{"meta":{"query_hash":"f7a27f2a7244","filters":{"venue":"Gene Therapy"},"cohort_total":173,"direct_labels_cover":0,"predictions_cover":173,"exported":173,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/f7a27f2a7244","api":"https://metacan.xera.ac/api/v1/cohort?venue=Gene+Therapy"},"results":[{"id":"W1489163982","doi":"10.1038/gt.2014.57","title":"Retinal transduction profiles by high-capacity viral vectors","year":2014,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Retinal and Optic Conditions","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Eye Institute","keywords":"Transduction (biophysics); Retinal; Cell biology; Biology; Virology; Chemistry; Biophysics; Biochemistry","score_opus":0.013977816715645103,"score_gpt":0.23634346030788891,"score_spread":0.2223656435922438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1489163982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833272,0.0011003056,0.011635444,0.00009572169,0.00003129944,0.00010220206,0.0005424257,0.000112793736,0.003052654],"genre_scores_gemma":[0.98413384,0.0010333378,0.008141806,0.00005372096,0.000016002967,0.000084850406,0.0012401672,0.00011902,0.005177266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995981,0.0000850952,0.000041989366,0.000057049958,0.000102374586,0.00011553944],"domain_scores_gemma":[0.99967194,0.000119116085,0.00005136514,0.00002537347,0.00007143057,0.000060791972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046372632,0.00037287668,0.00023545371,0.0005849893,0.00025650364,0.0010995714,0.00023466034,0.00043367944,0.0018497222],"category_scores_gemma":[0.0005166587,0.0001615723,0.00029140618,0.00037835393,0.00027406143,0.00062597165,0.00021693711,0.0005640492,0.0006554948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002711899,0.000063775224,0.0003621112,0.000028937817,0.0000052521664,0.000020055884,0.000058311343,0.0001739657,0.99620974,0.00033170712,0.000062992796,0.0024119013],"study_design_scores_gemma":[0.000009050913,0.00038896134,0.0017536703,0.000004626538,0.000021899543,0.00006967723,0.000054727432,0.0011306033,0.99553657,0.000080620455,0.00094090105,0.000008673518],"about_ca_topic_score_codex":0.0021341597,"about_ca_topic_score_gemma":0.0016445747,"teacher_disagreement_score":0.0021341597,"about_ca_system_score_codex":0.00063980336,"about_ca_system_score_gemma":0.00046641062,"threshold_uncertainty_score":0.006187916},"labels":[],"label_agreement":null},{"id":"W1963651436","doi":"10.1038/sj.gt.3302681","title":"Immune response to lentiviral bilirubin UDP-glucuronosyltransferase gene transfer in fetal and neonatal rats","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Neonatal Health and Biochemistry","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Alberta Innovates - Health Solutions","keywords":"Genetic enhancement; Bilirubin; Fetus; Viral vector; Biology; Antibody; Immune system; Immunology; Internal medicine; Gene; Medicine; Endocrinology; Pregnancy; Biochemistry; Genetics","score_opus":0.014369920781640285,"score_gpt":0.2755755714225182,"score_spread":0.2612056506408779,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963651436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99594194,0.00077185954,0.0010565671,0.00016681812,0.00010645654,0.000033478555,0.00033399838,0.000081189166,0.0015076369],"genre_scores_gemma":[0.990721,0.00070703326,0.00069346145,0.00022638195,0.000058220478,0.00009311719,0.00039426476,0.000045885998,0.0070607066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952924,0.00006930246,0.00003669964,0.00010935069,0.000092244496,0.00016318132],"domain_scores_gemma":[0.9993106,0.0001436802,0.00016108032,0.00007578176,0.00006950054,0.00023937691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004147607,0.00065350655,0.00054674345,0.0008816124,0.00026506445,0.0004255899,0.00030212046,0.00057039206,0.002206385],"category_scores_gemma":[0.00045748096,0.00027270787,0.00041590034,0.00021742209,0.0008565444,0.00039872454,0.00027811527,0.0020627414,0.0003944261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002558279,0.00030876,0.0005972343,0.000069860966,0.000011686089,0.00030620417,0.00014449433,0.00012577612,0.99248636,0.00040382732,0.00010599363,0.002881493],"study_design_scores_gemma":[0.00011084625,0.0021471689,0.008533029,0.000025716658,0.000066155306,0.00039788085,0.00040561575,0.00089599384,0.9859239,0.00023805657,0.0012335541,0.000022142141],"about_ca_topic_score_codex":0.0015811868,"about_ca_topic_score_gemma":0.0015826366,"teacher_disagreement_score":0.002206385,"about_ca_system_score_codex":0.000706025,"about_ca_system_score_gemma":0.0005867665,"threshold_uncertainty_score":0.0073810816},"labels":[],"label_agreement":null},{"id":"W1966443498","doi":"10.1038/gt.2010.166","title":"Co-encapsulation of bioengineered IGF-II-producing cells and pancreatic islets: effect on beta-cell survival","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research; Diabète Québec; Canadian Diabetes Association","keywords":"Islet; Acridine orange; Transplantation; Propidium iodide; Pancreatic islets; Biology; Andrology; Molecular biology; In vivo; In vitro; Apoptosis; Endocrinology; Internal medicine; Insulin; Medicine; Biochemistry; Programmed cell death","score_opus":0.027924675375252367,"score_gpt":0.2435448184117,"score_spread":0.21562014303644764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966443498","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99354655,0.0022267269,0.0026600373,0.00005376557,0.000100620266,0.00002009657,0.00013573139,0.000054394983,0.0012020041],"genre_scores_gemma":[0.994189,0.00073336746,0.0024300832,0.000035238634,0.000020961912,0.000029225168,0.00017912986,0.00003915118,0.0023438134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984574,0.000022705737,0.000019219913,0.00003808175,0.000030169505,0.00004414928],"domain_scores_gemma":[0.9998617,0.00004735071,0.00003450723,0.000018265633,0.0000101764645,0.000027954322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020271231,0.00046680466,0.0005085267,0.0001738207,0.00016003884,0.0005856535,0.00019744069,0.0004481637,0.00075122865],"category_scores_gemma":[0.00015381518,0.00017294713,0.0003795148,0.00019850892,0.00025913748,0.0003011522,0.0002629491,0.00046341238,0.00022244795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029807226,0.000032734195,0.00011953681,0.000039014096,0.000010857809,0.000054137145,0.00002222939,0.00014444767,0.997926,0.00006111436,0.000023603157,0.0012682347],"study_design_scores_gemma":[0.000015268326,0.00011080979,0.00048759967,0.0000030372207,0.000016432798,0.000050141087,0.000009025167,0.0002822286,0.9983689,0.0000065693994,0.00064694666,0.0000030222566],"about_ca_topic_score_codex":0.0006515181,"about_ca_topic_score_gemma":0.0007754114,"teacher_disagreement_score":0.00075122865,"about_ca_system_score_codex":0.00026284985,"about_ca_system_score_gemma":0.00019483338,"threshold_uncertainty_score":0.0025131106},"labels":[],"label_agreement":null},{"id":"W1966520413","doi":"10.1038/gt.2010.40","title":"Generation of human TRIM5α mutants with high HIV-1 restriction activity","year":2010,"lang":"en","type":"article","venue":"Gene Therapy","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Center for AIDS Research, University of Washington; Canada Research Chairs; Canadian Institutes of Health Research; University of Alabama at Birmingham","keywords":"Biology; Mutant; Human immunodeficiency virus (HIV); Virology; Lentivirus; Genetics; Genetic enhancement; Gene; Computational biology; Viral disease","score_opus":0.04167233932917241,"score_gpt":0.2928813169860008,"score_spread":0.25120897765682837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966520413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9790795,0.0013674988,0.014488745,0.00020409073,0.00020902987,0.00018812265,0.0022789831,0.00020807995,0.0019759715],"genre_scores_gemma":[0.97529775,0.00067146675,0.015835827,0.00012344669,0.000018916004,0.0001144592,0.0032807905,0.000113058624,0.0045442767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997875,0.000044893604,0.000033157226,0.00003380874,0.000052193245,0.000048522077],"domain_scores_gemma":[0.9998099,0.000033833785,0.000049185357,0.000038693568,0.000026183225,0.00004208258],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003943415,0.00051803084,0.0003584973,0.00022544795,0.00025272783,0.0003993391,0.0005721688,0.00053362036,0.0016522974],"category_scores_gemma":[0.00031303993,0.00023470867,0.0005007488,0.00030229622,0.00024807866,0.00017090587,0.00024300546,0.0009279754,0.0008105399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036977092,0.00008243249,0.00018657176,0.00007066751,0.000031183343,0.00012456767,0.000031008232,0.0005602584,0.99569315,0.00043128396,0.0002646838,0.002154473],"study_design_scores_gemma":[0.000048546623,0.0001561976,0.00047590557,0.000007511619,0.000032543463,0.00032098455,0.000020466423,0.0015559496,0.9936056,0.00005524475,0.0037128145,0.000008169337],"about_ca_topic_score_codex":0.0009898711,"about_ca_topic_score_gemma":0.0007875961,"teacher_disagreement_score":0.0016522974,"about_ca_system_score_codex":0.0005124239,"about_ca_system_score_gemma":0.00025566592,"threshold_uncertainty_score":0.0055274963},"labels":[],"label_agreement":null},{"id":"W1967809163","doi":"10.1038/sj.gt.3302587","title":"Gene delivery to human sweat glands: a model for cystic fibrosis gene therapy","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Heart, Lung, and Blood Institute","keywords":"Genetic enhancement; Cystic fibrosis; Gene delivery; Biology; SWEAT; Gene; Pathology; Genetics; Medicine","score_opus":0.04356070781982467,"score_gpt":0.3381908426845073,"score_spread":0.2946301348646826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967809163","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8236375,0.034151994,0.11379867,0.0061524054,0.0015441279,0.0004900099,0.0011441933,0.00055207737,0.018528953],"genre_scores_gemma":[0.9430256,0.012453285,0.03213507,0.00043238615,0.0001167431,0.00014817264,0.0004597278,0.000098394106,0.011130699],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999783,0.000058774644,0.0000109920275,0.000048782662,0.000066625296,0.00003186104],"domain_scores_gemma":[0.9998765,0.000047779853,0.00001963136,0.00002167738,0.000008308969,0.00002596621],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045935385,0.0003497397,0.0004623999,0.0004751991,0.0004279267,0.0006909434,0.000478601,0.0012416927,0.0008600701],"category_scores_gemma":[0.00023399766,0.00019415317,0.00064845296,0.00024096247,0.0008780178,0.0006738067,0.00036928427,0.0012940143,0.00032920105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015023479,0.000047959933,0.00006406857,0.000089188754,0.000009683475,0.00016261937,0.000068505906,0.00020750103,0.99331725,0.0031317156,0.00028402466,0.0024671725],"study_design_scores_gemma":[0.00010191464,0.00078006973,0.0005712334,0.00003435867,0.00004790607,0.001137684,0.00007439634,0.0026378538,0.9723865,0.0012819541,0.02092591,0.000020264715],"about_ca_topic_score_codex":0.0009944338,"about_ca_topic_score_gemma":0.000920204,"teacher_disagreement_score":0.0012416927,"about_ca_system_score_codex":0.00054556,"about_ca_system_score_gemma":0.00037564966,"threshold_uncertainty_score":0.0039583445},"labels":[],"label_agreement":null},{"id":"W1968509366","doi":"10.1038/sj.gt.3302016","title":"Immunopathology and the gene therapy of lupus","year":2003,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; National Institute on Aging; Juvenile Diabetes Research Foundation International","keywords":"Systemic lupus erythematosus; Immunology; Autoimmunity; Immunopathology; Autoimmune disease; Connective tissue disease; Autoantibody; Lupus erythematosus; Biology; Disease; Population; Immune system; Medicine; Pathology; Antibody","score_opus":0.07350444683651537,"score_gpt":0.36563049471975506,"score_spread":0.2921260478832397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968509366","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005245863,0.998626,0.000105799896,0.00019070953,0.00030541982,0.000003287782,0.0000053375943,0.0000038426883,0.0007071407],"genre_scores_gemma":[0.00033812458,0.9983742,0.00014924383,0.00023111988,0.00026667063,0.000005454361,0.000011459516,9.745168e-7,0.00062264124],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997613,0.000053329844,0.000026586498,0.00003354972,0.00010230326,0.000022985405],"domain_scores_gemma":[0.99954957,0.00025508908,0.00005108267,0.000015509866,0.00009375222,0.000034900262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009069036,0.0012434851,0.002218828,0.002733056,0.00043808087,0.0013550519,0.0012612862,0.0018429663,0.0033116892],"category_scores_gemma":[0.00088745065,0.0003242695,0.00048323788,0.003024608,0.0010643547,0.0016616249,0.000766223,0.0023305214,0.0022046734],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017055104,0.0001309958,0.00020677358,0.015143122,0.00008673534,0.00049433217,0.00007598408,0.000631056,0.0033924724,0.006361077,0.05867432,0.9146326],"study_design_scores_gemma":[0.000041558043,0.000070170434,0.00037346565,0.0021059667,0.00007719831,0.0012671066,0.000047443937,0.00006666433,0.0003947976,0.0020788119,0.9934635,0.000013367586],"about_ca_topic_score_codex":0.00173409,"about_ca_topic_score_gemma":0.003607502,"teacher_disagreement_score":0.0033116892,"about_ca_system_score_codex":0.0009770292,"about_ca_system_score_gemma":0.0013134961,"threshold_uncertainty_score":0.011078715},"labels":[],"label_agreement":null},{"id":"W1970007383","doi":"10.1038/sj.gt.3301934","title":"Postnatal bone marrow stromal cells elicit a potent VEGF-dependent neoangiogenic response in vivo","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":205,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University; Université de Montréal; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Matrigel; Angiogenesis; Ex vivo; Mesenchymal stem cell; Bone marrow; In vivo; Arteriogenesis; Biology; Stromal cell; Neovascularization; Immunology; Vascular endothelial growth factor; CD31; Molecular biology; Cell biology; Cancer research; VEGF receptors","score_opus":0.025080906075251992,"score_gpt":0.2864723838259594,"score_spread":0.2613914777507074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970007383","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833937,0.0021085357,0.008476796,0.0001773344,0.00007758226,0.00012080061,0.0006749573,0.00017118349,0.0047990396],"genre_scores_gemma":[0.9857429,0.0012891653,0.00571962,0.000111502384,0.00005316299,0.000089863206,0.0009824472,0.00008009998,0.005931303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974054,0.000048732978,0.000022941173,0.00003134706,0.000084372325,0.00007215529],"domain_scores_gemma":[0.99954396,0.00017439153,0.00008150651,0.00004808242,0.00004473392,0.00010738675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003983122,0.0005597152,0.00034940493,0.00054817245,0.00015170836,0.00037516773,0.00021490965,0.00036809137,0.0021721572],"category_scores_gemma":[0.00020547363,0.00022442684,0.0003212772,0.00023906562,0.00023485441,0.00023352407,0.0002783325,0.00095234683,0.00073062594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000115758034,0.00004590716,0.0001047056,0.00002144206,0.000003433351,0.000049256734,0.00001627149,0.000037370195,0.9983499,0.00014784216,0.000048634338,0.0010594575],"study_design_scores_gemma":[0.00002236232,0.00021659437,0.001823164,0.000004805214,0.0000125061515,0.00018848255,0.000024559171,0.0003370773,0.99570495,0.000059350252,0.0016043774,0.0000019152612],"about_ca_topic_score_codex":0.00045384886,"about_ca_topic_score_gemma":0.0009839432,"teacher_disagreement_score":0.0021721572,"about_ca_system_score_codex":0.00021563914,"about_ca_system_score_gemma":0.00024558246,"threshold_uncertainty_score":0.0072665215},"labels":[],"label_agreement":null},{"id":"W1971208013","doi":"10.1038/sj.gt.3301886","title":"Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":118,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Immunization; Genetic enhancement; Gene delivery; Virology; Medicine; Adenoviridae; Immunology; Biology; Antibody; Gene","score_opus":0.09270139581148576,"score_gpt":0.40095404006369023,"score_spread":0.30825264425220444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971208013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6691625,0.012638601,0.3101367,0.0006176332,0.000374306,0.00025674474,0.00035015488,0.001211997,0.0052513867],"genre_scores_gemma":[0.8862059,0.0046116356,0.104420066,0.00019118599,0.00010098187,0.00019905336,0.00015119875,0.00013411803,0.003985842],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998653,0.000014531387,0.000011317336,0.00004048884,0.000041192903,0.00002715253],"domain_scores_gemma":[0.9998895,0.000027835544,0.00004185542,0.000014681906,0.000011843664,0.000014292548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016928819,0.00040962975,0.0003145252,0.0002677344,0.00026808077,0.00040120404,0.0003306438,0.00045059124,0.000582166],"category_scores_gemma":[0.0001613666,0.0002548268,0.00035454333,0.00013833412,0.0002871923,0.000518913,0.00034578782,0.00055892434,0.00035829982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019407762,0.00000836185,0.000040604467,0.000042426323,0.0000024629885,0.000038029877,0.0000136634035,0.000029504876,0.9950294,0.00021161395,0.000052382024,0.0045120744],"study_design_scores_gemma":[0.00000455896,0.000083961146,0.00033676822,0.0000033218867,0.000010773337,0.00022854586,0.000006278005,0.00051522197,0.9963515,0.000043511303,0.0024080495,0.000007547464],"about_ca_topic_score_codex":0.00030347845,"about_ca_topic_score_gemma":0.00049838476,"teacher_disagreement_score":0.000582166,"about_ca_system_score_codex":0.0002897832,"about_ca_system_score_gemma":0.00023840439,"threshold_uncertainty_score":0.0021025538},"labels":[],"label_agreement":null},{"id":"W1971386958","doi":"10.1038/gt.2009.80","title":"Intrathecal transplantation of human neural stem cells overexpressing VEGF provide behavioral improvement, disease onset delay and survival extension in transgenic ALS mice","year":2009,"lang":"nl","type":"article","venue":"Gene Therapy","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"Korea Science and Engineering Foundation; Ajou University","keywords":"Neuroprotection; Transplantation; Spinal cord; Neurotrophic factors; Neural stem cell; Vascular endothelial growth factor; Downregulation and upregulation; Medicine; Transgene; Biology; Pathology; Neuroscience; Immunology; Stem cell; Cancer research; Internal medicine; Cell biology; VEGF receptors","score_opus":0.05383197718477919,"score_gpt":0.33542919767039936,"score_spread":0.2815972204856202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971386958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948428,0.0008072767,0.0018775851,0.00025540424,0.00011700398,0.000046739304,0.00047157553,0.00021881708,0.001362811],"genre_scores_gemma":[0.98527145,0.001017147,0.0026552735,0.00009962884,0.00006708914,0.000096406424,0.00072367495,0.0000984841,0.009970902],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997447,0.000029257608,0.000030654573,0.000060951115,0.000055462016,0.00007896895],"domain_scores_gemma":[0.99955255,0.000072507006,0.0001380876,0.00004213925,0.000034556982,0.00016008882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037104837,0.00078565243,0.00054996414,0.000782221,0.00030385307,0.00046479664,0.00050633826,0.00069877156,0.0017646285],"category_scores_gemma":[0.00025220765,0.00029426362,0.00042633136,0.0002753975,0.00066160917,0.0006516448,0.00023551725,0.0016061983,0.00044011767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006000816,0.00024900408,0.00011085587,0.000030337224,0.000010673088,0.00007757394,0.000038431303,0.00010090145,0.99702543,0.00015254463,0.00009136051,0.0015127751],"study_design_scores_gemma":[0.00017463384,0.0016242394,0.0020587463,0.000014959084,0.00007168654,0.00029615161,0.000075220116,0.0013126223,0.9927457,0.00014126279,0.00147332,0.000011352835],"about_ca_topic_score_codex":0.0014007231,"about_ca_topic_score_gemma":0.0022621008,"teacher_disagreement_score":0.0017646285,"about_ca_system_score_codex":0.00038878407,"about_ca_system_score_gemma":0.00058276614,"threshold_uncertainty_score":0.005903244},"labels":[],"label_agreement":null},{"id":"W1971409321","doi":"10.1038/sj.gt.3302683","title":"XIAP-mediated neuroprotection in retinal ischemia","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Florida","keywords":"XIAP; Retina; Neuroprotection; Retinal; Ischemia; TUNEL assay; Genetic enhancement; Biology; Inhibitor of apoptosis; Ophthalmology; Medicine; Apoptosis; Programmed cell death; Neuroscience; Internal medicine; Caspase","score_opus":0.007941548247841518,"score_gpt":0.22385110809719208,"score_spread":0.21590955984935056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971409321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95246047,0.030500356,0.008335271,0.0008785934,0.00021614962,0.000062477215,0.00029733873,0.00032722534,0.0069221067],"genre_scores_gemma":[0.985735,0.007972602,0.0020826831,0.000099435136,0.000046576628,0.00004854597,0.00014053848,0.000018117811,0.003856473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990034,0.000023574912,0.000009597864,0.000013079438,0.00001945473,0.000033944925],"domain_scores_gemma":[0.9999491,0.000011047813,0.000014056069,0.000010631774,0.0000056503063,0.000009608745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030632195,0.0004930468,0.0003739282,0.0005218832,0.0002997849,0.0003898277,0.00035999206,0.0004070924,0.0013540062],"category_scores_gemma":[0.00015959387,0.00017178222,0.000208577,0.00035621444,0.00047783108,0.0005985127,0.00020420781,0.00094355457,0.00022538003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013297073,0.00009998789,0.00016649453,0.00025823602,0.0000335757,0.00033459582,0.000045269884,0.00045536875,0.9747842,0.0027761348,0.00043572948,0.019280694],"study_design_scores_gemma":[0.00008903598,0.0006388884,0.0013107908,0.000014857596,0.00005264839,0.00042231992,0.00002470295,0.00076422724,0.99319446,0.00067084393,0.0028093846,0.000007785162],"about_ca_topic_score_codex":0.0006171877,"about_ca_topic_score_gemma":0.0006872113,"teacher_disagreement_score":0.0013540062,"about_ca_system_score_codex":0.0006038009,"about_ca_system_score_gemma":0.00039367896,"threshold_uncertainty_score":0.0045295954},"labels":[],"label_agreement":null},{"id":"W1974176827","doi":"10.1038/sj.gt.3303039","title":"Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free media","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; National Research Council Canada; Hôtel-Dieu de Québec; Biotechnology Research Institute; Centre hospitalier universitaire de Québec","funders":"","keywords":"Genetic enhancement; Biology; Virology; Retrovirus; Cell culture; Viral vector; Murine leukemia virus; Titer; Transfection; Virus; Recombinant DNA; Gene; Genetics","score_opus":0.03472224418436316,"score_gpt":0.2945979485290745,"score_spread":0.25987570434471136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974176827","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.313999,0.0028851314,0.64566475,0.0006705157,0.0010239073,0.0035073091,0.015957007,0.00482106,0.011471314],"genre_scores_gemma":[0.4023182,0.004073597,0.5107597,0.00041286455,0.00039143057,0.002500853,0.04979836,0.0015140735,0.028230837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933606,0.0001022147,0.00012793834,0.0001045092,0.00026083796,0.00006834912],"domain_scores_gemma":[0.9993587,0.00018593075,0.00006762939,0.0001522255,0.00013440684,0.000101116755],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014735416,0.0011700094,0.0013746205,0.0013870939,0.0006951702,0.0012470305,0.0013846119,0.0011330697,0.0034872848],"category_scores_gemma":[0.0008111336,0.0008874967,0.00069204485,0.0011848017,0.00036201655,0.0007658234,0.0006203886,0.002749368,0.0048005264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051615778,0.00010098268,0.00012481213,0.00005871194,0.0000119492315,0.0000635524,0.000054200023,0.00009975177,0.99464816,0.0008582869,0.00048686794,0.003441062],"study_design_scores_gemma":[0.0000562014,0.00021146525,0.0008565879,0.000016305485,0.00004566027,0.0002905826,0.0000152420735,0.0029902174,0.9835888,0.00030512887,0.011599314,0.00002456958],"about_ca_topic_score_codex":0.0007322092,"about_ca_topic_score_gemma":0.00085299445,"teacher_disagreement_score":0.0034872848,"about_ca_system_score_codex":0.0004791764,"about_ca_system_score_gemma":0.0005272517,"threshold_uncertainty_score":0.011666119},"labels":[],"label_agreement":null},{"id":"W1975100977","doi":"10.1038/gt.2011.11","title":"In vitro and in vivo comparison of viral and cellular internal ribosome entry sites for bicistronic vector expression","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Terry Fox Foundation","keywords":"Internal ribosome entry site; Biology; Translation (biology); Reporter gene; Transfection; Molecular biology; Ribosome; Gene; Cell biology; Virology; Plasmid; Gene expression; Messenger RNA; RNA; Genetics","score_opus":0.04894365000743112,"score_gpt":0.330901576482045,"score_spread":0.2819579264746139,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975100977","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96237034,0.0025849093,0.030754466,0.00012015008,0.00011910076,0.000101030346,0.0007594172,0.00018886907,0.0030017449],"genre_scores_gemma":[0.9734385,0.001094368,0.01725196,0.00007114353,0.000032021,0.00012994108,0.003213183,0.00027601473,0.0044928924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870396,0.00046461204,0.00013722359,0.00020194832,0.00024891717,0.00024321547],"domain_scores_gemma":[0.9986413,0.0007745678,0.0001588178,0.00012761174,0.0001867473,0.0001109315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019071113,0.000751601,0.0007098243,0.0005992482,0.0004125353,0.0010844108,0.00050100876,0.00064840104,0.001757812],"category_scores_gemma":[0.0011354279,0.0005713993,0.0005564136,0.00051573175,0.00054831774,0.00073642714,0.00034240197,0.0013351656,0.0007560635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000203741,0.000031223128,0.000054028787,0.000032989643,0.0000043014034,0.000008160582,0.00002062322,0.00006701304,0.99891067,0.00018477836,0.000020583548,0.00046186376],"study_design_scores_gemma":[0.0000077838085,0.0001311769,0.0003090253,0.0000031062289,0.000015425601,0.000030892672,0.000011092318,0.0005169653,0.99857163,0.000019659832,0.0003799668,0.0000032792673],"about_ca_topic_score_codex":0.0013819799,"about_ca_topic_score_gemma":0.0020022544,"teacher_disagreement_score":0.0019071113,"about_ca_system_score_codex":0.00080955727,"about_ca_system_score_gemma":0.0006402721,"threshold_uncertainty_score":0.010085881},"labels":[],"label_agreement":null},{"id":"W1976815754","doi":"10.1038/sj.gt.3301386","title":"Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Medical Research Council Canada","keywords":"Angiogenesis; Cancer research; Chemokine; Immune system; Biology; Immunology; CXC chemokine receptors; In vivo; Genetic enhancement; Immunotherapy; Chemokine receptor; Gene","score_opus":0.02293792283682564,"score_gpt":0.2637415342067214,"score_spread":0.24080361136989578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976815754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.984861,0.002817452,0.0035462144,0.00043782653,0.00035459572,0.00020146802,0.0002420509,0.0004245724,0.0071148723],"genre_scores_gemma":[0.99245936,0.00077889283,0.0018827092,0.000102181024,0.00013011372,0.00012421496,0.00014665861,0.00004778512,0.0043280516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929476,0.00015109216,0.000037439182,0.00008139531,0.00015432702,0.00028094064],"domain_scores_gemma":[0.99961984,0.00012719039,0.000055475666,0.000052685595,0.000021132733,0.00012367776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044570657,0.0006895011,0.0010211476,0.00096422696,0.00032487628,0.00082513917,0.0003312799,0.00077327294,0.0040896134],"category_scores_gemma":[0.00034250628,0.00027175117,0.00045752065,0.00043367012,0.0006584888,0.00054747664,0.00035144444,0.0027971684,0.0008539203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022555524,0.0014549587,0.00023672276,0.00012743361,0.00002824092,0.000115564144,0.00006306689,0.0007045255,0.979045,0.0010561142,0.00063460524,0.014278231],"study_design_scores_gemma":[0.000660809,0.0058755134,0.0018806932,0.000019346462,0.00011223927,0.00039653608,0.000048153684,0.0024562913,0.9841695,0.00020153075,0.004165594,0.000013871541],"about_ca_topic_score_codex":0.00046950654,"about_ca_topic_score_gemma":0.0009972664,"teacher_disagreement_score":0.0040896134,"about_ca_system_score_codex":0.0004086126,"about_ca_system_score_gemma":0.00062271167,"threshold_uncertainty_score":0.013681173},"labels":[],"label_agreement":null},{"id":"W1978496247","doi":"10.1038/sj.gt.3302355","title":"Polyethyleneimine grafted with pluronic P85 enhances Ku86 antisense delivery and the ionizing radiation treatment efficacy in vivo","year":2004,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Supratek Pharma (Canada); McGill University; Jewish General Hospital; Montreal General Hospital","funders":"National Cancer Institute; Leukemia and Lymphoma Society; National Science Foundation","keywords":"Transfection; In vivo; Cell culture; Molecular biology; Antisense therapy; Biology; Cell; Oligonucleotide; Biochemistry; Gene","score_opus":0.009556445323415475,"score_gpt":0.23192128528365688,"score_spread":0.2223648399602414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978496247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952909,0.0009349717,0.0022785778,0.00003969037,0.000021343278,0.000022652837,0.00006327683,0.00006990047,0.001278727],"genre_scores_gemma":[0.995906,0.0005009993,0.0010952828,0.000016937269,0.000009176914,0.000014119883,0.00010981606,0.000021046513,0.002326627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987626,0.000023803015,0.000009877819,0.000023465916,0.000027328548,0.000039323357],"domain_scores_gemma":[0.99984527,0.00004749456,0.000042227555,0.000019349138,0.00001330377,0.000032276916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026293457,0.00037501132,0.0003189575,0.0002901487,0.00018384749,0.00025224325,0.00018894981,0.00026450856,0.0011288696],"category_scores_gemma":[0.00015684066,0.0001861489,0.00020544368,0.0001779561,0.00026627013,0.0002479706,0.00017232771,0.00050989154,0.00024215571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018991041,0.000024036533,0.00004861495,0.000016343603,0.0000032732094,0.000011201311,0.000010264149,0.00004452938,0.9988708,0.0000845282,0.000010887581,0.00068562553],"study_design_scores_gemma":[0.0000072700864,0.00018089016,0.0005663121,0.0000014779885,0.000008927269,0.000036014204,0.0000039515844,0.00023022149,0.9986286,0.000011744738,0.00032294553,0.0000016881218],"about_ca_topic_score_codex":0.0006162754,"about_ca_topic_score_gemma":0.00046806945,"teacher_disagreement_score":0.0011288696,"about_ca_system_score_codex":0.0001821065,"about_ca_system_score_gemma":0.00026515065,"threshold_uncertainty_score":0.0037764907},"labels":[],"label_agreement":null},{"id":"W1979255161","doi":"10.1038/gt.2011.94","title":"Encapsulated engineered myoblasts can cure Hurler syndrome: preclinical experiments in the mouse model","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Enzyme replacement therapy; Mucopolysaccharidosis I; Mucopolysaccharidosis type I; Mucopolysaccharidosis; Transplantation; Hurler syndrome; Glycosaminoglycan; Lysosomal storage disease; Mucopolysaccharidosis type II; Hunter syndrome; Biology; Stem cell; Pathology; Medicine; Immunology; Cell biology; Disease; Internal medicine; Biochemistry","score_opus":0.11486794796424858,"score_gpt":0.34996029563358894,"score_spread":0.23509234766934034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979255161","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850482,0.003705496,0.006114559,0.00048181188,0.00021120318,0.0002572043,0.00081461575,0.00037984137,0.0029870954],"genre_scores_gemma":[0.9797657,0.0038176458,0.0064601167,0.00015879673,0.00006532686,0.00022680536,0.00096791825,0.00014998383,0.0083876345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948454,0.00012038366,0.000045791854,0.00009953257,0.0001502285,0.000099475445],"domain_scores_gemma":[0.99948335,0.00015995078,0.00014194334,0.00006688318,0.000037133374,0.00011067945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001216473,0.0013739296,0.0008759826,0.0012904481,0.0004326653,0.00059301563,0.00092695217,0.0022127081,0.0016593073],"category_scores_gemma":[0.0005010274,0.00040645024,0.0009053124,0.00035033686,0.0010559341,0.00084013777,0.00040701864,0.0018555993,0.0005063721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010943451,0.0008192507,0.00012972884,0.00012651393,0.00004946836,0.00023017795,0.00008175251,0.00047805454,0.99350065,0.0004333255,0.00019959624,0.002857093],"study_design_scores_gemma":[0.0005006598,0.006335373,0.0009361918,0.000036377518,0.00014721055,0.0002962958,0.000055796703,0.0013073713,0.9883034,0.00020341323,0.0018590054,0.000018776722],"about_ca_topic_score_codex":0.0015193549,"about_ca_topic_score_gemma":0.0021838797,"teacher_disagreement_score":0.0022127081,"about_ca_system_score_codex":0.00043696185,"about_ca_system_score_gemma":0.0004748357,"threshold_uncertainty_score":0.0064333677},"labels":[],"label_agreement":null},{"id":"W1980205385","doi":"10.1038/gt.2014.33","title":"A comparative study of experimental mouse models of central nervous system demyelination","year":2014,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; University of British Columbia; National Eye Institute; University of Alabama","keywords":"Myelin oligodendrocyte glycoprotein; Multiple sclerosis; Central nervous system; Demyelinating disease; Experimental autoimmune encephalomyelitis; Myelin; Immunology; Biology; Proteolipid protein 1; Myelin proteolipid protein; Encephalitis; Myelin basic protein; Virology; Virus; Neuroscience","score_opus":0.11683869212903988,"score_gpt":0.3657047083489396,"score_spread":0.2488660162198997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980205385","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9854402,0.0059405896,0.0037486898,0.00012650863,0.00010366942,0.00020338158,0.0011248022,0.00009464745,0.0032176157],"genre_scores_gemma":[0.9780617,0.0070011048,0.0058336426,0.00017793088,0.00009294863,0.00040861315,0.0025331113,0.00009655914,0.0057944],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914324,0.00024078669,0.00012656143,0.00015085733,0.00014742767,0.00019096906],"domain_scores_gemma":[0.9988778,0.0002605635,0.00026404203,0.00016507105,0.00021862001,0.00021389894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015286359,0.0012867025,0.00077638763,0.0043452317,0.00061973796,0.00063495216,0.00066796667,0.0007630352,0.0022186865],"category_scores_gemma":[0.00065173174,0.000257141,0.0008710183,0.0010230942,0.00074970897,0.0010844629,0.00047324246,0.0009659785,0.0004482032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003891709,0.0014954333,0.001795501,0.00025109205,0.0000665136,0.00028560133,0.00012298308,0.000112765774,0.98780686,0.00059312815,0.00013187075,0.0034464526],"study_design_scores_gemma":[0.00028922156,0.019376203,0.01859012,0.000097647426,0.00051539944,0.0027393498,0.0004604269,0.0006609137,0.9515975,0.00037914413,0.0052583483,0.000035658635],"about_ca_topic_score_codex":0.0012809925,"about_ca_topic_score_gemma":0.00176591,"teacher_disagreement_score":0.0043452317,"about_ca_system_score_codex":0.00049202965,"about_ca_system_score_gemma":0.0003929497,"threshold_uncertainty_score":0.008084297},"labels":[],"label_agreement":null},{"id":"W1981993767","doi":"10.1038/gt.2009.143","title":"DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes","year":2009,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Beta cell; Streptozotocin; Incretin; Transgene; Glucagon-like peptide-1; Insulin; Internal medicine; Endocrinology; Downregulation and upregulation; Biology; Intraperitoneal injection; Glucagon; Diabetes mellitus; In vivo; Medicine; Islet; Type 2 diabetes; Biochemistry; Gene","score_opus":0.02121194816151036,"score_gpt":0.260690325811673,"score_spread":0.23947837765016264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981993767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99483925,0.0007280175,0.0024445455,0.00019475645,0.0001428594,0.00002995564,0.0002728984,0.00021415997,0.0011335142],"genre_scores_gemma":[0.9928058,0.00063795573,0.0024294865,0.00007147883,0.00003281593,0.000036473608,0.00040902063,0.000075254866,0.003501772],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981505,0.000026771886,0.00002431947,0.000038235532,0.000044205222,0.00005139239],"domain_scores_gemma":[0.99980515,0.000034383804,0.000060788654,0.000018921259,0.000013409801,0.00006734308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020925746,0.0006213312,0.00051422697,0.00059552345,0.00023166896,0.0005278559,0.00038993955,0.00047104748,0.0014407865],"category_scores_gemma":[0.00014053706,0.00024273338,0.0003102808,0.00031895022,0.0004666961,0.00034302258,0.0001940806,0.0014560893,0.0003993768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021786602,0.00006598328,0.00005982158,0.000022268561,0.000005057866,0.000041899184,0.000013669699,0.00007198154,0.9984029,0.000110219866,0.000034871962,0.000953572],"study_design_scores_gemma":[0.000059309372,0.00043493148,0.00075406075,0.0000045088377,0.000020331794,0.00013392048,0.000032478154,0.0010204051,0.99625635,0.00005877889,0.0012201131,0.0000048571683],"about_ca_topic_score_codex":0.00063076115,"about_ca_topic_score_gemma":0.00060898566,"teacher_disagreement_score":0.0014407865,"about_ca_system_score_codex":0.00037336117,"about_ca_system_score_gemma":0.00032801557,"threshold_uncertainty_score":0.0048199296},"labels":[],"label_agreement":null},{"id":"W1982307191","doi":"10.1038/gt.2011.181","title":"dsAAV8-mediated gene transfer and β-cell expression of IL-4 and β-cell growth factors are capable of reversing early-onset diabetes in NOD mice","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Deutsche Forschungsgemeinschaft; Michael Smith Health Research BC; Stem Cell Network","keywords":"NOD mice; Nod; Genetic enhancement; Biology; Immunology; Diabetes mellitus; In vivo; Cell growth; Adoptive cell transfer; T cell; Cancer research; Endocrinology; Immune system; Gene","score_opus":0.019236685466002604,"score_gpt":0.22703600151668554,"score_spread":0.20779931605068294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982307191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98999363,0.0011729312,0.0057142377,0.00018060036,0.00011013515,0.00006271525,0.0005591258,0.00026962344,0.0019369808],"genre_scores_gemma":[0.9790317,0.0010937203,0.007481442,0.00010299061,0.000056725254,0.00016031472,0.0011635305,0.00019629662,0.010713381],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995653,0.00007500332,0.000060022627,0.00009038055,0.00009661876,0.000112567766],"domain_scores_gemma":[0.999542,0.00008372075,0.00015991442,0.0000614112,0.000028857334,0.00012413759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037167888,0.0009046286,0.00047569696,0.0009823514,0.00028199187,0.0005401429,0.0006472681,0.0008406875,0.0017023247],"category_scores_gemma":[0.00028675728,0.00047230528,0.00058771187,0.0002793542,0.00061669346,0.00053708843,0.00028501262,0.0018783448,0.00063255907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018867331,0.00004360331,0.000070586764,0.000018928904,0.0000041888547,0.00004331506,0.000012009474,0.000044445762,0.99885845,0.00020839804,0.000015947306,0.0004914066],"study_design_scores_gemma":[0.000039544397,0.00016620527,0.00046146606,0.0000046734085,0.000013396624,0.00015250457,0.000010435779,0.00035670729,0.9978859,0.00006457055,0.00084138295,0.0000032079247],"about_ca_topic_score_codex":0.00054536446,"about_ca_topic_score_gemma":0.0005794612,"teacher_disagreement_score":0.0017023247,"about_ca_system_score_codex":0.0003843721,"about_ca_system_score_gemma":0.0003094672,"threshold_uncertainty_score":0.005694866},"labels":[],"label_agreement":null},{"id":"W1982688102","doi":"10.1038/sj.gt.3302802","title":"Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF121 (AdVEGF121) versus maximum medical treatment","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":283,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Manitoba Health; Hôpital du Sacré-Cœur de Montréal; Vancouver Hospital and Health Sciences Centre; St. Michael's Hospital; Sunnybrook Health Science Centre; Victoria Heart Institute Foundation; University of Alberta Hospital; Montreal Heart Institute; Alberta Hospital Edmonton; Foothills Medical Centre; Royal Victoria Hospital; Women's College Hospital; Hôpital Notre-Dame; London Health Sciences Centre","funders":"","keywords":"Angina; Medicine; Revascularization; Genetic enhancement; Canadian Cardiovascular Society; Clinical endpoint; Coronary artery disease; Cardiology; Randomized controlled trial; Internal medicine; Therapeutic angiogenesis; Perfusion; Adverse effect; Surgery; Angiogenesis; Neovascularization; Myocardial infarction; Gene; Biology","score_opus":0.008016024261516347,"score_gpt":0.2603112171652076,"score_spread":0.2522951929036913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982688102","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98997366,0.0036649988,0.00093215215,0.000846443,0.00056313945,0.0018753638,0.00061453524,0.00012571832,0.0014040517],"genre_scores_gemma":[0.9879802,0.0022539352,0.0018101484,0.0009368054,0.00077400147,0.003066483,0.0007432799,0.00003703865,0.002398176],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9991479,0.00045145908,0.000037668888,0.00013616128,0.000054192322,0.00017264168],"domain_scores_gemma":[0.9991326,0.00032862078,0.00015312542,0.00006644083,0.000034749362,0.00028442443],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019726304,0.002386402,0.0048262416,0.00066264404,0.00050025,0.0013770924,0.0011646742,0.0022594032,0.00536986],"category_scores_gemma":[0.0017657282,0.00086293457,0.0017042307,0.0007136379,0.0019200615,0.0015046485,0.00045012354,0.0039302837,0.0006923935],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9823132,0.0057775327,0.00024087739,0.00021556782,0.00035768977,0.000020739131,0.000025897623,0.0002615657,0.0021468902,0.000086039225,0.00032377048,0.008230177],"study_design_scores_gemma":[0.9581463,0.040312752,0.0004866728,0.000007987517,0.00019566041,0.000011652554,0.0000091278525,0.00024771917,0.00030737466,0.000076099146,0.00019054845,0.000008099224],"about_ca_topic_score_codex":0.0010308807,"about_ca_topic_score_gemma":0.0017225656,"teacher_disagreement_score":0.00536986,"about_ca_system_score_codex":0.00088589016,"about_ca_system_score_gemma":0.0010834462,"threshold_uncertainty_score":0.017964005},"labels":[],"label_agreement":null},{"id":"W1983239966","doi":"10.1038/sj.gt.3302005","title":"Herpes simplex virus type-1 infection upregulates cellular promoters and telomerase activity in both tumor and nontumor human cells","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; McMaster University; University of British Columbia","funders":"University of Pittsburgh; University of Pennsylvania","keywords":"Telomerase reverse transcriptase; Biology; Telomerase; Promoter; Herpes simplex virus; Virology; Viral vector; Gene expression; Viral replication; Carcinogenesis; Molecular biology; Gene; Virus; Genetics; Recombinant DNA","score_opus":0.01683701982396412,"score_gpt":0.28097962333377874,"score_spread":0.2641426035098146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983239966","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899596,0.004696192,0.0027778067,0.000056637055,0.00005288259,0.000031181364,0.0004020468,0.00014426342,0.0018793494],"genre_scores_gemma":[0.9921828,0.0016814088,0.001084327,0.000015233789,0.000025140575,0.000029938456,0.00072334526,0.00003976309,0.0042179804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999793,0.000038676902,0.000017265013,0.000032846296,0.000048573555,0.00006960448],"domain_scores_gemma":[0.999706,0.00013218688,0.000035128298,0.000050671268,0.000031000232,0.000045047553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002791718,0.00039239269,0.00032231325,0.0006272287,0.00024632184,0.0007576452,0.00020243746,0.00021065919,0.0018715789],"category_scores_gemma":[0.00033350824,0.00021662997,0.0002921645,0.00040947416,0.00028463002,0.0003858261,0.000321749,0.0004962332,0.00040972815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002224911,0.000038680013,0.00034508982,0.000028074179,0.0000064769874,0.000038770457,0.000046457022,0.00005573152,0.997401,0.00035705423,0.000047451074,0.0014129016],"study_design_scores_gemma":[0.000010036111,0.00018551649,0.0017400308,0.0000031449285,0.000015776344,0.00011185178,0.00003317055,0.0003149608,0.9960372,0.00007760059,0.0014679397,0.0000026650932],"about_ca_topic_score_codex":0.0010545207,"about_ca_topic_score_gemma":0.0010603999,"teacher_disagreement_score":0.0018715789,"about_ca_system_score_codex":0.00034475033,"about_ca_system_score_gemma":0.0003455578,"threshold_uncertainty_score":0.0062610507},"labels":[],"label_agreement":null},{"id":"W1983598547","doi":"10.1038/gt.2010.71","title":"BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease","year":2010,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":101,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Instituto de Salud Carlos III; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada; Fundació la Marató de TV3","keywords":"Quinolinate; Neurotrophic factors; Neuroprotection; Brain-derived neurotrophic factor; Glial fibrillary acidic protein; Astrocyte; Huntingtin; Biology; Genetically modified mouse; Gliosis; Transgene; Glial cell line-derived neurotrophic factor; Huntington's disease; Microglia; Internal medicine; Endocrinology; Pharmacology; Quinolinic acid; Immunology; Neuroscience; Medicine; Central nervous