{"meta":{"query_hash":"4a4253388019","filters":{"venue":"Expert Opinion on Therapeutic Targets"},"cohort_total":89,"direct_labels_cover":1,"predictions_cover":89,"exported":89,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/4a4253388019","api":"https://metacan.xera.ac/api/v1/cohort?venue=Expert+Opinion+on+Therapeutic+Targets"},"results":[{"id":"W1965301111","doi":"10.1517/14728222.2011.537656","title":"The promise and challenges of targeting RSK for the treatment of cancer","year":2010,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Kinase; Serine; Threonine; Protein-Serine-Threonine Kinases; Biology; Phosphorylation; Cancer; Cancer research; Ribosomal s6 kinase; Cell biology; Genetics; Protein kinase A; Protein kinase B","score_opus":0.03705129146068916,"score_gpt":0.315687583912151,"score_spread":0.2786362924514619,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965301111","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12972213,0.8621108,0.00018564158,0.004925274,0.001749554,0.0010226453,0.000041611787,0.0000092381,0.00023307775],"genre_scores_gemma":[0.8026144,0.1963223,0.0001873563,0.00008647243,0.00040549802,0.00027983438,0.000010944937,0.000015114519,0.0000780709],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994806,0.000027243472,0.00013818349,0.00015873632,0.00006550321,0.00012971488],"domain_scores_gemma":[0.99949473,0.00009472292,0.00009387356,0.00024089204,0.00004941738,0.000026353338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120900535,0.00010422043,0.000107571,0.000009385394,0.000119155084,0.0000053886874,0.000110334964,0.00007034424,0.0000072414664],"category_scores_gemma":[0.000017766006,0.00005193818,0.0000683768,0.000012948468,0.00009896483,0.000001314505,0.000013782518,0.000029586154,2.2442839e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025668807,0.00011981595,0.00012300117,0.000013692231,0.00012844772,4.8642203e-8,0.001055006,0.0000020949826,0.69970274,0.0026119747,0.00025616214,0.29573032],"study_design_scores_gemma":[0.00042908275,0.0007072011,0.00053090655,0.000004634447,0.000003211119,4.847493e-7,0.00023076656,0.00004848463,0.42119718,0.000102466285,0.5766961,0.00004947952],"about_ca_topic_score_codex":0.000021426522,"about_ca_topic_score_gemma":0.000036149362,"teacher_disagreement_score":0.6728923,"about_ca_system_score_codex":0.0000035143305,"about_ca_system_score_gemma":0.000030456973,"threshold_uncertainty_score":0.21179774},"labels":[],"label_agreement":null},{"id":"W1965676778","doi":"10.1517/14728220802600715","title":"PCSK9 as a therapeutic target of dyslipidemia","year":2008,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"PCSK9; Dyslipidemia; Proprotein convertase; Medicine; Pharmacology; Internal medicine; Cholesterol; Disease; LDL receptor; Lipoprotein","score_opus":0.07195171311946463,"score_gpt":0.38167704167601885,"score_spread":0.3097253285565542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965676778","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[7.7406577e-7,0.9909759,0.0002922903,0.00033301537,0.0020402942,0.002896266,0.000037327456,0.00017813648,0.0032460073],"genre_scores_gemma":[0.00006258914,0.9930178,0.0006089295,0.002516408,0.0021100426,0.00051244523,0.00036190802,0.00028534277,0.0005245391],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99442977,0.0007255845,0.0015324636,0.0010685856,0.0014057617,0.00083785783],"domain_scores_gemma":[0.9962703,0.0002584258,0.00076080405,0.0020787593,0.00019487827,0.0004368065],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00061672076,0.0010998483,0.0047180527,0.0004991194,0.00019328047,0.000018805687,0.0004863013,0.0009910499,0.0008413171],"category_scores_gemma":[0.00008264106,0.0007818529,0.0030148788,0.0005783422,0.00021756774,0.000074130585,0.00008464288,0.0010963707,0.00048455998],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012865648,0.00043476527,0.0000019702754,0.0040022586,0.0020955869,0.00003834536,0.00040482255,7.634312e-7,0.000007742922,0.0007610261,0.0022093311,0.9899147],"study_design_scores_gemma":[0.0012513079,0.0011524851,0.000012912547,0.007959394,0.00016951197,0.00050876394,0.000052706404,0.000007843058,0.000100995894,0.00018218614,0.98794323,0.00065865065],"about_ca_topic_score_codex":0.00006523613,"about_ca_topic_score_gemma":3.715294e-7,"teacher_disagreement_score":0.9892561,"about_ca_system_score_codex":0.00038332553,"about_ca_system_score_gemma":0.0015345749,"threshold_uncertainty_score":0.99946326},"labels":[],"label_agreement":null},{"id":"W1970143948","doi":"10.1517/14728222.12.3.327","title":"Therapeutic targets in hypertension: is there a place for antagonists of the most potent vasoconstrictors?","year":2008,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Urotensin-II; Endothelin receptor; Pathogenesis; Pathophysiology; Vasodilation; Receptor; Medicine; Internal medicine; Pharmacology; Endothelin 1; Endocrinology","score_opus":0.09739691803559454,"score_gpt":0.36964368708675666,"score_spread":0.27224676905116213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970143948","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000010167676,0.99208313,0.00010015473,0.000634609,0.0013309192,0.0049737827,0.00020650972,0.000057149937,0.0006035811],"genre_scores_gemma":[0.0009915202,0.995191,0.00010192088,0.0015508832,0.0006011093,0.00065098866,0.00020373701,0.00022649637,0.00048237966],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99455494,0.00087393966,0.0012155388,0.0011633944,0.0013066492,0.00088551326],"domain_scores_gemma":[0.99637157,0.00084164704,0.0005299002,0.0016902963,0.00033390566,0.00023266622],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040101036,0.0010094973,0.0031252024,0.00047157932,0.00029488353,0.000039251277,0.0007574072,0.00058087974,0.000187765],"category_scores_gemma":[0.00014713136,0.0006070081,0.002549017,0.0009031232,0.0004693576,0.00007517498,0.00019286684,0.0010816583,0.00003458206],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003817433,0.0007659055,0.00005483687,0.002536567,0.0017715564,0.00007798055,0.00087655673,0.000003813415,0.00007900671,0.000112364716,0.007863378,0.9854763],"study_design_scores_gemma":[0.0025640486,0.0005905067,0.00030206164,0.0066660526,0.00013637361,0.0004517161,0.00017674302,0.000042362444,0.0005914097,0.000025494968,0.9878919,0.0005613386],"about_ca_topic_score_codex":0.000069423535,"about_ca_topic_score_gemma":0.000004136828,"teacher_disagreement_score":0.98491496,"about_ca_system_score_codex":0.000372713,"about_ca_system_score_gemma":0.0010264926,"threshold_uncertainty_score":0.99963814},"labels":[],"label_agreement":null},{"id":"W1971264300","doi":"10.1517/14728222.12.3.313","title":"CD4<sup>+</sup>CD25<sup>+</sup>regulatory T cells: a therapeutic target for liver diseases","year":2008,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Immune system; Immunology; Immunity; IL-2 receptor; Regulatory T cell; Homeostasis; FOXP3; Peripheral tolerance; Disease; Biology; Immune tolerance; Medicine; Cancer research; T cell; Cell biology; Internal medicine","score_opus":0.06504250241665019,"score_gpt":0.3380372406764606,"score_spread":0.27299473825981047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971264300","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00001964877,0.9902669,0.00037137722,0.00031515103,0.0012724298,0.005737267,0.0011523457,0.0005268204,0.00033803625],"genre_scores_gemma":[0.00047442125,0.9838163,0.00058257615,0.0049287896,0.0029664394,0.0019011723,0.003247926,0.000631387,0.0014509691],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9922718,0.0009959232,0.0017276073,0.0019568973,0.0013583562,0.0016894221],"domain_scores_gemma":[0.9939349,0.0010989684,0.00077385304,0.0027085145,0.00038518925,0.0010985337],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00032289524,0.0022505822,0.004303655,0.0007372821,0.00085990893,0.00013642425,0.0011624129,0.0011221251,0.0020668814],"category_scores_gemma":[0.000088971385,0.0017544094,0.0038273798,0.0006098433,0.00054195814,0.0003374358,0.0002500396,0.0011859034,0.0006535093],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011709387,0.0035442922,0.000037639213,0.008302754,0.0041552307,0.00008376974,0.0023260142,0.00009273761,0.0000066992548,0.00044483095,0.049006775,0.93082833],"study_design_scores_gemma":[0.0031828985,0.0018572079,0.000080810416,0.006488772,0.0009682711,0.00013271256,0.00039779858,0.0019097308,0.000035394856,0.00015731175,0.9829945,0.0017945722],"about_ca_topic_score_codex":0.000053079704,"about_ca_topic_score_gemma":2.0731402e-7,"teacher_disagreement_score":0.93398774,"about_ca_system_score_codex":0.00081423536,"about_ca_system_score_gemma":0.0016401219,"threshold_uncertainty_score":0.9990234},"labels":[],"label_agreement":null},{"id":"W1973606269","doi":"10.1517/14728220903531454","title":"Targeting DAX-1 in embryonic stem cells and cancer","year":2010,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Institute of Cancer Research; Institut National Du Cancer; Ministerio de Ciencia e Innovación; Fundación Científica Asociación Española Contra el Cáncer; Agence Nationale de la Recherche","keywords":"Embryonic stem cell; Stem cell; Biology; Neuroscience; Transcription factor; Nuclear receptor; Cancer; Drug discovery; Cancer stem cell; Drug development; Cancer cell; Bioinformatics; Cancer research; Cell biology; Drug; Pharmacology; Genetics; Gene","score_opus":0.03857099482044137,"score_gpt":0.34537274292948394,"score_spread":0.3068017481090426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973606269","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000100205354,0.9978385,0.000013452638,0.00010962418,0.0012547098,0.0003871971,0.00004108038,0.000016360747,0.00023888805],"genre_scores_gemma":[0.00047782643,0.9965397,0.000059564052,0.00066675694,0.00069510046,0.00018195735,0.00011906228,0.000059414604,0.0012006224],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99819094,0.00015449354,0.0005058296,0.0006285576,0.00016901287,0.00035115203],"domain_scores_gemma":[0.9992373,0.0000595328,0.00023008254,0.00031706176,0.000037270802,0.00011872887],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017992624,0.00043629715,0.0007205944,0.000081330305,0.00008736996,0.00004486881,0.00028557383,0.0005994716,0.00012233875],"category_scores_gemma":[0.0000080391865,0.0003451684,0.00020632242,0.00007388004,0.00010988737,0.000004493907,0.000110427565,0.00041623705,0.000024517823],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019516034,0.00008183662,0.0000041876015,0.000397903,0.00005126472,0.000002487933,0.00008348948,0.0000014170154,0.000670756,0.00007163114,0.0006134906,0.998002],"study_design_scores_gemma":[0.00031098968,0.00025593454,0.000004573565,0.0008048298,0.000010545878,0.000007312289,0.00011039292,0.000008516201,0.00096797425,0.000020439962,0.9970718,0.00042669347],"about_ca_topic_score_codex":0.000009750247,"about_ca_topic_score_gemma":0.0000065406116,"teacher_disagreement_score":0.99757534,"about_ca_system_score_codex":0.000023200564,"about_ca_system_score_gemma":0.00013875305,"threshold_uncertainty_score":0.99990004},"labels":[],"label_agreement":null},{"id":"W1978308081","doi":"10.1517/14728222.2011.638626","title":"Targeting the insulin-like growth factor 1 receptor (IGF1R) signaling pathway for cancer therapy","year":2012,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Insulin-like growth factor 1 receptor; Insulin receptor; Insulin-Like Growth Factor Receptor; Signal transduction; Insulin-like growth factor; Cancer; Carcinogenesis; Growth factor receptor; Receptor; Biology; Cancer research; Growth factor; Medicine; Insulin resistance; Insulin; Internal medicine; Endocrinology; Cell biology","score_opus":0.1186887029938829,"score_gpt":0.36218737222166775,"score_spread":0.24349866922778485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978308081","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000017946439,0.9840806,0.00034466895,0.0008633188,0.008507568,0.00533966,0.00039952458,0.0003163629,0.00013035382],"genre_scores_gemma":[0.0007103787,0.9823849,0.0004676415,0.004765807,0.0065529076,0.0030179117,0.0012383997,0.00053046306,0.0003315659],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99382025,0.0006031113,0.0017376026,0.0012804851,0.0009914332,0.0015671393],"domain_scores_gemma":[0.9956398,0.0012525561,0.0010991577,0.0010604328,0.00041641484,0.00053162914],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00085258426,0.0016930177,0.0030287013,0.00034863077,0.00072600984,0.00012549308,0.0008808147,0.0011184684,0.0010135286],"category_scores_gemma":[0.00014459668,0.000994297,0.0017594639,0.00061851664,0.00020037162,0.00025424108,0.00010859645,0.0014581176,0.00020008968],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041036328,0.00051260367,0.000019971467,0.0018811492,0.0013818449,0.0000021561198,0.002279688,5.893118e-7,0.0006984246,0.00024205672,0.008098339,0.9844728],"study_design_scores_gemma":[0.0016773585,0.000834641,0.000012033617,0.003141316,0.00015328897,0.000013308858,0.00018344112,0.00001360336,0.001027909,0.000047676287,0.991743,0.0011523903],"about_ca_topic_score_codex":0.000054282198,"about_ca_topic_score_gemma":6.806627e-7,"teacher_disagreement_score":0.9836447,"about_ca_system_score_codex":0.000567547,"about_ca_system_score_gemma":0.00079635595,"threshold_uncertainty_score":0.9998997},"labels":[],"label_agreement":null},{"id":"W1980561165","doi":"10.1517/14728222.2014.941285","title":"Long noncoding RNAs in liver cancer: what we know in 2014","year":2014,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"Epigenetics; Hepatocellular carcinoma; In silico; Biology; Non-coding RNA; Bioinformatics; Long non-coding RNA; microRNA; Cancer; Liver cancer; Gene; Computational biology; Medicine; RNA; Cancer research; Genetics","score_opus":0.04810450334453387,"score_gpt":0.3857445742934832,"score_spread":0.3376400709489493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980561165","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[8.748302e-7,0.9946985,0.0018964394,0.00024663465,0.0018921951,0.0010815402,0.000010222486,0.000020066645,0.00015349248],"genre_scores_gemma":[0.00006708738,0.9969777,0.000080696314,0.00055483804,0.00081008696,0.00070147205,0.0003130004,0.00017180535,0.00032334978],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996315,0.0006596126,0.00069377205,0.0011279093,0.00042440183,0.0007792996],"domain_scores_gemma":[0.9986087,0.00007541917,0.0002663691,0.0008396883,0.000050368595,0.0001594406],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053447805,0.0006731063,0.0011918129,0.00048132022,0.0000703387,0.00010694905,0.00069013576,0.00098284,0.00021784482],"category_scores_gemma":[0.00003695879,0.0006175274,0.0004373792,0.00031906232,0.000074573785,0.000015697717,0.00022841546,0.0008039998,0.00011718513],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006667189,0.00011015537,9.196357e-7,0.0007628733,0.0001249916,0.000022679375,0.00012546864,0.000024879175,0.0006811844,0.000041994062,0.0016184564,0.9964197],"study_design_scores_gemma":[0.00070006785,0.0002679719,0.0000016613146,0.011802786,0.000010694775,0.000018780831,0.000032439002,0.00013612432,0.0024559256,0.00001730708,0.98391724,0.000639004],"about_ca_topic_score_codex":0.00014864512,"about_ca_topic_score_gemma":0.00022483994,"teacher_disagreement_score":0.9957807,"about_ca_system_score_codex":0.00042440565,"about_ca_system_score_gemma":0.00049120426,"threshold_uncertainty_score":0.9996276},"labels":[],"label_agreement":null},{"id":"W1982661637","doi":"10.1517/14728222.9.5.901","title":"Spleen tyrosine kinase (Syk) as a novel target for allergic asthma and rhinitis","year":2005,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University; NOSM University; University of Alberta","funders":"","keywords":"Syk; Immunology; Tyrosine kinase; Immune system; Medicine; Inflammation; Cancer research; Signal transduction; Biology; Cell biology","score_opus":0.0501508995772739,"score_gpt":0.331019571064058,"score_spread":0.28086867148678407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982661637","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[5.380152e-7,0.99274385,0.00038826262,0.00049346616,0.0026636508,0.001520139,0.00075776636,0.000117759126,0.0013145752],"genre_scores_gemma":[0.000024333782,0.9877359,0.0007747008,0.0010897788,0.0005781964,0.0005372273,0.0040237214,0.00012960692,0.005106484],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972063,0.00019305422,0.0007953476,0.0009784008,0.00009000762,0.0007368949],"domain_scores_gemma":[0.9984332,0.0003610675,0.00043855552,0.000590575,0.00008013054,0.000096494165],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00026326274,0.00089430984,0.0018525623,0.00028747838,0.00035359684,0.00005155005,0.00042523566,0.0009263042,0.0035685],"category_scores_gemma":[0.000036966547,0.0007187485,0.0005485243,0.00013294884,0.00022876958,0.00007260726,0.000114069844,0.00054281,0.00070204976],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001691295,0.00044879195,1.2621105e-7,0.0007982133,0.00059764384,0.0000039847932,0.00036624048,3.9650288e-7,0.0003292032,0.0039034125,0.017250333,0.9761325],"study_design_scores_gemma":[0.002041839,0.0010845377,0.0000013587897,0.0014109835,0.000046133886,0.00017885049,0.000035000892,0.0000035799087,0.000117004915,0.00007374388,0.9942275,0.00077942736],"about_ca_topic_score_codex":0.000042651864,"about_ca_topic_score_gemma":0.0000062433223,"teacher_disagreement_score":0.9769772,"about_ca_system_score_codex":0.000105219384,"about_ca_system_score_gemma":0.00018144718,"threshold_uncertainty_score":0.9995264},"labels":[],"label_agreement":null},{"id":"W1984861197","doi":"10.1517/14728222.9.4.699","title":"The ERK/MAPK pathway, as a target for the treatment of neuropathic pain","year":2005,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"MAPK/ERK pathway; Neuropathic pain; Peripheral nerve injury; Microglia; Medicine; Phosphorylation; Nerve injury; Protein kinase A; Kinase; Neuroscience; Extracellular; Cell biology; Pharmacology; Anesthesia; Internal medicine; Biology; Sciatic nerve; Inflammation","score_opus":0.08987020680163343,"score_gpt":0.3887323774116298,"score_spread":0.29886217060999637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984861197","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[1.4142555e-7,0.9904787,0.0020116253,0.0011721465,0.001409527,0.0045734663,0.00008740015,0.00007306432,0.00019394139],"genre_scores_gemma":[0.00003890349,0.9926877,0.00046441902,0.001242324,0.0011186881,0.0027454533,0.00023779299,0.00016226078,0.0013024647],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962101,0.0012895605,0.00080720836,0.0006201207,0.00049605523,0.00057694304],"domain_scores_gemma":[0.99462724,0.0033986645,0.0005318029,0.0011873613,0.00009765343,0.00015728766],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016441231,0.00079918915,0.0016132535,0.000114864735,0.000483936,0.00004050835,0.00038070866,0.00032382912,0.00011049574],"category_scores_gemma":[0.00019426353,0.000345427,0.0013636765,0.00018178373,0.000120418925,0.000026171263,0.000025745427,0.0002451487,0.000082338825],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015710521,0.0010005218,3.1090173e-7,0.00035863425,0.001174311,0.000011423448,0.00044088284,7.226194e-7,0.0000072554667,0.0018785828,0.0006666293,0.99430364],"study_design_scores_gemma":[0.0013624564,0.005484183,0.0000013318025,0.0017442937,0.00022725646,0.00004019349,0.00009129572,0.00021505546,0.00012017458,0.0003571796,0.9900755,0.00028104056],"about_ca_topic_score_codex":0.000020660747,"about_ca_topic_score_gemma":0.0000017718257,"teacher_disagreement_score":0.9940226,"about_ca_system_score_codex":0.00029771106,"about_ca_system_score_gemma":0.00043262812,"threshold_uncertainty_score":0.99989974},"labels":[],"label_agreement":null},{"id":"W1985861853","doi":"10.1517/14728220802600707","title":"Regulation of the Na<sup>+</sup>/H<sup>+</sup>exchanger in the healthy and diseased myocardium","year":2008,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Sodium–hydrogen antiporter; Extracellular; Intracellular; Ischemia; Gene isoform; Intracellular pH; Muscle hypertrophy; Cell biology; MAPK/ERK pathway; Chemistry; Kinase; Homeostasis; Phosphorylation; Reperfusion injury; Sodium-calcium exchanger; Internal medicine; Biochemistry; Biology; Endocrinology; Sodium; Medicine","score_opus":0.03546406584183281,"score_gpt":0.30733429336878293,"score_spread":0.2718702275269501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985861853","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004996618,0.99674994,0.00013760768,0.00070616236,0.00037700534,0.0013296679,0.00007063756,0.00001606631,0.00011325316],"genre_scores_gemma":[0.04279108,0.95367473,0.000024859684,0.0011421769,0.00077699847,0.00024163122,0.0011514745,0.000073716204,0.00012330664],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972307,0.00060486264,0.0006777422,0.000633217,0.00046888372,0.0003845707],"domain_scores_gemma":[0.9985805,0.00006817961,0.00034591102,0.0008418161,0.00007690158,0.000086663196],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003099934,0.0005277305,0.0007626271,0.0001354108,0.00021729467,0.000022277545,0.00044851148,0.00054019864,0.0000358814],"category_scores_gemma":[0.000018972027,0.00032114825,0.0005373656,0.0002814629,0.00019794784,0.000010466481,0.00005240655,0.0002880681,0.0000056454737],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007730206,0.00068473717,0.00018776553,0.002515076,0.0005738523,0.000004984803,0.0070592393,0.0010164125,0.00025674418,0.0005071089,0.008606831,0.97781426],"study_design_scores_gemma":[0.0006893827,0.0002611996,0.0006471946,0.0008350756,0.00003449589,0.000024542991,0.00020601298,0.0003953789,0.00013359432,0.000063086416,0.9963347,0.00037535588],"about_ca_topic_score_codex":0.000019218274,"about_ca_topic_score_gemma":0.0000020019838,"teacher_disagreement_score":0.9877278,"about_ca_system_score_codex":0.0000552188,"about_ca_system_score_gemma":0.00021290588,"threshold_uncertainty_score":0.99992406},"labels":[],"label_agreement":null},{"id":"W1988592217","doi":"10.1517/14728222.5.5.557","title":"Cyclin-dependent kinases and stroke","year":2001,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Stroke Network; Heart and Stroke Foundation of Canada","keywords":"Cyclin-dependent kinase; Kinase; Cyclin; Cell cycle; Cell biology; Stroke (engine); Programmed cell death; Biology; Neuroscience; Cancer research; Cell; Apoptosis; Biochemistry","score_opus":0.0312990668304086,"score_gpt":0.31307199963943433,"score_spread":0.2817729328090257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988592217","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2064035,0.70678586,0.0077242893,0.02647695,0.009392652,0.003407615,0.000080163736,0.001292214,0.038436793],"genre_scores_gemma":[0.96814877,0.023670183,0.00033736284,0.006080423,0.0005377978,0.00006061494,0.000043752883,0.000066671004,0.0010544059],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99858576,0.00005653564,0.00023860321,0.00041267253,0.0003752204,0.00033121643],"domain_scores_gemma":[0.99922484,0.000056562178,0.000068562724,0.00039940106,0.000049404716,0.0002012047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001085019,0.00023454342,0.0002815717,0.0001319944,0.000101518446,0.000023520977,0.000082420156,0.00014681986,0.0004689562],"category_scores_gemma":[0.000029213197,0.00020164764,0.00010031539,0.00009749147,0.00007281309,0.000050734212,0.000035082605,0.00024458554,0.00010229104],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029667895,0.0014294446,0.0031527367,0.00004529148,0.00065674394,0.0004010675,0.0029335024,0.000048276295,0.31670493,0.0026703542,0.008021785,0.6609691],"study_design_scores_gemma":[0.0044332426,0.0013999668,0.006258185,0.0001620326,0.000018246814,0.0004109194,0.0003584595,0.00030158367,0.058620304,0.0002457073,0.927402,0.0003893617],"about_ca_topic_score_codex":0.000037802736,"about_ca_topic_score_gemma":0.0000043547,"teacher_disagreement_score":0.9193802,"about_ca_system_score_codex":0.000107007414,"about_ca_system_score_gemma":0.00006106852,"threshold_uncertainty_score":0.8222952},"labels":[],"label_agreement":null},{"id":"W1988923285","doi":"10.1517/14728222.2014.988707","title":"Targeting