014,0.0002236973,0.00010164097,0.00027322522,0.00032575775,0.00028256833,0.002391641],"category_scores_gemma":[0.00015168145,0.00015864862,0.00031181454,0.00010193304,0.0003686979,0.00022473969,0.00020438372,0.0011079984,0.00051286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017383239,0.00003099466,0.00011307099,0.00004423028,0.000004867737,0.000026769263,0.000009877753,0.000032761687,0.9985946,0.000050533046,0.000042386582,0.00087604154],"study_design_scores_gemma":[0.00004261483,0.000583391,0.0050735753,0.000012585847,0.00002352232,0.00018755891,0.000056887624,0.0009493997,0.99103254,0.0000739899,0.0019587777,0.0000050874755],"about_ca_topic_score_codex":0.00037049715,"about_ca_topic_score_gemma":0.00058140827,"teacher_disagreement_score":0.002391641,"about_ca_system_score_codex":0.00026094538,"about_ca_system_score_gemma":0.0002332459,"threshold_uncertainty_score":0.008000791},"labels":[],"label_agreement":null},{"id":"W4313828796","doi":"10.1186/s13578-023-00954-3","title":"Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation","year":2023,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Planarian Biology and Electrostimulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Medical Research Council; Directorate for Biological Sciences; European Resuscitation Council; Chinese Academy of Sciences; University of Reading; Science, Technology and Innovation Commission of Shenzhen Municipality; National Natural Science Foundation of China","keywords":"Neural stem cell; Transplantation; Spinal cord injury; Neurogenesis; Stimulation; Spinal cord; Neuroscience; Stem cell; PI3K/AKT/mTOR pathway; Protein kinase B; Medicine; Biology; Cell biology; Internal medicine; Signal transduction","score_opus":0.020619217519462316,"score_gpt":0.27926230280923114,"score_spread":0.2586430852897688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313828796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888918,0.0036810925,0.0034913726,0.0001407419,0.000089968526,0.000045271387,0.00035007196,0.0001259787,0.0031837095],"genre_scores_gemma":[0.99422646,0.0018081557,0.0016416896,0.000056915567,0.000015249687,0.000055613506,0.00029238383,0.00000981137,0.0018937575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999956,0.0000030668,0.0000051683965,0.0000084277135,0.000015878919,0.000011538242],"domain_scores_gemma":[0.99998176,0.0000025611832,0.0000049815926,0.0000012416909,0.000004623876,0.0000048073507],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054513377,0.00022468163,0.00017878386,0.00019554619,0.00007553665,0.00014573564,0.00010471439,0.00016971197,0.0013860328],"category_scores_gemma":[0.00004668655,0.000053081963,0.00022081278,0.00012934684,0.00011522504,0.00014542774,0.00011155146,0.00035517832,0.00016496617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011073525,0.000044624117,0.00020581664,0.000117778734,0.000005989214,0.00006559727,0.000014658702,0.00012336527,0.99536985,0.000070107446,0.00010332711,0.0037682063],"study_design_scores_gemma":[0.000020967967,0.00044358402,0.0050878115,0.000016692986,0.000022953316,0.00017193658,0.000034495446,0.00087839446,0.99104226,0.00009559824,0.002180335,0.000005013544],"about_ca_topic_score_codex":0.00032087808,"about_ca_topic_score_gemma":0.00067700294,"teacher_disagreement_score":0.0013860328,"about_ca_system_score_codex":0.00012388999,"about_ca_system_score_gemma":0.000150246,"threshold_uncertainty_score":0.0046367645},"labels":[],"label_agreement":null},{"id":"W4317751876","doi":"10.1186/s13578-023-00966-z","title":"Identification of the molecular mechanism of insulin-like growth factor-1 (IGF-1): a promising therapeutic target for neurodegenerative diseases associated with metabolic syndrome","year":2023,"lang":"en","type":"review","venue":"Cell & Bioscience","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Research Foundation of Korea; Chonnam National University; National Research Foundation; Chonnam National University Hwasun Hospital; Mike and Josie Harper Cancer Research Institute","keywords":"Neurodegeneration; Metabolic syndrome; Medicine; Bioinformatics; Neurogenesis; Huntington's disease; Disease; Cognitive decline; Neuroscience; Biology; Diabetes