{"meta":{"query_hash":"39b5d41ae50a","filters":{"venue":"Current Topics in Medicinal Chemistry"},"cohort_total":80,"direct_labels_cover":0,"predictions_cover":80,"exported":80,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/39b5d41ae50a","api":"https://metacan.xera.ac/api/v1/cohort?venue=Current+Topics+in+Medicinal+Chemistry"},"results":[{"id":"W1166129206","doi":"10.2174/1568026615666150819110018","title":"Interplay between Catalysts and Substrates for Activity of Class Ib Aminoacyl-tRNA Synthetases and Implications for Pharmacology","year":2015,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Aminoacyl tRNA synthetase; Transfer RNA; Chemistry; Pharmacology; Biochemistry; Computational biology; Biology; RNA; Gene","score_opus":0.08311332264072763,"score_gpt":0.4272377403120706,"score_spread":0.344124417671343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1166129206","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00026610796,0.99815446,0.00022271737,0.00016966503,0.00012505209,0.0000027681115,0.000015507654,0.000007750962,0.0010359635],"genre_scores_gemma":[0.0018133203,0.99679726,0.00029452945,0.00013499286,0.000121859164,0.000005540077,0.00003317595,0.0000016857492,0.0007976609],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.999889,0.000017264201,0.000017036204,0.000022538376,0.000037353708,0.000016823651],"domain_scores_gemma":[0.99985635,0.000059203823,0.000027615879,0.0000056499603,0.000033647022,0.0000174665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034772966,0.00058211555,0.00093783136,0.0012882935,0.00019412891,0.0007818495,0.0006129167,0.0007865521,0.002096654],"category_scores_gemma":[0.0004046261,0.00025105773,0.00029405078,0.0012759482,0.00045987454,0.0011007814,0.0006033901,0.0012575208,0.0015967899],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010710349,0.00005640401,0.00021057582,0.013134164,0.00005351073,0.00024283191,0.00006721511,0.00056695094,0.007202579,0.008588376,0.011910874,0.9578593],"study_design_scores_gemma":[0.000012483722,0.000108372005,0.0008071385,0.0015625033,0.00006881183,0.0013707014,0.00006685482,0.0001411359,0.0020763953,0.0035427108,0.9902227,0.000020155921],"about_ca_topic_score_codex":0.00042578817,"about_ca_topic_score_gemma":0.0007546512,"teacher_disagreement_score":0.002096654,"about_ca_system_score_codex":0.00053370965,"about_ca_system_score_gemma":0.0006592853,"threshold_uncertainty_score":0.0070139766},"labels":[],"label_agreement":null},{"id":"W190250652","doi":"10.2174/1568026054367601","title":"Proteases and Protease-Activated Receptors (PARs): Novel Signals for Pain","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Proteases; Neuroscience; Nociception; Protease; Receptor; Protease-activated receptor; Central nervous system; Biology; Enzyme; Biochemistry; Immunology; Thrombin","score_opus":0.13325307947113177,"score_gpt":0.39322862000510267,"score_spread":0.2599755405339709,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W190250652","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00035424985,0.9978689,0.0003132532,0.00031051412,0.00016893893,0.0000033840718,0.0000068503705,0.000008554369,0.00096543366],"genre_scores_gemma":[0.0019451678,0.99596065,0.00037939404,0.00019596153,0.00033178425,0.000005482857,0.000014873721,0.00000114327,0.0011655311],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998431,0.000028842527,0.000019431478,0.000024633599,0.000065346496,0.000018644918],"domain_scores_gemma":[0.9998568,0.000054534954,0.00002759333,0.000004534105,0.000035732577,0.000020627303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045534107,0.00073670654,0.0009302629,0.0013226281,0.00024496298,0.00097466627,0.00048149822,0.0012366859,0.0025475817],"category_scores_gemma":[0.00031287194,0.00020602116,0.00025636132,0.0013160675,0.0005362084,0.0015541665,0.00040528201,0.0011746583,0.0027025382],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017240425,0.00010361914,0.00030312678,0.006415401,0.000059165926,0.0007438951,0.000111648085,0.0002640527,0.014840803,0.0056174863,0.015556034,0.9558124],"study_design_scores_gemma":[0.00006237313,0.0003257464,0.0018470136,0.0011344582,0.00008253882,0.0053069135,0.00018956746,0.00015611667,0.005919873,0.0050445492,0.9798982,0.000032541153],"about_ca_topic_score_codex":0.00028414006,"about_ca_topic_score_gemma":0.0004794462,"teacher_disagreement_score":0.0025475817,"about_ca_system_score_codex":0.00037089328,"about_ca_system_score_gemma":0.00043199337,"threshold_uncertainty_score":0.00852257},"labels":[],"label_agreement":null},{"id":"W1966039777","doi":"10.2174/156802607780487795","title":"Nucleobase Modifications in Peptide Nucleic Acids","year":2007,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nucleic acid; Nucleobase; Peptide nucleic acid; Oligonucleotide; DNA; Nucleic acid analogue; Chemistry; RNA; Combinatorial chemistry; Polyamide; Peptide; Glycine; Nucleic acid methods; Biochemistry; Amino acid; Nucleic acid thermodynamics; Organic chemistry; Gene","score_opus":0.056427028630866065,"score_gpt":0.3709538644284818,"score_spread":0.31452683579761576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966039777","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004266998,0.9847088,0.0024979063,0.00015184039,0.00034369837,0.0000263054,0.000032912965,0.00005154967,0.007919985],"genre_scores_gemma":[0.019528024,0.96898055,0.003502871,0.00025483067,0.00020221282,0.00004248927,0.000083446765,0.000009509633,0.0073961196],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998772,0.000018097482,0.000009850247,0.000029983812,0.00005192649,0.000012829513],"domain_scores_gemma":[0.99995804,0.000014723085,0.000009273316,0.0000028875718,0.000009735764,0.00000529233],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021082556,0.00071004016,0.00059766223,0.0007333251,0.00017794677,0.00034326597,0.0004528372,0.0006251882,0.0013264846],"category_scores_gemma":[0.00017164584,0.00027058748,0.00017071237,0.0008884155,0.0002991468,0.0005037769,0.00035891106,0.00068740913,0.0022426557],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008554042,0.00011631734,0.00015116337,0.00933491,0.000050057624,0.00079734495,0.0001433172,0.0009765288,0.21895269,0.008638482,0.0072802994,0.7534734],"study_design_scores_gemma":[0.000021631138,0.00026001997,0.0006367682,0.0006233586,0.00004037014,0.0034725305,0.0000348384,0.00022632568,0.09190238,0.0017617584,0.90099424,0.000025763888],"about_ca_topic_score_codex":0.00033184886,"about_ca_topic_score_gemma":0.00050060183,"teacher_disagreement_score":0.0013264846,"about_ca_system_score_codex":0.00033852246,"about_ca_system_score_gemma":0.00023957492,"threshold_uncertainty_score":0.004437506},"labels":[],"label_agreement":null},{"id":"W1970801600","doi":"10.2174/1568026043387728","title":"Preface [Hot Topic: Pharmacogenomics (Guest Editor: Amadeo M. Parissenti)]","year":2004,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Northeast Cancer Centre","funders":"","keywords":"Pharmacogenomics; Medicine; Pharmacology","score_opus":0.09419277259503857,"score_gpt":0.4482717134690607,"score_spread":0.35407894087402214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970801600","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010562216,0.009511786,0.00044509664,0.053581476,0.93389475,0.00003846434,0.00016664785,0.00007954013,0.0021766683],"genre_scores_gemma":[0.0011340556,0.009964814,0.00050147035,0.040496297,0.9311671,0.00004447285,0.0002118048,0.00008032046,0.016399695],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998708,0.00028909015,0.00027721547,0.00020440079,0.00045314795,0.00006826572],"domain_scores_gemma":[0.97841346,0.0063000848,0.0010539478,0.00047162198,0.011215809,0.0025450299],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030370855,0.0018410935,0.002728529,0.0032411935,0.0013871276,0.0030838137,0.0023318501,0.004629672,0.029968675],"category_scores_gemma":[0.018605474,0.00053507346,0.0013764395,0.0018162896,0.00086780527,0.0028241635,0.00096408685,0.008231253,0.028170116],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028832063,0.0000085491,0.000057270106,0.00018166672,0.00000859442,0.00016893345,0.000008933895,0.00002647081,0.00007130929,0.00011247847,0.9886164,0.01071047],"study_design_scores_gemma":[0.000040128867,0.000055257817,0.0013155628,0.00042795713,0.000036593716,0.0011769698,0.00004504067,0.0002702894,0.00021566001,0.0010935671,0.9952918,0.0000311706],"about_ca_topic_score_codex":0.0017507268,"about_ca_topic_score_gemma":0.0024438228,"teacher_disagreement_score":0.029968675,"about_ca_system_score_codex":0.0009621511,"about_ca_system_score_gemma":0.0011066466,"threshold_uncertainty_score":0.10025519},"labels":[],"label_agreement":null},{"id":"W1972833860","doi":"10.2174/1568026615666150225104543","title":"Anesthetics Act in Quantum Channels in Brain Microtubules to Prevent Consciousness","year":2015,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Anesthetic; Chemistry; Microtubule; Biophysics; Tubulin; Cell biology; Biology; Medicine; Anesthesia","score_opus":0.08915941179643098,"score_gpt":0.3810980718300935,"score_spread":0.2919386600336625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972833860","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94472575,0.014571656,0.0266601,0.0019789054,0.00027185804,0.00006401087,0.00013019693,0.00040039065,0.011197175],"genre_scores_gemma":[0.9821468,0.008651987,0.0053569255,0.00044567348,0.00006449864,0.000031669253,0.000057262157,0.000024542473,0.0032206895],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.999915,0.000013315588,0.000005000193,0.000017167486,0.000025594607,0.000023921659],"domain_scores_gemma":[0.9998925,0.000026087928,0.000048153805,0.000008893831,0.000012427417,0.000011989596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014990785,0.00022845746,0.00017905101,0.00018189441,0.000501994,0.0004116163,0.00032957,0.0005825684,0.0020784184],"category_scores_gemma":[0.00026076508,0.00014597751,0.00031315605,0.00012381854,0.00061532494,0.0010985882,0.00038996,0.0006282245,0.00044979498],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020457168,0.000074215495,0.0008752151,0.0002934196,0.000026573214,0.00032977786,0.00014526669,0.001380691,0.95767426,0.023315087,0.00068834535,0.014992533],"study_design_scores_gemma":[0.00006418512,0.0007419714,0.003512342,0.000042217776,0.000055083896,0.00057274447,0.0001850342,0.005188091,0.9665462,0.0062975376,0.01677069,0.000023971697],"about_ca_topic_score_codex":0.0007224731,"about_ca_topic_score_gemma":0.00078127853,"teacher_disagreement_score":0.0020784184,"about_ca_system_score_codex":0.0004051012,"about_ca_system_score_gemma":0.00033587695,"threshold_uncertainty_score":0.006953001},"labels":[],"label_agreement":null},{"id":"W1979788892","doi":"10.2174/156802605774643006","title":"Editorial [Hot Topic: C-Glycosides and Related Sugar Derivatives in Medicinal Chemistry (Guest Editor: Wei Zou)]","year":2005,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Glycoside; Chemistry; Sugar; Traditional medicine; Organic chemistry; Medicine","score_opus":0.012346932052465155,"score_gpt":0.26570197820112096,"score_spread":0.2533550461486558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979788892","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000100257355,0.0076795714,0.00012987795,0.018103529,0.9726716,0.000025329067,0.000049608134,0.00005329317,0.0011868813],"genre_scores_gemma":[0.0007339651,0.0045007076,0.00010813505,0.01764132,0.97180915,0.000020127161,0.000035554665,0.000027219068,0.0051237945],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99789846,0.00035542954,0.00030232937,0.00033542886,0.00090269215,0.00020575196],"domain_scores_gemma":[0.9931034,0.0019971346,0.0009343529,0.00020962532,0.0021765088,0.0015790027],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0034284452,0.003959935,0.0044018347,0.003692348,0.0025156527,0.004485616,0.0033834102,0.012496889,0.012881786],"category_scores_gemma":[0.009727626,0.0012076786,0.0028644728,0.0016382984,0.001470205,0.0024501395,0.0013518938,0.010234758,0.008754429],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107852415,0.000018608152,0.000047700334,0.00039719927,0.000046918773,0.00032610225,0.000007885299,0.000031873606,0.0002344675,0.00014646583,0.9894426,0.009192332],"study_design_scores_gemma":[0.00016031595,0.00011524484,0.0008000672,0.00036131756,0.0002074785,0.00079127046,0.000026851287,0.00025408462,0.00041707067,0.0004764691,0.9963611,0.000028756336],"about_ca_topic_score_codex":0.0008029232,"about_ca_topic_score_gemma":0.0022062054,"teacher_disagreement_score":0.012881786,"about_ca_system_score_codex":0.0015956439,"about_ca_system_score_gemma":0.0012888471,"threshold_uncertainty_score":0.04309386},"labels":[],"label_agreement":null},{"id":"W1981440072","doi":"10.2174/156802606778249810","title":"Serotonin Reuptake Inhibitors: The Corner Stone in Treatment of Depression for Half a Century – A Medicinal Chemistry Survey","year":2006,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Treatment of Major Depression","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Freie Universität Berlin; H. Lundbeck A/S; Merck KGaA; McGill University; Sanofi","keywords":"Reuptake inhibitor; Antidepressant; Reuptake; Medicine; Population; Depression (economics); Psychiatry; Broad spectrum; Pharmacology; Serotonin; Psychology; Chemistry; Internal medicine","score_opus":0.08870736064322807,"score_gpt":0.3946901556649448,"score_spread":0.30598279502171677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981440072","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029957682,0.99675566,0.00019400178,0.00049099774,0.00022839819,0.0000095312425,0.000019081735,0.000013631082,0.001989108],"genre_scores_gemma":[0.00084214,0.9969438,0.00034466624,0.0003164276,0.00027028602,0.00000561148,0.00002912293,0.0000012963432,0.001246727],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998485,0.0000243788,0.000018656721,0.000024335783,0.000070862276,0.000013196921],"domain_scores_gemma":[0.9998456,0.00005271514,0.000027204742,0.0000045520774,0.000046951995,0.000022924336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004553697,0.0006117072,0.0010534022,0.001571689,0.0002409117,0.0006233645,0.0005947701,0.000749143,0.0046308017],"category_scores_gemma":[0.00031313964,0.0002025481,0.00027042013,0.0021674465,0.00024346418,0.0013002773,0.000326358,0.001055015,0.0032348558],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000090604844,0.00013795788,0.00015662432,0.0069529135,0.000046857655,0.00018860743,0.000050109138,0.00025135174,0.002876928,0.0017918285,0.032354362,0.9551017],"study_design_scores_gemma":[0.000051906136,0.0003093886,0.0018213368,0.0024544622,0.00008137536,0.0018330284,0.00009302873,0.00015375452,0.0007210616,0.001751793,0.9907128,0.00001596986],"about_ca_topic_score_codex":0.00069658575,"about_ca_topic_score_gemma":0.0020722155,"teacher_disagreement_score":0.0046308017,"about_ca_system_score_codex":0.0003916966,"about_ca_system_score_gemma":0.000601446,"threshold_uncertainty_score":0.015491605},"labels":[],"label_agreement":null},{"id":"W1982873906","doi":"10.2174/1568026013395605","title":"Multidrug Efflux in Pseudomonas aeruginosa Components, Mechanisms and Clinical Significance","year":2001,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":269,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Cystic Fibrosis Canada; Ministry of Education, Culture, Sports, Science and Technology; Cystic Fibrosis Foundation","keywords":"Efflux; Pseudomonas aeruginosa; Multiple drug resistance; Biology; Periplasmic space; Microbiology; Bacterial outer membrane; Antimicrobial; Antiporter; Antibiotic resistance; Quorum sensing; Homoserine; Drug resistance; Bacteria; Biochemistry; Antibiotics; Genetics; Membrane; Escherichia coli; Gene; Virulence","score_opus":0.05694919784018947,"score_gpt":0.37855860811244946,"score_spread":0.32160941027226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982873906","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23982805,0.7190063,0.0038426507,0.019439999,0.00030670178,0.00012765959,0.00031540773,0.0001864688,0.016946722],"genre_scores_gemma":[0.8734746,0.11911899,0.0014025326,0.0011247623,0.00068691047,0.00008610223,0.00024178361,0.000014842033,0.003849467],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99982136,0.000045639936,0.000018867615,0.000023125265,0.000050455725,0.000040684965],"domain_scores_gemma":[0.99974567,0.000074891475,0.000057653553,0.000015677115,0.000058673384,0.000047469635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004397966,0.00026197045,0.00029823414,0.0004828097,0.00032897387,0.0011117507,0.00028601216,0.0007690474,0.0012761209],"category_scores_gemma":[0.00084152375,0.000116584575,0.0001372783,0.000570266,0.00071907305,0.0006674627,0.00040700412,0.00082017004,0.00039534934],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002016049,0.0006096278,0.07683135,0.004710309,0.00006885838,0.01605224,0.0008915303,0.00065513264,0.3119331,0.038401853,0.012429906,0.53540003],"study_design_scores_gemma":[0.0003155522,0.0036540783,0.3888456,0.0013104234,0.00024435058,0.11580181,0.0016062612,0.0026930473,0.066255674,0.031503383,0.38759843,0.00017135721],"about_ca_topic_score_codex":0.00076092075,"about_ca_topic_score_gemma":0.00039713547,"teacher_disagreement_score":0.0012761209,"about_ca_system_score_codex":0.00065511104,"about_ca_system_score_gemma":0.000656462,"threshold_uncertainty_score":0.004753232},"labels":[],"label_agreement":null},{"id":"W1986740601","doi":"10.2174/156802609789207109","title":"Steroid Hormone Binding Receptors: Application of Homology Modeling, Induced Fit Docking, and Molecular Dynamics to Study Structure- Function Relationships","year":2009,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McMaster University","keywords":"Docking (animal); Homology modeling; Computational biology; Receptor; Nuclear receptor; Transcription factor; Steroid hormone; Binding site; Homology (biology); Steroid; Gene; Chemistry; Biology; Ligand (biochemistry); Hormone; Biochemistry; Medicine; Enzyme","score_opus":0.035630737577273544,"score_gpt":0.33471936660083673,"score_spread":0.2990886290235632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986740601","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011409416,0.7430426,0.22861175,0.0009202498,0.00040594768,0.000096222335,0.00026454177,0.0011115979,0.01413772],"genre_scores_gemma":[0.08729074,0.7757511,0.12883864,0.00026730567,0.00024538612,0.00025323877,0.00067852606,0.00016709433,0.006507982],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99980253,0.00005005373,0.000009857555,0.00003748465,0.000087652385,0.000012462615],"domain_scores_gemma":[0.99986446,0.00006833318,0.000017338056,0.000012884231,0.000027708276,0.000009377939],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052556477,0.00097265973,0.0020648374,0.0007643692,0.00019775477,0.0007170188,0.0014419326,0.00083528407,0.0014176125],"category_scores_gemma":[0.00052723085,0.0003662364,0.00059489114,0.0017397228,0.00046587404,0.00085683906,0.00049528474,0.0009777206,0.0014613081],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015143612,0.0001707009,0.0006000786,0.0044409297,0.00034895222,0.00034682607,0.00010121008,0.13705204,0.01728711,0.03810462,0.010345692,0.7910505],"study_design_scores_gemma":[0.00023750494,0.00055648445,0.0017622327,0.0009698461,0.0002984957,0.001960453,0.0001650934,0.41935292,0.030939853,0.054952864,0.48859084,0.00021351107],"about_ca_topic_score_codex":0.0019126749,"about_ca_topic_score_gemma":0.0012836214,"teacher_disagreement_score":0.0020648374,"about_ca_system_score_codex":0.00063481875,"about_ca_system_score_gemma":0.00051626685,"threshold_uncertainty_score":0.004742384},"labels":[],"label_agreement":null},{"id":"W1992723722","doi":"10.2174/156802605774642999","title":"C-Glycosides and Aza-C-Glycosides as Potential Glycosidase and Glycosyltransferase Inhibitors","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":161,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"National Research Council Canada","keywords":"Glycoside hydrolase; Glycosyltransferase; Glycoside; Chemistry; Glycosylation; Anomer; Enzyme; Stereochemistry; Biochemistry","score_opus":0.028433474427392916,"score_gpt":0.3189391996700521,"score_spread":0.29050572524265916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992723722","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0042539365,0.98427063,0.0016212639,0.00023926681,0.0002923052,0.000027055488,0.00004671632,0.000036080433,0.009212619],"genre_scores_gemma":[0.019036734,0.9671788,0.0024110193,0.00030909394,0.00020743116,0.000033572265,0.00010918862,0.0000052175938,0.010708959],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99991834,0.000011376828,0.0000069846187,0.000013377123,0.000039137194,0.000010741759],"domain_scores_gemma":[0.9999678,0.0000069985335,0.000006339493,0.0000016258513,0.000010605725,0.0000066485486],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017874806,0.0006547528,0.0004990681,0.0008708697,0.00014618156,0.00037173714,0.00036118197,0.0005062198,0.0023394679],"category_scores_gemma":[0.000115714036,0.0001450494,0.00019188506,0.0008322614,0.00019402974,0.0005608508,0.00022603532,0.00068582856,0.0018265139],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002019031,0.00024893382,0.00023453153,0.0049126176,0.000056878605,0.0006893686,0.00007115863,0.0014674846,0.08410871,0.011491219,0.014017614,0.88249964],"study_design_scores_gemma":[0.000060846975,0.00041308347,0.0009551313,0.0004374271,0.000054411285,0.0020289996,0.000037689017,0.00049910176,0.03263511,0.001848495,0.9610069,0.000022893579],"about_ca_topic_score_codex":0.00042441,"about_ca_topic_score_gemma":0.00095646887,"teacher_disagreement_score":0.0023394679,"about_ca_system_score_codex":0.00035437808,"about_ca_system_score_gemma":0.00025965562,"threshold_uncertainty_score":0.007826328},"labels":[],"label_agreement":null},{"id":"W1995536355","doi":"10.2174/1568026043387610","title":"The