microglia for the treatment of Alzheimer’s disease","year":2014,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"","keywords":"Microglia; Disease; Medicine; Biomarker; Immunology; Alzheimer's disease; Amyloid (mycology); Inflammation; Neuroscience; Clinical trial; Biology; Pathology","score_opus":0.1191297713207406,"score_gpt":0.42381129557605635,"score_spread":0.30468152425531575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988923285","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[2.641677e-7,0.9927125,0.00014053761,0.0004261272,0.0008023638,0.005458377,0.00033449498,0.000065658234,0.000059651276],"genre_scores_gemma":[0.00012252736,0.9938443,0.00021636407,0.00027807773,0.0011230804,0.0026600552,0.0015189103,0.00016548276,0.00007125515],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99712163,0.0002442617,0.0007681073,0.00069661957,0.0005239836,0.0006453664],"domain_scores_gemma":[0.9971069,0.0008033166,0.00043330077,0.0009968735,0.00014626075,0.000513328],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019950264,0.00077092147,0.001985108,0.00018950479,0.0002661949,0.0000301002,0.00026618692,0.00021368961,0.00020516833],"category_scores_gemma":[0.00004351947,0.00040393247,0.0017012781,0.00015949602,0.00018056227,0.000034740948,0.00002978423,0.00016286423,0.00012582714],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058503915,0.001862496,0.000007694807,0.001398056,0.023310293,0.000013010062,0.00015343388,8.101326e-7,0.0000012046278,0.00016401245,0.003117893,0.96938604],"study_design_scores_gemma":[0.0019096152,0.0019358238,0.000014108038,0.0025286854,0.002635947,0.0000060064726,0.000028739705,0.00008276385,0.000036602858,0.000047478443,0.99045235,0.00032190746],"about_ca_topic_score_codex":0.000018059602,"about_ca_topic_score_gemma":2.0998188e-7,"teacher_disagreement_score":0.98733443,"about_ca_system_score_codex":0.00021586927,"about_ca_system_score_gemma":0.00060006545,"threshold_uncertainty_score":0.9998413},"labels":[],"label_agreement":null},{"id":"W1998819602","doi":"10.1517/14728220903460340","title":"Targeting focal adhesion kinase signaling in tumor growth and metastasis","year":2009,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Focal adhesion; Cancer research; Integrin; Signal transduction; Context (archaeology); Metastasis; Extracellular matrix; Cell biology; Cancer; Biology; Cell; Biochemistry","score_opus":0.07669444610687942,"score_gpt":0.3870655295582903,"score_spread":0.3103710834514109,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998819602","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000013302203,0.99708027,0.00010646283,0.00038608385,0.0003023273,0.0017445725,0.0000126357145,0.0000988319,0.00025552712],"genre_scores_gemma":[0.00047634717,0.99579185,0.0013304588,0.0012574454,0.000452135,0.00019640222,0.00026637752,0.00016720788,0.00006177325],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.995149,0.0007783615,0.0011155359,0.0011602441,0.0009508809,0.0008459535],"domain_scores_gemma":[0.9980418,0.0005788602,0.0003183912,0.00054508913,0.00009163909,0.00042419016],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00076992344,0.0008528449,0.002379197,0.0009804718,0.00015456454,0.00007235137,0.00031137423,0.00040670412,0.00030967337],"category_scores_gemma":[0.000297295,0.00065295625,0.0005233591,0.00065223454,0.000109425324,0.00008687118,0.00014173618,0.0012402154,0.00009763348],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020159909,0.00042245828,0.0000050194026,0.0030774972,0.00013861443,0.00033424326,0.00021246621,9.789956e-7,0.0015086797,0.00014328871,0.0006010539,0.9933541],"study_design_scores_gemma":[0.001238937,0.0010200351,0.000011302023,0.011205218,0.00006821128,0.00012415153,0.00010519431,0.000110220695,0.0011668904,0.00007214225,0.98422486,0.0006528299],"about_ca_topic_score_codex":0.00003207314,"about_ca_topic_score_gemma":5.1282814e-7,"teacher_disagreement_score":0.9927013,"about_ca_system_score_codex":0.00030587148,"about_ca_system_score_gemma":0.00034782072,"threshold_uncertainty_score":0.9995922},"labels":[],"label_agreement":null},{"id":"W2001083202","doi":"10.1517/14728222.2014.948419","title":"Metabotropic glutamate receptor 5 as a potential therapeutic target in Huntington’s disease","year":2014,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"Metabotropic glutamate receptor 5; Huntington's disease; Metabotropic glutamate receptor 3; Metabotropic glutamate receptor 8; Metabotropic glutamate receptor 1; Metabotropic glutamate receptor; Glutamate receptor; Huntingtin; Metabotropic glutamate receptor 4; Metabotropic glutamate receptor 7; Neuroscience; Metabotropic glutamate receptor 6; Metabotropic receptor; Disease; Biology; Neurodegeneration; Metabotropic glutamate receptor 2; Receptor; Medicine; Genetics; Internal medicine","score_opus":0.05383114164183679,"score_gpt":0.35064254598909206,"score_spread":0.2968114043472553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001083202","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005827941,0.9901456,0.00028224193,0.00048302097,0.0059262775,0.002358705,0.00017464558,0.0002903067,0.0002808763],"genre_scores_gemma":[0.0035653852,0.98724,0.00014890074,0.005642429,0.0011660244,0.0012050307,0.00017949495,0.00038770068,0.00046502956],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99017924,0.003299979,0.0014421721,0.0025053862,0.0012296018,0.0013436103],"domain_scores_gemma":[0.9962436,0.00059206603,0.0008195726,0.0016327462,0.00008564702,0.00062635157],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.00034249568,0.001618126,0.0025213289,0.00073981436,0.00035919348,0.00029844188,0.0015787838,0.00039963028,0.0015957777],"category_scores_gemma":[0.00050012075,0.0013283489,0.0012436431,0.00078471773,0.00029022174,0.00020651313,0.00026103525,0.0008866344,0.0022373362],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036707424,0.0014178492,0.000007988902,0.0018622983,0.00016592944,0.000050667386,0.0002794421,0.00012767111,0.0042296727,0.0043660444,0.0010633842,0.986062],"study_design_scores_gemma":[0.00080252014,0.00034159728,0.000028552797,0.0017149096,0.00007769133,0.000008559376,0.00001473786,0.000115744704,0.004820124,0.0008589285,0.9899183,0.0012983398],"about_ca_topic_score_codex":0.000013994168,"about_ca_topic_score_gemma":7.5809766e-7,"teacher_disagreement_score":0.9888549,"about_ca_system_score_codex":0.0002562892,"about_ca_system_score_gemma":0.0006261363,"threshold_uncertainty_score":0.9996566},"labels":[],"label_agreement":null},{"id":"W2003118255","doi":"10.1517/14728222.2012.668185","title":"14-3-3 zeta as novel molecular target for cancer therapy","year":2012,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto; IONICS Mass Spectrometry (Canada); York University","funders":"","keywords":"Cancer; Cancer therapy; Cancer cell; Targeted therapy; Cancer research; Signal transduction; Medicine; Bioinformatics; Biology; Internal medicine; Cell biology","score_opus":0.10000229334897405,"score_gpt":0.41688283239587076,"score_spread":0.3168805390468967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003118255","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000013778917,0.9858206,0.0059628724,0.0002855653,0.0043260097,0.0025375492,0.000334923,0.00006018999,0.00067090796],"genre_scores_gemma":[0.000054072796,0.9853525,0.001767622,0.002096784,0.0024711096,0.0047371737,0.0017271745,0.0003179339,0.0014755942],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969886,0.00019881627,0.0006609165,0.0010326806,0.00033347617,0.00078549114],"domain_scores_gemma":[0.9978935,0.000083595856,0.000489779,0.001111788,0.00019345697,0.00022786668],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026002133,0.00093383004,0.0011186464,0.00017161516,0.00020685072,0.0000670097,0.0007363476,0.0008791509,0.00058877526],"category_scores_gemma":[0.0000524802,0.0007714071,0.0011025084,0.00015203704,0.00009432491,0.00001241361,0.00011449635,0.0004087572,0.0001414342],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016663178,0.00048931275,5.0271433e-7,0.00044614857,0.0013406524,9.556566e-7,0.00010128681,0.000007344764,0.013193436,0.0006764114,0.0059782043,0.9775991],"study_design_scores_gemma":[0.00072611513,0.0006339697,4.1935732e-7,0.00079757354,0.000049565486,0.0000313392,0.000014437216,0.0000038534363,0.01585855,0.00009410105,0.9809157,0.0008743741],"about_ca_topic_score_codex":0.000036707934,"about_ca_topic_score_gemma":0.0000023530022,"teacher_disagreement_score":0.97672474,"about_ca_system_score_codex":0.00013177087,"about_ca_system_score_gemma":0.0004122185,"threshold_uncertainty_score":0.9994737},"labels":[],"label_agreement":null},{"id":"W2021574933","doi":"10.1517/14728222.12.4.425","title":"Potential therapeutic targets for Parkinson's disease","year":2008,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health; BC Innovation Council","funders":"","keywords":"Dopamine; Parkinson's disease; Disease; Medicine; Substantia nigra; Dopaminergic; Neuroscience; Neuroprotection; Levodopa; Bioinformatics; Psychology; Pharmacology; Biology; Internal medicine","score_opus":0.08828067706765923,"score_gpt":0.3537629155227678,"score_spread":0.26548223845510854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021574933","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[3.8074074e-7,0.98847926,0.0018030481,0.00027291552,0.0062077995,0.0024549772,0.00020523033,0.0003310693,0.00024531534],"genre_scores_gemma":[0.0003016368,0.9921888,0.00020134037,0.0033442872,0.0020562527,0.0007533582,0.00021613472,0.00040420188,0.00053400267],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9946909,0.00068999064,0.0009290105,0.001732462,0.00084500754,0.0011126124],"domain_scores_gemma":[0.99722844,0.0006315456,0.00060064974,0.00097105285,0.00006719713,0.00050109177],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020606708,0.0011936601,0.0017851356,0.00036742084,0.0008527952,0.00018326659,0.0011229248,0.00048393203,0.00090275693],"category_scores_gemma":[0.00012064863,0.0009353141,0.0017018383,0.0003497446,0.00024147249,0.00018764604,0.00012264262,0.00064476335,0.000517515],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019818761,0.00038264712,2.446506e-7,0.0006522987,0.000108754204,0.000032746426,0.00027265676,0.000008883226,0.0001921698,0.0015875242,0.0072397925,0.9893241],"study_design_scores_gemma":[0.0006279479,0.0002951263,0.0000011486017,0.0012796541,0.000047701076,0.00004800158,0.000016420772,0.00023642072,0.00024753498,0.00054828794,0.99556744,0.0010843055],"about_ca_topic_score_codex":0.0000035344842,"about_ca_topic_score_gemma":1.4164172e-7,"teacher_disagreement_score":0.9883277,"about_ca_system_score_codex":0.00021776205,"about_ca_system_score_gemma":0.0003514196,"threshold_uncertainty_score":0.9993097},"labels":[],"label_agreement":null},{"id":"W2024420229","doi":"10.1517/14728222.11.3.307","title":"Inflammatory mediators modulating the transient receptor potential vanilloid 1 receptor: therapeutic targets to treat inflammatory and neuropathic pain","year":2007,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"TRPV1; Transient receptor potential channel; Hyperalgesia; Capsaicin; Pharmacology; Inflammation; Neuropathic pain; Nociception; Mediator; Chemistry; Receptor; Medicine; Internal medicine","score_opus":0.03983669129351819,"score_gpt":0.325767139963117,"score_spread":0.2859304486695988,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024420229","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006359489,0.9886951,0.002673453,0.00066329463,0.0031932632,0.0041850866,0.00005825814,0.00032519564,0.00014279786],"genre_scores_gemma":[0.0012716561,0.98994935,0.0006384961,0.0046194,0.0017137283,0.000747797,0.00037110172,0.00043451085,0.00025393846],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9916505,0.0026336643,0.0015997094,0.0015465195,0.0013150051,0.0012545872],"domain_scores_gemma":[0.99603415,0.0010635976,0.0006468939,0.0013037308,0.00015771671,0.0007939268],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.003542885,0.00165773,0.0023615668,0.000656654,0.00064344954,0.000112740694,0.00053671014,0.0009124808,0.00042859546],"category_scores_gemma":[0.00020482099,0.0010735525,0.00093329046,0.0004898508,0.00020826107,0.0001358633,0.00012596494,0.00125279,0.00028522863],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028834728,0.00032890768,0.000014145276,0.001548458,0.0006992199,0.00006647276,0.0024714712,0.00000659017,0.00080740964,0.00023162141,0.00089967216,0.9926377],"study_design_scores_gemma":[0.0015214183,0.001162727,0.00005964125,0.004182672,0.00026950025,0.00008594023,0.0003355038,0.00012435383,0.00020370877,0.000053809596,0.99100614,0.0009945886],"about_ca_topic_score_codex":0.000013397957,"about_ca_topic_score_gemma":0.0000022582133,"teacher_disagreement_score":0.9916431,"about_ca_system_score_codex":0.00056878553,"about_ca_system_score_gemma":0.00040353977,"threshold_uncertainty_score":0.999617},"labels":[],"label_agreement":null},{"id":"W2029679395","doi":"10.1517/14728222.2013.729042","title":"Targeting class I histone deacetylases in cancer therapy","year":2012,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"HDAC8; Histone deacetylase; Histone; Histone deacetylase 5; Epigenetics; Biology; HDAC1; Cancer research; HDAC11; Cancer; Cancer cell; Gene; Genetics","score_opus":0.10723395404369976,"score_gpt":0.4323709437233718,"score_spread":0.3251369896796721,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029679395","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000029690518,0.995861,0.000039069888,0.00013472083,0.0021920085,0.0011970245,0.00007101824,0.00004813862,0.00042735643],"genre_scores_gemma":[0.0002707099,0.99291664,0.000093008784,0.0005598647,0.0028143215,0.0012330122,0.0009572952,0.00026423225,0.0008909178],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9956777,0.00076106115,0.0008670502,0.0010791853,0.0005470666,0.0010679103],"domain_scores_gemma":[0.998287,0.00010536142,0.00037557955,0.000884426,0.00009506247,0.00025253659],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057417975,0.0008944932,0.0013380635,0.00037376035,0.00017292897,0.00004133548,0.00070376537,0.00092146295,0.00040813148],"category_scores_gemma":[0.000057881196,0.00075118645,0.00055917446,0.00034642525,0.00018319256,0.000011629436,0.00016393384,0.00077330804,0.00018881516],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011396159,0.00047872038,0.0000035735518,0.00048447071,0.00021997603,0.0000060062252,0.00024478766,0.000010749897,0.0036216143,0.000033621003,0.014606196,0.9801763],"study_design_scores_gemma":[0.0006267876,0.0002939566,0.0000017317132,0.0012772944,0.000010452222,0.000013092444,0.000031278796,0.0000072142007,0.003648339,0.0000032155235,0.99327385,0.0008128022],"about_ca_topic_score_codex":0.00012207101,"about_ca_topic_score_gemma":0.000019715348,"teacher_disagreement_score":0.9793635,"about_ca_system_score_codex":0.0005150369,"about_ca_system_score_gemma":0.00056662515,"threshold_uncertainty_score":0.9994939},"labels":[],"label_agreement":null},{"id":"W2030491415","doi":"10.1517/14728222.2011.558008","title":"Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy","year":2011,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Anaphase-promoting complex; CDC20; Cancer cell; Cell biology; Biology; Mitosis; Ubiquitin ligase; Cell cycle; Cancer research; Cancer; Cell cycle checkpoint; Ubiquitin; Anaphase; Genetics","score_opus":0.08959492628850026,"score_gpt":0.3658332928830469,"score_spread":0.27623836659454665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030491415","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000097972494,0.99634707,0.00073030265,0.000053040436,0.0007912772,0.0017771896,0.000113773865,0.00003124287,0.000058142487],"genre_scores_gemma":[0.00076813914,0.9949828,0.00014815119,0.0008723869,0.0009955522,0.0009882301,0.0011063932,0.00010978403,0.000028582479],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99821454,0.00025364253,0.0004538926,0.0005953358,0.00009768081,0.00038492982],"domain_scores_gemma":[0.99901575,0.000055822322,0.00037803312,0.00041339072,0.00006449717,0.00007250172],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030894126,0.00051276333,0.0006584515,0.00006564442,0.00037377278,0.000056207937,0.0002722437,0.00038561865,0.000027648848],"category_scores_gemma":[0.000016348833,0.00033760062,0.0003459212,0.000069438116,0.00009858334,0.0000064157125,0.000086589156,0.00023753423,0.0000027367328],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069364454,0.00012053243,0.00000767013,0.0004066198,0.00028947435,2.4091887e-7,0.00037711638,0.0000013558963,0.0049881907,0.00023936853,0.0012223871,0.9922777],"study_design_scores_gemma":[0.00049352227,0.0005566061,0.000005194813,0.0005340839,0.00002396185,0.000010172697,0.000019697045,0.00010239489,0.0011792621,0.000090988404,0.9965646,0.0004195097],"about_ca_topic_score_codex":0.000073455274,"about_ca_topic_score_gemma":0.00001179453,"teacher_disagreement_score":0.9953422,"about_ca_system_score_codex":0.000039335493,"about_ca_system_score_gemma":0.000103438826,"threshold_uncertainty_score":0.9999076},"labels":[],"label_agreement":null},{"id":"W2030592653","doi":"10.1517/14728222.2013.812074","title":"CCN2: a novel, specific and valid target for anti-fibrotic drug intervention","year":2013,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Matricellular protein; CTGF; Fibrosis; Growth factor; Connective tissue; Cancer research; Biology; Medicine; Cell biology; Immunology; Extracellular matrix; Pathology; Internal medicine; Receptor","score_opus":0.10634056850119665,"score_gpt":0.4031384518948709,"score_spread":0.29679788339367424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030592653","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000023815339,0.99061835,0.0051638433,0.00010908987,0.0010930771,0.002727326,0.00014410565,0.00003392481,0.00008645889],"genre_scores_gemma":[0.0003575508,0.9943309,0.0010555839,0.00008225342,0.00095355493,0.0010506748,0.0012557566,0.00016428344,0.0007494334],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972533,0.00028096,0.00056125975,0.0010776019,0.0002709897,0.0005558847],"domain_scores_gemma":[0.9985678,0.00015115227,0.00027998028,0.00068230723,0.0001427315,0.00017601764],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003821,0.0006376343,0.0010033448,0.00027746282,0.00015636293,0.000119329816,0.0004416808,0.0004011808,0.00025062056],"category_scores_gemma":[0.000079316604,0.00053393986,0.0005963099,0.00015657835,0.00012421119,0.000011173799,0.00020549628,0.00028267328,0.000079265126],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069719696,0.00029756755,0.0000039098236,0.0020507737,0.00046052565,9.706202e-7,0.00010608898,4.3078035e-7,0.004373421,0.0004595155,0.007879424,0.98429763],"study_design_scores_gemma":[0.00083925575,0.0006708099,0.000008729331,0.0013777679,0.000016478283,0.000021439853,0.00003929641,0.0000100420075,0.0024871435,0.00010219684,0.9938579,0.0005689384],"about_ca_topic_score_codex":0.000011797573,"about_ca_topic_score_gemma":8.828192e-7,"teacher_disagreement_score":0.9859785,"about_ca_system_score_codex":0.00008190279,"about_ca_system_score_gemma":0.0000936311,"threshold_uncertainty_score":0.9997112},"labels":[],"label_agreement":null},{"id":"W2036055666","doi":"10.1517/14728220802631876","title":"Defining protein interactions that regulate disease progression","year":2008,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Protein–protein interaction; Computational biology; Biology; Disease; Function (biology); Protein function; Cell biology; Bioinformatics; Genetics; Medicine; Gene","score_opus":0.03703699343782864,"score_gpt":0.31551305239185434,"score_spread":0.2784760589540257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036055666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5645673,0.37684307,0.012691187,0.011147921,0.0066525713,0.005959741,0.00019273821,0.00085094303,0.021094507],"genre_scores_gemma":[0.9949217,0.0013195111,0.0008121544,0.0011257335,0.00035880573,0.00030964622,0.00023989115,0.00004453397,0.0008680148],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99879026,0.00012157373,0.00016804742,0.00041503788,0.0002133253,0.00029172545],"domain_scores_gemma":[0.99926317,0.000012427346,0.000096962336,0.00041343534,0.00004338767,0.0001706456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009472327,0.00021815624,0.00012967615,0.00005421473,0.0003094316,0.000020376696,0.00017145654,0.00009224673,0.000146572],"category_scores_gemma":[0.000031267038,0.00018455034,0.000120604076,0.000060326198,0.00008693148,0.000009614082,0.000067670226,0.0001326402,0.00008327546],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020497572,0.0007941554,0.0024243973,0.000033506156,0.00016416641,0.000031028732,0.0014209998,0.000037270896,0.8333645,0.003313418,0.008789142,0.14757767],"study_design_scores_gemma":[0.00048820206,0.000298557,0.0017885125,0.000089225,0.0000013028952,0.000021180185,0.00003847314,0.000060982853,0.46817493,0.00026433985,0.528519,0.00025535192],"about_ca_topic_score_codex":0.0000034143127,"about_ca_topic_score_gemma":5.8016616e-7,"teacher_disagreement_score":0.5197298,"about_ca_system_score_codex":0.000020638861,"about_ca_system_score_gemma":0.000078647645,"threshold_uncertainty_score":0.75257444},"labels":[],"label_agreement":null},{"id":"W2038196376","doi":"10.1517/14728222.5.4.443","title":"Targeting HIV-1 integrase","year":2001,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Cegep de Saint Hyacinthe; Université de Montréal","funders":"","keywords":"Integrase; Integrase inhibitor; Reverse transcriptase; Virology; Biology; Human immunodeficiency virus (HIV); Virus; Protease; Computational biology; Enzyme; Genetics; Antiretroviral therapy; RNA; Viral load; Gene; Biochemistry","score_opus":0.031080944117598503,"score_gpt":0.3157572426580873,"score_spread":0.2846762985404888,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038196376","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04943241,0.40155703,0.030617578,0.31961328,0.015173097,0.00826702,0.000070899936,0.00454859,0.1707201],"genre_scores_gemma":[0.91784734,0.018205313,0.0075732013,0.013471331,0.0016435619,0.00029799656,0.00081803,0.00017341113,0.039969802],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984302,0.00005978091,0.00031611972,0.00040381006,0.00036110316,0.00042897186],"domain_scores_gemma":[0.9992629,0.000073901814,0.00007288855,0.00031568462,0.00006550047,0.00020912477],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00015197115,0.00030483073,0.00032603097,0.00016519445,0.00016094849,0.000024548941,0.00010880807,0.00010704276,0.0018403486],"category_scores_gemma":[0.000033927656,0.00022441524,0.00013580789,0.00020298653,0.00004979048,0.00007743461,0.000027616577,0.00020242087,0.0012766506],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003410535,0.0049397056,0.041041873,0.000055883804,0.0019769,0.00079311326,0.018921804,0.00003313109,0.018431244,0.0070628617,0.40076074,0.5025722],"study_design_scores_gemma":[0.0022909148,0.00021263104,0.001078395,0.000108611996,0.000009972754,0.00005954487,0.0007241931,0.00037150132,0.0047602965,0.000178949,0.9899277,0.00027725808],"about_ca_topic_score_codex":0.0000065316362,"about_ca_topic_score_gemma":5.5050424e-7,"teacher_disagreement_score":0.86841494,"about_ca_system_score_codex":0.00016179534,"about_ca_system_score_gemma":0.0000767363,"threshold_uncertainty_score":0.999501},"labels":[],"label_agreement":null},{"id":"W2040110061","doi":"10.1517/14728220802607363","title":"Melanoma: targeting signaling pathways and RaLP","year":2008,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Waterloo","keywords":"Melanoma; Metastatic melanoma; Medicine; Cancer research; Signal transduction; Disease; Cancer; Biology; Internal