{"meta":{"query_hash":"d6b1b7949093","filters":{"venue":"Cell Death and Disease"},"cohort_total":358,"direct_labels_cover":0,"predictions_cover":358,"exported":358,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/d6b1b7949093","api":"https://metacan.xera.ac/api/v1/cohort?venue=Cell+Death+and+Disease"},"results":[{"id":"W1097154589","doi":"10.1038/cddis.2015.209","title":"Hexokinase 2 controls cellular stress response through localization of an RNA-binding protein","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of British Columbia; Children's Hospital of Eastern Ontario","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cell biology; Gene knockdown; Stress granule; Heterogeneous ribonucleoprotein particle; RNA interference; Ribonucleoprotein; Biology; Cellular stress response; RNA-binding protein; Cytoplasm; Heterogeneous nuclear ribonucleoprotein; RNA; Molecular biology; Translation (biology); Apoptosis; Messenger RNA; Biochemistry; Fight-or-flight response; Gene","score_opus":0.017388058865755285,"score_gpt":0.2412445174668588,"score_spread":0.2238564586011035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1097154589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926448,0.002306004,0.0028944921,0.000055499168,0.0005624234,0.00033874277,0.000032393007,0.00004687367,0.0011187767],"genre_scores_gemma":[0.99149054,0.00001552438,0.00003453423,0.00011841104,0.000021948326,0.000023686785,0.00036931096,0.000013618719,0.007912428],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896735,0.00034717604,0.00023014893,0.00022548113,0.000044237633,0.00018561163],"domain_scores_gemma":[0.99935734,0.000040376748,0.0001242483,0.00023056802,0.00011394997,0.00013349949],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021183594,0.0001362864,0.00016821995,0.00006972975,0.000116096184,0.00002148181,0.00007358867,0.000105293075,0.00022015146],"category_scores_gemma":[0.00021852364,0.00012346989,0.00005116067,0.00006693079,0.00008279326,0.0002711203,0.000030886917,0.00010536348,0.00009198741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012207629,0.0005130373,0.0013344911,0.000073508934,0.000029156678,0.000026992955,0.0004885407,0.00007975859,0.9828482,0.0004573657,0.0015770447,0.0003642272],"study_design_scores_gemma":[0.0042948546,0.0006371855,0.00036801628,0.00007032863,0.00009573071,0.000004972478,0.0011660804,0.00044619697,0.9655111,0.00034468086,0.02682686,0.00023400928],"about_ca_topic_score_codex":0.00006281553,"about_ca_topic_score_gemma":0.000001087011,"teacher_disagreement_score":0.025249815,"about_ca_system_score_codex":0.00002964399,"about_ca_system_score_gemma":0.000121707104,"threshold_uncertainty_score":0.5034956},"labels":[],"label_agreement":null},{"id":"W1483418607","doi":"10.1038/cddis.2015.145","title":"Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Lady Davis Institute for Medical Research; Associazione Italiana per la Ricerca sul Cancro; Jewish General Hospital; Institut Català de Nanociència i Nanotecnologia","keywords":"Lytic cycle; Biology; BZLF1; Telomerase reverse transcriptase; Telomerase; Notch signaling pathway; Gene silencing; Cell biology; Epstein–Barr virus; Telomere; Transcription factor; Cancer research; Signal transduction; Virology; Virus; Genetics; Herpesviridae; Gene","score_opus":0.017069612995535412,"score_gpt":0.25945495561727944,"score_spread":0.24238534262174402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1483418607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99160147,0.0072562583,0.0000027608558,0.0003299413,0.000023086897,0.0003366876,0.00007640819,0.000004886134,0.00036850365],"genre_scores_gemma":[0.9993429,0.0002842301,0.00001663576,0.00020030724,0.00003838326,0.000006912753,0.0000064822793,0.000009232026,0.000094904266],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99906904,0.00006588018,0.00026355791,0.00017795358,0.00025438238,0.00016921396],"domain_scores_gemma":[0.99907786,0.00013665075,0.000106352454,0.00036062457,0.000062217405,0.0002562859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002643734,0.00012662775,0.0002576405,0.00004339195,0.00006232363,0.00001615515,0.0001391552,0.000045620356,0.0000076130486],"category_scores_gemma":[0.00012140153,0.000061946936,0.00005142254,0.00015140975,0.00035459088,0.000053121108,0.00008500845,0.00011017629,6.290231e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002701729,0.0001443919,0.98753166,0.00023948247,0.000016908443,0.00001256874,0.0014822368,0.0000030315136,0.0049872957,0.000046411067,0.000032701453,0.005233159],"study_design_scores_gemma":[0.0014824223,0.00009503662,0.9861677,0.00008923365,0.0001773193,0.0000067842593,0.0006633562,0.00019551306,0.009616671,0.0009766141,0.0004508286,0.00007846927],"about_ca_topic_score_codex":0.0006104426,"about_ca_topic_score_gemma":0.00002508961,"teacher_disagreement_score":0.007741445,"about_ca_system_score_codex":0.0000071522927,"about_ca_system_score_gemma":0.000118237804,"threshold_uncertainty_score":0.2526123},"labels":[],"label_agreement":null},{"id":"W1484996251","doi":"10.1038/cddis.2015.109","title":"Uncoupling Neogenin association with lipid rafts promotes neuronal survival and functional recovery after stroke","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Lipid raft; Biology; Stroke (engine); Cell biology; Central nervous system; Neuroscience; Internal medicine; Signal transduction; Medicine","score_opus":0.030537552133552956,"score_gpt":0.2216374438174189,"score_spread":0.19109989168386593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1484996251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980022,0.00035232448,0.00031228532,0.00020333313,0.00023074463,0.00014505263,0.00005449419,0.000042327913,0.00065729494],"genre_scores_gemma":[0.9976117,0.00005698537,0.000051253977,0.00076353486,0.0002407655,0.000022356557,0.0000075184817,0.0000174711,0.0012284048],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99872303,0.000070278584,0.00013124588,0.0004195515,0.0004023691,0.00025353982],"domain_scores_gemma":[0.9989864,0.00019988336,0.00007942154,0.00009465792,0.00005012531,0.00058951357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015690998,0.00015248962,0.000121529134,0.000044014923,0.00012782891,0.000105705,0.000044039403,0.00003940291,0.00002911026],"category_scores_gemma":[0.0003530429,0.00012807232,0.000034400025,0.00007574403,0.00003891285,0.00026724153,0.00005219488,0.00012195613,0.000015203783],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0075800195,0.00034291687,0.8966714,0.00011531601,0.000018750488,0.0003176021,0.00014034173,0.0011255183,0.09108899,0.0002203552,0.00095657934,0.001422193],"study_design_scores_gemma":[0.011712343,0.0026805783,0.829165,0.0001875496,0.0005702624,0.0000595526,0.00025131833,0.021648664,0.11897104,0.003784903,0.0087702265,0.0021985765],"about_ca_topic_score_codex":0.0000059229787,"about_ca_topic_score_gemma":0.000002226345,"teacher_disagreement_score":0.06750643,"about_ca_system_score_codex":0.00003495811,"about_ca_system_score_gemma":0.00017603778,"threshold_uncertainty_score":0.52226377},"labels":[],"label_agreement":null},{"id":"W1503374894","doi":"10.1038/cddis.2009.23","title":"Structural and functional neuroprotection in glaucoma: role of galantamine-mediated activation of muscarinic acetylcholine receptors","year":2010,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Université de Montréal","funders":"Canadian Institutes of Health Research; Glaucoma Research Foundation; American Health Assistance Foundation","keywords":"Galantamine; Glaucoma; Muscarinic acetylcholine receptor; Medicine; Optic nerve; Nicotinic agonist; Acetylcholine; Intraocular pressure; Pilocarpine; Retinal ganglion cell; Neuroprotection; Neuroscience; Pharmacology; Ophthalmology; Receptor; Internal medicine; Biology; Epilepsy; Donepezil","score_opus":0.005074411750644387,"score_gpt":0.21004487612974826,"score_spread":0.20497046437910388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1503374894","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99928445,0.00023316819,0.000023319704,0.000021990978,0.00011987397,0.00018946729,0.000021153664,0.0000053122826,0.000101258345],"genre_scores_gemma":[0.99945384,0.00010728459,0.00008546903,0.000021610951,0.000094808165,0.000010115945,0.00016553813,0.00001083593,0.000050497918],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993436,0.0000342794,0.00019386961,0.00023145184,0.000086916574,0.00010990849],"domain_scores_gemma":[0.9995411,0.000018218207,0.00010326009,0.00014596463,0.000052650874,0.00013879008],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007407698,0.000108281194,0.00011980801,0.000056233694,0.00002772794,0.0000047582307,0.000042141484,0.000084182735,0.000021991138],"category_scores_gemma":[0.00019871345,0.000100593905,0.00003402788,0.0000750368,0.00006695225,0.0000079968095,0.000065991684,0.000119489574,4.4568904e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026899113,0.000060925187,0.33476323,0.00003061164,0.000005618668,7.552639e-8,0.000019140549,0.0000044203534,0.6640811,0.000013105718,0.000022850987,0.0007299491],"study_design_scores_gemma":[0.0015677667,0.00014076893,0.71336997,0.000008657834,0.000023547569,0.0000025989523,0.00007008344,0.0006293817,0.28355527,0.000057014924,0.00044969047,0.00012525589],"about_ca_topic_score_codex":0.00005127817,"about_ca_topic_score_gemma":0.000019104495,"teacher_disagreement_score":0.38052583,"about_ca_system_score_codex":0.0000035169446,"about_ca_system_score_gemma":0.000057122536,"threshold_uncertainty_score":0.41021004},"labels":[],"label_agreement":null},{"id":"W1533769407","doi":"10.1038/cddis.2015.187","title":"FV-162 is a novel, orally bioavailable, irreversible proteasome inhibitor with improved pharmacokinetics displaying preclinical efficacy with continuous daily dosing","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto; Princess Margaret Cancer Centre","funders":"Leukemia and Lymphoma Society","keywords":"Pharmacology; Pharmacokinetics; Proteasome; Proteasome inhibitor; Dosing; Multiple myeloma; Pharmacodynamics; Tolerability; Bioavailability; In vivo; Prodrug; Bortezomib; Medicine; Chemistry; Biology; Immunology; Adverse effect; Biochemistry","score_opus":0.026378275957210425,"score_gpt":0.265230519640434,"score_spread":0.23885224368322355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1533769407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99326754,0.0025705341,0.0013946184,0.00018581307,0.00008776796,0.0010674784,0.00016437152,0.00004573187,0.0012161493],"genre_scores_gemma":[0.99264574,0.00009136411,0.004224069,0.0009130336,0.0003180081,0.00008481346,0.00016358851,0.000056567584,0.001502833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832016,0.000053161333,0.0002496859,0.0006880226,0.00022504343,0.00046393252],"domain_scores_gemma":[0.9980489,0.000022060975,0.00014600226,0.00039684906,0.00016536725,0.0012208401],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019001152,0.00034126715,0.00026347942,0.000046295845,0.00014243515,0.00013145413,0.00018210559,0.00012719646,0.000026627338],"category_scores_gemma":[0.000090250454,0.0002592428,0.0000701227,0.00010254918,0.00016749433,0.000020740234,0.00015655131,0.00017343884,0.000017512903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018890508,0.0020801392,0.11007573,0.0007111121,0.0002496509,0.00016794688,0.00045960004,0.00008373197,0.85578656,0.00003934556,0.0077184653,0.0037372066],"study_design_scores_gemma":[0.04665065,0.008067319,0.008451183,0.00052947726,0.0011864045,0.00010809375,0.000467287,0.003077851,0.8166574,0.000088671986,0.11184022,0.0028754098],"about_ca_topic_score_codex":0.000020871446,"about_ca_topic_score_gemma":0.0000029291757,"teacher_disagreement_score":0.10412175,"about_ca_system_score_codex":0.000016452244,"about_ca_system_score_gemma":0.00052991195,"threshold_uncertainty_score":0.999986},"labels":[],"label_agreement":null},{"id":"W1551854884","doi":"10.1038/cddis.2015.151","title":"Microglia-derived IL-1β triggers p53-mediated cell cycle arrest and apoptosis in neural precursor cells","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":135,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Krembil Foundation","keywords":"Neurogenesis; Microglia; Cell biology; Biology; Cell cycle; Apoptosis; Programmed cell death; Cell cycle checkpoint; Cancer research; Immunology; Inflammation","score_opus":0.02518712209777207,"score_gpt":0.226672120174418,"score_spread":0.20148499807664594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1551854884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978527,0.000425771,0.000019426445,0.000094602314,0.0004988159,0.0004211913,0.00018616799,0.00007735074,0.0004240147],"genre_scores_gemma":[0.99793655,0.00040032872,0.000041748055,0.0012589999,0.000049548624,0.000030103245,0.000008247983,0.000041542204,0.00023294488],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979733,0.00021622238,0.00026704426,0.0007747181,0.0002611176,0.0005075918],"domain_scores_gemma":[0.9978237,0.00026814142,0.000095747426,0.00026117938,0.000026586522,0.0015246546],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009436048,0.00030472822,0.0002640526,0.00014088134,0.00012137615,0.00013388757,0.00018677773,0.000065950226,0.000017281658],"category_scores_gemma":[0.0002982064,0.00028426113,0.00006378327,0.00021778324,0.00011608401,0.0001851512,0.00013575156,0.00015978212,0.000068732676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038013083,0.0003417634,0.0010649862,0.0000803944,9.1283295e-7,0.00021326572,0.00013676751,0.00006976717,0.997239,0.000018961846,0.00030027848,0.00015377482],"study_design_scores_gemma":[0.0021609478,0.0001837273,0.0011058147,0.000012794768,0.00004369471,0.0000037616599,0.000051276347,0.00502014,0.99058384,0.000079616206,0.000434578,0.0003197846],"about_ca_topic_score_codex":0.000018192903,"about_ca_topic_score_gemma":0.0000023367702,"teacher_disagreement_score":0.0066551333,"about_ca_system_score_codex":0.000018777399,"about_ca_system_score_gemma":0.00010831126,"threshold_uncertainty_score":0.99996096},"labels":[],"label_agreement":null},{"id":"W1569444286","doi":"10.1038/cddis.2015.102","title":"Peptides derived from the dependence receptor ALK are proapoptotic for ALK-positive tumors","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"Fondation de France; Institut National de la Santé et de la Recherche Médicale","keywords":"Anaplastic lymphoma kinase; Cancer research; Neuroblastoma; Apoptosis; Tyrosine kinase; ALK inhibitor; Molecular biology; Crizotinib; Biology; Receptor tyrosine kinase; Cell culture; Kinase; Cytotoxic T cell; Chemistry; Signal transduction; Cell biology; Biochemistry; Medicine; Internal medicine","score_opus":0.035288619861471256,"score_gpt":0.2798446445445675,"score_spread":0.24455602468309623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1569444286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952571,0.0013846038,0.000093439194,0.0010860147,0.000047502486,0.0010621042,0.00026807093,0.00003410547,0.00076707103],"genre_scores_gemma":[0.9973483,0.000055765548,0.0004574554,0.0006627702,0.00012086911,0.00015675032,0.00015708513,0.000019728514,0.0010212405],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99900883,0.000051491206,0.00010512535,0.000308045,0.0002412516,0.00028526454],"domain_scores_gemma":[0.99811053,0.00018402639,0.000045145192,0.00022849145,0.00012261943,0.0013091753],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059185357,0.00014900748,0.00016235169,0.000025308353,0.00012774351,0.000045724388,0.00008014005,0.000025757228,0.000025988926],"category_scores_gemma":[0.0004677937,0.00009278386,0.00007184336,0.000053038224,0.00008021132,0.00007632412,0.000051780167,0.0000855125,0.000066951514],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021837946,0.002796569,0.9032611,0.00055828353,0.000409179,0.002542649,0.0015651572,0.000013140781,0.021783674,0.0002024752,0.03541616,0.009613623],"study_design_scores_gemma":[0.016050143,0.0020642818,0.9161504,0.00057196734,0.0008568904,0.000026541757,0.0018002146,0.00094765285,0.054550216,0.00417644,0.0022955383,0.0005097265],"about_ca_topic_score_codex":0.00006954712,"about_ca_topic_score_gemma":0.00000952232,"teacher_disagreement_score":0.03312062,"about_ca_system_score_codex":0.000039097085,"about_ca_system_score_gemma":0.00029410212,"threshold_uncertainty_score":0.3783616},"labels":[],"label_agreement":null},{"id":"W1904500917","doi":"10.1038/cddis.2015.272","title":"Targeting caspase-6 and caspase-8 to promote neuronal survival following ischemic stroke","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; Toronto Rehabilitation Institute; University of Toronto","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Caspase 3; Retinal ganglion cell; Ischemia; Apoptosis; Caspase; Pharmacology; Medicine; Caspase 2; Biology; Neuroscience; Internal medicine; Retina; Programmed cell death; Biochemistry","score_opus":0.012709852344596765,"score_gpt":0.23159963466150604,"score_spread":0.21888978231690928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1904500917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948205,0.0023339123,0.0014372696,0.00011198347,0.00025275978,0.00022065287,0.000037100486,0.000015692242,0.0007701788],"genre_scores_gemma":[0.99674326,0.00007404394,0.0009057225,0.00023103916,0.0002429876,0.000013569639,0.00016849757,0.000023105908,0.0015977996],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990567,0.00003034716,0.00012888662,0.00039690273,0.00014149351,0.0002456913],"domain_scores_gemma":[0.9988108,0.000005704461,0.000034089324,0.00016620809,0.000040750667,0.0009424342],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014440107,0.00016452432,0.00011828042,0.000031386648,0.00009924052,0.000048634676,0.000058821763,0.000069865404,0.0000051510488],"category_scores_gemma":[0.00009380884,0.0001527236,0.000056641285,0.000037059883,0.00001815379,0.000007339323,0.00013021058,0.00005146646,0.000004723495],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003166368,0.000085135944,0.009983996,0.00006532561,0.000024115403,0.00009507116,0.00010675518,0.00020304759,0.98290104,0.00006838865,0.0032797935,0.0028707134],"study_design_scores_gemma":[0.016201662,0.0031034262,0.046983164,0.00018561122,0.0010936931,0.000072965224,0.0015583584,0.020213066,0.4311546,0.0013873159,0.47348133,0.0045648078],"about_ca_topic_score_codex":0.000021426797,"about_ca_topic_score_gemma":0.0000034775444,"teacher_disagreement_score":0.5517464,"about_ca_system_score_codex":0.00000800305,"about_ca_system_score_gemma":0.000095120035,"threshold_uncertainty_score":0.6227888},"labels":[],"label_agreement":null},{"id":"W1928145000","doi":"10.1038/cddis.2015.238","title":"Transglutaminase 2—a novel inhibitor of adipogenesis","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Blood properties and coagulation","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Institute of Genetics; Canadian Institutes of Health Research","keywords":"Adipogenesis; Cell biology; Adipocyte; Fibronectin; Extracellular matrix; Phosphorylation; Biology; Signal transduction; Cellular differentiation; Lipid droplet; Wnt signaling pathway; Protein kinase A; Adipose tissue; Chemistry; Biochemistry; Mesenchymal stem cell","score_opus":0.03824392059051661,"score_gpt":0.23883163626500836,"score_spread":0.20058771567449174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1928145000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99260885,0.005198024,0.00027435852,0.00022917496,0.000043526717,0.00013566187,0.00001908122,0.000014994705,0.0014763495],"genre_scores_gemma":[0.9985802,0.000033685075,0.00029011702,0.00024902588,0.000076727214,0.0000061935125,0.000017895343,0.000008080066,0.0007380342],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.999592,0.0000063397456,0.00010159302,0.000107294596,0.00010849547,0.000084299725],"domain_scores_gemma":[0.9991873,0.0000055581636,0.000021022295,0.00011481672,0.000057562807,0.00061375956],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004125191,0.000063802996,0.000108773726,0.000028442162,0.000017286466,0.000004676528,0.000017427798,0.000026181668,0.000019111407],"category_scores_gemma":[0.000029183586,0.000049162376,0.000040070092,0.00004370467,0.000025351077,0.000035238598,0.000009112254,0.00002261147,0.0000048187417],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012937459,0.00513148,0.72047395,0.0036976282,0.00015872836,0.0002336056,0.0024488035,0.00011813175,0.18058042,0.0016664296,0.0062642056,0.066289134],"study_design_scores_gemma":[0.027206665,0.002227292,0.7871817,0.0004285261,0.0033396648,0.000039164912,0.0011140895,0.008627245,0.14338899,0.0010411382,0.024580035,0.0008255147],"about_ca_topic_score_codex":0.00002577911,"about_ca_topic_score_gemma":5.7340185e-7,"teacher_disagreement_score":0.066707715,"about_ca_system_score_codex":0.000006275727,"about_ca_system_score_gemma":0.00012908093,"threshold_uncertainty_score":0.20047835},"labels":[],"label_agreement":null},{"id":"W1950475967","doi":"10.1038/cddis.2015.310","title":"Succinate dehydrogenase/complex II activity obligatorily links mitochondrial reserve respiratory capacity to cell survival in cardiac myocytes","year":2015,"lang":"en","type":"editorial","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Succinate dehydrogenase; Mitochondrion; Myocyte; Cell biology; Cell; Mitochondrial respiratory chain; Respiratory system; Cell survival; Biology; Biochemistry; In vitro; Anatomy","score_opus":0.0269886805745466,"score_gpt":0.26612456933831713,"score_spread":0.23913588876377054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1950475967","genre_codex":"empirical","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.59074134,0.0037589935,0.00010273443,0.000061902836,0.39959252,0.0009653528,0.002749862,0.000044275697,0.0019830365],"genre_scores_gemma":[0.1578977,0.0007615429,0.0004574856,0.00065512204,0.8297681,0.0003970797,0.0041384012,0.00024824915,0.0056763054],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959198,0.0007556522,0.0004790171,0.0014997125,0.00060265267,0.00074312906],"domain_scores_gemma":[0.99625254,0.0001311563,0.00021713017,0.0010353505,0.00040625222,0.0019575758],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00056578376,0.0006922732,0.0008155748,0.00022274289,0.00023583161,0.000088547546,0.00042600976,0.0018737068,0.000036071986],"category_scores_gemma":[0.0017133852,0.0007177987,0.00033693353,0.00020822177,0.000110723115,0.000014722397,0.00057126407,0.0009889518,0.000045266657],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030912245,0.00024493772,0.0013150255,0.00020271944,0.000030780076,0.00007213803,0.00007152036,0.000030167581,0.18363161,0.000009650974,0.81124216,0.000058035243],"study_design_scores_gemma":[0.0024881423,0.0008020977,0.00042320378,0.000033011398,0.0001306992,4.1656028e-7,0.000018985953,0.000014934942,0.027990712,0.00012214779,0.9671506,0.0008250028],"about_ca_topic_score_codex":0.0003440517,"about_ca_topic_score_gemma":0.00021756772,"teacher_disagreement_score":0.43284363,"about_ca_system_score_codex":0.00011296475,"about_ca_system_score_gemma":0.0014483496,"threshold_uncertainty_score":0.99952734},"labels":[],"label_agreement":null},{"id":"W1964670826","doi":"10.1038/cddis.2013.521","title":"Plasmodium falciparum signal recognition particle components and anti-parasitic effect of ivermectin in blocking nucleo-cytoplasmic shuttling of SRP","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Alberta","keywords":"Plasmodium falciparum; Signal recognition particle; Cell biology; Endoplasmic reticulum; Biology; Cytoplasm; Nuclear transport; Importin; Ribonucleoprotein; Nuclear localization sequence; RNA; Biochemistry; Cell nucleus; Gene; Malaria; Ribosome; Immunology","score_opus":0.012558001782647099,"score_gpt":0.2387903100424516,"score_spread":0.2262323082598045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964670826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984489,0.00074882404,0.00007435797,0.000025741683,0.000043023065,0.0002463093,0.00001667061,0.000013191989,0.00038298298],"genre_scores_gemma":[0.99971765,0.00008260621,0.000059916736,0.000063813604,0.000022266677,0.0000058865653,0.000025503572,0.000011502161,0.000010857637],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991534,0.000095007155,0.00022218403,0.00020170349,0.00012911521,0.00019863724],"domain_scores_gemma":[0.99937207,0.00014090548,0.000075215765,0.0001042388,0.000024047702,0.00028355545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019463927,0.00012326796,0.00031617115,0.00008908945,0.000041422154,0.000008239892,0.000028475546,0.000041897416,0.000022286065],"category_scores_gemma":[0.00011382488,0.00011015461,0.00004718517,0.000077956094,0.00007603778,0.000059009686,0.00001955272,0.00007043258,0.0000042928045],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014370262,0.00027975373,0.9062581,0.001270682,0.000007796873,0.000019563586,0.00019619016,0.00006514851,0.08723271,0.000035433648,0.000008791176,0.0031887938],"study_design_scores_gemma":[0.009272173,0.00040512122,0.86137825,0.0003114885,0.00046058057,0.000005647841,0.00009995203,0.013623012,0.11389123,0.0003478106,0.000015729867,0.00018902241],"about_ca_topic_score_codex":0.00004703154,"about_ca_topic_score_gemma":0.0000014641707,"teacher_disagreement_score":0.044879884,"about_ca_system_score_codex":0.0000058570326,"about_ca_system_score_gemma":0.000025163405,"threshold_uncertainty_score":0.44919744},"labels":[],"label_agreement":null},{"id":"W1967964064","doi":"10.1038/cddis.2011.85","title":"The p75 receptor mediates axon growth inhibition through an association with PIR-B","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; York University","keywords":"Protein tyrosine phosphatase; Receptor; Axon; Cell biology; Myelin-associated glycoprotein; Biology; Signal transduction; Myelin; Phosphatase; Low-affinity nerve growth factor receptor; Proto-oncogene tyrosine-protein kinase Src; Molecular biology; Nerve growth factor; Biochemistry; Neuroscience; Central nervous system; Phosphorylation","score_opus":0.028379759080257888,"score_gpt":0.22624110130644418,"score_spread":0.1978613422261863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967964064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946529,0.00016046785,0.00013563066,0.00045757936,0.00017970687,0.00017772884,0.000029113235,0.000053519412,0.004153354],"genre_scores_gemma":[0.9981131,0.00038488844,0.00010829088,0.00057792605,0.00014102539,0.00002940722,0.000026960537,0.000009472588,0.00060892495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919945,0.00012580454,0.000099350764,0.00023294994,0.0001775501,0.00016487335],"domain_scores_gemma":[0.9994752,0.00007405895,0.000085498636,0.000121831814,0.000041334748,0.00020209499],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001107676,0.00009302239,0.000055873876,0.000014911333,0.00042217615,0.00007559804,0.00005643476,0.000039405277,0.00003111806],"category_scores_gemma":[0.00017291299,0.000055593737,0.000022386814,0.0000800199,0.000055144243,0.00051227683,0.000015121409,0.00006503755,0.000026315503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002634019,0.0014237149,0.15745972,0.00015671703,0.00001644845,0.00007915425,0.0036985788,0.00001036454,0.71431154,0.107234016,0.009698787,0.003276933],"study_design_scores_gemma":[0.0006073826,0.00029014368,0.012240901,0.000013194255,0.00004682182,0.0000011426772,0.00007221986,0.0001393583,0.9738586,0.010973258,0.0015555976,0.00020138182],"about_ca_topic_score_codex":0.000021082993,"about_ca_topic_score_gemma":0.000008178367,"teacher_disagreement_score":0.25954705,"about_ca_system_score_codex":0.000021764557,"about_ca_system_score_gemma":0.000043562057,"threshold_uncertainty_score":0.32470804},"labels":[],"label_agreement":null},{"id":"W1971615932","doi":"10.1038/cddis.2014.338","title":"Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; McGill University Health Centre; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Involution (esoterism); Cell biology; Biology; RAC1; Mammary gland; Rac GTP-Binding Proteins; Signal transduction; Neuroscience","score_opus":0.010587217514154286,"score_gpt":0.21088491827019953,"score_spread":0.20029770075604525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971615932","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9792374,0.019863617,0.0002846276,0.00006547199,0.000040719682,0.00014800776,0.000009674387,0.0000086811315,0.00034184326],"genre_scores_gemma":[0.9989637,0.00069363625,0.000041848845,0.000111922614,0.000012330318,0.000007523412,0.000046867895,0.0000045284846,0.00011763256],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99931705,0.00015874616,0.00016256844,0.00018315855,0.000025631663,0.00015285776],"domain_scores_gemma":[0.9996,0.00011298287,0.00007112011,0.00014786152,0.000018035042,0.000049994094],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022951675,0.0001052967,0.00014456359,0.00005190798,0.00010986903,0.000019469902,0.0000663203,0.00007174432,0.000007215505],"category_scores_gemma":[0.00003464579,0.00007557423,0.000026467706,0.00004542737,0.000082290026,0.00010467707,0.00004953558,0.000075313845,0.0000020776342],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004981404,0.00026598197,0.48980978,0.00034136267,0.000019461944,0.000006963792,0.001074376,0.00002103564,0.49954897,0.0020156347,0.00026967635,0.0061286017],"study_design_scores_gemma":[0.0023300883,0.00014939292,0.97652215,0.000056742236,0.000059831815,0.000011167273,0.00015240138,0.0009829128,0.01576436,0.0029737677,0.0008253483,0.00017181992],"about_ca_topic_score_codex":0.000074815754,"about_ca_topic_score_gemma":0.0000032969788,"teacher_disagreement_score":0.48671237,"about_ca_system_score_codex":0.000006146176,"about_ca_system_score_gemma":0.00002887017,"threshold_uncertainty_score":0.30818275},"labels":[],"label_agreement":null},{"id":"W1974168359","doi":"10.1038/cddis.2013.296","title":"Knockdown of specific host factors protects against influenza virus-induced cell death","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Children's Hospital Research Institute of Manitoba; Public Health Agency of Canada; University of Manitoba; Research Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Manitoba Health Research Council; Canadian Institutes of Health Research; University of Ottawa; Health Sciences Centre Foundation","keywords":"Gene knockdown; Gene silencing; Biology; Programmed cell death; Viral replication; RNA interference; Virus; Virology; Influenza A virus; Gene; Cell biology; Apoptosis; Genetics; RNA","score_opus":0.02132740291401366,"score_gpt":0.23137369303123032,"score_spread":0.21004629011721665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974168359","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98620003,0.007431688,0.000013263835,0.00002274389,0.00025768124,0.000632177,0.0000785092,0.00005530457,0.005308602],"genre_scores_gemma":[0.99638814,0.00025997974,0.000017774857,0.0002864504,0.000020011552,0.000049403658,0.000063900945,0.000025821364,0.0028884988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867755,0.00016394976,0.00033078733,0.00034898915,0.0000461294,0.00043259005],"domain_scores_gemma":[0.9990803,0.00009375191,0.00013470127,0.00039792014,0.000091515976,0.00020181545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006662442,0.00029226835,0.00031793237,0.0001454987,0.00017054647,0.000037463313,0.00020357795,0.00018539562,0.0008983823],"category_scores_gemma":[0.00006144653,0.00023251493,0.0001424953,0.00007841379,0.00011722941,0.00014428953,0.000112298614,0.00023247073,0.0004866775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000581699,0.00032011516,0.008889913,0.00009845534,0.000029686107,0.000007964545,0.00026575496,6.1030516e-7,0.98747915,0.000087720204,0.0017063923,0.000532519],"study_design_scores_gemma":[0.0015617857,0.00029884072,0.09705007,0.000046420093,0.000033576358,0.000001747666,0.0003221431,0.0000037266932,0.8836984,0.000043799297,0.016629815,0.00030967675],"about_ca_topic_score_codex":0.00014842117,"about_ca_topic_score_gemma":0.0000014304807,"teacher_disagreement_score":0.10378077,"about_ca_system_score_codex":0.000024793102,"about_ca_system_score_gemma":0.00013384226,"threshold_uncertainty_score":0.9836656},"labels":[],"label_agreement":null},{"id":"W1974316110","doi":"10.1038/cddis.2014.554","title":"Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; McGill University","keywords":"mTORC1; Protein kinase B; PI3K/AKT/mTOR pathway; mTORC2; Integrated stress response; Cell biology; Biology; Downregulation and upregulation; Programmed cell death; Oxidative stress; Phosphorylation; eIF2; Cancer research; Signal transduction; Apoptosis; Translation (biology); Biochemistry","score_opus":0.03138133318313664,"score_gpt":0.2762881265004813,"score_spread":0.24490679331734466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974316110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759716,0.0011059435,0.00053253205,0.00010021693,0.000062262254,0.0002645882,0.00023252112,0.0000023054254,0.000102490885],"genre_scores_gemma":[0.99957746,0.000053803702,0.0001042436,0.00007001547,0.000023545883,0.000018389708,0.000050277966,0.000007356895,0.00009489757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993347,0.00012007749,0.00017439868,0.00015935051,0.00012199428,0.000089475216],"domain_scores_gemma":[0.99937445,0.00007774794,0.00009645133,0.00022932877,0.00009677229,0.00012522424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013362226,0.00008753663,0.000080442594,0.00003047876,0.000036755995,0.0000069659013,0.0001052991,0.000047178713,0.0000073391434],"category_scores_gemma":[0.00023610757,0.00005902031,0.000042559557,0.000090906855,0.000039831928,0.000006907581,0.000054712742,0.000030788222,8.3158915e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034081535,0.000082564184,0.06697834,0.000028982724,0.000005831015,0.0000012657865,0.0007395419,0.0019668415,0.9253146,0.0000029359535,0.00009783684,0.0013730911],"study_design_scores_gemma":[0.00080505566,0.00014201777,0.12433091,0.00003122078,0.000024539788,2.3171437e-7,0.00009075615,0.00039954606,0.873427,0.00009124657,0.0005719151,0.00008557801],"about_ca_topic_score_codex":0.00002218832,"about_ca_topic_score_gemma":0.000053858297,"teacher_disagreement_score":0.057352565,"about_ca_system_score_codex":0.000018581573,"about_ca_system_score_gemma":0.0001329009,"threshold_uncertainty_score":0.24067783},"labels":[],"label_agreement":null},{"id":"W1974623973","doi":"10.1038/cddis.2014.391","title":"Gefitinib targets ZAP-70-expressing chronic lymphocytic leukemia cells and inhibits B-cell receptor signaling","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Manitoba; University of Manitoba","funders":"CancerCare Manitoba Foundation; CLL Global Research Foundation","keywords":"Gefitinib; Syk; Chronic lymphocytic leukemia; Cancer research; Tyrosine kinase; Protein kinase B; Bruton's tyrosine kinase; Viability assay; breakpoint cluster region; Apoptosis; Signal transduction; Leukemia; Biology; Medicine; Immunology; Epidermal growth factor receptor; Receptor; Internal medicine; Cell biology","score_opus":0.0122857229256854,"score_gpt":0.24644626377914572,"score_spread":0.23416054085346033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974623973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97841215,0.014349191,0.00035754868,0.00007143537,0.00016124295,0.0005722976,0.000028818215,0.00013185198,0.0059154616],"genre_scores_gemma":[0.99329007,0.0012909882,0.0004940195,0.0007772483,0.00061501074,0.000039633487,0.00008107674,0.00008197962,0.003329998],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970597,0.00012505408,0.0004252676,0.0008263622,0.00069746276,0.0008661404],"domain_scores_gemma":[0.996248,0.00033269916,0.00011972718,0.0005466028,0.00011476139,0.0026381891],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004442953,0.0004006917,0.00048204244,0.00016343824,0.0002869836,0.00014887561,0.00016397728,0.00020604962,0.00043611243],"category_scores_gemma":[0.00033989694,0.00035852133,0.00012567842,0.00016409121,0.00023035833,0.00017022583,0.0002495061,0.00029110166,0.0001979542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.004128141,0.0006445362,0.004039036,0.018229883,0.00015724442,0.0018592669,0.0014112474,0.0019196433,0.91564304,0.00047013804,0.019810133,0.031687714],"study_design_scores_gemma":[0.06784095,0.0007842292,0.00043776905,0.0018656744,0.0005593271,0.00013343981,0.00018095542,0.34065086,0.55876786,0.0005024489,0.0269305,0.0013459735],"about_ca_topic_score_codex":0.00021551627,"about_ca_topic_score_gemma":0.0000028626846,"teacher_disagreement_score":0.35687515,"about_ca_system_score_codex":0.010240625,"about_ca_system_score_gemma":0.019281222,"threshold_uncertainty_score":0.9998867},"labels":[],"label_agreement":null},{"id":"W1975837020","doi":"10.1038/cddis.2014.449","title":"TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Sahlgrenska Akademin; Göteborgs Universitet; Åhlén-stiftelsen; IngaBritt och Arne Lundbergs Forskningsstiftelse; Stem Cell Network; Stiftelserna Wilhelm och Martina Lundgrens; Barncancerfonden; Cancerfonden","keywords":"Progenitor cell; Neural stem cell; Nestin; Biology; Neuroblastoma; Cancer research; Cell biology; Stem cell; Cell culture; Genetics","score_opus":0.006204629592097185,"score_gpt":0.21474052993815504,"score_spread":0.20853590034605785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975837020","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99848664,0.0003226469,0.0000029382516,0.000087069086,0.000021021637,0.00042375285,0.000017632072,0.00003266303,0.0006056232],"genre_scores_gemma":[0.9995849,0.00004578373,0.0001562004,0.00007158865,0.000016834665,0.000022261125,0.000012137602,0.000021415857,0.00006886716],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99899143,0.00006898109,0.00015051031,0.00030316986,0.00021589336,0.0002700182],"domain_scores_gemma":[0.9988957,0.00013294102,0.000056993904,0.00015740297,0.000045340985,0.000711588],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003129647,0.00017681794,0.00024829077,0.00006797227,0.00004359362,0.000020144147,0.000036070676,0.000023318169,0.000025789817],"category_scores_gemma":[0.00011022969,0.000121764766,0.000031143536,0.00009774444,0.000084528416,0.00006674902,0.000052187104,0.00009746652,0.000004015123],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003533411,0.0013931704,0.98529494,0.00052095467,0.000041011353,0.0006071005,0.00010263668,0.0000050816034,0.0066166655,0.000053774507,0.00005097015,0.0017802761],"study_design_scores_gemma":[0.01155386,0.0077325967,0.91845626,0.00041279793,0.00028346246,0.000067077446,0.00028298388,0.0019653337,0.05808974,0.0006743594,0.0001330074,0.00034851217],"about_ca_topic_score_codex":0.000080181264,"about_ca_topic_score_gemma":0.000035757083,"teacher_disagreement_score":0.06683868,"about_ca_system_score_codex":0.000011948037,"about_ca_system_score_gemma":0.00010881444,"threshold_uncertainty_score":0.4965423},"labels":[],"label_agreement":null},{"id":"W1976585056","doi":"10.1038/cddis.2010.64","title":"Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98","year":2010,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":158,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"EZH2; Nasopharyngeal carcinoma; microRNA; Carcinogenesis; Biology; Cancer research; Gene expression profiling; Polycomb-group proteins; PRC2; Enhancer; Regulation of gene expression; In silico; Tumor progression; Epigenetics; Gene expression; Gene; Genetics; Medicine; Repressor; Internal medicine; Radiation therapy","score_opus":0.00559818401351138,"score_gpt":0.22362400107147926,"score_spread":0.21802581705796786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976585056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812668,0.017640173,0.000007711806,0.00011565121,0.00006674668,0.00029900367,0.00042560717,0.0000067622145,0.00017153414],"genre_scores_gemma":[0.99839574,0.0005083042,0.0001027574,0.00021185448,0.00004959405,0.000022974025,0.00032661812,0.000020573658,0.00036157566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988413,0.00004475127,0.0002421077,0.000522697,0.000107367705,0.0002418011],"domain_scores_gemma":[0.99901664,0.000013657173,0.00010769788,0.00034067713,0.000058518344,0.00046282445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006886857,0.00021816978,0.00020952479,0.00005314141,0.00005405825,0.000026849653,0.000088135734,0.00017778669,0.00008455223],"category_scores_gemma":[0.000036134352,0.00021702846,0.0000559602,0.000057336147,0.00016141072,0.000012407946,0.00011128275,0.00009660555,0.0000015174033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004692317,0.00017027107,0.056535102,0.00023329644,0.000017226808,0.000008095989,0.000099513,3.1093467e-7,0.93373644,0.000009606002,0.008186554,0.0005343512],"study_design_scores_gemma":[0.0022718564,0.00015633376,0.35227016,0.0000461209,0.000095949166,0.000005372737,0.000019979498,0.00028319776,0.6394611,0.0002698362,0.004776897,0.00034322785],"about_ca_topic_score_codex":0.00008023401,"about_ca_topic_score_gemma":0.000016003505,"teacher_disagreement_score":0.29573503,"about_ca_system_score_codex":0.000007708212,"about_ca_system_score_gemma":0.00009014124,"threshold_uncertainty_score":0.8850164},"labels":[],"label_agreement":null},{"id":"W1977485776","doi":"10.1038/cddis.2012.160","title":"miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Juravinski Cancer Centre","funders":"National Cancer Institute; Associazione Italiana per la Ricerca sul Cancro","keywords":"Downregulation and upregulation; Biology; Ectopic expression; Cancer research; microRNA; Cancer; Messenger RNA; Long non-coding RNA; Cell culture; Gene; Genetics","score_opus":0.00856662084487661,"score_gpt":0.25038223329188375,"score_spread":0.24181561244700714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977485776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93650824,0.06290025,0.00024013613,0.000019796886,0.00005858392,0.000111671616,0.000055131164,0.0000037625553,0.000102418024],"genre_scores_gemma":[0.99817383,0.001187239,0.00019593968,0.000053465305,0.0001097045,0.000022691702,0.00006270053,0.0000089831055,0.00018541711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994716,0.00004399654,0.00009587673,0.00016977062,0.00006559282,0.00015316582],"domain_scores_gemma":[0.99939203,0.000009246114,0.000059528495,0.00014129546,0.000038183887,0.00035969852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000056530997,0.00009305988,0.00008015707,0.000027980821,0.000046166573,0.0000073385113,0.000039842776,0.000046910314,0.000026256219],"category_scores_gemma":[0.000045398225,0.0000813736,0.000030245732,0.000030748433,0.000048248174,0.000008130818,0.000059435908,0.000018897164,9.4132366e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036148296,0.00007008434,0.056145523,0.00013666264,0.00000635108,0.0000010195114,0.00002544755,0.000007414987,0.9422325,0.000009500195,0.00054831005,0.0004557079],"study_design_scores_gemma":[0.00043400493,0.000034150064,0.23984666,0.000037578746,0.000049416805,0.0000010988233,0.000023833496,0.00002486413,0.7550189,0.000058800902,0.004347301,0.00012340436],"about_ca_topic_score_codex":0.0000062830577,"about_ca_topic_score_gemma":6.284091e-7,"teacher_disagreement_score":0.1872136,"about_ca_system_score_codex":0.0000047116564,"about_ca_system_score_gemma":0.00006661628,"threshold_uncertainty_score":0.3318319},"labels":[],"label_agreement":null},{"id":"W1981542225","doi":"10.1038/cddis.2014.303","title":"The androgen receptor mediates antiapoptotic function in myometrial cells","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of British Columbia","funders":"Canadian Institutes of Health Research; National Institutes of Health; Prostate Cancer Canada","keywords":"Cell biology; Signal transduction; Biology; Androgen receptor; Protein kinase B; PI3K/AKT/mTOR pathway; Apoptosis; Endocrinology; Programmed cell death; Internal medicine; Cancer research; Medicine","score_opus":0.00853471252268561,"score_gpt":0.2034057711831273,"score_spread":0.1948710586604417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981542225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9428883,0.052065264,0.000086673346,0.00015054319,0.0022859413,0.00031192353,0.000018684634,0.00003148186,0.0021611531],"genre_scores_gemma":[0.9974644,0.00046309872,0.000005542727,0.000060540824,0.00012760329,0.000020429734,0.000041387,0.00000790239,0.0018090649],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990458,0.00026329453,0.00016698775,0.00027415738,0.000027218957,0.00022252851],"domain_scores_gemma":[0.9994109,0.00019668383,0.000055567583,0.00023587995,0.000026386728,0.00007455513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034850245,0.00010825951,0.00013614997,0.00006222091,0.00018150677,0.00002464018,0.00008518263,0.000100128105,0.00010057591],"category_scores_gemma":[0.0002165424,0.000070675516,0.00004688118,0.00010060829,0.00008317172,0.000053879605,0.000033307344,0.00011636539,0.00032669658],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002976729,0.00052527635,0.55384654,0.00036843412,0.00015152179,0.000009288365,0.0006473294,0.00002204213,0.36986166,0.0046985135,0.023044892,0.043847784],"study_design_scores_gemma":[0.011472048,0.000899558,0.4586084,0.00018828837,0.00034130234,0.000008084556,0.0004662869,0.000031171803,0.17294793,0.009584047,0.3444614,0.0009914531],"about_ca_topic_score_codex":0.000019111867,"about_ca_topic_score_gemma":0.0000026290684,"teacher_disagreement_score":0.32141653,"about_ca_system_score_codex":0.000007835444,"about_ca_system_score_gemma":0.000035008212,"threshold_uncertainty_score":0.41991323},"labels":[],"label_agreement":null},{"id":"W1982320234","doi":"10.1038/cddis.2013.59","title":"Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":143,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Krembil Foundation","keywords":"Puma; Microglia; Apoptosis; Family member; Cell biology; Tumor necrosis factor alpha; Chemistry; Biology; Inflammation; Immunology; Biochemistry; Medicine","score_opus":0.030235606340618407,"score_gpt":0.22611370756538082,"score_spread":0.1958781012247624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982320234","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980249,0.000037440255,0.000171254,0.0005558646,0.0002507081,0.0005541199,0.00002441103,0.000027239344,0.00035405892],"genre_scores_gemma":[0.9975032,0.000046850746,0.00004724884,0.0018139259,0.000029031411,0.00006204876,0.0000047972458,0.000013802273,0.00047908456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988333,0.00017754921,0.00025107843,0.0003248567,0.00023839824,0.00017484627],"domain_scores_gemma":[0.99939346,0.00007046618,0.000105950836,0.00019021955,0.00003817662,0.0002016949],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000044205055,0.00014554165,0.00011211418,0.00008001465,0.00011955981,0.00006733484,0.00015429022,0.00004054288,0.00012804923],"category_scores_gemma":[0.00006396194,0.00011180441,0.00006986403,0.00016768296,0.00006119501,0.00034920347,0.000033102482,0.0001083903,0.000025486348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044517055,0.00010835496,0.00017386823,0.000032495373,6.132742e-7,8.153695e-7,0.000113713744,0.00014062875,0.99837625,0.00031607752,0.00014678687,0.00054585276],"study_design_scores_gemma":[0.000539729,0.000023244933,0.015816618,0.000011307407,0.000009705752,6.006669e-7,0.000020831496,0.0041206004,0.9787142,0.0005512511,0.00008013824,0.00011172886],"about_ca_topic_score_codex":0.000015269601,"about_ca_topic_score_gemma":0.000001047554,"teacher_disagreement_score":0.019662032,"about_ca_system_score_codex":0.000010577201,"about_ca_system_score_gemma":0.000051715073,"threshold_uncertainty_score":0.45592514},"labels":[],"label_agreement":null},{"id":"W1982422096","doi":"10.1038/cddis.2014.144","title":"Impaired mitochondrial respiration promotes dendritic branching via the AMPK signaling pathway","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; Deutsches Zentrum für Neurodegenerative Erkrankungen","keywords":"AMPK; Cell biology; Biology; Mitochondrion; Oxidative phosphorylation; AMP-activated protein kinase; Signal transduction; Protein kinase A; Caenorhabditis elegans; PI3K/AKT/mTOR pathway; Kinase; Biochemistry; Gene","score_opus":0.008557369934105817,"score_gpt":0.20792733388074064,"score_spread":0.1993699639466348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982422096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94797957,0.0012090019,0.04994847,0.00015719196,0.0002503599,0.00025256758,0.00000980149,0.00001880606,0.00017420988],"genre_scores_gemma":[0.9975709,0.000024713803,0.000652995,0.000726885,0.0007060436,0.0000193954,0.0000730921,0.000022134429,0.00020384748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999048,0.0001162421,0.00015860534,0.000329154,0.00011873453,0.00022927318],"domain_scores_gemma":[0.99927896,0.000020002823,0.000055753353,0.00032610056,0.00004559847,0.00027358704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014522584,0.00015492745,0.00010031894,0.00002105741,0.0002558999,0.00009313567,0.00013384837,0.000073391726,0.0000098641385],"category_scores_gemma":[0.00015808565,0.000122023026,0.0000752878,0.000029677054,0.000059994883,0.000005895138,0.00006472297,0.0000718534,0.0000074963914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001030467,0.000077366276,0.004516882,0.00007448319,0.000012483248,0.0000037177595,0.0002919274,0.00026776243,0.99181074,0.000107471344,0.0002424098,0.002491685],"study_design_scores_gemma":[0.0033076305,0.00086352526,0.015892792,0.00006598257,0.00030084865,0.000016761343,0.00012587599,0.016830094,0.9375166,0.010534468,0.013431558,0.0011138413],"about_ca_topic_score_codex":0.000019733188,"about_ca_topic_score_gemma":0.000012353426,"teacher_disagreement_score":0.054294143,"about_ca_system_score_codex":0.0000050740473,"about_ca_system_score_gemma":0.00006796754,"threshold_uncertainty_score":0.49759546},"labels":[],"label_agreement":null},{"id":"W1986960660","doi":"10.1038/cddis.2013.348","title":"Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":179,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Science and Technology Commission of Shanghai Municipality; Chinese Academy of Sciences; Shanghai Municipal Education Commission; National Natural Science Foundation of China","keywords":"Ccaat-enhancer-binding proteins; Osteoblast; Adipocyte; DNA methylation; Endocrinology; Stromal cell; Internal medicine; Wnt signaling pathway; Chemistry; Bone marrow; Adipogenesis; Methylation; Cancer research; Biology; Cell biology; Adipose tissue; Medicine; Signal transduction; Transcription factor; Gene expression; In vitro; Biochemistry","score_opus":0.0055861567353664866,"score_gpt":0.206196500584961,"score_spread":0.2006103438495945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986960660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98515797,0.0124727925,0.00070815167,0.00018430808,0.000113251044,0.00047362992,0.0005015605,0.000023711551,0.00036464204],"genre_scores_gemma":[0.9955708,0.00013676193,0.0012579648,0.00091224373,0.00021700913,0.0001005415,0.0007059255,0.000031626507,0.0010671543],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986701,0.00008130623,0.00020001901,0.0005573513,0.00015460706,0.00033664206],"domain_scores_gemma":[0.99825305,0.000022595672,0.000060194885,0.00037266526,0.000060741055,0.0012307795],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057041212,0.00024871842,0.00019412464,0.000042860793,0.00008499543,0.000099715464,0.00011947611,0.000103567414,0.0002766651],"category_scores_gemma":[0.00008642295,0.00022847453,0.00009156307,0.0000612755,0.000047039302,0.000019438345,0.00012595119,0.000055017,0.00013250523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026660284,0.00020837228,0.007956331,0.000036672565,0.000022995737,0.0000080793725,0.000040332736,0.0000070572373,0.96735144,0.000007975381,0.019161826,0.004932322],"study_design_scores_gemma":[0.0025904728,0.0003765386,0.14639641,0.00002995701,0.0002827455,9.895144e-7,0.00009444614,0.00020086397,0.82322556,0.0011317953,0.024775013,0.00089519646],"about_ca_topic_score_codex":0.00015892918,"about_ca_topic_score_gemma":0.0000069551706,"teacher_disagreement_score":0.14412586,"about_ca_system_score_codex":0.000005989368,"about_ca_system_score_gemma":0.000072910465,"threshold_uncertainty_score":0.9316921},"labels":[],"label_agreement":null},{"id":"W1987742470","doi":"10.1038/cddis.2013.418","title":"Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic response","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; Faculty of Medicine and Dentistry, University of Alberta; Canadian Institutes of Health Research; National Institutes of Health; Welch Foundation; University of Alberta; Alberta Innovates; King Saud University; Alberta Innovates - Health Solutions","keywords":"Autophagy; Cell biology; Programmed cell death; Viability assay; Mitochondrion; Epoxygenase; Biology; Apoptosis; Arachidonic acid; Chemistry; Biochemistry; Enzyme","score_opus":0.0064772218242226745,"score_gpt":0.22214129855637121,"score_spread":0.21566407673214855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987742470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99738187,0.0016698338,0.00009917605,0.00011672553,0.000095433,0.0004685484,0.00006175418,0.000027108468,0.00007957808],"genre_scores_gemma":[0.9977913,0.000119101926,0.0002673576,0.00047275706,0.000118947995,0.000094784125,0.00016119088,0.000024387055,0.00095020246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888766,0.00016890555,0.00016335302,0.0004110109,0.00009411955,0.0002749346],"domain_scores_gemma":[0.9990611,0.000011932035,0.000058000787,0.00025868282,0.00007074127,0.00053953397],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001310028,0.00016719215,0.00013601074,0.000039194514,0.00018599675,0.00005465713,0.00008429361,0.00009698704,0.00006442997],"category_scores_gemma":[0.00004873196,0.00015447295,0.000062126,0.00004825971,0.000042392116,0.000018197788,0.00007753262,0.000078379424,0.000017301358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044760422,0.000084862906,0.004812497,0.000036952682,0.000010668423,0.000008788389,0.000026168525,0.000034295605,0.9926505,0.0000044565368,0.001444019,0.00043919022],"study_design_scores_gemma":[0.0015998334,0.00044215348,0.10321192,0.000008624466,0.000081717975,0.0000032851644,0.000071604,0.0023003991,0.88659716,0.0002138031,0.0050055725,0.00046391244],"about_ca_topic_score_codex":0.000023909544,"about_ca_topic_score_gemma":2.7136042e-7,"teacher_disagreement_score":0.10605332,"about_ca_system_score_codex":0.000010259452,"about_ca_system_score_gemma":0.00008366471,"threshold_uncertainty_score":0.6299224},"labels":[],"label_agreement":null},{"id":"W1987978369","doi":"10.1038/cddis.2013.321","title":"ING1 induces apoptosis through direct effects at the mitochondria","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Cell biology; Biology; Mitochondrion; Chromatin; Chromatin remodeling; Genetics; Gene","score_opus":0.006311918700635184,"score_gpt":0.21329359711926926,"score_spread":0.20698167841863407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987978369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98867434,0.0039043236,0.00007546801,0.00014407284,0.00018008884,0.00035825756,0.00000989999,0.00001998698,0.006633547],"genre_scores_gemma":[0.994165,0.00023445055,0.00027547788,0.0010118304,0.00013131392,0.00014300155,0.00004955885,0.000017441354,0.003971949],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992659,0.00005586287,0.00008181157,0.0003042415,0.00008649802,0.00020568604],"domain_scores_gemma":[0.99931484,0.00002600568,0.000035083365,0.00034631664,0.000025272502,0.00025245413],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000035075227,0.00014009644,0.00008803031,0.000009411706,0.00014043885,0.000047545225,0.00011710919,0.000068245434,0.00005690908],"category_scores_gemma":[0.00009319701,0.000094441886,0.000074504875,0.000033858352,0.00004912963,0.0000063936504,0.00017035306,0.00004092566,0.00007812342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000515645,0.00006498799,0.0022282319,0.000068908514,0.000023521949,0.0000030304807,0.000049316088,0.0000027152767,0.9804611,0.000055718163,0.015805779,0.0011851351],"study_design_scores_gemma":[0.0004321788,0.00010353057,0.003535531,0.00001222497,0.00006458574,0.0000011888515,0.000028244565,0.000028025877,0.9823866,0.0009452963,0.012269266,0.00019336074],"about_ca_topic_score_codex":0.000036871203,"about_ca_topic_score_gemma":0.000002126482,"teacher_disagreement_score":0.005490621,"about_ca_system_score_codex":0.000007296164,"about_ca_system_score_gemma":0.00003467234,"threshold_uncertainty_score":0.38512284},"labels":[],"label_agreement":null},{"id":"W1989727926","doi":"10.1038/cddis.2014.423","title":"Serpina3n accelerates tissue repair in a diabetic mouse model of delayed wound healing","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; St. Paul's Hospital; University of British Columbia","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Mitacs; Canadian Diabetes Association","keywords":"Wound healing; Granulation tissue; Fibronectin; Extracellular matrix; Fibroblast; Inflammation; Angiogenesis; Medicine; Pathology; Immunology; Chemistry; Cell biology; Biology; Cancer research; Biochemistry; In vitro","score_opus":0.024462763509620334,"score_gpt":0.28195421408816645,"score_spread":0.2574914505785461,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989727926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972782,0.0012474344,0.00020070237,0.00018137367,0.000019874073,0.00025018316,0.000035903697,0.00005147103,0.0007348552],"genre_scores_gemma":[0.9968329,0.00013206889,0.0010707526,0.00037253066,0.00003133352,0.000022476319,0.000047424914,0.00001687938,0.001473607],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99921954,0.000022532082,0.00020598187,0.00022819958,0.000109622124,0.00021412199],"domain_scores_gemma":[0.99914587,0.000034937708,0.000041083757,0.00022821619,0.00003789155,0.0005119988],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100858786,0.00012436131,0.0002441484,0.000078811296,0.00004970115,0.000008008672,0.00002926441,0.00004963182,0.00001019612],"category_scores_gemma":[0.000061518134,0.000105600026,0.000048763177,0.00006226416,0.000029168768,0.000038089016,0.0000191165,0.00007272482,0.000007362733],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004291102,0.0046053175,0.9500891,0.00495794,0.00016312649,0.00023570601,0.0018863557,0.0062953304,0.019679258,0.0021175463,0.0012646553,0.0044145724],"study_design_scores_gemma":[0.021934137,0.0022140208,0.12989572,0.0008896193,0.0014847096,0.00000983361,0.00022364644,0.7920146,0.03019977,0.019240094,0.00090172753,0.0009920965],"about_ca_topic_score_codex":0.00016155206,"about_ca_topic_score_gemma":0.000011140455,"teacher_disagreement_score":0.82019335,"about_ca_system_score_codex":0.000029836894,"about_ca_system_score_gemma":0.00012217309,"threshold_uncertainty_score":0.43062443},"labels":[],"label_agreement":null},{"id":"W1991338336","doi":"10.1038/cddis.2013.161","title":"A critical role of toll-like receptor 4 (TLR4) and its’ in vivo ligands in basal radio-resistance","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Atomic Energy (Canada)","funders":"National Natural Science Foundation of China","keywords":"Cell biology; Toll-like receptor; In vivo; Basal (medicine); TLR4; Receptor; Toll; Biology; Signal transduction; Chemistry; Immunology; Innate immune system; Biochemistry; Genetics; Endocrinology","score_opus":0.004343780641449299,"score_gpt":0.2053887655914067,"score_spread":0.2010449849499574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991338336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9729766,0.025917554,0.0000034916154,0.00023436363,0.00008018928,0.00017290532,0.00001706006,0.00000840057,0.0005894394],"genre_scores_gemma":[0.99779457,0.0005159679,0.000015189416,0.000087681714,0.000010036252,0.000035035842,0.000017957851,0.000006146039,0.0015174435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993169,0.00007945709,0.0002112048,0.00016857639,0.000021048563,0.00020285443],"domain_scores_gemma":[0.9996196,0.00014707935,0.000029436467,0.00010468105,0.000030599844,0.00006861075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009632204,0.00009836081,0.00017003683,0.00009993017,0.00003909706,0.000012449903,0.000052710657,0.00009855214,0.0003285173],"category_scores_gemma":[0.00020454085,0.00009034959,0.000026262378,0.000060998016,0.000075505726,0.0001543434,0.00003193784,0.000093096074,0.000043393324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013433357,0.00020401257,0.02892133,0.0001743218,0.000009379046,0.000011155191,0.00062009087,0.000001057523,0.96493995,0.0015445745,0.0016031227,0.00062764756],"study_design_scores_gemma":[0.0051953946,0.00020054048,0.27193558,0.00023189998,0.00005128985,0.000005434773,0.0009463602,0.00026817826,0.70402604,0.0026919842,0.013984379,0.0004629222],"about_ca_topic_score_codex":0.000039608884,"about_ca_topic_score_gemma":0.0000074367504,"teacher_disagreement_score":0.26091394,"about_ca_system_score_codex":0.000011563445,"about_ca_system_score_gemma":0.000059500922,"threshold_uncertainty_score":0.36843494},"labels":[],"label_agreement":null},{"id":"W1992519413","doi":"10.1038/cddis.2011.88","title":"Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Aortic aneurysm repair treatments","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; St. Paul's Hospital; University of British Columbia","funders":"Michael Smith Health Research BC; Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Decorin; Granzyme B; Extracellular matrix; Chemistry; Granzyme; Serine protease; Perforin; Cell biology; Cytotoxic T cell; Proteoglycan; Molecular biology; In vitro; Biochemistry; Protease; Biology","score_opus":0.023438798649930467,"score_gpt":0.23746023824613696,"score_spread":0.2140214395962065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992519413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99684805,0.0015080095,0.000030997,0.00006453397,0.000018368743,0.0003752707,0.000043209482,0.00004150527,0.0010700428],"genre_scores_gemma":[0.9982943,0.00029730366,0.00051293895,0.00027439152,0.000012833549,0.00002539312,0.00004080918,0.000022971015,0.0005190589],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.999005,0.000024130293,0.00026871802,0.00031962543,0.00013479548,0.00024769534],"domain_scores_gemma":[0.9989282,0.000030910654,0.000071903276,0.00025562532,0.000031210544,0.0006821769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053482032,0.00018906483,0.00029279338,0.00010171867,0.000028129803,0.000004817873,0.00004405545,0.00006460443,0.000031901473],"category_scores_gemma":[0.000088527544,0.00015376469,0.00005167973,0.000095553296,0.000093335795,0.00007030428,0.000053634547,0.00009498954,0.0000079095435],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010933155,0.00088142196,0.99305505,0.0005080117,0.000020822145,0.0015531617,0.0005635749,0.0000037923846,0.0017575694,0.00004013527,0.000121710225,0.00040143257],"study_design_scores_gemma":[0.004198634,0.00038237762,0.97146064,0.00009450885,0.00039470033,0.000050355964,0.00010713747,0.020423045,0.0016204639,0.0010612423,0.0000076082565,0.00019927937],"about_ca_topic_score_codex":0.00009436352,"about_ca_topic_score_gemma":0.0000047956037,"teacher_disagreement_score":0.021594407,"about_ca_system_score_codex":0.000016510025,"about_ca_system_score_gemma":0.000091198744,"threshold_uncertainty_score":0.62703425},"labels":[],"label_agreement":null},{"id":"W1995118129","doi":"10.1038/cddis.2014.58","title":"Glycogen synthase kinase 3β represses MYOGENIN function in alveolar rhabdomyosarcoma","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Myogenin; Myogenesis; GSK-3; Alveolar rhabdomyosarcoma; Biology; PAX3; Molecular biology; Rhabdomyosarcoma; Glycogen synthase; Myogenic regulatory factors; Myocyte; Cell biology; Kinase; Phosphorylation; Biochemistry; Transcription factor; Gene","score_opus":0.005552575763065686,"score_gpt":0.21002719782540838,"score_spread":0.20447462206234268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995118129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926671,0.0041413354,0.0007319434,0.00007599727,0.00007774533,0.00013012749,0.000018010625,0.000014151729,0.0021436058],"genre_scores_gemma":[0.99835485,0.0002233635,0.000061461324,0.0008150995,0.00010612522,0.000035375717,0.00020247356,0.000013537824,0.00018770286],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990959,0.000090868285,0.00012993821,0.00040683756,0.000057067726,0.00021934905],"domain_scores_gemma":[0.9992769,0.000019504341,0.00003820992,0.0003270758,0.000022131979,0.00031620424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009484082,0.00014460304,0.000112876165,0.000040653384,0.000080314545,0.000014965182,0.00008515963,0.00009454824,0.000045555917],"category_scores_gemma":[0.00018183542,0.00014023158,0.00006761274,0.000046444373,0.00006468364,0.000006343852,0.00007289992,0.000059280937,0.000014779438],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0065989704,0.0010034281,0.24957554,0.00032812456,0.00005735525,0.00006254787,0.000064812935,0.0003613719,0.720607,0.001122814,0.0054725776,0.014745484],"study_design_scores_gemma":[0.010282813,0.0017489289,0.72382903,0.000084846666,0.00037088536,0.000009823618,0.00026246818,0.0022150944,0.15705556,0.018231926,0.08410217,0.0018064677],"about_ca_topic_score_codex":0.000031216623,"about_ca_topic_score_gemma":0.000011427711,"teacher_disagreement_score":0.5635514,"about_ca_system_score_codex":0.0000032764615,"about_ca_system_score_gemma":0.000051844436,"threshold_uncertainty_score":0.5718478},"labels":[],"label_agreement":null},{"id":"W1998542792","doi":"10.1038/cddis.2014.234","title":"Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cell biology; Cytoplasm; Mitochondrion; Cytochrome c; Membrane; Cytosol; Apoptosis; Chemistry; Bacterial outer membrane; Cell; Inner mitochondrial membrane; Biology; Biophysics; Biochemistry; Gene","score_opus":0.010719211385053619,"score_gpt":0.23426822987520357,"score_spread":0.22354901849014996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998542792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943252,0.0041916547,0.0006087122,0.00017312965,0.000048177808,0.00029229544,0.00012537673,0.000020372261,0.00021505413],"genre_scores_gemma":[0.9967557,0.0015027473,0.00016461812,0.00016430224,0.00013403333,0.00002372979,0.00051156327,0.000024900457,0.0007183752],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989767,0.000050235274,0.00015853178,0.000467153,0.00009860991,0.00024875702],"domain_scores_gemma":[0.99906385,0.000046487323,0.00003660228,0.00020728238,0.000026710426,0.00061909115],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001135262,0.0002106792,0.00018100053,0.000028421862,0.00016870549,0.00004594714,0.00006145528,0.00012501358,0.000008712435],"category_scores_gemma":[0.00008081944,0.00018037474,0.000061216626,0.0000262154,0.00011209685,0.0000068768377,0.000045455676,0.00005239769,8.075643e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004321702,0.00014576709,0.18444808,0.00046837598,0.000052125113,0.0000046145046,0.00028475086,0.00003187306,0.78327024,0.00011629212,0.0006374854,0.030108202],"study_design_scores_gemma":[0.014004947,0.0014423056,0.21622777,0.00010714928,0.00083845056,0.000011683089,0.0006496356,0.012323088,0.61672634,0.0014039841,0.13400416,0.0022605176],"about_ca_topic_score_codex":0.000070109374,"about_ca_topic_score_gemma":0.000029675097,"teacher_disagreement_score":0.16654396,"about_ca_system_score_codex":0.000004697797,"about_ca_system_score_gemma":0.000036594018,"threshold_uncertainty_score":0.7355468},"labels":[],"label_agreement":null},{"id":"W1998979970","doi":"10.1038/cddis.2014.484","title":"The elimination of miR-23a in heat-stressed cells promotes NOXA-induced cell death and is prevented by HSP70","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; University of Guelph","keywords":"Apoptosis; Gene knockdown; Hsp70; Heat shock protein; Cell biology; Heat shock; Hyperthermia; Small hairpin RNA; microRNA; Biology; Molecular biology; Cell culture; Chemistry; Biochemistry; Gene","score_opus":0.009329121348552993,"score_gpt":0.2547771163598254,"score_spread":0.24544799501127243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998979970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995729,0.0026533199,0.00011083765,0.0002543158,0.000019355315,0.00052529643,0.000070387316,0.0000051994866,0.0006322373],"genre_scores_gemma":[0.99828994,0.00049720303,0.000081785955,0.00009067921,0.000031126667,0.000054902943,0.00009163242,0.000017367945,0.0008453595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885285,0.00015057852,0.00019585874,0.00035361623,0.00016314827,0.00028393205],"domain_scores_gemma":[0.99918866,0.000042351985,0.00004119753,0.00031975357,0.000071271694,0.00033673976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023325905,0.00015261727,0.0001307911,0.00003938269,0.0001034681,0.000039266066,0.00013600483,0.000105092826,0.000008614589],"category_scores_gemma":[0.00012606964,0.00011917249,0.000041745127,0.00006143558,0.000058681522,0.0000064872024,0.000106095606,0.00008479093,0.0000026573996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018727907,0.00020318419,0.004699841,0.00019619563,0.0000061707156,0.0000024054902,0.00004693128,0.0000015667396,0.99210936,0.000014110819,0.00056011026,0.0019728723],"study_design_scores_gemma":[0.0009851131,0.00029198133,0.006633313,0.000025116016,0.000017868259,4.2935358e-7,0.000031215925,0.0013314591,0.9877764,0.00009400137,0.0026727696,0.00014036111],"about_ca_topic_score_codex":0.000072378985,"about_ca_topic_score_gemma":0.000011292677,"teacher_disagreement_score":0.004332961,"about_ca_system_score_codex":0.000009862984,"about_ca_system_score_gemma":0.00010417214,"threshold_uncertainty_score":0.4859713},"labels":[],"label_agreement":null},{"id":"W1999720440","doi":"10.1038/cddis.2013.307","title":"Gemcitabine-mediated tumour regression and p53-dependent gene expression: implications for colon and pancreatic cancer therapy","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Fundação para a Ciência e a Tecnologia; Canadian Institutes of Health Research; University of Texas MD Anderson Cancer Center; European Commission; Johns Hopkins University","keywords":"Puma; Gemcitabine; Pancreatic cancer; Apoptosis; Cancer research; Doxorubicin; Programmed cell death; Colorectal cancer; In vivo; Cell cycle; Biology; Cancer; Medicine; Chemotherapy; Internal medicine; Biochemistry","score_opus":0.01769878107150383,"score_gpt":0.26898305750610335,"score_spread":0.2512842764345995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999720440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9524684,0.044002753,0.00030296238,0.0014551886,0.00005465569,0.0013865054,0.00013947545,0.00004477017,0.00014531268],"genre_scores_gemma":[0.9868238,0.010473461,0.00042775337,0.0006794062,0.00009162611,0.00086979417,0.00013000757,0.00002904179,0.00047508552],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991575,0.000023111254,0.00015940706,0.00034967382,0.00009688367,0.00021341933],"domain_scores_gemma":[0.99875516,0.00006429269,0.000067353634,0.00022050187,0.00009307848,0.0007996118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045018955,0.0001668659,0.00020518644,0.000055452834,0.00014622774,0.000036711586,0.000034582506,0.00007405715,0.00006384502],"category_scores_gemma":[0.0000692936,0.00012328911,0.000038556802,0.000054514923,0.000053623593,0.0000665406,0.00003702789,0.000077821525,0.0000035261853],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067469303,0.00015846267,0.055257734,0.0002444361,0.000028843657,0.000016025271,0.00013220937,0.000002663013,0.9331499,0.000030456493,0.0041786986,0.0061259274],"study_design_scores_gemma":[0.0171345,0.0007511891,0.8649863,0.00064982276,0.00066994905,0.00004828119,0.00014261325,0.0017239669,0.10705053,0.0020748426,0.004125465,0.000642534],"about_ca_topic_score_codex":0.00007495412,"about_ca_topic_score_gemma":0.0000029126081,"teacher_disagreement_score":0.82609934,"about_ca_system_score_codex":0.00003211057,"about_ca_system_score_gemma":0.0001500892,"threshold_uncertainty_score":0.5027584},"labels":[],"label_agreement":null},{"id":"W2001103299","doi":"10.1038/cddis.2011.20","title":"Distinct roles for the cellular inhibitors of apoptosis proteins 1 and 2","year":2011,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"","keywords":"Cell biology; Biology; Ubiquitin ligase; Inhibitor of apoptosis; Context (archaeology); Signalling; Ubiquitin; Function (biology); XIAP; Programmed cell death; Signal transduction; Apoptosis; Computational biology; Caspase; Genetics; Gene","score_opus":0.01961154815815379,"score_gpt":0.2470261237832418,"score_spread":0.227414575625088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001103299","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012222213,0.9960444,0.0011774393,0.000005657504,0.00008552447,0.0011435904,0.00023426233,0.000004731979,0.00008216637],"genre_scores_gemma":[0.007948935,0.99027973,0.00016455678,0.000010914561,0.00021559575,0.00022522642,0.00047927917,0.000033420747,0.0006423556],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991691,0.000035199337,0.00023985199,0.00034316586,0.000058887843,0.00015381306],"domain_scores_gemma":[0.9992522,0.00002430109,0.00017790723,0.0002950851,0.000037555008,0.00021295423],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009641832,0.00024523932,0.00035411882,0.00003174094,0.000111038535,0.000020300344,0.00010368953,0.0001725659,0.0000063534094],"category_scores_gemma":[0.000036129044,0.00015046925,0.0002500662,0.000032509644,0.00007877849,0.0000020940672,0.00008089896,0.00005029421,6.263635e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012321067,0.0001529957,0.000060623253,0.020277353,0.00013727382,0.0000014636145,0.000030712275,5.219237e-7,0.0023099328,0.00091708696,0.0007138452,0.975275],"study_design_scores_gemma":[0.00025377746,0.00013205012,0.00003482557,0.0005345054,0.0011565016,7.3898013e-7,0.000010350225,0.00001593043,0.0023968653,0.00029944285,0.99491566,0.00024933496],"about_ca_topic_score_codex":0.000008939866,"about_ca_topic_score_gemma":0.000002054445,"teacher_disagreement_score":0.99420184,"about_ca_system_score_codex":0.0000035863022,"about_ca_system_score_gemma":0.00010432237,"threshold_uncertainty_score":0.6135958},"labels":[],"label_agreement":null},{"id":"W2001642103","doi":"10.1038/cddis.2012.146","title":"A transcriptionally active pRb–E2F1–P/CAF signaling pathway is central to TGFβ-mediated apoptosis","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University","keywords":"E2F1; Transcription factor; Apoptosis; Transforming growth factor; Cell biology; Biology; Cancer research; Promoter; Transforming growth factor beta; Signal transduction; Programmed cell death; Cell cycle; Gene expression; Gene; Genetics","score_opus":0.01089928843241439,"score_gpt":0.22231488431200422,"score_spread":0.21141559587958983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001642103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99407285,0.003437099,0.0008908742,0.00012665312,0.00015279409,0.00029747267,0.00052585313,0.00003344066,0.0004629484],"genre_scores_gemma":[0.9960363,0.000043283042,0.00036814937,0.0020691163,0.00041985261,0.00007114139,0.0005503451,0.00003450989,0.0004072843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985981,0.000054713706,0.00018779824,0.00040350796,0.00019621142,0.00055965834],"domain_scores_gemma":[0.99785167,0.000022364671,0.000050274437,0.00024906863,0.00007086645,0.0017557365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006841712,0.00024083233,0.00014544804,0.000052645024,0.00013708921,0.00004164431,0.00014126171,0.00009824758,0.00017260034],"category_scores_gemma":[0.00011947611,0.00023582211,0.00013639059,0.00007761795,0.00004559037,0.000015409314,0.000058229012,0.00006813802,0.00003914216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009999168,0.0006693611,0.037403233,0.00013065388,0.00007958491,0.0000062441363,0.000643332,0.000062597835,0.95529085,0.000048623773,0.00353046,0.00113512],"study_design_scores_gemma":[0.0013325608,0.00016811938,0.057158645,0.0000497971,0.00019111841,0.0000017458991,0.00019887355,0.000044558907,0.89212763,0.00008536588,0.047962103,0.0006794502],"about_ca_topic_score_codex":0.000009429249,"about_ca_topic_score_gemma":0.0000010382607,"teacher_disagreement_score":0.06316321,"about_ca_system_score_codex":0.00002075745,"about_ca_system_score_gemma":0.00022609383,"threshold_uncertainty_score":0.96165466},"labels":[],"label_agreement":null},{"id":"W2003693067","doi":"10.1038/cddis.2013.413","title":"Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Biomedical Research Council; National Medical Research Council; Medical Research Council; Ministry of Education, India; Ministry of Earth Sciences; National University of Singapore","keywords":"Hsp27; Cell biology; Phosphorylation; p38 mitogen-activated protein kinases; Kinase; Apoptosis; Chemistry; Cytosol; Biology; Heat shock protein; Protein kinase A; Cancer research; Biochemistry; Hsp70; Enzyme","score_opus":0.009773976921053171,"score_gpt":0.21956461348379325,"score_spread":0.20979063656274008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003693067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98835987,0.00021564095,0.010679158,0.00017868412,0.0000056653644,0.00037008827,0.0000324187,0.0000042386864,0.00015422323],"genre_scores_gemma":[0.9993209,0.00011746641,0.00016368431,0.00017910021,0.000014471106,0.000012990532,0.00011957167,0.000012075211,0.000059697286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944663,0.00004223286,0.00011670121,0.00019200087,0.00009657948,0.000105874155],"domain_scores_gemma":[0.9993994,0.0000072813023,0.000039852395,0.00012712806,0.00015607827,0.00027021344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000557456,0.00007630582,0.00008567866,0.00004424601,0.000040585255,0.000010550878,0.000023886287,0.000067292334,0.000049828694],"category_scores_gemma":[0.00010415408,0.00007718008,0.000019400291,0.00008080005,0.00004528342,0.000008267039,0.000050345927,0.000024907988,0.0000048910615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012021025,0.00007890488,0.0024954393,0.00012784022,0.0000057375346,6.6078525e-7,0.00009159628,0.000033682507,0.9953626,0.000015291858,0.00011747568,0.001550562],"study_design_scores_gemma":[0.0005282201,0.00019472366,0.02375517,0.000019292163,0.00001520521,4.7121506e-7,0.000019937028,0.011097436,0.9640473,0.00010829618,0.0001067831,0.00010714416],"about_ca_topic_score_codex":0.000113779286,"about_ca_topic_score_gemma":0.0000054236175,"teacher_disagreement_score":0.03131528,"about_ca_system_score_codex":0.0000059645336,"about_ca_system_score_gemma":0.000043405267,"threshold_uncertainty_score":0.31473124},"labels":[],"label_agreement":null},{"id":"W2005203135","doi":"10.1038/cddis.2013.157","title":"Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Stephen's University","funders":"Science Foundation Ireland; Deutsche Krebshilfe; Royal College of Surgeons in Ireland; Health Research Board","keywords":"Temozolomide; XIAP; Apoptosis; Caspase; Cancer research; Glioblastoma; Cell culture; Caspase 3; Programmed cell death; Tumor progression; Cancer; Biology; Medicine; Internal medicine; Genetics","score_opus":0.0072259401526201415,"score_gpt":0.21658528151915216,"score_spread":0.209359341366532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005203135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967778,0.0011300709,0.0010944431,0.000031386873,0.000064482774,0.00048804836,0.000041482366,0.0000041815592,0.00036813848],"genre_scores_gemma":[0.9993155,0.00010611111,0.00010779712,0.000021126509,0.000060277718,0.000059947393,0.00015468012,0.000008902708,0.00016567527],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992483,0.00003852023,0.00022852971,0.0002026481,0.0001755307,0.000106475134],"domain_scores_gemma":[0.99935293,0.000009675091,0.00012823574,0.0002247002,0.00013215118,0.00015231212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006669899,0.000102137026,0.00014352203,0.000063851825,0.000023445617,0.000005640354,0.00006680454,0.000075152486,0.000015772586],"category_scores_gemma":[0.00007967417,0.00007539407,0.00003257852,0.000071770315,0.000058674974,0.000009128468,0.000054001495,0.000025106452,3.2271163e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002368433,0.0032726594,0.34695053,0.0035296918,0.00009909679,0.000004175297,0.0009277254,0.00056983443,0.6252268,0.0019977717,0.008356376,0.0066968757],"study_design_scores_gemma":[0.016706884,0.0038442265,0.7694025,0.001062788,0.00026981067,0.0000033501792,0.0015406486,0.026265971,0.17566475,0.0024828264,0.0018154739,0.00094078353],"about_ca_topic_score_codex":0.00011768305,"about_ca_topic_score_gemma":0.0000011126835,"teacher_disagreement_score":0.44956204,"about_ca_system_score_codex":0.0000064460933,"about_ca_system_score_gemma":0.000040734354,"threshold_uncertainty_score":0.3074481},"labels":[],"label_agreement":null},{"id":"W2007536208","doi":"10.1038/cddis.2011.25","title":"SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"Royal Society of Canada; Canadian Institutes of Health Research; Royal Society; University of Ottawa; Howard Hughes Medical Institute","keywords":"Apoptosis; Downregulation and upregulation; Flip; Cell biology; Biology; Tumor necrosis factor alpha; Programmed cell death; Caspase 8; Kinase; Repressor; Caspase 2; Caspase; Biochemistry; Transcription factor; Immunology; Gene","score_opus":0.013936386477432425,"score_gpt":0.20655484276495148,"score_spread":0.19261845628751906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007536208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935312,0.0035947158,0.00036430164,0.00003673199,0.00008310864,0.00015231206,0.000023524712,0.000014270939,0.0021998002],"genre_scores_gemma":[0.9971757,0.0006802386,0.00034063432,0.00021818078,0.00005552336,0.000012234992,0.00016649967,0.000018945677,0.001332041],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923414,0.000029045452,0.00012514541,0.00034581518,0.00007318348,0.00019267549],"domain_scores_gemma":[0.99924177,0.000004076457,0.000046660625,0.00022643211,0.000028487815,0.0004525523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059667156,0.00015716135,0.00011009455,0.0000307808,0.00011129177,0.000027812233,0.00006227712,0.00010429895,0.000027457294],"category_scores_gemma":[0.0000115069115,0.0001406311,0.000047230544,0.00003586994,0.000048821097,0.000005205029,0.00007711011,0.000041374908,0.000003870446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002255298,0.00014578758,0.00517685,0.00007109937,0.000023708792,0.000002722538,0.00007549025,5.566523e-7,0.9882832,0.0003498655,0.0016641577,0.0039810436],"study_design_scores_gemma":[0.0029812986,0.00071359734,0.07681948,0.000038665847,0.00034155464,0.000010052473,0.00013072444,0.00060291967,0.8948111,0.005216475,0.017348262,0.0009858474],"about_ca_topic_score_codex":0.000035683213,"about_ca_topic_score_gemma":0.0000015031063,"teacher_disagreement_score":0.09347207,"about_ca_system_score_codex":0.0000040861073,"about_ca_system_score_gemma":0.00003008266,"threshold_uncertainty_score":0.57347697},"labels":[],"label_agreement":null},{"id":"W2008069355","doi":"10.1038/cddis.2015.85","title":"The canonical Wg signaling modulates Bsk-mediated cell death in Drosophila","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Specialized Research Fund for the Doctoral Program of Higher Education of China; National Key Research and Development Program of China; Institute of Genetics; National Natural Science Foundation of China","keywords":"Programmed cell death; Cell biology; Signal transduction; Biology; Transcription factor; Cell fate determination; Cell growth; Apoptosis; Cell signaling; Kinase; Genetics; Gene","score_opus":0.01535434794206328,"score_gpt":0.23302897238576367,"score_spread":0.2176746244437004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008069355","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98656213,0.010932419,0.000049412418,0.00017085373,0.00013723207,0.00015182883,0.00001617897,0.000014151855,0.0019657614],"genre_scores_gemma":[0.9970964,0.0005752434,0.00013808497,0.0003589366,0.00017205662,0.000037566882,0.00015540363,0.000021074868,0.0014452365],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989157,0.0000543111,0.00020161114,0.00034109832,0.00015510521,0.00033220882],"domain_scores_gemma":[0.99908304,0.000032696236,0.000052049352,0.000217151,0.000065504726,0.000549552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021852221,0.0001754238,0.0001197401,0.000027369078,0.00011503122,0.000060679416,0.00017715423,0.000100475765,0.000010057259],"category_scores_gemma":[0.00010150731,0.00013271517,0.000054512042,0.00007073082,0.00006679549,0.0000052749106,0.00010578164,0.00009360202,0.0000145214],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022075663,0.00055724435,0.5853665,0.00017165375,0.000078705656,0.00023842342,0.0005260112,0.002716629,0.39226854,0.00034374843,0.014538221,0.0009867742],"study_design_scores_gemma":[0.020932266,0.00117806,0.14807075,0.00024642478,0.0004491168,0.000021969392,0.0011781803,0.011701753,0.60327005,0.01763656,0.1909954,0.004319442],"about_ca_topic_score_codex":0.00003176629,"about_ca_topic_score_gemma":0.000010859614,"teacher_disagreement_score":0.43729573,"about_ca_system_score_codex":0.000023994644,"about_ca_system_score_gemma":0.00046341246,"threshold_uncertainty_score":0.54119676},"labels":[],"label_agreement":null},{"id":"W2010457667","doi":"10.1038/cddis.2010.21","title":"Histone deacetylase 1 and 2 differentially regulate apoptosis by opposing effects on extracellular signal-regulated kinase 1/2","year":2010,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Cell biology; Biology; HDAC1; Apoptosis; Signal transduction; Histone deacetylase 2; RNA interference; Downregulation and upregulation; ASK1; Transforming growth factor; Cancer research; Kinase; Histone deacetylase; Histone; Protein kinase A; Mitogen-activated protein kinase kinase; Biochemistry; RNA","score_opus":0.004855283115962289,"score_gpt":0.23201512802671037,"score_spread":0.2271598449107481,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010457667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99498063,0.0036729677,0.00022206895,0.00017206215,0.00015376459,0.00041343196,0.000071552124,0.00003468529,0.0002788379],"genre_scores_gemma":[0.99497277,0.00019008863,0.00015787059,0.00016764093,0.00018611761,0.000042914995,0.0003811503,0.000059538957,0.003841887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981752,0.0001199412,0.00022177241,0.0007496192,0.00026393737,0.0004695287],"domain_scores_gemma":[0.99798846,0.000046251327,0.00007469024,0.00051411183,0.000068296955,0.0013082108],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015442586,0.00034240112,0.00022764507,0.00009028268,0.00028343056,0.00009563625,0.00014879463,0.00022587362,0.000053110292],"category_scores_gemma":[0.00013898865,0.00033084038,0.00010000246,0.000076806085,0.00021114241,0.000010057233,0.00013966256,0.00026739878,0.000013063853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051674986,0.00025965332,0.00036003278,0.00014612426,0.000022227194,0.000049478098,0.000022021353,0.000004084034,0.9887668,0.000046932386,0.0053976136,0.0044083167],"study_design_scores_gemma":[0.0016312837,0.0003062092,0.0011404635,0.0000416806,0.0000844656,0.0000058738683,0.0000053340536,0.00048825,0.98930067,0.000056990026,0.006529137,0.00040963903],"about_ca_topic_score_codex":0.000029315468,"about_ca_topic_score_gemma":0.0000055709297,"teacher_disagreement_score":0.0039986777,"about_ca_system_score_codex":0.000020854492,"about_ca_system_score_gemma":0.00011213718,"threshold_uncertainty_score":0.99991435},"labels":[],"label_agreement":null},{"id":"W2012232878","doi":"10.1038/cddis.2012.121","title":"An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity","year":2012,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Huntingtin; Cell biology; Mutant; In vitro; Toxicity; Biology; Chemistry; Computational biology; Biochemistry; Gene","score_opus":0.07816343087470054,"score_gpt":0.3221778088971477,"score_spread":0.24401437802244716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012232878","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10105548,0.89368504,0.00026633227,0.00008861711,0.00011821924,0.003521879,0.00030293048,0.00007468007,0.00088684174],"genre_scores_gemma":[0.7839587,0.21424867,0.000080625985,0.000903223,0.00004836479,0.00059369486,0.000018779518,0.000091793256,0.000056182293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966462,0.0011063075,0.0003087073,0.0010248654,0.0003761309,0.00053774734],"domain_scores_gemma":[0.99811006,0.00020637506,0.0001992827,0.00067975785,0.00003260595,0.0007719369],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019076679,0.00053433696,0.00057365134,0.00015687785,0.0002385531,0.00016408488,0.00044202412,0.00009396892,0.000043335524],"category_scores_gemma":[0.0006308407,0.00036809628,0.00024851947,0.00027363075,0.00010240938,0.000086502405,0.00012684776,0.000359998,0.00004131891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019865962,0.002350161,0.0000037840966,0.00470982,0.000016397165,0.00051783735,0.0002474336,0.000020805332,0.840514,0.08577112,0.000005866683,0.06564413],"study_design_scores_gemma":[0.000782809,0.00028769436,0.00007077732,0.0024321768,0.0011771044,0.000010113699,0.00037212623,0.00026780466,0.9631548,0.020195222,0.009310875,0.0019384866],"about_ca_topic_score_codex":0.000011874896,"about_ca_topic_score_gemma":8.98893e-7,"teacher_disagreement_score":0.6829032,"about_ca_system_score_codex":0.00011564372,"about_ca_system_score_gemma":0.00035675036,"threshold_uncertainty_score":0.9998771},"labels":[],"label_agreement":null},{"id":"W2013513647","doi":"10.1038/cddis.2010.4","title":"Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse","year":2010,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Deutsche Forschungsgemeinschaft","keywords":"Acetylation; Histone deacetylase; Histone; Neurodegeneration; Biology; Retinitis pigmentosa; Histone Acetyltransferases; Retinal degeneration; Programmed cell death; Cell biology; HDAC1; Retinal; Genetics; Biochemistry; Medicine; Apoptosis; Gene","score_opus":0.008793419722910048,"score_gpt":0.25628467690612117,"score_spread":0.24749125718321113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013513647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99688953,0.00010692011,0.00092510326,0.0010307048,0.00004174456,0.00016670833,0.000009431844,0.0000027250308,0.00082710275],"genre_scores_gemma":[0.9974415,0.000045414337,0.00018441811,0.0017716024,0.00008368069,0.000054003467,0.00012556417,0.000005460679,0.00028837947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996155,0.00001582701,0.00006439334,0.00015798639,0.000049287017,0.00009700493],"domain_scores_gemma":[0.9997537,0.00001841942,0.00001406988,0.00009988409,0.000030231127,0.000083678635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054066764,0.000062621075,0.00003387902,0.000015176057,0.00007066349,0.000035305864,0.000053431773,0.00004119662,0.000007370872],"category_scores_gemma":[0.00018850331,0.00004710262,0.000024592759,0.000021833956,0.000026959851,0.000005581125,0.000013756522,0.000039342827,0.0000014767892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053870986,0.00019635884,0.05250737,0.00009931651,0.0000042365095,0.0000032488704,0.0002500063,0.000008809523,0.9294678,0.0032610314,0.012133924,0.0015291858],"study_design_scores_gemma":[0.0032134939,0.00036461957,0.2637578,0.000013926105,0.00007508388,0.0000028556517,0.0006675395,0.0016707219,0.6600176,0.009578353,0.05990748,0.0007305212],"about_ca_topic_score_codex":0.000003192,"about_ca_topic_score_gemma":0.0000042628253,"teacher_disagreement_score":0.26945022,"about_ca_system_score_codex":0.0000010375323,"about_ca_system_score_gemma":0.00004911697,"threshold_uncertainty_score":0.1920789},"labels":[],"label_agreement":null},{"id":"W2016853520","doi":"10.1038/cddis.2014.199","title":"Cell-to-cell variability in cell death: can systems biology help us make sense of it all?","year":2014,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Programmed cell death; Systems biology; Apoptosis; Context (archaeology); Signal transduction; Cell; Biology; Cancer cell; Cell biology; Cell fate determination; Computational biology; Cancer; Genetics; Transcription factor","score_opus":0.018359168658475058,"score_gpt":0.2715037834574991,"score_spread":0.25314461479902406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016853520","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015737602,0.97657144,0.0013590502,0.000020109841,0.00057457364,0.0019009133,0.00084171625,0.000019213428,0.0029753589],"genre_scores_gemma":[0.13495137,0.85886896,0.00026710227,0.00019348328,0.0003267515,0.00014591658,0.0024516347,0.00009125974,0.0027035344],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.99645776,0.0006426057,0.00093106955,0.0011994749,0.00017573763,0.0005933678],"domain_scores_gemma":[0.9973878,0.000099867764,0.0004544077,0.0010363129,0.000111676774,0.0009099243],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00067782553,0.0006853728,0.0013566935,0.00019633981,0.00007400251,0.00004332091,0.0002762339,0.0007765645,0.000021885648],"category_scores_gemma":[0.00008239021,0.0005739811,0.00045636285,0.00015258459,0.000066727516,0.000003114931,0.00027613915,0.00022303636,0.000018205292],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022009616,0.010070065,0.010822481,0.54192555,0.00073508406,0.0009586677,0.00058218313,0.0018827986,0.13967843,0.0029566418,0.015759047,0.27242807],"study_design_scores_gemma":[0.0010881183,0.0003638991,0.00008953212,0.000773174,0.0008616011,0.0000123595955,0.00002115233,0.00031690425,0.0013272753,0.00014130752,0.99405783,0.0009468377],"about_ca_topic_score_codex":0.00024952338,"about_ca_topic_score_gemma":0.000020677528,"teacher_disagreement_score":0.9782988,"about_ca_system_score_codex":0.000058892292,"about_ca_system_score_gemma":0.0005187661,"threshold_uncertainty_score":0.99967116},"labels":[],"label_agreement":null},{"id":"W2018562790","doi":"10.1038/cddis.2013.105","title":"Gap junctional communication promotes apoptosis in a connexin-type-dependent manner","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Rheinische Friedrich-Wilhelms-Universität Bonn; Deutsche Forschungsgemeinschaft","keywords":"HeLa; Apoptosis; Cell biology; Propidium iodide; Connexin; Gap junction; Annexin; Biology; Transfection; Paracrine signalling; Molecular biology; Chemistry; Cell culture; Programmed cell death; Intracellular; Biochemistry","score_opus":0.012844163799989042,"score_gpt":0.2293932561951001,"score_spread":0.21654909239511105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018562790","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946445,0.002316011,0.00003679132,0.0004690838,0.000054722725,0.00021176596,0.0000103301845,0.000008066017,0.0022487054],"genre_scores_gemma":[0.99725735,0.00040247376,0.00013596508,0.00056375656,0.000054348682,0.000052024883,0.00023032082,0.000008695264,0.0012950778],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99940896,0.000055760873,0.00011402491,0.00022644551,0.0000433208,0.00015151197],"domain_scores_gemma":[0.9994655,0.0000119451315,0.0000302083,0.00025065138,0.000053156073,0.00018850085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006200771,0.00009864845,0.000077997596,0.00003325117,0.000056814133,0.000023616476,0.00008493694,0.00007289878,0.0001779645],"category_scores_gemma":[0.00005194971,0.000086234766,0.00003229484,0.000032657746,0.0000504848,0.0000049290597,0.00008981755,0.00005398373,0.00003941382],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010841886,0.0012678257,0.3942939,0.00020203453,0.00007865057,0.000012020348,0.00018329054,0.000055747547,0.56775916,0.004451285,0.017609946,0.013001988],"study_design_scores_gemma":[0.009042964,0.0015103186,0.7568474,0.00010834537,0.00020315927,0.000028472099,0.0007940538,0.002590948,0.097123966,0.026271226,0.10335866,0.0021205125],"about_ca_topic_score_codex":0.0000985216,"about_ca_topic_score_gemma":0.000021603408,"teacher_disagreement_score":0.47063515,"about_ca_system_score_codex":0.0000063940943,"about_ca_system_score_gemma":0.00005301358,"threshold_uncertainty_score":0.3516552},"labels":[],"label_agreement":null},{"id":"W2018647429","doi":"10.1038/cddis.2011.114","title":"HLA-B-associated transcript 3 (Bat3/Scythe) negatively regulates Smad phosphorylation in BMP signaling","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Phosphorylation; SMAD; Signal transduction; Bone morphogenetic protein; Genetics; Gene","score_opus":0.01791083281543225,"score_gpt":0.21351254488478685,"score_spread":0.19560171206935462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018647429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99351484,0.0050169276,0.00019880725,0.000013817468,0.00005830052,0.00020303413,0.000048002174,0.000030396539,0.0009158555],"genre_scores_gemma":[0.99872565,0.00007044074,0.0002494784,0.00017518902,0.00004937412,0.00002904264,0.00022736314,0.000028515722,0.00044495662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998899,0.00007802213,0.00022881282,0.00039978258,0.00011243,0.00028199275],"domain_scores_gemma":[0.99925166,0.000016934613,0.00008106657,0.00020620994,0.000055979028,0.00038814737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000115277355,0.00019838914,0.0001452592,0.00005601426,0.00009337401,0.000026633605,0.00012051402,0.00010965602,0.00007074113],"category_scores_gemma":[0.00014015865,0.00019900069,0.0000878478,0.00008748855,0.000070293296,0.000010795842,0.000033994216,0.00006790564,0.000007527448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018289818,0.001139337,0.25482193,0.00018207298,0.00008492202,0.00009187679,0.001464701,0.0003371829,0.7376686,0.00014405922,0.00053943833,0.0016969161],"study_design_scores_gemma":[0.0021311792,0.00017813925,0.28186014,0.00008972836,0.00012992164,9.458581e-7,0.00019620622,0.00058824883,0.7117957,0.0019133926,0.000582963,0.0005334634],"about_ca_topic_score_codex":0.000054341945,"about_ca_topic_score_gemma":0.000015528309,"teacher_disagreement_score":0.027038211,"about_ca_system_score_codex":0.000017589568,"about_ca_system_score_gemma":0.00014045046,"threshold_uncertainty_score":0.8115012},"labels":[],"label_agreement":null},{"id":"W2018994558","doi":"10.1038/cddis.2012.41","title":"Emerging concepts: linking hypoxic signaling and cancer metabolism","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Lustgarten Foundation; Wellcome Trust; Amgen; Instituto de Salud Carlos III; Damon Runyon Cancer Research Foundation","keywords":"Programmed cell death; Signal transduction; Cell metabolism; Cell biology; Metabolism; Disease; Cancer research; Cell signaling; Biology; Bioinformatics; Apoptosis; Biochemistry; Medicine; Internal medicine","score_opus":0.010973260106785133,"score_gpt":0.26378456367271075,"score_spread":0.2528113035659256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018994558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7201913,0.2783919,0.00021135186,0.000040611987,0.00061929575,0.00009479714,0.000034197394,0.000011098092,0.00040542017],"genre_scores_gemma":[0.9814399,0.013866837,0.00023964541,0.00083557575,0.002938002,0.00003483315,0.00004821386,0.000023278128,0.000573752],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99910444,0.000034443154,0.0001313614,0.00027970766,0.000092086484,0.0003579321],"domain_scores_gemma":[0.99905545,0.000009198976,0.000053552427,0.00016650611,0.000034182794,0.00068109523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109241584,0.00016942115,0.00015427596,0.00003304232,0.00014086964,0.000036543228,0.000062597,0.000070836926,0.000035092413],"category_scores_gemma":[0.000034182252,0.00015885972,0.000064262225,0.000043167795,0.00006180215,0.000013720634,0.00008590081,0.00006561836,0.0000023605332],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002503416,0.00012998068,0.054838426,0.0002563556,0.00008655625,0.0000035334417,0.00061041286,0.000052756564,0.8922389,0.0006219166,0.0019822835,0.048928548],"study_design_scores_gemma":[0.002094276,0.000031427393,0.03354816,0.000055954555,0.00051267893,0.0000071073523,0.00028603003,0.00010544051,0.07961837,0.0003211644,0.8827111,0.0007082491],"about_ca_topic_score_codex":0.00003351307,"about_ca_topic_score_gemma":0.000002481317,"teacher_disagreement_score":0.88072884,"about_ca_system_score_codex":0.000004742312,"about_ca_system_score_gemma":0.00008464236,"threshold_uncertainty_score":0.6478111},"labels":[],"label_agreement":null},{"id":"W2020180698","doi":"10.1038/cddis.2014.529","title":"Heme oxygenase-1 protects against Alzheimer’s amyloid-β1-42-induced toxicity via carbon monoxide production","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Queen's University; Henry Smith Charity; British Heart Foundation; Alzheimer's Society","keywords":"Heme oxygenase; Toxicity; Chemistry; Oxidative stress; Heme; Apoptosis; Biliverdin; AMPK; Pharmacology; Neurotoxicity; Protein kinase A; Cell