mellitus; Internal medicine; Endocrinology; Dementia","score_opus":0.03791747422555943,"score_gpt":0.28646334069323465,"score_spread":0.2485458664676752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317751876","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016126448,0.9983078,0.00016206449,0.00030152057,0.00022954101,0.000003784419,0.000016396023,0.000005959811,0.00081158895],"genre_scores_gemma":[0.0010811063,0.9976751,0.0002592695,0.00020958913,0.00015135451,0.0000072025414,0.00002972915,0.0000012754823,0.0005852962],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99991024,0.00001468585,0.000012635509,0.000016903698,0.00003479864,0.000010727985],"domain_scores_gemma":[0.99987614,0.000051152503,0.000016812173,0.0000039309643,0.00003927216,0.000012785553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033114504,0.0006853,0.00082962355,0.0014947562,0.00021132648,0.00071972294,0.00051218027,0.00086928747,0.002861282],"category_scores_gemma":[0.00038463698,0.00016175419,0.00040378148,0.0011671942,0.00031835202,0.00090228027,0.00047638576,0.0016909431,0.0011900692],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014260337,0.00009702527,0.00024684457,0.016691448,0.00012825157,0.00034017768,0.00006059221,0.00035703307,0.0059258575,0.0059748585,0.026987161,0.9430481],"study_design_scores_gemma":[0.000034774464,0.00017451505,0.0010578334,0.0029736105,0.00018270698,0.0018309884,0.00006960961,0.0001839704,0.0019275356,0.0027821893,0.98875797,0.00002424012],"about_ca_topic_score_codex":0.00074621243,"about_ca_topic_score_gemma":0.0013340197,"teacher_disagreement_score":0.002861282,"about_ca_system_score_codex":0.0004339915,"about_ca_system_score_gemma":0.0007721301,"threshold_uncertainty_score":0.0095719695},"labels":[],"label_agreement":null},{"id":"W4364375960","doi":"10.1186/s13578-023-01015-5","title":"Improving the response to oxaliplatin by targeting chemotherapy-induced CLDN1 in resistant metastatic colorectal cancer cells","year":2023,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Conseil Régional du Centre-Val de Loire; Institute of Cancer Research; Institut National Du Cancer; European Regional Development Fund; Direction Générale de l’offre de Soins; Université d'Orléans; Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Oxaliplatin; Colorectal cancer; Apoptosis; Chemotherapy; Wnt signaling pathway; Cancer research; Flow cytometry; Cancer; Biology; Medicine; Internal medicine; Molecular biology; Cell biology; Signal transduction","score_opus":0.023375308935080268,"score_gpt":0.27304056149020195,"score_spread":0.24966525255512168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4364375960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99723583,0.0011416366,0.0009806473,0.00004776309,0.000011328857,0.000032270666,0.00014695703,0.000026536416,0.00037714108],"genre_scores_gemma":[0.99697435,0.0007383701,0.0012285591,0.000023675175,0.0000034284244,0.000029223038,0.0002757358,0.000006989411,0.00071966863],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991095,0.000012336792,0.000010605263,0.000021037085,0.000027270864,0.000017762912],"domain_scores_gemma":[0.99993086,0.000010301396,0.000022919165,0.000010281393,0.000011760794,0.000013867002],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015692684,0.00020352747,0.00029671425,0.00014829719,0.00012389472,0.00025359387,0.0001401447,0.00016958077,0.0008105086],"category_scores_gemma":[0.000113588336,0.00009109953,0.00016466207,0.00014528817,0.00011425849,0.00014862178,0.00014023452,0.00035178874,0.00016944823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009195943,0.00003923213,0.0004812782,0.00005382183,0.0000045548863,0.000019918161,0.000014266017,0.00010594908,0.99758327,0.000027278853,0.00003709765,0.0015414031],"study_design_scores_gemma":[0.00003874704,0.0009569662,0.009023213,0.000007410562,0.000026608821,0.00028719145,0.00003381408,0.001157938,0.9854778,0.000018259447,0.0029678682,0.0000040419563],"about_ca_topic_score_codex":0.00044068272,"about_ca_topic_score_gemma":0.00072090747,"teacher_disagreement_score":0.0008105086,"about_ca_system_score_codex":0.00032491874,"about_ca_system_score_gemma":0.00016388421,"threshold_uncertainty_score":0.0027114153},"labels":[],"label_agreement":null},{"id":"W4376134070","doi":"10.1186/s13578-023-01024-4","title":"ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1","year":2023,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Science