medicine; Genetics","score_opus":0.03357481669340083,"score_gpt":0.26063119984644734,"score_spread":0.2270563831530465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040110061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77718437,0.20504777,0.0065040975,0.00081890513,0.0027728158,0.00075859815,0.00004158705,0.0001984797,0.0066734077],"genre_scores_gemma":[0.9914881,0.0048229704,0.0011383742,0.0013839775,0.0007902797,0.000038111757,0.00014700978,0.000042833242,0.00014836325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986917,0.00009464957,0.00023257654,0.00046476422,0.00017280455,0.00034355294],"domain_scores_gemma":[0.99944055,0.000026963977,0.00008303772,0.00027842043,0.000038631875,0.00013240112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015440234,0.00024668287,0.0001957669,0.000050234743,0.0002862418,0.000017209104,0.00015216749,0.0001690802,0.000054583303],"category_scores_gemma":[0.000030672814,0.00021679273,0.00008844699,0.00005285101,0.000089323614,0.0000065958675,0.00006985958,0.000112212285,0.000020896758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000134637,0.00009340664,0.0008833402,0.0000072758075,0.000057205914,0.000013729557,0.0009196383,0.000010375047,0.9825877,0.00063449884,0.005985662,0.008672548],"study_design_scores_gemma":[0.0009218335,0.0007188458,0.0007365386,0.000016453141,0.0000018293571,0.00007065556,0.00024924244,0.000070027374,0.52543783,0.00017682103,0.4712193,0.00038065342],"about_ca_topic_score_codex":0.000007531785,"about_ca_topic_score_gemma":4.967098e-7,"teacher_disagreement_score":0.46523362,"about_ca_system_score_codex":0.000012248662,"about_ca_system_score_gemma":0.000049187893,"threshold_uncertainty_score":0.8840551},"labels":[],"label_agreement":null},{"id":"W2043449485","doi":"10.1517/14728222.2014.855199","title":"Targeting the type III secretion system to treat bacterial infections","year":2013,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Secretion; Type three secretion system; Virulence; Biology; Antibiotics; Mode of action; Computational biology; Microbiology; Biochemistry","score_opus":0.04880362219025401,"score_gpt":0.3625933157686126,"score_spread":0.31378969357835856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043449485","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000024166262,0.9941446,0.00026145048,0.0001547251,0.0026033933,0.0018336168,0.000025283443,0.000065784516,0.00088698335],"genre_scores_gemma":[0.00030546112,0.9939539,0.00008931232,0.00024172437,0.0027800596,0.0012829128,0.0006027038,0.000100111414,0.0006438392],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974991,0.00060308655,0.00046486358,0.0006466729,0.00029231963,0.0004939716],"domain_scores_gemma":[0.9986798,0.000104886494,0.0002086759,0.00067965337,0.00018332631,0.00014361418],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032473632,0.00053970644,0.00073975796,0.000105882886,0.0004415671,0.00010548642,0.00045836886,0.00038252008,0.000120866105],"category_scores_gemma":[0.00012633676,0.00033496844,0.00031845988,0.0002790963,0.000078367615,0.0000059684407,0.00026699837,0.00031497196,0.00027965414],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017755241,0.00024309698,0.0000027130047,0.0019246096,0.0009881858,0.0000024223928,0.0005659278,0.000019417941,0.01490533,0.00052410556,0.069821075,0.91082555],"study_design_scores_gemma":[0.00020525657,0.00070206687,0.0000013919712,0.00080897333,0.000023786943,0.00001036901,0.00014020967,0.000016894326,0.00012165209,0.0000018739175,0.99760103,0.0003664636],"about_ca_topic_score_codex":0.000049359453,"about_ca_topic_score_gemma":0.0000029533305,"teacher_disagreement_score":0.92778,"about_ca_system_score_codex":0.00016160618,"about_ca_system_score_gemma":0.00021518389,"threshold_uncertainty_score":0.99991024},"labels":[],"label_agreement":null},{"id":"W2044145734","doi":"10.1517/14728220903241625","title":"Translation initiation: a critical signalling node in cancer","year":2009,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"PI3K/AKT/mTOR pathway; EIF4E; Translation (biology); Biology; Carcinogenesis; Regulator; P70-S6 Kinase 1; Cell biology; Cancer; Signal transduction; Messenger RNA; Genetics; Gene","score_opus":0.1222404739022367,"score_gpt":0.43054058048364224,"score_spread":0.30830010658140555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044145734","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000012407974,0.9952758,0.0020966204,0.0003652026,0.0012489341,0.00049876876,0.000047992093,0.00003264449,0.0004327718],"genre_scores_gemma":[0.0007372048,0.9943555,0.0005150782,0.0016596601,0.0017120135,0.00039085787,0.0005104009,0.00009285678,0.00002644858],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975463,0.00031470752,0.00064225576,0.0007559646,0.00030691974,0.00043382242],"domain_scores_gemma":[0.9991335,0.00012777757,0.00018199247,0.000386686,0.000072416384,0.00009760071],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024922367,0.0005149429,0.0007878442,0.0001723947,0.000083661216,0.000043136646,0.00033274532,0.00067848957,0.00020224949],"category_scores_gemma":[0.000043061205,0.00047668358,0.0003531186,0.0002008956,0.0000657919,0.000008938107,0.000022783423,0.00039409194,0.000024328176],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006144564,0.00014196361,0.0000015488888,0.00045110143,0.00009178643,0.0000040801674,0.00015244025,0.000079489655,0.00089504605,0.00011234616,0.0005813462,0.9974274],"study_design_scores_gemma":[0.0003820552,0.0002734689,0.0000025932968,0.003443316,0.000023046268,0.000007833346,0.000009209019,0.000064702035,0.0008789093,0.00009908255,0.9942741,0.0005416819],"about_ca_topic_score_codex":0.0000140680595,"about_ca_topic_score_gemma":0.000007724317,"teacher_disagreement_score":0.9968857,"about_ca_system_score_codex":0.00016337885,"about_ca_system_score_gemma":0.00038120846,"threshold_uncertainty_score":0.9997685},"labels":[],"label_agreement":null},{"id":"W2060603638","doi":"10.1517/14728222.10.2.239","title":"Natriuretic peptides as therapeutic targets","year":2006,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Natriuretic peptide; Brain natriuretic peptide; NPR1; Neprilysin; NPR2; Internal medicine; Atrial natriuretic peptide; Heart failure; Medicine; Pharmacology; Endocrinology; Chemistry; Biochemistry; Enzyme","score_opus":0.06405361970051882,"score_gpt":0.3794149255980568,"score_spread":0.31536130589753797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060603638","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[1.7335724e-7,0.9795201,0.00011203516,0.0022444574,0.0021474494,0.003685796,0.00002420997,0.0004880941,0.011777701],"genre_scores_gemma":[0.00010072345,0.9831456,0.0006537601,0.0036401602,0.001645897,0.00089730724,0.0013041643,0.0003356704,0.0082767485],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99487215,0.00042040308,0.0011912857,0.0013470491,0.0010600128,0.0011091139],"domain_scores_gemma":[0.9973354,0.00031862353,0.00045501534,0.0013859106,0.00011852316,0.0003865513],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.00038239756,0.0015238378,0.0030218442,0.0007189227,0.00029047029,0.00010884951,0.00044872815,0.00077495404,0.0017224622],"category_scores_gemma":[0.00003242526,0.0010800896,0.0015449654,0.00052050577,0.00016981065,0.00011151825,0.00010979979,0.0008374092,0.003222058],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010015217,0.0008951738,0.0000033076808,0.0022283925,0.0015263595,0.00012722351,0.00027850614,5.821454e-7,0.0000047711133,0.0029703728,0.053123087,0.9387421],"study_design_scores_gemma":[0.0014548543,0.0012533864,0.000011166702,0.0048703845,0.00049944385,0.00014131458,0.00006454009,0.000008239919,0.000019020194,0.0005492162,0.9901733,0.0009551248],"about_ca_topic_score_codex":0.00006654071,"about_ca_topic_score_gemma":0.000003581304,"teacher_disagreement_score":0.93778694,"about_ca_system_score_codex":0.00060760643,"about_ca_system_score_gemma":0.0004731732,"threshold_uncertainty_score":0.99975103},"labels":[],"label_agreement":null},{"id":"W2060807298","doi":"10.1517/14728222.2014.915314","title":"Thymic stromal lymphopoietin: a central regulator of allergic asthma","year":2014,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Thymic stromal lymphopoietin; Regulator; Asthma; Immunology; Allergic asthma; Medicine; Negative regulator; Master regulator; Biology; Cell biology; Signal transduction; Genetics","score_opus":0.03727572520912862,"score_gpt":0.34708286123446097,"score_spread":0.30980713602533233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060807298","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000013488027,0.99624884,0.00007372421,0.0001387544,0.0015839974,0.0010886721,0.000057641606,0.00012267115,0.00067219033],"genre_scores_gemma":[0.0005521428,0.9957345,0.00013010898,0.0009026335,0.0016623547,0.00012782215,0.000340643,0.00017415192,0.00037561855],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964346,0.0003956802,0.0010521378,0.00076609367,0.00066758104,0.0006838504],"domain_scores_gemma":[0.9976272,0.00015630065,0.00066175987,0.0009949626,0.00009396018,0.00046580852],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018958443,0.00081659795,0.002667291,0.00029167597,0.00010429591,0.000019980711,0.00037480163,0.00057528197,0.000889943],"category_scores_gemma":[0.000040941875,0.00056744314,0.0014525192,0.00022681268,0.00020939599,0.00004446386,0.000071989176,0.0003551651,0.00017006556],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002433691,0.00054916134,0.000009853358,0.00418139,0.0005058392,0.000020232232,0.00018200843,0.000001245897,0.000017091861,0.00041679887,0.004510307,0.9893627],"study_design_scores_gemma":[0.0012654384,0.0011281497,0.00014394865,0.010005979,0.0000882592,0.00008534564,0.00005353782,0.000017520733,0.00003582753,0.000016169337,0.9866677,0.0004921142],"about_ca_topic_score_codex":0.000005729398,"about_ca_topic_score_gemma":2.8042413e-7,"teacher_disagreement_score":0.98887056,"about_ca_system_score_codex":0.0002157682,"about_ca_system_score_gemma":0.000778794,"threshold_uncertainty_score":0.9996777},"labels":[],"label_agreement":null},{"id":"W2062432510","doi":"10.1517/14728222.9.1.195","title":"B cells and autoimmunity 2004: new concepts and therapeutic perspectives","year":2005,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"University of Washington","keywords":"Autoimmunity; Immunology; Autoimmune disease; Disease; Biology; Neuroscience; Medicine; Immune system; Antibody; Pathology","score_opus":0.022210269878138063,"score_gpt":0.28691004085313465,"score_spread":0.2646997709749966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062432510","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.059945006,0.9287845,0.00032766425,0.0065480173,0.0019434887,0.0005279638,0.000018476787,0.00028289694,0.0016219681],"genre_scores_gemma":[0.9732522,0.018548125,0.0001873841,0.0027484961,0.0001904798,0.000022972734,0.000028804081,0.000042332846,0.004979215],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99813306,0.00036708193,0.0003167438,0.00056835794,0.00006000961,0.0005547138],"domain_scores_gemma":[0.9990864,0.00023985392,0.00012841976,0.0004269473,0.00005053739,0.00006785555],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018045546,0.0004058122,0.00043679797,0.00013556943,0.00043713689,0.000038978866,0.0002570214,0.00039332683,0.00157486],"category_scores_gemma":[0.000012287965,0.00033623213,0.00009097381,0.00009595912,0.0006806026,0.00011452895,0.00010050755,0.00051635166,0.00043491303],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027249206,0.00029952373,0.00006276363,0.0000041746266,0.00027637157,0.0000011601512,0.012607284,0.0000036279891,0.82018715,0.0035096828,0.003886414,0.15888937],"study_design_scores_gemma":[0.0027473774,0.00063995045,0.0010235084,0.000025628826,0.000010974898,0.0000698977,0.0031000879,0.000019371068,0.22146839,0.0006037573,0.769871,0.00042008187],"about_ca_topic_score_codex":0.00014560808,"about_ca_topic_score_gemma":0.000008636925,"teacher_disagreement_score":0.9133072,"about_ca_system_score_codex":0.000066052744,"about_ca_system_score_gemma":0.000079018064,"threshold_uncertainty_score":0.999909},"labels":[],"label_agreement":null},{"id":"W2066931715","doi":"10.1517/14728222.2014.937426","title":"Eukaryotic translation initiation factor 4E as a novel therapeutic target in hematological malignancies and beyond","year":2014,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"EIF4E; Translation (biology); Cancer research; Cancer; Biology; Eukaryotic initiation factor; Phosphorylation; EIF4A1; Function (biology); Signal transduction; Eukaryotic translation; Computational biology; Medicine; Cell biology; Messenger RNA; Gene; Genetics","score_opus":0.07200116459995802,"score_gpt":0.356964962984781,"score_spread":0.28496379838482294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066931715","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006679702,0.9937486,0.003615562,0.0002146417,0.000923322,0.0009704143,0.000070713846,0.0000473255,0.00034261262],"genre_scores_gemma":[0.01311309,0.9824474,0.0006608686,0.0019740332,0.0005057091,0.0003614541,0.00076644967,0.00012671252,0.00004428522],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99692595,0.0003987072,0.000802171,0.0009981246,0.00035867337,0.00051638327],"domain_scores_gemma":[0.9986847,0.00019522269,0.00039994798,0.00052663626,0.00006601037,0.00012747072],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032136234,0.0007512522,0.0012398562,0.00022733932,0.00011287145,0.00006656263,0.00036609115,0.0009374025,0.0001294988],"category_scores_gemma":[0.00005835655,0.0006176438,0.00034189923,0.00019642201,0.00014772807,0.000015569956,0.00006105199,0.00039646734,0.000034248],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028156769,0.0005583632,0.00007925353,0.0023699638,0.00056387024,0.000008838373,0.0010326891,0.000027024846,0.00925743,0.0018721673,0.00042154038,0.9835273],"study_design_scores_gemma":[0.00090661674,0.0007327324,0.000057014604,0.0013292336,0.00003054975,0.00008015211,0.000032346492,0.00007637734,0.0015729268,0.00042526753,0.9939519,0.00080487435],"about_ca_topic_score_codex":0.0000069868593,"about_ca_topic_score_gemma":0.0000037608927,"teacher_disagreement_score":0.9935304,"about_ca_system_score_codex":0.00009853478,"about_ca_system_score_gemma":0.00025302614,"threshold_uncertainty_score":0.9996275},"labels":[],"label_agreement":null},{"id":"W2068057735","doi":"10.1517/14728222.10.4.515","title":"Targeting the dopamine D<sub>2</sub>receptor in schizophrenia","year":2006,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":302,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"","keywords":"Dopamine receptor D2; Antipsychotic; Dopamine; Haloperidol; Psychosis; Schizophrenia (object-oriented programming); Parkinsonism; Pharmacology; Dopamine receptor; Typical antipsychotic; Dopamine hypothesis of schizophrenia; Medicine; Dopamine receptor D3; Neuroscience; Psychology; Internal medicine; Psychiatry; Atypical antipsychotic; Disease","score_opus":0.06421932111572513,"score_gpt":0.34081017605572345,"score_spread":0.2765908549399983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068057735","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014430536,0.9917298,0.000041749485,0.00035957058,0.0043509062,0.0027928287,0.000108100714,0.0003239649,0.00014877829],"genre_scores_gemma":[0.00053558615,0.9944509,0.00007219305,0.0019475694,0.001055845,0.0014243406,0.00011400002,0.00033805353,0.00006149583],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9924277,0.0016811625,0.0016213981,0.00189032,0.0011206159,0.0012588135],"domain_scores_gemma":[0.99672425,0.0010258564,0.00074513815,0.0012673913,0.00004501406,0.00019232632],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0005371621,0.0014152637,0.0018514522,0.0006051967,0.00042063903,0.00024519986,0.0019721722,0.00054869393,0.00026261256],"category_scores_gemma":[0.00015783252,0.0009666468,0.0007846027,0.0012372977,0.00038609214,0.00028716095,0.00017513562,0.0018847167,0.0016493351],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058120557,0.00036126463,0.0000018132251,0.00038489085,0.000015791788,0.000029619232,0.00017040818,0.0000096168205,0.03957274,0.00025278676,0.002419316,0.95672363],"study_design_scores_gemma":[0.0006561713,0.00015162738,0.000004705369,0.002348195,0.000018068595,0.00004160989,0.000012264808,0.000013381522,0.029510127,0.000036524085,0.96620244,0.0010048843],"about_ca_topic_score_codex":0.000019758525,"about_ca_topic_score_gemma":0.0000023367097,"teacher_disagreement_score":0.96378314,"about_ca_system_score_codex":0.00036476206,"about_ca_system_score_gemma":0.00024962323,"threshold_uncertainty_score":0.99985975},"labels":[],"label_agreement":null},{"id":"W2071096373","doi":"10.1517/14728222.8.6.527","title":"Therapeutic targets for antimetastatic therapy","year":2004,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Metastasis; Medicine; Cancer; Cancer metastasis; Cancer cell; Cancer therapy; Oncology; Cancer research; Internal medicine","score_opus":0.1280737700992592,"score_gpt":0.41636560468693457,"score_spread":0.2882918345876754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071096373","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[1.1899923e-7,0.9851521,0.0033120664,0.0006360311,0.0038386192,0.0059930948,0.00024723113,0.00026435606,0.00055637496],"genre_scores_gemma":[0.000022285227,0.9866845,0.002728491,0.004420926,0.0014967485,0.0018523021,0.0013760795,0.00049891014,0.0009197645],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948528,0.00030017056,0.0013618709,0.0014707873,0.0008229332,0.0011914412],"domain_scores_gemma":[0.9967156,0.00048925553,0.0007289637,0.0014154627,0.00020587775,0.0004448088],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0005600303,0.0015460964,0.0040031713,0.00060257234,0.00030487,0.0001012343,0.00054770446,0.0006368759,0.0014051456],"category_scores_gemma":[0.00003713287,0.0010971777,0.0024459846,0.0005483475,0.00018968731,0.0001127512,0.000053677093,0.00075270445,0.00031977848],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044712579,0.00088928244,2.702241e-7,0.0052839876,0.0021932065,0.000016217165,0.000516946,0.0000024058131,0.000037878326,0.00095290743,0.0033994627,0.9862603],"study_design_scores_gemma":[0.004148532,0.001979082,0.0000018239992,0.008119774,0.00038421623,0.000115437986,0.00006572915,0.000009410957,0.00027072214,0.00059367146,0.9832426,0.001069016],"about_ca_topic_score_codex":0.000028449342,"about_ca_topic_score_gemma":0.0000011903796,"teacher_disagreement_score":0.9851913,"about_ca_system_score_codex":0.0006235861,"about_ca_system_score_gemma":0.0013360559,"threshold_uncertainty_score":0.99972874},"labels":[],"label_agreement":null},{"id":"W2085456770","doi":"10.1517/14728222.11.8.993","title":"Cathelicidins and functional analogues as antisepsis molecules","year":2007,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":111,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Health Canada; Genome British Columbia; Foundation for the National Institutes of Health","keywords":"Cathelicidin; Antimicrobial; Innate immune system; Antimicrobial peptides; Biology; Pathogen; Limiting; Immune system; Sepsis; Antibiotics; Microbiology; Immunology","score_opus":0.08206612277757039,"score_gpt":0.349240141007834,"score_spread":0.26717401823026365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085456770","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000046832824,0.9957232,0.00025464458,0.000105943946,0.0021694812,0.0003791094,0.00011385294,0.000108230466,0.0011408706],"genre_scores_gemma":[0.00017620389,0.9954735,0.000057126315,0.0011853195,0.00028262337,0.000042516236,0.0011097341,0.000077179764,0.0015957938],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99812317,0.00022936657,0.00046773007,0.0006206886,0.00006994892,0.0004890895],"domain_scores_gemma":[0.99900866,0.0003089827,0.00026586332,0.0003296082,0.000042157244,0.000044744666],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017648799,0.0006077299,0.0011840999,0.00031539318,0.0003330498,0.00004182793,0.00019794093,0.00069643994,0.00090189115],"category_scores_gemma":[0.00001845914,0.00046402795,0.00042669135,0.00013308293,0.00033637084,0.00007466113,0.000091006776,0.00051753735,0.00090558873],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057612768,0.00016251637,0.0000012622114,0.00030778386,0.0006961318,0.000005851828,0.00027977128,2.1187844e-7,0.0007396309,0.0030692592,0.01020743,0.9844725],"study_design_scores_gemma":[0.0002953551,0.00024864942,0.000012816355,0.0014478326,0.00004683223,0.00020574224,0.00013306394,2.2176509e-7,0.0009418734,0.00010636336,0.9960606,0.0005006284],"about_ca_topic_score_codex":0.000081744234,"about_ca_topic_score_gemma":0.000003231086,"teacher_disagreement_score":0.9858532,"about_ca_system_score_codex":0.00006417751,"about_ca_system_score_gemma":0.00011475119,"threshold_uncertainty_score":0.9998723},"labels":[],"label_agreement":null},{"id":"W2098564211","doi":"10.1517/14728222.2012.680955","title":"Targeting pain mediators induced by injured nerve-derived COX2 and PGE2 to treat neuropathic pain","year":2012,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Medicine; Neuropathic pain; Nerve injury; Hyperalgesia; Allodynia; Neurotrophin; Neuroscience; Population; Dorsal root ganglion; Neurotrophic factors; Nerve growth factor; Chronic pain; Peripheral nerve injury; Sensory system; Nociception; Anesthesia; Bioinformatics; Internal medicine; Sciatic nerve; Psychology; Biology; Physical therapy; Receptor","score_opus":0.06349108897793913,"score_gpt":0.3476302048239426,"score_spread":0.28413911584600343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098564211","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000032876655,0.9944828,0.0010214804,0.00051273755,0.0011891806,0.0024138729,0.00006246086,0.00022904274,0.000055554807],"genre_scores_gemma":[0.0018830199,0.98940086,0.00053048827,0.005154651,0.0008693121,0.0007414973,0.0009848006,0.00030958265,0.00012578644],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99235904,0.004055344,0.0009248172,0.0010773478,0.0006384717,0.0009450028],"domain_scores_gemma":[0.99676925,0.0011503579,0.00043777155,0.0007189124,0.0000732031,0.00085051236],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0035400027,0.0011946582,0.0023541134,0.0003783089,0.0002587566,0.000060770064,0.00027125943,0.0007284906,0.0002181043],"category_scores_gemma":[0.0005439275,0.0008743225,0.0004251311,0.00037005692,0.000054452605,0.00009103209,0.00010407083,0.0006990908,0.00013245601],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009661786,0.0004518345,0.000013739282,0.0013378875,0.00032445125,0.000030669744,0.0008780419,4.1389974e-8,0.0017983414,0.000039267634,0.0023094113,0.9927197],"study_design_scores_gemma":[0.0012236896,0.0016481617,0.000013646994,0.0037252137,0.00020977025,0.000023771612,0.00012624374,0.000032631022,0.0002720268,0.000023117947,0.99190456,0.00079714356],"about_ca_topic_score_codex":0.000045024488,"about_ca_topic_score_gemma":5.7940696e-7,"teacher_disagreement_score":0.99192256,"about_ca_system_score_codex":0.00027853175,"about_ca_system_score_gemma":0.00017681497,"threshold_uncertainty_score":0.99937075},"labels":[],"label_agreement":null},{"id":"W2098564856","doi":"10.1517/14728222.6.2.159","title":"Tissue factor – a therapeutic target for thrombotic disorders","year":2002,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Tissue factor; Thromboplastin; Coagulation; Pharmacology; Factor X; Protein C; Cancer research; Immunology; Tissue factor pathway inhibitor; Medicine; Chemistry; Thrombin; Biochemistry; Platelet; Internal