biology; Kinase; Biochemistry; Biology; Enzyme","score_opus":0.013265405832455045,"score_gpt":0.22296498764379702,"score_spread":0.20969958181134196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020180698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942674,0.00175441,0.0002423989,0.00016536558,0.00020960301,0.000630471,0.000014445823,0.00006041356,0.002655509],"genre_scores_gemma":[0.99744153,0.00014606147,0.00018502997,0.00082068227,0.0006573538,0.00013649494,0.00014586328,0.000050687875,0.0004162803],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981023,0.00012905068,0.00026905478,0.00081953476,0.00020255982,0.00047748556],"domain_scores_gemma":[0.99823505,0.000007861751,0.00010838588,0.0006608851,0.00008443335,0.000903404],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022099516,0.00034628794,0.00022870873,0.00006152652,0.00015509379,0.000045967692,0.00016776762,0.00017743839,0.0000064392307],"category_scores_gemma":[0.00016905116,0.00033284054,0.00013292165,0.00009614744,0.00005864946,0.000010382279,0.000111538655,0.00013755361,0.000012751931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002423976,0.0001695544,0.0017372567,0.00006667916,0.000041247626,0.000013374427,0.00002593499,0.000048554542,0.9915715,0.000013416594,0.0004276591,0.005642439],"study_design_scores_gemma":[0.0008396203,0.00025086012,0.004263383,0.000021641814,0.00010012982,0.0000046741043,0.000034398483,0.0017968826,0.98711365,0.00020635402,0.004807429,0.0005609699],"about_ca_topic_score_codex":0.000056072386,"about_ca_topic_score_gemma":0.000021917804,"teacher_disagreement_score":0.0050814687,"about_ca_system_score_codex":0.000019004932,"about_ca_system_score_gemma":0.00014637919,"threshold_uncertainty_score":0.9999124},"labels":[],"label_agreement":null},{"id":"W2023902449","doi":"10.1038/cddis.2011.83","title":"Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research","keywords":"Programmed cell death; Leishmania; Miltefosine; Apoptosis; Multiple drug resistance; Biology; Drug resistance; Paromomycin; Reactive oxygen species; Microbiology; Leishmaniasis; Cell biology; Immunology; Biochemistry; Antibiotics; Parasite hosting; Visceral leishmaniasis; Aminoglycoside","score_opus":0.03215794081449981,"score_gpt":0.275585902206471,"score_spread":0.2434279613919712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023902449","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9755798,0.0028023284,0.00002713957,0.00084011105,0.000053198983,0.00077976234,0.000026423337,0.000021307158,0.019869901],"genre_scores_gemma":[0.9963059,0.00030514968,0.00064467045,0.0005996029,0.000059777547,0.00008755137,0.000007365854,0.00002155425,0.0019684157],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985468,0.000091056776,0.0002709549,0.00037449825,0.00033822987,0.00037847765],"domain_scores_gemma":[0.99865586,0.00008782236,0.00007270919,0.00046660213,0.00013392698,0.0005830924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025532895,0.00018485409,0.00029315238,0.00011913302,0.00011323584,0.000016765003,0.00016303283,0.000036393823,0.000039133003],"category_scores_gemma":[0.00014798231,0.00013397387,0.00007921582,0.00020442222,0.0000709608,0.00009763694,0.00010220207,0.00015775043,0.000028132548],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0052669053,0.0016731163,0.9337456,0.0014673017,0.000039289935,0.00060890755,0.010328237,0.0000088442985,0.03820273,0.001071805,0.0067894417,0.00079779216],"study_design_scores_gemma":[0.0018565886,0.0001060683,0.977247,0.00019763604,0.000066682675,8.7430175e-7,0.0006580161,0.0000756461,0.018684216,0.0005432848,0.0003968649,0.00016710996],"about_ca_topic_score_codex":0.00031323734,"about_ca_topic_score_gemma":0.00015614748,"teacher_disagreement_score":0.04350138,"about_ca_system_score_codex":0.00005427806,"about_ca_system_score_gemma":0.0001327092,"threshold_uncertainty_score":0.54632956},"labels":[],"label_agreement":null},{"id":"W2024615053","doi":"10.1038/cddis.2012.44","title":"The double life of MULE in preeclamptic and IUGR placentae","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Ubiquitin ligase; Biology; Placenta; Placentation; Hypoxia-inducible factors; Trophoblast; Apoptosis; Ubiquitin; Placental insufficiency; Andrology; Hypoxia (environmental); Cancer research; Cell biology; Fetus; Internal medicine; Chemistry; Medicine; Biochemistry; Pregnancy; Gene; Genetics; Oxygen","score_opus":0.022792750182751165,"score_gpt":0.2590033162446697,"score_spread":0.23621056606191854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024615053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9053836,0.08627145,0.000004084867,0.00028449454,0.00005120534,0.0002359641,0.000005493394,0.000008679431,0.0077550663],"genre_scores_gemma":[0.9967193,0.002431137,0.000035142228,0.00017466604,0.000045109347,0.000021378057,0.0000038651415,0.0000052327496,0.00056419463],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9995143,0.000018899824,0.00010988044,0.0000930004,0.000075551165,0.00018838364],"domain_scores_gemma":[0.99934,0.00008723112,0.000027142998,0.00014013964,0.0000105070285,0.00039495702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000104289276,0.00007592869,0.00012527689,0.000021474683,0.00007250739,0.0000067916603,0.000027483578,0.000023520668,0.000011354337],"category_scores_gemma":[0.00006661931,0.00004850459,0.000022979135,0.000037127575,0.00008074392,0.000057468817,0.000051942254,0.00005763295,0.0000031226677],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010885668,0.00014446118,0.9958392,0.0003186138,0.000014836592,0.0000059706335,0.0005706007,5.0285564e-7,0.00007722517,0.000775974,0.00047961884,0.0006844322],"study_design_scores_gemma":[0.0030076005,0.0000505541,0.99312645,0.00012355548,0.00012300162,0.0000022612858,0.00026179428,0.000069751164,0.0003579551,0.00040480986,0.0023923703,0.00007990087],"about_ca_topic_score_codex":0.000021893831,"about_ca_topic_score_gemma":0.000005703612,"teacher_disagreement_score":0.091335714,"about_ca_system_score_codex":0.000005659419,"about_ca_system_score_gemma":0.00004396802,"threshold_uncertainty_score":0.19779597},"labels":[],"label_agreement":null},{"id":"W2026275021","doi":"10.1038/cddis.2013.259","title":"Reolysin is a novel reovirus-based agent that induces endoplasmic reticular stress-mediated apoptosis in pancreatic cancer","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"National Cancer Institute; Oncolytics Biotech; Max and Minnie Tomerlin Voelcker Fund","keywords":"Unfolded protein response; Pancreatic cancer; Apoptosis; Tunicamycin; Cancer research; Biology; Endoplasmic reticulum; KRAS; Programmed cell death; Oncolytic virus; Cell biology; Cancer; Biochemistry; Colorectal cancer","score_opus":0.012828634079666393,"score_gpt":0.23362389812668954,"score_spread":0.22079526404702315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026275021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99168676,0.006338815,0.00007579741,0.0003854269,0.000079391306,0.00051223085,0.0004516588,0.0000199739,0.00044996708],"genre_scores_gemma":[0.99495494,0.0017912963,0.00014551349,0.001875372,0.000075033204,0.00041561775,0.00042294234,0.000034499586,0.00028477254],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983478,0.000060233146,0.00026581757,0.00064592966,0.00022752819,0.00045266145],"domain_scores_gemma":[0.9984524,0.00003505036,0.00011058364,0.00046107246,0.000064019514,0.00087684405],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000055690416,0.00032155454,0.00025415467,0.00009647047,0.00008924204,0.00008598492,0.0001692329,0.00013494931,0.00026208215],"category_scores_gemma":[0.00012404023,0.00028267084,0.00013448008,0.00011767261,0.00010782905,0.000015427235,0.000089505884,0.00010847624,0.000027029973],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050294213,0.0008437183,0.7060528,0.00049064046,0.00007601088,0.000043440523,0.000095696036,0.000486737,0.28624627,0.000023331017,0.0046569933,0.00048143032],"study_design_scores_gemma":[0.008150372,0.0002695682,0.3056166,0.0004552544,0.0005204958,0.0000024950978,0.0004035112,0.008489801,0.67146665,0.00023720524,0.0028969615,0.001491096],"about_ca_topic_score_codex":0.0006814743,"about_ca_topic_score_gemma":0.000022975197,"teacher_disagreement_score":0.4004362,"about_ca_system_score_codex":0.000028246894,"about_ca_system_score_gemma":0.00026250252,"threshold_uncertainty_score":0.99996257},"labels":[],"label_agreement":null},{"id":"W2030362606","doi":"10.1038/cddis.2013.199","title":"Mitochondrial DNA damage induces apoptosis in senescent cells","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Senescence; DNA damage; Cell biology; Biology; Apoptosis; In vivo; Cancer cell; Thymidine kinase; Mitochondrion; Cancer; Immunology; Herpes simplex virus; DNA; Virus; Biochemistry; Genetics","score_opus":0.02051630969961598,"score_gpt":0.2721327146667747,"score_spread":0.2516164049671587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030362606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932838,0.000543023,0.0000052510054,0.00049218733,0.00011631534,0.00061529735,0.000018408893,0.00002421533,0.004901468],"genre_scores_gemma":[0.9965236,0.0002763257,0.00012368485,0.0005905934,0.00021672367,0.00006601181,0.00002397844,0.000018077628,0.0021609955],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988911,0.000036332873,0.0001779158,0.00030054795,0.00023847075,0.00035562154],"domain_scores_gemma":[0.9985022,0.00003805346,0.000024376946,0.00024884,0.00004954741,0.0011370132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054373628,0.00014398739,0.0002053263,0.00015259368,0.00006264453,0.00007823816,0.00006956232,0.00006899176,0.00090300676],"category_scores_gemma":[0.00004665702,0.00011708872,0.00006768296,0.00014007321,0.000053350137,0.0001122328,0.00007057629,0.00017212698,0.00036319566],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012370785,0.0015286747,0.13279271,0.0007954539,0.000029065897,0.0002553225,0.00045186622,0.0000039413117,0.83135706,0.00013971604,0.020896792,0.010512289],"study_design_scores_gemma":[0.01047008,0.00035875218,0.71589136,0.0002499242,0.00018362659,0.00000330716,0.00050278474,0.0013130534,0.2399822,0.0008949171,0.02941857,0.0007313895],"about_ca_topic_score_codex":0.0005458708,"about_ca_topic_score_gemma":0.000010352381,"teacher_disagreement_score":0.5913749,"about_ca_system_score_codex":0.000043377135,"about_ca_system_score_gemma":0.00020778457,"threshold_uncertainty_score":0.9887291},"labels":[],"label_agreement":null},{"id":"W2032294094","doi":"10.1038/cddis.2011.119","title":"Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Vancouver General Hospital","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Stem Cell Network","keywords":"Cell biology; HES1; NUMB; Biology; Endoplasmic reticulum; Gene knockdown; Unfolded protein response; Insulin; Notch signaling pathway; Cellular differentiation; Embryonic stem cell; Cell growth; Stem cell; Endocrinology; Signal transduction; Internal medicine; Apoptosis; Medicine; Gene","score_opus":0.011698878503483192,"score_gpt":0.21929276878992085,"score_spread":0.20759389028643765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032294094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976045,0.0010037997,0.000008510734,0.00014523475,0.000058167887,0.0006548376,0.000022866494,0.000025557008,0.0004765324],"genre_scores_gemma":[0.9985063,0.00013720788,0.0005101766,0.0003897364,0.000020427948,0.00018460085,0.000024526833,0.000015831372,0.00021121044],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986944,0.00018041384,0.00030604398,0.00039129346,0.00013459257,0.00029321102],"domain_scores_gemma":[0.9989271,0.00017765316,0.000047162324,0.00020418626,0.000033247,0.0006106453],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025874886,0.00018382944,0.00028480843,0.00038857321,0.000037814843,0.000024153398,0.000044010554,0.00008803713,0.00006847581],"category_scores_gemma":[0.00064042566,0.00015462632,0.000025020721,0.0002149412,0.000040090723,0.00013499465,0.000059113834,0.00012802803,0.000009332175],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027562869,0.0004416591,0.69256145,0.00018855733,0.0000013854897,0.00003012242,0.0008837571,0.000007679592,0.3027854,0.0000046919718,0.0001565619,0.00018244001],"study_design_scores_gemma":[0.0031253297,0.0001766761,0.46523622,0.00063396234,0.000017903336,2.8378793e-7,0.000367901,0.00055669766,0.52957094,0.00013245085,0.00003989764,0.00014173292],"about_ca_topic_score_codex":0.000035079633,"about_ca_topic_score_gemma":0.0000070785013,"teacher_disagreement_score":0.22732525,"about_ca_system_score_codex":0.000032801563,"about_ca_system_score_gemma":0.000086944005,"threshold_uncertainty_score":0.6305478},"labels":[],"label_agreement":null},{"id":"W2033376389","doi":"10.1038/cddis.2012.90","title":"14-3-3 Protects against stress-induced apoptosis","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Military College of Canada","funders":"Austrian Science Fund; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Programmed cell death; Autophagy; Cell biology; Biology; Cycloheximide; Apoptosis; Yeast; Mutant; Molecular biology; Biochemistry; Protein biosynthesis; Gene","score_opus":0.012744035548117441,"score_gpt":0.24618012133264278,"score_spread":0.23343608578452535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033376389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99219954,0.001576591,0.00019344238,0.00007679228,0.00018034001,0.0003251529,0.000051557214,0.000020273972,0.0053763115],"genre_scores_gemma":[0.9976315,0.00010262029,0.00021151397,0.00037799194,0.00034678617,0.00013481772,0.00012312806,0.00002006433,0.0010515618],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999265,0.00003553836,0.00010087052,0.00023042205,0.00008152203,0.0002866027],"domain_scores_gemma":[0.998974,0.0000063855996,0.000042691398,0.0002900337,0.00004153216,0.000645358],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000048448874,0.00013836587,0.000076937176,0.000029719886,0.00010901928,0.000030412792,0.00008101816,0.0000764278,0.00003381369],"category_scores_gemma":[0.00012969748,0.00012977293,0.00006622136,0.00003703481,0.000023605535,0.000009921943,0.000083138686,0.00007537263,0.000041211704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016468391,0.00039593608,0.03303726,0.00011309037,0.000032372085,0.0000034350003,0.00005247048,0.000006483452,0.960521,0.00008022731,0.002804637,0.0027884503],"study_design_scores_gemma":[0.00057155994,0.00009324033,0.013974511,0.000026151576,0.000042151645,0.0000016521362,0.00006216164,0.00002093568,0.96433836,0.00007014334,0.02049208,0.00030703214],"about_ca_topic_score_codex":0.000009721496,"about_ca_topic_score_gemma":0.0000012901852,"teacher_disagreement_score":0.01906275,"about_ca_system_score_codex":0.000009362328,"about_ca_system_score_gemma":0.00006207835,"threshold_uncertainty_score":0.52919865},"labels":[],"label_agreement":null},{"id":"W2034854400","doi":"10.1038/cddis.2014.8","title":"Dysfunction of the stress-responsive FOXC1 transcription factor contributes to the earlier-onset glaucoma observed in Axenfeld-Rieger syndrome patients","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Trabecular meshwork; Oxidative stress; Glaucoma; Biology; Transcription factor; Cell biology; Programmed cell death; Gene; Apoptosis; Endocrinology; Internal medicine; Genetics; Medicine; Neuroscience","score_opus":0.011530469681380662,"score_gpt":0.22871300996803579,"score_spread":0.21718254028665512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034854400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976788,0.00040463274,0.0003668403,0.00041429454,0.000080729624,0.00070508686,0.00030576222,0.0000037434104,0.000040079198],"genre_scores_gemma":[0.99920213,0.000025193865,0.000009524349,0.00028671202,0.000021823738,0.00007368835,0.00010493075,0.000010750587,0.00026524448],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99895537,0.00026150828,0.00016206357,0.00023928372,0.00016562891,0.00021612867],"domain_scores_gemma":[0.99926615,0.00003758676,0.000033196942,0.00035455264,0.00010449149,0.00020404467],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014188902,0.00011365595,0.000110618115,0.000039844035,0.00009417707,0.000024305818,0.00016748215,0.00007662875,0.000014213929],"category_scores_gemma":[0.0005304229,0.00007187131,0.000068240886,0.00010293645,0.000053845622,0.000005683864,0.00008539788,0.00008277676,0.0000050970707],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011390505,0.00022305196,0.8969836,0.000088981826,0.00001728952,0.00000244788,0.00007523779,0.000030198362,0.0999734,0.000024449733,0.0004367714,0.0010055053],"study_design_scores_gemma":[0.0010252185,0.0002448519,0.9519695,0.000029258652,0.000015360423,3.6655246e-7,0.00002446098,0.00011222682,0.04372644,0.00006977497,0.0026975323,0.00008501797],"about_ca_topic_score_codex":0.00007267387,"about_ca_topic_score_gemma":0.000089245594,"teacher_disagreement_score":0.056246962,"about_ca_system_score_codex":0.000016343005,"about_ca_system_score_gemma":0.00009701811,"threshold_uncertainty_score":0.29308268},"labels":[],"label_agreement":null},{"id":"W2034921833","doi":"10.1038/cddis.2011.54","title":"Ocular neuroprotection by siRNA targeting caspase-2","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Wellcome Trust","keywords":"Neuroprotection; Small interfering RNA; Optic nerve; Retinal ganglion cell; Caspase 3; Retina; Anterior ischemic optic neuropathy; Caspase 2; RNA interference; Glaucoma; Intravitreal administration; Apoptosis; Optic neuropathy; Biology; Pharmacology; Cell biology; Neuroscience; Biochemistry; RNA; Programmed cell death","score_opus":0.011582346389375208,"score_gpt":0.19780826806325552,"score_spread":0.1862259216738803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034921833","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924179,0.0034213094,0.001003127,0.000015959116,0.0000771559,0.00008960669,0.000020437397,0.000011458153,0.0029430755],"genre_scores_gemma":[0.9980485,0.0003749134,0.00009680996,0.00040561074,0.000084038926,0.000012747323,0.00008737535,0.000011374443,0.0008786158],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994506,0.000024140669,0.00008321122,0.00024728774,0.00004751091,0.00014722919],"domain_scores_gemma":[0.9995312,0.0000014456238,0.000028836956,0.00014820391,0.00002955303,0.00026074497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003698979,0.0000989348,0.000054349402,0.000015120514,0.0000728015,0.000015741725,0.000062252366,0.000046295914,0.000045202614],"category_scores_gemma":[0.000032509164,0.000092276416,0.000046993922,0.000021080188,0.00002468897,0.0000041700787,0.00004454331,0.00004167233,0.000019358258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002703921,0.00011741864,0.011253274,0.0000399934,0.000014110471,0.000046764286,0.00004557769,0.0000032770722,0.97351104,0.000019598443,0.013064859,0.0016136954],"study_design_scores_gemma":[0.0007773622,0.00054312265,0.009879294,0.000013768001,0.00008187608,0.000008000754,0.00011038087,0.00027599948,0.9577133,0.00045471307,0.029660627,0.0004815453],"about_ca_topic_score_codex":0.000049342765,"about_ca_topic_score_gemma":9.821492e-7,"teacher_disagreement_score":0.016595768,"about_ca_system_score_codex":0.0000023319667,"about_ca_system_score_gemma":0.000025503448,"threshold_uncertainty_score":0.3762923},"labels":[],"label_agreement":null},{"id":"W2035460682","doi":"10.1038/cddis.2015.71","title":"In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto; Cancer Research UK","keywords":"Senescence; Biology; Oncogene; Cancer research; Malignant transformation; Cell biology; Melanoma; Anoikis; Multinucleate; Cell cycle; Cancer cell; Phenotype; Cancer; Genetics","score_opus":0.04142768131912537,"score_gpt":0.30513964074827776,"score_spread":0.2637119594291524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035460682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99471503,0.0013912288,0.003123653,0.000057538902,0.00008794898,0.00049541116,0.000033710334,0.000007599657,0.00008786832],"genre_scores_gemma":[0.99655795,0.000045481014,0.001871462,0.0007297571,0.0001289442,0.000100538644,0.00014598899,0.0000151034565,0.00040476574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993693,0.000028817773,0.00012670291,0.00024396776,0.00005985464,0.0001713546],"domain_scores_gemma":[0.99944335,0.000047602938,0.000048969112,0.00010597218,0.000058629154,0.00029547096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013148753,0.000098555014,0.00008494376,0.000022783437,0.000046400557,0.00002720842,0.000053707372,0.00003591061,0.0000026268858],"category_scores_gemma":[0.00033840345,0.00009450688,0.000045209574,0.000023185838,0.0000152509465,0.0000067315696,0.000030009105,0.000019691575,0.0000031486863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023538773,0.000087168846,0.0033657139,0.00016769757,0.0000066627967,0.000009110633,0.00016158895,0.00007779311,0.99145526,0.000015426856,0.0016856502,0.0006140424],"study_design_scores_gemma":[0.0026395412,0.00021140682,0.0004344208,0.000035151726,0.00004001786,0.0000020331415,0.00029674615,0.006532455,0.98581845,0.00021236484,0.0035918525,0.00018557631],"about_ca_topic_score_codex":0.000024596751,"about_ca_topic_score_gemma":0.00000173376,"teacher_disagreement_score":0.0064546615,"about_ca_system_score_codex":0.000013281962,"about_ca_system_score_gemma":0.00010574764,"threshold_uncertainty_score":0.3853879},"labels":[],"label_agreement":null},{"id":"W2035718470","doi":"10.1038/cddis.2013.45","title":"A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fundação de Apoio ao Ensino, Pesquisa e Assistência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo; York University; Yale University","keywords":"Apoptosis; Cell biology; Cytoskeleton; Biology; Actin; Myosin; DNA damage; Molecular biology; Chemistry; DNA; Cell; Biochemistry","score_opus":0.006174036014876504,"score_gpt":0.2085344322116891,"score_spread":0.2023603961968126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035718470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99527454,0.0009809381,0.0014881818,0.0004223901,0.00013727877,0.00045488746,0.000011779835,0.000012689093,0.0012173125],"genre_scores_gemma":[0.9939095,0.0002568127,0.0004477962,0.00080695073,0.000106539206,0.00008318195,0.00007764591,0.000021452719,0.00429014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989967,0.000033376902,0.00017222915,0.00039874465,0.0001008441,0.00029813513],"domain_scores_gemma":[0.9991097,0.0000049874343,0.000038736867,0.00024192905,0.000031349642,0.00057328265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006642301,0.0001794615,0.00013459427,0.00008101218,0.000072106566,0.00006229608,0.00008867801,0.00009518084,0.00005744819],"category_scores_gemma":[0.000012071597,0.00016265709,0.00006519852,0.00007175869,0.000016046657,0.000008670376,0.000088466906,0.000047165573,0.00005885548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006560643,0.00011694666,0.002707443,0.00006614228,0.000009055595,0.0000083351,0.00012756375,0.00017007098,0.99096197,0.00017045546,0.002079079,0.0035173115],"study_design_scores_gemma":[0.001542367,0.00045876077,0.015061865,0.00009498939,0.00006630618,0.000002302284,0.00026390678,0.0016714571,0.95572335,0.0005165342,0.023817165,0.0007809903],"about_ca_topic_score_codex":0.00006139876,"about_ca_topic_score_gemma":0.000011485624,"teacher_disagreement_score":0.035238635,"about_ca_system_score_codex":0.000024114233,"about_ca_system_score_gemma":0.0000480019,"threshold_uncertainty_score":0.66329634},"labels":[],"label_agreement":null},{"id":"W2037995511","doi":"10.1038/cddis.2014.413","title":"Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Queen's University Belfast; Queen's University; Cancer Research UK","keywords":"Camptothecin; Pharmacology; Toxicity; In vivo; Chemistry; Topoisomerase; Apoptosis; Drug; Etoposide; Leukopenia; Systemic administration; In vitro; Medicine; Chemotherapy; Biology; Biochemistry; Internal medicine","score_opus":0.008708747631076303,"score_gpt":0.2541205973619125,"score_spread":0.2454118497308362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037995511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9852924,0.0054387073,0.008877225,0.000009273438,0.00015810477,0.00014792572,0.000020152069,0.00000390596,0.000052307612],"genre_scores_gemma":[0.99671924,0.0029430222,0.00012092283,0.000033921326,0.00011422068,0.0000052208957,0.000020169953,0.0000070447036,0.00003621558],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99943495,0.000061440354,0.00017489484,0.00019307363,0.000051998202,0.000083648716],"domain_scores_gemma":[0.99959993,0.000015922642,0.000109562905,0.00013058384,0.000035431538,0.00010853993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012105412,0.00008894729,0.00015672803,0.000014221897,0.00003841907,0.000008328789,0.00003136343,0.00005870253,0.0000015500492],"category_scores_gemma":[0.00003388064,0.00007345217,0.000040566534,0.00001880845,0.00009088451,0.0000046439363,0.000031123807,0.000025146046,1.04215765e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021908047,0.000057129528,0.0012103848,0.00038555157,0.00001710676,5.210884e-7,0.00003972766,0.000011349193,0.9947263,0.00046903186,0.000009197414,0.00285461],"study_design_scores_gemma":[0.0013440787,0.0006718279,0.011579621,0.00014962259,0.00016985339,0.0000094507695,0.0001016705,0.0009582767,0.9822671,0.0024473695,0.00013007787,0.00017108819],"about_ca_topic_score_codex":0.000016891623,"about_ca_topic_score_gemma":0.0000010976951,"teacher_disagreement_score":0.012459246,"about_ca_system_score_codex":0.0000021539333,"about_ca_system_score_gemma":0.000033533626,"threshold_uncertainty_score":0.29952925},"labels":[],"label_agreement":null},{"id":"W2040519360","doi":"10.1038/cddis.2014.305","title":"miR-17 extends mouse lifespan by inhibiting senescence signaling mediated by MKP7","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Cell biology; Senescence; Biology; Autophagy; Psychological repression; PI3K/AKT/mTOR pathway; Gene silencing; Transcription factor; Carcinogenesis; Signal transduction; Apoptosis; Genetics; Cancer; Gene; Gene expression","score_opus":0.005750907902044736,"score_gpt":0.20256298337551568,"score_spread":0.19681207547347093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040519360","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841203,0.0036410606,0.011320389,0.00014376375,0.00006184807,0.00012280392,0.00012524865,0.00003481295,0.0004297877],"genre_scores_gemma":[0.9951886,0.00031735533,0.00039340882,0.0014804826,0.00017717647,0.000011042962,0.0007062711,0.000036650577,0.0016890411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872595,0.000071534334,0.00019880632,0.00049044675,0.00015130143,0.00036197645],"domain_scores_gemma":[0.99884915,0.000021974323,0.000079266305,0.00027134715,0.000054961467,0.00072326977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015195644,0.0002294616,0.00015328918,0.00002608118,0.00016481664,0.000068305584,0.00015053448,0.00011810535,0.000025491267],"category_scores_gemma":[0.00015347636,0.00023172252,0.00006401539,0.000041206218,0.00008045823,0.0000060003777,0.00010195679,0.00008824108,0.000012520015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041829644,0.00009699344,0.007195698,0.000058559006,0.000009364002,0.0000029969688,0.00007768415,0.000049764894,0.9806536,0.0000065808244,0.01153679,0.00027014813],"study_design_scores_gemma":[0.0012287444,0.0001877789,0.0006568932,0.000024586516,0.00009143508,0.0000031420511,0.00009972065,0.0024023398,0.9668154,0.00012216913,0.027709763,0.00065800926],"about_ca_topic_score_codex":0.00002479002,"about_ca_topic_score_gemma":0.000002401084,"teacher_disagreement_score":0.016172973,"about_ca_system_score_codex":0.0000067549395,"about_ca_system_score_gemma":0.00005655569,"threshold_uncertainty_score":0.944937},"labels":[],"label_agreement":null},{"id":"W2042203222","doi":"10.1038/cddis.2012.59","title":"Endothelial cells regulate p53-dependent apoptosis of neural progenitors after irradiation","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Canadian Cancer Society Research Institute","keywords":"Acid sphingomyelinase; Apoptosis; Cell biology; Biology; Progenitor cell; Neural stem cell; Programmed cell death; Stem cell; Immunology; Ceramide; Biochemistry","score_opus":0.0178128935556307,"score_gpt":0.2201251252824409,"score_spread":0.2023122317268102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042203222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99849564,0.00016283472,0.000049250157,0.000021208964,0.000669138,0.0002714556,0.00014079385,0.00003851239,0.00015113906],"genre_scores_gemma":[0.99902475,0.00007735559,0.000031627573,0.00039076293,0.00016308599,0.00003521745,0.0000018715792,0.000026198739,0.00024910874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873686,0.00011887909,0.00020172779,0.00031938025,0.00027366722,0.00034949908],"domain_scores_gemma":[0.9989087,0.00008448646,0.000094447896,0.00021204056,0.00001752297,0.00068280555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059923645,0.00017207107,0.00014139301,0.000074453856,0.000086754924,0.000034141056,0.00010162743,0.00003544729,0.00006191782],"category_scores_gemma":[0.000081451144,0.00015176146,0.000087595145,0.00008460994,0.00004672379,0.00019823661,0.00006851888,0.000061979365,0.000036154015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002870388,0.00025783692,0.0056783976,0.00006976628,0.0000014332346,0.000016077465,0.000065158965,0.000019248067,0.9930196,0.00026371327,0.000025104515,0.00029666434],"study_design_scores_gemma":[0.00040585533,0.00006877404,0.009538002,0.000005130576,0.000065041626,0.0000036933586,0.0000056166446,0.0004135954,0.9891246,0.000055652,0.00016555654,0.00014850339],"about_ca_topic_score_codex":0.0000030726128,"about_ca_topic_score_gemma":1.07237554e-7,"teacher_disagreement_score":0.003894982,"about_ca_system_score_codex":0.000009187156,"about_ca_system_score_gemma":0.000029276076,"threshold_uncertainty_score":0.61886525},"labels":[],"label_agreement":null},{"id":"W2043178407","doi":"10.1038/cddis.2011.28","title":"Cell-type-specific regulation of raft-associated Akt signaling","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Protein kinase B; Lipid raft; Cell biology; PI3K/AKT/mTOR pathway; Signal transduction; Cell growth; Chemistry; Biology; Cancer research; Biochemistry","score_opus":0.020006960474690916,"score_gpt":0.21624156792864832,"score_spread":0.1962346074539574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043178407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99510914,0.001540428,0.0005073134,0.000010708155,0.000024968016,0.000118487675,0.000019180747,0.000009284158,0.002660467],"genre_scores_gemma":[0.9989468,0.00013283534,0.00026090973,0.00006627448,0.000032354343,0.000007951043,0.00017458432,0.0000065084814,0.00037176666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995465,0.000028144164,0.00010010108,0.00018162394,0.000040146268,0.00010346804],"domain_scores_gemma":[0.99957734,0.000009543654,0.000054401116,0.00014591368,0.000047571968,0.00016523199],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055978468,0.00007597513,0.000071605966,0.000012992569,0.000052361986,0.000005800703,0.000053633048,0.00006578017,0.00005066766],"category_scores_gemma":[0.00002840926,0.00006252221,0.000042297146,0.000044437864,0.000041133153,0.0000016094273,0.000028920378,0.000026771515,0.000005293199],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012731376,0.00020543311,0.008848038,0.000024723402,0.0000061492756,0.0000012291283,0.0000231387,0.00001560491,0.9891127,0.00036473438,0.0008877262,0.00038321855],"study_design_scores_gemma":[0.0010124224,0.00042376065,0.16995218,0.000016922615,0.00006858635,4.896648e-7,0.000043190284,0.0002092666,0.81860703,0.002335665,0.007025309,0.0003051564],"about_ca_topic_score_codex":0.0000060788284,"about_ca_topic_score_gemma":2.4398318e-7,"teacher_disagreement_score":0.17050564,"about_ca_system_score_codex":0.0000026739006,"about_ca_system_score_gemma":0.00002389734,"threshold_uncertainty_score":0.25495818},"labels":[],"label_agreement":null},{"id":"W2047761494","doi":"10.1038/cddis.2014.7","title":"Prostate apoptosis response-4 mediates TGF-β-induced epithelial-to-mesenchymal transition","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Canadian Institutes of Health Research","keywords":"Epithelial–mesenchymal transition; Downregulation and upregulation; Vimentin; Biology; Chromatin immunoprecipitation; Cell biology; SMAD; Transforming growth factor beta; Cell migration; Transforming growth factor; Cancer research; Gene silencing; Signal transduction; Small interfering RNA; Molecular biology; Cell; Cell culture; Transfection; Gene expression; Immunology; Promoter","score_opus":0.00697733518801126,"score_gpt":0.22427626512748133,"score_spread":0.2172989299394701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047761494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977858,0.00043029417,0.0006909969,0.00036752317,0.000099893565,0.00027184605,0.00013060575,0.000037169775,0.00018587908],"genre_scores_gemma":[0.9977456,0.000031890402,0.00029407762,0.0009954908,0.00023830625,0.00006864697,0.00020710062,0.000030470073,0.0003884445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998777,0.00015507668,0.0001726245,0.00045071333,0.0001483981,0.000296215],"domain_scores_gemma":[0.9986182,0.00004146646,0.000043107862,0.00032452907,0.00006165407,0.0009110338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020419733,0.00019677708,0.00013184507,0.00006219976,0.00013097168,0.000047332043,0.000121164994,0.00008084622,0.000022251916],"category_scores_gemma":[0.00037815733,0.00018613001,0.000083749,0.000062930754,0.000041670977,0.0000060127422,0.0000515178,0.00004961226,0.000042060317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00293479,0.00015344132,0.0024026264,0.0000828549,0.000015296537,0.000005245151,0.0001677387,0.00009699744,0.99168324,0.000017482093,0.0008292585,0.0016110064],"study_design_scores_gemma":[0.0015724619,0.00060031784,0.032859955,0.00004335965,0.00012481667,0.0000015439342,0.00006677025,0.000291568,0.9503993,0.0003200934,0.013182665,0.0005371727],"about_ca_topic_score_codex":0.0000074390878,"about_ca_topic_score_gemma":0.0000012046845,"teacher_disagreement_score":0.041283984,"about_ca_system_score_codex":0.0000077050745,"about_ca_system_score_gemma":0.00014974168,"threshold_uncertainty_score":0.75901616},"labels":[],"label_agreement":null},{"id":"W2053647293","doi":"10.1038/cddis.2014.126","title":"Survivin is essential for fertile egg production and female fertility in mice","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Survivin; Biology; Cell biology; Folliculogenesis; Follicular atresia; Oocyte; Follicular phase; Oogenesis; Ovulation; Andrology; Ovarian follicle; Apoptosis; Endocrinology; Embryo; Genetics; Embryogenesis; Medicine","score_opus":0.017668173611796848,"score_gpt":0.2699931337076267,"score_spread":0.25232496009582983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053647293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964463,0.0013794452,0.00022040456,0.0008201505,0.00014452868,0.0005568932,0.000014996368,0.000020284491,0.0003969776],"genre_scores_gemma":[0.9985404,0.000039699982,0.00010455171,0.00025595084,0.00014362927,0.000045211465,0.000031363645,0.000006948888,0.00083221606],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990513,0.00006457476,0.00014324789,0.0005138498,0.000055484943,0.00017159933],"domain_scores_gemma":[0.99935555,0.000040785373,0.000029149707,0.00023920812,0.000060900657,0.00027440922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003401427,0.00010700167,0.00018059443,0.000036566784,0.000077405275,0.000009239371,0.000025408175,0.00006049117,0.000023906246],"category_scores_gemma":[0.0007699559,0.000088776746,0.000039547227,0.00004685536,0.0001082379,0.000060949635,0.000024884099,0.00006947049,0.0000035254245],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010283232,0.0004238076,0.9750852,0.0005776176,0.000009446335,0.000002100932,0.000201584,4.7956087e-7,0.010621573,0.00003058147,0.00030836396,0.0024560222],"study_design_scores_gemma":[0.0008165739,0.00010317398,0.9847719,0.000020165766,0.00007050995,0.0000014153653,0.000033775028,0.00031735186,0.011592014,0.0014840827,0.0006995065,0.000089512345],"about_ca_topic_score_codex":0.000039035123,"about_ca_topic_score_gemma":0.000013879769,"teacher_disagreement_score":0.009686727,"about_ca_system_score_codex":0.000013001487,"about_ca_system_score_gemma":0.000051221796,"threshold_uncertainty_score":0.36202106},"labels":[],"label_agreement":null},{"id":"W2057976490","doi":"10.1038/cddis.2010.74","title":"Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid β-peptide-independent neuronal degeneration in primary human neuron cultures.","year":2010,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; McGill University; Canadian Institutes of Health Research; Université Laval; University of Washington","keywords":"Amyloid (mycology); Amyloid precursor protein; Mutant; P3 peptide; Peptide; Biochemistry of Alzheimer's disease; Neuronal degeneration; Neuron; Biology; Degeneration (medical); Cell biology; Chemistry; Biochemistry; Neuroscience; Alzheimer's disease; Pathology; Medicine; Gene","score_opus":0.019261147557565368,"score_gpt":0.2779096909232069,"score_spread":0.2586485433656415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057976490","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942205,0.0015074327,0.0000055213277,0.00017051965,0.0001383298,0.002105527,0.00035167614,0.00008727028,0.0014132245],"genre_scores_gemma":[0.99688154,0.00012364225,0.00008117809,0.0003564202,0.00031008216,0.00034088007,0.00070977345,0.0000605571,0.0011359317],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9971154,0.00013139908,0.00039493977,0.00083581154,0.0008317109,0.0006907736],"domain_scores_gemma":[0.99696356,0.000027218273,0.000099964396,0.00052156835,0.00011431546,0.0022733996],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013784574,0.0004236808,0.00035808925,0.00019885901,0.0002696625,0.00011355018,0.00014800475,0.00014772348,0.000164775],"category_scores_gemma":[0.00010067779,0.0003603073,0.00014080953,0.00012712124,0.00012612317,0.0002503285,0.00012816646,0.00058216136,0.000085636304],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0064697554,0.0076157628,0.44553807,0.0008707056,0.0005993697,0.0130434465,0.00024261483,0.000022935534,0.5220188,0.00026177283,0.0011132889,0.0022035064],"study_design_scores_gemma":[0.009273851,0.0006440377,0.96103185,0.00008868982,0.0006913684,0.000060520266,0.00004656525,0.00022625002,0.026945524,0.00032265057,0.00014713283,0.0005215647],"about_ca_topic_score_codex":0.0002460673,"about_ca_topic_score_gemma":0.00023585754,"teacher_disagreement_score":0.51549375,"about_ca_system_score_codex":0.00012434588,"about_ca_system_score_gemma":0.0007222151,"threshold_uncertainty_score":0.9998849},"labels":[],"label_agreement":null},{"id":"W2058765546","doi":"10.1038/cddis.2012.210","title":"Vorinostat-induced autophagy switches from a death-promoting to a cytoprotective signal to drive acquired resistance","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Vorinostat; Autophagy; Biology; Cell biology; Programmed cell death; Histone deacetylase; Cancer research; Gene knockdown; Cell culture; Apoptosis; Histone; Biochemistry; Genetics","score_opus":0.011827109881281031,"score_gpt":0.24806124261507756,"score_spread":0.23623413273379654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058765546","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958061,0.0006517152,0.001000892,0.00041872385,0.00005525947,0.0010688597,0.00011099166,0.00003139196,0.0008560403],"genre_scores_gemma":[0.995071,0.000009341106,0.0015256894,0.00054389687,0.000279287,0.0004138562,0.00007242278,0.00003974237,0.002044745],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981223,0.000085400876,0.000217435,0.00080687326,0.00025314782,0.0005148622],"domain_scores_gemma":[0.99777734,0.00003137322,0.000050713687,0.00045816775,0.00015283612,0.0015295651],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009956411,0.00025708767,0.00020106461,0.00008338954,0.00019592278,0.00010111462,0.0002221862,0.000112041875,0.00007771672],"category_scores_gemma":[0.00030406314,0.0002545571,0.000086829525,0.00013425271,0.000034761368,0.000012832834,0.00026533214,0.00009242538,0.00020349909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044036694,0.000105669584,0.0020054416,0.000038587386,0.000022964454,0.00005161174,0.00046038738,0.000007541439,0.9933168,0.000016951291,0.0019063856,0.0016272687],"study_design_scores_gemma":[0.0007549768,0.00032925652,0.028740082,0.000058239144,0.000026023554,9.578139e-7,0.00011683337,0.00012750164,0.96681577,0.0004655863,0.0021522401,0.0004125413],"about_ca_topic_score_codex":0.00038995838,"about_ca_topic_score_gemma":0.000056558667,"teacher_disagreement_score":0.02673464,"about_ca_system_score_codex":0.000051953095,"about_ca_system_score_gemma":0.00024776984,"threshold_uncertainty_score":0.99999064},"labels":[],"label_agreement":null},{"id":"W2058851119","doi":"10.1038/cddis.2013.342","title":"Lithium chloride attenuates cell death in oculopharyngeal muscular dystrophy by perturbing Wnt/β-catenin pathway","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Muscular Dystrophy Association","keywords":"Wnt signaling pathway; Oculopharyngeal muscular dystrophy; Effector; C2C12; Cancer research; Biology; GSK-3; Cell biology; Muscular dystrophy; Catenin; Beta-catenin; Signal transduction; Myocyte; Endocrinology; Chemistry; Genetics; Myogenesis","score_opus":0.005497738824645959,"score_gpt":0.1959824520406674,"score_spread":0.19048471321602142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058851119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908911,0.0066346196,0.000069974994,0.0001834263,0.000088561326,0.0003055963,0.00005098991,0.000018985485,0.0017567624],"genre_scores_gemma":[0.99662524,0.000521801,0.00007327897,0.0008712446,0.00011529642,0.00011045035,0.00050030183,0.000029318646,0.0011530478],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858433,0.00006860868,0.000214197,0.0005836087,0.000098229524,0.0004510445],"domain_scores_gemma":[0.9990673,0.00001610253,0.00006092387,0.00026444448,0.000046356905,0.000544868],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000066656205,0.00027889945,0.00020964518,0.00004859017,0.00012186824,0.000044257285,0.00017363939,0.00015664582,0.000071030234],"category_scores_gemma":[0.000045788853,0.00025102348,0.000119566495,0.00006193572,0.00007969003,0.000017380373,0.00011989358,0.00010956688,0.000051255134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005321688,0.00045301326,0.052489184,0.00021269039,0.000024868637,0.000041416322,0.00009043939,0.00006309546,0.9411456,0.000060097875,0.0042430083,0.00064441527],"study_design_scores_gemma":[0.009810983,0.0011502801,0.25461775,0.00009450929,0.00021418618,0.0000078557605,0.00066031126,0.002310944,0.7084544,0.0048872544,0.015171762,0.0026198088],"about_ca_topic_score_codex":0.00018439224,"about_ca_topic_score_gemma":0.000003980546,"teacher_disagreement_score":0.23269124,"about_ca_system_score_codex":0.000010363256,"about_ca_system_score_gemma":0.000098521385,"threshold_uncertainty_score":0.9999942},"labels":[],"label_agreement":null},{"id":"W2060278507","doi":"10.1038/cddis.2014.182","title":"Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Natural Compounds in Disease Treatment","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Canadian Institutes of Health Research; Ministère du Développement Économique, de l’Innovation et de l’Exportation","keywords":"Celastrol; Proteostasis; Auranofin; Programmed cell death; Cancer research; Heat shock protein; Autophagy; Biology; Cell biology; Reactive oxygen species; Hsp90; Apoptosis; Immunology; Biochemistry","score_opus":0.006348902493998499,"score_gpt":0.23156898575532683,"score_spread":0.22522008326132834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060278507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99521655,0.00056826265,0.00022388154,0.0006155621,0.000037010508,0.0019153362,0.000068223344,0.00011566179,0.0012395178],"genre_scores_gemma":[0.9945853,0.000004308426,0.0030833047,0.00058158353,0.00018086078,0.00032017427,0.000036403086,0.000050782888,0.0011572796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815446,0.00006839681,0.0002362607,0.00066328497,0.00038595768,0.00049166713],"domain_scores_gemma":[0.9963834,0.00004385244,0.00004843354,0.00044767783,0.000116097726,0.0029605187],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007843852,0.00039011257,0.00038177165,0.0001612436,0.00021503094,0.00008429147,0.0000808187,0.000072436196,0.00006840519],"category_scores_gemma":[0.000109029344,0.00028129187,0.00007316558,0.00015322269,0.00011356343,0.00008179432,0.00010876599,0.00016900928,0.000031393873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.055479106,0.009544307,0.06051675,0.007037655,0.00063669035,0.0068560806,0.000843685,0.000121165496,0.8303555,0.003269418,0.011164634,0.014174984],"study_design_scores_gemma":[0.048719652,0.037887417,0.26925376,0.0040317406,0.0051207994,0.0001786068,0.00024256595,0.0022044275,0.59428895,0.0034075018,0.030259212,0.0044053835],"about_ca_topic_score_codex":0.000020140613,"about_ca_topic_score_gemma":0.000006955989,"teacher_disagreement_score":0.2360666,"about_ca_system_score_codex":0.00008057988,"about_ca_system_score_gemma":0.00013507491,"threshold_uncertainty_score":0.99996394},"labels":[],"label_agreement":null},{"id":"W2065179135","doi":"10.1038/cddis.2011.104","title":"OGX-427 inhibits tumor progression and enhances gemcitabine chemotherapy in pancreatic cancer","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Vancouver General Hospital","funders":"Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Association pour la Recherche sur les Tumeurs de la Prostate; Institut National Du Cancer; Association pour la Recherche sur le Cancer","keywords":"Gemcitabine; Hsp27; Cancer research; Pancreatic cancer; Gene knockdown; Cancer; Metastasis; Heat shock protein; Apoptosis; Chemotherapy; Cancer cell; Internal medicine; Biology; Medicine; Oncology; Hsp70","score_opus":0.015144607451428323,"score_gpt":0.2858418488578854,"score_spread":0.27069724140645707,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065179135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845709,0.013942805,0.00002790154,0.000084001236,0.000015822829,0.0003614359,0.000013392064,0.0000072081775,0.0009764998],"genre_scores_gemma":[0.9958881,0.002997158,0.00025086093,0.00020035704,0.000059882623,0.00015494158,0.000017806102,0.000015599593,0.00041530796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918646,0.00004176436,0.00011230052,0.00032036897,0.00009329993,0.00024579847],"domain_scores_gemma":[0.9993988,0.00000497541,0.000023952125,0.00016263034,0.00002917267,0.00038045133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000889865,0.00012254615,0.00011000072,0.000041033123,0.000049863243,0.0000172783,0.00006475312,0.000048462964,0.000055680874],"category_scores_gemma":[0.000048109727,0.0000998375,0.000021504642,0.000056065535,0.00007205795,0.0000062574995,0.00007341786,0.000059447706,0.0000023606895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011956133,0.00031278364,0.3081661,0.0003636348,0.000014095098,0.000059036185,0.00022495555,6.950351e-7,0.6716949,0.00002619274,0.00019157691,0.017750453],"study_design_scores_gemma":[0.0017062761,0.00029367962,0.14971094,0.00011113789,0.000016003592,0.000003007745,0.00004252283,0.00013961719,0.8451892,0.00032739135,0.0022019746,0.00025822732],"about_ca_topic_score_codex":0.00006863505,"about_ca_topic_score_gemma":0.000021115251,"teacher_disagreement_score":0.17349437,"about_ca_system_score_codex":0.00000804611,"about_ca_system_score_gemma":0.00012895546,"threshold_uncertainty_score":0.40712553},"labels":[],"label_agreement":null},{"id":"W2067020827","doi":"10.1038/cddis.2012.61","title":"Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Canadian Institutes of Health Research; Manitoba Health Research Council; Natural Sciences and Engineering Research Council of Canada; GlaxoSmithKline","keywords":"Autophagy; Unfolded protein response; Cell biology; Programmed cell death; Apoptosis; Endoplasmic reticulum; Chemistry; Simvastatin; Protein kinase A; Biology; Kinase; Pharmacology; Biochemistry","score_opus":0.018739141129871063,"score_gpt":0.27885408769905295,"score_spread":0.2601149465691819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067020827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99065375,0.0072852946,0.000006165709,0.000048663136,0.000093703995,0.00044111532,0.00009687072,0.00003715464,0.0013372579],"genre_scores_gemma":[0.9986143,0.00031023173,0.000053686028,0.00024421062,0.00029123458,0.000019041761,0.00011421154,0.0000292486,0.00032383378],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987016,0.00006711874,0.00031745769,0.00029802942,0.00022582956,0.00038998105],"domain_scores_gemma":[0.9984702,0.000053276948,0.000102812926,0.00025338455,0.00003878222,0.0010815792],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118353426,0.00023578755,0.000344536,0.00014859419,0.000088249675,0.00001746178,0.00004771048,0.000115041694,0.00014946006],"category_scores_gemma":[0.000029496385,0.00020825594,0.00013145505,0.00009289829,0.000059591912,0.00020463149,0.00005520196,0.00014304544,0.000008762931],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035034472,0.0033064508,0.6110281,0.002734403,0.00014462249,0.0002984208,0.0015570046,0.000015517719,0.37154296,0.0041144183,0.0004241247,0.0013305522],"study_design_scores_gemma":[0.01034197,0.00037311603,0.5046615,0.0002717672,0.00051952654,0.0000060960274,0.00013131503,0.00014328532,0.48145318,0.0015986717,0.000112868496,0.00038670484],"about_ca_topic_score_codex":0.00010428256,"about_ca_topic_score_gemma":0.0000019745412,"teacher_disagreement_score":0.10991021,"about_ca_system_score_codex":0.000030744093,"about_ca_system_score_gemma":0.00011937332,"threshold_uncertainty_score":0.84924304},"labels":[],"label_agreement":null},{"id":"W2072079848","doi":"10.1038/cddis.2012.58","title":"Intrinsic regulation of hemangioma involution by platelet-derived growth factor","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Vascular Malformations and Hemangiomas","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; London Health Sciences Centre; Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Platelet-derived growth factor receptor; Adipogenesis; Biology; Cell biology; Involution (esoterism); Platelet-derived growth factor; Growth factor; Stem cell; Tyrosine phosphorylation; Signal transduction; Endocrinology; Internal medicine; Receptor; Cancer research; Biochemistry; Medicine; Mesenchymal stem cell; Neuroscience","score_opus":0.012834475803690449,"score_gpt":0.22093004285283846,"score_spread":0.208095567049148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072079848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936549,0.0045514223,0.00066900393,0.000110107736,0.000038929444,0.0002145722,0.000025856874,0.000027887747,0.0007073047],"genre_scores_gemma":[0.99914205,0.00009999537,0.0002165423,0.00008973278,0.00006948223,0.000008554645,0.00020876277,0.000009201017,0.00015569301],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9994657,0.000013374427,0.00014926906,0.000089483474,0.00012497367,0.00015719309],"domain_scores_gemma":[0.99929136,0.000010702741,0.00005644712,0.00013542414,0.000060704817,0.00044533965],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045830584,0.00008660728,0.00012933071,0.0000791711,0.000053475516,0.00000671524,0.000020244055,0.00004458589,0.00008772818],"category_scores_gemma":[0.000041919193,0.0000739217,0.00007646511,0.00008123877,0.000028399363,0.0001852289,0.0000188377,0.000033232205,0.00001737335],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084825134,0.0015848869,0.7776162,0.002414545,0.00015282637,0.0000152279035,0.0016411473,0.0000018359553,0.18380825,0.009564916,0.013169849,0.009182077],"study_design_scores_gemma":[0.0014625773,0.00006151318,0.9688667,0.000037147565,0.00014956514,0.000008315653,0.00005059019,0.00023086721,0.027320217,0.0003966343,0.0012962266,0.000119612436],"about_ca_topic_score_codex":0.0000139938265,"about_ca_topic_score_gemma":2.279533e-7,"teacher_disagreement_score":0.19125055,"about_ca_system_score_codex":0.000021502912,"about_ca_system_score_gemma":0.00003351656,"threshold_uncertainty_score":0.30144393},"labels":[],"label_agreement":null},{"id":"W2072772509","doi":"10.1038/cddis.2011.105","title":"Temporal blastemal cell gene expression analysis in the kidney reveals new Wnt and related signaling pathway genes to be essential for Wilms' tumor onset","year":2011,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stollery Children's Hospital","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Wnt signaling pathway; Biology; Blastema; Wilms' tumor; Cellular differentiation; Stromal cell; Gene; Laser capture microdissection; Cell biology; Gene expression; Gene expression profiling; Microarray analysis techniques; Signal transduction; Microarray; Cancer research; Genetics; Regeneration (biology)","score_opus":0.011004729940367459,"score_gpt":0.21970150242174458,"score_spread":0.2086967724813771,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072772509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951414,0.0035013743,0.0005849717,0.00010068385,0.00005208819,0.000330239,0.00009798068,0.000005569202,0.00018569443],"genre_scores_gemma":[0.997607,0.00016373604,0.0005233768,0.00069447636,0.00007984244,0.000034507055,0.0002398335,0.000012575734,0.00064464135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906325,0.000067118664,0.00020601811,0.00036566373,0.00008753087,0.00021041774],"domain_scores_gemma":[0.99911857,0.000011345423,0.0000728418,0.00018689407,0.000025975267,0.00058438315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013074343,0.00015402863,0.00015796232,0.000064675194,0.000094834686,0.00002824337,0.00010874924,0.00008400816,0.000017217182],"category_scores_gemma":[0.00002995098,0.000103437305,0.00011771532,0.00012510341,0.000033254415,0.000005554998,0.000056399935,0.000055520813,0.0000010004163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001076684,0.00013400645,0.022489345,0.00013945068,0.000087445485,0.00007488522,0.0005460162,0.0002368913,0.97267205,0.0000094949655,0.0023454572,0.00018830699],"study_design_scores_gemma":[0.002104279,0.00038702367,0.006181011,0.000067742505,0.0007280934,0.000007992161,0.00035302245,0.00026071657,0.98728293,0.00049289525,0.0016929305,0.00044137108],"about_ca_topic_score_codex":0.00006423036,"about_ca_topic_score_gemma":0.0000056123113,"teacher_disagreement_score":0.016308334,"about_ca_system_score_codex":0.000004844979,"about_ca_system_score_gemma":0.00014873888,"threshold_uncertainty_score":0.42180508},"labels":[],"label_agreement":null},{"id":"W2073834135","doi":"10.1038/cddis.2014.349","title":"Sialidase NEU4 is involved in glioblastoma stem cell survival","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Associazione Italiana per la Ricerca sul Cancro","keywords":"Neurosphere; Stem cell; Wnt signaling pathway; Cancer research; Biology; Cancer stem cell; Homeobox protein NANOG; Neural stem cell; Stem cell marker; Signal transduction; Cellular differentiation; Cell biology; Induced pluripotent stem cell; Adult stem cell; Embryonic stem cell; Biochemistry","score_opus":0.00667665834418261,"score_gpt":0.20702293308551964,"score_spread":0.20034627474133704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073834135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970306,0.0009836246,0.00042989754,0.000062414285,0.00009798182,0.0001377213,0.00004587043,0.000010159603,0.00120172],"genre_scores_gemma":[0.99697477,0.00026915895,0.000037676407,0.0009195949,0.00012818933,0.000013567862,0.000049070786,0.000020283502,0.0015876944],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909765,0.00006191187,0.00015074546,0.00036489652,0.00007515564,0.00024964352],"domain_scores_gemma":[0.99919766,0.000010395661,0.000041521933,0.00030605588,0.000026606558,0.00041775833],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008845752,0.00016428722,0.00013213862,0.000040148392,0.000049295646,0.000035313195,0.00010990456,0.00009613811,0.000015313453],"category_scores_gemma":[0.000012649254,0.00014438247,0.00007097872,0.000049834583,0.000034482353,0.0000040332543,0.00009513486,0.000061034938,0.000017024813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013609491,0.0008639385,0.20773917,0.0005659135,0.000024977737,0.00007370094,0.00023820858,0.00008529927,0.7747965,0.00036403796,0.0075515066,0.006335784],"study_design_scores_gemma":[0.008377899,0.0010636109,0.024803657,0.00007319853,0.00018333597,0.0000041329968,0.00040869004,0.0059078373,0.78587615,0.0008164887,0.170804,0.0016809921],"about_ca_topic_score_codex":0.000021010052,"about_ca_topic_score_gemma":0.000037243764,"teacher_disagreement_score":0.18293552,"about_ca_system_score_codex":0.0000068587015,"about_ca_system_score_gemma":0.00006860667,"threshold_uncertainty_score":0.5887746},"labels":[],"label_agreement":null},{"id":"W2074868901","doi":"10.1038/cddis.2013.100","title":"BNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomas","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; Manitoba Health Research Council; CancerCare Manitoba Foundation; U.S. Department of Defense","keywords":"Glioma; Temozolomide; Programmed cell death; Apoptosis; Cancer research; Gene knockdown; Biology; Repressor; Molecular biology; Gene expression; Gene; Genetics","score_opus":0.012465363948141465,"score_gpt":0.23295075469422075,"score_spread":0.22048539074607929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074868901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951154,0.002758788,0.00019778093,0.000040898438,0.000084075175,0.00048743258,0.000032497323,0.00000957153,0.0012735334],"genre_scores_gemma":[0.9966445,0.00091130007,0.0006585115,0.00007767015,0.00007315507,0.00005815789,0.00020192514,0.000023195544,0.0013515586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998748,0.000071518196,0.0002691919,0.0004909015,0.00016881476,0.000251564],"domain_scores_gemma":[0.99911326,0.000012748215,0.00009774807,0.0002674743,0.000052508483,0.00045623296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009843541,0.00021280728,0.00018586246,0.00007837898,0.000074144555,0.00003201852,0.00009561539,0.00017744894,0.000114930575],"category_scores_gemma":[0.0000258126,0.00018750224,0.00008379051,0.000053457497,0.000029147026,0.000023289704,0.000051599836,0.00007279911,0.0000057252487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024561,0.00025917534,0.008042017,0.00013974246,0.00000726343,0.0000059483946,0.00009478163,0.00001641633,0.9899961,0.00018017959,0.00011959819,0.0008932004],"study_design_scores_gemma":[0.0027424817,0.00034446103,0.13971531,0.00009997091,0.00006126516,0.000005379589,0.00007494107,0.0003412324,0.8520088,0.002438785,0.001787444,0.0003798773],"about_ca_topic_score_codex":0.0000643324,"about_ca_topic_score_gemma":0.0000029079104,"teacher_disagreement_score":0.13798723,"about_ca_system_score_codex":0.000009939991,"about_ca_system_score_gemma":0.000078902645,"threshold_uncertainty_score":0.76461196},"labels":[],"label_agreement":null},{"id":"W2079961239","doi":"10.1038/cddis.2012.137","title":"CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut Gustave-Roussy; Institute of Cancer Research; Institut National Du Cancer; Fondation de France; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"CXCR4; Myeloid leukemia; Leukemia; Chemokine; Chemokine receptor; Cancer research; CXC chemokine receptors; Haematopoiesis; Bone marrow; Biology; In vivo; Jurkat cells; Immunology; Cell biology; T cell; Stem cell; Inflammation; Immune system","score_opus":0.0152665050460506,"score_gpt":0.2555407786304294,"score_spread":0.2402742735843788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079961239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957636,0.0013355622,0.00033365778,0.00004890144,0.00007405223,0.00029043356,0.00003204667,0.000063939704,0.002057779],"genre_scores_gemma":[0.9958313,0.00015410807,0.0005849764,0.00032594372,0.00031241812,0.000023063698,0.000059331745,0.000049329734,0.0026595404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985198,0.000031964108,0.00029006423,0.00035636738,0.00023051286,0.0005712843],"domain_scores_gemma":[0.9984439,0.000030113157,0.000081254344,0.00021663563,0.00005353914,0.0011745369],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015641328,0.00027559538,0.00033079175,0.00015767686,0.00015813418,0.000044301694,0.00006758288,0.00011205755,0.000042336094],"category_scores_gemma":[0.000029015715,0.00024790558,0.00011820066,0.00013485072,0.000054030566,0.00023123105,0.00007571012,0.00026729642,0.000015220307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003994462,0.0004551911,0.068477005,0.00032882008,0.00002900886,0.00005509554,0.0012165273,0.00031564673,0.92601055,0.000051712777,0.0018398017,0.0008212151],"study_design_scores_gemma":[0.005120865,0.0001361825,0.013965644,0.00032121397,0.0006306381,0.000009129542,0.00027497043,0.032312267,0.94529027,0.00031339485,0.0008332432,0.0007921648],"about_ca_topic_score_codex":0.000045938472,"about_ca_topic_score_gemma":0.0000013164829,"teacher_disagreement_score":0.054511357,"about_ca_system_score_codex":0.0002049235,"about_ca_system_score_gemma":0.00022404244,"threshold_uncertainty_score":0.9999973},"labels":[],"label_agreement":null},{"id":"W2080681527","doi":"10.1038/cddis.2012.149","title":"Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; Medical Research Council; Leukemia and Lymphoma Society; Canadian Institutes of Health Research; Susan G. Komen; Cancer Therapeutics Cooperative Research Centre","keywords":"Translation (biology); Programmed cell death; Homoharringtonine; Apoptosis; Cytotoxicity; Biology; Cancer research; Myeloid leukemia; Clonogenic assay; Cytotoxic T cell; Cell biology; In vitro; Biochemistry; Messenger RNA; Gene","score_opus":0.009288568604410586,"score_gpt":0.21436518796358348,"score_spread":0.2050766193591729,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080681527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98108894,0.011746535,0.0059440862,0.00010788001,0.0002620787,0.0004063795,0.00016057743,0.00002050521,0.00026300797],"genre_scores_gemma":[0.9959862,0.00066452223,0.0009801124,0.00018116555,0.00027228062,0.0000241439,0.0005761563,0.00002637096,0.001289052],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894303,0.000045020868,0.0001872885,0.00037634128,0.00013025987,0.00031806497],"domain_scores_gemma":[0.9990606,0.000009893829,0.000081170896,0.00018693697,0.000045853838,0.0006155834],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011987487,0.00021481726,0.00013636143,0.000043261138,0.00016908172,0.000042063733,0.00004650019,0.00019197972,0.000021107056],"category_scores_gemma":[0.000017725162,0.00020082106,0.00007246945,0.000045382145,0.000029857203,0.000024528917,0.000035503395,0.00006590839,0.0000048950756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021459097,0.00022730893,0.004383297,0.00007862395,0.000012830061,0.0000011805713,0.00016750961,0.0000030517174,0.9876259,0.00017775911,0.0013042015,0.005803765],"study_design_scores_gemma":[0.0031514016,0.0002970123,0.007005508,0.000023075609,0.00024603546,0.000016697413,0.00022337437,0.00091111823,0.9568316,0.0007740278,0.029893601,0.0006265658],"about_ca_topic_score_codex":0.00003234434,"about_ca_topic_score_gemma":0.0000016854116,"teacher_disagreement_score":0.0307943,"about_ca_system_score_codex":0.0000133578305,"about_ca_system_score_gemma":0.00005848659,"threshold_uncertainty_score":0.8189245},"labels":[],"label_agreement":null},{"id":"W2082494916","doi":"10.1038/cddis.2014.524","title":"Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Cell biology; Transcription factor; Caspase 1; GATA4; Biology; Caspase 3; Programmed cell death; Caspase; Caspase 8; Regulator; Caspase 2; Molecular biology; Apoptosis; Biochemistry; Gene","score_opus":0.006621323798989527,"score_gpt":0.1968441811395868,"score_spread":0.19022285734059727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082494916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938373,0.0025699104,0.0024675517,0.000011821089,0.000065891305,0.00014665216,0.00007975688,0.000004614785,0.0008164865],"genre_scores_gemma":[0.9982262,0.00079887453,0.00023112672,0.000019971558,0.000055633616,0.0000034299364,0.00018617808,0.000010724313,0.00046782612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99943167,0.00004094279,0.00014839266,0.0002026515,0.00007930953,0.00009703872],"domain_scores_gemma":[0.9995294,0.000006642878,0.00007865257,0.00017097438,0.00003835326,0.00017597311],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006714851,0.00009943367,0.0001255182,0.000031321146,0.000036819678,0.000007569591,0.000030799878,0.00007541696,0.000007125571],"category_scores_gemma":[0.000011436447,0.000090359,0.00006403834,0.000025782985,0.000042258875,0.0000056942513,0.000019637091,0.000022173232,4.9728385e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012915314,0.00004329469,0.0029032805,0.00024140281,0.000006031533,2.124823e-7,0.00003946548,0.000019660374,0.9920457,0.00025663667,0.00009104741,0.004224103],"study_design_scores_gemma":[0.0005874779,0.00019764384,0.108903766,0.000016403032,0.00008546811,4.023513e-7,0.000026145059,0.0008147293,0.88610584,0.0005214109,0.002599279,0.00014145032],"about_ca_topic_score_codex":0.000017303659,"about_ca_topic_score_gemma":0.0000014017721,"teacher_disagreement_score":0.10600049,"about_ca_system_score_codex":0.0000021870467,"about_ca_system_score_gemma":0.00002284097,"threshold_uncertainty_score":0.3684733},"labels":[],"label_agreement":null},{"id":"W2083904407","doi":"10.1038/cddis.2014.403","title":"The PERK pathway independently triggers apoptosis and a Rac1/Slpr/JNK/Dilp8 signaling favoring tissue homeostasis in a chronic ER stress Drosophila model","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Unfolded protein response; Endoplasmic reticulum; Cell biology; Apoptosis; Homeostasis; Downregulation and upregulation; ATF4; Biology; Signal transduction; RAC1; Biochemistry; Gene","score_opus":0.007262056867586713,"score_gpt":0.2238504919039147,"score_spread":0.216588435036328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083904407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9826394,0.015883328,0.00043684244,0.000118217045,0.000050719715,0.00025992058,0.00010286533,0.000013080843,0.0004956391],"genre_scores_gemma":[0.99601185,0.0031843588,0.00006828077,0.00016416224,0.00015061491,0.000074362215,0.00008136756,0.000028841125,0.0002361449],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855703,0.00008444007,0.00023509955,0.0005295948,0.00017731456,0.00041653845],"domain_scores_gemma":[0.99883586,0.000047026406,0.000077527904,0.00035609683,0.00003667752,0.00064678007],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015913924,0.00025537267,0.00018887252,0.00005283377,0.0002580672,0.00013369127,0.00016033668,0.00010622433,0.000005375558],"category_scores_gemma":[0.000101041434,0.0002010362,0.0000817829,0.000060190563,0.00011217789,0.000012722685,0.00012243788,0.00012024683,0.0000023105374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033848882,0.0011207218,0.12777053,0.0022965732,0.00026415975,0.00017708816,0.0012072762,0.040091947,0.75014055,0.0027728179,0.0009363196,0.06983712],"study_design_scores_gemma":[0.018565858,0.0012031284,0.022035796,0.0006927823,0.0008969416,0.000016764487,0.0014278415,0.13547157,0.7998666,0.0077088606,0.008619151,0.0034946757],"about_ca_topic_score_codex":0.000034872894,"about_ca_topic_score_gemma":0.000018981484,"teacher_disagreement_score":0.105734736,"about_ca_system_score_codex":0.000025725612,"about_ca_system_score_gemma":0.00019422694,"threshold_uncertainty_score":0.8198018},"labels":[],"label_agreement":null},{"id":"W2090551452","doi":"10.1038/cddis.2015.15","title":"LincRNA-p21 acts as a mediator of ING1b-induced apoptosis","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biology; Histone; Chromatin; Cell biology; Regulation of gene expression; Cell cycle; Transcription (linguistics); Genetics; Gene","score_opus":0.019456926245895432,"score_gpt":0.2762868724440845,"score_spread":0.25682994619818905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090551452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99310535,0.002670566,0.0005066419,0.00012542772,0.000115291434,0.00020241745,0.000027571492,0.000010046117,0.00323668],"genre_scores_gemma":[0.99848825,0.00036364977,0.00015141377,0.00028779113,0.00012940932,0.00002553795,0.00008301665,0.000022985765,0.00044797186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903077,0.000052016778,0.00013878403,0.00030193932,0.0002357962,0.00024070291],"domain_scores_gemma":[0.9984106,0.000007937192,0.0000534039,0.00032475052,0.00013524166,0.0010680952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012966243,0.00013092668,0.00012565845,0.000055335695,0.000035309877,0.000019936579,0.0001370492,0.00012247388,0.000023834691],"category_scores_gemma":[0.0004195883,0.00012674677,0.00007125874,0.000079729165,0.000037587437,0.000003910621,0.00015886006,0.00008177408,0.000019981424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000537583,0.00012695318,0.00031862978,0.00007244726,0.000030679097,0.000018294886,0.00004860722,0.000016465021,0.9960843,0.00011268762,0.0018646753,0.0007687301],"study_design_scores_gemma":[0.001253595,0.0003452238,0.00012337592,0.000015673191,0.00005095039,0.0000023864286,0.000058263027,0.00008785561,0.9881507,0.00038058264,0.009361538,0.00016984431],"about_ca_topic_score_codex":0.00003629565,"about_ca_topic_score_gemma":0.0000029315725,"teacher_disagreement_score":0.007933536,"about_ca_system_score_codex":0.000016146361,"about_ca_system_score_gemma":0.0006302489,"threshold_uncertainty_score":0.51685834},"labels":[],"label_agreement":null},{"id":"W2090669556","doi":"10.1038/cddis.2013.224","title":"Regulatory feedback loop between TP73 and TRIM32","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Cancer Society Research Institute; Deutsche Forschungsgemeinschaft","keywords":"Ubiquitin ligase; Transcription factor; Ubiquitin; Cell biology; Suppressor; Transcription (linguistics); Biology; Neurogenesis; Transcriptional regulation; Embryonic stem cell; Genetics; Gene","score_opus":0.01195677780452228,"score_gpt":0.22079448964629705,"score_spread":0.20883771184177477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090669556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98335457,0.009994088,0.00008154316,0.00042333885,0.00005377835,0.0004412129,0.00002082965,0.0000539444,0.005576678],"genre_scores_gemma":[0.99584424,0.0002468287,0.00012019309,0.0006591185,0.00014877746,0.00002234949,0.00004879722,0.000024076508,0.0028856096],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992066,0.000019316592,0.00013829027,0.00027942943,0.00013991621,0.0002164392],"domain_scores_gemma":[0.9983756,0.000023492008,0.000034208755,0.00027786868,0.000043752774,0.0012450733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045513443,0.00013965595,0.00019276192,0.000058864847,0.000060683557,0.00003071703,0.000033619945,0.00007470968,0.00018272182],"category_scores_gemma":[0.000052412404,0.000123516,0.000055802964,0.00006368232,0.00007696378,0.00006336052,0.00004274908,0.000111984686,0.00010952712],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095355697,0.0006069615,0.7678195,0.0021894749,0.00023874542,0.00063660135,0.00039165406,0.000008432228,0.048442353,0.0006663834,0.080137715,0.097908616],"study_design_scores_gemma":[0.005144407,0.00020556808,0.97826856,0.00014185735,0.0006265153,0.000013836396,0.000052694355,0.00020990185,0.003976213,0.0011974633,0.009834848,0.00032813862],"about_ca_topic_score_codex":0.000039683633,"about_ca_topic_score_gemma":3.9799133e-7,"teacher_disagreement_score":0.21044905,"about_ca_system_score_codex":0.000025912508,"about_ca_system_score_gemma":0.00014927161,"threshold_uncertainty_score":0.5036837},"labels":[],"label_agreement":null},{"id":"W2091440111","doi":"10.1038/cddis.2009.6","title":"Mutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3)","year":2010,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta","keywords":"Huntingtin; Mitochondrion; Huntingtin Protein; Biology; Cell biology; Programmed cell death; Huntington's disease; Apoptosis; Neuroprotection; Mutant; Molecular biology; Biochemistry; Pathology; Neuroscience; Disease; Gene; Medicine","score_opus":0.026321836504796907,"score_gpt":0.2579481946795069,"score_spread":0.23162635817471,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091440111","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99778235,0.0000277751,0.00002277652,0.00029902655,0.00024817948,0.0005015075,0.00003628268,0.000030200616,0.0010518869],"genre_scores_gemma":[0.99895185,0.0000046577543,0.000058833113,0.0005414518,0.00008587737,0.00004420825,0.0000021726898,0.000018309833,0.00029263957],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875265,0.00014114322,0.00021673518,0.00040646564,0.00026478525,0.0002182063],"domain_scores_gemma":[0.99887097,0.0001780034,0.00020691707,0.00035288095,0.000047799713,0.0003434363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007980814,0.00016298183,0.000114886956,0.000057617246,0.0002513164,0.0000841556,0.0002534408,0.000035614827,0.00007005571],"category_scores_gemma":[0.0032783828,0.00011822233,0.00007086382,0.00017384313,0.00013251047,0.0001558059,0.00015745517,0.00021971668,0.000009092803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006693491,0.00015654934,0.0084132515,0.000062400075,0.0000011308961,0.000004121402,0.000120228586,0.00001589162,0.98997587,0.0003867488,0.000034564622,0.0007623089],"study_design_scores_gemma":[0.00029799854,0.000022741659,0.030638047,0.000032275788,0.000020376585,0.000001081641,0.00006290371,0.00019496329,0.9678127,0.0004894692,0.00029973872,0.00012770525],"about_ca_topic_score_codex":0.000029786483,"about_ca_topic_score_gemma":0.0000039037814,"teacher_disagreement_score":0.022224795,"about_ca_system_score_codex":0.000008124524,"about_ca_system_score_gemma":0.0001808099,"threshold_uncertainty_score":0.48209667},"labels":[],"label_agreement":null},{"id":"W2092524362","doi":"10.1038/cddis.2013.221","title":"Signal-dependent fra-2 regulation in skeletal muscle reserve and satellite cells","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; York University; Sanofi (Canada); IONICS Mass Spectrometry (Canada); Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Satellite; Cell biology; Skeletal muscle; SIGNAL (programming language); Signal transduction; Biology; Chemistry; Anatomy; Computer science; Engineering","score_opus":0.00597002449927144,"score_gpt":0.20702296284634963,"score_spread":0.20105293834707819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092524362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938844,0.0042501343,0.00007370335,0.00007911739,0.000027304619,0.00019723574,0.000009717137,0.0000060808457,0.0014722942],"genre_scores_gemma":[0.99812704,0.00079855585,0.000058763024,0.00028975785,0.000044049655,0.000026888007,0.00010297512,0.000008874328,0.00054310577],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993221,0.000048850685,0.000110264686,0.0002928569,0.00005216963,0.00017373372],"domain_scores_gemma":[0.9995243,0.000010943955,0.000029323948,0.00016147543,0.000022848611,0.00025111245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000052492,0.00010740717,0.00007968784,0.00002908155,0.000052318122,0.00002198917,0.000050166233,0.00008263476,0.000082516664],"category_scores_gemma":[0.000016983178,0.000100646816,0.00003028889,0.000028235814,0.00005815772,0.000009420238,0.00006386607,0.000048984257,0.000016185824],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019189478,0.00024803713,0.04358079,0.00014020632,0.000011893648,0.000009751469,0.0000823405,0.00011895653,0.94187427,0.00015598378,0.0011729832,0.012412901],"study_design_scores_gemma":[0.0014394672,0.0001736207,0.95711637,0.000013873351,0.000022803195,6.3982304e-7,0.00011953427,0.0007400226,0.030321203,0.006340066,0.0033918293,0.00032056082],"about_ca_topic_score_codex":0.00008375339,"about_ca_topic_score_gemma":0.000018853547,"teacher_disagreement_score":0.9135356,"about_ca_system_score_codex":0.000003066136,"about_ca_system_score_gemma":0.000028579421,"threshold_uncertainty_score":0.41042578},"labels":[],"label_agreement":null},{"id":"W2092777567","doi":"10.1038/cddis.2014.89","title":"D-ribosylation induces cognitive impairment through RAGE-dependent astrocytic inflammation","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China; McGill University","keywords":"Glycation; Rage (emotion); Proinflammatory cytokine; Glial fibrillary acidic protein; Astrocyte; Inflammation; Downregulation and upregulation; Endocrinology; Tumor necrosis factor alpha; Astrogliosis; Chemistry; Internal medicine; Receptor; Biology; Cell biology; Medicine; Central nervous system; Neuroscience; Biochemistry; Immunohistochemistry","score_opus":0.012586043807383726,"score_gpt":0.2778541415110378,"score_spread":0.2652680977036541,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092777567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97492427,0.0005560975,0.022284932,0.00015615836,0.000043834025,0.00026750797,0.000016428638,0.000013141635,0.0017376472],"genre_scores_gemma":[0.9979608,0.00017422195,0.00035067392,0.00013438938,0.00023349198,0.000037999107,0.00035120882,0.000011148701,0.00074603315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992376,0.00006974092,0.00011062416,0.00028667334,0.00013636626,0.00015902644],"domain_scores_gemma":[0.9994782,0.00001672244,0.000050599683,0.00016063261,0.00009324214,0.00020059607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010804706,0.00009870026,0.00006170329,0.000024398065,0.00009819917,0.000029823792,0.00005245965,0.000041119994,0.000024378109],"category_scores_gemma":[0.00024172541,0.000092385686,0.000024463077,0.00003879183,0.000036104313,0.000014716125,0.000058646063,0.000051024323,0.000023869019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036618528,0.0007324338,0.053837985,0.00086329324,0.00012778188,0.000023871644,0.00089772494,0.0030735673,0.8367647,0.0028860134,0.0013275478,0.09580322],"study_design_scores_gemma":[0.004745313,0.0008519753,0.10395435,0.000060436243,0.00011990928,0.0000062416316,0.00034783108,0.0015175429,0.86334777,0.007311169,0.017051628,0.00068584457],"about_ca_topic_score_codex":0.000004218627,"about_ca_topic_score_gemma":0.0000010398855,"teacher_disagreement_score":0.09511738,"about_ca_system_score_codex":0.000012206496,"about_ca_system_score_gemma":0.00007882182,"threshold_uncertainty_score":0.3767379},"labels":[],"label_agreement":null},{"id":"W2093295909","doi":"10.1038/cddis.2015.36","title":"Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":214,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba; Children's Hospital Research Institute of Manitoba; Research Manitoba","funders":"Canadian Institutes of Health Research; University of Manitoba; Research Manitoba; University of Calgary; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Myofibroblast; Regulator; Transforming growth factor; Cell biology; Cancer research; Fibrosis; Biology; Chemistry; Medicine; Pathology; Biochemistry; Apoptosis; Gene","score_opus":0.028453738019335133,"score_gpt":0.2791710123957052,"score_spread":0.25071727437637004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093295909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924842,0.00512829,0.0000060152797,0.00011627165,0.000081883416,0.00041141556,0.000041398547,0.000050681196,0.0016798563],"genre_scores_gemma":[0.9981052,0.000055348435,0.000118087744,0.00059852184,0.00022181786,0.000014230958,0.000059005182,0.00002892542,0.0007988065],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99871194,0.000050810017,0.00033185535,0.00034083935,0.0002970862,0.00026749136],"domain_scores_gemma":[0.9981729,0.000026966898,0.00009715057,0.00040087666,0.00006986745,0.0012322436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011618234,0.00020189148,0.00038895875,0.00014561525,0.00004259348,0.0000132076875,0.00008432184,0.00009911366,0.00012503777],"category_scores_gemma":[0.0000483043,0.00018057637,0.00019401663,0.00015629259,0.000059415204,0.00008629264,0.000054829605,0.000074528696,0.000018501818],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.032073718,0.004820289,0.6538185,0.004477544,0.0005748765,0.0028728812,0.004160086,0.000045229466,0.26739162,0.0023946215,0.014462099,0.012908533],"study_design_scores_gemma":[0.024782646,0.0011449676,0.884177,0.00034063534,0.00067885336,0.000013833252,0.00016076752,0.0003797477,0.08023408,0.006377043,0.0011253513,0.00058507436],"about_ca_topic_score_codex":0.00004597467,"about_ca_topic_score_gemma":7.7378735e-7,"teacher_disagreement_score":0.2303585,"about_ca_system_score_codex":0.00006203962,"about_ca_system_score_gemma":0.0006104113,"threshold_uncertainty_score":0.7363691},"labels":[],"label_agreement":null},{"id":"W2111299532","doi":"10.1038/cddis.2015.95","title":"Mcl-1 is a key regulator of the ovarian reserve","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Oocyte; Biology; Ovarian reserve; Ovarian follicle; Cell biology; Apoptosis; Programmed cell death; Andrology; Cancer research; Follicular phase; Endocrinology; Genetics; Medicine; Embryo; Pregnancy","score_opus":0.03736563812439958,"score_gpt":0.26937738059601063,"score_spread":0.23201174247161105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111299532","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889022,0.002394117,0.000007748744,0.0022625304,0.000090005014,0.00018625188,0.000020695396,0.000009025683,0.0061274352],"genre_scores_gemma":[0.99595135,0.0000099238205,0.000051592808,0.00058477273,0.00007675368,0.000004591607,0.000005269776,0.000003592629,0.0033121628],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9995016,0.000045863184,0.00009059321,0.00018667907,0.000084391715,0.00009088623],"domain_scores_gemma":[0.9990196,0.000011041625,0.000029887236,0.0004534538,0.00008780866,0.00039819215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015037878,0.000058338846,0.000105492225,0.0000125827855,0.00003461803,0.0000025615868,0.000049664657,0.00003923521,0.000037813596],"category_scores_gemma":[0.00040228077,0.000033395627,0.00005215477,0.000050539427,0.00012498414,0.00002256928,0.00004704544,0.00005502588,0.00000682864],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045088995,0.00020257683,0.9833577,0.00010579558,0.00001679427,0.000009326814,0.000323645,2.0098659e-7,0.0011076297,0.0004270515,0.0097360555,0.00020432535],"study_design_scores_gemma":[0.00082899636,0.00006681223,0.9830786,0.000014855447,0.00008033593,0.000001955507,0.000049319468,0.00002794627,0.0038920713,0.005573924,0.006345674,0.000039523606],"about_ca_topic_score_codex":0.000035320565,"about_ca_topic_score_gemma":6.72641e-7,"teacher_disagreement_score":0.0070491494,"about_ca_system_score_codex":0.000009163951,"about_ca_system_score_gemma":0.00018210878,"threshold_uncertainty_score":0.13618341},"labels":[],"label_agreement":null},{"id":"W2139446098","doi":"10.1038/cddis.2015.278","title":"NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Mitophagy; Cell biology; Biology; Autophagy; Chemistry; Genetics; Apoptosis","score_opus":0.03642741280251954,"score_gpt":0.28925913473399323,"score_spread":0.2528317219314737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139446098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99166906,0.00568441,0.00014040602,0.00027513024,0.0001379285,0.00070454605,0.00023802764,0.000016008655,0.0011344602],"genre_scores_gemma":[0.9942136,0.00023230376,0.00014890575,0.00061039475,0.00006696258,0.00004178535,0.000022344071,0.000014723611,0.004649025],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990983,0.000029463174,0.000222639,0.00021462089,0.00024252727,0.00019247801],"domain_scores_gemma":[0.9984819,0.00014430031,0.00012254289,0.00044366528,0.00016698721,0.00064058084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009528406,0.00012676982,0.0002534642,0.00002894709,0.00004395569,0.000006279636,0.00013108218,0.000047957157,0.00009056215],"category_scores_gemma":[0.00041200637,0.00007455551,0.0001179197,0.00012070899,0.00016422289,0.00005687194,0.000045751218,0.000049383096,0.0000045603697],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.051400293,0.0059094126,0.74824977,0.008630141,0.00054752233,0.00037732976,0.0044653867,0.00007435513,0.026713915,0.0042999093,0.14478572,0.0045462623],"study_design_scores_gemma":[0.0381024,0.0022189103,0.5101307,0.0015667661,0.0017906673,0.000024273886,0.0016765742,0.012663495,0.37440944,0.016082093,0.040208045,0.0011266337],"about_ca_topic_score_codex":0.000029715284,"about_ca_topic_score_gemma":0.0000015093408,"teacher_disagreement_score":0.34769553,"about_ca_system_score_codex":0.000010735075,"about_ca_system_score_gemma":0.00047902408,"threshold_uncertainty_score":0.30402854},"labels":[],"label_agreement":null},{"id":"W2203819430","doi":"10.1038/cddis.2015.381","title":"Obesity and cancer, a case for insulin signaling","year":2015,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":144,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Overweight; Hyperinsulinemia; Obesity; Insulin resistance; Medicine; Cancer; Body mass index; Type 2 diabetes; Disease; Fatty liver; Diabetes mellitus; Internal medicine; Endocrinology","score_opus":0.03950355456338837,"score_gpt":0.31783496903590314,"score_spread":0.27833141447251475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2203819430","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0047098184,0.99342,0.000045849516,0.0000016114784,0.00015808047,0.0005777278,0.0010190083,0.000007273347,0.000060613398],"genre_scores_gemma":[0.00038584572,0.9977036,0.00009230631,0.00015390568,0.00062422326,0.00030379338,0.00042044936,0.000035926416,0.00027991814],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989467,0.000055847497,0.00020544577,0.00048337085,0.00006619355,0.00024244252],"domain_scores_gemma":[0.99881506,0.000016197131,0.00011242352,0.00023858817,0.00007381239,0.0007438962],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014140322,0.0002873721,0.00056073157,0.00003343905,0.00009251651,0.000043138247,0.00008070434,0.0001838976,0.000011137281],"category_scores_gemma":[0.00006200031,0.00023998562,0.00017222995,0.000037211274,0.00004534907,0.0000028932707,0.00008304652,0.00007157162,0.0000015253387],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003958101,0.00004509337,0.00002759417,0.010367769,0.00004590127,0.000056297158,0.000009346103,5.705669e-7,0.0000054994302,0.00001412507,0.0020780726,0.9873102],"study_design_scores_gemma":[0.00053044193,0.000043302032,0.0000015754273,0.00039497853,0.0010602397,0.000017947092,0.000007760768,0.000008313035,0.00002783725,0.000111690926,0.9974857,0.0003102349],"about_ca_topic_score_codex":0.000023916353,"about_ca_topic_score_gemma":0.0000060663933,"teacher_disagreement_score":0.9954076,"about_ca_system_score_codex":0.000013365332,"about_ca_system_score_gemma":0.00063740485,"threshold_uncertainty_score":0.9786329},"labels":[],"label_agreement":null},{"id":"W2210500005","doi":"10.1038/cddis.2015.376","title":"A minimal ING1b fragment that improves the efficacy of HDAC-based cancer cell killing","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Biology; Apoptosis; H3K4me3; Histone deacetylase; Cancer research; Ectopic expression; Cancer cell; Histone; Annexin; Programmed cell death; Cell biology; Molecular biology; Cancer; Cell culture; DNA; Genetics; Gene expression; Promoter; Gene","score_opus":0.021003935502047186,"score_gpt":0.2777429875152362,"score_spread":0.256739052013189,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2210500005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98583466,0.012588316,0.00012905672,0.00013639963,0.00008319841,0.00023006105,0.000047130936,0.000006104914,0.0009450702],"genre_scores_gemma":[0.9985859,0.00020961008,0.00011464189,0.00020769563,0.00014465838,0.00004253407,0.000050970386,0.000017069984,0.0006269457],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991159,0.00005528427,0.00012621972,0.0002688581,0.00020601308,0.00022775911],"domain_scores_gemma":[0.99903846,0.000028293112,0.000059256963,0.0003053857,0.00007718555,0.0004913962],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001393598,0.00012781617,0.000103988714,0.000020587378,0.0000713362,0.000021370592,0.00014331422,0.00005876455,0.00001517788],"category_scores_gemma":[0.000078195924,0.00009295865,0.00007865653,0.000040233426,0.00011104531,0.0000035365683,0.00008979036,0.00006495977,0.0000036169213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001769602,0.0006867648,0.014279266,0.00031470216,0.00003053126,0.000027141283,0.0003487558,0.00045708573,0.9699695,0.000011467336,0.009752237,0.0023529618],"study_design_scores_gemma":[0.0024671562,0.00028699145,0.003176572,0.000032429612,0.00006803041,5.468017e-7,0.0002521263,0.0013743818,0.975961,0.000017052731,0.016129956,0.0002337245],"about_ca_topic_score_codex":0.00016361322,"about_ca_topic_score_gemma":0.000013780727,"teacher_disagreement_score":0.012751211,"about_ca_system_score_codex":0.00002534076,"about_ca_system_score_gemma":0.000481427,"threshold_uncertainty_score":0.3790744},"labels":[],"label_agreement":null},{"id":"W2258479317","doi":"10.1038/cddis.2015.306","title":"A conserved MADS-box phosphorylation motif regulates differentiation and mitochondrial function in skeletal, cardiac, and smooth muscle cells","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada; McMaster University; York University; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Canadian Institutes of Health Research; Children's Hospital Foundation; Natural Sciences and Engineering Research Council of Canada; Manitoba Medical Service Foundation; Manitoba Health Research Council; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"Biology; Mef2; Cell biology; Transcription factor; Myocyte; Skeletal muscle; Lipotoxicity; Phosphorylation; Mitochondrion; Serum response factor; Genetics; Endocrinology; Enhancer; Insulin resistance; Gene; Insulin","score_opus":0.008634647621730869,"score_gpt":0.2060388559461461,"score_spread":0.19740420832441524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2258479317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919169,0.007029783,0.0004132477,0.00003837649,0.00017107917,0.00031674028,0.000039357532,0.000011982412,0.00006253184],"genre_scores_gemma":[0.9988375,0.00029354653,0.0001232102,0.00005045747,0.00011984143,0.000021937632,0.00040371166,0.000015564223,0.00013425089],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991819,0.00007191883,0.00015163796,0.00035386437,0.0000933503,0.0001472956],"domain_scores_gemma":[0.99931645,0.000010429936,0.00006448213,0.0001681326,0.00005069194,0.00038980026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007259498,0.00014549353,0.00011887784,0.00004820553,0.00005367121,0.000056960656,0.000028167704,0.00009938498,0.0000061831142],"category_scores_gemma":[0.00005142065,0.00014801061,0.00003732835,0.000044891993,0.000057220772,0.00001625463,0.000053899217,0.000037485064,0.0000017001182],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065397605,0.00013087147,0.058479927,0.00014394271,0.000020823749,0.0000040278105,0.00008776223,0.000104421466,0.93627554,0.000046225257,0.0012101921,0.002842311],"study_design_scores_gemma":[0.0029021173,0.00015259536,0.93664724,0.000027834341,0.00016446845,5.566361e-7,0.0000843864,0.0024613193,0.053045742,0.0012303644,0.0029503084,0.0003330539],"about_ca_topic_score_codex":0.00003527271,"about_ca_topic_score_gemma":0.000008970695,"teacher_disagreement_score":0.8832298,"about_ca_system_score_codex":0.000015761161,"about_ca_system_score_gemma":0.00006883217,"threshold_uncertainty_score":0.60356975},"labels":[],"label_agreement":null},{"id":"W2278493779","doi":"10.1038/cddis.2016.4","title":"CCAAT/enhancer binding protein beta protects muscle satellite cells from apoptosis after injury and in cancer cachexia","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Ccaat-enhancer-binding proteins; Biology; Endocrinology; Internal medicine; Myocyte; Apoptosis; Proinflammatory cytokine; Population; Inflammation; Cancer research; Cell biology; Transcription factor; Medicine; Immunology; Nuclear protein; Biochemistry","score_opus":0.006772151564473042,"score_gpt":0.22599288008547125,"score_spread":0.21922072852099822,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2278493779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922198,0.0068493267,0.000026982163,0.00014216757,0.00004754027,0.00038865922,0.00017393217,0.00000878979,0.000142797],"genre_scores_gemma":[0.9970095,0.0018946101,0.00006363753,0.000109873494,0.00007860104,0.0003411845,0.000032097385,0.000017698212,0.0004527947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902433,0.000053644464,0.00012946615,0.0004718406,0.00005638294,0.00026434884],"domain_scores_gemma":[0.99942464,0.000009655846,0.00004367135,0.0002139662,0.000017271968,0.00029078455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045620825,0.00017426032,0.0001303628,0.00003883934,0.000052371965,0.000016775297,0.000068181966,0.00011822401,0.000082727485],"category_scores_gemma":[0.000017525701,0.00013176946,0.00004196205,0.000046268742,0.00009363877,0.000010935,0.00009427715,0.000055447297,0.000009201358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008827972,0.0000736338,0.013218827,0.00006392327,0.000010865143,0.0000028514007,0.00003150174,5.756673e-7,0.9764086,0.0000035133621,0.00006355492,0.0092393765],"study_design_scores_gemma":[0.0010079631,0.00007782488,0.06779248,0.00009094836,0.000026570664,4.1963634e-8,0.000017858714,0.0000042080433,0.9279635,0.00038953268,0.002342135,0.00028692887],"about_ca_topic_score_codex":0.00011556102,"about_ca_topic_score_gemma":0.00004817599,"teacher_disagreement_score":0.05457366,"about_ca_system_score_codex":0.000010091563,"about_ca_system_score_gemma":0.000075145734,"threshold_uncertainty_score":0.5373402},"labels":[],"label_agreement":null},{"id":"W2286321980","doi":"10.1038/cddis.2016.8","title":"ANP32B deficiency impairs proliferation and suppresses tumor progression by regulating AKT phosphorylation","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Carcinogenesis; Biology; Cancer research; Cell growth; Oncogene; Protein kinase B; Gene silencing; Cancer; Knockout mouse; Phosphorylation; Cell biology; Cell cycle; Genetics","score_opus":0.006044057211147616,"score_gpt":0.23587406111479625,"score_spread":0.22983000390364863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2286321980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899001,0.0076734144,0.0017099311,0.00016708022,0.000024306994,0.0001857417,0.00003884761,0.000011299892,0.00028927682],"genre_scores_gemma":[0.99869585,0.00037224265,0.0002184119,0.00007017346,0.00005163004,0.00005103388,0.000079972575,0.000008906187,0.00045175856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994375,0.00002074476,0.00009806971,0.0002542111,0.00006798343,0.00012145458],"domain_scores_gemma":[0.99957275,0.0000059871118,0.00005003539,0.00014360185,0.00004009913,0.0001875164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053045493,0.000086207205,0.000049931234,0.000013972141,0.00012870858,0.00003591894,0.000034511948,0.00003307234,0.000010833084],"category_scores_gemma":[0.000049315073,0.000059050053,0.000018055494,0.00002503681,0.000045406043,0.000012000804,0.00002838723,0.000015274736,0.000001239495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000197941,0.00009315149,0.11581814,0.00006549866,0.0000032627313,0.0000011153697,0.000027495937,0.0000055028004,0.857512,0.00015387431,0.0026066003,0.023515442],"study_design_scores_gemma":[0.0025496788,0.00049252703,0.15572748,0.00012544617,0.00009119687,0.000008530111,0.00009932891,0.0011796409,0.82405543,0.0012244463,0.013807204,0.00063909066],"about_ca_topic_score_codex":0.000002613942,"about_ca_topic_score_gemma":6.285131e-7,"teacher_disagreement_score":0.03990934,"about_ca_system_score_codex":0.000006036975,"about_ca_system_score_gemma":0.00005479584,"threshold_uncertainty_score":0.24079913},"labels":[],"label_agreement":null},{"id":"W2292716261","doi":"10.1038/cddis.2015.406","title":"Knockout of Atg5 delays the maturation and reduces the survival of adult-generated neurons in the hippocampus","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; Mitacs; Heart and Stroke Foundation of Canada","keywords":"ATG5; Neurogenesis; Autophagy; Biology; Cell biology; Neural stem cell; Progenitor cell; Dentate gyrus; Embryonic stem cell; Hippocampal formation; Programmed cell death; Stem cell; Cellular differentiation; Apoptosis; Neuroscience; Gene; Genetics","score_opus":0.013846260004343119,"score_gpt":0.24803857195220816,"score_spread":0.23419231194786505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2292716261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99292916,0.0038456856,0.000010434204,0.0024058083,0.00005480076,0.00028948058,0.00003714389,0.0000064208484,0.00042107108],"genre_scores_gemma":[0.9981079,0.0010956407,0.0000046768755,0.00058802235,0.000060882252,0.000017043787,0.000010087707,0.000006759034,0.0001090048],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993505,0.00013315346,0.0001550417,0.00012223786,0.00013393241,0.00010516836],"domain_scores_gemma":[0.9993415,0.00018455647,0.000067269684,0.0002436734,0.000053055373,0.00010994116],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012321844,0.00008752443,0.00011468301,0.000023141078,0.00006936561,0.000010123288,0.00008424755,0.000026027992,0.000020486446],"category_scores_gemma":[0.00009923984,0.000031677817,0.000042501622,0.0000796575,0.00015792334,0.000038704344,0.000018374176,0.000051964347,0.0000013087015],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018368764,0.0027955868,0.3079807,0.0010163446,0.00036810545,0.00033588198,0.011438234,0.00003836149,0.47832304,0.018094743,0.0064922404,0.15474802],"study_design_scores_gemma":[0.003080612,0.00022687805,0.96673596,0.00012400032,0.00034894084,0.000009220582,0.0009024639,0.00040889977,0.020224644,0.007529487,0.0002840139,0.00012488423],"about_ca_topic_score_codex":0.000022073109,"about_ca_topic_score_gemma":0.0000042383995,"teacher_disagreement_score":0.65875524,"about_ca_system_score_codex":0.00000380184,"about_ca_system_score_gemma":0.00008733876,"threshold_uncertainty_score":0.12917839},"labels":[],"label_agreement":null},{"id":"W2293146769","doi":"10.1038/cddis.2015.259","title":"Intrinsic hypoxia sensitivity of the cytomegalovirus promoter","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Hospital; Sunnybrook Health Science Centre","funders":"Deutsche Forschungsgemeinschaft; European Commission","keywords":"Hypoxia (environmental); Sensitivity (control systems); Chemistry; Biology; Cell biology; Molecular biology; Oxygen","score_opus":0.035755684909033705,"score_gpt":0.2833438607620579,"score_spread":0.24758817585302423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2293146769","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99025464,0.0010192493,0.000023826697,0.0007616326,0.000067685374,0.00041033654,0.000041006864,0.000021620472,0.0074000163],"genre_scores_gemma":[0.9975774,0.00003969264,0.00005740491,0.00052307406,0.00010668016,0.000008496256,0.00000645744,0.000014738885,0.0016660049],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99897075,0.0000934987,0.00015239339,0.00021578594,0.00034268785,0.00022487243],"domain_scores_gemma":[0.9983403,0.000048626167,0.00004325254,0.00038693883,0.00015385731,0.001026998],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033583227,0.00012039785,0.0002076515,0.00006720078,0.00006145509,0.00002249708,0.000058422484,0.00004902271,0.000038250666],"category_scores_gemma":[0.00036692581,0.00007569381,0.000098364515,0.00016205359,0.00014285899,0.000060387596,0.00013867482,0.00016176145,0.00005129408],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004434876,0.0014001781,0.91876704,0.0009463828,0.000083980456,0.00084358914,0.0006408421,0.0000073066117,0.030042773,0.0013877251,0.01158656,0.029858744],"study_design_scores_gemma":[0.0041268403,0.00023892362,0.95309573,0.00009733428,0.00023776967,0.000046947574,0.000096481286,0.000994442,0.012029756,0.0018083187,0.026977085,0.0002503429],"about_ca_topic_score_codex":0.00016586784,"about_ca_topic_score_gemma":0.000013288715,"teacher_disagreement_score":0.034328718,"about_ca_system_score_codex":0.000039371786,"about_ca_system_score_gemma":0.0005324284,"threshold_uncertainty_score":0.3086704},"labels":[],"label_agreement":null},{"id":"W2332226611","doi":"10.1038/cddis.2016.55","title":"Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada","funders":"Ministero della Salute; European Commission","keywords":"ELISPOT; Ebola virus; T cell; Immunology; Immune system; CD8; Flow