system; Inflammation; Biochemistry; Disease; Receptor","score_opus":0.040675871294183735,"score_gpt":0.2753190214075541,"score_spread":0.23464315011337036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983598547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98552567,0.0012923745,0.0116176335,0.00013746807,0.00006595224,0.000021816004,0.00013257723,0.00013136136,0.0010751644],"genre_scores_gemma":[0.9894394,0.0010041493,0.006750994,0.00003929012,0.000017670356,0.000026292244,0.00012981397,0.000048611906,0.0025437817],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991655,0.000013906229,0.000010479676,0.000016117345,0.000024960484,0.000017970546],"domain_scores_gemma":[0.9999418,0.00001023945,0.00001690797,0.0000073610045,0.00000981377,0.000013890541],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013518019,0.00022992723,0.00021026225,0.00011860224,0.00014077256,0.00023889358,0.00019614915,0.0002647056,0.00036578331],"category_scores_gemma":[0.00007742196,0.000120156416,0.00019884517,0.000072662566,0.00019298376,0.00018950968,0.0001664814,0.00041038392,0.0001340299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070336624,0.000012505606,0.000039148643,0.000012768345,0.0000018726101,0.000037813286,0.000010062039,0.000026377518,0.99896574,0.00012650456,0.000014638225,0.00068220636],"study_design_scores_gemma":[0.000011236417,0.000116151714,0.000521648,0.000002319646,0.000017813989,0.0001832777,0.00001116519,0.0004215361,0.99753726,0.000052185693,0.0011226542,0.0000028246693],"about_ca_topic_score_codex":0.0005351951,"about_ca_topic_score_gemma":0.0009959385,"teacher_disagreement_score":0.0005351951,"about_ca_system_score_codex":0.00012953482,"about_ca_system_score_gemma":0.00017746791,"threshold_uncertainty_score":0.0012236834},"labels":[],"label_agreement":null},{"id":"W1986347124","doi":"10.1038/sj.gt.3301532","title":"Transfection of large plasmids in primary human myoblasts","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Medical Research Council Canada; Muscular Dystrophy Association","keywords":"Transfection; Molecular biology; Biology; Plasmid; Duchenne muscular dystrophy; Genetic enhancement; Gene delivery; Myocyte; Polyethylenimine; Dystrophin; Cell culture; Cell biology; DNA; Gene; Biochemistry; Genetics","score_opus":0.016753118416582446,"score_gpt":0.3043335316002507,"score_spread":0.2875804131836682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986347124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.74465555,0.010075879,0.20840274,0.0010360582,0.0013151001,0.0024366335,0.010991365,0.0021979185,0.018888703],"genre_scores_gemma":[0.7891386,0.0057006036,0.12499245,0.00047997118,0.00021947247,0.0016947868,0.024771575,0.0005611319,0.052441325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931014,0.00013622497,0.000081141574,0.00013749898,0.00016857382,0.00016641566],"domain_scores_gemma":[0.99952614,0.00023216858,0.00002703572,0.00009649509,0.00004935923,0.000068881345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013821386,0.0007181602,0.0010817142,0.0007104851,0.0006899981,0.0008233692,0.00058960513,0.0008292276,0.003703651],"category_scores_gemma":[0.0006020026,0.00051905616,0.0008590074,0.00086745963,0.00048069615,0.00051452976,0.0007364032,0.0018392289,0.0021120189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018179396,0.00008942236,0.0001400716,0.00014987844,0.000022335687,0.00008658388,0.00014485228,0.00014433407,0.99332196,0.0010628515,0.0004522222,0.0042036492],"study_design_scores_gemma":[0.00007732805,0.00037409918,0.0017337429,0.000025780771,0.000068596724,0.00021312978,0.000044004886,0.0010799882,0.98374397,0.00022382634,0.012406499,0.000009080568],"about_ca_topic_score_codex":0.0020692693,"about_ca_topic_score_gemma":0.0032679106,"teacher_disagreement_score":0.003703651,"about_ca_system_score_codex":0.0007047286,"about_ca_system_score_gemma":0.00074007065,"threshold_uncertainty_score":0.012389958},"labels":[],"label_agreement":null},{"id":"W1987421759","doi":"10.1038/gt.2010.125","title":"Readministration of helper-dependent adenoviral vectors to mouse airway mediated via transient immunosuppression","year":2010,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Cystic Fibrosis Canada; Foundation Fighting Blindness; Cystic Fibrosis Foundation","keywords":"Immune system; Viral vector; Genetic enhancement; Transgene; Biology; Immunology; Immunogenicity; Gene delivery; Adenoviridae; Cyclophosphamide; Vector (molecular biology); Virology; Gene; Recombinant DNA; Chemotherapy","score_opus":0.013886611905742374,"score_gpt":0.28852655677538097,"score_spread":0.2746399448696386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987421759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9714642,0.0032956367,0.01778463,0.00025119737,0.00057529216,0.00048649003,0.00060487865,0.0009426871,0.004594858],"genre_scores_gemma":[0.98188525,0.0014147797,0.0075898664,0.00010382291,0.00017711913,0.00026901456,0.00073426653,0.00012196355,0.0077039427],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938345,0.000070517395,0.000056396428,0.0001302984,0.0001239686,0.00023528248],"domain_scores_gemma":[0.99959654,0.00012874398,0.00007457599,0.00009334027,0.000034701836,0.0000721727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006032084,0.0008198137,0.0006562049,0.00067643565,0.00034991882,0.0005804426,0.000588824,0.0007372979,0.0020509553],"category_scores_gemma":[0.00030655973,0.00029182376,0.0006946026,0.00036759867,0.0005958771,0.00042481822,0.0003191327,0.0017481353,0.00062510476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030445188,0.00008186058,0.00009456438,0.000038004422,0.0000048245233,0.000081169404,0.000028794415,0.000053026888,0.9973028,0.0003646529,0.000051282175,0.0015944412],"study_design_scores_gemma":[0.0000187574,0.00025699835,0.00025502025,0.0000018778369,0.000010555889,0.000058969137,0.000005524725,0.0001907556,0.9983368,0.000022478012,0.00084043405,0.0000017882647],"about_ca_topic_score_codex":0.0006323014,"about_ca_topic_score_gemma":0.0008796343,"teacher_disagreement_score":0.0020509553,"about_ca_system_score_codex":0.00039536803,"about_ca_system_score_gemma":0.000540182,"threshold_uncertainty_score":0.0068611503},"labels":[],"label_agreement":null},{"id":"W1987427709","doi":"10.1038/gt.2008.40","title":"Taming the Trojan horse: optimizing dynamic carrier cell/oncolytic virus systems for cancer biotherapy","year":2008,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Regional Cancer Foundation; University of Ottawa","funders":"","keywords":"Oncolytic virus; Trojan horse; Biology; Virus; In vivo; Ex vivo; Virology; Computer science; Biotechnology","score_opus":0.04591931529685724,"score_gpt":0.36857581281323304,"score_spread":0.3226564975163758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987427709","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0020180168,0.985727,0.0077986,0.00037826574,0.00046317856,0.000028881292,0.000032167645,0.00007448877,0.003479285],"genre_scores_gemma":[0.008955184,0.97800034,0.0073728836,0.00035122273,0.00014357545,0.000050007027,0.00009753,0.000026696447,0.0050024637],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99983966,0.000019542582,0.000009912013,0.0000321178,0.00007612386,0.000022645743],"domain_scores_gemma":[0.9999031,0.000040785373,0.0000141569235,0.0000060512302,0.000027259988,0.000008628036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057432865,0.0011502529,0.0011733163,0.00081861275,0.0003209408,0.001063789,0.0012691414,0.0013671694,0.0014930399],"category_scores_gemma":[0.00032741256,0.00039298172,0.00034692354,0.0012024472,0.0007961069,0.0016678245,0.00060250255,0.0018267748,0.0016632923],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011002079,0.0001535907,0.00012234207,0.005445442,0.000051777402,0.00028498247,0.00012986186,0.0021448112,0.08935046,0.016387055,0.015420383,0.8703993],"study_design_scores_gemma":[0.00003877494,0.00018545247,0.00023252057,0.00041864358,0.00006145044,0.0009422693,0.00005546833,0.00096148683,0.048102584,0.0032943473,0.9456706,0.000036346915],"about_ca_topic_score_codex":0.0010249907,"about_ca_topic_score_gemma":0.0015607108,"teacher_disagreement_score":0.0014930399,"about_ca_system_score_codex":0.0009051774,"about_ca_system_score_gemma":0.00065967685,"threshold_uncertainty_score":0.006567478},"labels":[],"label_agreement":null},{"id":"W1990803471","doi":"10.1038/gt.2011.59","title":"Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada","funders":"National Institute of Allergy and Infectious Diseases; INOVIO Pharmaceuticals; Los Alamos National Laboratory; University of Pennsylvania","keywords":"Immunogenicity; Adjuvant; DNA vaccination; Biology; Immune system; Virology; Vaccination; Immunization; Antigen; Hemagglutinin (influenza); Immunity; Immunology; HMGB1; Influenza A virus; Antibody; Virus; Inflammation","score_opus":0.09631824046157805,"score_gpt":0.36288036323450346,"score_spread":0.2665621227729254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990803471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99523574,0.0015381103,0.0017147261,0.00014160847,0.00007026532,0.000060425657,0.00007605061,0.0000335215,0.0011296296],"genre_scores_gemma":[0.9963393,0.0006267813,0.0011452722,0.000067893576,0.000034799887,0.000034646466,0.00009309247,0.000007862002,0.0016503293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998379,0.00006309296,0.000008913044,0.000016896156,0.000021206639,0.00005190108],"domain_scores_gemma":[0.99990046,0.0000351073,0.000017833318,0.000010948142,0.000012193644,0.000023469327],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039075955,0.00026402806,0.00024061235,0.00024259686,0.00010165368,0.00023367973,0.00017552469,0.00030030214,0.0018910681],"category_scores_gemma":[0.00022642055,0.000105454805,0.00018849417,0.00009989239,0.00023726808,0.00022291357,0.00019193099,0.00057082635,0.00037983202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016010633,0.000241501,0.0002317585,0.000063456486,0.000010246778,0.000022519464,0.000024652465,0.00014812103,0.9930447,0.00021090606,0.000058523226,0.004342512],"study_design_scores_gemma":[0.00016330821,0.004011477,0.0012566627,0.000011152941,0.00003745904,0.000069327594,0.00002874578,0.0005357835,0.9924142,0.000081467544,0.0013875349,0.0000028617617],"about_ca_topic_score_codex":0.00022555006,"about_ca_topic_score_gemma":0.00030535678,"teacher_disagreement_score":0.0018910681,"about_ca_system_score_codex":0.00014828234,"about_ca_system_score_gemma":0.0002006019,"threshold_uncertainty_score":0.006326258},"labels":[],"label_agreement":null},{"id":"W1992998779","doi":"10.1038/sj.gt.3301052","title":"Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":346,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Supratek Pharma (Canada); Institut National de la Recherche Scientifique","funders":"National Science Foundation","keywords":"Transfection; Gene delivery; Cationic polymerization; Copolymer; Polyelectrolyte; Ethylene glycol; Polymer chemistry; Chemistry; In vitro; Biophysics; Polymer; Materials science; Biochemistry; Biology; Organic chemistry; Gene","score_opus":0.03366078611093105,"score_gpt":0.3022364834910384,"score_spread":0.26857569738010734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992998779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98801684,0.0052456507,0.0042871977,0.00005727578,0.000038340284,0.0001021358,0.00007403672,0.000042236097,0.0021363192],"genre_scores_gemma":[0.98990506,0.0036598307,0.0039463253,0.000023831579,0.00001726615,0.00005866676,0.000086202155,0.000020494303,0.0022823727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997286,0.00009459806,0.000014783026,0.000034500168,0.00007423515,0.00005323217],"domain_scores_gemma":[0.9997881,0.00008763991,0.000043677,0.000010926781,0.00003746431,0.000032334654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005512825,0.0004197245,0.00024277596,0.0003271951,0.00020066962,0.00033174353,0.00017956375,0.00033188114,0.00065751764],"category_scores_gemma":[0.00051628775,0.00014732707,0.00017807152,0.00024263411,0.00022248359,0.00035770715,0.00013502572,0.00025889918,0.00018126593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043252323,0.00012808068,0.00011957335,0.000087430686,0.000006471704,0.000070514034,0.000027900081,0.00059967634,0.9939354,0.00023578363,0.00002394276,0.0043327296],"study_design_scores_gemma":[0.000022904987,0.0009962936,0.00027259698,0.0000036100867,0.000012585321,0.000043351607,0.0000069697094,0.0005758981,0.997235,0.00001961304,0.0008080275,0.000003077502],"about_ca_topic_score_codex":0.00052145857,"about_ca_topic_score_gemma":0.0006416909,"teacher_disagreement_score":0.00065751764,"about_ca_system_score_codex":0.0002998155,"about_ca_system_score_gemma":0.00034345058,"threshold_uncertainty_score":0.0029155016},"labels":[],"label_agreement":null},{"id":"W1993612411","doi":"10.1038/gt.2011.91","title":"Efficient cochlear gene transfection in guinea-pigs with adeno-associated viral vectors by partial digestion of round window membrane","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Eye Institute","keywords":"Round window; Transfection; Cochlea; Biology; Genetic enhancement; Adeno-associated virus; Collagenase; Viral vector; Gene delivery; Inner ear; Cell biology; Vector (molecular biology); Molecular biology; Gene; Recombinant DNA; Anatomy; Genetics; Biochemistry; Enzyme","score_opus":0.035379039746216326,"score_gpt":0.2426613134535286,"score_spread":0.20728227370731228,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993612411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8727159,0.0035365943,0.11349535,0.00041669596,0.0003888874,0.000816369,0.001158827,0.0011176175,0.0063537336],"genre_scores_gemma":[0.9198861,0.0038355186,0.05918409,0.00010759993,0.0000664179,0.0006879841,0.0014658493,0.00021535128,0.014551003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996401,0.000049924896,0.000036767047,0.000095447635,0.00006877675,0.000108954424],"domain_scores_gemma":[0.99967074,0.000112748756,0.00008009721,0.00006946315,0.0000272018,0.00003977871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00077905535,0.000840764,0.0004597258,0.0006409947,0.00031015626,0.00047339854,0.0006151224,0.00083637435,0.002019992],"category_scores_gemma":[0.00038712722,0.00055337854,0.0006780322,0.00020883471,0.00067887135,0.00058857934,0.0004714543,0.0010573283,0.0011222471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059594986,0.000012974201,0.00002532695,0.000028340015,0.000003695017,0.00004172436,0.000026306767,0.000032065673,0.99847776,0.00037388568,0.000020617328,0.00089765515],"study_design_scores_gemma":[0.00002041182,0.00021167174,0.00038134228,0.00001137148,0.000019710295,0.00017364068,0.000015494501,0.00037874203,0.99676776,0.00008203042,0.001932606,0.0000051981065],"about_ca_topic_score_codex":0.0006653874,"about_ca_topic_score_gemma":0.0009399314,"teacher_disagreement_score":0.002019992,"about_ca_system_score_codex":0.00024285352,"about_ca_system_score_gemma":0.0004656705,"threshold_uncertainty_score":0.0067575574},"labels":[],"label_agreement":null},{"id":"W1993700109","doi":"10.1038/gt.2015.13","title":"Lister strain vaccinia virus with thymidine kinase gene deletion is a tractable platform for development of a new generation of oncolytic virus","year":2015,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Barts Cancer Institute; Medical Research Council; Science and Technology Department of Henan Province; Deutsche Forschungsgemeinschaft; Royal College of Surgeons of England; Cancer Research UK","keywords":"Oncolytic virus; Vaccinia; Biology; Thymidine kinase; Virus; Virology; In vivo; Gene; Genetics; Recombinant DNA; Herpes simplex virus","score_opus":0.10055313741834189,"score_gpt":0.33420273834714537,"score_spread":0.2336496009288035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993700109","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8721727,0.002999512,0.1164288,0.0003143683,0.00016686528,0.00016302784,0.0014490071,0.0012831991,0.005022382],"genre_scores_gemma":[0.9339524,0.0016497393,0.055360813,0.00006308923,0.000036262107,0.00011190658,0.0024034719,0.00022135307,0.0062010065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998368,0.00002758746,0.000013160232,0.000035021803,0.00005420539,0.000033258366],"domain_scores_gemma":[0.99985063,0.000029514567,0.000059905353,0.000022091712,0.000008531804,0.000029232257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026380538,0.0004974033,0.00036619327,0.00049775286,0.00020357386,0.0004240923,0.00040862057,0.0003504902,0.00067942997],"category_scores_gemma":[0.00015195302,0.00030312393,0.00033349555,0.00020269086,0.0003756432,0.00037996407,0.00040890893,0.0010893594,0.00068084884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075781885,0.000022261464,0.000143681,0.000023529345,0.000004041726,0.000051099196,0.000014700309,0.00006987463,0.99700683,0.0010927771,0.00006355838,0.0014319217],"study_design_scores_gemma":[0.000019433159,0.0001695004,0.0005562408,0.0000064420838,0.000013986038,0.00031028924,0.000010737506,0.00065272924,0.99162406,0.00019611882,0.00643175,0.000008806141],"about_ca_topic_score_codex":0.00029615074,"about_ca_topic_score_gemma":0.0004102718,"teacher_disagreement_score":0.00067942997,"about_ca_system_score_codex":0.00037403035,"about_ca_system_score_gemma":0.00036782178,"threshold_uncertainty_score":0.0027137995},"labels":[],"label_agreement":null},{"id":"W1993976861","doi":"10.1038/gt.2014.77","title":"Overexpression of X-Linked Inhibitor of Apoptotic Protein (XIAP) reduces age-related neuronal degeneration in the mouse cochlea","year":2014,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Efferent; XIAP; Cochlea; Neurite; Spiral ganglion; Biology; Inhibitor of apoptosis; Hair cell; Hearing loss; Neuroscience; Endocrinology; Apoptosis; Programmed cell death; Medicine; Afferent; Audiology; Caspase","score_opus":0.03903336665012436,"score_gpt":0.2718988094488429,"score_spread":0.23286544279871857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993976861","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929133,0.0021349224,0.0031413909,0.00018917857,0.000060200597,0.000022513865,0.0002156728,0.00016361286,0.0011591094],"genre_scores_gemma":[0.99210936,0.00158331,0.0018191125,0.000054645134,0.000015921836,0.000027657754,0.00022425217,0.00004188661,0.004123885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99976116,0.00003088043,0.000030180392,0.000050989023,0.000059592483,0.000067279456],"domain_scores_gemma":[0.9996798,0.000058142097,0.00010571568,0.0000348281,0.000023041208,0.00009851491],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027994392,0.00046986967,0.00043390814,0.00072738394,0.00022883002,0.00047466104,0.00039867742,0.0006746642,0.0015180123],"category_scores_gemma":[0.00022305558,0.00023631463,0.0003179726,0.00031584947,0.0005231757,0.0005585489,0.00024611526,0.00093525386,0.00031703178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022206006,0.00005045741,0.00008469469,0.000024771489,0.000007807677,0.000055102064,0.000011815095,0.00008258022,0.998555,0.0001157806,0.000027182921,0.00076281774],"study_design_scores_gemma":[0.000037911996,0.00045662958,0.0017199928,0.0000065152017,0.000039330043,0.00017044225,0.00004126091,0.00077172107,0.9958597,0.00008866324,0.00080242316,0.0000055419655],"about_ca_topic_score_codex":0.00064961653,"about_ca_topic_score_gemma":0.0008534331,"teacher_disagreement_score":0.0015180123,"about_ca_system_score_codex":0.00034088938,"about_ca_system_score_gemma":0.00033914897,"threshold_uncertainty_score":0.005078256},"labels":[],"label_agreement":null},{"id":"W1994558354","doi":"10.1038/gt.2015.22","title":"Cochlear protection against cisplatin by viral transfection of X-linked inhibitor of apoptosis protein across round window membrane","year":2015,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"XIAP; Round window; Cochlea; Inhibitor of apoptosis; Inner ear; Cisplatin; Apoptosis; Transfection; Ototoxicity; Biology; Hearing loss; Cell biology; Transgene; Cancer research; Programmed cell death; Medicine; Anatomy; Gene; Caspase; Chemotherapy; Biochemistry","score_opus":0.06253737917088607,"score_gpt":0.290239711026957,"score_spread":0.22770233185607092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994558354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99102366,0.001762911,0.0046757953,0.0001941907,0.00011640663,0.00007260772,0.00014171435,0.0001309253,0.00188181],"genre_scores_gemma":[0.9946694,0.0010092442,0.0015831646,0.000042515294,0.000013274997,0.000045981873,0.00016374691,0.000015723806,0.0024570064],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998272,0.000026544067,0.000014792875,0.000038333917,0.00003718145,0.000055933033],"domain_scores_gemma":[0.9998764,0.000034860037,0.000028860435,0.000021046471,0.000015266447,0.000023591396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022381356,0.0004132003,0.00034282103,0.00027571514,0.00023792118,0.00033153675,0.00034126788,0.00046161396,0.0017668507],"category_scores_gemma":[0.00019306142,0.00019891343,0.0003623957,0.00018154581,0.0003834833,0.0005475422,0.00024465536,0.000944131,0.00033823875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034615633,0.000060860995,0.000060935105,0.000032433698,0.000008041796,0.000050308372,0.000027536285,0.00006489162,0.997883,0.00036536768,0.00005017713,0.0010501347],"study_design_scores_gemma":[0.00005550037,0.0006646261,0.00074151286,0.000005201433,0.000024684057,0.00013450414,0.000032496344,0.0007708084,0.9965082,0.000077131685,0.000980302,0.0000050263516],"about_ca_topic_score_codex":0.00076544983,"about_ca_topic_score_gemma":0.0006217589,"teacher_disagreement_score":0.0017668507,"about_ca_system_score_codex":0.00031451322,"about_ca_system_score_gemma":0.00050961366,"threshold_uncertainty_score":0.005910754},"labels":[],"label_agreement":null},{"id":"W1995610685","doi":"10.1038/gt.2011.159","title":"Effect of topical interferon-γ gene therapy using gemini nanoparticles on pathophysiological markers of cutaneous scleroderma in Tsk/+ mice","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo; University Health Network; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cytokine; Immunology; Genetic enhancement; Gene delivery; Cancer research; Gene","score_opus":0.05388471441130025,"score_gpt":0.28143092264383623,"score_spread":0.227546208232536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995610685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99644655,0.0008089822,0.0012393019,0.00020486505,0.000091548216,0.00003754194,0.00018499563,0.00012251556,0.0008636598],"genre_scores_gemma":[0.99552876,0.0005180557,0.0012927059,0.000068718626,0.000028539484,0.00004833641,0.00015646874,0.000033683933,0.002324882],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997571,0.00004675321,0.000025489582,0.000063967535,0.000040754458,0.000065948945],"domain_scores_gemma":[0.9997367,0.00005430924,0.000076645294,0.00003465438,0.00001901531,0.000078580306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027248435,0.0005795388,0.00058548775,0.00036347937,0.00020553281,0.00031607688,0.00020933946,0.0007353342,0.0011314744],"category_scores_gemma":[0.00015073217,0.00023773113,0.0004133447,0.00017030169,0.00053497095,0.00040113635,0.00012874242,0.0011847719,0.00024595245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008267071,0.00011569367,0.000052162788,0.000024350315,0.000005627465,0.00003551255,0.000015037791,0.000048558275,0.9981736,0.00004206362,0.000024548412,0.00063612044],"study_design_scores_gemma":[0.00007594287,0.0010305862,0.00085313,0.000003685274,0.000032386288,0.00008982749,0.000023377836,0.0005313246,0.99693954,0.00003363555,0.00038121964,0.0000053557555],"about_ca_topic_score_codex":0.0006876198,"about_ca_topic_score_gemma":0.000675127,"teacher_disagreement_score":0.0011314744,"about_ca_system_score_codex":0.00023007022,"about_ca_system_score_gemma":0.0002356983,"threshold_uncertainty_score":0.0037851334},"labels":[],"label_agreement":null},{"id":"W1996515420","doi":"10.1038/gt.2008.58","title":"Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma","year":2008,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"National Cancer Institute","keywords":"Oncolytic virus; Melanoma; Biology; Cancer research; Interferon; In vivo; Bystander effect; Cell culture; Programmed cell death; Virology; Virotherapy; Immunology; Virus; Apoptosis","score_opus":0.026649212289378697,"score_gpt":0.2851690401873192,"score_spread":0.2585198278979405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996515420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9162094,0.06273897,0.013616879,0.0006379878,0.0003228651,0.00009819465,0.00016797097,0.00016118679,0.006046563],"genre_scores_gemma":[0.98024005,0.012885336,0.0024893002,0.000050866107,0.00003806158,0.000028786997,0.00008746549,0.000023321538,0.004156814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991727,0.000012619749,0.0000040652267,0.000011218629,0.000022472177,0.000032296546],"domain_scores_gemma":[0.99997306,0.000006343609,0.000005766169,0.0000042407364,0.000004302009,0.000006358509],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019250062,0.00028259068,0.00024351849,0.00025601228,0.00014536576,0.00035003742,0.00020673763,0.00030130727,0.00072886335],"category_scores_gemma":[0.0000956142,0.00009592553,0.0002768486,0.00012348815,0.00024669038,0.00022967,0.00011824923,0.000643754,0.00018423391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042442614,0.00007959649,0.00008752158,0.00012872384,0.000009638511,0.00009432308,0.000043172102,0.00046708077,0.9812485,0.0010533307,0.00018542087,0.016178435],"study_design_scores_gemma":[0.00009891157,0.0009072547,0.00063949544,0.000019711899,0.000039253344,0.00042340337,0.00002492193,0.0010297656,0.9866654,0.00021384997,0.009929217,0.000008760142],"about_ca_topic_score_codex":0.0011757722,"about_ca_topic_score_gemma":0.0013953029,"teacher_disagreement_score":0.0011757722,"about_ca_system_score_codex":0.00038917788,"about_ca_system_score_gemma":0.00031657482,"threshold_uncertainty_score":0.0028236508},"labels":[],"label_agreement":null},{"id":"W1997136944","doi":"10.1038/sj.gt.3302075","title":"Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Alkaline phosphatase; Recombinant DNA; Viral vector; Bone morphogenetic protein 2; Bone morphogenetic protein; Bone morphogenetic protein 7; In vivo; In vitro; Human bone; Genetic enhancement; Molecular biology; Bone morphogenetic protein 6; Adenoviridae; Biology; Chemistry; Biochemistry; Enzyme; Biotechnology; Gene","score_opus":0.009944467905602968,"score_gpt":0.23621997275525816,"score_spread":0.2262755048496552,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997136944","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99461466,0.0018326195,0.0022921993,0.00006814184,0.00003821489,0.000022092543,0.00014461635,0.000036705016,0.0009507419],"genre_scores_gemma":[0.9923779,0.0014750456,0.0031293896,0.000028392644,0.000011184145,0.000025758378,0.00032457052,0.000025130366,0.0026026422],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996474,0.00005235332,0.00005151517,0.000051469648,0.000099162855,0.00009812158],"domain_scores_gemma":[0.9996426,0.00011479837,0.00008209498,0.00003204964,0.000045679317,0.00008281219],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062993297,0.0004019383,0.00033328545,0.00083706045,0.00022624014,0.00053039123,0.00029788545,0.0004173291,0.00074911653],"category_scores_gemma":[0.00038273007,0.00021450962,0.00033547165,0.0003852061,0.000525201,0.0004386272,0.0002238443,0.0005125407,0.0001542976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005929543,0.00009615785,0.00033730574,0.000059982907,0.000012624068,0.00004069433,0.000048439128,0.0002408916,0.99371225,0.0008698815,0.00002902604,0.003959752],"study_design_scores_gemma":[0.00003373576,0.0007560788,0.00087371946,0.000011087422,0.00008058947,0.0000991188,0.00004458832,0.00083418615,0.99610066,0.00014021625,0.0010164861,0.00000945473],"about_ca_topic_score_codex":0.0012957742,"about_ca_topic_score_gemma":0.0011571958,"teacher_disagreement_score":0.0012957742,"about_ca_system_score_codex":0.00044192644,"about_ca_system_score_gemma":0.0005838547,"threshold_uncertainty_score":0.0033314228},"labels":[],"label_agreement":null},{"id":"W1997546231","doi":"10.1038/sj.gt.3302968","title":"Nacystelyn enhances adenoviral vector-mediated gene delivery to mouse airways","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Foundation Fighting Blindness; Cystic Fibrosis Foundation","keywords":"Genetic enhancement; Gene delivery; Viral vector; Adenoviridae; Cystic fibrosis; Vector (molecular biology); Nebulizer; Mucociliary clearance; Immunology; Biology; Medicine; Pharmacology; Virology; Gene; Recombinant DNA; Lung; Internal medicine","score_opus":0.013623576950031777,"score_gpt":0.2531554162758518,"score_spread":0.23953183932582003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997546231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97715044,0.00481484,0.010312435,0.00037463248,0.00018451254,0.00022268307,0.00083561084,0.000529715,0.0055751633],"genre_scores_gemma":[0.98115635,0.0016632136,0.0076493453,0.00006682836,0.000052088737,0.0000976215,0.0005895746,0.00010181065,0.008623287],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992995,0.00013117028,0.00007416706,0.00012869172,0.00021505635,0.00015131406],"domain_scores_gemma":[0.99951637,0.00013168297,0.00012140173,0.000056881127,0.000048721355,0.00012494012],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060139096,0.00054461544,0.00061813137,0.0006926252,0.00034076543,0.0006548202,0.0005892029,0.00064184656,0.001880064],"category_scores_gemma":[0.0003169949,0.00033236528,0.00044178954,0.00028649057,0.0006683694,0.0006851285,0.00035641686,0.0012423339,0.0005836747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015326051,0.000024738763,0.000051452393,0.00002908247,0.0000029902078,0.000030345103,0.000013492178,0.00004620285,0.9989349,0.00015903352,0.00002084423,0.00053371844],"study_design_scores_gemma":[0.0000109179255,0.00013051821,0.00039887504,0.0000027267727,0.000008190885,0.000067993176,0.000007216652,0.00032243395,0.9982064,0.000017423763,0.0008251754,0.000002085205],"about_ca_topic_score_codex":0.0015523022,"about_ca_topic_score_gemma":0.0031195842,"teacher_disagreement_score":0.001880064,"about_ca_system_score_codex":0.0007815057,"about_ca_system_score_gemma":0.00064123364,"threshold_uncertainty_score":0.0062894225},"labels":[],"label_agreement":null},{"id":"W1997818839","doi":"10.1038/gt.2011.5","title":"Potent, tumor-specific gene expression in an orthotopic hepatoma rat model using a Survivin-targeted, amplifiable adenoviral vector","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Survivin; Cancer research; Biology; Genetic enhancement; Bioluminescence imaging; Reporter gene; Luciferase; Viral vector; Hepatocellular carcinoma; Tumor necrosis factor alpha; Transgene; Adenoviridae; Transduction (biophysics); Systemic administration; Apoptosis; Gene expression; In vivo; Gene; Immunology; Transfection; Recombinant DNA","score_opus":0.07020716680548615,"score_gpt":0.29921369655008306,"score_spread":0.2290065297445969,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997818839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9680724,0.001636961,0.024464717,0.0002929951,0.00017729931,0.00021241514,0.000733628,0.0006353118,0.003774395],"genre_scores_gemma":[0.97928953,0.0014808588,0.009371141,0.000037900783,0.000026594658,0.00010339461,0.000563246,0.000079925434,0.009047365],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974245,0.000029863146,0.000027178961,0.00005623373,0.00007093866,0.00007337899],"domain_scores_gemma":[0.9997662,0.000033646233,0.0000665794,0.0000434849,0.000027865044,0.000062214014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005298369,0.0010506376,0.00044666053,0.000949759,0.00029973063,0.00049136323,0.00035402537,0.00032540484,0.0011054418],"category_scores_gemma":[0.00014410794,0.00037699568,0.0004604788,0.00042974684,0.00056921464,0.00056376564,0.0002672478,0.0010849604,0.00043142357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025692428,0.00010631522,0.00009728458,0.000035172365,0.0000073528963,0.00007101863,0.000041987998,0.0001367147,0.9975942,0.0004361001,0.000073291594,0.0011437465],"study_design_scores_gemma":[0.000031278807,0.00056081126,0.00047234754,0.000003848781,0.000029509727,0.00012682642,0.000022484894,0.00071680266,0.9969495,0.000044778724,0.0010371255,0.000004826164],"about_ca_topic_score_codex":0.002569813,"about_ca_topic_score_gemma":0.003589666,"teacher_disagreement_score":0.002569813,"about_ca_system_score_codex":0.0004556878,"about_ca_system_score_gemma":0.0006717469,"threshold_uncertainty_score":0.005109668},"labels":[],"label_agreement":null},{"id":"W1998798768","doi":"10.1038/gt.2013.24","title":"MicroRNA-regulated non-viral vectors with improved tumor specificity in an orthotopic rat model of hepatocellular carcinoma","year":2013,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Hepatocellular carcinoma; microRNA; Biology; Virology; Vector (molecular biology); Viral vector; Cancer research; Gene; Genetics; Recombinant DNA","score_opus":0.013008112973202684,"score_gpt":0.212686047960424,"score_spread":0.19967793498722133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998798768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98697484,0.0013415412,0.009345148,0.0002392677,0.00015463732,0.0001066946,0.0002676961,0.00028741165,0.0012827974],"genre_scores_gemma":[0.9846128,0.0012834908,0.008698309,0.000051645613,0.00003767061,0.00013481463,0.0004130863,0.00011265238,0.004655578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994419,0.000113056696,0.000052427036,0.00008215368,0.00016033878,0.00015002082],"domain_scores_gemma":[0.9997328,0.000048226302,0.00007922342,0.0000401052,0.000031882115,0.000067651294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006830468,0.00081071054,0.00080594275,0.00083913526,0.0002930212,0.0004264308,0.0005307566,0.00045365814,0.00097534293],"category_scores_gemma":[0.00026189903,0.00040057534,0.0005074769,0.00047308236,0.0006383169,0.00061978254,0.0002316217,0.0010460987,0.000399627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041905552,0.00016319133,0.00004655581,0.000047837217,0.000006981571,0.000065838874,0.000026877224,0.00013794689,0.99713516,0.00039946934,0.000061425846,0.0014896702],"study_design_scores_gemma":[0.00003439692,0.0006972993,0.00026569833,0.0000020794503,0.0000214454,0.00009907375,0.000011364783,0.00058879034,0.99767345,0.00003021691,0.0005700975,0.000006207305],"about_ca_topic_score_codex":0.001247192,"about_ca_topic_score_gemma":0.001709753,"teacher_disagreement_score":0.001247192,"about_ca_system_score_codex":0.0005310931,"about_ca_system_score_gemma":0.00066807494,"threshold_uncertainty_score":0.0038533807},"labels":[],"label_agreement":null},{"id":"W2000073114","doi":"10.1038/sj.gt.3301689","title":"Human urinary bladder carcinomas express adenovirus attachment and internalization receptors","year":2002,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Akademiska Sjukhuset; McMaster University","keywords":"Internalization; Biology; Receptor; Urinary bladder; Urinary system; Adenoviridae; Genetic enhancement; Urothelium; Virology; Cancer research; Urology; Medicine; Gene; Anatomy; Genetics","score_opus":0.0367126181174113,"score_gpt":0.3067112050095313,"score_spread":0.26999858689212003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000073114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98037875,0.0077305445,0.007567933,0.00016727309,0.00009191141,0.000052379983,0.0003765294,0.00013754275,0.003497083],"genre_scores_gemma":[0.98517007,0.003258004,0.0033634747,0.000028414075,0.000014223015,0.000025002646,0.0006851261,0.000022878408,0.0074328613],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998048,0.000031253254,0.00001307113,0.00002613285,0.000047904217,0.00007679729],"domain_scores_gemma":[0.9998472,0.00006033044,0.000018388762,0.000033906854,0.00002443673,0.000015831769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038273243,0.00035794408,0.00032377246,0.00041706485,0.00033663397,0.00070356304,0.00022426985,0.00045543438,0.0012072737],"category_scores_gemma":[0.0003482266,0.00031229528,0.0003701824,0.00036710943,0.0002749405,0.00044167583,0.00028579216,0.00038593003,0.00062115624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027933772,0.000037926016,0.0010961788,0.000087864326,0.000014226258,0.00013158863,0.00011729458,0.00015614962,0.9923252,0.0013543272,0.00014810775,0.0042518713],"study_design_scores_gemma":[0.000025655703,0.00024732653,0.006285226,0.000013226415,0.000056397217,0.00060777285,0.000099090044,0.0012318902,0.9803038,0.00019127666,0.010924768,0.000013448519],"about_ca_topic_score_codex":0.0045425612,"about_ca_topic_score_gemma":0.003300996,"teacher_disagreement_score":0.0045425612,"about_ca_system_score_codex":0.0009376255,"about_ca_system_score_gemma":0.0005316642,"threshold_uncertainty_score":0.009032249},"labels":[],"label_agreement":null},{"id":"W2000370758","doi":"10.1038/sj.gt.3302063","title":"Cotransfection of heme oxygenase-1 prevents the acute inflammation elicited by a second adenovirus","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Lawson Health Research Institute","funders":"","keywords":"Heme oxygenase; Adenoviridae; Inflammation; Genetic enhancement; Biology; Immunology; Adenovirus infection; Heme; Viral vector; Gene delivery; Gene; Virology; Enzyme; Virus; Recombinant DNA; Genetics; Biochemistry","score_opus":0.007378333066276335,"score_gpt":0.23106194878651712,"score_spread":0.22368361572024079,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000370758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887416,0.0019284073,0.0058077676,0.00041371564,0.00045957902,0.00010647792,0.00045183406,0.00028955823,0.0018010956],"genre_scores_gemma":[0.9818555,0.0011294858,0.0068458514,0.00011559377,0.00009979461,0.00013952822,0.0009854251,0.00007891069,0.00874983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992842,0.00010216749,0.0000800916,0.00013919538,0.00013464145,0.00025976394],"domain_scores_gemma":[0.9990671,0.0002835408,0.0001669848,0.00015960539,0.00006320596,0.00025954013],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063014973,0.0011901616,0.000919336,0.0009914176,0.00040799275,0.0010445954,0.00061744713,0.0009967706,0.0022213408],"category_scores_gemma":[0.00035262076,0.00047038455,0.00063084444,0.0004573318,0.00092075835,0.00074241206,0.000331618,0.0035452414,0.0007422362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055876793,0.0002685262,0.000096414864,0.00004367971,0.00001002151,0.000050575884,0.000030106781,0.000059907896,0.99741685,0.0004937175,0.00009231285,0.00087924436],"study_design_scores_gemma":[0.00009223204,0.0005629202,0.00077813485,0.000007726552,0.000027387914,0.00011440999,0.00003169642,0.00085282355,0.99606496,0.00005112483,0.0014103465,0.000006140133],"about_ca_topic_score_codex":0.001738031,"about_ca_topic_score_gemma":0.0019749533,"teacher_disagreement_score":0.0022213408,"about_ca_system_score_codex":0.0011266748,"about_ca_system_score_gemma":0.0010344392,"threshold_uncertainty_score":0.008174658},"labels":[],"label_agreement":null},{"id":"W2000541283","doi":"10.1038/gt.2010.137","title":"Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device","year":2010,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada","funders":"Public Health Agency of Canada","keywords":"Electroporation; Immunogenicity; ELISPOT; DNA vaccination; Biology; Antigen; Adjuvant; Virology; Genetic enhancement; Vector (molecular biology); Plasmid; Transfection; Immune system; Immunology; Recombinant DNA; DNA; Cell culture; Gene; T cell; Immunization; Genetics","score_opus":0.027232268688235944,"score_gpt":0.2991434984964274,"score_spread":0.2719112298081915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000541283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.554585,0.0013910056,0.43539277,0.00091321603,0.0005206636,0.0015180389,0.00039461977,0.0016477858,0.003636942],"genre_scores_gemma":[0.85714847,0.0007710709,0.13449588,0.00031032859,0.000062156105,0.0007170394,0.0003588755,0.00011843128,0.0060176672],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99968994,0.00004886421,0.000023166062,0.000056392102,0.0001402959,0.00004141451],"domain_scores_gemma":[0.99952745,0.00014849601,0.00009940403,0.00005762751,0.00010423734,0.000062809384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00097032584,0.00037866062,0.00029286396,0.0002468666,0.00016704063,0.00041919848,0.00088513334,0.00069995894,0.001418258],"category_scores_gemma":[0.0007547649,0.00021086757,0.00032691416,0.00010820195,0.0003352424,0.0006662012,0.0003240788,0.0005036226,0.00043539456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031946995,0.00024606314,0.00034674,0.00015681933,0.00001466525,0.00013719033,0.00008541215,0.00038055328,0.9853098,0.00055777316,0.00052074034,0.011924749],"study_design_scores_gemma":[0.00017276227,0.0067536966,0.0022801675,0.000026124824,0.00006993099,0.0012855798,0.00005093083,0.0047887615,0.97316056,0.00021735183,0.011163001,0.000031054755],"about_ca_topic_score_codex":0.000096305615,"about_ca_topic_score_gemma":0.00008600738,"teacher_disagreement_score":0.001418258,"about_ca_system_score_codex":0.00019037121,"about_ca_system_score_gemma":0.0003551871,"threshold_uncertainty_score":0.0051316023},"labels":[],"label_agreement":null},{"id":"W2003955696","doi":"10.1038/sj.gt.3302036","title":"Molecular basis of the inflammatory response to adenovirus vectors","year":2003,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":427,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Libin Cardiovascular Institute of Alberta","funders":"","keywords":"Biology; Adenoviridae; Innate immune system; Viral vector; Chemokine; Genetic enhancement; Transduction (biophysics); Acquired immune system; Vectors in gene therapy; Cell biology; Gene delivery; Proinflammatory cytokine; Immune system; Virology; Inflammation; Immunology; Gene; Genetics","score_opus":0.032712299341192796,"score_gpt":0.3356475460909968,"score_spread":0.302935246749804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003955696","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041388843,0.99483407,0.0016207463,0.00044128273,0.00042744528,0.000011220812,0.00002776849,0.00001890754,0.002204694],"genre_scores_gemma":[0.002367152,0.99481165,0.00084509834,0.00019818293,0.00021557303,0.000018834962,0.000044313085,0.000002971593,0.0014962594],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99983597,0.000024819994,0.000020501773,0.00003146291,0.000065831744,0.000021462101],"domain_scores_gemma":[0.9998248,0.000080037935,0.000017123033,0.000009364787,0.000054900094,0.000013712032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061400037,0.0010231419,0.0012777798,0.0015902929,0.00030886618,0.0013029837,0.00113821,0.0013912718,0.0014205776],"category_scores_gemma":[0.00036841803,0.00041593844,0.0003537231,0.0012316569,0.0011483944,0.0010841516,0.0004258722,0.0027285214,0.0015636679],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004114077,0.00028816774,0.00039331446,0.013194836,0.00008871127,0.0015096678,0.00015888279,0.0022461165,0.07763842,0.041451048,0.028238432,0.8343809],"study_design_scores_gemma":[0.00005615916,0.00013374478,0.0007387176,0.0011036511,0.00007143701,0.0024287796,0.00007992215,0.00034226806,0.023720857,0.011233804,0.96005255,0.00003809963],"about_ca_topic_score_codex":0.0012659366,"about_ca_topic_score_gemma":0.0012526583,"teacher_disagreement_score":0.0015902929,"about_ca_system_score_codex":0.0015079877,"about_ca_system_score_gemma":0.0011607319,"threshold_uncertainty_score":0.010941207},"labels":[],"label_agreement":null},{"id":"W2005199266","doi":"10.1038/gt.2011.26","title":"A bidirectional promoter architecture enhances lentiviral transgenesis in embryonic and extraembryonic stem cells","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; RNA interference; Transgene; Transgenesis; Promoter; Gene silencing; Cell biology; Viral vector; Genetics; Chromatin; RNA; Gene; Gene expression; Reproductive technology","score_opus":0.028733941045386107,"score_gpt":0.2636224944813807,"score_spread":0.2348885534359946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005199266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93190986,0.0014973432,0.060791735,0.00017329954,0.00010806939,0.00013317988,0.0004155611,0.0007559801,0.0042149085],"genre_scores_gemma":[0.959928,0.0010613153,0.03313855,0.00006994121,0.00003560072,0.00013069954,0.00060467253,0.0003127271,0.0047185156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997149,0.000040990744,0.000031697913,0.00005802139,0.000096160235,0.000058203892],"domain_scores_gemma":[0.9996972,0.000053760356,0.0000891727,0.000049710623,0.000042080046,0.00006810927],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003523153,0.0005821846,0.0003093949,0.00041832848,0.0002534573,0.00059842435,0.0003792894,0.00042165347,0.0010016895],"category_scores_gemma":[0.00023879246,0.0004412689,0.0004180936,0.00029103467,0.00035301314,0.00033745528,0.0003586258,0.0010646787,0.00073788373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050393493,0.000020875146,0.0000624615,0.00001780049,0.000002483932,0.00001366805,0.000006865358,0.000083903375,0.99821305,0.00037872352,0.000015766751,0.0011340262],"study_design_scores_gemma":[0.000020839405,0.000110037116,0.0004883242,0.000006089255,0.000022429562,0.00011621193,0.000007690342,0.0008752721,0.99648607,0.000084189705,0.0017779798,0.000004876517],"about_ca_topic_score_codex":0.00060340395,"about_ca_topic_score_gemma":0.0011978243,"teacher_disagreement_score":0.0010016895,"about_ca_system_score_codex":0.0004290573,"about_ca_system_score_gemma":0.00074486784,"threshold_uncertainty_score":0.0033509731},"labels":[],"label_agreement":null},{"id":"W2005291427","doi":"10.1038/gt.2009.82","title":"Isolation