medicine","score_opus":0.12248357375745646,"score_gpt":0.39606834235928234,"score_spread":0.2735847686018259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098564856","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[9.252923e-8,0.98030335,0.00866801,0.00094292103,0.003664713,0.005019276,0.00012078691,0.00038683217,0.00089404045],"genre_scores_gemma":[0.00022463636,0.9910352,0.0016899932,0.0023879204,0.0010557628,0.0012387886,0.0007185696,0.0004098932,0.0012392133],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9958154,0.0002943896,0.001074952,0.0012117494,0.0007007907,0.00090273214],"domain_scores_gemma":[0.9973813,0.0004337157,0.00054403034,0.0011628565,0.00011226401,0.00036581865],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020405972,0.0012550494,0.0031430055,0.00047040317,0.00030094341,0.00008192798,0.00046160482,0.00091691746,0.00334393],"category_scores_gemma":[0.000042552598,0.00095718127,0.0012924022,0.00041569804,0.000115128525,0.000104928135,0.000056104425,0.0006319912,0.0006205972],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000414721,0.00081285305,7.100791e-7,0.0023277423,0.001091247,0.0000019687197,0.00041799623,6.8511963e-7,0.00003102686,0.003762732,0.0018693014,0.98964226],"study_design_scores_gemma":[0.0017541784,0.0020309207,0.000009230876,0.0035424111,0.0002689301,0.000031194682,0.00004789756,0.00010673421,0.00012693761,0.001470741,0.9896504,0.00096041034],"about_ca_topic_score_codex":0.000005579307,"about_ca_topic_score_gemma":0.0000011418393,"teacher_disagreement_score":0.98868185,"about_ca_system_score_codex":0.00026247662,"about_ca_system_score_gemma":0.00023367908,"threshold_uncertainty_score":0.99928784},"labels":[],"label_agreement":null},{"id":"W2101090893","doi":"10.1517/14728222.2015.1042365","title":"Subcellular G-protein coupled receptor signaling hints at greater therapeutic selectivity","year":2015,"lang":"en","type":"editorial","venue":"Expert Opinion on Therapeutic Targets","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; McGill University; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Receptor; Subcellular localization; Cell biology; Signal transduction; Nucleus; Biology; Extracellular; Rhodopsin-like receptors; Cell surface receptor; Intracrine; Transmembrane protein; Cell; Functional selectivity; Cytoplasm; Biochemistry; Agonist; Paracrine signalling","score_opus":0.02336361581227873,"score_gpt":0.2816742498174154,"score_spread":0.25831063400513665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101090893","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007897659,0.116017565,0.0056083356,0.0003076436,0.8671836,0.002075878,0.00029090594,0.00025396256,0.0003644267],"genre_scores_gemma":[0.10638291,0.0064073936,0.0010584153,0.0011974137,0.8654822,0.0007569482,0.008941497,0.0008757437,0.008897463],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99471444,0.00059241295,0.00068985374,0.0016682775,0.0013666514,0.0009683361],"domain_scores_gemma":[0.997396,0.00010856681,0.0004970885,0.0010886517,0.00056111434,0.00034857442],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010614316,0.0011054069,0.00091446843,0.00016473098,0.0003958434,0.00013442483,0.00077344995,0.0020965163,0.0013366783],"category_scores_gemma":[0.00016571947,0.0009755999,0.00048410805,0.00016247007,0.00012192555,0.000013905464,0.00024451088,0.0008288007,0.00027536636],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009656839,0.00013737177,0.0000038461535,0.000027060765,0.00038842205,0.0000038699286,0.00028636723,0.000032893116,0.6712415,0.000019721176,0.32468292,0.0022102904],"study_design_scores_gemma":[0.0010084447,0.00092235167,5.8607293e-7,0.00009198739,0.000011840141,0.000002144752,0.00003756381,0.000101947146,0.38777202,0.00013227662,0.6091661,0.0007527467],"about_ca_topic_score_codex":0.00006124797,"about_ca_topic_score_gemma":0.0000065066843,"teacher_disagreement_score":0.28448316,"about_ca_system_score_codex":0.0004342368,"about_ca_system_score_gemma":0.00047689132,"threshold_uncertainty_score":0.9995762},"labels":[],"label_agreement":null},{"id":"W2103071544","doi":"10.1517/14728222.2012.718331","title":"Targeting IL-1 in depression","year":2012,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":162,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Neuroinflammation; Depression (economics); Antidepressant; Anakinra; Inflammation; Medicine; Interleukin; Neurogenesis; Receptor antagonist; Interleukin 6; Cytokine; Internal medicine; Immunology; Pharmacology; Receptor; Antagonist; Psychology; Neuroscience; Hippocampus; Disease","score_opus":0.11416306333005723,"score_gpt":0.37276939465907355,"score_spread":0.25860633132901634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103071544","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[5.967589e-7,0.9942522,0.000066920344,0.000055585322,0.0028310334,0.0008863178,0.000022815844,0.00017609981,0.001708439],"genre_scores_gemma":[0.00034481124,0.996892,0.000082911,0.0014387048,0.0006298845,0.0002717661,0.00006124342,0.00014138264,0.00013734387],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963116,0.0007137262,0.0007082462,0.00094805675,0.00048051836,0.00083783764],"domain_scores_gemma":[0.9982703,0.00061790645,0.000354179,0.00057520805,0.0000121614685,0.0001702432],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029076167,0.0006964881,0.0011295194,0.00039870452,0.00017141529,0.00006206387,0.0007180821,0.00047115004,0.00057292136],"category_scores_gemma":[0.00015127797,0.0005256398,0.00048490256,0.0004814055,0.000093418705,0.00019157944,0.00013843707,0.000719331,0.00075980613],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017714912,0.00025480214,0.0000015588469,0.00048217934,0.000012748041,0.00000622107,0.00042243543,0.0000016160841,0.0002733775,0.0004518106,0.0011012527,0.9969743],"study_design_scores_gemma":[0.0003380626,0.00004825583,0.0000036389135,0.0022283075,0.0000051185393,0.00001586372,0.000037308713,0.000014881899,0.00043696165,0.00010728725,0.996164,0.000600273],"about_ca_topic_score_codex":0.000007344907,"about_ca_topic_score_gemma":5.5603095e-7,"teacher_disagreement_score":0.996374,"about_ca_system_score_codex":0.0001502005,"about_ca_system_score_gemma":0.0000958155,"threshold_uncertainty_score":0.9997195},"labels":[],"label_agreement":null},{"id":"W2104370773","doi":"10.1517/14728222.2011.561787","title":"Hax-1: a regulator of calcium signaling and apoptosis progression with multiple roles in human disease","year":2011,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Cell biology; Endoplasmic reticulum; Apoptosis; Biology; Inhibitor of apoptosis domain; Calcium signaling; Inhibitor of apoptosis; Signal transduction; Programmed cell death; Caspase; Biochemistry","score_opus":0.043535953456739544,"score_gpt":0.3438346234480893,"score_spread":0.30029866999134974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2104370773","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008691718,0.9982261,0.000047292157,0.000012092055,0.00007197703,0.00069984276,0.00003200197,0.00000979727,0.00003171978],"genre_scores_gemma":[0.061045345,0.9378072,0.00021329906,0.00004353227,0.000073323085,0.00028758097,0.00044361522,0.00006279829,0.000023317005],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99866486,0.00014714687,0.00032019673,0.00051468116,0.00012767434,0.0002254673],"domain_scores_gemma":[0.9992457,0.0000147505425,0.00023280934,0.00036703734,0.000027745662,0.0001119784],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000078887955,0.00038174624,0.0006220079,0.00009657667,0.0000675247,0.000012047262,0.00014353773,0.00022589577,0.000011812996],"category_scores_gemma":[0.0000062905237,0.00025845124,0.0001552179,0.000065087086,0.00008984074,0.000003955587,0.000059384638,0.00009475206,0.0000010142027],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029593048,0.001093067,0.0008679753,0.0011444787,0.00044870022,0.000002753671,0.00021728409,0.0000011953762,0.0009892298,0.00007975756,0.00005900517,0.9948006],"study_design_scores_gemma":[0.0024996707,0.0014974247,0.0002607209,0.008098749,0.0001169454,0.00000464179,0.000072616174,0.0000057168077,0.01575052,0.00006885001,0.9708703,0.00075384096],"about_ca_topic_score_codex":0.000021258742,"about_ca_topic_score_gemma":0.000005051341,"teacher_disagreement_score":0.9940468,"about_ca_system_score_codex":0.000014607209,"about_ca_system_score_gemma":0.00007683453,"threshold_uncertainty_score":0.99998677},"labels":[],"label_agreement":null},{"id":"W2106019293","doi":"10.1517/14728222.2012.665879","title":"Targeting frameshifting in the human immunodeficiency virus","year":2012,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Frameshift mutation; Translational frameshift; Ribosome; Biology; Cell biology; Genetics; RNA; Gene; Mutation","score_opus":0.07128626624621855,"score_gpt":0.3606875577794025,"score_spread":0.28940129153318395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106019293","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000007979096,0.9969329,0.00038012976,0.000049235845,0.0009311571,0.00083786045,0.000013861105,0.000023135643,0.00082369347],"genre_scores_gemma":[0.0016538909,0.99535257,0.00020075163,0.0007176037,0.0011061933,0.00044150406,0.00035631302,0.000105453655,0.00006569762],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968944,0.0008768147,0.0006617203,0.0006051934,0.00032930454,0.00063255074],"domain_scores_gemma":[0.99861723,0.00010309879,0.00037390937,0.00082259404,0.000025930489,0.000057209312],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011685771,0.0005812697,0.00074090774,0.00011989453,0.0003062892,0.000071262046,0.0009528476,0.00060193933,0.0001397838],"category_scores_gemma":[0.000050328177,0.00038162962,0.00042081712,0.00017459191,0.00006235415,0.0000067467636,0.000119675184,0.00045280403,0.00009472895],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010404361,0.00020685462,0.0000014517185,0.0002918634,0.00008241193,0.0000020767923,0.0006220807,0.0000010996379,0.012203879,0.0009225583,0.00028250576,0.98537284],"study_design_scores_gemma":[0.00012885102,0.00016263334,0.00000214651,0.000791995,0.000015827167,0.00001236539,0.00014149015,9.45647e-7,0.0014919513,0.00010154363,0.9966685,0.0004817398],"about_ca_topic_score_codex":0.000023889146,"about_ca_topic_score_gemma":0.0000011148286,"teacher_disagreement_score":0.996386,"about_ca_system_score_codex":0.00004320916,"about_ca_system_score_gemma":0.00007577334,"threshold_uncertainty_score":0.99986356},"labels":[],"label_agreement":null},{"id":"W2107857520","doi":"10.1517/14728222.11.2.161","title":"Targeting acetylcholinesterase to treat neurodegeneration","year":2007,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":213,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Acetylcholinesterase; Acetylcholine; Cholinergic; Neurodegeneration; Pharmacology; Alzheimer's disease; Disease; Medicine; Neuroscience; Aché; Cholinesterase; Muscarinic acetylcholine receptor; Chemistry; Internal medicine; Biology; Biochemistry; Enzyme; Receptor","score_opus":0.15642265201261588,"score_gpt":0.4447747027527863,"score_spread":0.28835205074017045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107857520","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000040223455,0.9939005,0.0006171811,0.0004305675,0.0020445597,0.0023303025,0.000095313015,0.0002494286,0.0002919465],"genre_scores_gemma":[0.000051751795,0.9779933,0.0003804945,0.01347861,0.0045753038,0.000400281,0.0021005124,0.00027965513,0.0007400651],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9958119,0.00034907437,0.0011419002,0.0013236353,0.0006584373,0.0007150898],"domain_scores_gemma":[0.99758345,0.0002911542,0.00030820747,0.00094722916,0.00020480456,0.0006651795],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025054265,0.0011301045,0.0020343284,0.00072679174,0.00024118446,0.00010626027,0.00028043092,0.00041590788,0.00029059307],"category_scores_gemma":[0.0001431252,0.0008541618,0.0008285982,0.0006344094,0.000048707265,0.00012618485,0.000082001,0.00058670575,0.0005958735],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030311296,0.0006064809,0.0000027000576,0.0014933664,0.00012277541,0.00010037396,0.00030604514,0.000013872786,0.0008404651,0.00006645099,0.014494842,0.9816495],"study_design_scores_gemma":[0.00090182276,0.0004730689,0.000005059025,0.0035175416,0.00012975189,0.00010595381,0.000021039052,0.000018230476,0.0011793245,0.0000018577056,0.99291396,0.00073239784],"about_ca_topic_score_codex":0.00000601027,"about_ca_topic_score_gemma":6.151875e-7,"teacher_disagreement_score":0.9809171,"about_ca_system_score_codex":0.00023408694,"about_ca_system_score_gemma":0.0003009486,"threshold_uncertainty_score":0.9993909},"labels":[],"label_agreement":null},{"id":"W2112130045","doi":"10.1517/14728222.12.2.209","title":"Mammalian target of rapamycin as a therapeutic target in oncology","year":2008,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Pearl; Oncology; Clinical Oncology; Internal medicine; Medicine; Geography; Cancer; Archaeology","score_opus":0.05541256095740467,"score_gpt":0.38230976146342105,"score_spread":0.3268972005060164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112130045","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000143685265,0.9942937,0.00030806055,0.00019412696,0.0023387766,0.0013021372,0.000086507294,0.000043394353,0.001418949],"genre_scores_gemma":[0.00096437335,0.99340194,0.0009658866,0.0016317603,0.0010861855,0.0005828414,0.000682373,0.00025570253,0.00042891293],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99462265,0.0011167341,0.0014331912,0.0013746094,0.00055103406,0.0009017869],"domain_scores_gemma":[0.9971623,0.00025547878,0.0009001602,0.001328694,0.00013850466,0.00021488553],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005124085,0.0011031156,0.0023610336,0.00046509702,0.00011215653,0.000021425174,0.0011367786,0.0015355268,0.00056438486],"category_scores_gemma":[0.00010391084,0.0009598984,0.0009795654,0.00045055366,0.00032530518,0.000011923192,0.00018482935,0.00075484096,0.00012393377],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065766834,0.0009918368,0.0000370663,0.0011987119,0.0010060782,0.000054606026,0.0008207671,0.000053799376,0.0048207473,0.000251249,0.0076526823,0.9824548],"study_design_scores_gemma":[0.00097196636,0.0021688659,0.00000844692,0.0020803863,0.000025354755,0.00013084518,0.000054540473,0.000007918206,0.0061409688,0.00018686512,0.98730105,0.00092280004],"about_ca_topic_score_codex":0.000051692346,"about_ca_topic_score_gemma":0.0000064894502,"teacher_disagreement_score":0.981532,"about_ca_system_score_codex":0.00036671472,"about_ca_system_score_gemma":0.0015488098,"threshold_uncertainty_score":0.9997607},"labels":[],"label_agreement":null},{"id":"W2115365563","doi":"10.1517/14728222.7.2.249","title":"When the DREAM is gone:from basic science to future prospectives in pain management and beyond","year":2003,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Dynorphin; Dream; Transcription factor; Repressor; Neuroscience; Biology; Cell biology; Gene; Opioid peptide; Opioid; Genetics; Receptor","score_opus":0.037462084973372646,"score_gpt":0.34152721449809936,"score_spread":0.3040651295247267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115365563","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000027368053,0.9927141,0.00030699203,0.0016666354,0.0008012941,0.0028385597,0.000021823285,0.000035289715,0.0016125791],"genre_scores_gemma":[0.000058381418,0.98784536,0.0021395523,0.008298938,0.0002801436,0.0006849031,0.00004215236,0.000059919937,0.00059063616],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973634,0.00031877862,0.00037693183,0.0009354253,0.0005482565,0.00045721364],"domain_scores_gemma":[0.9987833,0.00012208689,0.00013721104,0.0007347189,0.000036728543,0.00018593534],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009099008,0.00052857026,0.00093385385,0.0003267599,0.00022051261,0.000085272266,0.00031190988,0.00017224677,0.00021840713],"category_scores_gemma":[0.000015142709,0.0003056454,0.00016737031,0.0004767786,0.00011943469,0.00007779911,0.00009082727,0.00030389818,0.000080145444],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031834716,0.00029464316,0.000013781047,0.0003633359,0.00025181408,0.000020718151,0.0033215724,6.042168e-8,0.00000397017,0.0029219757,0.0015491219,0.99122715],"study_design_scores_gemma":[0.0006751933,0.00040599474,0.00022057304,0.0032855384,0.00005685409,0.000010658381,0.00082587404,0.000007390444,0.000017905384,0.0018104672,0.9923874,0.00029613925],"about_ca_topic_score_codex":0.000020710024,"about_ca_topic_score_gemma":0.000001891721,"teacher_disagreement_score":0.99093103,"about_ca_system_score_codex":0.0003656344,"about_ca_system_score_gemma":0.0001594733,"threshold_uncertainty_score":0.99993956},"labels":[],"label_agreement":null},{"id":"W2116344367","doi":"10.1517/14728222.2010.531014","title":"Paving the way for targeting RSK in cancer","year":2010,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Kinase; Ribosomal s6 kinase; MAPK/ERK pathway; Biology; Cell biology; Motility; Cancer cell; Cancer; Signal transduction; Phosphorylation; Cell growth; Protein kinase A; p38 mitogen-activated protein kinases; Cancer research; PI3K/AKT/mTOR pathway; Biochemistry; Genetics; P70-S6 Kinase 1","score_opus":0.02663451962857396,"score_gpt":0.31911428966363176,"score_spread":0.2924797700350578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2116344367","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7903795,0.1475563,0.010778699,0.017059185,0.025246257,0.003969853,0.0001523076,0.00017086716,0.0046870303],"genre_scores_gemma":[0.99356616,0.0012660199,0.000587161,0.0024965764,0.0013791336,0.0003649911,0.00008269601,0.00003515526,0.00022211368],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990655,0.000047862726,0.00017951673,0.00030779807,0.00009907208,0.0003002588],"domain_scores_gemma":[0.99951065,0.000045470246,0.00006432106,0.00029246125,0.00003894694,0.00004813944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026972764,0.00015683864,0.000116907526,0.000030113313,0.00014109797,0.000021201666,0.0002340099,0.0001439459,0.000078597994],"category_scores_gemma":[0.00005306832,0.00010788847,0.00008504595,0.000047668746,0.00004452095,0.0000035896499,0.00004032567,0.00015733554,0.0000067273863],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009646661,0.00006637235,0.0006323371,0.0000054107636,0.00002350761,4.0875702e-7,0.00044147242,0.000016688642,0.95139897,0.0012879703,0.0048597953,0.041170575],"study_design_scores_gemma":[0.00048946775,0.00016218012,0.0010388354,0.000010065623,9.0665515e-7,0.0000017175038,0.00013588546,0.00021669087,0.24839783,0.00022465039,0.74916214,0.00015960685],"about_ca_topic_score_codex":0.000043221367,"about_ca_topic_score_gemma":0.00006764598,"teacher_disagreement_score":0.7443024,"about_ca_system_score_codex":0.0000107937585,"about_ca_system_score_gemma":0.000045817666,"threshold_uncertainty_score":0.43995643},"labels":[],"label_agreement":null},{"id":"W2118534575","doi":"10.1517/14728222.12.1.59","title":"Targeting synuclein-γ to counteract drug resistance in cancer","year":2007,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Synuclein; Medicine; Cancer research; Breast cancer; Cancer; Internal medicine; Oncology; Disease; Alpha-synuclein; Parkinson's disease","score_opus":0.07792850072708807,"score_gpt":0.41458467241393715,"score_spread":0.3366561716868491,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118534575","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000005660504,0.99434245,0.00006656314,0.00046797027,0.0019534295,0.0019276001,0.00009250559,0.00010825187,0.0010355705],"genre_scores_gemma":[0.00019403132,0.9925728,0.0007710996,0.003254211,0.0006602837,0.0007441395,0.00029338186,0.00019068111,0.0013193901],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965308,0.00018038506,0.00084681873,0.001023996,0.0006513698,0.0007666671],"domain_scores_gemma":[0.99836344,0.00019522049,0.0003151769,0.0006348312,0.000081826416,0.00040949727],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036348996,0.0008105224,0.0019133608,0.0005626102,0.00012199908,0.000042601536,0.00028045563,0.00029033615,0.00062883634],"category_scores_gemma":[0.000039098304,0.00062962633,0.00046822077,0.0005121538,0.000030211108,0.00007196876,0.000058606474,0.00050362013,0.00038252832],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043544403,0.0008356067,0.000017489643,0.002120181,0.0005285931,0.000273169,0.0008303298,0.0000013335386,0.000010918544,0.00027849874,0.01015415,0.9845143],"study_design_scores_gemma":[0.0009200107,0.00011488077,0.000042186253,0.019282054,0.000072439994,0.000007637839,0.00004516876,0.000005238971,0.00002362748,0.00003568801,0.9789173,0.0005337424],"about_ca_topic_score_codex":0.00008712027,"about_ca_topic_score_gemma":0.000031471922,"teacher_disagreement_score":0.98398054,"about_ca_system_score_codex":0.0011681287,"about_ca_system_score_gemma":0.00038597526,"threshold_uncertainty_score":0.9996155},"labels":[],"label_agreement":null},{"id":"W2120485507","doi":"10.1517/14728222.2014.915315","title":"Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer","year":2014,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Triple-negative breast cancer; Breast cancer; Medicine; Cancer; Cancer research; Carcinogenesis; Targeted therapy; Bioinformatics; Oncology; Internal medicine; Biology","score_opus":0.028072617608273696,"score_gpt":0.33658227045227634,"score_spread":0.30850965284400267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120485507","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000026184283,0.99780655,0.00018554727,0.00019622369,0.00088909455,0.0006705573,0.0001191263,0.000028413328,0.00007832865],"genre_scores_gemma":[0.0009876199,0.9945748,0.00028425164,0.00056764274,0.0023170852,0.0003008489,0.00065997784,0.00012451224,0.00018330065],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971648,0.00040949185,0.0007336319,0.00093833386,0.00023598899,0.00051776733],"domain_scores_gemma":[0.9988542,0.00013391873,0.00042791668,0.00036003508,0.0000764502,0.00014744127],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033534446,0.00071213744,0.0012074782,0.00019539514,0.00013825219,0.00005177945,0.00031701097,0.00058176776,0.00026435187],"category_scores_gemma":[0.000055520057,0.0005762329,0.00028032818,0.00021721536,0.00009735202,0.000009216507,0.00011773993,0.00042606285,0.000019704865],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002460481,0.00021273167,0.000040203253,0.0013517982,0.00052501686,0.000005613943,0.00043761876,0.00007013656,0.002611834,0.00007478022,0.019406442,0.9750178],"study_design_scores_gemma":[0.00081209146,0.00021136888,0.0000054243105,0.0036475137,0.000028049499,0.000026883898,0.00008534523,0.000026832724,0.0007960783,0.000017661252,0.99362475,0.0007180147],"about_ca_topic_score_codex":0.000097581484,"about_ca_topic_score_gemma":0.000002168075,"teacher_disagreement_score":0.9742998,"about_ca_system_score_codex":0.00008145394,"about_ca_system_score_gemma":0.00018063058,"threshold_uncertainty_score":0.9996689},"labels":[],"label_agreement":null},{"id":"W2121138686","doi":"10.1517/14728220903454988","title":"<i>Pseudomonas aeruginosa</i>biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies","year":2010,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Pseudomonas aeruginosa; Cystic fibrosis; Biofilm; Microbiology; Mucus; Airway; Antibiotics; Immune system; Immunology; Organism; Biology; Medicine; Bacteria; Internal medicine","score_opus":0.039603045164154124,"score_gpt":0.3693162186729152,"score_spread":0.32971317350876106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121138686","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000633373,0.9959449,0.00009000833,0.0001578004,0.00070334936,0.0025751365,0.000040793315,0.00016180862,0.0002628753],"genre_scores_gemma":[0.0012967641,0.99336267,0.0011795759,0.00010790662,0.0005128268,0.002865433,0.00044091398,0.00013497897,0.00009891234],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99648404,0.00031459768,0.0008792027,0.0010867041,0.0005644116,0.00067103415],"domain_scores_gemma":[0.9974797,0.0009521394,0.00029671603,0.00076073525,0.00014893195,0.00036178314],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016027871,0.0009786711,0.0020613587,0.0007843671,0.00024030758,0.00015952002,0.00024388033,0.0005920355,0.00011425689],"category_scores_gemma":[0.00021848636,0.0006739159,0.00033521437,0.00077632105,0.00032223816,0.00026958622,0.00008400307,0.0008636565,0.00008338402],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015862474,0.0009731235,0.000016833581,0.0053696004,0.00024265544,0.000041381158,0.0015019799,0.0000017028354,0.0006806159,0.00033272622,0.000071472954,0.9906093],"study_design_scores_gemma":[0.0013343714,0.0026029942,0.00003837224,0.010108842,0.00008662654,0.00018267674,0.00028211923,0.000011888301,0.00018461524,0.00049919845,0.9840815,0.0005867993],"about_ca_topic_score_codex":0.00012696888,"about_ca_topic_score_gemma":0.00019544162,"teacher_disagreement_score":0.9900225,"about_ca_system_score_codex":0.00050168566,"about_ca_system_score_gemma":0.0018210132,"threshold_uncertainty_score":0.9995712},"labels":[],"label_agreement":null},{"id":"W2122998269","doi":"10.1517/14728222.11.6.733","title":"The