cytometry; Medicine; Biology; Virology; Virus","score_opus":0.020101215387148194,"score_gpt":0.28126344215219273,"score_spread":0.2611622267650445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2332226611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99624234,0.00001636129,0.0019730874,0.0001319589,0.00005370496,0.00018633477,0.00002517161,0.000032085074,0.0013389512],"genre_scores_gemma":[0.9955027,0.00011808812,0.000009647798,0.000025750931,0.00014769244,0.000021404925,0.00009790497,0.000010812704,0.004065985],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999368,0.000019646848,0.00014326937,0.00018094611,0.0001556929,0.00013242813],"domain_scores_gemma":[0.9994373,0.000011024877,0.000059636273,0.000107865955,0.00011184746,0.00027235417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047201433,0.00008808905,0.00010662344,0.00014261757,0.0001525403,0.000015456104,0.000014461655,0.00004179988,0.00031428068],"category_scores_gemma":[0.000019196616,0.00006260856,0.00005725592,0.00009917395,0.00004093221,0.00020042363,0.000024205703,0.000055140536,0.000020027017],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027885972,0.00015753566,0.28231502,0.00013673285,0.000012732795,0.0000064183514,0.000008306327,3.4700153e-7,0.7163415,0.000077461096,0.000024539995,0.0006405171],"study_design_scores_gemma":[0.0012337897,0.00014357247,0.8049015,0.00005545348,0.00007181173,0.000004797886,0.000001522086,0.000036739963,0.19327578,0.000052020216,0.00016032561,0.00006269331],"about_ca_topic_score_codex":0.00003385063,"about_ca_topic_score_gemma":5.994571e-7,"teacher_disagreement_score":0.52306575,"about_ca_system_score_codex":0.000045771016,"about_ca_system_score_gemma":0.000064807835,"threshold_uncertainty_score":0.34411532},"labels":[],"label_agreement":null},{"id":"W2333840024","doi":"10.1038/cddis.2016.80","title":"Eiger-induced cell death relies on Rac1-dependent endocytosis","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia; McGill University; Montreal Neurological Institute and Hospital","funders":"Universität Zürich; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Endocytosis; RAC1; Cell biology; Programmed cell death; Cell; Chemistry; Biology; Signal transduction; Apoptosis; Biochemistry","score_opus":0.012060240023455295,"score_gpt":0.21519181996382106,"score_spread":0.20313157994036576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2333840024","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917735,0.0014712798,0.0014571196,0.00013303898,0.000120257944,0.00017794599,0.00006516785,0.00002260081,0.0047791237],"genre_scores_gemma":[0.9939426,0.0013942028,0.000047437377,0.0003445867,0.00017268349,0.00002386318,0.0004591502,0.00002518649,0.0035902758],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894273,0.000032453212,0.00015661617,0.00044832675,0.00014818,0.00027168132],"domain_scores_gemma":[0.9990621,0.00001365744,0.00004982504,0.00035002065,0.00003575178,0.00048859563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006629774,0.00020165324,0.00012563613,0.000040613875,0.0001045968,0.000025289839,0.000104134706,0.00010471666,0.000079720914],"category_scores_gemma":[0.000023716477,0.00014655663,0.00011753697,0.000025303485,0.0000280014,0.0000057240363,0.000036582787,0.0000514499,0.000052401523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005150079,0.00016680859,0.029157095,0.00004517943,0.000011161226,0.000050319526,0.000019878056,0.0000018680493,0.9683454,0.00012493967,0.0001756893,0.0013866596],"study_design_scores_gemma":[0.0024698896,0.0004628351,0.028750801,0.00003841999,0.00012257688,0.0000030479525,0.000032336593,0.000015743235,0.9414864,0.00037376164,0.025764467,0.0004797246],"about_ca_topic_score_codex":0.000013101335,"about_ca_topic_score_gemma":0.0000042517763,"teacher_disagreement_score":0.026858998,"about_ca_system_score_codex":0.000012859773,"about_ca_system_score_gemma":0.00008110908,"threshold_uncertainty_score":0.59764063},"labels":[],"label_agreement":null},{"id":"W2341302423","doi":"10.1038/cddis.2015.229","title":"CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"China Scholarship Council; Canadian Institutes of Health Research; Ovarian Cancer Canada","keywords":"Necroptosis; Programmed cell death; Cancer research; CD40; Biology; Apoptosis; Serous fluid; Cell biology; Chemistry; Cytotoxic T cell; Biochemistry","score_opus":0.01339596502421113,"score_gpt":0.22972313811973608,"score_spread":0.21632717309552493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2341302423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99441063,0.0029439947,0.0005815962,0.000095499774,0.00036536192,0.00048482156,0.00013303237,0.000034839588,0.00095019955],"genre_scores_gemma":[0.9939268,0.00059751037,0.0005902154,0.0007560484,0.00026484398,0.000039952785,0.00041262418,0.000059550348,0.0033524488],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978843,0.000091536014,0.00038856815,0.0007947302,0.00028736552,0.0005535003],"domain_scores_gemma":[0.9981334,0.000014243706,0.00015107472,0.0005097037,0.00010271571,0.0010888621],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022119081,0.0004117783,0.00030908492,0.000116006806,0.00013744475,0.00012015735,0.0002296076,0.0002354758,0.000015036069],"category_scores_gemma":[0.00003323028,0.0003825699,0.0001168197,0.00012468187,0.00005276944,0.000022040273,0.0001919401,0.00017673806,0.000024515644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009171739,0.00095752656,0.0073346198,0.0002710178,0.000027203241,0.00032489884,0.00015521246,0.0009725176,0.9876319,0.00009990079,0.0006368757,0.0006711225],"study_design_scores_gemma":[0.0062111737,0.00054354686,0.013049366,0.00006621462,0.00018206848,0.000027247403,0.00031192362,0.0019992448,0.97012997,0.00080478704,0.0056424006,0.0010320394],"about_ca_topic_score_codex":0.00029928164,"about_ca_topic_score_gemma":0.00006367477,"teacher_disagreement_score":0.017501943,"about_ca_system_score_codex":0.000035574743,"about_ca_system_score_gemma":0.00033549062,"threshold_uncertainty_score":0.9998626},"labels":[],"label_agreement":null},{"id":"W2343658748","doi":"10.1038/cddis.2016.104","title":"GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington’s disease: involvement of astrocyte–neuron interactions","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"NIHR Cambridge Biomedical Research Centre; National Institute for Health and Care Research; Canadian Institutes of Health Research; Ministero dell’Istruzione, dell’Università e della Ricerca; Ministero della Salute; Fonds de Recherche du Québec - Santé","keywords":"Hippocampal formation; Astrocyte; Dentate gyrus; GSK-3; GSK3B; Biology; Hippocampus; Neurodegeneration; Neuroscience; Downregulation and upregulation; Genetically modified mouse; Programmed cell death; Cell biology; Transgene; Internal medicine; Phosphorylation; Medicine; Central nervous system; Disease; Apoptosis; Biochemistry","score_opus":0.028624268160496263,"score_gpt":0.2620132500512763,"score_spread":0.23338898189078003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2343658748","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99762213,0.0001666319,0.00016017511,0.00032999186,0.00036916372,0.00051520084,0.00031011098,0.000056126075,0.00047048205],"genre_scores_gemma":[0.9980429,0.00018532717,0.000087824315,0.0008902928,0.000092431925,0.00011622587,0.000017437882,0.000045788813,0.00052179483],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9970081,0.00045190487,0.00048303892,0.0010677188,0.00038075013,0.00060848234],"domain_scores_gemma":[0.997606,0.0003435911,0.00022319426,0.0005561423,0.00006604889,0.0012050237],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008159763,0.00038887214,0.00030851056,0.0002613918,0.00015786382,0.000053027816,0.0003315381,0.000041088293,0.00015149632],"category_scores_gemma":[0.00065638573,0.00031862568,0.00016249383,0.00018568637,0.00017838269,0.00023759618,0.00027719844,0.00015913018,0.000041249386],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043370802,0.00095332484,0.21076235,0.000113354574,0.0000021249068,0.0001248077,0.00009316293,0.000053135198,0.78624254,0.00034975176,0.00014137669,0.0007303751],"study_design_scores_gemma":[0.0015732363,0.0002064161,0.5113423,0.000052719166,0.00006973556,0.0000012354806,0.00004062617,0.00014988067,0.48533353,0.0006684697,0.00026333772,0.00029852643],"about_ca_topic_score_codex":0.000012210357,"about_ca_topic_score_gemma":0.000008665311,"teacher_disagreement_score":0.300909,"about_ca_system_score_codex":0.00004884317,"about_ca_system_score_gemma":0.00032708977,"threshold_uncertainty_score":0.99992657},"labels":[],"label_agreement":null},{"id":"W2343834046","doi":"10.1038/cddis.2016.102","title":"CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Partenariat Canadien Contre Le Cancer; Bundesministerium für Bildung und Forschung; Deutsches Krebsforschungszentrum","keywords":"Temozolomide; Fas receptor; Cancer research; Cancer stem cell; Epithelial–mesenchymal transition; Biology; Stem cell; Apoptosis; Cancer; Glioblastoma; Programmed cell death; Cell biology; Metastasis; Genetics","score_opus":0.014672973620530744,"score_gpt":0.23379010012995768,"score_spread":0.21911712650942694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2343834046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935353,0.0018526098,0.000111219495,0.00029395524,0.00010114484,0.00063084776,0.000047499107,0.000042490097,0.0033849648],"genre_scores_gemma":[0.9923161,0.00063725765,0.00013069696,0.00059293816,0.00013261211,0.000060918985,0.000019127547,0.00003405504,0.0060762507],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99852395,0.00003534925,0.0002592205,0.00050835067,0.00022237377,0.00045075294],"domain_scores_gemma":[0.9982008,0.000036578473,0.00006152519,0.00031622438,0.000032930886,0.0013519594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011083439,0.00024756242,0.00035424592,0.00011539711,0.00008160429,0.00004233347,0.000065872664,0.0000785934,0.00006419355],"category_scores_gemma":[0.0000034812267,0.00017043712,0.00010069986,0.00011097232,0.0001451965,0.000083470855,0.000096967415,0.00011905097,0.000026752467],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00575639,0.0046657114,0.3908393,0.004753731,0.000081329,0.0036301287,0.00087425974,0.0000015158047,0.27784717,0.00031650925,0.011304843,0.2999291],"study_design_scores_gemma":[0.058804657,0.006251557,0.67662066,0.0023519874,0.0021991518,0.00008543571,0.0011910814,0.00025996272,0.086309694,0.0012948237,0.16167828,0.0029527033],"about_ca_topic_score_codex":0.000030535335,"about_ca_topic_score_gemma":0.000025207935,"teacher_disagreement_score":0.29697642,"about_ca_system_score_codex":0.000097659155,"about_ca_system_score_gemma":0.00020783568,"threshold_uncertainty_score":0.69502246},"labels":[],"label_agreement":null},{"id":"W2346309969","doi":"10.1038/cddis.2016.119","title":"SP6616 as a new Kv2.1 channel inhibitor efficiently promotes β-cell survival involving both PKC/Erk1/2 and CaM/PI3K/Akt signaling pathways","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology; Department of Medicine, University of Toronto; University of Toronto; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Protein kinase B; Protein kinase C; Kinase; PI3K/AKT/mTOR pathway; Protein kinase A; Signal transduction; Cell biology; Biology; Pharmacology; Internal medicine; Chemistry; Endocrinology; Cancer research; Biochemistry; Medicine","score_opus":0.019080114881134813,"score_gpt":0.21984052659008302,"score_spread":0.2007604117089482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2346309969","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869945,0.0074717533,0.0003232937,0.00046455176,0.00025274628,0.0004639566,0.00004466047,0.00012351337,0.003861045],"genre_scores_gemma":[0.9906645,0.00019108485,0.00016797,0.0009942505,0.00047298733,0.00001906211,0.000027735881,0.000038100025,0.007424332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983939,0.00005313186,0.00027068914,0.0005296163,0.00029703238,0.00045563953],"domain_scores_gemma":[0.99700314,0.00023774027,0.00009066903,0.00027653694,0.00007049879,0.0023214235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019038322,0.00029517955,0.0003649155,0.00012747991,0.00016968141,0.000074013384,0.000058712005,0.00012041385,0.00020453593],"category_scores_gemma":[0.00073219085,0.00020108969,0.000094989045,0.00012232816,0.00008873047,0.00012699615,0.00007613393,0.0001282343,0.00008345189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026571797,0.0017191548,0.2602245,0.0024994619,0.00011130064,0.00052795885,0.0016979609,0.000007915302,0.7118648,0.0011571555,0.009234237,0.008298361],"study_design_scores_gemma":[0.08363557,0.0067971474,0.08845855,0.0074448283,0.0043378156,0.00010328869,0.0044626575,0.006672846,0.7569345,0.0140731605,0.021957655,0.0051219743],"about_ca_topic_score_codex":0.00007328982,"about_ca_topic_score_gemma":0.000001384924,"teacher_disagreement_score":0.17176592,"about_ca_system_score_codex":0.00003947714,"about_ca_system_score_gemma":0.0005474451,"threshold_uncertainty_score":0.82001996},"labels":[],"label_agreement":null},{"id":"W2353728735","doi":"10.1038/cddis.2016.121","title":"Stalled replication forks within heterochromatin require ATRX for protection","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Ottawa Hospital Research Institute; Canadian Institutes of Health Research; Cancer Research Society; University of Ottawa","keywords":"ATRX; Biology; Death-associated protein 6; Heterochromatin; Telomere; DNA repair; Cell biology; Chromatin; Genetics; Mutation; Nuclear protein; DNA; Gene","score_opus":0.013766574695041993,"score_gpt":0.2397357054457381,"score_spread":0.2259691307506961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2353728735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9046311,0.000269265,0.093964584,0.00017188469,0.000056123616,0.0006652356,0.000041292627,0.00002985609,0.00017071178],"genre_scores_gemma":[0.9954446,0.00002908577,0.0015333481,0.00012517822,0.000093155046,0.0003094499,0.00006508023,0.000016453943,0.002383661],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993489,0.00001910478,0.00011216383,0.00034498973,0.000051781382,0.00012306668],"domain_scores_gemma":[0.99933755,0.0000049277123,0.00006378201,0.0003570232,0.000041490122,0.0001952481],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095309704,0.000089023764,0.000059732396,0.000014813067,0.00006782031,0.000014978237,0.000052910942,0.00006607239,0.000006755366],"category_scores_gemma":[0.00015444861,0.00006506176,0.000053380532,0.000015235589,0.000018482384,0.0000072541934,0.000034786255,0.00001414976,0.000003652784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037725316,0.00003733466,0.00018763426,0.0000745555,0.000006880308,8.0217484e-7,0.000010332419,0.0000016842465,0.993329,0.00027174663,0.00026287764,0.005439931],"study_design_scores_gemma":[0.0017591971,0.0005125021,0.00083016825,0.0000383981,0.000038751496,0.0000035067433,0.000019649498,0.00071906624,0.9817993,0.007143991,0.0068997615,0.00023568494],"about_ca_topic_score_codex":0.0000017623172,"about_ca_topic_score_gemma":0.0000012802205,"teacher_disagreement_score":0.09243123,"about_ca_system_score_codex":0.000009466309,"about_ca_system_score_gemma":0.00004478663,"threshold_uncertainty_score":0.26531413},"labels":[],"label_agreement":null},{"id":"W2395217429","doi":"10.1038/cddis.2015.293","title":"Heart disease: recruitment of MEF2 activity by β−blockers wards off cardiomyocyte death","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada); York University","funders":"","keywords":"Mef2; Heart failure; Programmed cell death; Myocyte; Myocardial infarction; Apoptosis; Medicine; Disease; Ventricular remodeling; Internal medicine; Heart disease; Cardiac function curve; Regeneration (biology); Biology; Cardiology; Cell biology; Transcription factor; Gene; Enhancer","score_opus":0.051536947235735354,"score_gpt":0.2989218122399547,"score_spread":0.24738486500421933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2395217429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96850336,0.027034158,0.00014852962,0.0011233811,0.00019245353,0.0007188792,0.0002538775,0.00005079516,0.0019745526],"genre_scores_gemma":[0.99745166,0.00055243395,0.00025915136,0.00035838113,0.00014219515,0.000040927043,0.000092874856,0.000027161519,0.0010752368],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986363,0.00006160546,0.00019884748,0.000376231,0.00043455834,0.00029242755],"domain_scores_gemma":[0.9969571,0.000023986624,0.000059075628,0.00042157123,0.0001194917,0.0024187749],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019740156,0.00021235249,0.00045010468,0.00006348823,0.0000656454,0.000021662907,0.000047686004,0.000060277518,0.00001088474],"category_scores_gemma":[0.00008729743,0.00017096008,0.00028676662,0.00008462,0.00007118585,0.00007518717,0.0000729607,0.000102866165,0.000010405514],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01584434,0.0026887911,0.769353,0.0026911984,0.00048164494,0.00026802375,0.00061725423,0.00057898794,0.028061576,0.00031845216,0.15645617,0.022640584],"study_design_scores_gemma":[0.015434258,0.00088291365,0.59793997,0.0007738626,0.0051167947,0.000031260723,0.0004117607,0.013052653,0.012626828,0.0010956697,0.35117346,0.0014605665],"about_ca_topic_score_codex":0.00008504363,"about_ca_topic_score_gemma":2.6049173e-7,"teacher_disagreement_score":0.19471729,"about_ca_system_score_codex":0.00009149969,"about_ca_system_score_gemma":0.00049693923,"threshold_uncertainty_score":0.69715494},"labels":[],"label_agreement":null},{"id":"W2406289188","doi":"10.1038/cddis.2016.141","title":"Myt3 suppression sensitizes islet cells to high glucose-induced cell death via Bim induction","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Child and Family Research Institute; BC Children's Hospital","funders":"Canadian Institutes of Health Research; Child and Family Research Institute; Canadian Diabetes Association","keywords":"Islet; Cell biology; Programmed cell death; Apoptosis; Chemistry; Cancer research; Biology; Endocrinology; Diabetes mellitus; Biochemistry","score_opus":0.013766907713524533,"score_gpt":0.232117276770007,"score_spread":0.21835036905648247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2406289188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939622,0.00036962616,0.000886442,0.0009370189,0.00059944845,0.00043837138,0.00005554382,0.00013209341,0.0026192444],"genre_scores_gemma":[0.99287444,0.00013646677,0.00052391225,0.0017872531,0.0003848733,0.00002862245,0.000049711358,0.000033740085,0.0041809934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985489,0.00006536442,0.00023777648,0.000492026,0.00026820763,0.00038771355],"domain_scores_gemma":[0.9977206,0.00011267616,0.00006751487,0.00036968797,0.00009936726,0.0016301477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000098189885,0.00026307677,0.0003112726,0.00016375537,0.00013434555,0.000032824308,0.000050189003,0.00011729178,0.00039084847],"category_scores_gemma":[0.00012534198,0.00017312048,0.00009737216,0.00012636933,0.000031004776,0.00012302128,0.000058379108,0.000093880706,0.00046940925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080880517,0.00029144704,0.009070547,0.00015335571,0.000014555639,0.00008943539,0.00004342382,0.0000013472566,0.9789597,0.000052622992,0.0059298696,0.004584934],"study_design_scores_gemma":[0.0040413984,0.00040571138,0.042427648,0.00018687594,0.00032505248,0.000007150544,0.00006730718,0.00011716418,0.94730926,0.00065311784,0.004115462,0.0003438812],"about_ca_topic_score_codex":0.000053995635,"about_ca_topic_score_gemma":3.515353e-7,"teacher_disagreement_score":0.0333571,"about_ca_system_score_codex":0.000058054324,"about_ca_system_score_gemma":0.00012788422,"threshold_uncertainty_score":0.7059648},"labels":[],"label_agreement":null},{"id":"W2415524742","doi":"10.1038/cddis.2015.289","title":"DAB2IP loss confers the resistance of prostate cancer to androgen deprivation therapy through activating STAT3 and inhibiting apoptosis","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Fundamental Research Funds for the Central Universities; National Cancer Institute; National Institutes of Health; U.S. Army; National Key Research and Development Program of China; China Scholarship Council; Terry Fox Foundation; National Natural Science Foundation of China","keywords":"Survivin; Gene knockdown; Transactivation; Apoptosis; Cancer research; Androgen deprivation therapy; STAT3; Prostate cancer; Biology; STAT protein; Signal transduction; Cell biology; Transcription factor; Chemistry; Cancer; Gene","score_opus":0.05218983459364644,"score_gpt":0.3273599306588932,"score_spread":0.2751700960652467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2415524742","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98634565,0.00933099,0.000039450148,0.002586164,0.000021144278,0.0007295344,0.000057554225,0.000015227209,0.0008743048],"genre_scores_gemma":[0.99554235,0.003001374,0.0002171815,0.00048239427,0.0000442309,0.0000997874,0.000028028826,0.0000140637085,0.00057061034],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918455,0.000035339293,0.00013968935,0.00021893287,0.00021631473,0.00020515943],"domain_scores_gemma":[0.9991882,0.000054427044,0.0000618131,0.00014094407,0.00014836217,0.00040624948],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013786403,0.000111636604,0.00014820157,0.000032678432,0.00011286173,0.00003178289,0.000037029567,0.000023124741,0.000007318011],"category_scores_gemma":[0.00008949025,0.000068746784,0.000023770363,0.0001328112,0.00009744376,0.000107925756,0.000040672367,0.000068432026,6.725848e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008928278,0.00022482351,0.940037,0.00069777266,0.00011249616,0.00003697723,0.011260506,0.000025699695,0.017903771,0.00034664845,0.0015579629,0.018868025],"study_design_scores_gemma":[0.027101234,0.0011085011,0.20878707,0.0014639829,0.00035813806,0.0000054361335,0.01023934,0.00039237543,0.7219365,0.0066285543,0.02116828,0.0008105851],"about_ca_topic_score_codex":0.00014866414,"about_ca_topic_score_gemma":0.0000062305676,"teacher_disagreement_score":0.73125,"about_ca_system_score_codex":0.00004810514,"about_ca_system_score_gemma":0.00031757963,"threshold_uncertainty_score":0.28034124},"labels":[],"label_agreement":null},{"id":"W2438926523","doi":"10.1038/cddis.2015.286","title":"Bcl-2 proteins, cell migration and embryonic development: lessons from zebrafish","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; Biology; Bcl-2 family; Endoplasmic reticulum; Mitochondrion; Apoptosis; Programmed cell death; Zebrafish; Genetics; Gene","score_opus":0.018111562673030022,"score_gpt":0.23336764125068593,"score_spread":0.2152560785776559,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2438926523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906991,0.0055325,0.0015392957,0.00028604508,0.00017151333,0.00019805178,0.00004182521,0.000013900127,0.0015177461],"genre_scores_gemma":[0.9937103,0.00028175424,0.0013516434,0.0005741121,0.00019901029,0.00003625185,0.00059148663,0.000012334915,0.003243108],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99934894,0.000046497782,0.000098159624,0.0003071156,0.00006328936,0.00013597679],"domain_scores_gemma":[0.99925596,0.000005248429,0.00003794992,0.00015591155,0.00003700254,0.000507912],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054289656,0.000114563096,0.00008356639,0.00002181203,0.000074257674,0.000033410746,0.000046151465,0.00008898398,0.000018411354],"category_scores_gemma":[0.0000512661,0.00010589795,0.00002308029,0.000023877374,0.000029801975,0.000005015145,0.000056110595,0.000043469732,0.000022893544],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018465186,0.00045756032,0.09849253,0.00016860629,0.000039077087,0.00006533414,0.0006737218,0.000017839724,0.86006725,0.0002545306,0.03164402,0.0062730354],"study_design_scores_gemma":[0.005157158,0.00049153593,0.047734827,0.000028068675,0.00012752274,0.0000087691915,0.00031491191,0.00021352357,0.18549469,0.0012361279,0.7583965,0.00079635484],"about_ca_topic_score_codex":0.000025356256,"about_ca_topic_score_gemma":0.00005863753,"teacher_disagreement_score":0.7267525,"about_ca_system_score_codex":0.0000053470685,"about_ca_system_score_gemma":0.00020231826,"threshold_uncertainty_score":0.4318393},"labels":[],"label_agreement":null},{"id":"W2440552260","doi":"10.1038/cddis.2016.176","title":"α-Integrin expression and function modulates presentation of cell surface calreticulin","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; BC Children's Hospital","keywords":"Calreticulin; Endoplasmic reticulum; Cell biology; Cytosol; Integrin; Biology; Molecular biology; Cell; Biochemistry","score_opus":0.009261048712581741,"score_gpt":0.21505319211753568,"score_spread":0.20579214340495394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2440552260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903885,0.007552568,0.0014236371,0.00006321903,0.00010891413,0.0001305115,0.000024791285,0.000017036955,0.00029079168],"genre_scores_gemma":[0.99762386,0.0004028105,0.000052716125,0.000015388521,0.000009218556,0.0000043381956,0.00004845075,0.000006360634,0.0018368616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946576,0.00007184117,0.00014292405,0.0001802137,0.000024008958,0.0001152543],"domain_scores_gemma":[0.9996504,0.000061857856,0.000073568095,0.00011842948,0.000035489,0.000060244587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000556768,0.0000921484,0.000110874484,0.000029149807,0.000066884524,0.0000069281764,0.00003074084,0.00007279471,0.00011429931],"category_scores_gemma":[0.00002575653,0.00005897662,0.000031744392,0.000025014555,0.00007593725,0.00011927852,0.000035882535,0.00003473007,0.000018191256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035910372,0.0000778651,0.020889334,0.000049876722,0.0000060412194,4.1509492e-7,0.000056491688,0.000008681534,0.9762735,0.00010516148,0.00033437382,0.001839154],"study_design_scores_gemma":[0.00151015,0.00008595824,0.16635509,0.000050183113,0.000054476102,8.409044e-7,0.000051169605,0.00008204573,0.8304437,0.00062311837,0.0006510505,0.00009223338],"about_ca_topic_score_codex":0.000020352009,"about_ca_topic_score_gemma":3.843779e-7,"teacher_disagreement_score":0.14582981,"about_ca_system_score_codex":0.000007151879,"about_ca_system_score_gemma":0.000020902322,"threshold_uncertainty_score":0.24049968},"labels":[],"label_agreement":null},{"id":"W2469624798","doi":"10.1038/cddis.2016.175","title":"NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Sorafenib; Gene knockdown; Gene silencing; Cancer research; Cell growth; RELB; Viability assay; Biology; Cell migration; Cell; Apoptosis; Transcription factor; Hepatocellular carcinoma; Gene; NFKB1","score_opus":0.014564043899337454,"score_gpt":0.24282913339359755,"score_spread":0.22826508949426008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2469624798","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868806,0.008745751,0.0007156172,0.0026559967,0.000035772016,0.0003129023,0.000032294873,0.000016899146,0.00060418353],"genre_scores_gemma":[0.99509007,0.0030068243,0.00024045321,0.00033556367,0.000085683474,0.00003884434,0.000017810917,0.000009782569,0.0011749987],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993348,0.000021342385,0.00018631383,0.00024285175,0.000073938754,0.0001407645],"domain_scores_gemma":[0.999392,0.00006465802,0.00005474468,0.0001102947,0.00004940006,0.0003289512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000060443697,0.0000978083,0.0001428981,0.00010095339,0.00004130818,0.000017355535,0.000024768478,0.000036795875,0.00006155585],"category_scores_gemma":[0.000088597975,0.00007201615,0.000028651557,0.000086721615,0.000021177933,0.0001249911,0.00001257341,0.00006144133,0.0000052207943],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024783236,0.0003971192,0.5812013,0.00041502647,0.000008065412,0.000096033815,0.00075352617,0.000017492797,0.40435666,0.000703339,0.0068398346,0.002733246],"study_design_scores_gemma":[0.023853015,0.00028421314,0.8267669,0.0021835444,0.00025255987,0.0000086160835,0.00024424522,0.003633071,0.1064167,0.008878256,0.026745804,0.00073307083],"about_ca_topic_score_codex":0.00047168284,"about_ca_topic_score_gemma":0.00043236566,"teacher_disagreement_score":0.29793996,"about_ca_system_score_codex":0.0000534433,"about_ca_system_score_gemma":0.00018146366,"threshold_uncertainty_score":0.29367334},"labels":[],"label_agreement":null},{"id":"W2479546137","doi":"10.1038/cddis.2016.217","title":"Tankyrase inhibition aggravates kidney injury in the absence of CD2AP","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, San Diego; School of Medicine, New York University; Päivikki ja Sakari Sohlbergin Säätiö; Sigrid Juséliuksen Säätiö; Suomen Kulttuurirahasto; Academy of Finland; York University; Helsingin Yliopisto","keywords":"Podocyte; Wnt signaling pathway; Cell biology; Downregulation and upregulation; Podocin; Kidney; Biology; Molecular biology; Cancer research; Signal transduction; Endocrinology; Biochemistry","score_opus":0.008799326773894244,"score_gpt":0.24281498488122027,"score_spread":0.23401565810732602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2479546137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99508977,0.0019386781,0.000021718566,0.00139143,0.000025403568,0.00019903351,0.00017179159,0.000011154781,0.0011510474],"genre_scores_gemma":[0.9972811,0.0012734343,0.000018554054,0.001103563,0.000046458452,0.00001892131,0.000024993926,0.000005928011,0.00022704573],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993745,0.00003270979,0.00015148846,0.00015207705,0.00015166693,0.00013752255],"domain_scores_gemma":[0.99922377,0.00004339565,0.00004549102,0.00019016507,0.000035041638,0.0004621633],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008664276,0.00009084278,0.00011948791,0.00006448841,0.000030670817,0.0000094716415,0.000035101082,0.000024023273,0.00006833205],"category_scores_gemma":[0.00027892075,0.00004499406,0.00006104864,0.000100542085,0.00009635366,0.00006609503,0.000019462414,0.000037794594,0.000013954554],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023270433,0.00096114946,0.8898714,0.0015624202,0.0000139612475,0.0006486772,0.00036799573,3.5637345e-7,0.07555039,0.003006128,0.012641149,0.0130493],"study_design_scores_gemma":[0.0022146872,0.0002741423,0.975662,0.001112717,0.000114293216,0.000007295963,0.00015413274,0.000026111478,0.008518272,0.009057218,0.0026842214,0.00017494147],"about_ca_topic_score_codex":0.000022326629,"about_ca_topic_score_gemma":4.586488e-7,"teacher_disagreement_score":0.08579054,"about_ca_system_score_codex":0.000008267146,"about_ca_system_score_gemma":0.00011789432,"threshold_uncertainty_score":0.18348046},"labels":[],"label_agreement":null},{"id":"W2488521558","doi":"10.1038/cddis.2016.208","title":"Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":621,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"Lapatinib; Programmed cell death; SKBR3; Apoptosis; Cancer research; Cancer cell; Chemistry; Deferoxamine; Transferrin receptor; Necroptosis; Pharmacology; Cell; Cancer; Medicine; Breast cancer; Internal medicine; Biochemistry; Trastuzumab","score_opus":0.023970344376195604,"score_gpt":0.2768163075986351,"score_spread":0.2528459632224395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2488521558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932327,0.004051776,0.000007842217,0.0017315126,0.000076687254,0.00028611175,0.00022475338,0.000020952917,0.00036761124],"genre_scores_gemma":[0.9953323,0.0033583406,0.00006694252,0.0004739386,0.000078471676,0.00007253454,0.000005201612,0.000020297908,0.00059197744],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.999152,0.00001676138,0.0001754774,0.00030353616,0.00014599694,0.00020622373],"domain_scores_gemma":[0.99902886,0.000030423693,0.000059647224,0.00020103593,0.000045990564,0.000634056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000027142489,0.00017754184,0.00030673985,0.000054150063,0.00005356251,0.0000132924015,0.000028117587,0.000050114068,0.00024846353],"category_scores_gemma":[0.000007792597,0.00010589029,0.00012435342,0.000071611845,0.0000401518,0.000061175524,0.000021897627,0.000022590873,0.0000042099055],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00092125987,0.0007854019,0.7083796,0.0003050159,0.00014489885,0.00003644533,0.00037589076,1.395539e-7,0.17105164,0.000020780766,0.0006564587,0.117322445],"study_design_scores_gemma":[0.009142418,0.0009371078,0.73909724,0.0005479741,0.0015039444,0.0000044595904,0.00013613091,0.000057612022,0.24626426,0.000073822375,0.0018760881,0.0003589131],"about_ca_topic_score_codex":0.00019271253,"about_ca_topic_score_gemma":0.0000028596962,"teacher_disagreement_score":0.11696353,"about_ca_system_score_codex":0.00004982125,"about_ca_system_score_gemma":0.00013742567,"threshold_uncertainty_score":0.43180808},"labels":[],"label_agreement":null},{"id":"W2515293382","doi":"10.1038/cddis.2016.210","title":"Regulatory non-coding RNA: new instruments in the orchestration of cell death","year":2016,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Necroptosis; Biology; microRNA; Non-coding RNA; RNA; Programmed cell death; Computational biology; Cell biology; RNA interference; Gene expression; Gene; Regulation of gene expression; Long non-coding RNA; Transcription (linguistics); Genetics; Apoptosis","score_opus":0.022932339350997068,"score_gpt":0.2736583233367659,"score_spread":0.2507259839857688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2515293382","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0374942,0.95996255,0.00019745638,0.000009150177,0.00007575484,0.00072039897,0.000087537286,0.00000487621,0.0014480775],"genre_scores_gemma":[0.1296216,0.86898345,0.000105365805,0.00004384262,0.00022290919,0.000040494822,0.0004561406,0.000031570653,0.00049462763],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986904,0.00012431064,0.0003915281,0.0004186345,0.00015936127,0.00021576043],"domain_scores_gemma":[0.9988546,0.000021320106,0.00027706503,0.00052217534,0.000028083665,0.00029675462],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015948416,0.0002929131,0.0003735642,0.00008211334,0.00004781664,0.000028571214,0.00024076678,0.00021205263,0.000014904612],"category_scores_gemma":[0.000042248732,0.00019864735,0.00022253429,0.00007842097,0.000043470372,0.000008318701,0.00008337888,0.0000849487,0.000007952217],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004318386,0.00100689,0.0038392162,0.05034196,0.00022093872,0.00007942769,0.00017287229,0.000012599736,0.048820425,0.000742016,0.006748894,0.8875829],"study_design_scores_gemma":[0.0045396704,0.0003574785,0.014451392,0.013072577,0.0025230998,0.000020627398,0.000057495643,0.000075585274,0.015435878,0.0015631443,0.9457505,0.0021525938],"about_ca_topic_score_codex":0.000008383787,"about_ca_topic_score_gemma":0.000001227694,"teacher_disagreement_score":0.93900156,"about_ca_system_score_codex":0.00003236321,"about_ca_system_score_gemma":0.0007764031,"threshold_uncertainty_score":0.8100604},"labels":[],"label_agreement":null},{"id":"W2524656042","doi":"10.1038/cddis.2016.277","title":"Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Medicinal Plants and Neuroprotection","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Glaucoma Research Society of Canada; Glaucoma Research Foundation","keywords":"Astrocyte; Gliosis; Cell biology; Glial fibrillary acidic protein; Biology; p38 mitogen-activated protein kinases; Neuroinflammation; Neuroglia; MAPK/ERK pathway; Kainic acid; Neuroscience; Chemistry; Glutamate receptor; Signal transduction; Inflammation; Biochemistry; Central nervous system; Immunology; Receptor","score_opus":0.017800986334195856,"score_gpt":0.24760044347340623,"score_spread":0.22979945713921038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2524656042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99674636,0.00014602333,0.00008388588,0.0008200122,0.000096800744,0.00028634022,0.00006689129,0.000034514345,0.001719187],"genre_scores_gemma":[0.99825346,0.00040861065,0.000013751872,0.0008371259,0.00010594385,0.000019911005,0.000020999943,0.000008777484,0.00033142496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928296,0.000034519737,0.00014873588,0.00022053347,0.00017172005,0.0001415203],"domain_scores_gemma":[0.9991714,0.00009232562,0.00007552356,0.00009584874,0.000056764682,0.0005081383],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006227906,0.00010516489,0.00015512978,0.00008802605,0.00004234594,0.0000034129778,0.000018810875,0.000039570037,0.00026702805],"category_scores_gemma":[0.0002064433,0.000063239146,0.000049649356,0.000079792466,0.0000613907,0.00005645015,0.000017841898,0.00007420831,0.000014424961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023858023,0.00033699305,0.011401184,0.0001540589,0.000015901474,0.00006597356,0.000024899211,1.7517871e-7,0.9792119,0.000016984133,0.0015682197,0.0048179044],"study_design_scores_gemma":[0.0066065136,0.0012435564,0.16086167,0.00031409264,0.0006263144,0.000018144809,0.000038880666,0.000115758296,0.82750636,0.0003113016,0.0021475914,0.00020981053],"about_ca_topic_score_codex":0.000011771298,"about_ca_topic_score_gemma":1.4009005e-7,"teacher_disagreement_score":0.15170553,"about_ca_system_score_codex":0.00001546387,"about_ca_system_score_gemma":0.00006230302,"threshold_uncertainty_score":0.292377},"labels":[],"label_agreement":null},{"id":"W2528244543","doi":"10.1038/cddis.2016.298","title":"Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology","keywords":"DNA damage; Cancer research; DNA repair; Myeloid; DNA; Biology; Medicine; Genetics","score_opus":0.01834096728404802,"score_gpt":0.2578202535658038,"score_spread":0.23947928628175577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2528244543","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993768,0.00089620496,0.00016441024,0.0012967899,0.000023122326,0.00062000385,0.000088213135,0.00020839198,0.0029348698],"genre_scores_gemma":[0.9773058,0.0012279776,0.00030667218,0.0009321496,0.000035506368,0.000060347593,0.000054843993,0.000053275773,0.020023393],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99828345,0.00007858249,0.00030076646,0.0005161356,0.0002876062,0.00053347833],"domain_scores_gemma":[0.997964,0.00010031292,0.000048703445,0.00056188303,0.00008923406,0.0012358649],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022275708,0.00024240755,0.0002888874,0.00021905013,0.00007575479,0.000019950066,0.000121794095,0.00013727823,0.00016159716],"category_scores_gemma":[0.00022060855,0.00015830762,0.00012371315,0.0002159497,0.0001235034,0.00015019796,0.000094124276,0.00022662223,0.00013967804],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014939033,0.002220675,0.37586975,0.0005116041,0.00022621086,0.004097822,0.0012804539,0.00032612972,0.56390435,0.0009000098,0.020137476,0.015586488],"study_design_scores_gemma":[0.09589176,0.0016453036,0.246948,0.0008750083,0.0005028487,0.00008289955,0.0004167744,0.5839508,0.054383803,0.0066188285,0.0062177936,0.0024661305],"about_ca_topic_score_codex":0.00005809959,"about_ca_topic_score_gemma":0.0000063112675,"teacher_disagreement_score":0.5836247,"about_ca_system_score_codex":0.00018257467,"about_ca_system_score_gemma":0.0006661967,"threshold_uncertainty_score":0.6455598},"labels":[],"label_agreement":null},{"id":"W2531369023","doi":"10.1038/cddis.2016.315","title":"DDX3 DEAD-box RNA helicase plays a central role in mitochondrial protein quality control in Leishmania","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Cell biology; Biology; Proteostasis; HSPA9; Mitochondrion; DNAJA3; DEAD box; Unfolded protein response; RNA Helicase A; Helicase; Mitophagy; Mitochondrial ROS; mitochondrial fusion; Biochemistry; Mitochondrial DNA; Autophagy; RNA; Endoplasmic reticulum; Apoptosis; Gene; Peptide sequence","score_opus":0.017167401971787,"score_gpt":0.2853361433244375,"score_spread":0.2681687413526505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2531369023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99269164,0.0008068051,0.00035506557,0.0026636622,0.000032396467,0.0012970311,0.00030910148,0.00003058017,0.0018137319],"genre_scores_gemma":[0.99790406,0.00006830144,0.00013267269,0.00035945937,0.00018459161,0.00027073972,0.000031894695,0.000014766546,0.0010335136],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984079,0.000105962565,0.00031521675,0.00037309714,0.00023667386,0.00056113326],"domain_scores_gemma":[0.9981284,0.00010487475,0.000045977587,0.00035657402,0.00004740372,0.0013167263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000038630744,0.0001515382,0.00025741666,0.00012882912,0.00005454225,0.00003218358,0.000093026094,0.00006733703,0.0002051627],"category_scores_gemma":[0.0006623845,0.00010783455,0.000070551374,0.00013756071,0.00008617677,0.00012253759,0.000040294868,0.00014304211,0.000059739494],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0049934443,0.0011262177,0.20235686,0.00016682966,0.000012317714,0.00035358753,0.00010371428,5.8078734e-7,0.7825842,0.002123145,0.0011985535,0.004980541],"study_design_scores_gemma":[0.012951269,0.00016958827,0.97576326,0.00013533601,0.000021969508,0.0000049834757,0.00006658517,0.00008655539,0.006016843,0.0014380816,0.0031617638,0.00018374402],"about_ca_topic_score_codex":0.00027928854,"about_ca_topic_score_gemma":0.00016980557,"teacher_disagreement_score":0.77656734,"about_ca_system_score_codex":0.000113860675,"about_ca_system_score_gemma":0.000399817,"threshold_uncertainty_score":0.43973655},"labels":[],"label_agreement":null},{"id":"W2562624124","doi":"10.1038/cddis.2016.430","title":"Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Vlaamse regering; Veterinärmedizinische Universität Wien; China Scholarship Council; University of Toronto; Fonds Wetenschappelijk Onderzoek; Case Western Reserve University; Cincinnati Children's Hospital Medical Center","keywords":"STAT5; Cancer research; Phosphorylation; NPM1; Nucleophosmin; Biology; Signal transduction; Downregulation and upregulation; Cell biology; Biochemistry; Gene","score_opus":0.006670559581811605,"score_gpt":0.2131861053391705,"score_spread":0.20651554575735892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2562624124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98205674,0.014913629,0.00057718,0.0004077722,0.00011614828,0.00036965887,0.000057229558,0.000108720196,0.0013929373],"genre_scores_gemma":[0.9956941,0.0013164805,0.0002478854,0.00034140045,0.0000669799,0.00001977219,0.00003968895,0.000037689417,0.0022359854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988713,0.000025820129,0.00018195281,0.00042947507,0.00019279821,0.00029860766],"domain_scores_gemma":[0.99828464,0.000041238443,0.00005746649,0.00035994634,0.000058822905,0.0011978807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006426037,0.00020339094,0.00021691158,0.0000702826,0.000092578855,0.00002263251,0.00004521054,0.000100824545,0.00023144283],"category_scores_gemma":[0.00009036863,0.00013756446,0.00006830431,0.0000753188,0.00010212824,0.000081847895,0.00006995886,0.00009010558,0.000041040574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015305454,0.00025509734,0.014358546,0.00025623475,0.0000388203,0.00054715975,0.00017320251,0.0000029961373,0.9550667,0.000064966414,0.0064252,0.021280577],"study_design_scores_gemma":[0.019992944,0.00077515905,0.15744108,0.001646742,0.0010061829,0.00010279428,0.00011025088,0.00094871403,0.7746414,0.003923874,0.038298275,0.0011125833],"about_ca_topic_score_codex":0.00002520683,"about_ca_topic_score_gemma":0.0000012386955,"teacher_disagreement_score":0.18042526,"about_ca_system_score_codex":0.000044015207,"about_ca_system_score_gemma":0.00013649608,"threshold_uncertainty_score":0.5609716},"labels":[],"label_agreement":null},{"id":"W2567455682","doi":"10.1038/cddis.2016.431","title":"Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Ontario Ministry of Research and Innovation; Canadian Institutes of Health Research","keywords":"Efferocytosis; Phagosome; Phagocytosis; Cell biology; Endosome; Antigen presentation; Antigen; Antigen processing; Phagolysosome; Macrophage; Biology; Cross-presentation; MHC class II; MHC class I; Immune system; Major histocompatibility complex; Immunology; Intracellular; T cell; Biochemistry; In vitro","score_opus":0.0102668355585334,"score_gpt":0.22208695934837122,"score_spread":0.21182012378983783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2567455682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9828077,0.015845075,0.0003680602,0.00019156754,0.00031687896,0.00017557452,0.000028505941,0.00006475395,0.0002018722],"genre_scores_gemma":[0.9980572,0.0011535895,0.000020615804,0.00008028069,0.000048051166,0.000022640968,0.00005300086,0.000018711267,0.0005459095],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99889004,0.00009511907,0.00024519867,0.00036770094,0.000044343727,0.0003575807],"domain_scores_gemma":[0.999367,0.0001562035,0.00009275276,0.00019454477,0.000020516054,0.00016899654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009574997,0.00021247388,0.00027145445,0.000079255115,0.00034163872,0.00003817859,0.0000900641,0.00011318886,0.00016565107],"category_scores_gemma":[0.000119726945,0.00014172091,0.0001228303,0.00004449182,0.00009815903,0.00018669869,0.000115890056,0.00006412722,0.00005135407],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019543839,0.000075645614,0.1892213,0.000036670317,0.00007933188,0.0000060894185,0.000086908796,9.2951325e-8,0.79167926,0.00013895478,0.00020119829,0.018279133],"study_design_scores_gemma":[0.005180122,0.000109128705,0.60231566,0.00014104378,0.00034120228,0.000005996374,0.000059514026,0.000026179625,0.38904554,0.00094293227,0.0013861953,0.0004464663],"about_ca_topic_score_codex":0.000017811859,"about_ca_topic_score_gemma":0.0000010196802,"teacher_disagreement_score":0.4130944,"about_ca_system_score_codex":0.000016853995,"about_ca_system_score_gemma":0.000036619578,"threshold_uncertainty_score":0.57792115},"labels":[],"label_agreement":null},{"id":"W2574062068","doi":"10.1038/cddis.2016.455","title":"Curcumin represses mouse 3T3-L1 cell adipogenic differentiation via inhibiting miR-17-5p and stimulating the Wnt signalling pathway effector Tcf7l2","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; Diabetes Canada; University of Toronto; University Health Network","funders":"Banting and Best Diabetes Centre, University of Toronto","keywords":"Adipogenesis; Wnt signaling pathway; TCF7L2; Cell biology; Curcumin; Biology; Effector; Cellular differentiation; Adipose tissue; Adipocyte; microRNA; Signal transduction; Cancer research; Endocrinology; Biochemistry; Gene","score_opus":0.010178958059172266,"score_gpt":0.2280117057256616,"score_spread":0.21783274766648933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2574062068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898762,0.005504069,0.0039076502,0.000035096353,0.000048948295,0.0003995152,0.000058130016,0.000018502624,0.00015184833],"genre_scores_gemma":[0.9988889,0.000090589034,0.00016819482,0.000068307345,0.00021932097,0.000035120596,0.0002502371,0.000030104206,0.0002492174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988572,0.00008518681,0.00020807206,0.00047066165,0.0001304657,0.00024842468],"domain_scores_gemma":[0.99890506,0.000045841687,0.00020008089,0.00045807325,0.000052655872,0.00033829338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014519492,0.00021605738,0.00013584824,0.000025904745,0.0006156589,0.00021540467,0.00014931272,0.00008988915,0.000014991783],"category_scores_gemma":[0.0001850094,0.00017583782,0.000090933696,0.000018372999,0.000088109286,0.000017596565,0.00021144905,0.00007669156,0.0000034615512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012567904,0.00006659105,0.020700336,0.00022569553,0.00001881279,0.0000059591034,0.000044985096,0.0004296709,0.9773465,0.000008182442,0.000061004845,0.0009666141],"study_design_scores_gemma":[0.0012673239,0.0000799126,0.0577896,0.00007406967,0.00020766423,0.0000025082566,0.00002802465,0.013188787,0.92656404,0.00018214004,0.00024010135,0.00037582353],"about_ca_topic_score_codex":0.000026214382,"about_ca_topic_score_gemma":0.000004901678,"teacher_disagreement_score":0.050782427,"about_ca_system_score_codex":0.000011450701,"about_ca_system_score_gemma":0.000053932094,"threshold_uncertainty_score":0.7170458},"labels":[],"label_agreement":null},{"id":"W2583633091","doi":"10.1038/cddis.2016.483","title":"Augmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Necroptosis; Programmed cell death; Cell biology; Apoptosis; Biology; RIPK1; Trophoblast; Ceramide; Cancer research; Placenta; Biochemistry","score_opus":0.01665561599638902,"score_gpt":0.247838893395047,"score_spread":0.231183277398658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2583633091","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9769736,0.004477667,0.000036802947,0.00071925024,0.00014654218,0.0009068065,0.000086275846,0.00009085568,0.016562218],"genre_scores_gemma":[0.99545026,0.0010741246,0.00015577243,0.0005360432,0.000090425594,0.00014623503,0.000102517464,0.00003811698,0.002406511],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99825984,0.000042798725,0.00031946148,0.00056485896,0.0002543804,0.0005586391],"domain_scores_gemma":[0.99805063,0.000054540702,0.0001652341,0.0006587722,0.000075771015,0.000995057],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010050737,0.00035487325,0.00046560407,0.0001225704,0.00046247168,0.00009648548,0.00020814444,0.00011851512,0.000060437917],"category_scores_gemma":[0.0002151096,0.00030525425,0.00012227052,0.00008707466,0.00015267127,0.00015600858,0.00017610585,0.00025070398,0.00003079338],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013389289,0.00061941746,0.99054056,0.00090662314,0.00004550456,0.0003788781,0.00050692784,0.0000032928438,0.004135599,0.000038312977,0.00064669,0.00083929003],"study_design_scores_gemma":[0.0063417214,0.00023323309,0.98706543,0.0003978227,0.0003179034,0.000005351113,0.000090457135,0.0010441729,0.0026298705,0.00056270993,0.00093289255,0.0003784188],"about_ca_topic_score_codex":0.0003850186,"about_ca_topic_score_gemma":0.00008490334,"teacher_disagreement_score":0.018476672,"about_ca_system_score_codex":0.00007250315,"about_ca_system_score_gemma":0.00024779915,"threshold_uncertainty_score":0.99994},"labels":[],"label_agreement":null},{"id":"W2583659255","doi":"10.1038/cddis.2017.19","title":"Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta; Alberta Cancer Foundation; Women and Children's Health Research Institute; Children's Health Research Institute; University of Pittsburgh","keywords":"Reactive oxygen species; Apoptosis; Cancer cell; Cell biology; Mitochondrion; Chemistry; DNA damage; In vivo; Programmed cell death; In vitro; Photodynamic therapy; Cell culture; Cancer research; Cancer; Biophysics; Biochemistry; Biology; DNA","score_opus":0.014383274079486733,"score_gpt":0.2798573820609205,"score_spread":0.2654741079814337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2583659255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981589,0.0009285991,0.00009350908,0.0003910334,0.000043024098,0.00022887895,0.00002285791,0.0000027640021,0.00013048454],"genre_scores_gemma":[0.998509,0.0008171504,0.000016242037,0.000047136087,0.0000901335,0.000046394136,0.000024877661,0.00000690894,0.00044219664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99953127,0.000029068533,0.00006694269,0.00020145673,0.00007713496,0.00009415753],"domain_scores_gemma":[0.9994972,0.0000033409797,0.000076298296,0.00024005368,0.00008261549,0.00010051638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004684037,0.00006809227,0.00005810813,0.000013828052,0.00027726142,0.000030581446,0.00006979294,0.000037743444,0.0000059273234],"category_scores_gemma":[0.00021642928,0.000050228376,0.00003084612,0.000022940678,0.00009173048,0.00001058543,0.000070157155,0.00003283394,2.8387228e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026048755,0.00006494679,0.07469954,0.00007951682,0.000020986858,1.5558435e-7,0.000032500942,0.000022135244,0.9213583,0.000010088789,0.00033608856,0.0031152787],"study_design_scores_gemma":[0.00024888146,0.000029325667,0.12530671,0.000022419574,0.000037216418,1.6791758e-7,0.000023421782,0.00025160963,0.87361616,0.00012881857,0.00026987755,0.00006539046],"about_ca_topic_score_codex":0.0002668411,"about_ca_topic_score_gemma":0.00001412488,"teacher_disagreement_score":0.050607167,"about_ca_system_score_codex":0.000007012978,"about_ca_system_score_gemma":0.000090648304,"threshold_uncertainty_score":0.21324986},"labels":[],"label_agreement":null},{"id":"W2591685132","doi":"10.1038/cddis.2017.55","title":"Caspases play in traffic","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Caspase; Cell biology; Apoptosis; Biology; Programmed cell death; Genetics","score_opus":0.009974607288055493,"score_gpt":0.23795571050749909,"score_spread":0.2279811032194436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2591685132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962567,0.001966936,0.00008792198,0.000074305826,0.00007920979,0.00009378513,0.000011875971,0.0000046048244,0.001424659],"genre_scores_gemma":[0.99765056,0.00049090054,0.00007718084,0.00008773241,0.000097181815,0.000008606126,0.000059588878,0.000008044479,0.0015201746],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995451,0.000010325308,0.00006960283,0.0002046653,0.00004475999,0.0001255319],"domain_scores_gemma":[0.99946034,0.0000025866284,0.000035301593,0.0002796372,0.000010793533,0.00021134915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004208288,0.00008016837,0.00006043469,0.000019980062,0.00022638676,0.00003812911,0.000078012425,0.000051514995,0.0000141948],"category_scores_gemma":[0.00003783146,0.00007098851,0.000034117093,0.0000076583565,0.000032449618,0.00000392328,0.00007618785,0.000025227608,0.0000034771867],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018748144,0.0013710154,0.26259163,0.0005096731,0.000055603603,0.0008070339,0.00048861036,0.0028677906,0.60601044,0.0038233618,0.0054644616,0.11413553],"study_design_scores_gemma":[0.0041549294,0.00029525495,0.90580213,0.000057745325,0.00008397417,0.000012172487,0.000081956605,0.004355255,0.03324649,0.0016188694,0.049518265,0.00077295164],"about_ca_topic_score_codex":0.000015912601,"about_ca_topic_score_gemma":0.00002661205,"teacher_disagreement_score":0.6432105,"about_ca_system_score_codex":0.0000030264846,"about_ca_system_score_gemma":0.0000410461,"threshold_uncertainty_score":0.28948274},"labels":[],"label_agreement":null},{"id":"W2595555301","doi":"10.1038/cddis.2017.112","title":"Immunoproteomic identification and characterization of Ni2+-regulated proteins implicates Ni2+ in the induction of monocyte cell death","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Trace Elements in Health","field":"Nursing","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"European Social Fund; Universität Heidelberg; European Commission","keywords":"Programmed cell death; Monocyte; Apoptosis; Cell biology; Biology; Immune system; Chemistry; Cytoskeleton; Cell; Molecular biology; Immunology; Biochemistry","score_opus":0.022554410920092027,"score_gpt":0.280539826085716,"score_spread":0.25798541516562395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2595555301","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997714,0.00033233585,0.00008573184,0.000382899,0.00011408899,0.0012406638,0.00005751598,0.000013641937,0.00005914664],"genre_scores_gemma":[0.9994786,0.00012519403,0.00010864777,0.00002718543,0.000033156426,0.000075697964,0.00008958669,0.00001404633,0.000047902708],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99901634,0.000091575814,0.00035151807,0.00024447322,0.00013389795,0.00016218853],"domain_scores_gemma":[0.99882036,0.000020396968,0.0004818352,0.000524003,0.00005629546,0.00009713313],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002737819,0.000117290605,0.0001460988,0.000088014254,0.0002354037,0.00007489545,0.00017427199,0.000060792896,0.00000488275],"category_scores_gemma":[0.000056706325,0.000098372126,0.000026037174,0.000057372607,0.00008234,0.00029960877,0.00003903375,0.00009143999,0.0000014763312],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042407739,0.00023741502,0.15778176,0.00047736504,0.000003873123,8.5632905e-7,0.0005713051,0.000002893942,0.8332111,0.0001048641,0.000004862096,0.0071795722],"study_design_scores_gemma":[0.0006428451,0.000060703886,0.78743386,0.000050393257,0.00004109312,6.226767e-7,0.000057535784,0.0003296577,0.21036734,0.0009223375,0.000020771064,0.000072830866],"about_ca_topic_score_codex":0.00038317655,"about_ca_topic_score_gemma":0.000006598872,"teacher_disagreement_score":0.6296521,"about_ca_system_score_codex":0.000031211293,"about_ca_system_score_gemma":0.0000404103,"threshold_uncertainty_score":0.4011499},"labels":[],"label_agreement":null},{"id":"W2597977295","doi":"10.1038/cddis.2017.151","title":"Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Death-associated protein 6; Promyelocytic leukemia protein; Biology; C2C12; Cell biology; Chromatin; MyoD; Cellular differentiation; Nuclear protein; Myocyte; Transcription factor; Myogenesis; Genetics; DNA; Gene","score_opus":0.004421072612571143,"score_gpt":0.20930969386581894,"score_spread":0.2048886212532478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2597977295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99819416,0.00045161706,0.00029759115,0.00018838957,0.000115303534,0.00011250219,0.0000166808,0.000009323664,0.0006144622],"genre_scores_gemma":[0.9985958,0.00037496298,0.000042651045,0.00035401355,0.00014191821,0.0000017001847,0.000098306686,0.0000135924965,0.00037705572],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99951464,0.000013504063,0.000068118265,0.00023696777,0.0000559466,0.00011084559],"domain_scores_gemma":[0.99940205,0.000001709174,0.000043987176,0.00024399311,0.000023178776,0.00028510822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002234375,0.000089381094,0.00006247833,0.00001938563,0.00026037567,0.00009985045,0.000060628663,0.000055605324,0.000026102916],"category_scores_gemma":[0.000057957404,0.00008156688,0.000028538674,0.000011302475,0.000035978323,0.000008362903,0.000071419134,0.000024128623,0.0000072306366],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030655893,0.00028011878,0.32747725,0.00036863246,0.00012788312,0.000050065108,0.0003234464,0.000056127723,0.6202649,0.0025615513,0.02032265,0.025101818],"study_design_scores_gemma":[0.0015792676,0.00026251873,0.9435693,0.000020437561,0.00015927858,0.0000049824366,0.000040367704,0.0009088581,0.01051757,0.0006360386,0.041951794,0.00034956733],"about_ca_topic_score_codex":0.000010751823,"about_ca_topic_score_gemma":0.0000023941366,"teacher_disagreement_score":0.6160921,"about_ca_system_score_codex":0.0000047277367,"about_ca_system_score_gemma":0.000016484553,"threshold_uncertainty_score":0.33262008},"labels":[],"label_agreement":null},{"id":"W2598983248","doi":"10.1038/cddis.2017.92","title":"Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Cure Brain Cancer Foundation","keywords":"Triple-negative breast cancer; Cancer research; Breast cancer; Apoptosis; Cell growth; Transcription factor; Cancer; Medicine; Biology; Internal medicine","score_opus":0.012912985959583333,"score_gpt":0.24910482499677897,"score_spread":0.23619183903719562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2598983248","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99339736,0.0027966932,0.000064750384,0.0013888024,0.00020759495,0.00035053183,0.00025982526,0.0000138745745,0.0015205917],"genre_scores_gemma":[0.99821126,0.0012331755,0.000022589467,0.00017567718,0.00009366838,0.00002019656,0.000011897966,0.0000142677,0.00021727958],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993767,0.000030028956,0.00011053246,0.00020096016,0.00013826163,0.00014352292],"domain_scores_gemma":[0.9991567,0.000033718992,0.00010729436,0.00029330634,0.00007380982,0.0003351341],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000662858,0.00011188222,0.00016574311,0.000026745074,0.00021919298,0.000034125896,0.0000677682,0.000039646842,0.000034198565],"category_scores_gemma":[0.00009276218,0.000077323915,0.000054620406,0.000030366598,0.00020570534,0.00005678128,0.000056831,0.00008736658,0.0000025975892],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0053810226,0.00059587276,0.73347324,0.0015780852,0.00026739432,0.00025370333,0.0012722011,0.000014921425,0.24123354,0.0010951931,0.0049355556,0.009899255],"study_design_scores_gemma":[0.0041961875,0.00009564989,0.9471224,0.00015798632,0.000589152,0.000009558475,0.00013791338,0.00047112873,0.046211302,0.00063333433,0.00020273702,0.00017263701],"about_ca_topic_score_codex":0.00081302173,"about_ca_topic_score_gemma":0.00003452133,"teacher_disagreement_score":0.21364917,"about_ca_system_score_codex":0.000014781903,"about_ca_system_score_gemma":0.00014349127,"threshold_uncertainty_score":0.31531778},"labels":[],"label_agreement":null},{"id":"W2604122152","doi":"10.1038/cddis.2017.152","title":"cPLA2α mediates TGF-β-induced epithelial–mesenchymal transition in breast cancer through PI3k/Akt signaling","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; National Natural Science Foundation of China","keywords":"Epithelial–mesenchymal transition; Protein kinase B; Cancer research; PI3K/AKT/mTOR pathway; Signal transduction; Breast cancer; Cell biology; Transforming growth factor; Chemistry; Transition (genetics); Biology; Cancer; Medicine; Internal medicine; Biochemistry; Gene","score_opus":0.02530419893340158,"score_gpt":0.2886639169571518,"score_spread":0.26335971802375024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604122152","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937503,0.0016312212,0.000030127705,0.002298499,0.0003632035,0.00036452778,0.00016926568,0.000030522304,0.0013623635],"genre_scores_gemma":[0.9980531,0.00041727538,0.00013625583,0.000777185,0.00038988574,0.00007041539,0.000027365018,0.000025630146,0.000102933685],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99883854,0.000031482545,0.00019757437,0.00037087532,0.00023877382,0.0003227694],"domain_scores_gemma":[0.998953,0.000041630254,0.000080308324,0.00033493162,0.00006305174,0.0005270746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009142906,0.00019791284,0.0002570401,0.000052816715,0.00019123103,0.00005760436,0.000109482666,0.000093661154,0.000382361],"category_scores_gemma":[0.000074202086,0.0001707059,0.00007726996,0.00004676988,0.00009052499,0.00014528849,0.000036017853,0.00016525161,0.000013870567],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004762275,0.0006996404,0.692664,0.0012048616,0.00007332494,0.0008043834,0.0033097873,0.00017660597,0.28212708,0.00007504527,0.0007882788,0.01331468],"study_design_scores_gemma":[0.0057465485,0.00021399076,0.93032813,0.00048712993,0.00037796705,0.000021487385,0.00025221432,0.0010111441,0.058886725,0.0018632939,0.00032726247,0.0004841146],"about_ca_topic_score_codex":0.0007483089,"about_ca_topic_score_gemma":0.00004962674,"teacher_disagreement_score":0.23766409,"about_ca_system_score_codex":0.00007249734,"about_ca_system_score_gemma":0.00033164085,"threshold_uncertainty_score":0.6961184},"labels":[],"label_agreement":null},{"id":"W2613949981","doi":"10.1038/cddis.2016.474","title":"Drosophila caspase activity is required independently of apoptosis to produce active TNF/Eiger during nociceptive sensitization","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Bee Products Chemical Analysis","field":"Agricultural and Biological Sciences","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; National Cancer Institute; Institute of Genetics; University of Texas MD Anderson Cancer Center; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; American Heart Association","keywords":"Sensitization; Nociception; Cell biology; Tumor necrosis factor alpha; Chemistry; Biology; Cancer research; Immunology; Receptor; Biochemistry","score_opus":0.019259573466268675,"score_gpt":0.22987230096631997,"score_spread":0.2106127275000513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2613949981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946858,0.000039313294,0.0000014971721,0.0043498157,0.00003240545,0.00023036654,0.0001616307,0.00001771144,0.0004814531],"genre_scores_gemma":[0.9989148,0.00002732113,0.000030345192,0.00014767631,0.00017757973,0.000012553767,0.000026127274,0.0000016541319,0.00066193973],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988826,0.00003638673,0.0001287243,0.0005273187,0.00020643712,0.0002185469],"domain_scores_gemma":[0.9989598,0.000038604878,0.00017078234,0.00019529936,0.00014066623,0.000494853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006634549,0.00015375979,0.00020070032,0.000016629674,0.00040242902,0.00008189121,0.00017526897,0.000060277103,0.00010206689],"category_scores_gemma":[0.0003161135,0.000074047115,0.000090446076,0.00012353949,0.00007765712,0.00028856797,0.00020140248,0.00007341165,0.000017754473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035769184,0.00016387337,0.019366333,0.00004397493,0.000020050999,0.000005542714,0.00015083217,0.0000023734387,0.9736459,0.000008440575,0.00006682774,0.006168106],"study_design_scores_gemma":[0.00012597996,0.000027516431,0.40203413,0.00001456569,0.00006968354,3.3502207e-7,0.0000383555,0.000024731738,0.5971601,0.0003505147,0.000017681114,0.00013640423],"about_ca_topic_score_codex":0.0003344343,"about_ca_topic_score_gemma":0.000027455582,"teacher_disagreement_score":0.38266778,"about_ca_system_score_codex":0.000026580086,"about_ca_system_score_gemma":0.0000148481095,"threshold_uncertainty_score":0.30951992},"labels":[],"label_agreement":null},{"id":"W2616589397","doi":"10.1038/cddis.2017.193","title":"Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University; Health Sciences North","funders":"National Natural Science Foundation of China; Harbin Medical University","keywords":"Calcium-sensing receptor; MFN1; Internal medicine; Endocrinology; MFN2; Calcium in biology; DNM1L; Cell biology; Downregulation and upregulation; Calcium metabolism; Mitochondrion; Chemistry; Biology; Mitochondrial fission; Calcium; Intracellular; mitochondrial fusion; Medicine; Biochemistry","score_opus":0.016357706151726565,"score_gpt":0.23650452005352904,"score_spread":0.22014681390180246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2616589397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99174726,0.002521324,0.0029990522,0.0004435269,0.0006977912,0.00082003686,0.000025518579,0.00013979932,0.0006057048],"genre_scores_gemma":[0.9969428,0.00016902608,0.00023469939,0.00036369447,0.0006908616,0.000053233387,0.00006280444,0.000056653433,0.0014261974],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983218,0.000094873525,0.00023611923,0.0005459973,0.00037641003,0.00042481915],"domain_scores_gemma":[0.9977806,0.000020338255,0.00015068674,0.0007583078,0.00012633341,0.0011636835],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001704945,0.0003145354,0.00046074233,0.00010942793,0.0006862315,0.00015175024,0.00008928256,0.00013946774,0.00009011725],"category_scores_gemma":[0.00027971945,0.0002497714,0.00033897054,0.00006741736,0.00007878037,0.00014908718,0.00011543892,0.00021892175,0.000029512019],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037367777,0.0013025714,0.05102313,0.0014942681,0.00085492275,0.0021434966,0.0005222567,0.00002457512,0.42855307,0.00092709396,0.0008207885,0.508597],"study_design_scores_gemma":[0.013009578,0.00030302253,0.35185292,0.00046927226,0.0015925207,0.0001295988,0.00019548193,0.0021794767,0.49057955,0.00079692126,0.13734867,0.0015429942],"about_ca_topic_score_codex":0.0007922091,"about_ca_topic_score_gemma":0.000012105188,"teacher_disagreement_score":0.50705403,"about_ca_system_score_codex":0.000040493444,"about_ca_system_score_gemma":0.00023792712,"threshold_uncertainty_score":0.99999547},"labels":[],"label_agreement":null},{"id":"W2621176886","doi":"10.1038/cddis.2017.234","title":"Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Wound healing; Disease; Medicine; Skin repair; Cancer research; Cell biology; Endocrinology; Bioinformatics; Pathology; Internal medicine; Biology; Surgery","score_opus":0.014840207089095264,"score_gpt":0.2473381772973641,"score_spread":0.23249797020826884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2621176886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98454374,0.014187112,0.000026490276,0.00025814658,0.00008178702,0.0002634804,0.00009644627,0.000012683789,0.0005301225],"genre_scores_gemma":[0.9976086,0.001068835,0.0000615404,0.0004972666,0.00017323911,0.000028699307,0.00014010299,0.000017184211,0.00040451626],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989258,0.00006578497,0.00016745758,0.00045886362,0.000058403482,0.00032369938],"domain_scores_gemma":[0.99891156,0.000026104773,0.00007782864,0.00038816384,0.000036295784,0.00056005426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014097261,0.00019999183,0.00017561666,0.00004283674,0.00029932265,0.000118058975,0.00014892133,0.00010729521,0.000010117522],"category_scores_gemma":[0.0002206054,0.00018470437,0.00006474875,0.000015956479,0.00019484958,0.000012702548,0.000185619,0.00008594765,0.0000028724303],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017291844,0.00028794378,0.9434797,0.00065457454,0.000044166394,0.00021303738,0.00023755281,0.000007811942,0.04952103,0.0012336891,0.00056780706,0.0020235104],"study_design_scores_gemma":[0.003199202,0.00027145352,0.9714804,0.00009710231,0.00011689865,0.000009084537,0.00021395733,0.00065287587,0.0075545087,0.0019954187,0.0137100415,0.000699006],"about_ca_topic_score_codex":0.00015701851,"about_ca_topic_score_gemma":0.000119113385,"teacher_disagreement_score":0.04196652,"about_ca_system_score_codex":0.0000069173743,"about_ca_system_score_gemma":0.00011970999,"threshold_uncertainty_score":0.75320256},"labels":[],"label_agreement":null},{"id":"W2727317740","doi":"10.1038/cddis.2017.288","title":"KDM2B, an H3K36-specific demethylase, regulates apoptotic response of GBM cells to TRAIL","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Weill Cornell Medical College; Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu","keywords":"Demethylase; Gene knockdown; Epigenetics; Apoptosis; Biology; RNA interference; DNA methylation; Cancer research; Cell biology; Programmed cell death; Gene silencing; Downregulation and upregulation; Gene expression; RNA; Gene; Genetics","score_opus":0.014995660139147667,"score_gpt":0.25401529490567837,"score_spread":0.2390196347665307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2727317740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971452,0.0017782545,0.00028151678,0.000080792925,0.0000880038,0.0002675137,0.00013007782,0.000010940528,0.00021771585],"genre_scores_gemma":[0.99789566,0.00011417895,0.00079355255,0.00010120907,0.00011949993,0.000015189854,0.00009370033,0.000025794883,0.0008412304],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889785,0.00010066588,0.0001992139,0.00044744392,0.00012444022,0.00023036511],"domain_scores_gemma":[0.99794924,0.000017170485,0.00012030605,0.00100122,0.00008527247,0.00082676514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020170293,0.00017645789,0.00015064051,0.000055523087,0.0001898604,0.000072014795,0.0002659602,0.00009030856,0.000040127365],"category_scores_gemma":[0.00016678583,0.00017529404,0.000090319605,0.000030737465,0.00011947864,0.0000128864995,0.000120765595,0.000031538228,0.000010963529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024115983,0.00018385037,0.002299592,0.000065968365,0.000012057887,0.000010360209,0.000032886936,0.00007448289,0.9924811,0.000050938488,0.0014546169,0.0009225183],"study_design_scores_gemma":[0.0007701539,0.00025923792,0.18595998,0.000022622526,0.000055286837,0.0000011079976,0.000023041945,0.00008831855,0.80326545,0.00025881254,0.009043421,0.0002525434],"about_ca_topic_score_codex":0.000006680866,"about_ca_topic_score_gemma":0.0000023964092,"teacher_disagreement_score":0.18921565,"about_ca_system_score_codex":0.000010072631,"about_ca_system_score_gemma":0.00011944639,"threshold_uncertainty_score":0.7148284},"labels":[],"label_agreement":null},{"id":"W2734770601","doi":"10.1038/cddis.2017.306","title":"p75NTR antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; Ministerio de Economía y Competitividad; Ministerio de Educación, Cultura y Deporte","keywords":"Retinitis pigmentosa; Photoreceptor cell; Retina; Outer nuclear layer; Retinal; Biology; Retinal degeneration; Cell biology; Gene therapy of the human retina; Programmed cell death; TUNEL assay; Retinal regeneration; Apoptosis; Neuroscience; Biochemistry","score_opus":0.010849110580917904,"score_gpt":0.2342472090009752,"score_spread":0.2233980984200573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2734770601","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98594844,0.0013774349,0.000077391254,0.000106293024,0.000070823015,0.0001641028,0.000056892877,0.0000041646463,0.01219448],"genre_scores_gemma":[0.9961235,0.0019449875,0.0002153864,0.00010548326,0.000039191757,0.000016286634,0.0001615202,0.000013571354,0.0013800799],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919534,0.000020760814,0.00017244428,0.00029688768,0.00009895151,0.00021559557],"domain_scores_gemma":[0.9992462,0.0000047292046,0.00010840517,0.00033540424,0.00003574546,0.0002695407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007283558,0.00014466143,0.0001357947,0.000031622676,0.000105007945,0.00003803117,0.00017583056,0.00006096918,0.00003057301],"category_scores_gemma":[0.000037033293,0.00013934105,0.000057869325,0.000017888846,0.00010837226,0.000010084633,0.0001395114,0.000041425363,0.00000519095],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017903876,0.0005834977,0.834021,0.00057965284,0.00002345756,0.00014156626,0.00017774261,0.000055172615,0.15753722,0.00017567129,0.003352883,0.0015617721],"study_design_scores_gemma":[0.009764366,0.00048191758,0.48310903,0.00017199038,0.000114923816,0.0000054959664,0.00020321466,0.0012197748,0.4838481,0.004509922,0.015246309,0.0013249592],"about_ca_topic_score_codex":0.00005883562,"about_ca_topic_score_gemma":0.000008239649,"teacher_disagreement_score":0.35091195,"about_ca_system_score_codex":0.0000051052816,"about_ca_system_score_gemma":0.00009840109,"threshold_uncertainty_score":0.56821626},"labels":[],"label_agreement":null},{"id":"W2735492323","doi":"10.1038/cddis.2017.317","title":"Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Alberta","keywords":"Autophagy; ATG5; CD34; Myeloid leukemia; Cancer research; Gene knockdown; Programmed cell death; Biology; Apoptosis; Leukemia; Haematopoiesis; Myeloid; Stem cell; Cell biology; Immunology; Biochemistry","score_opus":0.02661531188400139,"score_gpt":0.3091838362297483,"score_spread":0.2825685243457469,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2735492323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921438,0.0026609222,0.00005767566,0.00011656065,0.00008167914,0.0005868772,0.0001234441,0.000032702017,0.0041963],"genre_scores_gemma":[0.9942205,0.0011844385,0.00009814361,0.00032101056,0.00014300438,0.00005792503,0.00018275583,0.000019737136,0.0037724809],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992473,0.000011304382,0.00016206491,0.00025153917,0.00011127727,0.00021649821],"domain_scores_gemma":[0.99872863,0.000021213684,0.00011889636,0.0004401479,0.000072765055,0.00061836373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003830293,0.00016677212,0.00025906862,0.00004425804,0.0002206398,0.00003718504,0.000053998723,0.00006289974,0.000106576175],"category_scores_gemma":[0.0000383846,0.00013148435,0.00014206616,0.000022354132,0.00008473904,0.00010513059,0.00002095678,0.000035967656,0.000017274258],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.10229972,0.012551883,0.12403559,0.0058393516,0.004388256,0.008782592,0.0030981167,0.00016302332,0.38719407,0.037779562,0.012495865,0.30137196],"study_design_scores_gemma":[0.043547574,0.009580028,0.4898542,0.0004410826,0.0060999836,0.000045088702,0.00025333988,0.0030687624,0.3947865,0.041836794,0.009507867,0.0009787895],"about_ca_topic_score_codex":0.000066877314,"about_ca_topic_score_gemma":0.00000124582,"teacher_disagreement_score":0.36581862,"about_ca_system_score_codex":0.000063599146,"about_ca_system_score_gemma":0.00063160976,"threshold_uncertainty_score":0.53617764},"labels":[],"label_agreement":null},{"id":"W2735513607","doi":"10.1038/cddis.2017.319","title":"An autocrine inflammatory forward-feedback loop after chemotherapy withdrawal facilitates the repopulation of drug-resistant breast cancer cells","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Health Canada; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Autocrine signalling; Paracrine signalling; Cancer research; Wnt signaling pathway; Cancer cell; Cancer stem cell; Biology; Breast cancer; Cancer; Immunology; Signal transduction; Medicine; Cell biology; Internal medicine; Receptor","score_opus":0.005856021594193643,"score_gpt":0.23476962053229633,"score_spread":0.22891359893810267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2735513607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98583245,0.012821756,0.000014939876,0.00040273578,0.00022827613,0.0003121886,0.0002605331,0.000027511209,0.00009962597],"genre_scores_gemma":[0.99467146,0.00078425434,0.000011344734,0.0001859967,0.00002916554,0.000062361105,0.000036586764,0.00001954894,0.0041992613],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99898607,0.00014854604,0.00028109804,0.00026742794,0.000048381637,0.00026850458],"domain_scores_gemma":[0.9987918,0.00004927933,0.00022597342,0.0007813421,0.00007747232,0.000074101976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016686937,0.00020628552,0.00022475826,0.0000447338,0.0004927823,0.00006262167,0.00027076484,0.00007710059,0.00045069386],"category_scores_gemma":[0.000020220768,0.00013925131,0.000107636,0.000024371268,0.00043409306,0.00023453245,0.000047978447,0.00011751442,0.000023008559],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019507794,0.00033361334,0.1433838,0.0001982028,0.00017505234,0.000018784865,0.0013968805,0.000019433131,0.82481223,0.00010347493,0.00065514917,0.00939557],"study_design_scores_gemma":[0.0020880138,0.000083429564,0.8958842,0.00006170716,0.00008648727,0.0000055116093,0.00020190277,0.000032753782,0.096532635,0.00018712021,0.004614261,0.00022199156],"about_ca_topic_score_codex":0.00045595007,"about_ca_topic_score_gemma":0.00002467959,"teacher_disagreement_score":0.7525004,"about_ca_system_score_codex":0.000018545761,"about_ca_system_score_gemma":0.00013995972,"threshold_uncertainty_score":0.56785035},"labels":[],"label_agreement":null},{"id":"W2742567781","doi":"10.1038/cddis.2017.366","title":"Uev1A facilitates osteosarcoma differentiation by promoting Smurf1-mediated Smad1 ubiquitination and degradation","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; Capital Normal University","keywords":"Osteosarcoma; Ubiquitin ligase; Ubiquitin; Cancer research; Suppressor; Stem cell; Effector; Carcinogenesis; Cell growth; Biology; Metastasis; Signal transduction; Cell; Cell biology; Gene; Cancer; Biochemistry; Genetics","score_opus":0.009342789207855012,"score_gpt":0.23036917963158765,"score_spread":0.22102639042373265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2742567781","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99609643,0.0027213523,0.0004865254,0.00014185072,0.00004070595,0.00020338691,0.00015048108,0.000020748565,0.00013854592],"genre_scores_gemma":[0.99749696,0.000105959465,0.000110652625,0.000065151355,0.000054471497,0.000028698862,0.0017632964,0.000013348093,0.0003614838],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99922204,0.000057139834,0.0001412359,0.0003194533,0.00009909153,0.00016106626],"domain_scores_gemma":[0.99914426,0.00002163351,0.00012480866,0.0003191944,0.00005690803,0.00033319162],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000102852806,0.00013499775,0.000082438724,0.000024124098,0.00035784184,0.00015893682,0.00012466466,0.000064101056,0.000008754612],"category_scores_gemma":[0.0007647335,0.00013117986,0.000031030326,0.00001187198,0.0000693075,0.000019342604,0.0001223773,0.00003684741,0.0000035245814],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017898675,0.0002111274,0.34440935,0.000293139,0.000023611903,0.0000052821397,0.000110222776,0.0000021027722,0.64205724,0.000040038627,0.0007086024,0.011960316],"study_design_scores_gemma":[0.0023385873,0.00022213678,0.7175681,0.000072306306,0.00015637626,0.0000019814272,0.00009612842,0.0036541973,0.27151424,0.0012008443,0.0026067903,0.0005682914],"about_ca_topic_score_codex":0.000012677643,"about_ca_topic_score_gemma":0.000003996526,"teacher_disagreement_score":0.37315878,"about_ca_system_score_codex":0.0000065094073,"about_ca_system_score_gemma":0.000045512865,"threshold_uncertainty_score":0.5349359},"labels":[],"label_agreement":null},{"id":"W2753109313","doi":"10.1038/cddis.2017.440","title":"Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers","year":2017,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":373,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"King Saud University","keywords":"Breast cancer; microRNA; Medicine; Oncology; Cancer; Biomarker; Biology; Internal medicine; Bioinformatics; Computational biology; Cancer research; Genetics; Gene","score_opus":0.02979799242428465,"score_gpt":0.3029843469793503,"score_spread":0.2731863545550656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2753109313","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.018193988,0.9798584,0.000021740538,0.00002492946,0.00008786653,0.0008185021,0.0009009089,0.000009097243,0.00008455988],"genre_scores_gemma":[0.03170865,0.9669037,0.000056170225,0.000036198762,0.00018507538,0.00019090979,0.00080895505,0.00005389756,0.00005644268],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985082,0.000060531365,0.00032845102,0.0007006084,0.00009043439,0.00031178823],"domain_scores_gemma":[0.9986112,0.00006666836,0.00027609678,0.0004587479,0.00003810478,0.00054917793],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010600138,0.00038994852,0.0005157254,0.00010041049,0.00013066379,0.00010683018,0.00017512137,0.00022333639,0.000008826335],"category_scores_gemma":[0.00034075722,0.00036359567,0.00016443079,0.000054096567,0.000117074465,0.0000074764803,0.00020133404,0.000101087615,0.0000028240372],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011771806,0.000402008,0.064947404,0.04476582,0.00029570592,0.00031304607,0.000019274157,0.000007595879,0.0022226775,0.00002275115,0.00074782694,0.8861382],"study_design_scores_gemma":[0.0030925036,0.00007018965,0.20579094,0.026420843,0.0043727616,0.00034664513,0.000016620219,0.00020207302,0.000044099572,0.000113489215,0.756907,0.0026228495],"about_ca_topic_score_codex":0.000053199674,"about_ca_topic_score_gemma":0.000008978233,"teacher_disagreement_score":0.8835153,"about_ca_system_score_codex":0.000037018017,"about_ca_system_score_gemma":0.00055051135,"threshold_uncertainty_score":0.9998816},"labels":[],"label_agreement":null},{"id":"W2756640516","doi":"10.1038/cddis.2017.450","title":"Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Priority Academic Program Development of Jiangsu Higher Education Institutions; Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Deubiquitinating enzyme; Ubiquitin; Apoptosis; Transcription factor; Gene knockdown; Biology; Cell biology; Cancer research; Chemistry; Genetics; Gene","score_opus":0.012593941225085909,"score_gpt":0.23083563747644967,"score_spread":0.21824169625136375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2756640516","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960317,0.0004815174,0.00014111049,0.00024808766,0.00003313561,0.000465532,0.00008162649,0.000005261283,0.0025120417],"genre_scores_gemma":[0.99826163,0.000049448117,0.0002529092,0.00024140305,0.00007070401,0.000060678267,0.00004407496,0.000011594401,0.0010075283],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993572,0.000040673294,0.00011504683,0.00025136973,0.00008850583,0.00014720268],"domain_scores_gemma":[0.999159,0.0000043606046,0.00010121099,0.00040111513,0.00004830883,0.00028603125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009028612,0.000116885596,0.00008479645,0.00001967906,0.00027632224,0.00005886996,0.000110357556,0.000062650084,0.00000830676],"category_scores_gemma":[0.00012649702,0.00009252536,0.000049035505,0.000020368361,0.000083383515,0.000008795513,0.00018432413,0.000042774664,0.0000031450677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019004139,0.00006184692,0.014628488,0.00016771373,0.0000027297247,0.0000014228476,0.00003705133,0.0000012284045,0.982832,0.00014253783,0.00022134268,0.0017135596],"study_design_scores_gemma":[0.00046530427,0.00014329492,0.02053509,0.000042361993,0.000027007876,6.93981e-7,0.000024090048,0.000014877079,0.97732,0.0002886559,0.001010712,0.00012787351],"about_ca_topic_score_codex":0.000019557052,"about_ca_topic_score_gemma":0.000007042835,"teacher_disagreement_score":0.005906601,"about_ca_system_score_codex":0.0000042492347,"about_ca_system_score_gemma":0.00006725579,"threshold_uncertainty_score":0.37730747},"labels":[],"label_agreement":null},{"id":"W2761656877","doi":"10.1038/cddis.2017.458","title":"BCR–ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Sociedade Beneficente Israelita Brasileira Albert Einstein; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Canadian Institutes of Health Research; Cancer Research Society; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; University of Toronto; Fundação de Amparo à Pesquisa do Estado de São Paulo; Natural Sciences and Engineering Research Council of Canada; Princess Margaret Cancer Foundation","keywords":"Myeloid leukemia; Cancer research; Biology; K562 cells; Carcinogenesis; breakpoint cluster region; Haematopoiesis; Tyrosine kinase; Chronic myelogenous leukemia; DNA methylation; Leukemia; Immunology; Signal transduction; Cell biology; Stem cell; Cancer; Gene expression; Genetics; Gene","score_opus":0.02783287584222453,"score_gpt":0.28518667046715124,"score_spread":0.2573537946249267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2761656877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923079,0.0059532365,0.00008178879,0.00036868016,0.000035241585,0.0007819087,0.000025888854,0.000016264097,0.00042908377],"genre_scores_gemma":[0.998537,0.0006540154,0.00014167817,0.00009007673,0.000050553877,0.00007039432,0.00007449161,0.0000157482,0.0003660114],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99898946,0.00002706145,0.00026186276,0.0003532535,0.00013510474,0.00023324664],"domain_scores_gemma":[0.9987727,0.000039424474,0.0001322774,0.0005463474,0.00006105903,0.0004482314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010074131,0.00016765251,0.0002814195,0.00012386632,0.00012312017,0.000039069095,0.00008170747,0.000078128236,0.000015427318],"category_scores_gemma":[0.0001948008,0.00015202502,0.00004024372,0.000058348778,0.000069349604,0.00010534404,0.0000660853,0.00006289754,0.0000085314405],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001111839,0.0002915134,0.5681022,0.0014142777,0.000068319576,0.00009557634,0.00041706042,0.00017725986,0.39294577,0.0012057668,0.00017556324,0.03399486],"study_design_scores_gemma":[0.005093423,0.00016379655,0.9633148,0.0002991148,0.00016242026,0.0000015907503,0.000027917884,0.002969072,0.026830038,0.00090940174,0.000097409196,0.00013106997],"about_ca_topic_score_codex":0.00037440078,"about_ca_topic_score_gemma":0.000050194863,"teacher_disagreement_score":0.39521256,"about_ca_system_score_codex":0.0006771311,"about_ca_system_score_gemma":0.0008127323,"threshold_uncertainty_score":0.61994004},"labels":[],"label_agreement":null},{"id":"W2763811454","doi":"10.1038/cddis.2017.481","title":"STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Shantou University Medical College; National Natural Science Foundation of China; Shantou University","keywords":"STAT1; Cancer research; Western blot; Biology; Immunohistochemistry; Esophageal cancer; Cancer; Phosphorylation; Immunology; Cell biology; Gene; Biochemistry","score_opus":0.018692154489802833,"score_gpt":0.2600153846943686,"score_spread":0.24132323020456575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2763811454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99452996,0.0014399395,0.0016558106,0.000108500084,0.00018449055,0.00042025014,0.00021984204,0.00003475185,0.0014064622],"genre_scores_gemma":[0.9978621,0.000026515456,0.0001833267,0.0001372136,0.00014082476,0.000049708684,0.00032956307,0.000019239438,0.0012515094],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990156,0.00004258629,0.00021510804,0.00034449282,0.00015955632,0.00022263589],"domain_scores_gemma":[0.99901956,0.00006858421,0.00015045756,0.00030564558,0.000051242863,0.00040453495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000097130665,0.00015600231,0.00017103464,0.000070589165,0.0003811366,0.00013050612,0.00006167879,0.00004514736,0.00017652017],"category_scores_gemma":[0.00017833049,0.00014245595,0.00005402065,0.000034348235,0.000036746354,0.0002700936,0.000033441884,0.00021698614,0.000018130657],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030792726,0.0013214892,0.5579224,0.00053492223,0.000016756738,0.00038704844,0.0012394979,0.000028299566,0.4224474,0.00004292793,0.0026244533,0.010355513],"study_design_scores_gemma":[0.006168141,0.0009341497,0.7496098,0.000115879855,0.00031351452,0.000003133372,0.00070669205,0.00451338,0.23371327,0.00079550274,0.0026951309,0.0004313896],"about_ca_topic_score_codex":0.0021092365,"about_ca_topic_score_gemma":0.00006316235,"teacher_disagreement_score":0.19168742,"about_ca_system_score_codex":0.00006291651,"about_ca_system_score_gemma":0.000190936,"threshold_uncertainty_score":0.5809185},"labels":[],"label_agreement":null},{"id":"W2764033835","doi":"10.1038/cddis.2017.437","title":"AP4 modulated by the PI3K/AKT pathway promotes prostate cancer proliferation and metastasis of prostate cancer via upregulating L-plastin","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Specialized Research Fund for the Doctoral Program of Higher Education of China; Fundamental Research Funds for the Central Universities; National Natural Science Foundation of China; Sun Yat-sen University; Natural Science Foundation of Guangdong Province; Public Health Agency of Canada","keywords":"Prostate cancer; Cancer research; LNCaP; Metastasis; Downregulation and upregulation; PI3K/AKT/mTOR pathway; Protein kinase B; Biology; Transcription factor; Prostate; Cancer; Signal transduction; Cell biology; Gene","score_opus":0.02161331577784226,"score_gpt":0.29566746641721225,"score_spread":0.27405415063937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2764033835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9787954,0.016756624,0.000014079973,0.0018948399,0.0000585096,0.0017520195,0.0005182467,0.000027163911,0.00018308169],"genre_scores_gemma":[0.99410987,0.0019128541,0.000067286215,0.00007727313,0.00006829658,0.0004653291,0.00012314349,0.000028567505,0.0031473832],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986871,0.000054635075,0.0002387641,0.000388297,0.0002857297,0.00034551256],"domain_scores_gemma":[0.99873924,0.000035420548,0.00020227258,0.0003558357,0.00018545524,0.0004817972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016437912,0.00022271705,0.0002795225,0.000046118614,0.0005507163,0.00013120851,0.00008681043,0.00004766884,0.000044230375],"category_scores_gemma":[0.000089718706,0.00013271366,0.000052075342,0.00006664294,0.00025952162,0.00020308756,0.00009155002,0.00012612593,0.0000011723799],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031400032,0.00037351483,0.8204796,0.0018240516,0.00022991991,0.00006258835,0.001842305,0.000046514146,0.06869294,0.000022535196,0.00062158366,0.10266445],"study_design_scores_gemma":[0.014552911,0.0009961938,0.6108883,0.001213062,0.0014812091,0.000014452971,0.0003171693,0.031371944,0.33533362,0.0012742012,0.001804538,0.0007524123],"about_ca_topic_score_codex":0.0005639905,"about_ca_topic_score_gemma":0.000037294623,"teacher_disagreement_score":0.26664066,"about_ca_system_score_codex":0.00004626159,"about_ca_system_score_gemma":0.00036948902,"threshold_uncertainty_score":0.54119056},"labels":[],"label_agreement":null},{"id":"W2765429845","doi":"10.1038/cddis.2017.482","title":"Metformin ameliorates arsenic trioxide hepatotoxicity via inhibiting mitochondrial complex I","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Changjiang Scholar Program of Chinese Ministry of Education; Foundation for Innovative Research Groups of the National Natural Science Foundation of China; Major Research Plan; National Natural Science Foundation of China","keywords":"Metformin; Arsenic trioxide; Pharmacology; Reactive oxygen species; Mitochondrion; Programmed cell death; Mitochondrial ROS; Mitochondrial respiratory chain; Apoptosis; Intracellular; Chemistry; Cancer research; Biology; Biochemistry; Diabetes mellitus; Endocrinology","score_opus":0.017708926221928073,"score_gpt":0.2592083778945364,"score_spread":0.2414994516726083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765429845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99254835,0.002199648,0.0017315843,0.000049182487,0.00013400547,0.0001921622,0.000032555636,0.00001736293,0.0030951423],"genre_scores_gemma":[0.99700916,0.00040573956,0.0008917832,0.00018821009,0.00044923168,0.000025130226,0.00014808631,0.000021903807,0.00086073694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894094,0.000035176276,0.00019180856,0.00042213596,0.00012061195,0.00028932618],"domain_scores_gemma":[0.99881995,0.000011917995,0.00015660089,0.00048952387,0.000062277126,0.00045975935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008672447,0.00020233978,0.00016911632,0.000026352436,0.0004881531,0.000163309,0.00022817412,0.00010493217,0.000026190895],"category_scores_gemma":[0.00027000534,0.00018498304,0.0001103227,0.000023004124,0.00015924085,0.000014117887,0.0002038055,0.000085128806,0.000013986558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032852349,0.00008095956,0.015112216,0.00012542511,0.000016864462,0.00005672395,0.000017815428,0.0000050517992,0.98075664,0.000062701896,0.0010052974,0.0024317543],"study_design_scores_gemma":[0.002160382,0.00019011703,0.0077297245,0.00003389396,0.00011112208,0.00001805036,0.00006132148,0.00077345077,0.9746724,0.0019077548,0.011785037,0.0005567791],"about_ca_topic_score_codex":0.0000312651,"about_ca_topic_score_gemma":0.000004802597,"teacher_disagreement_score":0.010779739,"about_ca_system_score_codex":0.000009592485,"about_ca_system_score_gemma":0.00015326249,"threshold_uncertainty_score":0.754339},"labels":[],"label_agreement":null},{"id":"W2772426563","doi":"10.1038/s41419-017-0074-8","title":"In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Simon Fraser University; McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Retinitis pigmentosa; MAPK/ERK pathway; Tumor necrosis factor alpha; Medicine; Cell biology; Biology; Neuroscience; Signal transduction; Immunology; Retina","score_opus":0.011003858087987957,"score_gpt":0.2487197657803288,"score_spread":0.23771590769234086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2772426563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947174,0.0003750084,0.00008526185,0.00014266635,0.00044332954,0.0002277,0.00003316818,0.00001010916,0.003965314],"genre_scores_gemma":[0.9984533,0.00019066861,0.00005789634,0.00011198782,0.00039284327,0.000023500812,0.000059572623,0.00001957038,0.00069064496],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99879557,0.00006319626,0.0001399226,0.00049645774,0.00016630706,0.00033852377],"domain_scores_gemma":[0.9992142,0.000014585418,0.00010049361,0.00028607366,0.000041360938,0.0003433207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009938832,0.00021881732,0.00015957857,0.000041067346,0.00032600373,0.00014607575,0.00013696546,0.00010371627,0.000024862838],"category_scores_gemma":[0.00019033933,0.00021938993,0.00007417919,0.000025889718,0.00007487197,0.000024078676,0.0001756006,0.000104496954,0.0000044992594],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0067803306,0.0006431249,0.7397719,0.0001546766,0.00007554664,0.0003738545,0.00023019066,0.00006041338,0.24616538,0.00024445684,0.0020996728,0.003400428],"study_design_scores_gemma":[0.0033586957,0.00025515287,0.8952464,0.00003064977,0.00007185154,0.0000058727373,0.000025946789,0.00019000324,0.09710498,0.0013307862,0.0018328575,0.0005468114],"about_ca_topic_score_codex":0.00014604439,"about_ca_topic_score_gemma":0.000048587288,"teacher_disagreement_score":0.15547447,"about_ca_system_score_codex":0.00002379445,"about_ca_system_score_gemma":0.00022833014,"threshold_uncertainty_score":0.89464617},"labels":[],"label_agreement":null},{"id":"W2772434918","doi":"10.1038/s41419-017-0050-3","title":"Pyridoxine 5′-phosphate oxidase is a novel therapeutic target and regulated by the TGF-β signalling pathway in epithelial ovarian cancer","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"National Natural Science Foundation of China; Science and Technology Commission of Shanghai Municipality; Natural Science Foundation of Shanghai","keywords":"Gene knockdown; Cancer research; Cell growth; Carcinogenesis; Internal medicine; Endocrinology; Medicine; Chemistry; Apoptosis; Cancer; Biochemistry","score_opus":0.012361818812709147,"score_gpt":0.24184678992741054,"score_spread":0.2294849711147014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2772434918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9724022,0.025647638,0.00038673577,0.0007005954,0.000074719406,0.000261547,0.0004319514,0.000012101582,0.00008252007],"genre_scores_gemma":[0.99738544,0.00039015387,0.00007266306,0.0012880695,0.00012593418,0.000052716652,0.00009457402,0.000028806557,0.00056162954],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989283,0.000036483398,0.00017754777,0.00044622738,0.00011556918,0.00029585423],"domain_scores_gemma":[0.9989887,0.000017773573,0.00011628696,0.00046385685,0.000030643187,0.00038274503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013039082,0.00021805323,0.00014713695,0.000021488997,0.00035431626,0.00014619697,0.00024401209,0.0000892444,0.00003950287],"category_scores_gemma":[0.000066603105,0.0001642744,0.000058520665,0.00002803449,0.00016935338,0.000011521503,0.00012939554,0.00008351488,0.0000016917325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008902649,0.0002960603,0.03557269,0.00010068535,0.000066804416,0.00002753508,0.00015642702,0.00017468836,0.95885533,0.00005876164,0.0008458227,0.002954913],"study_design_scores_gemma":[0.0059478823,0.00014964813,0.12203596,0.00013861143,0.00017236073,0.0000038950266,0.000059147995,0.0055360305,0.8288203,0.0009963317,0.03527789,0.0008619798],"about_ca_topic_score_codex":0.00017657818,"about_ca_topic_score_gemma":0.0000136436765,"teacher_disagreement_score":0.13003509,"about_ca_system_score_codex":0.000009193735,"about_ca_system_score_gemma":0.00017581033,"threshold_uncertainty_score":0.66989154},"labels":[],"label_agreement":null},{"id":"W2789900485","doi":"10.1038/s41419-017-0230-1","title":"Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; China Scholarship Council","keywords":"Downregulation and upregulation; Cell biology; Trophoblast; Biology; Cadherin; Gene knockdown; Small interfering RNA; Bone morphogenetic protein 2; SMAD; Cell migration; Signal transduction; Cell culture; Cancer research; Cell; Transfection; Biochemistry; Placenta; Genetics; In vitro","score_opus":0.00820389845976187,"score_gpt":0.22111162478900262,"score_spread":0.21290772632924074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2789900485","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944166,0.003067373,0.001432212,0.000016367454,0.000043648575,0.0005655905,0.00005012866,0.000035998135,0.00037207338],"genre_scores_gemma":[0.9966621,0.000010941339,0.0013990605,0.00013356292,0.00039486075,0.000091024,0.00028318234,0.000065554996,0.00095974695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813485,0.00009987877,0.00034652543,0.0007380702,0.00021254261,0.00046811515],"domain_scores_gemma":[0.9984359,0.000014715517,0.0001408431,0.00047318728,0.00008962167,0.0008457018],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001324999,0.00033330504,0.0002158408,0.000043387096,0.0004034939,0.000084916326,0.00021173009,0.0001521228,0.000112666865],"category_scores_gemma":[0.00007408089,0.00032817974,0.000119619544,0.00007785629,0.00020711466,0.000008817308,0.00021732484,0.00011623393,0.000032060798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022943049,0.0003337073,0.005030473,0.00019826142,0.000013182964,0.000021334505,0.00003555816,0.000025218758,0.99315196,0.0000019190275,0.0005754318,0.00038351965],"study_design_scores_gemma":[0.0011785373,0.0005748705,0.0027366667,0.00008838834,0.00007814583,0.0000029616083,0.000023875566,0.0005144137,0.9932656,0.00012404053,0.00095639715,0.00045606555],"about_ca_topic_score_codex":0.000026563986,"about_ca_topic_score_gemma":0.0000048157635,"teacher_disagreement_score":0.0030564317,"about_ca_system_score_codex":0.000017795372,"about_ca_system_score_gemma":0.00020196318,"threshold_uncertainty_score":0.99991703},"labels":[],"label_agreement":null},{"id":"W2790332513","doi":"10.1038/s41419-018-0311-9","title":"CFTR