Use of DNA Microarrays to Investigate the Pharmacogenomics of Drug Response in Living Systems","year":2004,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Northeast Cancer Centre","funders":"","keywords":"Pharmacogenomics; Drug response; DNA microarray; Drug; Computational biology; Pharmacology; Medicine; Biology; Genetics; Gene; Gene expression","score_opus":0.08537657184318984,"score_gpt":0.35824097702110747,"score_spread":0.27286440517791766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995536355","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0037731193,0.9176087,0.06362461,0.0018475112,0.00083780393,0.00014798869,0.0002679688,0.0003591178,0.011533183],"genre_scores_gemma":[0.01383615,0.91471183,0.06300109,0.0013849502,0.00053180486,0.00024758553,0.00035939203,0.000030606003,0.005896579],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99911636,0.00021219964,0.000047330846,0.00016336954,0.00041637028,0.000044386234],"domain_scores_gemma":[0.99946326,0.0002734897,0.00005371882,0.00003881899,0.00014729776,0.000023442984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016227283,0.0009108637,0.0018883754,0.003025504,0.0003732846,0.0013000842,0.0011887522,0.0012903136,0.001264705],"category_scores_gemma":[0.0009262105,0.0004552391,0.0005644522,0.0034965568,0.0010865409,0.0016094829,0.0005146646,0.0015584314,0.0025558588],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012501475,0.0001184579,0.0006481274,0.006297921,0.000118168944,0.0002974859,0.00014027837,0.0014453417,0.19360952,0.014009181,0.010087842,0.77310264],"study_design_scores_gemma":[0.00004396167,0.0003549068,0.0034810822,0.0009830934,0.00014485473,0.002511618,0.0001830074,0.0020722402,0.14423016,0.014099882,0.8317738,0.0001213501],"about_ca_topic_score_codex":0.000936819,"about_ca_topic_score_gemma":0.0013192841,"teacher_disagreement_score":0.003025504,"about_ca_system_score_codex":0.0010066465,"about_ca_system_score_gemma":0.00057587796,"threshold_uncertainty_score":0.008581877},"labels":[],"label_agreement":null},{"id":"W2005358308","doi":"10.2174/156802609789630839","title":"Peptide Mediated siRNA Delivery","year":2009,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Peptide; Chemistry; Computational biology; Biology; Biochemistry","score_opus":0.04327762646527263,"score_gpt":0.3440909782378076,"score_spread":0.300813351772535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005358308","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.021605808,0.90119046,0.033624943,0.0006011962,0.00096224266,0.00027728293,0.00029452084,0.00041686793,0.04102657],"genre_scores_gemma":[0.11760204,0.8198123,0.024987068,0.0010138435,0.00030759335,0.0003445191,0.00048705505,0.0000488142,0.035396874],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999846,0.000022555274,0.00001453514,0.000041891057,0.000057561603,0.000017407901],"domain_scores_gemma":[0.99995875,0.000010548636,0.000010539435,0.0000025548502,0.000013202505,0.000004472063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021927935,0.0006669244,0.0006099572,0.0006640542,0.00017839849,0.00052140263,0.0005624761,0.00065160444,0.0014322966],"category_scores_gemma":[0.00015492711,0.0001653777,0.00022244967,0.0004474647,0.00025847324,0.0005023085,0.00042008498,0.00067565934,0.0020881263],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007930829,0.00009334682,0.0001693526,0.0056476234,0.00006686113,0.0009936646,0.00011459113,0.0006945668,0.5075925,0.008945485,0.0069644363,0.46863824],"study_design_scores_gemma":[0.00003405359,0.00041462053,0.0006318353,0.0003880545,0.0000739385,0.004478594,0.000038027116,0.00071919744,0.43878427,0.00121708,0.5531832,0.000037055812],"about_ca_topic_score_codex":0.00029189026,"about_ca_topic_score_gemma":0.00031505793,"teacher_disagreement_score":0.0014322966,"about_ca_system_score_codex":0.0004529838,"about_ca_system_score_gemma":0.00030661438,"threshold_uncertainty_score":0.004791498},"labels":[],"label_agreement":null},{"id":"W2006622195","doi":"10.2174/156802612799078973","title":"Multifunctional Ligands in Medicinal Inorganic Chemistry- Current Trends and Future Directions","year":2012,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Alzheimer Society","keywords":"Current (fluid); Chemistry; Nanotechnology; Engineering; Materials science","score_opus":0.09409219675027601,"score_gpt":0.35660647991914585,"score_spread":0.2625142831688698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006622195","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003663854,0.99403787,0.0016153115,0.00054665504,0.00027040567,0.000011814079,0.000011312619,0.000028985363,0.003111239],"genre_scores_gemma":[0.003337456,0.9903048,0.002506239,0.0005586671,0.0005304524,0.00002314454,0.000028674891,0.000009577938,0.0027009493],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997019,0.000058217618,0.00002816622,0.00006222308,0.00010957399,0.000039971386],"domain_scores_gemma":[0.9996062,0.00020536223,0.000055644516,0.000015815522,0.00007671192,0.00004030812],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012543657,0.0010411845,0.0013303314,0.0015277009,0.00037254216,0.001406357,0.00097114855,0.001510863,0.0046047983],"category_scores_gemma":[0.00062678143,0.000556144,0.0003890818,0.0020839137,0.0010462217,0.0027124097,0.0009798743,0.0021460126,0.0033643318],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082237064,0.0002187835,0.0001247051,0.010240301,0.000039057857,0.00025783989,0.00013113477,0.001288808,0.009555255,0.021110574,0.018034114,0.9389173],"study_design_scores_gemma":[0.000025272926,0.00018397348,0.00019924191,0.0009765071,0.00003060501,0.00096865883,0.00007547355,0.00052409765,0.0037442253,0.0056506223,0.98759174,0.00002960896],"about_ca_topic_score_codex":0.0004909823,"about_ca_topic_score_gemma":0.0007570732,"teacher_disagreement_score":0.0046047983,"about_ca_system_score_codex":0.0010238722,"about_ca_system_score_gemma":0.0008131957,"threshold_uncertainty_score":0.015404522},"labels":[],"label_agreement":null},{"id":"W2006724497","doi":"10.2174/1568026033452320","title":"Protein Tyrosine Phosphatase α (PTPα): A Src Family Kinase Activator and Mediator of Multiple Biological Effects","year":2003,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"","keywords":"Proto-oncogene tyrosine-protein kinase Src; Protein tyrosine phosphatase; Cell biology; Activator (genetics); Kinase; Tyrosine-protein kinase CSK; Phosphatase; Biology; Tyrosine kinase; Signal transduction; Regulator; Mediator; SH3 domain; Chemistry; Phosphorylation; Biochemistry; Receptor; Gene","score_opus":0.04988627676694708,"score_gpt":0.33447753555989934,"score_spread":0.2845912587929523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006724497","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000603415,0.99440384,0.00042197536,0.00026269874,0.00033461253,0.000006790598,0.00001983462,0.00002253605,0.0039243554],"genre_scores_gemma":[0.0027582212,0.99042904,0.00056716107,0.00029132652,0.00029722063,0.0000107241885,0.0000695756,0.0000030197918,0.005573681],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99992216,0.000008141974,0.00000806252,0.000016069289,0.00003596188,0.000009479099],"domain_scores_gemma":[0.99993455,0.000016578955,0.000012665254,0.0000023766688,0.000018053217,0.000015853944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023345105,0.0006555923,0.0006562036,0.00103522,0.00024591072,0.0006101839,0.00041333877,0.000654891,0.003334916],"category_scores_gemma":[0.00019430429,0.00014010876,0.00017392864,0.0014076969,0.00026354217,0.000936298,0.00033944222,0.00068745564,0.004508776],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065749475,0.000053334024,0.00017428082,0.003947991,0.000032342396,0.00032381687,0.00004218618,0.00019418084,0.006418013,0.0020481017,0.025074665,0.96162534],"study_design_scores_gemma":[0.000018304558,0.00010161031,0.0007845015,0.00046355295,0.000040123534,0.0024915836,0.000045900717,0.00006216144,0.0015243766,0.0009465232,0.99351245,0.0000088899305],"about_ca_topic_score_codex":0.00047934588,"about_ca_topic_score_gemma":0.0010307442,"teacher_disagreement_score":0.003334916,"about_ca_system_score_codex":0.00039117585,"about_ca_system_score_gemma":0.00048645682,"threshold_uncertainty_score":0.01115638},"labels":[],"label_agreement":null},{"id":"W2007374093","doi":"10.2174/1568026023393903","title":"Recent Advances in 5-HT1B / 1D Receptor Antagonists and Agonists and their Potential Therapeutic Applications","year":2002,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nuvo Pharmaceuticals (Canada)","funders":"","keywords":"Ritanserin; Ketanserin; Agonist; Sumatriptan; Receptor; 5-HT1 receptor; Pharmacology; Neuroscience; Medicine; 5-HT receptor; Psychology; Serotonin; Internal medicine; Metabotropic receptor","score_opus":0.062359300492497105,"score_gpt":0.3852375655280254,"score_spread":0.3228782650355283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007374093","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021216488,0.9923644,0.0014223504,0.0013355459,0.00031334904,0.000013961246,0.00005699467,0.000031183834,0.002340554],"genre_scores_gemma":[0.012148051,0.98101074,0.002501763,0.0015744051,0.0011350181,0.000032938362,0.00016370155,0.000006333889,0.0014269938],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99973196,0.000062430365,0.00003991377,0.000058541013,0.00007010579,0.000037066315],"domain_scores_gemma":[0.99937123,0.0002471121,0.00011383542,0.000028841785,0.00015867129,0.000080200385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009890608,0.0007521219,0.0009295408,0.00092109485,0.00018349041,0.00072454294,0.0006389043,0.0010427058,0.004397496],"category_scores_gemma":[0.00073990464,0.0002759468,0.0006400799,0.00088428403,0.00050833385,0.00096877076,0.00058894267,0.0021651841,0.0013567642],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073096494,0.00046515494,0.0006309171,0.009567217,0.00017085776,0.00047715433,0.00015927016,0.0008091001,0.023238454,0.0069781565,0.01791077,0.93886197],"study_design_scores_gemma":[0.0002678781,0.0022797524,0.0048452867,0.001474738,0.0006808034,0.002871619,0.00017116961,0.0011855946,0.011780056,0.0065663066,0.96780515,0.00007172191],"about_ca_topic_score_codex":0.0005458429,"about_ca_topic_score_gemma":0.0011345408,"teacher_disagreement_score":0.004397496,"about_ca_system_score_codex":0.0003990278,"about_ca_system_score_gemma":0.0005979443,"threshold_uncertainty_score":0.014711022},"labels":[],"label_agreement":null},{"id":"W2009266771","doi":"10.2174/156802611795429176","title":"Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening?","year":2011,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Broad Institute; Novartis Foundation","keywords":"Phenotypic screening; Disease; Phenotype; Computational biology; Medicine; Data science; Computer science; Biology; Genetics; Internal medicine; Gene","score_opus":0.49639760063199156,"score_gpt":0.43578639221368765,"score_spread":0.06061120841830392,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009266771","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13471758,0.11542642,0.5141719,0.102123484,0.0028029706,0.0015940085,0.0015254638,0.0012956936,0.1263424],"genre_scores_gemma":[0.75596774,0.086982034,0.12478832,0.0104213655,0.001736047,0.0009853467,0.00067899085,0.00021996921,0.018220201],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99631566,0.0018206498,0.00013013252,0.00024927026,0.0013095883,0.00017468847],"domain_scores_gemma":[0.99334055,0.0046467083,0.00066029245,0.00034909073,0.0007627591,0.0002405956],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007793342,0.00062173314,0.001966231,0.0017449795,0.00036032783,0.002397643,0.001068373,0.0014515414,0.007086161],"category_scores_gemma":[0.012726344,0.00025480057,0.00072512316,0.0018100291,0.0016767165,0.0038211641,0.001215374,0.0011865173,0.0015307099],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000608066,0.0005595823,0.01570229,0.0043315818,0.00040153065,0.0014759989,0.00034790533,0.023191975,0.009401291,0.16750266,0.022859478,0.7536176],"study_design_scores_gemma":[0.0007348551,0.006894544,0.035038155,0.0025852076,0.0007866773,0.005443169,0.003354424,0.09806523,0.027478915,0.6435801,0.17565317,0.00038558495],"about_ca_topic_score_codex":0.0005125534,"about_ca_topic_score_gemma":0.0007878382,"teacher_disagreement_score":0.007793342,"about_ca_system_score_codex":0.00090084056,"about_ca_system_score_gemma":0.001059896,"threshold_uncertainty_score":0.0412156},"labels":[],"label_agreement":null},{"id":"W2011386695","doi":"10.2174/156802611796575902","title":"Sterol 14alpha-Demethylase (CYP51) as a Therapeutic Target for Human Trypanosomiasis and Leishmaniasis","year":2011,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Leishmaniasis; Sterol; Demethylase; Virology; Chemistry; Pharmacology; Medicine; Immunology; Biochemistry; Cholesterol","score_opus":0.16265700780894723,"score_gpt":0.4490980134472805,"score_spread":0.2864410056383333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011386695","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006018973,0.99524224,0.00030633665,0.000283511,0.00021264433,0.000010515274,0.000033621483,0.000019727238,0.0032894993],"genre_scores_gemma":[0.0030510686,0.9933363,0.00047666905,0.00020874591,0.00015999183,0.000009515183,0.00006495449,0.0000026521593,0.0026901846],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999248,0.000011774975,0.000008590996,0.000014948254,0.000030483647,0.00000940159],"domain_scores_gemma":[0.999936,0.000019589923,0.0000112378575,0.0000028440186,0.000020907686,0.000009523922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020715357,0.00054792536,0.0008405153,0.0013054799,0.00023474985,0.00052249496,0.0003742986,0.000657143,0.0042187357],"category_scores_gemma":[0.00020594437,0.00016367322,0.0002507085,0.0015656635,0.0002401448,0.0007025834,0.0003396897,0.00084426586,0.0029324954],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094151794,0.000101162455,0.00017128298,0.0094398735,0.000058330985,0.00040970696,0.000053587482,0.0003629178,0.0103898,0.0030169303,0.024304472,0.95159775],"study_design_scores_gemma":[0.0000294401,0.00016835357,0.0010437616,0.00093763036,0.00006793243,0.0018990845,0.00004800914,0.000121004065,0.0019460066,0.0011736263,0.99255145,0.000013730379],"about_ca_topic_score_codex":0.00060669036,"about_ca_topic_score_gemma":0.0013523136,"teacher_disagreement_score":0.0042187357,"about_ca_system_score_codex":0.0003533195,"about_ca_system_score_gemma":0.0005404627,"threshold_uncertainty_score":0.014113069},"labels":[],"label_agreement":null},{"id":"W2021349110","doi":"10.2174/1568026043451573","title":"Endogenous Opioids and Addiction to Alcohol and other Drugs of Abuse","year":2004,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":279,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Douglas Mental Health University Institute; McGill University","funders":"","keywords":"Nucleus accumbens; Ventral tegmental area; Endogenous opioid; Opioid; Dopamine; Addiction; Brain stimulation reward; Pharmacology; Neuroscience; Mesolimbic pathway; Opioid peptide; Dopamine receptor; Psychology; Medicine; Receptor; Internal medicine; Dopaminergic","score_opus":0.10651697363314395,"score_gpt":0.35897499948395883,"score_spread":0.2524580258508149,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021349110","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00026067684,0.99687564,0.000092089496,0.00016435132,0.00016396135,0.0000039234874,0.000009434902,0.000005264627,0.0024246552],"genre_scores_gemma":[0.0013454799,0.9959645,0.00011626205,0.00012280305,0.0001687555,0.0000058368114,0.000017655555,8.2296094e-7,0.002257867],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998895,0.000019623116,0.000012653623,0.000018885481,0.000045466226,0.000013952279],"domain_scores_gemma":[0.9999354,0.000017991153,0.000012536776,0.0000030739045,0.000019802428,0.000011182558],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019932904,0.00060432707,0.00079175975,0.0012070265,0.00033343225,0.0006032188,0.0005037676,0.0008931596,0.004697246],"category_scores_gemma":[0.00020825586,0.00014654694,0.00019569093,0.0017508643,0.00040157133,0.00070234743,0.00045366614,0.0007400429,0.0030545418],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004725707,0.0000755101,0.0004525657,0.0048791845,0.000039137045,0.0005620344,0.000089800116,0.0001492617,0.002296087,0.0033324484,0.01885528,0.9692215],"study_design_scores_gemma":[0.000009838681,0.00006986533,0.0027644045,0.0011965621,0.000033682205,0.0028714805,0.000102442245,0.00003633377,0.00047470274,0.0021364435,0.99029446,0.00000974922],"about_ca_topic_score_codex":0.0014197971,"about_ca_topic_score_gemma":0.0029442764,"teacher_disagreement_score":0.004697246,"about_ca_system_score_codex":0.00044809215,"about_ca_system_score_gemma":0.00076730666,"threshold_uncertainty_score":0.01571381},"labels":[],"label_agreement":null},{"id":"W2031282520","doi":"10.2174/1568026023393110","title":"Flexible and Frozen Sugar-Modified Nucleic Acids - Modulation of Biological Activity Through Furanose Ring Dynamics in the Antisense Strand","year":2002,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"RNase H; RNase P; Nucleic acid; RNA; Oligonucleotide; Sense (electronics); Biochemistry; Transcription (linguistics); DNA; Nucleic acid structure; Ribonuclease; Chemistry; Biology; Computational biology; Cell biology; Gene","score_opus":0.06896215209114633,"score_gpt":0.34758382037451413,"score_spread":0.2786216682833678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031282520","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09071194,0.8831169,0.010228884,0.00031941463,0.00024640845,0.000040046514,0.00007488698,0.00007289226,0.015188779],"genre_scores_gemma":[0.24688801,0.7262274,0.009786642,0.0003008507,0.00010890813,0.00006025736,0.000121083656,0.000016281929,0.01649057],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99996424,0.0000061605965,0.000002697692,0.00000875604,0.000012966666,0.0000051535944],"domain_scores_gemma":[0.99998,0.0000081202425,0.0000051120333,0.0000015066145,0.0000033327824,0.00000190237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012433238,0.00029492058,0.0003038716,0.00023750436,0.00009893966,0.00024014528,0.00024137313,0.0003259789,0.0005373373],"category_scores_gemma":[0.00008748239,0.00012036512,0.00013018852,0.00030014038,0.00020284225,0.0003519734,0.00012801588,0.00025260905,0.00041665055],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015003572,0.000054135126,0.00021953706,0.0026050056,0.000022857661,0.0005204258,0.00009861932,0.0018841035,0.56126,0.0075597325,0.00079709745,0.42482847],"study_design_scores_gemma":[0.0000408432,0.0012511351,0.0023780116,0.0003430722,0.00006621829,0.0037052664,0.00012619609,0.0016513149,0.6058427,0.003466222,0.38107595,0.000053005755],"about_ca_topic_score_codex":0.0003875607,"about_ca_topic_score_gemma":0.00059679366,"teacher_disagreement_score":0.0005373373,"about_ca_system_score_codex":0.00029158682,"about_ca_system_score_gemma":0.00015498,"threshold_uncertainty_score":0.0021156073},"labels":[],"label_agreement":null},{"id":"W2041787141","doi":"10.2174/1568026013395623","title":"Structural Biology of Bacterial Iron Uptake Systems","year":2001,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Periplasmic space; Bacterial outer membrane; Siderophore; Biochemistry; Biology; Escherichia coli; Bacteria; Serratia marcescens; Membrane protein; Iron-binding proteins; Membrane transport protein; Transport protein; Heme; Inner membrane; Microbiology; Chemistry; Transferrin; Membrane; Gene","score_opus":0.03907339219779003,"score_gpt":0.3328457818495502,"score_spread":0.29377238965176017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041787141","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87330455,0.0356048,0.041210204,0.0063446453,0.00061181217,0.000117923686,0.0005834452,0.00088683906,0.041335683],"genre_scores_gemma":[0.97659665,0.0066257464,0.008273057,0.00048672582,0.00009335248,0.00006985027,0.0010122658,0.000055963785,0.00678631],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998306,0.000027423452,0.0000088301595,0.000032530086,0.00006343126,0.000037228623],"domain_scores_gemma":[0.9998522,0.000023691424,0.00002145418,0.0000124202925,0.000051343643,0.000038824466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019599812,0.00039405067,0.0003304418,0.000323148,0.0008288836,0.0007925772,0.0006187025,0.00090542325,0.0013469901],"category_scores_gemma":[0.00038604482,0.00028667747,0.00019686266,0.00027091507,0.0005033248,0.0006778102,0.0004450856,0.000901408,0.001218318],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014291922,0.00012533416,0.0014278156,0.0007374528,0.00003183089,0.00039235587,0.00048355383,0.0095821405,0.9035717,0.05531733,0.003284792,0.02490275],"study_design_scores_gemma":[0.00011554358,0.0011954638,0.011012816,0.0002250231,0.00005524946,0.0028806997,0.0010815964,0.09974026,0.5558109,0.105659574,0.22207148,0.00015134203],"about_ca_topic_score_codex":0.0007987497,"about_ca_topic_score_gemma":0.0003800682,"teacher_disagreement_score":0.0013469901,"about_ca_system_score_codex":0.0011762958,"about_ca_system_score_gemma":0.00037560935,"threshold_uncertainty_score":0.00853467},"labels":[],"label_agreement":null},{"id":"W2054916058","doi":"10.2174/1568026023394470","title":"Multivariate Pharmaceutical Profiling for Drug Discovery","year":2002,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Profiling (computer programming); Drug discovery; Drug; Computer science; Computational biology; Data