and Technology Service Network Plan; Jiangsu Provincial Key Research and Development Program; Key Technologies Research and Development Program of Anhui Province","keywords":"Fertility; Ovulation; ISG15; Gynecology; Biology; Andrology; Demography; Medicine; Pregnancy; Population; Sociology; Genetics","score_opus":0.015078742574074856,"score_gpt":0.25097753743433493,"score_spread":0.23589879486026008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376134070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99388134,0.0015074266,0.00209517,0.00021277239,0.00007587747,0.00002572071,0.00024144001,0.00010241451,0.0018578923],"genre_scores_gemma":[0.9964142,0.000393152,0.00088930654,0.0000659765,0.000010287815,0.000016199258,0.00019500282,0.0000135071605,0.0020022788],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998099,0.000037264155,0.000020398986,0.00003420347,0.000047830097,0.00005041181],"domain_scores_gemma":[0.9998665,0.000009223678,0.000053615127,0.000018459612,0.000008575631,0.000043592863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017436569,0.00031515583,0.0002145972,0.0003130065,0.00013840657,0.00024657795,0.00023809931,0.00026733955,0.0019803047],"category_scores_gemma":[0.00010039364,0.000111933674,0.00031783586,0.00016087099,0.00041784902,0.00014636246,0.00020709728,0.00047454864,0.0002500642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002546385,0.000043549346,0.00089327723,0.000046254434,0.000016191712,0.0000753135,0.000013156138,0.000085031446,0.9960944,0.00025738688,0.00009956658,0.0021213167],"study_design_scores_gemma":[0.000029348841,0.00044918674,0.008026494,0.000008111698,0.0000280008,0.00022521162,0.000030870135,0.00061973586,0.98706764,0.00010024489,0.0034116856,0.000003504845],"about_ca_topic_score_codex":0.00032757304,"about_ca_topic_score_gemma":0.0005585268,"teacher_disagreement_score":0.0019803047,"about_ca_system_score_codex":0.0003078129,"about_ca_system_score_gemma":0.00021715586,"threshold_uncertainty_score":0.0066247582},"labels":[],"label_agreement":null},{"id":"W4382502181","doi":"10.1186/s13578-023-01033-3","title":"Spatiotemporal control of genome engineering in cone photoreceptors","year":2023,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Alcon Research Institute; Ministry of Science and Technology, Taiwan; National Eye Institute; Foundation Fighting Blindness; National Institutes of Health; Kaohsiung Medical University Chung-Ho Memorial Hospital; Kaohsiung Medical University; Sun Yat-sen University; Irving Medical Center, Columbia University; Research to Prevent Blindness; Eberhard Karls Universität Tübingen; National Cancer Institute; National Sun Yat-sen University","keywords":"Cre recombinase; Visual phototransduction; Biology; Retina; Opsin; Retinal; Achromatopsia; Cell biology; Transducin; Genetics; Computational biology; Neuroscience; Transgene; Gene; Genetically modified mouse; Biochemistry; Rhodopsin","score_opus":0.004959078648392408,"score_gpt":0.1985239937350749,"score_spread":0.1935649150866825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382502181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.902565,0.0017111498,0.08894793,0.00013859276,0.000091361515,0.00027927602,0.00084371946,0.0006553633,0.0047676177],"genre_scores_gemma":[0.9592237,0.0009815032,0.033059083,0.0000680321,0.000013029107,0.0001351314,0.0006575075,0.0002669818,0.0055949916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99976593,0.00003199987,0.000024870571,0.00005889675,0.000081045146,0.0000372553],"domain_scores_gemma":[0.9998387,0.0000321682,0.00005980161,0.000022518034,0.000020566784,0.000026114105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024015282,0.00035304087,0.00015807044,0.00025129577,0.00014303492,0.00040445948,0.0003145669,0.00035585326,0.000814627],"category_scores_gemma":[0.00016402116,0.00019877958,0.00029428944,0.0001236964,0.00021039242