mutation enhances Dishevelled degradation and results in impairment of Wnt-dependent hematopoiesis","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Institutes of Health; Sichuan University; Southwest University; Chinese University of Hong Kong; China Postdoctoral Science Foundation; Chengdu Medical College; Tsinghua University; National Natural Science Foundation of China; McGill University","keywords":"Wnt signaling pathway; Zebrafish; Cell biology; Cystic fibrosis transmembrane conductance regulator; Haematopoiesis; Biology; Dishevelled; Cystic fibrosis; Mutation; Mutant; Signal transduction; Cancer research; Frizzled; Genetics; Stem cell; Gene","score_opus":0.012215975179455205,"score_gpt":0.28878405477992153,"score_spread":0.2765680796004663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790332513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969115,0.0015121306,0.00033027836,0.00026746636,0.000026489393,0.00036120912,0.000034664063,0.000011175319,0.00054504327],"genre_scores_gemma":[0.9981249,0.00024371358,0.0011180121,0.000033065047,0.00003344325,0.00002183941,0.000051991075,0.0000058438995,0.00036718222],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991197,0.000031287538,0.00024951927,0.00021997598,0.00022769385,0.00015181629],"domain_scores_gemma":[0.9993102,0.00009256959,0.00006792745,0.000121960205,0.00007213544,0.00033521978],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016946421,0.000084305226,0.0001500593,0.00009609255,0.00004095502,0.000015975995,0.000028000633,0.000022367854,0.000027925103],"category_scores_gemma":[0.00047052465,0.00006752139,0.000020386422,0.00009099585,0.00010822927,0.000100298945,0.000033782817,0.00003822971,0.0000042665206],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.05906398,0.0046788924,0.53467274,0.008985255,0.00013985253,0.00075392966,0.0071482854,0.000022200182,0.30548853,0.0011168177,0.0027762614,0.07515326],"study_design_scores_gemma":[0.007949423,0.001332522,0.86523765,0.00042325456,0.00010876189,0.000011760145,0.00094811537,0.0019344564,0.11846971,0.0031696581,0.00020845761,0.0002062459],"about_ca_topic_score_codex":0.00007144375,"about_ca_topic_score_gemma":0.000034499986,"teacher_disagreement_score":0.3305649,"about_ca_system_score_codex":0.000028073124,"about_ca_system_score_gemma":0.00010203139,"threshold_uncertainty_score":0.27534422},"labels":[],"label_agreement":null},{"id":"W2791307733","doi":"10.1038/s41419-017-0115-3","title":"BIM and NOXA are mitochondrial effectors of TAF6δ-driven apoptosis","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Université de Sherbrooke; Centre National de la Recherche Scientifique; Sidaction","keywords":"Biology; Effector; Cell biology; Programmed cell death; Transcriptome; Apoptosis; Transcription factor; Mitochondrion; Gene; Gene expression; Mitochondrial DNA; Genetics","score_opus":0.007203512837240126,"score_gpt":0.2231447843554699,"score_spread":0.21594127151822975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791307733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979059,0.0011357763,0.00020517694,0.000030216412,0.000151429,0.00010222705,0.00005395456,0.000004482644,0.0004108504],"genre_scores_gemma":[0.99877095,0.00030379294,0.00016798827,0.00016834136,0.0002945171,0.00000855408,0.000039445065,0.000008202622,0.00023822307],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994673,0.000022298309,0.00009294363,0.00023775146,0.000053538057,0.00012617055],"domain_scores_gemma":[0.9994667,0.0000074407626,0.00004677554,0.00017375103,0.000054640277,0.00025069487],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000018732862,0.000103719874,0.000102448386,0.000027105063,0.00004892687,0.00001498503,0.000065309214,0.00006118316,0.000020503543],"category_scores_gemma":[0.000044461944,0.000089901856,0.000049572427,0.000026249274,0.000109610526,0.0000033220151,0.00007289648,0.00002461968,0.000005547138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005981106,0.00009416957,0.11244537,0.00011430742,0.00003209522,0.0000036440283,0.000039163846,0.0000021565363,0.88103175,0.000023405177,0.004726509,0.0008893394],"study_design_scores_gemma":[0.001444034,0.00096757035,0.05582132,0.000060046506,0.00013578331,0.0000018468724,0.00008278053,0.00017333975,0.9366025,0.00016071566,0.004231458,0.00031865586],"about_ca_topic_score_codex":0.000015847836,"about_ca_topic_score_gemma":0.00000536873,"teacher_disagreement_score":0.056624055,"about_ca_system_score_codex":0.0000018555494,"about_ca_system_score_gemma":0.00003290335,"threshold_uncertainty_score":0.36660916},"labels":[],"label_agreement":null},{"id":"W2792021782","doi":"10.1038/s41419-017-0033-4","title":"Redox crosstalk at endoplasmic reticulum (ER) membrane contact sites (MCS) uses toxic waste to deliver messages","year":2018,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Associazione Italiana per la Ricerca sul Cancro; Ministero della Salute; Canadian Institutes of Health Research; Fondazione Cariplo","keywords":"Endoplasmic reticulum; Cell biology; Peroxisome; Mitochondrion; Redox; Reactive oxygen species; SERCA; Chemistry; Uniporter; Biochemistry; Biology; Receptor; Cytosol; Enzyme; ATPase","score_opus":0.0216617194654777,"score_gpt":0.2749998342807571,"score_spread":0.2533381148152794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792021782","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.040169924,0.95570755,0.00005099533,0.000023309307,0.0006125077,0.00075649703,0.00067025033,0.000028252864,0.0019807154],"genre_scores_gemma":[0.002919805,0.9787405,0.00012593645,0.00068554166,0.00090392877,0.00011728365,0.001644807,0.00007085729,0.014791339],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.997821,0.00020917862,0.00041396174,0.0009695267,0.00014552225,0.0004408622],"domain_scores_gemma":[0.9980127,0.000052798878,0.00017596617,0.00069458585,0.0000911546,0.0009727749],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000110028726,0.00054008735,0.00076361245,0.00010022373,0.0002043294,0.000078997014,0.0002356762,0.00039701734,0.0005169766],"category_scores_gemma":[0.00025325437,0.00044426665,0.00041382315,0.00009220135,0.000106395084,0.000006966529,0.00033433095,0.00013038446,0.0003166746],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0061982856,0.001308033,0.0016477001,0.054362234,0.0013719602,0.002107734,0.0003268847,0.00001926579,0.29566544,0.00041262465,0.56212676,0.074453086],"study_design_scores_gemma":[0.00055801537,0.00033030158,0.000014936461,0.00051421416,0.0006670575,0.000055299897,0.000011593697,0.0000022377897,0.0071982555,0.0000113909555,0.9900943,0.0005423669],"about_ca_topic_score_codex":0.0000079189795,"about_ca_topic_score_gemma":0.000023789182,"teacher_disagreement_score":0.42796758,"about_ca_system_score_codex":0.000025333358,"about_ca_system_score_gemma":0.00018918721,"threshold_uncertainty_score":0.9998009},"labels":[],"label_agreement":null},{"id":"W2792216524","doi":"10.1038/s41419-017-0194-1","title":"Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β production","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Necroptosis; Proteasome; Programmed cell death; Apoptosis; Stimulation; Biology; Proteasome inhibitor; Caspase; Secretion; TLR4; Cancer research; Cell biology; Pharmacology; Immune system; Immunology; Endocrinology; Biochemistry","score_opus":0.006459460001927147,"score_gpt":0.2137107622920743,"score_spread":0.20725130229014715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792216524","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99512184,0.0033483948,0.00035407455,0.00013895564,0.00011391293,0.0005381148,0.000010308174,0.00001710948,0.00035726317],"genre_scores_gemma":[0.9956365,0.002068786,0.00033472435,0.00008663547,0.00031548546,0.000041425432,0.000094444586,0.000019813715,0.0014021776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908984,0.00003710463,0.00011800443,0.00046301584,0.000114158254,0.00017785955],"domain_scores_gemma":[0.9993962,0.0000038272433,0.00007938241,0.00016120294,0.000090886824,0.00026850385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095424104,0.00018061417,0.00010874322,0.00004163726,0.00023190495,0.000070497306,0.000038309732,0.00007943988,0.00000570901],"category_scores_gemma":[0.000013910704,0.00013913689,0.000023471717,0.000048143036,0.00011787556,0.00001816461,0.000039422557,0.000044690627,0.0000016165884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060235744,0.00022701008,0.010565299,0.00013611371,0.000013286654,0.0000053164104,0.00012880392,0.000002725653,0.9817633,0.00022353638,0.00016678056,0.006165451],"study_design_scores_gemma":[0.0017815058,0.0013566111,0.06026622,0.000041748957,0.0000586278,0.0000137315765,0.00007811238,0.0002478299,0.9290832,0.0013598532,0.005334539,0.00037800663],"about_ca_topic_score_codex":0.000014384446,"about_ca_topic_score_gemma":0.000005761474,"teacher_disagreement_score":0.052680105,"about_ca_system_score_codex":0.000006634477,"about_ca_system_score_gemma":0.00006245892,"threshold_uncertainty_score":0.56738377},"labels":[],"label_agreement":null},{"id":"W2792265734","doi":"10.1038/s41419-018-0304-8","title":"Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":203,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fundação para a Ciência e a Tecnologia; Harvard University; Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University; Institute for Bioengineering and Biosciences; U.S. Food and Drug Administration; Hamilton Health Sciences Foundation","keywords":"Apoptosis; Acute Radiation Syndrome; Countermeasure; Programmed cell death; Cell biology; Cytotoxicity; Tight junction; In vitro; Cancer research; Medicine; Biology; Stem cell; Materials science; Biochemistry","score_opus":0.019112593268276957,"score_gpt":0.2869585175391128,"score_spread":0.2678459242708358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792265734","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962483,0.0010954617,0.000041072366,0.000309289,0.0000844093,0.00052196684,0.000031440362,0.000057631973,0.0016104241],"genre_scores_gemma":[0.99788046,0.00009410106,0.00007190997,0.0010839088,0.0002758866,0.00002809719,0.000042683834,0.000031125892,0.000491799],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987111,0.00012696718,0.00023365518,0.0004061772,0.00025490197,0.0002672067],"domain_scores_gemma":[0.9987882,0.000090272406,0.00006247404,0.0003074292,0.000087709544,0.0006639372],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003195611,0.00021273032,0.00023289643,0.00024421513,0.00017457407,0.000056091263,0.000059819224,0.00008763122,0.000023171453],"category_scores_gemma":[0.00027941004,0.00019643553,0.0000472947,0.00010300707,0.000042137304,0.00013738668,0.000025552194,0.00017714806,0.000017752933],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0103711,0.0012412134,0.8721308,0.0011669879,0.000043652304,0.00035165934,0.0033298754,0.00024557256,0.102794394,0.00064593775,0.0028097297,0.004869078],"study_design_scores_gemma":[0.016827801,0.00286146,0.8268403,0.0006425676,0.00054643437,0.000014182389,0.0003931094,0.13015737,0.017331084,0.0022900263,0.00096791424,0.0011278029],"about_ca_topic_score_codex":0.0000699867,"about_ca_topic_score_gemma":0.000012365896,"teacher_disagreement_score":0.1299118,"about_ca_system_score_codex":0.00006722035,"about_ca_system_score_gemma":0.0001911041,"threshold_uncertainty_score":0.8010409},"labels":[],"label_agreement":null},{"id":"W2792317071","doi":"10.1038/s41419-018-0360-0","title":"Ceramide-induced BOK promotes mitochondrial fission in preeclampsia","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Mitochondrial fission; MFN2; DNM1L; Mitochondrion; Mitophagy; Cell biology; FIS1; mitochondrial fusion; PINK1; Biology; MFN1; Autophagy; Programmed cell death; Apoptosis; Mitochondrial DNA; Genetics; Gene","score_opus":0.01355765017148677,"score_gpt":0.24973063010853522,"score_spread":0.23617297993704844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792317071","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933202,0.0004014531,0.00039414444,0.00012474383,0.000634166,0.00027323788,0.000013754345,0.000014825726,0.004823472],"genre_scores_gemma":[0.99602956,0.000054562344,0.00047017066,0.00039731903,0.0009486048,0.000027362323,0.000104553736,0.000014358441,0.0019535406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912715,0.00006895548,0.00014159748,0.00038295917,0.00006769026,0.00021164306],"domain_scores_gemma":[0.99931616,0.00000791028,0.00003575524,0.00025225288,0.000037818525,0.00035011437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000046827685,0.00013242527,0.000101626494,0.000044529505,0.00007697345,0.000023039642,0.00007684035,0.00013113196,0.00010736486],"category_scores_gemma":[0.0001549012,0.000118388256,0.000047722406,0.000053101514,0.00005289513,0.000004511727,0.000066570145,0.00006446551,0.000034810957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009937498,0.0001384845,0.017317872,0.000031196723,0.000005774168,0.000023429226,0.000061685074,9.655487e-7,0.97564185,0.000121410834,0.004537986,0.0011256132],"study_design_scores_gemma":[0.010460785,0.003489278,0.11827567,0.000108037035,0.00015384582,0.000038714545,0.00016653763,0.00080219435,0.6964042,0.004553254,0.16406848,0.001479],"about_ca_topic_score_codex":0.00001404925,"about_ca_topic_score_gemma":0.000021763635,"teacher_disagreement_score":0.27923763,"about_ca_system_score_codex":0.0000058431247,"about_ca_system_score_gemma":0.00010450383,"threshold_uncertainty_score":0.4827733},"labels":[],"label_agreement":null},{"id":"W2792423424","doi":"10.1038/s41419-018-0349-8","title":"DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Department of Science and Technology of Sichuan Province; University of Waterloo; National Natural Science Foundation of China","keywords":"EZH2; Biology; Histone H3; Histone methylation; PI3K/AKT/mTOR pathway; Histone; Retinal degeneration; Cell biology; Retina; Epigenetics; Retinitis pigmentosa; Cancer research; DNA methylation; Signal transduction; Genetics; Gene expression; Gene; Neuroscience","score_opus":0.0060898381079137805,"score_gpt":0.2138004343977935,"score_spread":0.20771059628987973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792423424","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99444103,0.0017694583,0.00036864134,0.00020163615,0.000027068674,0.00012139171,0.0000040475074,0.0000034654756,0.0030632298],"genre_scores_gemma":[0.9982521,0.00033177232,0.0002281841,0.00080856646,0.000100523175,0.000014017471,0.00013178472,0.0000051402967,0.00012791385],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995025,0.00004148643,0.000085227606,0.00019311042,0.00006162382,0.00011606398],"domain_scores_gemma":[0.99975264,0.0000057344064,0.00002208339,0.00008430083,0.000027281245,0.000107983964],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008914831,0.00008147638,0.000041694973,0.000021006885,0.00010583574,0.000039721777,0.000043297707,0.0000427077,0.000005168419],"category_scores_gemma":[0.00003172741,0.000063044834,0.000016130218,0.000039923758,0.00005594687,0.000005608679,0.000030025452,0.000029413812,0.000005046772],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013744367,0.00014943784,0.27519965,0.00013334665,0.000010640109,0.00002980517,0.00085825723,0.0000059694153,0.7110749,0.0008263834,0.006158845,0.004178325],"study_design_scores_gemma":[0.004355437,0.0011504462,0.48894182,0.0000879743,0.0001605528,0.000054628672,0.0011040588,0.0016020039,0.48329502,0.0037907765,0.014375022,0.0010822508],"about_ca_topic_score_codex":0.000010769054,"about_ca_topic_score_gemma":0.000035975514,"teacher_disagreement_score":0.22777988,"about_ca_system_score_codex":0.0000028295333,"about_ca_system_score_gemma":0.000040847168,"threshold_uncertainty_score":0.25708938},"labels":[],"label_agreement":null},{"id":"W2792465576","doi":"10.1038/s41419-018-0282-x","title":"Long non-coding RNAs in ischemic stroke","year":2018,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":295,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"MEG3; Biology; MALAT1; Long non-coding RNA; Neurogenesis; Gene; Gene expression; Angiogenesis; DNA methylation; Non-coding RNA; Cancer research; RNA; Bioinformatics; Genetics","score_opus":0.01993955462998347,"score_gpt":0.30560479660548817,"score_spread":0.2856652419755047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792465576","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002013272,0.99187094,0.0029300242,0.0000048263882,0.00012668996,0.00058464287,0.000110689965,0.000008483604,0.00416236],"genre_scores_gemma":[0.0019248993,0.99432135,0.00007140103,0.00006277094,0.00034129308,0.00011892094,0.0005626367,0.00007136618,0.002525374],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982507,0.00007604639,0.00029840478,0.00073461706,0.00017936836,0.00046083707],"domain_scores_gemma":[0.9986767,0.00001287791,0.00010267965,0.00054456596,0.000043003573,0.000620156],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015591316,0.00036462548,0.00050209684,0.00015637782,0.00006309922,0.00005730827,0.0002784495,0.0003686041,0.000041814477],"category_scores_gemma":[0.00008142224,0.0003445434,0.0002895466,0.00012329243,0.00006511525,0.0000034167333,0.00031632298,0.00028555334,0.000050300176],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044997458,0.00047541654,0.000085051695,0.04666777,0.0003688764,0.0011269448,0.0000347798,0.000007638475,0.018179063,0.000039588827,0.023362199,0.9092027],"study_design_scores_gemma":[0.0005312939,0.00008684578,0.000005887003,0.0018454319,0.00025386363,0.000012758369,0.000004368047,0.000029902838,0.004236431,0.000009495161,0.9925354,0.0004482889],"about_ca_topic_score_codex":0.000013147875,"about_ca_topic_score_gemma":0.000008262764,"teacher_disagreement_score":0.96917325,"about_ca_system_score_codex":0.000051607498,"about_ca_system_score_gemma":0.00072211976,"threshold_uncertainty_score":0.99990064},"labels":[],"label_agreement":null},{"id":"W2792497119","doi":"10.1038/s41419-018-0411-6","title":"Rb is required for retinal angiogenesis and lamination","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ocular Oncology and Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Krembil Foundation; National Natural Science Foundation of China; Foundation Fighting Blindness","keywords":"Retina; Retinoblastoma; Lamination; Cell biology; Biology; Angiogenesis; HIF1A; E2F1; Cell cycle; Retinal; Muller glia; Neovascularization; Cancer research; Neuroscience; Chemistry; Cell; Stem cell; Genetics; Progenitor cell; Biochemistry","score_opus":0.018504610069218975,"score_gpt":0.2883639900460772,"score_spread":0.2698593799768582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792497119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99526405,0.0017291446,0.00022491204,0.00067654415,0.00004347461,0.0002443296,0.000030223708,0.000014533024,0.0017727973],"genre_scores_gemma":[0.9952892,0.00008582353,0.0007545529,0.00070419884,0.00011645937,0.000021295076,0.000050821818,0.0000060828843,0.0029715493],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99965924,0.000009427744,0.000052378982,0.00014656551,0.00004006661,0.00009230386],"domain_scores_gemma":[0.99959093,0.000019782576,0.000017890567,0.00008143388,0.00004323145,0.00024672],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003982069,0.000058373847,0.00007624681,0.000027365168,0.00009042013,0.000006257059,0.00001020431,0.000035960296,0.000034490156],"category_scores_gemma":[0.000044226283,0.00004782598,0.00003146157,0.000023914474,0.000061791005,0.000029172423,0.000009876315,0.000010419147,0.000010996047],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002540673,0.0004890201,0.9626631,0.00034173983,0.00008418718,0.00014633634,0.00032885864,1.3860525e-8,0.0016585458,0.00084181107,0.0059404164,0.024965312],"study_design_scores_gemma":[0.0065319194,0.001353352,0.9668369,0.000047362555,0.0012723458,0.00001634616,0.0000613974,0.00055092835,0.006476461,0.002510127,0.014190455,0.00015238301],"about_ca_topic_score_codex":0.000002763564,"about_ca_topic_score_gemma":5.950176e-7,"teacher_disagreement_score":0.02481293,"about_ca_system_score_codex":0.000008775102,"about_ca_system_score_gemma":0.000039264447,"threshold_uncertainty_score":0.19502869},"labels":[],"label_agreement":null},{"id":"W2792684603","doi":"10.1038/s41419-017-0108-2","title":"Identification of microRNA signature in the progression of gestational trophoblastic disease","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Gestational Trophoblastic Disease Studies","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Science and Technology Commission of Shanghai Municipality; Queen's University; National Natural Science Foundation of China; Shanghai Municipal Health and Family Planning Commission; University of Pittsburgh","keywords":"Choriocarcinoma; microRNA; Trophoblast; Cancer research; Gestational trophoblastic disease; Carcinogenesis; Biology; Metastasis; SOX2; Oncology; Medicine; Cancer; Internal medicine; Pregnancy; Placenta; Gene; Gestation; Embryonic stem cell; Fetus; Genetics","score_opus":0.010355000414129796,"score_gpt":0.27432101315364305,"score_spread":0.26396601273951326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792684603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963791,0.0019645304,0.00022650942,0.0005410137,0.000047672525,0.00040347336,0.00015413537,0.0000072978864,0.00027630516],"genre_scores_gemma":[0.99935097,0.00005940701,0.00017992388,0.00013933454,0.00006120892,0.000037061636,0.00007608619,0.000007839811,0.00008818598],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990529,0.000046368452,0.00027103905,0.00018643163,0.00032945917,0.000113828675],"domain_scores_gemma":[0.9990847,0.00014199167,0.00012756266,0.00017215115,0.00022654097,0.00024705252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009163078,0.00010023002,0.00013275324,0.00009131489,0.00005277397,0.0000079820675,0.000063633495,0.000020753376,0.000032796313],"category_scores_gemma":[0.0004967675,0.000067376095,0.000053203406,0.00015546811,0.00025647023,0.00004405966,0.00002263279,0.00005602944,0.0000064734145],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016170321,0.00620993,0.79167974,0.0063728127,0.00012192145,0.00039928692,0.003295484,0.00014679352,0.15533906,0.012512584,0.004592057,0.0031600061],"study_design_scores_gemma":[0.0010980607,0.00015352336,0.99416095,0.0001757278,0.000233552,0.0000010779484,0.00020278057,0.0006385112,0.00085880206,0.0023420334,0.00006908938,0.00006588673],"about_ca_topic_score_codex":0.000002358221,"about_ca_topic_score_gemma":5.515052e-7,"teacher_disagreement_score":0.20248121,"about_ca_system_score_codex":0.00000914386,"about_ca_system_score_gemma":0.00023936424,"threshold_uncertainty_score":0.27475172},"labels":[],"label_agreement":null},{"id":"W2793230550","doi":"10.1038/s41419-018-0364-9","title":"MTSS1 and SCAMP1 cooperate to prevent invasion in breast cancer","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"John and Lucille Van Geest Foundation; European Commission; Trent University; Nottingham Trent University","keywords":"Cell biology; Cell adhesion; Biology; Extracellular matrix; Cancer cell; Cell; Cell adhesion molecule; Cell membrane; Cancer; Cancer research; Biochemistry","score_opus":0.008201316392758508,"score_gpt":0.23913433669007622,"score_spread":0.23093302029731771,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793230550","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963879,0.002556872,0.000047250964,0.00033534356,0.0000774935,0.00014033479,0.000029756326,0.000004890984,0.00042013582],"genre_scores_gemma":[0.99619365,0.00093780574,0.00013104394,0.0011894051,0.00016522483,0.000043560067,0.000028007436,0.000009979348,0.0013013197],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99940383,0.00001742229,0.00008790919,0.0002767702,0.000054982982,0.0001590766],"domain_scores_gemma":[0.99951375,0.0000024239105,0.000016528851,0.00010397411,0.000044724464,0.00031859078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006121638,0.00009935486,0.000070306,0.000027425422,0.0000510211,0.000025549267,0.00005452804,0.00004104324,0.0000688059],"category_scores_gemma":[0.000010728217,0.0000866558,0.000014058375,0.00005328838,0.000042464064,0.0000036475237,0.00009071239,0.000025641744,0.000008462666],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014468629,0.0002697161,0.54124296,0.00016043366,0.000029618575,0.000024586707,0.00032264853,0.000082098704,0.421213,0.000058582726,0.024363976,0.010785498],"study_design_scores_gemma":[0.0027308387,0.00033272416,0.7119488,0.00026930912,0.000079303565,0.000011090378,0.000096172014,0.00030577715,0.24141864,0.00041758694,0.041404538,0.0009852065],"about_ca_topic_score_codex":0.000036561658,"about_ca_topic_score_gemma":0.000029964473,"teacher_disagreement_score":0.17979434,"about_ca_system_score_codex":0.000009223363,"about_ca_system_score_gemma":0.00012575444,"threshold_uncertainty_score":0.35337207},"labels":[],"label_agreement":null},{"id":"W2793683521","doi":"10.1038/s41419-018-0326-2","title":"Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Jewish General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"mTORC1; Downregulation and upregulation; eIF2; PI3K/AKT/mTOR pathway; Integrated stress response; Cell biology; Oxidative stress; Unfolded protein response; Biology; TSC2; Endoplasmic reticulum; Signal transduction; Translation (biology); Endocrinology; Biochemistry; Messenger RNA; Gene","score_opus":0.011657568096053433,"score_gpt":0.232353002314003,"score_spread":0.22069543421794957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793683521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956688,0.0029274307,0.000605618,0.000035714576,0.000018949324,0.00052464765,0.00011034064,0.000007484032,0.000101003505],"genre_scores_gemma":[0.9990492,0.00032412016,0.00024761359,0.00005347789,0.00005260424,0.000054883643,0.00011450597,0.000011309359,0.000092302704],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992639,0.000035905763,0.00012919886,0.00033053284,0.00007974386,0.00016074504],"domain_scores_gemma":[0.9994794,0.000012100381,0.000067146524,0.00018219084,0.000043189528,0.00021596461],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000072816656,0.00013942148,0.00013962966,0.000032753484,0.00008095112,0.00002179223,0.00004334786,0.00005681437,0.0000029529294],"category_scores_gemma":[0.00002281178,0.00012702397,0.000021863645,0.0000634222,0.00009877898,0.000009570337,0.00006111292,0.000032965552,9.3691665e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016076773,0.00019464242,0.01133424,0.0001240765,0.0000045641777,4.5910147e-7,0.00004109017,0.0000046981545,0.984054,0.000072587776,0.00011898154,0.003889881],"study_design_scores_gemma":[0.0007234575,0.00014146847,0.5117383,0.000016614977,0.000033054435,0.0000010420174,0.0000065003746,0.0010662293,0.4856197,0.00006819196,0.00046678953,0.000118653006],"about_ca_topic_score_codex":0.0000712849,"about_ca_topic_score_gemma":0.000007928735,"teacher_disagreement_score":0.50040406,"about_ca_system_score_codex":0.0000058529035,"about_ca_system_score_gemma":0.000032903605,"threshold_uncertainty_score":0.51798874},"labels":[],"label_agreement":null},{"id":"W2799443762","doi":"10.1038/s41419-018-0601-2","title":"CD47-ligation induced cell death in T-acute lymphoblastic leukemia","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; BC Children's Hospital","keywords":"CD47; Programmed cell death; Apoptosis; Monoclonal antibody; Cell; Immunogenicity; Epitope; Cancer research; Biology; Cell biology; Antibody; Chemistry; Immunology; Biochemistry","score_opus":0.012920211593202079,"score_gpt":0.23139101794890593,"score_spread":0.21847080635570384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2799443762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943723,0.002032171,0.00015385884,0.00003582805,0.00030107427,0.00019606765,0.000020435498,0.000039549785,0.0028487283],"genre_scores_gemma":[0.9979056,0.00012556622,0.000036129462,0.00020838008,0.000048473536,0.000021079513,0.00017740385,0.000015043542,0.0014622931],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99903476,0.00008252956,0.00023039457,0.0003124066,0.00003370271,0.0003062086],"domain_scores_gemma":[0.99949586,0.000038616567,0.00008180099,0.00022806243,0.000044673885,0.00011096125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000085703556,0.00017421642,0.00018259633,0.00011205736,0.00016100518,0.000025784962,0.00009759332,0.00014793254,0.00015442027],"category_scores_gemma":[0.000032163236,0.00015955683,0.000053889915,0.000108146676,0.00007931198,0.000146026,0.00005930824,0.000095867064,0.00031254036],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006888154,0.00023861702,0.05350401,0.00006122956,0.000031479485,0.000018713294,0.00032159247,0.00000825423,0.9406002,0.00061247026,0.001089538,0.0028250464],"study_design_scores_gemma":[0.004279539,0.00031945566,0.7012497,0.00006215351,0.00017111287,0.000009162528,0.000059740083,0.0006621646,0.28884935,0.0012763939,0.0026635944,0.00039764252],"about_ca_topic_score_codex":0.00009138538,"about_ca_topic_score_gemma":0.0000057402685,"teacher_disagreement_score":0.6517509,"about_ca_system_score_codex":0.000102492384,"about_ca_system_score_gemma":0.00022348846,"threshold_uncertainty_score":0.6506539},"labels":[],"label_agreement":null},{"id":"W2801326259","doi":"10.1038/s41419-018-0531-z","title":"Hepatic steatosis associated with decreased β-oxidation and mitochondrial function contributes to cell damage in obese mice after thermal injury","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; Sunnybrook Hospital","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Steatosis; Liver injury; Internal medicine; Endocrinology; Medicine; Lipolysis; Mitochondrion; Homeostasis; Adipose tissue; Biology","score_opus":0.003061908114005463,"score_gpt":0.19865809672045082,"score_spread":0.19559618860644534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801326259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99777937,0.0010208621,0.00030110273,0.0000452446,0.00006452948,0.0003394232,0.000126509,0.000010225235,0.00031271222],"genre_scores_gemma":[0.99855554,0.000054142285,0.00005768257,0.0006578828,0.00010512489,0.00008757847,0.00027992408,0.000016420687,0.00018572189],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99911034,0.00007542918,0.00013886561,0.00036244898,0.00009167231,0.0002212537],"domain_scores_gemma":[0.99919516,0.000020948992,0.000047796537,0.00017757011,0.00007687621,0.00048164185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004959026,0.00016711495,0.00012589812,0.000057147277,0.00007115415,0.00005658217,0.000049973383,0.00007767355,0.000021708245],"category_scores_gemma":[0.00013015998,0.0001411457,0.000032215758,0.00007949161,0.000074591495,0.000011777851,0.0000548982,0.00004234186,0.000005855392],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00866911,0.00042791912,0.64406157,0.000085523825,0.0000313651,0.000027664573,0.00005677483,0.000011520423,0.3454794,0.000008879803,0.00081366964,0.00032660295],"study_design_scores_gemma":[0.0045197746,0.0008439785,0.907195,0.00010018974,0.00026751688,3.78596e-7,0.00007708572,0.00041762483,0.08567236,0.000082032755,0.00045032127,0.0003737691],"about_ca_topic_score_codex":0.00004242168,"about_ca_topic_score_gemma":0.0000766561,"teacher_disagreement_score":0.26313338,"about_ca_system_score_codex":0.000013181874,"about_ca_system_score_gemma":0.000092439856,"threshold_uncertainty_score":0.5755755},"labels":[],"label_agreement":null},{"id":"W2801429094","doi":"10.1038/s41419-018-0522-0","title":"O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistance","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fundamental Research Funds for the Central Universities; Simon Fraser University; National Natural Science Foundation of China","keywords":"Cancer research; Cancer cell; Cancer; Doxorubicin; Camptothecin; Chemotherapy; Cell growth; Cell; Biology; Cell biology; Chemistry; Biochemistry; Genetics","score_opus":0.011807804623567557,"score_gpt":0.2595112513999335,"score_spread":0.2477034467763659,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801429094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99375564,0.0014237891,0.00071321795,0.00024806804,0.000061016184,0.00023519002,0.000040060186,0.000005165058,0.0035178536],"genre_scores_gemma":[0.99651474,0.0003990281,0.00012625755,0.00024306256,0.00014044641,0.000032939555,0.000036878264,0.000009421388,0.0024972386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932617,0.00003671176,0.000119037366,0.00022552388,0.00015047558,0.00014206088],"domain_scores_gemma":[0.9994192,0.000009142632,0.00007942423,0.00026025696,0.0001325379,0.00009939804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005662863,0.00009419793,0.000068851936,0.00001155108,0.000114850016,0.000014711576,0.000109879154,0.000051393,0.00009039562],"category_scores_gemma":[0.000082812934,0.0000682837,0.000044528948,0.000082065366,0.00012460073,0.000010066854,0.000056175115,0.00003455381,0.0000034663515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020561123,0.000082809194,0.0030796146,0.00009341722,0.000004814051,2.414472e-7,0.000046536592,0.0000042698803,0.99459624,0.00012494023,0.00049147324,0.0012700337],"study_design_scores_gemma":[0.00033930672,0.000067592235,0.011141518,0.000021963111,0.000009420774,1.2407436e-7,0.000034468678,0.00013258703,0.97838557,0.000252802,0.009527489,0.000087141416],"about_ca_topic_score_codex":0.00007869235,"about_ca_topic_score_gemma":0.000047064404,"teacher_disagreement_score":0.016210653,"about_ca_system_score_codex":0.000013537526,"about_ca_system_score_gemma":0.00016284791,"threshold_uncertainty_score":0.27845284},"labels":[],"label_agreement":null},{"id":"W2802245341","doi":"10.1038/s41419-018-0629-3","title":"Checkpoint suppressor 1 suppresses transcriptional activity of ERα and breast cancer cell proliferation via deacetylase SIRT1","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fundamental Research Funds for the Central Universities; Université de Montréal; Sungkyunkwan University; Dalian Medical University; National Natural Science Foundation of China","keywords":"Cancer research; Breast cancer; Estrogen receptor; Carcinogenesis; Transactivation; Sirtuin 1; Cancer; Estrogen receptor alpha; Biology; Cancer cell; Histone deacetylase; Cell growth; Transcription factor; Chemistry; Internal medicine; Medicine; Downregulation and upregulation; Histone; Biochemistry","score_opus":0.010657098623596538,"score_gpt":0.23454579195707304,"score_spread":0.2238886933334765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802245341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99480563,0.0026627646,0.0006743318,0.00012739055,0.000056458975,0.000247998,0.00069193856,0.00000838181,0.0007250845],"genre_scores_gemma":[0.9985835,0.00044201454,0.00012074241,0.0001358205,0.00024358921,0.000053924647,0.000096931144,0.000013466184,0.00030999095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999278,0.000046870595,0.00011510342,0.00029531613,0.00009575414,0.00016894078],"domain_scores_gemma":[0.99935704,0.000006885586,0.000054849246,0.00015845234,0.00009326399,0.00032949334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000064808555,0.00014065752,0.00011131566,0.000017258619,0.000092390896,0.000022915572,0.000056989724,0.00007690919,0.00015459902],"category_scores_gemma":[0.000013592529,0.00012761411,0.000050420505,0.000023945402,0.00012470105,0.000014401757,0.00004435596,0.000042644042,0.0000017154496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008941645,0.00022323722,0.0068533723,0.00026131008,0.000012159047,0.0000018087618,0.00008829807,0.0000021359178,0.990295,0.000028434564,0.00024577454,0.0010943196],"study_design_scores_gemma":[0.00087885594,0.00016865447,0.032448668,0.000015349637,0.000058032572,0.0000055508085,0.000016324184,0.00030514944,0.96485907,0.00012674036,0.00095585134,0.00016175522],"about_ca_topic_score_codex":0.000068283596,"about_ca_topic_score_gemma":0.00004592529,"teacher_disagreement_score":0.025595296,"about_ca_system_score_codex":0.0000060403045,"about_ca_system_score_gemma":0.00011840119,"threshold_uncertainty_score":0.5203953},"labels":[],"label_agreement":null},{"id":"W2802319445","doi":"10.1038/s41419-018-0544-7","title":"N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Vlaamse regering; Universiteit Gent; Fonds Wetenschappelijk Onderzoek; Institut National Du Cancer; Vlaams Instituut voor Biotechnologie; University of Toronto; Medical Research Council; Belgian Federal Science Policy Office","keywords":"Apoptosis; Ectodomain; Unfolded protein response; Tunicamycin; Cell biology; Endoplasmic reticulum; Programmed cell death; Cytotoxic T cell; Tumor necrosis factor alpha; Glycosylation; Caspase; Biology; Chemistry; Receptor; Immunology; Biochemistry; In vitro","score_opus":0.014002015819631371,"score_gpt":0.23722553914206057,"score_spread":0.2232235233224292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802319445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99584603,0.00029704292,0.001822478,0.00004661715,0.000088121174,0.00016663659,0.00004110842,0.00001172318,0.0016802322],"genre_scores_gemma":[0.9976902,0.0001594091,0.000415077,0.000095465184,0.00021609038,0.0000085488655,0.00016471109,0.000016491338,0.001233994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992755,0.000027257078,0.00016177917,0.0002735969,0.000101301295,0.00016057082],"domain_scores_gemma":[0.99933887,0.0000049643795,0.000068336085,0.00023350878,0.00007057727,0.00028376968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007147076,0.00012333338,0.00010103658,0.000041986597,0.00008439108,0.000015345335,0.00006548921,0.000099560566,0.00004004832],"category_scores_gemma":[0.00003526335,0.000112702524,0.00007374158,0.00005136158,0.000057570654,0.0000057136604,0.000030510366,0.000030614385,0.000005144892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001898328,0.00009150745,0.00077059027,0.000042902982,0.00001028122,8.05583e-7,0.000050972343,0.000006485464,0.99294335,0.00044101002,0.00022424049,0.0052280184],"study_design_scores_gemma":[0.0010114858,0.00048199194,0.020530885,0.000012979703,0.00007486213,0.0000012953775,0.000049680602,0.000596869,0.97283804,0.00069611665,0.0034660995,0.00023967007],"about_ca_topic_score_codex":0.000015622001,"about_ca_topic_score_gemma":0.000007743693,"teacher_disagreement_score":0.02010529,"about_ca_system_score_codex":0.000004748485,"about_ca_system_score_gemma":0.000072747316,"threshold_uncertainty_score":0.45958757},"labels":[],"label_agreement":null},{"id":"W2803033440","doi":"10.1038/s41419-018-0534-9","title":"HCC-derived exosomes elicit HCC progression and recurrence by epithelial-mesenchymal transition through MAPK/ERK signalling pathway","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":278,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Fonds de Recherche du Québec - Santé; Tianjin Medical University; National Natural Science Foundation of China","keywords":"Microvesicles; Exosome; Cancer research; Metastasis; Epithelial–mesenchymal transition; Biology; Gene knockdown; MAPK/ERK pathway; Cell migration; Cell; Cell biology; Cancer; Cell culture; microRNA; Signal transduction","score_opus":0.009349392731031528,"score_gpt":0.2470203419297727,"score_spread":0.23767094919874118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803033440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97335184,0.019861085,0.005466205,0.00013276601,0.00008292789,0.0003313288,0.00023050806,0.00003056256,0.00051278825],"genre_scores_gemma":[0.9961273,0.0013609426,0.0011967911,0.00041592744,0.00031235686,0.000038923223,0.0003386273,0.000029734021,0.0001793676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859416,0.00009047501,0.0002067975,0.00060809363,0.00016752323,0.0003329638],"domain_scores_gemma":[0.99900764,0.000015758167,0.000081006896,0.00024748413,0.00007835566,0.00056974526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010255254,0.00024985612,0.00016279878,0.00002416646,0.00023220423,0.00006763045,0.00012689173,0.00012798932,0.000034332348],"category_scores_gemma":[0.00006849807,0.00023026891,0.0000749102,0.00005853124,0.0002632687,0.000021848633,0.000085124484,0.00008333062,0.000011531099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048820028,0.00022529335,0.0011644342,0.00015376393,0.000014424838,0.00003140491,0.0002025416,0.000002289961,0.9906332,0.000058419486,0.00073929655,0.0062867436],"study_design_scores_gemma":[0.0015680179,0.00051489094,0.0019892047,0.00014445838,0.00010968458,0.000007332792,0.00012779549,0.00066075823,0.9845701,0.0019650222,0.0077762166,0.0005665192],"about_ca_topic_score_codex":0.0000055584483,"about_ca_topic_score_gemma":0.0000011911023,"teacher_disagreement_score":0.022775503,"about_ca_system_score_codex":0.000007892084,"about_ca_system_score_gemma":0.00010477027,"threshold_uncertainty_score":0.93900937},"labels":[],"label_agreement":null},{"id":"W2803164013","doi":"10.1038/s41419-018-0672-0","title":"Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; National Research Council Canada; Institute of Infection and Immunity; University of Ottawa","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institutes of Health Research; King Saud University","keywords":"Necroptosis; RIPK1; Ubiquitin ligase; Ubiquitin; Cell biology; Programmed cell death; Inflammation; Downregulation and upregulation; Cytokine; Biology; Signal transduction; Chemistry; Cancer research; Apoptosis; Biochemistry; Immunology","score_opus":0.013308980602955094,"score_gpt":0.23293312513272052,"score_spread":0.21962414452976542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803164013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997594,0.00078758923,0.0007094075,0.00029729787,0.00014001108,0.0002957446,0.000016051887,0.0000061268174,0.0001537951],"genre_scores_gemma":[0.99745256,0.00032192247,0.00020058737,0.000119938515,0.00023804209,0.000017331373,0.0000369329,0.000009767106,0.0016029059],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936306,0.000030228028,0.00012774214,0.00026682657,0.00009755103,0.00011461679],"domain_scores_gemma":[0.9994601,0.0000051779302,0.00006035493,0.00020832744,0.0000826149,0.00018341269],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011193756,0.000098645134,0.00007931976,0.00003492069,0.00013221259,0.00003301731,0.000056154724,0.00005421846,0.000009069993],"category_scores_gemma":[0.00007807154,0.00006980689,0.000030192703,0.000061585524,0.00006100169,0.000007882234,0.00006543624,0.00002778605,0.0000023395094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043746186,0.0000641889,0.004707517,0.000031965363,0.000012379965,5.7733615e-7,0.000078979116,0.000010315196,0.9869563,0.0001816819,0.00023688439,0.007281766],"study_design_scores_gemma":[0.0006843082,0.0008075241,0.11567553,0.000026281214,0.00012275185,0.0000035790092,0.000097616496,0.00008284047,0.8786386,0.0005288251,0.0031106588,0.00022144275],"about_ca_topic_score_codex":0.000033386088,"about_ca_topic_score_gemma":0.00000932633,"teacher_disagreement_score":0.11096801,"about_ca_system_score_codex":0.0000041351987,"about_ca_system_score_gemma":0.000037225967,"threshold_uncertainty_score":0.28466424},"labels":[],"label_agreement":null},{"id":"W2803650666","doi":"10.1038/s41419-018-0607-9","title":"Tamoxifen-induced knockdown of the mitochondrial calcium uniporter in Thy1-expressing neurons protects mice from hypoxic/ischemic brain injury","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Dalhousie University","funders":"Multiple Sclerosis Society; Multiple Sclerosis Society of Canada; Heart and Stroke Foundation of Canada; European Genomic Institute for Diabetes; Fondation Brain Canada; National Institute of General Medical Sciences; American Heart Association","keywords":"Uniporter; Gene knockdown; Neuroprotection; Mitochondrion; Gene silencing; Biology; Forebrain; Programmed cell death; Neuroscience; Cell biology; Apoptosis; Cytosol; Biochemistry; Central nervous system; Gene","score_opus":0.015571404660379344,"score_gpt":0.2470274699721221,"score_spread":0.23145606531174276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803650666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99678195,0.00030301826,0.00036146844,0.00023481765,0.00072058727,0.0003766186,0.000101333375,0.000008843522,0.0011113812],"genre_scores_gemma":[0.9970544,0.00001239268,0.0002396304,0.0011474281,0.0007304507,0.00003149659,0.00007136593,0.00001866691,0.0006941448],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998883,0.00015063737,0.0002206725,0.00042068644,0.0000966211,0.0002283763],"domain_scores_gemma":[0.9991587,0.000023356444,0.000102466955,0.00043271505,0.000048628433,0.00023416655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053513977,0.00016911904,0.000148468,0.000038611204,0.000090154856,0.000019159306,0.00017562674,0.00015882414,0.000056978162],"category_scores_gemma":[0.0002640729,0.00013283514,0.00008671659,0.00008375719,0.00012883559,0.0000066068847,0.00015406258,0.00012871667,0.000007513869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006934968,0.00007897844,0.0037658461,0.000017550034,0.000006177452,0.0000055759497,0.00008060516,0.0000013696406,0.9902511,0.0000057259404,0.0047018416,0.00039169632],"study_design_scores_gemma":[0.001327827,0.00020508672,0.00929702,0.000032361146,0.000035436664,0.000002575532,0.000029429206,0.000056803357,0.96938235,0.00023108361,0.019192155,0.00020787254],"about_ca_topic_score_codex":0.00007573552,"about_ca_topic_score_gemma":0.000031136628,"teacher_disagreement_score":0.02086879,"about_ca_system_score_codex":0.000006421736,"about_ca_system_score_gemma":0.00018599343,"threshold_uncertainty_score":0.54168594},"labels":[],"label_agreement":null},{"id":"W2803755660","doi":"10.1038/s41419-018-0506-0","title":"Ferroptosis-inducing agents compromise in vitro human islet viability and function","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":176,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Medical Association; Dalhousie University; University of Alberta","funders":"Alberta Innovates; Alberta Innovates - Health Solutions; Government of Canada","keywords":"Islet; Viability assay; Apoptosis; Transplantation; GPX4; Programmed cell death; Biology; In vivo; Oxidative stress; Immunology; Cancer research; Glutathione peroxidase; Endocrinology; Internal medicine; Biochemistry; Diabetes mellitus; Medicine; Superoxide dismutase","score_opus":0.02433115300317671,"score_gpt":0.26672766661888464,"score_spread":0.24239651361570794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803755660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991699,0.00031458915,0.00003474218,0.00011527321,0.00008727513,0.00025133838,0.000009053164,0.000036069498,0.007452674],"genre_scores_gemma":[0.99826944,0.0000103002085,0.00007492258,0.0007890831,0.00013086734,0.00001603234,0.00004177749,0.000008619212,0.00065895525],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99928164,0.000035298264,0.00014069246,0.0002768627,0.00009657989,0.00016892512],"domain_scores_gemma":[0.9991938,0.000027714623,0.00002830979,0.00018152426,0.000032940367,0.00053574936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010749148,0.00011069344,0.00017184517,0.000070513015,0.0001141148,0.000021950056,0.000018016959,0.000041131094,0.00019439794],"category_scores_gemma":[0.000104993705,0.00009514805,0.00003076439,0.00006776975,0.0000885126,0.000061657665,0.00002714714,0.0000688212,0.000020765725],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002065362,0.00058319065,0.79203755,0.00045740794,0.000019541714,0.000025798372,0.00023134402,6.923006e-7,0.20063822,0.0000596882,0.0014724513,0.0024087352],"study_design_scores_gemma":[0.0040681143,0.00027705386,0.975137,0.000059751546,0.00019638955,0.0000016156004,0.00011138767,0.00196604,0.015742905,0.0007360286,0.0015467651,0.00015693695],"about_ca_topic_score_codex":0.000048748207,"about_ca_topic_score_gemma":0.0000010034371,"teacher_disagreement_score":0.18489532,"about_ca_system_score_codex":0.000027305776,"about_ca_system_score_gemma":0.000038104296,"threshold_uncertainty_score":0.38800249},"labels":[],"label_agreement":null},{"id":"W2804932513","doi":"10.1038/s41419-018-0639-1","title":"Correction to: Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice","year":2018,"lang":"en","type":"erratum","venue":"Cell Death and Disease","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Wound healing; Medicine; Bioinformatics; Pathology; Surgery; Biology","score_opus":0.010260492651858966,"score_gpt":0.23699130303588756,"score_spread":0.2267308103840286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2804932513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95104563,0.039029434,0.0000702477,0.00017756334,0.005991766,0.0008077547,0.00040588528,0.000038352508,0.002433387],"genre_scores_gemma":[0.9580329,0.003337196,0.000056702247,0.0013809352,0.0020472633,0.00010419445,0.002617844,0.00006580976,0.032357145],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979941,0.00015304994,0.00031686897,0.0009188852,0.000114368115,0.0005027124],"domain_scores_gemma":[0.9984123,0.000049043272,0.00011488602,0.00037319426,0.00010498367,0.00094560615],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001871755,0.00044736243,0.00037117052,0.00015455844,0.00018236304,0.000098268785,0.00015410851,0.00038311395,0.000025501773],"category_scores_gemma":[0.00038126402,0.0004357629,0.00012373521,0.000085630825,0.00016675123,0.000008461256,0.00022252026,0.00030087304,0.000009680492],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0041054017,0.00050648,0.054449975,0.0024075683,0.00013074148,0.000226479,0.00050591305,0.000012896536,0.009648985,0.00011510833,0.9259523,0.00193815],"study_design_scores_gemma":[0.003044887,0.0015002894,0.13038422,0.00096228014,0.0005073545,0.000028649145,0.00043698394,0.001431741,0.0024232469,0.000715043,0.856243,0.002322298],"about_ca_topic_score_codex":0.00026629382,"about_ca_topic_score_gemma":0.00046854618,"teacher_disagreement_score":0.075934246,"about_ca_system_score_codex":0.000029053142,"about_ca_system_score_gemma":0.00045124817,"threshold_uncertainty_score":0.99980944},"labels":[],"label_agreement":null},{"id":"W2811277922","doi":"10.1038/s41419-018-0780-x","title":"Nogo-A inactivation improves visual plasticity and recovery after retinal injury","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canada Foundation for Innovation; Velux Stiftung","keywords":"Retinal; Neuroscience; Electroretinography; Neuroplasticity; Retina; NMDA receptor; Optokinetic reflex; Retinal degeneration; Synaptic plasticity; Erg; Spontaneous recovery; Ophthalmology; Biology; Medicine; Eye movement; Internal medicine","score_opus":0.011087759491040532,"score_gpt":0.25105456501979634,"score_spread":0.2399668055287558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2811277922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984038,0.00007113847,0.00036161623,0.00007742577,0.00018806335,0.00011227788,0.00002990941,0.000026384892,0.0007294152],"genre_scores_gemma":[0.99824685,0.000045848745,0.000052216976,0.00075019285,0.0003285758,0.000014582294,0.000004238759,0.0000073978185,0.0005501147],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993162,0.000050972176,0.000098846154,0.00030049073,0.00009568442,0.00013778915],"domain_scores_gemma":[0.99955046,0.000054115455,0.00004073966,0.00007074338,0.000024319352,0.00025962142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000041837986,0.000097563134,0.00006493857,0.000044882257,0.000185833,0.00007917801,0.000031411564,0.00003840725,0.000029678275],"category_scores_gemma":[0.0002223586,0.00008082642,0.000019935926,0.00005954946,0.00013399917,0.00027742767,0.00004453713,0.00005650117,0.00001576935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025006942,0.0001150666,0.004700822,0.000058768717,0.0000011004578,0.000016399836,0.000047630037,3.3959327e-7,0.9861685,0.00037226715,0.00047090862,0.0055474886],"study_design_scores_gemma":[0.00035760578,0.0006804257,0.07660438,0.000021381951,0.00003008598,0.0000029861417,0.000010293868,0.0013978832,0.9180843,0.001911988,0.0007002933,0.00019832468],"about_ca_topic_score_codex":0.0000048567745,"about_ca_topic_score_gemma":0.0000011194655,"teacher_disagreement_score":0.07190356,"about_ca_system_score_codex":0.000010766613,"about_ca_system_score_gemma":0.000043117387,"threshold_uncertainty_score":0.32960057},"labels":[],"label_agreement":null},{"id":"W2883892389","doi":"10.1038/s41419-018-0811-7","title":"Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Health Canada; Institute of Infection and Immunity; University of Ottawa","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Huntsman Cancer Institute","keywords":"mTORC1; Triple-negative breast cancer; Cancer research; CD44; Cancer stem cell; Tamoxifen; Breast cancer; PI3K/AKT/mTOR pathway; Cancer; Carcinogenesis; Cancer cell; Estrogen receptor alpha; Biology; Estrogen receptor; Chemistry; Medicine; Signal transduction; Cell; Internal medicine; Cell biology","score_opus":0.009548659767529478,"score_gpt":0.25173667943744255,"score_spread":0.24218801966991307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883892389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98825026,0.009525039,0.00005815831,0.00011606292,0.00010626238,0.000206724,0.0014722447,0.0000042602114,0.00026100723],"genre_scores_gemma":[0.9963773,0.002881129,0.000024890991,0.0001695647,0.00021190157,0.000034309774,0.000019307708,0.000014105219,0.0002675272],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992398,0.000050103612,0.00015790561,0.00028609432,0.000114089606,0.00015199804],"domain_scores_gemma":[0.9993055,0.000025127045,0.00012173263,0.00017674724,0.0001750384,0.00019586402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008211237,0.00014148549,0.00015656822,0.00002306322,0.00008005692,0.0000161226,0.00006553691,0.0000685284,0.000043645236],"category_scores_gemma":[0.00001626527,0.000105191946,0.00004006658,0.000048080157,0.00048142043,0.000008539435,0.000049831775,0.000044488614,2.91198e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012541822,0.00007784466,0.06617253,0.00051525247,0.00008387486,0.0000032699604,0.00030428387,0.0000063209463,0.92447287,0.00007922419,0.00566908,0.0013612753],"study_design_scores_gemma":[0.0010144539,0.0001605664,0.022633981,0.00008208317,0.00014401069,0.0000018772178,0.00007765904,0.00006190535,0.974926,0.0002151021,0.00053250627,0.0001498885],"about_ca_topic_score_codex":0.00032864825,"about_ca_topic_score_gemma":0.00003810546,"teacher_disagreement_score":0.050453108,"about_ca_system_score_codex":0.000010425143,"about_ca_system_score_gemma":0.00017633008,"threshold_uncertainty_score":0.42896032},"labels":[],"label_agreement":null},{"id":"W2887076505","doi":"10.1038/s41419-018-0846-9","title":"ApoNETosis: discovery of a novel form of neutrophil death with concomitant apoptosis and NETosis","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Cystic Fibrosis Canada; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Apoptosis; Concomitant; Programmed cell death; Immunology; Cell biology; Biology; Medicine; Chemistry; Biochemistry; Internal medicine","score_opus":0.015271704733369019,"score_gpt":0.2186262897393293,"score_spread":0.20335458500596026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887076505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950519,0.002480201,0.0010549461,0.000075989046,0.0000840848,0.00027488405,0.00028463503,0.000018608098,0.0006747072],"genre_scores_gemma":[0.99860793,0.0003750489,0.00035873003,0.00023045119,0.000030508094,0.00002490368,0.00004933964,0.000020802994,0.00030226092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895716,0.000046674155,0.00027847395,0.000369465,0.00005120243,0.0002970452],"domain_scores_gemma":[0.9992181,0.000077157725,0.00016782481,0.0002911044,0.00010629806,0.00013951867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007566727,0.00024415247,0.00040713226,0.000104681276,0.00013284344,0.000016782607,0.00012264293,0.00009662983,0.00003922423],"category_scores_gemma":[0.000023266377,0.00017640625,0.000071442206,0.00010337778,0.00044178637,0.00018543284,0.00011251761,0.00009535629,0.00000572619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019700315,0.0004446951,0.01377081,0.0001870574,0.00014510217,0.0000041474814,0.00031176844,6.2364234e-7,0.9732075,0.009444838,0.00009117694,0.00042227693],"study_design_scores_gemma":[0.004630691,0.0015524274,0.026778026,0.00016346057,0.00047963893,0.000011234626,0.00029862934,0.000018740204,0.9644532,0.00082457036,0.00046342093,0.00032591503],"about_ca_topic_score_codex":0.00008684144,"about_ca_topic_score_gemma":0.000004587283,"teacher_disagreement_score":0.013007216,"about_ca_system_score_codex":0.000011028336,"about_ca_system_score_gemma":0.00009845091,"threshold_uncertainty_score":0.7193638},"labels":[],"label_agreement":null},{"id":"W2891242560","doi":"10.1038/s41419-018-0997-8","title":"Phosphoglycerate dehydrogenase inhibition induces p-mTOR-independent autophagy and promotes multilineage differentiation in embryonal carcinoma stem-like cells","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Capital District Health Authority; McMaster University; Dalhousie University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; QEII Foundation; Beatrice Hunter Cancer Research Institute; Cure Brain Cancer Foundation; Nova Scotia Health Research Foundation; Cancer Research Institute","keywords":"Biology; Cancer stem cell; Cancer research; Autophagy; Stem cell; Cellular differentiation; PI3K/AKT/mTOR pathway; Cancer cell; Cell biology; Homeobox protein NANOG; Apoptosis; Cancer; Embryonic stem cell; Signal transduction; Induced pluripotent stem cell; Biochemistry; Genetics; Gene","score_opus":0.010435819091240915,"score_gpt":0.22585623683921707,"score_spread":0.21542041774797616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891242560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955342,0.0036303543,0.00029010538,0.000013831519,0.00011708093,0.00026473496,0.000049484235,0.000008636165,0.00009161087],"genre_scores_gemma":[0.9988783,0.00028958768,0.000111661015,0.00007753354,0.0001435944,0.000022180006,0.00019671528,0.000016443195,0.0002639594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990179,0.00006289534,0.0001985018,0.00041145144,0.0001120763,0.00019717109],"domain_scores_gemma":[0.9993966,0.000009694751,0.000074449425,0.0001600829,0.00006004901,0.00029908956],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106582804,0.00016545333,0.000111177185,0.00005735563,0.0001004185,0.000055013435,0.000040551495,0.00011018442,0.000013438123],"category_scores_gemma":[0.000016877242,0.00015840691,0.00003583597,0.00004860095,0.000061024493,0.000010735842,0.000074007825,0.000058111025,0.0000038899275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020276212,0.00015256325,0.04363701,0.00006410085,0.000006394394,0.000014683202,0.00009282056,0.000009576081,0.954407,0.000015708789,0.00001607822,0.0013813246],"study_design_scores_gemma":[0.001046499,0.00017926985,0.15292728,0.000012089923,0.000024687284,6.653607e-7,0.000024729268,0.0025870171,0.84276044,0.00016067737,0.00010608173,0.00017053184],"about_ca_topic_score_codex":0.000037479105,"about_ca_topic_score_gemma":0.0000352762,"teacher_disagreement_score":0.11164651,"about_ca_system_score_codex":0.000012014083,"about_ca_system_score_gemma":0.00007375778,"threshold_uncertainty_score":0.6459646},"labels":[],"label_agreement":null},{"id":"W2891284575","doi":"10.1038/s41419-018-0954-6","title":"Regulation of cell surface protease receptor S100A10 by retinoic acid therapy in acute promyelocytic leukemia (APL)☆","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Dalhousie University; Dalhousie Medical Research Foundation; Breast Cancer Society of Canada; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Lactacystin; Retinoic acid; Ubiquitin; Downregulation and upregulation; Biology; Proteasome; Extracellular; Acute promyelocytic leukemia; Protein degradation; Retinoic acid receptor; Cell biology; Cell culture; Molecular biology; Proteasome inhibitor; Biochemistry","score_opus":0.005835145792690208,"score_gpt":0.22074825182106037,"score_spread":0.21491310602837016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891284575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99298024,0.0046476107,0.00029611145,0.000038333746,0.00006460326,0.0004995586,0.000050194092,0.000013969024,0.0014093608],"genre_scores_gemma":[0.994457,0.0012899358,0.000727385,0.00012142696,0.00011105344,0.00003739646,0.00030364856,0.00002908562,0.0029230728],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998744,0.00008313264,0.00026627633,0.00047548497,0.00015617062,0.00027493044],"domain_scores_gemma":[0.999064,0.000008245376,0.00013600037,0.00037606107,0.00011647807,0.00029920138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014585293,0.00021707361,0.00017650155,0.00003377684,0.000074839474,0.00002538712,0.0001585454,0.00015924181,0.00006224202],"category_scores_gemma":[0.00005276727,0.00019679524,0.00006593324,0.00011975893,0.00018103793,0.000011803958,0.000064982625,0.00008753597,0.000011621041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008515465,0.00011149154,0.011796521,0.00016666848,0.000010842485,0.000003843376,0.00006572589,0.000006232225,0.9836127,0.00000851635,0.0028370873,0.00052879186],"study_design_scores_gemma":[0.0015113667,0.00046473191,0.002581342,0.000030179695,0.000028714721,0.0000012965016,0.000028227194,0.00021559051,0.99133956,0.00024325043,0.003308926,0.00024681137],"about_ca_topic_score_codex":0.000013750732,"about_ca_topic_score_gemma":7.225183e-7,"teacher_disagreement_score":0.00921518,"about_ca_system_score_codex":0.00003900171,"about_ca_system_score_gemma":0.00045563423,"threshold_uncertainty_score":0.8025077},"labels":[],"label_agreement":null},{"id":"W2894744183","doi":"10.1038/s41419-018-1069-9","title":"Dianhydrogalactitol induces replication-dependent DNA damage in tumor cells preferentially resolved by homologous recombination","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Prevention of Organ Failure; Delmar (Canada); University of British Columbia","funders":"Mitacs","keywords":"Homologous recombination; DNA damage; DNA repair; Guanine; DNA; DNA replication; Biology; Cancer research; Cytotoxicity; Cell cycle; Chemistry; Cell biology; Molecular biology; Cell; In vitro; Biochemistry; Gene","score_opus":0.008077137896643959,"score_gpt":0.22954690268280603,"score_spread":0.22146976478616207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2894744183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964265,0.00028792836,0.00020179732,0.00005497355,0.0001545833,0.00029718303,0.00005753648,0.000021794975,0.0024977066],"genre_scores_gemma":[0.99745953,0.000080655744,0.0001666349,0.00021599098,0.00009398972,0.000060599956,0.00032094747,0.000018920095,0.00158271],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989239,0.00007035135,0.00016846838,0.00053106976,0.00010333671,0.00020287567],"domain_scores_gemma":[0.99907374,0.00000842203,0.00007802662,0.00050525734,0.000054660046,0.00027988356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013700654,0.0001363298,0.000095944466,0.000047174413,0.00007179766,0.000040413648,0.0001481198,0.000084576786,0.000047650647],"category_scores_gemma":[0.00008828425,0.0001398263,0.000036515634,0.000051538427,0.000048540718,0.000010009871,0.000096113254,0.00006005543,0.000022667999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014967476,0.00024339498,0.002054419,0.000025513134,0.0000065990944,0.0000097589245,0.000030104324,8.564992e-7,0.9943225,0.00005191661,0.0024468808,0.0006584166],"study_design_scores_gemma":[0.0007525797,0.00022464931,0.00519858,0.000009406945,0.000023574208,0.0000012233579,0.000030161966,0.00006936116,0.98997504,0.0007272157,0.0028020658,0.00018616232],"about_ca_topic_score_codex":0.000030174058,"about_ca_topic_score_gemma":0.00002973956,"teacher_disagreement_score":0.004347446,"about_ca_system_score_codex":0.000017513767,"about_ca_system_score_gemma":0.00009734252,"threshold_uncertainty_score":0.5701951},"labels":[],"label_agreement":null},{"id":"W2896444571","doi":"10.1038/s41419-018-1122-8","title":"BTK: a two-faced effector in cancer and tumour suppression","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Bruton's tyrosine kinase; Biology; Suppressor; Tyrosine kinase; Effector; Context (archaeology); Cancer research; Cancer; Gene; Cancer cell; Phenotype; Organism; Signal transduction; Genetics; Cell biology","score_opus":0.017650878871540775,"score_gpt":0.3236118944351496,"score_spread":0.30596101556360883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896444571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931092,0.0045393556,0.000007016578,0.00022104506,0.000066006556,0.000377556,0.00001817155,0.000021073887,0.0016405621],"genre_scores_gemma":[0.9977915,0.00025384952,0.000043280004,0.00031322558,0.00020115077,0.000045273242,0.000012679908,0.000014678528,0.0013243414],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991329,0.000032815482,0.00010139231,0.00027803276,0.0001729813,0.00028190395],"domain_scores_gemma":[0.9988658,0.00006698581,0.000017469232,0.0001760152,0.000036433357,0.0008373344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000092920156,0.00010974163,0.00015916803,0.000071992785,0.000052527495,0.000021344269,0.000039166443,0.0000370083,0.00020187946],"category_scores_gemma":[0.0001413039,0.00008252084,0.000024039819,0.00008440822,0.00011018328,0.00004678905,0.00008256015,0.000086111664,0.000035213652],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014199378,0.001089527,0.79295844,0.0048182104,0.00006927327,0.0035748128,0.0016285405,0.000011563038,0.14104173,0.00020845268,0.02178382,0.018616255],"study_design_scores_gemma":[0.12088301,0.0009883229,0.7425921,0.0015001363,0.0004169385,0.00007644645,0.00013352172,0.075657785,0.049059987,0.0006608462,0.007343196,0.00068771036],"about_ca_topic_score_codex":0.0006899283,"about_ca_topic_score_gemma":0.000043275493,"teacher_disagreement_score":0.106683634,"about_ca_system_score_codex":0.0006745524,"about_ca_system_score_gemma":0.0017704878,"threshold_uncertainty_score":0.3365102},"labels":[],"label_agreement":null},{"id":"W2897914092","doi":"10.1038/s41419-018-1120-x","title":"The Zen of XEN: insight into differentiation, metabolism and genomic integrity","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Child and Family Research Institute; Ontario Institute for Regenerative Medicine; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Epiblast; Endoderm; Homeobox protein NANOG; Biology; Embryonic stem cell; Cell biology; Blastocyst; Inner cell mass; Trophoblast; Rex1; Stem cell; Nanog Homeobox Protein; Embryo; SOX2; Induced pluripotent stem cell; Genetics; Embryogenesis; Placenta; Gastrulation; Gene","score_opus":0.009759654714220222,"score_gpt":0.24392519098094084,"score_spread":0.23416553626672063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897914092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868521,0.011567549,0.00023913787,0.00013894941,0.00005446495,0.00012288298,0.00001525565,0.0000030796928,0.0010066],"genre_scores_gemma":[0.9969705,0.0020672863,0.00006945926,0.00007830298,0.000117503136,0.0000077246295,0.00003458486,0.0000075026287,0.00064718677],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99942,0.000055875378,0.00010638575,0.00019861548,0.00008401947,0.00013513467],"domain_scores_gemma":[0.9993986,0.000014344095,0.000036369423,0.00022637157,0.000082478815,0.00024185838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009515342,0.000082835104,0.000076582066,0.000020852782,0.00015123995,0.000030961062,0.00010973284,0.000045328343,0.000009143319],"category_scores_gemma":[0.00007672824,0.000055738914,0.000032037493,0.000028838876,0.00019323402,0.0000031960167,0.00018130762,0.000049895963,0.00000440078],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005105625,0.000112258356,0.055194095,0.00012975952,0.000053677195,0.0000029641437,0.00023575785,5.078582e-7,0.93689835,0.00069086754,0.0014526587,0.0047185402],"study_design_scores_gemma":[0.0013887954,0.00020110505,0.6115235,0.000013655577,0.000112861075,0.000002140891,0.00008624183,0.00055074674,0.30084953,0.0032516462,0.08173805,0.0002817345],"about_ca_topic_score_codex":0.000026047339,"about_ca_topic_score_gemma":0.000014492312,"teacher_disagreement_score":0.63604885,"about_ca_system_score_codex":0.0000035073685,"about_ca_system_score_gemma":0.00007276363,"threshold_uncertainty_score":0.22729668},"labels":[],"label_agreement":null},{"id":"W2899027440","doi":"10.1038/s41419-018-1142-4","title":"YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; University of Pennsylvania; Sarcoma Foundation of America; V Foundation for Cancer Research; National Institutes of Health; American Cancer Society","keywords":"Biology; YAP1; Cell biology; Skeletal muscle; Autophagy; Cancer research; Hippo signaling pathway; Cellular differentiation; Myocyte; Carcinogenesis; Signal transduction; Transcription factor; Endocrinology; Cancer; Apoptosis; Genetics","score_opus":0.00907530129535537,"score_gpt":0.26023942736300254,"score_spread":0.25116412606764715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899027440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98821753,0.0096769165,0.000009752686,0.000248511,0.0000810189,0.001045459,0.000030037892,0.00007004384,0.0006207333],"genre_scores_gemma":[0.9968605,0.0005721753,0.000045158962,0.0011904928,0.00016395355,0.00011652443,0.000024200732,0.000026682104,0.0010002845],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984676,0.00014491708,0.00023057924,0.00051917613,0.00028824282,0.0003494431],"domain_scores_gemma":[0.9984354,0.00018031367,0.000068500696,0.0002844626,0.00004148492,0.0009898626],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017675382,0.00027144773,0.00032224468,0.00019581422,0.00012683544,0.000049942195,0.00006452375,0.00011067584,0.000072566036],"category_scores_gemma":[0.00022351538,0.00022052797,0.00004339074,0.00011159635,0.00016733509,0.000089579196,0.00006576997,0.00016294554,0.000029688994],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06656854,0.00448033,0.39735734,0.0040573934,0.00032438088,0.010838421,0.002765533,0.0000010384919,0.43455008,0.0026132055,0.00080452755,0.0756392],"study_design_scores_gemma":[0.010299046,0.002020486,0.74393314,0.0005010095,0.00016849618,0.000020268639,0.00010283674,0.00029373242,0.23841558,0.0032116976,0.0006226184,0.0004110579],"about_ca_topic_score_codex":0.00004150931,"about_ca_topic_score_gemma":0.000010224702,"teacher_disagreement_score":0.34657583,"about_ca_system_score_codex":0.000033538367,"about_ca_system_score_gemma":0.00019106711,"threshold_uncertainty_score":0.899287},"labels":[],"label_agreement":null},{"id":"W2901948004","doi":"10.1038/s41419-018-1206-5","title":"BAP1 regulates different mechanisms of cell death","year":2018,"lang":"en","type":"letter","venue":"Cell Death and Disease","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research; National Cancer Institute; U.S. Department of Health and Human Services; University of Hawaiʻi Foundation; U.S. Department of Defense","keywords":"Cell biology; Programmed cell death; Apoptosis; Biology; Genetics","score_opus":0.011503192885754444,"score_gpt":0.2163622923487971,"score_spread":0.20485909946304265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901948004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95751166,0.004508,0.00019951157,0.026165107,0.0004173018,0.001071708,0.0018176846,0.00009844472,0.00821055],"genre_scores_gemma":[0.83848894,0.00036365777,0.0004154489,0.13583715,0.001479619,0.000050754934,0.0039859316,0.000084315514,0.019294195],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9984586,0.000034283305,0.00027382345,0.0004854634,0.0004399267,0.00030785112],"domain_scores_gemma":[0.9986662,0.000053389347,0.00013643308,0.0004235289,0.000033321052,0.00068711676],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000026541229,0.0003787092,0.00043697993,0.000097486925,0.00007412156,0.000018285657,0.00010387129,0.0002392959,0.00094604556],"category_scores_gemma":[0.000018347193,0.00028687128,0.0002461902,0.00003467464,0.00010719128,0.000038860668,0.000100424215,0.00023755376,0.00008631304],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012550928,0.0014245387,0.14760707,0.006616827,0.00014173084,0.0010412706,0.000037371236,0.0000017336059,0.0050368034,0.00018429878,0.83643097,0.00022231732],"study_design_scores_gemma":[0.0044644945,0.0013881427,0.8440105,0.0009458383,0.005214631,0.000017401433,0.000035023353,0.00033983384,0.022434669,0.025249125,0.0945312,0.001369176],"about_ca_topic_score_codex":0.000014996308,"about_ca_topic_score_gemma":1.8988099e-7,"teacher_disagreement_score":0.7418997,"about_ca_system_score_codex":0.000048446214,"about_ca_system_score_gemma":0.000094921306,"threshold_uncertainty_score":0.9999672},"labels":[],"label_agreement":null},{"id":"W2908924740","doi":"10.1038/s41419-018-1274-6","title":"Erythropoietin inhibits chemotherapy-induced cell death and promotes a senescence-like state in leukemia cells","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"York University","keywords":"Daunorubicin; Erythropoietin; Erythropoietin receptor; Cancer research; Erythropoiesis; Mdm2; Downregulation and upregulation; DNA damage; Senescence; Apoptosis; Doxorubicin; Myeloid leukemia; Biology; Leukemia; Immunology; Cell biology; Medicine; Chemotherapy; Internal medicine; Anemia; Endocrinology; Gene","score_opus":0.013779279698426749,"score_gpt":0.25378885000207196,"score_spread":0.24000957030364523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2908924740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993895,0.0020241428,0.0000440095,0.00029508036,0.00015347135,0.001089299,0.000042451848,0.00007096585,0.0023855912],"genre_scores_gemma":[0.9933067,0.0013497384,0.00033619828,0.0020083063,0.00008471281,0.000048530135,0.000031941214,0.00005483551,0.002779058],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982397,0.00006323676,0.00032448437,0.00063749857,0.00027267137,0.00046240125],"domain_scores_gemma":[0.998535,0.0000586504,0.00010821735,0.0003826091,0.00006365501,0.0008518664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016124407,0.00032691186,0.00039222403,0.00014836196,0.00006561506,0.00005448738,0.000070585615,0.00010649887,0.00023505953],"category_scores_gemma":[0.00001189246,0.00029576386,0.00007536179,0.00017739407,0.00007204277,0.00013524953,0.00004713728,0.00023770137,0.00008027535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024910541,0.00069125876,0.27747443,0.001655109,0.000026953869,0.00027555137,0.001829155,0.000016263728,0.7111053,0.000031657855,0.0012818014,0.0031214855],"study_design_scores_gemma":[0.026730536,0.0009843839,0.12836155,0.0009449766,0.00014570782,0.000032177795,0.00038409914,0.0019436798,0.8336186,0.0019964029,0.0037255075,0.0011323858],"about_ca_topic_score_codex":0.00013030418,"about_ca_topic_score_gemma":0.0000056402996,"teacher_disagreement_score":0.14911288,"about_ca_system_score_codex":0.00016370349,"about_ca_system_score_gemma":0.00052643724,"threshold_uncertainty_score":0.99994946},"labels":[],"label_agreement":null},{"id":"W2910456696","doi":"10.1038/s41419-018-1276-4","title":"HACE1 is a potential tumor suppressor in osteosarcoma","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; Spinal Cord Injury BC; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Osteosarcoma; Cancer research; Ectopic expression; Biology; Tumor suppressor gene; Cell culture; Molecular biology; Chemistry; Carcinogenesis; Cancer; Genetics","score_opus":0.0033248765739017265,"score_gpt":0.20275185001063117,"score_spread":0.19942697343672944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2910456696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99601775,0.002708552,0.00005535527,0.00013131324,0.0001064642,0.00020102462,0.000037681464,0.000005863268,0.0007359821],"genre_scores_gemma":[0.99778557,0.0000498486,0.000043464082,0.00028505977,0.000085981774,0.000011018779,0.00011405185,0.00001190762,0.0016131074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999406,0.000018888426,0.00009146459,0.00026240564,0.00006775134,0.00015351686],"domain_scores_gemma":[0.9995555,0.0000022925892,0.000026744869,0.00020760261,0.00001746909,0.00019036967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000028720622,0.000090105146,0.00007204993,0.000030447882,0.000020948597,0.000017880919,0.000053827807,0.000051544423,0.00009003899],"category_scores_gemma":[0.000009651274,0.00009088959,0.00004733143,0.000035560748,0.000017459635,0.0000035234025,0.00005337242,0.00003675902,0.000029618672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091439346,0.00014115994,0.07076439,0.0001281276,0.00001424919,0.00003457007,0.0000506606,0.00047346094,0.9224518,0.00003422986,0.0038036797,0.0011892514],"study_design_scores_gemma":[0.009248513,0.0005225713,0.38722217,0.000078757286,0.00014948122,0.000027434508,0.00010847157,0.0083162375,0.54004866,0.0009809585,0.052280396,0.001016378],"about_ca_topic_score_codex":0.000017291422,"about_ca_topic_score_gemma":0.0000044898698,"teacher_disagreement_score":0.3824032,"about_ca_system_score_codex":0.000008087212,"about_ca_system_score_gemma":0.000077367564,"threshold_uncertainty_score":0.370637},"labels":[],"label_agreement":null},{"id":"W2911289911","doi":"10.1038/s41419-019-1354-2","title":"DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Ottawa","funders":"Krembil Foundation; Canadian Institutes of Health Research; EU Joint Programme – Neurodegenerative Disease Research; Fondation Brain Canada","keywords":"Unfolded protein response; ATF4; Endoplasmic reticulum; Biology; Downregulation and upregulation; Programmed cell death; XBP1; Wild type; Cell biology; Integrated stress response; Transcription factor; Mutant; Genetics; Cancer research; Gene; Apoptosis; Translation (biology); RNA splicing; Messenger RNA; RNA","score_opus":0.0045097540227281695,"score_gpt":0.20698956991002646,"score_spread":0.2024798158872983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911289911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99480927,0.003971333,0.00012795003,0.0000630901,0.000046107318,0.00048938894,0.00006822875,0.000008613954,0.0004160313],"genre_scores_gemma":[0.9986227,0.000079476515,0.00010960707,0.00008150939,0.000036294718,0.000029428124,0.00009532203,0.000018202605,0.0009274264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905545,0.000096959644,0.00017194774,0.00034114433,0.00013471139,0.00019977495],"domain_scores_gemma":[0.9991562,0.000031444622,0.00008177916,0.0003766751,0.000037646932,0.00031629644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010857447,0.00017256904,0.00014091734,0.000027903443,0.00008655554,0.000035282446,0.0000998002,0.000074414456,0.000015953065],"category_scores_gemma":[0.000055626035,0.00012699065,0.00010643688,0.000037742528,0.000050191426,0.00000994195,0.000103261315,0.00004599704,0.0000031442953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022128802,0.0001794693,0.2562444,0.00031377145,0.00003423406,0.000018450784,0.00007801941,0.0003443192,0.73992354,0.00010213312,0.00009108323,0.00045773352],"study_design_scores_gemma":[0.0044503813,0.0004303194,0.43557963,0.00015221773,0.00031956946,0.0000029777532,0.00024629355,0.006815398,0.5490172,0.0016941803,0.00066264335,0.00062917446],"about_ca_topic_score_codex":0.000023408304,"about_ca_topic_score_gemma":0.0000013058025,"teacher_disagreement_score":0.19090632,"about_ca_system_score_codex":0.000005000639,"about_ca_system_score_gemma":0.00007859953,"threshold_uncertainty_score":0.51785284},"labels":[],"label_agreement":null},{"id":"W2911578183","doi":"10.1038/s41419-019-1359-x","title":"Hypoxia-induced 26S proteasome dysfunction increases immunogenicity of mesenchymal stem cells","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Yarmouk University; Research Manitoba","keywords":"Mesenchymal stem cell; Proteasome; Immune system; MHC class I; Immunogenicity; Transplantation; Cell biology; Biology; Immunology; Major histocompatibility complex; Cancer research; Chemistry; Medicine; Internal medicine","score_opus":0.01134622061902069,"score_gpt":0.21000311818772105,"score_spread":0.19865689756870036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911578183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99525493,0.002138135,0.000050362745,0.000012354565,0.0001121975,0.00059822935,0.00009883939,0.000015899192,0.0017190344],"genre_scores_gemma":[0.9981763,0.00012841288,0.00007129006,0.00011531655,0.000095736345,0.00004101802,0.0000732527,0.000019190118,0.0012795179],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989855,0.00008182658,0.00019355676,0.00036780536,0.00014079337,0.00023047849],"domain_scores_gemma":[0.99907225,0.000013866639,0.00010305067,0.00038625798,0.000069606205,0.0003549425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012579854,0.00018010203,0.0001732902,0.000038137387,0.00006086846,0.000020324009,0.000120624616,0.000108435706,0.00007727971],"category_scores_gemma":[0.00002548633,0.00016465013,0.000116982024,0.00005540118,0.000036281166,0.000008379106,0.00011616687,0.00006991163,0.000038217902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00061242224,0.00017842805,0.013524544,0.00020650007,0.000022606466,0.0000053672093,0.000015708712,0.0000060976186,0.98424494,0.00007052026,0.000111628135,0.0010012459],"study_design_scores_gemma":[0.0011767572,0.00041959426,0.012236644,0.000026362237,0.00005370762,0.0000040836035,0.00005685152,0.0000777499,0.9841708,0.000119884084,0.0014176313,0.00023995129],"about_ca_topic_score_codex":0.00005292986,"about_ca_topic_score_gemma":0.0000011948504,"teacher_disagreement_score":0.0029213175,"about_ca_system_score_codex":0.000008336286,"about_ca_system_score_gemma":0.00016631991,"threshold_uncertainty_score":0.67142373},"labels":[],"label_agreement":null},{"id":"W2911610960","doi":"10.1038/s41419-019-1363-1","title":"Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Sunnybrook Hospital","funders":"National Natural Science Foundation of China; National Science Foundation","keywords":"Transcription factor; Biology; Cell growth; Proto-Oncogene Proteins c-myc; Downregulation and upregulation; Leukemia; Haematopoiesis; Apoptosis; Cell biology; Cancer research; Gene; Molecular biology; Chemistry; Stem cell; Biochemistry; Genetics","score_opus":0.010442834482292863,"score_gpt":0.22084189813879745,"score_spread":0.2103990636565046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911610960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979084,0.0003503012,0.00035279474,0.000031915824,0.00005997695,0.0002729038,0.00011897761,0.000007392153,0.00089732406],"genre_scores_gemma":[0.99825794,0.000037684968,0.00006941718,0.00012949237,0.000036729187,0.000022405693,0.00016795764,0.000014866302,0.0012635305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936694,0.000026376532,0.00011174583,0.0002692732,0.000087728054,0.00013794837],"domain_scores_gemma":[0.99940103,0.0000069902508,0.00005786993,0.0002795618,0.000037665137,0.00021688415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000620123,0.00010975268,0.00010224302,0.000041354047,0.000039525516,0.000034332625,0.000114755254,0.000041182513,0.000027099833],"category_scores_gemma":[0.000011578202,0.00009312817,0.000038990365,0.00004035124,0.000024735073,0.000006144542,0.000079904596,0.0000252305,0.000021425945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003867519,0.000047515445,0.06453637,0.00015683798,0.000012165261,0.0000022612016,0.00005604225,0.000009647462,0.9342693,0.00002366965,0.00023263207,0.0002667775],"study_design_scores_gemma":[0.00047747223,0.00019065916,0.019925322,0.000032986565,0.000031850268,0.000001981672,0.000076711876,0.000053313637,0.9774614,0.000020116713,0.0015733457,0.00015483174],"about_ca_topic_score_codex":0.0000045582583,"about_ca_topic_score_gemma":0.0000015199134,"teacher_disagreement_score":0.044611048,"about_ca_system_score_codex":0.000006390557,"about_ca_system_score_gemma":0.000048241753,"threshold_uncertainty_score":0.37976563},"labels":[],"label_agreement":null},{"id":"W2912686306","doi":"10.1038/s41419-018-1199-0","title":"High cholesterol triggers white matter alterations and cognitive deficits in a mouse model of cerebrovascular disease: benefits of simvastatin","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; University of California, San Francisco; Alzheimer Society; McGill University","keywords":"Simvastatin; White matter; Cholesterol; Medicine; Disease; Neuroscience; Pharmacology; Internal medicine; Cardiology; Endocrinology; Biology; Magnetic resonance imaging","score_opus":0.01805768728042718,"score_gpt":0.2204710845895834,"score_spread":0.20241339730915622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912686306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99787027,0.000057103312,0.00081285083,0.000109769295,0.000030994386,0.00051138224,0.0004946684,0.000014840398,0.00009814295],"genre_scores_gemma":[0.9981558,0.0000864724,0.000098634315,0.00085531763,0.000006451147,0.000025863601,0.000023764711,0.000017809822,0.00072993495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886787,0.000097801705,0.00029004933,0.00038581208,0.00020764339,0.00015084485],"domain_scores_gemma":[0.9992455,0.0000827999,0.00011560237,0.0001895941,0.00004731317,0.00031919364],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053468146,0.00014734281,0.00018390133,0.00015185738,0.000046825822,0.000038353126,0.000064386935,0.000024119547,0.000059707836],"category_scores_gemma":[0.00008752417,0.00014276787,0.000049108687,0.00010485631,0.000044247794,0.00021784248,0.000043494183,0.000063294916,0.000014514943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007385083,0.00062936073,0.122518614,0.0008712868,0.0000071108834,0.000010045606,0.00067793066,0.071418874,0.79391634,0.0087839365,0.00004615841,0.00038181036],"study_design_scores_gemma":[0.004562026,0.000118133874,0.083382554,0.00011383379,0.00010431736,0.0000014456633,0.000049570113,0.10884692,0.80149907,0.00095123687,0.0000037396574,0.00036712395],"about_ca_topic_score_codex":0.0000027644528,"about_ca_topic_score_gemma":0.0000016571464,"teacher_disagreement_score":0.039136056,"about_ca_system_score_codex":0.000004319776,"about_ca_system_score_gemma":0.00006158745,"threshold_uncertainty_score":0.58219045},"labels":[],"label_agreement":null},{"id":"W2912778251","doi":"10.1038/s41419-018-1294-2","title":"Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Seventh Framework Programme; Université de Montréal; Université Paris Descartes; Vrije Universiteit Amsterdam; European Commission; Amsterdam Neuroscience; Amsterdam University Medical Centers","keywords":"Downregulation and upregulation; SNAI1; Inflammation; Mesenchymal stem cell; Biology; Endothelial stem cell; Multiple sclerosis; Cell biology; Endothelial dysfunction; Blood–brain barrier; Neuroscience; Neuroprotection; Pathophysiology; Epithelial–mesenchymal transition; Immunology; Central nervous system; Endocrinology; In vitro","score_opus":0.018045441562526,"score_gpt":0.2077269259180602,"score_spread":0.1896814843555342,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912778251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99774736,0.000061645085,0.00017688582,0.0003850525,0.00043105157,0.000585883,0.00016856495,0.00007390516,0.00036966268],"genre_scores_gemma":[0.99847144,0.000047110534,0.0000496773,0.00081791054,0.00023274789,0.000054231223,0.000010281506,0.000017123652,0.00029948124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987345,0.00009739552,0.00018572639,0.00054749165,0.00015902381,0.00027585967],"domain_scores_gemma":[0.99919033,0.00015167588,0.00006244062,0.00017735873,0.000032565593,0.00038565812],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005486642,0.00020602392,0.00018725549,0.00010509975,0.00030968105,0.00006482204,0.000059330287,0.00006437578,0.000047888865],"category_scores_gemma":[0.00020256302,0.00018252645,0.00005979945,0.00011275613,0.000047568086,0.0002199856,0.000053057942,0.00010350481,0.000049579143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006790436,0.000032366643,0.0038107485,0.0001147177,0.0000028869833,0.000007579643,0.0008266457,0.000030241665,0.99308413,0.00005702368,0.000031519485,0.0013231203],"study_design_scores_gemma":[0.0036722678,0.0003460072,0.09578009,0.00003025292,0.00005709645,0.00000459333,0.00024772293,0.0007577406,0.8974697,0.0008659821,0.0003654614,0.0004031021],"about_ca_topic_score_codex":0.000020753241,"about_ca_topic_score_gemma":0.0000032987452,"teacher_disagreement_score":0.09561442,"about_ca_system_score_codex":0.000017059807,"about_ca_system_score_gemma":0.000040645577,"threshold_uncertainty_score":0.7443213},"labels":[],"label_agreement":null},{"id":"W2913508461","doi":"10.1038/s41419-019-1316-8","title":"Ser46 phosphorylation of p53 is an essential event in prolyl-isomerase Pin1-mediated p53-independent apoptosis in response to heat stress","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"PIN1; Prolyl isomerase; Phosphorylation; Cell biology; Biology; Peptidylprolyl isomerase; Apoptosis; Mitochondrion; Signal transduction; Reactive oxygen species; Context (archaeology); Transcription factor; Mediator; Cancer research; Biochemistry; Isomerase; Gene","score_opus":0.006482185021590343,"score_gpt":0.24010880262614107,"score_spread":0.23362661760455072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913508461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99776524,0.000998146,0.000053682026,0.000092366296,0.00009615527,0.0006462012,0.00030438098,0.000009221902,0.000034607612],"genre_scores_gemma":[0.9989824,0.00005756922,0.0000494494,0.00032662245,0.000038066577,0.00006661698,0.00033189222,0.000024022544,0.0001233502],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850965,0.00015784027,0.00030445663,0.0005335255,0.00021925836,0.0002752809],"domain_scores_gemma":[0.99883705,0.000024846875,0.0000578502,0.00044189376,0.000059855116,0.0005784969],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023987918,0.00019163192,0.00018481429,0.00012574835,0.000024860194,0.000021350937,0.00015332157,0.00011391019,0.00008002518],"category_scores_gemma":[0.00014275691,0.00020147923,0.000069164766,0.000153219,0.000027250167,0.0000121762605,0.00010427689,0.0000754486,0.000013592173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0073567783,0.0007439265,0.30578876,0.00013229047,0.000009868373,0.000019474728,0.00024659507,0.0015306706,0.68392515,0.000003151695,0.000077932054,0.00016540478],"study_design_scores_gemma":[0.0032129392,0.00044268402,0.20072523,0.00011016843,0.000037036905,4.9261394e-7,0.00019727883,0.0013054083,0.79343075,0.000055059452,0.00012910886,0.00035385104],"about_ca_topic_score_codex":0.00010679211,"about_ca_topic_score_gemma":0.000023870221,"teacher_disagreement_score":0.10950558,"about_ca_system_score_codex":0.00003269814,"about_ca_system_score_gemma":0.0002669491,"threshold_uncertainty_score":0.8216084},"labels":[],"label_agreement":null},{"id":"W2913586357","doi":"10.1038/s41419-019-1350-6","title":"MKK3 modulates JNK-dependent cell migration and invasion","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Natural Science Foundation of China","keywords":"Cell biology; Cell migration; Cell; Chemistry; Biology; Biochemistry","score_opus":0.006426854840862928,"score_gpt":0.19003002857505338,"score_spread":0.18360317373419047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913586357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993639,0.0032781612,0.00009519133,0.000043043925,0.00007980525,0.00016479215,0.000022680286,0.000007928648,0.0026694045],"genre_scores_gemma":[0.99593306,0.00064296054,0.00008047983,0.00021243864,0.000067336165,0.0000074104123,0.0001707105,0.000009792402,0.0028758117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994351,0.000019161187,0.000079786274,0.00027725482,0.00006221515,0.00012643384],"domain_scores_gemma":[0.9994776,0.0000048848174,0.000028800709,0.00018501145,0.000018809698,0.00028489463],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000041123887,0.00010316141,0.000071266186,0.000019288664,0.000045958353,0.000028069602,0.00004200993,0.0000620308,0.000024797737],"category_scores_gemma":[0.0000114550385,0.00009008924,0.000029385588,0.00001405763,0.000014712237,0.000004794371,0.00006453615,0.00002986011,0.00002590841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012337482,0.00007289683,0.1503723,0.00012787423,0.000004059505,0.000009063581,0.000034084664,0.00001534882,0.8478728,0.00007321959,0.00061799056,0.00067702064],"study_design_scores_gemma":[0.0029231217,0.00066879136,0.14530076,0.000031954158,0.0001023799,0.00000915371,0.00014470107,0.0016838278,0.82501614,0.0012089688,0.02225999,0.0006502166],"about_ca_topic_score_codex":0.000018445888,"about_ca_topic_score_gemma":0.0000069369084,"teacher_disagreement_score":0.022856643,"about_ca_system_score_codex":0.0000026447283,"about_ca_system_score_gemma":0.00003860435,"threshold_uncertainty_score":0.36737326},"labels":[],"label_agreement":null},{"id":"W2913806057","doi":"10.1038/s41419-018-1283-5","title":"Eukaryotic initiation factor 5B (eIF5B) provides a critical cell survival switch to glioblastoma cells via regulation of apoptosis","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; Ministero dello Sviluppo Economico","keywords":"Internal ribosome entry site; XIAP; Eukaryotic initiation factor; Cell biology; Biology; Translation (biology); Apoptosis; Eukaryotic translation; EIF4E; Eukaryotic translation initiation factor 4 gamma; Caspase; Programmed cell death; Messenger RNA; Biochemistry; Gene","score_opus":0.008125115964295672,"score_gpt":0.23514431675006572,"score_spread":0.22701920078577006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913806057","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956951,0.00022968385,0.0023151273,0.00011114288,0.00016761632,0.00040883134,0.00009079681,0.000016623835,0.00096507417],"genre_scores_gemma":[0.99843997,0.00001805565,0.00022473955,0.00026666024,0.00009046631,0.000018085277,0.000113539565,0.000022112981,0.0008063739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988904,0.000066364984,0.00023626571,0.0003897707,0.000200185,0.00021701722],"domain_scores_gemma":[0.9987665,0.0000334953,0.00007040371,0.00031713778,0.00013738693,0.0006750967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000060556995,0.00017485861,0.0001574646,0.00007672885,0.000053543736,0.000036921585,0.000088489454,0.00009188881,0.00014317826],"category_scores_gemma":[0.00009944263,0.00017130519,0.00009924347,0.00009307137,0.000038291757,0.000017405371,0.00006854168,0.00003695863,0.00005033723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001055237,0.0003147153,0.084666915,0.00043336878,0.000009278871,0.0000017264007,0.00005220197,0.0002540507,0.91213894,0.00016521367,0.00046166213,0.00044667628],"study_design_scores_gemma":[0.0016279224,0.0005875011,0.3519487,0.000036792982,0.00011018893,6.674314e-7,0.0000667435,0.0024804282,0.6414553,0.00048469575,0.0007439861,0.00045705677],"about_ca_topic_score_codex":0.000007977873,"about_ca_topic_score_gemma":0.0000014953704,"teacher_disagreement_score":0.27068365,"about_ca_system_score_codex":0.000012286276,"about_ca_system_score_gemma":0.00014068992,"threshold_uncertainty_score":0.69856226},"labels":[],"label_agreement":null},{"id":"W2914436528","doi":"10.1038/s41419-019-1311-0","title":"SVIP alleviates CCl4-induced liver fibrosis via activating autophagy and protecting hepatocytes","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Science Foundation of Anhui Province; Natural Science Foundation of Liaoning Province; National Natural Science Foundation of China","keywords":"Autophagy; TFEB; Fibrosis; Cell biology; In vivo; Hepatic fibrosis; Hepatic stellate cell; Programmed cell death; Transcription factor; Cancer research; Intracellular; Biology; Chemistry; Medicine; Biochemistry; Pathology; Endocrinology; Apoptosis","score_opus":0.01463967132921521,"score_gpt":0.24091121547378638,"score_spread":0.22627154414457118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914436528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913095,0.0062696734,0.000069730646,0.000088849134,0.0000551634,0.0008147799,0.000008781118,0.00010857336,0.0012749224],"genre_scores_gemma":[0.9977703,0.00024461883,0.00036062527,0.00060705334,0.00012462221,0.000054755947,0.000015297785,0.000033183667,0.0007895605],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989001,0.000049369304,0.00017729471,0.00040547524,0.00016802407,0.00029972917],"domain_scores_gemma":[0.9987626,0.00011523492,0.000082103346,0.00025891056,0.0000437278,0.00073739025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009741876,0.00022293239,0.00026738775,0.00006582477,0.0001833669,0.00005081465,0.00005083926,0.000077221164,0.00040490896],"category_scores_gemma":[0.000095334355,0.00018682546,0.00008624926,0.00007308561,0.000031550375,0.00015610464,0.000062647654,0.0001720231,0.00007042289],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035442766,0.0010675011,0.4902809,0.0041077617,0.00029277545,0.0006435824,0.0019219064,0.000005665321,0.40783814,0.00035440375,0.00019065026,0.08975246],"study_design_scores_gemma":[0.007355936,0.00085341965,0.78214186,0.0006006261,0.00040505867,0.000036932248,0.0003862557,0.016543185,0.18847178,0.0013265017,0.0010709537,0.0008074825],"about_ca_topic_score_codex":0.000052100964,"about_ca_topic_score_gemma":3.0425653e-7,"teacher_disagreement_score":0.29186097,"about_ca_system_score_codex":0.000023651257,"about_ca_system_score_gemma":0.00010932386,"threshold_uncertainty_score":0.76185215},"labels":[],"label_agreement":null},{"id":"W2922394097","doi":"10.1038/s41419-019-1320-z","title":"LAMB3 mediates apoptotic, proliferative, invasive, and metastatic behaviors in pancreatic cancer by regulating the PI3K/Akt signaling pathway","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":186,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Department of Education of Guizhou Province; Guizhou Medical University; Guizhou Science and Technology Department","keywords":"PI3K/AKT/mTOR pathway; Cancer research; Protein kinase B; Metastasis; Biology; Pancreatic cancer; Signal transduction; Cell growth; Cell cycle; Adenocarcinoma; Cancer; Apoptosis; Cell biology","score_opus":0.018335195860019908,"score_gpt":0.28055288667395506,"score_spread":0.26221769081393514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922394097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913775,0.006724354,0.000007842841,0.0003977547,0.000023514423,0.0011190049,0.00003196149,0.000017680202,0.00030041134],"genre_scores_gemma":[0.9973064,0.00040352892,0.00015527569,0.00040762548,0.000027194792,0.00014895147,0.000055760764,0.000028342769,0.001466932],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985226,0.0001488154,0.00025414192,0.00037823626,0.00035155422,0.0003446614],"domain_scores_gemma":[0.9986392,0.0003884343,0.000068303074,0.00023827332,0.00007309923,0.00059268915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002254587,0.00019448405,0.00030291206,0.00009743393,0.00009810636,0.00006193858,0.000074339165,0.00003769858,0.00023925773],"category_scores_gemma":[0.0003359485,0.00012891511,0.000046492198,0.00017137668,0.000098791934,0.00008111246,0.000085520376,0.00020979997,0.000014532101],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035665234,0.000185662,0.79230756,0.0007225166,0.00002400258,0.00010737163,0.000639283,0.000028200697,0.20434651,0.000046728157,0.00018292811,0.001052595],"study_design_scores_gemma":[0.017816009,0.0012827195,0.48816994,0.0021145765,0.0015086686,0.000034732137,0.004882802,0.0149435755,0.46564117,0.0014663906,0.0007061376,0.0014332966],"about_ca_topic_score_codex":0.00015106311,"about_ca_topic_score_gemma":0.000020934805,"teacher_disagreement_score":0.30413762,"about_ca_system_score_codex":0.000041415118,"about_ca_system_score_gemma":0.00031509242,"threshold_uncertainty_score":0.52570057},"labels":[],"label_agreement":null},{"id":"W2925670234","doi":"10.1038/s41419-019-1518-0","title":"Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds Wetenschappelijk Onderzoek; Universiteit Maastricht; European Commission; European Federation of Pharmaceutical Industries and Associations; Juvenile Diabetes Research Foundation United States of America; University of Alberta; Horizon 2020; KU Leuven; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"Cell biology; Endoplasmic reticulum; Biology; Signal transduction; Glucose-regulated protein; Apoptosis; Secretion; Beta cell; Secretory pathway; Unfolded protein response; Golgi