science; Medicine; Pharmacology; Bioinformatics; Biology","score_opus":0.16243778127555472,"score_gpt":0.46495256846766436,"score_spread":0.30251478719210967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054916058","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013583157,0.74267805,0.20016396,0.0056969,0.0018109209,0.00017285046,0.00033333848,0.0010100352,0.04677569],"genre_scores_gemma":[0.030183554,0.79978466,0.1430779,0.0026256219,0.0023762109,0.0003422179,0.0005108918,0.0001647072,0.020934252],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99860007,0.00049805467,0.00007063004,0.00015841433,0.0006243384,0.000048467406],"domain_scores_gemma":[0.9991136,0.0004730017,0.0000880921,0.00012620441,0.00015875645,0.00004028399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017803523,0.0012720744,0.0018265228,0.0021993313,0.00050541875,0.0021014872,0.0012294188,0.001512,0.00859227],"category_scores_gemma":[0.002545185,0.00036819244,0.0006036999,0.0048330664,0.0015354567,0.0024125022,0.0012700078,0.002349099,0.0063104434],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006532187,0.00007498465,0.0003506243,0.0034612752,0.00009677682,0.00013962509,0.00006959461,0.0055381036,0.0032153055,0.12470126,0.03876753,0.8235195],"study_design_scores_gemma":[0.000024972458,0.00011186191,0.0007076009,0.00088569435,0.000050023213,0.00077770394,0.00005452157,0.0069417553,0.002898764,0.094727956,0.8927628,0.000056411714],"about_ca_topic_score_codex":0.0011636916,"about_ca_topic_score_gemma":0.0011670758,"teacher_disagreement_score":0.00859227,"about_ca_system_score_codex":0.0013479372,"about_ca_system_score_gemma":0.0015241657,"threshold_uncertainty_score":0.028744042},"labels":[],"label_agreement":null},{"id":"W2060292828","doi":"10.2174/1568026033452276","title":"Protein Tyrosine Phosphatase 1B: A Novel Target for Type 2 Diabetes and Obesity","year":2003,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Autophosphorylation; Insulin receptor; Insulin; Endocrinology; Internal medicine; Protein tyrosine phosphatase; Type 2 diabetes; IRS2; Glucose homeostasis; Phosphorylation; Biology; Insulin receptor substrate; Insulin-like growth factor 1 receptor; Diabetes mellitus; Receptor; Medicine; Insulin resistance; Cell biology; Protein kinase A","score_opus":0.04656700247953985,"score_gpt":0.34206484218686695,"score_spread":0.2954978397073271,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060292828","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00036785394,0.9969081,0.0004455258,0.0005060233,0.00035554543,0.0000057925154,0.000015271,0.000015069328,0.0013807539],"genre_scores_gemma":[0.0020897316,0.99434364,0.00052538194,0.0003688574,0.0003247752,0.000010347117,0.00004103537,0.000002482221,0.0022938072],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99991524,0.0000114283375,0.0000072068547,0.000017958117,0.00003744493,0.000010781979],"domain_scores_gemma":[0.999931,0.000014608377,0.00001170226,0.0000028532681,0.000021513202,0.000018387884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003091714,0.00075965567,0.0010016952,0.0010726623,0.00023352116,0.00052391196,0.0005616741,0.00095734274,0.0032555969],"category_scores_gemma":[0.00018064772,0.0001856717,0.00021400547,0.0010246622,0.00034445446,0.00079004624,0.0003921249,0.0012105923,0.0036560877],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001232243,0.00010153141,0.00024417357,0.0050763534,0.00005340766,0.0006902444,0.000047059064,0.0003214493,0.010296085,0.004691136,0.034384917,0.9439704],"study_design_scores_gemma":[0.00005722493,0.00012256396,0.000993658,0.0005450738,0.000049326834,0.0029321287,0.000034656085,0.00012947273,0.001535312,0.0024594495,0.99112797,0.000013220797],"about_ca_topic_score_codex":0.0004453097,"about_ca_topic_score_gemma":0.0010648937,"teacher_disagreement_score":0.0032555969,"about_ca_system_score_codex":0.00042060873,"about_ca_system_score_gemma":0.00059956044,"threshold_uncertainty_score":0.01089108},"labels":[],"label_agreement":null},{"id":"W2061068674","doi":"10.2174/1568026043387953","title":"Sulfonamide-Based Acyclic and Conformationally Constrained MMP Inhibitors: From Computer-Assisted Design to Nanomolar Compounds","year":2004,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Synthesis and Catalytic Reactions","field":"Chemistry","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Servier","keywords":"Enantiopure drug; Pyrrolidine; Aziridine; Sulfonamide; Chemistry; Hydroxamic acid; Combinatorial chemistry; Tetrahydrofuran; Peptidomimetic; Docking (animal); Stereochemistry; Enantioselective synthesis; Organic chemistry; Biochemistry; Medicine; Ring (chemistry)","score_opus":0.06005045694330871,"score_gpt":0.321949288407082,"score_spread":0.26189883146377324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061068674","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007929,0.97231805,0.010464953,0.00039870886,0.00019634205,0.00008220465,0.00006637908,0.00017389619,0.008370521],"genre_scores_gemma":[0.024638103,0.9581799,0.010809412,0.00028494382,0.00012638423,0.00009458125,0.00013690504,0.000017597178,0.0057121394],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99990547,0.000013477188,0.0000096304175,0.000019975385,0.000038765305,0.000012681564],"domain_scores_gemma":[0.9999503,0.000014684198,0.00000850813,0.0000041149383,0.000014625848,0.000007735564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032878952,0.00083823333,0.0009054431,0.0009702186,0.00016863138,0.0007767969,0.000884651,0.0004368259,0.0019131765],"category_scores_gemma":[0.00021758217,0.00034130237,0.00024654716,0.0009622222,0.00043388084,0.0007695789,0.00036467574,0.0008573005,0.0020199914],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016962933,0.00025065025,0.00015126722,0.0054253256,0.00005592624,0.00032658264,0.00010803005,0.007925159,0.046642244,0.012853433,0.0070895012,0.9190024],"study_design_scores_gemma":[0.00016863216,0.00069969724,0.0007226577,0.0007113621,0.00008326152,0.0016029126,0.00006615594,0.004468483,0.047494996,0.0062414682,0.9376804,0.00005990803],"about_ca_topic_score_codex":0.0007754069,"about_ca_topic_score_gemma":0.0012197288,"teacher_disagreement_score":0.0019131765,"about_ca_system_score_codex":0.0006614449,"about_ca_system_score_gemma":0.0003778266,"threshold_uncertainty_score":0.006400287},"labels":[],"label_agreement":null},{"id":"W2073025150","doi":"10.2174/156802611795347582","title":"Molecular Biology of Nucleoside Transporters and their Distributions and Functions in the Brain","year":2011,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Manitoba","funders":"Canadian Institutes of Health Research; British Heart Foundation; Wellcome Trust","keywords":"Nucleoside; Purine; Transporter; Biology; Nucleoside transporter; Adenosine; Nucleotide; Biochemistry; Function (biology); Cell biology; Gene; Enzyme","score_opus":0.034330796969730265,"score_gpt":0.3262579335307929,"score_spread":0.2919271365610626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073025150","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016962787,0.969302,0.006668207,0.0012519717,0.0002155981,0.000026217349,0.00016981855,0.00010740188,0.0052960105],"genre_scores_gemma":[0.04513944,0.9455753,0.0039334,0.00039169533,0.00036905525,0.00004797767,0.0003219152,0.000014241129,0.004206915],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999915,0.000010634443,0.0000094549705,0.000024584251,0.00002425149,0.000016113923],"domain_scores_gemma":[0.99994695,0.000009812885,0.000012531637,0.0000015955453,0.000018726763,0.000010348491],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019907072,0.0004312708,0.0005215878,0.0007490923,0.000232491,0.00096443505,0.00040215463,0.00075621484,0.0010310576],"category_scores_gemma":[0.0001335794,0.00020648488,0.00035644916,0.00060029316,0.00030631432,0.0014182215,0.00023790573,0.0008865462,0.0006345834],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043782408,0.00011754402,0.002029381,0.006322884,0.00018693859,0.0021370417,0.00041234668,0.0016586507,0.5059958,0.045834217,0.013007388,0.42186004],"study_design_scores_gemma":[0.00004984269,0.0006688164,0.019052543,0.0012204219,0.00040519133,0.014507655,0.00051723275,0.0043536075,0.15317456,0.031678863,0.77421796,0.00015332467],"about_ca_topic_score_codex":0.0009796633,"about_ca_topic_score_gemma":0.0011331247,"teacher_disagreement_score":0.0010310576,"about_ca_system_score_codex":0.00081445393,"about_ca_system_score_gemma":0.0005721805,"threshold_uncertainty_score":0.0059093237},"labels":[],"label_agreement":null},{"id":"W2074936715","doi":"10.2174/156802609787521580","title":"Drug Transport Across the Blood-Brain Barrier and the Impact of Breast Cancer Resistance Protein (ABCG2)","year":2009,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development","funders":"","keywords":"Abcg2; Blood–brain barrier; P-glycoprotein; Efflux; Pharmacology; Drug; Transporter; ATP-binding cassette transporter; Drug resistance; Drug discovery; Paracellular transport; Biology; Multiple drug resistance; Medicine; Central nervous system; Neuroscience; Bioinformatics; Biochemistry; Permeability (electromagnetism)","score_opus":0.01903273739826056,"score_gpt":0.35579912867439234,"score_spread":0.3367663912761318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074936715","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012238303,0.9965307,0.00028626368,0.0005097627,0.00013999024,0.000005909506,0.00004649366,0.000010379561,0.0012467488],"genre_scores_gemma":[0.007063099,0.990845,0.0003202625,0.00035357385,0.00016660697,0.00001177849,0.00009235302,0.0000028070147,0.0011444808],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997284,0.00005731492,0.00004797425,0.00004663671,0.000083301464,0.00003626934],"domain_scores_gemma":[0.9997837,0.00009433308,0.000040886738,0.000005171839,0.00006710872,0.00000878574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038926487,0.00040716885,0.0009955405,0.0009944314,0.00016834716,0.0010164914,0.00042815006,0.00078122166,0.0019753822],"category_scores_gemma":[0.00059459015,0.00018888731,0.00051308714,0.0013697637,0.00034190144,0.0008952897,0.0002988592,0.00094983325,0.00090256525],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033088535,0.00007530506,0.0014647823,0.045369472,0.00027798154,0.0018533958,0.00029414834,0.0014859873,0.038413383,0.010443323,0.032681216,0.8673101],"study_design_scores_gemma":[0.00002060298,0.00032208755,0.004846776,0.0020522324,0.00029986235,0.00519272,0.00013661165,0.00034075254,0.009874319,0.0015378942,0.9753387,0.00003747785],"about_ca_topic_score_codex":0.0013806518,"about_ca_topic_score_gemma":0.002034662,"teacher_disagreement_score":0.0019753822,"about_ca_system_score_codex":0.00062964787,"about_ca_system_score_gemma":0.00076962216,"threshold_uncertainty_score":0.0066083074},"labels":[],"label_agreement":null},{"id":"W2079295573","doi":"10.2174/156802610793176648","title":"Strategies for the Discovery and Advancement of Novel Cationic Antimicrobial Peptides","year":2010,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Antimicrobial peptides; Antimicrobial; In silico; Peptide; Biology; Cathelicidin; Computational biology; Microbiology; Biochemistry","score_opus":0.04742005158298743,"score_gpt":0.3420176079674309,"score_spread":0.2945975563844435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079295573","genre_codex":"methods","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24873504,0.22338507,0.50025433,0.006300684,0.0008369736,0.0015734188,0.0007858029,0.0007947485,0.017333932],"genre_scores_gemma":[0.5176576,0.19115378,0.27632624,0.0029525687,0.00030631974,0.0011671206,0.0010757453,0.00010005705,0.0092604915],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99954647,0.000118869655,0.000035398265,0.00007312879,0.00017952788,0.000046585024],"domain_scores_gemma":[0.9997397,0.00008489502,0.00005523287,0.000021299205,0.0000700192,0.000028853958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013754416,0.0007907068,0.000741117,0.00070027617,0.00021355499,0.001224792,0.00052221114,0.0007109183,0.0015952096],"category_scores_gemma":[0.0007839421,0.000342593,0.0007171739,0.0005030708,0.0005831565,0.0012917892,0.0008294133,0.0018190987,0.0008160617],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017991231,0.000261092,0.00053346844,0.0021362905,0.00006676924,0.0003490315,0.00014445047,0.0053440486,0.87510026,0.010381844,0.001109643,0.10439321],"study_design_scores_gemma":[0.00024508883,0.0050695683,0.0013744993,0.00056348095,0.0001987997,0.001677821,0.00022522187,0.016946945,0.81041235,0.0099328915,0.1532504,0.00010299949],"about_ca_topic_score_codex":0.0002418389,"about_ca_topic_score_gemma":0.00035455683,"teacher_disagreement_score":0.0015952096,"about_ca_system_score_codex":0.00062971236,"about_ca_system_score_gemma":0.0007073447,"threshold_uncertainty_score":0.0072740912},"labels":[],"label_agreement":null},{"id":"W2079534288","doi":"10.2174/1568026033452311","title":"Inhibitors of Protein Tyrosine Phosphatase 1B (PTP1B)","year":2003,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Protein tyrosine phosphatase; Phosphatase; Insulin; Tyrosine; Diabetes mellitus; Insulin receptor; Computational biology; Chemistry; Medicine; Biochemistry; Enzyme; Biology; Internal medicine; Endocrinology; Insulin resistance","score_opus":0.0314126420675822,"score_gpt":0.3344851856915182,"score_spread":0.303072543623936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079534288","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004507916,0.99657947,0.00058164226,0.0001477587,0.00018939908,0.000011022992,0.00002134488,0.000024920635,0.0019935751],"genre_scores_gemma":[0.0020480074,0.99484634,0.0006011982,0.00017569483,0.00013765572,0.000012442391,0.00005096945,0.0000023186365,0.0021254183],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99984586,0.000015405154,0.000014543665,0.000036153626,0.00007008396,0.000017925699],"domain_scores_gemma":[0.9998648,0.000042490152,0.000030885632,0.0000061750648,0.00003267005,0.000022934113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039903825,0.0010610704,0.0010895935,0.001612715,0.0002343947,0.0005265318,0.00067022844,0.0006961726,0.0030924424],"category_scores_gemma":[0.0003507334,0.00021176075,0.00029947897,0.0015797608,0.00029217036,0.0008436229,0.00055142905,0.0011330163,0.003762517],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008358059,0.00012990256,0.00016547112,0.0054464117,0.00005153004,0.00028510604,0.000030635914,0.00028684197,0.0115432665,0.0014099701,0.014380522,0.9661867],"study_design_scores_gemma":[0.000050699036,0.0002764922,0.0011936538,0.00076487113,0.00010576669,0.0031870026,0.000029778346,0.00010559073,0.0064678704,0.0010069693,0.986791,0.000020223231],"about_ca_topic_score_codex":0.00045483917,"about_ca_topic_score_gemma":0.0009054603,"teacher_disagreement_score":0.0030924424,"about_ca_system_score_codex":0.00038500564,"about_ca_system_score_gemma":0.00034431263,"threshold_uncertainty_score":0.010345221},"labels":[],"label_agreement":null},{"id":"W2083174947","doi":"10.2174/156802608785848987","title":"Recent Trends in Glycodendrimer Syntheses and Applications","year":2008,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":214,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Glycoconjugate; Glycan; Avidity; Chemistry; Computational biology; Glycobiology; Bacterial adhesin; Glycopeptide; Click chemistry; Mechanism (biology); Drug discovery; Dendrimer; Biology; Cell biology; Biochemistry; Combinatorial chemistry; Antigen; Glycoprotein; Virulence; Gene; Immunology","score_opus":0.07631292395456554,"score_gpt":0.4002602200124858,"score_spread":0.3239472960579203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083174947","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004744789,0.98402923,0.0047515994,0.00038008209,0.00024540658,0.000026550913,0.00004478423,0.00005967311,0.005717926],"genre_scores_gemma":[0.009718401,0.98284507,0.004248533,0.00028953032,0.00023149108,0.000027707716,0.00008904381,0.000010829388,0.0025394296],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998024,0.000028493163,0.000022583712,0.000050379425,0.00007743111,0.000018798648],"domain_scores_gemma":[0.9997571,0.00009315223,0.00005814826,0.00001611396,0.00005024989,0.000025227095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071767165,0.0008925994,0.00075751636,0.0013222238,0.00022912539,0.0007240067,0.0007175783,0.0006282344,0.0029888148],"category_scores_gemma":[0.00052742084,0.00043736922,0.0003859565,0.0019250839,0.00043859522,0.0013736894,0.00047100708,0.0010563517,0.0021062263],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016261349,0.0001740334,0.00022368762,0.009647123,0.00005078324,0.00032199285,0.000116906034,0.0025310256,0.061373748,0.0071438085,0.0059428103,0.91231143],"study_design_scores_gemma":[0.000043845204,0.00049188366,0.00078004366,0.000722999,0.00009871053,0.0017721283,0.00008202362,0.0011222505,0.049836896,0.0033204728,0.9416871,0.000041623],"about_ca_topic_score_codex":0.00044091255,"about_ca_topic_score_gemma":0.0005685759,"teacher_disagreement_score":0.0029888148,"about_ca_system_score_codex":0.0006574628,"about_ca_system_score_gemma":0.00052748923,"threshold_uncertainty_score":0.00999856},"labels":[],"label_agreement":null},{"id":"W2089063761","doi":"10.2174/156802605774643015","title":"Bioactive C-Glycosides from Bacterial Secondary Metabolism","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":143,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Glycosidic bond; Biosynthesis; Glycoside; Glycosyltransferase; Streptomyces; Bacteria; Chemistry; Biochemistry; Computational biology; Biology; Gene; Stereochemistry; Genetics; Enzyme","score_opus":0.05249884151208032,"score_gpt":0.33225797118933825,"score_spread":0.2797591296772579,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089063761","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0043541165,0.96672374,0.0028325913,0.00029496607,0.00039602225,0.000037913764,0.00011991264,0.000072604635,0.02516811],"genre_scores_gemma":[0.014326847,0.97440547,0.0020735268,0.00020559184,0.00019023007,0.000025917505,0.00021605924,0.000008530351,0.0085479],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99994016,0.0000058537707,0.000005206312,0.000011401723,0.000029774203,0.0000075733046],"domain_scores_gemma":[0.9999639,0.0000069729895,0.000006615848,0.000002416454,0.000011508254,0.000008609951],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013844034,0.0007460521,0.00057310483,0.0010584258,0.00024132388,0.0006492801,0.00028754107,0.00040673686,0.0035835498],"category_scores_gemma":[0.00012570065,0.00015075387,0.00019230835,0.0012526988,0.00021434811,0.00060197816,0.0003459194,0.00059957587,0.0051815757],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064849264,0.000060577564,0.00015040321,0.005303226,0.000023412755,0.00045440084,0.00005546904,0.0005716867,0.07003222,0.006808054,0.0077376803,0.90873814],"study_design_scores_gemma":[0.000015125245,0.00016472934,0.0010314517,0.00076287665,0.00002893905,0.0020125161,0.000050889492,0.00014671199,0.027161468,0.0031725685,0.9654331,0.000019563371],"about_ca_topic_score_codex":0.0003328755,"about_ca_topic_score_gemma":0.0006069092,"teacher_disagreement_score":0.0035835498,"about_ca_system_score_codex":0.00041136766,"about_ca_system_score_gemma":0.00047881863,"threshold_uncertainty_score":0.011988163},"labels":[],"label_agreement":null},{"id":"W2089754323","doi":"10.2174/1568026611313030012","title":"Multiple Roles of Transient Receptor Potential (TRP) Channels in Inflammatory Conditions and Current Status of Drug Development","year":2013,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Interdisciplinary Research in Rehabilitation","funders":"","keywords":"Transient receptor potential channel; Drug development; Transient (computer programming); Current (fluid); Drug; Pharmacology; Chemistry; Receptor; Medicine; Computer science; Biochemistry; Physics","score_opus":0.05170860681470074,"score_gpt":0.3319444697217915,"score_spread":0.28023586290709074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089754323","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004469788,0.99648523,0.0004944668,0.00040084272,0.00017919138,0.0000072370485,0.00003232273,0.000019506722,0.0019341959],"genre_scores_gemma":[0.0017540122,0.9964768,0.00045465183,0.00020306227,0.00018729553,0.0000075165544,0.000041830324,0.0000026479033,0.00087220216],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998142,0.000027861175,0.000025809404,0.000041937932,0.00006541656,0.00002471463],"domain_scores_gemma":[0.9997303,0.00011503575,0.000041644835,0.000010257278,0.00006984327,0.000032942018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055338594,0.00068089203,0.001239617,0.0020275337,0.00028801354,0.0008883113,0.0007066746,0.0008623242,0.005042471],"category_scores_gemma":[0.00049488456,0.00024230142,0.0004582738,0.0020807427,0.00050526654,0.0017520589,0.00069451594,0.0014416772,0.0028534918],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011921927,0.000119394725,0.00019359801,0.011160634,0.000048639235,0.00030756276,0.00006972513,0.0003794469,0.0062962133,0.0051640267,0.015413548,0.960728],"study_design_scores_gemma":[0.000033426393,0.00036500173,0.000867345,0.002154564,0.00014035948,0.0020632118,0.00010960248,0.00034933857,0.0031319752,0.0049534487,0.9857939,0.00003784038],"about_ca_topic_score_codex":0.00042279574,"about_ca_topic_score_gemma":0.0008354524,"teacher_disagreement_score":0.005042471,"about_ca_system_score_codex":0.00045265036,"about_ca_system_score_gemma":0.00088328443,"threshold_uncertainty_score":0.01686871},"labels":[],"label_agreement":null},{"id":"W2099524467","doi":"10.2174/156802606776287054","title":"Targeting Serine Proteases in