and evaluation of novel adeno-associated virus sequences from porcine tissues","year":2009,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Food Inspection Agency; University of Manitoba; Public Health Agency of Canada","funders":"","keywords":"Biology; Adeno-associated virus; Genetic enhancement; Virology; Capsid; Transduction (biophysics); Recombinant DNA; Molecular biology; Gene delivery; Virus; Antiserum; Antigen; Vector (molecular biology); Gene; Immunology; Genetics","score_opus":0.05219163286658095,"score_gpt":0.35313227751424664,"score_spread":0.3009406446476657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005291427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96902823,0.0023743648,0.02580573,0.00013887968,0.00009970974,0.00025397702,0.00076911587,0.0000599366,0.0014700759],"genre_scores_gemma":[0.9220393,0.0034530598,0.059114683,0.00018379919,0.00008088633,0.0003005332,0.00929961,0.00009841402,0.0054298667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997116,0.0000682099,0.000030475228,0.00006033198,0.00006840918,0.000060916143],"domain_scores_gemma":[0.99944884,0.000232941,0.00009507618,0.000054525855,0.000080730984,0.00008784812],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005472883,0.0005097448,0.00041707893,0.00042824968,0.0003154778,0.0006333463,0.00039387622,0.00055795687,0.0009060217],"category_scores_gemma":[0.0006940329,0.00026648727,0.0005358334,0.00023496505,0.00043861763,0.0004941685,0.000230045,0.0010103515,0.0005369431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000074611664,0.000026603559,0.00008677742,0.000030234256,0.0000029136997,0.000033026863,0.000014380808,0.00008614441,0.9987556,0.00007267528,0.000009692642,0.0008073556],"study_design_scores_gemma":[0.000033188542,0.0011455098,0.0016816079,0.000013298256,0.000043277098,0.00047457742,0.000052756073,0.00075732346,0.99266183,0.00009550112,0.0030338692,0.000007220021],"about_ca_topic_score_codex":0.00057725236,"about_ca_topic_score_gemma":0.000756599,"teacher_disagreement_score":0.0009060217,"about_ca_system_score_codex":0.00044936148,"about_ca_system_score_gemma":0.0006150963,"threshold_uncertainty_score":0.003260374},"labels":[],"label_agreement":null},{"id":"W2005676026","doi":"10.1038/sj.gt.3302578","title":"DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Nod; NOD mice; Autoimmunity; Biology; Immunology; CD40; DNA vaccination; CD28; Antigen presentation; Antigen; Antibody; Immune system; T cell; Diabetes mellitus; Cytotoxic T cell; Endocrinology; Immunization; In vitro; Genetics","score_opus":0.005225709731919416,"score_gpt":0.2209003222230195,"score_spread":0.2156746124911001,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005676026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99144757,0.0009610349,0.0037813997,0.00030875643,0.00023249883,0.000070351896,0.00040058614,0.00041029032,0.0023875511],"genre_scores_gemma":[0.9859061,0.0010456286,0.0037253487,0.00019509399,0.00011039885,0.00011139,0.000601537,0.00013405416,0.008170498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994772,0.00007491251,0.00004701022,0.00013979584,0.00010786556,0.00015319606],"domain_scores_gemma":[0.9995048,0.00007488565,0.00017499478,0.000052975014,0.000031569114,0.00016070281],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045085142,0.0011291525,0.0008330711,0.0009935673,0.00030189415,0.000532956,0.00065120985,0.0010287082,0.0014797772],"category_scores_gemma":[0.00028508354,0.00042031994,0.00058092416,0.0003190685,0.00062422664,0.0005102849,0.00025285123,0.0020940516,0.0004979285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080967945,0.00039334854,0.00022275437,0.000047207603,0.000016059894,0.00006768597,0.000023134808,0.00014226345,0.99633527,0.00016813853,0.000080645055,0.0016938585],"study_design_scores_gemma":[0.0003196871,0.0024341375,0.0023987764,0.000021588194,0.000090798814,0.00033995486,0.000043163807,0.0015321022,0.9905657,0.00013696984,0.00210281,0.000014312865],"about_ca_topic_score_codex":0.0008674345,"about_ca_topic_score_gemma":0.0010863986,"teacher_disagreement_score":0.0014797772,"about_ca_system_score_codex":0.0005662102,"about_ca_system_score_gemma":0.00046956536,"threshold_uncertainty_score":0.0049503446},"labels":[],"label_agreement":null},{"id":"W2008486721","doi":"10.1038/gt.2009.51","title":"Human neural stem cells overexpressing glial cell line-derived neurotrophic factor in experimental cerebral hemorrhage","year":2009,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"National Science Council","keywords":"Glial cell line-derived neurotrophic factor; Neurotrophic factors; Neural stem cell; Transplantation; Glial fibrillary acidic protein; Biology; Immunostaining; Pathology; Neuroscience; Stem cell; Immunology; Cell biology; Medicine; Internal medicine; Immunohistochemistry; Receptor; Biochemistry","score_opus":0.05195542627598005,"score_gpt":0.2906038973863653,"score_spread":0.23864847111038523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008486721","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915474,0.0030860107,0.0023551614,0.00017486607,0.00023072309,0.00017409318,0.0002116826,0.00010053941,0.0021194804],"genre_scores_gemma":[0.9919734,0.002963614,0.0016981233,0.000064014974,0.00008201276,0.00012937794,0.00037940874,0.000020185666,0.002689767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99971074,0.00006628568,0.00003568986,0.000034150766,0.00007222384,0.00008093733],"domain_scores_gemma":[0.999835,0.00005820172,0.000024228977,0.00002937365,0.00001790809,0.00003530867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007890956,0.0004697709,0.0007449243,0.0011287669,0.00044230343,0.00042889005,0.00044404902,0.0004923264,0.0012879432],"category_scores_gemma":[0.00034043242,0.0002928723,0.00046259147,0.0005522791,0.0010246143,0.00040266523,0.00023186431,0.000866918,0.00030144348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0071664145,0.0014826332,0.00065325416,0.00027578103,0.00007431981,0.0014457516,0.00025281208,0.00047503095,0.9772931,0.001487562,0.000442945,0.008950372],"study_design_scores_gemma":[0.00066192215,0.003580188,0.0017412878,0.000016789254,0.00017836747,0.0006840139,0.00009368564,0.0011001742,0.9885378,0.00025991644,0.0031330613,0.000012830705],"about_ca_topic_score_codex":0.0026671358,"about_ca_topic_score_gemma":0.0022990273,"teacher_disagreement_score":0.0026671358,"about_ca_system_score_codex":0.00045541726,"about_ca_system_score_gemma":0.00068110717,"threshold_uncertainty_score":0.005303204},"labels":[],"label_agreement":null},{"id":"W2009444560","doi":"10.1038/sj.gt.3301740","title":"Genome medicine: gene therapy for the millennium, 30 September–3 October 2001, Rome, Italy","year":2002,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"BC Cancer Agency; Medical Research Council; University of Cambridge","keywords":"Genetic enhancement; Genome; Human genome; Biology; Gene; Computational biology; DNA sequencing; Genetics; Bioinformatics","score_opus":0.041992856484771135,"score_gpt":0.3057602708264479,"score_spread":0.2637674143416768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009444560","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.030131396,0.3860612,0.011258418,0.10891565,0.08474599,0.0010817356,0.002273453,0.0017993106,0.3737328],"genre_scores_gemma":[0.046354868,0.078057475,0.0037896873,0.0073469942,0.015829347,0.00022283944,0.001432315,0.0005693393,0.8463972],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99932027,0.000079327925,0.00003274475,0.0001756831,0.00018823435,0.0002037845],"domain_scores_gemma":[0.9992112,0.0001791549,0.00007364559,0.000030390918,0.0001551054,0.0003505469],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001449903,0.0014650857,0.0013615406,0.0009836991,0.0015983566,0.0019960182,0.0010242503,0.00456124,0.075920545],"category_scores_gemma":[0.0008405533,0.00045739443,0.0006439952,0.00055412325,0.0011346964,0.0011400937,0.0012748975,0.0034442835,0.036044944],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002053828,0.00040839988,0.0014907778,0.00096640375,0.00007184576,0.0019513245,0.00038671336,0.0008815483,0.016212957,0.0035442677,0.746669,0.22536299],"study_design_scores_gemma":[0.00019842146,0.00081163086,0.008585653,0.00034409543,0.000044552213,0.0014109715,0.00018811929,0.0006279889,0.005129352,0.0011417866,0.9814767,0.00004071381],"about_ca_topic_score_codex":0.001088945,"about_ca_topic_score_gemma":0.0062116305,"teacher_disagreement_score":0.075920545,"about_ca_system_score_codex":0.0013952007,"about_ca_system_score_gemma":0.0007340778,"threshold_uncertainty_score":0.25397956},"labels":[],"label_agreement":null},{"id":"W2010328268","doi":"10.1038/gt.2014.83","title":"Clonal variation in interferon response determines the outcome of oncolytic virotherapy in mouse CT26 colon carcinoma model","year":2014,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"Canadian Institutes of Health Research","keywords":"Oncolytic virus; Biology; Interferon; Virotherapy; Virology; Cancer research; Virus; Glioma; Immunology","score_opus":0.03245715144093694,"score_gpt":0.3173466698922736,"score_spread":0.2848895184513367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010328268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987729,0.00018636572,0.00042732176,0.00001843953,0.000005926848,0.000007687949,0.0001169063,0.000018224771,0.00044607706],"genre_scores_gemma":[0.9984493,0.00010377239,0.0002885917,0.000014200455,0.0000036471974,0.000014859626,0.00010986565,0.000009193106,0.0010064553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983895,0.000026500467,0.00001204874,0.000032514352,0.000036517602,0.00005351093],"domain_scores_gemma":[0.99974245,0.00007084327,0.00007426563,0.00003188464,0.00002550623,0.00005507512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015529954,0.0001500294,0.00016211643,0.00028234939,0.00011919134,0.00019858313,0.00011359982,0.0002863565,0.0009402372],"category_scores_gemma":[0.00021198721,0.000109047585,0.00013594297,0.00015695991,0.00019007393,0.00015807647,0.00010029222,0.00061097066,0.00016481978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015621653,0.000034673805,0.0003144773,0.000004719517,0.0000016247557,0.0000141582495,0.0000122123565,0.00008504717,0.9988901,0.000048330072,0.000016655533,0.00042177658],"study_design_scores_gemma":[0.000015591613,0.0006189912,0.0076316525,0.0000025424079,0.0000151817085,0.00011273274,0.000023925397,0.0014103183,0.9897794,0.000048685917,0.0003347486,0.000006203394],"about_ca_topic_score_codex":0.00057539076,"about_ca_topic_score_gemma":0.00074231793,"teacher_disagreement_score":0.0009402372,"about_ca_system_score_codex":0.0002523989,"about_ca_system_score_gemma":0.00012920902,"threshold_uncertainty_score":0.0031453967},"labels":[],"label_agreement":null},{"id":"W2010388612","doi":"10.1038/gt.2008.54","title":"Immunity to adeno-associated virus vectors in animals and humans: a continued challenge","year":2008,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":180,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Heart and Stroke Foundation of Canada","keywords":"Adeno-associated virus; Genetic enhancement; Biology; Immune system; Vector (molecular biology); Transgene; Gene delivery; Immunity; Virology; Virus; Viral vector; Innate immune system; Acquired immune system; Immunology; Capsid; Gene; Recombinant DNA; Genetics","score_opus":0.06828153963896955,"score_gpt":0.3638678367695622,"score_spread":0.29558629713059265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010388612","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011257143,0.99653494,0.0005193467,0.0014911785,0.00064752373,0.0000033367016,0.0000107832975,0.000013153286,0.00066722964],"genre_scores_gemma":[0.00062539993,0.9964586,0.00052541,0.0009264924,0.00059773534,0.000010678205,0.000023656497,0.0000036194265,0.0008284374],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99964035,0.00008231219,0.00004091676,0.00006171833,0.00014030673,0.000034477718],"domain_scores_gemma":[0.99909043,0.00055887474,0.00006228556,0.000029006113,0.00019147924,0.000067924295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016328798,0.0010633209,0.0028258585,0.001104363,0.00044820408,0.0016180035,0.0014609348,0.0031246303,0.003426913],"category_scores_gemma":[0.0013038601,0.00032615737,0.00048673488,0.0011502655,0.0015606864,0.002679517,0.0006749536,0.0045324815,0.0025860253],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001333528,0.00009603457,0.00017578514,0.006704547,0.000045096862,0.00021835502,0.00008953669,0.000274564,0.0054818275,0.012152159,0.062425375,0.9122033],"study_design_scores_gemma":[0.000024437695,0.000114406444,0.00030167963,0.0013416227,0.000046031655,0.00083184766,0.00008411541,0.00006407572,0.0008625665,0.0031460545,0.9931676,0.000015639824],"about_ca_topic_score_codex":0.0009880196,"about_ca_topic_score_gemma":0.0016116297,"teacher_disagreement_score":0.003426913,"about_ca_system_score_codex":0.0012084784,"about_ca_system_score_gemma":0.0018286495,"threshold_uncertainty_score":0.011464179},"labels":[],"label_agreement":null},{"id":"W2011614230","doi":"10.1038/sj.gt.3301793","title":"Adenovirus-based libraries: efficient generation of recombinant adenoviruses by positive selection with the adenovirus protease","year":2002,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Transfection; Recombinant DNA; Virology; Plasmid; Viral vector; Adenoviridae; Vector (molecular biology); Virus; Cell culture; Gene; Molecular biology; Computational biology; Genetics","score_opus":0.028030736921618466,"score_gpt":0.2594051893694837,"score_spread":0.23137445244786523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011614230","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.35320583,0.0064925984,0.6142721,0.0005816784,0.00055215455,0.0019860954,0.007677328,0.004282733,0.01094947],"genre_scores_gemma":[0.6399358,0.010848524,0.28972566,0.00035460232,0.0001718194,0.0014816003,0.0247945,0.0015244386,0.031163009],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991055,0.00018161297,0.00008918947,0.00011422008,0.00038491987,0.00012444849],"domain_scores_gemma":[0.99947184,0.00015417856,0.00009139893,0.000078601144,0.00007793386,0.00012614821],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011553961,0.0011848994,0.0010987206,0.0015226332,0.00051153183,0.0013358142,0.0010378106,0.0005583836,0.002822802],"category_scores_gemma":[0.0008448086,0.00090066844,0.0007167298,0.0010750745,0.000408377,0.0006747491,0.00080932584,0.0017283896,0.0030395137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032060864,0.00011891846,0.00016585707,0.00016429712,0.000028185066,0.00008798184,0.000054018157,0.00023609355,0.98469245,0.0013864784,0.0007577687,0.011987293],"study_design_scores_gemma":[0.00007450315,0.00020780838,0.00032652775,0.00001191648,0.0000478075,0.0004209657,0.00001149359,0.0011019938,0.98476416,0.00022300943,0.012791109,0.000018712459],"about_ca_topic_score_codex":0.00035935515,"about_ca_topic_score_gemma":0.0008394275,"teacher_disagreement_score":0.002822802,"about_ca_system_score_codex":0.000522073,"about_ca_system_score_gemma":0.0006109841,"threshold_uncertainty_score":0.009443283},"labels":[],"label_agreement":null},{"id":"W2018196746","doi":"10.1038/sj.gt.3302932","title":"Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Science Council","keywords":"Medulloblastoma; Cytosine deaminase; Neural stem cell; Cancer research; Glioma; Biology; Systemic administration; Stem cell; Genetic enhancement; In vivo; Gene; Cell biology","score_opus":0.04711239520690628,"score_gpt":0.28822077357638337,"score_spread":0.2411083783694771,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018196746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98755985,0.001221151,0.0061120824,0.00019825519,0.00014041341,0.00031649077,0.0003916725,0.00013695056,0.0039230804],"genre_scores_gemma":[0.9898707,0.0010206556,0.0042772116,0.00004601877,0.000023584764,0.00016583568,0.00034270645,0.000037333084,0.0042159962],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996971,0.000043789547,0.000029176332,0.00006117596,0.000081494116,0.00008726649],"domain_scores_gemma":[0.9998648,0.0000592146,0.000020823183,0.000023768509,0.000011392222,0.000019853083],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046388552,0.00035218184,0.00042669877,0.0008272585,0.0003597298,0.00035168946,0.0003294186,0.00049034925,0.0027999468],"category_scores_gemma":[0.00027201427,0.0002220752,0.00037130134,0.00037478918,0.0006484635,0.0003489133,0.00024784106,0.00088224944,0.0004149691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007097272,0.0005177591,0.00044068744,0.00014870834,0.000034500343,0.00048168265,0.00022130254,0.0007408774,0.9871737,0.0024865442,0.00032894738,0.0067155906],"study_design_scores_gemma":[0.000104591454,0.00071436405,0.00053763,0.0000052954924,0.000038512728,0.00020631007,0.000046827427,0.0010396627,0.9943251,0.00013514695,0.0028433222,0.0000033196736],"about_ca_topic_score_codex":0.0034354108,"about_ca_topic_score_gemma":0.0039723394,"teacher_disagreement_score":0.0034354108,"about_ca_system_score_codex":0.00058394874,"about_ca_system_score_gemma":0.0006779989,"threshold_uncertainty_score":0.00936681},"labels":[],"label_agreement":null},{"id":"W2021285531","doi":"10.1038/sj.gt.3302839","title":"Efficient correction of Fabry mice and patient cells mediated by lentiviral transduction of hematopoietic stem/progenitor cells","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"CD34; Haematopoiesis; Progenitor cell; Biology; Bone marrow; Stem cell; Fabry disease; Globotriaosylceramide; Genetic enhancement; Viral vector; Transduction (biophysics); Immunology; Transplantation; Molecular biology; Cancer research; Cell biology; Internal medicine; Medicine; Recombinant DNA; Gene; Disease; Biochemistry","score_opus":0.007039856845197663,"score_gpt":0.22667427525176248,"score_spread":0.2196344184065648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021285531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9194691,0.0018429224,0.07195198,0.0003047764,0.00013006495,0.00023141078,0.00081474724,0.0012603761,0.003994635],"genre_scores_gemma":[0.97948474,0.0006246778,0.014011093,0.000051715426,0.000016180904,0.00004723626,0.00050991087,0.00019373829,0.005060711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99959,0.00008053651,0.00004465653,0.0000606479,0.00014547024,0.00007869318],"domain_scores_gemma":[0.9997634,0.00006116829,0.0000686094,0.000058674148,0.000018445779,0.000029577643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053738523,0.00057397457,0.000380022,0.0006092437,0.00021493282,0.00055522926,0.0003812216,0.0005724557,0.0013366432],"category_scores_gemma":[0.00039211952,0.00026766828,0.00030412173,0.00023496058,0.00038358656,0.00026519515,0.00037398722,0.00085038133,0.0005644877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003347232,0.00001194836,0.00010619843,0.00001578476,0.000004466386,0.00010071441,0.00002724726,0.00015086832,0.99624455,0.0010829156,0.000054538217,0.002167226],"study_design_scores_gemma":[0.000011093142,0.00004189723,0.0003628458,0.0000030351266,0.000010755709,0.0005536593,0.0000057552434,0.00095926813,0.9945239,0.000096275224,0.0034290133,0.0000025062336],"about_ca_topic_score_codex":0.0006111606,"about_ca_topic_score_gemma":0.00068243983,"teacher_disagreement_score":0.0013366432,"about_ca_system_score_codex":0.00040636075,"about_ca_system_score_gemma":0.00041880982,"threshold_uncertainty_score":0.004471481},"labels":[],"label_agreement":null},{"id":"W2022033453","doi":"10.1038/sj.gt.3302198","title":"Gene intervention in ligament and tendon: current status, challenges, future directions","year":2004,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Tendon Structure and Treatment","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Tendon; Gene transfer; Ligament; Genetic enhancement; Biology; Tendon transfer; Gene; Gene delivery; Bioinformatics; Anatomy; Genetics","score_opus":0.06560823487871624,"score_gpt":0.3697902091643469,"score_spread":0.30418197428563065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022033453","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007937887,0.9987288,0.00018471916,0.0003419538,0.00016132602,0.0000030925642,0.0000059438507,0.000006005925,0.0004887544],"genre_scores_gemma":[0.00034321053,0.9986426,0.00028934234,0.00021118067,0.00012814105,0.0000049465975,0.00000986565,0.0000013224311,0.00036926242],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99965525,0.00006682486,0.00005340083,0.0000689461,0.000116934054,0.000038683746],"domain_scores_gemma":[0.99873596,0.0008265499,0.00010343576,0.000030882053,0.00022548901,0.00007763918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001839354,0.0011489585,0.0032563182,0.002196997,0.00045330042,0.002137426,0.0016021942,0.0025349378,0.004194457],"category_scores_gemma":[0.0014932738,0.00040167934,0.0006789329,0.0029977043,0.0012392824,0.0025650654,0.0007674028,0.0030255946,0.0025971283],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018900797,0.0001877318,0.0002627048,0.014292571,0.000086231325,0.00026718684,0.00009622524,0.00048759513,0.0027521423,0.0036838655,0.02218978,0.9555049],"study_design_scores_gemma":[0.00007184474,0.00023685544,0.0010135662,0.007134076,0.00020084836,0.0016398809,0.00028684913,0.00021636387,0.00097024674,0.0030023868,0.9851869,0.000040294253],"about_ca_topic_score_codex":0.0021560467,"about_ca_topic_score_gemma":0.0051619415,"teacher_disagreement_score":0.004194457,"about_ca_system_score_codex":0.0009244983,"about_ca_system_score_gemma":0.0021106286,"threshold_uncertainty_score":0.014031887},"labels":[],"label_agreement":null},{"id":"W2023594496","doi":"10.1038/sj.gt.3303098","title":"Loading of oncolytic vesicular stomatitis virus onto antigen-specific T cells enhances the efficacy of adoptive T-cell therapy of tumors","year":2008,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Cancer Institute","keywords":"Oncolytic virus; Vesicular stomatitis virus; Virotherapy; Antigen; Immune system; Biology; Adoptive cell transfer; T cell; Virology; Immunotherapy; Cancer research; Immunology; Virus","score_opus":0.025531361303244213,"score_gpt":0.2741321566038207,"score_spread":0.24860079530057647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023594496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99422294,0.0011520846,0.0029334496,0.0000838717,0.000040299772,0.000023714656,0.00006797594,0.00011299267,0.0013626841],"genre_scores_gemma":[0.99672407,0.00046729256,0.0012920566,0.000029166564,0.000020338177,0.000011401103,0.000084902094,0.000041048337,0.0013296701],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99967647,0.000060617294,0.000023935552,0.000046760946,0.00008913157,0.00010311782],"domain_scores_gemma":[0.999726,0.00010736442,0.000041934753,0.0000499429,0.000024043167,0.000050659673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032358515,0.0005270321,0.00047414395,0.00036978116,0.0002041605,0.0008019361,0.00022120644,0.0005125991,0.0012515844],"category_scores_gemma":[0.00030881847,0.00022911622,0.00033350315,0.00025226464,0.00044316376,0.00049091165,0.0002824568,0.0010781017,0.00049384806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011135829,0.00006276234,0.00006371265,0.000019495095,0.0000052007767,0.000017322604,0.000018160132,0.00015554657,0.99794203,0.00018608622,0.00003482078,0.0013834328],"study_design_scores_gemma":[0.000012962549,0.00017518894,0.00034644883,0.0000023441191,0.000012287099,0.000036151698,0.0000050076123,0.0005706636,0.99836713,0.000027320499,0.00044235477,0.0000021332519],"about_ca_topic_score_codex":0.0005441627,"about_ca_topic_score_gemma":0.00054454664,"teacher_disagreement_score":0.0012515844,"about_ca_system_score_codex":0.00041596242,"about_ca_system_score_gemma":0.00036584085,"threshold_uncertainty_score":0.0041869283},"labels":[],"label_agreement":null},{"id":"W2026775720","doi":"10.1038/sj.gt.3303085","title":"Significant alterations of biodistribution and immune responses in Balb/c mice administered with adenovirus targeted to CD40(+) cells","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada; University of Ottawa; Health Canada","funders":"National Institute of Allergy and Infectious Diseases; Health Canada; U.S. Public Health Service; National Cancer Institute; Public Health Agency of Canada; National Institutes of Health; Public Health Agency","keywords":"Immune system; Adenoviridae; Biology; Genetic enhancement; Spleen; Transgene; Viral vector; Immunology; Biodistribution; Virology; Antigen; CD40; Cytotoxic T cell; In vivo; Gene","score_opus":0.016744988402320502,"score_gpt":0.2562379177049153,"score_spread":0.23949292930259478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026775720","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915776,0.0012435738,0.0040358035,0.00017177487,0.000088879,0.00005582599,0.0007637621,0.0002188237,0.0018439266],"genre_scores_gemma":[0.9873431,0.0008220881,0.0029088946,0.00011263084,0.00002770235,0.00008996051,0.00076433003,0.00010575847,0.007825632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996872,0.000036575417,0.000023716562,0.000086306216,0.00005020715,0.00011603331],"domain_scores_gemma":[0.99952626,0.00011066287,0.000113757145,0.000072986564,0.000053168988,0.00012312298],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036067856,0.0008588622,0.0005023537,0.0006520937,0.00025565227,0.00056264846,0.0003409638,0.00089913706,0.0015436198],"category_scores_gemma":[0.00027603656,0.00032525283,0.0003903993,0.00029610697,0.0007462896,0.00061683194,0.0002100701,0.001381814,0.00053148967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005161588,0.000060902614,0.00010196195,0.000019899455,0.0000041668545,0.000053285457,0.000024829336,0.000046773337,0.9985044,0.00010931422,0.0000215092,0.0005369117],"study_design_scores_gemma":[0.00002979934,0.0006002168,0.0016851407,0.000003494239,0.000025208692,0.00017112361,0.000030095018,0.00042425055,0.9963057,0.00006365618,0.00065324176,0.000008102351],"about_ca_topic_score_codex":0.0014014629,"about_ca_topic_score_gemma":0.0010653203,"teacher_disagreement_score":0.0015436198,"about_ca_system_score_codex":0.00044047818,"about_ca_system_score_gemma":0.00048676875,"threshold_uncertainty_score":0.005163908},"labels":[],"label_agreement":null},{"id":"W2027385673","doi":"10.1038/gt.2009.60","title":"Chitosan–plasmid nanoparticle formulations for IM and SC delivery of recombinant FGF-2 and PDGF-BB or generation of antibodies","year":2009,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Polytechnique Montréal","funders":"Canadian Institutes of Health Research","keywords":"Recombinant DNA; Gene delivery; Chitosan; Genetic enhancement; Glucosamine; DNA vaccination; Molecular biology; Growth factor; Biology; Chemistry; Biochemistry; Gene; Receptor","score_opus":0.039308536554448735,"score_gpt":0.2868443076090782,"score_spread":0.24753577105462946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027385673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89334995,0.003626691,0.08802633,0.00044405556,0.00028040574,0.0004581326,0.0005640036,0.000553358,0.012697036],"genre_scores_gemma":[0.94193345,0.0016943703,0.04039417,0.00015039451,0.000036036246,0.00020522723,0.00058908516,0.00011989136,0.014877357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985933,0.000013820318,0.00001118305,0.000029558316,0.000052255866,0.00003386816],"domain_scores_gemma":[0.9998847,0.000031019732,0.000029050165,0.000012803525,0.000028630182,0.000013798438],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002565709,0.0004911115,0.00021612245,0.00035265103,0.0002494705,0.00030083567,0.00023232016,0.00037603482,0.0018967106],"category_scores_gemma":[0.00025075534,0.00018652788,0.00029365296,0.0003568711,0.0002457366,0.00021652321,0.00015333194,0.0004958511,0.00045991008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041865416,0.000012570697,0.00002526218,0.00005298466,0.000004955369,0.000023507471,0.0000129755235,0.00008767784,0.99711597,0.00020019231,0.00011272432,0.0023093307],"study_design_scores_gemma":[0.000009373733,0.000064797176,0.00014784305,0.0000023759033,0.000013727239,0.000045737354,0.0000037195,0.00042319868,0.99719775,0.00001902575,0.0020690484,0.0000034930144],"about_ca_topic_score_codex":0.0023074665,"about_ca_topic_score_gemma":0.005267772,"teacher_disagreement_score":0.0023074665,"about_ca_system_score_codex":0.0007279526,"about_ca_system_score_gemma":0.0004716775,"threshold_uncertainty_score":0.006345153},"labels":[],"label_agreement":null},{"id":"W2027516733","doi":"10.1038/sj.gt.3302538","title":"A novel adenoviral vector which mediates hypoxia-inducible gene expression selectively in neurons","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences; National Research Council Canada","funders":"","keywords":"Biology; Reporter gene; Gene expression; Cell culture; Cell biology; Viral vector; Gene; Neuron; Regulation of gene expression; Hypoxia (environmental); Genetic enhancement; Molecular biology; Neuroscience; Genetics; Recombinant DNA; Chemistry","score_opus":0.01674086767429197,"score_gpt":0.253987834113473,"score_spread":0.237246966439181,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027516733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.840516,0.006526782,0.13591287,0.0011749389,0.0008236313,0.00071454165,0.0022374534,0.0012557794,0.010838036],"genre_scores_gemma":[0.86672604,0.005037976,0.10527181,0.00021274382,0.00010110223,0.00045870963,0.0028717145,0.00019854675,0.019121302],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998196,0.000020613736,0.000024799998,0.000037069425,0.000050915078,0.000047083762],"domain_scores_gemma":[0.9998498,0.00003266308,0.000026269234,0.000019995123,0.000019915193,0.000051381532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031472978,0.0005421878,0.0005016297,0.0003626001,0.00038736366,0.00058979145,0.0005960606,0.00055532245,0.0015087079],"category_scores_gemma":[0.0001699359,0.0002904033,0.0003816934,0.00029131284,0.00034703664,0.000538416,0.00032616575,0.0011945376,0.0004062432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016441428,0.000051456747,0.00006439642,0.00007162911,0.000008927008,0.000106475854,0.000034507666,0.00008680151,0.99260724,0.0018973475,0.0002230822,0.0046838364],"study_design_scores_gemma":[0.000100029036,0.0002954943,0.000602411,0.00001543909,0.000055402514,0.0005608342,0.000024461537,0.0011717337,0.9844577,0.00024654297,0.012458282,0.000011748062],"about_ca_topic_score_codex":0.0015514045,"about_ca_topic_score_gemma":0.0022761489,"teacher_disagreement_score":0.0015514045,"about_ca_system_score_codex":0.0006266231,"about_ca_system_score_gemma":0.00079202757,"threshold_uncertainty_score":0.0050471425},"labels":[],"label_agreement":null},{"id":"W2029194129","doi":"10.1038/sj.gt.3301274","title":"IL-12 plasmid-enhanced DNA vaccination against carcinoembryonic antigen (CEA) studied in immune-gene knockout mice","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Perforin; CTL*; Biology; CD8; Cytotoxic T cell; Immune system; Immunology; Carcinoembryonic antigen; Antigen; Fas ligand; Cancer research; Cancer; Apoptosis","score_opus":0.01377738136950729,"score_gpt":0.24167457182224775,"score_spread":0.22789719045274046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029194129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99386203,0.0009240856,0.0034354646,0.00014309726,0.000093881106,0.00009722121,0.0003407496,0.00015061277,0.0009529216],"genre_scores_gemma":[0.9937168,0.0008148856,0.0019282806,0.000070225426,0.000035460045,0.00011122137,0.000336617,0.0000509885,0.0029356957],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963045,0.00007003426,0.000025898076,0.000072683324,0.000050669423,0.00015028668],"domain_scores_gemma":[0.99969125,0.0000795638,0.000090355046,0.00003325251,0.000026566995,0.00007902394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032370858,0.0007068655,0.000590031,0.0006801812,0.00022604717,0.00029836892,0.0003430595,0.00083657523,0.0014828743],"category_scores_gemma":[0.00023758452,0.00034348413,0.0005732515,0.0002552847,0.0007148192,0.00051380903,0.00014686282,0.0014091127,0.00051924895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077062513,0.0002072913,0.000093067734,0.00003273369,0.00000597264,0.00007068569,0.000016216763,0.00008918158,0.99808097,0.00013077614,0.000027166752,0.00047529704],"study_design_scores_gemma":[0.00013449145,0.0022680215,0.0011171489,0.0000049846217,0.000043929205,0.00021138106,0.000017261395,0.0006725487,0.9948001,0.0000627604,0.00066272006,0.0000047905655],"about_ca_topic_score_codex":0.0007952099,"about_ca_topic_score_gemma":0.00057212217,"teacher_disagreement_score":0.0014828743,"about_ca_system_score_codex":0.0003754751,"about_ca_system_score_gemma":0.00027876432,"threshold_uncertainty_score":0.004960716},"labels":[],"label_agreement":null},{"id":"W2030221457","doi":"10.1038/sj.gt.3302107","title":"Development of a size-restricted pIX-deleted helper virus for amplification of helper-dependent adenovirus vectors","year":2004,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; McMaster University","funders":"","keywords":"Helper virus; Virus; Transgene; Biology; Virology; Adenoviridae; DNA; Molecular biology; Viral replication; Genetic enhancement; Gene; Genetics","score_opus":0.03442305258156858,"score_gpt":0.30730562853425913,"score_spread":0.27288257595269055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030221457","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.40036282,0.0026016792,0.58583283,0.00030345205,0.00027471324,0.0011570432,0.0016077525,0.0017348309,0.006124819],"genre_scores_gemma":[0.5829505,0.0029124832,0.3930203,0.00010807471,0.00006443276,0.00090751355,0.005637699,0.00044455045,0.013954462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997383,0.000031124167,0.000026103713,0.00007044455,0.00008914253,0.000044904027],"domain_scores_gemma":[0.9997209,0.00007882223,0.00004328966,0.000037469865,0.000048248265,0.000071311086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062465604,0.00076679717,0.00046051215,0.00075046875,0.00035867403,0.0005174019,0.0007598204,0.00043205102,0.0011786968],"category_scores_gemma":[0.00038108643,0.00063810707,0.0004430256,0.0003221661,0.00034515318,0.00048283336,0.0004489468,0.0014219654,0.0010872227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004931789,0.000026547345,0.00010076221,0.000055910874,0.0000065650343,0.000039326773,0.000030011419,0.00010713854,0.99425286,0.0007875961,0.000080816746,0.004463208],"study_design_scores_gemma":[0.0000229162,0.00013096273,0.00048805604,0.0000073607443,0.000022616108,0.00026897472,0.000011871625,0.0010016399,0.9908202,0.00015465582,0.0070619932,0.000008701394],"about_ca_topic_score_codex":0.0005542133,"about_ca_topic_score_gemma":0.00082022394,"teacher_disagreement_score":0.0011786968,"about_ca_system_score_codex":0.00045597675,"about_ca_system_score_gemma":0.0007799199,"threshold_uncertainty_score":0.003943205},"labels":[],"label_agreement":null},{"id":"W2035316404","doi":"10.1038/sj.gt.3301998","title":"Recombinant Sendai virus vectors for activated T lymphocytes","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Atomic Energy of Canada Limited","keywords":"Sendai virus; Biology; Genetic enhancement; Antigen; Gene delivery; Transduction (biophysics); Virology; Molecular biology; T cell; Cell biology; Virus; Immunology; Gene; Immune system; Genetics","score_opus":0.026620147810092712,"score_gpt":0.3029300476778354,"score_spread":0.2763098998677427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035316404","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.34281623,0.015973985,0.59011966,0.0011888609,0.0020506138,0.0024890816,0.0045717168,0.0060954215,0.034694426],"genre_scores_gemma":[0.5876184,0.016328411,0.28286812,0.0003156823,0.0005130137,0.0023077219,0.0096450895,0.000992606,0.099410824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995578,0.000088176,0.000032742348,0.00005375686,0.00019993869,0.00006751371],"domain_scores_gemma":[0.99969316,0.00010551755,0.000056286546,0.00005419708,0.000040198873,0.00005073759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005594277,0.0009715363,0.00051833363,0.0010887785,0.00056151405,0.0008573589,0.000614037,0.00074908265,0.0049880506],"category_scores_gemma":[0.0005548716,0.00051890756,0.00052871037,0.00075113203,0.0004659,0.0007791233,0.00040097957,0.0025324624,0.004460373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038033197,0.00009840766,0.000106093175,0.00027429656,0.00001940865,0.00015258619,0.00014220306,0.00013294483,0.97588056,0.0072020213,0.0015481174,0.014063042],"study_design_scores_gemma":[0.00010161453,0.00027067636,0.00030168984,0.000025283605,0.00006036093,0.00042713888,0.000029494002,0.0006902918,0.96127117,0.001372887,0.03543379,0.000015555208],"about_ca_topic_score_codex":0.00032556307,"about_ca_topic_score_gemma":0.0005150258,"teacher_disagreement_score":0.0049880506,"about_ca_system_score_codex":0.00049914664,"about_ca_system_score_gemma":0.0005350635,"threshold_uncertainty_score":0.016686678},"labels":[],"label_agreement":null},{"id":"W2036635645","doi":"10.1038/gt.2008.86","title":"Isolation of myogenic progenitor populations from Pax7-deficient skeletal muscle based on adhesion characteristics","year":2008,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Biology; Progenitor cell; Cell biology; PAX3; Population; Skeletal muscle; Stem cell; Myocyte; Immunology; Genetics; Anatomy; Gene; Transcription factor","score_opus":0.02532257150869906,"score_gpt":0.2546790377077124,"score_spread":0.22935646619901331,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036635645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9647626,0.0019203626,0.023029177,0.00019485912,0.000086944834,0.0007957325,0.0012456167,0.000120261204,0.007844458],"genre_scores_gemma":[0.95868975,0.0014738031,0.022092568,0.0002565748,0.00005343896,0.0007556123,0.0028429057,0.00013236933,0.01370297],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997794,0.000022148337,0.0000276201,0.0000364226,0.00007927648,0.000055154476],"domain_scores_gemma":[0.9997212,0.00011078194,0.000024287638,0.000032322503,0.00004173001,0.00006964544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004487021,0.00028038147,0.00040971427,0.0007428132,0.00040466932,0.0005862975,0.00049711205,0.00039840274,0.0021122058],"category_scores_gemma":[0.00031775984,0.0003049867,0.00034038944,0.00037079342,0.00019960596,0.0002321612,0.00058383186,0.0012931579,0.0010221428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015606258,0.00008143494,0.00031208186,0.000024080642,0.000010437918,0.00006494721,0.000050240804,0.000069339585,0.9965771,0.00036676018,0.00007320745,0.002214268],"study_design_scores_gemma":[0.00010031462,0.00034379357,0.0056394776,0.00002170832,0.00007690823,0.00040294844,0.000084017905,0.0024742456,0.98678154,0.0002166211,0.003850008,0.000008361987],"about_ca_topic_score_codex":0.0005875976,"about_ca_topic_score_gemma":0.0013921798,"teacher_disagreement_score":0.0021122058,"about_ca_system_score_codex":0.00015413114,"about_ca_system_score_gemma":0.00019857216,"threshold_uncertainty_score":0.007066071},"labels":[],"label_agreement":null},{"id":"W2037206324","doi":"10.1038/sj.gt.3302907","title":"Plasmid-based gene therapy of diabetes mellitus","year":2007,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Krembil Foundation","keywords":"Genetic enhancement; Immune system; Biology; Immunology; Glucose homeostasis; Islet; Antigen; Immune tolerance; DNA vaccination; Gene delivery; Diabetes mellitus; Endocrinology; Gene; Insulin resistance; Genetics; Immunization","score_opus":0.05274247453423182,"score_gpt":0.3264402536591247,"score_spread":0.2736977791248929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037206324","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00035425863,0.99433315,0.0020782826,0.00029472326,0.00056050334,0.0000138915875,0.000027725673,0.000035310084,0.0023022168],"genre_scores_gemma":[0.0017115658,0.99449337,0.0012628294,0.00023431997,0.0001829296,0.000018331335,0.00005612417,0.0000058681335,0.0020346271],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99985945,0.0000205307,0.000013967223,0.000022720864,0.000067719964,0.000015641159],"domain_scores_gemma":[0.9998629,0.00006813472,0.000019168785,0.000007142953,0.000030404475,0.00001218053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053913496,0.0009149702,0.0013378832,0.0016077904,0.00022205782,0.0007989838,0.0011470196,0.0010319459,0.0019896093],"category_scores_gemma":[0.00038020662,0.00029118956,0.0003876821,0.0016469494,0.0006162687,0.0009011548,0.00044255078,0.0018842256,0.0020027643],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105370455,0.00014904805,0.000091699825,0.0062801237,0.000067804925,0.00039118784,0.000046726025,0.00054456946,0.012405696,0.0068410677,0.028469756,0.9446069],"study_design_scores_gemma":[0.00004795229,0.00010577312,0.00038408794,0.0009472431,0.00009131885,0.0015625906,0.00002832703,0.00018351513,0.0042681284,0.0024232268,0.9899372,0.000020602396],"about_ca_topic_score_codex":0.00070603576,"about_ca_topic_score_gemma":0.0011814187,"teacher_disagreement_score":0.0019896093,"about_ca_system_score_codex":0.000612519,"about_ca_system_score_gemma":0.00050561747,"threshold_uncertainty_score":0.006655872},"labels":[],"label_agreement":null},{"id":"W2037501805","doi":"10.1038/sj.gt.3301308","title":"Stabilized plasmid-lipid particles for systemic gene therapy","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":148,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Inimex Pharmaceuticals (Canada)","funders":"","keywords":"Plasmid; Genetic enhancement; Molecular biology; Gene delivery; Transfection; Liposome; Cationic liposome; DNA; Gene; Biology; Vector (molecular biology); Chemistry; Biochemistry; Recombinant DNA","score_opus":0.023255051457358622,"score_gpt":0.26142748739043004,"score_spread":0.2381724359330714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037501805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5403313,0.018793538,0.42489767,0.0009151616,0.000443073,0.0006203885,0.0007523199,0.0019151301,0.011331289],"genre_scores_gemma":[0.89493614,0.008168839,0.07864757,0.00017756423,0.00007080106,0.0004294726,0.0008839636,0.0003709318,0.01631462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998753,0.000021000615,0.0000075825847,0.000021692616,0.000052078693,0.000022309632],"domain_scores_gemma":[0.99992347,0.000025580279,0.000016680668,0.00001075434,0.000010503213,0.000012996878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030506085,0.00043412801,0.0004850314,0.0004642865,0.0002802636,0.00038896888,0.00027020517,0.00050354504,0.0013651658],"category_scores_gemma":[0.0001882309,0.00025239072,0.00024647973,0.00033959612,0.00041326863,0.0003764776,0.00035688982,0.00088139495,0.00075467816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006510937,0.000017009255,0.000032259493,0.000086387045,0.000005256744,0.000047440408,0.000023732775,0.00012764489,0.9930316,0.0014513215,0.00015152422,0.004960661],"study_design_scores_gemma":[0.000019434696,0.00009054705,0.0001281449,0.000005377723,0.00001363807,0.000116211064,0.000004853621,0.00045719647,0.9945912,0.0002687245,0.004299929,0.000004771961],"about_ca_topic_score_codex":0.00029654853,"about_ca_topic_score_gemma":0.0005420785,"teacher_disagreement_score":0.0013651658,"about_ca_system_score_codex":0.00043957718,"about_ca_system_score_gemma":0.00043492208,"threshold_uncertainty_score":0.004566908},"labels":[],"label_agreement":null},{"id":"W2039979117","doi":"10.1038/gt.2009.9","title":"A 16-bp RBE element mediated Rep-dependent site-specific integration in AAVS1 transgenic mice for expression of hFIX","year":2009,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Transgene; Biology; Factor IX; Genetic enhancement; Adeno-associated virus; Plasmid; In vivo; Molecular biology; Gene; Locus (genetics); Genetically modified mouse; Recombinant DNA; Genetics; Vector (molecular biology)","score_opus":0.026502066574009324,"score_gpt":0.30788805135108904,"score_spread":0.2813859847770797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039979117","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87416774,0.0023875474,0.10285355,0.0010665879,0.0005583626,0.0012063276,0.006229115,0.0032547745,0.008276045],"genre_scores_gemma":[0.8236828,0.0018348616,0.12497659,0.00033753982,0.00011781887,0.0008978394,0.0065638274,0.0011178823,0.04047086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993643,0.000110462235,0.00008893191,0.00017334698,0.00014513951,0.000117894546],"domain_scores_gemma":[0.9995309,0.000096239775,0.00014638262,0.00009024756,0.000031786276,0.000104377265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007865027,0.0010549644,0.000610688,0.0010797108,0.00042650296,0.00037345386,0.0012165711,0.0014550678,0.0054855975],"category_scores_gemma":[0.0003099866,0.0008702472,0.0010088836,0.0004133614,0.00080347125,0.0007082543,0.00047447826,0.00254784,0.0030301171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010019686,0.000048222377,0.000029435387,0.00004295045,0.0000064796955,0.00004662236,0.000017652803,0.000047800724,0.99814534,0.00035888056,0.000057898815,0.001098672],"study_design_scores_gemma":[0.000047796315,0.00015276409,0.00041425077,0.000012192842,0.000020768117,0.00022092425,0.0000059934027,0.00033571947,0.99490106,0.00006192934,0.00381724,0.000009285306],"about_ca_topic_score_codex":0.00047841307,"about_ca_topic_score_gemma":0.0010044422,"teacher_disagreement_score":0.0054855975,"about_ca_system_score_codex":0.000651266,"about_ca_system_score_gemma":0.0005724268,"threshold_uncertainty_score":0.018351138},"labels":[],"label_agreement":null},{"id":"W2040982254","doi":"10.1038/sj.gt.3302664","title":"RNAi: a potential therapy for the dominantly inherited nucleotide repeat diseases","year":2005,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke","keywords":"RNA