,0.0001619902,0.0003112962,0.0004792963,0.00031726973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011478272,0.000008359729,0.000030261184,0.000012156782,0.0000013382302,0.0000151012055,0.000007657985,0.00010305502,0.9989618,0.00015177591,0.000015512178,0.00068157347],"study_design_scores_gemma":[0.000009331879,0.000094209805,0.0005589239,0.000004168827,0.000007369384,0.00009895283,0.000009952137,0.0012234155,0.99442226,0.000052980784,0.0035143155,0.000004141209],"about_ca_topic_score_codex":0.0006719035,"about_ca_topic_score_gemma":0.00094077707,"teacher_disagreement_score":0.000814627,"about_ca_system_score_codex":0.00037515597,"about_ca_system_score_gemma":0.00024456324,"threshold_uncertainty_score":0.002725184},"labels":[],"label_agreement":null},{"id":"W4388424213","doi":"10.1186/s13578-023-01149-6","title":"METTL3-mediated m6A methylation regulates ovarian cancer progression by recruiting myeloid-derived suppressor cells","year":2023,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Immune system; Biology; Chemokine; Tumor microenvironment; Cancer research; Myeloid; Ovarian cancer; Secretion; Myeloid-derived Suppressor Cell; Immunology; Cell biology; Cancer; Endocrinology","score_opus":0.018464220066006606,"score_gpt":0.2902580532251721,"score_spread":0.2717938331591655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388424213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99106884,0.0032671723,0.0028095306,0.00019783028,0.000037797603,0.000039051167,0.0009096704,0.0001422831,0.0015279043],"genre_scores_gemma":[0.9964896,0.00068520673,0.0007567843,0.000050920215,0.000007944534,0.00003059104,0.0005526802,0.000015219061,0.001411136],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988556,0.00001238495,0.000010421022,0.000025711377,0.000026137903,0.000039837792],"domain_scores_gemma":[0.99990356,0.0000064388996,0.0000439771,0.000007144702,0.00001048972,0.000028316494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012709163,0.00020864622,0.00015905836,0.00022687501,0.00016765961,0.0002517075,0.00013466609,0.00022684473,0.0018720814],"category_scores_gemma":[0.0001082037,0.0001009384,0.0002846197,0.00013442399,0.00021307742,0.000118419615,0.00025575148,0.0003724784,0.00038279296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051073835,0.000032094118,0.0041793166,0.00011366781,0.000012530467,0.0001187294,0.00004217759,0.0000988609,0.99077344,0.00018490285,0.00019495655,0.0037386313],"study_design_scores_gemma":[0.000115992596,0.0006947586,0.055303887,0.000040283103,0.00007574665,0.0010308045,0.00019226133,0.0020680865,0.92546374,0.00027296282,0.014727965,0.000013473526],"about_ca_topic_score_codex":0.00048424886,"about_ca_topic_score_gemma":0.0008836885,"teacher_disagreement_score":0.0018720814,"about_ca_system_score_codex":0.0002806029,"about_ca_system_score_gemma":0.00025772958,"threshold_uncertainty_score":0.0062627792},"labels":[],"label_agreement":null},{"id":"W4391066065","doi":"10.1186/s13578-024-01193-w","title":"Rasal1 regulates calcium dependent neuronal maturation by modifying microtubule dynamics","year":2024,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Institute of Neurosciences, Mental Health and Addiction; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cell biology; Neurite; Calcium in biology; Intracellular; Biology; Neuroscience; Microtubule; Chemistry; Biochemistry; In vitro","score_opus":0.037773467691139824,"score_gpt":0.3206683034687089,"score_spread":0.2828948357775691,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391066065","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98842037,0.0023699189,0.0032147397,0.00025361002,0.000036182482,0.000030205627,0.00050334557,0.00022044657,0.0049511613],"genre_scores_gemma":[0.9926277,0.0013942587,0.001958873,0.000029677669,0.000014272102,0.00002775861,0.00031555866,0.000025400564,0.0036064868],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999194,0.0000074222376,0.0000041120848,0.000018227029,0.000023010578,0.000027827724],"domain_scores_gemma":[0.9999124,0.000009821589,0.000028530996,0.0000074250734,0.000017934706,0.000024038296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000064070635