Asthma","year":2006,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Proteases; Asthma; Serine; Medicine; Chemistry; Biochemistry; Immunology; Enzyme","score_opus":0.02535599580841364,"score_gpt":0.3353388599392942,"score_spread":0.30998286413088055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099524467","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010564276,0.9946833,0.0007348757,0.00024592783,0.0002080521,0.000014151778,0.000026224272,0.000036897705,0.0029942018],"genre_scores_gemma":[0.0048245876,0.98965704,0.001149455,0.00023983307,0.00016331612,0.000017323533,0.000059019076,0.0000047406993,0.0038846922],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999069,0.0000123415075,0.000009925678,0.000017176057,0.00004097809,0.000012643724],"domain_scores_gemma":[0.9999597,0.0000095836895,0.0000094209645,0.0000024416777,0.000011073045,0.00000775857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000251262,0.00074689754,0.0008046458,0.0011677353,0.00022994587,0.00050351815,0.00046517956,0.0008109076,0.0028259098],"category_scores_gemma":[0.0001356171,0.00023217159,0.00024239179,0.0010409832,0.0002909667,0.00061575556,0.0003979304,0.0010296224,0.0036800697],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015928499,0.00017270872,0.00014699511,0.006904105,0.00004919932,0.00052818935,0.00006583603,0.0007005656,0.06135883,0.0044210018,0.017526798,0.9079665],"study_design_scores_gemma":[0.00006658683,0.0003381823,0.0010467945,0.0007797629,0.00006235111,0.0032287757,0.00003578475,0.00025835636,0.015331127,0.00211459,0.9767165,0.000021249372],"about_ca_topic_score_codex":0.0005327295,"about_ca_topic_score_gemma":0.00088970445,"teacher_disagreement_score":0.0028259098,"about_ca_system_score_codex":0.000498929,"about_ca_system_score_gemma":0.0003672351,"threshold_uncertainty_score":0.009453654},"labels":[],"label_agreement":null},{"id":"W2105395808","doi":"10.2174/1568026054367638","title":"Cellular Signalling Pathways of Spinal Pain Neuroplasticity as Targets for Analgesic Development","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Neuroscience; Ionotropic effect; Glutamatergic; Kainate receptor; AMPA receptor; NMDA receptor; Nociception; Glutamate receptor; Neurotransmission; Microglia; Synaptic plasticity; Biology; Receptor; Medicine; Internal medicine; Inflammation","score_opus":0.09331946387860961,"score_gpt":0.3626373062188595,"score_spread":0.26931784234024986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105395808","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034416618,0.99652404,0.00039658527,0.00020576859,0.0001591056,0.000010091723,0.00001400779,0.000013385397,0.0023328469],"genre_scores_gemma":[0.0016497186,0.99623704,0.00047007116,0.0001456182,0.000111296285,0.000013946209,0.00002615565,0.0000013354777,0.001344839],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99987555,0.000023712637,0.000014173866,0.00001854131,0.00005060901,0.000017311615],"domain_scores_gemma":[0.9999187,0.00002714158,0.00001322331,0.0000038800486,0.000026382446,0.000010669652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004163218,0.0009467834,0.0013934267,0.0016586329,0.00031483843,0.00090514205,0.0010850127,0.0010520036,0.0036389073],"category_scores_gemma":[0.00025053121,0.00025331427,0.00034440277,0.0016709493,0.0005978907,0.0013394846,0.00043787961,0.0012565335,0.0033605031],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015889505,0.00016204876,0.00016305811,0.014073222,0.00006016213,0.00078445446,0.00012787989,0.0008851078,0.019001115,0.01163506,0.017187275,0.93576163],"study_design_scores_gemma":[0.000041285657,0.00014292475,0.0010157491,0.0019871457,0.000067214074,0.0016905088,0.00009935151,0.00018148062,0.0036791204,0.00546001,0.9856135,0.000021582486],"about_ca_topic_score_codex":0.00064404827,"about_ca_topic_score_gemma":0.001002362,"teacher_disagreement_score":0.0036389073,"about_ca_system_score_codex":0.0008059676,"about_ca_system_score_gemma":0.000696161,"threshold_uncertainty_score":0.012173295},"labels":[],"label_agreement":null},{"id":"W2109893892","doi":"10.2174/1568026033392499","title":"Traditionally-Used Antimalarials from the Meliaceae","year":2003,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Phytochemical compounds biological activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Meliaceae; Azadirachta; Phytomedicine; Traditional medicine; Limonoid; Biology; Melia azedarach; Medicinal plants; Pharmacology; Botany; Medicine","score_opus":0.08628556810435459,"score_gpt":0.3572202083679681,"score_spread":0.27093464026361347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109893892","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001434287,0.9894638,0.0007699872,0.0003137637,0.00019784392,0.00001756134,0.000042034637,0.000040808372,0.007719904],"genre_scores_gemma":[0.006040111,0.9863961,0.001033949,0.00027222073,0.00016357459,0.000016376414,0.000099520985,0.0000035268383,0.0059746974],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999331,0.000008211613,0.00000782639,0.000013289747,0.000029530347,0.000007998597],"domain_scores_gemma":[0.9999541,0.000009529964,0.000008225078,0.000003275169,0.000016560032,0.000008299793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018095355,0.00076623255,0.00060994027,0.0017451954,0.00026619804,0.00060870394,0.0005209255,0.00040867864,0.0042663077],"category_scores_gemma":[0.00015826485,0.0001621087,0.00019004385,0.0015507524,0.00030716855,0.00082645135,0.00036324366,0.00060962036,0.0039000267],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066024455,0.00008896084,0.00019306852,0.006001485,0.000028399338,0.00028571556,0.000052344327,0.0002127999,0.018321082,0.0022437954,0.007848674,0.96465766],"study_design_scores_gemma":[0.000020379655,0.00010643426,0.0013473105,0.000478606,0.000028698018,0.0016299163,0.000047987312,0.000056112272,0.0034816605,0.0011418065,0.9916528,0.000008367352],"about_ca_topic_score_codex":0.00070541026,"about_ca_topic_score_gemma":0.0015999867,"teacher_disagreement_score":0.0042663077,"about_ca_system_score_codex":0.000461103,"about_ca_system_score_gemma":0.00045525623,"threshold_uncertainty_score":0.014272273},"labels":[],"label_agreement":null},{"id":"W2115654034","doi":"10.2174/1568026023394641","title":"Applications of Computer Software for the Interpretation and Management of Mass Spectrometry Data in Pharmaceutical Science","year":2002,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Analytical Chemistry and Chromatography","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"","keywords":"Bottleneck; Computer science; Timeline; Software; Focus (optics); Throughput; Data mining; Data science; Operating system; Embedded system","score_opus":0.07812879178447274,"score_gpt":0.40502053070782396,"score_spread":0.3268917389233512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115654034","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0035246774,0.58075136,0.37689647,0.0026604063,0.0015979451,0.0005543758,0.00033181426,0.003057656,0.030625377],"genre_scores_gemma":[0.013942845,0.53239256,0.43856433,0.0017809952,0.0011415317,0.00041155075,0.0007894071,0.00043561167,0.01054122],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99679357,0.00074490986,0.0004096178,0.00038706532,0.0015653558,0.00009959134],"domain_scores_gemma":[0.99619126,0.0022952538,0.00019831018,0.00038376622,0.00082114706,0.000110216366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004007333,0.0013634689,0.0012920297,0.0042404556,0.00064765837,0.0023683142,0.0022876172,0.0017061513,0.0042727254],"category_scores_gemma":[0.0058550797,0.0006473255,0.0008411811,0.006961561,0.0016337375,0.00333982,0.0014491583,0.0023878112,0.0061984127],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003749743,0.000072536306,0.0004288915,0.0030758202,0.0000536707,0.00021282757,0.00014207527,0.0011097483,0.0053879377,0.009611819,0.011662762,0.9682044],"study_design_scores_gemma":[0.00004330154,0.00018626968,0.0021779344,0.002720879,0.0001418513,0.0031557088,0.00014670828,0.0069519943,0.01363856,0.034084287,0.936631,0.000121501376],"about_ca_topic_score_codex":0.001441164,"about_ca_topic_score_gemma":0.0012417147,"teacher_disagreement_score":0.0042727254,"about_ca_system_score_codex":0.0009930582,"about_ca_system_score_gemma":0.0016126451,"threshold_uncertainty_score":0.021193087},"labels":[],"label_agreement":null},{"id":"W2118971711","doi":"10.2174/156802610791113469","title":"Therapeutic Utility and Medicinal Chemistry of Cathepsin C Inhibitors","year":2010,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Proteases; Cathepsin C; Cathepsin G; Chemistry; Cathepsin; Biochemistry; Serine; Serine protease; Pharmacology; Serine Proteinase Inhibitors; Protease; Enzyme; Biology","score_opus":0.059119748744363626,"score_gpt":0.3784413533144509,"score_spread":0.3193216045700873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118971711","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21029375,0.65179276,0.034263823,0.0042217034,0.0010795626,0.00035449705,0.0014861538,0.00045064194,0.096057154],"genre_scores_gemma":[0.710152,0.26617354,0.0074719475,0.0015050003,0.00037995615,0.00015759117,0.00077351695,0.00003321521,0.013353275],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99982125,0.000044520686,0.000009052778,0.000038054786,0.000048978036,0.00003816302],"domain_scores_gemma":[0.99991834,0.000015484751,0.000022046419,0.000008065103,0.000019826428,0.000016249034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003617685,0.00057977525,0.0003018677,0.00058188505,0.00019639263,0.0006820087,0.00033284692,0.00052606803,0.0018226833],"category_scores_gemma":[0.00027913295,0.00020366491,0.00032547803,0.0003732967,0.00036160176,0.00042536866,0.00039649865,0.0010876023,0.0007267053],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011387388,0.0007907007,0.00051778875,0.0031353107,0.0001353372,0.00093950215,0.00017067403,0.008990619,0.56623614,0.032466367,0.010733041,0.37474582],"study_design_scores_gemma":[0.00053347036,0.00700922,0.002536935,0.0005163897,0.00015611279,0.0035172831,0.00008785022,0.005746041,0.51588523,0.007396983,0.45650622,0.0001082378],"about_ca_topic_score_codex":0.0004050267,"about_ca_topic_score_gemma":0.0005026627,"teacher_disagreement_score":0.0018226833,"about_ca_system_score_codex":0.0005426619,"about_ca_system_score_gemma":0.00027278534,"threshold_uncertainty_score":0.0060974956},"labels":[],"label_agreement":null},{"id":"W2124252984","doi":"10.2174/1568026054367629","title":"Role of Cation-Chloride-Cotransporters (CCC) in Pain and Hyperalgesia","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":197,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; McGill University","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Cotransporter; GABAergic; Inhibitory postsynaptic potential; Chemistry; Nociception; Neuroscience; Depolarization; Nociceptor; Spinal cord; Glycine receptor; Hyperalgesia; Pharmacology; Biophysics; Cell biology; Biochemistry; Medicine; Biology; Glycine; Receptor; Sodium","score_opus":0.0385513509255555,"score_gpt":0.3408740506435239,"score_spread":0.3023226997179684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124252984","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00035477983,0.99786997,0.00023923045,0.00016072695,0.00017197944,0.000004552022,0.000008705181,0.000010345153,0.001179731],"genre_scores_gemma":[0.003145633,0.9947896,0.0003057436,0.00017680423,0.00017007443,0.0000062948516,0.000020304184,0.0000013830063,0.0013841037],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99989104,0.000016637152,0.0000149083,0.000018218101,0.00004366017,0.00001550793],"domain_scores_gemma":[0.99989784,0.000029032763,0.00001904411,0.0000033860308,0.00003396414,0.000016643868],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030216252,0.0006731696,0.00092303683,0.0011766584,0.00028230282,0.0006516591,0.0005569062,0.0010021543,0.0025428557],"category_scores_gemma":[0.00023300918,0.00017838438,0.00025489193,0.0012925664,0.00038803447,0.00093756657,0.00040016335,0.0008024402,0.0024403518],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014284322,0.0000926873,0.0003551682,0.0089216195,0.00007096626,0.00062240456,0.00006328892,0.00046097647,0.012461604,0.003982681,0.014754159,0.95807177],"study_design_scores_gemma":[0.000042280917,0.00019311397,0.0021247494,0.0010772117,0.00010127567,0.003369134,0.00009269219,0.00023635989,0.0040177386,0.00313166,0.9855899,0.000023909071],"about_ca_topic_score_codex":0.0007813404,"about_ca_topic_score_gemma":0.0013181838,"teacher_disagreement_score":0.0025428557,"about_ca_system_score_codex":0.000447208,"about_ca_system_score_gemma":0.0006319363,"threshold_uncertainty_score":0.008506715},"labels":[],"label_agreement":null},{"id":"W2128824604","doi":"10.2174/15680266113139990004","title":"A Challenge for Medicinal Chemistry by the 17β-hydroxysteroid Dehydrogenase Superfamily: An Integrated Biological Function and Inhibition Study","year":2013,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Hydroxysteroid dehydrogenase; Enzyme; Steroid; Dehydrogenase; Dihydrotestosterone; Chemistry; Estrogen; Androgen; Prostate cancer; Receptor; Hormone; Cancer; Biochemistry; Cancer research; Biology; Endocrinology; Genetics","score_opus":0.059253587968455784,"score_gpt":0.3427177011190026,"score_spread":0.28346411315054687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128824604","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03256608,0.7658401,0.058596622,0.07435536,0.006217895,0.0002231715,0.00042705183,0.0005487776,0.061224896],"genre_scores_gemma":[0.22307736,0.6567362,0.03591992,0.024018526,0.005901661,0.00034270767,0.00078058644,0.00020745514,0.05301562],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99937326,0.00016942096,0.000028548264,0.00012580251,0.00020569301,0.000097218945],"domain_scores_gemma":[0.99956673,0.00009247725,0.000043220367,0.00005303011,0.0001479652,0.00009648446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019010875,0.0007596572,0.0010205173,0.0005416052,0.0005688342,0.0017062789,0.00090130756,0.0016967205,0.0064805215],"category_scores_gemma":[0.0010863261,0.00037221695,0.00074316404,0.0007328664,0.0014112795,0.0041936147,0.0016596825,0.004070273,0.0034080497],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036452044,0.00071394345,0.00065798336,0.0026360268,0.00012362575,0.0005504784,0.0005262725,0.0037479773,0.063366316,0.14822333,0.08425594,0.6948336],"study_design_scores_gemma":[0.00018873309,0.0018991192,0.00079222233,0.000650977,0.000065049855,0.0010385267,0.00040051047,0.0061722496,0.021532618,0.054739676,0.91243273,0.00008772385],"about_ca_topic_score_codex":0.0007249909,"about_ca_topic_score_gemma":0.0008809076,"teacher_disagreement_score":0.0064805215,"about_ca_system_score_codex":0.00116068,"about_ca_system_score_gemma":0.0013757455,"threshold_uncertainty_score":0.021679461},"labels":[],"label_agreement":null},{"id":"W2137551797","doi":"10.2174/156802612801319070","title":"DNA Repair Inhibitors: The Next Major Step to Improve Cancer Therapy","year":2012,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Allard Foundation","keywords":"ERCC1; Nucleotide excision repair; DNA repair; Base excision repair; DNA polymerase; Context (archaeology); DNA damage; Xeroderma pigmentosum; Cisplatin; Cancer; Cancer research; Bleomycin; DNA polymerase beta; Biology; DNA; Medicine; Computational biology; Bioinformatics; Genetics; Chemotherapy","score_opus":0.05511950255063542,"score_gpt":0.35533841091381213,"score_spread":0.3002189083631767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137551797","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005426078,0.9422932,0.009338953,0.020311821,0.0032888178,0.00013781819,0.0006654184,0.0004691311,0.018068781],"genre_scores_gemma":[0.025504401,0.93689865,0.008577293,0.009954068,0.0018440875,0.00012595617,0.0008134347,0.00008498475,0.016197026],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997073,0.00006277391,0.000021074244,0.000051449322,0.00010702761,0.00005030646],"domain_scores_gemma":[0.99972266,0.00007140389,0.00004499167,0.00001765918,0.000086460124,0.000056816196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007794326,0.000822147,0.0013338063,0.0009522539,0.00034087652,0.0021085348,0.0008268598,0.0014137843,0.009777563],"category_scores_gemma":[0.0006587913,0.00032138723,0.0005254709,0.00064821943,0.00061884226,0.00260824,0.00082386524,0.0039929836,0.006472575],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058525876,0.00058075524,0.0005602721,0.009812047,0.00021238755,0.0005005644,0.00018267705,0.0014906403,0.06097722,0.042644147,0.13225535,0.7501987],"study_design_scores_gemma":[0.00010970553,0.0006334802,0.00047837137,0.0007489802,0.00008626125,0.00070688524,0.00007193176,0.00051200954,0.008006711,0.0108095445,0.97779727,0.00003885308],"about_ca_topic_score_codex":0.00035212812,"about_ca_topic_score_gemma":0.00089221593,"teacher_disagreement_score":0.009777563,"about_ca_system_score_codex":0.0009152919,"about_ca_system_score_gemma":0.0009128137,"threshold_uncertainty_score":0.03270924},"labels":[],"label_agreement":null},{"id":"W2142845455","doi":"10.2174/156802606775270279","title":"Control of Chronic Inflammation with Pathway Selective Estrogen Receptor Ligands","year":2006,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Inflammation; Estrogen receptor; Estrogen; Receptor; Chemistry; Pharmacology; Medicine; Internal medicine","score_opus":0.009484579877174075,"score_gpt":0.28149467042809084,"score_spread":0.2720100905509168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142845455","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001496004,0.99380904,0.0010471857,0.00016260293,0.00013365841,0.000012445193,0.000024339868,0.000032453852,0.0032822776],"genre_scores_gemma":[0.008432123,0.98639214,0.0010588362,0.00017695298,0.00011825443,0.000023082399,0.000053820106,0.0000036396484,0.0037411682],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999229,0.000012763976,0.0000073540177,0.000013507145,0.000031735908,0.000011758861],"domain_scores_gemma":[0.99995947,0.000011597711,0.000009091297,0.0000030004169,0.0000109044695,0.0000059736067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026921183,0.0005550309,0.0008393963,0.00087038026,0.00015746613,0.00044139847,0.0005188284,0.0004535243,0.0019186677],"category_scores_gemma":[0.0001408346,0.00017634786,0.0002044798,0.00068249414,0.00027718875,0.0004929258,0.00034406423,0.0006032958,0.0022049441],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014593429,0.000101794445,0.00017955703,0.00589717,0.000052654264,0.00044076281,0.000057344463,0.0005854828,0.039565343,0.006409304,0.01078956,0.9357752],"study_design_scores_gemma":[0.00006282151,0.00023684477,0.0010780982,0.0005424019,0.000047275942,0.002049974,0.000044491248,0.00022034315,0.014265402,0.002215726,0.979219,0.000017519797],"about_ca_topic_score_codex":0.0002949023,"about_ca_topic_score_gemma":0.0005762933,"teacher_disagreement_score":0.0019186677,"about_ca_system_score_codex":0.00031673873,"about_ca_system_score_gemma":0.00027378224,"threshold_uncertainty_score":0.006418586},"labels":[],"label_agreement":null},{"id":"W2145727779","doi":"10.2174/1568026054750236","title":"Recent Advances in Non-Competitive mGlu5 Receptor Antagonists and their Potential Therapeutic Applications","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nuvo Pharmaceuticals (Canada)","funders":"","keywords":"Metabotropic glutamate receptor; Neuroscience; Metabotropic receptor; Receptor; Glutamate receptor; Metabotropic glutamate receptor 5; Pharmacology; Medicine; Biology; Internal medicine","score_opus":0.07072333692176577,"score_gpt":0.42479840370446414,"score_spread":0.3540750667826984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145727779","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0037657358,0.9872766,0.0029936049,0.0009254676,0.0003494562,0.000036325,0.000074392025,0.0000618731,0.004516537],"genre_scores_gemma":[0.013270582,0.9797712,0.0024089806,0.0010777332,0.0004925886,0.000051536343,0.00017490008,0.000011819505,0.0027406611],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99979526,0.0000426567,0.000024489866,0.000042256215,0.00006032512,0.000035158315],"domain_scores_gemma":[0.99974304,0.00008467102,0.000055843477,0.00001133466,0.00007121119,0.00003377817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007497018,0.00085476896,0.0009256904,0.0010379668,0.00020300226,0.0006515181,0.0006903398,0.00093078375,0.004516374],"category_scores_gemma":[0.00052973314,0.00035203833,0.00067676423,0.0010130304,0.00032791708,0.0011198267,0.00056421745,0.0015892923,0.0018352852],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005565227,0.00050616084,0.00032608004,0.018037029,0.00020688894,0.0007099004,0.00025489286,0.0016497811,0.06414687,0.008239035,0.02446476,0.88090223],"study_design_scores_gemma":[0.00018918431,0.0023439857,0.0016931782,0.0012551693,0.00043613202,0.0018862433,0.00013572988,0.0013620479,0.026614452,0.0033663784,0.96063054,0.00008703297],"about_ca_topic_score_codex":0.0005440167,"about_ca_topic_score_gemma":0.0011622128,"teacher_disagreement_score":0.004516374,"about_ca_system_score_codex":0.0003891996,"about_ca_system_score_gemma":0.0005619212,"threshold_uncertainty_score":0.015108764},"labels":[],"label_agreement":null},{"id":"W2160380996","doi":"10.2174/1568026614666140118213915","title":"Flow Chemistry to Control the Synthesis of Nano and Microparticles for Biomedical Applications","year":2014,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Innovative Microfluidic and Catalytic Techniques Innovation","field":"Engineering","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Nanotechnology; Microfluidics; Nano-; Nanoparticle; Flow chemistry; Microsystem; Chemistry; Materials science; Catalysis; Organic