apparatus; Islet; Biochemistry; Insulin; Endocrinology","score_opus":0.008252994243500044,"score_gpt":0.22061178603234194,"score_spread":0.2123587917888419,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2925670234","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997251,0.0008281696,0.00003823326,0.00024404118,0.00007648615,0.00074365176,0.00007040879,0.000006075059,0.000741931],"genre_scores_gemma":[0.99878424,0.0003129017,0.00005110885,0.0002299632,0.000043230386,0.000057957724,0.00008688553,0.000017720346,0.0004160111],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989443,0.000062391286,0.00024087208,0.00036449247,0.00014739539,0.00024058757],"domain_scores_gemma":[0.999073,0.000026032938,0.00006528178,0.0003938985,0.000041738316,0.00040003483],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009575983,0.0001771734,0.00019798958,0.000056993777,0.000035272682,0.000021813265,0.00015493229,0.00006676484,0.000026816579],"category_scores_gemma":[0.00004314616,0.00013220035,0.00009282883,0.0001211462,0.000042692696,0.0000062314807,0.000039458715,0.000059379057,0.000023189903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015104464,0.00038841242,0.02549389,0.00064780965,0.000035416106,0.000015252734,0.00018633976,0.0017610159,0.968278,0.00012427868,0.00029590545,0.0012632248],"study_design_scores_gemma":[0.0039192624,0.00036493415,0.020620966,0.00013091508,0.00017497232,0.0000021990122,0.0003500501,0.0024660404,0.9710033,0.00004830768,0.0005342183,0.00038486868],"about_ca_topic_score_codex":0.000062159204,"about_ca_topic_score_gemma":0.000017786826,"teacher_disagreement_score":0.0048729233,"about_ca_system_score_codex":0.000008946828,"about_ca_system_score_gemma":0.00015530443,"threshold_uncertainty_score":0.53909737},"labels":[],"label_agreement":null},{"id":"W2936932699","doi":"10.1038/s41419-019-1567-4","title":"Influenza a virus-triggered autophagy decreases the pluripotency of human-induced pluripotent stem cells","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; Children's Hospital Research Institute of Manitoba; University of Manitoba; Research Manitoba","funders":"Canadian Institutes of Health Research; Government of Canada; University of Manitoba; Research Manitoba","keywords":"Induced pluripotent stem cell; Biology; Autophagy; Embryonic stem cell; Cell biology; Stem cell; Cellular differentiation; Virology; Immunology; Genetics; Gene; Apoptosis","score_opus":0.016475491942808878,"score_gpt":0.25314695395404624,"score_spread":0.23667146201123737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2936932699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98782283,0.010840706,0.00006534622,0.000015117548,0.00009639462,0.00034589236,0.000039128096,0.000008686107,0.00076587376],"genre_scores_gemma":[0.9985241,0.00050732907,0.0000397905,0.00018883859,0.00007284506,0.00001664629,0.000035117464,0.000018439587,0.00059684436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990147,0.00007224374,0.000244522,0.00031916707,0.000150403,0.00019901778],"domain_scores_gemma":[0.999023,0.000022087037,0.00012494146,0.00045559005,0.000076752476,0.0002975937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108027976,0.0001638841,0.00015016494,0.000036061163,0.00009264597,0.000027221533,0.00015241193,0.000084907595,0.00003626114],"category_scores_gemma":[0.000022204866,0.00012259629,0.000114866365,0.000055533277,0.00004282183,0.000004675867,0.00009661416,0.00005549521,0.000013687905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012137246,0.000115631185,0.009060653,0.00007668366,0.000018970977,0.0000030369365,0.000036581474,0.00006954145,0.9891071,0.00011656302,0.000047421152,0.0012264436],"study_design_scores_gemma":[0.0008760683,0.00026642784,0.019663552,0.000016732643,0.00007163418,3.1915096e-7,0.000057675177,0.00013371544,0.97510594,0.0004500226,0.0031733362,0.00018460133],"about_ca_topic_score_codex":0.000059230482,"about_ca_topic_score_gemma":0.0000051445218,"teacher_disagreement_score":0.014001185,"about_ca_system_score_codex":0.000006687584,"about_ca_system_score_gemma":0.00012491802,"threshold_uncertainty_score":0.49993315},"labels":[],"label_agreement":null},{"id":"W2937040782","doi":"10.1038/s41419-019-1570-9","title":"BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Associazione Italiana per la Ricerca sul Cancro; Regione Campania","keywords":"Biology; Cancer research; Epigenetics; Leukemia; Myeloid leukemia; Cell growth; DNA methylation; STAT5; Cell biology; Signal transduction; Genetics; Gene expression; Gene","score_opus":0.00942012460394837,"score_gpt":0.2089875046771361,"score_spread":0.19956738007318772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937040782","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98535746,0.0022171258,0.00071066985,0.00006136103,0.000242673,0.0003025225,0.000036039626,0.000029551098,0.01104258],"genre_scores_gemma":[0.98884284,0.00035009865,0.0002850327,0.00017698287,0.00020048585,0.000012067479,0.0007288049,0.00002987436,0.009373807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888754,0.0000654967,0.00021396448,0.0004287432,0.00014778925,0.00025644095],"domain_scores_gemma":[0.999062,0.000011925347,0.0001076138,0.00037835148,0.00006587419,0.00037421417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009861509,0.00019004096,0.00013092747,0.000053185136,0.00011872023,0.00004995972,0.00008195534,0.00011257707,0.00010966706],"category_scores_gemma":[0.000019066756,0.00018767461,0.00007829304,0.000108018736,0.000044531007,0.000013724878,0.00008264928,0.000090415684,0.000111528534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015404593,0.00011443146,0.0041106394,0.00012331505,0.0000039144875,0.000006086278,0.00003294365,0.000040881445,0.9875831,0.00010177337,0.0073734154,0.00035545597],"study_design_scores_gemma":[0.0029391674,0.0003881638,0.007910075,0.00005662308,0.000043685137,0.00000436095,0.00018213376,0.00086816034,0.9420735,0.0006965072,0.04413504,0.00070256373],"about_ca_topic_score_codex":0.000011735078,"about_ca_topic_score_gemma":0.0000016285991,"teacher_disagreement_score":0.04550958,"about_ca_system_score_codex":0.000023732306,"about_ca_system_score_gemma":0.00013269248,"threshold_uncertainty_score":0.7653149},"labels":[],"label_agreement":null},{"id":"W2940054047","doi":"10.1038/s41419-019-1529-x","title":"Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Instituto Nacional de Ciência e Tecnologia de Neurociência Translacional; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Inflammation; Synapse; Cognitive impairment; Oligomer; Neuroscience; Cognitive decline; Immunology; Cognition; Medicine; Biology; Dementia; Chemistry; Internal medicine; Disease","score_opus":0.013517445468662084,"score_gpt":0.25089376064983593,"score_spread":0.23737631518117386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2940054047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99706227,0.000008615179,0.0002541899,0.00094460987,0.00012791353,0.0013508513,0.00004797801,0.00007130107,0.0001322929],"genre_scores_gemma":[0.99575454,0.000011378244,0.000026404487,0.0038389901,0.000043955723,0.00006894601,0.00001828452,0.00001698786,0.00022053909],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983256,0.00024401078,0.00027714824,0.00066485896,0.00022668605,0.00026170057],"domain_scores_gemma":[0.998664,0.00021313466,0.00006435389,0.00019188283,0.000057843437,0.00080874393],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020919339,0.00019866902,0.00016106141,0.0002420289,0.00011889045,0.00010996801,0.00006973793,0.000046387373,0.00007844014],"category_scores_gemma":[0.00085952866,0.00020397699,0.000034607514,0.00031018996,0.000024048162,0.00029033676,0.000101802085,0.000108357155,0.00019038361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005503155,0.00008413853,0.048657157,0.00008724483,8.754541e-7,0.00004894211,0.0003564727,0.00007684296,0.948776,0.00054054667,0.000043468834,0.00077801873],"study_design_scores_gemma":[0.001703631,0.0003510463,0.19968887,0.000034439254,0.000014357768,0.00000876734,0.00003291087,0.0011105613,0.7964116,0.00025560014,0.00010715087,0.00028112138],"about_ca_topic_score_codex":0.000049533846,"about_ca_topic_score_gemma":0.00006920224,"teacher_disagreement_score":0.15236443,"about_ca_system_score_codex":0.000037642363,"about_ca_system_score_gemma":0.00009851177,"threshold_uncertainty_score":0.831794},"labels":[],"label_agreement":null},{"id":"W2943663735","doi":"10.1038/s41419-019-1593-2","title":"Beta1 integrin blockade overcomes doxorubicin resistance in human T-cell acute lymphoblastic leukemia","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université Laval","funders":"Government of Canada; Canadian Institutes of Health Research; Université Laval","keywords":"Integrin; Matrigel; Doxorubicin; Cancer research; Extracellular matrix; Biology; Cell biology; Immunology; Chemistry; Cell; Chemotherapy; Biochemistry; Angiogenesis","score_opus":0.009791343089212168,"score_gpt":0.26470288730153163,"score_spread":0.2549115442123195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943663735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9688151,0.0026836344,0.000019525014,0.0001903275,0.00005169864,0.0005893062,0.000023114178,0.000042667667,0.027584642],"genre_scores_gemma":[0.9525115,0.00029153985,0.00017885065,0.00043340653,0.000051145285,0.000025910145,0.00006508391,0.00003852204,0.046404053],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981287,0.00006727442,0.00030275216,0.00056417374,0.00042897076,0.0005081246],"domain_scores_gemma":[0.99816686,0.00011406356,0.00005612115,0.00056276546,0.00005545257,0.0010447325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013509406,0.0002519757,0.00036809122,0.0002553625,0.000068311776,0.000046134504,0.00016396513,0.00009752876,0.0005155495],"category_scores_gemma":[0.000078590005,0.00021794088,0.00011357039,0.0002369959,0.000077805074,0.00006996358,0.00014783865,0.00030394315,0.00028008877],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029387348,0.00080137263,0.42741784,0.002050762,0.000042871096,0.0028940935,0.00028715437,0.000029305578,0.55715185,0.0006812203,0.0052940142,0.0004107722],"study_design_scores_gemma":[0.024955992,0.0008039187,0.8403299,0.0009866027,0.00057076325,0.000020902258,0.0003704382,0.002251889,0.10749961,0.0027967317,0.018201848,0.0012113958],"about_ca_topic_score_codex":0.00007581405,"about_ca_topic_score_gemma":0.000024617962,"teacher_disagreement_score":0.44965225,"about_ca_system_score_codex":0.0002954214,"about_ca_system_score_gemma":0.00051110226,"threshold_uncertainty_score":0.8887371},"labels":[],"label_agreement":null},{"id":"W2946218146","doi":"10.1038/s41419-019-1615-0","title":"Smad7:β-catenin complex regulates myogenic gene transcription","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; York University","keywords":"Myogenesis; Biology; Cell biology; Chromatin immunoprecipitation; Skeletal muscle; Transcription factor; Chromatin; Myocyte; Beta-catenin; Regulation of gene expression; Transcriptional regulation; Catenin; Reporter gene; Gene; Gene expression; Signal transduction; Wnt signaling pathway; Promoter; Genetics; Endocrinology","score_opus":0.012315328633566375,"score_gpt":0.21666995109194884,"score_spread":0.20435462245838246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946218146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923956,0.0064284103,0.00014529926,0.000039671497,0.00008420778,0.0002011467,0.00006726083,0.000027306356,0.00061108975],"genre_scores_gemma":[0.9963483,0.000109309,0.00025795487,0.00031319656,0.00011893985,0.000016410384,0.00074707373,0.000024284853,0.0020645203],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991317,0.000033543947,0.00013977704,0.0003766113,0.00009766574,0.00022070976],"domain_scores_gemma":[0.9991918,0.0000059774047,0.000039444236,0.0002940163,0.000036760237,0.00043196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045036388,0.00015810013,0.000110159635,0.000029754052,0.000069436974,0.000033585962,0.00011532875,0.000067436595,0.00014720423],"category_scores_gemma":[0.000017427807,0.0001531538,0.000099582416,0.000034992463,0.00004467869,0.000004701854,0.000041097766,0.000035167966,0.00006910971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027715456,0.00010646097,0.019558776,0.00008563701,0.000019915005,0.0000063092366,0.000018441997,0.00010491275,0.9784566,0.000031465446,0.0009186064,0.00041570762],"study_design_scores_gemma":[0.0024509213,0.00023665298,0.19578809,0.00002818619,0.00020465071,0.0000067364685,0.000052797663,0.0009005472,0.77449125,0.00052471063,0.02464145,0.0006739906],"about_ca_topic_score_codex":0.0000053063654,"about_ca_topic_score_gemma":9.952399e-7,"teacher_disagreement_score":0.20396535,"about_ca_system_score_codex":0.000006413348,"about_ca_system_score_gemma":0.00008902438,"threshold_uncertainty_score":0.6245431},"labels":[],"label_agreement":null},{"id":"W2947575755","doi":"10.1038/s41419-019-1648-4","title":"Elevated VMP1 expression in acute myeloid leukemia amplifies autophagy and is protective against venetoclax-induced apoptosis","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cancer Center, University of Colorado; Universitair Medisch Centrum Groningen; ZonMw; University of Alberta","keywords":"Autophagy; Myeloid leukemia; Haematopoiesis; Chemistry; Cell biology; CD34; Apoptosis; Myeloid; Progenitor cell; Leukemia; Cancer research; Stem cell; Biology; Molecular biology; Immunology; Biochemistry","score_opus":0.010982707006233796,"score_gpt":0.2504490690227823,"score_spread":0.2394663620165485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947575755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995949,0.0017380548,0.000026504553,0.00006815629,0.00006691875,0.0011197051,0.000040635507,0.00007025996,0.00092081213],"genre_scores_gemma":[0.9971676,0.00057058205,0.000070012364,0.0011747043,0.000050666982,0.00011893602,0.000057953566,0.000031384232,0.00075819116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987545,0.000048094254,0.00020792498,0.00048533065,0.00018991843,0.00031421217],"domain_scores_gemma":[0.9988354,0.000030143143,0.0000719173,0.00033500692,0.000043392516,0.00068417017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006398309,0.00024901834,0.00031870237,0.00012628568,0.00008566335,0.0000348516,0.00006747184,0.00012257125,0.00009772982],"category_scores_gemma":[0.000027129789,0.00020778345,0.00007457834,0.00013724057,0.000047037265,0.00013198647,0.000063457876,0.00018226299,0.000037957714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030942739,0.00022130404,0.07305313,0.00048432645,0.000091759815,0.00016793185,0.0012833962,0.000010259663,0.91770035,0.00006569608,0.00023545492,0.0035921142],"study_design_scores_gemma":[0.0058874916,0.000310272,0.44321257,0.0003259434,0.00017787448,0.0000041033236,0.0002716347,0.0015463646,0.54634356,0.0012765859,0.00027429906,0.00036930447],"about_ca_topic_score_codex":0.000038506772,"about_ca_topic_score_gemma":5.076365e-7,"teacher_disagreement_score":0.37135682,"about_ca_system_score_codex":0.00014741065,"about_ca_system_score_gemma":0.0003997057,"threshold_uncertainty_score":0.8473163},"labels":[],"label_agreement":null},{"id":"W2950141679","doi":"10.1038/s41419-019-1372-0","title":"Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Deutsche Krebshilfe; Ludwig-Maximilians-Universität München; Medizinischen Fakultät, Ludwig-Maximilians-Universität München; China Scholarship Council; Studienstiftung des Deutschen Volkes; Deutsche Forschungsgemeinschaft","keywords":"Gene knockdown; Enhancer; Biology; FLI1; Molecular biology; Gene; Gene expression; RNA interference; Transcription factor; Cancer research; Cell biology; Genetics; RNA","score_opus":0.012746635338714852,"score_gpt":0.2375229291989886,"score_spread":0.22477629386027376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950141679","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830734,0.0135259405,0.000008580351,0.0005472227,0.000047666956,0.00035415043,0.000012355315,0.000017547982,0.0024130982],"genre_scores_gemma":[0.9986552,0.00024526168,0.000084787825,0.00063713396,0.000054265638,0.000016137894,0.000024336672,0.000012425793,0.0002704371],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99931407,0.00002480139,0.0001481551,0.00018750736,0.00015013164,0.00017532297],"domain_scores_gemma":[0.9992832,0.00010359483,0.000047607966,0.00020061243,0.00004416942,0.0003208437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007492498,0.00011178641,0.00017279075,0.00003401304,0.00006001526,0.000013635886,0.000042999407,0.000026295324,0.00010122895],"category_scores_gemma":[0.00009909412,0.00006764295,0.00008772109,0.00006751722,0.000032033622,0.00003735528,0.00004650865,0.000057999856,0.0000368587],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012400285,0.00039238515,0.99518025,0.00031378257,0.000025910278,0.00006660769,0.00017592919,0.0000016154063,0.0015169445,0.00058536,0.00035905692,0.0012581815],"study_design_scores_gemma":[0.0037269858,0.00022311154,0.9810584,0.0002741724,0.00045376996,0.000008883994,0.0003152308,0.00046833296,0.011738985,0.0007158533,0.0008197249,0.00019652683],"about_ca_topic_score_codex":0.0000671932,"about_ca_topic_score_gemma":5.0640995e-7,"teacher_disagreement_score":0.015581776,"about_ca_system_score_codex":0.000015341668,"about_ca_system_score_gemma":0.000073362266,"threshold_uncertainty_score":0.27583992},"labels":[],"label_agreement":null},{"id":"W2955888829","doi":"10.1038/s41419-019-1687-x","title":"The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2α and IRE1α/XBP-1 in colorectal cancer","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Tunicamycin; Unfolded protein response; Apoptosis; Colorectal cancer; Cancer research; Signal transduction; Programmed cell death; Cancer; Medicine; Cell biology; Biology; Internal medicine; Biochemistry","score_opus":0.00490880787612755,"score_gpt":0.22023466790775453,"score_spread":0.215325860031627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2955888829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910368,0.0083971135,0.000026534279,0.00010453065,0.000037412356,0.00020309012,0.000072175135,0.000004891456,0.000117505835],"genre_scores_gemma":[0.99734944,0.0023411864,0.000019727695,0.000060002978,0.000056881127,0.000030289766,0.00005678026,0.000012863292,0.00007285328],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992627,0.000038629092,0.00011464245,0.00033198603,0.000067946465,0.00018408973],"domain_scores_gemma":[0.99949217,0.000039239607,0.000048636728,0.00009692272,0.00002712693,0.00029591154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000042674128,0.00015400896,0.0001246374,0.000028370374,0.00010455081,0.00010235287,0.000045778645,0.00004925883,0.000008584219],"category_scores_gemma":[0.000018248305,0.00010461293,0.000022337857,0.000025306184,0.0001065461,0.000014523068,0.00009738614,0.000069448615,4.6376775e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007205504,0.000035072804,0.96647966,0.00014133613,0.0000348118,0.0000049095215,0.000069379086,0.00003906436,0.029757002,0.000012552095,0.000028984792,0.002676668],"study_design_scores_gemma":[0.0038496144,0.0006278094,0.82482994,0.0003352678,0.0003848999,0.000008896943,0.0016829389,0.0027628364,0.16396724,0.0003114899,0.0005460448,0.0006930068],"about_ca_topic_score_codex":0.00016099593,"about_ca_topic_score_gemma":0.00005435169,"teacher_disagreement_score":0.14164971,"about_ca_system_score_codex":0.0000060603893,"about_ca_system_score_gemma":0.000034105127,"threshold_uncertainty_score":0.42659914},"labels":[],"label_agreement":null},{"id":"W2964762750","doi":"10.1038/s41419-019-1802-z","title":"Modifying PTEN recruitment promotes neuron survival, regeneration, and functional recovery after CNS injury","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Rehabilitation Institute; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; University of Toronto; Canadian Institute for Advanced Research","keywords":"PTEN; PDZ domain; Tensin; Axon; Cancer research; Neuroprotection; Regeneration (biology); Biology; Ischemia; Cell biology; Axon guidance; Medicine; Neuroscience; PI3K/AKT/mTOR pathway; Internal medicine; Signal transduction","score_opus":0.025505713394088966,"score_gpt":0.24772120125932126,"score_spread":0.2222154878652323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964762750","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935549,0.0047444436,0.0004547367,0.000139312,0.00031868,0.00030025092,0.00006880243,0.000010956831,0.00040791192],"genre_scores_gemma":[0.9960382,0.0005215655,0.00011609723,0.000631695,0.00024849115,0.000091491245,0.0001670068,0.00001831684,0.002167118],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99921674,0.0000416467,0.00010986995,0.00038099068,0.00009783632,0.00015290215],"domain_scores_gemma":[0.9994623,0.000009571737,0.00003796061,0.00021673257,0.000043235665,0.00023021706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007668604,0.00012995327,0.00008607464,0.000024626373,0.00005980886,0.000046854144,0.00003726179,0.00006295175,0.00006671343],"category_scores_gemma":[0.000030712225,0.00012214098,0.00004035927,0.000025266796,0.000026950116,0.000009318857,0.000067307905,0.000046431036,0.00000967069],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026459994,0.00019437117,0.15130399,0.00028595535,0.000059705588,0.000015588284,0.000038664897,0.0003272778,0.8343791,0.00006367113,0.0047408873,0.0059447945],"study_design_scores_gemma":[0.007038541,0.0037383416,0.39054424,0.0002563152,0.0005568278,0.00002205847,0.00009789678,0.005079992,0.38864398,0.0036513866,0.1975234,0.0028470068],"about_ca_topic_score_codex":0.0000052469472,"about_ca_topic_score_gemma":0.0000018793309,"teacher_disagreement_score":0.44573513,"about_ca_system_score_codex":0.000011764535,"about_ca_system_score_gemma":0.00010210995,"threshold_uncertainty_score":0.4980764},"labels":[],"label_agreement":null},{"id":"W2969019290","doi":"10.1038/s41419-019-1847-z","title":"Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"European Regional Development Fund; Canada Research Chairs; Science Foundation Ireland; Irish Research Council; European Commission; Trinity College Dublin; University of Galway; Health Research Board; National University of Ireland","keywords":"Inflammasome; Cell biology; Innate immune system; AIM2; Signal transduction; Caspase 1; Priming (agriculture); Pyroptosis; Multiprotein complex; Biology; Chemistry; Inflammation; Immune system; Immunology; Biochemistry","score_opus":0.006069171415107656,"score_gpt":0.22031708704610842,"score_spread":0.21424791563100076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969019290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955525,0.0028296397,0.000025332223,0.000026153273,0.00002400209,0.00021020237,0.000016563512,0.0000044561034,0.0013111854],"genre_scores_gemma":[0.99935085,0.00024012533,0.000043280437,0.000031742646,0.000024122213,0.000009146362,0.000047065096,0.000010051684,0.000243614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994132,0.000024487059,0.0001391553,0.00021472169,0.00007757097,0.0001308543],"domain_scores_gemma":[0.999546,0.0000048213624,0.000120003235,0.00014779971,0.000063639774,0.0001177329],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007073515,0.000109818764,0.00013172075,0.000038494774,0.000036798243,0.000013582915,0.00003923518,0.0000652987,0.0000064359033],"category_scores_gemma":[0.00004071801,0.000101502425,0.00004508779,0.000044251858,0.00006791567,0.000017193355,0.000060515362,0.000039349958,0.0000010880925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000388723,0.00008964495,0.02683869,0.0004725062,0.00000915773,0.0000018067632,0.00010873926,0.0000059380495,0.9674771,0.00001623282,0.000024020688,0.0045674285],"study_design_scores_gemma":[0.0009313356,0.00019740395,0.042793028,0.000059315385,0.00003813461,8.781002e-7,0.00015738296,0.00011415458,0.95521086,0.00010275089,0.00024556415,0.00014918695],"about_ca_topic_score_codex":0.000005971478,"about_ca_topic_score_gemma":7.063148e-7,"teacher_disagreement_score":0.015954338,"about_ca_system_score_codex":0.0000026024697,"about_ca_system_score_gemma":0.00012023767,"threshold_uncertainty_score":0.41391486},"labels":[],"label_agreement":null},{"id":"W2969420666","doi":"10.1038/s41419-019-1843-3","title":"NudC-like protein 2 restrains centriole amplification by stabilizing HERC2","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Natural Science Foundation of China","keywords":"Centrosome; Centriole; Biology; Cell biology; Gene knockdown; Gene duplication; Mitosis; Cell cycle; Gene; Genetics","score_opus":0.005701316477306605,"score_gpt":0.20940925057783136,"score_spread":0.20370793410052476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969420666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99486953,0.002867188,0.0005942837,0.00007215604,0.00004917724,0.00041783266,0.00009638871,0.000013133505,0.001020308],"genre_scores_gemma":[0.99558514,0.00034773233,0.00015586168,0.00032415622,0.000047827896,0.000026955766,0.0005621664,0.000017426815,0.002932719],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928164,0.000027238391,0.000109342946,0.00032530326,0.00006271815,0.00019376751],"domain_scores_gemma":[0.9993505,0.0000034967222,0.000039997798,0.00029518086,0.000028514667,0.0002823513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000510961,0.00011411353,0.0000752057,0.00001477164,0.000051371448,0.000031384163,0.000081768245,0.000071497096,0.000029112109],"category_scores_gemma":[0.000021140366,0.000111191475,0.00004606084,0.000028276932,0.00002383312,0.000004426654,0.000045709014,0.00004698961,0.000025699908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008813993,0.00010061503,0.013494247,0.000077286306,0.0000061114697,0.0000014086031,0.000016794456,0.0000057003585,0.98346853,0.0001446475,0.0019294875,0.00066704035],"study_design_scores_gemma":[0.004236435,0.00054159755,0.035162244,0.00011934736,0.00013124487,0.000005103909,0.0004440364,0.0010136466,0.53616476,0.0008794105,0.41989505,0.0014071518],"about_ca_topic_score_codex":0.00001377804,"about_ca_topic_score_gemma":0.000002572164,"teacher_disagreement_score":0.4473038,"about_ca_system_score_codex":0.000009360443,"about_ca_system_score_gemma":0.00008111466,"threshold_uncertainty_score":0.45342568},"labels":[],"label_agreement":null},{"id":"W2976804353","doi":"10.1038/s41419-019-1968-4","title":"Targeting a moonlighting function of aldolase induces apoptosis in cancer cells","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Narodowym Centrum Nauki","keywords":"Aldolase A; Cancer cell; Biology; Cell biology; Actin; Glycolysis; Gene silencing; Cell growth; Apoptosis; Cancer; Enzyme; Biochemistry; Genetics; Gene","score_opus":0.00769821897457924,"score_gpt":0.22547436785096714,"score_spread":0.2177761488763879,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2976804353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98656577,0.012233861,0.00004674024,0.000016892238,0.0005110843,0.0001475586,0.000035270456,0.0000043155146,0.00043852712],"genre_scores_gemma":[0.9969603,0.0019517278,0.00006567094,0.0001772626,0.00034467923,0.000019737347,0.00004440685,0.000011382016,0.00042483633],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934757,0.00002420626,0.00014178247,0.00025133512,0.00006951935,0.00016560646],"domain_scores_gemma":[0.9995917,0.00000646738,0.000066975816,0.00013266201,0.00003184054,0.00017033175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007173431,0.00010153844,0.00012199884,0.000041256757,0.000025507978,0.000010480776,0.000050929797,0.000058931804,0.000038524046],"category_scores_gemma":[0.000021324402,0.0000959939,0.00004926431,0.00005656527,0.000017285787,0.000006015119,0.00004450721,0.000047039437,0.000003297687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019537697,0.000064177344,0.016769465,0.00012419709,0.000008168689,2.641206e-7,0.00004047112,0.00018522605,0.9804046,0.00001095902,0.00055756693,0.0016394898],"study_design_scores_gemma":[0.0014426165,0.00009279152,0.017730342,0.00004808023,0.000081128914,1.5929983e-7,0.00019614719,0.00017531474,0.9601275,0.000063658976,0.019779153,0.0002631209],"about_ca_topic_score_codex":0.00010922102,"about_ca_topic_score_gemma":0.0000056793524,"teacher_disagreement_score":0.020277152,"about_ca_system_score_codex":0.0000058201313,"about_ca_system_score_gemma":0.00010654022,"threshold_uncertainty_score":0.39145178},"labels":[],"label_agreement":null},{"id":"W2978781448","doi":"10.1038/s41419-019-1987-1","title":"Impaired Wnt/β-catenin pathway leads to dysfunction of intestinal regeneration during necrotizing enterocolitis","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Burman University; Heart and Stroke Foundation; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Hospital for Sick Children; Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; National Institute for Health and Care Research; Government of Canada; Thrasher Research Fund","keywords":"Wnt signaling pathway; Necrotizing enterocolitis; Regeneration (biology); Intestinal epithelium; Intestinal Disorder; Intestinal mucosa; Biology; Stem cell; Enterocolitis; Homeostasis; LGR5; Organoid; Cell biology; Medicine; Cancer research; Immunology; Internal medicine; Pathology; Epithelium; Signal transduction; Disease","score_opus":0.013638829924900824,"score_gpt":0.23908654089312664,"score_spread":0.22544771096822583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978781448","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759406,0.00018418285,0.00022055782,0.0004955105,0.0003334023,0.0005041628,0.000025358551,0.000055631925,0.00058712054],"genre_scores_gemma":[0.99853426,0.000010126622,0.00025769684,0.0005289532,0.00013080992,0.000038279217,0.000057619334,0.00001504272,0.0004272166],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99914694,0.00004643845,0.0002244232,0.00023471919,0.00012210938,0.00022534671],"domain_scores_gemma":[0.9992804,0.000019032625,0.000074213356,0.000120545374,0.00007411724,0.00043169607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081915845,0.00011108727,0.00014452395,0.00011670635,0.00011912674,0.000035334484,0.000035533256,0.00003748674,0.00008558197],"category_scores_gemma":[0.000043308293,0.000113733186,0.000053105923,0.0000865516,0.000013343663,0.00012796331,0.00002308938,0.000069650894,0.000050657563],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004387721,0.00033695684,0.34785315,0.002111212,0.0000054803545,0.000033172262,0.0008037399,0.00013175006,0.63962126,0.0012303665,0.0011931367,0.0022920608],"study_design_scores_gemma":[0.004762333,0.00090953126,0.5557481,0.0006665353,0.00006582508,0.000029848825,0.00027785465,0.0023968322,0.43280882,0.00090015004,0.0009653942,0.00046880185],"about_ca_topic_score_codex":0.000056544566,"about_ca_topic_score_gemma":0.000006472648,"teacher_disagreement_score":0.20789492,"about_ca_system_score_codex":0.000058133395,"about_ca_system_score_gemma":0.000042836567,"threshold_uncertainty_score":0.46379048},"labels":[],"label_agreement":null},{"id":"W2980241471","doi":"10.1038/s41419-019-1979-1","title":"Ca2+-dependent recruitment of voltage-gated sodium channels underlies bilirubin-induced overexcitation and neurotoxicity","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neonatal Health and Biochemistry","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Canada Research Chairs; Government of Canada","keywords":"Neuroscience; Neuroprotection; Neurotoxicity; Cell biology; Patch clamp; Chemistry; Downregulation and upregulation; Biology; Electrophysiology; Biochemistry; Toxicity","score_opus":0.04092786974176277,"score_gpt":0.29223867428242095,"score_spread":0.2513108045406582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980241471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968251,0.0010345948,0.0000137900015,0.00020628369,0.00013602058,0.0010149514,0.000045353318,0.000023226316,0.0007006986],"genre_scores_gemma":[0.99789685,0.00019087522,0.000025104877,0.0005388507,0.000049003746,0.000022215921,0.000070180715,0.000010280116,0.0011966246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999168,0.000016962193,0.00017951788,0.00027331166,0.00017418135,0.0001880627],"domain_scores_gemma":[0.99896777,0.000039690287,0.00006970126,0.0001831541,0.0000563383,0.00068335986],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007044628,0.00012873583,0.00018681285,0.00004307615,0.000042318086,0.000011773762,0.000029587625,0.00006118474,0.00004260457],"category_scores_gemma":[0.000048951024,0.0001062372,0.000036711885,0.000052504383,0.000032335593,0.00004350337,0.00003700818,0.00008563302,0.000008898907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005419455,0.0010584258,0.15096861,0.011809276,0.000045562527,0.00019836974,0.00042157335,0.000004571548,0.81936264,0.00037566308,0.00037287662,0.009962982],"study_design_scores_gemma":[0.01177965,0.0018720217,0.29163882,0.00051011017,0.0003299557,0.000036091926,0.0007721435,0.0023169923,0.6870942,0.0017512351,0.001298801,0.000599941],"about_ca_topic_score_codex":0.000058026297,"about_ca_topic_score_gemma":0.0000011244343,"teacher_disagreement_score":0.14067023,"about_ca_system_score_codex":0.000024680761,"about_ca_system_score_gemma":0.00017442321,"threshold_uncertainty_score":0.43322274},"labels":[],"label_agreement":null},{"id":"W2980318507","doi":"10.1038/s41419-019-2019-x","title":"Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; University of Toronto; Dalhousie University; Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; McGill University Health Centre; Government of Canada; McGill University","keywords":"XIAP; Inhibitor of apoptosis; Apoptosis; Oocyte; Cell biology; Caspase-9; Caspase; Caspase 3; Biology; Chemistry; Programmed cell death; Biochemistry; Embryo","score_opus":0.006102749106518193,"score_gpt":0.2202413994613877,"score_spread":0.2141386503548695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980318507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988726,0.00040572035,0.00014199868,0.00003576529,0.000020488276,0.00041681214,0.000011045876,0.0000034464554,0.00009213088],"genre_scores_gemma":[0.99904156,0.000053719006,0.0002418575,0.000029581683,0.000043773354,0.000026394151,0.00011533428,0.000008646657,0.0004391128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993917,0.000034538487,0.00015749298,0.00020935244,0.000090802685,0.00011610877],"domain_scores_gemma":[0.99967486,0.000006436028,0.000056912304,0.0001352694,0.000023454495,0.00010306503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108454995,0.000101758786,0.00009150618,0.000044635683,0.000046234185,0.000018002436,0.00005292223,0.00006233703,0.000003829677],"category_scores_gemma":[0.000014740713,0.00007680318,0.000027357739,0.00003498021,0.000020917882,0.0000065853,0.00006220383,0.000041251446,0.0000014674443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026810565,0.000075279575,0.011737718,0.00023569181,0.000009301981,0.0000018503189,0.00023063949,0.000012754217,0.9848688,0.000042191703,0.0000069828284,0.0025106887],"study_design_scores_gemma":[0.0011330186,0.000106007385,0.1275478,0.000043052944,0.000024613322,9.072605e-7,0.00015616426,0.00014940459,0.87034786,0.00005434179,0.00028256138,0.0001543003],"about_ca_topic_score_codex":0.000007578153,"about_ca_topic_score_gemma":0.000002726977,"teacher_disagreement_score":0.115810074,"about_ca_system_score_codex":0.000008413617,"about_ca_system_score_gemma":0.000041607986,"threshold_uncertainty_score":0.31319427},"labels":[],"label_agreement":null},{"id":"W2982338995","doi":"10.1038/s41419-019-2107-y","title":"The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Novartis Pharma; Ministero dello Sviluppo Economico; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; Cancer Research UK; Ontario Ministry of Economic Development and Innovation; Wellcome Trust; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; National Institute for Health and Care Research; Massachusetts General Hospital; Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi; European Commission; Pfizer","keywords":"Apoptosis; Chemistry; Cancer research; DNA damage; Pharmacology; In vivo; Biochemistry; Biology; DNA","score_opus":0.009506125954275782,"score_gpt":0.25400206728736624,"score_spread":0.24449594133309047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982338995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9756023,0.02142028,0.00001722302,0.0010373757,0.000102227816,0.0012508006,0.00005075052,0.000034165954,0.00048487418],"genre_scores_gemma":[0.9916023,0.00078310625,0.000044466997,0.0036460392,0.00012089407,0.00012009015,0.000011105825,0.000024996078,0.0036470203],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990806,0.000033121487,0.00016172013,0.00026683786,0.0001490963,0.0003086083],"domain_scores_gemma":[0.9991037,0.00010312845,0.000042148433,0.0003056832,0.0000497399,0.00039554838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012479594,0.00016409175,0.00022205533,0.000055830445,0.00009825818,0.00003803851,0.000056867306,0.00004506735,0.00007008827],"category_scores_gemma":[0.000029536845,0.000103731516,0.00013311005,0.00008422508,0.000054650398,0.00005865889,0.000021413387,0.00008065204,0.00004314553],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.09187636,0.004502349,0.6937151,0.005436895,0.0015761202,0.0014259926,0.01315867,0.000026649392,0.047959264,0.036029875,0.017571678,0.08672105],"study_design_scores_gemma":[0.02903458,0.0016018874,0.7814234,0.00031947988,0.0011428343,0.00003560108,0.0018962228,0.008452826,0.038771655,0.0255605,0.110659845,0.0011011554],"about_ca_topic_score_codex":0.000005794347,"about_ca_topic_score_gemma":0.0000013072287,"teacher_disagreement_score":0.093088165,"about_ca_system_score_codex":0.000015346941,"about_ca_system_score_gemma":0.00014656405,"threshold_uncertainty_score":0.42300487},"labels":[],"label_agreement":null},{"id":"W2984483109","doi":"10.1038/s41419-019-2103-2","title":"Browning of white adipose tissue after a burn injury promotes hepatic steatosis and dysfunction","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; Sunnybrook Hospital; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Canadian Institutes of Health Research; NIH Clinical Center; U.S. Department of Health and Human Services; National Institutes of Health; Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"Steatosis; Browning; White adipose tissue; Adipose tissue; Medicine; Burn injury; Pathology; Internal medicine; Endocrinology; Biology; Chemistry; Biochemistry; Surgery","score_opus":0.006976713768819183,"score_gpt":0.22917339543864285,"score_spread":0.22219668166982368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2984483109","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9844204,0.013907606,0.000055658482,0.000093153016,0.00007800731,0.00045256846,0.000020350964,0.000023338953,0.0009488772],"genre_scores_gemma":[0.99422455,0.00029064747,0.00023255356,0.0002517019,0.00007483849,0.000022217142,0.000020079604,0.000017631945,0.004865763],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992981,0.000023541672,0.00015824995,0.00023179522,0.00012482263,0.00016348119],"domain_scores_gemma":[0.9991794,0.00001788292,0.000052533112,0.0002067671,0.000045684337,0.00049769966],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006189898,0.00013168892,0.00024736352,0.0000827626,0.000041165993,0.000011268219,0.000021710417,0.00004964118,0.00023570369],"category_scores_gemma":[0.00004075122,0.000106864034,0.000037191283,0.000070473296,0.000036153066,0.000100067395,0.000048072794,0.00006851699,0.000027566919],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014272676,0.00022458352,0.9555461,0.0016221477,0.000049314258,0.00006562721,0.0011103426,4.524646e-7,0.023158466,0.00007205061,0.00014080596,0.016582867],"study_design_scores_gemma":[0.003352464,0.0008836761,0.9706249,0.0004955625,0.0017503828,0.000019771433,0.00014550758,0.000375734,0.012645921,0.00047582577,0.008894075,0.0003361458],"about_ca_topic_score_codex":0.000023482355,"about_ca_topic_score_gemma":8.0583203e-7,"teacher_disagreement_score":0.016246721,"about_ca_system_score_codex":0.000006401555,"about_ca_system_score_gemma":0.00005766712,"threshold_uncertainty_score":0.4357789},"labels":[],"label_agreement":null},{"id":"W2987059351","doi":"10.1038/s41419-019-2074-3","title":"RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activity","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Vetenskapsrådet; National Institutes of Health; Fonds de Recherche du Québec - Santé; Knut och Alice Wallenbergs Stiftelse; Cancerfonden","keywords":"Translation (biology); Phosphorylation; Biology; Apoptosis; Translational regulation; Suppressor; Cell biology; Messenger RNA; eIF2; Cancer research; Cancer; Gene; Genetics","score_opus":0.023803766486874767,"score_gpt":0.2952008047155048,"score_spread":0.27139703822863004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2987059351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99590343,0.0018957629,0.0014036885,0.00006523611,0.000034866534,0.00033661514,0.000099279765,0.000003620292,0.00025748028],"genre_scores_gemma":[0.9979754,0.00044544306,0.00006776584,0.000027251774,0.000055132776,0.00002125722,0.000073362535,0.000008308685,0.0013260773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994851,0.00001895646,0.00007837864,0.00019413239,0.00009059319,0.00013283659],"domain_scores_gemma":[0.99961656,0.00001019636,0.000038055055,0.00012688192,0.00005130632,0.00015700309],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007134392,0.00006881716,0.00008110387,0.00002299372,0.000036972117,0.0000120279865,0.000046607718,0.000046643814,0.000015676187],"category_scores_gemma":[0.000024568424,0.000063060965,0.000052902084,0.000020511936,0.0000125610695,0.000009968285,0.000017467093,0.000024677174,0.0000014672348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044152525,0.000055137407,0.021681435,0.00019143788,0.000010239129,3.5202467e-7,0.000007738835,0.00025477912,0.97205734,0.00002470084,0.000043897013,0.0052314172],"study_design_scores_gemma":[0.0018118318,0.0002065352,0.08976313,0.000023628663,0.000032613087,2.2514587e-7,0.000014571508,0.022203127,0.8850786,0.00012482848,0.00057621533,0.000164669],"about_ca_topic_score_codex":0.000016143733,"about_ca_topic_score_gemma":0.0000041280223,"teacher_disagreement_score":0.08697871,"about_ca_system_score_codex":0.0000047350495,"about_ca_system_score_gemma":0.00006489106,"threshold_uncertainty_score":0.25715515},"labels":[],"label_agreement":null},{"id":"W2990870824","doi":"10.1038/s41419-019-2132-x","title":"Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; McGill University; University Health Network; University of Toronto; Montreal Neurological Institute and Hospital; Toronto Western Hospital; Canada Research Chairs","funders":"Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Mitophagy; Parkin; Cell biology; Programmed cell death; Apoptosis; Cancer research; Autophagy; Biology; Chemistry; Genetics; Medicine","score_opus":0.009167255125084981,"score_gpt":0.22878723335323706,"score_spread":0.21961997822815207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990870824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9616383,0.032935448,0.000008772954,0.0001240281,0.00018128294,0.0006044962,0.00007569226,0.000099480116,0.0043325396],"genre_scores_gemma":[0.9830471,0.0023472838,0.00005994345,0.00117283,0.00013571272,0.000027852202,0.00015369503,0.00004820882,0.013007357],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99835247,0.00006228939,0.00026100595,0.0005683015,0.0003052529,0.00045069543],"domain_scores_gemma":[0.9979349,0.000068714304,0.00010562852,0.00045211008,0.00006719922,0.001371465],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011634211,0.0003170029,0.00040093687,0.00009464088,0.00012659728,0.00005579119,0.000091799775,0.00013823954,0.00048155343],"category_scores_gemma":[0.000035894034,0.0002699434,0.00014817192,0.000091094145,0.00005258055,0.00009938799,0.00007682824,0.00013787489,0.00014284815],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018085884,0.0016268794,0.9491867,0.00074649137,0.00022982848,0.0010080239,0.00026644967,0.000008532674,0.041502386,0.00031112813,0.0016400021,0.0016650009],"study_design_scores_gemma":[0.011009631,0.0005255345,0.93219006,0.00018211418,0.00094038015,0.000017995588,0.00011495258,0.00085391186,0.047102615,0.0029141179,0.003483262,0.0006654361],"about_ca_topic_score_codex":0.000029531016,"about_ca_topic_score_gemma":0.000001110667,"teacher_disagreement_score":0.030588167,"about_ca_system_score_codex":0.000045502464,"about_ca_system_score_gemma":0.00019205973,"threshold_uncertainty_score":0.99997526},"labels":[],"label_agreement":null},{"id":"W2992595197","doi":"10.1038/s41419-019-2166-0","title":"11th Tuscany Retreat on Cancer Research and Apoptosis: Genetic profiling, resistance mechanisms and novel treatment concepts in cancer and neurodegeneration","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Sunnybrook Hospital; Princess Margaret Cancer Centre; University of British Columbia; University Health Network; University of Toronto; Sunnybrook Health Science Centre","funders":"Medizinische Universität Wien; Tel Aviv University; Universität Wien","keywords":"Neurodegeneration; Apoptosis; Biology; Profiling (computer programming); Cancer; Cancer research; Bioinformatics; Neuroscience; Computational biology; Medicine; Genetics; Disease; Pathology; Computer science","score_opus":0.0336249289143935,"score_gpt":0.32288723854366413,"score_spread":0.28926230962927063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2992595197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.952965,0.04519462,0.0000070804326,0.0005570619,0.000066762695,0.00094243296,0.00006025059,0.000014137699,0.0001926612],"genre_scores_gemma":[0.966096,0.02814411,0.00012444684,0.000223273,0.00010678738,0.0003150572,0.000016388243,0.000025831027,0.0049481285],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99867564,0.00006853153,0.00017297413,0.0005613771,0.00021607117,0.00030541973],"domain_scores_gemma":[0.9991268,0.00007926045,0.000044838755,0.00024107956,0.000066985056,0.00044106954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109416294,0.0002055998,0.0002832139,0.00013803404,0.00015759942,0.00004956357,0.00003087471,0.00006763045,0.000022787084],"category_scores_gemma":[0.000033948025,0.00016779582,0.000024528701,0.00011109545,0.000119980636,0.0000614783,0.000034079265,0.00011260527,0.0000011853233],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.025343219,0.001356862,0.72640705,0.0025692473,0.000095108546,0.00017373933,0.0019336196,0.00008587441,0.21225828,0.0020212368,0.00053122465,0.027224516],"study_design_scores_gemma":[0.01783786,0.0027432025,0.8844084,0.0014872551,0.0003791362,0.000019898682,0.00056524674,0.002295463,0.08413378,0.00053587847,0.0049077077,0.00068613],"about_ca_topic_score_codex":0.0008193737,"about_ca_topic_score_gemma":0.0002822186,"teacher_disagreement_score":0.15800136,"about_ca_system_score_codex":0.00012781715,"about_ca_system_score_gemma":0.0003208198,"threshold_uncertainty_score":0.6842515},"labels":[],"label_agreement":null},{"id":"W2992856652","doi":"10.1038/s41419-019-2134-8","title":"Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Tel Aviv University; New Brunswick Innovation Foundation; Fondation de la recherche en santé du Nouveau-Brunswick; Université de Moncton; Cancer Research Institute","keywords":"Mitochondrion; Biology; Proto-oncogene tyrosine-protein kinase Src; Cell biology; Kinase; Subcellular localization; Cancer research; Cancer cell; Mitochondrial DNA; Cancer; Biochemistry; Cytoplasm; Genetics; Gene","score_opus":0.005671351089258721,"score_gpt":0.221343824396793,"score_spread":0.21567247330753428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2992856652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99255,0.0026403565,0.0006353082,0.000113908165,0.002644936,0.00039209457,0.00045222303,0.0000129630325,0.0005581731],"genre_scores_gemma":[0.9940994,0.001123349,0.00032421894,0.00045723154,0.0011672198,0.00005130063,0.00016806944,0.000027465538,0.0025817521],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892,0.00007162809,0.00020607025,0.00047472588,0.000103920815,0.00022364498],"domain_scores_gemma":[0.9990104,0.000021482052,0.00010756763,0.00031574134,0.00009519024,0.00044962708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000035148812,0.0001949471,0.00020803403,0.0000573848,0.00007774159,0.000025971232,0.000087502725,0.00024525455,0.0002792113],"category_scores_gemma":[0.000035174122,0.00017809593,0.00008883052,0.00006113229,0.0001070883,0.000008513527,0.0000949221,0.00013566947,0.00001602426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018408595,0.00012680663,0.01581252,0.00013903627,0.00002614765,0.000011574183,0.00003018907,0.00006803528,0.97763693,0.00011545164,0.0030571697,0.0011352953],"study_design_scores_gemma":[0.023574794,0.001908059,0.09464606,0.00034719377,0.00102047,0.00011920275,0.00034612196,0.0009235747,0.7502639,0.0010898787,0.1234018,0.0023589204],"about_ca_topic_score_codex":0.000039925173,"about_ca_topic_score_gemma":0.000009585636,"teacher_disagreement_score":0.22737299,"about_ca_system_score_codex":0.0000065910194,"about_ca_system_score_gemma":0.00017469662,"threshold_uncertainty_score":0.7262541},"labels":[],"label_agreement":null},{"id":"W2994521826","doi":"10.1038/s41419-019-2144-6","title":"Extensive protein S-nitrosylation associated with human pancreatic ductal adenocarcinoma pathogenesis","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China; Guangzhou University; Guangzhou University of Chinese Medicine; Chinese Academy of Sciences; Hunan Provincial Science and Technology Department","keywords":"Biology; Cancer research; Signal transduction; Carcinogenesis; S-Nitrosylation; Cell biology; STAT3; Cancer; Biochemistry","score_opus":0.009432946917829034,"score_gpt":0.2171696817869892,"score_spread":0.20773673486916017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2994521826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959844,0.0015165262,0.000025730933,0.00005886945,0.00002130618,0.00091751973,0.000020919279,0.000059661023,0.0013951019],"genre_scores_gemma":[0.9959466,0.0000119022725,0.0000871665,0.00025575692,0.00007109737,0.000046457913,0.00013669815,0.00002767001,0.0034166386],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99914086,0.000049365495,0.00012148311,0.00027725485,0.00018816395,0.00022289528],"domain_scores_gemma":[0.9991141,0.000044914297,0.00006517589,0.0002193955,0.00008902622,0.0004673747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006918881,0.00015721224,0.0002335161,0.00006922556,0.00007972677,0.000020224013,0.000028965687,0.000049861123,0.000089605346],"category_scores_gemma":[0.00011356185,0.00011821119,0.000055348122,0.00010455858,0.000028735023,0.00006457749,0.00001700355,0.000077085046,0.000059722424],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005391747,0.0001802632,0.9097974,0.00024740773,0.000039760278,0.00044078202,0.000056429813,0.000003113146,0.088463336,0.00006920969,0.000053416745,0.00010973137],"study_design_scores_gemma":[0.003180998,0.0005036991,0.99276805,0.00018423756,0.0004886043,0.000012367744,0.00006419692,0.00024796303,0.0020637393,0.00029079415,0.000021617223,0.00017375137],"about_ca_topic_score_codex":0.000021967138,"about_ca_topic_score_gemma":0.0000010694368,"teacher_disagreement_score":0.08639959,"about_ca_system_score_codex":0.000032729553,"about_ca_system_score_gemma":0.000099271725,"threshold_uncertainty_score":0.48205122},"labels":[],"label_agreement":null},{"id":"W2997327234","doi":"10.1038/s41419-019-2189-6","title":"Correction: Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β","year":2020,"lang":"en","type":"erratum","venue":"Cell Death and Disease","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Inflammasome; Cell biology; Computer science; Chemistry; Biology; Biochemistry; Receptor","score_opus":0.008386039094135298,"score_gpt":0.22747190816992466,"score_spread":0.21908586907578936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2997327234","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97356564,0.016954212,0.000060302686,0.0000993887,0.0014508377,0.00037264815,0.000083340754,0.000013921049,0.007399711],"genre_scores_gemma":[0.98714185,0.0025150569,0.000025477913,0.00006804028,0.0004038665,0.000029585224,0.00075590186,0.00003326027,0.009026951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988776,0.00005278939,0.000276212,0.00044696793,0.00015408116,0.00019235392],"domain_scores_gemma":[0.9990446,0.0000073215906,0.000354592,0.0002069523,0.00013874662,0.00024779138],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000715302,0.00027577204,0.00032810157,0.00007238883,0.00009171985,0.000032723645,0.000077026016,0.0003004035,0.000007203126],"category_scores_gemma":[0.00016783713,0.00027295668,0.00011368263,0.000092495415,0.00014705089,0.000017506623,0.00012529448,0.00022411134,7.767985e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002079385,0.00038256374,0.002749287,0.0056185005,0.000111422894,0.000038906277,0.0004413424,0.0000103152,0.8155252,0.000009627229,0.15180555,0.021227907],"study_design_scores_gemma":[0.0024040823,0.0010961695,0.0153842075,0.0009837962,0.00062882615,0.000009294829,0.00051491696,0.00074916705,0.90592945,0.00015102843,0.071008235,0.0011408407],"about_ca_topic_score_codex":0.000011357079,"about_ca_topic_score_gemma":0.0000028416466,"teacher_disagreement_score":0.09040425,"about_ca_system_score_codex":0.000007665232,"about_ca_system_score_gemma":0.00057662034,"threshold_uncertainty_score":0.9999723},"labels":[],"label_agreement":null},{"id":"W3003182814","doi":"10.1038/s41419-020-2280-z","title":"Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neonatal and fetal brain pathology","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Labex Immuno-Oncology; High-end Foreign Experts Recruitment Plan of China; European Research Area Network on Cardiovascular Diseases; Institut Universitaire de France; Vetenskapsrådet; Ligue Contre le Cancer; Agence Nationale de la Recherche; Association pour la Recherche sur le Cancer; Seerave Foundation; National Natural Science Foundation of China; Institut National Du Cancer; Institut National de la Santé et de la Recherche Médicale; Swedish Cancer Foundation; Institut Gustave-Roussy; Barncancerfonden; Göteborgs Universitet; Fondation Leducq; European Commission","keywords":"Apoptosis-inducing factor; Neuroprotection; Biology; Cre recombinase; Genetically modified mouse; Apoptosis; Transgene; Cell biology; Caspase; Gene knockin; Programmed cell death; Molecular biology; Neuroscience; Genetics; Gene","score_opus":0.01615632670732109,"score_gpt":0.24744253542899086,"score_spread":0.23128620872166977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003182814","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962666,0.0018140038,0.000023747452,0.0009583355,0.000027395778,0.0001967829,0.00013758444,0.000024313857,0.0005512031],"genre_scores_gemma":[0.99766195,0.000071573384,0.00018753405,0.0018050821,0.0000593638,0.0000075732305,0.0000663792,0.00001391262,0.00012662122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917096,0.000026021171,0.000202298,0.00029752203,0.0001184302,0.00018477805],"domain_scores_gemma":[0.99912393,0.000072776566,0.000061423736,0.00012274303,0.00002012498,0.00059899106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000033124437,0.00013973474,0.00023975922,0.00006398422,0.000024490702,0.0000057562575,0.00006193232,0.00007448897,0.000071924434],"category_scores_gemma":[0.00032022552,0.000117549964,0.00006376269,0.000117642005,0.000057630376,0.00007531646,0.00009867037,0.00015488635,0.000010014513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001152653,0.00007729657,0.039659303,0.0005524618,0.0000059642452,0.00006492081,0.00072962436,5.778752e-7,0.95017684,0.000021526963,0.00069565076,0.006863174],"study_design_scores_gemma":[0.0033774516,0.00041577104,0.0858896,0.0004222776,0.000067459994,0.00000986534,0.0003702262,0.00033420706,0.90583193,0.000355158,0.0025979453,0.0003281212],"about_ca_topic_score_codex":0.00001999722,"about_ca_topic_score_gemma":1.7831546e-7,"teacher_disagreement_score":0.046230294,"about_ca_system_score_codex":0.0000098085,"about_ca_system_score_gemma":0.00007280599,"threshold_uncertainty_score":0.47935486},"labels":[],"label_agreement":null},{"id":"W3004699970","doi":"10.1038/s41419-020-2302-x","title":"Nogo-A-targeting antibody promotes visual recovery and inhibits neuroinflammation after retinal injury","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Foundation for Innovation; Government of Canada","keywords":"Neuroinflammation; Retinal; Antibody; Neuroscience; Retina; Cell biology; Retinal degeneration; Medicine; Cancer research; Immunology; Biology; Inflammation; Ophthalmology","score_opus":0.013716668968530984,"score_gpt":0.2543871630214588,"score_spread":0.2406704940529278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004699970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998108,0.00032517893,0.0001537195,0.000792753,0.00008806626,0.00021722633,0.00003056199,0.000055995075,0.00022849756],"genre_scores_gemma":[0.99816334,0.00012380148,0.00007494725,0.0012384608,0.00025093343,0.000010483191,0.000025330115,0.000013418886,0.0000992946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990131,0.000102488404,0.00017107687,0.00040881304,0.00013549319,0.00016901833],"domain_scores_gemma":[0.9993634,0.00004272997,0.00006328841,0.00006940415,0.000019529587,0.00044161238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006559557,0.00013272502,0.00009456835,0.00003562932,0.00017177424,0.00013159522,0.000040557617,0.000036614012,0.000021774065],"category_scores_gemma":[0.00040590155,0.00011631019,0.00003339818,0.000094954,0.00005352806,0.00034604844,0.000068110196,0.000094059294,0.000018666442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006565236,0.00004674927,0.009633471,0.00017277616,7.2664403e-7,0.000076976525,0.00012217149,0.0000050664594,0.9875189,0.00008754307,0.00019077687,0.0014882986],"study_design_scores_gemma":[0.00042915612,0.00038777982,0.0132590225,0.000039215756,0.00003709449,0.0000045933257,0.000015249387,0.0077367937,0.9768272,0.00045977614,0.0005256574,0.00027848323],"about_ca_topic_score_codex":0.0000010654395,"about_ca_topic_score_gemma":1.2223909e-7,"teacher_disagreement_score":0.010691742,"about_ca_system_score_codex":0.000004375635,"about_ca_system_score_gemma":0.00004137385,"threshold_uncertainty_score":0.4742992},"labels":[],"label_agreement":null},{"id":"W3005425030","doi":"10.1038/s41419-020-2305-7","title":"G protein-coupled kisspeptin receptor induces metabolic reprograming and tumorigenesis in estrogen receptor-negative breast cancer","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; London Health Sciences Centre; University of Toronto","funders":"National Institute of General Medical Sciences; National Cancer Institute; Government of Canada; Heart and Stroke Foundation of Canada; Canadian Institutes of Health Research; National Institute for Health and Care Research; Rutgers Cancer Institute of New Jersey; Robert Wood Johnson Foundation","keywords":"Triple-negative breast cancer; Cancer research; Kisspeptin; Glutaminolysis; Estrogen receptor; Breast cancer; Glutamine; Biology; Glutaminase; Metastasis; Progesterone receptor; Internal medicine; Carcinogenesis; Estrogen receptor alpha; Invadopodia; Endocrinology; Cancer; Cancer cell; Medicine; Hormone; Biochemistry","score_opus":0.01712999701005783,"score_gpt":0.2492082848512943,"score_spread":0.23207828784123646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3005425030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9749921,0.017729994,0.000010745809,0.0056544673,0.000043213375,0.0013247402,0.00007697663,0.00007240928,0.00009533495],"genre_scores_gemma":[0.9967824,0.0008183513,0.0010371774,0.00037030733,0.00042684036,0.00029894648,0.000021132444,0.000038544866,0.00020626718],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982527,0.00007860278,0.0002876747,0.00081309455,0.00022263001,0.00034530673],"domain_scores_gemma":[0.99845237,0.000041173513,0.00011450569,0.0002547463,0.0001113155,0.0010258836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016449793,0.00027617524,0.00049191806,0.0000929796,0.0000791363,0.000045500095,0.000072354516,0.00006207699,0.00014807614],"category_scores_gemma":[0.00046042097,0.00023701452,0.00007744958,0.00025209994,0.000117426775,0.00015266685,0.0000759704,0.00018583296,0.00001776748],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003761801,0.000479119,0.56360906,0.0005687165,0.0001550647,0.0001705932,0.0016976582,0.000006691026,0.3764729,0.00015632155,0.00012079294,0.052801263],"study_design_scores_gemma":[0.0061577503,0.0003025276,0.95663923,0.00022732263,0.0005355561,0.000017433795,0.0010105615,0.00089606264,0.031087618,0.00019198169,0.002315121,0.00061884307],"about_ca_topic_score_codex":0.00038326276,"about_ca_topic_score_gemma":0.0000050896765,"teacher_disagreement_score":0.39303014,"about_ca_system_score_codex":0.000039797567,"about_ca_system_score_gemma":0.00028484483,"threshold_uncertainty_score":0.96651715},"labels":[],"label_agreement":null},{"id":"W3011349461","doi":"10.1038/s41419-020-2371-x","title":"PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Foundation for the National Institutes of Health; Fundo para o Desenvolvimento das Ciências e da Tecnologia; Universidade de Macau; National Natural Science Foundation of China; Vanderbilt University","keywords":"Pancreatitis; Carcinogenesis; Inflammation; Cancer research; Inflammatory response; Pancreatic cancer; Medicine; Cell biology; Internal medicine; Biology; Cancer","score_opus":0.007788629933141841,"score_gpt":0.21327660981933771,"score_spread":0.20548797988619588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011349461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850162,0.013946043,0.00033412216,0.0002878286,0.000017535373,0.0001469813,0.000054770495,0.000014791742,0.00018171991],"genre_scores_gemma":[0.997597,0.0011794713,0.0003020842,0.0003322807,0.00010609431,0.000016974127,0.00014229272,0.000020353551,0.00030347888],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991783,0.000094828254,0.0001506821,0.00033127706,0.000082557715,0.0001623834],"domain_scores_gemma":[0.999179,0.000031990985,0.000057116416,0.00015129212,0.000033081673,0.0005475161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010830818,0.00014019477,0.00011810891,0.000016200915,0.000108294684,0.000041921612,0.000048861784,0.0000573271,0.000011383192],"category_scores_gemma":[0.00023738507,0.00013706168,0.00003469393,0.000038354556,0.000050009246,0.00000517461,0.00006676822,0.00003444042,0.0000031686236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005568485,0.000016734926,0.30922583,0.00008355306,0.000012065955,0.00001101389,0.00006810338,0.0000137455845,0.6882658,0.000012177246,0.00060811784,0.0011260104],"study_design_scores_gemma":[0.0018333152,0.00057153846,0.38427803,0.000036627152,0.00018019324,0.0000029281318,0.00014512108,0.0014754432,0.58918726,0.0004801983,0.021117866,0.00069150154],"about_ca_topic_score_codex":0.000007469454,"about_ca_topic_score_gemma":5.8270336e-7,"teacher_disagreement_score":0.09907858,"about_ca_system_score_codex":0.000004126202,"about_ca_system_score_gemma":0.00006182153,"threshold_uncertainty_score":0.55892134},"labels":[],"label_agreement":null},{"id":"W3014505500","doi":"10.1038/s41419-020-2405-4","title":"Histone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; V Foundation for Cancer Research; U.S. Department of Veterans Affairs; U.S. Department of Health and Human Services","keywords":"Demethylase; DNA repair; Cancer research; Histone; DNA damage; Ubiquitin; RAD51; Ubiquitin ligase; Biology; Chromatin; Prostate cancer; Ectopic expression; Chemistry; Cell biology; Molecular biology; DNA; Gene; Cancer; Genetics","score_opus":0.01986833149242749,"score_gpt":0.278940114980924,"score_spread":0.2590717834884965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014505500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9741375,0.024535239,0.000035888537,0.00036476477,0.000044517725,0.00044484064,0.00024912562,0.000041806492,0.00014635663],"genre_scores_gemma":[0.99723995,0.001590116,0.00046913401,0.00026300302,0.00004765027,0.000032239375,0.000018143277,0.000018932082,0.0003208191],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990785,0.000038397295,0.00025964496,0.00029219134,0.00018737794,0.00014387941],"domain_scores_gemma":[0.9988804,0.000039853257,0.00015359346,0.0001773464,0.00007335802,0.0006754345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000051070325,0.00015082113,0.00030398794,0.00004104034,0.000040398332,0.0000042973957,0.000035725912,0.000040235962,0.00008616599],"category_scores_gemma":[0.00005897897,0.000120038196,0.00007726394,0.0000922441,0.0001442877,0.00006422906,0.000024628558,0.00007114092,6.155686e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022325683,0.00016865453,0.0834964,0.002744418,0.00002082651,0.000031571853,0.0012811772,0.000002971953,0.90738904,0.000014518302,0.0024774147,0.00014045322],"study_design_scores_gemma":[0.0023601167,0.00014925245,0.018546317,0.00038002728,0.0001418748,3.2681018e-7,0.00009595236,0.00006373366,0.97613484,0.000086559885,0.0019122323,0.00012879666],"about_ca_topic_score_codex":0.000024440551,"about_ca_topic_score_gemma":0.0000013185434,"teacher_disagreement_score":0.068745784,"about_ca_system_score_codex":0.000027162536,"about_ca_system_score_gemma":0.00017797301,"threshold_uncertainty_score":0.48950157},"labels":[],"label_agreement":null},{"id":"W3019078212","doi":"10.1038/s41419-020-2458-4","title":"SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Alzheimer Nederland; Rijksuniversiteit Groningen; European Commission; Greater Cincinnati Foundation","keywords":"Cell biology; Glycolysis; Mitochondrion; Biology; Programmed cell death; Mitochondrial ROS; Mitophagy; Cellular respiration; Anaerobic glycolysis; Reactive oxygen species; Voltage-dependent anion channel; Biochemistry; Metabolism; Apoptosis; Autophagy; Bacterial outer membrane","score_opus":0.0072010532766380395,"score_gpt":0.2035121476807157,"score_spread":0.19631109440407768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019078212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98893434,0.008939663,0.00045689623,0.0009898795,0.00003709318,0.0002602878,0.00017116246,0.000015725136,0.00019496032],"genre_scores_gemma":[0.99539655,0.0014950105,0.00025972456,0.0022348834,0.000114287686,0.000027833852,0.00019122708,0.000026443511,0.00025402955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987855,0.000046324352,0.00019169028,0.0005450076,0.00012244274,0.00030902808],"domain_scores_gemma":[0.99869037,0.000008137293,0.0000438433,0.0002253575,0.000043001884,0.0009892975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059303988,0.00020763392,0.00021120893,0.00005389857,0.00006848192,0.00004999821,0.00010926668,0.00008594638,0.000017585202],"category_scores_gemma":[0.00011244531,0.00021331105,0.00004863293,0.000135069,0.00004268826,0.000006584752,0.00013467787,0.000070356255,0.0000074023696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021225954,0.0008569928,0.32159454,0.0012219135,0.00015972194,0.0003181024,0.007685953,0.0009390775,0.65549237,0.0001856069,0.008241921,0.0011812286],"study_design_scores_gemma":[0.0058546406,0.0007051105,0.3849991,0.0001207751,0.0006497719,0.000004682826,0.0011575171,0.0018525858,0.5589585,0.00064927986,0.04260957,0.0024384994],"about_ca_topic_score_codex":0.00002516535,"about_ca_topic_score_gemma":0.00012412053,"teacher_disagreement_score":0.09653389,"about_ca_system_score_codex":0.000004536467,"about_ca_system_score_gemma":0.0000795562,"threshold_uncertainty_score":0.8698572},"labels":[],"label_agreement":null},{"id":"W3020974403","doi":"10.1038/s41419-020-2533-x","title":"Taking aim with IAP antagonists at triple-negative breast cancer: a moving target no more?","year":2020,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"Canadian Cancer Society Research Institute; University of Ottawa","keywords":"Breast cancer; Triple-negative breast cancer; Cancer; Cancer research; Medicine; Oncology; Internal medicine","score_opus":0.016971813313164205,"score_gpt":0.27517152393088473,"score_spread":0.2581997106177205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020974403","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004765587,0.993612,0.00007452222,0.00005711923,0.00011726262,0.0009024528,0.0028836718,0.000029199226,0.0018472244],"genre_scores_gemma":[0.0026182733,0.99302065,0.00036522752,0.0003838505,0.0006800176,0.00031989487,0.001123374,0.0000926199,0.0013961128],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99814624,0.000111517904,0.0002905156,0.00085681654,0.00017605923,0.0004188694],"domain_scores_gemma":[0.9982347,0.000021549133,0.00035100864,0.00036469294,0.00007898888,0.00094906276],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006418548,0.0005687817,0.00077714626,0.00004600062,0.00022061146,0.00007362381,0.00023079009,0.00021122652,0.00017533894],"category_scores_gemma":[0.00006553399,0.00043851003,0.0002889424,0.00011186672,0.00011067547,0.000006072522,0.0002769478,0.00020852739,0.000034255914],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039010935,0.0005212794,0.0041397307,0.08139771,0.0011828914,0.001840991,0.00034041278,0.0000164137,0.0014583818,0.00009800159,0.011156083,0.893947],"study_design_scores_gemma":[0.000864121,0.0001455091,0.00010905824,0.0021889822,0.0007134688,0.00006776236,0.000014733033,0.00006152381,0.0004674115,0.000015080701,0.9945411,0.0008112654],"about_ca_topic_score_codex":0.000045164514,"about_ca_topic_score_gemma":0.0000052903374,"teacher_disagreement_score":0.983385,"about_ca_system_score_codex":0.000059542497,"about_ca_system_score_gemma":0.000893097,"threshold_uncertainty_score":0.99980664},"labels":[],"label_agreement":null},{"id":"W3020986724","doi":"10.1038/s41419-020-2500-6","title":"Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblasts","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Concordia University; Western University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Children's Health Research Institute","keywords":"Cytotrophoblast; Syncytiotrophoblast; Biology; Cell biology; Trophoblast; Histone; Cellular differentiation; Syncytium; Chromatin remodeling; Cell fusion; Histone deacetylase 2; Epigenetics; Histone deacetylase; Genetics; Placenta; Cell; Gene; Fetus","score_opus":0.007265753595558234,"score_gpt":0.22941939698474806,"score_spread":0.22215364338918983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020986724","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99573445,0.0038059503,0.00016299523,0.00003243721,0.000018629715,0.00016351462,0.00003207757,0.000002721613,0.00004719079],"genre_scores_gemma":[0.9989741,0.0006896091,0.00011474063,0.0000369451,0.000043252803,0.000005582704,0.00009608821,0.000007764232,0.00003192558],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995055,0.000027923625,0.00011576986,0.00021383709,0.000054002227,0.00008295661],"domain_scores_gemma":[0.9996129,0.0000047945628,0.00004751913,0.00006256929,0.000016611248,0.0002556072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000025142646,0.00008509619,0.00008551145,0.000021753993,0.000037992864,0.000010405136,0.0000223635,0.00004739091,0.0000041221765],"category_scores_gemma":[0.00001723956,0.00008302205,0.000019283727,0.000023396271,0.000038235245,0.0000031623003,0.000057408535,0.000029256962,2.5256765e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016292496,0.00006388162,0.052330263,0.00009253126,0.0000030024746,0.000002805602,0.000099974764,0.0000075883686,0.9465915,0.000009900594,0.000019020548,0.0006166274],"study_design_scores_gemma":[0.0013719056,0.00028372792,0.14091909,0.000011095862,0.000033482047,2.1201556e-7,0.00004817824,0.00073507713,0.8562087,0.00008306991,0.00018001707,0.00012546181],"about_ca_topic_score_codex":0.000009182348,"about_ca_topic_score_gemma":0.000005109954,"teacher_disagreement_score":0.0903828,"about_ca_system_score_codex":0.000004109461,"about_ca_system_score_gemma":0.000019461633,"threshold_uncertainty_score":0.3385541},"labels":[],"label_agreement":null},{"id":"W3022104575","doi":"10.1038/s41419-020-2551-8","title":"Cisplatin-induced ototoxicity in organotypic cochlear cultures occurs independent of gap junctional intercellular communication","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Organ of Corti; Ototoxicity; Connexin; Gap junction; Cisplatin; Hair cell; Cell biology; Carbenoxolone; Biology; Cochlea; Apoptosis; Intracellular; Chemistry; Anatomy; Biochemistry; Genetics; Chemotherapy","score_opus":0.020926141876290834,"score_gpt":0.2509027237245712,"score_spread":0.22997658184828035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3022104575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973106,0.0013283821,0.00013222228,0.00024479526,0.000025545063,0.00013672335,0.000022679797,0.0000052575047,0.00079381844],"genre_scores_gemma":[0.99879295,0.00018044036,0.000051298517,0.00066352746,0.000043035878,0.000008008562,0.00020895095,0.0000067770407,0.000045003482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939615,0.00006661995,0.00015603314,0.00021791953,0.00005774462,0.00010554143],"domain_scores_gemma":[0.9995305,0.000010219013,0.000042912256,0.00017922885,0.00003953202,0.00019763569],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057143974,0.00009698385,0.000110796325,0.00002229505,0.00003590185,0.000008115518,0.0001087023,0.00008828472,0.000054522687],"category_scores_gemma":[0.00009679976,0.00008776879,0.000046305664,0.000046405155,0.000045532703,0.0000030828514,0.00011387319,0.00008625334,0.000004060873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078460755,0.00016271582,0.08981082,0.00007916658,0.00001787753,0.000007828384,0.0001986293,0.000029876817,0.90737724,0.00044599507,0.00042980278,0.0006554621],"study_design_scores_gemma":[0.0060565714,0.001280969,0.46186695,0.00007823605,0.00013996984,0.000008239826,0.0010092291,0.0020352595,0.5102395,0.0011193207,0.015269405,0.0008963589],"about_ca_topic_score_codex":0.000028894827,"about_ca_topic_score_gemma":0.000020515983,"teacher_disagreement_score":0.39713773,"about_ca_system_score_codex":0.0000059925887,"about_ca_system_score_gemma":0.00007013622,"threshold_uncertainty_score":0.35791075},"labels":[],"label_agreement":null},{"id":"W3022457072","doi":"10.1038/s41419-020-2498-9","title":"MCL-1Matrix maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Université de Montréal; University of Ottawa","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; Krembil Foundation; Government of Canada; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Bioenergetics; Cell biology; Mitochondrion; Stress (linguistics); Biology; Chemistry","score_opus":0.018227735613236054,"score_gpt":0.23944541617840692,"score_spread":0.22121768056517088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3022457072","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9858176,0.0007487914,0.010388067,0.0012086787,0.00049754814,0.00018126993,0.00082820427,0.000022894163,0.00030691182],"genre_scores_gemma":[0.9960835,0.0001892686,0.00023251024,0.0020213795,0.00050510996,0.000016091879,0.00068899617,0.000015829119,0.00024732365],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989289,0.00012648945,0.0001600394,0.00045263313,0.000090081194,0.00024188148],"domain_scores_gemma":[0.9989413,0.00002678413,0.000043952376,0.00014921432,0.000045249508,0.0007935108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000039251358,0.0001742026,0.00014588807,0.000021119677,0.00017579357,0.000041001338,0.000072183066,0.00011833178,0.00009356566],"category_scores_gemma":[0.00017326063,0.00016823149,0.00006600443,0.00004471414,0.00012203978,0.000006488628,0.000090841415,0.00016282257,0.000008410458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048041326,0.00011970039,0.009749201,0.000088410816,0.000021711467,0.00001311194,0.00006664418,0.000034100558,0.9768432,0.0013089167,0.011237504,0.000037132657],"study_design_scores_gemma":[0.018617095,0.0036190385,0.045574456,0.000092905764,0.0011379987,0.00006744349,0.0029531422,0.0025842972,0.7732894,0.0063442406,0.14181902,0.0039009626],"about_ca_topic_score_codex":0.000035506768,"about_ca_topic_score_gemma":0.00004067209,"teacher_disagreement_score":0.20355374,"about_ca_system_score_codex":0.000006273939,"about_ca_system_score_gemma":0.000106039,"threshold_uncertainty_score":0.68602806},"labels":[],"label_agreement":null},{"id":"W3025183262","doi":"10.1038/s41419-020-2564-3","title":"Ciao1 interacts with Crumbs and Xpd to regulate organ growth in Drosophila","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Research Foundation of Korea; National Research Foundation","keywords":"RNA interference; Gene knockdown; Biology; Mutant; Cell biology; Programmed cell death; Genetic screen; Cell growth; Imaginal disc; Genetics; Apoptosis; Gene; RNA","score_opus":0.00820825250459934,"score_gpt":0.21547135043643442,"score_spread":0.2072630979318351,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025183262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963165,0.0016455905,0.00025523588,0.00095042615,0.000014543197,0.00013269341,0.0000112876505,0.000005340569,0.0006683664],"genre_scores_gemma":[0.9981373,0.00028432626,0.00026442113,0.0010800475,0.000074382224,0.0000063657303,0.000044404336,0.000013143631,0.00009559348],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99943507,0.000019748022,0.00008800638,0.00027852046,0.00005342196,0.0001252582],"domain_scores_gemma":[0.9993157,0.0000052309797,0.000022215962,0.00009393252,0.000027833587,0.0005350875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000032857773,0.000098672994,0.00008027937,0.000022976856,0.000030967796,0.0000305588,0.000043337943,0.000037127375,0.000004607414],"category_scores_gemma":[0.0000699141,0.000086752334,0.000014012769,0.000060926683,0.000020720347,0.000003613119,0.00006699377,0.00003553047,0.0000026914097],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013307222,0.00011996428,0.34952685,0.00019536093,0.000016559221,0.000085694264,0.00044220753,0.00010872766,0.6451915,0.00025231493,0.00033968658,0.0023904063],"study_design_scores_gemma":[0.002517875,0.0010907886,0.6015007,0.00005935135,0.00006323815,0.0000020808354,0.00008581886,0.0005098926,0.386171,0.0017156556,0.005681555,0.0006020293],"about_ca_topic_score_codex":0.00000870177,"about_ca_topic_score_gemma":0.0000068921913,"teacher_disagreement_score":0.2590205,"about_ca_system_score_codex":0.0000029086648,"about_ca_system_score_gemma":0.000038831313,"threshold_uncertainty_score":0.35376576},"labels":[],"label_agreement":null},{"id":"W3033850471","doi":"10.1038/s41419-020-2634-6","title":"Hypoxia-induced shift in the phenotype of proteasome from 26S toward immunoproteasome triggers loss of immunoprivilege of mesenchymal stem cells","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Yarmouk University; Government of Canada","keywords":"Mesenchymal stem cell; Proteasome; Immune system; Hypoxia (environmental); Immunology; Downregulation and upregulation; Transplantation; Biology; Human leukocyte antigen; Cancer research; Cell biology; Antigen; Chemistry; Medicine; Internal medicine","score_opus":0.021271513162691335,"score_gpt":0.22414787612697273,"score_spread":0.2028763629642814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033850471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924538,0.005667615,0.00006452018,0.00015707845,0.000048263344,0.0008191566,0.00040380817,0.0000061199034,0.00037961802],"genre_scores_gemma":[0.99928945,0.00020929007,0.00010983118,0.00016146703,0.000074861215,0.000053458014,0.0000657874,0.00002016641,0.000015658576],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852085,0.00018610751,0.00044750882,0.00036212994,0.00024183704,0.00024155974],"domain_scores_gemma":[0.99896246,0.000041772244,0.000250542,0.00044424564,0.00006309505,0.00023787456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020836327,0.00022077913,0.00035451874,0.000040475723,0.00003249273,0.000012030929,0.00040345822,0.00012766811,0.00003291449],"category_scores_gemma":[0.000067899295,0.00017322373,0.00016777578,0.00014759974,0.00012832014,0.000009859616,0.00014761378,0.00013759758,0.0000034657328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012763639,0.00025474268,0.004924189,0.00044095863,0.000040205032,0.000014935406,0.0011067124,0.000009218593,0.99078274,0.00013079883,0.000025257634,0.0009939047],"study_design_scores_gemma":[0.001617212,0.0005641009,0.017976753,0.000058837337,0.00007049927,4.822554e-7,0.0004367828,0.00005008548,0.9782252,0.0005072522,0.0002716353,0.00022121037],"about_ca_topic_score_codex":0.00012957664,"about_ca_topic_score_gemma":0.0000016603286,"teacher_disagreement_score":0.013052565,"about_ca_system_score_codex":0.0000056461686,"about_ca_system_score_gemma":0.00022903483,"threshold_uncertainty_score":0.70638585},"labels":[],"label_agreement":null},{"id":"W3035676622","doi":"10.1038/s41419-020-2654-2","title":"BIK drives an aggressive breast cancer phenotype through sublethal apoptosis and predicts poor prognosis of ER-positive breast cancer","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Cancer Society; Alberta Innovates - Health Solutions; Cure Brain Cancer Foundation; University of Alberta; Alberta Cancer Foundation; Pfizer","keywords":"Breast cancer; Apoptosis; Phenotype; Cancer; Cancer research; Oncology; Medicine; Internal medicine; Biology; Gene; Genetics","score_opus":0.013298990964080194,"score_gpt":0.2522522320594363,"score_spread":0.23895324109535612,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035676622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97531694,0.014684068,0.00009070833,0.004425553,0.00011408839,0.0008157179,0.0039589447,0.00007346588,0.0005205409],"genre_scores_gemma":[0.9940659,0.0032859924,0.00015774742,0.0018090497,0.0003157561,0.00014324169,0.00013522696,0.00005279812,0.00003429784],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984142,0.000058418475,0.00024883667,0.0006173029,0.00030809484,0.00035313293],"domain_scores_gemma":[0.9979495,0.00002677771,0.00020811874,0.00019193023,0.00023096913,0.0013927384],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000031611857,0.00030357312,0.0004164608,0.000055047516,0.000106595806,0.0000325786,0.000086661785,0.00011524746,0.00019642377],"category_scores_gemma":[0.000037694637,0.00026507743,0.000101150115,0.00022946845,0.000237598,0.00020397609,0.000090742076,0.00019340988,0.000002898005],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02526835,0.002879598,0.72625226,0.005971825,0.0015245228,0.0009836757,0.013170744,0.0004906523,0.17191565,0.00041132816,0.006876036,0.044255387],"study_design_scores_gemma":[0.014197432,0.0013956487,0.88363016,0.0027940073,0.0056122122,0.00011773701,0.0010431779,0.004770055,0.084582835,0.00027472468,0.00036034177,0.0012216402],"about_ca_topic_score_codex":0.00089600054,"about_ca_topic_score_gemma":0.000020026031,"teacher_disagreement_score":0.15737796,"about_ca_system_score_codex":0.00006273791,"about_ca_system_score_gemma":0.0005927323,"threshold_uncertainty_score":0.99998015},"labels":[],"label_agreement":null},{"id":"W3042239566","doi":"10.1038/s41419-020-02739-9","title":"NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Key Research and Development Program of China; Higher Education Discipline Innovation Project; National Natural Science Foundation of China","keywords":"Myosin; Cell biology; Cell migration; Hsp90; Chemistry; Cell; Biochemistry; Biology; Heat shock protein; Gene","score_opus":0.006160424279006858,"score_gpt":0.19250866418635226,"score_spread":0.1863482399073454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042239566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99129957,0.005664404,0.0018256984,0.0004156272,0.000025265195,0.00013135922,0.000053606516,0.0000114338245,0.0005730485],"genre_scores_gemma":[0.99736345,0.0008141339,0.0002315222,0.0007225078,0.00006046892,0.0000090459625,0.00022563718,0.000016511742,0.0005567162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994056,0.000018113726,0.000088262,0.0003002719,0.000059464004,0.00012829251],"domain_scores_gemma":[0.9993815,0.000005773431,0.000038153805,0.00012660306,0.000026825724,0.00042117113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000023667248,0.00011888071,0.00007647824,0.000011336266,0.00009864191,0.00005828622,0.000040737596,0.000044121898,0.000023828961],"category_scores_gemma":[0.000015091214,0.00010312552,0.00003029251,0.000032242162,0.000023888062,0.00000815138,0.00003322277,0.00004745857,0.0000024965263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026250182,0.000094247975,0.0026132555,0.000093402894,0.000011283073,0.000006880176,0.00013653503,0.000012146873,0.9916517,0.000036492558,0.0046307845,0.0004507848],"study_design_scores_gemma":[0.0015267164,0.0008113644,0.0010297035,0.000025263907,0.00015408176,0.0000048387283,0.00041612904,0.0061580436,0.8492974,0.0001382182,0.13993198,0.00050628104],"about_ca_topic_score_codex":0.000016097189,"about_ca_topic_score_gemma":0.0000059237273,"teacher_disagreement_score":0.14235431,"about_ca_system_score_codex":0.000003489512,"about_ca_system_score_gemma":0.000042934396,"threshold_uncertainty_score":0.42053366},"labels":[],"label_agreement":null},{"id":"W3044665335","doi":"10.1038/s41419-020-02803-4","title":"Bioactive DNA from extracellular vesicles and particles","year":2020,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":215,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Princess Margaret Cancer Foundation; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Cancer Research Society; American Society of Clinical Oncology; Conquer Cancer Foundation","keywords":"Biomarker; DNA; Extracellular vesicles; Extracellular vesicle; Biology; Microvesicles; Mediator; Cell biology; RNA; Computational biology; Extracellular; DNA damage; Chemistry; Gene; microRNA; Biochemistry","score_opus":0.021084575071042604,"score_gpt":0.26621237099198686,"score_spread":0.24512779592094425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044665335","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012416738,0.98598856,0.00013218034,0.000032622207,0.00006669581,0.00047981832,0.0007209176,0.00002852787,0.00013395824],"genre_scores_gemma":[0.0107521815,0.9870994,0.00034669638,0.0001134517,0.00037562958,0.000069926245,0.00095125736,0.00008125992,0.00021020368],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980724,0.00017037457,0.00034534978,0.00095326104,0.00014091839,0.0003177287],"domain_scores_gemma":[0.9978051,0.00005136416,0.00018065552,0.0005178436,0.000025935498,0.0014190853],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006717307,0.0004976861,0.0006343174,0.000039795697,0.00011163237,0.00010240374,0.00021810834,0.00024087387,0.000027572134],"category_scores_gemma":[0.00015357582,0.00045167038,0.0002786093,0.000069726775,0.00018587157,0.000007970751,0.00030404152,0.00015936501,0.000040270585],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019031462,0.00027109042,0.00037297973,0.005563461,0.00026039593,0.0005601767,0.000046963436,3.6105615e-7,0.008001136,0.00017252467,0.0012057344,0.98335487],"study_design_scores_gemma":[0.00042753216,0.00007040361,0.000086411725,0.0005270126,0.001591904,0.000005337723,0.000031956704,0.000031183314,0.0015380271,0.0006387849,0.9944332,0.0006182487],"about_ca_topic_score_codex":0.000007830342,"about_ca_topic_score_gemma":7.407837e-7,"teacher_disagreement_score":0.9932275,"about_ca_system_score_codex":0.000013407862,"about_ca_system_score_gemma":0.00031391508,"threshold_uncertainty_score":0.9997935},"labels":[],"label_agreement":null},{"id":"W3044717029","doi":"10.1038/s41419-020-02780-8","title":"Dianhydrogalactitol synergizes with topoisomerase poisons to overcome DNA repair activity in tumor cells","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Prevention of Organ Failure; Read Jones Christoffersen (Canada); Delmar (Canada); University of British Columbia","funders":"Mitacs","keywords":"Topoisomerase; DNA repair; DNA damage; DNA; Cell biology; Biology; Computational biology; Cancer research; Chemistry; Genetics","score_opus":0.008445914522321287,"score_gpt":0.2173544265003317,"score_spread":0.2089085119780104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044717029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977998,0.0005645865,0.00036329683,0.0005572751,0.000050758685,0.000250475,0.00009067753,0.000021689384,0.00030144668],"genre_scores_gemma":[0.99593925,0.00010063367,0.00017616332,0.0033960228,0.000106510546,0.000038445156,0.000020445605,0.000020848378,0.00020166847],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991704,0.000025889365,0.00008712011,0.00039943776,0.00008889896,0.00022823807],"domain_scores_gemma":[0.9989463,0.000007277721,0.000029666322,0.00021473659,0.00001765924,0.0007843513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000032776465,0.00015780421,0.00013541967,0.000027984177,0.00004706712,0.000026098398,0.00007684875,0.000037019938,0.000019171495],"category_scores_gemma":[0.000014833774,0.000140927,0.000062870204,0.00008501552,0.000020611968,0.0000063473594,0.00006950079,0.00006186125,0.000007843603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017555042,0.00018714517,0.0054336195,0.00009803865,0.000022464556,0.00014487693,0.00010866688,0.00013292622,0.99074006,0.00006291515,0.000614725,0.00069906533],"study_design_scores_gemma":[0.002235406,0.0010325976,0.011151913,0.00002995635,0.00009129666,0.0000045170136,0.00012226732,0.0005958592,0.94414735,0.00008586727,0.039907902,0.0005950936],"about_ca_topic_score_codex":0.00005471512,"about_ca_topic_score_gemma":0.000038991064,"teacher_disagreement_score":0.046592727,"about_ca_system_score_codex":0.000013230574,"about_ca_system_score_gemma":0.00012371122,"threshold_uncertainty_score":0.57468367},"labels":[],"label_agreement":null},{"id":"W3068150758","doi":"10.1038/s41419-020-02893-0","title":"Shedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Université de Montréal; Montreal Clinical Research Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs; Government of Canada","keywords":"Furin; Proprotein Convertases; Biology; Cell biology; Transmembrane protein; Transfection; Proprotein convertase; Cancer cell; Endosome; HEK 293 cells; Signal transducing adaptor protein; Cell culture; Cancer; Molecular biology; Biochemistry; Signal transduction; Genetics; Receptor; Enzyme","score_opus":0.01329775295831185,"score_gpt":0.2661137505445704,"score_spread":0.25281599758625856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3068150758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990887,0.007001042,0.0006676979,0.0003792124,0.000016084326,0.0005167925,0.00049166044,0.0000069977086,0.000033533874],"genre_scores_gemma":[0.9980389,0.00035662236,0.000014359967,0.000277941,0.000039608385,0.00012176603,0.0010684604,0.000011934138,0.00007041127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922544,0.000027843449,0.00017104954,0.00031853913,0.000089895504,0.00016726287],"domain_scores_gemma":[0.999482,0.0000042138395,0.000068036396,0.00015525789,0.000035571797,0.00025495063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005971964,0.0001272945,0.00012495747,0.000011576633,0.00004923846,0.000010466351,0.00009248368,0.00006356142,0.000065607084],"category_scores_gemma":[0.000017930011,0.00009371809,0.000048896527,0.000067078334,0.0000683615,0.0000044675603,0.000037228605,0.00006841891,3.6513367e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004945937,0.00007825323,0.13703904,0.00019162982,0.000010610428,0.0000026487812,0.00008980831,0.000014773838,0.8616369,0.000008462988,0.00006920627,0.00036408618],"study_design_scores_gemma":[0.0017810443,0.0001546923,0.06960929,0.00006293456,0.000118670825,3.044703e-7,0.00009209258,0.0012624726,0.9210336,0.000026433347,0.005576316,0.00028210127],"about_ca_topic_score_codex":0.00091325876,"about_ca_topic_score_gemma":0.00027248226,"teacher_disagreement_score":0.06742974,"about_ca_system_score_codex":0.0000120801205,"about_ca_system_score_gemma":0.00017308429,"threshold_uncertainty_score":0.38217127},"labels":[],"label_agreement":null},{"id":"W3070585844","doi":"10.1038/s41419-020-02907-x","title":"Chemotherapeutic resistance of head and neck squamous cell carcinoma is mediated by EpCAM induction driven by IL-6/p62 associated Nrf2-antioxidant pathway activation","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; McGill University","funders":"Biomedical Research Council; Medical Research Council; World Bank Group","keywords":"Epithelial cell adhesion molecule; Gene silencing; Cancer research; Head and neck squamous-cell carcinoma; Cisplatin; Small interfering RNA; Biology; Gene knockdown; Molecular biology; Chemistry; Cell culture; Cell adhesion molecule; Cell biology; Cancer; Transfection; Head and neck cancer; Chemotherapy; Gene; Biochemistry","score_opus":0.016697590228690117,"score_gpt":0.23031281730195707,"score_spread":0.21361522707326697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3070585844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98968333,0.0071571795,0.00006241691,0.0013638651,0.00003954726,0.00038717475,0.00071315846,0.000031963635,0.0005613808],"genre_scores_gemma":[0.99596655,0.00059514877,0.000053519845,0.0020106235,0.000049063565,0.000014219277,0.00036584793,0.00002914542,0.00091585977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883693,0.00004567866,0.00026166553,0.00038638423,0.00024637263,0.00022297092],"domain_scores_gemma":[0.99884385,0.000042303276,0.00017659292,0.0001616932,0.0000876901,0.00068790145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057960384,0.00019680406,0.00032458868,0.00004208785,0.000072805764,0.000019653125,0.000043743305,0.000091909154,0.00010233012],"category_scores_gemma":[0.00007694273,0.00018345317,0.00007382108,0.00019219409,0.000060404975,0.00008679952,0.00002217617,0.00013025702,0.00000448022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017519734,0.00068853213,0.07224649,0.001094051,0.000042951004,0.000017338454,0.000849894,0.0000011810894,0.8909603,0.000005228388,0.031148018,0.0011940825],"study_design_scores_gemma":[0.01531609,0.00094630936,0.21586256,0.00016832877,0.00092799956,0.0000018127332,0.00044098112,0.00091849105,0.72291315,0.00007334902,0.04176605,0.00066488335],"about_ca_topic_score_codex":0.00011346442,"about_ca_topic_score_gemma":0.0000049052896,"teacher_disagreement_score":0.16804712,"about_ca_system_score_codex":0.000053457617,"about_ca_system_score_gemma":0.00016330354,"threshold_uncertainty_score":0.74810034},"labels":[],"label_agreement":null},{"id":"W3080361388","doi":"10.1038/s41419-020-02905-z","title":"Regulation of epithelial-mesenchymal transition and organoid morphogenesis by a novel TGFβ-TCF7L2 isoform-specific signaling pathway","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cell biology; Gene isoform; Epithelial–mesenchymal transition; Transcription factor; Alternative splicing; Biology; Morphogenesis; Transforming growth factor; Signal transduction; Wnt signaling pathway; Organoid; Transforming growth factor beta; Gene; Transition (genetics); Genetics","score_opus":0.01786123324796301,"score_gpt":0.20894578804752884,"score_spread":0.19108455479956582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3080361388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9836759,0.0077924216,0.006633569,0.0008655901,0.000034459044,0.00029136715,0.00048569278,0.000024499803,0.00019648651],"genre_scores_gemma":[0.9972931,0.00078708614,0.0007519378,0.0007274509,0.0001481459,0.000008229935,0.00016673538,0.000019259702,0.000098065764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916536,0.000014622336,0.00020964,0.00027719166,0.00018232715,0.00015083994],"domain_scores_gemma":[0.9990891,0.000020934449,0.00006451163,0.00011347032,0.00005306104,0.00065891835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006533823,0.00013659922,0.0002302905,0.000041084324,0.000060330054,0.000017249968,0.000026593681,0.000043934804,0.0001831987],"category_scores_gemma":[0.000017457027,0.00012190407,0.00007433807,0.000119156175,0.000049406965,0.00007071736,0.0000148962445,0.000050476363,0.000003402327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007944367,0.00013870675,0.0009579202,0.0004934101,0.000016116182,0.00001365676,0.00047059575,0.000022038836,0.99040055,0.000045863024,0.0004684228,0.0061782515],"study_design_scores_gemma":[0.006134078,0.0004397399,0.014858438,0.00012662327,0.0005974957,0.000011826733,0.0004585893,0.0019039438,0.95830077,0.00011894794,0.016687978,0.00036159862],"about_ca_topic_score_codex":0.00002262119,"about_ca_topic_score_gemma":3.9559217e-7,"teacher_disagreement_score":0.03209984,"about_ca_system_score_codex":0.0000141150595,"about_ca_system_score_gemma":0.000092467795,"threshold_uncertainty_score":0.49711037},"labels":[],"label_agreement":null},{"id":"W3085393855","doi":"10.1038/s41419-020-02964-2","title":"Activation of Wnt signaling by amniotic fluid stem cell-derived extracellular vesicles attenuates intestinal injury in experimental necrotizing enterocolitis","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Burman University; Heart and Stroke Foundation; Hospital for Sick Children","funders":"Medical Research Council; National Institute for Health and Care Research; Canadian Institutes of Health Research; Hospital for Sick Children; Government of Canada; Thrasher Research Fund","keywords":"Wnt signaling pathway; Necrotizing enterocolitis; Stem cell; Regeneration (biology); Intestinal epithelium; Cell biology; Immunology; Biology; Inflammation; Cancer research; Amniotic fluid; Medicine; Signal transduction; Internal medicine; Pathology; Epithelium; Fetus; Pregnancy","score_opus":0.021884855428040497,"score_gpt":0.2583628175764252,"score_spread":0.2364779621483847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3085393855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99663866,0.002202625,0.000092922,0.0004884165,0.000044177992,0.00042240298,0.000026556461,0.000028410697,0.00005581493],"genre_scores_gemma":[0.9990121,0.000028726246,0.00016137071,0.0006492623,0.000043703443,0.000024080862,0.00005580139,0.000017723301,0.00000720332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989201,0.00008994299,0.00034654484,0.000269294,0.00012727248,0.00024688325],"domain_scores_gemma":[0.999386,0.000053891392,0.000099167744,0.000073025396,0.000023918014,0.00036397134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000719585,0.00014268499,0.00019968441,0.00008369275,0.00006719033,0.000032253727,0.000054777367,0.000041893032,0.000039346505],"category_scores_gemma":[0.000019239948,0.00015856294,0.000043707438,0.00011000966,0.000034892753,0.00015418771,0.000026614058,0.0001193107,0.0000038397084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011039757,0.00032577722,0.029888947,0.0005614627,0.0000011810605,0.000023691637,0.0017971853,0.000024119267,0.96572995,0.00002289058,0.00016047592,0.00036035036],"study_design_scores_gemma":[0.0016352899,0.0002325492,0.006055991,0.00029182236,0.000011289257,7.4952914e-7,0.0019622834,0.0034409019,0.9860848,0.000049901635,0.00007144631,0.00016294961],"about_ca_topic_score_codex":0.00007916061,"about_ca_topic_score_gemma":6.318166e-7,"teacher_disagreement_score":0.023832954,"about_ca_system_score_codex":0.00006498586,"about_ca_system_score_gemma":0.000035624285,"threshold_uncertainty_score":0.64660084},"labels":[],"label_agreement":null},{"id":"W3087247858","doi":"10.1038/s41419-020-02944-6","title":"BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; Sunnybrook Hospital","funders":"Vlaamse regering; Kom op tegen Kanker; Associazione Italiana per la Ricerca sul Cancro; Canadian Institutes of Health Research; KU Leuven; Fonds Wetenschappelijk Onderzoek; Bijzonder Onderzoeksfonds UGent; Government of Canada","keywords":"Venetoclax; Apoptosis; Cancer research; Programmed cell death; Cancer; Protein kinase B; Chronic lymphocytic leukemia; MCL1; Cell culture; Cancer cell; Biology; PI3K/AKT/mTOR pathway; Cell; Bcl-2-associated X protein; Downregulation and upregulation; Chemistry; Leukemia; Immunology; Caspase 3; Biochemistry; Genetics","score_opus":0.01403056165620724,"score_gpt":0.24049477616406298,"score_spread":0.22646421450785573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3087247858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872417,0.007979977,0.0031648206,0.00010069069,0.000044124965,0.00029161666,0.00025994447,0.000005574406,0.00091154565],"genre_scores_gemma":[0.996748,0.002160898,0.0005310095,0.0001843649,0.000051854382,0.000028731563,0.00015073089,0.000017558366,0.00012687709],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895185,0.00005521809,0.00028418005,0.00036953713,0.00015516492,0.00018402304],"domain_scores_gemma":[0.9992907,0.00000977004,0.00015724727,0.0001600138,0.00006436084,0.00031792096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007921034,0.00017134204,0.00023303505,0.000032081363,0.00004000106,0.000013022488,0.000108879256,0.0001281728,0.000022439084],"category_scores_gemma":[0.000012218361,0.00015474384,0.000098580495,0.0000988609,0.000058792783,0.000013261347,0.00009775809,0.000065362154,4.9371346e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007365116,0.0003234058,0.0029108112,0.00048051565,0.00003623242,0.0000069112743,0.0008769607,0.0018074206,0.99105275,0.00052127166,0.000104612875,0.001142571],"study_design_scores_gemma":[0.004073632,0.0005278994,0.0059884386,0.00006892394,0.00016749428,8.0143013e-7,0.0012298011,0.0071598412,0.9736607,0.005638677,0.0009377799,0.00054599706],"about_ca_topic_score_codex":0.00029306815,"about_ca_topic_score_gemma":0.00002615841,"teacher_disagreement_score":0.017392062,"about_ca_system_score_codex":0.000012918759,"about_ca_system_score_gemma":0.00019293278,"threshold_uncertainty_score":0.6310271},"labels":[],"label_agreement":null},{"id":"W3088031542","doi":"10.1038/s41419-020-02983-z","title":"pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; National