interference; Biology; Trinucleotide repeat expansion; Genetics; Gene silencing; Myotonic dystrophy; Spinocerebellar ataxia; Genetic enhancement; Gene; Disease; microRNA; Bioinformatics; RNA; Allele; Medicine; Pathology","score_opus":0.08753284207737928,"score_gpt":0.3498675799030133,"score_spread":0.26233473782563405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040982254","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023953858,0.9930963,0.0017677895,0.0005578468,0.00074627006,0.000014540275,0.000038798033,0.000044687917,0.0034941968],"genre_scores_gemma":[0.0011392232,0.99312204,0.0014766451,0.0005089339,0.00036214158,0.000024337824,0.00007313288,0.0000076248293,0.0032859119],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99984443,0.000021533137,0.000018732668,0.000029518493,0.00006909226,0.000016660033],"domain_scores_gemma":[0.999705,0.00013940867,0.000032402902,0.000010636237,0.00007586222,0.000036550508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00084576185,0.0017103308,0.0017842309,0.0021778014,0.00038578841,0.0011057078,0.0013252293,0.002138481,0.0030602117],"category_scores_gemma":[0.0004901512,0.00036131337,0.00048942026,0.0017523726,0.00095641194,0.001392642,0.0005552822,0.0032768443,0.0029179815],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012641112,0.00014674186,0.00010828128,0.0050245626,0.00008641207,0.00044915813,0.00004776043,0.00057201396,0.01000619,0.005988892,0.04981825,0.92762524],"study_design_scores_gemma":[0.000054115222,0.0001315536,0.00038602162,0.0008637203,0.00010769817,0.0016244332,0.00003175038,0.00018775983,0.0030499632,0.0027903419,0.99074215,0.000030462086],"about_ca_topic_score_codex":0.0014261241,"about_ca_topic_score_gemma":0.0031668292,"teacher_disagreement_score":0.0030602117,"about_ca_system_score_codex":0.0008568542,"about_ca_system_score_gemma":0.0007824301,"threshold_uncertainty_score":0.010237455},"labels":[],"label_agreement":null},{"id":"W2041189307","doi":"10.1038/gt.2011.142","title":"Gene therapy for retinal ganglion cell neuroprotection in glaucoma","year":2011,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Glaucoma; Neuroprotection; Retinal ganglion cell; Optic nerve; Neuroscience; Retina; Intraocular pressure; Ophthalmology; Biology; Retinal; Blindness; Retinal degeneration; Medicine; Optometry","score_opus":0.03100403014773893,"score_gpt":0.28019547386439564,"score_spread":0.24919144371665672,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041189307","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024713928,0.9969271,0.0006181736,0.00027062817,0.00038304887,0.0000084880885,0.000023497707,0.000013844701,0.0015080792],"genre_scores_gemma":[0.0013129847,0.99597317,0.00070680614,0.0002402891,0.00022667903,0.000014510522,0.0000455363,0.0000042097145,0.0014758456],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99988306,0.000017196759,0.000017913137,0.000020481612,0.000047843452,0.000013633602],"domain_scores_gemma":[0.99981683,0.00009655372,0.000022291868,0.000006650589,0.000041530326,0.000016186514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058680173,0.001046808,0.0014570465,0.001636451,0.0002436281,0.00073844934,0.0009326609,0.0011727432,0.0023286375],"category_scores_gemma":[0.000510148,0.00029485588,0.0004317883,0.0014366925,0.0006189036,0.0009955519,0.00048205504,0.0022080778,0.0015915275],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013979313,0.00013855586,0.00011867348,0.008692893,0.00009266297,0.00044995654,0.000052907548,0.00059314474,0.008367674,0.004960239,0.03856705,0.93782634],"study_design_scores_gemma":[0.00007822465,0.00012674624,0.0006013953,0.0015686734,0.00015892978,0.0019407797,0.000044972592,0.00019258179,0.0026705214,0.002552953,0.9900358,0.000028367807],"about_ca_topic_score_codex":0.0011109578,"about_ca_topic_score_gemma":0.0026402448,"teacher_disagreement_score":0.0023286375,"about_ca_system_score_codex":0.00059748057,"about_ca_system_score_gemma":0.00066878233,"threshold_uncertainty_score":0.007790029},"labels":[],"label_agreement":null},{"id":"W2041557765","doi":"10.1038/sj.gt.3302124","title":"Local immunotherapy of spontaneous feline fibrosarcomas using recombinant poxviruses expressing interleukin 2 (IL2)","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Willow Biosciences (Canada)","funders":"","keywords":"Vaccinia; Immunotherapy; Poxviridae; Context (archaeology); Immunology; Myxomatosis; Vaccination; Virology; Biology; Virus; Viral vector; Medicine; Cancer; Immune system; Recombinant DNA; Internal medicine","score_opus":0.03124393729798712,"score_gpt":0.30607899953115353,"score_spread":0.2748350622331664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041557765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99330515,0.0013244236,0.0030659274,0.00013645756,0.00006922677,0.00014698473,0.00007869267,0.00013223613,0.0017408448],"genre_scores_gemma":[0.9956103,0.0005852245,0.0013125214,0.000042442512,0.000039950024,0.0001010608,0.00014541476,0.000015940992,0.002147153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974924,0.00006147902,0.0000137177585,0.000052375184,0.000040924027,0.00008236945],"domain_scores_gemma":[0.99980277,0.00007594732,0.000044508022,0.000039808747,0.000008918819,0.000028126246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004994836,0.0005453684,0.00037889375,0.00035626808,0.0002586744,0.00033373313,0.00030395508,0.0007367114,0.001156252],"category_scores_gemma":[0.00023116899,0.00018115362,0.00043643088,0.00011661526,0.0004641358,0.00040669192,0.0002444096,0.0010807342,0.0002851485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000522903,0.00048962794,0.00027951185,0.00009371318,0.000014521897,0.00032376943,0.00008138527,0.0003718565,0.9933548,0.00043442057,0.000107985165,0.003925399],"study_design_scores_gemma":[0.00029798003,0.0050498997,0.0014774114,0.000018236802,0.00004676009,0.0012258944,0.000052527423,0.0015646425,0.9874636,0.00012079654,0.0026769766,0.000005377638],"about_ca_topic_score_codex":0.00027879197,"about_ca_topic_score_gemma":0.0004890705,"teacher_disagreement_score":0.001156252,"about_ca_system_score_codex":0.0002758984,"about_ca_system_score_gemma":0.00022309495,"threshold_uncertainty_score":0.0038679838},"labels":[],"label_agreement":null},{"id":"W2041705668","doi":"10.1038/gt.2011.105","title":"Development of optimized AAV3 serotype vectors: mechanism of high-efficiency transduction of human liver cancer cells","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; American Cancer Society; China Scholarship Council; National Center for Advancing Translational Sciences; University of Florida","keywords":"Transduction (biophysics); Biology; Signal transduction; Genetic enhancement; Tyrosine kinase; Mutant; Viral vector; Receptor tyrosine kinase; Cancer research; Transgene; Cancer cell; Molecular biology; Cell biology; Cancer; Gene; Biochemistry; Genetics","score_opus":0.04357385452592154,"score_gpt":0.289095423903261,"score_spread":0.24552156937733943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041705668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7651983,0.002442895,0.22641806,0.0003658797,0.00014652869,0.0005057354,0.0014027858,0.0008545269,0.0026652939],"genre_scores_gemma":[0.83826745,0.0018964879,0.15199916,0.000115541836,0.000025248899,0.00022493929,0.0021673935,0.00028276013,0.0050209896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997801,0.000037086313,0.000025785128,0.000033649463,0.0000823716,0.000041106945],"domain_scores_gemma":[0.9998597,0.00002185322,0.000036945054,0.00001710721,0.000033215038,0.000031113348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005265112,0.00044253242,0.00032761926,0.000286472,0.00019961053,0.00043824918,0.0003102178,0.00036070694,0.0007742023],"category_scores_gemma":[0.00021995149,0.00028270387,0.00039254272,0.0002660453,0.0002625265,0.0003213771,0.00018001908,0.00079717534,0.0003581673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061858475,0.000017873934,0.00013729493,0.00003208909,0.0000068369322,0.00003071069,0.000019980245,0.00024741076,0.996166,0.00065415225,0.00009851791,0.0025272302],"study_design_scores_gemma":[0.000012300497,0.00007347201,0.0005735202,0.0000022314514,0.000011440267,0.00014285852,0.0000057910697,0.0011798133,0.99539787,0.00009937302,0.002494388,0.0000070360625],"about_ca_topic_score_codex":0.0011966582,"about_ca_topic_score_gemma":0.0017028586,"teacher_disagreement_score":0.0011966582,"about_ca_system_score_codex":0.00067916035,"about_ca_system_score_gemma":0.0007324775,"threshold_uncertainty_score":0.004927695},"labels":[],"label_agreement":null},{"id":"W2041801904","doi":"10.1038/sj.gt.3302074","title":"Illegitimate DNA integration in mammalian cells","year":2003,"lang":"en","type":"review","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University; Université de Montréal","funders":"","keywords":"Biology; Genome; Genetics; DNA; Computational biology; Locus (genetics); Gene; Genome instability; DNA damage","score_opus":0.02180882947428856,"score_gpt":0.3355680229535563,"score_spread":0.31375919347926773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041801904","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001188344,0.97858596,0.011972978,0.0004844129,0.0009247585,0.00003306958,0.000053377684,0.00018351528,0.006573621],"genre_scores_gemma":[0.0076313526,0.97666514,0.0056106686,0.0005049122,0.00025399358,0.000053051455,0.00014115291,0.00002407116,0.0091157295],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997384,0.00003720336,0.00002905644,0.00004943355,0.00011817264,0.000027683443],"domain_scores_gemma":[0.9998766,0.000060561706,0.000017508915,0.000012405184,0.000021767435,0.000011119235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005357675,0.0011279157,0.0016818767,0.0012100507,0.00032360334,0.001033177,0.001499635,0.0014641498,0.0019592238],"category_scores_gemma":[0.00032254012,0.00030004256,0.0003519954,0.0012036081,0.00103408,0.00082887255,0.00050628907,0.0016293754,0.0024993299],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009434796,0.00011157778,0.0001239217,0.0056124446,0.00004217824,0.00052914745,0.00008800011,0.0006962069,0.055797927,0.010675706,0.016947338,0.9092812],"study_design_scores_gemma":[0.00002826803,0.00009035198,0.00032508635,0.0006068914,0.00006982573,0.002467295,0.00004386647,0.00024921016,0.03641643,0.0035086733,0.9561694,0.000024668514],"about_ca_topic_score_codex":0.0007796465,"about_ca_topic_score_gemma":0.0012727713,"teacher_disagreement_score":0.0019592238,"about_ca_system_score_codex":0.00076057314,"about_ca_system_score_gemma":0.0004902324,"threshold_uncertainty_score":0.0065543056},"labels":[],"label_agreement":null},{"id":"W2041994416","doi":"10.1038/sj.gt.3302887","title":"Dystrophin expression in host muscle following transplantation of muscle precursor cells modified with the phiC31 integrase","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Dystrophin; Duchenne muscular dystrophy; Nucleofection; Biology; Transplantation; Transgene; Muscular dystrophy; Integrase; Transfection; Genetic enhancement; Molecular biology; Cell biology; Myogenesis; Myocyte; Gene; Genetics; Medicine; Internal medicine","score_opus":0.006896995521748498,"score_gpt":0.21892155305243027,"score_spread":0.21202455753068178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041994416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99701273,0.00057310425,0.0010175139,0.000038777805,0.000024912075,0.000015389098,0.000119069184,0.000023693932,0.0011746861],"genre_scores_gemma":[0.99508744,0.00030141536,0.0009110883,0.000029714347,0.000007749041,0.000016459662,0.0002943323,0.000024381547,0.0033273906],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997712,0.00003379233,0.000020427435,0.00004852693,0.00005776973,0.00006837536],"domain_scores_gemma":[0.99978155,0.00006564772,0.0000533235,0.000024382913,0.000015592135,0.00005957989],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000283469,0.0002879704,0.00032560623,0.00022880995,0.0002237551,0.0004503832,0.00022366298,0.0005473154,0.0009660937],"category_scores_gemma":[0.00016891203,0.0001782895,0.00022128534,0.00019769689,0.00037807648,0.00029826656,0.00022767873,0.0008142142,0.00022247639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011885666,0.000017992721,0.00006167343,0.000012179826,0.000002461696,0.000053636948,0.000020314728,0.00003260097,0.9992656,0.00010527144,0.000010710043,0.0002986834],"study_design_scores_gemma":[0.000027003794,0.0003959758,0.0030465676,0.000005942087,0.000021513437,0.00028838296,0.000048438298,0.0006727577,0.9945476,0.000053535172,0.00088811264,0.000004276045],"about_ca_topic_score_codex":0.0007433337,"about_ca_topic_score_gemma":0.0010807825,"teacher_disagreement_score":0.0009660937,"about_ca_system_score_codex":0.00029970863,"about_ca_system_score_gemma":0.00022969826,"threshold_uncertainty_score":0.0032319427},"labels":[],"label_agreement":null},{"id":"W2042141901","doi":"10.1038/sj.gt.3302357","title":"Transbronchial administration of adenoviral-mediated interleukin-10 gene to the donor improves function in a pig lung transplant model","year":2004,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"Genetic enhancement; Lung transplantation; Lung; Transplantation; Gene delivery; Immunology; Medicine; Reperfusion injury; Viral vector; Transfection; Systemic administration; Cancer research; Ischemia; Biology; Gene; In vivo; Internal medicine; Recombinant DNA","score_opus":0.01092358019237522,"score_gpt":0.23802732470606378,"score_spread":0.22710374451368856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042141901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99102587,0.0014607101,0.0049382495,0.00037188566,0.00026832052,0.00006550823,0.00017196884,0.00024828187,0.0014492142],"genre_scores_gemma":[0.9918099,0.0010109427,0.0023951335,0.00014234563,0.000041559593,0.000068785215,0.00032946575,0.000048433387,0.004153371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997098,0.000073742296,0.000024694806,0.000059736616,0.000058111855,0.000073874704],"domain_scores_gemma":[0.9995421,0.000105902,0.000106874184,0.00007427483,0.000027036305,0.00014379052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071432407,0.0007828134,0.0009056433,0.0006233645,0.00034224353,0.0005377885,0.0006650866,0.00087711465,0.0017546547],"category_scores_gemma":[0.00029884494,0.00024433437,0.00050674536,0.0001894777,0.001070722,0.0007220784,0.00021683123,0.0014359034,0.00045024155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001046767,0.00050559937,0.00017177578,0.00006093196,0.000013249351,0.00023636207,0.000034464367,0.000098427634,0.99531674,0.00017464202,0.00011948765,0.0022215317],"study_design_scores_gemma":[0.00022027826,0.008807413,0.0032198285,0.00002800799,0.000098733115,0.001113313,0.00008439302,0.0012922579,0.9835956,0.00015642607,0.0013658365,0.000017824656],"about_ca_topic_score_codex":0.00048618123,"about_ca_topic_score_gemma":0.0005550645,"teacher_disagreement_score":0.0017546547,"about_ca_system_score_codex":0.00032239562,"about_ca_system_score_gemma":0.0003859133,"threshold_uncertainty_score":0.0058698654},"labels":[],"label_agreement":null},{"id":"W2043850625","doi":"10.1038/gt.2012.61","title":"Efficient transduction of myeloid cells by an HIV-1-derived lentiviral vector that packages the Vpx accessory protein","year":2012,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; U.S. Public Health Service; Oncolytics Biotech","keywords":"SAMHD1; Transduction (biophysics); Viral vector; Biology; Small hairpin RNA; Virology; Gene knockdown; Multiplicity of infection; Lentivirus; Genetic enhancement; Myeloid; RNA interference; Molecular biology; Cell culture; Gene; RNA; Cancer research; Virus; Reverse transcriptase; Genetics; Recombinant DNA","score_opus":0.026690100686190623,"score_gpt":0.2827094046993965,"score_spread":0.2560193040132059,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043850625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9272683,0.0018647908,0.06416501,0.00027683878,0.00012032584,0.0002608076,0.0009157981,0.0004014489,0.0047265063],"genre_scores_gemma":[0.96681845,0.0010084782,0.024695164,0.00005546043,0.000024342935,0.00010152442,0.00090343645,0.00007750731,0.0063156732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997389,0.000041321186,0.000023045313,0.000037419188,0.00008816253,0.00007120349],"domain_scores_gemma":[0.99989295,0.000016947148,0.000027622764,0.00002106847,0.000013274671,0.000028122855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003922932,0.0004465005,0.00024856094,0.00031006787,0.0002454867,0.0007734188,0.00024796682,0.00035246383,0.0011301273],"category_scores_gemma":[0.00019198864,0.00017037446,0.00025583367,0.00022995748,0.0003240513,0.000396247,0.00037175117,0.0011982472,0.00055060926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045723686,0.000017750204,0.00010160809,0.000019302774,0.0000039725746,0.000043121996,0.000024994824,0.00006972914,0.99615854,0.0013319823,0.000055958822,0.002127496],"study_design_scores_gemma":[0.000018223132,0.00008348749,0.00071949826,0.0000066024363,0.000009730568,0.00022883069,0.000012729078,0.0009234809,0.99325764,0.00022679886,0.004509146,0.000003850278],"about_ca_topic_score_codex":0.0004782909,"about_ca_topic_score_gemma":0.00067918625,"teacher_disagreement_score":0.0011301273,"about_ca_system_score_codex":0.0005141471,"about_ca_system_score_gemma":0.0005604431,"threshold_uncertainty_score":0.003780663},"labels":[],"label_agreement":null},{"id":"W2044592759","doi":"10.1038/sj.gt.3303100","title":"Progress and prospects: gene therapy for performance and appearance enhancement","year":2008,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; World Anti-Doping Agency","keywords":"Genetic enhancement; Performance enhancement; Human enhancement; Gene transfer; Hair growth; Reversing; Disease; Gene delivery; Psychological intervention; Cognition; Biology; Bioinformatics; Risk analysis (engineering); Psychology; Medicine; Neuroscience; Gene; Physical medicine and rehabilitation; Pathology; Genetics; Engineering; Physiology","score_opus":0.03873682208817798,"score_gpt":0.34483442682970916,"score_spread":0.3060976047415312,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044592759","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016017485,0.99630094,0.0006952044,0.00048711218,0.00053383014,0.000004514173,0.000009611783,0.000013584448,0.0017949917],"genre_scores_gemma":[0.0017063991,0.9938496,0.0011027647,0.000610194,0.0004158484,0.0000169696,0.000023141132,0.0000051255697,0.0022700438],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99980396,0.000035686247,0.000015052717,0.000042024698,0.000076971,0.000026298208],"domain_scores_gemma":[0.99975866,0.00014377313,0.00001810666,0.00000985921,0.000049501683,0.000020116238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074796705,0.0011727727,0.0016123165,0.0014244764,0.00043952104,0.0015015518,0.0012528725,0.0022641262,0.0035821383],"category_scores_gemma":[0.00058054714,0.00028804952,0.0004041348,0.0017093933,0.001246585,0.0022925765,0.0007233956,0.0028122037,0.0027819711],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107763066,0.00012998421,0.00016511627,0.007951071,0.000038651455,0.00036285433,0.00010994804,0.00062218384,0.012762056,0.024746198,0.04272145,0.9102827],"study_design_scores_gemma":[0.00001851723,0.000078146455,0.00026926163,0.00074734114,0.000029943703,0.0010643472,0.000081659855,0.00018329504,0.0024943678,0.007886189,0.98712385,0.000023129767],"about_ca_topic_score_codex":0.00093379675,"about_ca_topic_score_gemma":0.0015454045,"teacher_disagreement_score":0.0035821383,"about_ca_system_score_codex":0.0009487587,"about_ca_system_score_gemma":0.000991257,"threshold_uncertainty_score":0.011983514},"labels":[],"label_agreement":null},{"id":"W2045502630","doi":"10.1038/gt.2011.214","title":"BRCA1 gene therapy reduces systemic inflammatory response and multiple organ failure and improves survival in experimental sepsis","year":2012,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Vitamin C and Antioxidants Research","field":"Nursing","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Mount Sinai Hospital; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Sepsis; Multiple organ dysfunction syndrome; Systemic inflammation; Genetic enhancement; Medicine; Inflammation; Peritonitis; Immunology; Organ dysfunction; Perforation; Gene delivery; Systemic inflammatory response syndrome; Biology; Internal medicine; Gene","score_opus":0.024902534592476922,"score_gpt":0.29629771624908297,"score_spread":0.27139518165660603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045502630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99638474,0.0017120404,0.0006976184,0.00044267206,0.000087296445,0.000016160942,0.00010541718,0.000088724286,0.0004652781],"genre_scores_gemma":[0.9939406,0.0024590106,0.0010048337,0.00021916785,0.00005216472,0.000063135994,0.00024954605,0.000025874979,0.0019857597],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999261,0.000017948829,0.000004471337,0.000013142292,0.000014378123,0.000023877159],"domain_scores_gemma":[0.9998715,0.000025027672,0.00004065846,0.00001389232,0.000010080052,0.000038830105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019671535,0.00032388206,0.0005754182,0.00037118865,0.00020180034,0.00022916318,0.0002949245,0.00042905525,0.0017624351],"category_scores_gemma":[0.00031803077,0.00012215036,0.00024656596,0.00014985811,0.00049090205,0.00030065535,0.0001885057,0.00078326336,0.00018442866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018077511,0.0034001998,0.0016098479,0.0003372449,0.000120965175,0.00021460625,0.00010768258,0.00071668846,0.9196134,0.0004353285,0.001745072,0.053621557],"study_design_scores_gemma":[0.004203429,0.042193618,0.026598344,0.00013856897,0.00048589503,0.0010828759,0.00033643006,0.0031270704,0.91184306,0.0008093722,0.009118395,0.000062998],"about_ca_topic_score_codex":0.00071087864,"about_ca_topic_score_gemma":0.0005913216,"teacher_disagreement_score":0.0017624351,"about_ca_system_score_codex":0.00023768944,"about_ca_system_score_gemma":0.00035560265,"threshold_uncertainty_score":0.0058959723},"labels":[],"label_agreement":null},{"id":"W2047544039","doi":"10.1038/sj.gt.3302915","title":"Gene transfer in human skin with different pseudotyped HIV-based vectors","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"","keywords":"Virology; Vesicular stomatitis virus; Biology; Transduction (biophysics); Viral vector; Rabies virus; Tropism; Vector (molecular biology); Virus; Gene; Genetics","score_opus":0.01697629235174048,"score_gpt":0.28719716385903893,"score_spread":0.27022087150729845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047544039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96975535,0.004421904,0.021196758,0.00010515275,0.00024203901,0.0002487583,0.0004313088,0.0001353078,0.003463384],"genre_scores_gemma":[0.977384,0.0021966768,0.015184365,0.00005902566,0.000018793238,0.000115758776,0.00052375486,0.000053243934,0.004464429],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99958056,0.00011227315,0.00005033156,0.00009563238,0.00008048815,0.00008078707],"domain_scores_gemma":[0.9997726,0.00009002118,0.000028840412,0.00005452053,0.000028115985,0.000025879535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008325859,0.0003625474,0.00028519772,0.0004388499,0.00024810468,0.00064372766,0.00035003424,0.0006009727,0.0011428038],"category_scores_gemma":[0.00043946743,0.00022154434,0.00043405147,0.00030302597,0.00038769745,0.0005708304,0.00021284533,0.00085122365,0.00040759702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018916186,0.00003970474,0.00008976284,0.000060827006,0.000011503316,0.000089197754,0.000058863647,0.000088960915,0.9964406,0.00078597665,0.000035631685,0.0021098286],"study_design_scores_gemma":[0.000020385185,0.000291619,0.00037353867,0.0000074152726,0.0000336422,0.00026240695,0.000031629672,0.00041936166,0.99709845,0.00012850873,0.0013280445,0.000004961836],"about_ca_topic_score_codex":0.00043200754,"about_ca_topic_score_gemma":0.00032201226,"teacher_disagreement_score":0.0011428038,"about_ca_system_score_codex":0.00025790805,"about_ca_system_score_gemma":0.0003153521,"threshold_uncertainty_score":0.004403174},"labels":[],"label_agreement":null},{"id":"W2048324572","doi":"10.1038/sj.gt.3302712","title":"Readministration of helper-dependent adenovirus to mouse lung","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Transgene; Genetic enhancement; Lung; Immunology; Antibody; Adenoviridae; Cystic fibrosis; Biology; Respiratory disease; Immune system; Cytotoxic T cell; Medicine; Gene; Internal medicine; In vitro","score_opus":0.01927189592128105,"score_gpt":0.3054526362894368,"score_spread":0.2861807403681558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048324572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95756626,0.007031654,0.023274612,0.00045365168,0.0011715703,0.000732201,0.0013395762,0.0013684105,0.007062057],"genre_scores_gemma":[0.9653635,0.0025813393,0.011525537,0.0002005974,0.0003040443,0.00029275287,0.0019410488,0.000178697,0.01761245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924767,0.00013088457,0.000072258306,0.00016528627,0.000106420885,0.0002774846],"domain_scores_gemma":[0.99911124,0.00035835835,0.00011221251,0.00022083703,0.00006005421,0.0001373318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010944188,0.0011704398,0.0007747983,0.0011154201,0.00035797886,0.00068126945,0.0009212466,0.0010050897,0.002423978],"category_scores_gemma":[0.00057345233,0.00044060394,0.0008426082,0.0005460919,0.00055607135,0.0005295345,0.00027814048,0.0014845767,0.00059538806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015725967,0.0001857967,0.00030574529,0.00013693965,0.00002361354,0.00021053807,0.000053046067,0.00018770073,0.9928428,0.0007990217,0.00016010889,0.0035220634],"study_design_scores_gemma":[0.000039339648,0.00038700207,0.0003120714,0.0000027985398,0.000020244985,0.00006330418,0.000006502867,0.00019527329,0.9977543,0.000027588927,0.001189147,0.0000024577807],"about_ca_topic_score_codex":0.001895891,"about_ca_topic_score_gemma":0.002738714,"teacher_disagreement_score":0.002423978,"about_ca_system_score_codex":0.00070891675,"about_ca_system_score_gemma":0.0010150259,"threshold_uncertainty_score":0.0081089735},"labels":[],"label_agreement":null},{"id":"W2048842060","doi":"10.1038/gt.2011.53","title":"Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University Health Network; McMaster University; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institutes of Health; Terry Fox Foundation","keywords":"Immune system; Biology; Adenoviridae; Virology; Lentivirus; CD8; Splenocyte; Viral vector; Immunology; Immunotherapy; Spleen; Cytotoxic T cell; Antigen; Genetic enhancement; Virus; Recombinant DNA; In vitro; Viral disease","score_opus":0.030110039349117962,"score_gpt":0.24207809893662605,"score_spread":0.21196805958750808,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048842060","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969217,0.0002916669,0.0014600503,0.00009959626,0.000081438484,0.00006550684,0.0002611074,0.00006139349,0.00075750716],"genre_scores_gemma":[0.99614966,0.00029556706,0.0014286666,0.000057655674,0.000027443297,0.00008423122,0.00017041109,0.000022035372,0.0017644202],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99954045,0.00008101706,0.000043236054,0.00008757125,0.000091569666,0.00015624834],"domain_scores_gemma":[0.99964094,0.000119873286,0.00006900011,0.00005589249,0.000023738543,0.00009055702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045039266,0.0006793445,0.0005416726,0.0005446964,0.00029869768,0.0005281201,0.00032633686,0.00058291527,0.001024564],"category_scores_gemma":[0.00025547465,0.00027758916,0.000346724,0.0002924008,0.0006147417,0.00050125667,0.0002610188,0.0019978648,0.00024710162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00089551305,0.00029912757,0.0001440689,0.000029341645,0.0000062611475,0.00007300277,0.00004325968,0.00022129604,0.9970697,0.00044229272,0.000047199937,0.0007289139],"study_design_scores_gemma":[0.0001072017,0.0009538013,0.00076719397,0.000004138845,0.000026585169,0.00014225814,0.000036835438,0.0022342422,0.9949812,0.00012292646,0.00061510847,0.000008409925],"about_ca_topic_score_codex":0.0009033228,"about_ca_topic_score_gemma":0.00094255403,"teacher_disagreement_score":0.001024564,"about_ca_system_score_codex":0.0006695837,"about_ca_system_score_gemma":0.0005161094,"threshold_uncertainty_score":0.004858196},"labels":[],"label_agreement":null},{"id":"W2049023031","doi":"10.1038/sj.gt.3302479","title":"siRNA targeting the Leader sequence of SARS-CoV inhibits virus replication","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Genome Institute of Singapore; Tsinghua University; Harvard University","keywords":"Biology; Vero cell; Transfection; Gene silencing; Small interfering RNA; Coronavirus; Virology; Gene; Viral replication; Molecular biology; Reporter gene; RNA interference; Virus; Gene expression; RNA; Genetics; Coronavirus disease 2019 (COVID-19); Medicine","score_opus":0.1286294196693389,"score_gpt":0.39809590196463307,"score_spread":0.26946648229529413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049023031","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97618675,0.0055588614,0.0066654948,0.00045199748,0.00029784578,0.00010829871,0.00035550454,0.00037260095,0.010002735],"genre_scores_gemma":[0.9859175,0.002085837,0.0031790948,0.00017980942,0.00006276657,0.00009795667,0.0007432714,0.00005160123,0.0076821004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997869,0.00003677687,0.000019873909,0.000027251961,0.00005431844,0.00007485086],"domain_scores_gemma":[0.99984086,0.00006523185,0.000019679544,0.000018880673,0.000024098112,0.00003129924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027832083,0.00047869957,0.0006035264,0.00037263165,0.00033758138,0.00046206085,0.0002512814,0.0005028577,0.001934123],"category_scores_gemma":[0.00026480175,0.00018165454,0.0003380266,0.00013603257,0.00029811388,0.00024131309,0.00017902232,0.0006916651,0.000892918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020905717,0.00008855669,0.00009850208,0.000058272017,0.000009380441,0.000039850813,0.000021919945,0.00011149482,0.9929067,0.0002781827,0.00046763197,0.0057105604],"study_design_scores_gemma":[0.00009083623,0.0008246671,0.0014813081,0.000009287977,0.000024493444,0.00017798443,0.000023980192,0.0015940112,0.9911724,0.00010233416,0.0044921543,0.000006635451],"about_ca_topic_score_codex":0.000828357,"about_ca_topic_score_gemma":0.0015594147,"teacher_disagreement_score":0.001934123,"about_ca_system_score_codex":0.00047342497,"about_ca_system_score_gemma":0.00058008614,"threshold_uncertainty_score":0.006470263},"labels":[],"label_agreement":null},{"id":"W2049066646","doi":"10.1038/gt.2012.93","title":"Expression of HSV-1 receptors in EBV-associated lymphoproliferative disease determines susceptibility to oncolytic HSV","year":2012,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; Pelotonia; Ohio State University","keywords":"Oncolytic virus; Biology; Herpes simplex virus; Virus; Virology; Virotherapy; Herpesviridae; Viral replication; Cancer research; Immunology; Interferon; Viral disease","score_opus":0.03238748482780566,"score_gpt":0.3227070060446015,"score_spread":0.29031952121679583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049066646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99913174,0.00016574423,0.0001545354,0.00001456433,0.0000033770057,0.0000033480296,0.000047519727,0.0000074409313,0.00047187487],"genre_scores_gemma":[0.99948967,0.0000790852,0.00007633263,0.00000708366,0.000002588523,0.0000028758527,0.000052161027,0.0000062003005,0.00028400475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975985,0.000063773405,0.000023576637,0.000038134516,0.000031453943,0.00008319444],"domain_scores_gemma":[0.9995957,0.0001731226,0.0000772158,0.000047131798,0.000031284733,0.000075489705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016923218,0.00015686534,0.00016915928,0.00065693795,0.00021021275,0.00055021263,0.00018605361,0.00035497636,0.0032139276],"category_scores_gemma":[0.0006331755,0.00022089746,0.00017322623,0.00023432767,0.00032655656,0.00043679093,0.0003046775,0.0005851076,0.000583779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007818127,0.000072642106,0.009007963,0.000015993826,0.0000089573605,0.00028714127,0.00012330987,0.00006298664,0.9877396,0.00032107308,0.000044569377,0.0015339284],"study_design_scores_gemma":[0.00007240985,0.0011675681,0.22115327,0.000025322677,0.000092504335,0.008206013,0.000987789,0.0019156171,0.7624368,0.0011050493,0.002803365,0.000034213717],"about_ca_topic_score_codex":0.00024344515,"about_ca_topic_score_gemma":0.00018709734,"teacher_disagreement_score":0.0032139276,"about_ca_system_score_codex":0.00021281917,"about_ca_system_score_gemma":0.000105972744,"threshold_uncertainty_score":0.010751724},"labels":[],"label_agreement":null},{"id":"W2052107899","doi":"10.1038/gt.2011.210","title":"Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes","year":2012,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; McMaster University; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell; Human cell; Computational biology; Cell biology; Cell culture; Genetics","score_opus":0.01192696317910114,"score_gpt":0.25134958381698236,"score_spread":0.23942262063788122,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052107899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8761134,0.0006098134,0.11519612,0.00029271055,0.00012569001,0.0003098913,0.0023718614,0.0006715664,0.0043089315],"genre_scores_gemma":[0.94908035,0.000582482,0.037237205,0.00007056981,0.000019897367,0.00019563916,0.00199001,0.00021056343,0.010613377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997547,0.000044477118,0.00003253407,0.00005064094,0.000069943104,0.00004765922],"domain_scores_gemma":[0.9997012,0.00007954001,0.00008585542,0.00006138982,0.0000306381,0.00004135227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035763776,0.00049878925,0.00029039223,0.000222931,0.0002361259,0.00040157253,0.00032037095,0.00046187456,0.0015461132],"category_scores_gemma":[0.00030361212,0.00020693938,0.0003267948,0.0002554208,0.00039384677,0.000361125,0.00035867505,0.0009076495,0.00096685375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009119051,0.000016962289,0.000058211954,0.000025158284,0.0000028792902,0.000053596534,0.000024930408,0.00021641135,0.9971614,0.0008022872,0.00007284798,0.0014742548],"study_design_scores_gemma":[0.000007657535,0.000026316993,0.00016286228,0.0000018977386,0.0000054866823,0.00011376571,0.000005633597,0.0004250887,0.9969292,0.000051883417,0.00226754,0.0000027014005],"about_ca_topic_score_codex":0.00040936997,"about_ca_topic_score_gemma":0.0004549215,"teacher_disagreement_score":0.0015461132,"about_ca_system_score_codex":0.0005341015,"about_ca_system_score_gemma":0.0003923285,"threshold_uncertainty_score":0.0051722527},"labels":[],"label_agreement":null},{"id":"W2053377820","doi":"10.1038/sj.gt.3302081","title":"Widespread distribution of β-hexosaminidase activity in the brain of a Sandhoff mouse model after coinjection of adenoviral vector and mannitol","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Sandhoff disease; Viral vector; Biology; Genetic enhancement; Transduction (biophysics); Vector (molecular biology); Gangliosidosis; Molecular biology; Biochemistry; Enzyme; Recombinant DNA; Gene","score_opus":0.025986887192140175,"score_gpt":0.2992854785033272,"score_spread":0.27329859131118706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053377820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939208,0.0010788488,0.002656849,0.00015573109,0.000097822754,0.000036328223,0.00035086164,0.00016229542,0.0015404372],"genre_scores_gemma":[0.9922299,0.0010468971,0.0018306811,0.00006055501,0.000032205116,0.0000628237,0.00042864913,0.000048904527,0.0042594885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997476,0.000021253596,0.000023702098,0.00007891204,0.000048417987,0.00008017705],"domain_scores_gemma":[0.99964476,0.000049530943,0.000110606576,0.000037740923,0.0000318908,0.00012543937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026178843,0.0011309104,0.000583415,0.0016109186,0.00047828312,0.00059867935,0.0004201905,0.0007601351,0.001699066],"category_scores_gemma":[0.00019084445,0.00040989302,0.00046375243,0.00042298847,0.0010805004,0.0008527909,0.0004682977,0.0014749925,0.0004365087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066743116,0.000113729795,0.00019816242,0.000042022395,0.00002794278,0.00084298017,0.000055668348,0.00007826305,0.99668,0.0003109204,0.000071323026,0.00091159315],"study_design_scores_gemma":[0.000078732446,0.0009725605,0.0053638,0.00001601861,0.000119969096,0.003654708,0.00014596165,0.0012162207,0.9871083,0.00037262557,0.0009261829,0.000024830582],"about_ca_topic_score_codex":0.0016228303,"about_ca_topic_score_gemma":0.0013260399,"teacher_disagreement_score":0.001699066,"about_ca_system_score_codex":0.0004337973,"about_ca_system_score_gemma":0.00045720194,"threshold_uncertainty_score":0.005683899},"labels":[],"label_agreement":null},{"id":"W2055283290","doi":"10.1038/gt.2012.50","title":"SERCA2a gene transfer prevents intimal proliferation in an organ culture of human internal mammary artery","year":2012,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Coronary Interventions and Diagnostics","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; Fondation Leducq; American Heart Association","keywords":"Restenosis; Vascular smooth muscle; Medicine; Cardiology; Genetic enhancement; Intimal hyperplasia; Angioplasty; Neointimal hyperplasia; Internal medicine; Stent; Chemistry; Gene; Smooth muscle","score_opus":0.029109723991923922,"score_gpt":0.31343039421293944,"score_spread":0.28432067022101554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055283290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99166673,0.0014414765,0.0030714055,0.00015845486,0.00013039114,0.000042688236,0.00024373565,0.0000792772,0.003165868],"genre_scores_gemma":[0.98944384,0.0010622204,0.0027365806,0.00008772507,0.0000627419,0.000058237885,0.00049260375,0.000034720288,0.006021413],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99962306,0.00010678157,0.000030472473,0.00006650616,0.0000691734,0.000104011066],"domain_scores_gemma":[0.99956506,0.00019869984,0.00004182999,0.000101588295,0.00002765553,0.00006513449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047517192,0.00037892317,0.00036509475,0.00046143055,0.0003317192,0.00043339076,0.00036739442,0.00042324455,0.0018292537],"category_scores_gemma":[0.00031186003,0.00032346486,0.0004579657,0.00026163447,0.00034524463,0.0002785733,0.000236952,0.001091724,0.0005605272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004171968,0.00012629836,0.00008283742,0.000029215542,0.000006112596,0.00012924019,0.000059046288,0.00007748006,0.99803025,0.00017817262,0.000053586326,0.0008105462],"study_design_scores_gemma":[0.000042414114,0.000600026,0.0012446007,0.0000046298387,0.000023543134,0.00013219172,0.00004782615,0.0011693134,0.9954358,0.000042822256,0.0012542754,0.0000027429053],"about_ca_topic_score_codex":0.0011803843,"about_ca_topic_score_gemma":0.001540741,"teacher_disagreement_score":0.0018292537,"about_ca_system_score_codex":0.00026729773,"about_ca_system_score_gemma":0.00033600375,"threshold_uncertainty_score":0.0061194897},"labels":[],"label_agreement":null},{"id":"W2056459029","doi":"10.1038/gt.2011.141","title":"The oncolytic adenovirus AdΔΔ enhances selective cancer cell killing in combination with DNA-damaging drugs in pancreatic cancer models","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Home Office; Cancer Research UK; Public Health Agency of Canada","keywords":"Gemcitabine; Irinotecan; Pancreatic cancer; Oncolytic virus; Oncolytic adenovirus; Cancer research; Cisplatin; Genetic enhancement; Biology; Cytotoxic T cell; Cancer cell; Combination therapy; Cancer; Adenoviridae; Apoptosis; Pharmacology; Chemotherapy; In vitro; Gene; Colorectal cancer","score_opus":0.02466232265738422,"score_gpt":0.2930919940245822,"score_spread":0.268429671367198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056459029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942847,0.001295257,0.002752147,0.0001230403,0.000049937054,0.0000349513,0.00019329913,0.00008216364,0.0011845825],"genre_scores_gemma":[0.9939289,0.00096186204,0.002561113,0.000027296597,0.000011878464,0.000029857614,0.00019556421,0.000028255115,0.0022552782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997025,0.0000630419,0.00003312969,0.000056499288,0.00007890186,0.000065898574],"domain_scores_gemma":[0.9998037,0.000055591747,0.00003354513,0.00004120474,0.00001715577,0.000048791444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037475114,0.0005681219,0.0006115845,0.00069747685,0.0002293363,0.0004998504,0.0003511822,0.0003594427,0.0008232932],"category_scores_gemma":[0.0001871448,0.00029788178,0.00037813972,0.00046024995,0.00040880972,0.0004042716,0.00023616171,0.0009568294,0.00018617623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004482383,0.00013741216,0.00019491187,0.000047911293,0.000015597923,0.00005035883,0.000025378606,0.0002942509,0.99602735,0.0003106765,0.00006740614,0.002380584],"study_design_scores_gemma":[0.000028204737,0.00037899293,0.0005257926,0.000002994533,0.000023249973,0.000121576384,0.000010457292,0.00076678983,0.9972926,0.000042932134,0.00080355327,0.0000028416093],"about_ca_topic_score_codex":0.0014129982,"about_ca_topic_score_gemma":0.0016694751,"teacher_disagreement_score":0.0014129982,"about_ca_system_score_codex":0.00058877177,"about_ca_system_score_gemma":0.0005567911,"threshold_uncertainty_score":0.004271865},"labels":[],"label_agreement":null},{"id":"W2057587429","doi":"10.1038/gt.2012.68","title":"Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin–paclitaxel doublet chemotherapy","year":2012,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"National Cancer Institute; Oncolytics Biotech; Cancer Research UK","keywords":"Oncolytic virus; Paclitaxel; Cisplatin; Taxane; Chemotherapy; Cancer research; Head and neck cancer; Combination therapy; Cytotoxicity; Combination chemotherapy; Oncology; Medicine; Cancer; Virology; Pharmacology; Internal medicine; Biology; In vitro; Breast cancer","score_opus":0.023976625821498707,"score_gpt":0.3020503082894053,"score_spread":0.2780736824679066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057587429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.985987,0.006167721,0.0019095861,0.00022999992,0.00024900437,0.00019177045,0.00019575057,0.00014389445,0.0049253455],"genre_scores_gemma":[0.99627376,0.0014279523,0.0007392966,0.0000259568,0.000039263556,0.000052338855,0.00009884941,0.000016953189,0.0013256541],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996673,0.00011418081,0.0000247493,0.00004450861,0.00006114795,0.000088131936],"domain_scores_gemma":[0.9998197,0.000059701553,0.000020161719,0.00003823221,0.000015930764,0.00004626009],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033893273,0.000553602,0.001083276,0.0007659277,0.00036047612,0.00060983247,0.0005766007,0.00048635734,0.0018422131],"category_scores_gemma":[0.00041048505,0.00028716712,0.00055320375,0.0006232261,0.00037877652,0.00041905226,0.00037313395,0.0009267415,0.0003971665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018811792,0.0034778775,0.0018926554,0.0005131548,0.00039862256,0.0008938421,0.00040144104,0.008223901,0.87294954,0.0022834465,0.002609768,0.08754388],"study_design_scores_gemma":[0.0015469976,0.018938126,0.005053909,0.00005498199,0.00045314225,0.0013177173,0.00013472445,0.00626107,0.95536053,0.00030810453,0.0105180275,0.000052709212],"about_ca_topic_score_codex":0.0017572097,"about_ca_topic_score_gemma":0.0029330924,"teacher_disagreement_score":0.0018422131,"about_ca_system_score_codex":0.00066362653,"about_ca_system_score_gemma":0.000908096,"threshold_uncertainty_score":0.0061627626},"labels":[],"label_agreement":null},{"id":"W2058476279","doi":"10.1038/sj.gt.3302733","title":"Anatomically discrete functional effects of adenoviral clostridial light chain gene-based synaptic inhibition in the midbrain","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; York University; University of Michigan","keywords":"Midbrain; Neuroscience; Startle response; Biology; Synaptic vesicle; Cell biology; Central nervous system; Biochemistry; Vesicle","score_opus":0.008075512054310747,"score_gpt":0.21612713983763995,"score_spread":0.2080516277833292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058476279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915769,0.0013243125,0.0024428929,0.0002037906,0.000058479316,0.000019311006,0.00021784096,0.000077146484,0.004079263],"genre_scores_gemma":[0.99470043,0.00046841154,0.001313566,0.000052052175,0.0000050413446,0.000019361569,0.00010650712,0.00002780212,0.0033067847],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986744,0.000012242003,0.0000060686407,0.000024590492,0.0000353939,0.000054239314],"domain_scores_gemma":[0.9998977,0.000026370271,0.000018951741,0.000009817361,0.000010431828,0.000036640347],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001484756,0.00040895707,0.0002727297,0.00034720163,0.00034435894,0.00055598235,0.00041427958,0.00048364315,0.001608863],"category_scores_gemma":[0.0001527306,0.00018080212,0.0002557181,0.00012357415,0.0006966753,0.00039371892,0.00030214927,0.0010968007,0.0002453171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023685239,0.000031738102,0.000050456827,0.000021148344,0.000004359632,0.00006377118,0.00001618478,0.00008484327,0.9974794,0.0007713253,0.00003592456,0.0012039689],"study_design_scores_gemma":[0.000059149716,0.00031904818,0.0024826487,0.000009514569,0.000019515404,0.00024447253,0.00008635914,0.0011145624,0.9944694,0.0003055828,0.00088327867,0.000006427812],"about_ca_topic_score_codex":0.0034801913,"about_ca_topic_score_gemma":0.0056551686,"teacher_disagreement_score":0.0034801913,"about_ca_system_score_codex":0.0009123303,"about_ca_system_score_gemma":0.00057617365,"threshold_uncertainty_score":0.006919861},"labels":[],"label_agreement":null},{"id":"W2058963225","doi":"10.1038/sj.gt.3302797","title":"HER-2/neu-gene