chemistry","score_opus":0.02131315098674379,"score_gpt":0.312184616119099,"score_spread":0.2908714651323552,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160380996","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017831958,0.9700493,0.01837043,0.000547447,0.0008913777,0.0000867039,0.00004557451,0.00009631622,0.008129694],"genre_scores_gemma":[0.016698733,0.95335716,0.018663645,0.00096745766,0.0006738033,0.00015106706,0.00010647948,0.00003882366,0.009342903],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997075,0.00003325099,0.000022738894,0.000076937155,0.00012984847,0.000029614544],"domain_scores_gemma":[0.9998293,0.00007382261,0.000031862975,0.0000121456005,0.000040723367,0.000012133977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008132264,0.0011696132,0.000754867,0.0019207789,0.00032403678,0.000659007,0.00066247204,0.001089304,0.0023763708],"category_scores_gemma":[0.00043289718,0.00044153398,0.00053354003,0.0012543991,0.0008725421,0.0015559462,0.0006073589,0.0019309408,0.0022618165],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005397893,0.00022262264,0.00022609501,0.014228324,0.00009604704,0.0003032479,0.00014499006,0.001657559,0.11080652,0.030294701,0.010912814,0.8310532],"study_design_scores_gemma":[0.000026530068,0.00025149243,0.00048305403,0.0009664005,0.0000739521,0.0010797518,0.000042372776,0.001030964,0.07019916,0.0045493464,0.92123586,0.000061047416],"about_ca_topic_score_codex":0.0005768267,"about_ca_topic_score_gemma":0.0007844107,"teacher_disagreement_score":0.0023763708,"about_ca_system_score_codex":0.00071162026,"about_ca_system_score_gemma":0.0006749331,"threshold_uncertainty_score":0.0079497695},"labels":[],"label_agreement":null},{"id":"W2162928407","doi":"10.2174/1568026043387836","title":"Inhibitors of 3C Cysteine Proteinases from Picornaviridae","year":2004,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Natural Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Picornavirus; Picornaviridae; Enzyme; Biochemistry; Cysteine; Rhinovirus; Biology; Chemistry; Virology; Virus; RNA; Gene","score_opus":0.08030012419379993,"score_gpt":0.41558851295304927,"score_spread":0.3352883887592493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162928407","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0033659432,0.9890021,0.0012251534,0.00014498329,0.00022342897,0.00003191945,0.00003770544,0.000054397777,0.0059142997],"genre_scores_gemma":[0.012893687,0.97928214,0.0014058644,0.00019174982,0.0001838365,0.000055303,0.00012984233,0.0000052663277,0.005852302],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99989927,0.000009628025,0.000009295065,0.000018868312,0.00005069639,0.0000122176325],"domain_scores_gemma":[0.99994683,0.000012672537,0.000011687154,0.0000027707824,0.00001675168,0.000009252788],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020650988,0.0008930596,0.0008775711,0.0014718826,0.00026059904,0.00046293883,0.00059745694,0.0005696287,0.001848646],"category_scores_gemma":[0.00017254917,0.00024055089,0.0002487288,0.0011365549,0.00025560838,0.00060897693,0.00028642776,0.0007357253,0.0018209326],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014691084,0.00017647837,0.00022586957,0.00843865,0.000054017597,0.00053473347,0.00008897303,0.0007976248,0.041785635,0.002874713,0.008922366,0.93595403],"study_design_scores_gemma":[0.00006980909,0.00045200426,0.0022603727,0.00074194116,0.00007342734,0.003160415,0.00005118864,0.0003967142,0.026850676,0.0014519556,0.9644576,0.000033981403],"about_ca_topic_score_codex":0.0005536117,"about_ca_topic_score_gemma":0.0008910673,"teacher_disagreement_score":0.001848646,"about_ca_system_score_codex":0.00039836895,"about_ca_system_score_gemma":0.00030673866,"threshold_uncertainty_score":0.0061843395},"labels":[],"label_agreement":null},{"id":"W2169673925","doi":"10.2174/1568026611313010004","title":"The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs","year":2013,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Wellcome Trust; Canadian Institutes of Health Research; Strategiske Forskningsråd","keywords":"Allosteric regulation; G protein-coupled receptor; Chemistry; Fatty acid; Computational biology; Biochemistry; Combinatorial chemistry; Biology; Receptor","score_opus":0.03752317418301737,"score_gpt":0.3281426430285333,"score_spread":0.2906194688455159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169673925","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00059006433,0.9956298,0.0004631121,0.00037978956,0.00021392603,0.000007956371,0.000025749498,0.00001880472,0.002670867],"genre_scores_gemma":[0.00234484,0.9955165,0.00041923416,0.00025972677,0.00013818315,0.000009952861,0.000035810535,0.0000023446753,0.0012734778],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998838,0.000019147279,0.000010531963,0.000020208752,0.000048484282,0.000017808989],"domain_scores_gemma":[0.9999014,0.00004373009,0.000014631955,0.000003874831,0.000024229246,0.000012111729],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036713568,0.0006017241,0.0009126738,0.0013215591,0.00024852043,0.00066636276,0.0006631372,0.0008045975,0.0034212715],"category_scores_gemma":[0.00034698917,0.0002076735,0.00040191892,0.0011279178,0.0003937206,0.0009189962,0.0005500365,0.001651158,0.0020694556],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088813074,0.000110726316,0.000125654,0.010398285,0.000057061803,0.0003262322,0.000073100804,0.0007152333,0.010909704,0.008981898,0.018677035,0.94953626],"study_design_scores_gemma":[0.000026673746,0.00017362062,0.0005729448,0.0015581757,0.000055417648,0.0015479266,0.000052761916,0.00020750893,0.0025760913,0.002911923,0.9902962,0.000020800415],"about_ca_topic_score_codex":0.0004621617,"about_ca_topic_score_gemma":0.0010504543,"teacher_disagreement_score":0.0034212715,"about_ca_system_score_codex":0.0004912967,"about_ca_system_score_gemma":0.00048539563,"threshold_uncertainty_score":0.011445284},"labels":[],"label_agreement":null},{"id":"W2169973428","doi":"10.2174/156802611795860997","title":"A New Perspective of Cannabinoid 1 Receptor Antagonists: Approaches Toward Peripheral CB1R Blockers without Crossing the Blood-Brain Barrier","year":2011,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Diet and metabolism studies","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Health Research Institutes","keywords":"Rimonabant; Cannabinoid receptor; Medicine; Endocannabinoid system; Type 2 diabetes; Anxiety; Depression (economics); Metabolic syndrome; Cannabinoid; Pharmacology; Diabetes mellitus; Receptor; Psychiatry; Internal medicine; Endocrinology; Antagonist","score_opus":0.09626445139920507,"score_gpt":0.3607005769542199,"score_spread":0.26443612555501483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169973428","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009949065,0.9937645,0.0011949963,0.0008476552,0.00033264197,0.000012774596,0.000025930913,0.000023796316,0.0028027042],"genre_scores_gemma":[0.003915571,0.9917612,0.00132242,0.00077147695,0.0003498421,0.000014891652,0.000038038594,0.0000038149446,0.0018226643],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99988544,0.000024187395,0.000013269446,0.000024573259,0.000038170056,0.000014381926],"domain_scores_gemma":[0.99991,0.000035669953,0.000013951792,0.0000035636374,0.000025334415,0.00001148218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039709118,0.00061891513,0.00093616993,0.0010793117,0.00023023896,0.0006796878,0.0006026355,0.0007992404,0.0033127877],"category_scores_gemma":[0.00022750646,0.00019604932,0.00045685426,0.0009240241,0.00041148136,0.0014483967,0.0004216941,0.0017931183,0.0019487835],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023796427,0.00024400245,0.0001674703,0.015410471,0.000088592074,0.0006471356,0.0001451001,0.0005289701,0.03730209,0.010225858,0.016721774,0.9182806],"study_design_scores_gemma":[0.00009723904,0.0007868259,0.0010252827,0.001321385,0.00014218452,0.0028573403,0.00013095306,0.00033377236,0.0070025204,0.0038963729,0.98236406,0.000042134492],"about_ca_topic_score_codex":0.00044597342,"about_ca_topic_score_gemma":0.0012897208,"teacher_disagreement_score":0.0033127877,"about_ca_system_score_codex":0.00037221695,"about_ca_system_score_gemma":0.0005660027,"threshold_uncertainty_score":0.011082411},"labels":[],"label_agreement":null},{"id":"W2280436805","doi":"10.2174/1568026615666150701113344","title":"Exploring the Technology Landscape of 7TMR Drug Signaling Profiling","year":2015,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SNC-Lavalin (Canada)","funders":"","keywords":"Drug discovery; Functional selectivity; G protein-coupled receptor; Receptor; Second messenger system; Signal transduction; Computational biology; Transmembrane protein; Arrestin; G protein; Transmembrane domain; Biology; Chemistry; Cell biology; Bioinformatics; Biochemistry","score_opus":0.10618270123454349,"score_gpt":0.3442090782645119,"score_spread":0.23802637702996843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2280436805","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00435427,0.96062094,0.0129245445,0.003672059,0.0007687539,0.00007824097,0.00019109983,0.00021368757,0.017176406],"genre_scores_gemma":[0.018916698,0.9638863,0.008101913,0.0022772208,0.00059205375,0.000095107695,0.00037571296,0.00003806959,0.0057168687],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99946004,0.00011538411,0.000040394883,0.00009750921,0.00022007282,0.00006667954],"domain_scores_gemma":[0.99949074,0.00019807454,0.00004967003,0.000022988917,0.0001918867,0.00004661762],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011886702,0.00056142575,0.00091116753,0.0015382335,0.00028150942,0.001886884,0.00093534123,0.0011079045,0.0030215096],"category_scores_gemma":[0.001240929,0.00035974383,0.00066843664,0.0010588326,0.0005377065,0.0020891977,0.0008640429,0.0023689552,0.0023178172],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013792657,0.00012627341,0.0007540665,0.0072597475,0.000089202884,0.0007762445,0.00022502575,0.0019765762,0.030368268,0.032546706,0.023848278,0.90189177],"study_design_scores_gemma":[0.00002505323,0.00045006603,0.00068210845,0.0010634304,0.00008670944,0.0015592815,0.00010113625,0.0013768658,0.012352678,0.0072945054,0.97495645,0.000051759784],"about_ca_topic_score_codex":0.0006765266,"about_ca_topic_score_gemma":0.0009432233,"teacher_disagreement_score":0.0030215096,"about_ca_system_score_codex":0.0008980835,"about_ca_system_score_gemma":0.0012972443,"threshold_uncertainty_score":0.0101079345},"labels":[],"label_agreement":null},{"id":"W2280543337","doi":"10.2174/1568026615666150413154038","title":"Outlook for Aptamers After Twenty Five Years","year":2015,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Aptamer; Nanotechnology; Computational biology; Computer science; Biology; Molecular biology; Materials science","score_opus":0.040729246974616364,"score_gpt":0.3877966872424451,"score_spread":0.3470674402678287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2280543337","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002666309,0.99307525,0.00042267214,0.0011887819,0.0010913747,0.000008192478,0.00003382269,0.000021150927,0.003892216],"genre_scores_gemma":[0.002107742,0.987755,0.0006097461,0.0017193595,0.0005863645,0.000020032312,0.000081443664,0.0000058578003,0.0071144262],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99972767,0.000042346226,0.000032799988,0.000055157197,0.00010303571,0.00003894036],"domain_scores_gemma":[0.9996413,0.00014433514,0.000043055697,0.000013930881,0.0001074761,0.000049931245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010170552,0.0009619151,0.00071540725,0.0014865509,0.00034877594,0.0011039317,0.00061119086,0.0017779269,0.007692425],"category_scores_gemma":[0.0009121004,0.0002967168,0.00049765233,0.0011433831,0.00048613144,0.0020247349,0.0010103601,0.0023757196,0.0052973875],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007699731,0.00007424168,0.00017335401,0.007607146,0.00004546261,0.00032982964,0.00011966624,0.000371023,0.0051318323,0.016034964,0.065387666,0.9046479],"study_design_scores_gemma":[0.000005214042,0.000047432648,0.0001492262,0.000748697,0.000014543784,0.00055308617,0.000024959065,0.00003213778,0.0005045369,0.0017885929,0.9961241,0.00000752239],"about_ca_topic_score_codex":0.0005377067,"about_ca_topic_score_gemma":0.0008827342,"teacher_disagreement_score":0.007692425,"about_ca_system_score_codex":0.0007671239,"about_ca_system_score_gemma":0.0008762656,"threshold_uncertainty_score":0.02573371},"labels":[],"label_agreement":null},{"id":"W2318234238","doi":"10.2174/1568026614666140202204602","title":"Fluorinated Mechanism-Based Inhibitors: Common Themes and Recent Developments","year":2014,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Synthesis and properties of polymers","field":"Materials Science","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Mechanism (biology); Computational biology; Computer science; Biology; Epistemology; Philosophy","score_opus":0.05774321393578364,"score_gpt":0.335379141755068,"score_spread":0.27763592781928437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2318234238","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027089936,0.99738675,0.00035212992,0.00029653162,0.00015752685,0.000007373126,0.000014552543,0.0000102885315,0.0015038531],"genre_scores_gemma":[0.0015473613,0.996761,0.00039794535,0.00019505079,0.00020516886,0.000008656206,0.000024467054,0.0000024721855,0.0008579191],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99975425,0.000032484077,0.000029274186,0.000054500917,0.00009862067,0.00003093926],"domain_scores_gemma":[0.999546,0.00020891572,0.00007587554,0.000014886762,0.000109525565,0.00004478617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00095925,0.0007963489,0.001112166,0.0023780004,0.00028840042,0.0014095374,0.0010263382,0.0011146681,0.0034827422],"category_scores_gemma":[0.00075418496,0.00043750933,0.00046157723,0.0027662867,0.000744919,0.0024296828,0.00076816336,0.0019245846,0.0020285908],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009751855,0.00015756319,0.00025007353,0.019030834,0.000066955094,0.00038168952,0.00019012493,0.0006937837,0.006678266,0.014764988,0.016935796,0.9407525],"study_design_scores_gemma":[0.000013442904,0.0001701336,0.00045280563,0.001743541,0.000053641983,0.0013264148,0.00009446713,0.000186985,0.0020329766,0.0032168557,0.9906853,0.000023421935],"about_ca_topic_score_codex":0.0005503167,"about_ca_topic_score_gemma":0.0009988905,"teacher_disagreement_score":0.0034827422,"about_ca_system_score_codex":0.0006940875,"about_ca_system_score_gemma":0.0008265085,"threshold_uncertainty_score":0.01165086},"labels":[],"label_agreement":null},{"id":"W2322941916","doi":"10.2174/156802612805219969","title":"Recent Developments in the Regulation of Monoamine Oxidase Form and Function: Is the Current Model Restricting Our Understanding of the Breadth of Contribution of Monoamine Oxidase to Brain [dys]Function?","year":2012,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Monoamine neurotransmitter; Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase A; Dopamine; Serotonin; Chemistry; Neuroscience; Biochemistry; Biology; Enzyme; Receptor","score_opus":0.13512804513257068,"score_gpt":0.35522062895266776,"score_spread":0.22009258382009708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2322941916","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0032878753,0.9672308,0.00619231,0.01919712,0.0014900627,0.000007251241,0.000045278313,0.00005030854,0.0024989743],"genre_scores_gemma":[0.028094126,0.9527635,0.0055059344,0.0063679987,0.005656331,0.000027371732,0.00009786063,0.000020896525,0.0014660049],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991283,0.00024426484,0.000111575544,0.00022779281,0.0001986187,0.00008944773],"domain_scores_gemma":[0.9958947,0.002000421,0.0005322291,0.00035746346,0.00092718616,0.00028803863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0046135713,0.0006764515,0.0013308953,0.0008058755,0.00054959813,0.0021825535,0.0017953756,0.0024263,0.0017030768],"category_scores_gemma":[0.0026950482,0.00036972866,0.00047821976,0.0012912878,0.0036341886,0.0063212374,0.0011508474,0.0048349546,0.0008347195],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00090008014,0.00026149722,0.0038174067,0.009924142,0.00017567164,0.0011879313,0.001005911,0.0016627364,0.041616496,0.12284586,0.02874328,0.78785896],"study_design_scores_gemma":[0.000034548713,0.0007781854,0.007168047,0.0021526066,0.00025421366,0.0037472567,0.0012424758,0.0019547408,0.015432778,0.10058283,0.86646247,0.00018981435],"about_ca_topic_score_codex":0.0013505624,"about_ca_topic_score_gemma":0.0016255017,"teacher_disagreement_score":0.0046135713,"about_ca_system_score_codex":0.0015757543,"about_ca_system_score_gemma":0.0016881797,"threshold_uncertainty_score":0.024399221},"labels":[],"label_agreement":null},{"id":"W2326057393","doi":"10.2174/15680266106061353","title":"Advances in the Development of Bradykinin Receptor Ligands","year":2006,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"","keywords":"Kinin; Receptor; Pharmacophore; Bradykinin; Pharmacology; Kallidin; G protein-coupled receptor; Computational biology; Chemistry; Neuroscience; Biology; Biochemistry","score_opus":0.05969561486092607,"score_gpt":0.38641576720500453,"score_spread":0.3267201523440785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2326057393","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00064931216,0.9949596,0.00093095447,0.00031189373,0.0002043238,0.000009293266,0.000011898858,0.0000174699,0.0029053222],"genre_scores_gemma":[0.0023913342,0.9949713,0.0010774451,0.00018258653,0.00022355956,0.000009353714,0.000020421196,0.0000019903473,0.0011220466],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997824,0.000033430308,0.000027416952,0.000041961477,0.00009549336,0.00001941833],"domain_scores_gemma":[0.9998099,0.00007669668,0.000028451343,0.000008762239,0.00005088318,0.000025250694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006107961,0.00066549395,0.00092065206,0.0015476613,0.0002851779,0.00070705154,0.0006054519,0.00085666066,0.0026128625],"category_scores_gemma":[0.00040628773,0.00025255873,0.00029134506,0.0015133511,0.00041094943,0.001407266,0.00055526313,0.0011401958,0.0023909973],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095884585,0.00018154668,0.00017450568,0.010006436,0.000044677563,0.0004642151,0.00012381955,0.0007708699,0.013413922,0.012575462,0.009804162,0.95234466],"study_design_scores_gemma":[0.00002807745,0.00023399806,0.0007126387,0.0009237454,0.000041166575,0.0012209002,0.000049740738,0.00022046789,0.0041351155,0.0028507872,0.98956573,0.000017562945],"about_ca_topic_score_codex":0.00046586388,"about_ca_topic_score_gemma":0.0006046333,"teacher_disagreement_score":0.0026128625,"about_ca_system_score_codex":0.00051559386,"about_ca_system_score_gemma":0.0007728861,"threshold_uncertainty_score":0.008740902},"labels":[],"label_agreement":null},{"id":"W2332498686","doi":"10.2174/156802611796391212","title":"Chemogenomic Approaches for the Exploration of GPCR Space","year":2011,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"G protein-coupled receptor; Pharmacophore; Context (archaeology); Computational biology; Computer science; Drug discovery; Functional selectivity; Ligand (biochemistry); Fingerprint (computing); Data science; Artificial intelligence; Bioinformatics; Receptor; Chemistry; Biology; Biochemistry","score_opus":0.35254726959959115,"score_gpt":0.40874298796560116,"score_spread":0.056195718366010006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2332498686","genre_codex":"methods","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0063176593,0.39122635,0.5817909,0.0015436357,0.00038001328,0.00019184318,0.00046811264,0.00087219325,0.017209303],"genre_scores_gemma":[0.0740454,0.49894,0.41862056,0.0010949072,0.0004598574,0.000677723,0.0008140412,0.00015057386,0.005196957],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997061,0.00007827812,0.000016905016,0.00006212562,0.00012024808,0.000016305812],"domain_scores_gemma":[0.9995301,0.00030613365,0.000036430956,0.000050051734,0.00006356581,0.000013757863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006594214,0.0008126751,0.0012898546,0.0018794324,0.0002224609,0.00094736496,0.0010047791,0.00086993043,0.0028707027],"category_scores_gemma":[0.00097424886,0.00037655566,0.0011672837,0.0022897457,0.00095505785,0.0011262444,0.00076733733,0.0014973639,0.0012972862],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007740479,0.00014584146,0.0009621178,0.0070895823,0.00026360922,0.00020443842,0.000093074355,0.031533476,0.021834675,0.12861119,0.0074047456,0.80177987],"study_design_scores_gemma":[0.000097127886,0.0006161328,0.0031453997,0.0015460061,0.00038423322,0.0029920563,0.00017120784,0.15303136,0.047985643,0.17938527,0.61038536,0.00026009782],"about_ca_topic_score_codex":0.00060601736,"about_ca_topic_score_gemma":0.00061939075,"teacher_disagreement_score":0.0028707027,"about_ca_system_score_codex":0.00069552934,"about_ca_system_score_gemma":0.0007628273,"threshold_uncertainty_score":0.0096035},"labels":[],"label_agreement":null},{"id":"W2333303354","doi":"10.2174/156802611797470376","title":"Thalamocortical Oscillations: Local Control of EEG Slow Waves","year":2011,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Neural dynamics and brain function","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of Neurological Disorders and Stroke; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Neocortex; Neuroscience; Electroencephalography; Reticular connective tissue; Thalamus; Oscillation (cell signaling); Reticular formation; Thalamic reticular nucleus; Mechanism (biology); Rhythm; Computer