Natural Science Foundation of China; CHDI Foundation; Agency for Science, Technology and Research; Ministry of Education - Singapore","keywords":"Huntingtin; Neuroprotection; Biology; Neurodegeneration; Cell biology; Context (archaeology); Induced pluripotent stem cell; Mitochondrion; Phosphorylation; Genetics; Mutant; Neuroscience; Gene; Embryonic stem cell","score_opus":0.04045175648992289,"score_gpt":0.24514803658658352,"score_spread":0.20469628009666063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3088031542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982014,0.0001305663,0.0005310256,0.00039450979,0.000076602475,0.00037374877,0.00004642904,0.000061728926,0.00018401517],"genre_scores_gemma":[0.9972784,0.00004480978,0.00023486381,0.002239238,0.00010175072,0.00002792058,0.000006317748,0.000023676763,0.000043020158],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99863774,0.0001398391,0.00015951713,0.0006761245,0.00015553492,0.00023125876],"domain_scores_gemma":[0.99893785,0.00004081588,0.000047140973,0.00015587642,0.00002348119,0.00079486385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000021938959,0.00018078156,0.00014003277,0.000053218824,0.00012723007,0.00012600447,0.000099741614,0.000030431333,0.000015415648],"category_scores_gemma":[0.00048340872,0.00017952193,0.0000314969,0.00011018016,0.000086695254,0.0001794165,0.000073830044,0.000105257735,0.000007438433],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004904478,0.00014588502,0.011195013,0.0000823364,7.509129e-7,0.000034101453,0.00028190808,0.010142338,0.97631985,0.00036590153,0.000052137195,0.00088932284],"study_design_scores_gemma":[0.0017490226,0.00022075184,0.025087608,0.000011694593,0.000046631336,9.903864e-7,0.000062185245,0.6041088,0.36541846,0.00284389,0.00005887048,0.00039108042],"about_ca_topic_score_codex":0.000011196809,"about_ca_topic_score_gemma":0.0000028835898,"teacher_disagreement_score":0.6109014,"about_ca_system_score_codex":0.0000056111085,"about_ca_system_score_gemma":0.0000748472,"threshold_uncertainty_score":0.7320692},"labels":[],"label_agreement":null},{"id":"W3092492112","doi":"10.1038/s41419-020-03062-z","title":"Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy","year":2020,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":141,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Ontario Ministry of Research and Innovation; Canadian Institutes of Health Research","keywords":"Biology; Mitochondrial matrix; Proteases; Protease; Mitochondrion; Serine protease; Cell biology; Cancer cell; Function (biology); Biochemistry; Cancer; Enzyme; Genetics; Cytosol","score_opus":0.048029583642661265,"score_gpt":0.34232003941864575,"score_spread":0.2942904557759845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092492112","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015309785,0.9955065,0.00068560307,0.00006485445,0.00014151451,0.0014526978,0.00056518737,0.000013168276,0.000039457424],"genre_scores_gemma":[0.00041117528,0.9948365,0.00018984696,0.00013272009,0.0015523524,0.00094111427,0.0015394902,0.000037032984,0.00035973865],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99877936,0.00007789836,0.00019332232,0.00060176325,0.00008147619,0.0002662033],"domain_scores_gemma":[0.9991301,0.000021555255,0.00007897515,0.00017492242,0.000038036902,0.0005564263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004773485,0.000295945,0.00045092558,0.000027358094,0.00012601216,0.00004334312,0.00009585975,0.00019427048,0.00006572692],"category_scores_gemma":[0.00007945088,0.000212644,0.00023090909,0.000043326178,0.00005497234,0.0000033099382,0.00010800432,0.000115714785,0.0000047315125],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015224798,0.00012405899,0.00022569102,0.006097076,0.0001932187,0.000028835799,0.0000046534687,9.3984073e-7,0.0026304794,0.000028635584,0.0038015107,0.98534244],"study_design_scores_gemma":[0.00067794934,0.00040023495,0.000013925368,0.00019240972,0.00017064565,8.401219e-7,0.000004055089,0.00002619142,0.00012298023,0.000093135044,0.9980306,0.000267044],"about_ca_topic_score_codex":0.0000054895436,"about_ca_topic_score_gemma":3.9093305e-7,"teacher_disagreement_score":0.9942291,"about_ca_system_score_codex":0.000008542202,"about_ca_system_score_gemma":0.00031205916,"threshold_uncertainty_score":0.8671371},"labels":[],"label_agreement":null},{"id":"W3093379611","doi":"10.1038/s41419-020-03063-y","title":"Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Associazione Italiana per la Ricerca sul Cancro; Consiglio Nazionale delle Ricerche; Università degli Studi di Padova; Ministero della Salute; Ministero dell’Istruzione, dell’Università e della Ricerca; National Science Council","keywords":"Neurodegeneration; Endoplasmic reticulum; Cell biology; Calcium; Calcium signaling; Unfolded protein response; Calcium-binding protein; SERCA; Chemistry; Biology; Internal medicine; Signal transduction; Medicine; Biochemistry; Disease","score_opus":0.011212447238482214,"score_gpt":0.21669422613992123,"score_spread":0.205481778901439,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3093379611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973935,0.0011260423,0.0003206146,0.00034140737,0.000050398477,0.00018682843,0.00052639964,0.000013930951,0.00004091324],"genre_scores_gemma":[0.9978004,0.00010569343,0.000068631496,0.0013765563,0.00013504617,0.000010371722,0.00030023648,0.000020755071,0.0001822876],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990283,0.00011320507,0.00016887148,0.00042321632,0.00011783743,0.00014855678],"domain_scores_gemma":[0.9989592,0.000010332215,0.00006459983,0.00016852787,0.00008580051,0.00071158144],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000037757767,0.00015315355,0.00014995785,0.000036237383,0.00008466728,0.000047550682,0.000062025676,0.000049239025,0.00001404153],"category_scores_gemma":[0.00015484169,0.00015047519,0.000047857113,0.00008971827,0.000042556614,0.00001082114,0.000062441715,0.000040168234,0.0000011779495],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007549651,0.00019658546,0.29519182,0.00008365248,0.00003102133,0.00001175157,0.00048655897,0.001110409,0.69946545,0.00007204499,0.0018602279,0.00073551666],"study_design_scores_gemma":[0.0011133018,0.0005386513,0.6539565,0.000013339529,0.00017156728,5.290232e-7,0.00005432435,0.0064557,0.3369249,0.000050837687,0.00040436737,0.00031597633],"about_ca_topic_score_codex":0.000019597312,"about_ca_topic_score_gemma":0.000004685851,"teacher_disagreement_score":0.36254054,"about_ca_system_score_codex":0.0000021401574,"about_ca_system_score_gemma":0.00005292015,"threshold_uncertainty_score":0.61362},"labels":[],"label_agreement":null},{"id":"W3098841897","doi":"10.1038/s41419-020-03159-5","title":"Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of British Columbia; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Killam Trusts; Dalhousie University; Strong; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Raloxifene; Hypoxia (environmental); Selective estrogen receptor modulator; Cancer research; Pharmacology; Chemistry; Estrogen receptor; Cell biology; Biology; Internal medicine; Medicine; Breast cancer; Cancer","score_opus":0.006310366836674712,"score_gpt":0.21987634575139373,"score_spread":0.213565978914719,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3098841897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960526,0.0027603891,0.0003464296,0.00018898977,0.000014107037,0.00036914018,0.00018951931,0.000010896144,0.00006790883],"genre_scores_gemma":[0.9991246,0.0002675271,0.000077244,0.00010756782,0.000081205726,0.000026514503,0.00006643228,0.000016587031,0.00023231305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892193,0.00006346993,0.00017007356,0.00038633682,0.0001378405,0.00032033242],"domain_scores_gemma":[0.99904454,0.000013694584,0.000036813995,0.000119384524,0.000026821317,0.0007587379],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006198902,0.00016323845,0.00014003427,0.00003708449,0.00010696213,0.000041242,0.00008702767,0.00006351543,0.00001128165],"category_scores_gemma":[0.000033336666,0.00015415416,0.000058186306,0.000056857676,0.000042538097,0.000013131171,0.000047588255,0.000082453866,0.000002267952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010872564,0.00015917307,0.15250687,0.0002926537,0.000011745749,0.000045365563,0.000064737746,0.00014078194,0.8454794,0.000007866599,0.000058015496,0.00014608497],"study_design_scores_gemma":[0.009176983,0.00062432373,0.45114988,0.0000664785,0.00007446973,0.0000043960445,0.00007924105,0.010948784,0.5269702,0.00021058154,0.00015969248,0.0005349431],"about_ca_topic_score_codex":0.000019459889,"about_ca_topic_score_gemma":0.000011267568,"teacher_disagreement_score":0.31850922,"about_ca_system_score_codex":0.000006422416,"about_ca_system_score_gemma":0.000085263964,"threshold_uncertainty_score":0.6286224},"labels":[],"label_agreement":null},{"id":"W3102888846","doi":"10.1038/s41419-020-03168-4","title":"Stroma secreted IL6 selects for “stem-like” population and alters pancreatic tumor microenvironment by reprogramming metabolic pathways","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Welichem Biotech (Canada)","funders":"Office of Extramural Research, National Institutes of Health; Florida Department of Health; Sylvester Comprehensive Cancer Center, University of Miami Health Systems; University of Miami; Pancreatic Cancer Action Network; National Cancer Institute; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Tumor microenvironment; Pancreatic cancer; Stromal cell; Stroma; Cancer research; Biology; Population; Pancreatic tumor; Cytokine; Reprogramming; Immune system; Cancer; Immunology; Medicine; Cell; Immunohistochemistry","score_opus":0.02470500121604689,"score_gpt":0.2634303398009052,"score_spread":0.2387253385848583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3102888846","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98907804,0.00825684,0.0007189914,0.00054451555,0.000018300912,0.0011706381,0.000083247374,0.000043076783,0.00008636267],"genre_scores_gemma":[0.99574536,0.00051428366,0.001564201,0.0013550154,0.000077197714,0.00015648582,0.00030347626,0.000024909798,0.00025904883],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99876785,0.000058822745,0.0002250183,0.00043523527,0.0001669516,0.00034613002],"domain_scores_gemma":[0.99839383,0.0000917463,0.00007232516,0.00016709216,0.000023417108,0.001251563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011577015,0.000174853,0.00041306467,0.000038626586,0.00014106966,0.000030256197,0.000040743198,0.000046420362,0.000024476945],"category_scores_gemma":[0.000116870855,0.00015021152,0.000063847845,0.00007101521,0.000063543295,0.00005445948,0.000039657112,0.00009345808,0.0000051265283],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014057427,0.00017565118,0.97262776,0.000984417,0.00009718835,0.00009955091,0.00032511077,0.0000011279863,0.019412275,0.00007880447,0.0012543707,0.0035380204],"study_design_scores_gemma":[0.011135752,0.002143657,0.94419694,0.00015883069,0.0032005433,0.00003896077,0.0007039814,0.02501505,0.0022708399,0.0003599322,0.010212812,0.0005627118],"about_ca_topic_score_codex":0.000039628798,"about_ca_topic_score_gemma":6.6130207e-7,"teacher_disagreement_score":0.02843081,"about_ca_system_score_codex":0.000030564468,"about_ca_system_score_gemma":0.00009304238,"threshold_uncertainty_score":0.6125448},"labels":[],"label_agreement":null},{"id":"W3111545591","doi":"10.1038/s41419-020-03241-y","title":"Autocrine IL-6/STAT3 signaling aids development of acquired drug resistance in Group 3 medulloblastoma","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; BC Children's Hospital; University of British Columbia","funders":"Mitacs; BC Children's Hospital; Children's Hospital Foundation","keywords":"Autocrine signalling; Medulloblastoma; Paracrine signalling; STAT3; Cancer research; Cytokine; Biology; Vincristine; SOCS3; Drug resistance; Secretion; Cell culture; Pharmacology; Signal transduction; Medicine; Immunology; Internal medicine; Cell biology; Chemotherapy; Endocrinology; Receptor","score_opus":0.019502378054437997,"score_gpt":0.24931137959337818,"score_spread":0.22980900153894018,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111545591","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99587804,0.001128786,0.0010117365,0.0006244179,0.0000470825,0.00023296283,0.000028383205,0.00004216733,0.0010064278],"genre_scores_gemma":[0.99375904,0.000022634036,0.0051690126,0.00059939595,0.000062829575,0.000022371707,0.00005245882,0.000016599819,0.00029566916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899805,0.000023071192,0.0003442858,0.000267215,0.00017874397,0.00018864512],"domain_scores_gemma":[0.99908257,0.00004323276,0.00007246224,0.00012431026,0.000051323506,0.00062610384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007536858,0.00013757838,0.0002401433,0.00008136798,0.000057708457,0.000012590588,0.000054106764,0.00002132369,0.00015849288],"category_scores_gemma":[0.00011505024,0.00012549655,0.000065506705,0.00016868912,0.00003337866,0.00006470411,0.000041986128,0.00006185611,0.000009850149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007974257,0.0015857973,0.061096054,0.003723129,0.00011026669,0.000886672,0.0102661075,0.000092078444,0.90269417,0.0018293462,0.004848087,0.0048940578],"study_design_scores_gemma":[0.022105865,0.0012091488,0.19944832,0.003752761,0.0008710176,0.00001553817,0.003920064,0.006786171,0.5877612,0.0021763186,0.17005318,0.0019004014],"about_ca_topic_score_codex":0.000008859317,"about_ca_topic_score_gemma":0.000011803854,"teacher_disagreement_score":0.31493294,"about_ca_system_score_codex":0.00003307133,"about_ca_system_score_gemma":0.0002286415,"threshold_uncertainty_score":0.51176006},"labels":[],"label_agreement":null},{"id":"W3120459943","doi":"10.1038/s41419-020-03308-w","title":"A triple-drug nanotherapy to target breast cancer cells, cancer stem cells, and tumor vasculature","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; Health Canada; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Huntsman Cancer Institute; Canadian Institutes of Health Research; Cancer Research Society; University of Ottawa","keywords":"Triple-negative breast cancer; Verteporfin; Cancer research; Cancer stem cell; Paclitaxel; Breast cancer; Medicine; Cancer; Cancer cell; Stem cell; Taxane; Internal medicine; Macular degeneration; Biology; Choroidal neovascularization; Cell biology","score_opus":0.005970357087394155,"score_gpt":0.21875214886427696,"score_spread":0.2127817917768828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120459943","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9430282,0.05460976,0.0001157239,0.0004303114,0.00028216996,0.00020468392,0.0011852955,0.000018973065,0.0001248772],"genre_scores_gemma":[0.98601955,0.0041008666,0.00026371845,0.0029413926,0.000375765,0.000081286395,0.00007385464,0.000042371794,0.006101194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987296,0.00006254876,0.00014997706,0.00060549524,0.00012945644,0.00032293514],"domain_scores_gemma":[0.99871135,0.0000065840077,0.000045648092,0.0003090187,0.00010029353,0.0008271032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000066746936,0.0002387978,0.000198832,0.000029833178,0.00013663016,0.0000707733,0.000092492926,0.00007798983,0.0001078431],"category_scores_gemma":[0.0000048190054,0.00021461995,0.0001030701,0.00009205372,0.00004395104,0.0000053653766,0.00007325408,0.00008832329,0.0000053866233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029989332,0.00012277561,0.004579773,0.00017134337,0.000048344697,0.00013203954,0.00013127438,0.00019033354,0.98888475,0.000011960382,0.0035207227,0.0019067626],"study_design_scores_gemma":[0.0016998472,0.000054400305,0.0032473088,0.00008583407,0.00012180073,0.000018829978,0.00012090893,0.00018238217,0.87160754,0.0000570555,0.12224215,0.0005619171],"about_ca_topic_score_codex":0.000111248984,"about_ca_topic_score_gemma":0.0000405497,"teacher_disagreement_score":0.118721426,"about_ca_system_score_codex":0.000014452081,"about_ca_system_score_gemma":0.00040209503,"threshold_uncertainty_score":0.8751948},"labels":[],"label_agreement":null},{"id":"W3122442658","doi":"10.1038/s41419-020-03361-5","title":"Deubiquitylating enzymes in neuronal health and disease","year":2021,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Koret Foundation","keywords":"Proteostasis; Disease; Biology; Neuroscience; Proteome; Function (biology); Ubiquitin; Computational biology; Bioinformatics; Cell biology; Medicine; Genetics; Gene; Pathology","score_opus":0.03543627314412833,"score_gpt":0.30701255972533625,"score_spread":0.2715762865812079,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122442658","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018612008,0.99695736,0.000018848687,0.00006147089,0.00006197436,0.00047385096,0.0002720698,0.000010305322,0.00028291292],"genre_scores_gemma":[0.001843093,0.9952145,0.000111818656,0.0008022273,0.00021183038,0.0000950625,0.0013181195,0.00004178974,0.00036156067],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982502,0.00025572392,0.00033791282,0.0006915735,0.0001097953,0.00035479033],"domain_scores_gemma":[0.99761003,0.00003355538,0.00013885673,0.00031959976,0.000020886975,0.00187705],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014610264,0.00035078725,0.0006023851,0.00006733919,0.00010668618,0.00006845486,0.00011011848,0.00012488039,0.000018109977],"category_scores_gemma":[0.00030344952,0.0003242421,0.0001831127,0.000077469915,0.00005420745,0.0000040514115,0.00026590392,0.00018412888,0.000003206019],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012076224,0.00030781145,0.0037442013,0.048133355,0.000049848088,0.00033277948,0.000059357568,0.0000015166263,0.00002229579,0.0011872994,0.0021984084,0.94384235],"study_design_scores_gemma":[0.00042831438,0.00010424988,0.00022197583,0.002988486,0.00015733828,0.00001034315,0.000019286968,0.000017968325,0.000019817111,0.00016993376,0.9953542,0.00050809997],"about_ca_topic_score_codex":0.000008008663,"about_ca_topic_score_gemma":0.0000032570636,"teacher_disagreement_score":0.9931558,"about_ca_system_score_codex":0.000014911728,"about_ca_system_score_gemma":0.0017249087,"threshold_uncertainty_score":0.99992096},"labels":[],"label_agreement":null},{"id":"W3126781502","doi":"10.1038/s41419-021-03417-0","title":"HDAC4 promotes nasopharyngeal carcinoma progression and serves as a therapeutic target","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Natural Science Foundation of China; National Science Foundation","keywords":"HDAC4; Nasopharyngeal carcinoma; Cancer research; Gene knockdown; Epithelial–mesenchymal transition; Biology; Tumor progression; Histone deacetylase; Metastasis; Downregulation and upregulation; HDAC1; Histone; Cell culture; Cancer; Medicine; Internal medicine; Radiation therapy","score_opus":0.010888078565585322,"score_gpt":0.27406934302933333,"score_spread":0.263181264463748,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126781502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9590125,0.039266545,0.000015845446,0.0002568144,0.00003632177,0.00019330748,0.000027671782,0.000010722684,0.0011802443],"genre_scores_gemma":[0.9967758,0.000314113,0.00022549568,0.0002489481,0.00011791343,0.000035765654,0.00020946564,0.00001966762,0.0020528368],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903333,0.00008228252,0.00009907906,0.0004103082,0.00013804957,0.00023692835],"domain_scores_gemma":[0.99911416,0.0000100773805,0.00002438084,0.00023623963,0.00007145735,0.0005436847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006740419,0.00013738843,0.00010488833,0.000024463387,0.00013341075,0.00005648202,0.0000627293,0.00007270793,0.000045436267],"category_scores_gemma":[0.000078670906,0.000121302946,0.000047573812,0.000051027913,0.000085807056,0.000005964493,0.00014794953,0.00007384911,0.000009392478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043893224,0.00033182776,0.06561212,0.0003569132,0.000024972982,0.00051884423,0.000116711606,9.834165e-7,0.9276958,0.00009694125,0.0011858495,0.0036201067],"study_design_scores_gemma":[0.0012121359,0.0003414357,0.026576262,0.00003353717,0.000041041432,0.000043374355,0.0000674955,0.00019301796,0.95939124,0.00055444124,0.011259388,0.0002866345],"about_ca_topic_score_codex":0.0000074515347,"about_ca_topic_score_gemma":0.0000023916734,"teacher_disagreement_score":0.03903586,"about_ca_system_score_codex":0.000007039328,"about_ca_system_score_gemma":0.00030786585,"threshold_uncertainty_score":0.49465907},"labels":[],"label_agreement":null},{"id":"W3131502825","doi":"10.1038/s41419-021-03491-4","title":"Distinct Ring1b complexes defined by DEAD-box helicases and EMT transcription factors synergistically enhance E-cadherin silencing in breast cancer","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Natural Science Foundation of China; University of Bristol; Northeast Normal University","keywords":"Epigenetics; Epithelial–mesenchymal transition; Cancer research; Transcription factor; CDH1; Gene silencing; Cadherin; Biology; Breast cancer; Metastasis; Cell biology; Cancer; Bioinformatics; Cell; Genetics; Gene","score_opus":0.011002778088118628,"score_gpt":0.2508606986143735,"score_spread":0.23985792052625488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3131502825","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9807558,0.016795952,0.0017440579,0.00011540527,0.00004328679,0.00007737913,0.00033884114,0.000007541729,0.000121755205],"genre_scores_gemma":[0.99627805,0.0029334743,0.00015977514,0.00007933635,0.0000464476,0.000017318245,0.0003158706,0.000014008055,0.0001557053],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991586,0.00004702624,0.00016038686,0.00036704558,0.00007851681,0.00018837604],"domain_scores_gemma":[0.9994658,0.00002547881,0.00003593613,0.00013124822,0.000045496334,0.0002960012],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004478965,0.00014693497,0.00012676702,0.000019164601,0.0000758502,0.00004304848,0.00003986615,0.00006282875,0.000031390075],"category_scores_gemma":[0.00006566389,0.00014230906,0.000037413254,0.000049976145,0.000048754,0.0000057920424,0.00003670453,0.000049983653,6.015866e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079269244,0.000096615346,0.14150083,0.000097106116,0.0000062667,0.000012218229,0.000027616456,0.000031075917,0.85692036,0.000033670727,0.000037971597,0.0011569883],"study_design_scores_gemma":[0.00055302936,0.000053009546,0.51652914,0.00004923542,0.000055082106,0.0000018826084,0.000067173096,0.00036249525,0.4808411,0.0002656017,0.00093534036,0.00028691912],"about_ca_topic_score_codex":0.00017514155,"about_ca_topic_score_gemma":0.00013763978,"teacher_disagreement_score":0.3760793,"about_ca_system_score_codex":0.00001136799,"about_ca_system_score_gemma":0.00007648753,"threshold_uncertainty_score":0.58031946},"labels":[],"label_agreement":null},{"id":"W3135162074","doi":"10.1038/s41419-021-03526-w","title":"Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Office of Extramural Research, National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; U.S. Department of Health and Human Services; National Institutes of Health; Government of Canada; Cystic Fibrosis Foundation Therapeutics; Cystic Fibrosis Foundation","keywords":"Pseudomonas aeruginosa; Inflammasome; Cystic fibrosis; Microbiology; Virulence; Biology; Inflammation; Immunology; Chronic infection; Immune system; Cytokine; Programmed cell death; Bacteria; Apoptosis; Gene","score_opus":0.004272756269300803,"score_gpt":0.20172432948444052,"score_spread":0.19745157321513973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135162074","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99664366,0.0027972625,5.8568287e-7,0.000089216104,0.000048179605,0.00022660896,0.00017493848,0.0000044767467,0.000015098038],"genre_scores_gemma":[0.99876255,0.00016248068,0.00004506527,0.00014641219,0.0000567908,0.000017311246,0.00077580276,0.000014602474,0.000018976434],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983776,0.0003932656,0.00037088973,0.00045667985,0.0000798965,0.00032162134],"domain_scores_gemma":[0.9992829,0.00008218665,0.00006704452,0.00029860015,0.000026598393,0.00024264425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002634893,0.0001816106,0.0001595258,0.00007013943,0.00004165164,0.00006297012,0.00009053657,0.00011725673,0.000006895515],"category_scores_gemma":[0.00023784892,0.00016090095,0.00004020257,0.00011750521,0.000041363895,0.00001683198,0.00011791294,0.0001215712,0.0000017735733],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005074564,0.00021947542,0.30460846,0.000024095812,0.0000027533927,0.0001232297,0.00014489336,0.00013968081,0.6892903,0.0000012713042,0.000021317097,0.0003499615],"study_design_scores_gemma":[0.0051232106,0.00023426618,0.9045055,0.00015228045,0.0000117153895,8.970716e-7,0.00013778268,0.0004962824,0.08866123,0.000051583203,0.0003290915,0.00029616005],"about_ca_topic_score_codex":0.00036927682,"about_ca_topic_score_gemma":0.00056264596,"teacher_disagreement_score":0.6006291,"about_ca_system_score_codex":0.00006816125,"about_ca_system_score_gemma":0.00028124006,"threshold_uncertainty_score":0.656135},"labels":[],"label_agreement":null},{"id":"W3135259094","doi":"10.1038/s41419-021-03506-0","title":"Caspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Jewish General Hospital","funders":"College of Engineering, Michigan State University; Université Laval; Jewish General Hospital; Michigan State University; Canadian Institutes of Health Research; Alzheimer Society; Fondation de l'Hôpital général juif; Northwestern University","keywords":"Neurodegeneration; Hippocampal formation; Tauopathy; Hyperphosphorylation; Tau protein; Cognitive decline; Hippocampus; Neuroscience; Neuropathology; Alzheimer's disease; Biology; Pathology; Medicine; Phosphorylation; Cell biology; Dementia; Disease","score_opus":0.020570152010384566,"score_gpt":0.2682724857910879,"score_spread":0.24770233378070336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135259094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98655266,0.011188538,0.00021360848,0.0008774407,0.000037861617,0.00064800645,0.0001127414,0.00003455912,0.00033459833],"genre_scores_gemma":[0.99783975,0.0004844874,0.0002109937,0.00049438473,0.00013419107,0.00007216786,0.00058478833,0.000021420366,0.00015779195],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99875623,0.00007550452,0.00020098471,0.00045685848,0.000266106,0.00024434098],"domain_scores_gemma":[0.9977882,0.000078969526,0.000049378432,0.0001588691,0.00041532321,0.00150925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000066732086,0.00018938872,0.00018769944,0.00009282951,0.00026464206,0.00015090161,0.000020512363,0.0000578578,0.00005156335],"category_scores_gemma":[0.00049889757,0.0001791594,0.000034150755,0.0001782903,0.00006257189,0.00025237194,0.000056712124,0.00008269802,0.000027108024],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045186016,0.0011648455,0.8930362,0.00082024786,0.0013740903,0.0029388124,0.0017490634,0.00003422559,0.012709971,0.0014591431,0.001901786,0.07829305],"study_design_scores_gemma":[0.005627992,0.0002835208,0.96035695,0.00016154208,0.001366382,0.000052393196,0.00051659666,0.0009852814,0.029241504,0.0008590797,0.00019688405,0.0003518635],"about_ca_topic_score_codex":0.000038586808,"about_ca_topic_score_gemma":0.000014894828,"teacher_disagreement_score":0.07794119,"about_ca_system_score_codex":0.000025138106,"about_ca_system_score_gemma":0.0004483053,"threshold_uncertainty_score":0.7305908},"labels":[],"label_agreement":null},{"id":"W3137253956","doi":"10.1038/s41419-021-03528-8","title":"Immune complex-induced apoptosis and concurrent immune complex clearance are anti-inflammatory neutrophil functions","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Foundation; Medical Research Council; Versus Arthritis; Arthritis Research UK; University of Southampton; Research Councils UK; Université Laval","keywords":"Phagocytosis; Inflammation; Immune system; Immunology; Apoptosis; Efferocytosis; Pinocytosis; Biology; Neutrophil extracellular traps; Cell biology; Granulocyte; Macrophage; Receptor; Endocytosis; In vitro; Biochemistry","score_opus":0.027545202096489627,"score_gpt":0.23476360722156764,"score_spread":0.207218405125078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3137253956","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981343,0.016132092,0.00021150737,0.00060202094,0.00058582897,0.00029741268,0.00027053486,0.00009854336,0.00045908595],"genre_scores_gemma":[0.9965839,0.0010550568,0.000044940523,0.0005903821,0.000064860986,0.000027295362,0.00059762405,0.000033669916,0.001002286],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99819237,0.00024318876,0.00038854615,0.00063274824,0.00006059127,0.00048258016],"domain_scores_gemma":[0.99889356,0.00007238402,0.00016358431,0.0004609172,0.00014647881,0.00026308218],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000087616856,0.00035926214,0.0005169768,0.00008948609,0.00063765276,0.00006543044,0.00014301858,0.00013750652,0.00067248364],"category_scores_gemma":[0.000042007727,0.00034326446,0.00015620921,0.00013939157,0.00022841722,0.00012791947,0.00023569583,0.00030328735,0.00024911464],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020022957,0.00024546258,0.002229555,0.00014683795,0.00010080707,0.00007915561,0.000078107325,0.0000024130215,0.992321,0.0014767072,0.0007784941,0.0023412262],"study_design_scores_gemma":[0.0055437796,0.00021554154,0.5285195,0.00014577381,0.00040044863,0.00005938196,0.00096832996,0.000052540337,0.43916333,0.00044088718,0.023642018,0.00084849575],"about_ca_topic_score_codex":0.000023481345,"about_ca_topic_score_gemma":0.0000029784362,"teacher_disagreement_score":0.5531577,"about_ca_system_score_codex":0.000025286163,"about_ca_system_score_gemma":0.000119452045,"threshold_uncertainty_score":0.99990195},"labels":[],"label_agreement":null},{"id":"W3137370550","doi":"10.1038/s41419-021-03513-1","title":"Inhibition of HECT E3 ligases as potential therapy for COVID-19","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; Université de Paris; Assistance publique-Hôpitaux de Paris; Institut National de la Santé et de la Recherche Médicale; Université Claude Bernard Lyon 1; NHLBI Division of Intramural Research; Universität Basel; Fondation pour la Recherche Médicale; St. Giles Foundation; Mercatus Center, George Mason University; Centre National de la Recherche Scientifique; George Mason University; Institut de Médecine et d'Epidémiologie Appliquée; Yale University; National Center for Advancing Translational Sciences; National Human Genome Research Institute; Agence Nationale de la Recherche; Georgia Clinical and Translational Science Alliance; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute","keywords":"NEDD4; Ubiquitin ligase; Ubiquitin; Biology; VP40; Cullin; Genetics; Virology; Gene; RNA","score_opus":0.0158911058375673,"score_gpt":0.2706394430630233,"score_spread":0.254748337225456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3137370550","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9651443,0.03283834,0.00051401113,0.0003711018,0.00018489515,0.00018378253,0.00017109924,0.000022708513,0.0005697904],"genre_scores_gemma":[0.9916955,0.00115916,0.000018631199,0.0016937054,0.000019188825,0.000023398561,0.0002938485,0.000007724985,0.0050888113],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99942744,0.00010045403,0.00013307239,0.00017322898,0.000016568189,0.00014923427],"domain_scores_gemma":[0.999575,0.000096228214,0.000043997872,0.00013073308,0.000058365098,0.00009568079],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005810581,0.000092086826,0.00013477981,0.000042728454,0.000116223724,0.000011701516,0.000035977944,0.00006788005,0.0006275478],"category_scores_gemma":[0.00024416577,0.00007986199,0.00011154566,0.000030540945,0.00008110613,0.00003572412,0.00002772368,0.000045173798,0.00003243808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005869349,0.00035271634,0.00054798415,0.000116954885,0.00004729274,0.00004686265,0.00014521151,0.0000027547205,0.98510885,0.0009454958,0.0046632434,0.0021533086],"study_design_scores_gemma":[0.0035208622,0.0003892396,0.0019232244,0.000018306608,0.0000577125,0.000029085366,0.0002690414,0.000004208466,0.95413744,0.0015200034,0.038005076,0.00012576953],"about_ca_topic_score_codex":0.00002700293,"about_ca_topic_score_gemma":0.000001008318,"teacher_disagreement_score":0.033341832,"about_ca_system_score_codex":0.0000096792355,"about_ca_system_score_gemma":0.00036359855,"threshold_uncertainty_score":0.6871208},"labels":[],"label_agreement":null},{"id":"W3139551563","doi":"10.1038/s41419-021-03614-x","title":"Regulated cell death pathways in doxorubicin-induced cardiotoxicity","year":2021,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":662,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Necroptosis; Cardiotoxicity; Doxorubicin; Pyroptosis; Autophagy; Programmed cell death; Apoptosis; Cancer research; Pharmacology; Medicine; Biology; Chemotherapy; Internal medicine; Biochemistry","score_opus":0.048844447493391764,"score_gpt":0.2938154110391936,"score_spread":0.24497096354580186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139551563","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07303252,0.9184693,0.000016850534,0.00002772689,0.0002011834,0.001779996,0.0001401752,0.00010132564,0.0062309066],"genre_scores_gemma":[0.12479732,0.87244236,0.000076248834,0.0003523257,0.0003714461,0.00013037813,0.000996668,0.00011022753,0.00072302873],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967838,0.00030029163,0.00076203805,0.0010907587,0.00045002135,0.0006130947],"domain_scores_gemma":[0.9971578,0.00012592695,0.00025230224,0.00093442196,0.00011306575,0.0014164574],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003040413,0.0007700684,0.0025956884,0.0003303038,0.00012091551,0.00007974217,0.00015336458,0.0006750379,0.00007672313],"category_scores_gemma":[0.00013371489,0.00068911834,0.0010930394,0.0005073989,0.000047172383,0.00009327798,0.00010225622,0.00077509874,0.00003227257],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043924808,0.0022997356,0.00126283,0.110892944,0.0006805789,0.008874115,0.0005421394,0.000010243824,0.019408872,0.0004863722,0.0015689988,0.8535339],"study_design_scores_gemma":[0.012271115,0.00056169607,0.0025733234,0.051046506,0.012756133,0.00037429668,0.00025321083,0.00018423336,0.03751916,0.0005756596,0.87782717,0.0040574973],"about_ca_topic_score_codex":0.000056670306,"about_ca_topic_score_gemma":0.0000033109006,"teacher_disagreement_score":0.8762582,"about_ca_system_score_codex":0.0003513847,"about_ca_system_score_gemma":0.0017879978,"threshold_uncertainty_score":0.999556},"labels":[],"label_agreement":null},{"id":"W3149633952","doi":"10.1038/s41419-021-03611-0","title":"Development of a bispecific immune engager using a recombinant malaria protein","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Gangstedfonden; Kirsten og Freddy Johansens Fond; Aase og Ejnar Danielsens Fond; Danmarks Grundforskningsfond; National Research Foundation; Svend Andersen Fonden; Kræftens Bekæmpelse","keywords":"Recombinant DNA; Malaria; Immune system; Virology; Biology; Immunology; Cancer research; Biochemistry; Gene","score_opus":0.018581065921423445,"score_gpt":0.24760878969667144,"score_spread":0.229027723775248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3149633952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931065,0.005409384,0.0006184425,0.000014032857,0.00011509956,0.00014384599,0.000014370754,0.000006565615,0.000571775],"genre_scores_gemma":[0.9952518,0.00013104889,0.0033908726,0.00005406868,0.00004657454,0.000025611294,0.00007896027,0.000014250528,0.0010068674],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923766,0.00005320338,0.00019653044,0.00027441588,0.00007971462,0.00015845012],"domain_scores_gemma":[0.9993478,0.0000033240635,0.00006607888,0.0002409623,0.0000725195,0.00026930767],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006748889,0.00011722917,0.000111906156,0.000024167444,0.00014261116,0.000022517266,0.00005259341,0.000054983022,0.00007654276],"category_scores_gemma":[0.000057986923,0.00010799065,0.000079584745,0.000055115994,0.000027590102,0.0000034185935,0.00012578907,0.00004639504,0.0000029578032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014138462,0.0002577828,0.0021231782,0.00016012267,0.000019710204,0.000027195427,0.000040117477,0.0000127559,0.99624544,0.00009990846,0.00019519877,0.0006771979],"study_design_scores_gemma":[0.0009623694,0.00006618962,0.01039401,0.00010845571,0.000043104024,0.000006022359,0.000108483895,0.000111966634,0.9757211,0.0002535933,0.011959288,0.000265373],"about_ca_topic_score_codex":0.0000048819834,"about_ca_topic_score_gemma":0.0000012285597,"teacher_disagreement_score":0.020524302,"about_ca_system_score_codex":0.000007505388,"about_ca_system_score_gemma":0.00037991826,"threshold_uncertainty_score":0.4403731},"labels":[],"label_agreement":null},{"id":"W3156557484","doi":"10.1038/s41419-021-03660-5","title":"Mitochondrial quality control protects photoreceptors against oxidative stress in the H2O2-induced models of retinal degeneration diseases","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; University of Ottawa","keywords":"Mitophagy; Cell biology; Mitochondrion; Neuroprotection; Oxidative stress; PINK1; Proteostasis; Retinal degeneration; Biology; Programmed cell death; Autophagy; Chemistry; Biochemistry; Pharmacology; Apoptosis; Retinal","score_opus":0.025819591037290167,"score_gpt":0.2834026461643412,"score_spread":0.25758305512705104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3156557484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99509406,0.0024637615,0.0003688571,0.00022785684,0.00009678601,0.00091043994,0.00030058384,0.00001832031,0.0005193386],"genre_scores_gemma":[0.9980619,0.00012424217,0.000069674985,0.0010205688,0.00020311633,0.0001535817,0.00028882214,0.000012763536,0.00006534804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985652,0.00033000548,0.0002880668,0.00031037958,0.00031403248,0.00019229764],"domain_scores_gemma":[0.99888146,0.00012256383,0.00010959513,0.00032157838,0.00016501115,0.00039981699],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095440315,0.00016689916,0.00027985242,0.00004764404,0.000082626204,0.000027655913,0.00007397704,0.000058382695,0.000049486836],"category_scores_gemma":[0.00029778507,0.00012035535,0.00012923483,0.00013258186,0.00006023722,0.00010509122,0.000017657168,0.00011655495,0.000001626739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02044562,0.009246577,0.12801932,0.0020675792,0.00029823664,0.0014222554,0.0042570676,0.0008573689,0.8216255,0.0058374084,0.0009376923,0.004985419],"study_design_scores_gemma":[0.02585714,0.00064578484,0.260454,0.0005788081,0.0009420818,0.0000048999923,0.0026250728,0.0106808515,0.68810946,0.009257188,0.00009688643,0.0007478061],"about_ca_topic_score_codex":0.000030009982,"about_ca_topic_score_gemma":0.0000071790428,"teacher_disagreement_score":0.13351597,"about_ca_system_score_codex":0.000026175136,"about_ca_system_score_gemma":0.00048593793,"threshold_uncertainty_score":0.49079487},"labels":[],"label_agreement":null},{"id":"W3167134283","doi":"10.1038/s41419-021-03851-0","title":"Neuroprotective effects of bone marrow Sca-1+ cells against age-related retinal degeneration in OPTN E50K mice","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Harbin Institute of Technology; Toronto General Hospital Research Institute, University Health Network; Heilongjiang Provincial Science and Technology Department; National Natural Science Foundation of China; Heilongjiang Postdoctoral Science Foundation","keywords":"Neuroprotection; Retinal degeneration; Bone marrow; Degeneration (medical); Retinal; Macular degeneration; Biology; Pathology; Cell biology; Neuroscience; Medicine; Retina; Ophthalmology; Biochemistry","score_opus":0.004416940578963519,"score_gpt":0.20330151400524063,"score_spread":0.1988845734262771,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3167134283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926726,0.0036136643,0.00005010305,0.00020206912,0.0001093421,0.00046732955,0.0000058754285,0.000015825663,0.0028631645],"genre_scores_gemma":[0.99794304,0.00038561775,0.00018707347,0.0003447557,0.000026515258,0.000019179497,0.00007242215,0.000017191507,0.0010042022],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990537,0.00009804098,0.00021770285,0.00029144244,0.00014835235,0.00019075844],"domain_scores_gemma":[0.9992849,0.000045729255,0.000063050116,0.00016387037,0.00007325147,0.00036920147],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006477635,0.00014191255,0.000239679,0.00008699416,0.000046984867,0.000012989789,0.000027554395,0.0000692726,0.00001812125],"category_scores_gemma":[0.00015581856,0.0001285005,0.00008758832,0.00019832623,0.00006479768,0.000038283753,0.000031941745,0.00015472663,0.000009238397],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000693883,0.0005442575,0.039153174,0.0015303624,0.0000128619695,0.0047496557,0.00022429042,0.00002744712,0.9518069,0.000050673643,0.00023706518,0.00096942973],"study_design_scores_gemma":[0.005790361,0.00034517574,0.60363543,0.0006120741,0.00033220777,0.000022685559,0.00017198807,0.0021543368,0.3861165,0.00037424857,0.00016440029,0.00028056928],"about_ca_topic_score_codex":0.000024156885,"about_ca_topic_score_gemma":0.0000051630464,"teacher_disagreement_score":0.5656904,"about_ca_system_score_codex":0.000018162795,"about_ca_system_score_gemma":0.00015556735,"threshold_uncertainty_score":0.5240098},"labels":[],"label_agreement":null},{"id":"W3167326398","doi":"10.1038/s41419-021-03871-w","title":"The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Russian Science Foundation; National Institutes of Health; Russian Foundation for Basic Research; York University","keywords":"Ubiquitin ligase; RNA-binding protein; RNA splicing; Small interfering RNA; Ubiquitin; Protein degradation; RNA; Biology; Cell biology; Chemistry; Biochemistry; Gene","score_opus":0.011713385984363195,"score_gpt":0.2506126548133672,"score_spread":0.238899268829004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3167326398","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940152,0.003933567,0.00027624078,0.00034747252,0.000019165062,0.000157016,0.00008189773,0.000003924331,0.0011654948],"genre_scores_gemma":[0.98736006,0.00030811317,0.0003507095,0.00021367124,0.00007554418,0.000026433816,0.00006222365,0.000011806637,0.011591423],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922025,0.000030509986,0.00012760302,0.00023910063,0.00012625163,0.00025625658],"domain_scores_gemma":[0.9992059,0.000013624555,0.00004201744,0.0002730437,0.00008181172,0.00038360103],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120689416,0.00009602145,0.00008576827,0.000015738915,0.00015836397,0.00004641261,0.00010653261,0.000043919736,0.000024143745],"category_scores_gemma":[0.0002197111,0.000072849645,0.000077051496,0.000056013323,0.000057256857,0.0000032774421,0.00013443167,0.00006241431,0.000004238208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014053927,0.000079984,0.0020126428,0.0000791598,0.000014286529,0.000024685078,0.000013961772,0.0000019732868,0.9960534,0.00014759437,0.00086326036,0.0005685234],"study_design_scores_gemma":[0.00058792357,0.00007245841,0.0009929953,0.000026599157,0.000013269606,0.0000021233898,0.00010192662,0.00019283345,0.99024093,0.00016663918,0.007497217,0.00010506031],"about_ca_topic_score_codex":0.000011469523,"about_ca_topic_score_gemma":0.0000028082707,"teacher_disagreement_score":0.010425928,"about_ca_system_score_codex":0.0000045911793,"about_ca_system_score_gemma":0.00025752748,"threshold_uncertainty_score":0.29707223},"labels":[],"label_agreement":null},{"id":"W3171901047","doi":"10.1038/s41419-021-03872-9","title":"Adipocyte death triggers a pro-inflammatory response and induces metabolic activation of resident macrophages","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Deutsche Forschungsgemeinschaft","keywords":"Adipocyte; Inflammation; Adipose tissue; Cell biology; Efferocytosis; Programmed cell death; Adipogenesis; Biology; Chemistry; Macrophage; Immunology; Endocrinology; Apoptosis; Biochemistry; In vitro","score_opus":0.017045207670176293,"score_gpt":0.2623942734790929,"score_spread":0.2453490658089166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3171901047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9692266,0.029251412,0.00003454561,0.00027181377,0.000059520193,0.000409187,0.000042599422,0.000043585227,0.00066075573],"genre_scores_gemma":[0.9940959,0.0027934846,0.00022336251,0.0002949289,0.00014401095,0.0000508531,0.00006171398,0.000023062948,0.002312673],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99863285,0.00016328452,0.00034087052,0.0003537314,0.0002864966,0.00022279819],"domain_scores_gemma":[0.9983597,0.00013077789,0.00014840512,0.00031746822,0.00020701408,0.00083665334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000227388,0.00020469596,0.00036264127,0.00017294164,0.00011043995,0.00003764249,0.000046459863,0.0000674117,0.000099704375],"category_scores_gemma":[0.00088148785,0.00017721677,0.00009989379,0.00016224734,0.00009383916,0.00020403818,0.00004577284,0.00008399066,0.000004386001],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.030876653,0.0012755452,0.50856656,0.0046315067,0.0005786688,0.0015798367,0.003271249,0.00003861866,0.41920516,0.005633786,0.0015751744,0.02276722],"study_design_scores_gemma":[0.0027039286,0.000061076935,0.8676961,0.00015203275,0.0007383952,0.000015361255,0.00028788837,0.00005292423,0.12082959,0.00044619842,0.006830194,0.0001862842],"about_ca_topic_score_codex":0.000022739192,"about_ca_topic_score_gemma":0.000001143699,"teacher_disagreement_score":0.35912955,"about_ca_system_score_codex":0.000017436903,"about_ca_system_score_gemma":0.0009084171,"threshold_uncertainty_score":0.72266906},"labels":[],"label_agreement":null},{"id":"W3172346058","doi":"10.1038/s41419-021-03904-4","title":"USP35, regulated by estrogen and AKT, promotes breast tumorigenesis by stabilizing and enhancing transcriptional activity of estrogen receptor α","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Key Discipline of Zhejiang Province in Medical Technology; Hospital for Sick Children; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Fulvestrant; Estrogen receptor; Breast cancer; Tamoxifen; Cancer research; PI3K/AKT/mTOR pathway; PTEN; Estrogen receptor alpha; Protein kinase B; Estrogen; Carcinogenesis; Cancer; Biology; Internal medicine; Endocrinology; Signal transduction; Medicine; Cell biology","score_opus":0.006967777413555831,"score_gpt":0.2059299169743842,"score_spread":0.19896213956082837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3172346058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97782964,0.020681813,0.00018413567,0.00009011577,0.000025364285,0.00016201085,0.00095362,0.0000090094345,0.00006432021],"genre_scores_gemma":[0.99829686,0.00063226424,0.00033592817,0.000042692864,0.00004717743,0.000017946277,0.00041113113,0.000016711063,0.00019930434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991091,0.00007308415,0.00013743831,0.0003944362,0.000093966955,0.00019199122],"domain_scores_gemma":[0.99932593,0.000013777273,0.000054753353,0.00014916687,0.00006113924,0.00039521698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000867226,0.00015758058,0.00015504101,0.000015079937,0.00009712953,0.000030818668,0.000041351494,0.00007786331,0.00003427187],"category_scores_gemma":[0.000039424547,0.00015832011,0.000050259703,0.00004375226,0.00008718595,0.000010376313,0.000052406944,0.00004829878,4.163829e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020394704,0.00012350833,0.015495463,0.00019737319,0.000025887855,0.0000037298507,0.00003873162,3.357548e-7,0.98159665,0.000028933067,0.00014994074,0.0021355012],"study_design_scores_gemma":[0.000578258,0.00009381051,0.0037361537,0.000027337739,0.000059457234,0.000016810554,0.000052193074,0.00003495129,0.99380535,0.0000838668,0.0013334241,0.00017836386],"about_ca_topic_score_codex":0.000020189866,"about_ca_topic_score_gemma":0.000002284867,"teacher_disagreement_score":0.020467235,"about_ca_system_score_codex":0.0000060006582,"about_ca_system_score_gemma":0.00014235031,"threshold_uncertainty_score":0.6456107},"labels":[],"label_agreement":null},{"id":"W3198510843","doi":"10.1038/s41419-021-04130-8","title":"A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University Health Centre; McGill University; Jewish General Hospital","funders":"National Institutes of Health; National Cancer Institute; Frederick National Laboratory for Cancer Research; U.S. Department of Health and Human Services","keywords":"PMS2; Biology; DNA mismatch repair; Microsatellite instability; Genetics; Germline mutation; RNA splicing; Germline; Missense mutation; Cancer research; Mutation; MLH1; Population; Bloom syndrome; DNA repair; Gene; Microsatellite; Medicine; Allele; Helicase","score_opus":0.041147448368705104,"score_gpt":0.27381655325343696,"score_spread":0.23266910488473186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198510843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99128795,0.0009976003,0.006253707,0.00016110278,0.00007360889,0.00030560055,0.00005418918,0.000062306135,0.00080394716],"genre_scores_gemma":[0.99251086,0.000041964013,0.0051728957,0.001000388,0.00003307947,0.00003165517,0.000026998201,0.00002356391,0.0011586187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991203,0.000016075312,0.00015761677,0.00030525686,0.0002161139,0.00018463745],"domain_scores_gemma":[0.9989877,0.000055663546,0.000040856972,0.0002809792,0.00011458545,0.0005202576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000058245503,0.00013367384,0.00022013728,0.00005165076,0.000044623655,0.000013465838,0.000031684907,0.000046814897,0.000036682013],"category_scores_gemma":[0.0001607227,0.00012117364,0.00012541101,0.000088593166,0.000025959276,0.00003337004,0.00004667086,0.00006177361,0.0000050291887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023781927,0.0012973425,0.112250924,0.003365101,0.00020728077,0.0006604986,0.0032361005,0.022773067,0.8497666,0.00023831478,0.002889641,0.00093691907],"study_design_scores_gemma":[0.008109924,0.00066166074,0.15476267,0.000586848,0.0020413843,0.0001549879,0.0013735587,0.15895145,0.6703745,0.0017453098,0.0002863444,0.00095136976],"about_ca_topic_score_codex":0.00009510068,"about_ca_topic_score_gemma":0.000047175035,"teacher_disagreement_score":0.17939211,"about_ca_system_score_codex":0.000052316824,"about_ca_system_score_gemma":0.00036212135,"threshold_uncertainty_score":0.49413174},"labels":[],"label_agreement":null},{"id":"W3202444680","doi":"10.1038/s41419-021-04202-9","title":"p53-dependent induction of P2X7 on hematopoietic stem and progenitor cells regulates hematopoietic response to genotoxic stress","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Childhood Cancer Survivors' Quality of Life","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill Genome Centre; McGill University","funders":"National Center for Advancing Translational Sciences; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Compute Canada; Canada Research Chairs; Government of Canada; McGill University","keywords":"Haematopoiesis; Progenitor cell; Bone marrow; Stem cell; Biology; Cancer research; DNA damage; Immunology; Hematopoietic stem cell; Cell biology; Bone marrow failure; Context (archaeology); Genetics","score_opus":0.019691868197101746,"score_gpt":0.27040059370715985,"score_spread":0.25070872551005813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202444680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933707,0.003995774,0.000028352451,0.0015053825,0.00018507318,0.00066157116,0.000094029434,0.00004660489,0.000112482114],"genre_scores_gemma":[0.9974326,0.00011084098,0.00018936396,0.0006695412,0.00012886769,0.000039921313,0.00001930125,0.000033929646,0.0013756334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814564,0.00020778904,0.00038782708,0.0005351754,0.00045789307,0.0002656657],"domain_scores_gemma":[0.9979249,0.00015839525,0.00010863329,0.00053728593,0.00012274768,0.0011480161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002839945,0.00023070203,0.00040756195,0.00012031042,0.00008725719,0.000040281546,0.00006447792,0.00008667619,0.000055100307],"category_scores_gemma":[0.00013940931,0.00021873646,0.00009160426,0.00016201603,0.00006842535,0.000054783628,0.00009478966,0.00012925711,0.000017991204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.034357898,0.0067560044,0.0914607,0.021553876,0.00042687697,0.0026316124,0.023281263,0.00014206338,0.80997753,0.00090382557,0.0031156512,0.0053926744],"study_design_scores_gemma":[0.0035323913,0.0007428686,0.07455518,0.0011351855,0.00043351695,0.000083098195,0.0038832813,0.000035037643,0.91422844,0.00046511283,0.0004602388,0.0004456714],"about_ca_topic_score_codex":0.000019252726,"about_ca_topic_score_gemma":0.0000051876273,"teacher_disagreement_score":0.10425086,"about_ca_system_score_codex":0.000050718423,"about_ca_system_score_gemma":0.00035195253,"threshold_uncertainty_score":0.89198136},"labels":[],"label_agreement":null},{"id":"W3203231473","doi":"10.1038/s41419-021-04197-3","title":"TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Canadian Institutes of Health Research; Amgen Canada; McMaster University; Government of Canada; Amgen","keywords":"Endocrinology; Internal medicine; Unfolded protein response; XBP1; Kidney disease; CHOP; Kidney; Fibrosis; Medicine; Albuminuria; Angiotensin II; Transforming growth factor; Cancer research; Endoplasmic reticulum; Receptor; Biology; Cell biology; RNA splicing","score_opus":0.009557904102714192,"score_gpt":0.2415574730515875,"score_spread":0.2319995689488733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203231473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921318,0.005986783,0.00030002912,0.00019408994,0.00010472687,0.000127521,0.0004045419,0.0000072711796,0.0007432123],"genre_scores_gemma":[0.99673164,0.001058849,0.00020426152,0.00030541155,0.00018696327,0.000025878076,0.0012070121,0.000014714024,0.00026527393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989904,0.00006076103,0.00021633365,0.00040236843,0.00012430335,0.0002057919],"domain_scores_gemma":[0.9988879,0.000010541432,0.00006764516,0.00028275265,0.00005869468,0.0006924877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003243516,0.00015775618,0.00014305071,0.000030868097,0.000048036876,0.000026107986,0.00008059395,0.000066576074,0.00012322735],"category_scores_gemma":[0.00022352286,0.00015475806,0.000107985055,0.000073455274,0.00007933632,0.000014083753,0.00010805658,0.00005599181,0.000004015465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018929514,0.0005747463,0.065141864,0.0008351455,0.000043759377,0.00012635198,0.00009706475,0.0009174858,0.9214805,0.0005913152,0.0070280572,0.001270809],"study_design_scores_gemma":[0.011371742,0.00067262555,0.22987056,0.0010097848,0.00048349798,0.0000053171175,0.00032194462,0.0046841446,0.7172157,0.0036690324,0.029073456,0.0016221758],"about_ca_topic_score_codex":0.000028795683,"about_ca_topic_score_gemma":0.0000059147737,"teacher_disagreement_score":0.20426473,"about_ca_system_score_codex":0.000024719073,"about_ca_system_score_gemma":0.0006985832,"threshold_uncertainty_score":0.6310851},"labels":[],"label_agreement":null},{"id":"W3203666702","doi":"10.1038/s41419-021-04177-7","title":"Negative regulation of TGFβ-induced apoptosis by RAC1B enhances intestinal tumourigenesis","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Edinburgh; Institute of Genetics; Cancer Research UK","keywords":"In vivo; Apoptosis; Biology; Cancer research; Programmed cell death; Colorectal cancer; PTEN; Cell biology; Signal transduction; Cancer; PI3K/AKT/mTOR pathway; Genetics","score_opus":0.015584948622816184,"score_gpt":0.2571359669903593,"score_spread":0.2415510183675431,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203666702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958421,0.0015186099,0.00015816522,0.00019858335,0.000104777966,0.00015963645,0.00002364462,0.000016867809,0.001977608],"genre_scores_gemma":[0.9978968,0.00011822835,0.0009000255,0.00015933452,0.00005674915,0.00002070257,0.0000364249,0.000011324669,0.00080039236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992379,0.00003758173,0.00016507789,0.00024430428,0.00018203669,0.00013312326],"domain_scores_gemma":[0.9991396,0.0000908074,0.00007036703,0.00016366398,0.00016547469,0.00037009642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000040655534,0.00011104484,0.00017953503,0.000032155887,0.000043042714,0.00001051763,0.00003315886,0.000036919006,0.00032444263],"category_scores_gemma":[0.0003868484,0.00010015383,0.00005827435,0.00012732903,0.000048706395,0.00003493745,0.000031575477,0.00005415166,0.0000049575056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046371183,0.00022942787,0.038867746,0.00023226498,0.000018084647,0.000010818876,0.00015191964,0.0000031593693,0.9551297,0.000023671335,0.0013390353,0.0035304886],"study_design_scores_gemma":[0.00060854165,0.00017726148,0.1295668,0.00007620202,0.00015760234,0.0000024688138,0.000118202974,0.00013420175,0.86850566,0.000469386,0.00009231727,0.000091334194],"about_ca_topic_score_codex":0.000029160981,"about_ca_topic_score_gemma":0.0000020920693,"teacher_disagreement_score":0.09069906,"about_ca_system_score_codex":0.00003044574,"about_ca_system_score_gemma":0.0002984998,"threshold_uncertainty_score":0.40841547},"labels":[],"label_agreement":null},{"id":"W3210016719","doi":"10.1038/s41419-021-04321-3","title":"Paradoxical implication of BAX/BAK in the persistence of tetraploid cells","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Labex Immuno-Oncology; Ligue Contre le Cancer; Ministerio de Ciencia e Innovación; Institut Universitaire de France; Fondation pour la Recherche Médicale; Institut National Du Cancer; Institut National de la Santé et de la Recherche Médicale; European Commission; Institut Gustave-Roussy; Fondation Leducq; Agence Nationale de la Recherche; Centre National de la Recherche Scientifique; Junta de Castilla y León; Equipex; Université de Paris; Seerave Foundation","keywords":"Persistence (discontinuity); Cell biology; Biology; Chemistry","score_opus":0.016583737712329096,"score_gpt":0.23418970444559598,"score_spread":0.21760596673326688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210016719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942354,0.0035923996,0.000089893016,0.00007762952,0.000014525357,0.000086397115,0.000043529777,0.000001159927,0.0018590629],"genre_scores_gemma":[0.99913085,0.00040687877,0.00014359919,0.00015149794,0.000023169156,0.000010224308,0.00004592415,0.0000032421026,0.00008459581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99956214,0.000046639325,0.00010388328,0.00014360476,0.00006184051,0.00008191481],"domain_scores_gemma":[0.9996308,0.000014199883,0.0000335313,0.00020246767,0.00003341647,0.0000855722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007027752,0.00005290399,0.00006539919,0.0000110355595,0.00001840073,0.0000050453637,0.00007741071,0.00003599395,0.000012060939],"category_scores_gemma":[0.00004129866,0.00004105846,0.000051353938,0.000050605315,0.000044843266,0.0000014750112,0.000029680255,0.000030395835,9.174633e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007075753,0.00016372044,0.011101432,0.00011435659,0.0000036128429,0.000007789622,0.000091001,0.00000442448,0.9873518,0.00031451476,0.00013385867,0.0006427378],"study_design_scores_gemma":[0.0002949143,0.000071571274,0.024477351,0.00001117152,0.0000187954,0.000002854651,0.00021034408,0.000030710857,0.973014,0.00040225429,0.0014030372,0.0000629974],"about_ca_topic_score_codex":0.000003958186,"about_ca_topic_score_gemma":0.0000013596094,"teacher_disagreement_score":0.014337798,"about_ca_system_score_codex":0.0000013902213,"about_ca_system_score_gemma":0.0000802919,"threshold_uncertainty_score":0.16743155},"labels":[],"label_agreement":null},{"id":"W3215804598","doi":"10.1038/s41419-021-04273-8","title":"Lipid droplets contribute myogenic differentiation in C2C12 by promoting the remodeling of the acstin-filament","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Fundamental Research Funds for the Central Universities; National Natural Science Foundation of China","keywords":"Cell biology; Myogenesis; C2C12; Actin; Lipid droplet; Biology; Myocyte; Myosin; Skeletal muscle; Organelle; Actin remodeling; Cytoskeleton; Actin cytoskeleton; Cell; Biochemistry; Anatomy","score_opus":0.005792009533665544,"score_gpt":0.19865691209548575,"score_spread":0.1928649025618202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215804598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937099,0.0054730927,0.00016594642,0.0003079767,0.00009170178,0.00014453559,0.000042769883,0.0000025867612,0.000061468396],"genre_scores_gemma":[0.99896926,0.00037803347,0.000027531443,0.00021731266,0.0001051471,0.000010112234,0.0000744898,0.0000068543823,0.00021123432],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992721,0.000115760515,0.00017016083,0.0002019914,0.00009542709,0.00014457919],"domain_scores_gemma":[0.9995162,0.000018142337,0.00007353129,0.00024637656,0.00004454695,0.00010123847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001560743,0.00008871555,0.000092395094,0.000008144123,0.000083751904,0.0000207726,0.00009870916,0.000038114944,0.0000062599534],"category_scores_gemma":[0.00023574215,0.00005273858,0.00006809118,0.000050446888,0.00002224682,0.0000028300044,0.00011862027,0.000047112433,5.5542523e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040451767,0.00011396737,0.018420774,0.000054156346,0.000010221373,9.765165e-7,0.00005332215,0.000011656125,0.9790131,0.00001787209,0.00018415808,0.002079365],"study_design_scores_gemma":[0.00053781905,0.000010882396,0.03131355,0.000032145326,0.000074556134,0.0000011135629,0.00005661043,0.0010532625,0.96161175,0.00004350103,0.005162529,0.00010225805],"about_ca_topic_score_codex":0.0000055329533,"about_ca_topic_score_gemma":0.000006287013,"teacher_disagreement_score":0.017401306,"about_ca_system_score_codex":0.000004561147,"about_ca_system_score_gemma":0.00009865688,"threshold_uncertainty_score":0.21506168},"labels":[],"label_agreement":null},{"id":"W3216621190","doi":"10.1038/s41419-021-04423-y","title":"Hippo signaling suppresses tumor cell metastasis via a Yki-Src42A positive feedback loop","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Tongji University; National Key Research and Development Program of China; Key Technology Research and Development Program of Shandong; Institute of Genetics; National Natural Science Foundation of China; University of Texas Southwestern Medical Center","keywords":"Hippo signaling pathway; Cancer research; Metastasis; Proto-oncogene tyrosine-protein kinase Src; Cell migration; Biology; Cell growth; Cell biology; Oncogene; Signal transduction; Cell; Cancer; Cell cycle; Genetics","score_opus":0.0089338132974408,"score_gpt":0.21830078834005154,"score_spread":0.20936697504261073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3216621190","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981733,0.014035034,0.0014491398,0.00009012446,0.00010591572,0.00014389129,0.00033832653,0.00002533933,0.0020791837],"genre_scores_gemma":[0.9951361,0.00023727963,0.0007165302,0.0009105224,0.00020186945,0.000021493875,0.00066765107,0.000038561087,0.0020700216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845403,0.0001300369,0.00021676804,0.00063746196,0.00016257801,0.00039913878],"domain_scores_gemma":[0.9985855,0.00003589848,0.00007500987,0.00037486915,0.00015762723,0.0007710785],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000102471924,0.0002767357,0.00022709562,0.000039555125,0.00018313012,0.000092022005,0.00013274088,0.00008642578,0.00015577447],"category_scores_gemma":[0.00008814449,0.00026991635,0.0001838288,0.00010103708,0.00006672209,0.000008363221,0.00013662555,0.00009571705,0.000035695866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021519072,0.0002830875,0.001659202,0.00016521006,0.000046648664,0.00041213434,0.000067284396,0.000071817856,0.99584484,0.000013988538,0.00050481095,0.00071581075],"study_design_scores_gemma":[0.000920484,0.00013970982,0.0004302167,0.00003438216,0.00025099414,0.000019268136,0.00018801545,0.00016449936,0.9931855,0.00026596835,0.0039992356,0.00040172355],"about_ca_topic_score_codex":0.000018351759,"about_ca_topic_score_gemma":0.0000031165632,"teacher_disagreement_score":0.0137977535,"about_ca_system_score_codex":0.000009675237,"about_ca_system_score_gemma":0.0003093488,"threshold_uncertainty_score":0.9999753},"labels":[],"label_agreement":null},{"id":"W3216848432","doi":"10.1038/s41419-021-04402-3","title":"Misoprostol treatment prevents hypoxia-induced cardiac dysfunction through a 14-3-3 and PKA regulatory motif on Bnip3","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada; St. Boniface Hospital; Research Institute in Oncology and Hematology; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada; Heart and Stroke Foundation of Canada","keywords":"Hypoxia (environmental); Phosphorylation; Cell biology; Homeostasis; Misoprostol; Biology; Programmed cell death; Mitochondrion; Pharmacology; Endocrinology; Internal medicine; Chemistry; Medicine; Apoptosis; Biochemistry","score_opus":0.015777285169837483,"score_gpt":0.23578300289828752,"score_spread":0.22000571772845004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3216848432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99150896,0.0041542035,0.00010055416,0.000100670804,0.0007184898,0.0002438337,0.000052388088,0.000014650741,0.0031062567],"genre_scores_gemma":[0.9883805,0.0011007367,0.00016063824,0.00066678337,0.00042594064,0.000054771917,0.00036065374,0.000019408231,0.008830551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903893,0.00009642528,0.000119076794,0.00049029785,0.00007983753,0.00017541973],"domain_scores_gemma":[0.99926674,0.0000107631595,0.00003878702,0.0003251603,0.000038781374,0.00031978727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000034262852,0.00017485839,0.0001515436,0.000018400751,0.00011643803,0.000024639108,0.00002763494,0.0001233646,0.000038902188],"category_scores_gemma":[0.00005282104,0.00015676951,0.00009465541,0.00003515272,0.00003070163,0.0000050209533,0.000039445247,0.00004596735,0.000013155936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011992996,0.0005477696,0.012910944,0.00009806329,0.00009397242,0.00008785029,0.00012481793,0.000016013475,0.97050613,0.00047584233,0.004755367,0.0091839135],"study_design_scores_gemma":[0.0075350525,0.0027186186,0.078118786,0.000059223046,0.0005982445,0.000050031707,0.00023795523,0.000062549494,0.6114667,0.0016637403,0.29652664,0.00096245075],"about_ca_topic_score_codex":0.000010657707,"about_ca_topic_score_gemma":0.0000029722435,"teacher_disagreement_score":0.35903946,"about_ca_system_score_codex":0.000015390335,"about_ca_system_score_gemma":0.00011884546,"threshold_uncertainty_score":0.63928753},"labels":[],"label_agreement":null},{"id":"W4200491621","doi":"10.1038/s41419-021-04457-2","title":"CDK5RAP2 loss-of-function causes premature cell senescence via the GSK3β/β-catenin-WIP1 pathway","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; University of Calgary","keywords":"Downregulation and upregulation; Gene knockdown; Phosphorylation; Cell biology; Senescence; GSK-3; Biology; GSK3B; Phosphatase; Chemistry; Cell culture; Biochemistry; Genetics; Gene","score_opus":0.006944908622518815,"score_gpt":0.19680559794603888,"score_spread":0.18986068932352007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200491621","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98805785,0.009738116,0.0005589053,0.00012707581,0.00016340041,0.00014186169,0.000042046555,0.0000070845135,0.0011636473],"genre_scores_gemma":[0.9961765,0.0015249839,0.000102619386,0.00065451005,0.000029095509,0.000013089509,0.00015912311,0.00001600478,0.0013240976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991997,0.000042050764,0.00013456379,0.00033456535,0.0001110481,0.00017811012],"domain_scores_gemma":[0.9993762,0.000009403968,0.00005529441,0.00027655542,0.00007487305,0.00020768418],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000038551312,0.00014854192,0.00009223651,0.000014114659,0.00010735055,0.000025689184,0.00009758727,0.0000677118,0.000022291846],"category_scores_gemma":[0.000027467562,0.00011491567,0.000074301955,0.00007104701,0.000066829765,0.0000032453565,0.0001125685,0.000059690938,0.0000059229255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013625537,0.00017150209,0.021907134,0.00015006197,0.000014540031,0.000025315612,0.00004262494,0.000045543602,0.97595036,0.00004039192,0.00088392594,0.0006323518],"study_design_scores_gemma":[0.00066997734,0.00012333869,0.14984728,0.000017983331,0.0000838051,0.00000898628,0.000119713695,0.000069968584,0.83425736,0.0005362819,0.013977754,0.0002875663],"about_ca_topic_score_codex":0.000004585035,"about_ca_topic_score_gemma":0.000006038666,"teacher_disagreement_score":0.14169301,"about_ca_system_score_codex":0.0000027978315,"about_ca_system_score_gemma":0.00017271977,"threshold_uncertainty_score":0.4686125},"labels":[],"label_agreement":null},{"id":"W4210440333","doi":"10.1038/s41419-022-04576-4","title":"PGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute on Alcohol Abuse and Alcoholism; Chengdu Science and Technology Program; Chengdu Science and Technology Bureau; National Natural Science Foundation of China","keywords":"Sorafenib; Glycolysis; MAPK/ERK pathway; Carcinogenesis; Cancer research; Signal transduction; Cell biology; Anaerobic glycolysis; Cell growth; Chemistry; Biology; Biochemistry; Metabolism; Gene; Hepatocellular carcinoma","score_opus":0.01722397889470673,"score_gpt":0.22243533102727656,"score_spread":0.20521135213256983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210440333","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98494184,0.013420569,0.00014308683,0.00017105717,0.00003307429,0.0006349731,0.00009619993,0.000028122657,0.00053107267],"genre_scores_gemma":[0.9976249,0.000047595506,0.0011984421,0.0002714597,0.00006094091,0.00010742285,0.0000455298,0.000036619705,0.000607142],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982417,0.000118981974,0.00038703374,0.0005676262,0.00032925472,0.00035535547],"domain_scores_gemma":[0.99845064,0.00021411442,0.00017495707,0.00028114242,0.00009721714,0.00078194466],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023199288,0.00026862154,0.00046838282,0.00016582636,0.00046908492,0.000053757958,0.00007316125,0.000038147275,0.00005554961],"category_scores_gemma":[0.00010189965,0.00025222424,0.000092648654,0.00025428555,0.000059452217,0.00007592962,0.0002107127,0.00015427366,0.0000010132435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0056696692,0.00046617657,0.28587678,0.0013950334,0.000081436345,0.000922572,0.0011178841,0.00018377969,0.70108676,0.000080028374,0.00019449677,0.0029254146],"study_design_scores_gemma":[0.008093222,0.0015345617,0.26573524,0.00022768808,0.0010971861,0.000032132342,0.0021206297,0.0017782554,0.7170147,0.0005482055,0.0010716921,0.00074652716],"about_ca_topic_score_codex":0.000087896784,"about_ca_topic_score_gemma":0.0000049951946,"teacher_disagreement_score":0.020141516,"about_ca_system_score_codex":0.00010435762,"about_ca_system_score_gemma":0.00019289869,"threshold_uncertainty_score":0.999993},"labels":[],"label_agreement":null},{"id":"W4212876904","doi":"10.1038/s41419-022-04591-5","title":"Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; Université de Montréal; Université Laval; Centre Hospitalier de l’Université de Montréal; Centre hospitalier universitaire de Québec; Institute for Research in Immunology and Cancer; Translational Research in Oncology","funders":"Institute of Nutrition, Metabolism and Diabetes; Université de Montréal; Government of Canada; Fonds de Recherche du Québec - Santé; Kidney Foundation of Canada; Natural Sciences and Engineering Research Council of Canada; Fondation Jean-Louis Lévesque; Canadian Institutes of Health Research; Genome Canada","keywords":"Microvesicles; Cell biology; Apoptosis; Biogenesis; Caspase; Chemistry; Caspase 3; Caspase 8; Biology; Programmed cell death; microRNA; Biochemistry","score_opus":0.004918384888852491,"score_gpt":0.19793511040506362,"score_spread":0.19301672551621113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212876904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90266955,0.09645359,0.000051974905,0.00019568544,0.000037493595,0.00024291898,0.00027480192,0.00000849639,0.00006545922],"genre_scores_gemma":[0.99776125,0.001331538,0.0000506619,0.0003907289,0.00003896925,0.000059634433,0.00005516901,0.00002042847,0.00029159928],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990484,0.00013199575,0.00016922677,0.00033190555,0.00012475972,0.00019372824],"domain_scores_gemma":[0.9991089,0.000041819574,0.00007911913,0.00038123663,0.000025402413,0.00036352995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012534014,0.00015638431,0.00014165102,0.00003753279,0.00027403614,0.000024606688,0.00013337213,0.000033754262,0.000027121541],"category_scores_gemma":[0.000081567705,0.00012929903,0.00007961244,0.00005932395,0.00020922144,0.000004719553,0.0002486811,0.000060528615,7.4856683e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001605496,0.0004589298,0.16828957,0.00036483747,0.0001903036,0.000120429155,0.00013699601,0.00013670353,0.82294005,0.00080683647,0.0009057213,0.0040441053],"study_design_scores_gemma":[0.01845168,0.0020771667,0.7184614,0.00006503045,0.0037509701,0.00022847377,0.002663033,0.0058899927,0.21449897,0.0051611876,0.026175704,0.0025763854],"about_ca_topic_score_codex":0.000031710963,"about_ca_topic_score_gemma":0.0000016014955,"teacher_disagreement_score":0.6084411,"about_ca_system_score_codex":0.0000062404674,"about_ca_system_score_gemma":0.00010981461,"threshold_uncertainty_score":0.52726614},"labels":[],"label_agreement":null},{"id":"W4214626746","doi":"10.1038/s41419-022-04641-y","title":"Dichotomy in hypoxia-induced mitochondrial fission in placental mesenchymal cells during development and preeclampsia: consequences for trophoblast mitochondrial homeostasis","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institutes of Health; Government of Canada; U.S. Department of Health and Human Services","keywords":"Trophoblast; Hypoxia (environmental); Cell biology; Mitochondrion; Preeclampsia; Mitochondrial fission; Homeostasis; Mesenchymal stem cell; Placenta; Biology; Andrology; Chemistry; Fetus; Pregnancy; Medicine; Oxygen; Genetics","score_opus":0.012437664952049956,"score_gpt":0.2274341738683789,"score_spread":0.21499650891632896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214626746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99697644,0.00095461286,0.000083490326,0.000070957074,0.00083464157,0.0008446209,0.00012017217,0.000009671354,0.00010540263],"genre_scores_gemma":[0.9972917,0.00009884854,0.001167822,0.000107713626,0.0002370802,0.00044599082,0.00021423015,0.00002028158,0.00041633047],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984675,0.00014119926,0.00029828626,0.00060825126,0.00014113,0.00034365535],"domain_scores_gemma":[0.99936384,0.000034305813,0.00007578756,0.00016304327,0.000017904906,0.00034513848],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000787774,0.00021403604,0.00020880332,0.00013693544,0.00024133193,0.00003218195,0.00010566903,0.000105703235,0.000052111154],"category_scores_gemma":[0.0000756568,0.00021858372,0.000061398976,0.00009292148,0.00006421959,0.000009590732,0.00018036715,0.00014350102,0.0000013826533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0052142697,0.00018636897,0.0061988374,0.00008521436,0.000011131084,0.00010238886,0.00029606468,0.00006359298,0.9869597,0.000018500587,0.00045041178,0.00041349762],"study_design_scores_gemma":[0.027926013,0.0014713262,0.03399944,0.00007070895,0.00009743733,0.00008525928,0.0024700733,0.00030591313,0.8973414,0.0003119084,0.034547683,0.0013728956],"about_ca_topic_score_codex":0.000022506134,"about_ca_topic_score_gemma":0.000058719612,"teacher_disagreement_score":0.08961838,"about_ca_system_score_codex":0.00004542679,"about_ca_system_score_gemma":0.00028629927,"threshold_uncertainty_score":0.89135855},"labels":[],"label_agreement":null},{"id":"W4220757956","doi":"10.1038/s41419-022-04653-8","title":"Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"Genentech; Karolinska Institutet; Israel Science Foundation; Radiumhemmets Forskningsfonder; Cancerfonden; Deutsche Forschungsgemeinschaft; Wellcome Trust; Ontario Genomics Institute; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Genomics; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; McGill University; Bayer; Science for Life Laboratory; Vetenskapsrådet; Pfizer","keywords":"Biology; DNA-binding domain; Gene; Genetics; Transcription factor; Protein family; Mutant; Gene family; DNA; Thermostability; Mutation; Molecular evolution; Phylogenetic tree; Computational biology; Genome; Biochemistry","score_opus":0.0120301736932414,"score_gpt":0.20524282204913286,"score_spread":0.19321264835589147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220757956","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96039826,0.03181549,0.000027160728,0.00015434272,0.0005649356,0.00028780242,0.00016489734,0.00003367591,0.0065534315],"genre_scores_gemma":[0.99707603,0.000080765036,0.00009219712,0.0011419518,0.00008531209,0.00003097617,0.00020085802,0.000023176744,0.001268713],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99893254,0.000112072594,0.00017464372,0.00031247688,0.00030323694,0.00016500452],"domain_scores_gemma":[0.9989421,0.000028303817,0.00008611227,0.00046939356,0.00003250888,0.00044162117],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004219499,0.00013397446,0.00017753131,0.00008491585,0.00016273545,0.0000036279341,0.00012981941,0.00004293079,0.00020192913],"category_scores_gemma":[0.000027505022,0.000112169226,0.00012392437,0.000107583764,0.00011862874,0.000039294035,0.00015707558,0.00020216139,0.0000057777443],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039162287,0.0028017736,0.06454392,0.00041340015,0.0002665164,0.0030012224,0.0052877665,0.00042526063,0.82061017,0.003900628,0.093502514,0.0013306005],"study_design_scores_gemma":[0.013127231,0.0012329308,0.66648245,0.00023251909,0.0018983108,0.00010556859,0.0029831962,0.0032192483,0.0035742146,0.014694271,0.29129666,0.0011534357],"about_ca_topic_score_codex":0.00015125664,"about_ca_topic_score_gemma":0.0000032317819,"teacher_disagreement_score":0.817036,"about_ca_system_score_codex":0.00047577443,"about_ca_system_score_gemma":0.00085534883,"threshold_uncertainty_score":0.4574128},"labels":[],"label_agreement":null},{"id":"W4223429273","doi":"10.1038/s41419-022-04784-y","title":"Simvastatin rescues memory and granule cell maturation through the Wnt/β-catenin signaling pathway in a mouse model of Alzheimer’s disease","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Ottawa; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; University of California, San Francisco; National Natural Science Foundation of China; Canadian Institutes of Health Research; Alzheimer Society; Government of Canada; Canadian Vascular Network; Gladstone Institutes","keywords":"Wnt signaling pathway; Dentate gyrus; Neurogenesis; DKK1; Doublecortin; Hippocampal formation; Biology; Endocrinology; Internal medicine; Catenin; Granule cell; Nestin; Signal transduction; Cell biology; Medicine; Neural stem cell; Stem cell","score_opus":0.04096190915549178,"score_gpt":0.28147537686717317,"score_spread":0.2405134677116814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223429273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95831573,0.039228346,0.000036351892,0.00038279843,0.000017164446,0.00092739146,0.00063332246,0.000029330982,0.0004295515],"genre_scores_gemma":[0.99831086,0.00038281985,0.00018506552,0.00028576748,0.000025067111,0.00023296836,0.0003043738,0.000030362531,0.00024271739],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99835783,0.00017145327,0.00028391145,0.00039201204,0.00046007705,0.00033469815],"domain_scores_gemma":[0.9986869,0.00008276334,0.00009237488,0.00026644726,0.000055797365,0.00081570377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016502074,0.00021302173,0.0002507957,0.000096646145,0.00029073705,0.000033095526,0.00008620279,0.000025275647,0.00006150783],"category_scores_gemma":[0.000044921908,0.0001563666,0.00010301045,0.0001388162,0.00012735238,0.00015333992,0.00014917814,0.00018854978,0.0000034801924],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.168485,0.052043557,0.38261652,0.012790851,0.008710444,0.01301807,0.041862383,0.10192433,0.18073551,0.007464428,0.009689787,0.02065911],"study_design_scores_gemma":[0.068392485,0.003295672,0.14288074,0.00069964747,0.01362344,0.000036352696,0.021643758,0.43310577,0.24291396,0.06920812,0.00036312948,0.0038369275],"about_ca_topic_score_codex":0.00014550114,"about_ca_topic_score_gemma":0.0000029336986,"teacher_disagreement_score":0.33118144,"about_ca_system_score_codex":0.000035114703,"about_ca_system_score_gemma":0.0005001542,"threshold_uncertainty_score":0.6376445},"labels":[],"label_agreement":null},{"id":"W4223948344","doi":"10.1038/s41419-022-04813-w","title":"Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Associazione Italiana per la Ricerca sul Cancro; Fondazione Telethon; University of South Australia; Deutsche Forschungsgemeinschaft; Department of Science and Technology, Ministry of Science and Technology, India; JSS College of Pharmacy; Australian Cancer Research Foundation; Fondazione Umberto Veronesi; Neurosurgical Research Foundation","keywords":"Cancer; Cancer research; Cancer cell; Cell biology; Biology; Chemistry; Genetics","score_opus":0.015088630086490556,"score_gpt":0.2614749669088657,"score_spread":0.24638633682237512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223948344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812238,0.012802418,0.000044736767,0.0012326821,0.00039741592,0.0006729205,0.0015617958,0.000109470784,0.0019547374],"genre_scores_gemma":[0.9864695,0.0006307404,0.000030145027,0.008802218,0.00018951818,0.00029348198,0.0002697526,0.000042747906,0.0032719006],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99845713,0.000085862855,0.00020321835,0.00045170408,0.00040188414,0.00040018934],"domain_scores_gemma":[0.9975674,0.000075843454,0.000059106525,0.00036969173,0.000056272398,0.0018716735],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008175928,0.00023193168,0.0002844874,0.00012070714,0.00024858164,0.00002349259,0.00013873515,0.00003857813,0.0030075375],"category_scores_gemma":[0.0000341242,0.00021428632,0.00011685616,0.00023101394,0.000041474377,0.000051416144,0.00013225233,0.00016790217,0.00007614499],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.036881715,0.015566017,0.37925595,0.0033130057,0.001770787,0.019655798,0.008555768,0.0049445513,0.14836116,0.002568126,0.33958834,0.03953874],"study_design_scores_gemma":[0.025030207,0.0025098182,0.52876157,0.00030385546,0.0028967354,0.000023619406,0.0037728602,0.0057070944,0.08062598,0.0023442227,0.34509173,0.0029323252],"about_ca_topic_score_codex":0.00024400055,"about_ca_topic_score_gemma":0.000009443537,"teacher_disagreement_score":0.14950559,"about_ca_system_score_codex":0.000081345635,"about_ca_system_score_gemma":0.00044727852,"threshold_uncertainty_score":0.9979038},"labels":[],"label_agreement":null},{"id":"W4224281380","doi":"10.1038/s41419-022-04854-1","title":"p63, a key regulator of Ago2, links to the microRNA-144 cluster","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heritage Medical Research Clinic; University of Alberta","funders":"Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Kids With Cancer Society; University of Alberta; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Regulator; microRNA; Key (lock); Computational biology; Cluster (spacecraft); Cell biology; Biology; Computer science; Genetics; Computer network; Gene; Ecology","score_opus":0.006545989143386149,"score_gpt":0.21581182149202743,"score_spread":0.2092658323486413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224281380","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939773,0.0038014473,0.00034217787,0.00085773034,0.000093839764,0.0003366271,0.00018932765,0.000006999387,0.0003945714],"genre_scores_gemma":[0.99633753,0.000028600749,0.00015355035,0.0017430153,0.00012506217,0.000059111135,0.00017413907,0.000017216325,0.001361771],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992208,0.000074521995,0.00014626666,0.00027168187,0.00012576072,0.00016096659],"domain_scores_gemma":[0.9991579,0.000008447993,0.000061680454,0.00041497167,0.00004032755,0.00031667878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011249111,0.00010946832,0.00008478231,0.000031688927,0.00015069415,0.000015903792,0.00017117515,0.000047438214,0.00007624073],"category_scores_gemma":[0.000045741162,0.0000909038,0.0000883037,0.000070436734,0.00003740399,0.0000021721773,0.00031074166,0.00007221153,0.000006432687],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018652368,0.00045320133,0.019477963,0.00022604373,0.00007381649,0.000017755623,0.00034592042,0.0021755975,0.8803691,0.00031598157,0.09203546,0.0026439184],"study_design_scores_gemma":[0.0029182057,0.0004964699,0.112853795,0.000029584946,0.00031691184,0.00001841288,0.0002866688,0.0013379593,0.123262994,0.00086235115,0.75686187,0.0007547937],"about_ca_topic_score_codex":0.000007801555,"about_ca_topic_score_gemma":0.000002163159,"teacher_disagreement_score":0.7571061,"about_ca_system_score_codex":0.0000126870855,"about_ca_system_score_gemma":0.00012254923,"threshold_uncertainty_score":0.37069494},"labels":[],"label_agreement":null},{"id":"W4248383119","doi":"10.1038/cddis.2014.435","title":"Erratum: Dysfunction of the stress-responsive FOXC1 transcription factor contributes to the earlier-onset glaucoma observed in Axenfeld-Rieger syndrome patients","year":2014,"lang":"en","type":"erratum","venue":"Cell Death and Disease","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Glaucoma; Ophthalmology; Transcription factor; Medicine; Bioinformatics; Biology; Genetics; Gene","score_opus":0.01091325159074261,"score_gpt":0.21649063041156646,"score_spread":0.20557737882082386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4248383119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98597974,0.0037830905,0.000030181502,0.001812698,0.004728985,0.0018484887,0.0010185966,0.00002313648,0.0007750772],"genre_scores_gemma":[0.9754918,0.00022512961,0.00000383627,0.0011756276,0.000105843676,0.000096927426,0.0011400348,0.000043872344,0.021716906],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99789023,0.0002915269,0.0004699232,0.00047753932,0.00047087073,0.00039990828],"domain_scores_gemma":[0.9983561,0.00011564623,0.0002080532,0.0006070421,0.00023675527,0.00047637968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001297044,0.00041075744,0.0005960511,0.00018411041,0.0001648496,0.000043948934,0.00023336048,0.00034161948,0.00005730402],"category_scores_gemma":[0.0005402213,0.00023632667,0.00030896,0.00028370827,0.00013825663,0.00005618753,0.0000727982,0.000607286,0.000017191102],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027611512,0.0005580824,0.76347375,0.0011216605,0.0000738248,0.00003962201,0.00029753032,0.0000014928493,0.00012959061,0.000024434377,0.23129268,0.00022619688],"study_design_scores_gemma":[0.0026012098,0.00045720895,0.9658214,0.00095560396,0.00054370303,0.0000030659924,0.00015252117,0.0000788186,0.000028314893,0.00022167448,0.028899098,0.0002373784],"about_ca_topic_score_codex":0.0001922685,"about_ca_topic_score_gemma":0.00019197557,"teacher_disagreement_score":0.20239358,"about_ca_system_score_codex":0.00007160076,"about_ca_system_score_gemma":0.00039772392,"threshold_uncertainty_score":0.9637122},"labels":[],"label_agreement":null},{"id":"W4249689740","doi":"10.1038/s41419-020-02957-1","title":"Correction: Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway","year":2020,"lang":"en","type":"erratum","venue":"Cell Death and Disease","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University; Health Sciences North","funders":"","keywords":"Blocking (statistics); Calcium-sensing receptor; Proteasome; Ubiquitin; Cell biology; Calcium; Energy metabolism; Carbohydrate metabolism; Chemistry; Receptor; Calcium signaling; Signal transduction; Calcium metabolism; Biology; Endocrinology; Biochemistry; Computer science","score_opus":0.014169700028859937,"score_gpt":0.22254518581170646,"score_spread":0.2083754857828465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249689740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3865155,0.17376284,0.01650965,0.01100863,0.25693664,0.017752789,0.0011384033,0.00505286,0.13132268],"genre_scores_gemma":[0.6249951,0.0012960086,0.000814749,0.0077150683,0.017055893,0.00068717805,0.0047273356,0.00049375143,0.3422149],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968097,0.0002018118,0.0005525901,0.0011221883,0.00062048674,0.0006932204],"domain_scores_gemma":[0.99658585,0.00009804174,0.00033455552,0.0005223584,0.0002463705,0.0022128224],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012472959,0.00079824345,0.0011497231,0.00025310606,0.000359428,0.00013291348,0.00010580627,0.0005773695,0.00038850275],"category_scores_gemma":[0.00082885916,0.00070705696,0.0003332648,0.00037927367,0.00008201972,0.0001142951,0.00013405744,0.0010124224,0.00008416865],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003412579,0.0011286505,0.0006477699,0.0055795033,0.0005938205,0.0014842701,0.00034299397,0.0000077194545,0.05405046,0.00018139619,0.85752183,0.07504898],"study_design_scores_gemma":[0.0048365425,0.00054335536,0.0019306269,0.00163811,0.0017873376,0.000054430937,0.00013998678,0.007535386,0.050223872,0.0003841094,0.92939425,0.0015319714],"about_ca_topic_score_codex":0.00034817302,"about_ca_topic_score_gemma":0.0000046182317,"teacher_disagreement_score":0.23988076,"about_ca_system_score_codex":0.00011416917,"about_ca_system_score_gemma":0.0013090022,"threshold_uncertainty_score":0.99953806},"labels":[],"label_agreement":null},{"id":"W4280496463","doi":"10.1038/s41419-022-04919-1","title":"Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Alberta Bone and Joint Health Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Aggrecan; Cartilage; Osteoarthritis; Synovial joint; Cell biology; Extracellular matrix; Progenitor cell; Type II collagen; Regeneration (biology); Chemistry; Medicine; Anatomy; Pathology; Biology; Stem cell; Articular cartilage","score_opus":0.02175346590046783,"score_gpt":0.21472152582690848,"score_spread":0.19296805992644064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280496463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98517615,0.012916743,0.0000014573221,0.000093075076,0.00014243815,0.00070489774,0.00022066811,0.00013700961,0.00060756854],"genre_scores_gemma":[0.9982846,0.00018507114,0.00033529373,0.00020117451,0.00011603306,0.00016078337,0.00012583513,0.000024258074,0.00056697935],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988905,0.000050293605,0.00015035813,0.0003810194,0.00022072217,0.00030708246],"domain_scores_gemma":[0.9987678,0.000025389281,0.000048556893,0.00023104512,0.000032201253,0.00089502253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007741558,0.0001873384,0.0002374087,0.00007297667,0.00040458993,0.000022446351,0.000035964524,0.000034959114,0.00016211128],"category_scores_gemma":[0.000041801137,0.00017397558,0.00011300082,0.00008021866,0.000071011505,0.00005348425,0.000100021025,0.00009882357,0.000004487198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00915995,0.0035408502,0.19772905,0.0014793582,0.00025348138,0.016557563,0.004910301,0.0000046149225,0.6925409,0.0014310547,0.0014281978,0.070964694],"study_design_scores_gemma":[0.051218763,0.022192575,0.054288015,0.00032388986,0.007512649,0.003462669,0.005958553,0.000589237,0.82149017,0.00608819,0.023796039,0.0030792267],"about_ca_topic_score_codex":0.00003148427,"about_ca_topic_score_gemma":0.0000055287683,"teacher_disagreement_score":0.14344104,"about_ca_system_score_codex":0.000052713738,"about_ca_system_score_gemma":0.0001559979,"threshold_uncertainty_score":0.70945185},"labels":[],"label_agreement":null},{"id":"W4281606500","doi":"10.1038/s41419-022-04977-5","title":"The LCK-14-3-3ζ-TRPM8 axis regulates TRPM8 function/assembly and promotes pancreatic cancer malignancy","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Wuhan Science and Technology Project; Young Scientists Fund; National Natural Science Foundation of China; National Science Foundation","keywords":"Malignancy; Pancreatic cancer; TRPM8; Function (biology); Cancer research; Cell biology; Chemistry; Cancer; Biology; Biochemistry; Genetics; Transient receptor potential channel; Receptor","score_opus":0.016835727528884313,"score_gpt":0.22981744307127247,"score_spread":0.21298171554238815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281606500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98718333,0.009624725,0.000012038943,0.0011362013,0.00069916056,0.0003740544,0.0000868029,0.00006248377,0.00082122703],"genre_scores_gemma":[0.98792803,0.0014943086,0.0000060162447,0.0005446552,0.00012513719,0.00022055767,0.0000064167534,0.000021159292,0.009653727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868625,0.0001380916,0.00015957434,0.0004421741,0.00024837433,0.00032555644],"domain_scores_gemma":[0.99919105,0.00016577846,0.000074214986,0.00014654371,0.00002325752,0.00039917912],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00011896713,0.00017256507,0.00013368188,0.0000437459,0.0014382256,0.00012938885,0.00013736423,0.000026448699,0.00021227865],"category_scores_gemma":[0.00011567502,0.00011530465,0.00006189803,0.0001723956,0.00012426112,0.00010288572,0.00015319987,0.000118621654,0.0000082997885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005025473,0.0023674879,0.06711733,0.002042681,0.00012336849,0.0006347881,0.0055875718,0.0011580498,0.7346994,0.025143767,0.06665312,0.08944693],"study_design_scores_gemma":[0.009566169,0.002655399,0.117610894,0.00033803884,0.0015468709,0.00013358418,0.0043918574,0.028379232,0.5387407,0.080538586,0.21195641,0.00414227],"about_ca_topic_score_codex":0.000049540573,"about_ca_topic_score_gemma":0.0000042815104,"teacher_disagreement_score":0.19595875,"about_ca_system_score_codex":0.000024027555,"about_ca_system_score_gemma":0.00012400054,"threshold_uncertainty_score":0.9998618},"labels":[],"label_agreement":null},{"id":"W4286511893","doi":"10.1038/s41419-022-05059-2","title":"SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Natural Sciences and Engineering Research Council of Canada; Kidney Foundation of Canada; Canadian Society of Nephrology; Government of Canada; Fondation de l’Hôpital Maisonneuve-Rosemont; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Epithelial–mesenchymal transition; Extracellular matrix; Renal cell carcinoma; Mesenchymal stem cell; Metastasis; Cell biology; Cancer; Cancer cell; Cancer research; Cell; Pathology; Biology; Medicine; Biochemistry","score_opus":0.019595442659190315,"score_gpt":0.2525107821407227,"score_spread":0.2329153394815324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286511893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952981,0.0024916963,0.00011019466,0.00015161038,0.00008886906,0.0007772873,0.000670799,0.00001688822,0.00039458755],"genre_scores_gemma":[0.998424,0.00013443528,0.0006312511,0.00022438771,0.00007620203,0.00007900747,0.00013195493,0.0000267561,0.00027201293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858123,0.00013354118,0.00030064417,0.00041523422,0.00028096137,0.00028836203],"domain_scores_gemma":[0.998989,0.000034619494,0.00009025289,0.00023281315,0.000040587005,0.0006127135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023779392,0.00019852375,0.00035168207,0.00017208289,0.0001026483,0.000017263153,0.000060092316,0.00002607549,0.0002617694],"category_scores_gemma":[0.000013351012,0.00018104127,0.00008206776,0.00019330795,0.000081117156,0.00008854546,0.000043857865,0.00017377532,0.0000021475248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008795016,0.005125662,0.028780742,0.004877428,0.000052616062,0.0015560446,0.007506727,0.0003839654,0.9225702,0.00028585788,0.00030237887,0.019763364],"study_design_scores_gemma":[0.059698783,0.013422785,0.18842307,0.00036423988,0.005420168,0.00016646266,0.006668233,0.018899022,0.6820076,0.006546701,0.015658934,0.0027239902],"about_ca_topic_score_codex":0.0004190701,"about_ca_topic_score_gemma":0.00001580758,"teacher_disagreement_score":0.24056257,"about_ca_system_score_codex":0.00004571783,"about_ca_system_score_gemma":0.0004088439,"threshold_uncertainty_score":0.73826486},"labels":[],"label_agreement":null},{"id":"W4290026710","doi":"10.1038/s41419-022-05117-9","title":"ErbB2/Her2-dependent downregulation of a cell death-promoting protein BLNK in breast cancer cells is required for 3D breast tumor growth","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; Dalhousie University","funders":"Canadian Institutes of Health Research; Government of Canada; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Anoikis; Downregulation and upregulation; Cancer research; Biology; Cancer cell; Breast cancer; Cancer","score_opus":0.00961269140939037,"score_gpt":0.22491895468801684,"score_spread":0.21530626327862648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4290026710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99449164,0.001086061,0.00017533686,0.00018185735,0.000051862076,0.0011634091,0.0024738503,0.0000130957515,0.00036289322],"genre_scores_gemma":[0.99749476,0.00004973109,0.00062531413,0.0002569435,0.000121204306,0.00069931906,0.0002377617,0.000036815927,0.0004781238],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985124,0.00010295664,0.00030688013,0.00052339357,0.00020108548,0.0003533044],"domain_scores_gemma":[0.99914145,0.000011448589,0.00018392889,0.00026673757,0.00008648407,0.0003099231],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024402249,0.00021981062,0.00020294542,0.000070778304,0.0001641716,0.000026416486,0.00016940472,0.00006155145,0.00018650497],"category_scores_gemma":[0.00001367664,0.000226709,0.0001134466,0.00008837398,0.000037151334,0.000010828822,0.0001939728,0.00009345251,0.0000016183287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011065269,0.00041392146,0.010220144,0.0006961838,0.000013515188,0.000016962655,0.00017475351,0.000051321276,0.9859228,0.000047779507,0.00017224785,0.0011638139],"study_design_scores_gemma":[0.0033871976,0.00032765334,0.017712172,0.00008622983,0.00009381943,0.000020760304,0.00016906351,0.0029795452,0.97328055,0.0007446119,0.0006705555,0.00052783993],"about_ca_topic_score_codex":0.00019350564,"about_ca_topic_score_gemma":0.000008279164,"teacher_disagreement_score":0.01264228,"about_ca_system_score_codex":0.000041145744,"about_ca_system_score_gemma":0.00026424535,"threshold_uncertainty_score":0.9244925},"labels":[],"label_agreement":null},{"id":"W4291019683","doi":"10.1038/s41419-022-05126-8","title":"Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"KEAP1; Head and neck squamous-cell carcinoma; Cancer research; Biology; Gene silencing; Cancer; Cancer stem cell; Genetics; Head and neck cancer; Transcription factor; Gene","score_opus":0.013767883404623716,"score_gpt":0.2200180178951878,"score_spread":0.2062501344905641,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291019683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99498314,0.003878603,0.00030785255,0.00005553391,0.000020622008,0.0001684341,0.00013621466,0.0000016486395,0.0004479514],"genre_scores_gemma":[0.9991145,0.000111890375,0.00025547933,0.00017005023,0.000026067864,0.000025698699,0.000123353,0.000009089172,0.00016384937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993918,0.00003642168,0.00015418888,0.00024431807,0.00007014177,0.00010316388],"domain_scores_gemma":[0.9996535,0.000017561733,0.00007418384,0.00013012334,0.000037114303,0.000087501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000031463383,0.000095868025,0.00010997448,0.000025415186,0.0000673724,0.0000072135854,0.000039919527,0.000031375836,0.000014359686],"category_scores_gemma":[0.000014885645,0.000104657316,0.00002646191,0.00003785107,0.000081407365,0.000005138372,0.000056536654,0.000047238704,7.556884e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005991463,0.00020856736,0.11218399,0.00022916186,0.0000059381655,0.0000014556007,0.00026505694,0.00013514397,0.8860636,0.00010112152,0.000093488045,0.00011337223],"study_design_scores_gemma":[0.0023517057,0.00023409475,0.3124048,0.000009119753,0.000025813591,0.0000011886797,0.00028598565,0.00016153052,0.6823049,0.0010347392,0.0009998371,0.00018628208],"about_ca_topic_score_codex":0.000027360935,"about_ca_topic_score_gemma":0.0000100648485,"teacher_disagreement_score":0.20375866,"about_ca_system_score_codex":0.000009258878,"about_ca_system_score_gemma":0.00009947668,"threshold_uncertainty_score":0.42678016},"labels":[],"label_agreement":null},{"id":"W4291825011","doi":"10.1038/s41419-022-05146-4","title":"EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu","keywords":"Epigenetics; Epigenome; Biology; CRISPR; Chromatin; Cancer; Triple-negative