,0.00031413115,0.00010049796,0.00020422456,0.00031370498,0.00033797734,0.0002769806,0.00024521092,0.0019079845],"category_scores_gemma":[0.00009408666,0.00009859588,0.00018297342,0.0001002122,0.00019871078,0.00020656797,0.0001736789,0.0004307412,0.0006640323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081124614,0.00001779052,0.00029481293,0.00003557488,0.0000029893167,0.00006962946,0.000012535184,0.00006805613,0.99714786,0.00027279343,0.000082193284,0.0019147444],"study_design_scores_gemma":[0.000011420744,0.00010060751,0.008072107,0.000008702318,0.00001263332,0.00019725328,0.00003439789,0.0014069034,0.98536265,0.00015672667,0.0046321205,0.0000044459935],"about_ca_topic_score_codex":0.0006951059,"about_ca_topic_score_gemma":0.001501998,"teacher_disagreement_score":0.0019079845,"about_ca_system_score_codex":0.0005955682,"about_ca_system_score_gemma":0.00025871312,"threshold_uncertainty_score":0.006382823},"labels":[],"label_agreement":null},{"id":"W4391521883","doi":"10.1186/s13578-024-01199-4","title":"Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments","year":2024,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; University of British Columbia; McGill University; Jewish General Hospital","funders":"Leukemia and Lymphoma Society of Canada; Canadian Cancer Society; Fonds de Recherche du Québec - Santé; Cole Foundation; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Melanoma; Tumor microenvironment; Immune system; Tumour heterogeneity; Cell; Cancer research; Computational biology; Biology; Cancer; Medicine; Immunology","score_opus":0.009982558119830419,"score_gpt":0.25112225065370325,"score_spread":0.24113969253387282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391521883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9054024,0.0016598916,0.085148625,0.00020629501,0.000041569197,0.000091546346,0.0016846263,0.0010035892,0.00476146],"genre_scores_gemma":[0.9072217,0.0014140804,0.084033206,0.00020802066,0.000021615042,0.00019522138,0.0014894274,0.00026143645,0.00515539],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984086,0.000020543579,0.000007740798,0.000049329545,0.000049313127,0.000032096195],"domain_scores_gemma":[0.9998149,0.000048993843,0.000052387717,0.000028061937,0.000029749417,0.000025856012],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003662523,0.00025324666,0.00013654864,0.000393542,0.00013398287,0.0003087649,0.00021557357,0.00036049003,0.0014428721],"category_scores_gemma":[0.00015417597,0.00014458735,0.00014689082,0.00017097463,0.0002605705,0.00023621798,0.00020317614,0.00050627266,0.00036882394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025030557,0.000006460411,0.00021378911,0.000021187256,0.0000016897003,0.000022583397,0.000013200584,0.00013071159,0.9985935,0.00008731434,0.00005360496,0.0008309505],"study_design_scores_gemma":[0.000002888964,0.00006260164,0.0031168738,0.0000054744432,0.000007235298,0.0001348853,0.000021071477,0.001398821,0.99346536,0.00007009539,0.0017103559,0.0000044122244],"about_ca_topic_score_codex":0.00031393775,"about_ca_topic_score_gemma":0.000799688,"teacher_disagreement_score":0.0014428721,"about_ca_system_score_codex":0.0002883809,"about_ca_system_score_gemma":0.00017134087,"threshold_uncertainty_score":0.0048269033},"labels":[],"label_agreement":null},{"id":"W4400610744","doi":"10.1186/s13578-024-01273-x","title":"SUMOylation of nuclear receptor Nor1/NR4A3 coordinates microtubule cytoskeletal dynamics and stability in neuronal cells","year":2024,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Fertility Centre; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"SUMO protein; Microtubule; Cell biology; Cytoskeleton; Dynamics (music); Stem cell; Nuclear receptor; Microtubule-associated protein; Biology; Chemistry; Neuroscience; Physics; Transcription