science; Nucleus; Physics; Biology; Anatomy","score_opus":0.07932839974948033,"score_gpt":0.3424429070872604,"score_spread":0.2631145073377801,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2333303354","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009368946,0.99078476,0.003427979,0.00027841987,0.0002526009,0.000012552678,0.000025844187,0.000053306892,0.0042276536],"genre_scores_gemma":[0.010919855,0.9850832,0.0013305104,0.00015396063,0.00056596263,0.000023307843,0.00005024417,0.000008763569,0.0018641953],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99991333,0.000013278792,0.000011110028,0.000023769911,0.000030185101,0.000008352232],"domain_scores_gemma":[0.9999001,0.000042317675,0.000017065617,0.0000053667036,0.000025947416,0.000009185468],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023777397,0.0007208618,0.000787332,0.0010840999,0.00019448258,0.0007260747,0.00068332226,0.00066644786,0.0017107634],"category_scores_gemma":[0.00030661703,0.00021398485,0.0002773635,0.00073869526,0.000644102,0.00087752094,0.00047342427,0.0008153073,0.0013126688],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007505242,0.00003352061,0.00033920188,0.007055538,0.0000617534,0.00038277265,0.00013908237,0.00062337477,0.018444479,0.011910707,0.006302299,0.9546321],"study_design_scores_gemma":[0.000040475476,0.00029254257,0.005058622,0.0022670308,0.00014758906,0.007679926,0.00018450232,0.0012163923,0.013331368,0.017148541,0.9525542,0.00007881165],"about_ca_topic_score_codex":0.00052358623,"about_ca_topic_score_gemma":0.00050460594,"teacher_disagreement_score":0.0017107634,"about_ca_system_score_codex":0.00037324565,"about_ca_system_score_gemma":0.00038656648,"threshold_uncertainty_score":0.005723119},"labels":[],"label_agreement":null},{"id":"W2336090556","doi":"10.2174/1568026616666160414124816","title":"Overview of the Genetic Basis and Epigenetic Mechanisms that Contribute to FASD Pathobiology","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Epigenetics; DNA methylation; Phenotype; Epigenome; Biology; Genetics; Histone; Bioinformatics; Gene; Gene expression","score_opus":0.05806341845818775,"score_gpt":0.350892113721131,"score_spread":0.29282869526294325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2336090556","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021541112,0.9876902,0.001900731,0.002232234,0.00035534127,0.00002101989,0.00022271443,0.000068443675,0.005355162],"genre_scores_gemma":[0.005338679,0.9889683,0.001801379,0.00075569167,0.0004639771,0.000024243727,0.00038598682,0.000005860451,0.0022558558],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999021,0.00001616702,0.000018315144,0.000026839512,0.000022043707,0.000014464284],"domain_scores_gemma":[0.9998455,0.000055855326,0.000033404176,0.0000055740247,0.000037018806,0.000022649912],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028681333,0.0006379818,0.00054379273,0.0015810491,0.00028776377,0.00073797547,0.00044209647,0.000722753,0.0038108246],"category_scores_gemma":[0.0002282186,0.0002645706,0.0005340625,0.00086054596,0.00030375458,0.00086954224,0.00041572415,0.001301318,0.0007880154],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032885044,0.00014717288,0.0034835855,0.015509075,0.00029506482,0.0012660486,0.0002402264,0.00085630507,0.029385664,0.0133264735,0.041464135,0.8936974],"study_design_scores_gemma":[0.0000265797,0.0003277724,0.010070167,0.0035890879,0.0005204229,0.0054794764,0.00019460697,0.00049970695,0.0045248275,0.009591812,0.9651236,0.000052090723],"about_ca_topic_score_codex":0.001730703,"about_ca_topic_score_gemma":0.002432818,"teacher_disagreement_score":0.0038108246,"about_ca_system_score_codex":0.0007166519,"about_ca_system_score_gemma":0.0010005073,"threshold_uncertainty_score":0.01274848},"labels":[],"label_agreement":null},{"id":"W2336363203","doi":"10.2174/1568026616666160413142028","title":"Function and Chemotypes of Human Hsp70 Chaperones","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Chaperone (clinical); Hsp70; Endoplasmic reticulum; Cell biology; Mitochondrion; Biology; Protein folding; Cytosol; Programmed cell death; Hsp90; Drug discovery; Heat shock protein; Cancer cell; Computational biology; Apoptosis; Cancer; Bioinformatics; Biochemistry; Medicine; Genetics; Enzyme","score_opus":0.07019045968782686,"score_gpt":0.3993152912579746,"score_spread":0.3291248315701477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2336363203","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021428638,0.9929034,0.0005551183,0.00018517315,0.00010505015,0.000010643913,0.0001571763,0.000028407112,0.003912243],"genre_scores_gemma":[0.012437477,0.9837209,0.0007731639,0.00019010564,0.00010083771,0.000019346775,0.0002267622,0.0000059942254,0.0025254318],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999081,0.000011782754,0.000010597691,0.000021813716,0.00003470411,0.000013052947],"domain_scores_gemma":[0.99993193,0.00001804102,0.000016524675,0.0000035635967,0.000019549641,0.000010333523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018272045,0.00056842016,0.0006063522,0.0015965491,0.00013672389,0.00043628656,0.00044233128,0.00032600504,0.0021682107],"category_scores_gemma":[0.00026506875,0.00015496317,0.00033716697,0.0016460104,0.00025794172,0.00052931445,0.0003938141,0.00074672996,0.0022481007],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016923204,0.00010221958,0.0005220245,0.011014682,0.00009557371,0.00022937809,0.0000701916,0.0011693855,0.026094286,0.006732642,0.015768874,0.93803144],"study_design_scores_gemma":[0.000025882526,0.00028237354,0.0026317257,0.0012097219,0.00010512647,0.0019864372,0.00004851021,0.00033700097,0.014015186,0.0027458542,0.9765767,0.000035451718],"about_ca_topic_score_codex":0.00053867756,"about_ca_topic_score_gemma":0.0006974875,"teacher_disagreement_score":0.0021682107,"about_ca_system_score_codex":0.0003167789,"about_ca_system_score_gemma":0.0003416898,"threshold_uncertainty_score":0.0072534084},"labels":[],"label_agreement":null},{"id":"W2339486157","doi":"10.2174/1568026616666160414124323","title":"Histone Variants and Composition in the Developing Brain: Should MeCP2 Care?","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Chromatin; Histone-modifying enzymes; Histone; Chromatin remodeling; Biology; Epigenetics; MECP2; Histone code; Genetics; Nucleosome; Cell biology; Neuroscience; Computational biology; DNA; Gene; Phenotype","score_opus":0.05270152571617083,"score_gpt":0.36707621355964526,"score_spread":0.31437468784347444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2339486157","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000163159,0.99849415,0.000090137444,0.00064710213,0.00013997874,0.0000013829242,0.0000109094035,0.0000041493086,0.000449022],"genre_scores_gemma":[0.0011235581,0.9976215,0.0001646287,0.00031541998,0.00020572938,0.0000026478147,0.000018799117,0.0000014900237,0.00054626574],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99990785,0.000016025473,0.000016489268,0.00001791775,0.000030524032,0.000011237048],"domain_scores_gemma":[0.999856,0.000056656623,0.000023538509,0.000004855468,0.00004077101,0.000018211835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046654444,0.00042633482,0.0008259786,0.0008533043,0.00014038169,0.0005939787,0.00061589025,0.0010002275,0.0015943432],"category_scores_gemma":[0.0006008089,0.00016283125,0.00025231348,0.00080026087,0.00052665226,0.0012004114,0.00043588955,0.0011368153,0.0010493362],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010095349,0.000023481221,0.0004693388,0.007847004,0.000069396025,0.00029740948,0.00008799065,0.0002455205,0.0033026943,0.0040113754,0.023112755,0.9604321],"study_design_scores_gemma":[0.000023595063,0.00008678819,0.0029948854,0.0023628676,0.000113343835,0.0032720598,0.00014885927,0.00011691019,0.0012685393,0.00430913,0.98527735,0.000025758389],"about_ca_topic_score_codex":0.0014373467,"about_ca_topic_score_gemma":0.0022739246,"teacher_disagreement_score":0.0015943432,"about_ca_system_score_codex":0.00056565215,"about_ca_system_score_gemma":0.00074574427,"threshold_uncertainty_score":0.0053336024},"labels":[],"label_agreement":null},{"id":"W2342247785","doi":"10.2174/1568026615666150915112459","title":"Short Antimicrobial Peptides and Peptide Scaffolds as Promising Antibacterial Agents","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Antimicrobial; Antimicrobial peptides; Peptidomimetic; Antibiotics; Peptide; Bacteria; Combinatorial chemistry; Chemistry; Biology; Computational biology; Microbiology; Biochemistry","score_opus":0.04021102440206558,"score_gpt":0.33296880698443937,"score_spread":0.2927577825823738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2342247785","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013675361,0.9958574,0.00045600822,0.00014490132,0.00016426913,0.00000785411,0.000024090876,0.000012391084,0.001965533],"genre_scores_gemma":[0.0064877938,0.99096876,0.0006949837,0.00015081787,0.00019749606,0.000013048907,0.00003833422,0.0000025608515,0.0014462956],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99988496,0.000018838302,0.00001101317,0.000021427935,0.00004576121,0.000017961],"domain_scores_gemma":[0.99993587,0.000020000505,0.000015660818,0.0000024054948,0.000013774951,0.000012290243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027635807,0.0006276063,0.0006750295,0.0010675178,0.0001881446,0.0006557066,0.00042085917,0.00075033685,0.0023371608],"category_scores_gemma":[0.0002242194,0.00021379844,0.00024804723,0.0009202513,0.000338957,0.0010434074,0.00048231866,0.0009975102,0.0015487279],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013578385,0.000173881,0.0002701734,0.016385732,0.00005863697,0.0005801375,0.00013853247,0.0009589178,0.06157836,0.012563698,0.01299263,0.89416355],"study_design_scores_gemma":[0.000024226676,0.00036073363,0.00084138825,0.0014098585,0.00006241439,0.0020148372,0.000075509175,0.00028541524,0.011811532,0.0028350705,0.9802491,0.000030058569],"about_ca_topic_score_codex":0.00015696575,"about_ca_topic_score_gemma":0.00035068655,"teacher_disagreement_score":0.0023371608,"about_ca_system_score_codex":0.00023473061,"about_ca_system_score_gemma":0.00031147373,"threshold_uncertainty_score":0.00781858},"labels":[],"label_agreement":null},{"id":"W2402298570","doi":"10.2174/1568026615666150701115012","title":"Nuclear Targeting of Gold Nanoparticles for Improved Therapeutics","year":2015,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Nanomedicine; Colloidal gold; Cancer therapy; Nanotechnology; Cancer; Cancer research; DNA damage; Cytoplasm; Radiation therapy; Nucleus; Cancer cell; Chemistry; Nanoparticle; Computational biology; Medicine; DNA; Biology; Cell biology; Materials science; Biochemistry; Internal medicine","score_opus":0.07793156887213819,"score_gpt":0.3575811981921471,"score_spread":0.2796496293200089,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2402298570","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021082505,0.9897738,0.0026710627,0.00035487604,0.0003016356,0.000017155242,0.000020497253,0.00003377657,0.0047189477],"genre_scores_gemma":[0.018771078,0.97238433,0.002928637,0.00037830567,0.00021114518,0.00003464617,0.000055032993,0.00001062096,0.005226185],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998808,0.000020158723,0.0000095798905,0.000024276393,0.000046954854,0.00001822822],"domain_scores_gemma":[0.9999548,0.000013891835,0.000008369507,0.0000027432104,0.000015469022,0.000004679143],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027752752,0.0006157104,0.0006694079,0.0010070523,0.00019149302,0.0005317899,0.00043867488,0.00093667355,0.001439496],"category_scores_gemma":[0.00016822376,0.00026953054,0.00039954396,0.00058742595,0.00033157595,0.00072060624,0.0005328889,0.0008998755,0.0013010913],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009374312,0.00014131023,0.00018058329,0.019369094,0.00010109316,0.0009417326,0.00023964752,0.0015046498,0.17460604,0.02508917,0.021876466,0.75585645],"study_design_scores_gemma":[0.000018057737,0.00020330423,0.00046680908,0.00088358345,0.000068126836,0.0020403524,0.00005753462,0.0007940637,0.047493745,0.0032310092,0.9447118,0.00003159231],"about_ca_topic_score_codex":0.0005527723,"about_ca_topic_score_gemma":0.00081519043,"teacher_disagreement_score":0.001439496,"about_ca_system_score_codex":0.0004857231,"about_ca_system_score_gemma":0.00043078224,"threshold_uncertainty_score":0.004815519},"labels":[],"label_agreement":null},{"id":"W2418559502","doi":"10.2174/1568026616666160530154649","title":"The Impending Renaissance in Discovery & Development of Natural Products","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Drug discovery; Metagenomics; Biochemical engineering; Antimicrobial; Biotechnology; Data science; Risk analysis (engineering); Drug development; Computer science; Business; Engineering; Biology; Drug; Bioinformatics","score_opus":0.05967249200745428,"score_gpt":0.3610915688211706,"score_spread":0.3014190768137163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2418559502","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002515428,0.9923455,0.00062771735,0.0022595553,0.0008930716,0.0000054735838,0.000019461844,0.00002540914,0.0035723087],"genre_scores_gemma":[0.0018714323,0.9926131,0.000879634,0.0011770765,0.0006436657,0.000007980391,0.000028040526,0.0000073515935,0.0027717387],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99934953,0.00011513009,0.000059382077,0.000106901294,0.00030303132,0.000065997796],"domain_scores_gemma":[0.9990965,0.00036596728,0.00011687729,0.000053639997,0.00022356308,0.00014347362],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013035528,0.0007641813,0.001033494,0.0021599797,0.0004747769,0.0019504256,0.0008251428,0.002104392,0.0042493236],"category_scores_gemma":[0.0012075205,0.00029476907,0.00054018945,0.002882632,0.0017652106,0.003961892,0.0011386886,0.0033013804,0.0034455177],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007519397,0.00010413975,0.00020721034,0.009453433,0.00004610683,0.00033057737,0.00016550637,0.0004009781,0.005659038,0.04362197,0.060818173,0.8791177],"study_design_scores_gemma":[0.000006028579,0.000057699246,0.00026753062,0.00086739997,0.000013552071,0.0006210689,0.000060442173,0.000085525215,0.0007185683,0.005117382,0.9921744,0.000010393926],"about_ca_topic_score_codex":0.00067846745,"about_ca_topic_score_gemma":0.0011914496,"teacher_disagreement_score":0.0042493236,"about_ca_system_score_codex":0.0011354646,"about_ca_system_score_gemma":0.0020435746,"threshold_uncertainty_score":0.01421541},"labels":[],"label_agreement":null},{"id":"W2514026372","doi":"10.2174/1568026616666160824104052","title":"Heterocyclic Amaryllidaceae Alkaloids: Biosynthesis and Pharmacological Applications","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Chemical synthesis and alkaloids","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"","keywords":"Amaryllidaceae Alkaloids; Amaryllidaceae; Biosynthesis; Chemistry; Traditional medicine; Biology; Botany; Biochemistry; Medicine; Gene","score_opus":0.0473759608073837,"score_gpt":0.3552078843769329,"score_spread":0.3078319235695492,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2514026372","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017881285,0.9903916,0.0005701113,0.00020331184,0.000142272,0.000016074988,0.000119957884,0.000029130591,0.006739371],"genre_scores_gemma":[0.010418525,0.9831717,0.00099852,0.00018102633,0.00014987071,0.000014702207,0.00020640013,0.0000072361313,0.0048520504],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999243,0.000007328963,0.000008798833,0.000017406759,0.000031627937,0.000010573533],"domain_scores_gemma":[0.9999311,0.000016672191,0.000015257735,0.0000031047318,0.000023026765,0.000010870778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014820107,0.0005099533,0.00056095264,0.0013359942,0.0002558261,0.00058301835,0.00039920778,0.00051619206,0.0052069887],"category_scores_gemma":[0.00017940237,0.00021020113,0.0002921333,0.0010758636,0.00018455637,0.00070384296,0.0004128896,0.0007850451,0.0032397597],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013519995,0.00013799571,0.00030676625,0.01994269,0.000073858566,0.000497168,0.000109854955,0.00062069,0.057855062,0.0049116737,0.013154703,0.9022543],"study_design_scores_gemma":[0.000015662092,0.00019034279,0.0013431306,0.0011203819,0.000074894946,0.0016762471,0.00004908635,0.00021430838,0.0101154,0.0014611455,0.98371834,0.000021082966],"about_ca_topic_score_codex":0.0005419886,"about_ca_topic_score_gemma":0.0013429781,"teacher_disagreement_score":0.0052069887,"about_ca_system_score_codex":0.00032758212,"about_ca_system_score_gemma":0.00046473747,"threshold_uncertainty_score":0.01741916},"labels":[],"label_agreement":null},{"id":"W2558057290","doi":"10.2174/1568026617666161116143440","title":"Bioinformatics and Drug Discovery","year":2017,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Genetics, Bioinformatics, and Biomedical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":245,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Drug discovery; Computational biology; Drug repositioning; Computer science; Profiling (computer programming); Proteomics; Structural genomics; Identification (biology); Virtual screening; Drug; Bioinformatics; Data science; Biology; Protein structure; Gene; Pharmacology; Genetics","score_opus":0.06991515649462367,"score_gpt":0.3936113403846406,"score_spread":0.3236961838900169,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2558057290","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00031771426,0.93813187,0.011463496,0.016934147,0.0033446527,0.00013256907,0.00042777983,0.00032811594,0.02891978],"genre_scores_gemma":[0.0038564536,0.9659312,0.009088724,0.008586979,0.0026079305,0.00014608243,0.00062943436,0.000063964624,0.00908926],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977259,0.00066716276,0.00019021954,0.00029930988,0.0009806807,0.0001368435],"domain_scores_gemma":[0.9975107,0.0013902609,0.000159571,0.00020684258,0.00052238,0.00021019106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0031698036,0.0015533603,0.0022081987,0.0033547143,0.0006013302,0.0047693183,0.0032277082,0.0028705415,0.014940319],"category_scores_gemma":[0.005040191,0.000562844,0.0010513098,0.004956605,0.0025229417,0.0045174393,0.0024807788,0.0060376213,0.014807465],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004252977,0.00007858522,0.0002746334,0.0058163046,0.0001530573,0.00018446836,0.00009364623,0.0011711145,0.0006214489,0.074124955,0.14792372,0.7695157],"study_design_scores_gemma":[0.000014301481,0.000031206517,0.00014705874,0.0012262397,0.000021898268,0.00034660322,0.000031827778,0.0002487976,0.00017826009,0.024894487,0.972845,0.000014417251],"about_ca_topic_score_codex":0.001679798,"about_ca_topic_score_gemma":0.0015923823,"teacher_disagreement_score":0.014940319,"about_ca_system_score_codex":0.0026033067,"about_ca_system_score_gemma":0.0039427653,"threshold_uncertainty_score":0.049980342},"labels":[],"label_agreement":null},{"id":"W2581688433","doi":"10.2174/1568026616999160812144822","title":"Editorial (Thematic Issue: NeuroEpigenetics and Neurodevelopmental Disorders: From Molecular Mechanisms to Cell Fate Commitments of the Brain Cells and Human Disease)","year":2017,"lang":"en","type":"editorial","venue":"Current Topics in Medicinal Chemistry","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Disease; Neuroscience; Brain Cell; Thematic map; Brain disease; Cell; Medicine; Psychology; Biology; Pathology; Genetics; Geography","score_opus":0.00689844275887109,"score_gpt":0.26286011989800406,"score_spread":0.255961677139133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2581688433","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003141711,0.0036812872,0.00008141567,0.019640593,0.97513586,0.0000172143,0.000048835034,0.000025616842,0.0013378471],"genre_scores_gemma":[0.00027068448,0.0032370596,0.00007342017,0.011644216,0.9773029,0.000019901781,0.000036008372,0.00002053933,0.007395425],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99725336,0.00049072475,0.00030799047,0.00036182825,0.0013306312,0.00025538568],"domain_scores_gemma":[0.99123454,0.0030652077,0.0008745707,0.00020555528,0.0027807744,0.0018394113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005185591,0.003135572,0.0027254054,0.0028864148,0.0024683913,0.00618717,0.002673194,0.010108425,0.021632453],"category_scores_gemma":[0.012212008,0.00081820023,0.0022818,0.0012699323,0.001880464,0.0033709258,0.0018440745,0.013430188,0.011594203],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046367528,0.0000137352,0.000020521145,0.00019560127,0.000015040276,0.000092150956,0.000007431664,0.000023202092,0.00009283094,0.00026809314,0.9945621,0.004662943],"study_design_scores_gemma":[0.00009165324,0.000040181338,0.00031907615,0.00045790407,0.000058779646,0.00022819116,0.000034334094,0.00014191661,0.00018556304,0.0013945608,0.99702954,0.000018186141],"about_ca_topic_score_codex":0.0009689396,"about_ca_topic_score_gemma":0.0032164783,"teacher_disagreement_score":0.021632453,"about_ca_system_score_codex":0.0023824242,"about_ca_system_score_gemma":0.003245817,"threshold_uncertainty_score":0.07236779},"labels":[],"label_agreement":null},{"id":"W2586156640","doi":"10.2174/1568026617666170104143618","title":"Novel Colchicine Derivatives and their Anti-cancer Activity","year":2017,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Pharmacophore; Colchicine; Tubulin; Cancer; Cancer cell lines; Cancer cell; Computational biology; Chemistry; Cancer research; Biology; Biochemistry; Pharmacology; Microtubule; Cell