breast cancer; Computational biology; Cancer cell; Cancer research; Genetics; DNA methylation; Gene; Breast cancer; Gene expression","score_opus":0.018693686496371893,"score_gpt":0.30313275053716016,"score_spread":0.2844390640407883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291825011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9505894,0.013067193,0.03515538,0.00017470332,0.00020408769,0.0003489133,0.00025764867,0.00003381352,0.00016884645],"genre_scores_gemma":[0.99683845,0.00016204061,0.001397883,0.00048971176,0.00017524183,0.00030942747,0.0001897443,0.00003926856,0.00039826098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986843,0.00004474053,0.00021406797,0.00048460023,0.00020576619,0.00036652925],"domain_scores_gemma":[0.99892235,0.00002321531,0.00004124652,0.0003898438,0.000036472782,0.0005868801],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001348147,0.00021718457,0.00016026036,0.00008279739,0.00033368965,0.000060312315,0.00018745865,0.00004138132,0.00024193455],"category_scores_gemma":[0.000042922344,0.00023698981,0.000104438244,0.00011361488,0.00003493556,0.0000043608284,0.00020159868,0.00010561441,0.000005300579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011517539,0.0003867567,0.030453626,0.00056399807,0.00007822587,0.000111689515,0.00059001875,0.1605841,0.76963264,0.000102584665,0.015194783,0.021149829],"study_design_scores_gemma":[0.006224689,0.0012888529,0.14727534,0.000113120936,0.0002836692,0.000016883689,0.0015961917,0.014490474,0.57206136,0.0005668888,0.25348863,0.0025939029],"about_ca_topic_score_codex":0.00005846797,"about_ca_topic_score_gemma":0.000010565338,"teacher_disagreement_score":0.23829384,"about_ca_system_score_codex":0.000026483263,"about_ca_system_score_gemma":0.00012654177,"threshold_uncertainty_score":0.9664164},"labels":[],"label_agreement":null},{"id":"W4293325628","doi":"10.1038/s41419-022-05190-0","title":"Low quantity and quality of anti-spike humoral response is linked to CD4 T-cell apoptosis in COVID-19 patients","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"European Regional Development Fund; AbbVie Canada; Fundação para a Ciência e a Tecnologia; Universidade do Minho; Agence Nationale de la Recherche","keywords":"Avidity; Immunology; Antibody; Apoptosis; Humoral immunity; Immune system; Biology; Programmed cell death; T cell","score_opus":0.06462468191005967,"score_gpt":0.36786014209677553,"score_spread":0.3032354601867159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293325628","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977035,0.0006332917,0.00002297672,0.00043381107,0.00005114192,0.0006932567,0.00027708893,0.000023829181,0.00016108638],"genre_scores_gemma":[0.9635146,0.000019001212,0.000041886626,0.036235213,0.000017227596,0.00006429701,0.000024961888,0.000016872367,0.00006593627],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979152,0.00037263695,0.00035549916,0.00048008322,0.0005367141,0.00033985102],"domain_scores_gemma":[0.9985202,0.00025430878,0.00007918006,0.0004013281,0.00008010982,0.0006648961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079790805,0.00016955251,0.00036608265,0.0002974299,0.00016420371,0.000028929982,0.00013109067,0.000049981918,0.000060552342],"category_scores_gemma":[0.0009985216,0.00016562828,0.00009092819,0.0003815097,0.00009376181,0.000066659864,0.00029141968,0.00020674444,0.000009335465],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01425769,0.001471169,0.947553,0.00093591696,0.000007849438,0.000055456152,0.0008664701,0.0000021812452,0.034022838,0.000018189314,0.0005795371,0.00022974006],"study_design_scores_gemma":[0.008426594,0.0008521008,0.9681525,0.000038854232,0.000058230777,6.402551e-7,0.0005494412,0.00012722483,0.016039653,0.00016327371,0.0053204456,0.0002710128],"about_ca_topic_score_codex":0.0008418887,"about_ca_topic_score_gemma":0.000019574802,"teacher_disagreement_score":0.0358014,"about_ca_system_score_codex":0.00012891534,"about_ca_system_score_gemma":0.0007545038,"threshold_uncertainty_score":0.67541254},"labels":[],"label_agreement":null},{"id":"W4293546841","doi":"10.1038/s41419-022-05185-x","title":"Inhibitory effect of the novel tyrosine kinase inhibitor DCC-2036 on triple-negative breast cancer stem cells through AXL-KLF5 positive feedback loop","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Natural Science Foundation of China; Health Commission of Hunan Province","keywords":"Triple-negative breast cancer; Cancer research; Breast cancer; AXL receptor tyrosine kinase; Receptor tyrosine kinase; Cancer stem cell; Tyrosine kinase; Tyrosine-kinase inhibitor; Downregulation and upregulation; Cancer; Kinase; Biology; Chemistry; Medicine; Signal transduction; Internal medicine; Cell biology; JAK-STAT signaling pathway; Biochemistry","score_opus":0.008836092001630776,"score_gpt":0.22132300342823305,"score_spread":0.21248691142660228,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293546841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877127,0.0071811033,0.000011719823,0.00030722175,0.0011669407,0.00082199957,0.0023530999,0.000026127902,0.00041910933],"genre_scores_gemma":[0.99607223,0.00009880283,0.0000029332973,0.00037129282,0.00007135832,0.00012561897,0.000099726305,0.00002639183,0.0031316325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984116,0.0004427439,0.00029953205,0.00041723988,0.000109575056,0.00031932074],"domain_scores_gemma":[0.999066,0.00019380148,0.0002443888,0.00034101345,0.00006803274,0.0000867549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001553864,0.0002928011,0.00036114684,0.00006210342,0.00054368365,0.000017392207,0.00018598889,0.00009583227,0.00024429493],"category_scores_gemma":[0.000017955814,0.00020769873,0.00021054244,0.00020239856,0.00028587566,0.00012524868,0.00024309474,0.000310351,0.00002057016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0066999155,0.0011637144,0.0050929477,0.00019100297,0.00015886493,0.000008459204,0.0007168528,0.00020637407,0.9763921,0.00032886042,0.005914033,0.0031268564],"study_design_scores_gemma":[0.0075883395,0.0006304433,0.060970716,0.00015084476,0.00031676036,0.00001040454,0.00023403234,0.000050153467,0.92842335,0.000059759917,0.0012497865,0.00031540246],"about_ca_topic_score_codex":0.00020617094,"about_ca_topic_score_gemma":0.0000027057092,"teacher_disagreement_score":0.05587777,"about_ca_system_score_codex":0.00014089387,"about_ca_system_score_gemma":0.0001823848,"threshold_uncertainty_score":0.84697086},"labels":[],"label_agreement":null},{"id":"W4295182896","doi":"10.1038/s41419-022-05128-6","title":"Deubiquitinase OTUD5 modulates mTORC1 signaling to promote bladder cancer progression","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"National Natural Science Foundation of China","keywords":"PI3K/AKT/mTOR pathway; Deubiquitinating enzyme; mTORC1; Cancer research; Ubiquitin ligase; Regulator; Cancer; Biology; Signal transduction; Bladder cancer; Tumor progression; RPTOR; Ubiquitin; Cell biology; Biochemistry; Genetics; Gene","score_opus":0.012755941629793266,"score_gpt":0.261907678777783,"score_spread":0.24915173714798972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295182896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99272996,0.0055677635,0.00015261042,0.00021496433,0.00007974283,0.000497565,0.00016610099,0.000025618463,0.00056567695],"genre_scores_gemma":[0.99636275,0.00007016019,0.00036139565,0.0012960789,0.00020000053,0.00048587794,0.0001608769,0.000027545999,0.0010353333],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989389,0.000060795926,0.0001254178,0.00042468088,0.00016182012,0.0002883676],"domain_scores_gemma":[0.99908376,0.0000045082,0.000045716228,0.00022294659,0.00003832517,0.0006047311],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011527007,0.00015974765,0.00010023037,0.00003715354,0.00032849255,0.000036945865,0.00012964118,0.000036434387,0.000233656],"category_scores_gemma":[0.000034351182,0.00015205813,0.00006156231,0.00007054921,0.000022942208,0.000003824034,0.0003060475,0.00008243291,0.0000065506724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007213927,0.0003102597,0.013812393,0.00015770816,0.00003106563,0.00008229682,0.00025224456,0.0009930739,0.96958774,0.000092123766,0.0030598633,0.010899841],"study_design_scores_gemma":[0.0012643255,0.00081913563,0.0023580051,0.000049570182,0.000100985046,0.000008604925,0.00016589399,0.00080628425,0.86869836,0.0006631784,0.1243633,0.00070238445],"about_ca_topic_score_codex":0.000014279343,"about_ca_topic_score_gemma":0.0000015195311,"teacher_disagreement_score":0.12130344,"about_ca_system_score_codex":0.00001548459,"about_ca_system_score_gemma":0.00014789922,"threshold_uncertainty_score":0.62007505},"labels":[],"label_agreement":null},{"id":"W4304208613","doi":"10.1038/s41419-022-05290-x","title":"Caspase-1 inhibition improves cognition without significantly altering amyloid and inflammation in aged Alzheimer disease mice","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; Jewish General Hospital","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Jewish General Hospital; Fondation de l'Hôpital général juif; Government of Canada","keywords":"Microglia; Inflammation; Inflammasome; Hippocampal formation; Alzheimer's disease; Hippocampus; Cognitive decline; Neuroscience; Synaptophysin; Medicine; Neuroinflammation; Immunology; Endocrinology; Internal medicine; Psychology; Disease; Dementia; Immunohistochemistry","score_opus":0.02300041958746901,"score_gpt":0.2722274467274009,"score_spread":0.2492270271399319,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4304208613","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875168,0.010514141,0.000013986971,0.00026041505,0.000030048763,0.0010595291,0.00024041072,0.000051231018,0.0003134191],"genre_scores_gemma":[0.99783355,0.0003242616,0.000047949405,0.0002448309,0.000072273484,0.0004012074,0.0010113142,0.00002789405,0.000036746773],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99856913,0.00012352772,0.00021978025,0.00042691143,0.00033848034,0.00032218118],"domain_scores_gemma":[0.99826574,0.00004406367,0.00006915751,0.00017187578,0.000043164586,0.001405977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013003332,0.000199803,0.00019082637,0.00020031766,0.00028578224,0.000054535598,0.000030141913,0.000025510257,0.000091708964],"category_scores_gemma":[0.00005657593,0.00019481966,0.00005816228,0.00014157155,0.000072826755,0.00022136453,0.00009637288,0.00016747222,0.0000100659045],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.029256638,0.004063717,0.86274254,0.001967843,0.0017114618,0.010876128,0.0012077313,0.00009844142,0.06902923,0.00023665423,0.0005030632,0.018306578],"study_design_scores_gemma":[0.009043664,0.00038885634,0.9786721,0.0001397423,0.0023434798,0.000022976406,0.0005425167,0.0032858162,0.0034910245,0.0015853468,0.00006923396,0.0004152598],"about_ca_topic_score_codex":0.0000693822,"about_ca_topic_score_gemma":0.000005876316,"teacher_disagreement_score":0.11592957,"about_ca_system_score_codex":0.000059812777,"about_ca_system_score_gemma":0.00026151107,"threshold_uncertainty_score":0.7944515},"labels":[],"label_agreement":null},{"id":"W4305070936","doi":"10.1038/s41419-022-05315-5","title":"c-Mpl-del, a c-Mpl alternative splicing isoform, promotes AMKL progression and chemoresistance","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; University of Toronto; St. Michael's Hospital","funders":"University of Toronto; Canadian Institutes of Health Research; Sun Yat-sen University; National Natural Science Foundation of China; Government of Canada","keywords":"Acute megakaryoblastic leukemia; Cancer research; Downregulation and upregulation; Biology; Gene knockdown; Myeloid leukemia; Cell growth; Thrombopoietin; Leukemia; PI3K/AKT/mTOR pathway; Apoptosis; Signal transduction; Haematopoiesis; Cell biology; Immunology; Stem cell; Gene; Genetics","score_opus":0.015958753326727877,"score_gpt":0.2905445603696919,"score_spread":0.27458580704296404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4305070936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99108917,0.004396497,0.000056825615,0.0008501013,0.000037459467,0.0007945834,0.00006042004,0.0000575213,0.002657453],"genre_scores_gemma":[0.99545825,0.0002398052,0.00062401383,0.00057527923,0.00010653076,0.00018955847,0.000081570994,0.00002993435,0.0026950329],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99856925,0.000042575044,0.00016279424,0.0004379683,0.0004189848,0.0003684297],"domain_scores_gemma":[0.9987148,0.00004789929,0.00006558927,0.00025626115,0.00005969353,0.0008557267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017028172,0.00017507536,0.00021571045,0.00010065746,0.0003747794,0.000041192186,0.00009996177,0.000028231258,0.00012788097],"category_scores_gemma":[0.000111165056,0.00014384494,0.000047801437,0.00015313228,0.000103392005,0.00009380917,0.00032466173,0.00028777748,0.000007402269],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014435474,0.0022990822,0.85044837,0.0044822884,0.00020590056,0.0057335612,0.0045396797,0.000021704698,0.047660794,0.0020049121,0.0144312885,0.05373692],"study_design_scores_gemma":[0.032187603,0.0039909976,0.8184622,0.0010188541,0.0010477484,0.00042779325,0.003687688,0.05774568,0.032052014,0.009198334,0.03810609,0.002074978],"about_ca_topic_score_codex":0.000047991427,"about_ca_topic_score_gemma":0.0000014832748,"teacher_disagreement_score":0.057723977,"about_ca_system_score_codex":0.00011261055,"about_ca_system_score_gemma":0.0003135756,"threshold_uncertainty_score":0.58658266},"labels":[],"label_agreement":null},{"id":"W4317679859","doi":"10.1038/s41419-022-05548-4","title":"Longitudinal efficacy and toxicity of SARS-CoV-2 vaccination in cancer patients treated with immunotherapy","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"University Health Network","keywords":"Toxicity; Immunotherapy; Medicine; Oncology; Cancer immunotherapy; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Vaccination; Immunology; Cancer; Internal medicine; Coronavirus disease 2019 (COVID-19); Cancer research; Virology; Disease; Infectious disease (medical specialty)","score_opus":0.04167334633966334,"score_gpt":0.34464258000965986,"score_spread":0.3029692336699965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317679859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99816495,0.00097391586,0.000004452458,0.000054525855,0.000011826835,0.00039745486,0.00002267894,0.000026357315,0.0003438215],"genre_scores_gemma":[0.998661,0.00012056098,0.0000052537434,0.0011070344,0.000015655072,0.000036413643,0.000016159276,0.000013232177,0.000024711379],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992415,0.000024691795,0.0001304091,0.00022510557,0.00019054337,0.000187765],"domain_scores_gemma":[0.9996478,0.000043734482,0.00003554532,0.00012829264,0.000078257326,0.00006637038],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000067019304,0.000108077846,0.00017472135,0.00017567984,0.00003757136,0.000013843301,0.00003640307,0.0000359207,0.0000054176257],"category_scores_gemma":[0.000043028012,0.00008150463,0.000023694287,0.0003196216,0.000033546334,0.000058343463,0.000022591195,0.00006732899,0.000003422137],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026383835,0.0005189767,0.9558177,0.00020488894,0.000018256662,0.000056095065,0.00011732384,5.1976343e-7,0.03622831,0.0000067578785,0.0000756619,0.0043171123],"study_design_scores_gemma":[0.0062111663,0.00035917165,0.910753,0.000069675036,0.000036889545,4.6968853e-7,0.000010919625,0.00036492414,0.08187888,0.00003358053,0.00019973805,0.000081579536],"about_ca_topic_score_codex":0.0003618691,"about_ca_topic_score_gemma":0.000037214486,"teacher_disagreement_score":0.045650568,"about_ca_system_score_codex":0.000039908806,"about_ca_system_score_gemma":0.00012801884,"threshold_uncertainty_score":0.33236623},"labels":[],"label_agreement":null},{"id":"W4319320751","doi":"10.1038/s41419-023-05567-9","title":"Regulation of immunological tolerance by the p53-inhibitor iASPP","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; Rhodes Scholarships; Ludwig Institute for Cancer Research; Wellcome Trust; National Institute of General Medical Sciences; Wellcome; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Biology; Autoimmunity; Immune tolerance; Cancer research; Immune system; Immunology; Regulator; Peripheral tolerance; Apoptosis; Gene","score_opus":0.014108909651528391,"score_gpt":0.24683372990694816,"score_spread":0.23272482025541977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319320751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881317,0.009269771,0.000016046164,0.0012166717,0.000085588836,0.00017900403,0.000026573634,0.00003671666,0.0010378968],"genre_scores_gemma":[0.9956848,0.00074589875,0.000011830875,0.00041855534,0.0000554863,0.000012978078,0.000049927774,0.000005271268,0.0030152786],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995572,0.000018712472,0.00010886676,0.00011327622,0.00009948371,0.00010244318],"domain_scores_gemma":[0.99965954,0.000034826004,0.000032865486,0.00015562859,0.000020454878,0.000096667616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007547954,0.00006116161,0.00008895728,0.000020366026,0.000057286223,0.0000075327066,0.00003447392,0.00003007941,0.000092240785],"category_scores_gemma":[0.000027319045,0.000036833724,0.000059254373,0.00011818893,0.00008027233,0.000022529613,0.000015164703,0.00003971876,0.000011506551],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013050405,0.0004334619,0.06348151,0.00044492033,0.00008762795,0.00004506493,0.00045980536,0.000010687864,0.7408038,0.00034566692,0.111071624,0.06976547],"study_design_scores_gemma":[0.0027985226,0.00020475332,0.94555837,0.00007677956,0.00009024455,0.000003584898,0.00014471485,0.00065162935,0.018661268,0.00048533024,0.031210966,0.00011383407],"about_ca_topic_score_codex":0.000014639867,"about_ca_topic_score_gemma":2.4360358e-7,"teacher_disagreement_score":0.88207686,"about_ca_system_score_codex":0.000009399672,"about_ca_system_score_gemma":0.000041487667,"threshold_uncertainty_score":0.15020357},"labels":[],"label_agreement":null},{"id":"W4320482471","doi":"10.1038/s41419-023-05626-1","title":"Dynamic differentiation of F4/80+ tumor-associated macrophage and its role in tumor vascularization in a syngeneic mouse model of colorectal liver metastasis","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Science, Technology and Innovation Commission of Shenzhen Municipality; National Natural Science Foundation of China; Southern University of Science and Technology; York University","keywords":"Metastasis; Colorectal cancer; Cancer research; Macrophage; Biology; Pathology; Medicine; Cancer; In vitro; Genetics","score_opus":0.007676246151505199,"score_gpt":0.20832054020067106,"score_spread":0.20064429404916587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320482471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895079,0.009815103,0.00003935705,0.0000053468993,0.000051359024,0.00028189138,0.0002534698,0.000019343912,0.000026191336],"genre_scores_gemma":[0.998578,0.00076935533,0.000016757751,0.00001630834,9.1815434e-7,0.000033848304,0.0002976753,0.000015025047,0.00027212166],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991209,0.00013927431,0.00026524893,0.00022732481,0.000041046434,0.00020622289],"domain_scores_gemma":[0.99963576,0.00005155658,0.00012348114,0.000108334476,0.00004224124,0.000038634098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014048582,0.00012748477,0.0002616705,0.00022009779,0.000035662844,0.0000052147566,0.00007011177,0.00007509523,0.000027676842],"category_scores_gemma":[0.00009487823,0.00012823199,0.00005123209,0.00020951514,0.000054594828,0.000067971334,0.00008326546,0.00009941665,0.0000069662574],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051041495,0.00043456038,0.0681527,0.0003561215,0.00007201347,0.000019699082,0.00067273783,0.002858563,0.9265157,0.000085919375,0.000012118958,0.0003094685],"study_design_scores_gemma":[0.004703409,0.00011199904,0.5135411,0.00009306041,0.000253948,0.0000014334385,0.00019340825,0.22636661,0.2539439,0.0005106443,0.0000025150289,0.0002780026],"about_ca_topic_score_codex":0.00008408217,"about_ca_topic_score_gemma":0.000050674338,"teacher_disagreement_score":0.6725718,"about_ca_system_score_codex":0.000048191156,"about_ca_system_score_gemma":0.000079802034,"threshold_uncertainty_score":0.5229149},"labels":[],"label_agreement":null},{"id":"W4321243260","doi":"10.1038/s41419-023-05650-1","title":"Early postnatal defects in neurogenesis in the 3xTg mouse model of Alzheimer’s disease","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Neurogenesis; Disease; Neuroscience; Alzheimer's disease; Biology; Medicine; Pathology","score_opus":0.05340735716556935,"score_gpt":0.25365188769081537,"score_spread":0.20024453052524602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321243260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998881,0.00018709614,0.00001591892,0.0001133547,0.000060797298,0.0003893686,0.00021683727,0.00005144355,0.00008419162],"genre_scores_gemma":[0.9983688,0.0002716084,0.000005135874,0.0011930843,0.000013834477,0.000051198185,0.000005388886,0.00003057492,0.000060397637],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828804,0.00022217433,0.00024814846,0.00052359066,0.00033964988,0.00037839852],"domain_scores_gemma":[0.9988306,0.00026131416,0.000060845614,0.0003648853,0.000012859345,0.00046946498],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012500907,0.0001968951,0.00017407311,0.00023255251,0.00008793322,0.000046888585,0.00028031933,0.000028752213,0.000004773465],"category_scores_gemma":[0.00037185245,0.00015754858,0.00009501425,0.0004800455,0.00006506965,0.00012985832,0.00013700518,0.000108949476,0.000027674476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006504776,0.0006934263,0.025197437,0.00014206031,0.00000199722,0.0027257714,0.000290592,0.006165589,0.959587,0.0043413527,0.00008396599,0.000120376244],"study_design_scores_gemma":[0.0014834326,0.00014314354,0.2569806,0.000027191412,0.00012254552,0.0000047880008,0.000043238964,0.082087934,0.65742177,0.0012739836,0.000013401401,0.00039799217],"about_ca_topic_score_codex":0.000015323047,"about_ca_topic_score_gemma":0.0000021268527,"teacher_disagreement_score":0.3021652,"about_ca_system_score_codex":0.000004869747,"about_ca_system_score_gemma":0.00010339752,"threshold_uncertainty_score":0.64246446},"labels":[],"label_agreement":null},{"id":"W4322719981","doi":"10.1038/s41419-023-05692-5","title":"Supplementation with α-ketoglutarate improved the efficacy of anti-PD1 melanoma treatment through epigenetic modulation of PD-L1","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health","funders":"Project 211; Higher Education Discipline Innovation Project","keywords":"Melanoma; STAT1; Epigenetics; Cancer research; Immunotherapy; Medicine; Downregulation and upregulation; Immune system; Pharmacology; Immunology; Internal medicine; Biology; Interferon; Biochemistry; Gene","score_opus":0.015178100767493157,"score_gpt":0.25428041054278383,"score_spread":0.23910230977529068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322719981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962934,0.0024528438,0.00014880692,0.00011154803,0.00014658837,0.00045413643,0.00011417743,0.00001992989,0.00025853774],"genre_scores_gemma":[0.99745154,0.0007045549,0.000058082285,0.000028245908,0.000011770226,0.000038702026,0.000422653,0.000012055554,0.0012723927],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993266,0.00007831905,0.00020290416,0.000186683,0.000030229707,0.00017530167],"domain_scores_gemma":[0.99945104,0.000103251456,0.00012794255,0.00025412228,0.000039013823,0.000024644514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057238198,0.00012407269,0.00016718685,0.000037349277,0.00009443566,0.000005449161,0.00007391637,0.00004510899,0.00013897032],"category_scores_gemma":[0.000012284607,0.00007161543,0.0000528153,0.000114520386,0.00014161867,0.000041827287,0.000029407467,0.000036609898,0.00002329504],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028484461,0.0005605301,0.097860485,0.00023467556,0.00032451635,0.000009584312,0.0027671352,0.0016455664,0.8831723,0.0002873087,0.00054601824,0.009743437],"study_design_scores_gemma":[0.005467412,0.00063311146,0.61386204,0.000029194602,0.0003389481,0.000001720318,0.00031850964,0.00038406902,0.37687582,0.00034625552,0.0015827157,0.00016020806],"about_ca_topic_score_codex":0.00015489633,"about_ca_topic_score_gemma":0.0000057976827,"teacher_disagreement_score":0.5160016,"about_ca_system_score_codex":0.000019943267,"about_ca_system_score_gemma":0.00009214391,"threshold_uncertainty_score":0.29203925},"labels":[],"label_agreement":null},{"id":"W4322754763","doi":"10.1038/s41419-023-05672-9","title":"Alpha-synuclein in Parkinson’s disease and other synucleinopathies: from overt neurodegeneration back to early synaptic dysfunction","year":2023,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":739,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministero dell’Istruzione, dell’Università e della Ricerca; School of Medicine, New York University; Ministero della Salute; York University","keywords":"Synucleinopathies; Neurodegeneration; Neuroscience; Parkinson's disease; Alpha-synuclein; Dementia; Dementia with Lewy bodies; Disease; Medicine; Lewy body; Biology; Pathology","score_opus":0.04231446577368977,"score_gpt":0.2772766453204531,"score_spread":0.23496217954676332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322754763","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.112686105,0.88312256,0.000038151076,0.00006434725,0.00027088108,0.0021039136,0.0014434791,0.000115704745,0.00015486084],"genre_scores_gemma":[0.034066807,0.96200204,0.0001208621,0.0009093274,0.0003089533,0.0005743457,0.00074030063,0.0002128845,0.0010644925],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972279,0.00017697168,0.00053954514,0.0012453324,0.00034831426,0.0004619227],"domain_scores_gemma":[0.99652654,0.00010444794,0.00016007568,0.00060720864,0.00003496241,0.0025667434],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010961648,0.0006806315,0.0011752537,0.0003967084,0.00012175084,0.00014687324,0.00010070598,0.00018781783,0.00015656889],"category_scores_gemma":[0.00014826607,0.00057872955,0.0002884062,0.0003057056,0.000040169758,0.00012575787,0.00012903409,0.00021519542,0.00064409734],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007336895,0.005421567,0.11374149,0.08578087,0.0025210732,0.018386543,0.00062073313,0.000025882353,0.00008336298,0.00090599107,0.0068808026,0.7582948],"study_design_scores_gemma":[0.0030542265,0.00038479356,0.06800904,0.010321355,0.0083157,0.000008110029,0.00002186285,0.00053788413,0.0000027347594,0.0005491958,0.90780306,0.0009920121],"about_ca_topic_score_codex":0.000267203,"about_ca_topic_score_gemma":0.000020869702,"teacher_disagreement_score":0.9009223,"about_ca_system_score_codex":0.00015051979,"about_ca_system_score_gemma":0.00038843736,"threshold_uncertainty_score":0.9996664},"labels":[],"label_agreement":null},{"id":"W4327566649","doi":"10.1038/s41419-023-05720-4","title":"GEMC1 and MCIDAS interactions with SWI/SNF complexes regulate the multiciliated cell-specific transcriptional program","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Canada Research Chairs; University Health Network","funders":"National Medical Research Council; National Institute of General Medical Sciences; Medical Research Council; Associazione Italiana per la Ricerca sul Cancro; Ministerio de Ciencia, Innovación y Universidades; National Heart, Lung, and Blood Institute; Institute for Research in Biomedicine; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Motile cilium; Biology; Transcription factor; Cell biology; Ciliogenesis; SWI/SNF; Cilium; Transcriptional regulation; Transcription (linguistics); Regulation of gene expression; ARID1A; Cell fate determination; Cellular differentiation; Gene; Genetics; Mutation; Chromatin remodeling","score_opus":0.017455175796884992,"score_gpt":0.2562945606603468,"score_spread":0.2388393848634618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327566649","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949548,0.0036613347,0.0003015876,0.0002335507,0.000049391663,0.00022437893,0.000057569487,0.000045419067,0.00047194],"genre_scores_gemma":[0.9972152,0.00076156994,0.00023154136,0.00012593712,0.000078333076,0.000055437904,0.00027330278,0.000013921348,0.0012447194],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994091,0.000023128863,0.000091858,0.00024386989,0.000078580415,0.00015351069],"domain_scores_gemma":[0.9995754,0.00001075453,0.000025670473,0.00016512784,0.000038979648,0.00018411365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004100178,0.0001102856,0.00006776561,0.000019897789,0.0001769484,0.00005202968,0.000053434058,0.000028524284,0.000016923694],"category_scores_gemma":[0.0000051299126,0.000074719705,0.000038743583,0.00006315634,0.00009001143,0.000003939957,0.000025748615,0.000053229363,0.0000060586294],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020878417,0.0008147445,0.01563008,0.0005160479,0.00013756717,0.000059088252,0.0007586004,0.003610777,0.9175364,0.0003763532,0.035146903,0.023325603],"study_design_scores_gemma":[0.0101695275,0.0011598447,0.38649336,0.00024304369,0.00056479336,0.00005948025,0.0017805157,0.095364034,0.056583267,0.0020714086,0.44376507,0.0017456574],"about_ca_topic_score_codex":0.000014726517,"about_ca_topic_score_gemma":0.0000087468225,"teacher_disagreement_score":0.86095315,"about_ca_system_score_codex":0.0000045578927,"about_ca_system_score_gemma":0.00004337681,"threshold_uncertainty_score":0.3046981},"labels":[],"label_agreement":null},{"id":"W4362471442","doi":"10.1038/s41419-023-05725-z","title":"USP18 is an essential regulator of muscle cell differentiation and maturation","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Engineering and Physical Sciences Research Council; Chinese Academy of Medical Sciences; AFM-Téléthon; Pfizer","keywords":"ISG15; Biology; Transcriptome; Myogenesis; Cell biology; Cellular differentiation; Regulator; Gene expression; Myocyte; Regulation of gene expression; Gene; Ubiquitin; Genetics","score_opus":0.01035911795247767,"score_gpt":0.2267825730139029,"score_spread":0.2164234550614252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362471442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986696,0.0006029386,0.00014601524,0.000039505987,0.000045407425,0.00011864694,0.00008096145,0.0000123970585,0.00028451835],"genre_scores_gemma":[0.99855006,0.00024959326,0.0000664367,0.000077024946,0.00009337461,0.000009200936,0.00043638167,0.000009162951,0.0005087697],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952126,0.000026029484,0.00008742357,0.00020046088,0.00006429954,0.00010051494],"domain_scores_gemma":[0.9995796,0.0000034978475,0.000041389452,0.00014625074,0.000026790049,0.00020244093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004220771,0.000076285825,0.00006102615,0.00002750651,0.00005649525,0.000022016204,0.00003550264,0.00005387886,0.000023440956],"category_scores_gemma":[0.000012229694,0.00007238814,0.000027993545,0.000037103357,0.000026840751,0.000006389273,0.00004319337,0.000020703206,0.0000035507007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001329167,0.00006182539,0.006448669,0.00016970954,0.0000041732346,0.000002018416,0.000115004754,0.0000029666792,0.9911355,0.00007207516,0.0006939494,0.0011612094],"study_design_scores_gemma":[0.00066466874,0.00012531756,0.1897169,0.0000093863255,0.000043715525,4.7810465e-7,0.00007240394,0.001415555,0.80597085,0.00073196896,0.0010961058,0.00015264835],"about_ca_topic_score_codex":0.0000056270846,"about_ca_topic_score_gemma":0.0000011815838,"teacher_disagreement_score":0.18516465,"about_ca_system_score_codex":0.0000014085199,"about_ca_system_score_gemma":0.000029173347,"threshold_uncertainty_score":0.29519024},"labels":[],"label_agreement":null},{"id":"W4362604781","doi":"10.1038/s41419-023-05665-8","title":"The MEF2A transcription factor interactome in cardiomyocytes","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; Sanofi (Canada); University of Toronto; Seneca Polytechnic; York University","funders":"CIHR Skin Research Training Centre; Mitacs; Canadian Institutes of Health Research; York University; Government of Canada; Sanofi","keywords":"Interactome; Transcription factor; Cell biology; Computational biology; Chemistry; Biology; Genetics; Gene","score_opus":0.022296903466788056,"score_gpt":0.2693610770917035,"score_spread":0.24706417362491542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362604781","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875263,0.008064194,0.000011208361,0.0007808193,0.00022702443,0.00022423838,0.000031363048,0.00006640897,0.0030684692],"genre_scores_gemma":[0.99538803,0.0029586516,0.000003851528,0.00017625521,0.00010239518,0.000039925017,0.000020889749,0.000008532955,0.0013014781],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9994112,0.000025207366,0.00010801197,0.00015426514,0.0001140404,0.00018727459],"domain_scores_gemma":[0.99950916,0.00008096539,0.000013108662,0.00014128469,0.000022983097,0.000232503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008787373,0.00008896264,0.00015212671,0.000070756374,0.000106123975,0.000026895854,0.00002932436,0.00002172792,0.000007788641],"category_scores_gemma":[0.00008787694,0.00005926093,0.00010392048,0.00014817962,0.000043395943,0.000045016623,0.00002539185,0.00007478029,0.00003135283],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037281718,0.00026478537,0.88627386,0.0010319176,0.00021762945,0.0021137025,0.0057676835,0.000017753928,0.018390086,0.001063028,0.016077481,0.0650539],"study_design_scores_gemma":[0.0011647587,0.00004499066,0.9625649,0.000051017967,0.0001161142,0.0000050788485,0.0007534117,0.000115956056,0.00035929473,0.00040192905,0.034322996,0.00009957308],"about_ca_topic_score_codex":0.000018229619,"about_ca_topic_score_gemma":0.0000047929507,"teacher_disagreement_score":0.07629102,"about_ca_system_score_codex":0.000019839737,"about_ca_system_score_gemma":0.00004109264,"threshold_uncertainty_score":0.24165905},"labels":[],"label_agreement":null},{"id":"W4362700442","doi":"10.1038/s41419-022-05484-3","title":"Autophagy deficiency exacerbates iron overload induced reactive oxygen species production and apoptotic cell death in skeletal muscle cells","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; York University; International Development Research Centre; Government of Canada","keywords":"Autophagy; Reactive oxygen species; Cell biology; Apoptosis; Programmed cell death; Skeletal muscle; Oxygen; Mitochondrion; Myocyte; Biology; Chemistry; Biochemistry; Endocrinology","score_opus":0.01858606746596604,"score_gpt":0.24941774680130543,"score_spread":0.23083167933533938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362700442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99295527,0.0034445669,0.0000042774027,0.00015996849,0.00020826099,0.00067131035,0.000033812154,0.00014051262,0.002381996],"genre_scores_gemma":[0.99518496,0.0014337408,0.000041387433,0.00018610015,0.00016911162,0.00005058292,0.0001048139,0.000036089423,0.0027931964],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99835247,0.000058692345,0.00025110738,0.00062732736,0.00026400347,0.00044640916],"domain_scores_gemma":[0.9988265,0.00005849126,0.00008097914,0.00033177587,0.00004364176,0.00065859046],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014095758,0.00028006115,0.00029321888,0.00023879803,0.0001579226,0.00004458695,0.00007026601,0.000096009324,0.00007149318],"category_scores_gemma":[0.0000903525,0.0002514001,0.00008468523,0.00032674952,0.000080496204,0.00019059354,0.000067761626,0.0001811651,0.000076144024],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011715973,0.0029117805,0.06301018,0.0023090085,0.000051437186,0.0015023329,0.0035676982,0.00011247712,0.91764355,0.0006233756,0.0015919366,0.0055046263],"study_design_scores_gemma":[0.0019202341,0.00027988723,0.93730974,0.000096958276,0.00019630036,0.000004356937,0.0006280229,0.00061975804,0.05713565,0.0010312897,0.0004316569,0.00034614257],"about_ca_topic_score_codex":0.000051510462,"about_ca_topic_score_gemma":0.000002746438,"teacher_disagreement_score":0.8742996,"about_ca_system_score_codex":0.00006983606,"about_ca_system_score_gemma":0.000189013,"threshold_uncertainty_score":0.9999938},"labels":[],"label_agreement":null},{"id":"W4376114444","doi":"10.1038/s41419-023-05818-9","title":"Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency in prostate cancer cell lines","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Blood properties and coagulation","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Debreceni Egyetem; Trent University; Nottingham Trent University","keywords":"Tissue transglutaminase; Prostate cancer; Mucin; Androgen; Prostate; Cancer research; Protein expression; Cancer; Biology; Internal medicine; Chemistry; Medicine; Endocrinology; Enzyme; Biochemistry; Hormone","score_opus":0.01667458590055101,"score_gpt":0.25043541970854966,"score_spread":0.23376083380799864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376114444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9810309,0.017798658,0.0000014931494,0.00046060965,0.000032352167,0.0003952073,0.00003583837,0.00004496606,0.00019998118],"genre_scores_gemma":[0.99238586,0.005599568,0.000024688967,0.00015175887,0.00004039404,0.00004724596,0.000059961323,0.000018199795,0.0016723047],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99914485,0.000030146206,0.00017351781,0.00031432332,0.00012215212,0.00021501722],"domain_scores_gemma":[0.9993271,0.000017665123,0.000030525513,0.00012270773,0.00002833805,0.00047366208],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000080379774,0.00013817978,0.000186615,0.000060010647,0.00007504054,0.000025152012,0.00002272121,0.000063142696,0.000031344058],"category_scores_gemma":[0.000013839647,0.00010461079,0.00002343655,0.000110362686,0.000044908174,0.00009509,0.000036332007,0.00008355056,0.0000017210806],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034833422,0.0003360559,0.88785064,0.0020876995,0.000019703122,0.0005640739,0.002355782,0.000046692167,0.07886423,0.00002584246,0.00052267534,0.02384324],"study_design_scores_gemma":[0.0077883205,0.00026995683,0.9599478,0.00041788648,0.00028688196,0.00001357965,0.00043930628,0.008466303,0.020474073,0.00061772973,0.00092710357,0.00035103902],"about_ca_topic_score_codex":0.00039528133,"about_ca_topic_score_gemma":0.00008415836,"teacher_disagreement_score":0.07209716,"about_ca_system_score_codex":0.000013976849,"about_ca_system_score_gemma":0.00013430994,"threshold_uncertainty_score":0.4265904},"labels":[],"label_agreement":null},{"id":"W4380359128","doi":"10.1038/s41419-023-05847-4","title":"Targeting transglutaminase 2 mediated exostosin glycosyltransferase 1 signaling in liver cancer stem cells with acyclic retinoid","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Blood properties and coagulation","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"RIKEN; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Tokyo Biochemical Research Foundation; Japan Agency for Medical Research and Development","keywords":"Carcinogenesis; Cancer research; Cancer stem cell; Synthetic lethality; Cancer cell; Biology; Intracellular; Cell biology; Chemistry; Biochemistry; Stem cell; Molecular biology; Cancer; Gene","score_opus":0.01867685852371057,"score_gpt":0.22281240444640443,"score_spread":0.20413554592269387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380359128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99327224,0.0054707504,0.00007994161,0.000404734,0.000043392945,0.00046777178,0.000049978986,0.000098063436,0.00011313704],"genre_scores_gemma":[0.9973451,0.0014355081,0.000039976887,0.0004508566,0.00007349214,0.00006762557,0.00009583706,0.00003340013,0.00045822057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887794,0.000050348903,0.0002118361,0.0003279461,0.00020637964,0.0003255649],"domain_scores_gemma":[0.9992028,0.000051187384,0.000031137606,0.00013350294,0.000040627154,0.00054073596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119895536,0.00017749637,0.00021857378,0.00011543023,0.00008797235,0.00002452783,0.00004203133,0.00005989783,0.00010926935],"category_scores_gemma":[0.000010376491,0.00013610175,0.00004500873,0.00030426384,0.000045656667,0.0000837092,0.00001148084,0.00013859378,0.000022029744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011181291,0.00083246577,0.2828954,0.00400433,0.0000923378,0.004715848,0.004633671,0.0047505605,0.6618878,0.00002973409,0.00091652974,0.024060022],"study_design_scores_gemma":[0.037136607,0.001981881,0.31754193,0.0039338623,0.0029542313,0.000026849244,0.0049601616,0.21409024,0.40970936,0.00013281147,0.004714185,0.00281787],"about_ca_topic_score_codex":0.00025080077,"about_ca_topic_score_gemma":0.000023466579,"teacher_disagreement_score":0.25217846,"about_ca_system_score_codex":0.000026778316,"about_ca_system_score_gemma":0.00015234723,"threshold_uncertainty_score":0.5550068},"labels":[],"label_agreement":null},{"id":"W4383067588","doi":"10.1038/s41419-023-05923-9","title":"E3 ligase HECTD3 promotes RNA virus replication and virus-induced inflammation via K33-linked polyubiquitination of PKR","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Second Military Medical University; Chinese Academy of Medical Sciences; Government of Jiangsu Province; Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; Directorate for Biological Sciences; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Protein kinase R; Viral replication; Biology; Ubiquitin ligase; Virus; Ubiquitin; Virology; RNA silencing; Cell biology; RNA; RNA virus; Kinase; Protein kinase A; RNA interference; Mitogen-activated protein kinase kinase; Genetics; Gene","score_opus":0.017416138552853105,"score_gpt":0.2576466037983409,"score_spread":0.24023046524548783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383067588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970227,0.0016462153,0.00007852573,0.00032384784,0.0001067907,0.00032922765,0.000045783057,0.000094204406,0.0003527237],"genre_scores_gemma":[0.997959,0.0003459396,0.000010927934,0.00008999899,0.000025308591,0.000037170223,0.00031057416,0.000013361103,0.0012077268],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908257,0.0001399362,0.00026482707,0.0002845119,0.00003604,0.0001921176],"domain_scores_gemma":[0.99933356,0.0001050821,0.00013199176,0.00028512639,0.00007804874,0.0000661748],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021473951,0.00013673514,0.00015892576,0.00017155244,0.00014749476,0.00002055538,0.00006991543,0.00011705907,0.00006189259],"category_scores_gemma":[0.00032647097,0.00012666937,0.000047168553,0.0001244361,0.00007823157,0.00012890517,0.000063943626,0.00009303359,0.000106844906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076459046,0.000068253474,0.00048144878,0.00009665581,0.000019389889,0.000004119465,0.00034975001,4.1306123e-7,0.97973925,0.00027829775,0.0002615267,0.01793631],"study_design_scores_gemma":[0.0008627272,0.00019729916,0.05357169,0.000038154754,0.000053371194,0.0000050411927,0.00006627884,0.0001773244,0.94323945,0.00052555196,0.0011307779,0.00013233414],"about_ca_topic_score_codex":0.00008429312,"about_ca_topic_score_gemma":0.0000046182236,"teacher_disagreement_score":0.053090245,"about_ca_system_score_codex":0.000015055516,"about_ca_system_score_gemma":0.00006754634,"threshold_uncertainty_score":0.5165427},"labels":[],"label_agreement":null},{"id":"W4383483549","doi":"10.1038/s41419-023-05921-x","title":"Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; U.S. Department of Health and Human Services; Breast Cancer Society of Canada; National Institutes of Health; University of Calgary","keywords":"SUMO protein; HDAC1; Cell biology; Biology; Histone deacetylase; Wnt signaling pathway; Epithelial–mesenchymal transition; Acetylation; Epigenetics; Cancer research; Histone; Ubiquitin; Metastasis; Signal transduction; Cancer; Genetics","score_opus":0.007779964390031594,"score_gpt":0.21715842475782696,"score_spread":0.20937846036779537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383483549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99751544,0.00078615855,0.000028507764,0.00029299682,0.000033990204,0.00024057702,0.000042879416,0.000038268226,0.001021153],"genre_scores_gemma":[0.9970423,0.00023171128,0.00007456907,0.00048777362,0.00003589806,0.000024708293,0.000301234,0.00002233951,0.001779452],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991307,0.00004807813,0.00011824486,0.0003558673,0.00007770377,0.00026938974],"domain_scores_gemma":[0.999287,0.00001252071,0.00003322657,0.00019297983,0.00003731905,0.00043691637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010118498,0.00015448667,0.00012621534,0.00008076894,0.00006014758,0.000047177036,0.00008245111,0.000080595164,0.000012335751],"category_scores_gemma":[0.000093962095,0.00013533271,0.000022095131,0.00019917019,0.000027554495,0.000007600055,0.00013941663,0.00006499635,0.000015868543],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030779892,0.00044407335,0.25691983,0.00044907242,0.00011086274,0.00074196747,0.0009923931,0.00012365433,0.71874017,0.00029199998,0.0060041393,0.01210388],"study_design_scores_gemma":[0.004113291,0.00095110113,0.7693954,0.00023545508,0.000086901164,0.000010173505,0.00015948011,0.0008136706,0.21644445,0.0013207828,0.0054946775,0.0009745903],"about_ca_topic_score_codex":0.000025142532,"about_ca_topic_score_gemma":0.000034656143,"teacher_disagreement_score":0.5124756,"about_ca_system_score_codex":0.000009181079,"about_ca_system_score_gemma":0.0000836658,"threshold_uncertainty_score":0.55187076},"labels":[],"label_agreement":null},{"id":"W4384202159","doi":"10.1038/s41419-023-05936-4","title":"A Dhdds K42E knock-in RP59 mouse model shows inner retina pathology and defective synaptic transmission","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"National Center for Advancing Translational Sciences; Natural Sciences and Engineering Research Council of Canada; Narodowe Centrum Nauki; Ögonfonden; National Eye Institute; University of Guelph; University at Buffalo; Knights Templar Eye Foundation; U.S. Department of Veterans Affairs; U.S. Department of Health and Human Services; National Institutes of Health; Government of Canada","keywords":"Outer nuclear layer; Retinal degeneration; Retina; Retinitis pigmentosa; Biology; Retinal; Electroretinography; Inner nuclear layer; Outer plexiform layer; Photoreceptor cell; Cell biology; Molecular biology; Neuroscience; Biochemistry","score_opus":0.008374012081549911,"score_gpt":0.22405356123003803,"score_spread":0.2156795491484881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384202159","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99529636,0.0019727326,0.00074807595,0.00014580923,0.000020078318,0.00019299184,0.000021042782,0.000022761003,0.0015801608],"genre_scores_gemma":[0.9953662,0.0019350011,0.000224594,0.00024744088,0.000015913842,0.000042297946,0.00014782288,0.000018212073,0.0020025074],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990844,0.000047803842,0.00013139681,0.00040389146,0.00006928958,0.00026321426],"domain_scores_gemma":[0.99948776,0.000013277094,0.000024985186,0.00013707494,0.00002168938,0.00031523773],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105723804,0.00015881739,0.00012547556,0.00007784094,0.00007367013,0.000018509736,0.000060628805,0.000109469554,0.000008804243],"category_scores_gemma":[0.0000587219,0.00014212614,0.000047095236,0.000082862425,0.00006402694,0.000005557353,0.000074446194,0.00006658278,0.0000070309643],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033946997,0.00053463137,0.25943917,0.00075562776,0.00006776767,0.00065930956,0.0012762811,0.0015305866,0.71052104,0.000696359,0.0058808317,0.015243673],"study_design_scores_gemma":[0.027198054,0.0029454615,0.52529234,0.0004150009,0.0007980772,0.00010845172,0.0026658492,0.22412573,0.13676232,0.049018648,0.024083901,0.0065861503],"about_ca_topic_score_codex":0.000005372305,"about_ca_topic_score_gemma":0.000005320994,"teacher_disagreement_score":0.5737587,"about_ca_system_score_codex":0.0000060539655,"about_ca_system_score_gemma":0.000096173535,"threshold_uncertainty_score":0.5795736},"labels":[],"label_agreement":null},{"id":"W4384922276","doi":"10.1038/s41419-023-05991-x","title":"Apoptotic exosome-like vesicles transfer specific and functional mRNAs to endothelial cells by phosphatidylserine-dependent macropinocytosis","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; Centre Hospitalier de l’Université de Montréal; Héma-Québec; Centre hospitalier universitaire de Québec; Université de Montréal; Translational Research in Oncology","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Montréal; Fondation Jean-Louis Lévesque; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Cell biology; Pinocytosis; Endocytosis; Internalization; Biology; Microvesicles; Exosome; Phosphatidylserine; Apoptosis; Flow cytometry; Molecular biology; Cell; microRNA; Biochemistry; Phospholipid","score_opus":0.010547703110444812,"score_gpt":0.21119907618787184,"score_spread":0.20065137307742703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384922276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908936,0.006031671,0.0012975263,0.00016810988,0.0002647195,0.0003527846,0.00066425686,0.00005266119,0.00027469295],"genre_scores_gemma":[0.99267167,0.0024025298,0.00012535829,0.00061882014,0.0002255473,0.00006359428,0.00036448904,0.000050068513,0.0034779077],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99849933,0.000045674522,0.00020569783,0.000649192,0.00021565975,0.0003844539],"domain_scores_gemma":[0.99852765,0.000019418238,0.000022926492,0.00033822705,0.000033970708,0.0010578028],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008183552,0.00025951752,0.0001521101,0.00006333497,0.00015065295,0.000081800295,0.00012591679,0.000080543505,0.000092379785],"category_scores_gemma":[0.000018318096,0.00026478036,0.00009050625,0.000105878324,0.00008476287,0.000010412588,0.00013437886,0.0000690041,0.00011766196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006173493,0.00015014535,0.0041707237,0.00011141221,0.000025884925,0.000060777533,0.000034447978,0.00005986304,0.97826356,0.000108425134,0.014815189,0.0015822371],"study_design_scores_gemma":[0.002233492,0.00020571846,0.01768176,0.000021576378,0.00010476563,0.0000057485577,0.000114353556,0.00011206118,0.9034469,0.00032208656,0.0751256,0.00062590453],"about_ca_topic_score_codex":0.0000068003037,"about_ca_topic_score_gemma":0.0000016203084,"teacher_disagreement_score":0.07481661,"about_ca_system_score_codex":0.000013182813,"about_ca_system_score_gemma":0.00006613193,"threshold_uncertainty_score":0.99998045},"labels":[],"label_agreement":null},{"id":"W4385597019","doi":"10.1038/s41419-023-06015-4","title":"Heterogeneity in leukemia cells that escape drug-induced senescence-like state","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vector Institute; Ontario Institute for Cancer Research; Université de Montréal; Hôpital Maisonneuve-Rosemont; Princess Margaret Cancer Centre; University Health Network; University of Toronto; Public Health Ontario; York University","funders":"Canadian Institutes of Health Research; York University; Genome Canada","keywords":"Senescence; Biology; Leukemia; Cancer cell; Cancer research; Phenotype; Lysosome; Cell growth; Cell biology; Apoptosis; Cancer; Gene; Immunology; Genetics; Biochemistry; Enzyme","score_opus":0.028107567831384375,"score_gpt":0.26149120233261675,"score_spread":0.23338363450123237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385597019","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99751776,0.00074521685,0.000010027541,0.00019838722,0.00031341708,0.0004154696,0.00004769256,0.00018870109,0.00056330825],"genre_scores_gemma":[0.995209,0.0012846728,0.00004604504,0.0009262049,0.000078002144,0.00002809848,0.00008026211,0.000035336925,0.0023123727],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981769,0.00007011419,0.00025809743,0.00057412416,0.0003257846,0.0005949776],"domain_scores_gemma":[0.9981133,0.00006539862,0.0000598965,0.00044753915,0.000040351588,0.0012735218],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017806236,0.00027759906,0.00034192478,0.00023444572,0.00010777916,0.000046227717,0.000116766845,0.0000680738,0.000044208806],"category_scores_gemma":[0.00003910491,0.00024870428,0.00011192772,0.0004009239,0.000064316344,0.00011928885,0.0000903525,0.00019273358,0.00022261488],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007597713,0.00027788544,0.90178734,0.000830276,0.00002131693,0.0030270114,0.00075712544,0.00004394855,0.07941063,0.000013435327,0.0045089507,0.008562303],"study_design_scores_gemma":[0.0031280096,0.00007341565,0.92709506,0.0001696957,0.0000939218,0.000009446777,0.0002988095,0.0021872884,0.06418539,0.00018955968,0.0020998297,0.00046960768],"about_ca_topic_score_codex":0.00021348179,"about_ca_topic_score_gemma":0.00005007476,"teacher_disagreement_score":0.025307681,"about_ca_system_score_codex":0.00009323001,"about_ca_system_score_gemma":0.00041231766,"threshold_uncertainty_score":0.99999654},"labels":[],"label_agreement":null},{"id":"W4386094257","doi":"10.1038/s41419-023-06080-9","title":"Dysfunctional endocannabinoid CB1 receptor expression and signaling contribute to skeletal muscle cell toxicity induced by simvastatin","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Endocannabinoid system; Simvastatin; Cannabinoid receptor; Rimonabant; C2C12; Pharmacology; Cannabinoid; Myopathy; Cannabinoid receptor type 2; Biology; Myocyte; Receptor; Chemistry; Cell biology; Internal medicine; Myogenesis; Antagonist; Medicine; Biochemistry","score_opus":0.01426425830365522,"score_gpt":0.2652371669880189,"score_spread":0.25097290868436367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386094257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936106,0.0009303776,0.00012436323,0.003620804,0.0001182051,0.0006288306,0.00043987943,0.00009530731,0.0004315951],"genre_scores_gemma":[0.9865801,0.00009316798,0.000067488625,0.0009901967,0.0001952179,0.00013412329,0.00038488526,0.000032075626,0.011522774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99818754,0.00006776179,0.00023097289,0.00052503054,0.00046232497,0.0005263886],"domain_scores_gemma":[0.99747664,0.00003823391,0.000046684414,0.00021175925,0.00013716327,0.0020895288],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023708623,0.00021717892,0.00025393753,0.00015410646,0.00025199028,0.00007961605,0.00006671952,0.000078273195,0.00034450748],"category_scores_gemma":[0.00026036776,0.00018799085,0.00008452255,0.00027587372,0.000055584693,0.000089319976,0.00014302101,0.00021217325,0.00007350437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004259775,0.00020036713,0.00231092,0.00028408127,0.0000072311755,0.00006814734,0.00011731199,0.000011220729,0.76922643,0.00001484244,0.22468142,0.0026520193],"study_design_scores_gemma":[0.014052216,0.00216877,0.15288442,0.00034154623,0.00025923422,0.000011025108,0.0014862358,0.0020608192,0.48064926,0.00044029017,0.34430784,0.0013383292],"about_ca_topic_score_codex":0.000042730117,"about_ca_topic_score_gemma":0.0000011764689,"teacher_disagreement_score":0.2885772,"about_ca_system_score_codex":0.000053643107,"about_ca_system_score_gemma":0.0002680664,"threshold_uncertainty_score":0.7666044},"labels":[],"label_agreement":null},{"id":"W4386373681","doi":"10.1038/s41419-023-06106-2","title":"Three-dimensional growth sensitizes breast cancer cells to treatment with ferroptosis-promoting drugs","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; CIHR Skin Research Training Centre; IWK Health Centre; Government of Canada; Dalhousie Medical Research Foundation; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Autophagy; Gene knockdown; Programmed cell death; Downregulation and upregulation; Cancer research; Cancer cell; Cell growth; Cell culture; Cell biology; Small interfering RNA; RNA interference; Apoptosis; Biology; Cell; Chemistry; Transfection; Cancer; RNA; Biochemistry","score_opus":0.013959209943846466,"score_gpt":0.24706174439843603,"score_spread":0.23310253445458956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386373681","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99243134,0.000685607,0.000013228951,0.005560012,0.00008793711,0.0005408163,0.00021530715,0.00015087724,0.00031489288],"genre_scores_gemma":[0.997072,0.00028763278,0.00019240651,0.0014364722,0.00019343855,0.0001970584,0.00005775981,0.000043399155,0.0005198459],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998622,0.000016945889,0.00015534787,0.0004971606,0.00029563167,0.00041292343],"domain_scores_gemma":[0.99829453,0.0000325196,0.00004005902,0.00021853177,0.000114014525,0.0013003481],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005729616,0.00025988143,0.00029107896,0.00011127228,0.00016964905,0.00004112211,0.000040595154,0.00004070104,0.000139034],"category_scores_gemma":[0.000005442931,0.0001779979,0.00009344534,0.00029447972,0.000043954537,0.000052219846,0.00005185355,0.00006366565,0.00007282737],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007821904,0.001963942,0.8618262,0.0016116941,0.0005009581,0.001515778,0.002011502,0.00024269475,0.041958574,0.00020215489,0.01857637,0.061768267],"study_design_scores_gemma":[0.010985015,0.0023975691,0.9004076,0.0011560923,0.0023625917,0.00005904993,0.0005775335,0.009382286,0.06838139,0.00022078445,0.0026911576,0.0013788884],"about_ca_topic_score_codex":0.0004563085,"about_ca_topic_score_gemma":0.00003352427,"teacher_disagreement_score":0.060389377,"about_ca_system_score_codex":0.00009672023,"about_ca_system_score_gemma":0.00027835075,"threshold_uncertainty_score":0.7258544},"labels":[],"label_agreement":null},{"id":"W4386470839","doi":"10.1038/s41419-023-06116-0","title":"A small molecule 20C from Gastrodia elata inhibits α-synuclein aggregation and prevents progression of Parkinson’s disease","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Microscale thermophoresis; Cell biology; Transcriptome; Biophysics; Biochemistry; Biology","score_opus":0.02012944251850282,"score_gpt":0.2524386482343413,"score_spread":0.2323092057158385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386470839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99321306,0.005040951,0.000054575314,0.00013942305,0.000052333984,0.0006777369,0.0005824471,0.000086110456,0.00015337979],"genre_scores_gemma":[0.9972517,0.0007830348,0.00043879365,0.000121035184,0.00005426748,0.00009693669,0.0008764965,0.000032401214,0.00034533974],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986542,0.000053773212,0.00022367462,0.0005144055,0.00026676868,0.0002872154],"domain_scores_gemma":[0.99786925,0.000030969288,0.00011228389,0.00032052124,0.0000419431,0.0016250501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000069570066,0.00023008778,0.00025599805,0.00012555547,0.000099665696,0.000030275376,0.000053524178,0.000053892,0.000050036408],"category_scores_gemma":[0.000095730764,0.00019628262,0.000094341085,0.00015090166,0.000051437215,0.000089830435,0.00011268343,0.00006718525,0.000028036782],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040847184,0.001471763,0.9594055,0.0008104261,0.00012109912,0.001355083,0.00017281235,0.0000047755216,0.005249361,0.00009695324,0.0006946008,0.02653292],"study_design_scores_gemma":[0.0050046006,0.0002884449,0.9800741,0.0006992394,0.0009559652,0.0000019644904,0.000044284367,0.002822797,0.0067060674,0.001998085,0.0011659547,0.00023846175],"about_ca_topic_score_codex":0.00003072456,"about_ca_topic_score_gemma":0.0000018537163,"teacher_disagreement_score":0.026294459,"about_ca_system_score_codex":0.000024155044,"about_ca_system_score_gemma":0.00016103209,"threshold_uncertainty_score":0.8004173},"labels":[],"label_agreement":null},{"id":"W4386955537","doi":"10.1038/s41419-023-06134-y","title":"Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health","funders":"National Natural Science Foundation of China","keywords":"Psoriasis; Keratinocyte; Imiquimod; Cancer research; Apoptosis; Downregulation and upregulation; Immunology; Medicine; Biology; Cell culture; Biochemistry; Genetics","score_opus":0.016665718748192615,"score_gpt":0.22912000295041346,"score_spread":0.21245428420222084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386955537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99478024,0.0042704926,0.000085829764,0.00008947351,0.0002783267,0.00022217662,0.000057669426,0.0000681455,0.00014765875],"genre_scores_gemma":[0.99872804,0.00030132054,0.00011801819,0.000082867904,0.00003968687,0.00004748789,0.00051406387,0.000016121683,0.00015241261],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989149,0.00016582065,0.0003043983,0.0002660869,0.000039442795,0.00030935358],"domain_scores_gemma":[0.9994746,0.00015517745,0.00010569515,0.00014326922,0.00003543217,0.00008582957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016615923,0.00017520279,0.00025121224,0.0001595472,0.00014138904,0.000014365212,0.00007689938,0.00011048937,0.00009804791],"category_scores_gemma":[0.000095499665,0.00016211224,0.000081613514,0.00019332903,0.000031327818,0.00008400716,0.000045928915,0.00007773994,0.00014040274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027969386,0.00021367252,0.2345354,0.00029704583,0.00009967101,0.00010498,0.00080794253,0.00008654555,0.74215245,0.000067251734,0.0006879639,0.020667369],"study_design_scores_gemma":[0.006712015,0.00022980335,0.3598985,0.00023182404,0.00049582263,0.000008836942,0.00062830263,0.0016171897,0.6272118,0.0018552315,0.00040086743,0.0007097756],"about_ca_topic_score_codex":0.000101924445,"about_ca_topic_score_gemma":0.00001027988,"teacher_disagreement_score":0.12536311,"about_ca_system_score_codex":0.000020141724,"about_ca_system_score_gemma":0.0000627984,"threshold_uncertainty_score":0.6610745},"labels":[],"label_agreement":null},{"id":"W4387569890","doi":"10.1038/s41419-023-06213-0","title":"DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universität Zürich; Ontario Genomics Institute; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Genomics; Genome Canada; McGill University; Bayer; Genentech; Deutsche Krebshilfe; Pfizer; Deutsche Forschungsgemeinschaft; Bristol-Myers Squibb","keywords":"Tetramer; Dimer; Ankyrin repeat; Biology; Biophysics; Cell biology; Chemistry; Biochemistry; Gene; Enzyme","score_opus":0.01173400530123071,"score_gpt":0.23439474318597436,"score_spread":0.22266073788474366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387569890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939734,0.005228141,0.00002079835,0.00006765225,0.000026367985,0.00032272245,0.0000502631,0.000009000013,0.0003016816],"genre_scores_gemma":[0.9993462,0.0005085822,0.00001872517,0.0000453479,0.000011193817,0.000010624088,0.000021167607,0.000009349115,0.000028816006],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9994255,0.000033903187,0.00017712616,0.00013283393,0.000100645084,0.00013000274],"domain_scores_gemma":[0.99960476,0.000047332505,0.000049165366,0.00013036061,0.000015838763,0.0001525289],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009097127,0.00008322022,0.00015471554,0.00014031876,0.000019419685,0.0000060100097,0.000026924874,0.00004015501,0.0000039715082],"category_scores_gemma":[0.000058433317,0.000065550405,0.000026410698,0.00014925493,0.00007248152,0.000040393854,0.000032915716,0.0000799665,0.0000010665409],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045676935,0.00056566874,0.5075705,0.0076686745,0.000018747387,0.0008012686,0.011292162,0.00041100613,0.44281238,0.000057501537,0.0004085876,0.023825785],"study_design_scores_gemma":[0.009043952,0.00078469486,0.72646904,0.00023056947,0.00022076836,0.000015619087,0.0011272638,0.010096444,0.25108603,0.00042994978,0.00025845767,0.00023717782],"about_ca_topic_score_codex":0.00018277849,"about_ca_topic_score_gemma":0.00005647828,"teacher_disagreement_score":0.21889853,"about_ca_system_score_codex":0.000016021082,"about_ca_system_score_gemma":0.000054871973,"threshold_uncertainty_score":0.2673068},"labels":[],"label_agreement":null},{"id":"W4387806378","doi":"10.1038/s41419-023-06215-y","title":"Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Qatar National Research Fund; Khalifa University of Science, Technology and Research; Fonds National de la Recherche Luxembourg; Weill Cornell Medical College; York University; Hamad Bin Khalifa University","keywords":"Ubiquitin ligase; Biology; Cell biology; Ubiquitin; Hedgehog signaling pathway; Genetic screen; Signal transduction; Genetics; Mutant; Gene","score_opus":0.00765968370246805,"score_gpt":0.22239311964220493,"score_spread":0.21473343593973687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387806378","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99228615,0.003178671,0.003833861,0.00002731327,0.000053898573,0.00019676746,0.00023271149,0.000022671798,0.00016796011],"genre_scores_gemma":[0.9987936,0.000096951015,0.00001913109,0.00011482392,0.000079064324,0.000027981456,0.00056117825,0.000017215303,0.00029002473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990822,0.00005463485,0.00025450694,0.00025954048,0.00017718879,0.00017189333],"domain_scores_gemma":[0.99927574,0.00003401948,0.0001425508,0.00016814258,0.000105259925,0.0002742944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016262561,0.00012380673,0.00014180683,0.00006797154,0.00005182382,0.000012249796,0.00008510886,0.000076384305,0.00002843221],"category_scores_gemma":[0.00016002284,0.00012605541,0.00008904005,0.00008427578,0.000049451897,0.0000059046456,0.000044266955,0.000039675037,0.000004928273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008602538,0.0002124398,0.008189034,0.00027931613,0.000035613826,0.0000061378514,0.000022624692,0.00043607282,0.9867993,0.00007407903,0.001548345,0.0015368073],"study_design_scores_gemma":[0.002440174,0.00032773553,0.017614052,0.00005276984,0.00020745798,4.2549578e-7,0.00009132533,0.0010880897,0.97604364,0.0003672038,0.0015451516,0.00022196154],"about_ca_topic_score_codex":0.000006941483,"about_ca_topic_score_gemma":7.097813e-7,"teacher_disagreement_score":0.010755623,"about_ca_system_score_codex":0.0000059284084,"about_ca_system_score_gemma":0.00012269395,"threshold_uncertainty_score":0.51403904},"labels":[],"label_agreement":null},{"id":"W4387949266","doi":"10.1038/s41419-023-06224-x","title":"Lamin A upregulation reorganizes the genome during rod photoreceptor degeneration","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Government of Canada; Ottawa Hospital Research Institute; CIHR Skin Research Training Centre; Canadian Institutes of Health Research; University of Ottawa","keywords":"Lamin; Heterochromatin; Nuclear lamina; Downregulation and upregulation; Biology; Cell biology; Retinitis pigmentosa; Intermediate filament; Chromatin; Genetics; Gene; Nucleus; Nuclear protein; Cytoskeleton; Transcription factor; Cell","score_opus":0.004743755901978475,"score_gpt":0.18643669640176969,"score_spread":0.1816929404997912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387949266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99885756,0.00045023285,0.0000748879,0.00010182489,0.00010635286,0.00010444813,0.000012789594,0.000022667802,0.0002692389],"genre_scores_gemma":[0.9971361,0.00014948056,0.0000354274,0.00011450569,0.00034557926,0.000009810139,0.000303853,0.000012048595,0.001893188],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9996089,0.000019472505,0.000059142993,0.00016338944,0.000052408326,0.00009671347],"domain_scores_gemma":[0.99971974,0.0000027225665,0.000020706837,0.00014288149,0.000019144081,0.00009481996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000036093916,0.000066110384,0.000035127112,0.000017706536,0.00015526231,0.000029468107,0.00003790438,0.000037214082,0.000031569285],"category_scores_gemma":[0.000024027857,0.000049600705,0.00002637207,0.00005807443,0.000017325205,0.0000036496947,0.000035963087,0.000023359566,0.000021157653],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097445656,0.000007174806,0.0044637867,0.000018687704,0.0000054260563,0.000001758818,0.000043795615,0.000074302865,0.9940477,0.000051716634,0.0008688215,0.00031940045],"study_design_scores_gemma":[0.0007513864,0.00008067637,0.6976203,0.0000046756413,0.00006231278,0.000003673905,0.00010227383,0.00065171847,0.27946016,0.00043410505,0.020594118,0.0002346284],"about_ca_topic_score_codex":0.0000025315587,"about_ca_topic_score_gemma":0.0000020528173,"teacher_disagreement_score":0.7145875,"about_ca_system_score_codex":0.0000045864285,"about_ca_system_score_gemma":0.000020273763,"threshold_uncertainty_score":0.2022658},"labels":[],"label_agreement":null},{"id":"W4388573959","doi":"10.1038/s41419-023-06251-8","title":"Aggregation of alpha-synuclein disrupts mitochondrial metabolism and induce mitophagy via cardiolipin externalization","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec; Université de Moncton","funders":"","keywords":"Mitophagy; Parkin; Mitochondrion; Cell biology; Substantia nigra; Biology; Alpha-synuclein; Pars compacta; Dopaminergic; Cardiolipin; Autophagy; Parkinson's disease; Chemistry; Neuroscience; Biochemistry; Dopamine; Internal medicine; Medicine; Phospholipid","score_opus":0.014928260263553109,"score_gpt":0.2553115199911103,"score_spread":0.2403832597275572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388573959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931906,0.005229736,0.0005150202,0.00006063946,0.00025402344,0.00037853612,0.00009624472,0.00005488141,0.00022032164],"genre_scores_gemma":[0.9979648,0.00085406937,0.00021769482,0.000097530494,0.0002129505,0.000041778283,0.0001929431,0.000022039167,0.00039620703],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99905854,0.000042798805,0.00017980367,0.00031202007,0.00022133131,0.00018547446],"domain_scores_gemma":[0.999003,0.000022636572,0.00007654741,0.00019825908,0.000052358995,0.0006471802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004506342,0.00015913417,0.00025911344,0.00013484227,0.00007514647,0.000021841537,0.000033248136,0.000056580095,0.00003227553],"category_scores_gemma":[0.00006152347,0.00013824872,0.00008826676,0.00016215333,0.000035874247,0.00010084545,0.000042285144,0.000041915748,0.00001673929],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007884143,0.0026552705,0.53514177,0.003446245,0.0011021211,0.0033660973,0.0017488038,0.00007303544,0.2538686,0.004812502,0.0037311688,0.18217026],"study_design_scores_gemma":[0.007209775,0.00014866734,0.9557742,0.00015829796,0.0013020642,0.000014971186,0.000057686673,0.003370555,0.02267638,0.004708282,0.004296942,0.00028218632],"about_ca_topic_score_codex":0.000045066103,"about_ca_topic_score_gemma":9.589855e-7,"teacher_disagreement_score":0.42063242,"about_ca_system_score_codex":0.000014634901,"about_ca_system_score_gemma":0.00007025899,"threshold_uncertainty_score":0.56376195},"labels":[],"label_agreement":null},{"id":"W4388631070","doi":"10.1038/s41419-023-06263-4","title":"Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"China Postdoctoral Science Foundation; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Bone resorption; Osteoclast; Methylation; DNA methylation; Cancer research; Osteoporosis; Cell biology; Chemistry; Epigenetics; Biology; Endocrinology; Biochemistry; Gene expression; Gene","score_opus":0.02399932686936706,"score_gpt":0.2590252885485896,"score_spread":0.23502596167922252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388631070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99738985,0.0012840361,0.00052909314,0.00013504061,0.00010221498,0.0002145953,0.00008946406,0.000022084556,0.0002336259],"genre_scores_gemma":[0.9975537,0.00023796105,0.0001774255,0.000112795045,0.00008001292,0.000043703938,0.000340667,0.000015905935,0.0014378433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992086,0.000049326976,0.00017278087,0.00029799063,0.00010851565,0.00016276161],"domain_scores_gemma":[0.9992771,0.000014915852,0.00006552274,0.00027975586,0.00009944492,0.00026324333],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012147471,0.000112334084,0.00011563048,0.00010020605,0.000069774826,0.00001695556,0.000065934975,0.00006988278,0.000021091246],"category_scores_gemma":[0.000084672574,0.000109110966,0.00006466471,0.00020309883,0.000023831852,0.0000070268065,0.00005378696,0.0000321123,0.000017426215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001928802,0.000034281853,0.0022252956,0.00003547209,0.00001243068,0.000001965104,0.00003636962,0.00014295745,0.988902,0.00002975871,0.0014558085,0.0069308206],"study_design_scores_gemma":[0.00052210083,0.0001685461,0.14767127,0.000018213568,0.00006215991,6.701745e-7,0.00008445836,0.00044209362,0.8481229,0.00027307874,0.0024362355,0.0001982613],"about_ca_topic_score_codex":0.000026801385,"about_ca_topic_score_gemma":0.0000068582194,"teacher_disagreement_score":0.14544597,"about_ca_system_score_codex":0.000010491543,"about_ca_system_score_gemma":0.000090236914,"threshold_uncertainty_score":0.4449416},"labels":[],"label_agreement":null},{"id":"W4388937305","doi":"10.1038/s41419-023-06283-0","title":"Deciphering the interaction between Twist1 and PPARγ during adipocyte differentiation","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Science Foundation of Henan Province; Henan University; National Natural Science Foundation of China","keywords":"Adipocyte; Cellular differentiation; Cell biology; Peroxisome proliferator-activated receptor; Biology; Biochemistry; Receptor; Adipose tissue; Gene","score_opus":0.023269527910467554,"score_gpt":0.274532711029533,"score_spread":0.2512631831190655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388937305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961152,0.0026788884,0.00006348482,0.00025571487,0.00009251201,0.00016795362,0.0000061567125,0.00005308374,0.0005669959],"genre_scores_gemma":[0.9966357,0.0006119274,0.000014674688,0.00008245118,0.0002787584,0.000013636924,0.000039265287,0.000011492295,0.0023121303],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99951893,0.000016661832,0.00009473436,0.00014896806,0.00008407828,0.00013662674],"domain_scores_gemma":[0.9994748,0.000039135306,0.000028496373,0.000121719706,0.0000138703135,0.00032197963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045142617,0.00008121738,0.00010588438,0.00004436113,0.00012338343,0.000028059862,0.000022048922,0.000023736295,0.000034675577],"category_scores_gemma":[0.000047996105,0.000056980065,0.000030240299,0.00007049414,0.000020462316,0.00007137122,0.000040579773,0.000072511095,0.000037271082],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047133098,0.00006916019,0.9440941,0.0006177293,0.00009962964,0.00014492954,0.0012243195,0.000010965059,0.014213399,0.00022067166,0.0007435262,0.038090244],"study_design_scores_gemma":[0.0007436625,0.0000151791355,0.9922202,0.00004132221,0.0003391257,0.000003670185,0.00010006882,0.00038516402,0.0016642814,0.00023154421,0.004187788,0.00006796917],"about_ca_topic_score_codex":0.000012619866,"about_ca_topic_score_gemma":8.9771635e-7,"teacher_disagreement_score":0.04812613,"about_ca_system_score_codex":0.0000087750905,"about_ca_system_score_gemma":0.000016999058,"threshold_uncertainty_score":0.23235796},"labels":[],"label_agreement":null},{"id":"W4389489603","doi":"10.1038/s41419-023-06241-w","title":"m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Zhongnan Hospital of Wuhan University; Wuhan University; Health Commission of Hubei Province","keywords":"Sting; Immunity; Cell biology; Chemistry; Cancer research; Biology; Immune system; Immunology","score_opus":0.021789507232885377,"score_gpt":0.2685664573747819,"score_spread":0.24677695014189654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389489603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99600565,0.0010703505,0.0023284047,0.000081750724,0.000017213302,0.00009791753,0.000040624353,0.000010142193,0.00034794817],"genre_scores_gemma":[0.9983916,0.0009008132,0.000081289414,0.000036215373,0.000025848176,0.000023339839,0.00020979319,0.0000058753867,0.0003251816],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995729,0.00002148886,0.00009533148,0.0001616918,0.000051493975,0.00009711418],"domain_scores_gemma":[0.9996095,0.000012810696,0.00004345967,0.00016851694,0.00005110745,0.00011462193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000077532735,0.00006308555,0.000056342527,0.00002926079,0.000080992184,0.000011976667,0.000038783943,0.000032141063,0.0000062107956],"category_scores_gemma":[0.000067806184,0.000060027163,0.000020675843,0.00006760979,0.000049872408,0.0000062883346,0.000032852327,0.000024949535,0.0000020227974],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000090256384,0.0000455505,0.029920889,0.00011434761,0.000010582736,3.37073e-7,0.00007710222,0.00013494199,0.95750785,0.00013635038,0.00022799979,0.011733767],"study_design_scores_gemma":[0.0008134861,0.00010110536,0.78239185,0.000029290364,0.00005717827,5.612208e-7,0.00045630347,0.007197484,0.2040854,0.001784728,0.0028208373,0.00026177036],"about_ca_topic_score_codex":0.000042151412,"about_ca_topic_score_gemma":0.000001012227,"teacher_disagreement_score":0.7534225,"about_ca_system_score_codex":0.0000043739883,"about_ca_system_score_gemma":0.000043535685,"threshold_uncertainty_score":0.24478367},"labels":[],"label_agreement":null},{"id":"W4391722169","doi":"10.1038/s41419-024-06523-x","title":"CHCHD2 up-regulation in Huntington disease mediates a compensatory protective response against oxidative stress","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"Oxidative stress; Biology; Gene knockdown; Huntington's disease; Cell biology; Oxidative phosphorylation; Phenotype; Mitochondrion; Induced pluripotent stem cell; Apoptosis; Cell; Gene; Disease; Genetics; Endocrinology; Internal medicine; Medicine; Biochemistry","score_opus":0.01921659144924337,"score_gpt":0.25641128910821687,"score_spread":0.2371946976589735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391722169","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964264,0.001082502,0.00011314654,0.00027733165,0.0002547528,0.0009774093,0.00048579686,0.0001435217,0.00023915482],"genre_scores_gemma":[0.9985734,0.00006207781,0.000018190796,0.0006239957,0.000078199424,0.0002464371,0.000039387607,0.00004074659,0.0003175708],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974321,0.0006725647,0.00025118905,0.0009247513,0.0003530877,0.00036628946],"domain_scores_gemma":[0.9981732,0.00053595204,0.00006294022,0.00031065004,0.000048745795,0.0008685463],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016724116,0.0002931746,0.0001812973,0.00027770875,0.00017248058,0.0001996038,0.00016178291,0.000038503353,0.000045881527],"category_scores_gemma":[0.0017221051,0.00027401137,0.00008829013,0.0003587267,0.00019382962,0.00027260726,0.00012197731,0.00016779885,0.00005531125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0053301994,0.00066845847,0.040632892,0.00072071026,0.000009372206,0.00044520592,0.0014333708,0.0013284207,0.9458856,0.0013306285,0.0002867743,0.0019283494],"study_design_scores_gemma":[0.0008187732,0.00007073989,0.3689066,0.00020099443,0.000057558067,2.8312448e-7,0.00013513911,0.009833639,0.61679727,0.0025339413,0.00024370443,0.00040140885],"about_ca_topic_score_codex":0.000008038627,"about_ca_topic_score_gemma":0.000004194683,"teacher_disagreement_score":0.3290884,"about_ca_system_score_codex":0.00006647831,"about_ca_system_score_gemma":0.00047316708,"threshold_uncertainty_score":0.9999712},"labels":[],"label_agreement":null},{"id":"W4392878999","doi":"10.1038/s41419-024-06591-z","title":"Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Fondo Nacional de Desarrollo Científico y Tecnológico; Natural Sciences and Engineering Research Council of Canada; Comisión Nacional de Investigación Científica y Tecnológica; Dr. Rolf M. Schwiete Stiftung; Canadian Institutes of Health Research; Universidad de Concepción; Consejo Nacional de Innovación, Ciencia y Tecnología; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Biology; Kinase; Cell biology; Programmed cell death; Casein kinase 2; Phosphorylation; Protein kinase A; Biochemistry; Cancer research; Cyclin-dependent kinase 2; Apoptosis","score_opus":0.006181277190157434,"score_gpt":0.2291769863421469,"score_spread":0.22299570915198946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392878999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9252227,0.07392925,0.000003389693,0.00032695665,0.00016125121,0.0001300428,0.000053748216,0.000006596296,0.00016607474],"genre_scores_gemma":[0.99213463,0.006781173,0.0000070979095,0.00027719405,0.00009966669,0.00004075896,0.00004264464,0.000009505511,0.0006073269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994897,0.000024405685,0.000080389254,0.00022818404,0.000049314687,0.00012800303],"domain_scores_gemma":[0.99972224,0.000011696223,0.00001647294,0.00008541242,0.000010952611,0.00015323113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004489675,0.00009616876,0.000059128044,0.000021759817,0.000055356824,0.00005270281,0.000045544373,0.00004843361,0.000014961014],"category_scores_gemma":[0.0000075461016,0.00006192564,0.000026652726,0.00005302159,0.00005332538,0.0000051692778,0.000033670596,0.000072590025,0.0000020799446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029903726,0.000050582945,0.002540233,0.00025299034,0.00003079703,0.00020436705,0.00014610885,0.00013997128,0.9864229,0.00008107934,0.0037222211,0.006109687],"study_design_scores_gemma":[0.00065506325,0.000108654094,0.008628514,0.00010669086,0.00011462298,0.0000074710233,0.00017163597,0.0009908183,0.9592224,0.00027733913,0.029449532,0.00026728614],"about_ca_topic_score_codex":0.00018528708,"about_ca_topic_score_gemma":0.000035411344,"teacher_disagreement_score":0.067148075,"about_ca_system_score_codex":0.000009611785,"about_ca_system_score_gemma":0.00011018833,"threshold_uncertainty_score":0.25252542},"labels":[],"label_agreement":null},{"id":"W4392986702","doi":"10.1038/s41419-024-06603-y","title":"DMRTA2 supports glioma stem-cell mediated neovascularization in glioblastoma","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministerstwo Edukacji i Nauki; London Health Sciences Centre","keywords":"Glioma; Cancer research; Biology; Stem cell; Progenitor cell; Angiogenesis; Cancer stem cell; Neural stem cell; Stem cell marker; Neurosphere; Pericyte; Pathology; Cell biology; Medicine; Endothelial stem cell; In vitro; Adult stem cell","score_opus":0.005131092644683085,"score_gpt":0.23138745327781604,"score_spread":0.22625636063313295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392986702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9699784,0.02195979,0.005989399,0.000108564236,0.0002039205,0.00041993873,0.00006761194,0.000046577487,0.0012258281],"genre_scores_gemma":[0.99745494,0.000818776,0.000034148314,0.00014066801,0.00008948724,0.000050272884,0.00028864766,0.00004233067,0.0010807135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986706,0.0000705906,0.00018004901,0.0005316181,0.00021907789,0.00032810448],"domain_scores_gemma":[0.99912876,0.000012454613,0.000022116947,0.0003020528,0.000044334873,0.0004902957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014206892,0.00017682268,0.00011586314,0.00017999545,0.000047911846,0.00008842368,0.00010717253,0.00015266497,0.00007031931],"category_scores_gemma":[0.000033983437,0.00017774198,0.00009514958,0.00027745534,0.00003672076,0.00000842065,0.00011284361,0.00012528445,0.000042150896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040144674,0.00017888556,0.00047693413,0.0004477888,0.00003704513,0.0014224023,0.000066452085,0.00026296655,0.99130225,0.0002021159,0.0022989712,0.0029027546],"study_design_scores_gemma":[0.0025362733,0.0005593517,0.0009448535,0.00012936558,0.00014247032,0.000041957246,0.00009936284,0.011195887,0.9499499,0.0005886727,0.033065725,0.0007461454],"about_ca_topic_score_codex":0.000024139761,"about_ca_topic_score_gemma":0.00001834332,"teacher_disagreement_score":0.0413523,"about_ca_system_score_codex":0.000027664397,"about_ca_system_score_gemma":0.0003730257,"threshold_uncertainty_score":0.7248108},"labels":[],"label_agreement":null},{"id":"W4393941511","doi":"10.1038/s41419-024-06534-8","title":"Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Calgary; University of Guelph; University of Ottawa","funders":"National Institute on Aging; University of California, San Francisco; University of California, San Diego; Canadian Institutes of Health Research; Parkinson Canada; Government of Canada; Parkinson's Foundation; Ottawa Hospital Research Institute; University of Ottawa; Michael J. Fox Foundation for Parkinson's Research","keywords":"Neurodegeneration; In vivo; Dopaminergic; Parkinson's disease; Biology; Loss function; In vitro; Cell biology; Neuroscience; Pharmacology; Chemistry; Disease; Gene; Phenotype; Medicine; Dopamine; Biochemistry; Internal medicine; Genetics","score_opus":0.014296655878950407,"score_gpt":0.26167298706641196,"score_spread":0.24737633118746155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393941511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9685414,0.030304683,0.00002034898,0.00016084335,0.00010119209,0.00019804745,0.0000487231,0.000045956753,0.0005787941],"genre_scores_gemma":[0.997469,0.00172594,0.00028592424,0.00010820142,0.00007546246,0.00002065603,0.000017502409,0.000010670613,0.000286646],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9994311,0.000016415885,0.000098324796,0.00024512198,0.00008970946,0.000119363685],"domain_scores_gemma":[0.999271,0.000013995606,0.000015552847,0.00007299803,0.000017436754,0.00060905365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000025127318,0.000102844264,0.0001268516,0.000054671116,0.000039477887,0.000019626243,0.00001567229,0.000029848876,0.000100221834],"category_scores_gemma":[0.000011772727,0.000077460296,0.000051543175,0.000052805775,0.000052473933,0.00003596524,0.00002120606,0.000041792577,0.000011531677],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045988294,0.004747297,0.3277249,0.008279798,0.00097533694,0.014345934,0.00067939516,0.000013983134,0.47826514,0.0044926265,0.006708288,0.14916846],"study_design_scores_gemma":[0.0045460924,0.0009578406,0.9283389,0.00039653908,0.0051109483,0.00020259855,0.0001470216,0.005195956,0.038380172,0.008716907,0.007607597,0.0003994209],"about_ca_topic_score_codex":0.000005487648,"about_ca_topic_score_gemma":3.8907185e-8,"teacher_disagreement_score":0.600614,"about_ca_system_score_codex":0.000011745344,"about_ca_system_score_gemma":0.000067918925,"threshold_uncertainty_score":0.31587392},"labels":[],"label_agreement":null},{"id":"W4394923975","doi":"10.1038/s41419-024-06663-0","title":"IRE1 signaling increases PERK expression during chronic ER stress","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; University of Galway; College of Engineering, Michigan State University; Canada Research Chairs; Government of Canada; Research Manitoba; Michigan State University","keywords":"Unfolded protein response; Signal transduction; Cell biology; Chronic stress; Expression (computer science); Cancer research; Biology; Endoplasmic reticulum; Endocrinology; Computer science","score_opus":0.00487437600929301,"score_gpt":0.2217422543265721,"score_spread":0.2168678783172791,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394923975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.944702,0.054025646,0.00010991032,0.000030988544,0.00009033719,0.00012370228,0.00016394911,0.000041737323,0.0007116949],"genre_scores_gemma":[0.9968571,0.0013597904,0.000046858626,0.000076608114,0.0004826332,0.00003869156,0.0002499328,0.000027776787,0.0008606113],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989928,0.000034356563,0.00013261274,0.0004601125,0.000119461976,0.00026065984],"domain_scores_gemma":[0.99902445,0.000014911967,0.000022579472,0.00024783213,0.000021843493,0.00066835876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000031917483,0.00018588146,0.00010075126,0.000040443916,0.00013623621,0.00010942779,0.00008906615,0.00006410027,0.0000967488],"category_scores_gemma":[0.00004794406,0.00015663332,0.000107090644,0.00003906116,0.000051223364,0.000009646857,0.00012185863,0.000065876266,0.000014688652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003979286,0.00023203016,0.050992213,0.0018529299,0.0000388126,0.00053409056,0.000041352818,0.00043876658,0.94240695,0.00013568136,0.0020368053,0.0008924575],"study_design_scores_gemma":[0.0021426247,0.00020873503,0.03276385,0.0009765454,0.00033934528,0.000021110252,0.00019615014,0.0020965275,0.9514241,0.00041171012,0.008405764,0.001013543],"about_ca_topic_score_codex":0.00001568735,"about_ca_topic_score_gemma":0.00000159557,"teacher_disagreement_score":0.052665856,"about_ca_system_score_codex":0.000014212282,"about_ca_system_score_gemma":0.00017304874,"threshold_uncertainty_score":0.63873214},"labels":[],"label_agreement":null},{"id":"W4396546645","doi":"10.1038/s41419-024-06703-9","title":"Modeling acute myocardial infarction and cardiac fibrosis using human induced pluripotent stem cell-derived multi-cellular heart organoids","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nexen (Canada)","funders":"Ministry of Science and ICT, South Korea; Ministry of Food and Drug Safety; National Research Foundation","keywords":"Organoid; Induced pluripotent stem cell; Myocardial infarction; Stem cell; Cardiac fibrosis; Cardiology; Medicine; Mammalian heart; Fibrosis; Cell biology; Cancer research; Internal medicine; Biology; Embryonic stem cell","score_opus":0.0289516725860826,"score_gpt":0.2670162842430184,"score_spread":0.23806461165693577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396546645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9802665,0.015800279,0.002569643,0.000103042665,0.00048010537,0.00051654887,0.00006573155,0.00014248442,0.000055645978],"genre_scores_gemma":[0.99750423,0.0006518447,0.00089358387,0.00012345356,0.00045812974,0.000015380985,0.00009313081,0.000071679875,0.00018853278],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9983277,0.000062708335,0.00032205667,0.0006327264,0.000284943,0.00036988952],"domain_scores_gemma":[0.9986709,0.000018447134,0.0000300894,0.00028756357,0.000085164706,0.00090783305],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014119067,0.00031766255,0.00047639018,0.00017463606,0.00032903466,0.00020547502,0.0000360314,0.00015823655,0.000007397459],"category_scores_gemma":[0.0000068067266,0.000279705,0.00035149395,0.00014810268,0.00004161304,0.00016885143,0.00011065694,0.00025852854,0.000007289139],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014504035,0.00007519893,0.006128874,0.0005906753,0.00014225455,0.000039207338,0.00034954448,0.0017847999,0.99015385,0.00001176911,0.000046856985,0.0005319137],"study_design_scores_gemma":[0.003216774,0.00024741833,0.011557759,0.0007027708,0.00447463,0.000023769693,0.0007917873,0.9320417,0.045617916,0.0000519969,0.0004027413,0.0008707212],"about_ca_topic_score_codex":0.000162158,"about_ca_topic_score_gemma":2.9057676e-7,"teacher_disagreement_score":0.944536,"about_ca_system_score_codex":0.000091581736,"about_ca_system_score_gemma":0.00019808565,"threshold_uncertainty_score":0.9999655},"labels":[],"label_agreement":null},{"id":"W4399532434","doi":"10.1038/s41419-024-06739-x","title":"Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"Ontario Genomics Institute; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Genomics; Genome Canada; McGill University; Genentech; Bayer; Pfizer; Deutsche Forschungsgemeinschaft; Bristol-Myers Squibb","keywords":"Mutant; Mutation; Cancer; Cancer research; Cell biology; Biology; Genetics; Computational biology; Chemistry; Gene","score_opus":0.020194765288989027,"score_gpt":0.2925655852477765,"score_spread":0.2723708199587875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399532434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98999435,0.0070440522,0.0013594072,0.00048483166,0.000045168497,0.0005505941,0.00037867995,0.000016792143,0.00012614956],"genre_scores_gemma":[0.99910754,0.00014458394,0.0003494406,0.0000368392,0.000021092614,0.00015132967,0.00011910323,0.000013378806,0.000056676105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946564,0.000009560343,0.00018399846,0.0001656806,0.0000813073,0.000093837276],"domain_scores_gemma":[0.9994587,0.00013358815,0.00006565045,0.000099733705,0.00009010153,0.00015225179],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000051986528,0.00008413778,0.00011036707,0.000053110765,0.00012429319,0.0000115270195,0.000024934277,0.000030330675,0.000010356274],"category_scores_gemma":[0.000115706716,0.00006213804,0.0000360784,0.0001310058,0.00003336554,0.00005325544,0.000016638194,0.000057287358,1.4446299e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030145328,0.00008564313,0.015648825,0.0016091744,0.00021045687,0.0000024350236,0.002780205,0.00006741089,0.9287291,0.002045668,0.00026754942,0.048252072],"study_design_scores_gemma":[0.001863407,0.00011255627,0.27501506,0.000609142,0.001409326,0.0000085547335,0.0008922959,0.011188996,0.7058471,0.0009816869,0.0017895553,0.0002823311],"about_ca_topic_score_codex":0.000065818764,"about_ca_topic_score_gemma":0.00000894764,"teacher_disagreement_score":0.2593662,"about_ca_system_score_codex":0.000069117115,"about_ca_system_score_gemma":0.0004484736,"threshold_uncertainty_score":0.25339156},"labels":[],"label_agreement":null},{"id":"W4399704243","doi":"10.1038/s41419-024-06814-3","title":"Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Cancer Institute; Hollings Cancer Center, Medical University of South Carolina; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; National Institutes of Health; Medical University of South Carolina; National Institute of General Medical Sciences; Centre National de la Recherche Scientifique; University of South Carolina; National Center for Research Resources; Susan G. Komen; American Cancer Society; Foundation for the National Institutes of Health","keywords":"Tamoxifen; Breast cancer; Cancer research; Estrogen receptor; Phosphodiesterase; Cancer; Medicine; Biology; Pharmacology; Internal medicine; Biochemistry; Enzyme","score_opus":0.006379233497397721,"score_gpt":0.2549471747691335,"score_spread":0.24856794127173576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399704243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9130662,0.08434273,0.0006247515,0.00066717074,0.00011984546,0.0002858355,0.00031230092,0.000028573217,0.0005526005],"genre_scores_gemma":[0.98915756,0.008809348,0.00015424943,0.00019251528,0.00014850647,0.00007705948,0.00008822335,0.000037673446,0.0013348812],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987196,0.000055099714,0.00015174068,0.0005707936,0.00015459672,0.00034818734],"domain_scores_gemma":[0.99929166,0.000021197862,0.000024408031,0.00020669028,0.000043641772,0.00041240716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112667185,0.00019170217,0.0001435586,0.000089827685,0.00008437483,0.000104225925,0.00009777793,0.00011715648,0.000062875515],"category_scores_gemma":[0.000063596985,0.0001809085,0.000055853445,0.00014564773,0.00006480744,0.000012472438,0.00015735546,0.0001612715,0.00000408241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011817815,0.00013426112,0.009995495,0.0010820111,0.000098402925,0.0002491496,0.00025128838,0.00025715935,0.9768538,0.00032358806,0.005608352,0.0039647473],"study_design_scores_gemma":[0.007804983,0.00052013574,0.093899295,0.0022384848,0.00058134313,0.000055464116,0.00084334204,0.014281822,0.7107953,0.007809996,0.15710172,0.0040681125],"about_ca_topic_score_codex":0.00014219902,"about_ca_topic_score_gemma":0.00007911171,"teacher_disagreement_score":0.26605847,"about_ca_system_score_codex":0.000045896442,"about_ca_system_score_gemma":0.00026459858,"threshold_uncertainty_score":0.7377234},"labels":[],"label_agreement":null},{"id":"W4399918549","doi":"10.1038/s41419-024-06822-3","title":"Mechano-inhibition of endocytosis sensitizes cancer cells to Fas-induced Apoptosis","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Division of Molecular and Cellular Biosciences; National Heart, Lung, and Blood Institute; Pelotonia; Ohio State University; National Cancer Institute; National Institutes of Health; National Science Foundation; U.S. Department of Health and Human Services; Yale University; National Institute of General Medical Sciences; American Heart Association","keywords":"Endocytosis; Apoptosis; Cell biology; Cancer cell; Chemistry; Cancer research; Cancer; Biology; Cell; Biochemistry; Genetics","score_opus":0.009992021954617658,"score_gpt":0.24141257290716753,"score_spread":0.23142055095254987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399918549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937658,0.002486831,0.0025337152,0.00016383677,0.00029630784,0.00023164897,0.000119799704,0.000022026428,0.00038009003],"genre_scores_gemma":[0.9975307,0.0009003961,0.0002847094,0.00022372576,0.00018282783,0.00003519591,0.000096792595,0.000021128611,0.00072453846],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920994,0.000023550989,0.0001411925,0.00034866732,0.00010779828,0.0001688747],"domain_scores_gemma":[0.9994132,0.00000811713,0.000027305467,0.00017167027,0.00004904267,0.00033065156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055409182,0.00013945281,0.00011423829,0.00007000157,0.000053063293,0.000033538516,0.00003512036,0.00007682199,0.0000394319],"category_scores_gemma":[0.000010576116,0.00012460022,0.00009499814,0.00008420114,0.000013119845,0.000004987917,0.000057445952,0.0000337442,0.000008289583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084754676,0.000034245164,0.000040395407,0.00018187457,0.000017591712,0.0000063317116,0.000040160714,0.00006408609,0.9934059,0.00032568228,0.0008383026,0.0049607093],"study_design_scores_gemma":[0.00022033099,0.00010911531,0.00023281308,0.00006181856,0.00009462324,8.61719e-7,0.000033115823,0.000573456,0.9956943,0.0003359261,0.002480685,0.00016298318],"about_ca_topic_score_codex":0.000044401564,"about_ca_topic_score_gemma":0.0000049386977,"teacher_disagreement_score":0.0047977264,"about_ca_system_score_codex":0.00001129186,"about_ca_system_score_gemma":0.00008613577,"threshold_uncertainty_score":0.508105},"labels":[],"label_agreement":null},{"id":"W4400603495","doi":"10.1038/s41419-024-06891-4","title":"The eEF2 kinase coordinates the DNA damage response to cisplatin by supporting p53 activation","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; Terry Fox Research Institute; Spinal Cord Injury BC; University of British Columbia","funders":"Canadian Institutes of Health Research; Heinrich-Heine-Universität Düsseldorf; Deutsche Forschungsgemeinschaft; Deutsche Krebshilfe; Cancer Research UK","keywords":"DNA damage; Cisplatin; Cell biology; DNA repair; Biology; DNA; Genetics","score_opus":0.005360063104928546,"score_gpt":0.24344486268082108,"score_spread":0.23808479957589254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400603495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952239,0.0013087587,0.00064213265,0.0019226455,0.00009063922,0.00024138096,0.000050022114,0.000026815585,0.00049370603],"genre_scores_gemma":[0.9939524,0.000037880418,0.00004660029,0.0006285357,0.000068661124,0.00004745888,0.00007912832,0.000018312136,0.0051210145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992248,0.000096577285,0.00011413436,0.00027033946,0.00009230664,0.00020187709],"domain_scores_gemma":[0.9993143,0.00009848266,0.000027692342,0.00028905924,0.000025880752,0.00024455934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037402846,0.000111694826,0.000050266077,0.000017186812,0.00022821622,0.00014688051,0.00012518057,0.00004155299,0.000013507727],"category_scores_gemma":[0.00043219328,0.000068874324,0.00005069169,0.000067420704,0.000034013592,0.000005422224,0.00010947815,0.00005766565,0.000014312565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00061085785,0.000020981366,0.00020027196,0.00002643624,0.000010095156,0.000017676808,0.000057727706,0.000005624811,0.97869104,0.0002524545,0.017192638,0.0029141842],"study_design_scores_gemma":[0.00026040894,0.00017505304,0.0019325007,0.000026429807,0.000045663397,0.0000019730344,0.00024711332,0.0010420337,0.8459793,0.0009035843,0.14919245,0.00019352723],"about_ca_topic_score_codex":0.000005585753,"about_ca_topic_score_gemma":0.0000012191842,"teacher_disagreement_score":0.1327118,"about_ca_system_score_codex":0.000009192194,"about_ca_system_score_gemma":0.00009455423,"threshold_uncertainty_score":0.28086135},"labels":[],"label_agreement":null},{"id":"W4400786995","doi":"10.1038/s41419-024-06893-2","title":"Targeting