role of vasoactive intestinal peptide in neuroprotection: interview with Professor Illana Gozes","year":2007,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Anesthesia and Neurotoxicity Research","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Editorial board; Library science; Editor in chief; Tel aviv; Management; Medicine","score_opus":0.05300640129291022,"score_gpt":0.33331886224312557,"score_spread":0.28031246095021534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122998269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86109585,0.04405467,0.006229572,0.03618102,0.0026404269,0.013307617,0.000014394273,0.0008257391,0.035650708],"genre_scores_gemma":[0.99725854,0.0010479996,0.000045069395,0.0012502708,0.000082286875,0.00010839082,5.405254e-7,0.000031514497,0.00017536948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978731,0.0005147698,0.0002997586,0.00039274758,0.0004880809,0.00043151152],"domain_scores_gemma":[0.99847424,0.00091502763,0.00013993967,0.00033408278,0.00006067647,0.00007600524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005965744,0.00019469664,0.0001999046,0.000136129,0.00022873832,0.00003222551,0.0004184652,0.00005377951,0.00003648111],"category_scores_gemma":[0.00013014124,0.000117885764,0.000063065745,0.00042885068,0.00028617808,0.000098751974,0.000053684642,0.00042675453,0.000027169215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003977038,0.0008052936,0.0026261883,0.00003340717,0.00003285225,0.00008674038,0.004859523,0.000016322982,0.6485203,0.010586812,0.000081979335,0.32837355],"study_design_scores_gemma":[0.000563136,0.0017819138,0.009459378,0.0001423819,0.0000011292204,0.00011823027,0.0013447516,0.0002491069,0.88255006,0.00085871905,0.102733545,0.00019763761],"about_ca_topic_score_codex":0.000028579827,"about_ca_topic_score_gemma":0.000022902463,"teacher_disagreement_score":0.3281759,"about_ca_system_score_codex":0.000049905775,"about_ca_system_score_gemma":0.000052747087,"threshold_uncertainty_score":0.48072422},"labels":[],"label_agreement":null},{"id":"W2123573411","doi":"10.1517/14728222.2014.920326","title":"Lipoprotein(a) as a therapeutic target in cardiovascular disease","year":2014,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"Canadian Institutes of Health Research","keywords":"Disease; Medicine; Lipoprotein; Atherosclerotic cardiovascular disease; Bioinformatics; Pharmacology; Cholesterol; Intensive care medicine; Internal medicine; Biology","score_opus":0.049954008884343266,"score_gpt":0.35039131917059474,"score_spread":0.3004373102862515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123573411","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[8.3698876e-7,0.98900974,0.00073229836,0.00048132287,0.0018783655,0.0060430667,0.000029661955,0.00026729965,0.0015574086],"genre_scores_gemma":[0.00024686017,0.9897751,0.0002663322,0.002778754,0.0030310387,0.0026126776,0.00051385176,0.00043335275,0.0003419915],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99165714,0.0015430483,0.001448736,0.0019266944,0.0021448762,0.0012794907],"domain_scores_gemma":[0.99443984,0.00016722376,0.00038286683,0.0039540716,0.00013436381,0.00092166296],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0020019242,0.0015007975,0.0059428792,0.0007879329,0.00021325765,0.000084956744,0.0006178117,0.0008974539,0.00051098433],"category_scores_gemma":[0.00013706657,0.0011317082,0.0056117903,0.00078360987,0.00015606609,0.00010608567,0.00012772191,0.0015016458,0.0009478441],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021475817,0.0004711301,0.0000023107477,0.00696904,0.0036768643,0.00018382705,0.00017514601,0.000013734697,6.3120365e-7,0.000882708,0.0002867241,0.98712313],"study_design_scores_gemma":[0.002049154,0.000635116,0.00004137501,0.01261656,0.0005390742,0.00018222068,0.000032529853,0.0000500322,0.000007945518,0.0004702049,0.98227787,0.0010979436],"about_ca_topic_score_codex":0.0003436706,"about_ca_topic_score_gemma":0.0000018293987,"teacher_disagreement_score":0.98602515,"about_ca_system_score_codex":0.00072484894,"about_ca_system_score_gemma":0.0014367603,"threshold_uncertainty_score":0.99983},"labels":[],"label_agreement":null},{"id":"W2131003727","doi":"10.1517/14728222.6.2.203","title":"Identification of new therapeutic targets for prevention of CNS inflammation","year":2002,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Microglia; Immunology; Tumor necrosis factor alpha; Multiple sclerosis; Inflammation; Central nervous system; Receptor; Nitric oxide; Biology; CD8; Interferon gamma; Cell biology; Cytokine; Immune system; Neuroscience; Endocrinology; Biochemistry","score_opus":0.1540337572631458,"score_gpt":0.382855082744361,"score_spread":0.22882132548121517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131003727","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000004901583,0.96476805,0.028422724,0.00022150943,0.0026360287,0.0035254457,0.00009299736,0.00015622965,0.0001721052],"genre_scores_gemma":[0.000510651,0.99569345,0.00029585324,0.0002312048,0.0005274981,0.00041537854,0.00018968509,0.00014274647,0.0019935125],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99509263,0.00069739536,0.0021389185,0.0009320959,0.00076165405,0.0003773325],"domain_scores_gemma":[0.9957394,0.0005458691,0.002543151,0.0008782328,0.00016247865,0.00013089264],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039077405,0.0006372713,0.0013075757,0.0006131654,0.00018815139,0.00006602692,0.0006453882,0.00038033715,0.00036261172],"category_scores_gemma":[0.00026520548,0.00057058915,0.0008015627,0.0005351339,0.00008504843,0.0003094028,0.000047607322,0.000269536,0.00009846778],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054411354,0.00019544743,3.7412473e-8,0.0012563,0.000048594862,4.227107e-7,0.0005033337,0.000031685642,0.0820497,0.01622603,0.0009196523,0.89871436],"study_design_scores_gemma":[0.00052165304,0.0003692439,5.24774e-7,0.0007757988,0.00004359698,0.0000076086862,0.000012172283,0.0005929759,0.32277116,0.0017518301,0.6728208,0.00033264438],"about_ca_topic_score_codex":0.0000012984162,"about_ca_topic_score_gemma":5.700904e-7,"teacher_disagreement_score":0.8983817,"about_ca_system_score_codex":0.0000910157,"about_ca_system_score_gemma":0.00019194973,"threshold_uncertainty_score":0.99967456},"labels":[],"label_agreement":null},{"id":"W2143053439","doi":"10.1517/14728222.12.6.717","title":"The paraventricular nucleus of the hypothalamus – a potential target for integrative treatment of autonomic dysfunction","year":2008,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":319,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Queen's University","funders":"National Heart, Lung, and Blood Institute","keywords":"Hypothalamus; Neuroscience; Nucleus; Afferent; Medicine; Heart failure; Median preoptic nucleus; Subfornical organ; Autonomic nervous system; Glutamate receptor; Biology; Internal medicine; Angiotensin II; Heart rate; Blood pressure; Receptor","score_opus":0.0776118878994255,"score_gpt":0.3412326497276831,"score_spread":0.26362076182825755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143053439","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000021941367,0.9918525,0.0007148667,0.00022994248,0.00426245,0.002600106,0.00015231594,0.000035265137,0.00013061159],"genre_scores_gemma":[0.0008796258,0.9978095,0.00007053385,0.0002179082,0.00019881559,0.00044823127,0.000014318036,0.000049289247,0.00031171902],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971406,0.00062283315,0.0007795732,0.000622768,0.00047744808,0.00035677757],"domain_scores_gemma":[0.99746287,0.00070756284,0.0009829064,0.0007066387,0.000071263785,0.00006875387],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012668609,0.0004882583,0.00093430997,0.00014263297,0.0005696887,0.000045660003,0.00072141684,0.00017638721,0.000026795768],"category_scores_gemma":[0.00017987775,0.00022562187,0.0011781487,0.00036088572,0.00047880446,0.00007511233,0.000046787056,0.00016126347,0.000015124473],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097545526,0.00038860668,2.6934953e-7,0.00006756005,0.000057401456,0.0000020399239,0.00037266838,0.000043380838,0.001304569,0.0013793996,0.00038126565,0.9959053],"study_design_scores_gemma":[0.000587253,0.0012084395,0.0000028379297,0.00028547208,0.00002129132,0.000038190803,0.000040657626,0.00038248784,0.01885849,0.00016480924,0.9782012,0.00020886376],"about_ca_topic_score_codex":0.000007061143,"about_ca_topic_score_gemma":5.5361215e-7,"teacher_disagreement_score":0.9956964,"about_ca_system_score_codex":0.00021253385,"about_ca_system_score_gemma":0.0003353514,"threshold_uncertainty_score":0.9200593},"labels":[],"label_agreement":null},{"id":"W2144427044","doi":"10.1517/14728222.2014.938052","title":"DNMTs as potential therapeutic targets in high-risk pediatric embryonal brain tumors","year":2014,"lang":"en","type":"editorial","venue":"Expert Opinion on Therapeutic Targets","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Epigenetics; DNA methylation; Biology; Phenotype; Epigenomics; Brain tumor; Cancer research; Gene silencing; Methyltransferase; Bioinformatics; Gene; Methylation; Genetics; Pathology; Gene expression; Medicine","score_opus":0.007785674253456142,"score_gpt":0.27958923293392773,"score_spread":0.27180355868047157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144427044","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004844421,0.26536706,0.0051063695,0.00071813277,0.72182447,0.0012059615,0.00031742948,0.000106517604,0.000509615],"genre_scores_gemma":[0.19527306,0.06782421,0.00038007592,0.0013737332,0.7260185,0.00027666523,0.007215637,0.00041344503,0.0012247167],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9943279,0.00093885313,0.00097360613,0.0015931441,0.0012094941,0.0009570065],"domain_scores_gemma":[0.99732745,0.00035750103,0.00072304026,0.0010580248,0.00026524093,0.00026872093],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0010446135,0.0010027059,0.00084203255,0.00042008952,0.00026045056,0.000120683675,0.0008176054,0.0019527237,0.00025819486],"category_scores_gemma":[0.00047142425,0.00096291455,0.00042813682,0.00025199133,0.00012193419,0.00001261596,0.00019294239,0.0011340396,0.00013802733],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018992312,0.0010956305,0.0005956825,0.00013128073,0.00057115307,0.00003351018,0.0006592811,0.0014995368,0.042713054,0.0003200402,0.8907804,0.05970122],"study_design_scores_gemma":[0.0025333988,0.0018487468,0.0011143925,0.000049432278,0.000027779613,0.0000022446084,0.00003908817,0.00015249946,0.011223406,0.0021226755,0.97969186,0.0011944973],"about_ca_topic_score_codex":0.00026693032,"about_ca_topic_score_gemma":0.00004638331,"teacher_disagreement_score":0.19754286,"about_ca_system_score_codex":0.0001312965,"about_ca_system_score_gemma":0.0005427842,"threshold_uncertainty_score":0.999343},"labels":[],"label_agreement":null},{"id":"W2145633869","doi":"10.1517/14728222.10.5.777","title":"Novel targets in prostate cancer","year":2006,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Prostate cancer; Medicine; Context (archaeology); Sorafenib; Prostate; Cancer; Disease; Oncology; Internal medicine; Cancer research; Bioinformatics; Biology","score_opus":0.040874257755146005,"score_gpt":0.35918908279755435,"score_spread":0.3183148250424083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145633869","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.060254276,0.84737635,0.0005150504,0.060720526,0.0048582694,0.0057776975,0.00018652408,0.00061630254,0.01969504],"genre_scores_gemma":[0.9737226,0.015765231,0.0005479048,0.002932011,0.00077625294,0.0006713897,0.00024878458,0.00008437856,0.0052514942],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982433,0.000039907103,0.0002926677,0.00043370944,0.00042498048,0.0005654676],"domain_scores_gemma":[0.9994143,0.00004520356,0.00006157821,0.0002831262,0.0000770744,0.00011871202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013888751,0.000256042,0.00031909262,0.00021962576,0.000091029695,0.000024208819,0.00010425748,0.00009274236,0.0004761202],"category_scores_gemma":[0.0000076292417,0.00018832734,0.00009558646,0.00027462756,0.00008853528,0.00008754478,0.00002767879,0.00025046,0.000070925336],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011857335,0.009842674,0.089843705,0.00027435698,0.0006830443,0.00040822895,0.00857684,0.000299027,0.46931192,0.007835261,0.05403544,0.34703216],"study_design_scores_gemma":[0.012463493,0.0009529851,0.09594835,0.00037286,0.000007224775,0.000029858073,0.00028057586,0.0004921285,0.089963116,0.0009821247,0.7979818,0.00052545744],"about_ca_topic_score_codex":0.00092889415,"about_ca_topic_score_gemma":0.000050846058,"teacher_disagreement_score":0.9134683,"about_ca_system_score_codex":0.00035118253,"about_ca_system_score_gemma":0.00018958858,"threshold_uncertainty_score":0.7679766},"labels":[],"label_agreement":null},{"id":"W2151900613","doi":"10.1517/14728222.10.4.533","title":"Targeting invading macrophage- derived PGE<sub>2</sub>, IL-6 and calcitonin gene-related peptide in injured nerve to treat neuropathic pain","year":2006,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Neuropathic pain; Medicine; Nerve injury; Dorsal root ganglion; Nociceptor; Downregulation and upregulation; Calcitonin gene-related peptide; Nociception; Neuroscience; Inflammation; Calcitonin; Immunology; Pharmacology; Neuropeptide; Anesthesia; Internal medicine; Receptor; Biology; Anatomy; Dorsum","score_opus":0.03642749677400548,"score_gpt":0.32260902211144105,"score_spread":0.28618152533743557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151900613","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0024024618,0.9931165,0.0004855513,0.00020257862,0.00075334153,0.0027003742,0.00006006968,0.00019596696,0.00008313639],"genre_scores_gemma":[0.009248156,0.98604566,0.000916339,0.0014271708,0.00039222243,0.00060464937,0.00092327595,0.00032540658,0.00011711444],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9934428,0.00226547,0.0013570987,0.0014124032,0.00053344923,0.0009888299],"domain_scores_gemma":[0.99774176,0.000610071,0.00046668842,0.0006467927,0.00007284174,0.00046182476],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001640029,0.0012493485,0.002492861,0.00079647265,0.00025079312,0.00008163905,0.0002611021,0.000756159,0.000035524958],"category_scores_gemma":[0.00027174753,0.0010132301,0.0004847979,0.0006872471,0.000076957724,0.00009095753,0.00012707865,0.0009230478,0.00010212251],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014210194,0.0004522915,0.00007364206,0.0013177576,0.0002881214,0.0007463303,0.00079942774,0.000011992478,0.023079956,0.000052896117,0.00052186195,0.9725136],"study_design_scores_gemma":[0.0080995215,0.0037758567,0.00060800405,0.031367406,0.00055539847,0.0005465403,0.0002600967,0.0012621237,0.02048666,0.00030602913,0.92919654,0.0035358134],"about_ca_topic_score_codex":0.00012892981,"about_ca_topic_score_gemma":0.000006234465,"teacher_disagreement_score":0.9689778,"about_ca_system_score_codex":0.00058325013,"about_ca_system_score_gemma":0.00022753925,"threshold_uncertainty_score":0.9992318},"labels":[],"label_agreement":null},{"id":"W2155473026","doi":"10.1517/14728222.2010.487866","title":"Gap junctions and connexins as therapeutic targets in cancer","year":2010,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Connexin; Gap junction; Bystander effect; Cancer; Biology; Cancer cell; Metastasis; Cell biology; Neuroscience; Cancer research; Intracellular; Immunology; Genetics","score_opus":0.06742477997633876,"score_gpt":0.38578397060782543,"score_spread":0.31835919063148665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155473026","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00001879021,0.99406815,0.00007278393,0.00044671752,0.003413772,0.0008677689,0.00007926694,0.000036531208,0.000996238],"genre_scores_gemma":[0.00085197145,0.9932562,0.000050501534,0.0025085316,0.0011111895,0.00062019116,0.0005977979,0.00012398534,0.00087962335],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971667,0.00035592212,0.0006061095,0.0010892594,0.00016752214,0.0006144855],"domain_scores_gemma":[0.9986451,0.00008131496,0.00027879,0.0007518766,0.00006861164,0.00017430022],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025769384,0.0007588196,0.0011338358,0.00025256773,0.00017563529,0.000045956145,0.00039652144,0.0011896519,0.00055179885],"category_scores_gemma":[0.00004019582,0.0006011152,0.00037487975,0.00017744846,0.00023583193,0.00000673739,0.00014055506,0.0007437101,0.00006704276],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081550854,0.00019853922,0.000013011785,0.0002063044,0.00025947054,0.000004817338,0.00017570819,4.7086547e-7,0.0012402755,0.001388816,0.0013022644,0.99512875],"study_design_scores_gemma":[0.0005954928,0.00058418576,0.000028166027,0.0005324255,0.000032343694,0.000058211997,0.0000624548,0.0000057483567,0.00022243107,0.00022296575,0.99694884,0.0007067601],"about_ca_topic_score_codex":0.000115899275,"about_ca_topic_score_gemma":0.00018966262,"teacher_disagreement_score":0.99564654,"about_ca_system_score_codex":0.000064030784,"about_ca_system_score_gemma":0.00037825335,"threshold_uncertainty_score":0.99964404},"labels":[],"label_agreement":null},{"id":"W2156788906","doi":"10.1517/14728222.12.10.1265","title":"Targeting glycogen synthase kinase-3 (GSK-3) in the treatment of Type 2 diabetes","year":2008,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"GSK-3; Glycogen synthase; Regulator; Diabetes mellitus; Enzyme; Type 2 diabetes; Biology; Glycogen; Insulin resistance; GSK3B; Glucose homeostasis; Kinase; Cell biology; Pharmacology; Biochemistry; Chemistry; Endocrinology; Gene","score_opus":0.05179947035749451,"score_gpt":0.33786220533901995,"score_spread":0.28606273498152546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156788906","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015077097,0.9980575,0.000008976993,0.000043611195,0.00088543276,0.00064630783,0.00002341062,0.000012352783,0.0001716429],"genre_scores_gemma":[0.000813243,0.99680954,0.00012229515,0.00024441702,0.00062462065,0.0003248317,0.0008891407,0.00006526501,0.00010663423],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980492,0.00029827727,0.0005395749,0.0005024501,0.00024294874,0.00036757902],"domain_scores_gemma":[0.9990459,0.00010150377,0.00027048224,0.0004810536,0.000054132117,0.000046945417],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015559267,0.00048786568,0.0007861003,0.00010587449,0.00009595068,0.000015581367,0.0004362637,0.00033510532,0.000078707715],"category_scores_gemma":[0.000025972964,0.00030605495,0.00035503364,0.00021401068,0.00009298031,0.0000030309443,0.000031763047,0.00012188856,0.000024926869],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008268256,0.0006293835,0.00003464362,0.00031407425,0.0004947857,0.000008632579,0.00094196456,0.000011541975,0.0013867369,0.000022191702,0.006400434,0.9896729],"study_design_scores_gemma":[0.00033925398,0.00079679117,0.0000039684087,0.000657535,0.000018207538,0.0000049689856,0.000054237236,0.000004079009,0.002853153,0.000008704268,0.99491,0.00034910964],"about_ca_topic_score_codex":0.000008108358,"about_ca_topic_score_gemma":7.183171e-7,"teacher_disagreement_score":0.9893238,"about_ca_system_score_codex":0.00007890326,"about_ca_system_score_gemma":0.00022351953,"threshold_uncertainty_score":0.99993914},"labels":[],"label_agreement":null},{"id":"W2162845412","doi":"10.1517/14728222.11.10.1339","title":"c-Jun N-terminal kinases as potential therapeutic targets","year":2007,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"University of Otago","keywords":"Kinase; Disease; Signal transduction; Inflammation; Pathogenesis; p38 mitogen-activated protein kinases; Diabetes mellitus; c-jun; Cancer; Bioinformatics; Medicine; Immunology; Biology; Cancer research; Neuroscience; Cell biology; Gene; Protein kinase A; Genetics; Transcription factor; Pathology; Endocrinology","score_opus":0.0574021792479626,"score_gpt":0.36577426696190085,"score_spread":0.30837208771393826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162845412","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000006074574,0.99073976,0.0011578118,0.00006328338,0.004374149,0.0010670911,0.000086584194,0.00009302363,0.0024122477],"genre_scores_gemma":[0.000548132,0.9892957,0.00019530734,0.0021269314,0.0035682956,0.00025075665,0.0022430941,0.00025021608,0.0015215403],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99559474,0.0004339833,0.0009285364,0.0014074807,0.00059914147,0.001036136],"domain_scores_gemma":[0.997691,0.00007521564,0.00051771314,0.0012619055,0.000115208044,0.00033896993],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039867565,0.0012283843,0.0014676712,0.00030741774,0.0003029041,0.000095912284,0.000924034,0.0012195931,0.0006136578],"category_scores_gemma":[0.000035699322,0.001000169,0.0011414398,0.00020458309,0.00019024368,0.000010730682,0.00021123064,0.0005616918,0.000582794],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018032285,0.0003427924,7.061707e-7,0.0005748568,0.0005191989,0.00011106668,0.00009493269,0.0000010837599,0.0014902246,0.00047874142,0.0048900135,0.9913161],"study_design_scores_gemma":[0.0005954304,0.0013953669,0.000003745911,0.0008912888,0.00008013123,0.00048139726,0.00005074612,0.0000038872513,0.0027409268,0.0001369341,0.99248224,0.001137902],"about_ca_topic_score_codex":0.000016767659,"about_ca_topic_score_gemma":0.0000025435675,"teacher_disagreement_score":0.99017817,"about_ca_system_score_codex":0.000091983406,"about_ca_system_score_gemma":0.00045605205,"threshold_uncertainty_score":0.99924487},"labels":[],"label_agreement":null},{"id":"W2166861359","doi":"10.1517/14728222.10.2.289","title":"The emerging importance of DNA mapping and other comprehensive screening techniques, as tools to identify new drug targets and as a means of (cancer) therapy personalisation","year":2006,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"","keywords":"Computational biology; Personalized medicine; Drug; Drug discovery; Biology; Human genome; Precision medicine; Single-nucleotide polymorphism; Bioinformatics; Gene; Genome; Pharmacology; Genetics","score_opus":0.08813478646019927,"score_gpt":0.40229858041891026,"score_spread":0.31416379395871097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166861359","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00033709695,0.9965219,0.0013383375,0.00041389928,0.00022768218,0.0009658448,0.00003289521,0.000017965893,0.00014440983],"genre_scores_gemma":[0.0009693272,0.99639714,0.0007394126,0.00088679214,0.000319567,0.00023320092,0.00011386808,0.000064809064,0.00027588042],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99808884,0.00021102215,0.00060405687,0.0005733583,0.00029008082,0.00023262048],"domain_scores_gemma":[0.99861515,0.00007237782,0.00066339877,0.00043936586,0.00011722468,0.0000925147],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023830261,0.00038108166,0.0006050642,0.00012769656,0.00016012524,0.00004931952,0.00027499447,0.00021828465,0.00002831561],"category_scores_gemma":[0.000024803923,0.00027977963,0.0001934618,0.00016913912,0.00010529532,0.000010913709,0.0000787702,0.00014154214,9.776332e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010803584,0.000027898583,0.000031515934,0.00022511715,0.00019041807,2.0441693e-7,0.0008006713,0.0000018447718,0.036418248,0.00020311377,0.0031723073,0.95882064],"study_design_scores_gemma":[0.00028755335,0.00014422322,0.0001577322,0.0015335499,0.000013892561,0.0000050617255,0.00049627613,0.00000541229,0.019087175,0.000087150474,0.9778958,0.00028618748],"about_ca_topic_score_codex":0.00016914717,"about_ca_topic_score_gemma":0.000013042673,"teacher_disagreement_score":0.97472346,"about_ca_system_score_codex":0.000028995184,"about_ca_system_score_gemma":0.00016250252,"threshold_uncertainty_score":0.9999654},"labels":[],"label_agreement":null},{"id":"W2166922847","doi":"10.1517/14728222.12.10.1289","title":"Proprotein