biology; Genetics","score_opus":0.23062233847538824,"score_gpt":0.4199642387482792,"score_spread":0.18934190027289097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586156640","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001924974,0.99145526,0.0006325488,0.00019359945,0.0002250454,0.00001879058,0.000101789214,0.000030143176,0.0054178145],"genre_scores_gemma":[0.010792208,0.9843536,0.0007321116,0.00021814085,0.00014916442,0.000020412397,0.0001481385,0.000005567367,0.0035807865],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99993193,0.000008122106,0.0000067799474,0.000014599032,0.000027416032,0.000011157614],"domain_scores_gemma":[0.99995077,0.00001548171,0.000009873685,0.0000021104993,0.000014197294,0.0000075849357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012733835,0.00062150176,0.00049293897,0.0013478898,0.00020277842,0.0004756779,0.00036230672,0.0005010883,0.0043060435],"category_scores_gemma":[0.00018003932,0.00018725956,0.00024481706,0.0010265533,0.00021235438,0.0004942839,0.00032245833,0.0009315099,0.0017188436],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014062984,0.0001499636,0.00018603333,0.01952063,0.00007573868,0.00048937777,0.00007773023,0.0011890355,0.052679934,0.006614367,0.017360207,0.9015164],"study_design_scores_gemma":[0.00002082771,0.00033544024,0.00088439806,0.00092545094,0.0000887826,0.0015998587,0.000041851108,0.00024821196,0.018693496,0.0009983834,0.97613394,0.000029452729],"about_ca_topic_score_codex":0.00076593395,"about_ca_topic_score_gemma":0.0018761747,"teacher_disagreement_score":0.0043060435,"about_ca_system_score_codex":0.00038350068,"about_ca_system_score_gemma":0.0003137214,"threshold_uncertainty_score":0.014405191},"labels":[],"label_agreement":null},{"id":"W2609415147","doi":"10.2174/1568026617666170414143430","title":"Computational Models for Understanding of Structure, Function and Pharmacology of the Cardiac Potassium Channel Kv11.1 (hERG)","year":2017,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"hERG; Potassium channel; Potassium channel blocker; Pharmacology; Potassium channel opener; Channel (broadcasting); Function (biology); Chemistry; Computational biology; Medicine; Computer science; Cell biology; Biology; Internal medicine; Computer network","score_opus":0.1133421972491916,"score_gpt":0.384967642041575,"score_spread":0.27162544479238343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2609415147","genre_codex":"methods","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11664378,0.0329546,0.7393028,0.010258183,0.001163544,0.00036337526,0.011712119,0.0021353145,0.08546626],"genre_scores_gemma":[0.69667643,0.027337993,0.24062148,0.0017059929,0.0007812565,0.002393348,0.010728266,0.0010875476,0.01866767],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9997781,0.00009353608,0.000013359885,0.000030385896,0.000057608817,0.00002711355],"domain_scores_gemma":[0.9992478,0.0005642361,0.00003623448,0.000037181453,0.00007132847,0.000043246855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004765547,0.0011223413,0.0014896826,0.00046365513,0.00068360753,0.0014485153,0.0020693748,0.0021312188,0.0062342305],"category_scores_gemma":[0.0021559473,0.00059088354,0.0013738385,0.0009031658,0.00061890215,0.0014113683,0.001104536,0.0018094736,0.0010170465],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004155645,0.00003269742,0.00057559565,0.00029980857,0.00006847875,0.000095603405,0.00004796406,0.9599884,0.00037592568,0.028454242,0.0030533045,0.0069664153],"study_design_scores_gemma":[0.00003156556,0.000021121032,0.00014712935,0.000066408735,0.00002587514,0.000034370783,0.000034053028,0.95705414,0.00015542387,0.03540341,0.007015545,0.000011052489],"about_ca_topic_score_codex":0.008574741,"about_ca_topic_score_gemma":0.0075342157,"teacher_disagreement_score":0.008574741,"about_ca_system_score_codex":0.0008545072,"about_ca_system_score_gemma":0.0017514895,"threshold_uncertainty_score":0.020855546},"labels":[],"label_agreement":null},{"id":"W2890191325","doi":"10.2174/1568026618666181115093136","title":"Anxiety Disorders: Sex Differences in Serotonin and Tryptophan Metabolism","year":2018,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Serotonin transporter; Anxiety; Serotonin; Anxiogenic; Kynurenine; Serotonin Plasma Membrane Transport Proteins; Medicine; Endocrinology; Internal medicine; Psychology; Tryptophan; Biology; Psychiatry; Receptor; Anxiolytic; Genetics","score_opus":0.06359803012698073,"score_gpt":0.3413592930979954,"score_spread":0.27776126297101467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890191325","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016774402,0.996816,0.00006709968,0.00044057684,0.00011241949,0.00000768678,0.00016278817,0.000003649958,0.0007123894],"genre_scores_gemma":[0.016237678,0.9824598,0.0001584088,0.0003585927,0.00022475689,0.00001723804,0.0001413315,0.0000015881812,0.00040069042],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99975866,0.00006838754,0.00005155354,0.00004587957,0.000053082036,0.000022393504],"domain_scores_gemma":[0.9995061,0.00027497046,0.00015036475,0.0000064794385,0.00004878827,0.000013374503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035532832,0.0003307447,0.00087934226,0.0011128548,0.00016844239,0.00089794147,0.00025330123,0.00046910637,0.0044028526],"category_scores_gemma":[0.0010368332,0.00012172875,0.0006767903,0.0014971622,0.00025942302,0.00055272545,0.0003819721,0.00034116214,0.00043836434],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006185852,0.000041983698,0.00821568,0.14701179,0.0011991935,0.0013003941,0.00060933456,0.000197429,0.0027998276,0.003119821,0.017503306,0.8173827],"study_design_scores_gemma":[0.00017389748,0.0008875778,0.1032349,0.12271234,0.007186041,0.02108653,0.0017473577,0.00020800065,0.0024004318,0.0062689455,0.73396647,0.00012750877],"about_ca_topic_score_codex":0.0021736966,"about_ca_topic_score_gemma":0.0024802384,"teacher_disagreement_score":0.0044028526,"about_ca_system_score_codex":0.00038082802,"about_ca_system_score_gemma":0.00091919984,"threshold_uncertainty_score":0.014728963},"labels":[],"label_agreement":null},{"id":"W2901198337","doi":"10.2174/1568026618666181115101625","title":"Common Environmental Factors May Underpin the Comorbidity Between Generalized Anxiety Disorder and Mood Disorders Via Activated Nitrooxidative Pathways","year":2018,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Comorbidity; Bipolar disorder; Generalized anxiety disorder; Mood disorders; Major depressive disorder; Mood; Anxiety; Psychology; Depression (economics); Clinical psychology; Psychiatry; Medicine","score_opus":0.07303532240738458,"score_gpt":0.330020257336779,"score_spread":0.2569849349293944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901198337","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0111833485,0.98390305,0.000560515,0.0014410022,0.00027092846,0.00004576839,0.00043926068,0.000014826787,0.0021412808],"genre_scores_gemma":[0.0990633,0.8962066,0.0013377866,0.001448085,0.00050358445,0.00007861978,0.00057249767,0.0000073378437,0.00078209117],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994124,0.00016074452,0.00017510446,0.00008893925,0.00011823825,0.00004454758],"domain_scores_gemma":[0.9985097,0.00083189167,0.00046251324,0.00002843397,0.0001320195,0.000035435747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062562805,0.0004029254,0.00097415055,0.0017799947,0.0002777488,0.0011215642,0.0003555886,0.0005631727,0.0022049095],"category_scores_gemma":[0.0029939446,0.00020276857,0.0013449308,0.0021219936,0.0003530695,0.00077340705,0.0006546495,0.0005763997,0.000213335],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068065326,0.0001292674,0.07370138,0.20376316,0.0073487787,0.01290618,0.0023437494,0.0008074222,0.00358497,0.0117097525,0.022992617,0.660032],"study_design_scores_gemma":[0.0002768328,0.0005962665,0.29396734,0.1210346,0.016107567,0.06808561,0.004853834,0.00080775045,0.0017267757,0.021272082,0.47103095,0.00024035417],"about_ca_topic_score_codex":0.002931829,"about_ca_topic_score_gemma":0.0058012945,"teacher_disagreement_score":0.002931829,"about_ca_system_score_codex":0.0005571075,"about_ca_system_score_gemma":0.0015875772,"threshold_uncertainty_score":0.0073761344},"labels":[],"label_agreement":null},{"id":"W2901592444","doi":"10.2174/1568026618666181115100610","title":"Recognizing the Leaky Gut as a Trans-diagnostic Target for Neuroimmune Disorders Using Clinical Chemistry and Molecular Immunology Assays","year":2018,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Intestinal permeability; Dysbiosis; Immunology; Gut flora; Irritable bowel syndrome; Medicine; Microbiology; Biology; Internal medicine","score_opus":0.06746993243660257,"score_gpt":0.41109135792804896,"score_spread":0.34362142549144636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901592444","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007316454,0.98414004,0.0015269798,0.0016128967,0.0003562043,0.000119343895,0.0008624853,0.000046475947,0.004019133],"genre_scores_gemma":[0.06295309,0.9228294,0.007758258,0.0027316764,0.0008378526,0.0002232771,0.0011918626,0.000015866673,0.0014586804],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9985783,0.0004073779,0.00040566837,0.00016700914,0.00037268957,0.00006892992],"domain_scores_gemma":[0.9969806,0.0016414401,0.0007835355,0.00005581641,0.00047511657,0.00006333689],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001993334,0.0005628885,0.0018102429,0.007523345,0.00019300896,0.0015283542,0.0004871587,0.0009187926,0.0029300652],"category_scores_gemma":[0.0037166062,0.00017933566,0.0010284769,0.0057075657,0.0005162413,0.0013868872,0.00056060334,0.0005232176,0.00072366104],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008856229,0.00019652552,0.054352507,0.1743846,0.0015850189,0.0036941885,0.00044394998,0.0003115584,0.013843917,0.003964528,0.022987291,0.7233503],"study_design_scores_gemma":[0.0003516459,0.0017888095,0.18490928,0.08388276,0.0067864032,0.027230717,0.0022025083,0.00081565825,0.019814,0.008864789,0.6630234,0.00033004952],"about_ca_topic_score_codex":0.0009022209,"about_ca_topic_score_gemma":0.0016601803,"teacher_disagreement_score":0.007523345,"about_ca_system_score_codex":0.0005326647,"about_ca_system_score_gemma":0.0015021855,"threshold_uncertainty_score":0.010541856},"labels":[],"label_agreement":null},{"id":"W2912582226","doi":"10.2174/1568026619666190125145110","title":"Research Advances in the Use of Histone Deacetylase Inhibitors for Epigenetic Targeting of Cancer","year":2019,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Scientific Research Funds of Jilin Province of Health and Family Planning Commission; Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province; Department of Science and Technology of Jilin Province; Education Department of Jilin Province","keywords":"Epigenetics; Histone deacetylase; Histone; Epigenetic therapy; Cancer; Cancer epigenetics; Chromatin remodeling; Cancer research; Bioinformatics; Chromatin; Vorinostat; Medicine; Computational biology; Biology; DNA methylation; Gene expression; Gene; Genetics; Histone methyltransferase","score_opus":0.1787180327933119,"score_gpt":0.5138313555563935,"score_spread":0.3351133227630816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912582226","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00037317027,0.99635446,0.00048637984,0.0002806542,0.00020352547,0.000009923633,0.000029449422,0.000015785721,0.002246629],"genre_scores_gemma":[0.0015628297,0.997026,0.00038687803,0.00015700204,0.0001248389,0.000007258475,0.00003975964,0.000002365037,0.0006930572],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99983203,0.000026153733,0.000018665345,0.00003766565,0.00006666887,0.000018727646],"domain_scores_gemma":[0.99976355,0.00010953175,0.000031999458,0.000011717608,0.00005740917,0.000025794441],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005430477,0.000729721,0.00087243825,0.0022056794,0.00027188644,0.00065046333,0.0006266931,0.00067262043,0.0048487997],"category_scores_gemma":[0.000489598,0.00027164962,0.0005915276,0.0016795923,0.00040567317,0.0010455442,0.0006149386,0.0017693014,0.002279902],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009806224,0.00013847706,0.00018799645,0.015154979,0.0001020254,0.00026221303,0.000071199,0.00059153396,0.010081898,0.0071394173,0.017781012,0.94839126],"study_design_scores_gemma":[0.000031120504,0.00023514986,0.0008180003,0.0013619337,0.00014408528,0.0012868134,0.000037159094,0.00018887453,0.0033880766,0.0023824074,0.9901025,0.000023811499],"about_ca_topic_score_codex":0.00056319655,"about_ca_topic_score_gemma":0.0012026357,"teacher_disagreement_score":0.0048487997,"about_ca_system_score_codex":0.00046599488,"about_ca_system_score_gemma":0.0007285852,"threshold_uncertainty_score":0.016220868},"labels":[],"label_agreement":null},{"id":"W2956753841","doi":"10.2174/1568026619666190709092647","title":"Targeting the PAC1 Receptor for Neurological and Metabolic Disorders","year":2019,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Army Research Office; National Institute of General Medical Sciences; National Institutes of Health","keywords":"G protein-coupled receptor; Signal transduction; Neuroscience; Neurodegeneration; Nervous system; Receptor; Adenylyl cyclase; Cell biology; Biology; Medicine; Internal medicine; Disease","score_opus":0.10052878575586716,"score_gpt":0.36794677622102473,"score_spread":0.2674179904651576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2956753841","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006548455,0.97708637,0.0042236843,0.0013572441,0.0007118724,0.00006711881,0.00022145627,0.00012935848,0.009654413],"genre_scores_gemma":[0.028024917,0.95515364,0.0040765125,0.0013697091,0.0007045322,0.0001121765,0.00058715214,0.000021878373,0.009949426],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99990976,0.000012039462,0.000010547998,0.000016551972,0.000032010852,0.000019031011],"domain_scores_gemma":[0.9999651,0.0000071336485,0.000009815083,0.0000014395388,0.000009918977,0.000006711113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015487437,0.00053557096,0.00046129574,0.00047186363,0.0001631472,0.00053308933,0.00039771647,0.00056372315,0.0032390624],"category_scores_gemma":[0.00016630307,0.00011027649,0.00033774157,0.00031029203,0.00016522607,0.00049251463,0.00034885693,0.0011726817,0.0020860934],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003248985,0.00016643846,0.00037308616,0.0075787124,0.000099237666,0.0017529943,0.00013323702,0.00055008015,0.25175336,0.009910697,0.034435105,0.69292223],"study_design_scores_gemma":[0.00006401561,0.00043946356,0.0014962956,0.00050461467,0.0001277225,0.006096249,0.00005097611,0.0005605856,0.033706803,0.0018206756,0.9550934,0.000039177397],"about_ca_topic_score_codex":0.00030023942,"about_ca_topic_score_gemma":0.00051392097,"teacher_disagreement_score":0.0032390624,"about_ca_system_score_codex":0.0003250907,"about_ca_system_score_gemma":0.000307849,"threshold_uncertainty_score":0.010835767},"labels":[],"label_agreement":null},{"id":"W3003427449","doi":"10.2174/1568026620666200131125110","title":"Non-canonical Functions of Telomerase Reverse Transcriptase: Emerging Roles and Biological Relevance","year":2020,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Cancer Research Society","keywords":"Telomerase; Telomere; Telomerase reverse transcriptase; Biology; Cell biology; DNA damage; Reverse transcriptase; Mitochondrion; Telomerase RNA component; Chromatin; Mitochondrial DNA; RNA; Context (archaeology); Genetics; Gene; DNA","score_opus":0.06786236549586322,"score_gpt":0.3595202504898239,"score_spread":0.29165788499396067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003427449","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009910936,0.98431313,0.0022454245,0.0016905066,0.00018144783,0.0000040468435,0.00006769788,0.000027577307,0.0015592483],"genre_scores_gemma":[0.07745986,0.91653794,0.0025181917,0.0009090666,0.0011220647,0.000020363805,0.0002483319,0.000011645638,0.0011725476],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997094,0.00003655492,0.00003061353,0.00009559701,0.00008022661,0.00004754874],"domain_scores_gemma":[0.999209,0.00028837833,0.00018499736,0.000044546538,0.00017326286,0.00009979555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080789806,0.0005513426,0.0008114142,0.00071838434,0.00025205547,0.0017643605,0.0007791701,0.0010674049,0.0009228086],"category_scores_gemma":[0.0005745778,0.0002568624,0.00030704736,0.00088851363,0.0011888252,0.0020911728,0.0006345934,0.0017290531,0.00054618146],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054076343,0.00014409794,0.00826391,0.011973969,0.00012510923,0.0026950054,0.000676209,0.0014902875,0.18297517,0.050161935,0.009095053,0.73185855],"study_design_scores_gemma":[0.000064963446,0.00068836083,0.031823415,0.0018114761,0.000329212,0.011818477,0.001671808,0.005115078,0.052525647,0.10470239,0.78927296,0.0001762696],"about_ca_topic_score_codex":0.0003585021,"about_ca_topic_score_gemma":0.0005784922,"teacher_disagreement_score":0.0017643605,"about_ca_system_score_codex":0.0006309992,"about_ca_system_score_gemma":0.000727628,"threshold_uncertainty_score":0.0045782924},"labels":[],"label_agreement":null},{"id":"W3018703129","doi":"10.2174/1568026620666200423094423","title":"Ketamine Treatment in Depression: A Systematic Review of Clinical Characteristics Predicting Symptom Improvement","year":2020,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Treatment of Major Depression","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Ketamine; Antidepressant; Depression (economics); Context (archaeology); Medicine; Randomized controlled trial; Population; Psychiatry; Clinical psychology; Major depressive disorder; Clinical trial; Treatment-resistant depression; Psychology; Intensive care medicine; Internal medicine; Cognition","score_opus":0.08909335224496698,"score_gpt":0.44144513995378043,"score_spread":0.3523517877088135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3018703129","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00044265023,0.9988973,0.000060952676,0.000101132835,0.00004505711,0.0000661866,0.0002679944,0.0000050589183,0.00011354503],"genre_scores_gemma":[0.004337875,0.9948961,0.0002545394,0.00015913499,0.00003172082,0.000098694836,0.00017139628,0.0000025611969,0.00004795414],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9969408,0.00085076236,0.0012875232,0.00031175572,0.00052813045,0.00008094124],"domain_scores_gemma":[0.9822567,0.01328758,0.0029055974,0.000189628,0.0011624197,0.0001980717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0037852756,0.0012628506,0.006250863,0.006903446,0.00039679263,0.0015499406,0.0013913296,0.0010792115,0.0042249784],"category_scores_gemma":[0.022749312,0.00066013,0.0059399796,0.00949558,0.00064643583,0.0012768522,0.0009827352,0.0008548944,0.00038333927],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003201962,0.00002405056,0.0013026744,0.8709811,0.007097417,0.00007740359,0.00010174741,0.00011723728,0.00012348147,0.00018930838,0.0028413353,0.11682411],"study_design_scores_gemma":[0.0004304418,0.00037443393,0.015216642,0.8496557,0.09511856,0.0007502021,0.00023951069,0.00017027672,0.00024149995,0.0004671818,0.037269037,0.0000665269],"about_ca_topic_score_codex":0.0075182337,"about_ca_topic_score_gemma":0.022285692,"teacher_disagreement_score":0.0075182337,"about_ca_system_score_codex":0.0017853047,"about_ca_system_score_gemma":0.0063313064,"threshold_uncertainty_score":0.020018697},"labels":[],"label_agreement":null},{"id":"W3040005313","doi":"10.2174/1568026620666200628023540","title":"Application of a Novel Metallomics Tool to Probe the Fate of Metal-Based Anticancer Drugs in Blood Plasma: Potential, Challenges and Prospects","year":2020,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Alberta Innovates - Technology Futures","keywords":"Chemistry; Bioinorganic chemistry; Nanotechnology; Biochemistry; Materials science","score_opus":0.08414096269094812,"score_gpt":0.3328788513928159,"score_spread":0.2487378887018678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3040005313","genre_codex":"methods","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.44277525,0.038067468,0.5015972,0.007175967,0.0004875736,0.00035036384,0.001154446,0.0027341635,0.005657506],"genre_scores_gemma":[0.6759168,0.0226261,0.29248312,0.0014939619,0.00024961488,0.00033180366,0.0006652012,0.00020980688,0.006023564],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997459,0.000063789244,0.000012680556,0.000081239144,0.00006800407,0.00002835234],"domain_scores_gemma":[0.9997826,0.000078141646,0.000030783467,0.000028088796,0.00005196512,0.000028388286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00090475916,0.0006213884,0.00047727936,0.0003585021,0.00020691985,0.00079149194,0.0005586122,0.0010589871,0.00073813763],"category_scores_gemma":[0.00041291205,0.0002807881,0.00035474665,0.00028469623,0.00057296286,0.0008008215,0.0004327323,0.0008231484,0.00043578155],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007138355,0.000027467842,0.00035074275,0.00012168322,0.000012313948,0.00011422036,0.000028357337,0.00015408835,0.99026895,0.00037279906,0.0002527638,0.008225173],"study_design_scores_gemma":[0.0000124199305,0.00020351696,0.0013937828,0.00001384422,0.000024153684,0.00058482034,0.000051437906,0.004944913,0.9848424,0.0004677931,0.0074362806,0.00002459367],"about_ca_topic_score_codex":0.00034191512,"about_ca_topic_score_gemma":0.00045800433,"teacher_disagreement_score":0.0010589871,"about_ca_system_score_codex":0.00030564368,"about_ca_system_score_gemma":0.00031006994,"threshold_uncertainty_score":0.004784882},"labels":[],"label_agreement":null},{"id":"W3081364704","doi":"10.2174/1568026620666200819145526","title":"Antimicrobial, Antitumor and Side Effects Assessment of a Newly Synthesized Tamoxifen Analog","year":2020,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Wilfrid Laurier University; University of Ottawa","funders":"","keywords":"Tamoxifen; Pharmacology; Antimicrobial; Medicine; Antiparasitic; Side