valine catabolism to inhibit metabolic reprogramming in prostate cancer","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Queensland University of Technology; Australian Government","keywords":"Lipogenesis; Prostate cancer; LNCaP; Catabolism; Biology; Biochemistry; Downregulation and upregulation; Valine; Lipid metabolism; Metabolism; Chemistry; Cell biology; Cancer research; Cancer; Amino acid","score_opus":0.007845208853114268,"score_gpt":0.26076832846603193,"score_spread":0.25292311961291764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400786995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7414759,0.2568455,0.00011538915,0.00024806467,0.00069701474,0.00031238573,0.00011330999,0.00002769742,0.0001647742],"genre_scores_gemma":[0.9787551,0.015862763,0.00037852922,0.00076445733,0.0017333018,0.00021617682,0.00018425245,0.0000389149,0.0020665135],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99874395,0.000029445342,0.00019943799,0.0005678977,0.0001026028,0.0003566696],"domain_scores_gemma":[0.99918467,0.0000058516375,0.00002425379,0.00022076887,0.000037897447,0.0005265305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015998702,0.00017960717,0.00016659773,0.000089692105,0.00005633338,0.00008485886,0.000078716796,0.00004958036,0.000017245466],"category_scores_gemma":[0.00008143707,0.00016664807,0.00006948372,0.00018153389,0.00002769255,0.000008980358,0.000109632354,0.000090226014,0.0000090537615],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009393021,0.000330003,0.033588298,0.0011354773,0.00009667228,0.00016771817,0.0015978257,0.0017208995,0.72538435,0.00089649286,0.0256905,0.20845246],"study_design_scores_gemma":[0.00063479564,0.000028060811,0.005475543,0.000070202936,0.000098683384,0.0000027126898,0.00007808342,0.00031382556,0.021246122,0.00016686427,0.97153527,0.00034981643],"about_ca_topic_score_codex":0.00029913246,"about_ca_topic_score_gemma":0.000050367147,"teacher_disagreement_score":0.94584477,"about_ca_system_score_codex":0.00000866418,"about_ca_system_score_gemma":0.00023924932,"threshold_uncertainty_score":0.6795711},"labels":[],"label_agreement":null},{"id":"W4401061468","doi":"10.1038/s41419-024-06925-x","title":"Peroxisomal cholesterol metabolism regulates yap-signaling, which maintains intestinal epithelial barrier function and is altered in Crohn’s disease","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Dalhousie University; University of Toronto; University of Alberta; Hospital for Sick Children; Izaak Walton Killam Health Centre","funders":"CIHR Skin Research Training Centre; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Cell biology; Peroxisome; Intestinal epithelium; Signal transduction; Intestinal mucosa; Homeostasis; Inflammatory bowel disease; Intestinal Disorder; Cell signaling; Barrier function; Lipid metabolism; Epithelium; Disease; Receptor; Endocrinology; Internal medicine; Biochemistry; Medicine; Genetics","score_opus":0.008200480103554461,"score_gpt":0.22346142300353683,"score_spread":0.21526094289998238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401061468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863633,0.012023101,0.00064176804,0.00016348761,0.00021252867,0.00021098001,0.0002345156,0.000037704183,0.00011263269],"genre_scores_gemma":[0.9975469,0.00025083017,0.00009189016,0.000573692,0.0005002145,0.000044848857,0.00019648139,0.000036982805,0.00075814134],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985435,0.00008599917,0.00022904352,0.00066982384,0.00013664331,0.00033499085],"domain_scores_gemma":[0.9987804,0.000018341667,0.000034884608,0.00025561792,0.00005684989,0.0008538941],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016522514,0.00026725867,0.00017051748,0.00010695933,0.00011818541,0.00016990745,0.00008937648,0.000101831356,0.000058099824],"category_scores_gemma":[0.00010659215,0.00024249553,0.000091037655,0.00010070761,0.00008333706,0.000017729848,0.000090113426,0.00014717647,0.000012176746],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018565574,0.00022463391,0.05327753,0.00054822257,0.00006749979,0.00024628226,0.0003754114,0.000103279985,0.93773323,0.00039546602,0.00036725448,0.004804648],"study_design_scores_gemma":[0.0059733386,0.00065036904,0.7778079,0.00076630496,0.0011738839,0.000052998337,0.00038207404,0.014834789,0.15847471,0.013589159,0.02416883,0.002125661],"about_ca_topic_score_codex":0.000028141203,"about_ca_topic_score_gemma":0.0000097097645,"teacher_disagreement_score":0.7792585,"about_ca_system_score_codex":0.000011170781,"about_ca_system_score_gemma":0.00023152705,"threshold_uncertainty_score":0.98886806},"labels":[],"label_agreement":null},{"id":"W4401425262","doi":"10.1038/s41419-024-06964-4","title":"Regulation of Zfp36 by ISGF3 and MK2 restricts the expression of inflammatory cytokines during necroptosis stimulation","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Necroptosis; Downregulation and upregulation; Cell biology; MAPK/ERK pathway; Chemokine; Proinflammatory cytokine; Signal transduction; Tumor necrosis factor alpha; Cytokine; Chemistry; Cancer research; Biology; Programmed cell death; Inflammation; Immunology; Apoptosis; Biochemistry","score_opus":0.00602485591900225,"score_gpt":0.21272932732054892,"score_spread":0.20670447140154666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401425262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9727677,0.026751883,0.000041822255,0.000051412237,0.0000873401,0.00011308266,0.0000304651,0.000017784669,0.00013852185],"genre_scores_gemma":[0.99820894,0.0005312402,0.000005902646,0.000010759905,0.000008897206,0.0000054771667,0.000036906175,0.0000066043367,0.0011852989],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951226,0.0000862819,0.00016498799,0.0001250048,0.000024258292,0.000087193366],"domain_scores_gemma":[0.9996631,0.000108799024,0.000051962,0.00012129266,0.000027044474,0.000027779983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006145257,0.00007956119,0.00009547486,0.00006513356,0.000081134494,0.000012104134,0.000041451647,0.000060252023,0.000059492955],"category_scores_gemma":[0.000057542067,0.0000536321,0.00003354465,0.000045580426,0.000099707664,0.000077975696,0.00004602172,0.000057476227,0.000004036517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078336406,0.000023937708,0.007863814,0.0002454225,0.000012086806,0.0000011333063,0.00021864785,0.000011185503,0.9891722,0.00017614666,0.0008600326,0.0006320034],"study_design_scores_gemma":[0.00047973308,0.000054688164,0.21185836,0.00015730047,0.00005468964,0.00000238806,0.000078567704,0.000086623586,0.7851175,0.0001289741,0.0019142143,0.0000669409],"about_ca_topic_score_codex":0.000011091372,"about_ca_topic_score_gemma":1.8400374e-7,"teacher_disagreement_score":0.2040547,"about_ca_system_score_codex":0.000005692162,"about_ca_system_score_gemma":0.000032639637,"threshold_uncertainty_score":0.21870534},"labels":[],"label_agreement":null},{"id":"W4401614072","doi":"10.1038/s41419-024-06971-5","title":"Astrocytes and the tumor microenvironment inflammatory state dictate the killing of glioblastoma cells by Smac mimetic compounds","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; Institute of Infection and Immunity; University of Ottawa","funders":"Government of Canada; Canadian Institutes of Health Research; University of Ottawa","keywords":"Microglia; Programmed cell death; Stromal cell; Tumor microenvironment; Cancer research; Immune system; Astrocyte; Tumor necrosis factor alpha; Biology; Cancer cell; Cell biology; Inflammation; Immunology; Apoptosis; Cancer; Neuroscience; Central nervous system","score_opus":0.0029152884346460694,"score_gpt":0.18034298023765669,"score_spread":0.17742769180301063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401614072","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81780565,0.18112236,0.00005994352,0.00015240171,0.0003393315,0.0002517731,0.00011079861,0.000023067822,0.00013468495],"genre_scores_gemma":[0.99402785,0.0037211122,0.000012022259,0.00024934413,0.00001548755,0.000032927906,0.000019358136,0.000020693959,0.001901218],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901044,0.00016613647,0.000248893,0.00026180627,0.000043645607,0.00026908005],"domain_scores_gemma":[0.99926466,0.00032835465,0.00007486574,0.00025644392,0.000011021797,0.00006463495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020423629,0.00018932713,0.00019475436,0.000037389407,0.00019563385,0.000046084788,0.00016254716,0.0000360009,0.00008215878],"category_scores_gemma":[0.000009712659,0.00010948674,0.000079193145,0.00004584591,0.0009532464,0.000044678945,0.00014758753,0.0002071198,0.000052967996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024869388,0.00014180948,0.0040073437,0.0007495944,0.00031014803,0.000057997717,0.0023275372,0.00007658754,0.97433776,0.00026497076,0.012225447,0.0030138507],"study_design_scores_gemma":[0.004146517,0.00020728157,0.0030640673,0.00022141427,0.0006116147,0.000030455723,0.0005630055,0.0005249021,0.8696688,0.0007347285,0.11982242,0.00040481845],"about_ca_topic_score_codex":0.000021871047,"about_ca_topic_score_gemma":0.0000011372514,"teacher_disagreement_score":0.17740124,"about_ca_system_score_codex":0.000021001068,"about_ca_system_score_gemma":0.000057376874,"threshold_uncertainty_score":0.44647396},"labels":[],"label_agreement":null},{"id":"W4402489635","doi":"10.1038/s41419-024-07052-3","title":"The NRF2-CARM1 axis links glucose sensing to transcriptional and epigenetic regulation of the pentose phosphate pathway in gastric cancer","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; Anhui Medical University; Leukemia and Lymphoma Society of Canada","keywords":"Pentose phosphate pathway; Biology; Nicotinamide adenine dinucleotide phosphate; Cancer cell; Biochemistry; Cell growth; Cell biology; Cancer; Cancer research; Glycolysis; Metabolism; Enzyme; Oxidase test; Genetics","score_opus":0.00675225712768987,"score_gpt":0.2222991976032046,"score_spread":0.21554694047551473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402489635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9391398,0.05931041,0.00047016,0.00054905034,0.00018397694,0.0002509608,0.000041720697,0.0000046154905,0.00004931281],"genre_scores_gemma":[0.99714214,0.002129835,0.000038226004,0.0000830572,0.000096944656,0.000012694379,0.000026343901,0.000011376126,0.00045936328],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993511,0.00004204793,0.00014200583,0.00023286734,0.00010116335,0.00013084589],"domain_scores_gemma":[0.9996351,0.000014136546,0.000027753365,0.00015541726,0.00003530184,0.00013228126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009239245,0.00009328436,0.000061006955,0.000031781725,0.00008144458,0.000035242236,0.00004616386,0.00006966327,0.000006481648],"category_scores_gemma":[0.000023451475,0.00006570295,0.000048433212,0.00012842962,0.00005010246,0.000004265825,0.00003440081,0.00006590485,6.454719e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037789092,0.00002933392,0.0065009105,0.00013635425,0.000023675837,0.0000029159414,0.00020477718,0.0060805124,0.8886236,0.00012310568,0.00021189313,0.09768502],"study_design_scores_gemma":[0.0010720027,0.00011682797,0.6175831,0.00023270638,0.00012243354,0.000006883997,0.000059501053,0.018955547,0.34095642,0.0012472051,0.019353459,0.00029394808],"about_ca_topic_score_codex":0.00005199088,"about_ca_topic_score_gemma":0.00010318663,"teacher_disagreement_score":0.61108214,"about_ca_system_score_codex":0.000022253866,"about_ca_system_score_gemma":0.00016761498,"threshold_uncertainty_score":0.26792884},"labels":[],"label_agreement":null},{"id":"W4402496557","doi":"10.1038/s41419-024-07003-y","title":"Extracellular vesicle-associated DNA: ten years since its discovery in human blood","year":2024,"lang":"en","type":"review","venue":"Cell Death and Disease","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"McGill University","keywords":"Extracellular vesicles; Liquid biopsy; Extracellular vesicle; Computational biology; DNA; Biomarker; Biology; Isolation (microbiology); Bioinformatics; Microvesicles; Nanotechnology; microRNA; Cell biology; Cancer; Genetics; Gene","score_opus":0.01731649553924808,"score_gpt":0.2808162383322117,"score_spread":0.2634997427929636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402496557","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.055477567,0.9427729,0.0000063926873,0.000009316762,0.0001460541,0.00066341617,0.0005481445,0.000037660982,0.00033851594],"genre_scores_gemma":[0.05817746,0.9302285,0.000017872484,0.00004196826,0.00027671695,0.00012376865,0.0020094682,0.00015129424,0.00897296],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972806,0.00021164012,0.00059420126,0.001130491,0.00023472011,0.0005483229],"domain_scores_gemma":[0.9982928,0.000025180156,0.0002013745,0.0007149331,0.000030305398,0.00073541823],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022321835,0.0006171856,0.0007665413,0.00016594418,0.000082842555,0.00019597662,0.0004233658,0.00043677707,0.000015026825],"category_scores_gemma":[0.00017602643,0.00058950495,0.0005415879,0.00022866472,0.00010358736,0.000016431324,0.00040061824,0.00035672123,0.000060666152],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010801189,0.02513547,0.008754989,0.35403508,0.006305086,0.07252959,0.000482943,0.00007282271,0.12806864,0.016780963,0.035843216,0.35091108],"study_design_scores_gemma":[0.002185733,0.0002906478,0.00064189814,0.00985679,0.009772294,0.000031901112,0.00003380284,0.00004153017,0.0007973994,0.000794244,0.97279,0.0027637281],"about_ca_topic_score_codex":0.000007995331,"about_ca_topic_score_gemma":0.000005953258,"teacher_disagreement_score":0.9369468,"about_ca_system_score_codex":0.000058277146,"about_ca_system_score_gemma":0.0005557377,"threshold_uncertainty_score":0.99965566},"labels":[],"label_agreement":null},{"id":"W4402983075","doi":"10.1038/s41419-024-07046-1","title":"Deciphering the ghost proteome in ovarian cancer cells by deep proteogenomic characterization","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds Wetenschappelijk Onderzoek; Vlaamse regering; Institut National de la Santé et de la Recherche Médicale; Université de Lille","keywords":"Proteogenomics; Proteome; Proteomics; Biology; Computational biology; Transcriptome; Genomics; Genome; Bioinformatics; Genetics; Gene expression; Gene","score_opus":0.006694526125552072,"score_gpt":0.23753637481516693,"score_spread":0.23084184868961485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402983075","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95747346,0.0028992821,0.0363557,0.00062632473,0.0000362544,0.0009877796,0.0003330492,0.00014768414,0.001140466],"genre_scores_gemma":[0.9948695,0.00072404084,0.0009924625,0.00012749575,0.00009169655,0.002030827,0.00011317239,0.000030978794,0.0010198576],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934435,0.0000066935772,0.00014034945,0.00027637364,0.00005925858,0.00017300254],"domain_scores_gemma":[0.99958205,0.000014366576,0.000033340075,0.00019955623,0.000010729433,0.00015995053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000040665418,0.00012077189,0.00007467611,0.000019710815,0.00009623956,0.00009483874,0.00011105639,0.00004604828,0.00017602056],"category_scores_gemma":[0.000005546626,0.000095951465,0.000029934943,0.00008884956,0.000026852205,0.00008570206,0.00004773988,0.00013159007,0.0000092303235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025047333,0.000031988122,0.001137749,0.00022419877,0.0000032152586,0.0000072037055,0.00007812529,0.000025671981,0.99441946,0.00028218984,0.00003782386,0.003727309],"study_design_scores_gemma":[0.00034126936,0.000008556305,0.0013612934,0.00018888853,0.000046514717,0.0000015244248,0.000035916975,0.0119634755,0.95100653,0.0042929347,0.030376023,0.00037707292],"about_ca_topic_score_codex":0.00003993354,"about_ca_topic_score_gemma":0.00000287812,"teacher_disagreement_score":0.043412946,"about_ca_system_score_codex":0.000055296816,"about_ca_system_score_gemma":0.00006674505,"threshold_uncertainty_score":0.3912787},"labels":[],"label_agreement":null},{"id":"W4403318685","doi":"10.1038/s41419-024-07103-9","title":"High mitochondrial DNA content is a key determinant of stemness, proliferation, cell migration, and cancer metastasis in vivo","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Communications Research Centre Canada","funders":"University of Salford Manchester","keywords":"Biology; Mitochondrial DNA; Mitochondrion; Cell growth; Molecular biology; Cell cycle; Cancer cell; CD44; Cell; Cell biology; Cell culture; Cancer research; Cancer; Genetics; Gene","score_opus":0.015135381055786008,"score_gpt":0.2400335780109227,"score_spread":0.2248981969551367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403318685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98590785,0.01203609,0.0005810594,0.0002762541,0.00051938876,0.00030391238,0.00029084264,0.000007116736,0.00007745921],"genre_scores_gemma":[0.99470836,0.0021122831,0.00028328397,0.00036778854,0.00023742825,0.000098429766,0.00007566738,0.0000130182125,0.0021037695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918246,0.00005415485,0.00021570329,0.00034483455,0.000072460956,0.00013038417],"domain_scores_gemma":[0.9995532,0.00001157603,0.000042658834,0.00014380296,0.000060014332,0.00018877121],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000046758167,0.00013125013,0.00015097966,0.00005817981,0.000039251074,0.000036149337,0.00004065974,0.000078978715,0.000087290966],"category_scores_gemma":[0.000029181612,0.0001100497,0.00005190363,0.000057317266,0.000046090478,0.000008300437,0.000032769403,0.000042521075,0.0000018638028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006875421,0.000120785895,0.028494077,0.0004726777,0.0000227542,0.0000353183,0.00028368886,0.0000139569365,0.9605461,0.00017880961,0.0082833795,0.0008609519],"study_design_scores_gemma":[0.0021778373,0.00033842676,0.0055807997,0.00008153743,0.00022888886,0.000008225596,0.00011751101,0.00045853783,0.9292981,0.00026204597,0.06109648,0.00035159217],"about_ca_topic_score_codex":0.0001599172,"about_ca_topic_score_gemma":0.0001827096,"teacher_disagreement_score":0.052813098,"about_ca_system_score_codex":0.00000630863,"about_ca_system_score_gemma":0.00015866746,"threshold_uncertainty_score":0.4487697},"labels":[],"label_agreement":null},{"id":"W4403453927","doi":"10.1038/s41419-024-07133-3","title":"Loss of miR-200c-3p promotes resistance to radiation therapy via the DNA repair pathway in prostate cancer","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ligue Contre le Cancer; Fondation ARC pour la Recherche sur le Cancer; Institut National de la Santé et de la Recherche Médicale; Sunnybrook Research Institute","keywords":"Radioresistance; Prostate cancer; Cancer research; DNA methylation; DNA repair; Downregulation and upregulation; microRNA; DNA damage; Radiosensitivity; Biology; Radiation therapy; Cancer; Medicine; DNA; Gene expression; Gene; Internal medicine; Genetics","score_opus":0.006093579254594171,"score_gpt":0.23877696242981572,"score_spread":0.23268338317522155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403453927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90822434,0.09041096,0.000064498345,0.00041553588,0.00007143837,0.00046981213,0.00013427863,0.000018674431,0.0001904501],"genre_scores_gemma":[0.99638253,0.00160376,0.00007897608,0.00028375763,0.00008589942,0.00012947763,0.000060235394,0.000020962127,0.001354386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991509,0.00006264351,0.00016621908,0.00034076138,0.00010333502,0.00017618171],"domain_scores_gemma":[0.99938244,0.000015197267,0.000033954588,0.00031201137,0.00003323538,0.00022318403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013708745,0.00012523323,0.00008491827,0.000034289387,0.00004139188,0.000026700061,0.0001036074,0.000038488477,0.000012833441],"category_scores_gemma":[0.000050642524,0.00009375858,0.000074554526,0.00011657625,0.000060147013,0.0000065415875,0.000041861524,0.00005005638,0.0000031939212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023458789,0.00049456675,0.0975015,0.0010940002,0.00007700731,0.0002750431,0.00097131694,0.00018456577,0.8733524,0.00042553837,0.0061242436,0.017153943],"study_design_scores_gemma":[0.0016306115,0.00027496932,0.09245551,0.0002657694,0.000071242204,0.0000025613083,0.000080824255,0.001291911,0.7608864,0.0032218248,0.1391832,0.0006351918],"about_ca_topic_score_codex":0.000017764516,"about_ca_topic_score_gemma":0.00002846345,"teacher_disagreement_score":0.13305895,"about_ca_system_score_codex":0.000014973434,"about_ca_system_score_gemma":0.00021133122,"threshold_uncertainty_score":0.38233638},"labels":[],"label_agreement":null},{"id":"W4403757578","doi":"10.1038/s41419-024-07170-y","title":"One-carbon-mediated purine synthesis underlies temozolomide resistance in glioblastoma","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Temozolomide; Glioblastoma; Cancer research; Purine; Chemistry; Biology; Biochemistry; Enzyme","score_opus":0.008353819908123774,"score_gpt":0.21781025511629024,"score_spread":0.20945643520816645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403757578","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93316704,0.06287862,0.000067168185,0.00035009164,0.000056233766,0.00009490642,0.000032288186,0.000029529328,0.003324091],"genre_scores_gemma":[0.99680257,0.001196236,0.00011820848,0.00014124162,0.00015758279,0.000033281216,0.00003095706,0.000020942196,0.0014989885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999194,0.000033460645,0.00014293128,0.00034068336,0.000083342595,0.0002055546],"domain_scores_gemma":[0.99949205,0.000056459598,0.000018924411,0.00017731873,0.000015476196,0.00023979797],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000069726564,0.0001324636,0.000111935486,0.00006908654,0.000033572327,0.000042318676,0.0000765283,0.00006758821,0.000023367524],"category_scores_gemma":[0.00013293224,0.00013023565,0.000047835976,0.00010285867,0.000042677362,0.0000043317436,0.000056492478,0.00006350668,0.000008610216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010957575,0.0021910372,0.16613854,0.007804239,0.0006285831,0.005009669,0.0006892815,0.00045842704,0.69054216,0.006508313,0.09863095,0.010441199],"study_design_scores_gemma":[0.006849704,0.0012008131,0.099144205,0.0028248283,0.0012327248,0.00003957849,0.0008034419,0.008009968,0.5583072,0.021640815,0.29463693,0.005309826],"about_ca_topic_score_codex":0.000012169456,"about_ca_topic_score_gemma":0.000020664816,"teacher_disagreement_score":0.19600599,"about_ca_system_score_codex":0.0000101303385,"about_ca_system_score_gemma":0.000121427234,"threshold_uncertainty_score":0.5310856},"labels":[],"label_agreement":null},{"id":"W4403971668","doi":"10.1038/s41419-024-07127-1","title":"Inhibition of mitochondrial OMA1 ameliorates osteosarcoma tumorigenesis","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Science Foundation of Guangdong Province; Guangzhou Medical University","keywords":"Carcinogenesis; Osteosarcoma; Cancer research; Mitochondrion; Biology; Chemistry; Cell biology; Cancer; Genetics","score_opus":0.0069218331215522315,"score_gpt":0.22692679649690195,"score_spread":0.22000496337534972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403971668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9518108,0.04598435,0.00024468626,0.00004440121,0.0009712685,0.00012642938,0.00013862827,0.000015724909,0.0006637072],"genre_scores_gemma":[0.9949351,0.0021712189,0.00017838494,0.00010361637,0.0015405929,0.000021993867,0.00018177672,0.00001607512,0.00085127115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937546,0.00002146415,0.00012455235,0.00026317377,0.00007832037,0.00013699949],"domain_scores_gemma":[0.99952304,0.0000068845898,0.000024548894,0.00016018515,0.000036195488,0.00024914453],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003111602,0.000109433924,0.00010232438,0.00004418566,0.00003679806,0.00003152047,0.000040478895,0.00005185604,0.00002369554],"category_scores_gemma":[0.00002795249,0.00009945228,0.00009150042,0.00006526528,0.000048757924,0.000004961917,0.000041069976,0.000031104206,0.0000073936035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022559805,0.00006111212,0.00071192946,0.00023063332,0.00001538103,0.000012885419,0.000037855938,0.000004499257,0.9881539,0.00019456737,0.0063866433,0.003965016],"study_design_scores_gemma":[0.0012205926,0.00021131348,0.0048246137,0.000078363344,0.0002550359,0.00000824773,0.00008569634,0.000089262,0.79023296,0.0013339389,0.20128863,0.0003713547],"about_ca_topic_score_codex":0.00001726182,"about_ca_topic_score_gemma":0.0000033718895,"teacher_disagreement_score":0.19792092,"about_ca_system_score_codex":0.0000035264566,"about_ca_system_score_gemma":0.00015056094,"threshold_uncertainty_score":0.40555462},"labels":[],"label_agreement":null},{"id":"W4404639357","doi":"10.1038/s41419-024-07251-y","title":"Seratrodast inhibits ferroptosis by suppressing lipid peroxidation","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lipid peroxidation; Necroptosis; Pharmacology; Programmed cell death; Apoptosis; Oxidative stress; GPX4; Chemistry; Drug; Cancer research; Medicine; Biochemistry; Superoxide dismutase","score_opus":0.012773217855217824,"score_gpt":0.2543597511424259,"score_spread":0.2415865332872081,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404639357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97553116,0.018697228,0.00020844254,0.001924114,0.00016043022,0.00021231663,0.00007209732,0.00013058844,0.003063609],"genre_scores_gemma":[0.9957682,0.0008202042,0.00011569985,0.00083523564,0.0002823017,0.000043389922,0.00018585521,0.00002716055,0.0019219375],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911904,0.00001967079,0.00014010111,0.0003465071,0.00016954605,0.00020514094],"domain_scores_gemma":[0.9991529,0.000017093082,0.000017079008,0.00015223691,0.00003550062,0.000625193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005332663,0.00014667014,0.00014330263,0.000062907086,0.000101477184,0.00016595543,0.00003115253,0.000048016413,0.00029955644],"category_scores_gemma":[0.000023033665,0.00012041949,0.000081318394,0.00011649218,0.000032654287,0.00015766182,0.000030408462,0.00010471326,0.000045858924],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012877468,0.0012275984,0.21279864,0.0065991334,0.00017444226,0.00021633654,0.0010268873,0.000014446998,0.2945458,0.00067910843,0.36310565,0.118324205],"study_design_scores_gemma":[0.0068261153,0.0012292215,0.10266743,0.003387985,0.0036427353,0.000056221423,0.00087630755,0.0217465,0.4376918,0.0005970847,0.41930413,0.0019744646],"about_ca_topic_score_codex":0.00001040915,"about_ca_topic_score_gemma":3.505236e-7,"teacher_disagreement_score":0.143146,"about_ca_system_score_codex":0.00003467333,"about_ca_system_score_gemma":0.00013114714,"threshold_uncertainty_score":0.49105644},"labels":[],"label_agreement":null},{"id":"W4404794254","doi":"10.1038/s41419-024-07247-8","title":"Blood matters: the hematological signatures of Coronavirus infection","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Ottawa","funders":"Fondo para la Investigación Científica y Tecnológica; Agencia Nacional de Promoción Científica y Tecnológica; Natural Sciences and Engineering Research Council of Canada; Alliance de recherche numérique du Canada; Institut Pasteur de Montevideo; Universidad de la República Uruguay; Universidad Nacional de Quilmes; Ministerio de Ciencia, Tecnología e Innovación Productiva; University of Ottawa","keywords":"Heme; Coronavirus; Biology; Virus; Hemin; Virology; Cell biology; Computational biology; Disease; Coronavirus disease 2019 (COVID-19); Medicine; Biochemistry; Infectious disease (medical specialty)","score_opus":0.04666086042735212,"score_gpt":0.3916239142485577,"score_spread":0.34496305382120557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404794254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738136,0.015673028,0.00014544575,0.009200589,0.0000876564,0.00033394428,0.000025049862,0.00006827582,0.0006524129],"genre_scores_gemma":[0.9955501,0.0014719998,0.00001397329,0.0024506473,0.00006534403,0.000020994199,0.000005506003,0.000005438331,0.00041600302],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993723,0.000034439017,0.00012197909,0.00017201478,0.00017369058,0.00012555187],"domain_scores_gemma":[0.9981455,0.0013964322,0.0000143250145,0.00013779123,0.000031682524,0.00027426952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012946305,0.000072453826,0.0001364335,0.00003275231,0.000050153463,0.000018541237,0.000033667817,0.000034478675,0.000114350354],"category_scores_gemma":[0.002210499,0.000037762708,0.0000904169,0.00007959501,0.00015022355,0.000023357652,0.000076207616,0.00015957752,0.000018660927],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030150977,0.0033070238,0.88643754,0.022839764,0.0006665996,0.003573443,0.00056166656,0.00006564246,0.010208125,0.011916276,0.028834555,0.028574282],"study_design_scores_gemma":[0.0021908856,0.0010339633,0.9181903,0.00064117694,0.0015660198,0.000007701753,0.000048046437,0.0023086432,0.0019552733,0.011962512,0.05985729,0.00023820181],"about_ca_topic_score_codex":0.0000361401,"about_ca_topic_score_gemma":8.155737e-7,"teacher_disagreement_score":0.03175276,"about_ca_system_score_codex":0.000008193757,"about_ca_system_score_gemma":0.000110487745,"threshold_uncertainty_score":0.26463336},"labels":[],"label_agreement":null},{"id":"W4405237221","doi":"10.1038/s41419-024-07256-7","title":"Correction: NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90","year":2024,"lang":"en","type":"erratum","venue":"Cell Death and Disease","topic":"Cancer Research and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Myosin; Cell biology; Hsp90; Chemistry; Biochemistry; Biology; Gene","score_opus":0.00885324107332203,"score_gpt":0.24920206171098963,"score_spread":0.2403488206376676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405237221","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14685033,0.75462264,0.00009156247,0.003281117,0.009518013,0.0033928754,0.0015567688,0.00040627376,0.08028043],"genre_scores_gemma":[0.23650743,0.023450121,0.00007159589,0.0003184095,0.00094199984,0.00017879669,0.0030287148,0.00010987709,0.73539305],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99847347,0.000029863075,0.00017076128,0.00063294236,0.00035917925,0.0003338102],"domain_scores_gemma":[0.9982957,0.0000428484,0.00005969347,0.00030197433,0.00006773207,0.0012320515],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000053667027,0.00034515778,0.00034201276,0.00012713627,0.00014240677,0.00018342414,0.000038196493,0.00014636565,0.00012471978],"category_scores_gemma":[0.000022455359,0.00025178987,0.000082332874,0.00012970899,0.000107082975,0.0000764651,0.000036439185,0.00043267125,0.000019444466],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010200569,0.00027620702,0.002988108,0.0024440815,0.00007289024,0.00047837908,0.00021114718,8.201135e-7,0.00009091461,0.000003020014,0.99068326,0.0017311183],"study_design_scores_gemma":[0.0029602346,0.0015675542,0.0037720723,0.0017252596,0.0019057062,0.00005229383,0.00030037062,0.0014070862,0.0009634578,0.00016556759,0.98461795,0.0005624775],"about_ca_topic_score_codex":0.0004072156,"about_ca_topic_score_gemma":0.0001336688,"teacher_disagreement_score":0.7311725,"about_ca_system_score_codex":0.00015086062,"about_ca_system_score_gemma":0.0008737963,"threshold_uncertainty_score":0.99999344},"labels":[],"label_agreement":null},{"id":"W4405510703","doi":"10.1038/s41419-024-07288-z","title":"CPNE7 promotes colorectal tumorigenesis by interacting with NONO to initiate ZFP42 transcription","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Key Research and Development Program of China; Natural Science Foundation of Henan Province; National Natural Science Foundation of China","keywords":"Carcinogenesis; Gene knockdown; Colorectal cancer; Cancer research; Metastasis; Biology; Downregulation and upregulation; Cell growth; Small hairpin RNA; Transcription factor; Apoptosis; Cancer; Gene; Genetics","score_opus":0.007672421356663145,"score_gpt":0.23568133771376765,"score_spread":0.2280089163571045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405510703","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991059,0.0034459138,0.0041395514,0.00015765478,0.0000930604,0.00018704066,0.00009434462,0.00001890436,0.0008045294],"genre_scores_gemma":[0.99842435,0.00016930242,0.00014403778,0.00015896259,0.000087551656,0.00009865779,0.00015431443,0.00001579917,0.0007470211],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994622,0.000014258091,0.00007652051,0.00027254317,0.000050598745,0.00012388658],"domain_scores_gemma":[0.9996095,0.000005769335,0.000012770866,0.00009816248,0.000026713318,0.00024712132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000034800913,0.00009467675,0.000055065895,0.000024896763,0.00006381263,0.00007866246,0.000044335593,0.000026609032,0.000021711903],"category_scores_gemma":[0.000012519526,0.00007771488,0.000031078827,0.000056333032,0.000017378356,0.0000074200916,0.000013325281,0.000033337805,0.000009429963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038181452,0.00009184114,0.002736062,0.00013465247,0.000025430209,0.00002104972,0.0001559836,0.000022985774,0.9879936,0.000056007877,0.0026092653,0.0057713054],"study_design_scores_gemma":[0.0014050842,0.0016075856,0.015468457,0.0003170391,0.00037619032,0.000028061359,0.00048542276,0.0025592449,0.8384351,0.00030537462,0.13788462,0.0011278385],"about_ca_topic_score_codex":0.000017344026,"about_ca_topic_score_gemma":0.000005985176,"teacher_disagreement_score":0.14955851,"about_ca_system_score_codex":0.000009384561,"about_ca_system_score_gemma":0.00008602599,"threshold_uncertainty_score":0.3169121},"labels":[],"label_agreement":null},{"id":"W4405524971","doi":"10.1038/s41419-024-07289-y","title":"GPx1 deficiency confers increased susceptibility to ferroptosis in macrophages from individuals with active Crohn’s disease","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Indian Institute of Technology Bombay; Crohn's and Colitis Foundation; University of Calgary; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"Selenoprotein; GPX1; Programmed cell death; GPX4; Necroptosis; Immunology; Biology; Inflammation; Monocyte; Pyroptosis; Macrophage; Apoptosis; Cancer research; Inflammasome; Glutathione peroxidase; Oxidative stress; Superoxide dismutase; Endocrinology; Biochemistry","score_opus":0.01442816986930944,"score_gpt":0.26487892546465697,"score_spread":0.2504507555953475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405524971","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98967475,0.0057994532,0.000067281304,0.0009752712,0.000073042196,0.0009463359,0.0010360517,0.000109504086,0.0013183107],"genre_scores_gemma":[0.99739325,0.00026022698,0.00022728731,0.0013044946,0.000080792524,0.00025200984,0.00019052578,0.00003991263,0.00025151757],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979958,0.000077409095,0.00025630192,0.0008689505,0.0003759174,0.00042565019],"domain_scores_gemma":[0.99729383,0.000101792044,0.00003392637,0.00041468363,0.00006836129,0.002087405],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012050074,0.00031317602,0.00035874813,0.00023188743,0.000110600864,0.00018017452,0.00010852261,0.000061722116,0.0005826509],"category_scores_gemma":[0.0001291841,0.00023884936,0.00011352406,0.00046708627,0.00011860213,0.0001548697,0.000084726984,0.00019265962,0.0000417684],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040252176,0.0009198577,0.982171,0.000785545,0.000060331444,0.001226923,0.0007797848,0.00001723827,0.00083135447,0.00011921453,0.0013563356,0.007707227],"study_design_scores_gemma":[0.0016463081,0.00023126353,0.993596,0.0004475676,0.0005923083,0.0000010090129,0.00048723407,0.00026832242,0.0012987326,0.00033686834,0.0007671199,0.00032723046],"about_ca_topic_score_codex":0.0009628816,"about_ca_topic_score_gemma":0.00005994081,"teacher_disagreement_score":0.011425065,"about_ca_system_score_codex":0.00014404669,"about_ca_system_score_gemma":0.0007272592,"threshold_uncertainty_score":0.9739994},"labels":[],"label_agreement":null},{"id":"W4405525093","doi":"10.1038/s41419-024-07304-2","title":"DARPins as a novel tool to detect and degrade p73","year":2024,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Bundesministerium für Bildung und Forschung; Ontario Genomics Institute; Merck KGaA; Ontario Genomics; Genome Canada; Genentech; Bayer; Universität Zürich; Pfizer; Deutsche Forschungsgemeinschaft; Bristol-Myers Squibb","keywords":"Ankyrin repeat; Ubiquitin ligase; DNA ligase; Biology; Small molecule; Transcription factor; Protein–protein interaction; Plasma protein binding; Cell biology; DNA-binding protein; Signal transducing adaptor protein; Computational biology; Proximity ligation assay; Ubiquitin; Biochemistry; DNA; Signal transduction; Gene; Receptor","score_opus":0.008301515021582388,"score_gpt":0.23874307205286976,"score_spread":0.23044155703128738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405525093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835012,0.008978117,0.0038490011,0.0003794553,0.000112896974,0.00022366004,0.00006185414,0.000028769657,0.002865041],"genre_scores_gemma":[0.9938417,0.00029465827,0.00088769966,0.0011849179,0.00014580956,0.000029593084,0.000051396535,0.0000135145865,0.0035507109],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994306,0.000008611118,0.00007965078,0.00029062992,0.00006006595,0.00013044354],"domain_scores_gemma":[0.9994362,0.0000048427055,0.000008331973,0.00014213027,0.000013334814,0.00039518718],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000041267765,0.000100551166,0.000055604276,0.000034587894,0.000053495685,0.000080652164,0.000044469827,0.000044353495,0.000017575747],"category_scores_gemma":[0.00008414386,0.0000879986,0.00003599452,0.00004770283,0.000023085062,0.0000045410566,0.00006835556,0.000036925903,0.000022296974],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020527889,0.000055796627,0.0011344819,0.00024231177,0.000027133612,0.000050480063,0.000055545173,0.0000040226937,0.93908715,0.00143402,0.015643729,0.042060073],"study_design_scores_gemma":[0.00071669125,0.00031839983,0.005107257,0.00006153321,0.00006470652,0.000017927501,0.000033716493,0.00026004267,0.27711552,0.0009560423,0.71491843,0.00042969696],"about_ca_topic_score_codex":0.000009869305,"about_ca_topic_score_gemma":0.0000020105913,"teacher_disagreement_score":0.6992747,"about_ca_system_score_codex":0.000004731977,"about_ca_system_score_gemma":0.0000982394,"threshold_uncertainty_score":0.3588479},"labels":[],"label_agreement":null},{"id":"W4406100723","doi":"10.1038/s41419-024-07320-2","title":"Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ontario Genomics Institute; Merck KGaA; Ontario Genomics; Genome Canada; Genentech; Bayer; Pfizer; Deutsche Forschungsgemeinschaft; Bristol-Myers Squibb","keywords":"Gene isoform; Alternative splicing; Biology; Linker; RNA splicing; DNA; Cell biology; Transcription factor; DNA-binding domain; Amino acid; Plasma protein binding; Binding domain; DNA-binding protein; Transcription (linguistics); Binding site; Gene; Molecular biology; Biochemistry; RNA","score_opus":0.013205476129733596,"score_gpt":0.2564482106952377,"score_spread":0.2432427345655041,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406100723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956101,0.0019510774,0.0002900305,0.0005464352,0.00004290541,0.00038187622,0.000006151839,0.00000667309,0.001164751],"genre_scores_gemma":[0.99892825,0.00015613141,0.000056513007,0.00069774967,0.00002065041,0.000017370936,0.000009671186,0.000006715615,0.00010696268],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99942696,0.000031426112,0.00013662502,0.00019175583,0.00008337809,0.00012984364],"domain_scores_gemma":[0.99961257,0.000049749688,0.000027994363,0.00015296179,0.000017928625,0.00013880254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008892949,0.00008472989,0.00014380505,0.00019711691,0.00002272359,0.000012146125,0.000040340376,0.000034401797,0.0000016271073],"category_scores_gemma":[0.00010092218,0.000065312895,0.000028136958,0.00021159642,0.000025370286,0.000030291594,0.00003952409,0.000103875434,9.737201e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005691368,0.00078916026,0.18073554,0.0016518674,0.00008287135,0.002518345,0.009507163,0.0009803344,0.7710026,0.0018721463,0.0006425084,0.024526127],"study_design_scores_gemma":[0.01852539,0.0005517444,0.47219738,0.004578001,0.0007469976,0.000042451564,0.0032689027,0.030971238,0.457995,0.009259833,0.0010971919,0.0007658709],"about_ca_topic_score_codex":0.00018609856,"about_ca_topic_score_gemma":0.000010833338,"teacher_disagreement_score":0.31300756,"about_ca_system_score_codex":0.000038252296,"about_ca_system_score_gemma":0.00006691146,"threshold_uncertainty_score":0.26633826},"labels":[],"label_agreement":null},{"id":"W4407228542","doi":"10.1038/s41419-025-07387-5","title":"Inhibition of TFF3 synergizes with c-MET inhibitors to decrease the CSC-like phenotype and metastatic burden in ER+HER2+ mammary carcinoma","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Tsinghua Shenzhen International Graduate School; China Postdoctoral Science Foundation; Basic and Applied Basic Research Foundation of Guangdong Province; Shenzhen Bay Laboratory; Science, Technology and Innovation Commission of Shenzhen Municipality; National Natural Science Foundation of China","keywords":"Cancer research; Estrogen receptor; Cell growth; Phenotype; Metastasis; Biology; Signal transduction; Cancer; Medicine; Breast cancer; Internal medicine; Cell biology; Genetics","score_opus":0.008576987300867964,"score_gpt":0.23482712497970992,"score_spread":0.22625013767884194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407228542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987869,0.008937062,0.00011433407,0.00094930234,0.00005267148,0.0005469892,0.000042948435,0.00001269254,0.0014749992],"genre_scores_gemma":[0.99687296,0.0003539982,0.0006412877,0.0013986995,0.000036413676,0.000052442658,0.000031012405,0.000012187673,0.00060098816],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991178,0.000050941722,0.00020743419,0.0002807847,0.00015586804,0.00018719485],"domain_scores_gemma":[0.99889296,0.000073541945,0.00004783882,0.00026451988,0.00005659779,0.00066456076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013081024,0.0001591926,0.0002720094,0.00017027566,0.000052781845,0.000024969384,0.000041925636,0.000023828614,0.000031557393],"category_scores_gemma":[0.00009817942,0.00010418633,0.000047631278,0.00030451542,0.00007664749,0.00006234203,0.000067817964,0.000082111575,0.0000014314754],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.029929582,0.003288829,0.70105284,0.015125989,0.0006399057,0.0037528754,0.007053071,0.00041225564,0.038283605,0.0077309357,0.017877001,0.17485309],"study_design_scores_gemma":[0.03335284,0.0033999367,0.8621038,0.0035543186,0.007388184,0.00005703083,0.0069080633,0.0010322391,0.043123107,0.0058610677,0.031638067,0.0015813177],"about_ca_topic_score_codex":0.0007094632,"about_ca_topic_score_gemma":0.00008319011,"teacher_disagreement_score":0.17327176,"about_ca_system_score_codex":0.000029012688,"about_ca_system_score_gemma":0.00043468864,"threshold_uncertainty_score":0.42485952},"labels":[],"label_agreement":null},{"id":"W4407798854","doi":"10.1038/s41419-025-07436-z","title":"Inactivation of necroptosis-promoting protein MLKL creates a therapeutic vulnerability in colorectal cancer cells","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Government of Canada; Canadian Institutes of Health Research; Cancer Research Society; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Necroptosis; Colorectal cancer; Cancer research; Cancer; Vulnerability (computing); Programmed cell death; Cell biology; Biology; Apoptosis; Medicine; Internal medicine; Biochemistry; Computer science","score_opus":0.0067536013936897125,"score_gpt":0.24742439644640898,"score_spread":0.24067079505271927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407798854","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99660534,0.0019540528,0.0006068321,0.000056579494,0.000041169606,0.00039795495,0.000012597217,0.0000055182827,0.0003199436],"genre_scores_gemma":[0.9992932,0.00015985843,0.000104583625,0.000049936752,0.000021753396,0.00007802217,0.000035647277,0.0000067605088,0.00025025208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993672,0.000051542847,0.00015524843,0.00024653305,0.0000548905,0.00012458123],"domain_scores_gemma":[0.99969655,0.000009613751,0.00005628637,0.00011081075,0.00004601955,0.000080708414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008417066,0.000100506666,0.00010748123,0.000046895922,0.000050643685,0.000013004276,0.00004704383,0.00007357115,0.000011384213],"category_scores_gemma":[0.00002996565,0.00008861548,0.00004219085,0.00009026561,0.000035542256,0.0000048946886,0.000039653678,0.000043798656,2.2334739e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026024136,0.00014206173,0.016837275,0.00018291977,0.000008905812,7.0668096e-7,0.000039070474,0.000084379084,0.97770834,0.00021654942,0.000006498649,0.0045130355],"study_design_scores_gemma":[0.00051634695,0.000072363975,0.08310643,0.00004922972,0.000024277282,7.02324e-8,0.000028808905,0.0013208782,0.9133953,0.0012772307,0.00012131352,0.00008774501],"about_ca_topic_score_codex":0.000115953255,"about_ca_topic_score_gemma":0.000019014027,"teacher_disagreement_score":0.06626915,"about_ca_system_score_codex":0.000017291419,"about_ca_system_score_gemma":0.00012150792,"threshold_uncertainty_score":0.36136344},"labels":[],"label_agreement":null},{"id":"W4408987622","doi":"10.1038/s41419-025-07547-7","title":"A novel clinically relevant antagonistic interplay between prolactin and oncogenic YAP-CCN2 pathways as a differentiation therapeutic target in breast cancer","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"CIHR Skin Research Training Centre; Government of Canada","keywords":"Hippo signaling pathway; Biology; Cancer research; CD44; Breast cancer; Cancer; Cancer stem cell; Cancer cell; Cell biology; Cellular differentiation; Stem cell marker; Stem cell; Signal transduction; Cell; Genetics","score_opus":0.012137442956159155,"score_gpt":0.2879411941007853,"score_spread":0.27580375114462613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408987622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99359167,0.0030010848,0.0023076322,0.00027186723,0.00008187222,0.00025238987,0.00029682074,0.000014660242,0.00018197838],"genre_scores_gemma":[0.9981084,0.00055953197,0.0001053186,0.00061470486,0.00010013019,0.000054384866,0.00018496069,0.000015866146,0.00025673225],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99888146,0.000067233515,0.00028404163,0.00044845574,0.000081426726,0.00023736423],"domain_scores_gemma":[0.99936354,0.000044846714,0.000077331766,0.00019561498,0.000042683005,0.00027597134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015195273,0.00018449494,0.00019685729,0.00006116489,0.00008656075,0.000048848637,0.00009181147,0.00012386407,0.000013157325],"category_scores_gemma":[0.000071356786,0.0001612811,0.00006801063,0.000069442736,0.00005669386,0.0000053708172,0.00008218534,0.00012835913,0.0000026858577],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013255173,0.0002870149,0.4027728,0.00017868585,0.00006050495,0.000011925302,0.00009429756,0.000014338018,0.5899335,0.00008602204,0.000024151392,0.005211228],"study_design_scores_gemma":[0.0057277586,0.00052806083,0.94862,0.0003806534,0.0005089005,0.000011977468,0.00013364483,0.0034768502,0.03389211,0.0038575097,0.0020456938,0.0008168393],"about_ca_topic_score_codex":0.000053879787,"about_ca_topic_score_gemma":0.00000941245,"teacher_disagreement_score":0.5560414,"about_ca_system_score_codex":0.00001836853,"about_ca_system_score_gemma":0.00035338965,"threshold_uncertainty_score":0.6576852},"labels":[],"label_agreement":null},{"id":"W4409348345","doi":"10.1038/s41419-025-07598-w","title":"CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"CDC25A; Cdc25; Melanoma; Cancer research; Biology; Cell cycle; DNA damage; Cancer; Cell growth; Cell cycle checkpoint; Cyclin-dependent kinase 1; Genetics; DNA","score_opus":0.0060690238655424665,"score_gpt":0.2285194131116497,"score_spread":0.22245038924610722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409348345","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825392,0.011973343,0.001076187,0.00016902444,0.00007755357,0.00021614846,0.000030394252,0.000008991981,0.003909191],"genre_scores_gemma":[0.99407595,0.0031148223,0.00033963972,0.0009441706,0.00007286685,0.000011846365,0.00008232055,0.000010271807,0.0013480925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999329,0.000039141516,0.00011306928,0.0003113099,0.00005677783,0.00015070426],"domain_scores_gemma":[0.9994508,0.00001318601,0.000026097488,0.00018041892,0.000040522107,0.00028894382],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007231831,0.0001270834,0.00009212589,0.000050643048,0.00008780543,0.000042795054,0.00003070256,0.000070896145,0.000007420363],"category_scores_gemma":[0.00001541739,0.000118595766,0.000036276495,0.00005311484,0.000026337935,0.0000027714286,0.000058245827,0.000033548236,0.0000046356167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017603958,0.000058600097,0.004680831,0.000052180647,0.0000071823224,0.00000660625,0.000031430314,0.00002101821,0.99122953,0.00005858202,0.0007178343,0.0029601846],"study_design_scores_gemma":[0.0007429864,0.00014032183,0.010464017,0.000013073763,0.00002403351,1.9458156e-7,0.000035476645,0.00006577235,0.97712994,0.0007901316,0.010442067,0.00015200124],"about_ca_topic_score_codex":0.000014091005,"about_ca_topic_score_gemma":0.0000034678403,"teacher_disagreement_score":0.014099587,"about_ca_system_score_codex":0.000004494062,"about_ca_system_score_gemma":0.000053487467,"threshold_uncertainty_score":0.4836195},"labels":[],"label_agreement":null},{"id":"W4409376542","doi":"10.1038/s41419-025-07624-x","title":"Interleukin-33 (IL-33) promotes DNA damage-resistance in lung cancer","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Education and Child Care","funders":"National Natural Science Foundation of China; National Key Research and Development Program of China; Natural Science Foundation of Jilin Province","keywords":"DNA damage; DNA repair; Biology; Tumor microenvironment; Cancer research; Cancer; Cytokine; Immunology; DNA; Genetics; Tumor cells","score_opus":0.0065621858803494755,"score_gpt":0.23451863047269794,"score_spread":0.22795644459234846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409376542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95665646,0.020024179,0.00007075064,0.00022671616,0.0006266768,0.00036474952,0.0030172106,0.00006758723,0.018945653],"genre_scores_gemma":[0.97878104,0.00056103827,0.000026755191,0.00057998986,0.000034241075,0.00008348652,0.00015710508,0.000013243461,0.01976307],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.99879813,0.00010081679,0.00023451769,0.0004202112,0.00002854259,0.00041776683],"domain_scores_gemma":[0.999432,0.000066200904,0.000055599565,0.0002916776,0.000046563786,0.00010795295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009029362,0.00021949317,0.00025318773,0.00013148031,0.00017298672,0.000031499578,0.00018337913,0.00013758683,0.00013973366],"category_scores_gemma":[0.000102296115,0.00019827641,0.00006943655,0.00017010787,0.00013929278,0.00010133127,0.000104850296,0.00021356295,0.00004919893],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004783994,0.0021394137,0.5716255,0.0052980897,0.00042941852,0.00061411184,0.0046186806,0.00001971552,0.2519258,0.024499882,0.12827167,0.005773736],"study_design_scores_gemma":[0.008907479,0.0001481717,0.40725657,0.0012727104,0.0005326344,0.0000033913493,0.0005427419,0.00018314591,0.0692149,0.008309195,0.5023511,0.0012779377],"about_ca_topic_score_codex":0.00014853178,"about_ca_topic_score_gemma":0.00036176972,"teacher_disagreement_score":0.37407944,"about_ca_system_score_codex":0.00005774902,"about_ca_system_score_gemma":0.00035869158,"threshold_uncertainty_score":0.80854774},"labels":[],"label_agreement":null},{"id":"W4409380819","doi":"10.1038/s41419-025-07579-z","title":"Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer’s disease mouse model","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McMaster University; McGill University","funders":"National Institute on Aging; Lady Davis Institute for Medical Research; Fonds de Recherche du Québec - Santé; Canada First Research Excellence Fund; University of Oxford; Canadian Institutes of Health Research; Alzheimer Society; Scottish Rite Charitable Foundation of Canada; McGill University; Natural Sciences and Engineering Research Council of Canada; Pfizer","keywords":"Regulator; Disease; Alzheimer's disease; Cell biology; Biology; Neuroscience; Medicine; Genetics; Gene; Internal medicine","score_opus":0.030268996488671655,"score_gpt":0.3052562968643175,"score_spread":0.27498730037564584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409380819","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96816814,0.028734906,0.000010750392,0.00053931103,0.000029772753,0.0009632449,0.00026468057,0.00003820007,0.0012509796],"genre_scores_gemma":[0.9978891,0.00025647663,0.000058859514,0.00033312303,0.000027147162,0.00010932048,0.00008554884,0.000021984331,0.0012184582],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985013,0.000097181444,0.00025293647,0.00042455265,0.00035798174,0.000366046],"domain_scores_gemma":[0.99729806,0.00004045024,0.00005380138,0.00084950624,0.00009087362,0.0016673359],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009093079,0.00021933,0.00027006344,0.00013717465,0.000112335445,0.000027778453,0.00019582636,0.000052326595,0.00004282739],"category_scores_gemma":[0.00010069147,0.00015135964,0.00016381359,0.00019912045,0.00021408539,0.00017004051,0.00017239021,0.00012539397,0.000005288894],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004886273,0.003406405,0.9860049,0.00071385765,0.0007541361,0.00025754154,0.00009751159,0.00046925643,0.00014991878,0.0010806595,0.0010868971,0.0010926505],"study_design_scores_gemma":[0.0053130174,0.00008654025,0.9508284,0.00022363075,0.0022455978,6.4588187e-7,0.00008516743,0.033115707,0.0019618673,0.0058653234,0.000041575877,0.0002325255],"about_ca_topic_score_codex":0.00005681238,"about_ca_topic_score_gemma":0.000008742062,"teacher_disagreement_score":0.03517649,"about_ca_system_score_codex":0.000034739824,"about_ca_system_score_gemma":0.0011165043,"threshold_uncertainty_score":0.6172267},"labels":[],"label_agreement":null},{"id":"W4409493903","doi":"10.1038/s41419-025-07623-y","title":"Loss of VHL-mediated pRb regulation promotes clear cell renal cell carcinoma","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Institute of Infection and Immunity; University of Waterloo; Ottawa Hospital; McGill University; University of Ottawa","funders":"Government of Canada; Natural Sciences and Engineering Research Council of Canada; Ottawa Hospital Research Institute; Canadian Institutes of Health Research; Cancer Research Society; University of Ottawa","keywords":"Transactivation; Ubiquitin ligase; Clear cell renal cell carcinoma; Cancer research; Proteasome; Carcinogenesis; Retinoblastoma protein; Hypoxia-inducible factors; Ubiquitin; Gene silencing; Biology; Transcription factor; Tumor suppressor gene; Cell growth; Cullin; Cell cycle; Cell biology; Cell; Cancer; Renal cell carcinoma; Gene; Medicine; Genetics; Internal medicine","score_opus":0.005003546280644928,"score_gpt":0.20891993310299736,"score_spread":0.20391638682235244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409493903","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98106205,0.01351141,0.00018962365,0.000047371148,0.00022779276,0.00023400645,0.00009394634,0.000009823534,0.0046239686],"genre_scores_gemma":[0.99368954,0.0005151224,0.000113400194,0.00015535152,0.0002698318,0.00001461452,0.00029620575,0.000012916729,0.004933048],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991894,0.00003776932,0.00017629274,0.00031520711,0.00009048749,0.00019086886],"domain_scores_gemma":[0.99930066,0.000009753457,0.00007505777,0.00028124216,0.00007704243,0.00025626828],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006336663,0.00014009769,0.00014175447,0.000050749197,0.000059863218,0.00001586741,0.000089949965,0.0000963918,0.000023740422],"category_scores_gemma":[0.000037542202,0.00013351589,0.00008554764,0.00008177205,0.000066856504,0.000004703697,0.00006980113,0.00005143753,0.0000039717834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008443925,0.00032790564,0.024597168,0.0005437628,0.000013630527,0.0000048923266,0.000060736827,0.000024797859,0.96487606,0.000076826014,0.0076194457,0.0010103659],"study_design_scores_gemma":[0.0027467443,0.00028747102,0.10905584,0.00002776375,0.00022345608,9.709493e-7,0.00004685803,0.00028175898,0.815429,0.00041603277,0.07116636,0.00031777422],"about_ca_topic_score_codex":0.000027216705,"about_ca_topic_score_gemma":0.0000036593128,"teacher_disagreement_score":0.1494471,"about_ca_system_score_codex":0.0000062225836,"about_ca_system_score_gemma":0.00024659748,"threshold_uncertainty_score":0.544462},"labels":[],"label_agreement":null},{"id":"W4411077462","doi":"10.1038/s41419-025-07755-1","title":"Muscle stem cells in Duchenne muscular dystrophy exhibit molecular impairments and altered cell fate trajectories impacting regenerative capacity","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Defeat Duchenne Canada; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Government of Canada; Muscular Dystrophy Canada; Stem Cell Network; McGill University","keywords":"Duchenne muscular dystrophy; Biology; Stem cell; Progenitor cell; Dystrophin; Cell biology; Myogenesis; mdx mouse; Regeneration (biology); Satellite; Cellular differentiation; Muscular dystrophy; Cell fate determination; Myocyte; Genetics; Gene; Transcription factor","score_opus":0.007203958155822287,"score_gpt":0.21804851844229936,"score_spread":0.21084456028647708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411077462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99460125,0.0038760803,0.00034344385,0.00003430086,0.0001066742,0.00035061096,0.00006714541,0.000012112066,0.00060838595],"genre_scores_gemma":[0.9989603,0.0002473224,0.00013426733,0.00030846766,0.00003900716,0.00005399958,0.0000598808,0.000015060947,0.00018165303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873114,0.00012850999,0.00019648987,0.00053991395,0.00006867114,0.00033529292],"domain_scores_gemma":[0.99928695,0.000015324504,0.00006298409,0.00027998467,0.00003944516,0.0003153214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000091252434,0.00024581596,0.00020345165,0.00006730661,0.00011827895,0.00003810141,0.00009063673,0.000120649616,0.000005372053],"category_scores_gemma":[0.000022107335,0.00023828236,0.00008512052,0.000091219175,0.00010742503,0.00001269267,0.000106192376,0.00011108409,0.000001246345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037238217,0.00020729995,0.0086622005,0.00023143594,0.000028948134,0.000029276416,0.00014438413,0.0002474311,0.98932064,0.000066906076,0.000121882105,0.00056722434],"study_design_scores_gemma":[0.004348175,0.00038521943,0.054701645,0.000060480823,0.00014046466,0.0000014727148,0.0007399807,0.00045414656,0.936543,0.0011967951,0.0007959036,0.0006327545],"about_ca_topic_score_codex":0.00008638608,"about_ca_topic_score_gemma":0.000011778493,"teacher_disagreement_score":0.052777667,"about_ca_system_score_codex":0.000015409214,"about_ca_system_score_gemma":0.0001223866,"threshold_uncertainty_score":0.97168726},"labels":[],"label_agreement":null},{"id":"W4411844393","doi":"10.1038/s41419-025-07789-5","title":"Inhibition of Wnt/β-catenin increases anti-tumor activity by synergizing with sorafenib in hepatocellular carcinoma","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Liver physiology and pathology","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Natural Science Foundation of Tianjin City; Polytechnique Montréal; National Natural Science Foundation of China; Tianjin Medical University; Université de Montréal","keywords":"Sorafenib; Wnt signaling pathway; Hepatocellular carcinoma; Cancer research; Medicine; Tyrosine-kinase inhibitor; MAPK/ERK pathway; Catenin; Apoptosis; Pharmacology; In vivo; Protein kinase B; Drug resistance; Cancer; Internal medicine; Oncology; Kinase; Chemistry; Signal transduction; Biology","score_opus":0.008954572977811626,"score_gpt":0.22120014283741998,"score_spread":0.21224556985960835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411844393","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99735266,0.0016144528,0.00006246745,0.00007754528,0.00002078731,0.00022854234,0.000036651298,0.000016578388,0.0005902902],"genre_scores_gemma":[0.9993911,0.000047869948,0.000029048691,0.00028164132,0.000015933421,0.00001953334,0.000080827806,0.000006825704,0.00012725542],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99934196,0.000076776036,0.00011977579,0.00024368994,0.00005809783,0.00015970551],"domain_scores_gemma":[0.9995519,0.000054139487,0.000050955445,0.00012341709,0.000033204236,0.00018637853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000063717016,0.00011844072,0.00026314412,0.00010454806,0.00004462074,0.0000036631302,0.00002680514,0.000052401512,0.000013926762],"category_scores_gemma":[0.000036777317,0.00009612812,0.000036535464,0.00012639633,0.00011972714,0.00006040578,0.000033607535,0.00010656906,0.00000199203],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013723394,0.0005048972,0.82398516,0.00040968016,0.000009915781,0.0004998673,0.00003688854,0.0000021967637,0.17284599,0.00014995995,0.00011705386,0.000066051536],"study_design_scores_gemma":[0.002817143,0.00021006256,0.85086966,0.00017226707,0.00020625179,0.000008811563,0.00005655102,0.00045558088,0.14454192,0.0005269348,0.000015227135,0.00011958459],"about_ca_topic_score_codex":0.00029320017,"about_ca_topic_score_gemma":0.0000033213826,"teacher_disagreement_score":0.028304078,"about_ca_system_score_codex":0.000015020889,"about_ca_system_score_gemma":0.00019076437,"threshold_uncertainty_score":0.3919991},"labels":[],"label_agreement":null},{"id":"W4411844429","doi":"10.1038/s41419-025-07778-8","title":"p66Shc deletion confers apoptotic resistance to loss of EGFR-ERK signalling in neural stem cells","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; London Health Sciences Centre; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Neural stem cell; MAPK/ERK pathway; Apoptosis; Epidermal growth factor; Cell biology; Biology; Epidermal growth factor receptor; Cancer research; Signal transduction; Signal transducing adaptor protein; Stem cell; Receptor; Genetics","score_opus":0.010312848425152038,"score_gpt":0.23538445144957537,"score_spread":0.22507160302442333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411844429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99051166,0.004307214,0.0022354473,0.00035182567,0.000119489334,0.00048564465,0.000022788108,0.000023873345,0.0019420617],"genre_scores_gemma":[0.99790365,0.00009886397,0.00014928562,0.00067272864,0.000019206187,0.000017898099,0.000012934374,0.000012532885,0.0011129192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910873,0.00003524416,0.0002337098,0.00027517663,0.00014385098,0.00020328637],"domain_scores_gemma":[0.99926287,0.000037328115,0.000044151762,0.00020192185,0.00006387071,0.00038983783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007768603,0.00012305491,0.00021538693,0.00015475768,0.000029826675,0.000011932542,0.0000530054,0.000053478096,0.000014377755],"category_scores_gemma":[0.000032322667,0.00012557252,0.00006431011,0.00023062131,0.000036929043,0.000026476993,0.000028551935,0.00011026447,0.000005816209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014985024,0.0013260483,0.06602454,0.008822279,0.00013661811,0.0021456925,0.0010955023,0.0130156465,0.87571967,0.0038259078,0.004988349,0.007914722],"study_design_scores_gemma":[0.023335852,0.0008923025,0.080952115,0.006266331,0.0018216243,0.000007981825,0.0009858069,0.022483544,0.8515535,0.0017598445,0.008499359,0.0014417501],"about_ca_topic_score_codex":0.000022618575,"about_ca_topic_score_gemma":0.000013819008,"teacher_disagreement_score":0.024166176,"about_ca_system_score_codex":0.00008232847,"about_ca_system_score_gemma":0.00024128325,"threshold_uncertainty_score":0.5120699},"labels":[],"label_agreement":null},{"id":"W4411947520","doi":"10.1038/s41419-025-07819-2","title":"Transglutaminase 2 function in glioblastoma tumor efferocytosis","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Blood properties and coagulation","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; St. Michael's Hospital; Ottawa Hospital","funders":"Government of Canada; Ottawa Hospital Research Institute; Canadian Institutes of Health Research; University of Ottawa","keywords":"Efferocytosis; Biology; Apoptosis; Cancer research; Phagocytosis; Cell biology; Pathology; Macrophage; Medicine; In vitro","score_opus":0.007511498728980375,"score_gpt":0.2177972582225614,"score_spread":0.21028575949358103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411947520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939539,0.0030671833,0.00024251551,0.0004193854,0.00006126391,0.00022274168,0.0000035915634,0.000029931949,0.001999492],"genre_scores_gemma":[0.99741566,0.000042885258,0.000018998195,0.0012655952,0.00002838732,0.000028682014,0.000007728066,0.000005669933,0.0011863847],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9995397,0.000015605981,0.000105396204,0.00016094281,0.0000638991,0.000114466784],"domain_scores_gemma":[0.99964076,0.0000121123985,0.0000114816585,0.00011210674,0.000017494369,0.00020602673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000034168872,0.000079006866,0.000110963585,0.00009136284,0.000041671035,0.000012959153,0.000017367653,0.000025192337,0.000043334207],"category_scores_gemma":[0.000020476318,0.000065070664,0.00003892095,0.000118850956,0.000015722735,0.000041698448,0.000010053761,0.000055207423,0.000008417789],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02133934,0.0013619498,0.8666081,0.0028157695,0.000050354458,0.00036129783,0.00022913823,0.00005409295,0.011334909,0.001382559,0.0015403792,0.092922136],"study_design_scores_gemma":[0.00445448,0.00040516417,0.9817516,0.00023642601,0.00043098288,0.0000027273932,0.00010785894,0.0032501651,0.005449807,0.0009020396,0.0028720882,0.00013666532],"about_ca_topic_score_codex":0.000022996634,"about_ca_topic_score_gemma":0.000006261165,"teacher_disagreement_score":0.11514352,"about_ca_system_score_codex":0.000016526332,"about_ca_system_score_gemma":0.00007210029,"threshold_uncertainty_score":0.26535046},"labels":[],"label_agreement":null},{"id":"W4411980242","doi":"10.1038/s41419-025-07808-5","title":"The trapping of live neutrophils by macrophages during infection","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Dental and Craniofacial Research; U.S. Department of Health and Human Services","keywords":"Cell biology; Phagosome; Internalization; Biology; Innate immune system; Phagocytosis; Efferocytosis; Inflammation; Microbiology; Azurophilic granule; Neutrophil extracellular traps; Degranulation; Elastase; Immune system; Macrophage; Receptor; Immunology; In vitro; Myeloperoxidase","score_opus":0.004501201682372874,"score_gpt":0.21143037055359726,"score_spread":0.2069291688712244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411980242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9581639,0.040714327,0.000057251862,0.00012716734,0.00015167762,0.000104903,0.000011714975,0.000015149961,0.00065390626],"genre_scores_gemma":[0.9954539,0.0020005566,0.0000011133501,0.000033840588,0.0000065279232,0.000010375654,0.000023051816,0.000003064214,0.0024675543],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995858,0.000052731964,0.00012319938,0.000108989596,0.0000114687045,0.00011782074],"domain_scores_gemma":[0.99974954,0.0000454763,0.00004815409,0.000112667076,0.000021491842,0.000022640024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000044827193,0.00006828787,0.00008483839,0.000031910222,0.00027237902,0.000013541793,0.000042145006,0.00004311566,0.000019924817],"category_scores_gemma":[0.000024720111,0.000049513787,0.000047330093,0.00005014289,0.00007641211,0.00004453224,0.000029971281,0.00005547657,0.000007411455],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002791688,0.00009502206,0.023082031,0.00011421334,0.000054689524,8.5727993e-7,0.000072574345,0.000009059518,0.96921986,0.0006649457,0.0016118219,0.0047957324],"study_design_scores_gemma":[0.0012368264,0.00004187923,0.64983714,0.00005231924,0.00010379395,0.0000012508905,0.00005344424,0.000025658399,0.34119913,0.0006867977,0.0066649406,0.000096802214],"about_ca_topic_score_codex":0.000035789104,"about_ca_topic_score_gemma":7.868453e-7,"teacher_disagreement_score":0.62802076,"about_ca_system_score_codex":0.000009390507,"about_ca_system_score_gemma":0.000027990578,"threshold_uncertainty_score":0.20949468},"labels":[],"label_agreement":null},{"id":"W4412165430","doi":"10.1038/s41419-025-07815-6","title":"Rb substantially compensates for the double loss of p130 and p107 in adult but not embryonic neural stem cell lineages","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Faculty of Arts and Sciences; Centre National de la Recherche Scientifique; American University of Beirut","keywords":"Embryonic stem cell; Neural stem cell; Cell biology; Stem cell; Biology; Genetics; Gene","score_opus":0.014175443151756213,"score_gpt":0.2620029888031665,"score_spread":0.24782754565141032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412165430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898929,0.008658261,0.00014950844,0.00034795576,0.000057684912,0.00047747663,0.00010784087,0.000004411455,0.00030397956],"genre_scores_gemma":[0.9949507,0.0017731041,0.000035722995,0.00019202879,0.00003336657,0.00003471722,0.00005534666,0.000010406369,0.002914598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991608,0.000038412116,0.00016697019,0.0002978831,0.000093693154,0.00024221954],"domain_scores_gemma":[0.99937594,0.00008109503,0.000044654415,0.00024766853,0.0000914789,0.00015918458],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012329822,0.00012946661,0.00014316375,0.00004479261,0.00008075203,0.00003599964,0.00016474634,0.000064846696,0.0000025429263],"category_scores_gemma":[0.000020167847,0.000097674856,0.00006379593,0.00006321997,0.0001157246,0.0000043595155,0.00013935399,0.000066994195,7.883899e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0061116084,0.00041425086,0.113137,0.0022797151,0.00006435288,0.00004898028,0.00008005743,0.00041197997,0.87404525,0.00058183697,0.00097056275,0.00185442],"study_design_scores_gemma":[0.007620493,0.00028187025,0.05553154,0.000070260256,0.00014162018,0.0000022263916,0.0003178482,0.011062852,0.9221018,0.00011036839,0.00242543,0.00033367335],"about_ca_topic_score_codex":0.000042511856,"about_ca_topic_score_gemma":0.000034583998,"teacher_disagreement_score":0.057605464,"about_ca_system_score_codex":0.000005068252,"about_ca_system_score_gemma":0.00012912929,"threshold_uncertainty_score":0.3983065},"labels":[],"label_agreement":null},{"id":"W4412366526","doi":"10.1038/s41419-025-07854-z","title":"SUMOylation of the lysine-less tumor suppressor p14ARF counters ubiquitylation-dependent degradation","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Instituto de Investigación Sanitaria de Santiago de Compostela; Ministerio de Ciencia, Innovación y Universidades; Fundación Banco Santander","keywords":"SUMO protein; Neddylation; p14arf; Lysine; Cell biology; Ubiquitin; Biology; Chemistry; Molecular biology; Biochemistry; Ubiquitin ligase; Carcinogenesis; Tumor suppressor gene; Amino acid; Gene","score_opus":0.009889732438506552,"score_gpt":0.23082220003481846,"score_spread":0.2209324675963119,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412366526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947924,0.0011397903,0.001067118,0.00016611243,0.00011552156,0.00025621883,0.00008444632,0.000006466593,0.0023719475],"genre_scores_gemma":[0.99821806,0.000043747215,0.000048191036,0.00031797166,0.00003914626,0.000022247434,0.00013842399,0.0000060506923,0.0011661379],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994192,0.000050559272,0.00013813481,0.0001897633,0.00009847718,0.00010387317],"domain_scores_gemma":[0.9995222,0.000012143136,0.00007114027,0.00023803819,0.00006656024,0.00008990608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000084047206,0.0000905228,0.000073850366,0.000027861912,0.000091853784,0.0000223817,0.000104251594,0.00003933811,0.000010927078],"category_scores_gemma":[0.00007876969,0.00007113466,0.00005589146,0.00005868921,0.000045024462,0.0000054076154,0.000078911624,0.00003688245,0.0000011265648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054491486,0.0002128513,0.20168544,0.00044858505,0.000040969135,0.0000029357655,0.000093642106,0.00021935884,0.7914485,0.0022257187,0.0015384984,0.0015386383],"study_design_scores_gemma":[0.000997377,0.000046028465,0.11489003,0.000054538767,0.00011362852,8.5612874e-7,0.00009353203,0.0008480408,0.87850314,0.0012330154,0.003049626,0.00017019447],"about_ca_topic_score_codex":0.00001690242,"about_ca_topic_score_gemma":0.000008797015,"teacher_disagreement_score":0.087054685,"about_ca_system_score_codex":0.000008130663,"about_ca_system_score_gemma":0.00013338104,"threshold_uncertainty_score":0.2900787},"labels":[],"label_agreement":null},{"id":"W4412793596","doi":"10.1038/s41419-026-08686-1","title":"The RIPK3-IL-6 axis mediates kidney injury in cytokine storm syndrome","year":2025,"lang":"en","type":"preprint","venue":"Cell Death and Disease","topic":"Acute Kidney Injury Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"Instituto de Salud Carlos III","keywords":"Necroptosis; Inflammasome; Cytokine storm; Kidney; Acute kidney injury; Bone marrow; Cancer research; Biology; Medicine; Inflammation; Cytokine; Cell biology; Immunology; Pathology; Programmed cell death; Internal medicine; Apoptosis","score_opus":0.016410638265875473,"score_gpt":0.3002673540117949,"score_spread":0.2838567157459194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412793596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91928583,0.012902243,0.00003714038,0.023062376,0.0015526477,0.003906593,0.017118922,0.0002486698,0.02188557],"genre_scores_gemma":[0.9691223,0.007983157,0.00013435776,0.0034105089,0.0002954162,0.0006510919,0.0018698518,0.000053922227,0.0164794],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.99727654,0.00014538749,0.00048318345,0.00079477864,0.0006179579,0.000682123],"domain_scores_gemma":[0.9953067,0.00022242217,0.00011044971,0.0011774285,0.00014798585,0.0030350375],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005140769,0.00045129887,0.0006126567,0.00036922042,0.0001921659,0.000113233575,0.00045582702,0.00031220692,0.00020019482],"category_scores_gemma":[0.00223237,0.00032074473,0.00020856725,0.0002669474,0.00024537317,0.00005871419,0.0012240197,0.0012652728,0.00006719786],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006030067,0.001222401,0.4530701,0.007846474,0.00034473604,0.0039817705,0.00043143358,0.0000024233182,0.00033231455,0.0005147465,0.51885015,0.0073733777],"study_design_scores_gemma":[0.0089802705,0.0009452344,0.50335115,0.0033967446,0.001792018,0.000060966137,0.00025689078,0.0023493145,0.0010418437,0.0152132055,0.46085778,0.0017545946],"about_ca_topic_score_codex":0.00023561604,"about_ca_topic_score_gemma":0.000007901251,"teacher_disagreement_score":0.05799238,"about_ca_system_score_codex":0.00023175801,"about_ca_system_score_gemma":0.0037758923,"threshold_uncertainty_score":0.9999245},"labels":[],"label_agreement":null},{"id":"W4413843359","doi":"10.1038/s41419-025-07980-8","title":"Targeting DDX3X suppresses progression of KRAS-driven lung cancer by disrupting antioxidative homeostasis and inducing ferroptosis","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Sun Yat-sen University Cancer Center; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College; Canadian Institutes of Health Research; Peking Union Medical College; Nanfang Hospital; Peking Union Medical College Hospital; Southern Medical University; China Academy of Chinese Medical Sciences; OeAD-GmbH; National Natural Science Foundation of China; Sun Yat-sen University; CIHR Skin Research Training Centre; Bundesministerium für Bildung, Wissenschaft und Forschung; Cancer Research Institute; Österreichischen Akademie der Wissenschaften; Government of Canada","keywords":"KRAS; Homeostasis; Cancer research; Lung cancer; Biology; Cancer; Cell biology; Medicine; Internal medicine; Colorectal cancer; Genetics","score_opus":0.006792340760677853,"score_gpt":0.2929295038768288,"score_spread":0.28613716311615095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413843359","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9446531,0.05365546,0.0009988982,0.00011942064,0.000034356315,0.00016497573,0.00015915606,0.0000058022265,0.00020882276],"genre_scores_gemma":[0.9918453,0.0073893513,0.00029964442,0.00006978023,0.000028763103,0.000056664998,0.00013638042,0.000008320234,0.00016580115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936306,0.000030451663,0.00013374719,0.00027815628,0.000058520713,0.0001360434],"domain_scores_gemma":[0.999588,0.000013730356,0.00007599187,0.00013057119,0.000061453764,0.00013021697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045546247,0.00010438606,0.00010417653,0.00003213098,0.00013324231,0.00002905579,0.00005766064,0.000049616778,0.000011277459],"category_scores_gemma":[0.000064436485,0.00009182593,0.00002873628,0.00006949677,0.0000591389,0.0000086107575,0.00008886221,0.000040750885,8.134805e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119193486,0.000091508155,0.25852183,0.0004286768,0.000045904668,0.0000011345683,0.00010937163,0.00007870107,0.72351694,0.00004423899,0.0029226665,0.014119832],"study_design_scores_gemma":[0.0019729303,0.0001354162,0.09038395,0.00061180344,0.00045146252,5.768194e-7,0.0009951837,0.0049012527,0.8911196,0.000103256774,0.008703224,0.0006213471],"about_ca_topic_score_codex":0.000039998788,"about_ca_topic_score_gemma":0.0000015029169,"teacher_disagreement_score":0.16813788,"about_ca_system_score_codex":0.000008036677,"about_ca_system_score_gemma":0.000090308655,"threshold_uncertainty_score":0.3744553},"labels":[],"label_agreement":null},{"id":"W4414845098","doi":"10.1038/s41419-025-07999-x","title":"IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pancreas Centre (Canada)","funders":"Zhejiang University; National Natural Science Foundation of China; Natural Science Foundation of Shanghai","keywords":"Sting; Pancreatic cancer; Downregulation and upregulation; Signal transduction; Chemotherapy; Proteostasis; Unfolded protein response; Apoptosis; Transmembrane protein","score_opus":0.007657731004420635,"score_gpt":0.2455209953551076,"score_spread":0.23786326435068697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414845098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9504931,0.045996718,0.00025861638,0.0004417288,0.00023660001,0.00014964926,0.000053045012,0.00002450968,0.0023460242],"genre_scores_gemma":[0.9833448,0.00048192244,0.000020453588,0.00026093377,0.0000067253177,0.000034359153,0.00006246188,0.000005350732,0.015783023],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99933743,0.00007971573,0.00015800039,0.00020948096,0.000022494205,0.0001928556],"domain_scores_gemma":[0.9997213,0.00007811566,0.000028614173,0.000110652065,0.000021975182,0.00003933952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059229515,0.00011072451,0.00013873981,0.00008475014,0.00009821886,0.0000149399675,0.000074892996,0.000066017805,0.00045169963],"category_scores_gemma":[0.00004010043,0.00009454207,0.000041992724,0.000055703644,0.00004658078,0.00004725485,0.000028403887,0.00010206823,0.000021255546],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008191799,0.00065342785,0.47374535,0.0005889719,0.00010872686,0.000059204136,0.00043479868,0.00015280882,0.50040185,0.002403584,0.006305462,0.006954025],"study_design_scores_gemma":[0.0036966237,0.00003691606,0.87137115,0.0004159505,0.00014090708,0.000002755721,0.00015467172,0.0003628677,0.11713778,0.0013905898,0.005029727,0.00026008135],"about_ca_topic_score_codex":0.000112338676,"about_ca_topic_score_gemma":0.000020506086,"teacher_disagreement_score":0.39762577,"about_ca_system_score_codex":0.00001752572,"about_ca_system_score_gemma":0.00013663307,"threshold_uncertainty_score":0.4945794},"labels":[],"label_agreement":null},{"id":"W4414885939","doi":"10.1038/s41419-025-08016-x","title":"SARS-CoV-2 delta and omicron variants alter trophoblast cell fusion and syncytiotrophoblast dynamics: new insights into placental vulnerability","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"COVID-19 Impact on Reproduction","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Université de Genève","keywords":"Cytotrophoblast; Trophoblast; Syncytiotrophoblast; Cell fusion; Placenta; Permissiveness; Viral replication; Receptor; Syncytium","score_opus":0.010297196708910003,"score_gpt":0.2740512918188853,"score_spread":0.26375409510997533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414885939","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923133,0.0038588035,0.0011955946,0.0012455968,0.00021198527,0.0006520568,0.000030087207,0.000060417256,0.00043210745],"genre_scores_gemma":[0.99662036,0.00068373024,0.00034801738,0.0013710674,0.00012237906,0.000009572732,0.00007845749,0.000023092221,0.00074332335],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99841684,0.000070277194,0.00028140374,0.0007938238,0.0001593589,0.00027829394],"domain_scores_gemma":[0.99865687,0.000066079214,0.0000712443,0.00046137066,0.000055913653,0.000688507],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000099089135,0.000290111,0.00032359437,0.00019053127,0.00021215655,0.0000855144,0.000055042507,0.00010501673,0.000020838512],"category_scores_gemma":[0.00018007375,0.00025495765,0.00006035361,0.00015977399,0.0001320756,0.00016861566,0.00017063349,0.00019776572,0.000007901231],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0074827145,0.0012423397,0.16473296,0.003182721,0.000059537564,0.00020784217,0.0009911499,0.000015379255,0.7996571,0.00020242896,0.004729413,0.017496431],"study_design_scores_gemma":[0.023419162,0.0012401196,0.7957858,0.0007078199,0.0015000781,0.000069244255,0.00050581025,0.03479044,0.12611839,0.009034458,0.0056858924,0.0011428021],"about_ca_topic_score_codex":0.000733146,"about_ca_topic_score_gemma":0.000093152594,"teacher_disagreement_score":0.6735387,"about_ca_system_score_codex":0.00024906304,"about_ca_system_score_gemma":0.00046217215,"threshold_uncertainty_score":0.9999903},"labels":[],"label_agreement":null},{"id":"W4415262471","doi":"10.1038/s41419-025-07959-5","title":"Pharmacological activation of SIRT6 suppresses progression of head and neck and esophageal squamous cell carcinoma by modulation of cellular metabolism and protein translation","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"Israel Science Foundation; National Natural Science Foundation of China; European Commission","keywords":"SIRT6; Head and neck squamous-cell carcinoma; PI3K/AKT/mTOR pathway; Sirtuin; Acetylation; Cell growth; Activator (genetics); Histone; Ribosomal protein s6","score_opus":0.012498336589219663,"score_gpt":0.276562378764,"score_spread":0.26406404217478036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415262471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96978575,0.028699204,0.0003792436,0.00016905833,0.000020399913,0.00075695966,0.00002909812,0.000007657122,0.00015262075],"genre_scores_gemma":[0.9991111,0.0002935676,0.0003503411,0.00003818746,0.000028152286,0.000017465354,0.00006676725,0.0000065587988,0.000087869055],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992255,0.000052183812,0.00025562185,0.00021031169,0.00015639394,0.00009999383],"domain_scores_gemma":[0.99947745,0.000058136004,0.000107512984,0.00008236772,0.000071510214,0.00020300975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009117827,0.00012206328,0.00028996196,0.00009205382,0.00004416728,0.000005746483,0.00002007232,0.0000790828,0.000011738284],"category_scores_gemma":[0.000038551385,0.00008856284,0.00002816929,0.00008570406,0.00013798769,0.0000699974,0.00002040297,0.000074265496,2.0147564e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00180731,0.00043121906,0.07277508,0.0023627186,0.0000131756415,0.000008437965,0.00020712145,0.000007777224,0.9158897,0.000058831538,0.00006959774,0.0063690227],"study_design_scores_gemma":[0.0073798806,0.00056483253,0.35078162,0.00017147984,0.0005434325,0.0000010526823,0.000087077526,0.008299722,0.6317611,0.00023662444,0.000085844746,0.000087351305],"about_ca_topic_score_codex":0.000031145824,"about_ca_topic_score_gemma":1.6300261e-7,"teacher_disagreement_score":0.28412864,"about_ca_system_score_codex":0.0000043024625,"about_ca_system_score_gemma":0.000052303618,"threshold_uncertainty_score":0.36114877},"labels":[],"label_agreement":null},{"id":"W4415523238","doi":"10.1038/s41419-025-08098-7","title":"A microRNA CRISPR screen reveals microRNA-483-3p as an apoptotic regulator in prostate cancer cells","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"microRNA; CRISPR; Prostate cancer; Regulator; Cell; Cancer; Cell growth; Apoptosis; RNA interference","score_opus":0.006096965372326085,"score_gpt":0.2575901148018243,"score_spread":0.25149314942949824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415523238","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897222,0.008366691,0.00006892237,0.00024805355,0.00011085163,0.0006398564,0.00021253913,0.000020921383,0.0006099579],"genre_scores_gemma":[0.99427396,0.00061022985,0.000277116,0.0011604691,0.00010137615,0.00008024039,0.00032383658,0.000032299566,0.0031404626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984122,0.00010249863,0.0003024429,0.00068217306,0.000109128334,0.00039157472],"domain_scores_gemma":[0.99870205,0.000009742594,0.000095234725,0.00052909344,0.0000873398,0.0005765123],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012853787,0.00026902047,0.00020856534,0.000118384305,0.000099587494,0.00007335183,0.00018914022,0.000121642704,0.000057791596],"category_scores_gemma":[0.00005107103,0.0002743547,0.000094377196,0.00015513042,0.00008706662,0.00001531588,0.00012801115,0.0000869991,0.000013368278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007164795,0.00021708706,0.02702448,0.00027076053,0.000026884003,0.000029685869,0.00004022312,0.00007265963,0.96694744,0.00009139884,0.0038348655,0.0007280207],"study_design_scores_gemma":[0.002718429,0.00012575957,0.17154302,0.00020219688,0.00021355625,0.0000032458274,0.00008011206,0.00026267744,0.81063014,0.0020165017,0.011546497,0.0006578647],"about_ca_topic_score_codex":0.00017120027,"about_ca_topic_score_gemma":0.000037884714,"teacher_disagreement_score":0.15631731,"about_ca_system_score_codex":0.000047222125,"about_ca_system_score_gemma":0.0004416407,"threshold_uncertainty_score":0.99997085},"labels":[],"label_agreement":null},{"id":"W4415591451","doi":"10.1038/s41419-025-08103-z","title":"Impairment of lysosomal quality control in Huntington disease","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; AFM-Téléthon; Università degli Studi di Trento; Ministero dell’Istruzione, dell’Università e della Ricerca; U.S. Department of Health and Human Services; Fondazione Cariplo; Fondazione Telethon; Università degli Studi di Milano; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Kennedy's Disease Association","keywords":"TFEB; Lysosome; Huntingtin; TFE3; Proteotoxicity; Transcription factor; Gene knockdown; Gene silencing","score_opus":0.01729512797157004,"score_gpt":0.27997836599059406,"score_spread":0.26268323801902405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415591451","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970815,0.00045917524,0.00017339803,0.00034920918,0.00010853687,0.0004454944,0.00019475506,0.000026216598,0.0011616733],"genre_scores_gemma":[0.9974043,0.000049215403,0.000017116818,0.00207918,0.000016485235,0.00005458284,0.0000053686026,0.000008551545,0.0003652326],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984479,0.0002777891,0.0003098743,0.0004940603,0.00020558032,0.00026480036],"domain_scores_gemma":[0.9987327,0.00022674652,0.00007956092,0.0003300813,0.00003254734,0.000598396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000099647405,0.00016480821,0.00020327185,0.00012173946,0.00007425963,0.000032518314,0.00015110205,0.000019968353,0.000036383357],"category_scores_gemma":[0.0009614109,0.00015502803,0.000095306714,0.00018988008,0.000117683696,0.00006462177,0.000082915045,0.000059627066,0.0000056743106],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010956073,0.0011107987,0.8477278,0.00041732434,0.0000028366583,0.000028525372,0.000038364633,0.00025553736,0.14302947,0.005754309,0.0001675726,0.00037188167],"study_design_scores_gemma":[0.0021285582,0.00003721708,0.86310977,0.000041350166,0.000059280348,3.4963698e-8,0.000021230388,0.00068918336,0.12989469,0.003776703,0.00008812146,0.00015389262],"about_ca_topic_score_codex":0.000022009785,"about_ca_topic_score_gemma":0.00000236636,"teacher_disagreement_score":0.015381977,"about_ca_system_score_codex":0.0000188071,"about_ca_system_score_gemma":0.00029220775,"threshold_uncertainty_score":0.63218594},"labels":[],"label_agreement":null},{"id":"W4416088035","doi":"10.1038/s41419-025-08150-6","title":"A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Windsor Clinical Research; University of Windsor; McGill University Health Centre; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Alliance de recherche numérique du Canada; Research Councils UK; U.S. Department of Health and Human Services; Government of Canada; Wellcome Trust; National Institute of Diabetes and Digestive and Kidney Diseases; McGill University","keywords":"Regulator; In silico; Drug discovery; Drug repositioning; Programmed cell death; Repurposing; Cell; Cancer cell; Colorectal cancer","score_opus":0.009789698537625343,"score_gpt":0.28905909958927745,"score_spread":0.2792694010516521,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416088035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87967056,0.0007781356,0.117280066,0.0002560829,0.0002084774,0.0009431686,0.00020105588,0.000015532634,0.0006469402],"genre_scores_gemma":[0.988814,0.00004282105,0.008442856,0.00069184543,0.00015428581,0.00032293415,0.000091128495,0.00002749515,0.0014126435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875355,0.000029171391,0.00024233286,0.0005465062,0.00015305696,0.00027536054],"domain_scores_gemma":[0.9991539,0.000010025234,0.00007718658,0.00030995364,0.00010365643,0.00034529227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007479374,0.00020457794,0.00018720026,0.000093430855,0.00013603098,0.000074043164,0.0001709491,0.00008735214,0.000013320576],"category_scores_gemma":[0.00009306453,0.00020039575,0.00011623991,0.00016835333,0.000057104582,0.0000142838435,0.00023980736,0.00008770958,0.0000020142604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001083254,0.00042146575,0.0036296584,0.00018328536,0.0001177698,0.0000022082058,0.0002123592,0.0012357492,0.9899881,0.00021304596,0.00074554194,0.00216757],"study_design_scores_gemma":[0.0019990136,0.00023228707,0.03404723,0.00024368668,0.00031794203,0.0000030601586,0.00036162583,0.0006557537,0.95274633,0.00018570671,0.008621594,0.0005857719],"about_ca_topic_score_codex":0.00033951394,"about_ca_topic_score_gemma":0.000011823478,"teacher_disagreement_score":0.10914344,"about_ca_system_score_codex":0.000032495773,"about_ca_system_score_gemma":0.00019734225,"threshold_uncertainty_score":0.8171902},"labels":[],"label_agreement":null},{"id":"W4416724337","doi":"10.1038/s41419-025-08268-7","title":"Inhibition of MCL-1 to eliminate senescent cells and mitigate renal fibrosis in aristolochic acid nephropathy","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Nephrotoxicity and Medicinal Plants","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Senescence; Aristolochic acid; Downregulation and upregulation; Apoptosis; DNA damage; Acute kidney injury; Kidney disease; Kidney; Nephropathy","score_opus":0.007321661071314929,"score_gpt":0.2335893653551714,"score_spread":0.22626770428385648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416724337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99641967,0.0013949857,0.00012675897,0.0006895929,0.000053033556,0.0004454884,0.00006198831,0.0000131173,0.00079534005],"genre_scores_gemma":[0.9966998,0.0003541042,0.00022582445,0.0022772609,0.000024854717,0.000019152658,0.000027080845,0.000006052419,0.00036585022],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991993,0.000032371943,0.00020928727,0.00024300182,0.00012598763,0.0001901024],"domain_scores_gemma":[0.9991983,0.000029727496,0.000036444955,0.0001337147,0.00003428243,0.0005675036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010351383,0.00012473694,0.00024400794,0.00020135446,0.000039614086,0.000008697855,0.000023290339,0.000052338066,0.00000996534],"category_scores_gemma":[0.00006749919,0.00011060319,0.00003659705,0.0001575463,0.000058301903,0.000038927672,0.000042153933,0.00010114611,0.0000043682303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029884728,0.00038898597,0.018299498,0.0019719831,0.000013115678,0.00039098863,0.00039826188,0.0000053468566,0.9699362,0.000103753606,0.0011043926,0.0043989867],"study_design_scores_gemma":[0.0039655645,0.00043401757,0.20377803,0.001975653,0.00031805522,0.000009925431,0.00036064137,0.00021787557,0.7870057,0.0006856494,0.0010580341,0.00019083591],"about_ca_topic_score_codex":0.00004803779,"about_ca_topic_score_gemma":0.000007835236,"teacher_disagreement_score":0.18547852,"about_ca_system_score_codex":0.000024520901,"about_ca_system_score_gemma":0.00013359894,"threshold_uncertainty_score":0.45102674},"labels":[],"label_agreement":null},{"id":"W4417137531","doi":"10.1038/s41419-025-08309-1","title":"Noncanonical role of astrocytic mitochondrial Cx43: suppressing IDH3α to sustain glycolytic homeostasis against depression","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Servier; National Natural Science Foundation of China","keywords":"Glycolysis; Oxidative phosphorylation; Anaerobic glycolysis; Mitochondrion; Reprogramming; Warburg effect; Homeostasis; Connexin; Intracellular","score_opus":0.003967084503794459,"score_gpt":0.23532741248302086,"score_spread":0.2313603279792264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417137531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912613,0.0054580593,0.0008950301,0.0001114414,0.000116696436,0.00025073157,0.00006388399,0.000008864216,0.0018340055],"genre_scores_gemma":[0.9982479,0.00012527822,0.00035787848,0.0005640139,0.00012259363,0.000024792265,0.00010353432,0.000010750612,0.00044324104],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900955,0.000058460144,0.00019690851,0.00039414564,0.00006922136,0.0002717376],"domain_scores_gemma":[0.99917156,0.000027405998,0.000045160858,0.00032115873,0.000060496364,0.00037420754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000048816382,0.00015309715,0.00018065092,0.000073980045,0.00008576184,0.000024619436,0.00013738939,0.00011421231,0.000013603318],"category_scores_gemma":[0.00017819584,0.00013842947,0.000094724586,0.00008067807,0.00006290465,0.0000033685242,0.00022001035,0.00006323389,0.0000022349618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022441824,0.00019001083,0.02026668,0.00013584759,0.000035290068,0.000019436475,0.000031433778,0.00010456934,0.9525899,0.00014322647,0.002063722,0.022175662],"study_design_scores_gemma":[0.0071402183,0.0008989907,0.05813853,0.00026450123,0.00040475262,0.0000051014445,0.0006759201,0.0014471845,0.7573218,0.0008480312,0.17189273,0.0009622422],"about_ca_topic_score_codex":0.000012327343,"about_ca_topic_score_gemma":0.0000074540135,"teacher_disagreement_score":0.19526815,"about_ca_system_score_codex":0.0000152219345,"about_ca_system_score_gemma":0.00033827938,"threshold_uncertainty_score":0.564499},"labels":[],"label_agreement":null},{"id":"W595869321","doi":"10.1038/cddis.2015.119","title":"The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institutes of Health; National Institute of Environmental Health Sciences; Multiple Sclerosis Society; National Institute of Neurological Disorders and Stroke; Shriners Hospitals for Children","keywords":"Remyelination; Biology; Conditional gene knockout; Cell biology; p38 mitogen-activated protein kinases; Oligodendrocyte; Protein kinase A; Myelin; Cellular differentiation; Progenitor cell; Kinase; Neuroscience; Central nervous system; Stem cell; Biochemistry; Phenotype; Gene","score_opus":0.03911362993179598,"score_gpt":0.2492915117480156,"score_spread":0.2101778818162196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W595869321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99809515,0.00026627549,0.000058085076,0.0008597686,0.0000773958,0.0004637069,0.000020780495,0.000013657468,0.00014518031],"genre_scores_gemma":[0.9991829,0.00008456291,0.000016180204,0.0004898359,0.000025616719,0.00003572975,0.0000015876416,0.000009979631,0.00015361387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891263,0.00023106979,0.00016450076,0.000266991,0.0002766829,0.00014809369],"domain_scores_gemma":[0.9992834,0.00016858194,0.00008887638,0.00020321879,0.00005217068,0.0002037841],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021742529,0.00010590759,0.00008274872,0.00005068071,0.00015394855,0.00006535245,0.00012314705,0.00002730035,0.000002724242],"category_scores_gemma":[0.00087449996,0.00006524896,0.000025593383,0.00017955806,0.00007448396,0.00010181758,0.000049011607,0.00006691922,0.000002657078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003760197,0.0001418145,0.00042461918,0.000043574855,8.195365e-7,0.00003319775,0.0005746368,0.0000060725706,0.9911779,0.0058073774,0.00016397226,0.0012499859],"study_design_scores_gemma":[0.00075535284,0.00012751989,0.005333155,0.000017500855,0.000017133778,0.0000035612477,0.000109326385,0.0021670333,0.98744714,0.002949748,0.0009792577,0.0000932404],"about_ca_topic_score_codex":0.00000850173,"about_ca_topic_score_gemma":0.000001680186,"teacher_disagreement_score":0.0049085356,"about_ca_system_score_codex":0.00000913723,"about_ca_system_score_gemma":0.00007084567,"threshold_uncertainty_score":0.26607752},"labels":[],"label_agreement":null},{"id":"W7116708222","doi":"10.1038/s41419-025-08206-7","title":"Capicua regulates the survival of Cajal-Retzius cells in the postnatal hippocampus","year":2025,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Université de Paris; Canada Foundation for Innovation; University of Alberta; Scottish Rite Charitable Foundation of Canada; Government of Canada; Canada Research Chairs; Women and Children's Health Research Institute","keywords":"Programmed cell death; Hippocampal formation; Apoptosis; Embryonic stem cell; Cell; Hippocampus; Cell growth; Cell fate determination; Transcriptome","score_opus":0.0160757343063616,"score_gpt":0.2322186980578513,"score_spread":0.2161429637514897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7116708222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975001,0.0004281647,0.000017764758,0.00035534965,0.00032698526,0.00026261737,0.00005745976,0.000014385343,0.0010371738],"genre_scores_gemma":[0.99781513,0.00017636752,0.0000033599013,0.0016351047,0.000020640893,0.000011934589,0.0000013825463,0.000008039959,0.00032806513],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988314,0.00025801055,0.00017603309,0.00030963926,0.00020674197,0.00021818608],"domain_scores_gemma":[0.99885964,0.00061611866,0.000051764073,0.00033890616,0.000015879898,0.00011766348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014466353,0.00013453342,0.00012763466,0.00005856276,0.00015455447,0.000050753184,0.00032667993,0.000026293375,0.000013224563],"category_scores_gemma":[0.00023921907,0.00007772255,0.0000633473,0.00023112533,0.00012128281,0.00004536533,0.00009845728,0.00010595863,0.0000067497017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027227882,0.00031183343,0.0029113898,0.00013674125,0.0000025345441,0.0004610355,0.00023378109,0.00007339356,0.9774886,0.01722093,0.00048760977,0.0003999246],"study_design_scores_gemma":[0.00049694383,0.000059156282,0.019901333,0.000019282268,0.000046379446,0.0000071171726,0.00010445435,0.000526619,0.9754299,0.0028817637,0.000416496,0.00011057291],"about_ca_topic_score_codex":0.000020691496,"about_ca_topic_score_gemma":0.0000041489266,"teacher_disagreement_score":0.016989945,"about_ca_system_score_codex":0.00000501119,"about_ca_system_score_gemma":0.00007886108,"threshold_uncertainty_score":0.31694335},"labels":[],"label_agreement":null}]}