convertases as therapeutic targets","year":2008,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; Ottawa Hospital; University of Ottawa","funders":"","keywords":"Proprotein Convertases; Proteases; Furin; Proprotein convertase; Serine; Biology; Cancer research; Bioinformatics; Enzyme; Medicine; Pharmacology; Biochemistry; Lipoprotein; Cholesterol; LDL receptor","score_opus":0.026145055120697806,"score_gpt":0.28257703260044015,"score_spread":0.25643197747974233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166922847","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.094505385,0.83150625,0.023280276,0.009661079,0.010741976,0.009222366,0.00019070637,0.0010771765,0.0198148],"genre_scores_gemma":[0.97988385,0.00535836,0.00044697235,0.011278319,0.0009221083,0.00033741177,0.0002612267,0.00009339484,0.0014183568],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978719,0.00016897789,0.0003239209,0.00069790106,0.00039072783,0.00054658955],"domain_scores_gemma":[0.99888414,0.000017120787,0.00013026994,0.0006762962,0.000099940335,0.00019225453],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014335896,0.00042614617,0.000296962,0.00007861764,0.00034608447,0.000025801977,0.00035952084,0.00029348064,0.0006041119],"category_scores_gemma":[0.00003460947,0.0003588211,0.00020163358,0.00010276891,0.00015154327,0.0000144678,0.000082138555,0.00019416653,0.0003613265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005997838,0.0004673619,0.00004522305,0.000010912786,0.00021117258,0.000024109948,0.00052676356,0.000006447732,0.9727425,0.0022059672,0.011087831,0.012071933],"study_design_scores_gemma":[0.0006958123,0.0011106534,0.000045270368,0.000010645841,0.0000036105862,0.000055684468,0.00006429805,0.000025762232,0.6238646,0.00074812333,0.3730358,0.00033976542],"about_ca_topic_score_codex":0.000041299423,"about_ca_topic_score_gemma":0.0000015670006,"teacher_disagreement_score":0.8853785,"about_ca_system_score_codex":0.00003480797,"about_ca_system_score_gemma":0.00016658657,"threshold_uncertainty_score":0.9998864},"labels":[],"label_agreement":null},{"id":"W2168448982","doi":"10.1517/14728222.6.2.185","title":"Novel G-protein-coupled receptor genes expressed in the brain: continued discovery of important therapeutic targets","year":2002,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Receptor; Drug discovery; Biology; Rhodopsin-like receptors; Signal transduction; Neuroscience; Computational biology; Class C GPCR; Neurotransmitter receptor; Metabotropic receptor; Bioinformatics; Cell biology; Genetics; Glutamate receptor","score_opus":0.04743990798451598,"score_gpt":0.3136720887402553,"score_spread":0.26623218075573934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168448982","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005535588,0.99389553,0.0025743912,0.0001921887,0.001143481,0.0018915622,0.00015243913,0.000023638533,0.00007142137],"genre_scores_gemma":[0.0013522479,0.9943788,0.00043535515,0.00091474544,0.0008640811,0.00068319583,0.0008551135,0.00017374664,0.00034270337],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.995723,0.00055297493,0.0013959741,0.0010641861,0.000578683,0.0006851642],"domain_scores_gemma":[0.9974675,0.00018366028,0.00096535275,0.0011977692,0.00009472123,0.0000909867],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008239716,0.0009446381,0.0016215974,0.00019903733,0.0001439689,0.00009857694,0.0011230846,0.0007611799,0.00032213744],"category_scores_gemma":[0.00006856887,0.0006255846,0.0009221148,0.00028426474,0.00013672146,0.00001892351,0.00011796873,0.0004620203,0.000015941767],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001849447,0.00073064334,0.0000015153435,0.00077460404,0.0006026595,0.0000049173204,0.0007249811,0.0000059023882,0.59699595,0.00070322555,0.0015073512,0.3977633],"study_design_scores_gemma":[0.00089984154,0.00058060116,0.0000013058232,0.0015602327,0.000030065174,0.000013467675,0.00020143816,0.000041526662,0.0339172,0.00007442408,0.96194184,0.00073807425],"about_ca_topic_score_codex":0.000030713687,"about_ca_topic_score_gemma":0.0000047320664,"teacher_disagreement_score":0.9604345,"about_ca_system_score_codex":0.000057493162,"about_ca_system_score_gemma":0.00018587845,"threshold_uncertainty_score":0.99961954},"labels":[],"label_agreement":null},{"id":"W2169040543","doi":"10.1517/14728222.2014.887683","title":"Targeting cell surface trafficking of pain-facilitating receptors to treat chronic pain conditions","year":2014,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Nociceptor; Chronic pain; Receptor; Neuroscience; Sensitization; Transient receptor potential channel; Medicine; Nociception; Dorsal root ganglion; Nerve injury; Spinal cord; Biology; Internal medicine","score_opus":0.04591767924314502,"score_gpt":0.3591585857157716,"score_spread":0.3132409064726266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169040543","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000140970305,0.9884963,0.00781819,0.00015153852,0.00092535425,0.002073154,0.00007110791,0.0001700163,0.00028023936],"genre_scores_gemma":[0.0010152971,0.99142486,0.0041053826,0.00081739074,0.0004942875,0.00028223955,0.0012402048,0.0001920093,0.00042832555],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99478203,0.0019061986,0.0011641494,0.0008899256,0.0005482266,0.000709477],"domain_scores_gemma":[0.99619865,0.0020639172,0.0006065964,0.00067688007,0.00011985026,0.0003340826],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0022954422,0.0008757296,0.0024352316,0.0003053382,0.00025002047,0.000026508525,0.0002669671,0.0004497368,0.0005577351],"category_scores_gemma":[0.0003226316,0.00068765227,0.00079076184,0.00039471404,0.000063731546,0.000048487233,0.000045359175,0.00044728295,0.00017561753],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003747638,0.00047734758,0.000005100196,0.00848051,0.00035970437,0.000008883977,0.0014932456,0.000120485995,0.00047422748,0.00008346057,0.0032875966,0.985172],"study_design_scores_gemma":[0.00096502755,0.0021769612,6.811358e-7,0.013520476,0.00012619143,0.000005985782,0.00044302174,0.0004433663,0.00041424725,0.000021225243,0.98131454,0.0005682931],"about_ca_topic_score_codex":0.00002909977,"about_ca_topic_score_gemma":8.656727e-7,"teacher_disagreement_score":0.98460364,"about_ca_system_score_codex":0.00066862,"about_ca_system_score_gemma":0.00033584106,"threshold_uncertainty_score":0.99955744},"labels":[],"label_agreement":null},{"id":"W2169050233","doi":"10.1517/14728222.11.12.1523","title":"Targeting platelets for prevention and treatment of cardiovascular disease","year":2007,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Pomegranate: compositions and health benefits","field":"Nursing","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Florida State University","keywords":"Platelet; Medicine; Disease; Thrombosis; Nutraceutical; Platelet activation; Stroke (engine); Platelet aggregation; Bioinformatics; Internal medicine; Pathology; Biology","score_opus":0.1308887943018832,"score_gpt":0.41184152655984146,"score_spread":0.28095273225795825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169050233","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000044009607,0.9938785,0.0011362862,0.000094272196,0.0019449778,0.0026919665,0.00014773721,0.0000677505,0.00003412742],"genre_scores_gemma":[0.00011970734,0.99698913,0.00080417475,0.00009389972,0.0006731589,0.00051443523,0.00066919025,0.000105678184,0.00003062129],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975632,0.00021646873,0.00079358084,0.00063331734,0.00031261143,0.0004808273],"domain_scores_gemma":[0.9985364,0.0002982084,0.00035266092,0.0005050697,0.0000792547,0.00022842252],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030650847,0.00053741777,0.0016214936,0.00033859906,0.0003119063,0.000027966937,0.0001372884,0.00028073374,0.000020485482],"category_scores_gemma":[0.0000142331655,0.0004269556,0.0011120342,0.00016030588,0.000053928095,0.00006540213,0.000016786084,0.00012402901,0.000006908721],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027016172,0.0003722837,5.417439e-7,0.0025809703,0.0008185693,0.0000025404768,0.0002829148,0.000021820611,0.0000018948647,0.00021899487,0.00013541356,0.9952939],"study_design_scores_gemma":[0.001013365,0.0011610857,0.0000066011758,0.004040449,0.0003105274,0.000006106043,0.000021326468,0.000116612275,0.000026364625,0.00016610722,0.9927546,0.00037688026],"about_ca_topic_score_codex":0.00003660444,"about_ca_topic_score_gemma":6.179198e-7,"teacher_disagreement_score":0.99491704,"about_ca_system_score_codex":0.00030820165,"about_ca_system_score_gemma":0.00008276828,"threshold_uncertainty_score":0.9998182},"labels":[],"label_agreement":null},{"id":"W2170877463","doi":"10.1517/14728222.2014.936382","title":"Consideration of GREB1 as a potential therapeutic target for hormone-responsive or endocrine-resistant cancers","year":2014,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Prostate cancer; Estrogen; Breast cancer; Hormone; Cancer research; Cancer; Medicine; Bioinformatics; Biology; Internal medicine","score_opus":0.0314190946749713,"score_gpt":0.35908308866243205,"score_spread":0.32766399398746077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170877463","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00002039169,0.9939544,0.0018453567,0.000121743826,0.0014381976,0.002290941,0.00016491047,0.000039032457,0.00012503569],"genre_scores_gemma":[0.0027279835,0.9927075,0.00048108285,0.0006288383,0.00086282566,0.0007164742,0.0012281723,0.0001812042,0.00046595564],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99666494,0.00058419467,0.00090110727,0.00090091303,0.00035189185,0.0005969638],"domain_scores_gemma":[0.99788266,0.00025672486,0.0007341682,0.0007369056,0.00021417599,0.00017537319],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031405274,0.0008232085,0.001515413,0.00021287915,0.00021514263,0.00004598325,0.00041260623,0.0007790956,0.000060930703],"category_scores_gemma":[0.0001350373,0.0005877118,0.0009553817,0.00015672344,0.00018916938,0.000008153956,0.00007526234,0.00032567163,0.000026906127],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007080589,0.00033237186,2.5909705e-7,0.0020645799,0.0033844956,0.000023906643,0.0002279273,0.00009112654,0.03928619,0.0012493818,0.009010739,0.9372484],"study_design_scores_gemma":[0.0015959654,0.004799977,6.3567603e-7,0.0008760603,0.00015747992,0.00009195047,0.000063432904,0.00006283072,0.011867814,0.00017574466,0.97961086,0.0006972545],"about_ca_topic_score_codex":0.0000311718,"about_ca_topic_score_gemma":0.0000026251687,"teacher_disagreement_score":0.9706001,"about_ca_system_score_codex":0.0001264194,"about_ca_system_score_gemma":0.0010872694,"threshold_uncertainty_score":0.99965745},"labels":[],"label_agreement":null},{"id":"W2170918501","doi":"10.1517/14728222.8.5.473","title":"Regulation of MMP-9 gene expression for the development of novel molecular targets against cancer and inflammatory diseases","year":2004,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Matrix metalloproteinase; Gene expression; Inflammation; Biology; Cancer; Bioinformatics; Computational biology; Signal transduction; Regulation of gene expression; Cancer research; Gene; Cell biology; Immunology; Genetics","score_opus":0.036853470002914036,"score_gpt":0.3278280470816489,"score_spread":0.29097457707873486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170918501","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000067269546,0.9823628,0.015727764,0.000019147223,0.000422293,0.0012773387,0.00010661572,0.000008692037,0.000008075446],"genre_scores_gemma":[0.0025327662,0.9922052,0.0034375938,0.00010371515,0.0002507715,0.00080428604,0.00058486836,0.00006414781,0.000016655582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985323,0.00005538432,0.0005695554,0.00041722477,0.00022221186,0.00020335708],"domain_scores_gemma":[0.99889195,0.000035030313,0.0004999098,0.0004059605,0.000099239056,0.00006790115],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014621035,0.00035220556,0.0005477843,0.00006903939,0.000112266775,0.000008923897,0.00022802404,0.0002862232,0.000006787761],"category_scores_gemma":[0.000024381608,0.00023912157,0.00026039509,0.000052696425,0.00007249407,0.0000056769386,0.000094699804,0.000079226054,3.9894925e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010008911,0.00015847925,6.166916e-7,0.0019176789,0.00029564838,1.6338986e-7,0.00016243388,0.0000475831,0.58300334,0.0002023301,0.00008174337,0.4140299],"study_design_scores_gemma":[0.00046211513,0.00009714257,0.0000048039324,0.002515277,0.000027249325,7.732853e-7,0.000012577944,0.000012165741,0.52503884,0.00003947403,0.47158003,0.00020957377],"about_ca_topic_score_codex":0.0000019995502,"about_ca_topic_score_gemma":5.083108e-7,"teacher_disagreement_score":0.47149828,"about_ca_system_score_codex":0.000045192926,"about_ca_system_score_gemma":0.00043779195,"threshold_uncertainty_score":0.97510946},"labels":[],"label_agreement":null},{"id":"W2293112675","doi":"10.1517/14728222.2016.1146695","title":"On the horizon: trophic peptide growth factors as therapy for neonatal short bowel syndrome","year":2016,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Clinical Nutrition and Gastroenterology","field":"Nursing","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Short bowel syndrome; Glucagon-like peptide-2; Medicine; Population; Epidermal growth factor; Peptide; Bioinformatics; Internal medicine; Biology; Parenteral nutrition; Receptor; Biochemistry","score_opus":0.07984371693068733,"score_gpt":0.37621662614007323,"score_spread":0.2963729092093859,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2293112675","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009828666,0.9647327,0.00014304231,0.023914717,0.0076737097,0.0029010423,0.00027805832,0.00020578397,0.000052639694],"genre_scores_gemma":[0.0018854769,0.9759604,0.00003179896,0.01925171,0.001159578,0.0009552043,0.00042660855,0.000247759,0.000081518825],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99542946,0.0008578378,0.0011046091,0.0011410904,0.0005577176,0.0009092663],"domain_scores_gemma":[0.99479806,0.0035252282,0.00040127835,0.0009223892,0.00010227902,0.00025078477],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043650993,0.0010676105,0.0018930346,0.00028682203,0.00040680275,0.00009023813,0.0009786934,0.0007284418,0.00054523745],"category_scores_gemma":[0.00022046595,0.0005682336,0.0017744374,0.00016239965,0.00029164532,0.00009031175,0.00005867689,0.0008456048,0.00025586097],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016787758,0.00060450606,0.000004742079,0.00035814708,0.0005794212,0.00001239806,0.00020498478,8.524768e-8,0.0000072249586,0.0015575981,0.03862192,0.9563702],"study_design_scores_gemma":[0.0013785053,0.0082536265,0.00002892397,0.003570389,0.00003019843,0.00008335382,0.00003750087,0.0000018077303,0.000031703832,0.0028089269,0.98323995,0.0005351236],"about_ca_topic_score_codex":0.0000073813353,"about_ca_topic_score_gemma":9.829797e-7,"teacher_disagreement_score":0.95583504,"about_ca_system_score_codex":0.00024708261,"about_ca_system_score_gemma":0.000039554172,"threshold_uncertainty_score":0.9996769},"labels":[],"label_agreement":null},{"id":"W2308800788","doi":"10.1517/14728222.2016.1164695","title":"Calreticulin, a therapeutic target?","year":2016,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Calreticulin; Immunogenic cell death; Unfolded protein response; Endoplasmic reticulum; Cell biology; Biology; Programmed cell death; Extracellular; Cell; Intracellular; Apoptosis; Biochemistry","score_opus":0.03550761811961399,"score_gpt":0.3494242121773451,"score_spread":0.3139165940577311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2308800788","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[5.4208516e-7,0.99339974,0.0011693088,0.00019625839,0.0020735564,0.0009075491,0.00019377588,0.00007668272,0.0019825646],"genre_scores_gemma":[0.0001357753,0.9937443,0.00015510854,0.0015220598,0.0018023689,0.00055015896,0.0008466751,0.00022041347,0.0010231218],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99634457,0.00043188743,0.00074612454,0.0012564554,0.00043921112,0.0007817329],"domain_scores_gemma":[0.99772173,0.00010466241,0.00040572937,0.0013096296,0.00009402059,0.00036419695],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018384165,0.0010295243,0.0012967074,0.0001579677,0.00019206206,0.00007131404,0.00074080954,0.00077886943,0.00064039545],"category_scores_gemma":[0.000059121357,0.00067199336,0.0011039722,0.00014194676,0.0002092674,0.0000066367143,0.00016722133,0.00031607572,0.000558002],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009480677,0.00024159695,0.0000018142886,0.00058939576,0.0005603131,0.000011808397,0.000043454696,0.0000013164165,0.00016354029,0.0010224761,0.009137394,0.98813206],"study_design_scores_gemma":[0.0006425756,0.0004160685,0.0000016128611,0.0023852524,0.00004355342,0.000034707293,0.00001811196,0.000004616382,0.00042266038,0.00022448339,0.9948777,0.00092867116],"about_ca_topic_score_codex":0.0000040555738,"about_ca_topic_score_gemma":4.794842e-7,"teacher_disagreement_score":0.9872034,"about_ca_system_score_codex":0.00008380258,"about_ca_system_score_gemma":0.00038312917,"threshold_uncertainty_score":0.9995731},"labels":[],"label_agreement":null},{"id":"W2769549375","doi":"10.1080/14728222.2018.1406924","title":"Emerging therapeutic targets in myeloproliferative neoplasms and peripheral T-cell leukemia and lymphomas","year":2017,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Hungarian Scientific Research Fund; Canadian Institutes of Health Research; Austrian Science Fund; Österreichische Forschungsförderungsgesellschaft; Canada Research Chairs","keywords":"Biology; Cancer research; Epigenetics; Leukemia; Haematopoiesis; Chromatin remodeling; Myeloproliferative Disorders; JAK-STAT signaling pathway; Cancer; Lymphoma; Carcinogenesis; Signal transduction; Genetics; Immunology; Gene; Stem cell; Receptor tyrosine kinase","score_opus":0.07735420331731752,"score_gpt":0.39340608895262985,"score_spread":0.31605188563531234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769549375","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000031511237,0.99288464,0.00007284459,0.0006569015,0.00088470284,0.0027666646,0.000033547843,0.00012477669,0.0025444373],"genre_scores_gemma":[0.0008666004,0.99368143,0.000513381,0.0013358284,0.0008111337,0.00065611774,0.00026808298,0.00031288777,0.0015545102],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9943866,0.00066545577,0.0011389537,0.0016977562,0.0008260136,0.0012852321],"domain_scores_gemma":[0.9969537,0.00046949863,0.00058814505,0.0012944986,0.00013667348,0.0005574322],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00078660814,0.001442369,0.0033635027,0.0007599933,0.00055822014,0.00025341276,0.00058690994,0.0010217311,0.00041047],"category_scores_gemma":[0.00010398152,0.0011143698,0.0004412601,0.00028652226,0.0005334344,0.0002788443,0.00032610487,0.001684764,0.000072291215],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003700886,0.00018745686,0.00007490973,0.0024102926,0.0004939758,0.0001621545,0.0035193625,0.0000011872122,0.000040840234,0.00035955574,0.0008266557,0.99155354],"study_design_scores_gemma":[0.0040337653,0.0007568499,0.0001788275,0.00521693,0.000075985576,0.00042316297,0.00039406863,0.00067955814,0.00006295305,0.00015848961,0.98698324,0.0010361894],"about_ca_topic_score_codex":0.00012276357,"about_ca_topic_score_gemma":0.000014254,"teacher_disagreement_score":0.9905173,"about_ca_system_score_codex":0.0020508126,"about_ca_system_score_gemma":0.0020503001,"threshold_uncertainty_score":0.99983263},"labels":[],"label_agreement":null},{"id":"W2897137871","doi":"10.1080/14728222.2018.1535595","title":"EGFL7 – a potential therapeutic target for multiple sclerosis?","year":2018,"lang":"en","type":"editorial","venue":"Expert Opinion on Therapeutic Targets","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Multiple sclerosis; Medicine; Neuroscience; Pharmacology; Intensive care medicine; Immunology; Biology","score_opus":0.05885040147917182,"score_gpt":0.335107386461153,"score_spread":0.2762569849819812,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897137871","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000019657673,0.037766322,0.012043023,0.0016468958,0.94426507,0.0022932466,0.00092758675,0.00043738063,0.0006008227],"genre_scores_gemma":[0.015571268,0.0049950876,0.002649259,0.0027947417,0.9655012,0.0010706316,0.005089996,0.00047046898,0.0018573492],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99550784,0.00015768145,0.00088960316,0.0012990452,0.0012107408,0.00093508593],"domain_scores_gemma":[0.9962345,0.00095719064,0.00049857004,0.0010975668,0.0008726779,0.00033954167],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003989571,0.0009606368,0.0012039478,0.0004228746,0.0005322967,0.00015086986,0.0004620648,0.001309562,0.0013562937],"category_scores_gemma":[0.00043537605,0.00080847315,0.0010253107,0.00020849533,0.00020937191,0.00013906693,0.00007790963,0.0011124488,0.00033258897],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030281448,0.00089286116,0.0000037787456,0.000099050434,0.00081678195,0.0000053094714,0.00054454093,0.000010009795,0.028461903,0.00007542924,0.9511613,0.014900892],"study_design_scores_gemma":[0.005092003,0.004535205,0.000026306032,0.00074192486,0.000084378764,0.0000125880015,0.00011601901,0.001151504,0.02011423,0.0003385866,0.96699274,0.0007945367],"about_ca_topic_score_codex":0.00006239042,"about_ca_topic_score_gemma":0.000004477334,"teacher_disagreement_score":0.032771233,"about_ca_system_score_codex":0.0003732911,"about_ca_system_score_gemma":0.00050963095,"threshold_uncertainty_score":0.99998695},"labels":[],"label_agreement":null},{"id":"W2911536945","doi":"10.1080/14728222.2019.1581764","title":"Agmatine as a potential therapeutic intervention in bipolar depression: the preclinical landscape","year":2019,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Agmatine; Polyamine; Neuroprotection; Antidepressant; Bipolar disorder; Depression (economics); Neuroscience; Medicine; Pathophysiology; Inflammation; Pharmacology; Bioinformatics; Biology; Internal medicine; Hippocampus; Biochemistry","score_opus":0.07289562796849804,"score_gpt":0.40789693711439856,"score_spread":0.33500130914590054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911536945","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[5.0939565e-7,0.99381393,0.0001178167,0.00073901325,0.0019012426,0.0027037102,0.000020859958,0.00009955123,0.00060337107],"genre_scores_gemma":[0.0012508511,0.9955243,0.00004333806,0.0007843571,0.00056848436,0.00058172236,0.00057413854,0.00013992761,0.00053289253],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996152,0.0008053143,0.0010698772,0.0008458132,0.00060663733,0.0005203804],"domain_scores_gemma":[0.99788344,0.00035188408,0.00044059812,0.0011222628,0.000055062705,0.00014672958],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005308616,0.00075228786,0.0017831005,0.00030611362,0.00013384385,0.000063006744,0.00043021387,0.00064582226,0.0012162705],"category_scores_gemma":[0.00004085269,0.00041779416,0.0012561284,0.00032466758,0.00008542225,0.00007565868,0.00012186545,0.0010582834,0.00078994816],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000281972,0.0012810306,0.00025650722,0.001266637,0.00078942144,0.000010808931,0.00030290955,0.0000010296922,0.0000017478511,0.00013060051,0.00027664803,0.99540067],"study_design_scores_gemma":[0.0027596548,0.00095082575,0.0008274345,0.0051719807,0.00032448707,0.00020124897,0.000091501824,0.000082520324,0.000005634529,0.000134536,0.98905057,0.00039960744],"about_ca_topic_score_codex":0.000067563466,"about_ca_topic_score_gemma":0.000015602476,"teacher_disagreement_score":0.9950011,"about_ca_system_score_codex":0.00015275108,"about_ca_system_score_gemma":0.00024209655,"threshold_uncertainty_score":0.9999881},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"high"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"split"},{"id":"W2938535502","doi":"10.1080/14728222.2019.1606904","title":"The