effect (computer science); Drug; Internal medicine; Cancer; Breast cancer; Chemistry","score_opus":0.009651203475865122,"score_gpt":0.28343766600053594,"score_spread":0.2737864625246708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081364704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99356365,0.004187062,0.0007694053,0.000054468856,0.000024164992,0.00006614029,0.00032727412,0.000014672052,0.0009932967],"genre_scores_gemma":[0.99060154,0.0038166146,0.0032200199,0.000071764975,0.00002597785,0.000056704215,0.0006541568,0.0000052860873,0.0015479166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999602,0.000009354093,0.0000038524013,0.000007209193,0.000012830345,0.000006539589],"domain_scores_gemma":[0.99991894,0.000012349838,0.000022360664,0.000005110576,0.00002278317,0.000018411913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008875584,0.0002519721,0.0001718004,0.00030340411,0.00008233518,0.000104149745,0.00014327599,0.00020614476,0.0010399513],"category_scores_gemma":[0.0001136722,0.00006557047,0.00018160985,0.00014955905,0.00008808048,0.00014366438,0.00007484858,0.00021730436,0.00012954877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003261394,0.00016935887,0.0002519842,0.00016820942,0.000013934833,0.00009027168,0.000016843229,0.00018664882,0.9952584,0.000028822253,0.000045483404,0.0034440106],"study_design_scores_gemma":[0.0002049557,0.026105339,0.007896059,0.00004228399,0.00013937485,0.000794576,0.00005749569,0.0007715248,0.9577095,0.000031425312,0.006226477,0.000021053576],"about_ca_topic_score_codex":0.00021917064,"about_ca_topic_score_gemma":0.00053694134,"teacher_disagreement_score":0.0010399513,"about_ca_system_score_codex":0.00008458602,"about_ca_system_score_gemma":0.0001318945,"threshold_uncertainty_score":0.003479004},"labels":[],"label_agreement":null},{"id":"W3139613220","doi":"10.2174/1568026621666210331161144","title":"Predicting Metabolic Reaction Networks with Perturbation-Theory Machine Learning (PTML) Models","year":2021,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España; Eusko Jaurlaritza; Office of Experimental Program to Stimulate Competitive Research; North Dakota Established Program to Stimulate Competitive Research; North Dakota State University","keywords":"Bayesian network; Computer science; Random forest; Machine learning; Metabolic network; Linear model; Artificial intelligence; Algorithm; Bioinformatics","score_opus":0.009444153107229313,"score_gpt":0.22938416617043692,"score_spread":0.2199400130632076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139613220","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15948069,0.00040356428,0.836359,0.00030855357,0.000028733612,0.00008695329,0.0007060043,0.0012021438,0.0014244233],"genre_scores_gemma":[0.8790257,0.00023108273,0.118983306,0.00006644535,0.000027115515,0.00015806187,0.00071655697,0.00007031245,0.0007213417],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99958676,0.00019485492,0.000018180262,0.00010658642,0.00006648719,0.000027086679],"domain_scores_gemma":[0.9967103,0.002628719,0.00031159926,0.00013265328,0.00016378165,0.00005289808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094643165,0.0007398599,0.00051028247,0.0010797817,0.00029423754,0.00067770394,0.00065096916,0.00074910943,0.0010133098],"category_scores_gemma":[0.0054450254,0.00030538792,0.0009904923,0.0006167923,0.0005054469,0.00096644997,0.0005054048,0.0009049955,0.00028251013],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025141562,0.000015559088,0.001352309,0.00002834911,0.000018931463,0.000019622084,0.000010620185,0.99054074,0.00056610076,0.0015480533,0.00012211564,0.0057524946],"study_design_scores_gemma":[8.9440306e-7,0.000004315123,0.00010029228,0.000001029165,0.0000018232254,0.0000036445995,0.0000012029059,0.9981511,0.00016760435,0.0015300937,0.000036666803,0.0000012873497],"about_ca_topic_score_codex":0.0047900155,"about_ca_topic_score_gemma":0.0036857456,"teacher_disagreement_score":0.0047900155,"about_ca_system_score_codex":0.0012070886,"about_ca_system_score_gemma":0.00067080907,"threshold_uncertainty_score":0.009524226},"labels":[],"label_agreement":null},{"id":"W3198782994","doi":"10.2174/1568026621666210909160210","title":"Investigation of the Relationship among Cortisol, Pro-inflammatoryCytokines, and the Degradation of Tryptophan into Kynurenine inPatients with Major Depression and Suicidal Behavior","year":2021,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; McGill University Health Centre","funders":"","keywords":"Major depressive disorder; Proinflammatory cytokine; Kynurenine; Internal medicine; Depression (economics); Endocrinology; Medicine; Inflammation; Tryptophan; Psychology; Chemistry; Amygdala; Biochemistry","score_opus":0.02827212171219867,"score_gpt":0.26852991844353896,"score_spread":0.2402577967313403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198782994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9997255,0.00012405301,0.000022896022,0.000012960493,0.0000017870228,0.0000032621274,0.000035137797,7.1309097e-7,0.000073607145],"genre_scores_gemma":[0.9997991,0.00005715816,0.000033951364,0.0000062942636,0.0000026169548,0.0000031717198,0.000057264224,2.2354891e-7,0.0000402296],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99980325,0.000053600033,0.000027768612,0.000033541273,0.000043600954,0.00003829836],"domain_scores_gemma":[0.9993573,0.000098800905,0.00028268262,0.00002600597,0.00009515528,0.0001399729],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031787134,0.00020386775,0.00032635612,0.0003790946,0.00023729022,0.00037116156,0.0001235183,0.00022489233,0.0009657899],"category_scores_gemma":[0.0011363438,0.00015485474,0.00017310849,0.0002864051,0.0001590902,0.00014599824,0.00023153913,0.00037337892,0.0001678346],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017172183,0.000050500137,0.997715,0.000011869514,0.000041766863,0.00007173959,0.00010317917,0.000013304994,0.0006059881,0.0000060057705,0.00002467794,0.0011842434],"study_design_scores_gemma":[0.0000050030167,0.00017604095,0.9991437,0.000003365947,0.000019930685,0.00023618182,0.0001802667,0.000081903665,0.00010250326,0.000008841219,0.000040830724,0.0000014045144],"about_ca_topic_score_codex":0.0010460593,"about_ca_topic_score_gemma":0.0017704488,"teacher_disagreement_score":0.0010460593,"about_ca_system_score_codex":0.00024799755,"about_ca_system_score_gemma":0.00019870074,"threshold_uncertainty_score":0.0032309294},"labels":[],"label_agreement":null},{"id":"W3205803446","doi":"10.2174/1568026621666211012111901","title":"Therapeutic Potential of Indole Derivatives as Anti-HIV Agents: AMini-review","year":2021,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Henan Provincial Science and Technology Research Project; Key Scientific Research Project of Colleges and Universities in Henan Province; Henan Province Science and Technology Innovation Talent Program","keywords":"Indole test; Human immunodeficiency virus (HIV); Pharmacology; Medicine; Chemistry; Virology; Stereochemistry","score_opus":0.08487877388222492,"score_gpt":0.41003750493860147,"score_spread":0.32515873105637655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3205803446","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006378033,0.9968773,0.00020660403,0.00010960442,0.0002295146,0.000008823486,0.000023477338,0.000010638559,0.0018962262],"genre_scores_gemma":[0.0024292353,0.99592614,0.0002424333,0.00012205982,0.00015125092,0.0000097413595,0.000038054965,0.000001676945,0.0010795144],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.999918,0.000011685859,0.000009241402,0.000016390002,0.000031407657,0.000013289444],"domain_scores_gemma":[0.99991083,0.00003797651,0.000016417764,0.00000308308,0.000021240654,0.000010432343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023816492,0.0007235046,0.0007059022,0.0016155712,0.00021230661,0.0005809493,0.0005271512,0.0005695001,0.0030011511],"category_scores_gemma":[0.0002568379,0.00022768437,0.00038022,0.0014589666,0.00019724124,0.00078790134,0.00035550096,0.00084115023,0.0013576366],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011385654,0.00014016217,0.00018545413,0.022752909,0.00008316699,0.0003841706,0.00008797279,0.0006497096,0.011404086,0.0044553475,0.02012138,0.9396218],"study_design_scores_gemma":[0.000019581561,0.00026003312,0.0007732322,0.0016085026,0.00011604939,0.001344376,0.00005812153,0.0001923751,0.0034936736,0.0010365628,0.9910767,0.000020708105],"about_ca_topic_score_codex":0.00040072127,"about_ca_topic_score_gemma":0.00079750887,"teacher_disagreement_score":0.0030011511,"about_ca_system_score_codex":0.0002948517,"about_ca_system_score_gemma":0.00042033175,"threshold_uncertainty_score":0.010039866},"labels":[],"label_agreement":null},{"id":"W4238309752","doi":"10.2174/156802609789630956","title":"Endogenous Opioids and Addiction to Alcohol and other Drugs of Abuse","year":2009,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Nucleus accumbens; Endogenous opioid; Ventral tegmental area; Opioid; Dopamine; Addiction; Brain stimulation reward; Pharmacology; Neuroscience; Mesolimbic pathway; Opioid peptide; Dopamine receptor; Medicine; Psychology; Receptor; Internal medicine; Dopaminergic","score_opus":0.05165786898545973,"score_gpt":0.308321307895854,"score_spread":0.2566634389103943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238309752","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04181401,0.9320732,0.00046700906,0.003985779,0.00047185385,0.000026629823,0.00016296418,0.000016271499,0.020982377],"genre_scores_gemma":[0.16638589,0.81653523,0.0005232833,0.0012202795,0.0008413318,0.000034026365,0.00018392726,0.0000032139671,0.014272815],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99986565,0.00003832443,0.0000124202115,0.000014222606,0.000046477046,0.000022899363],"domain_scores_gemma":[0.9998659,0.000025051315,0.000050143954,0.0000048927072,0.000025077514,0.000028891774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001978555,0.0002342611,0.00027495335,0.00053954544,0.00035359885,0.00045020078,0.00019293906,0.0005064925,0.004157296],"category_scores_gemma":[0.0003483928,0.000069051806,0.00014597707,0.0007287365,0.00041350353,0.00026115146,0.00046713985,0.0006002537,0.0005833421],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005287715,0.000615477,0.043380186,0.0036070498,0.0002374779,0.0060844887,0.0010162985,0.00034042515,0.016894788,0.040467173,0.023310803,0.863517],"study_design_scores_gemma":[0.000051016483,0.0006736701,0.31276053,0.0014384991,0.00018996834,0.015736736,0.0009612033,0.00029972015,0.0031929077,0.026121031,0.63852715,0.0000475633],"about_ca_topic_score_codex":0.0025764743,"about_ca_topic_score_gemma":0.005136854,"teacher_disagreement_score":0.004157296,"about_ca_system_score_codex":0.00042300054,"about_ca_system_score_gemma":0.00054207386,"threshold_uncertainty_score":0.013907552},"labels":[],"label_agreement":null},{"id":"W4285802297","doi":"10.2174/1568026622666220718155616","title":"Indoleamine 2,3-dioxygenase (IDO)-activity in Severe Psychiatric Disorders:A Systemic Review","year":2022,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Kynurenine; Kynurenine pathway; Bipolar disorder; Schizophrenia (object-oriented programming); Indoleamine 2,3-dioxygenase; Depression (economics); Psychiatry; Medicine; Major depressive disorder; Psychosis; Internal medicine; Clinical psychology; Tryptophan; Cognition; Biology; Genetics","score_opus":0.06987022219642954,"score_gpt":0.35690398639098453,"score_spread":0.287033764194555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285802297","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00013056607,0.99959964,0.000023889474,0.000072621144,0.00005282288,0.000005124784,0.000024428653,0.0000017146782,0.00008914258],"genre_scores_gemma":[0.0012269666,0.9984378,0.000095577816,0.000099378565,0.00005627122,0.000010153496,0.000027629612,6.9077413e-7,0.000045462086],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9994301,0.00013044674,0.00020281147,0.00008605655,0.0001136872,0.00003690876],"domain_scores_gemma":[0.99715805,0.0019696692,0.00045900547,0.000038885635,0.00031290532,0.000061574414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012492214,0.0009569588,0.0028148913,0.0057084775,0.00034569652,0.0015082426,0.00092777604,0.0011663046,0.0024429997],"category_scores_gemma":[0.0031688246,0.000413564,0.0020659282,0.00550134,0.00040501414,0.0011126195,0.000670654,0.00077971077,0.00035182727],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022593555,0.000051613857,0.00100109,0.6052416,0.0017512976,0.00028844926,0.00025019294,0.0002858983,0.0009665134,0.000997971,0.011065818,0.37787363],"study_design_scores_gemma":[0.00011775511,0.00055038254,0.011237364,0.5283676,0.020586232,0.0040184543,0.0005992366,0.00027550518,0.0009074577,0.0021073485,0.43114585,0.0000868453],"about_ca_topic_score_codex":0.0023912224,"about_ca_topic_score_gemma":0.0046511726,"teacher_disagreement_score":0.0057084775,"about_ca_system_score_codex":0.0008685357,"about_ca_system_score_gemma":0.0037994354,"threshold_uncertainty_score":0.008172631},"labels":[],"label_agreement":null},{"id":"W4383301604","doi":"10.2174/1568026623666230705151922","title":"Addressing the Current Knowledge and Gaps in Research SurroundingLysergic Acid Diethylamide (LSD), Psilocybin, and Psilocin in RodentModels","year":2023,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Psilocybin; Lysergic acid diethylamide; Hallucinogen; Pharmacology; Dosing; Anxiety; Psychology; Drug; Psychiatry; Medicine; Serotonin; Internal medicine","score_opus":0.6068513973661902,"score_gpt":0.5897009987026134,"score_spread":0.017150398663576816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383301604","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034677048,0.9979779,0.00019424151,0.0002764238,0.00008352391,0.0000069423572,0.000033203498,0.00000832368,0.0010727517],"genre_scores_gemma":[0.0012473441,0.99795294,0.0002664036,0.00016130804,0.00008501982,0.000009199496,0.000038746173,0.0000014928972,0.00023764693],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9997744,0.000044414748,0.00004978421,0.00004749799,0.00006360329,0.000020204403],"domain_scores_gemma":[0.9990965,0.0005437621,0.00013432468,0.00003045375,0.0001503394,0.00004457901],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010700857,0.0006452245,0.0013420173,0.0019575087,0.00028858194,0.0012262558,0.00082768913,0.00095371803,0.004471045],"category_scores_gemma":[0.0012140117,0.00025717655,0.00045662248,0.0017992252,0.00059504196,0.001630857,0.00066105643,0.0013953787,0.0015197564],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014065305,0.00013682745,0.0002741992,0.051651414,0.00009296732,0.00021182351,0.00013177481,0.00023693172,0.005305572,0.0044107814,0.0073026204,0.93010443],"study_design_scores_gemma":[0.000038165577,0.00051805517,0.0030705056,0.01831152,0.00058814435,0.0018557683,0.00038247366,0.00017916539,0.0035632076,0.005771651,0.96567184,0.00004952086],"about_ca_topic_score_codex":0.0010282804,"about_ca_topic_score_gemma":0.0021573533,"teacher_disagreement_score":0.004471045,"about_ca_system_score_codex":0.00042651553,"about_ca_system_score_gemma":0.0020653808,"threshold_uncertainty_score":0.01495707},"labels":[],"label_agreement":null},{"id":"W4399384577","doi":"10.2174/0115680266295587240522050712","title":"Gallocin-derived Engineered Peptides Targeting EGFR and VEGFR inColorectal Cancer: A Bioinformatic Approach","year":2024,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Colorectal cancer; VEGF receptors; Cancer research; Computational biology; Cancer; Medicine; Biology; Internal medicine","score_opus":0.015330801560846317,"score_gpt":0.2769592504497067,"score_spread":0.2616284488888604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399384577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60347134,0.004344968,0.37493762,0.001049122,0.00014783996,0.00044470766,0.003888658,0.0054614316,0.006254296],"genre_scores_gemma":[0.72684693,0.002812108,0.26184192,0.00033937517,0.00004061504,0.00025059897,0.004850352,0.00032677193,0.0026913476],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99987125,0.000020582327,0.000010384245,0.00003619998,0.00004631647,0.000015218531],"domain_scores_gemma":[0.9998791,0.000034357105,0.00003626367,0.000006810987,0.000027782482,0.000015675036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030471524,0.0005741133,0.0005020603,0.0007310459,0.00023181878,0.00091596623,0.0003861424,0.0004096143,0.0014561393],"category_scores_gemma":[0.0005839977,0.00019988685,0.00072854635,0.00046684075,0.00015878165,0.00042747837,0.0002979539,0.00048151243,0.00042452812],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009958565,0.00052237697,0.009029661,0.0016605563,0.00027465788,0.0012738346,0.00018256663,0.100714885,0.7195811,0.0041420916,0.002727559,0.15889485],"study_design_scores_gemma":[0.00012874338,0.0009239622,0.008868413,0.000110465786,0.00044306958,0.0016354623,0.00020532875,0.72962147,0.23504616,0.004200942,0.018727379,0.0000886681],"about_ca_topic_score_codex":0.00065540796,"about_ca_topic_score_gemma":0.0006705738,"teacher_disagreement_score":0.0014561393,"about_ca_system_score_codex":0.00044394447,"about_ca_system_score_gemma":0.00047184993,"threshold_uncertainty_score":0.004871249},"labels":[],"label_agreement":null},{"id":"W4404122346","doi":"10.2174/0115680266337668241025061804","title":"Computer-aided Drug Discovery of Epigenetic Modulators in Dual-target Therapy of Multifactorial Diseases","year":2024,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Faculté de pharmacie, Université de Montréal; European Cooperation in Science and Technology; Univerzitet u Beogradu","keywords":"Epigenetics; Vorinostat; Neurodegeneration; Drug discovery; Histone deacetylase; Biology; microRNA; Epigenetic therapy; Bioinformatics; Computational biology; Cancer research; Histone; DNA methylation; Neuroscience; Medicine; Genetics; Gene expression; Gene; Disease","score_opus":0.014065777063435992,"score_gpt":0.29465952681845614,"score_spread":0.28059374975502016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404122346","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11749722,0.06804568,0.78784895,0.0017365062,0.00025170943,0.00054466206,0.001572387,0.0026523026,0.01985063],"genre_scores_gemma":[0.49812746,0.042546034,0.44849676,0.0005076051,0.000085412416,0.00083237817,0.0016679496,0.00013548502,0.007600912],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9998282,0.000056590306,0.000009625009,0.000027454422,0.00006179343,0.000016283278],"domain_scores_gemma":[0.9999151,0.00004683218,0.000016567617,0.000004907341,0.000011284113,0.0000052837618],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004978255,0.0006895294,0.0010474708,0.00045760747,0.00016016021,0.00058689876,0.00044682255,0.0004412012,0.0019693063],"category_scores_gemma":[0.00043041428,0.0002940844,0.0007119373,0.0005411354,0.00022994084,0.00036193957,0.0005247536,0.000589995,0.0004499532],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042749193,0.00024671524,0.0013236525,0.0028304323,0.00037995173,0.00043895925,0.000074508614,0.5222377,0.12770225,0.03242669,0.005365787,0.30654588],"study_design_scores_gemma":[0.00024649626,0.00073563657,0.00075102295,0.00009824205,0.0001800384,0.0003362255,0.00003162867,0.8888858,0.05438197,0.01015701,0.04413281,0.00006308796],"about_ca_topic_score_codex":0.0009560543,"about_ca_topic_score_gemma":0.001989562,"teacher_disagreement_score":0.0019693063,"about_ca_system_score_codex":0.0005311681,"about_ca_system_score_gemma":0.0006740318,"threshold_uncertainty_score":0.006587982},"labels":[],"label_agreement":null},{"id":"W7946861","doi":"10.2174/1568026054367610","title":"Voltage Gated Calcium Channels as Targets for Analgesics","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Neuroscience; Voltage-dependent calcium channel; Sodium channel; Neurotransmission; Noxious stimulus; Ion channel; Nociception; Medicine; T-type calcium channel; Potassium channel; Calcium; Chemistry; Biology; Receptor; Sodium; Internal medicine","score_opus":0.1024904714632812,"score_gpt":0.42445119626387157,"score_spread":0.32196072480059035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7946861","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00028369704,0.9969965,0.00027277516,0.00036298417,0.00027033073,0.0000063731104,0.000008538418,0.00001075627,0.0017878971],"genre_scores_gemma":[0.0019109964,0.9954371,0.00042707892,0.00032967626,0.00030353593,0.00000874741,0.00001862837,0.0000017904641,0.0015625013],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998085,0.000034420107,0.00002015907,0.000031479634,0.000079236146,0.0000261998],"domain_scores_gemma":[0.9998431,0.000058925343,0.00002163787,0.000005611871,0.000051503837,0.000019108194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058585056,0.00083078333,0.0012521584,0.0016879997,0.00033643216,0.00078517606,0.0008901284,0.0012198631,0.004163693],"category_scores_gemma":[0.00046082571,0.00026537623,0.00038994406,0.0014580514,0.00054484827,0.0017076161,0.00046339753,0.0016917759,0.002863268],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021000532,0.0001780155,0.00017733467,0.010988459,0.00005773093,0.0006608231,0.0000945143,0.00062849856,0.015090637,0.010463869,0.026041688,0.9354084],"study_design_scores_gemma":[0.00006866144,0.0002355779,0.00081422017,0.0017319099,0.000076837496,0.0016724607,0.00007972976,0.00023663214,0.0035112507,0.006475351,0.985076,0.000021315058],"about_ca_topic_score_codex":0.0005475056,"about_ca_topic_score_gemma":0.0010025176,"teacher_disagreement_score":0.004163693,"about_ca_system_score_codex":0.0006944597,"about_ca_system_score_gemma":0.00072953117,"threshold_uncertainty_score":0.01392889},"labels":[],"label_agreement":null}]}