engineered dendritic cell vaccine stimulates stronger HER-2/neu-specific immune responses compared to DNA vaccination","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Cancer Agency","keywords":"DNA vaccination; Biology; HER2/neu; Immune system; Dendritic cell; Vaccination; Immunology; Antigen; Genetic enhancement; Naked DNA; Cancer research; Transgene; Cancer; Breast cancer; Gene; Immunization; Genetics","score_opus":0.013660441332778484,"score_gpt":0.236089697317357,"score_spread":0.2224292559845785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058963225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936062,0.00086800795,0.002940865,0.00012786851,0.00020607322,0.000072254596,0.00013122731,0.00008803802,0.0019594429],"genre_scores_gemma":[0.9956495,0.00039336996,0.0018097786,0.00013769999,0.000059347512,0.000043323565,0.00014101803,0.000029046427,0.0017369525],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995683,0.00008321921,0.000025750081,0.00008114938,0.00008501609,0.0001566826],"domain_scores_gemma":[0.99972767,0.00011355438,0.00003830701,0.00003241192,0.000031462558,0.000056576308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037357473,0.0006407199,0.0008225486,0.00043269084,0.00016857173,0.000517599,0.00022469321,0.00057458214,0.002178358],"category_scores_gemma":[0.00035683403,0.00021061058,0.0003459791,0.00025526306,0.00032970292,0.00045519957,0.00037221503,0.001392945,0.00052270415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004966963,0.00022414699,0.00010362263,0.000059540263,0.000011441775,0.000032405023,0.000016802225,0.00017230437,0.99623185,0.00013470287,0.00006971372,0.00244684],"study_design_scores_gemma":[0.00012833074,0.0012137672,0.0010135323,0.000008371583,0.00003952087,0.00016753629,0.000025165758,0.001059409,0.99504435,0.00011322524,0.0011811372,0.000005614758],"about_ca_topic_score_codex":0.0003272054,"about_ca_topic_score_gemma":0.0005267961,"teacher_disagreement_score":0.002178358,"about_ca_system_score_codex":0.00040814097,"about_ca_system_score_gemma":0.00040099834,"threshold_uncertainty_score":0.007287383},"labels":[],"label_agreement":null},{"id":"W2059570913","doi":"10.1038/sj.gt.3301716","title":"Inducing neutrophil recruitment in the liver of ICAM-1-deficient mice using polyethyleneimine grafted with Pluronic P123 as an organ-specific carrier for transgenic ICAM-1","year":2002,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Supratek Pharma (Canada); Institut National de la Recherche Scientifique","funders":"National Science Foundation","keywords":"Biology; Transgene; ICAM-1; Effector; Immune system; Molecular biology; Chemokine; Cell adhesion molecule; Gene delivery; Intercellular Adhesion Molecule-1; Transfection; Cell biology; Immunology; Gene; Biochemistry","score_opus":0.17163979547697394,"score_gpt":0.34105174860896076,"score_spread":0.16941195313198681,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059570913","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99368614,0.00072820875,0.003810901,0.00025109982,0.000064715714,0.00007453871,0.00024352307,0.00016405735,0.0009768627],"genre_scores_gemma":[0.9913857,0.00065121555,0.0030313416,0.000111709975,0.000025111945,0.00009223464,0.0002815033,0.000058902453,0.0043623666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997507,0.000043536715,0.000023554892,0.000050658557,0.000051186194,0.00008040487],"domain_scores_gemma":[0.9996606,0.00005574464,0.000111790534,0.000039886003,0.000018897696,0.00011299131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030533146,0.000786089,0.00048592224,0.0004980635,0.00022706739,0.00036689077,0.00030496548,0.00067490345,0.0012299669],"category_scores_gemma":[0.00022948044,0.000349964,0.0003960304,0.00016342793,0.0004966527,0.0004656947,0.00025551362,0.0012820838,0.0003991701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037053035,0.00007358268,0.000059969556,0.000038849525,0.0000039815086,0.000110939145,0.0000225777,0.00008766807,0.9982749,0.00019164853,0.00003677547,0.0007285277],"study_design_scores_gemma":[0.00013641057,0.000996545,0.0015184798,0.000010849199,0.000031692896,0.00040798495,0.000037626738,0.0011498752,0.99459213,0.00013069251,0.000977059,0.0000106627485],"about_ca_topic_score_codex":0.0004507807,"about_ca_topic_score_gemma":0.00076762843,"teacher_disagreement_score":0.0012299669,"about_ca_system_score_codex":0.0003599447,"about_ca_system_score_gemma":0.0002942583,"threshold_uncertainty_score":0.0041146874},"labels":[],"label_agreement":null},{"id":"W2059955786","doi":"10.1038/sj.gt.3302682","title":"RNAi therapeutics: Can siRNAs conquer SARS?","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Small interfering RNA; Biology; Virology; RNA interference; Intensive care medicine; Medicine; RNA; Gene; Genetics","score_opus":0.02501780989997436,"score_gpt":0.27422218121958647,"score_spread":0.2492043713196121,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059955786","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016114207,0.5091198,0.04992076,0.36798048,0.011496226,0.00015870901,0.00040277507,0.0008607786,0.04394616],"genre_scores_gemma":[0.22812901,0.5701806,0.027230589,0.10019693,0.016564772,0.0005140676,0.00055530824,0.00039520132,0.05623357],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99842334,0.0006144525,0.00011042045,0.00017185816,0.00045021754,0.00022963173],"domain_scores_gemma":[0.99599445,0.0023788596,0.00034737916,0.00029630525,0.00068399194,0.0002989874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0082237795,0.0014201833,0.0026814523,0.0008661576,0.0009396762,0.003170726,0.0011312417,0.004208704,0.010064481],"category_scores_gemma":[0.0052375994,0.00043517258,0.0006857056,0.0005885928,0.0049533085,0.009283696,0.0016706494,0.008769487,0.0048286538],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018877069,0.00051086606,0.00139383,0.0031152233,0.00033980038,0.00080481503,0.00053417234,0.0014273179,0.050711725,0.27273864,0.1571377,0.50939816],"study_design_scores_gemma":[0.0004796955,0.0019074591,0.0013585145,0.00110191,0.00028952316,0.0025870684,0.00097475806,0.002014034,0.02754296,0.3018917,0.6597032,0.00014914807],"about_ca_topic_score_codex":0.00042808766,"about_ca_topic_score_gemma":0.0012280716,"teacher_disagreement_score":0.010064481,"about_ca_system_score_codex":0.0013172249,"about_ca_system_score_gemma":0.002017631,"threshold_uncertainty_score":0.04349208},"labels":[],"label_agreement":null},{"id":"W2060882276","doi":"10.1038/gt.2009.111","title":"Neuroprotection using gene therapy to induce vascular endothelial growth factor-A expression","year":2009,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; A. Alfred Taubman Medical Research Institute","keywords":"Neuroprotection; Vascular endothelial growth factor; Regeneration (biology); Biology; Transcription factor; Neurite; Neurotrophic factors; Axon; Genetic enhancement; Neurodegeneration; Cell biology; Vascular endothelial growth factor A; Myogenesis; Nerve growth factor; Cancer research; Medicine; Myocyte; Neuroscience; Pathology; Gene; VEGF receptors; Receptor; Genetics","score_opus":0.022866718610446906,"score_gpt":0.2513229148518515,"score_spread":0.2284561962414046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060882276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92586803,0.015940733,0.04250898,0.0018979657,0.0009819545,0.00031941177,0.0006901801,0.00088279083,0.010909806],"genre_scores_gemma":[0.97050774,0.0073930365,0.014350458,0.00026555377,0.00009210356,0.000171248,0.0003118005,0.0000638119,0.006844148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999877,0.000021696895,0.000009291739,0.00003147434,0.000028823788,0.00003175304],"domain_scores_gemma":[0.9999268,0.000018589377,0.00001946343,0.000009407727,0.000010117042,0.000015667982],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024188135,0.0006220829,0.00042417803,0.0006743065,0.00029952836,0.00044884972,0.00034643323,0.00069662393,0.0012998224],"category_scores_gemma":[0.00015031149,0.00017550225,0.0004411097,0.00041533617,0.0005303144,0.0004374282,0.00018717673,0.0012945468,0.00033972954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003078215,0.00017742839,0.00012403153,0.00010002187,0.00003171595,0.0001832174,0.000029241462,0.00031046808,0.9876368,0.0019342151,0.00037729574,0.008787796],"study_design_scores_gemma":[0.00008774142,0.00073841197,0.00052256393,0.000011373717,0.000054617118,0.00034292255,0.00002111318,0.0008552889,0.99170285,0.00046995044,0.0051824716,0.000010723307],"about_ca_topic_score_codex":0.0012599005,"about_ca_topic_score_gemma":0.0012404243,"teacher_disagreement_score":0.0012998224,"about_ca_system_score_codex":0.0005371059,"about_ca_system_score_gemma":0.00058054633,"threshold_uncertainty_score":0.0043483377},"labels":[],"label_agreement":null},{"id":"W2066890949","doi":"10.1038/sj.gt.3302319","title":"Reovirus as an experimental therapeutic for brain and leptomeningeal metastases from breast cancer","year":2004,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Calgary; Alberta Cancer Foundation","funders":"Canadian Institutes of Health Research; National Cancer Institute; Alberta Heritage Foundation for Medical Research; Health Research Board","keywords":"Breast cancer; In vivo; Oncolytic virus; Medicine; Cancer research; Metastasis; Cancer; Pathology; Immunology; Biology; Internal medicine","score_opus":0.031232006564063063,"score_gpt":0.3581118640713567,"score_spread":0.32687985750729365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066890949","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94925046,0.025912963,0.008959517,0.0012118267,0.0010086754,0.0005067143,0.0007602317,0.0004216557,0.011967968],"genre_scores_gemma":[0.9806074,0.008524832,0.0042605344,0.0001343897,0.00015188969,0.00024777572,0.00048836804,0.00009943583,0.0054854034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99965,0.00011773946,0.0000175615,0.000050021805,0.000051429794,0.0001132488],"domain_scores_gemma":[0.99977905,0.00010282926,0.000026894828,0.000048186743,0.000010743828,0.000032318887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006184304,0.0006697078,0.00059000176,0.00094626483,0.00051463005,0.00061533693,0.0007933983,0.0010471606,0.0020733865],"category_scores_gemma":[0.0004248334,0.00026526494,0.0005378815,0.00044857507,0.00093367224,0.00077363884,0.00029113734,0.0014816716,0.00041895578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0065310365,0.0015089662,0.00026532024,0.00043725682,0.00008897944,0.00070655975,0.00016119042,0.00086753804,0.96388817,0.006993591,0.0007577894,0.017793545],"study_design_scores_gemma":[0.00075369276,0.0071176733,0.00074183306,0.000051336025,0.00015783939,0.0008788533,0.00008169925,0.00090086146,0.9784129,0.0008041088,0.010078346,0.000020914298],"about_ca_topic_score_codex":0.0020126377,"about_ca_topic_score_gemma":0.0017056982,"teacher_disagreement_score":0.0020733865,"about_ca_system_score_codex":0.0007226043,"about_ca_system_score_gemma":0.0006424381,"threshold_uncertainty_score":0.006936133},"labels":[],"label_agreement":null},{"id":"W2067074806","doi":"10.1038/gt.2012.43","title":"Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial","year":2012,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":399,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Cégep de Chicoutimi; Université du Québec à Chicoutimi","funders":"Canadian Institutes of Health Research; Health Canada; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"Hypertriglyceridemia; Lipoprotein lipase; Pancreatitis; Medicine; Internal medicine; Gastroenterology; Genetic enhancement; Acute pancreatitis; Lipoprotein; Endocrinology; Triglyceride; Biology; Cholesterol; Adipose tissue","score_opus":0.07772679673581326,"score_gpt":0.3550713739956776,"score_spread":0.2773445772598644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067074806","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99110186,0.0047851237,0.0010198294,0.00032867276,0.00028964994,0.0006206375,0.00047401013,0.00007657895,0.0013035311],"genre_scores_gemma":[0.9915888,0.0024627608,0.00070375105,0.00044493857,0.00044541387,0.0011044625,0.00078027474,0.000032092972,0.0024375822],"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","domain_scores_codex":[0.9987526,0.0005087503,0.0000951046,0.00023711467,0.00016578456,0.00024065813],"domain_scores_gemma":[0.9989489,0.00033226502,0.00024065402,0.00016046445,0.000074886324,0.00024283078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023978758,0.0017076316,0.00332585,0.0006219634,0.000574491,0.0018358032,0.00090746366,0.0029407428,0.002754456],"category_scores_gemma":[0.0013563798,0.0005007369,0.0023662061,0.00052217505,0.0023848587,0.0023147815,0.00032724347,0.0036532795,0.0010621789],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.8976653,0.02714517,0.0012097522,0.00045105617,0.00088881823,0.000118479256,0.00010839335,0.00068425154,0.025721671,0.0002380608,0.00065758376,0.045111395],"study_design_scores_gemma":[0.47786146,0.50074965,0.00498219,0.00006910574,0.000981679,0.00014618055,0.000081855935,0.0011989925,0.011565271,0.00043234095,0.001861522,0.000069707945],"about_ca_topic_score_codex":0.00036083264,"about_ca_topic_score_gemma":0.0003079902,"teacher_disagreement_score":0.00332585,"about_ca_system_score_codex":0.00089819735,"about_ca_system_score_gemma":0.0006518821,"threshold_uncertainty_score":0.012681365},"labels":[],"label_agreement":null},{"id":"W2067174670","doi":"10.1038/gt.2010.149","title":"Improved antibiotic-free plasmid vector design by incorporation of transient expression enhancers","year":2010,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of General Medical Sciences; Concordia University of Edmonton; Leukemia and Lymphoma Society","keywords":"Biology; Transgene; Enhancer; Electroporation; Plasmid; Insertional mutagenesis; Molecular biology; Expression cassette; Expression vector; Genetic enhancement; Gene expression; Gene; Vector (molecular biology); Genetics; Recombinant DNA; Genome","score_opus":0.01026448756898997,"score_gpt":0.23001164231857313,"score_spread":0.21974715474958315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067174670","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.29456738,0.0024412894,0.6970221,0.00043525896,0.00025705455,0.0005428964,0.00054526347,0.0021019606,0.0020868306],"genre_scores_gemma":[0.44713283,0.0027191122,0.5395002,0.00020953061,0.000048338246,0.00053908787,0.0018422373,0.00074413355,0.0072646015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990963,0.00015306396,0.00015008368,0.00017732882,0.00032770724,0.000095577205],"domain_scores_gemma":[0.99938023,0.0001602902,0.00015002329,0.00008442407,0.00015156445,0.00007344873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009738894,0.00091226853,0.0009804486,0.00059490534,0.0003676293,0.0008416397,0.0009382819,0.0007748433,0.0011789118],"category_scores_gemma":[0.0009839869,0.00070934993,0.00060495955,0.0004981253,0.00045419746,0.00077375316,0.00045133475,0.0016160681,0.0008680646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008120408,0.00003489092,0.000047229656,0.00008149222,0.0000064056485,0.000035979876,0.000019717994,0.00020972159,0.9939282,0.00083991024,0.00007417375,0.004641082],"study_design_scores_gemma":[0.00001954876,0.00007870723,0.0001600518,0.0000045864776,0.000020377667,0.00014998985,0.0000047293065,0.0014820708,0.9944102,0.00010707531,0.0035502464,0.000012433214],"about_ca_topic_score_codex":0.0004326667,"about_ca_topic_score_gemma":0.0010130754,"teacher_disagreement_score":0.0011789118,"about_ca_system_score_codex":0.00057790085,"about_ca_system_score_gemma":0.00065756246,"threshold_uncertainty_score":0.005150497},"labels":[],"label_agreement":null},{"id":"W2071241105","doi":"10.1038/gt.2009.68","title":"PML has a predictive role in tumor cell permissiveness to interferon-sensitive oncolytic viruses","year":2009,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Oncolytic virus; Biology; Vesicular stomatitis virus; Promyelocytic leukemia protein; Virology; Herpes simplex virus; Interferon; Permissiveness; Virus; Viral replication; Cell culture; Acute promyelocytic leukemia; Retinoic acid; Genetics","score_opus":0.02401475307923431,"score_gpt":0.3023987386276803,"score_spread":0.278383985548446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071241105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.983991,0.0025675558,0.008792286,0.000144076,0.000027111746,0.000029797848,0.00044048717,0.00028693184,0.003720792],"genre_scores_gemma":[0.9977889,0.00035424004,0.0007935073,0.000010259633,0.0000067694245,0.000008381363,0.00016261547,0.000022006183,0.00085329567],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99967456,0.000074600095,0.00003122505,0.000072683,0.00009771867,0.000049173726],"domain_scores_gemma":[0.99903095,0.0004439893,0.00015209882,0.00018829906,0.00008226005,0.00010240338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007839776,0.00037822285,0.00030841157,0.0011669208,0.0005277565,0.0013544003,0.00041851573,0.00044052082,0.0017784855],"category_scores_gemma":[0.0017719176,0.00030299276,0.00024877692,0.0004661186,0.0008510379,0.0012488901,0.00043639244,0.0009117399,0.00056575134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014948259,0.00007651343,0.008547127,0.000041897765,0.000011899982,0.00026335896,0.0001697125,0.0005067435,0.97982854,0.0016918724,0.000070919225,0.007296554],"study_design_scores_gemma":[0.000008985352,0.00020803665,0.011602528,0.000005741529,0.00001744664,0.0005863432,0.00007001541,0.0015142314,0.9846207,0.0004994792,0.000858177,0.0000082071065],"about_ca_topic_score_codex":0.00082532957,"about_ca_topic_score_gemma":0.0004508316,"teacher_disagreement_score":0.0017784855,"about_ca_system_score_codex":0.0005500939,"about_ca_system_score_gemma":0.00031483482,"threshold_uncertainty_score":0.0059496164},"labels":[],"label_agreement":null},{"id":"W2072238337","doi":"10.1038/sj.gt.3302394","title":"Direct evidence for the absence of intercellular trafficking of VP22 fused to GFP or to the herpes simplex virus thymidine kinase","year":2004,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec; Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Thymidine kinase; Herpes simplex virus; Biology; Ganciclovir; Green fluorescent protein; Cell culture; Suicide gene; Transduction (biophysics); Bystander effect; Western blot; Intracellular; Virology; Molecular biology; Transfection; Virus; Cell biology; Genetic enhancement; Gene; Immunology; Biochemistry; Genetics","score_opus":0.08108547277799955,"score_gpt":0.3633732954227377,"score_spread":0.2822878226447382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072238337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9582115,0.0026287788,0.024966944,0.0003511261,0.00012925881,0.00003303232,0.00062881404,0.0002906593,0.012759853],"genre_scores_gemma":[0.9881356,0.0010172111,0.0051267385,0.00009615371,0.000016427322,0.00004683187,0.001090071,0.00011676282,0.004354128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998029,0.000023792778,0.000014290902,0.00004456996,0.00006760327,0.00004687134],"domain_scores_gemma":[0.9993311,0.00024496537,0.00008724186,0.00014046828,0.00009770001,0.00009857762],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026546256,0.0004767192,0.00029566267,0.00028472338,0.00045505687,0.0009279873,0.0003832357,0.0007662621,0.002006989],"category_scores_gemma":[0.00057778246,0.00020249152,0.00024622158,0.00027425142,0.00061493536,0.00062363106,0.00060363195,0.0010799257,0.0010229109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003896696,0.00000880919,0.00013076249,0.000028255863,0.0000040706236,0.00011229779,0.000021723008,0.00002341783,0.9980738,0.0008950284,0.00004262864,0.00062015257],"study_design_scores_gemma":[0.000010029565,0.00003962127,0.0020794875,0.000007011534,0.000017768192,0.0012967604,0.000057954545,0.0005077916,0.99275583,0.00030118122,0.0029223058,0.000004258173],"about_ca_topic_score_codex":0.0007570357,"about_ca_topic_score_gemma":0.00053297833,"teacher_disagreement_score":0.002006989,"about_ca_system_score_codex":0.00037608627,"about_ca_system_score_gemma":0.00047519204,"threshold_uncertainty_score":0.0067139864},"labels":[],"label_agreement":null},{"id":"W2077847265","doi":"10.1038/sj.gt.3302845","title":"Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"XIAP; Inhibitor of apoptosis; Biology; Cancer research; Apoptosis; Glioma; Programmed cell death; Caspase; Molecular biology; Biochemistry","score_opus":0.007045515253137752,"score_gpt":0.21696676773268053,"score_spread":0.20992125247954277,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077847265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923907,0.0014625064,0.0025551312,0.00019376141,0.00007346979,0.000041645686,0.00033890686,0.00022907923,0.002714819],"genre_scores_gemma":[0.9936935,0.00082625507,0.0012419289,0.00003546036,0.0000144507,0.000032813303,0.00040365543,0.000030645977,0.0037213303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997793,0.000028691064,0.000019743296,0.000035959416,0.000072377945,0.000063933825],"domain_scores_gemma":[0.99980825,0.00004790895,0.000054617503,0.000030707582,0.000011398685,0.00004714173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023043399,0.000540523,0.0003462952,0.0006121717,0.00023061619,0.00040060058,0.00030125244,0.0003258335,0.0012680389],"category_scores_gemma":[0.00013209891,0.00025119924,0.00028461858,0.00027486894,0.00038531335,0.0002662724,0.0001640498,0.0010637054,0.00032322132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011482234,0.000048364673,0.00010207875,0.000015564934,0.0000054807774,0.00003181673,0.000016160202,0.000099781835,0.99846774,0.00025387068,0.000055994267,0.0007882707],"study_design_scores_gemma":[0.000039961393,0.00038235972,0.0010849639,0.0000037169034,0.000015593598,0.00014049101,0.000022669949,0.0012964716,0.9956067,0.00007408406,0.0013295659,0.0000034172035],"about_ca_topic_score_codex":0.002026254,"about_ca_topic_score_gemma":0.0020969282,"teacher_disagreement_score":0.002026254,"about_ca_system_score_codex":0.00048778873,"about_ca_system_score_gemma":0.0003584734,"threshold_uncertainty_score":0.004242003},"labels":[],"label_agreement":null},{"id":"W2078901418","doi":"10.1038/sj.gt.3302486","title":"Combined CD4+ Th1 effect and lymphotactin transgene expression enhance CD8+ Tc1 tumor localization and therapy","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Transgene; CD8; Biology; Cytotoxic T cell; Adoptive cell transfer; Genetic enhancement; Ovalbumin; Cancer research; T cell; T-cell receptor; Immunotherapy; Molecular biology; Immunology; Cell therapy; Cell; Immune system; In vitro; Gene; Biochemistry","score_opus":0.007303783084616129,"score_gpt":0.23993815804561408,"score_spread":0.23263437496099795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078901418","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98189193,0.0025972745,0.009948308,0.00017819856,0.00008818886,0.00014382516,0.00025907595,0.00040088108,0.0044923574],"genre_scores_gemma":[0.99100846,0.0004781728,0.0045126793,0.000049010298,0.000037382553,0.00008841959,0.00011599747,0.00005487124,0.0036551554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995859,0.00006473492,0.000025456166,0.00008092707,0.00010021017,0.00014272869],"domain_scores_gemma":[0.99982435,0.00004829631,0.000037728776,0.000030374322,0.000017321841,0.000041951076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030474956,0.0007515695,0.0006989297,0.0008710233,0.0002634364,0.00058157207,0.0003457265,0.000613585,0.0028892101],"category_scores_gemma":[0.000165259,0.0002703036,0.0003787832,0.00034604705,0.00042024118,0.0005098087,0.00037893688,0.0012871724,0.0005850956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021682215,0.00009681491,0.00008188297,0.00003915595,0.0000075055277,0.00002291504,0.000013903075,0.00017188872,0.99669695,0.00024440495,0.000047777266,0.002359982],"study_design_scores_gemma":[0.000056146186,0.0003954028,0.00047014342,0.0000033654924,0.000025943651,0.00008930935,0.000009287851,0.00083123666,0.9966222,0.000055105025,0.0014384406,0.0000034394523],"about_ca_topic_score_codex":0.00083371083,"about_ca_topic_score_gemma":0.0016467017,"teacher_disagreement_score":0.0028892101,"about_ca_system_score_codex":0.00050075096,"about_ca_system_score_gemma":0.00041588195,"threshold_uncertainty_score":0.00966537},"labels":[],"label_agreement":null},{"id":"W2080214438","doi":"10.1038/gt.2010.172","title":"Overexpression of X-linked inhibitor of apoptosis protein protects against noise-induced hearing loss in mice","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Program of Shanghai Subject Chief Scientist; Ministry of Science and Technology of the People's Republic of China","keywords":"Spiral ganglion; Hearing loss; Cochlea; Noise-induced hearing loss; Apoptosis; Inner ear; Sound exposure; Hair cell; XIAP; Auditory brainstem response; Inhibitor of apoptosis; Biology; Internal medicine; Programmed cell death; Chemistry; Audiology; Medicine; Noise exposure; Anatomy; Biochemistry; Caspase","score_opus":0.08901560235797733,"score_gpt":0.28180459125163554,"score_spread":0.1927889888936582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080214438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99250233,0.0018768157,0.0036716699,0.00024911462,0.000088818626,0.00004520695,0.00032255845,0.00028929842,0.0009541328],"genre_scores_gemma":[0.98923314,0.0015762186,0.0032726484,0.00010291654,0.000043477856,0.00008545534,0.0005918415,0.00009082284,0.0050033713],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996772,0.0000498686,0.000040920455,0.00007523811,0.000069444395,0.00008738359],"domain_scores_gemma":[0.9994987,0.00006893439,0.00022181717,0.00005128053,0.00002878748,0.00013030026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042095847,0.0008754214,0.0006035848,0.0010585075,0.0002922896,0.0005589731,0.000582712,0.00081945286,0.0011658414],"category_scores_gemma":[0.00025989412,0.00036425132,0.00049817556,0.00034795664,0.0007077708,0.00045381556,0.00024914913,0.0012276004,0.0004251095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007548438,0.00016544187,0.00015235857,0.00003262659,0.000018947076,0.00009706302,0.000020414513,0.00012927779,0.997115,0.00016372149,0.00005541423,0.0012949724],"study_design_scores_gemma":[0.00024221072,0.0015842261,0.0022767766,0.000015733027,0.00008493911,0.00031906329,0.00005168224,0.0015064436,0.9923044,0.00014449097,0.0014553997,0.000014609739],"about_ca_topic_score_codex":0.00046665853,"about_ca_topic_score_gemma":0.00058606145,"teacher_disagreement_score":0.0011658414,"about_ca_system_score_codex":0.00034255296,"about_ca_system_score_gemma":0.00039061336,"threshold_uncertainty_score":0.0039001107},"labels":[],"label_agreement":null},{"id":"W2080273948","doi":"10.1038/gt.2009.29","title":"Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity","year":2009,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"U.S. Public Health Service; National Cancer Institute; Cancer Research UK; National Institutes of Health; Oncolytics Biotech; Richard M. Schulze Family Foundation; Mayo Foundation for Medical Education and Research","keywords":"Oncolytic virus; Virology; Biology; Immunity; Virus; Immunology; Immune system","score_opus":0.028671146884606837,"score_gpt":0.3150538259693597,"score_spread":0.2863826790847529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080273948","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9619793,0.0075442116,0.022291107,0.0006267893,0.00035326768,0.00018720048,0.00038256004,0.0003559192,0.006279578],"genre_scores_gemma":[0.98772603,0.001670551,0.0054783877,0.00012720055,0.000059999224,0.00007576696,0.0001901547,0.00006849114,0.0046033966],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997236,0.000030635398,0.000015496244,0.00006920748,0.000056301786,0.00010472766],"domain_scores_gemma":[0.99986875,0.000033741977,0.00003144408,0.000021273127,0.000016855605,0.000027884493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002859309,0.0005521396,0.00043765368,0.00031546157,0.00022861586,0.00091483945,0.00044513674,0.00093906175,0.0014985864],"category_scores_gemma":[0.0002483764,0.00031647432,0.00046474545,0.0001599188,0.0005085025,0.0008128568,0.00042701839,0.0013959191,0.000774455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038249348,0.000054210606,0.00008477042,0.000061462524,0.000013438402,0.00006761388,0.000032131557,0.00028169577,0.99417084,0.0015857556,0.00013730943,0.003128373],"study_design_scores_gemma":[0.000104683204,0.00034196858,0.00017741157,0.0000060544317,0.000027791324,0.00017351682,0.000023024399,0.0011449741,0.9942384,0.0003474075,0.0034082176,0.000006681785],"about_ca_topic_score_codex":0.0006973276,"about_ca_topic_score_gemma":0.0006989191,"teacher_disagreement_score":0.0014985864,"about_ca_system_score_codex":0.00069798686,"about_ca_system_score_gemma":0.00041075633,"threshold_uncertainty_score":0.005064249},"labels":[],"label_agreement":null},{"id":"W2080701229","doi":"10.1038/sj.gt.3301941","title":"Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Utrophin; Dystrophin; Duchenne muscular dystrophy; Muscular dystrophy; Biology; Minigene; Transgene; mdx mouse; Molecular biology; Genetic enhancement; Cell biology; Gene; Genetics; Messenger RNA; Alternative splicing","score_opus":0.008213302828905948,"score_gpt":0.21595609610511982,"score_spread":0.20774279327621387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080701229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933101,0.0015054112,0.0029404669,0.00016691032,0.000054384473,0.000027662143,0.00019325595,0.00011320071,0.0016885438],"genre_scores_gemma":[0.99396944,0.0006157732,0.0020381946,0.00003321008,0.000013899477,0.000026045867,0.00021632058,0.00004187579,0.0030452725],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99976796,0.000050744293,0.00003210267,0.000037102807,0.000044539083,0.00006760414],"domain_scores_gemma":[0.99980134,0.00005305763,0.00005016846,0.000031600805,0.000015818789,0.000048016063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003456616,0.00039108936,0.0003770724,0.00040690947,0.00028818988,0.0003205396,0.0002830186,0.0004368267,0.0012481475],"category_scores_gemma":[0.00026471997,0.00028023342,0.00024089056,0.00013978235,0.0005314689,0.0004154086,0.00029931767,0.0005334416,0.0002807003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001846043,0.000024113968,0.00010913957,0.00003513782,0.0000053545446,0.00007465205,0.000021686568,0.00008181507,0.9981962,0.00041762745,0.000044899203,0.0008047647],"study_design_scores_gemma":[0.00005485183,0.0003716988,0.002283408,0.000010915202,0.000036209993,0.0006473034,0.00004504507,0.0014538058,0.99213845,0.00013298364,0.002816953,0.00000837589],"about_ca_topic_score_codex":0.0008417106,"about_ca_topic_score_gemma":0.0015261568,"teacher_disagreement_score":0.0012481475,"about_ca_system_score_codex":0.00031959702,"about_ca_system_score_gemma":0.0002880089,"threshold_uncertainty_score":0.004175484},"labels":[],"label_agreement":null},{"id":"W2082319347","doi":"10.1038/gt.2015.25","title":"Gene delivery to the spinal cord using MRI-guided focused ultrasound","year":2015,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":93,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Toronto Rehabilitation Institute; Sunnybrook Hospital; Sunnybrook Health Science Centre","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research","keywords":"Spinal cord; Gene delivery; Microbubbles; Genetic enhancement; Magnetic resonance imaging; Green fluorescent protein; Viral vector; Biology; Medicine; Pathology; Neuroscience; Ultrasound; Gene; Radiology; Genetics","score_opus":0.0741115189746451,"score_gpt":0.2847105430707936,"score_spread":0.21059902409614847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082319347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81464964,0.03431455,0.13317072,0.0017939236,0.0004786306,0.0004525345,0.0004055756,0.0009785929,0.013755677],"genre_scores_gemma":[0.9306919,0.012640049,0.044607356,0.00044069032,0.00015509657,0.00023652629,0.00015418664,0.000087232,0.010986934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998536,0.000019776235,0.000007736307,0.000044635555,0.00004402068,0.000030213365],"domain_scores_gemma":[0.9999181,0.0000237859,0.000026542706,0.0000066456637,0.000012901854,0.000012010709],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024550708,0.0004587393,0.00036323586,0.00050024595,0.0002692742,0.00041647645,0.00047393425,0.00059732934,0.0010880993],"category_scores_gemma":[0.00033014925,0.00022059184,0.00031468927,0.00020991733,0.0004617337,0.0004504899,0.00032187754,0.00047782678,0.00036170642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009194854,0.000042795287,0.00007439845,0.00015710937,0.000010121706,0.00012001984,0.00006166237,0.0003814939,0.98950547,0.00040080125,0.00021804178,0.00893598],"study_design_scores_gemma":[0.000051698065,0.0009432501,0.0012917493,0.000035386554,0.00006207916,0.00067122106,0.000047454792,0.0024907643,0.98850363,0.00017091115,0.005710717,0.000021044807],"about_ca_topic_score_codex":0.0028327007,"about_ca_topic_score_gemma":0.0035657843,"teacher_disagreement_score":0.0028327007,"about_ca_system_score_codex":0.00038662305,"about_ca_system_score_gemma":0.00049697777,"threshold_uncertainty_score":0.00563246},"labels":[],"label_agreement":null},{"id":"W2082857033","doi":"10.1038/sj.gt.3302836","title":"Gene therapy of diabetes using a novel GLP-1/IgG1-Fc fusion construct normalizes glucose levels in db/db mice","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"","keywords":"Fusion protein; Incretin; Glucose homeostasis; Biology; Insulin; Glucagon-like peptide-1; Glucagon; Fusion gene; Peptide; Endocrinology; Internal medicine; Glucagon-like peptide 1 receptor; Cell biology; Receptor; Diabetes mellitus; Type 2 diabetes; Gene; Biochemistry; Insulin resistance; Recombinant DNA; Medicine","score_opus":0.03750412926097298,"score_gpt":0.2708164528455693,"score_spread":0.23331232358459633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082857033","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97502285,0.001510694,0.014869199,0.0012269206,0.00055663916,0.00011409632,0.0018406664,0.0012719645,0.0035869714],"genre_scores_gemma":[0.9693876,0.0018195248,0.014565954,0.00055275846,0.0001529335,0.0002738329,0.0018136823,0.00067086756,0.010762927],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992004,0.000099927835,0.00009001025,0.0002142349,0.00017153376,0.00022392863],"domain_scores_gemma":[0.9993019,0.000086731874,0.00020257206,0.000059583173,0.00004904119,0.00030016399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005912075,0.0013529815,0.0010894254,0.0016460975,0.00050179067,0.0010470384,0.00091434707,0.00117391,0.0025594232],"category_scores_gemma":[0.000280768,0.0004821419,0.0007976453,0.00063799915,0.0011479465,0.0006378505,0.00032402968,0.003874044,0.0005968514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000474253,0.00019131845,0.00007374731,0.00002767424,0.000011348434,0.00004335307,0.000017136523,0.00006177476,0.99796695,0.00022122075,0.00011199145,0.0007993531],"study_design_scores_gemma":[0.000075115146,0.000238649,0.00054236857,0.0000059608637,0.0000313637,0.000116322975,0.000025636147,0.00065995514,0.99715483,0.000056210112,0.0010867765,0.000006776365],"about_ca_topic_score_codex":0.0019895989,"about_ca_topic_score_gemma":0.0021388687,"teacher_disagreement_score":0.0025594232,"about_ca_system_score_codex":0.0009056074,"about_ca_system_score_gemma":0.0007336222,"threshold_uncertainty_score":0.008562148},"labels":[],"label_agreement":null},{"id":"W2084544749","doi":"10.1038/sj.gt.3301919","title":"A neovascularized organoid derived from retrovirally engineered bone marrow stroma leads to prolonged in vivo systemic delivery of erythropoietin in nonmyeloablated, immunocompetent mice","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University Health Centre; McGill University","funders":"","keywords":"Mesenchymal stem cell; Erythropoietin; Bone marrow; In vivo; Matrigel; Ex vivo; Medicine; Stromal cell; Progenitor cell; Stem cell; Pharmacology; Immunology; Pathology; Cancer research; Biology; Internal medicine; Angiogenesis; Cell biology","score_opus":0.014457358147826779,"score_gpt":0.24118151085437087,"score_spread":0.22672415270654409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084544749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99161094,0.0009338207,0.0054609613,0.000114841525,0.000060932634,0.0000636136,0.00039600875,0.00019761613,0.0011614303],"genre_scores_gemma":[0.99122775,0.0004730587,0.0035308104,0.000047004636,0.000020830867,0.00007507817,0.0004412871,0.000100723664,0.0040834984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99965084,0.000049497954,0.00002970666,0.0000910135,0.000084303785,0.00009475954],"domain_scores_gemma":[0.9994822,0.00012047342,0.00020020366,0.000049596994,0.000017368757,0.00013018024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046819614,0.00049586786,0.000493995,0.00067588635,0.00027658345,0.0005327175,0.0004843225,0.0006003667,0.0012542934],"category_scores_gemma":[0.00021770087,0.0003707584,0.0004297278,0.0002230507,0.00062361767,0.0004391349,0.00028813272,0.0011954176,0.0003872363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013446936,0.00004716332,0.000045487035,0.000013351489,0.000003974761,0.00006336099,0.00002530101,0.000078855526,0.9988925,0.000213158,0.000029354442,0.00045309466],"study_design_scores_gemma":[0.000042276228,0.0004262114,0.000898747,0.000005024519,0.000019221317,0.00028521617,0.00002096071,0.00088064524,0.9965753,0.0000521388,0.0007886382,0.000005503513],"about_ca_topic_score_codex":0.00063009537,"about_ca_topic_score_gemma":0.0010267871,"teacher_disagreement_score":0.0012542934,"about_ca_system_score_codex":0.00045157722,"about_ca_system_score_gemma":0.00029916508,"threshold_uncertainty_score":0.004196048},"labels":[],"label_agreement":null},{"id":"W2086420473","doi":"10.1038/gt.2010.26","title":"Meganucleases can restore the reading frame of a mutated dystrophin","year":2010,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Frameshift mutation; Dystrophin; Biology; Genetics; Nonsense mutation; Duchenne muscular dystrophy; Stop codon; Molecular biology; Utrophin; Open reading frame; Reading frame; Mutation; Insertion; Gene; Peptide sequence","score_opus":0.007258401173955907,"score_gpt":0.2361886224180967,"score_spread":0.2289302212441408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086420473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9376279,0.017439036,0.030452194,0.0011266018,0.0008366067,0.00024355027,0.00089892116,0.00058894866,0.010786201],"genre_scores_gemma":[0.96689636,0.008574023,0.0127134845,0.00024624102,0.00009185206,0.00016134164,0.0016299281,0.00017803507,0.009508747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997336,0.000068769215,0.000042275216,0.000042222677,0.00006610267,0.000046872698],"domain_scores_gemma":[0.99971503,0.00011251625,0.000074891606,0.000039044695,0.000020634294,0.000037931255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003981419,0.0007022434,0.0003555969,0.0004988577,0.00017743357,0.0004360454,0.00037537524,0.0006709785,0.0019284555],"category_scores_gemma":[0.00052488345,0.0003322563,0.00031521235,0.00026173328,0.00031497804,0.00027241991,0.00044718388,0.0010703696,0.00075704476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031217866,0.000051097206,0.00011974378,0.000105676634,0.000026991613,0.00016377089,0.000025114387,0.00011485376,0.9926012,0.0012294819,0.00023381994,0.005016106],"study_design_scores_gemma":[0.000075548814,0.00023530009,0.0011601304,0.000022906323,0.000050384806,0.00067982427,0.000014473756,0.00046559903,0.98732823,0.0003946545,0.009566026,0.0000069653443],"about_ca_topic_score_codex":0.00029985496,"about_ca_topic_score_gemma":0.00037140577,"teacher_disagreement_score":0.0019284555,"about_ca_system_score_codex":0.00029985237,"about_ca_system_score_gemma":0.00020587663,"threshold_uncertainty_score":0.0064513087},"labels":[],"label_agreement":null},{"id":"W2090736192","doi":"10.1038/sj.gt.3302944","title":"In vivo expression of GLP-1/IgG-Fc fusion protein enhances beta-cell mass and protects against streptozotocin-induced diabetes","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"","keywords":"Streptozotocin; Beta cell; Endocrinology; Glucagon-like peptide-1; Internal medicine; Islet; In vivo; Type 1 diabetes; Diabetes mellitus; Type 2 diabetes; Immunoglobulin G; Insulin; Glucose homeostasis; Medicine; Immunology; Biology; Insulin resistance; Antibody","score_opus":0.014900753737200354,"score_gpt":0.2529619815113299,"score_spread":0.23806122777412958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090736192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938883,0.00086271804,0.0027415096,0.00034691906,0.00013352165,0.00005022069,0.0004969436,0.00026155912,0.0012182965],"genre_scores_gemma":[0.992527,0.0005317137,0.0022461032,0.000116240386,0.000059449212,0.0000595191,0.00072263455,0.00009798883,0.0036393069],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99965465,0.000054556538,0.000026197738,0.00006098155,0.0000584736,0.00014510706],"domain_scores_gemma":[0.999496,0.00010182502,0.00012781954,0.000049499253,0.000025741567,0.00019903827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003974239,0.00088691,0.000787155,0.00077978283,0.0003561781,0.000672867,0.0006283629,0.0007189531,0.0016598555],"category_scores_gemma":[0.00021987937,0.00032837476,0.00059897586,0.00044850836,0.00083866715,0.0005029778,0.00026239312,0.002722528,0.000444262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001270974,0.00029835736,0.00009146,0.000030666833,0.000013770863,0.000050386665,0.000026706388,0.00011356922,0.99711215,0.00014638534,0.00007193917,0.0007736078],"study_design_scores_gemma":[0.00013405166,0.0008708974,0.000877466,0.0000053227745,0.000041067466,0.00008049212,0.000032348413,0.00078763254,0.99652785,0.00004862453,0.00058887136,0.000005322267],"about_ca_topic_score_codex":0.0016562918,"about_ca_topic_score_gemma":0.0017152872,"teacher_disagreement_score":0.0016598555,"about_ca_system_score_codex":0.00080275035,"about_ca_system_score_gemma":0.00066861126,"threshold_uncertainty_score":0.0058244467},"labels":[],"label_agreement":null},{"id":"W2090841339","doi":"10.1038/gt.2012.12","title":"Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma","year":2012,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital","funders":"National Cancer Institute; National Science Council","keywords":"Medulloblastoma; Neural stem cell; Brain tumor; Cancer research; Camptothecin; Suicide gene; Prodrug; Stem cell; Genetic enhancement; Medicine; Irinotecan; Pharmacology; Biology; Pathology; Internal medicine; Cancer","score_opus":0.028601577232606205,"score_gpt":0.25163275023635845,"score_spread":0.22303117300375225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090841339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98436767,0.0014699498,0.008845761,0.0003969107,0.00015528023,0.00020481105,0.0007021907,0.00037335305,0.0034841094],"genre_scores_gemma":[0.98540395,0.0011097011,0.0051233377,0.000047690835,0.000019852287,0.000118711825,0.0004115073,0.00004069461,0.0077245603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997558,0.00002719716,0.000022495562,0.00005824875,0.00007319972,0.00006308693],"domain_scores_gemma":[0.9998785,0.000019340649,0.000038492315,0.000017870432,0.0000119611395,0.000033873628],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030420205,0.0005851851,0.00047031953,0.00090342184,0.00027297085,0.0002966331,0.00050837285,0.00067701965,0.0014287777],"category_scores_gemma":[0.00012882272,0.00027920026,0.0003809631,0.00034410262,0.0007698092,0.0005116421,0.00017140183,0.0012953522,0.00035103477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004596581,0.00020566554,0.00012743531,0.000056059525,0.000011253115,0.00023028109,0.0000418631,0.00022879867,0.9953792,0.000944678,0.00013808745,0.002176871],"study_design_scores_gemma":[0.00007992517,0.0006043149,0.000391704,0.0000049627924,0.00003097329,0.00024526072,0.00001711973,0.0011333654,0.99548125,0.00008537609,0.0019195593,0.0000060628795],"about_ca_topic_score_codex":0.004173327,"about_ca_topic_score_gemma":0.004986155,"teacher_disagreement_score":0.004173327,"about_ca_system_score_codex":0.00074577134,"about_ca_system_score_gemma":0.00079040055,"threshold_uncertainty_score":0.008298099},"labels":[],"label_agreement":null},{"id":"W2092569546","doi":"10.1038/sj.gt.3302218","title":"Genetically engineered Sertoli cells are able to survive allogeneic transplantation","year":2004,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Transplantation; Biology; Green fluorescent protein; Transgene; Renal capsule; Genetically modified mouse; Sertoli cell; Immunology; Cell biology; Genetically modified organism; Kidney; Internal