factor; Genetics; Ubiquitin; Cell; Gene","score_opus":0.012469321979339068,"score_gpt":0.22153681063343297,"score_spread":0.2090674886540939,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400610744","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99474686,0.00086762226,0.0021767481,0.000071694165,0.000022859696,0.0000102955,0.0006542215,0.00006849238,0.0013811283],"genre_scores_gemma":[0.9951565,0.00051802106,0.0011916751,0.000021716185,0.00000379508,0.00001543821,0.0006591576,0.000019115201,0.002414613],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998982,0.000008667829,0.000007992232,0.000028682165,0.00003118406,0.000025237225],"domain_scores_gemma":[0.99992657,0.000005323552,0.000025161422,0.00000921528,0.000014995641,0.00001872088],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008571238,0.00023807069,0.00018448861,0.00012304937,0.00020899346,0.00030077316,0.0002514885,0.00016051458,0.0011007217],"category_scores_gemma":[0.00007864686,0.000099328936,0.00024844462,0.00013186934,0.0001911025,0.00017874125,0.00019369478,0.00037224483,0.0004341266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008207749,0.0000070322494,0.00034519366,0.00001948396,0.0000037054665,0.000023043987,0.000009803842,0.00004859147,0.99884075,0.00006563319,0.000029734263,0.000525057],"study_design_scores_gemma":[0.000006313379,0.000050795094,0.0075301314,0.0000032085275,0.000009819704,0.0001172839,0.000036510664,0.0010726143,0.98962283,0.00003401108,0.0015131505,0.0000033813778],"about_ca_topic_score_codex":0.0017304197,"about_ca_topic_score_gemma":0.002742851,"teacher_disagreement_score":0.0017304197,"about_ca_system_score_codex":0.0006653281,"about_ca_system_score_gemma":0.00026647153,"threshold_uncertainty_score":0.004827261},"labels":[],"label_agreement":null},{"id":"W4400772439","doi":"10.1186/s13578-024-01276-8","title":"Integrative analysis of bulk and single-cell RNA sequencing reveals the gene expression profile and the critical signaling pathways of type II CPAM","year":2024,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Congenital Diaphragmatic Hernia Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Science Foundation of Zhejiang Province","keywords":"Biology; Gene; Cell type; Cell biology; RNA; Gene expression; Cell; Cilium; Computational biology; Genetics","score_opus":0.0334741078142353,"score_gpt":0.2782796007957447,"score_spread":0.24480549298150941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400772439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9210118,0.0030523227,0.052272677,0.00021278094,0.00009679884,0.000120306446,0.019440304,0.0006592108,0.00313371],"genre_scores_gemma":[0.89685446,0.0020911545,0.064476684,0.0004259172,0.00005359505,0.00048595227,0.031151166,0.00040607093,0.0040550306],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9996617,0.000024035042,0.000014998104,0.00015998328,0.00009346572,0.00004589914],"domain_scores_gemma":[0.9997781,0.00008150951,0.000045813387,0.00002211108,0.000047302925,0.00002523518],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033956472,0.000342207,0.000497023,0.00064678834,0.0003783716,0.0005553823,0.00023422134,0.00029830923,0.0011318992],"category_scores_gemma":[0.0004277517,0.0001720422,0.00062092807,0.0006388632,0.0002602636,0.00019617405,0.00039719342,0.00047582417,0.00039569396],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003075849,0.000041779374,0.015773509,0.0004477259,0.00011396869,0.0002617846,0.00019819669,0.0017988787,0.9555337,0.0005281327,0.00092316093,0.024071576],"study_design_scores_gemma":[0.00007488192,0.00063511444,0.45679256,0.00018643514,0.00056299317,0.0016619342,0.00087189686,0.07439408,0.4295038,0.002654591,0.03254651,0.000115152805],"about_ca_topic_score_codex":0.0013012915,"about_ca_topic_score_gemma":0.003318276,"teacher_disagreement_score":0.0013012915,"about_ca_system_score_codex":0.0002557503,"about_ca_system_score_gemma":0.00046943023,"threshold_uncertainty_score":0.0037865639},"labels":[],"label_agreement":null},{"id":"W4400867185","doi":"10.1186/s13578-024-01278-6","title":"Clostridium butyricum regulates intestinal barrier function via trek1 to improve behavioral abnormalities in mice with autism spectrum disorder","year":2024,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Key Scientific Research Project of Colleges and Universities in Henan Province; Natural Science Foundation of Henan Province","keywords":"Clostridium butyricum; Autism spectrum disorder; Gut–brain axis; Gut flora; Autism; Neurodevelopmental