potential of dopamine receptor D2 (DRD2) as a therapeutic target for tackling pancreatic cancer","year":2019,"lang":"en","type":"editorial","venue":"Expert Opinion on Therapeutic Targets","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Dopamine receptor D2; Pancreatic ductal adenocarcinoma; Pancreatic cancer; Cancer; Dopamine; Adenocarcinoma; Medicine; Cancer research; Receptor; Dopamine receptor; Internal medicine; Oncology; Neuroscience; Biology","score_opus":0.02769456255212246,"score_gpt":0.37656284114343563,"score_spread":0.3488682785913132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2938535502","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041701517,0.27539876,0.0027258126,0.004968321,0.70894736,0.0057711983,0.00046190148,0.00015406388,0.0011555728],"genre_scores_gemma":[0.007711188,0.20076507,0.0019779946,0.001723996,0.7462193,0.0038408202,0.002481519,0.00060893357,0.034671206],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9943721,0.00044857856,0.0011769766,0.0010041515,0.0018394691,0.0011587053],"domain_scores_gemma":[0.99197865,0.00470819,0.00078192604,0.0012530523,0.000993594,0.00028457076],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013019342,0.0008348197,0.002105254,0.0002789949,0.0004807192,0.000070808346,0.0007565347,0.0013486259,0.001064417],"category_scores_gemma":[0.0009098364,0.0005447534,0.00069810357,0.0002629947,0.00046672876,0.00007936294,0.000113527036,0.0012917197,0.00017305212],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011788278,0.00075490057,0.0002307181,0.00068072026,0.0038561395,0.0000070833553,0.0008884049,0.000024884012,0.007237485,0.00041250023,0.91349864,0.06062023],"study_design_scores_gemma":[0.00535984,0.004681762,0.0000818463,0.00085976697,0.00023725012,0.000007735339,0.00040652067,0.0012338243,0.0015726516,0.00050902314,0.98451906,0.0005307334],"about_ca_topic_score_codex":0.00030180797,"about_ca_topic_score_gemma":0.0000067272117,"teacher_disagreement_score":0.07463368,"about_ca_system_score_codex":0.0005595331,"about_ca_system_score_gemma":0.0027496065,"threshold_uncertainty_score":0.99994785},"labels":[],"label_agreement":null},{"id":"W2951436114","doi":"10.1080/14728222.2019.1628948","title":"Cystic Fibrosis: Proteostatic correctors of CFTR trafficking and alternative therapeutic targets.","year":2019,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Proteostasis; Cystic fibrosis; Endoplasmic reticulum; Cystic fibrosis transmembrane conductance regulator; Cell biology; Synthetic lethality; Biology; Endoplasmic-reticulum-associated protein degradation; Mutation; Mutant; Unfolded protein response; Bioinformatics; Cancer research; Genetics; Gene","score_opus":0.07349842931428337,"score_gpt":0.39663231449997216,"score_spread":0.3231338851856888,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951436114","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000008360712,0.9912111,0.0010816633,0.00012405627,0.0017816394,0.0053474074,0.0001426532,0.00013430297,0.00016879123],"genre_scores_gemma":[0.0011397345,0.9944664,0.0019953793,0.0002955056,0.00043125427,0.0007346115,0.00040335194,0.0002737446,0.00025997544],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99436337,0.0007137275,0.0013893413,0.0012772924,0.0013008106,0.00095545506],"domain_scores_gemma":[0.99552506,0.001874746,0.00095370546,0.0010304535,0.00024320211,0.00037281227],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053987006,0.0011701545,0.003619765,0.00073476305,0.00015717393,0.00007350942,0.0005221495,0.00044496468,0.00038389186],"category_scores_gemma":[0.0003268808,0.00085320737,0.0007245469,0.00055363314,0.0004291586,0.00017380062,0.00014555255,0.0010252725,0.00012801208],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005754716,0.00040144293,0.000007847041,0.01382474,0.0011336904,0.000016208674,0.00174759,0.00000987459,0.00023426514,0.00026764008,0.0003703361,0.9814109],"study_design_scores_gemma":[0.0016498547,0.0029883555,0.000050782157,0.028216938,0.0002646251,0.00012181844,0.0002663735,0.00051086064,0.00032901485,0.00015163104,0.96463865,0.000811108],"about_ca_topic_score_codex":0.000038522245,"about_ca_topic_score_gemma":0.0000015811594,"teacher_disagreement_score":0.98059976,"about_ca_system_score_codex":0.00041449605,"about_ca_system_score_gemma":0.0008206098,"threshold_uncertainty_score":0.99939185},"labels":[],"label_agreement":null},{"id":"W3035846272","doi":"10.1080/14728222.2020.1783242","title":"Thymic stromal lymphopoietin: its role and potential as a therapeutic target in asthma","year":2020,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":229,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Thymic stromal lymphopoietin; Asthma; Medicine; Immunology; Pharmacology","score_opus":0.02858444432175242,"score_gpt":0.3366293091842782,"score_spread":0.30804486486252575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035846272","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000018785504,0.99452645,0.000024225272,0.0014943115,0.0010233439,0.0015098852,0.00005406503,0.00016299196,0.0011859279],"genre_scores_gemma":[0.005185116,0.9888688,0.00009255959,0.004180796,0.000605861,0.0003183767,0.00040491327,0.00016273493,0.00018084845],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962268,0.0005850534,0.0008775646,0.0010823248,0.00051831565,0.00070992945],"domain_scores_gemma":[0.99845326,0.0002007431,0.0003213043,0.0005483146,0.000054374384,0.000422018],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018007035,0.00094147125,0.0024581822,0.000395873,0.00014766352,0.00005871082,0.00035785107,0.0007555773,0.0009163049],"category_scores_gemma":[0.00005966346,0.00074835634,0.00062688376,0.00033624042,0.0001675928,0.00011043763,0.00012441729,0.0007656365,0.000556404],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007750398,0.0007282364,0.0000674876,0.002268047,0.0008634683,0.00066430285,0.00076423807,0.0000010276976,0.00003370399,0.00054456224,0.0017843328,0.99150556],"study_design_scores_gemma":[0.0020148524,0.00053440046,0.00026149867,0.0035726076,0.00010908298,0.0012366258,0.00017296721,0.00011688008,0.00003116484,0.00039378038,0.99091476,0.00064138835],"about_ca_topic_score_codex":0.000008716629,"about_ca_topic_score_gemma":4.678419e-7,"teacher_disagreement_score":0.99086416,"about_ca_system_score_codex":0.00016708991,"about_ca_system_score_gemma":0.00068545935,"threshold_uncertainty_score":0.999997},"labels":[],"label_agreement":null},{"id":"W3113060561","doi":"10.1080/14728222.2021.1861249","title":"HSP47: a potential target for fibrotic diseases and implications for therapy","year":2020,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Agence Nationale de la Recherche","keywords":"Fibrosis; In vivo; Medicine; Biomarker; Pathology; Pulmonary fibrosis; Cancer research; Biology; Biochemistry","score_opus":0.07200161049709645,"score_gpt":0.40326501107846185,"score_spread":0.3312634005813654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3113060561","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[8.402655e-7,0.97543395,0.01673471,0.0012996634,0.00032804604,0.0050457604,0.0011010265,0.000037291735,0.000018724999],"genre_scores_gemma":[0.00008630974,0.9866789,0.0017876338,0.00057835196,0.0014867052,0.006322252,0.0027829036,0.00015940967,0.000117512864],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978385,0.00017703889,0.00042047433,0.0009191986,0.00015418425,0.000490632],"domain_scores_gemma":[0.998759,0.00013058865,0.00014713027,0.0005853092,0.000117785836,0.00026022835],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012971056,0.0005042086,0.00083625404,0.00009929168,0.00026548537,0.00007613558,0.00042551552,0.0004005451,0.000027366923],"category_scores_gemma":[0.000113259644,0.00040770913,0.0005916521,0.00010319726,0.000094637864,0.0000054597626,0.00010352084,0.00015270872,0.000008335977],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026138677,0.00013410518,8.6057037e-7,0.0010104725,0.0003854277,3.6107375e-7,0.000027333077,0.0000013286162,0.0015053746,0.00031026534,0.006139893,0.99022317],"study_design_scores_gemma":[0.0008737421,0.0015615843,0.000005217449,0.00030409356,0.000021227817,0.000010559654,0.000007723404,0.00003570148,0.00050604297,0.0004504165,0.9957852,0.00043850805],"about_ca_topic_score_codex":0.0000020610944,"about_ca_topic_score_gemma":1.9094101e-7,"teacher_disagreement_score":0.98978466,"about_ca_system_score_codex":0.00004557047,"about_ca_system_score_gemma":0.00043021183,"threshold_uncertainty_score":0.99983746},"labels":[],"label_agreement":null},{"id":"W3150731771","doi":"10.1080/14728222.2021.1915993","title":"Targeting neuroprotective functions of astrocytes in neuroimmune diseases","year":2021,"lang":"en","type":"editorial","venue":"Expert Opinion on Therapeutic Targets","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neuroprotection; Neuroscience; Central nervous system; Astrocyte; Homeostasis; Neuroinflammation; Biology; Nervous system; Medicine; Immunology; Inflammation; Cell biology","score_opus":0.028793374270692056,"score_gpt":0.29636115746779407,"score_spread":0.267567783197102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3150731771","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003958236,0.009749146,0.001471646,0.00055660773,0.98540795,0.0011989415,0.00043506658,0.00033913163,0.00044567185],"genre_scores_gemma":[0.071731836,0.04254559,0.0004108811,0.0050417488,0.87246656,0.0013476097,0.0019834272,0.0009212749,0.003551043],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948197,0.0011872853,0.0009362126,0.0013052695,0.0012524913,0.00049903715],"domain_scores_gemma":[0.9967127,0.0016098175,0.0006128605,0.00071892183,0.00021126693,0.0001344488],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017649608,0.00060919044,0.00071278925,0.0004874429,0.0002594697,0.00011256137,0.0005302873,0.00036150395,0.00041106468],"category_scores_gemma":[0.0025691015,0.00060629327,0.0002699272,0.0006242246,0.00011829495,0.00022233778,0.00015320227,0.0011307815,0.00007065983],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039606623,0.0005525582,0.0000023346556,0.00005414373,0.000016949285,0.000057955483,0.0003828489,0.0010454854,0.70435894,0.00062070886,0.28856236,0.003949635],"study_design_scores_gemma":[0.0008430659,0.00042091325,0.000020180218,0.00011157123,0.0000043586488,0.0000027849715,0.00007110419,0.0006042266,0.3762314,0.00006859386,0.6212304,0.00039136026],"about_ca_topic_score_codex":0.0000113146225,"about_ca_topic_score_gemma":0.0000017993151,"teacher_disagreement_score":0.33266807,"about_ca_system_score_codex":0.000094416406,"about_ca_system_score_gemma":0.00032733422,"threshold_uncertainty_score":0.99963886},"labels":[],"label_agreement":null},{"id":"W3202456313","doi":"10.1080/14728222.2021.1989410","title":"Transglutaminase 2 as a therapeutic target for neurological conditions","year":2021,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Blood properties and coagulation","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Tissue transglutaminase; Context (archaeology); Multiple sclerosis; Disease; Mechanism (biology); Medicine; Neurodegeneration; Amyotrophic lateral sclerosis; Neuroscience; Bioinformatics; Biology; Pathology; Immunology; Enzyme; Biochemistry","score_opus":0.11639714725605277,"score_gpt":0.4058020030625831,"score_spread":0.28940485580653036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202456313","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000017940898,0.9914674,0.0009211057,0.0023166686,0.001527774,0.0029847252,0.000127291,0.00019576853,0.00045743535],"genre_scores_gemma":[0.00027488146,0.9866153,0.00046578376,0.0063276207,0.0010662334,0.0018518703,0.0024688675,0.00018651194,0.00074295525],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99676985,0.0003862554,0.00082569406,0.00096947234,0.00044216146,0.0006065664],"domain_scores_gemma":[0.99821806,0.00033401218,0.00027063073,0.0007592152,0.00016149196,0.00025659485],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022289858,0.00078684196,0.002220615,0.00021549356,0.0003233427,0.00006755401,0.00025797845,0.00073336146,0.0016604642],"category_scores_gemma":[0.000053252395,0.0005544696,0.0014284692,0.00029254626,0.00012435747,0.00006928457,0.000033799097,0.0006239786,0.00014990142],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022959763,0.0007524046,9.0038947e-7,0.0015471284,0.0007656798,0.000029852547,0.00029617883,0.0000019526642,0.000016797272,0.0035872427,0.0022205743,0.9905517],"study_design_scores_gemma":[0.001332075,0.0029186888,0.0000069181006,0.0029620035,0.00034832017,0.0002703255,0.000078883895,0.000112840185,0.000038278045,0.00051910145,0.9908461,0.0005664767],"about_ca_topic_score_codex":0.0000046520067,"about_ca_topic_score_gemma":3.2327452e-7,"teacher_disagreement_score":0.9899852,"about_ca_system_score_codex":0.000089003915,"about_ca_system_score_gemma":0.00048943603,"threshold_uncertainty_score":0.99969065},"labels":[],"label_agreement":null},{"id":"W3212524944","doi":"10.1080/14728222.2021.2006186","title":"Emerging therapeutic targets for idiopathic pulmonary fibrosis: preclinical progress and therapeutic implications","year":2021,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Medicine; Idiopathic pulmonary fibrosis; Disease; Clinical trial; Drug development; Therapeutic approach; Drug; Precision medicine; Bioinformatics; Intensive care medicine; Lung; Pharmacology; Internal medicine; Pathology; Biology","score_opus":0.07511358586126267,"score_gpt":0.40445285585001606,"score_spread":0.3293392699887534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3212524944","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000011621065,0.9887397,0.0008352487,0.002685214,0.0021133581,0.004725427,0.00036911253,0.00031976344,0.00021099388],"genre_scores_gemma":[0.0028095413,0.9850306,0.00052790705,0.0023430898,0.00259474,0.0043405974,0.001660838,0.00042253037,0.00027019193],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.993438,0.00069602224,0.0018704972,0.0020832282,0.00068698503,0.0012252489],"domain_scores_gemma":[0.9960718,0.0006333866,0.0008015075,0.001470935,0.00038410779,0.00063823874],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0007137444,0.0015017359,0.003623668,0.00043465273,0.00068111194,0.000187329,0.0005994148,0.0011251674,0.00021011475],"category_scores_gemma":[0.00008393231,0.0012038873,0.0021598593,0.00051706284,0.00043959942,0.00015987553,0.00020901661,0.0011102001,0.000047916874],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010176958,0.001247732,0.000018572391,0.0071382592,0.0014467229,0.00002955165,0.0003528712,5.1159816e-7,0.000059949434,0.003284993,0.0006899051,0.98471326],"study_design_scores_gemma":[0.0009620732,0.0032575212,0.00008394117,0.02173001,0.0009852236,0.0004276063,0.00019102302,0.00023431182,0.00001809334,0.00071025296,0.9701938,0.0012061581],"about_ca_topic_score_codex":0.0000064824203,"about_ca_topic_score_gemma":4.9135934e-7,"teacher_disagreement_score":0.9835071,"about_ca_system_score_codex":0.00034679606,"about_ca_system_score_gemma":0.0009564277,"threshold_uncertainty_score":0.99977314},"labels":[],"label_agreement":null},{"id":"W3212864445","doi":"10.1080/14728222.2021.2008907","title":"<i>Clostridioides difficile</i>: innovations in target discovery and potential for therapeutic success","year":2021,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; National Institute for Health and Care Research","keywords":"Clostridioides; Medicine; Drug discovery; Clinical trial; Drug; Intensive care medicine; Bioinformatics; Biology; Pharmacology","score_opus":0.035262177614949104,"score_gpt":0.3356124338975195,"score_spread":0.3003502562825704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3212864445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7139658,0.20301017,0.014938507,0.056667596,0.003716152,0.004495575,0.0004666625,0.00038062618,0.0023589071],"genre_scores_gemma":[0.9853623,0.0090178065,0.0005711567,0.0029709686,0.00064367254,0.0002683553,0.000465436,0.00008198942,0.0006183454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99726987,0.00012771424,0.000579526,0.0007656498,0.0005634803,0.00069378066],"domain_scores_gemma":[0.99858195,0.00031163037,0.00010146924,0.00052711746,0.0002984561,0.00017940783],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002908257,0.00038645824,0.00057993195,0.00033247005,0.00023516525,0.00015145987,0.00016523042,0.00022619581,0.0001999374],"category_scores_gemma":[0.00013072384,0.0003426429,0.00019725676,0.00069420633,0.00015296935,0.00020627015,0.000093026996,0.00042965895,0.000013539756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004830089,0.005163137,0.0064962693,0.00039360544,0.00080634654,0.00025666435,0.0018952892,0.00025674197,0.8253324,0.020079851,0.0061152535,0.12837435],"study_design_scores_gemma":[0.011225859,0.0017259172,0.015462341,0.0004030879,0.00003931573,0.00021719461,0.0018522759,0.003386993,0.7391366,0.0024041221,0.22309358,0.0010527141],"about_ca_topic_score_codex":0.00003594559,"about_ca_topic_score_gemma":0.0000071236536,"teacher_disagreement_score":0.27139646,"about_ca_system_score_codex":0.00019362311,"about_ca_system_score_gemma":0.00043233932,"threshold_uncertainty_score":0.99990255},"labels":[],"label_agreement":null},{"id":"W4214592576","doi":"10.1080/14728222.2022.2047178","title":"Calpain as a therapeutic target in cancer","year":2022,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Calpain; Cancer; Medicine; Cancer research; Biology; Computational biology; Pharmacology; Internal medicine; Biochemistry; Enzyme","score_opus":0.06370134639848704,"score_gpt":0.3783406912926034,"score_spread":0.3146393448941164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214592576","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000014454707,0.9950838,0.00028740976,0.00025839952,0.0023389112,0.0012421844,0.000045580306,0.000047071608,0.0006951994],"genre_scores_gemma":[0.00007340156,0.99122244,0.0000469081,0.002683161,0.00088335725,0.001887922,0.001327113,0.00014279937,0.0017329023],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968308,0.000793464,0.0006026971,0.00091174635,0.00039339103,0.0004678709],"domain_scores_gemma":[0.99881804,0.00007394815,0.0002970131,0.0006554826,0.000029831499,0.00012571135],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00043682774,0.0006140385,0.00084894017,0.0002787197,0.00018341506,0.000036072182,0.00039105004,0.000537252,0.0033244425],"category_scores_gemma":[0.00003785573,0.000514068,0.0005510083,0.00033042743,0.00007349786,0.000005412973,0.0001238901,0.0005007778,0.000072517876],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012961203,0.00026261702,0.0000037712887,0.00033186967,0.00024155734,0.0000048761153,0.00013481101,0.00004188415,0.00017664518,0.00030836838,0.0033667309,0.99499726],"study_design_scores_gemma":[0.0005088959,0.00041549935,0.00000562476,0.0005353095,0.000016397047,0.000022309756,0.000059901457,0.000037974012,0.00013060516,0.00015592069,0.99750376,0.0006078035],"about_ca_topic_score_codex":0.00007357653,"about_ca_topic_score_gemma":0.000009865546,"teacher_disagreement_score":0.9943895,"about_ca_system_score_codex":0.00026582342,"about_ca_system_score_gemma":0.0005009983,"threshold_uncertainty_score":0.99973106},"labels":[],"label_agreement":null},{"id":"W4306315302","doi":"10.1080/14728222.2022.2137020","title":"The molecular mechanisms and targeting strategies of transcription factors in cholangiocarcinoma","year":2022,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Cholangiocarcinoma and Gallbladder Cancer Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Transcription factor; Cancer research; Biology; Epigenetics; KRAS; Carcinogenesis; Intrahepatic Cholangiocarcinoma; Malignancy; Transcription (linguistics); Bioinformatics; Cancer; Medicine; Internal medicine; Genetics; Gene; Colorectal cancer","score_opus":0.06819705147010136,"score_gpt":0.34751116145624517,"score_spread":0.2793141099861438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306315302","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000052079402,0.99745035,0.00007974107,0.00017916202,0.0007885929,0.00095074845,0.000019593606,0.000038068596,0.0004416808],"genre_scores_gemma":[0.0096668685,0.98954374,0.00006526499,0.00012740045,0.000087741086,0.00025652428,0.00015504494,0.00007336592,0.000024041152],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99778783,0.0002781046,0.0006423548,0.00048622818,0.00044155808,0.0003639449],"domain_scores_gemma":[0.99898654,0.00027551298,0.00026336187,0.00037003678,0.000029725095,0.00007482674],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033021238,0.00048244678,0.001255827,0.00023936582,0.00021221829,0.0000407704,0.0002080449,0.00017597114,0.000082246625],"category_scores_gemma":[0.00002692343,0.00030882243,0.00045664454,0.0002730931,0.00010719672,0.00006545889,0.000064690306,0.00053538114,0.0000015622837],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014769248,0.0002595991,0.00005195062,0.0029977844,0.0008524522,0.00003797242,0.0057205125,0.0000019466738,0.00047000594,0.012319146,0.00028848182,0.9768525],"study_design_scores_gemma":[0.00059502426,0.0005218638,0.00036093386,0.0013158668,0.00008231862,0.000019800113,0.0044256365,0.000005472949,0.00012656466,0.0003323694,0.9919316,0.0002825299],"about_ca_topic_score_codex":0.000069121124,"about_ca_topic_score_gemma":0.000005046186,"teacher_disagreement_score":0.99164313,"about_ca_system_score_codex":0.00016999178,"about_ca_system_score_gemma":0.00019025177,"threshold_uncertainty_score":0.9999364},"labels":[],"label_agreement":null},{"id":"W4313877335","doi":"10.1080/14728222.2022.2166830","title":"DDX3: a relevant therapeutic target for lymphoma?","year":2022,"lang":"en","type":"editorial","venue":"Expert Opinion on Therapeutic Targets","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Lymphoma; Cancer research; Medicine; Computational biology; Biology; Immunology","score_opus":0.015125440634053888,"score_gpt":0.3009397313811786,"score_spread":0.28581429074712467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313877335","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000025260124,0.20085268,0.003912727,0.0007888086,0.7915434,0.0016438765,0.000704848,0.00012185761,0.0004065336],"genre_scores_gemma":[0.0036136985,0.030105742,0.0010167346,0.0017275768,0.93170303,0.0026824567,0.023706246,0.00064855843,0.004795981],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.995893,0.00029066272,0.00066209474,0.0014497202,0.00094548694,0.00075906154],"domain_scores_gemma":[0.9976177,0.00025238973,0.00049847836,0.0012134742,0.00026230674,0.00015561197],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00048026475,0.00081017386,0.00063789176,0.00020212114,0.000430645,0.00007499108,0.0007422897,0.0014191752,0.0004689152],"category_scores_gemma":[0.00016082003,0.00081003085,0.0005503026,0.00017987283,0.0001110237,0.0000083885225,0.0001864587,0.00042403408,0.000030930612],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015920018,0.0002655631,0.0000012481019,0.000043209155,0.0006059564,0.0000012171855,0.00020204534,0.00026937766,0.017282141,0.00015167905,0.9200713,0.059514266],"study_design_scores_gemma":[0.002711013,0.002324026,0.000009033476,0.00005119165,0.000025072826,0.0000051638835,0.00007375218,0.00020694167,0.013840262,0.0007145758,0.97910815,0.000930794],"about_ca_topic_score_codex":0.000027409102,"about_ca_topic_score_gemma":0.000006827561,"teacher_disagreement_score":0.17074694,"about_ca_system_score_codex":0.0004401104,"about_ca_system_score_gemma":0.00085743994,"threshold_uncertainty_score":0.9998772},"labels":[],"label_agreement":null},{"id":"W4315928178","doi":"10.1080/14728222.2022.2168188","title":"Targeting