medicine; Medicine; Gene; Endocrinology; Genetics","score_opus":0.01081567881303577,"score_gpt":0.22942277280166207,"score_spread":0.2186070939886263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092569546","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97829914,0.003762826,0.009964133,0.00026951538,0.00016587743,0.000087001754,0.00094328437,0.00053213775,0.005976117],"genre_scores_gemma":[0.9865067,0.0010971971,0.0028439283,0.0000817668,0.000031676216,0.000042891774,0.0010074128,0.00009270358,0.008295794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997762,0.00003307316,0.000020729723,0.000027738004,0.000096147975,0.000046089073],"domain_scores_gemma":[0.9996332,0.00010340574,0.00011495012,0.000049197017,0.000028789647,0.000070379734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024787438,0.0002935438,0.00053655094,0.0003655489,0.00017106286,0.00053050194,0.0002641031,0.00057874445,0.0021379467],"category_scores_gemma":[0.00019915616,0.00021627868,0.0003046978,0.0001934912,0.00032326818,0.00022648791,0.00017790418,0.0010146749,0.0009997974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008385271,0.000025405076,0.00008296223,0.00002488684,0.0000066802886,0.00006961021,0.000013958056,0.00007262081,0.9983241,0.00024162055,0.000057406603,0.0009968389],"study_design_scores_gemma":[0.000033515575,0.00027171872,0.0014569404,0.000004560337,0.000026211663,0.00049165956,0.000014046855,0.00047987627,0.99331516,0.00008463665,0.0038169492,0.0000047254957],"about_ca_topic_score_codex":0.00021133517,"about_ca_topic_score_gemma":0.00041082097,"teacher_disagreement_score":0.0021379467,"about_ca_system_score_codex":0.0001613569,"about_ca_system_score_gemma":0.00016428804,"threshold_uncertainty_score":0.0071521997},"labels":[],"label_agreement":null},{"id":"W2095276165","doi":"10.1038/gt.2013.70","title":"A novel gene therapy strategy using secreted multifunctional anti-HIV proteins to confer protection to gene-modified and unmodified target cells","year":2013,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Genetic enhancement; Biology; Gene delivery; Gene; Virology; Lentivirus; Human immunodeficiency virus (HIV); Computational biology; Genetics; Viral disease","score_opus":0.05634950845673442,"score_gpt":0.296787808672011,"score_spread":0.24043830021527657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095276165","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82533616,0.00446981,0.16239867,0.00076464686,0.0004006377,0.0002674864,0.00026274487,0.0005650991,0.0055346745],"genre_scores_gemma":[0.93120104,0.0019730723,0.058291513,0.00033869228,0.000041305004,0.00013771329,0.00021195659,0.000044518052,0.007760233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999863,0.000018187473,0.0000099853205,0.000035085366,0.000043829743,0.000029781902],"domain_scores_gemma":[0.99994135,0.0000089749055,0.000016400392,0.000009911414,0.000009326181,0.00001397287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024154993,0.0004945172,0.00038115346,0.00020142797,0.00023602167,0.00044904224,0.00040889686,0.0006635149,0.00045651215],"category_scores_gemma":[0.00009992669,0.00022150783,0.0003622679,0.00015014476,0.00036676993,0.0004264822,0.0003581663,0.0008296864,0.00022605041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028040546,0.000027798065,0.000028237544,0.000025777454,0.0000037254385,0.00005927517,0.000018541854,0.000081903236,0.9961558,0.00074714486,0.00007190357,0.0027519525],"study_design_scores_gemma":[0.000018038685,0.00018435273,0.00022835951,0.000002457196,0.000012297948,0.00044100056,0.0000075781,0.0009477455,0.99488896,0.0001418245,0.0031202154,0.000007136905],"about_ca_topic_score_codex":0.00030974287,"about_ca_topic_score_gemma":0.00044541026,"teacher_disagreement_score":0.0006635149,"about_ca_system_score_codex":0.0003139165,"about_ca_system_score_gemma":0.0003283447,"threshold_uncertainty_score":0.0022776723},"labels":[],"label_agreement":null},{"id":"W2127487757","doi":"10.1038/gt.2011.25","title":"Effective and safe gene-based delivery of GLP-1 using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of type 2 diabetes","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Polytechnique Montréal","funders":"Canadian Institutes of Health Research","keywords":"Gene delivery; Genetic enhancement; Furin; Plasmid; Chitosan; Enhancer; Glucagon-like peptide-1; Dipeptidyl peptidase; Biology; Pharmacology; Diabetes mellitus; Type 2 diabetes; Gene; Endocrinology; Biochemistry; Gene expression","score_opus":0.0657103946566432,"score_gpt":0.27477862748648874,"score_spread":0.20906823282984555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127487757","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861385,0.0014428989,0.010200883,0.0003635123,0.00013388731,0.00012354633,0.00020968492,0.00021333156,0.0011736313],"genre_scores_gemma":[0.98767006,0.0010854442,0.007712802,0.000084218766,0.000027005872,0.00009011999,0.00018307669,0.00007474074,0.003072561],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963737,0.000059032336,0.000026056014,0.00007858523,0.000115650924,0.00008313841],"domain_scores_gemma":[0.999736,0.000051610616,0.000088599314,0.000027768598,0.00003137192,0.00006474014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050076935,0.0005484382,0.0006153701,0.0005752128,0.00024388307,0.00052750757,0.00056942925,0.00094262767,0.00074179744],"category_scores_gemma":[0.00030575765,0.00036821753,0.00039802465,0.0002635133,0.0007583058,0.00065224344,0.00027643924,0.001276626,0.0001657912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027116563,0.0000776544,0.000026522495,0.000037656504,0.00000709417,0.000055051038,0.000023268543,0.00016447403,0.9980919,0.00013095255,0.00003689247,0.0010772905],"study_design_scores_gemma":[0.00004849958,0.00045177765,0.00015580519,0.0000036285435,0.000023185732,0.000057149304,0.000008651012,0.00069252163,0.9978269,0.000023596942,0.00070039195,0.00000779312],"about_ca_topic_score_codex":0.0017734481,"about_ca_topic_score_gemma":0.0015387607,"teacher_disagreement_score":0.0017734481,"about_ca_system_score_codex":0.0007510183,"about_ca_system_score_gemma":0.000613125,"threshold_uncertainty_score":0.0054490566},"labels":[],"label_agreement":null},{"id":"W2128054910","doi":"10.1038/gt.2008.94","title":"Syncytia formation affects the yield and cytotoxicity of an adenovirus expressing a fusogenic glycoprotein at a late stage of replication","year":2008,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Oncolytics Biotech; Generalitat de Catalunya; European Commission","keywords":"Biology; Virology; Syncytium; Cytotoxicity; Multiplicity of infection; Virus; Glycoprotein; Viral replication; Molecular biology; Adenoviridae; Viral envelope; Gene; Genetic enhancement; In vitro; Genetics","score_opus":0.035725395377290324,"score_gpt":0.2943277485047488,"score_spread":0.2586023531274585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128054910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99314946,0.0010209671,0.0037919548,0.000051433668,0.000030232748,0.00002612265,0.00024578074,0.000074845186,0.001609228],"genre_scores_gemma":[0.99636614,0.00035113125,0.0010840347,0.000020888272,0.0000060994016,0.000016161244,0.00042503522,0.00003296702,0.0016975277],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99950635,0.00012247887,0.00006903037,0.000068523426,0.00012362846,0.00010992073],"domain_scores_gemma":[0.99905604,0.00044129664,0.00017665752,0.000101658065,0.00010939037,0.00011503888],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006059533,0.0006376356,0.00039185552,0.00052087236,0.00024514453,0.00046302954,0.00028346307,0.00056183286,0.0012046478],"category_scores_gemma":[0.0006723032,0.0002899659,0.00041903672,0.00030846157,0.00037205112,0.00047907638,0.00034865827,0.0007648942,0.00042084654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105493054,0.000014901121,0.0000871835,0.000008668569,0.0000032436217,0.000033439075,0.000011155008,0.000055713106,0.9993734,0.00009590186,0.000008118909,0.00020290152],"study_design_scores_gemma":[0.0000044333988,0.00013891456,0.00063876656,0.0000010642368,0.000006082306,0.000058681177,0.0000070538217,0.00029128362,0.9986272,0.000017586146,0.00020718727,0.0000018154765],"about_ca_topic_score_codex":0.00083454256,"about_ca_topic_score_gemma":0.0005249027,"teacher_disagreement_score":0.0012046478,"about_ca_system_score_codex":0.00060085877,"about_ca_system_score_gemma":0.00031679432,"threshold_uncertainty_score":0.0043595433},"labels":[],"label_agreement":null},{"id":"W2129550547","doi":"10.1038/sj.gt.3302172","title":"An enhanced autogene-based dual-promoter cytoplasmic expression system yields increased gene expression","year":2004,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Inimex Pharmaceuticals (Canada); Innovative Targeting Solutions (Canada); University of British Columbia","funders":"Canadian Institutes of Health Research; Health Research","keywords":"Gene expression; Biology; Regulation of gene expression; Transfection; Reporter gene; Gene; Gene delivery; Molecular biology; Transgene; Therapeutic gene modulation; Genetic enhancement; Cell biology; Genetics; Regulator gene","score_opus":0.016502049593520612,"score_gpt":0.28405414338821017,"score_spread":0.2675520937946896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129550547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9046859,0.0026092995,0.08581198,0.0002137279,0.00015160057,0.0001005273,0.001094827,0.0010408987,0.0042911367],"genre_scores_gemma":[0.9521634,0.0013323865,0.035397,0.00006793365,0.000034697514,0.000085755724,0.0026059484,0.0003696137,0.007943256],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997664,0.00003464979,0.000019314077,0.00006374871,0.00007537533,0.000040610434],"domain_scores_gemma":[0.99972266,0.00006868207,0.00004731253,0.000055004642,0.00004503387,0.00006130421],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003569882,0.0006223186,0.0004884702,0.00036623116,0.00019046181,0.0006135932,0.00035980265,0.0004329415,0.0010666014],"category_scores_gemma":[0.00023045506,0.00025174758,0.00034297368,0.000286678,0.00038708182,0.00042795745,0.0004015955,0.001210687,0.00077720307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039744198,0.000008329311,0.00002785332,0.000014256111,0.0000017343035,0.000010589586,0.000004808656,0.000023840708,0.99904436,0.00017436704,0.000019397927,0.0006306607],"study_design_scores_gemma":[0.0000044841163,0.000036272897,0.00020744937,0.0000018269336,0.0000066447633,0.00008070266,0.000002530751,0.00035956776,0.9982249,0.00002184441,0.0010514626,0.0000021558155],"about_ca_topic_score_codex":0.0003998097,"about_ca_topic_score_gemma":0.0006440335,"teacher_disagreement_score":0.0010666014,"about_ca_system_score_codex":0.0005086782,"about_ca_system_score_gemma":0.00051742187,"threshold_uncertainty_score":0.0036907792},"labels":[],"label_agreement":null},{"id":"W2135686776","doi":"10.1038/gt.2008.21","title":"Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial","year":2008,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":151,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"","keywords":"Immune system; CD8; Peripheral blood mononuclear cell; Oncolytic virus; Immunology; Cytotoxic T cell; Acquired immune system; Perforin; Granzyme B; Biology; Medicine; Internal medicine; In vitro","score_opus":0.06380306575926736,"score_gpt":0.36180605158215984,"score_spread":0.2980029858228925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135686776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99621993,0.00093884,0.0010751137,0.00006804029,0.000042002517,0.00036215739,0.0002805002,0.00002443214,0.0009888556],"genre_scores_gemma":[0.99717075,0.00023491205,0.0004378171,0.00014640567,0.000028770402,0.00029313838,0.0006151166,0.000015831185,0.001057189],"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","domain_scores_codex":[0.99944717,0.00017216077,0.000027951366,0.00007528812,0.00007997734,0.0001974379],"domain_scores_gemma":[0.9994816,0.00020921309,0.00008866897,0.00006907654,0.000051918225,0.00009957158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012246701,0.0004322681,0.00093513326,0.00020375232,0.0002211223,0.00065013766,0.0002638542,0.0005706512,0.0015251152],"category_scores_gemma":[0.0010911588,0.00020394784,0.0003548135,0.00022688581,0.00038510954,0.00041140232,0.00010313722,0.0011589957,0.0003231594],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.069331475,0.009989304,0.010502053,0.00019384142,0.00017695254,0.00044062178,0.00028598306,0.002943835,0.82802916,0.0004978008,0.0011514428,0.07645746],"study_design_scores_gemma":[0.014068506,0.3994497,0.07172935,0.000047611942,0.00063551153,0.00205893,0.00035710045,0.007058345,0.49209872,0.0007377324,0.011703527,0.000054970544],"about_ca_topic_score_codex":0.0003326734,"about_ca_topic_score_gemma":0.00044802378,"teacher_disagreement_score":0.0015251152,"about_ca_system_score_codex":0.0003207585,"about_ca_system_score_gemma":0.00044921975,"threshold_uncertainty_score":0.00647676},"labels":[],"label_agreement":null},{"id":"W2151235295","doi":"10.1038/sj.gt.3302861","title":"Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":203,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotel Dieu Hospital","funders":"Institut National de la Santé et de la Recherche Médicale; Lions Clubs International Foundation","keywords":"RPE65; Biology; Retinal; Retinal pigment epithelium; Genetic enhancement; Electroretinography; Cis-trans-Isomerases; Adeno-associated virus; Gene delivery; Retina; Retinal degeneration; Vector (molecular biology); Recombinant DNA; Genetics; Neuroscience; Gene","score_opus":0.021041593945190742,"score_gpt":0.26493080956049886,"score_spread":0.24388921561530813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151235295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99568886,0.0006750512,0.001758792,0.00023376259,0.00006265146,0.00002885084,0.00019519769,0.00015210685,0.0012047316],"genre_scores_gemma":[0.9867932,0.0007682166,0.0026867122,0.00008078463,0.000019794292,0.000042280328,0.00031668693,0.000091123766,0.0092011215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996966,0.000037732083,0.000035058656,0.00007493624,0.000079467456,0.00007618239],"domain_scores_gemma":[0.999474,0.000080873804,0.00021292885,0.00005309664,0.000043455282,0.00013570033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046704925,0.0004261839,0.0005683478,0.0012178863,0.0004386615,0.00048037944,0.00034939995,0.0009764262,0.0024741266],"category_scores_gemma":[0.00060966134,0.00048484353,0.00029885492,0.0002052369,0.00089461135,0.0008037676,0.00028248644,0.0009352957,0.000528941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012356902,0.00023749056,0.00078689354,0.000074163305,0.000022048052,0.00073122105,0.00013361442,0.00019851161,0.9925114,0.0007582403,0.00030297565,0.0030078061],"study_design_scores_gemma":[0.000298755,0.003618256,0.019974962,0.000060948372,0.00014310562,0.007779575,0.0003977596,0.003598752,0.9557487,0.0007197006,0.0075915344,0.00006809444],"about_ca_topic_score_codex":0.0021985143,"about_ca_topic_score_gemma":0.0025213703,"teacher_disagreement_score":0.0024741266,"about_ca_system_score_codex":0.0005947429,"about_ca_system_score_gemma":0.00040531193,"threshold_uncertainty_score":0.008276761},"labels":[],"label_agreement":null},{"id":"W2169546990","doi":"10.1038/sj.gt.3302824","title":"Local gene transfer to calcified tissue cells using prolonged infusion of a lentiviral vector","year":2006,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Hôpital de l'Enfant-Jésus; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Green fluorescent protein; Calvaria; Viral vector; Cell biology; In vivo; Gene delivery; Biology; Transduction (biophysics); Genetic enhancement; In vitro; Molecular biology; Transgene; Cell culture; Transfection; Gene; Biochemistry; Recombinant DNA","score_opus":0.022452392314883,"score_gpt":0.29537605895845664,"score_spread":0.27292366664357365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169546990","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90978295,0.005202229,0.080677085,0.00020419633,0.00017380017,0.00031875554,0.0005399816,0.00059571455,0.0025052691],"genre_scores_gemma":[0.9689678,0.0017695994,0.02247191,0.00006529805,0.00006118328,0.00021787533,0.000554396,0.00012501868,0.0057668737],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997663,0.0000211993,0.000025459301,0.00007538668,0.000056776647,0.000054884527],"domain_scores_gemma":[0.9997485,0.0000523359,0.00007160786,0.000051361727,0.000024036213,0.000052074814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005336944,0.00048792592,0.00062070444,0.0005039616,0.00027499895,0.0007290363,0.00050585106,0.00052543933,0.0009142643],"category_scores_gemma":[0.0002272814,0.00028363528,0.0005330581,0.0003562423,0.00057860743,0.0005077774,0.00045009603,0.0011077478,0.000317072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007890875,0.000024338808,0.000082274484,0.000030508989,0.000008509151,0.000041829335,0.0000320173,0.00008682115,0.9970855,0.00043952707,0.000033011747,0.0020567554],"study_design_scores_gemma":[0.000037466863,0.00029425346,0.0006660773,0.000009128417,0.000040223153,0.00021913866,0.000014190052,0.00087535253,0.9951768,0.000106327694,0.002554921,0.0000061582336],"about_ca_topic_score_codex":0.0010101584,"about_ca_topic_score_gemma":0.0015749991,"teacher_disagreement_score":0.0010101584,"about_ca_system_score_codex":0.00057236897,"about_ca_system_score_gemma":0.0006478865,"threshold_uncertainty_score":0.0041528344},"labels":[],"label_agreement":null},{"id":"W2236091866","doi":"10.1038/gt.2016.2","title":"Establishment of two quantitative nested qPCR assays targeting the human EPO transgene","year":2016,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"World Anti-Doping Agency; University of Florida","keywords":"Biology; Complementary DNA; Recombinant DNA; Transgene; Virology; Vector (molecular biology); Real-time polymerase chain reaction; Molecular biology; Gene; Plasmid; Computational biology; Genetics","score_opus":0.040731074511516134,"score_gpt":0.3444457529791858,"score_spread":0.30371467846766964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2236091866","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11806674,0.00086234947,0.8660605,0.00044041628,0.0008343838,0.003929543,0.0025845089,0.0033208749,0.003900661],"genre_scores_gemma":[0.14515649,0.00079785543,0.8193957,0.00066212827,0.00021049005,0.012137145,0.006201885,0.0013307214,0.014107579],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9895076,0.0020386428,0.00096013653,0.0032019662,0.002998932,0.001292629],"domain_scores_gemma":[0.9920563,0.0034822654,0.00079896493,0.001073803,0.0019789531,0.0006096794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00730086,0.0043842928,0.0027347356,0.0022997994,0.0009281284,0.0016893076,0.0023953768,0.0020791336,0.004927967],"category_scores_gemma":[0.007278554,0.0035623144,0.0024294795,0.001029698,0.00279713,0.0016482585,0.0019138568,0.006172963,0.0029820958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014524862,0.00017029661,0.00030321445,0.00015428345,0.000017134025,0.000032398097,0.00018896571,0.00018628426,0.99491197,0.0010019407,0.0001757951,0.0027125124],"study_design_scores_gemma":[0.000060969935,0.00035169307,0.0009066487,0.000034576606,0.000056349585,0.00009374019,0.00005587493,0.004200399,0.98984945,0.0004925224,0.0038483192,0.00004931613],"about_ca_topic_score_codex":0.0018400915,"about_ca_topic_score_gemma":0.004206041,"teacher_disagreement_score":0.00730086,"about_ca_system_score_codex":0.001757546,"about_ca_system_score_gemma":0.0031166968,"threshold_uncertainty_score":0.038611054},"labels":[],"label_agreement":null},{"id":"W2285359655","doi":"10.1038/gt.2015.95","title":"Lymphopoiesis in transgenic mice over-expressing Artemis","year":2015,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut National Du Cancer; Ligue Contre le Cancer; Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale","keywords":"Transgene; Biology; Genetic enhancement; Lymphopoiesis; Genetically modified mouse; Enhancer; Severe combined immunodeficiency; Haematopoiesis; Homologous recombination; Transplantation; Gene; Stem cell; Cancer research; Humanized mouse; Gene targeting; Immunology; Genetics; Gene expression; Medicine; Immune system","score_opus":0.08276522852367603,"score_gpt":0.3484479986844704,"score_spread":0.2656827701607944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2285359655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98160017,0.0015525052,0.006910454,0.00048637623,0.00025850593,0.0001387336,0.001935832,0.00082858093,0.0062889266],"genre_scores_gemma":[0.97298664,0.0009896249,0.0042127105,0.00025500404,0.000087678454,0.00018879255,0.0012554504,0.0003168109,0.019707283],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999624,0.000055035995,0.00003843022,0.00010536254,0.00008814467,0.000089037436],"domain_scores_gemma":[0.9994261,0.00013300584,0.00017510353,0.00005661542,0.00003935877,0.00016981913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034709804,0.0007070916,0.00048360057,0.001600546,0.0004242761,0.000678744,0.000443172,0.0009680105,0.004913701],"category_scores_gemma":[0.0002539166,0.00040708968,0.00048823113,0.0003921885,0.0009363172,0.0006992516,0.00032546933,0.0021464285,0.001056179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005041284,0.000067442365,0.0001384539,0.00002911774,0.0000069852595,0.00012117557,0.000045462988,0.00006051655,0.99745363,0.00051015045,0.000060075337,0.0010028075],"study_design_scores_gemma":[0.00015420224,0.00049566716,0.0010298209,0.000013810192,0.000064915956,0.00039861642,0.0000621574,0.0008044313,0.9932546,0.00029979844,0.003410422,0.000011725533],"about_ca_topic_score_codex":0.00059914024,"about_ca_topic_score_gemma":0.0005949031,"teacher_disagreement_score":0.004913701,"about_ca_system_score_codex":0.00048541257,"about_ca_system_score_gemma":0.00036407166,"threshold_uncertainty_score":0.016437948},"labels":[],"label_agreement":null},{"id":"W2312371445","doi":"10.1038/sj.gt.3301602","title":"Designing gene therapy vectors: avoiding immune responses by using tissue-specific promoters","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Genetic enhancement; Biology; Immune system; DNA vaccination; Transfection; HBsAg; Antigen; Immunology; Promoter; Molecular biology; Gene; Gene expression; Immunization; Genetics; Hepatitis B virus; Virus","score_opus":0.05701211222923673,"score_gpt":0.32409829736233164,"score_spread":0.2670861851330949,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2312371445","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23964345,0.008272715,0.7446673,0.00085429533,0.0003686828,0.00081531116,0.00020656594,0.0006446632,0.0045270403],"genre_scores_gemma":[0.45237088,0.011794894,0.5251756,0.000644876,0.00009537582,0.001019965,0.0005697896,0.00035597815,0.007972624],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99950504,0.00014074994,0.00004417656,0.0000884098,0.00014099391,0.00008057222],"domain_scores_gemma":[0.99964225,0.00011900061,0.00009201479,0.000031613316,0.00006849184,0.00004656754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013102301,0.00095082057,0.0006316175,0.0005155919,0.0004596009,0.0009500988,0.00058277615,0.0009897065,0.00058332493],"category_scores_gemma":[0.00086246803,0.0005491496,0.00044735576,0.00040102316,0.0008576641,0.0012230449,0.00039827666,0.0014627317,0.0006493525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072372,0.000048589605,0.00016906843,0.00022204728,0.000007467208,0.00007078206,0.00009357928,0.00053116144,0.9832424,0.004337583,0.00017279493,0.011032161],"study_design_scores_gemma":[0.000021645777,0.0001358432,0.00009961436,0.000023150995,0.000021127702,0.00020092394,0.000027011176,0.0010504255,0.9899955,0.0008465573,0.0075676665,0.0000105633735],"about_ca_topic_score_codex":0.00027290528,"about_ca_topic_score_gemma":0.00042059808,"teacher_disagreement_score":0.0013102301,"about_ca_system_score_codex":0.00049529487,"about_ca_system_score_gemma":0.0006399095,"threshold_uncertainty_score":0.006929219},"labels":[],"label_agreement":null},{"id":"W2312529624","doi":"10.1038/sj.gt.3301675","title":"Human cytidine deaminase as an ex vivo drug selectable marker in gene-modified primary bone marrow stromal cells","year":2002,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; Université de Montréal; McGill University Health Centre; McGill University","funders":"","keywords":"Cytosine deaminase; Ex vivo; Biology; Molecular biology; Cytidine deaminase; Selectable marker; Mesenchymal stem cell; Bone marrow; Stromal cell; Genetic enhancement; In vivo; Transgene; Cancer research; Cell biology; Gene; Immunology; Biochemistry; Genetics","score_opus":0.018078975082978448,"score_gpt":0.2745251322596951,"score_spread":0.25644615717671665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2312529624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96146226,0.0028314958,0.031016763,0.00014288303,0.00009131807,0.00010264484,0.00072766695,0.0003270906,0.0032979136],"genre_scores_gemma":[0.9802713,0.0010287652,0.0139909685,0.000029962455,0.000016104246,0.000048323458,0.00054311607,0.00007728653,0.0039942036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997998,0.00004622575,0.000021809565,0.000044846445,0.000049377173,0.000037956182],"domain_scores_gemma":[0.99981886,0.000067317866,0.000026280424,0.000035733705,0.000020420774,0.00003152484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026464628,0.00029687386,0.00036374974,0.00023931351,0.00018043717,0.00045889232,0.00028113255,0.00027261217,0.0008433087],"category_scores_gemma":[0.00015428141,0.00019339785,0.00019215384,0.00026074098,0.00022426064,0.0002381329,0.00019598931,0.0005436365,0.00043591988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006307569,0.000008052511,0.000053567644,0.000013834645,0.000001831836,0.000026690586,0.000010129329,0.000053647298,0.9989343,0.00015818424,0.000018861647,0.0006578062],"study_design_scores_gemma":[0.000004007751,0.000033253873,0.00017890403,7.931681e-7,0.0000035916717,0.00005342608,0.0000022890379,0.00027270554,0.99869734,0.0000095965615,0.00074330386,8.4099526e-7],"about_ca_topic_score_codex":0.0010899273,"about_ca_topic_score_gemma":0.0024360442,"teacher_disagreement_score":0.0010899273,"about_ca_system_score_codex":0.0003499982,"about_ca_system_score_gemma":0.00029411723,"threshold_uncertainty_score":0.0028211474},"labels":[],"label_agreement":null},{"id":"W2312848410","doi":"10.1038/sj.gt.3301193","title":"Pretreatment with cationic lipid-mediated transfer of the Na+K+-ATPase pump in a mouse model in vivo augments resolution of high permeability pulmonary oedema","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôtel-Dieu de Montréal","funders":"Wellcome Trust","keywords":"In vivo; Molecular biology; Biology; Lung; Ex vivo; Pharmacology; Chemistry; Internal medicine; Medicine","score_opus":0.03264184285313324,"score_gpt":0.3070427405321099,"score_spread":0.27440089767897663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2312848410","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98503983,0.0016668676,0.010174584,0.0006856166,0.0002427556,0.00012984408,0.00029393888,0.0004663731,0.001300274],"genre_scores_gemma":[0.98409516,0.0016083649,0.0073993676,0.00013577027,0.00008585238,0.00015396382,0.00034838828,0.0001169866,0.0060562114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999567,0.00006515132,0.00003855055,0.0001056599,0.000076971985,0.00014657284],"domain_scores_gemma":[0.9994636,0.00009777141,0.00016748896,0.000060571805,0.00003406683,0.00017644261],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005479053,0.0010914635,0.00089294737,0.0008444854,0.0003501676,0.0006825959,0.00059832,0.0014931167,0.0017613539],"category_scores_gemma":[0.00034728984,0.00042073522,0.00055707106,0.0002803387,0.0012685987,0.0010537354,0.00030392813,0.0021837116,0.00054144184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047371926,0.000113014285,0.000040311472,0.000030801853,0.000004416682,0.000066184206,0.000024295205,0.00005707519,0.9983012,0.00016626446,0.000035247715,0.00068747543],"study_design_scores_gemma":[0.00009554051,0.0016389127,0.00058229815,0.0000096034855,0.000024770112,0.0001851363,0.00003476724,0.00055389764,0.9958548,0.00010940629,0.0009016234,0.000009062064],"about_ca_topic_score_codex":0.0006921804,"about_ca_topic_score_gemma":0.0009990409,"teacher_disagreement_score":0.0017613539,"about_ca_system_score_codex":0.00040438163,"about_ca_system_score_gemma":0.00048850744,"threshold_uncertainty_score":0.0058922768},"labels":[],"label_agreement":null},{"id":"W2313495547","doi":"10.1038/sj.gt.3301208","title":"Helper-dependent adenovirus vectors: their use as a gene delivery system to neurons","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Ottawa Hospital; Institute for Biological Sciences; University of Ottawa","funders":"Medical Research Council; National Institutes of Health","keywords":"Biology; Gene delivery; Viral vector; Cytotoxic T cell; Viability assay; Cell biology; Genetic enhancement; Adenoviridae; Transfection; Immunology; Virology; Recombinant DNA; Molecular biology; Cell culture; Gene; In vitro; Genetics","score_opus":0.02651681163802154,"score_gpt":0.2756756798975427,"score_spread":0.24915886825952116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2313495547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.49126175,0.102435954,0.37574175,0.0012528647,0.0010188001,0.0007087775,0.0017301459,0.0012549252,0.024594987],"genre_scores_gemma":[0.7693813,0.06865402,0.13004553,0.00016588658,0.0001931844,0.00029419526,0.0015015868,0.00020050908,0.029563839],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998808,0.000020989119,0.0000096380445,0.000021657039,0.00004909642,0.000017825401],"domain_scores_gemma":[0.99988806,0.000036387668,0.000016827436,0.000015856473,0.000019487357,0.000023428984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052738516,0.00044503764,0.00034306524,0.0005876777,0.0002636731,0.00068505574,0.0004264991,0.00039943634,0.00078776997],"category_scores_gemma":[0.00023894964,0.00041609685,0.00024414528,0.00038677035,0.0005290383,0.000692608,0.0002683894,0.0009550574,0.000614248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003773445,0.000047356756,0.00021770276,0.00025640157,0.000019724936,0.00014754012,0.00011194863,0.00019452596,0.9534252,0.007955938,0.00057119236,0.036675062],"study_design_scores_gemma":[0.00004911339,0.00022164274,0.00044002102,0.000016129228,0.000041601295,0.00048029266,0.000024046325,0.0005692577,0.9713507,0.0012291359,0.025564829,0.000013291399],"about_ca_topic_score_codex":0.00086770725,"about_ca_topic_score_gemma":0.00103395,"teacher_disagreement_score":0.00086770725,"about_ca_system_score_codex":0.00052308093,"about_ca_system_score_gemma":0.00056979165,"threshold_uncertainty_score":0.0037952065},"labels":[],"label_agreement":null},{"id":"W2313802299","doi":"10.1038/sj.gt.3301348","title":"Identification of polyamides that enhance adenovirus-mediated gene expression in the urothelium","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Urothelium; Transgene; Genetic enhancement; Biology; Cancer research; Adenoviridae; Gene delivery; Viral vector; Gene expression; Bladder cancer; Gene; Molecular biology; Cancer; Anatomy","score_opus":0.02421494156231809,"score_gpt":0.30899220073449896,"score_spread":0.2847772591721809,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2313802299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98608,0.0027419073,0.0087909,0.00007003377,0.00003436042,0.000055677974,0.00012744353,0.000055377033,0.002044271],"genre_scores_gemma":[0.9854908,0.0015336775,0.010559293,0.000043603948,0.000019344152,0.00003890173,0.0002430936,0.000028553492,0.0020427047],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998727,0.000028000415,0.000011188748,0.00002334472,0.00002527548,0.00003944431],"domain_scores_gemma":[0.9997632,0.00006971434,0.000050975268,0.00002263194,0.000037294056,0.00005615869],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036756223,0.00033476079,0.0002203833,0.0003099919,0.00012165609,0.00038546105,0.00014713993,0.00026024002,0.0007316881],"category_scores_gemma":[0.0002921475,0.0001844596,0.0002455127,0.00014511857,0.00019919204,0.00025714026,0.00015923088,0.00032431338,0.00025387522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007862296,0.000010987002,0.000055775905,0.000015390904,0.0000017659756,0.000014679578,0.0000041104436,0.00004561031,0.99910575,0.00008085233,0.0000053633203,0.00058099045],"study_design_scores_gemma":[0.000019083436,0.00022702258,0.0007691377,0.000004143093,0.000012796286,0.00008280452,0.0000072316734,0.00022997746,0.9976586,0.00003440517,0.00095232687,0.0000024624576],"about_ca_topic_score_codex":0.0002912784,"about_ca_topic_score_gemma":0.0003699192,"teacher_disagreement_score":0.0007316881,"about_ca_system_score_codex":0.000269729,"about_ca_system_score_gemma":0.00019864581,"threshold_uncertainty_score":0.0024477243},"labels":[],"label_agreement":null},{"id":"W2315176998","doi":"10.1038/sj.gt.3301132","title":"Telomerase allows the immortalization of T antigen-positive DMD myoblasts: a new source of cells for gene transfer application","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"University of Texas Southwestern Medical Center","keywords":"Telomerase; Telomere; Myocyte; Biology; Telomerase reverse transcriptase; Transplantation; Retrovirus; Cell biology; Cancer research; Immunology; Molecular biology; Cell culture; Genetics; Gene; Medicine; Internal medicine","score_opus":0.012736659487267037,"score_gpt":0.24996825093431363,"score_spread":0.23723159144704659,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2315176998","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8630294,0.017694313,0.10625107,0.0011109116,0.0003448836,0.00017163319,0.00115646,0.00071827293,0.00952311],"genre_scores_gemma":[0.9548065,0.009786708,0.024348408,0.000113239956,0.00008647157,0.000094503695,0.00096632435,0.00011039333,0.009687364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988663,0.000020847046,0.000016296768,0.000019591309,0.000043958873,0.000012593755],"domain_scores_gemma":[0.9998826,0.000037081732,0.000019968109,0.000027160173,0.000013489197,0.000019654632],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039112516,0.00023017947,0.00028483686,0.00053976994,0.00029195484,0.00047893554,0.00021091502,0.0004465337,0.0014482649],"category_scores_gemma":[0.00024540082,0.0001894208,0.0002691515,0.00022233302,0.0002424542,0.00029767764,0.0002943321,0.0007792925,0.0005201019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055441527,0.000012823746,0.00012516207,0.000032282027,0.0000030717524,0.00007393011,0.000025418785,0.000031355907,0.99463177,0.0007403524,0.00010847887,0.0041598002],"study_design_scores_gemma":[0.000030100215,0.00017364149,0.0012161911,0.000011891832,0.00002942258,0.0008711626,0.000023546034,0.00051293196,0.9838358,0.00026585866,0.01302287,0.0000064977316],"about_ca_topic_score_codex":0.00029067916,"about_ca_topic_score_gemma":0.0005851363,"teacher_disagreement_score":0.0014482649,"about_ca_system_score_codex":0.00017141522,"about_ca_system_score_gemma":0.00022689403,"threshold_uncertainty_score":0.0048449636},"labels":[],"label_agreement":null},{"id":"W2316469384","doi":"10.1038/sj.gt.3301396","title":"Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"Hamilton Health Sciences","keywords":"CTL*; Immune system; Genetic enhancement; Immunology; Cytotoxic T cell; CD8; Cancer research; Biology; Immunization; ErbB; Dendritic cell; Immunity; Acquired immune system; Cancer; Medicine; Gene; In vitro","score_opus":0.035896840908929334,"score_gpt":0.2624634454839267,"score_spread":0.22656660457499736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2316469384","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891639,0.001837216,0.006166716,0.00023106778,0.0001420234,0.0001398054,0.00031900036,0.00021984873,0.001780526],"genre_scores_gemma":[0.9943817,0.0007532461,0.0029980855,0.00005003575,0.000035157675,0.000078940415,0.00022003977,0.00003148603,0.0014512705],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997037,0.000052061067,0.000030105472,0.000041505118,0.00006099106,0.00011150361],"domain_scores_gemma":[0.9998109,0.00004790894,0.00004113205,0.000039121496,0.000015935744,0.00004502891],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042103455,0.00078419945,0.0006295206,0.00051074283,0.00020043863,0.00059366826,0.0003107586,0.00066630245,0.0010089917],"category_scores_gemma":[0.00021612905,0.00029951008,0.0004271564,0.00034132646,0.000452171,0.00042994026,0.00029035483,0.0019603167,0.0004514249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006387796,0.0002691872,0.0000895419,0.00004191073,0.000008867371,0.000046507277,0.00001953256,0.00025072804,0.99559504,0.00029507867,0.00006879402,0.0026759438],"study_design_scores_gemma":[0.00010168294,0.00045773454,0.00034229632,0.0000029289447,0.000023871191,0.000094657975,0.0000066758257,0.00097419776,0.9972395,0.00004711483,0.0007060781,0.0000032673338],"about_ca_topic_score_codex":0.00032497573,"about_ca_topic_score_gemma":0.00035519947,"teacher_disagreement_score":0.0010089917,"about_ca_system_score_codex":0.00041327276,"about_ca_system_score_gemma":0.00033518905,"threshold_uncertainty_score":0.003375411},"labels":[],"label_agreement":null},{"id":"W2316679322","doi":"10.1038/sj.gt.3301123","title":"Regulation of T-helper-1 versus T-helper-2 activity and enhancement of tumor immunity by combined DNA-based vaccination and nonviral cytokine gene transfer","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CTL*; Biology; Immune system; DNA vaccination; Immunity; Carcinoembryonic antigen; Cellular immunity; Antigen; Immunology; Immunization; Cancer","score_opus":0.01202781273986617,"score_gpt":0.23326523388218945,"score_spread":0.22123742114232328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2316679322","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896752,0.0027710553,0.0055443225,0.00012270102,0.000105305255,0.000091373164,0.00012473995,0.00012729912,0.0014379281],"genre_scores_gemma":[0.99504364,0.0005172087,0.0028962982,0.00004100454,0.000069606605,0.00007830479,0.000105368395,0.000034202138,0.0012144587],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994518,0.00011681686,0.00003956402,0.00010354603,0.00010076843,0.00018751231],"domain_scores_gemma":[0.9995906,0.00017102777,0.00009659282,0.000037191796,0.000028063027,0.0000764707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005579391,0.0006882213,0.00060509396,0.00068201165,0.00016348886,0.00072087406,0.0004111867,0.00058956776,0.0014144705],"category_scores_gemma":[0.00036071587,0.00030653752,0.0003954762,0.0002866037,0.00061160227,0.000482524,0.00029799767,0.0012565126,0.0003354302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069568853,0.00011607162,0.00011254511,0.00003407904,0.0000054532075,0.000019993742,0.000013853605,0.00014147087,0.9970176,0.00016725872,0.000015168789,0.0016608015],"study_design_scores_gemma":[0.000095493844,0.0009035763,0.00075061567,0.000003675471,0.000020106096,0.00007289168,0.00001030892,0.0010949123,0.9965243,0.00007297634,0.00044737113,0.000003776714],"about_ca_topic_score_codex":0.00020710085,"about_ca_topic_score_gemma":0.00040849147,"teacher_disagreement_score":0.0014144705,"about_ca_system_score_codex":0.00044329898,"about_ca_system_score_gemma":0.00038660204,"threshold_uncertainty_score":0.0047318935},"labels":[],"label_agreement":null},{"id":"W2316707305","doi":"10.1038/sj.gt.3301066","title":"Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Muscular Dystrophy Association","keywords":"Utrophin; Dystrophin; Minigene; Muscular dystrophy; mdx mouse; Biology; Duchenne muscular dystrophy; Cell biology; Molecular biology; Internal medicine; Endocrinology; Genetics; Medicine; Alternative splicing; Messenger RNA; Gene","score_opus":0.009920279153050882,"score_gpt":0.2327830201706822,"score_spread":0.22286274101763132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2316707305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846694,0.002220682,0.009885708,0.00031458848,0.00017836007,0.00012114572,0.00050401647,0.00030409504,0.0018021909],"genre_scores_gemma":[0.98572075,0.001349325,0.005501322,0.000068111076,0.000042538435,0.00009963674,0.00059377943,0.000076421966,0.006548024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997271,0.000050838316,0.00004438182,0.000049084007,0.00004828558,0.00008039285],"domain_scores_gemma":[0.999607,0.00011520182,0.0000900092,0.000065157714,0.000034272598,0.0000883497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046193623,0.0007515419,0.00048502124,0.00049130537,0.00032449464,0.000390217,0.00039069695,0.00048023244,0.001295148],"category_scores_gemma":[0.00028060903,0.00033824134,0.00048667623,0.00021486828,0.0005660486,0.00038478422,0.00028836523,0.00087323115,0.00046045138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024310546,0.00005978825,0.000063976346,0.000043655757,0.000007397357,0.000045639146,0.000020673917,0.000084611536,0.998116,0.00029941974,0.000046371562,0.0009694222],"study_design_scores_gemma":[0.00005157328,0.00037999277,0.0009352096,0.0000068349914,0.000025042069,0.00016462876,0.000016542264,0.0006908913,0.99664706,0.000055819823,0.0010218548,0.000004486722],"about_ca_topic_score_codex":0.0017015857,"about_ca_topic_score_gemma":0.0017436004,"teacher_disagreement_score":0.0017015857,"about_ca_system_score_codex":0.00040773867,"about_ca_system_score_gemma":0.0005808148,"threshold_uncertainty_score":0.0043327212},"labels":[],"label_agreement":null},{"id":"W2317994951","doi":"10.1038/sj.gt.3301309","title":"Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Western University; Robarts Clinical Trials","funders":"","keywords":"Insulitis; NOD mice; Genetic enhancement; Nod; Viral vector; Immunology; Adenoviridae; Biology; Vector (molecular biology); Gene delivery; Immune system; Immunotherapy; Diabetes mellitus; Virology; Recombinant DNA; Gene; Autoimmunity; Endocrinology","score_opus":0.011964924450254892,"score_gpt":0.2541074546100432,"score_spread":0.2421425301597883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2317994951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990415,0.0018292828,0.0054764906,0.00025081055,0.00016876549,0.000108084096,0.0002924874,0.00022561898,0.0012335684],"genre_scores_gemma":[0.9867884,0.002285693,0.0054246727,0.00009919039,0.00009925417,0.0002281504,0.00051420054,0.00006532742,0.004495087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975437,0.000047347658,0.000022501581,0.00004740716,0.00004893806,0.000079399935],"domain_scores_gemma":[0.9998012,0.00003432132,0.00006603021,0.000036116926,0.0000107919,0.00005150286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003746272,0.00088770007,0.0005331917,0.000507692,0.00018869631,0.00041624485,0.00035492293,0.00051555084,0.0010091604],"category_scores_gemma":[0.00017048935,0.00026522548,0.000493154,0.00023828597,0.00042915915,0.00033903518,0.00019069677,0.0016853365,0.000311687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008318984,0.00037697513,0.0002160356,0.00006195104,0.000011534647,0.00006921454,0.000018938577,0.00015165571,0.99534553,0.00029959984,0.000077035154,0.0025395758],"study_design_scores_gemma":[0.00044180843,0.0024682633,0.0018363034,0.000016895763,0.00006962384,0.00039572056,0.000023071405,0.001564815,0.9905724,0.0001599658,0.0024412759,0.000009879509],"about_ca_topic_score_codex":0.00027971025,"about_ca_topic_score_gemma":0.0004454328,"teacher_disagreement_score":0.0010091604,"about_ca_system_score_codex":0.00031005486,"about_ca_system_score_gemma":0.00045643508,"threshold_uncertainty_score":0.003376007},"labels":[],"label_agreement":null},{"id":"W2319994857","doi":"10.1038/sj.gt.3301482","title":"Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":68,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; U.S. Department of Veterans Affairs","keywords":"CpG site; Biology; DNA methylation; DNA; Immune system; Molecular biology; Plasmid; Methylated DNA immunoprecipitation; Gene; Biochemistry; Gene expression; Immunology","score_opus":0.00990124411316648,"score_gpt":0.24110257281769265,"score_spread":0.23120132870452617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2319994857","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9527179,0.01249459,0.025266642,0.00025575826,0.00012467183,0.00018043508,0.00032802013,0.00016092183,0.008471036],"genre_scores_gemma":[0.98295087,0.0030043945,0.008340707,0.000110543304,0.00003303843,0.00007762103,0.00035537683,0.000025815618,0.005101609],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999193,0.000017150343,0.0000041689605,0.000012207697,0.000023890003,0.000023333878],"domain_scores_gemma":[0.99991035,0.000029294175,0.000017565788,0.0000078213025,0.000016405296,0.000018504912],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027375142,0.00036592403,0.0002527512,0.00024837523,0.00012836339,0.000285519,0.0003030699,0.00027707542,0.0017777485],"category_scores_gemma":[0.00027433303,0.0001672539,0.00019935964,0.000118455195,0.00016492039,0.00017126017,0.0001914481,0.00053857896,0.00030847156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035129997,0.00004395894,0.00017429727,0.000047787747,0.000009666586,0.00003730686,0.000010341341,0.0003501821,0.9902042,0.00069992745,0.00006253601,0.00800853],"study_design_scores_gemma":[0.000023428684,0.00033278225,0.0005157244,0.000005029224,0.000017741371,0.000085267224,0.0000051941265,0.0010997378,0.99504197,0.000115866365,0.0027537476,0.0000033910023],"about_ca_topic_score_codex":0.00031347416,"about_ca_topic_score_gemma":0.00064565014,"teacher_disagreement_score":0.0017777485,"about_ca_system_score_codex":0.0002634633,"about_ca_system_score_gemma":0.00019985504,"threshold_uncertainty_score":0.005947113},"labels":[],"label_agreement":null},{"id":"W2323505647","doi":"10.1038/sj.gt.3301506","title":"On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":595,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Inimex Pharmaceuticals (Canada); University of British Columbia","funders":"Medical Research Council Canada","keywords":"Cationic polymerization; Cationic liposome; Endosome; Transfection; Intracellular; Nucleic acid; Oligonucleotide; Biophysics; Biochemistry; Cytoplasm; Lipid bilayer; Biology; Cell biology; Chemistry; Membrane; DNA; Gene; Organic