disorder; Neuroscience; HDAC1; Biology; Medicine; Immunology; Histone; Histone deacetylase; Biochemistry; Gene","score_opus":0.005086344338684479,"score_gpt":0.23145317364462084,"score_spread":0.22636682930593635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400867185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98950243,0.0034311893,0.0029976883,0.00077369733,0.00019556546,0.00009483154,0.00150492,0.00040344938,0.001096125],"genre_scores_gemma":[0.9892526,0.0021024882,0.0034153205,0.0003205881,0.00002074385,0.00022844547,0.0009356569,0.00009026276,0.0036338218],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997311,0.00003459402,0.000029057448,0.00006125715,0.000054318207,0.00008961351],"domain_scores_gemma":[0.99974626,0.0000125616425,0.00009163483,0.000017257786,0.00002773879,0.00010454282],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025059236,0.0007912665,0.00058288913,0.0005281828,0.00027622085,0.00031204856,0.00041008863,0.0006393949,0.0022681842],"category_scores_gemma":[0.00022711634,0.00021237544,0.000577623,0.000202914,0.00038743162,0.0003400628,0.00038498454,0.0014785342,0.0004454763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012312235,0.00017496276,0.0003554464,0.00013664074,0.000020391519,0.00007815043,0.000020588213,0.00008600597,0.99529785,0.000064780754,0.00013083777,0.002403163],"study_design_scores_gemma":[0.000525877,0.0050140526,0.015776271,0.000093012255,0.00020550867,0.00053096673,0.00025407932,0.0017321691,0.96981436,0.0002770696,0.0057409937,0.00003553275],"about_ca_topic_score_codex":0.0012937568,"about_ca_topic_score_gemma":0.0018654268,"teacher_disagreement_score":0.0022681842,"about_ca_system_score_codex":0.0005087112,"about_ca_system_score_gemma":0.00046671345,"threshold_uncertainty_score":0.00758785},"labels":[],"label_agreement":null},{"id":"W4412151545","doi":"10.1186/s13578-025-01436-4","title":"The role of m6A RNA methylation in a love-hate relationship between porcine rotavirus and host cells","year":2025,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Fundamental Research Funds for the Central Universities; National Key Research and Development Program of China; Jiangsu Provincial Key Research and Development Program; National Natural Science Foundation of China; Jiangsu Agricultural Science and Technology Innovation Fund","keywords":"Host (biology); Rotavirus; Methylation; RNA; Biology; Virology; Cell biology; Genetics; Computational biology; Virus; Gene","score_opus":0.010608728251613072,"score_gpt":0.26142640331826333,"score_spread":0.25081767506665026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412151545","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9758813,0.009432626,0.008445688,0.0004005388,0.00013749929,0.000041479016,0.00036719016,0.00016132579,0.0051323464],"genre_scores_gemma":[0.9954892,0.0008882899,0.0011645773,0.000121206176,0.000019662479,0.000019586549,0.00019835611,0.000010292694,0.0020888224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998221,0.000037116562,0.000009208072,0.000054818225,0.00002673666,0.000050113365],"domain_scores_gemma":[0.9998816,0.000012277241,0.00003463614,0.000017037348,0.000021023274,0.000033364122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002038341,0.00021928226,0.00024942888,0.00013509154,0.000305811,0.00041469524,0.00019062223,0.0004206181,0.001354312],"category_scores_gemma":[0.00019224345,0.00017147946,0.00031724948,0.00007520438,0.00029349173,0.00042873167,0.00054313097,0.0004521643,0.0003468797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016452443,0.000017056705,0.003465888,0.00007161806,0.000018856317,0.00021288241,0.00014510384,0.000072215225,0.9917549,0.00046163582,0.00012128309,0.0034940292],"study_design_scores_gemma":[0.000037439255,0.0011735596,0.13336068,0.000046775243,0.00007093754,0.0015552987,0.0009935607,0.003376689,0.8406997,0.0011086747,0.017527023,0.000049594317],"about_ca_topic_score_codex":0.00038322457,"about_ca_topic_score_gemma":0.00048428462,"teacher_disagreement_score":0.001354312,"about_ca_system_score_codex":0.00024992976,"about_ca_system_score_gemma":0.0001645646,"threshold_uncertainty_score":0.0045306087},"labels":[],"label_agreement":null}]}