BMPR-II in pulmonary arterial hypertension: a case of Hercules versus the Hydra?","year":2022,"lang":"en","type":"editorial","venue":"Expert Opinion on Therapeutic Targets","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Lernaean Hydra; Pulmonary hypertension; Medicine; Cardiology; Internal medicine; Biology; Cell biology","score_opus":0.045184825970907797,"score_gpt":0.3391770330565959,"score_spread":0.29399220708568813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315928178","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007524553,0.12742673,0.0000023025007,0.0038012508,0.8571394,0.002423863,0.00042081648,0.00012889967,0.001132164],"genre_scores_gemma":[0.31236857,0.044244286,0.00033022856,0.0018434714,0.6310366,0.0015785209,0.006648469,0.0005066087,0.0014432506],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950207,0.00063228427,0.0008600998,0.0009967446,0.0016799137,0.00081029895],"domain_scores_gemma":[0.9964641,0.0015807493,0.00033847836,0.0010715565,0.0002766472,0.00026851273],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006494058,0.0007041037,0.0011953688,0.00041357093,0.00060525193,0.000028313567,0.00044346848,0.00063021126,0.0015554464],"category_scores_gemma":[0.00058596715,0.00047034613,0.00042027744,0.00043049632,0.00023458705,0.000099533914,0.00038686558,0.0016238654,0.00003959715],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021258684,0.0045292284,0.000030278157,0.00012555577,0.0009857676,0.035659075,0.0009200074,0.000026819875,0.005014373,0.00003296049,0.9090664,0.022350892],"study_design_scores_gemma":[0.0065480703,0.0030032233,0.00007086764,0.00025759602,0.000046559766,0.0011522672,0.001284138,0.0007424558,0.00018069483,0.000053914533,0.9862247,0.00043551176],"about_ca_topic_score_codex":0.0007002116,"about_ca_topic_score_gemma":0.000013034612,"teacher_disagreement_score":0.30484402,"about_ca_system_score_codex":0.00039429724,"about_ca_system_score_gemma":0.00065629155,"threshold_uncertainty_score":0.9997748},"labels":[],"label_agreement":null},{"id":"W4322617172","doi":"10.1080/14728222.2023.2185133","title":"Emerging therapeutic targets for osteoarthritis","year":2023,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Osteoarthritis; Medicine; Disease; Clinical trial; Bioinformatics; Pathology; Biology; Alternative medicine","score_opus":0.09265214984559993,"score_gpt":0.38927130186090697,"score_spread":0.29661915201530703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322617172","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[2.641624e-7,0.98514646,0.0003203463,0.00039342867,0.0063164765,0.0060617905,0.00025206854,0.0007613992,0.00074773625],"genre_scores_gemma":[0.000011949268,0.9845193,0.0006442339,0.0013482778,0.0024009096,0.0039532525,0.0030212288,0.0006148761,0.0034859444],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9952232,0.00024052731,0.0012032271,0.0013826437,0.00071889535,0.0012314672],"domain_scores_gemma":[0.997279,0.00056790985,0.0005053225,0.001094892,0.00015374136,0.00039915653],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00039285686,0.0013541041,0.0031674083,0.0006645397,0.00041307928,0.00009230952,0.00039815914,0.0008473462,0.00054891984],"category_scores_gemma":[0.00006184496,0.0010927385,0.0018351723,0.0004972953,0.0001011736,0.0001209312,0.00008819452,0.00060708914,0.0010868104],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019242606,0.00029242111,3.4696038e-7,0.0025481435,0.00070227956,0.00006434014,0.0004717786,1.473661e-7,0.00003263019,0.002346472,0.002209244,0.99113977],"study_design_scores_gemma":[0.003941349,0.0050972593,4.9092824e-7,0.012091382,0.00033529958,0.00016225912,0.00015191355,0.000007771773,0.00013309174,0.00075622986,0.97635895,0.00096401153],"about_ca_topic_score_codex":0.0000038253697,"about_ca_topic_score_gemma":0.0000033320055,"teacher_disagreement_score":0.9901758,"about_ca_system_score_codex":0.00032932885,"about_ca_system_score_gemma":0.00042341996,"threshold_uncertainty_score":0.99992096},"labels":[],"label_agreement":null},{"id":"W4328048316","doi":"10.1080/14728222.2023.2185511","title":"Parasite and host kinases as targets for antimalarials","year":2023,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Malaria Research and Control","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; Genentech; Ontario Genomics Institute; RMIT University; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; National Institutes of Health; Ontario Genomics; Genome Canada; McGill University; National Institute of Allergy and Infectious Diseases; Medical Research Council; Bayer; State Government of Victoria; Pfizer; Bristol-Myers Squibb","keywords":"Druggability; Kinase; Biology; Drug discovery; Kinome; Drug resistance; Plasmodium falciparum; Malaria; Computational biology; Bioinformatics; Cell biology; Immunology; Genetics; Gene","score_opus":0.12460516986616908,"score_gpt":0.44392775970695103,"score_spread":0.31932258984078193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4328048316","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[4.371934e-7,0.9900751,0.0002026646,0.0026174884,0.0012386004,0.005004403,0.00017004214,0.00022021076,0.00047106802],"genre_scores_gemma":[0.00004046455,0.9921781,0.00022737333,0.0015239095,0.0017466916,0.0019411775,0.0005759587,0.00021976767,0.0015465781],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99645144,0.00031758225,0.00078139,0.000964674,0.00061006995,0.0008748289],"domain_scores_gemma":[0.99720925,0.0011532293,0.0003128251,0.0007118327,0.00015265646,0.00046020353],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006821859,0.0007544615,0.002572771,0.0004543015,0.00024549858,0.00010881825,0.00028859658,0.000560361,0.0003969917],"category_scores_gemma":[0.00054869946,0.00054435903,0.0007390761,0.00027866315,0.00010091415,0.00007657995,0.000090388836,0.00049466867,0.00044335218],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007730849,0.00027953536,0.0000027183437,0.0062744925,0.0014381513,0.00006800436,0.00014625269,5.872303e-8,0.00007800482,0.0055639227,0.009121286,0.97625446],"study_design_scores_gemma":[0.0021278197,0.0015524913,0.00004517319,0.0063184095,0.00015335923,0.000073294534,0.000033951637,0.000025969508,0.00006530565,0.00027856775,0.98881876,0.0005069023],"about_ca_topic_score_codex":0.00003811066,"about_ca_topic_score_gemma":0.0000015882337,"teacher_disagreement_score":0.97969747,"about_ca_system_score_codex":0.00011033199,"about_ca_system_score_gemma":0.0005297165,"threshold_uncertainty_score":0.9997008},"labels":[],"label_agreement":null},{"id":"W4381164454","doi":"10.1080/14728222.2023.2199923","title":"Human prion disease: molecular pathogenesis, and possible therapeutic targets and strategies","year":2023,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Health, British Columbia; Ministero della Salute","keywords":"Pathogenesis; Disease; Biology; Medicine; Computational biology; Immunology; Neuroscience; Pathology","score_opus":0.020405905373508237,"score_gpt":0.3104624357681918,"score_spread":0.2900565303946836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381164454","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23132397,0.7642442,0.0015679527,0.0013391086,0.0004231355,0.00072039623,0.000057498502,0.00017464117,0.00014911921],"genre_scores_gemma":[0.94953203,0.04820652,0.00011738818,0.0013849022,0.00021088528,0.00011747189,0.00026578864,0.00006144847,0.00010353958],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983628,0.00014877638,0.00022265046,0.00062732777,0.00023068665,0.00040778352],"domain_scores_gemma":[0.99920166,0.000016525917,0.0000828639,0.0004064778,0.000044264234,0.00024821018],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019049105,0.0003159359,0.00020037722,0.000101546764,0.00031705454,0.00012643181,0.00017586746,0.00014598444,0.00005254322],"category_scores_gemma":[0.000015149992,0.00028688367,0.000100073215,0.00012839629,0.00014131523,0.000017376187,0.00013455037,0.00009197889,0.000012423409],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001939276,0.000093922885,0.00075664424,0.00004939513,0.00013031783,0.00001623611,0.0002709838,0.00006004173,0.877686,0.0044776546,0.0006038003,0.11566107],"study_design_scores_gemma":[0.0044041597,0.0022585758,0.1666759,0.00027415724,0.000060695937,0.000033423898,0.0020100356,0.0011892274,0.1944843,0.023436587,0.60251194,0.0026609786],"about_ca_topic_score_codex":0.00000727063,"about_ca_topic_score_gemma":0.0000010871448,"teacher_disagreement_score":0.7182081,"about_ca_system_score_codex":0.000013332497,"about_ca_system_score_gemma":0.000073379335,"threshold_uncertainty_score":0.99995834},"labels":[],"label_agreement":null},{"id":"W4382048782","doi":"10.1080/14728222.2023.2230364","title":"SCN1A as a therapeutic target for Dravet syndrome","year":2023,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Montreal Children's Hospital","funders":"","keywords":"Dravet syndrome; Medicine; Epilepsy; Pediatrics; Encephalopathy; Epilepsy syndromes; Sodium channel blocker; Disease; Bioinformatics; Sodium channel; Psychiatry; Internal medicine; Biology","score_opus":0.15794953117738397,"score_gpt":0.45185998624971424,"score_spread":0.29391045507233027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382048782","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[6.1057386e-7,0.9884941,0.00019782128,0.0011687031,0.0017804515,0.006606268,0.00023515019,0.00047712086,0.0010397492],"genre_scores_gemma":[0.00004745058,0.98437995,0.0005012048,0.0014402618,0.0008537099,0.0047863796,0.002269313,0.0004815075,0.005240236],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99494463,0.00036126518,0.0010166503,0.0013268614,0.0010174054,0.0013331631],"domain_scores_gemma":[0.9965104,0.0010033206,0.0003610612,0.0013264276,0.00016646361,0.00063236966],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005744071,0.0011782479,0.003147616,0.0007227389,0.00032218144,0.00009827825,0.00052175426,0.00071942783,0.0009600784],"category_scores_gemma":[0.000118519914,0.00081784383,0.0017232749,0.0006138737,0.00016046574,0.00007636467,0.0001020121,0.0007799885,0.0036355767],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040329056,0.000901431,0.0000041190547,0.0061201393,0.003968054,0.00028241315,0.00025364218,3.05181e-7,0.0000032827988,0.0023414535,0.0060814787,0.97964036],"study_design_scores_gemma":[0.0021484846,0.005459569,0.000013416448,0.009340883,0.00021946055,0.00048350127,0.00006477815,0.000020178639,0.000018202096,0.001939058,0.9795946,0.0006978827],"about_ca_topic_score_codex":0.000028541454,"about_ca_topic_score_gemma":0.0000012155493,"teacher_disagreement_score":0.9789425,"about_ca_system_score_codex":0.00056753727,"about_ca_system_score_gemma":0.0010926519,"threshold_uncertainty_score":0.99995315},"labels":[],"label_agreement":null},{"id":"W4385262311","doi":"10.1080/14728222.2023.2240018","title":"Targets for obstructive sleep apnea pharmacotherapy: principles, approaches, and emerging strategies","year":2023,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Obstructive Sleep Apnea Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Sanitarium Association","keywords":"Medicine; Obstructive sleep apnea; Dilator; Pharmacotherapy; Pharyngeal muscles; Intensive care medicine; Neuroscience; Bioinformatics; Airway; Anesthesia; Internal medicine; Psychology","score_opus":0.1982236052926008,"score_gpt":0.4225220442694087,"score_spread":0.2242984389768079,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385262311","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000017499078,0.98722345,0.0031207975,0.0003832886,0.0019082475,0.0059901946,0.00021260144,0.00040279,0.00075685856],"genre_scores_gemma":[0.000075287026,0.9912656,0.002092698,0.00023980458,0.0016782641,0.00277775,0.0008946683,0.0005447952,0.00043112654],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9946366,0.00041836392,0.0011169548,0.0016846216,0.0009148229,0.0012286216],"domain_scores_gemma":[0.99714243,0.00076743914,0.00055429654,0.0008749856,0.00020320498,0.0004576457],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006845863,0.0012705409,0.002716843,0.0008208159,0.00040597242,0.00016851898,0.00051234657,0.0006530391,0.00018899122],"category_scores_gemma":[0.000099204175,0.0010108919,0.0008242822,0.00062857073,0.0003588351,0.00023858319,0.00019255817,0.001104141,0.00007445465],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003439178,0.00023577092,0.0000030664173,0.0074761845,0.0027214172,0.000018903542,0.0012241912,0.000005841304,0.00005956548,0.0067352657,0.00023139363,0.98094445],"study_design_scores_gemma":[0.0021872162,0.0005959665,0.000020294452,0.0019489385,0.00019460582,0.000079643396,0.0012293925,0.0016074065,0.000118559765,0.00054104446,0.99056387,0.00091303623],"about_ca_topic_score_codex":0.000012928732,"about_ca_topic_score_gemma":0.000001283119,"teacher_disagreement_score":0.9903325,"about_ca_system_score_codex":0.00048633188,"about_ca_system_score_gemma":0.00031927408,"threshold_uncertainty_score":0.99923414},"labels":[],"label_agreement":null},{"id":"W4386316190","doi":"10.1080/14728222.2023.2247559","title":"New drug targets for the treatment of gout arthritis: what’s new?","year":2023,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Gout, Hyperuricemia, Uric Acid","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Health, British Columbia","keywords":"Medicine; Disease; Repurposing; Gout; Drug repositioning; Drug; Clinical trial; Arthritis; Intensive care medicine; Population; Approved drug; Bioinformatics; Pharmacology; Immunology; Internal medicine; Biology","score_opus":0.11531728934831652,"score_gpt":0.39513972017679544,"score_spread":0.2798224308284789,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386316190","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[2.0204581e-7,0.9826272,0.00089696766,0.003235776,0.0071287975,0.0056459866,0.00008010511,0.00026539149,0.00011955041],"genre_scores_gemma":[0.0000029248145,0.98118424,0.0012325221,0.0010062911,0.004217826,0.001133742,0.000507342,0.0003625544,0.010352577],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9957315,0.0001955265,0.0013771236,0.0010528893,0.0008001566,0.0008428566],"domain_scores_gemma":[0.9956613,0.0013786667,0.0007379122,0.0016539828,0.000109876324,0.00045822404],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032167564,0.0011497447,0.0031967487,0.00033781532,0.00021260082,0.00009169519,0.0005822155,0.00055612944,0.00047091578],"category_scores_gemma":[0.00008300886,0.00069505785,0.0018248699,0.00049080304,0.00010976392,0.00015105974,0.00006155734,0.00040065174,0.0004412147],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000157621,0.00038593131,6.1063565e-7,0.0010542826,0.0023083412,0.0000134424,0.003169314,0.0000015741389,0.000003561959,0.0002146152,0.05939569,0.933295],"study_design_scores_gemma":[0.0030450693,0.0016178918,0.0000056337767,0.011168477,0.00053315784,0.00006724263,0.0005968041,0.00002080328,0.00009196957,0.00021717456,0.98206097,0.00057478395],"about_ca_topic_score_codex":0.00022739725,"about_ca_topic_score_gemma":0.000011127384,"teacher_disagreement_score":0.93272024,"about_ca_system_score_codex":0.00053725095,"about_ca_system_score_gemma":0.0013704561,"threshold_uncertainty_score":0.99955004},"labels":[],"label_agreement":null},{"id":"W4399300458","doi":"10.1080/14728222.2024.2362675","title":"Novel benzimidazole angiotensin receptor blockers with anti-SARS-CoV-2 activity equipotent to that of nirmatrelvir: computational and enzymatic studies","year":2024,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Candesartan; Losartan; Benzimidazole; Tetrazole; Medicine; Pharmacology; Renin–angiotensin system; Angiotensin II; Angiotensin II receptor antagonist; Receptor; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Angiotensin-converting enzyme 2; Coronavirus disease 2019 (COVID-19); Internal medicine; Chemistry; Blood pressure; Disease; Stereochemistry","score_opus":0.1325843056078143,"score_gpt":0.4454472802360098,"score_spread":0.3128629746281955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399300458","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5648521,0.12195764,0.025755158,0.27992627,0.0023790938,0.004222528,0.00018179284,0.000631958,0.0000934489],"genre_scores_gemma":[0.9851798,0.0037842074,0.00640358,0.0043029925,0.00016019856,0.000066885266,0.00001369908,0.00004625251,0.00004240199],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978422,0.00008180174,0.00033752527,0.00055090094,0.0008164392,0.0003711691],"domain_scores_gemma":[0.99688107,0.0023845225,0.000084720166,0.00028993565,0.00022233377,0.00013743334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003995113,0.0003058831,0.00067146163,0.00026325957,0.00012460568,0.000032932527,0.000105534,0.00008364331,0.000017884657],"category_scores_gemma":[0.0005824743,0.00020865395,0.00013633148,0.00032549934,0.0003241375,0.00010172822,0.00015537556,0.00026674234,0.00002795372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005714544,0.0031530312,0.0022086438,0.00277092,0.008395705,0.000085125794,0.027301127,0.0017327046,0.70123464,0.0018613747,0.04165559,0.20388661],"study_design_scores_gemma":[0.012729409,0.013696584,0.04913255,0.010289726,0.00027287204,0.000075078104,0.0039124927,0.05869478,0.45494255,0.0014949731,0.39262003,0.0021389513],"about_ca_topic_score_codex":0.00004790757,"about_ca_topic_score_gemma":0.000003331031,"teacher_disagreement_score":0.42032766,"about_ca_system_score_codex":0.00018054993,"about_ca_system_score_gemma":0.00019019094,"threshold_uncertainty_score":0.8508661},"labels":[],"label_agreement":null},{"id":"W4409922316","doi":"10.1080/14728222.2025.2500424","title":"The sigma–1 receptor: a mechanistically–informed therapeutic target for antidepressants","year":2025,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Ottawa; University Health Network; Brain and Cognition Discovery Foundation; Queen's University","funders":"","keywords":"Sigma-1 receptor; Pharmacology; Receptor; Medicine; Chemistry; Bioinformatics; Internal medicine; Biology; Agonist","score_opus":0.04978324787557406,"score_gpt":0.39410660911828854,"score_spread":0.34432336124271445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409922316","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[1.3044368e-7,0.97557026,0.015219085,0.00027965716,0.004819187,0.0029747025,0.00037887177,0.000061263374,0.00069681683],"genre_scores_gemma":[0.000048429967,0.9904784,0.00083416747,0.0024094472,0.0011739461,0.0025360303,0.0013949323,0.00012174735,0.0010028839],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99623364,0.0005117384,0.0007981909,0.0010586783,0.0003999473,0.0009978021],"domain_scores_gemma":[0.9969485,0.0013691277,0.00041652005,0.00088243146,0.00015109817,0.00023235558],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007073212,0.00094113784,0.0012737266,0.00011230302,0.00066778646,0.00019600731,0.0012313537,0.0010053071,0.00020053335],"category_scores_gemma":[0.0005533223,0.00057523063,0.0010607906,0.00020892033,0.00014045993,0.000007972665,0.00025626516,0.00048400884,0.000037250593],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038126373,0.00016351217,5.794353e-8,0.0011107045,0.00070407917,8.279506e-7,0.000019964506,0.0000024955884,0.0020166093,0.0054382356,0.028011365,0.9621509],"study_design_scores_gemma":[0.00077686866,0.0012508528,1.3345957e-7,0.0014060427,0.00006976301,0.000004599104,0.000020035552,0.00004515627,0.0051138117,0.0014291161,0.9892,0.0006836182],"about_ca_topic_score_codex":0.0000021265187,"about_ca_topic_score_gemma":0.0000012337459,"teacher_disagreement_score":0.96146727,"about_ca_system_score_codex":0.00011606916,"about_ca_system_score_gemma":0.00063888816,"threshold_uncertainty_score":0.9996699},"labels":[],"label_agreement":null},{"id":"W4413910481","doi":"10.1080/14728222.2025.2552324","title":"Role of serotonin in the neurobiology of attention-deficit/hyperactivity disorder: a systematic literature review","year":2025,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Otsuka Pharmaceutical Development and Commercialization; Otsuka Pharmaceutical","keywords":"Attention deficit hyperactivity disorder; Neuroscience; Serotonin; Psychology; Attention deficit; Psychiatry; Medicine; Internal medicine","score_opus":0.038140994516687496,"score_gpt":0.3728871866859787,"score_spread":0.3347461921692912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413910481","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000053914282,0.991696,0.000021336262,0.00058546616,0.000385882,0.0068191504,0.00007601504,0.00003409394,0.00032816638],"genre_scores_gemma":[0.00087192375,0.9963797,0.000033161115,0.0006806011,0.00005645864,0.0013546424,0.00043339535,0.00006309579,0.00012703778],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.99428993,0.0024182114,0.0017225943,0.000671188,0.00053917296,0.00035890742],"domain_scores_gemma":[0.99550027,0.0015820276,0.0012994767,0.0013512222,0.00021598437,0.000051016137],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008882089,0.00070331414,0.00436848,0.0005576114,0.00006837888,0.00001753172,0.0005267507,0.0004944312,0.000093710296],"category_scores_gemma":[0.00043254494,0.00042884765,0.0012476614,0.0012851806,0.00011000915,0.00009944578,0.00008369102,0.0009982139,0.00002596495],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076348544,0.0021345047,0.00028305702,0.84374654,0.0006210995,0.000007736207,0.0003440379,0.0000011597762,0.000054510594,0.0007640305,0.000105055726,0.15186192],"study_design_scores_gemma":[0.0007431586,0.0004005148,0.0003524411,0.74133486,0.0004878267,0.00014544836,0.00054561265,0.000010130198,0.0000014470573,0.000017882585,0.25559264,0.00036807903],"about_ca_topic_score_codex":0.000015233149,"about_ca_topic_score_gemma":0.0000037448337,"teacher_disagreement_score":0.25548756,"about_ca_system_score_codex":0.00008577337,"about_ca_system_score_gemma":0.00029402005,"threshold_uncertainty_score":0.99981636},"labels":[],"label_agreement":null},{"id":"W4417534740","doi":"10.1080/14728222.2025.2608031","title":"Harnessing mismatch repair deficiency for therapeutic targeting in cancers","year":2025,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Targets","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Rally Foundation; U.S. Department of Defense","keywords":"DNA mismatch repair; Immune system; Biomarker; Cancer; Tumor microenvironment; Genome instability; Cancer treatment; Microsatellite instability","score_opus":0.03535287086509377,"score_gpt":0.3513386484449475,"score_spread":0.31598577757985374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417534740","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1017953,0.8032801,0.022108193,0.025106989,0.021500504,0.008322344,0.000038454113,0.0014622346,0.016385848],"genre_scores_gemma":[0.9836173,0.002159665,0.0040211175,0.008728686,0.00025716439,0.0005677381,0.000033017583,0.00006684528,0.0005484614],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99767476,0.00010424713,0.00054749474,0.0006865585,0.00034381106,0.0006431207],"domain_scores_gemma":[0.99888384,0.00031546195,0.00011962222,0.00045283325,0.00012958319,0.000098641845],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004353064,0.0003518718,0.0004918416,0.00031675427,0.0002013649,0.000031938853,0.000208413,0.0002160142,0.00017533396],"category_scores_gemma":[0.00010817463,0.0003077092,0.0002460305,0.0004976396,0.00011101428,0.000064713844,0.00003925159,0.00030013488,0.000011239644],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008197123,0.0019687542,0.037177444,0.0011634155,0.0008109843,0.000028964501,0.018551974,0.001952777,0.16963351,0.008537337,0.06657268,0.685405],"study_design_scores_gemma":[0.008564471,0.0016855106,0.030454826,0.0014828878,0.000046792265,0.00001537662,0.0036692112,0.013553043,0.06965581,0.0049834074,0.8647612,0.0011274996],"about_ca_topic_score_codex":0.0001117102,"about_ca_topic_score_gemma":0.000013122235,"teacher_disagreement_score":0.881822,"about_ca_system_score_codex":0.0008689517,"about_ca_system_score_gemma":0.0005643919,"threshold_uncertainty_score":0.9999375},"labels":[],"label_agreement":null}]}