chemistry","score_opus":0.013545267152691703,"score_gpt":0.22541672228070003,"score_spread":0.21187145512800834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2323505647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69279027,0.13941303,0.107692555,0.009185448,0.0020008776,0.0005818448,0.000349324,0.0007181204,0.047268547],"genre_scores_gemma":[0.8876293,0.07642914,0.0127234645,0.0010384361,0.00032737458,0.0002028301,0.00014549725,0.00010622009,0.021397714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998109,0.000032821958,0.00001340025,0.00003404677,0.00005869607,0.000050294162],"domain_scores_gemma":[0.9998233,0.00009936861,0.00002264198,0.000012884707,0.000027003036,0.00001476877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074278103,0.00054588687,0.00038685295,0.00051286985,0.0006024038,0.0008021272,0.0006764315,0.0007368564,0.0021901284],"category_scores_gemma":[0.00045881956,0.00027161805,0.0003332883,0.00031484652,0.0010619992,0.0015354676,0.0005730183,0.0010778203,0.0007460383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010154077,0.00008029573,0.00009714996,0.00066780346,0.00001985782,0.00052686274,0.00025136909,0.0009841511,0.9391356,0.028378854,0.0008487841,0.02799383],"study_design_scores_gemma":[0.000083252584,0.00048979797,0.00029225508,0.00007211882,0.000034798068,0.00032101368,0.00007192944,0.0018427728,0.96704936,0.0051363856,0.02456823,0.000038013695],"about_ca_topic_score_codex":0.0008271565,"about_ca_topic_score_gemma":0.00086744485,"teacher_disagreement_score":0.0021901284,"about_ca_system_score_codex":0.0009255991,"about_ca_system_score_gemma":0.00060447655,"threshold_uncertainty_score":0.0073267817},"labels":[],"label_agreement":null},{"id":"W2324598527","doi":"10.1038/sj.gt.3301895","title":"Prostate targeting: PSP94 gene promoter/enhancer region directed prostate tissue-specific expression in a transgenic mouse prostate cancer model","year":2002,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Prostate cancer; Enhancer; Biology; Transgene; Prostate; Genetically modified mouse; Gene; Gene expression; Genetic enhancement; Cancer research; Cancer; Genetics","score_opus":0.055886283546264987,"score_gpt":0.31204674756866363,"score_spread":0.25616046402239867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2324598527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8958996,0.0038686842,0.073133074,0.0018080872,0.0005058264,0.0005545504,0.006007209,0.0029134331,0.015309654],"genre_scores_gemma":[0.9421109,0.0021977024,0.024420058,0.00029961695,0.00006737085,0.00030156685,0.0037404667,0.00046152598,0.026400795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994917,0.000055688786,0.000034909994,0.00012603491,0.00019118602,0.00010042267],"domain_scores_gemma":[0.9997627,0.000037248894,0.00006053483,0.000041169038,0.000024220988,0.0000741817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003749434,0.0006563538,0.00053278124,0.0016553239,0.00053131056,0.0006095172,0.0008877305,0.0008757572,0.0029808003],"category_scores_gemma":[0.00018954853,0.0005821635,0.00086670625,0.00075654854,0.0007121833,0.00047090565,0.00043603586,0.002286279,0.0011982066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022481127,0.00014168165,0.00015945703,0.00004222073,0.000016140199,0.0001402173,0.00002690024,0.0002234838,0.9955878,0.0009014032,0.00035062467,0.0021853196],"study_design_scores_gemma":[0.00004924499,0.00019401597,0.00083115115,0.000007789668,0.000034982924,0.00054271513,0.000016571572,0.001108794,0.9932805,0.00012224793,0.0038045489,0.0000075679986],"about_ca_topic_score_codex":0.0026104727,"about_ca_topic_score_gemma":0.0030823583,"teacher_disagreement_score":0.0029808003,"about_ca_system_score_codex":0.00075885653,"about_ca_system_score_gemma":0.0006961802,"threshold_uncertainty_score":0.009971738},"labels":[],"label_agreement":null},{"id":"W2324783945","doi":"10.1038/sj.gt.3303059","title":"Vascular endothelial growth factor reduced hypoxia-induced death of human myoblasts and improved their engraftment in mouse muscles","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto; Université Laval; Centre hospitalier de l'Université Laval","funders":"Université Laval","keywords":"Myocyte; Transplantation; Duchenne muscular dystrophy; Biology; Dystrophin; Electroporation; Vascular endothelial growth factor; Hypoxia (environmental); Molecular biology; Andrology; Immunology; Cancer research; Cell biology; Internal medicine; Medicine; Chemistry; Biochemistry; VEGF receptors","score_opus":0.017606415189029733,"score_gpt":0.25565083033336317,"score_spread":0.23804441514433344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2324783945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99300176,0.0023472402,0.002833703,0.00011244619,0.00004504198,0.000026429014,0.00026287456,0.00007983254,0.0012906259],"genre_scores_gemma":[0.991163,0.0011784132,0.0015859663,0.000058969028,0.000016768323,0.000032162206,0.00052215345,0.000037829577,0.005404683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987674,0.00002204893,0.000012122061,0.000021811577,0.000027266367,0.00003989957],"domain_scores_gemma":[0.99992764,0.000015833255,0.000012526664,0.000011775559,0.000011455683,0.000020786594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025427662,0.0002759876,0.00035077537,0.000274563,0.0001657068,0.0002167037,0.00022948941,0.00027310153,0.001424869],"category_scores_gemma":[0.00010985739,0.00016172674,0.00024451356,0.0001595143,0.00017171442,0.00015986252,0.00015478433,0.0006284533,0.0002546534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016753312,0.000044659926,0.000086731045,0.0000225975,0.000008359386,0.000027201515,0.00001794156,0.00011331664,0.99760324,0.00009895933,0.000053358697,0.0017561272],"study_design_scores_gemma":[0.000029738696,0.00044477827,0.0025142042,0.0000046329305,0.00002519242,0.00013427906,0.000015710772,0.0006271446,0.9936014,0.000026664282,0.0025733507,0.0000029280532],"about_ca_topic_score_codex":0.0018556355,"about_ca_topic_score_gemma":0.0023341463,"teacher_disagreement_score":0.0018556355,"about_ca_system_score_codex":0.00021177548,"about_ca_system_score_gemma":0.00024624952,"threshold_uncertainty_score":0.0047667027},"labels":[],"label_agreement":null},{"id":"W2325147559","doi":"10.1038/sj.gt.3301355","title":"HVJ-liposome-mediated transfection of HSVtk gene driven by AFP promoter inhibits hepatic tumor growth of hepatocellular carcinoma in SCID mice","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Japan Society for the Promotion of Science","keywords":"Suicide gene; Genetic enhancement; Transfection; Biology; Cancer research; Thymidine kinase; Viral vector; Hepatocellular carcinoma; Molecular biology; Virology; Gene; Virus","score_opus":0.012690218005393748,"score_gpt":0.24423230101780918,"score_spread":0.23154208301241544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2325147559","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941497,0.000988012,0.002739874,0.00013734802,0.000067752444,0.000024612276,0.0002700258,0.00015674047,0.001465963],"genre_scores_gemma":[0.9927037,0.00079439266,0.0012582004,0.000035478326,0.000025073805,0.00003973797,0.00061976374,0.000044469245,0.0044793244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997948,0.000032021093,0.00002308728,0.000030803287,0.00004448034,0.00007486173],"domain_scores_gemma":[0.99982554,0.000039885163,0.000034748635,0.000027459482,0.000016997976,0.000055285676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023560665,0.0004120906,0.00042993674,0.0005334345,0.00025713537,0.00030772487,0.00027374126,0.00031830437,0.0012879119],"category_scores_gemma":[0.00015852961,0.00022452167,0.00038680938,0.00030023168,0.00042158295,0.00039671623,0.00018649125,0.00079395156,0.0005642489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029398882,0.00005148892,0.00009030023,0.000025586525,0.000004637818,0.00003562848,0.000018516663,0.000050520488,0.9986865,0.00014398045,0.000039854847,0.0005590786],"study_design_scores_gemma":[0.000016026976,0.00018105391,0.000516675,0.0000015854531,0.000011947323,0.000056332647,0.000011410092,0.00046542432,0.9983341,0.00002297125,0.00037998747,0.000002477944],"about_ca_topic_score_codex":0.0017557908,"about_ca_topic_score_gemma":0.0013196686,"teacher_disagreement_score":0.0017557908,"about_ca_system_score_codex":0.0004096403,"about_ca_system_score_gemma":0.00041571326,"threshold_uncertainty_score":0.004308462},"labels":[],"label_agreement":null},{"id":"W2326394287","doi":"10.1038/sj.gt.3301534","title":"Immune-mediated destruction of transfected myocytes following DNA vaccination occurs via multiple mechanisms","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Medical Research Council Canada","keywords":"DNA vaccination; Biology; Immune system; Antigen; Immunology; Transfection; Major histocompatibility complex; Cell biology; Gene; Immunization; Genetics","score_opus":0.0104782399313062,"score_gpt":0.23409363795858723,"score_spread":0.22361539802728103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2326394287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8869875,0.0144459205,0.08583052,0.00069002464,0.0003685257,0.0005474643,0.00017030376,0.0005202912,0.010439565],"genre_scores_gemma":[0.9810978,0.0030214114,0.009103574,0.00022967323,0.00010088775,0.00027067875,0.000095865114,0.00005226725,0.0060278205],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903095,0.0002017149,0.00008812952,0.00019263616,0.0002455733,0.00024101556],"domain_scores_gemma":[0.9994355,0.0002138894,0.0001418126,0.00009060786,0.00007570757,0.000042505457],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010741098,0.0008162849,0.0010537254,0.00060764636,0.00028589,0.0008387731,0.0005133675,0.0011697498,0.001663335],"category_scores_gemma":[0.0005552065,0.00035920786,0.0008451097,0.00017055048,0.0005568078,0.0007497436,0.0007244294,0.0011433347,0.00068743277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015803523,0.00006815256,0.0002447539,0.00012161901,0.000024076488,0.00009691357,0.00004292667,0.00008106689,0.99300814,0.00091512944,0.000058303816,0.005180862],"study_design_scores_gemma":[0.00004240609,0.00048041993,0.0036260353,0.000025661937,0.000047783233,0.0004879413,0.00003347966,0.001184042,0.99193573,0.00033555468,0.0017903144,0.000010615687],"about_ca_topic_score_codex":0.00012935979,"about_ca_topic_score_gemma":0.00023794567,"teacher_disagreement_score":0.001663335,"about_ca_system_score_codex":0.00036954894,"about_ca_system_score_gemma":0.00020661388,"threshold_uncertainty_score":0.0056805015},"labels":[],"label_agreement":null},{"id":"W2326611690","doi":"10.1038/sj.gt.3301484","title":"Electrotransfer of naked DNA in the skeletal muscles of animal models of muscular dystrophies","year":2001,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"National Institutes of Health; Institut National de la Santé et de la Recherche Médicale","keywords":"Biology; Naked DNA; Muscular dystrophy; Genetic enhancement; DNA; Animal model; Anatomy; Virology; Computational biology; Genetics; Gene; Endocrinology","score_opus":0.015607422414599337,"score_gpt":0.24496224447826165,"score_spread":0.2293548220636623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2326611690","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9517077,0.006410568,0.03561155,0.00077319617,0.00044714392,0.00018099564,0.0004569124,0.00033582232,0.004076103],"genre_scores_gemma":[0.9537322,0.00536744,0.020137616,0.00019971652,0.000062553234,0.00019635039,0.0006941927,0.00013585393,0.019474175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99954826,0.00009140495,0.00004173103,0.00011856441,0.0001253872,0.00007474612],"domain_scores_gemma":[0.999694,0.000096607975,0.000077454024,0.00005682947,0.000024945315,0.00005024921],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000536894,0.0004209623,0.00055370224,0.00055249524,0.00028064757,0.00040736957,0.00043994607,0.0010769926,0.0011049039],"category_scores_gemma":[0.0004306669,0.00037624367,0.0003682084,0.00023387097,0.0007750449,0.00057946204,0.000407443,0.0011391541,0.00049283536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008279838,0.000017589127,0.000027872979,0.00005034136,0.0000067333963,0.000046937406,0.00002651162,0.000080693986,0.9982461,0.00035697286,0.000033944143,0.0010235016],"study_design_scores_gemma":[0.000036412155,0.000405848,0.00049162435,0.000019320838,0.00003494597,0.00025878966,0.000023425642,0.00056558184,0.994795,0.00013898936,0.0032242897,0.000005685144],"about_ca_topic_score_codex":0.000739844,"about_ca_topic_score_gemma":0.0011688938,"teacher_disagreement_score":0.0011049039,"about_ca_system_score_codex":0.0004254563,"about_ca_system_score_gemma":0.00028374023,"threshold_uncertainty_score":0.0036962032},"labels":[],"label_agreement":null},{"id":"W2329002519","doi":"10.1038/sj.gt.3301225","title":"Long-term tracking of murine hematopoietic cells transduced with a bicistronic retrovirus containing CD24 and EGFP genes","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Chugai Pharmaceutical; University of Toronto; F. Hoffmann-La Roche; Amgen","keywords":"Biology; Transgene; Haematopoiesis; Cistron; Transduction (biophysics); Genetic enhancement; Green fluorescent protein; Stem cell; Retrovirus; Molecular biology; Viral vector; Cell biology; Gene; Genetics","score_opus":0.017460552420938105,"score_gpt":0.27600072966677924,"score_spread":0.25854017724584116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2329002519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95427763,0.0027187052,0.037121587,0.00016598844,0.000109207045,0.00010198796,0.0012025918,0.00021160186,0.0040906393],"genre_scores_gemma":[0.964056,0.0008753097,0.022081666,0.00008170295,0.000023623852,0.00013220556,0.0015473579,0.00010552124,0.011096521],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99970776,0.000029378121,0.000023387169,0.000083021216,0.00008421409,0.00007222707],"domain_scores_gemma":[0.9995858,0.00010854704,0.000065925204,0.00008542875,0.0000868325,0.000067441535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043742865,0.0002573475,0.00044730245,0.00031009802,0.00037898583,0.0007330708,0.00047053903,0.00051931647,0.00069081626],"category_scores_gemma":[0.0001878379,0.00017139022,0.0003467562,0.00038734265,0.00024554547,0.00043080916,0.00040276445,0.0011495901,0.0005797998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009452665,0.00003139842,0.00028785857,0.000015253443,0.0000061243486,0.000029870886,0.000058035203,0.00010950382,0.9975926,0.00031828842,0.00004025801,0.0014162412],"study_design_scores_gemma":[0.000011879613,0.00013403405,0.0030722881,0.0000069845696,0.000025523166,0.00010086073,0.000040512066,0.0025765197,0.9920325,0.000068742425,0.0019250032,0.000005178299],"about_ca_topic_score_codex":0.0013099848,"about_ca_topic_score_gemma":0.0020660344,"teacher_disagreement_score":0.0013099848,"about_ca_system_score_codex":0.00047975752,"about_ca_system_score_gemma":0.00023632614,"threshold_uncertainty_score":0.0034809113},"labels":[],"label_agreement":null},{"id":"W2329662932","doi":"10.1038/sj.gt.3301189","title":"A combination of poloxamers increases gene expression of plasmid DNA in skeletal muscle","year":2000,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":212,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Supratek Pharma (Canada)","funders":"","keywords":"Poloxamer; Plasmid; Gene expression; Molecular biology; Genetic enhancement; Gene; Biology; DNA; Reporter gene; Naked DNA; Chemistry; Biochemistry; Polymer; Copolymer","score_opus":0.009362644301803068,"score_gpt":0.2389617349712006,"score_spread":0.22959909066939754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2329662932","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9775065,0.003917266,0.013632039,0.00027519913,0.00025131783,0.000118598604,0.00022783258,0.0002889455,0.0037822544],"genre_scores_gemma":[0.9831381,0.0014597545,0.0076906164,0.000109844856,0.000103081795,0.00013199498,0.0002958128,0.00009908005,0.0069717513],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994236,0.000089866095,0.000051048475,0.00017289433,0.00013817174,0.00012443743],"domain_scores_gemma":[0.99960977,0.0001420996,0.000072015246,0.00003750846,0.000029137247,0.00010943398],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046606662,0.00070203625,0.0007671794,0.00069077185,0.00025605623,0.00055257394,0.00036213463,0.0006901188,0.0020142712],"category_scores_gemma":[0.0003322221,0.00043193361,0.0005161999,0.000377533,0.0004098229,0.000458886,0.00042628834,0.0010079234,0.00044122708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030970518,0.00006963999,0.00007986381,0.00003958529,0.000008607509,0.000035308556,0.000011001332,0.000062994695,0.9976078,0.000098012286,0.000037851052,0.0016396923],"study_design_scores_gemma":[0.00003722311,0.0007459683,0.00050468027,0.000004549635,0.000025558564,0.000111294845,0.0000079042675,0.0003257449,0.9974809,0.000022607619,0.0007303939,0.0000031750972],"about_ca_topic_score_codex":0.00050731684,"about_ca_topic_score_gemma":0.0010996877,"teacher_disagreement_score":0.0020142712,"about_ca_system_score_codex":0.00036310306,"about_ca_system_score_gemma":0.00040453914,"threshold_uncertainty_score":0.0067384243},"labels":[],"label_agreement":null},{"id":"W2340356391","doi":"10.1038/gt.2016.36","title":"Development of an AAV9 coding for a 3XFLAG-TALEfrat#8-VP64 able to increase in vivo the human frataxin in YG8R mice","year":2016,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Biology; Frataxin; In vivo; Transcription (linguistics); Molecular biology; Gene; Effector; Haploinsufficiency; Gene expression; Messenger RNA; Activator (genetics); Transcription activator-like effector nuclease; Cell biology; Genetics; Genome editing; CRISPR; Iron-binding proteins","score_opus":0.014019029171785163,"score_gpt":0.3076732432123441,"score_spread":0.29365421404055897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2340356391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92872036,0.0012331976,0.06413168,0.0003114945,0.00018888232,0.00047304144,0.0016241716,0.0008852285,0.0024320032],"genre_scores_gemma":[0.9034698,0.0014578564,0.075663865,0.00013889268,0.000052630006,0.00056090776,0.00328822,0.00030798308,0.015059717],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99972314,0.000034194956,0.000038244634,0.00008556843,0.000077457094,0.00004137093],"domain_scores_gemma":[0.999814,0.000027375127,0.00008001737,0.000017780629,0.000016091502,0.000044771274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030873783,0.0006460318,0.00031768047,0.00051359506,0.0001871532,0.00028702532,0.0004615654,0.0006799511,0.0019294884],"category_scores_gemma":[0.00013741503,0.0003231098,0.00048927125,0.00013256593,0.00037984,0.0003141521,0.00030475215,0.0010116869,0.0008123183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025503967,0.000022365843,0.000038933806,0.000020304467,0.0000040016544,0.00004981747,0.000012158266,0.000052918673,0.99889994,0.00013408506,0.000023281164,0.00071663345],"study_design_scores_gemma":[0.000055152963,0.00049287966,0.0011075118,0.000012881651,0.000027061926,0.0005970813,0.000017507837,0.0011083164,0.9906701,0.00005883165,0.0058434173,0.0000093377175],"about_ca_topic_score_codex":0.00054052944,"about_ca_topic_score_gemma":0.00050840457,"teacher_disagreement_score":0.0019294884,"about_ca_system_score_codex":0.0002972548,"about_ca_system_score_gemma":0.00025594153,"threshold_uncertainty_score":0.006454766},"labels":[],"label_agreement":null},{"id":"W2342811791","doi":"10.1038/gt.2016.43","title":"Cardiac gene therapy: are we there yet?","year":2016,"lang":"en","type":"review","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Genetic enhancement; Gene delivery; Disease; Bioinformatics; Medicine; Intensive care medicine; Gene; Neuroscience; Biology; Pathology; Genetics","score_opus":0.05509808800875109,"score_gpt":0.31999536580102256,"score_spread":0.26489727779227146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2342811791","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006233809,0.9973579,0.0003224405,0.0008595855,0.000476685,0.0000031515203,0.000008962379,0.000010786235,0.00089804066],"genre_scores_gemma":[0.00055246,0.9972583,0.00040088576,0.00063973025,0.00043638254,0.000006806013,0.000014813082,0.0000030641258,0.0006875958],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997867,0.0000395718,0.000028311724,0.000034303936,0.00008369397,0.000027403661],"domain_scores_gemma":[0.99951637,0.00027848585,0.000048482096,0.000014439356,0.000087269684,0.000055013486],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010909348,0.000870659,0.0018854118,0.0011190994,0.0003410825,0.0014992829,0.0012285431,0.0019015778,0.0034892953],"category_scores_gemma":[0.0010694023,0.00025264447,0.00038449364,0.0011905183,0.001066987,0.0019869513,0.00067664357,0.0031353647,0.0018654197],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009514772,0.00007838986,0.00012628693,0.010017232,0.00004862405,0.00021572545,0.000059791324,0.00026482073,0.0025293336,0.006932288,0.054509632,0.92512274],"study_design_scores_gemma":[0.00002762382,0.000076083146,0.000256622,0.002382474,0.00008845888,0.0011595421,0.00006434612,0.00011657658,0.00061022834,0.0036909385,0.99150556,0.00002158532],"about_ca_topic_score_codex":0.000650336,"about_ca_topic_score_gemma":0.002166634,"teacher_disagreement_score":0.0034892953,"about_ca_system_score_codex":0.000621964,"about_ca_system_score_gemma":0.0010935512,"threshold_uncertainty_score":0.011672795},"labels":[],"label_agreement":null},{"id":"W2397582842","doi":"10.1038/gt.2016.18","title":"Intravesical treatment of advanced urothelial bladder cancers with oncolytic HSV-1 co-regulated by differentially expressed microRNAs","year":2016,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Oncolytic virus; microRNA; Herpes simplex virus; Oncolytic adenovirus; Bladder cancer; Cancer research; Urothelium; Genetic enhancement; Cancer; Biology; Virus; Medicine; Immunology; Urinary system; Gene; Internal medicine","score_opus":0.011996731715642967,"score_gpt":0.280383707637196,"score_spread":0.26838697592155303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2397582842","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99310726,0.0037809736,0.001855125,0.00007880346,0.00011342136,0.00006220267,0.000070081085,0.000057224872,0.00087490026],"genre_scores_gemma":[0.9960736,0.00115042,0.0016456386,0.000021375794,0.000014101562,0.00003234375,0.0000699784,0.000012346585,0.0009802581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983156,0.000029479628,0.000010957216,0.00002946178,0.000030824758,0.0000675987],"domain_scores_gemma":[0.9999454,0.000011530607,0.00001227827,0.000010424091,0.000007895111,0.000012493267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024809758,0.00027474813,0.0005470677,0.00023296275,0.00021437531,0.00040494907,0.00024762095,0.00031801438,0.00069237605],"category_scores_gemma":[0.00018745572,0.00017317585,0.00043807604,0.00022855199,0.0002390182,0.00031470667,0.00021546344,0.0005764293,0.0001154056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010671577,0.00037991392,0.00041170223,0.0001310415,0.000034717308,0.000096180076,0.000072031144,0.00048023995,0.9837853,0.00044969862,0.00013758855,0.012954422],"study_design_scores_gemma":[0.00011730441,0.0025785184,0.002169966,0.00000869826,0.00009268646,0.00021918816,0.000036008063,0.0018464854,0.9904067,0.000054492077,0.0024599622,0.000009900575],"about_ca_topic_score_codex":0.0012701282,"about_ca_topic_score_gemma":0.0017661202,"teacher_disagreement_score":0.0012701282,"about_ca_system_score_codex":0.00037134223,"about_ca_system_score_gemma":0.0004990106,"threshold_uncertainty_score":0.0026942492},"labels":[],"label_agreement":null},{"id":"W2414802120","doi":"10.1038/sj.gt.3301712","title":"Intratumoral administration of an adenovirus expressing a kinase dead form of ErbB-2 inhibits tumor growth","year":2002,"lang":"en","type":"article","venue":"Gene Therapy","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; Breast Cancer Society of Canada","keywords":"Immune system; Cancer research; Biology; ErbB; Receptor; Immunology","score_opus":0.07684677624089369,"score_gpt":0.3485078335019935,"score_spread":0.2716610572610998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414802120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.985261,0.0035996768,0.004573546,0.00038449754,0.00033954027,0.00008769093,0.000427746,0.0003260019,0.0050002905],"genre_scores_gemma":[0.9899018,0.0014742938,0.0021723965,0.000055008848,0.0000461577,0.000051632236,0.00056415267,0.000038383987,0.005696243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997522,0.000032876076,0.000012318704,0.000037830898,0.000045511777,0.00011920964],"domain_scores_gemma":[0.99978834,0.00008449376,0.000025790825,0.000039019636,0.000013514734,0.000048969698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035112564,0.0008048606,0.00064715336,0.0007573843,0.00035146842,0.00054756383,0.00044837242,0.0006215077,0.0015937763],"category_scores_gemma":[0.00019969333,0.00030113984,0.00045814714,0.00050387776,0.0005966884,0.00049239094,0.00018524783,0.0013540128,0.00049640465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012949674,0.0006829545,0.0001935872,0.000059848935,0.000022824388,0.00008158923,0.000032798078,0.00039616853,0.99145496,0.0005837148,0.00034486962,0.0048517883],"study_design_scores_gemma":[0.00017384271,0.0018654185,0.0008694793,0.000005222555,0.000039477352,0.00019018305,0.000028413002,0.0022911357,0.9927523,0.00008527303,0.001692522,0.0000066570274],"about_ca_topic_score_codex":0.003711034,"about_ca_topic_score_gemma":0.0037694585,"teacher_disagreement_score":0.003711034,"about_ca_system_score_codex":0.00080320827,"about_ca_system_score_gemma":0.0008348882,"threshold_uncertainty_score":0.007378876},"labels":[],"label_agreement":null},{"id":"W2533988460","doi":"10.1038/gt.2016.70","title":"Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy","year":2016,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"Oncolytics Biotech; National Institute for Health and Care Research; National Cancer Institute; National Institutes of Health; Cancer Research UK; University of Minnesota; Rosetrees Trust; Mayo Foundation for Medical Education and Research","keywords":"Oncolytic virus; Vesicular stomatitis virus; Blockade; Immune system; Priming (agriculture); Biology; CD8; Immunology; Combination therapy; Cancer research; Virology; Antigen; Virus; Melanoma; Immune checkpoint; Immunotherapy; Receptor; Pharmacology","score_opus":0.03414254946724767,"score_gpt":0.3196210101657175,"score_spread":0.2854784606984698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2533988460","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98174816,0.004990692,0.009119369,0.00024331885,0.00030577433,0.00015602852,0.00023771753,0.00056204107,0.002636825],"genre_scores_gemma":[0.9913083,0.001381428,0.004101619,0.00005613248,0.0000564208,0.00006140338,0.00019133456,0.00007331704,0.0027700812],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998147,0.000023346347,0.000009004408,0.00004938808,0.000044152162,0.00005944814],"domain_scores_gemma":[0.99987864,0.000032324355,0.000022780383,0.000025847796,0.000010090481,0.000030302943],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025008112,0.000587011,0.0008202982,0.00037337912,0.00017627137,0.0007505282,0.00044946428,0.0005403336,0.0022347036],"category_scores_gemma":[0.00031337136,0.0002705542,0.00040457194,0.00026185907,0.00034022835,0.0006530589,0.0002894455,0.0016401198,0.00048472895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00227551,0.0010657567,0.00043579345,0.00010001822,0.000042970845,0.000043376855,0.000044692537,0.0011897569,0.96131027,0.00079055195,0.0004691255,0.032232005],"study_design_scores_gemma":[0.00030133646,0.003469202,0.0020638644,0.0000131744055,0.00012393437,0.0002779997,0.000022219061,0.003407862,0.98643965,0.00026485158,0.003602811,0.0000130075905],"about_ca_topic_score_codex":0.0007485938,"about_ca_topic_score_gemma":0.0010096635,"teacher_disagreement_score":0.0022347036,"about_ca_system_score_codex":0.0004471852,"about_ca_system_score_gemma":0.0005952757,"threshold_uncertainty_score":0.0074757934},"labels":[],"label_agreement":null},{"id":"W255347894","doi":"10.1038/gt.2015.38","title":"Neutralizing circulating ghrelin by expressing a growth hormone secretagogue receptor-based protein protects against high-fat diet-induced obesity in mice","year":2015,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Ghrelin; Internal medicine; Endocrinology; Growth hormone secretagogue receptor; Adipose tissue; Secretagogue; Appetite; Biology; Receptor; Weight gain; Insulin; Thermogenin; Hormone; White adipose tissue; Medicine","score_opus":0.05253816444654541,"score_gpt":0.26065194367249916,"score_spread":0.20811377922595375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W255347894","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9878336,0.0013495318,0.00687999,0.0011075133,0.0004363666,0.00010017526,0.0005068871,0.00050840847,0.0012774727],"genre_scores_gemma":[0.9775227,0.00238639,0.010485236,0.00055279525,0.00020158479,0.00024791193,0.0010817742,0.00022289285,0.0072987634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99966025,0.00004592412,0.000026025044,0.00008007537,0.00007217793,0.00011554311],"domain_scores_gemma":[0.99974424,0.000031426407,0.0000883936,0.000027613623,0.000019537436,0.000088710374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004550538,0.0009303533,0.00074595754,0.0006883417,0.00029081694,0.0004998292,0.0005889121,0.00095087674,0.0016544076],"category_scores_gemma":[0.00023265576,0.00042597653,0.00065199455,0.00027291282,0.0011506923,0.0005406085,0.00023286218,0.0024124759,0.0004698036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009794608,0.0003063956,0.00006218343,0.00003668637,0.000016958147,0.000033222488,0.000017197655,0.00012124869,0.9967733,0.00024146964,0.00012605729,0.0012857795],"study_design_scores_gemma":[0.0005875017,0.002972077,0.0014614371,0.00001508699,0.00010770834,0.00014970046,0.000058472397,0.0022349,0.9896835,0.00020777172,0.0025039273,0.000017854856],"about_ca_topic_score_codex":0.0007202084,"about_ca_topic_score_gemma":0.0011303525,"teacher_disagreement_score":0.0016544076,"about_ca_system_score_codex":0.0005103311,"about_ca_system_score_gemma":0.0005274686,"threshold_uncertainty_score":0.0055345893},"labels":[],"label_agreement":null},{"id":"W2561412303","doi":"10.1038/gt.2016.89","title":"Deletion of the GAA repeats from the human frataxin gene using the CRISPR-Cas9 system in YG8R-derived cells and mouse models of Friedreich ataxia","year":2016,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Frataxin; CRISPR; Biology; Ataxia; Gene; Cas9; Genetics; Intron; Cell biology; Molecular biology; Iron-binding proteins; Neuroscience","score_opus":0.06619763214628806,"score_gpt":0.2733005128907394,"score_spread":0.20710288074445138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2561412303","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9566309,0.0014033221,0.030810041,0.00046639956,0.00026329322,0.00045064112,0.0031883176,0.0010648787,0.0057223137],"genre_scores_gemma":[0.9563546,0.0011788938,0.023787607,0.00009358868,0.000023758867,0.00033962794,0.0025061732,0.00022268905,0.015493143],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961346,0.00004489868,0.0000644384,0.00010174602,0.000110187146,0.00006518593],"domain_scores_gemma":[0.9998398,0.000018795208,0.000059960374,0.000028014343,0.000012914803,0.000040614075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003380347,0.0005819541,0.0005322884,0.0008268389,0.0004270025,0.00050736807,0.00076215697,0.0011975358,0.00225238],"category_scores_gemma":[0.00018493299,0.00038513154,0.00062163745,0.00033982104,0.00066362746,0.00037654527,0.00037307118,0.0013592292,0.0011277506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008000046,0.00004053917,0.00006856585,0.000029419185,0.000011504086,0.00018154953,0.0000384774,0.00013440721,0.99761224,0.00054279016,0.00012246988,0.0011379936],"study_design_scores_gemma":[0.000060878952,0.00016246732,0.0010342727,0.000013183322,0.000044579425,0.0010310493,0.000032382373,0.0013778865,0.9889503,0.00013712664,0.0071421363,0.000013776414],"about_ca_topic_score_codex":0.0017090972,"about_ca_topic_score_gemma":0.003265569,"teacher_disagreement_score":0.00225238,"about_ca_system_score_codex":0.00060840143,"about_ca_system_score_gemma":0.0006535,"threshold_uncertainty_score":0.007534921},"labels":[],"label_agreement":null},{"id":"W2789854767","doi":"10.1038/s41434-018-0012-0","title":"AAV-mediated NT-3 overexpression protects cochleae against noise-induced synaptopathy","year":2018,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Key Research and Development Program of China; Canadian Institutes of Health Research; Science and Technology Commission of Shanghai Municipality; Shanghai Municipal Education Commission","keywords":"Spiral ganglion; Cochlea; Synapse; Biology; Cell biology; Neuroscience; Ribbon synapse; Transgene; Hair cell; Neurotrophin-3; Gene; Neurotrophic factors; Brain-derived neurotrophic factor; Receptor; Genetics","score_opus":0.05500224520509105,"score_gpt":0.2921151061936123,"score_spread":0.23711286098852125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2789854767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943638,0.0005882962,0.0040933467,0.00006788702,0.000046709,0.00002586781,0.0001256847,0.00011455658,0.00057398266],"genre_scores_gemma":[0.9941379,0.0006211234,0.0026305802,0.000036297297,0.000010921563,0.00003099424,0.00020501783,0.000029247472,0.002297917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982977,0.000016413647,0.000024979272,0.000040995998,0.00004609647,0.000041672778],"domain_scores_gemma":[0.9998192,0.00003244996,0.000050541774,0.000023039476,0.00002185571,0.00005293132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017310717,0.00034581206,0.00036610043,0.00030333092,0.00016955863,0.00030681645,0.00023937147,0.00045744807,0.0008570905],"category_scores_gemma":[0.00017600619,0.00016865821,0.00028980197,0.00010029155,0.00039375405,0.00027293962,0.00027578455,0.0006121073,0.00026321525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003974916,0.000013811372,0.00003703383,0.000011256872,0.0000019598426,0.000027978582,0.000010435428,0.000022711483,0.9994437,0.00004738886,0.0000067864094,0.00033722696],"study_design_scores_gemma":[0.00001809561,0.00041453095,0.0018956895,0.000007265191,0.00001946544,0.00020214728,0.000034042485,0.0007697909,0.9957183,0.00007277448,0.00084282114,0.000005164611],"about_ca_topic_score_codex":0.000837295,"about_ca_topic_score_gemma":0.0009575913,"teacher_disagreement_score":0.0008570905,"about_ca_system_score_codex":0.00021874205,"about_ca_system_score_gemma":0.00034748157,"threshold_uncertainty_score":0.0028672218},"labels":[],"label_agreement":null},{"id":"W2801121431","doi":"10.1038/s41434-018-0018-7","title":"Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice","year":2018,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Dental and Craniofacial Research","keywords":"Hyperalgesia; Nerve growth factor; Allodynia; Neuropathic pain; Pharmacology; Biology; Calcium in biology; Tropomyosin receptor kinase A; Neurite; Endocrinology; Nociception; Internal medicine; Cell biology; Receptor; Medicine; Intracellular; Biochemistry; In vitro","score_opus":0.029555140807405397,"score_gpt":0.27873537048609015,"score_spread":0.24918022967868475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801121431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98881847,0.001673004,0.0056426288,0.00051373115,0.00017917775,0.00007916681,0.00054210785,0.0003576114,0.0021941855],"genre_scores_gemma":[0.98223996,0.0010301636,0.0048822225,0.00013840524,0.000069864516,0.00015105207,0.0006149839,0.00010826123,0.0107649425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949324,0.000068051166,0.000038265203,0.00010892854,0.00013490254,0.00015669472],"domain_scores_gemma":[0.99968815,0.000043443455,0.00011203301,0.000031150197,0.000023371616,0.000101938844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038403607,0.0006675794,0.00048015965,0.0007504348,0.00026081307,0.00045306413,0.00055687653,0.00084526074,0.0021437143],"category_scores_gemma":[0.00018130915,0.0003014179,0.00053224375,0.00021004284,0.0008549425,0.00052782946,0.00021316216,0.001667187,0.00046136678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022648888,0.00006516929,0.000042261447,0.000017829821,0.0000057886778,0.000034991222,0.000011898297,0.0000594252,0.9985448,0.00019444864,0.000054144894,0.00074269786],"study_design_scores_gemma":[0.00012613613,0.0011345606,0.0010987109,0.000009793021,0.000028724113,0.00018361484,0.000028835408,0.001125095,0.9940844,0.00009527067,0.00207689,0.000008016023],"about_ca_topic_score_codex":0.0014156725,"about_ca_topic_score_gemma":0.0026621632,"teacher_disagreement_score":0.0021437143,"about_ca_system_score_codex":0.0005864992,"about_ca_system_score_gemma":0.00053304003,"threshold_uncertainty_score":0.007171452},"labels":[],"label_agreement":null},{"id":"W2893974408","doi":"10.1038/s41434-018-0043-6","title":"Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials","year":2018,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; University of British Columbia; Government of Canada; BC Children's Hospital","keywords":"Aniridia; PAX6; Biology; Phenotype; Cornea; Epistasis; Allele; Inbred strain; Genetics; Mutation; Gene; Neuroscience","score_opus":0.06308256844785795,"score_gpt":0.3101481617641564,"score_spread":0.24706559331629843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2893974408","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90700275,0.003215513,0.08086359,0.00080871524,0.00016727064,0.0004897195,0.0015495416,0.00069899054,0.005203957],"genre_scores_gemma":[0.93920743,0.0030818763,0.04980886,0.00039852443,0.00006804636,0.0011953338,0.0016190335,0.00033001503,0.004290945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983437,0.00052276545,0.00014608471,0.00028520665,0.00057036185,0.00013198383],"domain_scores_gemma":[0.9991959,0.00022895954,0.00021512409,0.00016094881,0.00006491661,0.00013421549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014252275,0.0008067845,0.0006490651,0.0011799594,0.0003686938,0.00068089267,0.0005655128,0.0005051454,0.00272009],"category_scores_gemma":[0.0005674052,0.00026709368,0.00041478855,0.00040191336,0.00071255944,0.0005236736,0.00084374106,0.0018897059,0.00034576163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003274787,0.00011661956,0.0005163727,0.00006410042,0.000034149973,0.00012133039,0.00003475574,0.00013449212,0.9934151,0.0011463024,0.00010300133,0.003986343],"study_design_scores_gemma":[0.00018870972,0.0038024755,0.015725218,0.0000705853,0.0002786798,0.0022026745,0.00014016748,0.003204313,0.95837504,0.0018968541,0.01406012,0.000055160577],"about_ca_topic_score_codex":0.0003085798,"about_ca_topic_score_gemma":0.0009424638,"teacher_disagreement_score":0.00272009,"about_ca_system_score_codex":0.00035582413,"about_ca_system_score_gemma":0.0002773429,"threshold_uncertainty_score":0.009099603},"labels":[],"label_agreement":null},{"id":"W2921499526","doi":"10.1038/s41434-019-0067-6","title":"A novel approach for assessment of prostate cancer aggressiveness using survivin-driven tumour-activatable minicircles","year":2019,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Robarts Clinical Trials; Western University","funders":"Prostate Cancer Canada; Movember Foundation","keywords":"Prostate cancer; Minicircle; Survivin; Reporter gene; Cancer research; Cancer; Biology; Prostate; Gene; Gene expression; Genetics","score_opus":0.0596797864841448,"score_gpt":0.36523764263141806,"score_spread":0.30555785614727327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921499526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6374849,0.010157497,0.34436512,0.00030717332,0.00025390595,0.0005737675,0.0010530428,0.0012905141,0.0045140297],"genre_scores_gemma":[0.878611,0.004266139,0.10827662,0.0001468895,0.00005418946,0.0004640756,0.0011799758,0.00009963013,0.006901536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996636,0.000056652152,0.000023033757,0.0000954527,0.00010869887,0.000052600895],"domain_scores_gemma":[0.9997147,0.00008336486,0.00007050861,0.0000334872,0.000053610922,0.000044286226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047250048,0.00074565085,0.00038657276,0.0010075773,0.00025785813,0.0005822964,0.00034228904,0.000595585,0.0008145626],"category_scores_gemma":[0.00031716024,0.00033019081,0.00025988894,0.00039049887,0.00038983457,0.00045317234,0.00028020667,0.0015071909,0.0003094247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031544936,0.000020995749,0.00014439163,0.000026817836,0.0000054418724,0.000009319011,0.000018037883,0.000029817622,0.9974952,0.00009085691,0.000028069922,0.0020995631],"study_design_scores_gemma":[0.00000865938,0.00028340277,0.0017798813,0.000004533408,0.000034680987,0.0001653575,0.000019194313,0.0015197867,0.9946155,0.000063124295,0.0014938999,0.000011958004],"about_ca_topic_score_codex":0.0010536928,"about_ca_topic_score_gemma":0.0018238975,"teacher_disagreement_score":0.0010536928,"about_ca_system_score_codex":0.00040065768,"about_ca_system_score_gemma":0.00033942814,"threshold_uncertainty_score":0.0029070377},"labels":[],"label_agreement":null},{"id":"W2960706662","doi":"10.1038/s41434-019-0091-6","title":"A next-generation sequencing method for gene doping detection that distinguishes low levels of plasmid DNA against a background of genomic DNA","year":2019,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Biology; Plasmid; DNA sequencing; DNA; genomic DNA; Gene; Genetics; Sequencing by ligation; Computational biology; DNA nanoball sequencing; Molecular biology; Genomic library; Virology; Base sequence","score_opus":0.060769216193680455,"score_gpt":0.3143895871252087,"score_spread":0.2536203709315282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2960706662","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.100281104,0.001804047,0.88825,0.00034389016,0.00025778115,0.0003854104,0.0017165958,0.002732302,0.004228929],"genre_scores_gemma":[0.15468918,0.0020539574,0.82960767,0.0008345938,0.000062919455,0.00096945727,0.002760243,0.00032577637,0.008696273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984725,0.00041778391,0.00007986567,0.00044274374,0.00050602737,0.00008112677],"domain_scores_gemma":[0.9986374,0.0005892142,0.00029733073,0.0001896648,0.00018946719,0.00009686409],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011102369,0.0009564939,0.00074545544,0.0015219388,0.00054040627,0.00052719313,0.0005322532,0.0016872904,0.0018460837],"category_scores_gemma":[0.0021970524,0.00053220725,0.000626639,0.0007040848,0.0006122829,0.0006023403,0.00052938156,0.0015470078,0.0016141044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019524605,0.000028599747,0.00028849018,0.0000666971,0.000013656355,0.00002681844,0.000032263288,0.00008021924,0.99256986,0.00025929435,0.00015939021,0.006455175],"study_design_scores_gemma":[0.000012490819,0.00023589135,0.0025487836,0.000025043793,0.000050184906,0.00046128372,0.000023315191,0.0039523817,0.9843738,0.0004234122,0.007862643,0.00003083899],"about_ca_topic_score_codex":0.0004989445,"about_ca_topic_score_gemma":0.0018406379,"teacher_disagreement_score":0.0018460837,"about_ca_system_score_codex":0.00040721797,"about_ca_system_score_gemma":0.00069421483,"threshold_uncertainty_score":0.0061757565},"labels":[],"label_agreement":null},{"id":"W3031070702","doi":"10.1038/s41434-020-0156-6","title":"Optimization of antisense-mediated exon skipping for Duchenne muscular dystrophy","year":2020,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Muscular Dystrophy Canada; University of Alberta; Government of Canada","keywords":"Exon skipping; Duchenne muscular dystrophy; Exon; Dystrophin; Muscular dystrophy; Medicine; Bioinformatics; Biology; Genetics; Gene; Alternative splicing","score_opus":0.0315453696254749,"score_gpt":0.30112002282080785,"score_spread":0.26957465319533297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3031070702","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006253175,0.9965501,0.0012403926,0.00012099516,0.00019031436,0.0000099114495,0.000025978712,0.000020632191,0.0012163797],"genre_scores_gemma":[0.0038568734,0.9931814,0.0011432128,0.00020023988,0.000104784354,0.000020415042,0.00008115871,0.0000062556855,0.0014056354],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998543,0.000024024937,0.000017065144,0.000028029823,0.000056867375,0.00001967009],"domain_scores_gemma":[0.9999157,0.00004073932,0.00001649542,0.00000299265,0.00001637931,0.000007776777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049636344,0.0009520412,0.0011840853,0.0007816219,0.00014243498,0.0006350009,0.000728639,0.00080286124,0.001798309],"category_scores_gemma":[0.0003495299,0.0002447272,0.00047505758,0.00087148434,0.0003745324,0.0005033699,0.0004240624,0.001602864,0.0009912201],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019231882,0.00015780823,0.00011614419,0.008874594,0.00011469729,0.00028234386,0.00004114515,0.0013368122,0.022568299,0.0051270053,0.012844962,0.9483439],"study_design_scores_gemma":[0.000121833735,0.00054782274,0.001242037,0.0019359636,0.00031667607,0.0019607868,0.000039273298,0.00082376593,0.011157779,0.0029563857,0.9788423,0.000055388136],"about_ca_topic_score_codex":0.0006874094,"about_ca_topic_score_gemma":0.001280782,"teacher_disagreement_score":0.001798309,"about_ca_system_score_codex":0.00044963526,"about_ca_system_score_gemma":0.0003563472,"threshold_uncertainty_score":0.006015897},"labels":[],"label_agreement":null},{"id":"W3092143815","doi":"10.1038/s41434-020-00198-7","title":"Engineered AAV8 capsid acquires heparin and AVB sepharose binding capacity but has altered in vivo transduction efficiency","year":2020,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Public Health Agency of Canada; University of Guelph","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Canadian Lung Association; Government of Canada","keywords":"Capsid; Transduction (biophysics); In vivo; Sepharose; Affinity chromatography; Biology; Heparan sulfate; Molecular biology; Recombinant DNA; Mutant; In vitro; Biochemistry; Heparin; Cell biology; Gene; Enzyme","score_opus":0.04673529924870008,"score_gpt":0.27501630499894636,"score_spread":0.2282810057502463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092143815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850026,0.00029991026,0.011889151,0.00013592969,0.00006937222,0.000032666896,0.00033864062,0.00040389638,0.0018277771],"genre_scores_gemma":[0.9839972,0.0001701239,0.008528704,0.000053815023,0.0000116864285,0.00002662998,0.00083608483,0.00020262065,0.0061731725],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999648,0.000053618955,0.00004004592,0.000062144754,0.00012167934,0.0000745905],"domain_scores_gemma":[0.99956745,0.000091518625,0.00012246544,0.0000750341,0.000052617863,0.00009087989],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003216358,0.00058813463,0.000362621,0.0002787848,0.00014610073,0.0005422834,0.00042410704,0.0005785989,0.0013840228],"category_scores_gemma":[0.00027208118,0.0002597034,0.00028419073,0.00017021988,0.00045578228,0.00034380783,0.00027295237,0.0009011526,0.0007233935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025072088,0.000015363194,0.000041868247,0.000008128762,0.0000024930255,0.000020913023,0.0000058164323,0.000027535172,0.9994103,0.00010327467,0.000013100508,0.00032627882],"study_design_scores_gemma":[0.0000053960907,0.00007062239,0.0005542406,0.0000015711894,0.0000054200946,0.0001589616,0.00000437558,0.00036969272,0.9977494,0.000025547211,0.0010508149,0.0000040358773],"about_ca_topic_score_codex":0.0009238837,"about_ca_topic_score_gemma":0.0007147742,"teacher_disagreement_score":0.0013840228,"about_ca_system_score_codex":0.000473267,"about_ca_system_score_gemma":0.0002826548,"threshold_uncertainty_score":0.004630029},"labels":[],"label_agreement":null},{"id":"W3129142660","doi":"10.1038/s41434-021-00227-z","title":"Human MiniPromoters for ocular-rAAV expression in ON bipolar, cone, corneal, endothelial, Müller glial, and PAX6 cells","year":2021,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; BC Children's Hospital; University of British Columbia","funders":"Health Canada; Québec Consortium for Drug Discovery; Weston Brain Institute; Government of Canada; Fondation Brain Canada","keywords":"PAX6; Genetic enhancement; Biology; Gene delivery; Muller glia; Retina; Promoter; Stroma; Gene; Molecular biology; Gene expression; Cancer research; Immunology; Stem cell; Cell biology; Genetics; Neuroscience; Immunohistochemistry; Transcription factor; Progenitor cell","score_opus":0.01463467848948813,"score_gpt":0.2950902394436656,"score_spread":0.28045556095417745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129142660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6971278,0.007784631,0.2688672,0.00037063347,0.00034008082,0.0019442489,0.008058822,0.004308561,0.01119803],"genre_scores_gemma":[0.6813457,0.0063331304,0.2386323,0.00045255813,0.00009825037,0.0015966122,0.02886809,0.001831445,0.040841974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996369,0.000056792363,0.000059630605,0.00009705087,0.00009732475,0.00005229798],"domain_scores_gemma":[0.999686,0.00006815354,0.00009485799,0.000056515655,0.000046905476,0.000047568174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004585681,0.0007689067,0.00044489387,0.0005526869,0.00030879906,0.00040459004,0.00044333213,0.0004134168,0.004765791],"category_scores_gemma":[0.0003910815,0.00044110845,0.0006417349,0.0003612469,0.00032313075,0.0004273256,0.00046949647,0.000829025,0.0025554127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012219712,0.000028503722,0.00019495095,0.00011830124,0.000009846969,0.00005510861,0.000051095223,0.00018884611,0.98923725,0.00038304774,0.00026321452,0.0093476875],"study_design_scores_gemma":[0.00003065526,0.00039567088,0.0009771378,0.00002831525,0.000051530773,0.00041901157,0.000026573674,0.00074304163,0.96970457,0.000099813304,0.027507043,0.000016563885],"about_ca_topic_score_codex":0.0003517009,"about_ca_topic_score_gemma":0.0009928808,"teacher_disagreement_score":0.004765791,"about_ca_system_score_codex":0.00037954008,"about_ca_system_score_gemma":0.00043118428,"threshold_uncertainty_score":0.01594311},"labels":[],"label_agreement":null},{"id":"W3131013716","doi":"10.1038/s41434-021-00236-y","title":"AAV-mediated delivery of actoxumab and bezlotoxumab results in serum and mucosal antibody concentrations that provide protection from C. difficile toxin challenge","year":2021,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Clostridium difficile toxin A; Clostridium difficile; Clostridium difficile toxin B; Microbiology; Antibiotics; Antibody; Monoclonal antibody; Enterotoxin; Toxin; Virology; Biology; Enterocolitis; Immunology; Medicine; Gene; Pathology; Escherichia coli","score_opus":0.04693519656594888,"score_gpt":0.2978495359796029,"score_spread":0.25091433941365404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3131013716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910166,0.0011719549,0.0040904214,0.00038401553,0.00018602746,0.00006571881,0.00032839982,0.00024062289,0.0025161093],"genre_scores_gemma":[0.9926709,0.00044502376,0.002465573,0.00009048805,0.000026259995,0.000035020854,0.0003080723,0.000023509963,0.003935119],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997193,0.00003205317,0.000019364697,0.000052065454,0.00007203488,0.00010525618],"domain_scores_gemma":[0.9998727,0.000018531216,0.000031781623,0.000011555923,0.000017301167,0.000048106995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023962493,0.0003756697,0.00033001052,0.00025550363,0.00022273148,0.00048018436,0.00017061879,0.00058156846,0.0016942951],"category_scores_gemma":[0.00019883513,0.00015665968,0.00028163934,0.00011883794,0.00043350278,0.00031076305,0.00012665718,0.0011352202,0.00037582926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011089628,0.00022680916,0.0002031633,0.000051866533,0.000013131133,0.000047146263,0.000027601645,0.0001616571,0.9928879,0.00027878588,0.00034171488,0.004651306],"study_design_scores_gemma":[0.00031526596,0.003952061,0.0046839993,0.0000154498,0.0000648417,0.00040849854,0.00006941812,0.0021564385,0.98355687,0.00012295396,0.004639783,0.00001439024],"about_ca_topic_score_codex":0.0017514651,"about_ca_topic_score_gemma":0.0024914166,"teacher_disagreement_score":0.0017514651,"about_ca_system_score_codex":0.0005789577,"about_ca_system_score_gemma":0.0005211247,"threshold_uncertainty_score":0.0056679845},"labels":[],"label_agreement":null},{"id":"W3164854901","doi":"10.1038/s41434-021-00261-x","title":"The transformative potential of HSC gene therapy as a genetic medicine","year":2021,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bombardier (Canada)","funders":"","keywords":"Genetic enhancement; Regenerative medicine; Stem cell; Biology; Haematopoiesis; Transplantation; Gene delivery; Cell therapy; Immune system; Commercialization; Genome editing; Hematopoietic stem cell; Transformative learning; Immunology; Viral vector; Gene; Genetics; Medicine; Genome; Internal medicine; Political science","score_opus":0.040223899314294986,"score_gpt":0.3657468997380648,"score_spread":0.3255230004237698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164854901","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009416412,0.99781597,0.00023101091,0.00020525932,0.00021661868,0.0000027798953,0.000013145637,0.0000056291196,0.001415448],"genre_scores_gemma":[0.00075231097,0.9978387,0.00029146113,0.00015817056,0.00014816737,0.0000051110305,0.000024284825,0.0000017718552,0.00078003586],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998894,0.000020112693,0.000009265449,0.000016894382,0.000049414855,0.000014868291],"domain_scores_gemma":[0.9998223,0.00010391965,0.000015476473,0.0000062712757,0.000036777787,0.000015226047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005044309,0.000832641,0.0010346564,0.0018096769,0.00022063329,0.0010392304,0.0006427195,0.0009854509,0.0026389381],"category_scores_gemma":[0.00047059893,0.00019633984,0.0003199348,0.0018291387,0.0005849754,0.0010287801,0.00054405275,0.0020640437,0.0016099227],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008728804,0.00008385655,0.00009490663,0.010067994,0.000047360387,0.0002611009,0.00005794067,0.0005355185,0.0059872936,0.018152924,0.030088538,0.93453526],"study_design_scores_gemma":[0.000014556755,0.000055784345,0.00021560822,0.0011134107,0.000041098996,0.0005773542,0.000027212072,0.00008605708,0.0011874076,0.0035066193,0.9931624,0.000012565245],"about_ca_topic_score_codex":0.0010100391,"about_ca_topic_score_gemma":0.0017257475,"teacher_disagreement_score":0.0026389381,"about_ca_system_score_codex":0.000662778,"about_ca_system_score_gemma":0.0008330973,"threshold_uncertainty_score":0.008828104},"labels":[],"label_agreement":null},{"id":"W3191050526","doi":"10.1038/s41434-021-00281-7","title":"XIAP gene therapy effects on retinal ganglion cell structure and function in a mouse model of glaucoma","year":2021,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Glaucoma Research Society of Canada","keywords":"XIAP; Retinal ganglion cell; Glaucoma; Optic nerve; Biology; Inhibitor of apoptosis; Neuroprotection; Programmed cell death; Neuroscience; Apoptosis; Caspase; Genetics","score_opus":0.00958121045722638,"score_gpt":0.2265853527542613,"score_spread":0.21700414229703494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3191050526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936799,0.0016018613,0.0017370586,0.00034094992,0.00009996144,0.000052488536,0.00051810476,0.00022390376,0.001745816],"genre_scores_gemma":[0.98767006,0.0012249739,0.0022241867,0.00012069858,0.000021448817,0.0000931488,0.00033721514,0.000071751456,0.008236491],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996921,0.000048715054,0.000038056765,0.00006591837,0.00008314717,0.00007210907],"domain_scores_gemma":[0.9995708,0.00008733939,0.00013487095,0.000050340044,0.000024216499,0.00013239872],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039321464,0.0006898676,0.00054331374,0.0017044101,0.00043409262,0.00047052422,0.00046631967,0.0011058479,0.0027779897],"category_scores_gemma":[0.00022721512,0.00041977534,0.00047670965,0.00045647143,0.0009860994,0.0006329155,0.00026213107,0.0016069785,0.0003357529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058028253,0.00019188784,0.0001421106,0.000033180244,0.000010017355,0.00018711037,0.000038809547,0.000116493226,0.997163,0.00035843658,0.000076153934,0.0011024362],"study_design_scores_gemma":[0.00016289503,0.0014728899,0.0021555445,0.000014301846,0.00006694844,0.0003907555,0.00007878313,0.001013475,0.993194,0.00018124121,0.001256328,0.0000129469145],"about_ca_topic_score_codex":0.0016104017,"about_ca_topic_score_gemma":0.001698061,"teacher_disagreement_score":0.0027779897,"about_ca_system_score_codex":0.000531045,"about_ca_system_score_gemma":0.00044534553,"threshold_uncertainty_score":0.009293318},"labels":[],"label_agreement":null},{"id":"W3195976193","doi":"10.1038/s41434-021-00288-0","title":"Novel design of nucleic acid standards for hydrolysis probe-based PCR with melting analysis","year":2021,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Department of Health and Aged Care, Australian Government; World Anti-Doping Agency","keywords":"Amplicon; Polymerase chain reaction; Biology; Nucleic acid; Nucleic acid thermodynamics; Chromatography; DNA; Computational biology; Molecular biology; Genetics; Chemistry; Gene; Base sequence","score_opus":0.018224386679537418,"score_gpt":0.27892315121717925,"score_spread":0.26069876453764185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195976193","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.054563075,0.00096258806,0.93903404,0.00031363012,0.00018664965,0.0009577406,0.00029675668,0.0021614572,0.0015241421],"genre_scores_gemma":[0.1067901,0.00070176204,0.8859662,0.0002995781,0.00006576893,0.0016002485,0.0012318387,0.00032853681,0.003016021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9955389,0.0008571876,0.0004219022,0.0014782553,0.0013959807,0.00030777018],"domain_scores_gemma":[0.99694437,0.0010908532,0.00052571076,0.00029410244,0.0009028204,0.00024210858],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0041271835,0.0018262672,0.0015657307,0.0015279497,0.0008046508,0.0013849727,0.0027316215,0.0021052363,0.0022514604],"category_scores_gemma":[0.004688355,0.0023512354,0.0010894954,0.0010548648,0.0013975417,0.0018458333,0.0011150286,0.0033792611,0.0026326918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009825952,0.00008674334,0.0001921855,0.00014515931,0.000013935778,0.00003957399,0.000071903225,0.00057155633,0.9862164,0.0014467381,0.0001872004,0.010930211],"study_design_scores_gemma":[0.00001655588,0.00019247411,0.00020596472,0.000013511574,0.000020951658,0.00010179409,0.000020656675,0.0052013258,0.9899003,0.00034026484,0.003958668,0.000027486645],"about_ca_topic_score_codex":0.00036695303,"about_ca_topic_score_gemma":0.0010500826,"teacher_disagreement_score":0.0041271835,"about_ca_system_score_codex":0.0011976092,"about_ca_system_score_gemma":0.0015585166,"threshold_uncertainty_score":0.021826923},"labels":[],"label_agreement":null},{"id":"W3203462303","doi":"10.1038/s41434-021-00295-1","title":"Long-term safety and efficacy of intramyocardial adenovirus-mediated VEGF-DΔNΔC gene therapy eight-year follow-up of phase I KAT301 study","year":2021,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Kuopion Yliopistollinen Sairaala","keywords":"Mace; Medicine; Hazard ratio; Internal medicine; Adverse effect; Genetic enhancement; Angina; Confidence interval; Incidence (geometry); Randomized controlled trial; Surgery; Myocardial infarction; Percutaneous coronary intervention; Biology","score_opus":0.03771391769886721,"score_gpt":0.33723897960194077,"score_spread":0.29952506190307354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203462303","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980108,0.0009485975,0.0003540749,0.000046120684,0.000016574257,0.00010386084,0.00018604583,0.000020947067,0.00031306],"genre_scores_gemma":[0.9983664,0.00038670274,0.00022384075,0.0001326205,0.000026637459,0.00010867258,0.00043412778,0.0000048359466,0.0003162488],"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","domain_scores_codex":[0.9996605,0.0001411893,0.000028567203,0.000052251402,0.00005179832,0.00006565962],"domain_scores_gemma":[0.9993166,0.00014146548,0.00020523246,0.000094352596,0.00006790094,0.00017443867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015916737,0.00041456503,0.0010471536,0.0001363111,0.00020081853,0.00039896258,0.0003045201,0.0005323295,0.00063195615],"category_scores_gemma":[0.0006844345,0.00013159325,0.0006320809,0.00012832925,0.00036021607,0.00031189065,0.00014681199,0.0008893306,0.00018388851],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.3753217,0.038953643,0.07183456,0.0008631647,0.0020962048,0.00081726856,0.0003188798,0.0027952755,0.29785332,0.0002453356,0.0021422638,0.20675842],"study_design_scores_gemma":[0.054042257,0.7646571,0.14748904,0.000045499528,0.0009003646,0.0007974271,0.00007896358,0.0019470153,0.027452221,0.00016436122,0.0023847597,0.0000410131],"about_ca_topic_score_codex":0.00022063329,"about_ca_topic_score_gemma":0.00032362496,"teacher_disagreement_score":0.0015916737,"about_ca_system_score_codex":0.00030435843,"about_ca_system_score_gemma":0.00033972872,"threshold_uncertainty_score":0.008417666},"labels":[],"label_agreement":null},{"id":"W3203868028","doi":"10.1038/s41434-021-00297-z","title":"CRISPR-SCReT (CRISPR-Stop Codon Read Through) method to control Cas9 expression for gene editing","year":2021,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Ataxia UK; Government of Canada; Ataxia Canada; National Ataxia Foundation","keywords":"CRISPR; Cas9; Biology; Gene; Exon; Genome editing; Stop codon; Plasmid; Molecular biology; Genetics; Nonsense mutation; Guide RNA; HEK 293 cells; Mutation; Missense mutation","score_opus":0.018984780308479828,"score_gpt":0.36636590565148996,"score_spread":0.34738112534301013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203868028","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16796505,0.0033427998,0.7750859,0.0010088803,0.0011500621,0.0020862126,0.006481831,0.01392553,0.028953657],"genre_scores_gemma":[0.45145693,0.002700978,0.4267675,0.0009150576,0.00008544877,0.0015545539,0.011394233,0.0021505812,0.10297464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895334,0.00011925987,0.000119122684,0.000307593,0.00038623583,0.00011450313],"domain_scores_gemma":[0.9997174,0.000050124505,0.00007350637,0.00006697518,0.00004641019,0.000045575038],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080066593,0.00080257136,0.0010767663,0.0010541641,0.00080865785,0.000750423,0.00088892266,0.0010903089,0.006388251],"category_scores_gemma":[0.0004707829,0.00051053305,0.0009256727,0.00078266347,0.00053863856,0.0004704875,0.0007324905,0.0024685946,0.0043833624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007120979,0.00005330998,0.000110575624,0.00016603261,0.000021535689,0.00015311476,0.000038450286,0.00016447414,0.9867458,0.0013153955,0.0015289219,0.009631186],"study_design_scores_gemma":[0.00002330271,0.000075822456,0.0004259786,0.000010735395,0.000034851346,0.0006275639,0.0000117994905,0.0015734867,0.972983,0.00019130658,0.024012832,0.000029302051],"about_ca_topic_score_codex":0.0009519841,"about_ca_topic_score_gemma":0.0024161004,"teacher_disagreement_score":0.006388251,"about_ca_system_score_codex":0.0006305015,"about_ca_system_score_gemma":0.0007477411,"threshold_uncertainty_score":0.021370828},"labels":[],"label_agreement":null},{"id":"W33531684","doi":"10.1038/s41434-021-00227-z","title":"The utility of peer group supervision for psychologists in practice.","year":2003,"lang":"en","type":"dissertation","venue":"Gene Therapy","topic":"Counseling Practices and Supervision","field":"Psychology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Québec Consortium for Drug Discovery; Weston Brain Institute; Government of Canada; Fondation Brain Canada","keywords":"Group (periodic table); Psychology; Peer group; Applied psychology; Social psychology; Chemistry","score_opus":0.058336750578017946,"score_gpt":0.4160632715570465,"score_spread":0.3577265209790285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W33531684","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01493223,0.0032507174,0.20759583,0.12938936,0.026717613,0.005654991,0.0008493062,0.012689022,0.59892094],"genre_scores_gemma":[0.34676465,0.0033654696,0.21914668,0.051530212,0.01013791,0.013111761,0.0012355965,0.006616651,0.34809107],"study_design_codex":"design_other","study_design_gemma":"qualitative","domain_scores_codex":[0.9419722,0.03654324,0.0021314581,0.0057144826,0.0111965155,0.0024421678],"domain_scores_gemma":[0.8183367,0.04203833,0.0074853934,0.03592437,0.05239926,0.04381594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.043240596,0.00092884,0.00083546474,0.0020041028,0.005057764,0.007707272,0.0034141222,0.0036632437,0.12996885],"category_scores_gemma":[0.1361809,0.00061752985,0.00058051455,0.0016054788,0.00663238,0.0067518163,0.014548118,0.006555623,0.06976634],"study_design_candidate":"qualitative","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020374844,0.00057250005,0.0026264177,0.00059875316,0.000049035236,0.0004216408,0.009514835,0.00033539717,0.0014136365,0.019309841,0.42065215,0.5443019],"study_design_scores_gemma":[0.00013861332,0.0002178802,0.0031349952,0.0006613474,0.00001674109,0.0004804167,0.0069645336,0.0008499387,0.00056977326,0.034445558,0.9524521,0.00006810048],"about_ca_topic_score_codex":0.0022731782,"about_ca_topic_score_gemma":0.0030845657,"teacher_disagreement_score":0.12996885,"about_ca_system_score_codex":0.0032736717,"about_ca_system_score_gemma":0.027556287,"threshold_uncertainty_score":0.43478912},"labels":[],"label_agreement":null},{"id":"W4207017208","doi":"10.1038/s41434-022-00316-7","title":"Antisense oligonucleotides as a potential treatment for brain deficits observed in myotonic dystrophy type 1","year":2022,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut Universitaire en Santé Mentale de Québec; Université Laval","funders":"U.S. Army Medical Research Acquisition Activity; Canadian Institutes of Health Research; AFM-Téléthon; Ionis Pharmaceuticals; French Muscular Dystrophy Association; Servier; Muscular Dystrophy Association; Government of Canada; U.S. Department of Defense","keywords":"Myotonic dystrophy; Myotonia; Systemic administration; Biology; Medicine; Atrophy; Neuroscience; Bioinformatics; Internal medicine; Endocrinology; In vivo; Genetics","score_opus":0.0727699569777682,"score_gpt":0.29633587463957667,"score_spread":0.22356591766180847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4207017208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9147958,0.063220605,0.010138678,0.0008730544,0.00065023726,0.0003327059,0.0005330236,0.0004446615,0.0090111485],"genre_scores_gemma":[0.9384887,0.045065872,0.00741775,0.000327712,0.00014933196,0.00027872258,0.00052650535,0.000024764522,0.007720625],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999689,0.0000057287357,0.0000034309128,0.0000093017425,0.0000065943514,0.00000612329],"domain_scores_gemma":[0.999985,0.0000029467888,0.0000045188776,9.0442205e-7,0.0000030773774,0.0000034858253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007380274,0.00029955237,0.00029905615,0.00026623308,0.000118301905,0.00013674318,0.00015899436,0.0002844214,0.0010259805],"category_scores_gemma":[0.00005567115,0.000052404168,0.00017256514,0.00013290715,0.00012884852,0.00010986357,0.00009221592,0.00042036417,0.00016304068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009464928,0.00028565625,0.00021847097,0.0005431686,0.00004636528,0.0003093757,0.00005505656,0.00029065958,0.9241818,0.0011700863,0.00077066675,0.07118219],"study_design_scores_gemma":[0.0012797336,0.018949391,0.0059797484,0.00020707202,0.00047926,0.0024390966,0.000117943775,0.00186461,0.8923317,0.00093967404,0.075357236,0.00005459736],"about_ca_topic_score_codex":0.00049276184,"about_ca_topic_score_gemma":0.0010900202,"teacher_disagreement_score":0.0010259805,"about_ca_system_score_codex":0.0001389682,"about_ca_system_score_gemma":0.00015658903,"threshold_uncertainty_score":0.0034322143},"labels":[],"label_agreement":null},{"id":"W4213096054","doi":"10.1038/s41434-022-00323-8","title":"CRISPR editing as a therapeutic strategy for Duchenne muscular dystrophy—anti-Cas9 immune response casts its shadow over safety and efficacy","year":2022,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"CRISPR; Duchenne muscular dystrophy; Genome editing; Biology; Genetic enhancement; Cas9; Immune system; Muscular dystrophy; Virology; Genetics; Bioinformatics; Immunology; Gene","score_opus":0.01482409384323293,"score_gpt":0.3080905154608623,"score_spread":0.2932664216176294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213096054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6347602,0.08979765,0.1921999,0.036441848,0.0026868975,0.00018569586,0.0006050699,0.0030268605,0.04029595],"genre_scores_gemma":[0.9602091,0.012342738,0.013557178,0.0018447214,0.00020794797,0.000027183198,0.00010282398,0.00012725238,0.011581049],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99936205,0.00013796745,0.000040300463,0.00011515393,0.00025881306,0.00008581401],"domain_scores_gemma":[0.99969256,0.00012006517,0.000060862087,0.000045370303,0.00003964309,0.000041497253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010189168,0.00035071882,0.00060615945,0.00035116012,0.0003984236,0.0011828059,0.0004339404,0.0009513516,0.0013301229],"category_scores_gemma":[0.00055696996,0.0001953183,0.00023050321,0.00013020926,0.0014320196,0.00060259213,0.00041921088,0.0020163993,0.00033614153],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004481912,0.00008210251,0.0003748054,0.00022094253,0.000048482863,0.0002683781,0.000084253355,0.0006661034,0.9262588,0.018644772,0.0023812486,0.05052191],"study_design_scores_gemma":[0.00010218255,0.0016945396,0.0032414915,0.00013811803,0.00013372567,0.00412621,0.00020743665,0.005913241,0.9047851,0.011994567,0.067583315,0.00008009806],"about_ca_topic_score_codex":0.0008348811,"about_ca_topic_score_gemma":0.0015300391,"teacher_disagreement_score":0.0013301229,"about_ca_system_score_codex":0.0006466876,"about_ca_system_score_gemma":0.00063160184,"threshold_uncertainty_score":0.005388558},"labels":[],"label_agreement":null},{"id":"W4224315490","doi":"10.1038/s41434-022-00338-1","title":"Central and peripheral delivered AAV9-SMN are both efficient but target different pathomechanisms in a mouse model of spinal muscular atrophy","year":2022,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Muscular Dystrophy Canada; Government of Canada; Muscular Dystrophy Association","keywords":"Spinal muscular atrophy; SMA*; SMN1; Biology; Neuroprotection; Peripheral; Peripheral nervous system; Central nervous system; Motor neuron; Genetic enhancement; Neuroscience; Pathology; Medicine; Spinal cord; Internal medicine; Disease; Gene","score_opus":0.02070848231510886,"score_gpt":0.2518619344652871,"score_spread":0.23115345215017824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224315490","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98475885,0.0014913942,0.007957717,0.00047419532,0.0002155278,0.00010083442,0.00084545667,0.0004078857,0.0037482455],"genre_scores_gemma":[0.969625,0.0009105999,0.010010448,0.00017996147,0.000033277178,0.00018011926,0.0007368389,0.00014336892,0.018180294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923325,0.00010510131,0.000069990405,0.00021983097,0.00020906139,0.00016270556],"domain_scores_gemma":[0.9996247,0.00004320087,0.00010633025,0.000034592056,0.00003302041,0.00015818853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005635902,0.0008582523,0.0006060113,0.0012710292,0.00039467908,0.0005148857,0.00064742105,0.0013873145,0.0030819348],"category_scores_gemma":[0.00018376231,0.00040044292,0.00060159474,0.00029230467,0.0012890336,0.0007043986,0.00040101015,0.0021360859,0.0005687431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035580216,0.00010084177,0.00010306121,0.000041730535,0.00000844485,0.00009011458,0.000025418229,0.00007075199,0.997727,0.00037882332,0.00008255566,0.0010156379],"study_design_scores_gemma":[0.00009697778,0.0016491986,0.0029884097,0.000028299683,0.00005994466,0.00070956076,0.00009807499,0.0015549671,0.9895948,0.00020697434,0.002995376,0.000017431952],"about_ca_topic_score_codex":0.0014429978,"about_ca_topic_score_gemma":0.0031494356,"teacher_disagreement_score":0.0030819348,"about_ca_system_score_codex":0.0005927611,"about_ca_system_score_gemma":0.0006024184,"threshold_uncertainty_score":0.010310113},"labels":[],"label_agreement":null},{"id":"W4247717918","doi":"10.1038/s41434-018-0054-3","title":"Correction: Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials","year":2019,"lang":"en","type":"erratum","venue":"Gene Therapy","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"License; Publication; Epistasis; Biology; Value (mathematics); Computational biology; Bioinformatics; Genetics; Computer science; Gene; Machine learning; Political science","score_opus":0.05248100020684298,"score_gpt":0.3157488446584001,"score_spread":0.2632678444515571,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4247717918","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00040888492,0.000808564,0.0025994943,0.061608415,0.9281123,0.000031876454,0.0013089059,0.00087458594,0.0042467765],"genre_scores_gemma":[0.039255463,0.008668745,0.024884943,0.12830366,0.36798382,0.00035060477,0.0053145722,0.0060197045,0.41921845],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99627507,0.0005156497,0.00057422713,0.00061406964,0.0017323554,0.0002887274],"domain_scores_gemma":[0.9746488,0.007959286,0.001308403,0.0016639855,0.012968066,0.0014514709],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0039544813,0.0018838968,0.0013130134,0.002709549,0.0026306554,0.002895733,0.00326475,0.0061532543,0.057005808],"category_scores_gemma":[0.05372728,0.0009255507,0.0012217037,0.0015120598,0.0024976318,0.001887952,0.0017707312,0.01255444,0.025625264],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061588406,0.000008562099,0.000107519394,0.00012523732,0.000020565987,0.0007267807,0.00003481969,0.00006133736,0.00024067968,0.0016361036,0.9880086,0.008968183],"study_design_scores_gemma":[0.000061575374,0.000025586269,0.00076578686,0.00030226368,0.0000636378,0.0022772085,0.00007013683,0.00041814448,0.0013322891,0.003685832,0.99093866,0.000058805752],"about_ca_topic_score_codex":0.009952225,"about_ca_topic_score_gemma":0.014511911,"teacher_disagreement_score":0.057005808,"about_ca_system_score_codex":0.0030986995,"about_ca_system_score_gemma":0.0034162449,"threshold_uncertainty_score":0.19070345},"labels":[],"label_agreement":null},{"id":"W4256206805","doi":"10.1038/sj.gt.3302905","title":"Erratum: Gene delivery to human sweat glands: a model for cystic fibrosis gene therapy","year":2007,"lang":"en","type":"erratum","venue":"Gene Therapy","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Institutes of Health","keywords":"Genetic enhancement; Cystic fibrosis; Gene; Gene delivery; Medicine; Biology; Internal medicine; Genetics","score_opus":0.04714007090828329,"score_gpt":0.34473739437917916,"score_spread":0.29759732347089585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4256206805","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027505096,0.0043052076,0.0006917517,0.029789649,0.96224374,0.000029239496,0.00017367242,0.000097212214,0.0023944941],"genre_scores_gemma":[0.012679782,0.059649225,0.011709032,0.14835036,0.46069568,0.00027963007,0.0021794245,0.00094774575,0.30350912],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99803334,0.0002660125,0.00041511375,0.00017748108,0.00093589886,0.0001721466],"domain_scores_gemma":[0.9927993,0.0025056377,0.00056143163,0.0003858737,0.0031629405,0.0005848388],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023687952,0.0031472193,0.00227999,0.00368371,0.0025002477,0.0022202716,0.0031065575,0.009018165,0.012786822],"category_scores_gemma":[0.012054535,0.0014029646,0.0020700484,0.0019808214,0.0022093146,0.0023369452,0.0011972773,0.009657198,0.013852538],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011875034,0.000037059723,0.00007224834,0.00035582998,0.000024897594,0.0010730014,0.000025968457,0.00010888105,0.0006699155,0.00092737086,0.9844976,0.012088433],"study_design_scores_gemma":[0.00006672219,0.00011308187,0.0005744979,0.0002976817,0.00012135316,0.0019794449,0.00008281551,0.00031281143,0.0029646743,0.0008714019,0.9925569,0.000058548507],"about_ca_topic_score_codex":0.005132881,"about_ca_topic_score_gemma":0.0068456256,"teacher_disagreement_score":0.012786822,"about_ca_system_score_codex":0.002814201,"about_ca_system_score_gemma":0.0029453505,"threshold_uncertainty_score":0.042776227},"labels":[],"label_agreement":null},{"id":"W4281550232","doi":"10.1038/s41434-022-00349-y","title":"Curing SMA: Are we there yet?","year":2022,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Muscular Dystrophy Canada; Government of Canada; Muscular Dystrophy Association","keywords":"SMA*; SMN1; Spinal muscular atrophy; Motor neuron; Disease; Biology; Natural history; Neuromuscular disease; Neuroscience; Bioinformatics; Intensive care medicine; Medicine; Internal medicine; Spinal cord; Computer science","score_opus":0.2324733042154415,"score_gpt":0.4187599251534376,"score_spread":0.18628662093799608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281550232","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000028138078,0.998565,0.00007395101,0.0005519679,0.00036840118,0.0000022149818,0.000009242011,0.0000060655807,0.0003950048],"genre_scores_gemma":[0.0002722984,0.99811316,0.00017844608,0.00069758506,0.00032981593,0.000005160333,0.000018362718,0.0000020148518,0.00038323188],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997249,0.00006618069,0.00003870947,0.00004577877,0.00008868564,0.000035754823],"domain_scores_gemma":[0.99934715,0.00041300702,0.000060014336,0.000018018849,0.000108800916,0.00005305877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012526667,0.0011518839,0.002612911,0.0014162497,0.00034153412,0.0017803395,0.0013611484,0.0023324103,0.0049490537],"category_scores_gemma":[0.0016734382,0.0003128221,0.0006933371,0.0013436549,0.00079019874,0.002255746,0.0007996034,0.0039018404,0.0027197783],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016268386,0.000079930796,0.000113989074,0.01616272,0.00012385202,0.00017702095,0.00004616815,0.00032383937,0.0011092256,0.00396898,0.060893733,0.9168379],"study_design_scores_gemma":[0.0000818324,0.000119647535,0.00032933982,0.0077743446,0.00024269572,0.0007229526,0.00006543196,0.00008974913,0.00024054402,0.0028894339,0.9874206,0.000023345998],"about_ca_topic_score_codex":0.00091188395,"about_ca_topic_score_gemma":0.0026963225,"teacher_disagreement_score":0.0049490537,"about_ca_system_score_codex":0.0006569007,"about_ca_system_score_gemma":0.0011405163,"threshold_uncertainty_score":0.016556263},"labels":[],"label_agreement":null},{"id":"W4288096287","doi":"10.1038/s41434-022-00359-w","title":"rAAV-mediated over-expression of acid ceramidase prevents retinopathy in a mouse model of Farber lipogranulomatosis","year":2022,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Retinopathy; Retinal; Ceramide; Fundus (uterus); Biology; Ectopic expression; Electroretinography; Phenotype; Retina; Pathology; Medicine; Endocrinology; Gene; Ophthalmology; Biochemistry; Diabetes mellitus; Neuroscience; Apoptosis","score_opus":0.01830320587326075,"score_gpt":0.26874071685252104,"score_spread":0.2504375109792603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288096287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99150944,0.0018212879,0.0032813412,0.00025612154,0.0001010716,0.000056429446,0.00031813406,0.00043961612,0.0022165822],"genre_scores_gemma":[0.9880728,0.0009721443,0.0031063997,0.00007420633,0.00002226846,0.000057653993,0.00024600336,0.00006752441,0.0073810313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995888,0.00008278586,0.00003813483,0.0000942194,0.00008768991,0.0001083364],"domain_scores_gemma":[0.9996309,0.000053379572,0.00015474731,0.000042111616,0.00002181957,0.000096955926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000481683,0.0009518312,0.00054997904,0.0012022885,0.00037620924,0.00052517996,0.00046897714,0.0010985966,0.002268618],"category_scores_gemma":[0.00019632356,0.00038555072,0.000448171,0.0002972959,0.0006996058,0.00057411136,0.0002465554,0.0014001529,0.00058112596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032566552,0.0001362819,0.00008066601,0.000036543228,0.0000071181694,0.00021954853,0.00002968335,0.00009027661,0.99799037,0.00025021777,0.00004881232,0.0007847761],"study_design_scores_gemma":[0.00007973862,0.0007699088,0.0018881791,0.000016478141,0.000036762358,0.00072240137,0.00007400374,0.0010997693,0.9938247,0.00010642574,0.0013682921,0.000013286462],"about_ca_topic_score_codex":0.0010319803,"about_ca_topic_score_gemma":0.0012184597,"teacher_disagreement_score":0.002268618,"about_ca_system_score_codex":0.00045119366,"about_ca_system_score_gemma":0.00034494,"threshold_uncertainty_score":0.0075892806},"labels":[],"label_agreement":null},{"id":"W4289918643","doi":"10.1038/s41434-022-00358-x","title":"Preclinical assessment of antigen-specific chimeric antigen receptor regulatory T cells for use in solid organ transplantation","year":2022,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Sangamo Therapeutics","keywords":"Immunosuppression; Immunology; Transplantation; Antigen; Human leukocyte antigen; Biology; Immune system; Tacrolimus; Peripheral blood mononuclear cell; Proinflammatory cytokine; Humanized mouse; Medicine; In vitro; Inflammation; Internal medicine","score_opus":0.08355808030394156,"score_gpt":0.3849365013374286,"score_spread":0.30137842103348705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289918643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9798693,0.0015980242,0.013629433,0.00010198009,0.00012245128,0.0013886716,0.000534601,0.0002105519,0.002544979],"genre_scores_gemma":[0.988331,0.0013644799,0.0064172964,0.00008307846,0.00005306464,0.00064648624,0.0011925838,0.000035866862,0.001876085],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99953544,0.00014115467,0.000041046318,0.000046531713,0.00012082814,0.0001150976],"domain_scores_gemma":[0.9996946,0.00007085312,0.000062229745,0.000043234802,0.00006424133,0.00006485425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011906935,0.0007302329,0.0004048157,0.00030508934,0.00017663545,0.0005972927,0.00051509845,0.0006572498,0.0013966677],"category_scores_gemma":[0.00047200936,0.00014521932,0.000398085,0.00016965598,0.00025011378,0.00038333144,0.0001638528,0.0012845747,0.00041102344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091577426,0.0029916423,0.00034007264,0.000109445056,0.000020669899,0.000071508955,0.000057375277,0.0012573082,0.9871127,0.00021468723,0.0001389676,0.0067697833],"study_design_scores_gemma":[0.00034217554,0.06980128,0.0012158864,0.000019066916,0.000099674435,0.0002222408,0.000041380994,0.0023840421,0.9229024,0.00012684207,0.0028339566,0.000010970646],"about_ca_topic_score_codex":0.00029043845,"about_ca_topic_score_gemma":0.00034519806,"teacher_disagreement_score":0.0013966677,"about_ca_system_score_codex":0.00023679166,"about_ca_system_score_gemma":0.00047683853,"threshold_uncertainty_score":0.006297052},"labels":[],"label_agreement":null},{"id":"W4294251783","doi":"10.1038/s41434-022-00361-2","title":"Adeno-associated virus mediated expression of monoclonal antibody MR191 protects mice against Marburg virus and provides long-term expression in sheep","year":2022,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada; University of Guelph","funders":"","keywords":"Monoclonal antibody; Biology; Virology; Virus; Antibody; Capsid; Immune system; Immunology; Recombinant DNA; Gene","score_opus":0.02692614232518118,"score_gpt":0.3192706715774072,"score_spread":0.292344529252226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294251783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901571,0.0016829987,0.0054257936,0.00018495462,0.00008053559,0.000042938304,0.00047469095,0.00021858337,0.0017324702],"genre_scores_gemma":[0.986035,0.0009814185,0.0027522915,0.00004490711,0.000030741732,0.00004211172,0.00089230423,0.00008492065,0.0091362195],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977463,0.00003199679,0.000018291636,0.00005629274,0.00004419269,0.00007463895],"domain_scores_gemma":[0.99971503,0.00005431655,0.00011083229,0.000031865406,0.000017905651,0.00006999931],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002501064,0.0004997708,0.00029111627,0.0005880693,0.00018173025,0.00045435727,0.0004476616,0.00055298547,0.0017662176],"category_scores_gemma":[0.00013687389,0.00024792145,0.00034637924,0.00014081298,0.00039798935,0.00039956605,0.00021721197,0.0012670936,0.00077473104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069963404,0.000026446183,0.00005316609,0.000009441232,0.0000022670129,0.00002114049,0.000010992579,0.000019773888,0.9992555,0.0001442599,0.00001792352,0.00036921373],"study_design_scores_gemma":[0.000021818478,0.00038117878,0.0009751367,0.0000058481696,0.000017538463,0.000116501076,0.000022898934,0.0003690606,0.9964886,0.00004700524,0.0015511228,0.0000033125043],"about_ca_topic_score_codex":0.00049790234,"about_ca_topic_score_gemma":0.00071277504,"teacher_disagreement_score":0.0017662176,"about_ca_system_score_codex":0.00029199853,"about_ca_system_score_gemma":0.00018930524,"threshold_uncertainty_score":0.005908549},"labels":[],"label_agreement":null},{"id":"W4319036852","doi":"10.1038/s41434-023-00385-2","title":"Antibody-based protection against respiratory syncytial virus in mice and their offspring through vectored immunoprophylaxis","year":2023,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Respiratory viral infections research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Palivizumab; Monoclonal antibody; Virology; Passive immunity; Biology; Immunology; Virus; Antibody; Respiratory tract; Immunity; Respiratory system; Medicine; Immune system","score_opus":0.07143656665347546,"score_gpt":0.35532754869209116,"score_spread":0.2838909820386157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319036852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98930573,0.001706963,0.0057628746,0.00034913336,0.00013473943,0.000101282225,0.00036935383,0.0002231502,0.0020469232],"genre_scores_gemma":[0.98719984,0.0015496123,0.0039907326,0.00014794174,0.000042319218,0.00011637979,0.00041145147,0.000047850986,0.006493918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99966145,0.000071096336,0.000021690108,0.000092734,0.000061694685,0.00009130622],"domain_scores_gemma":[0.9997967,0.000034689394,0.00007146873,0.000028779477,0.0000205119,0.000047846122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038594325,0.0006185648,0.00040189593,0.0006595427,0.00021608762,0.000506905,0.000646719,0.00087106513,0.0020250124],"category_scores_gemma":[0.00020399861,0.00019504527,0.0003289262,0.00017458313,0.0005715943,0.00041972828,0.00026815105,0.0013679224,0.0003607697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080196414,0.0005138357,0.00032079022,0.000048470338,0.000018776049,0.000088308385,0.000060440303,0.00012945286,0.9907698,0.00075655145,0.00014586025,0.006345741],"study_design_scores_gemma":[0.00027407284,0.0063693565,0.0050796536,0.00003142115,0.000106092724,0.00070568436,0.00010241101,0.0017056558,0.9800454,0.00036408947,0.0051938393,0.000022325346],"about_ca_topic_score_codex":0.00050782337,"about_ca_topic_score_gemma":0.0005217932,"teacher_disagreement_score":0.0020250124,"about_ca_system_score_codex":0.00023403516,"about_ca_system_score_gemma":0.00027533845,"threshold_uncertainty_score":0.0067743063},"labels":[],"label_agreement":null},{"id":"W4320482686","doi":"10.1038/s41434-023-00389-y","title":"Sonoselective delivery using ultrasound and microbubbles combined with intravenous rAAV9 CLDN5-GFP does not increase endothelial gene expression","year":2023,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Children's Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"Carlsbergfondet; Government of Canada; National Institute of Biomedical Imaging and Bioengineering; Weston Brain Institute","keywords":"Microbubbles; Gene delivery; Transgene; Genetic enhancement; Biology; Transduction (biophysics); Molecular biology; Gene expression; Blood–brain barrier; Endothelium; Endothelial stem cell; Green fluorescent protein; Cell biology; Pathology; Gene; Medicine; Central nervous system; Ultrasound; Biophysics; In vitro; Neuroscience; Endocrinology; Biochemistry","score_opus":0.011149582786458084,"score_gpt":0.20632821155507758,"score_spread":0.1951786287686195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320482686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9836962,0.0019062009,0.009493131,0.0002836812,0.00017277116,0.000070971444,0.00031903258,0.00030730755,0.0037506947],"genre_scores_gemma":[0.9826156,0.001004834,0.007190058,0.00012923124,0.00004268944,0.000057634676,0.0005035145,0.00015083338,0.008305747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951196,0.000086999404,0.00003492608,0.00011493453,0.00009923834,0.00015189846],"domain_scores_gemma":[0.9995765,0.00014961649,0.00009165204,0.00005165866,0.00003214734,0.00009839666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004428299,0.00046344992,0.00062335504,0.000267579,0.00020404198,0.00064028584,0.00040830555,0.000460598,0.00228578],"category_scores_gemma":[0.0003223649,0.00031240337,0.00031083595,0.00018281807,0.00048659267,0.0005403519,0.00020761469,0.0012119688,0.00056117726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027701925,0.00007990215,0.00008672503,0.000029913943,0.00000954723,0.000031560874,0.000023617546,0.000094812254,0.9974474,0.00020817411,0.00009842615,0.0016129522],"study_design_scores_gemma":[0.000015376001,0.00025317798,0.00043933114,0.0000026976468,0.000016368947,0.00005254508,0.00001333394,0.00074426056,0.9974617,0.000016089125,0.0009815344,0.0000034986535],"about_ca_topic_score_codex":0.003813253,"about_ca_topic_score_gemma":0.0044774255,"teacher_disagreement_score":0.003813253,"about_ca_system_score_codex":0.00056825596,"about_ca_system_score_gemma":0.0006110668,"threshold_uncertainty_score":0.00764668},"labels":[],"label_agreement":null},{"id":"W4320710600","doi":"10.1038/s41434-023-00387-0","title":"Removal of the GAA repeat in the heart of a Friedreich’s ataxia mouse model using CjCas9","year":2023,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Government of Canada; Ataxia Canada; National Ataxia Foundation","keywords":"Ataxia; Biology; Virology; Neuroscience","score_opus":0.10967425357025201,"score_gpt":0.3191227660801092,"score_spread":0.2094485125098572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320710600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98504597,0.0011643844,0.007432152,0.00077374186,0.00048640804,0.00012893237,0.0009800883,0.00046545602,0.0035229684],"genre_scores_gemma":[0.9822296,0.0009298679,0.005495987,0.00022712801,0.000061010458,0.0001070626,0.0005996454,0.000118620694,0.010231074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978036,0.000023785708,0.000027247832,0.00006825155,0.000055548902,0.000044805434],"domain_scores_gemma":[0.9997402,0.000030835046,0.00008388481,0.000026164427,0.000016697486,0.00010223946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002682641,0.00066120195,0.0003710917,0.0008966659,0.00048595143,0.00042350692,0.0006381448,0.001166983,0.0025417807],"category_scores_gemma":[0.00017997171,0.00032512355,0.00056970207,0.0002412825,0.00080475013,0.00040150093,0.00024071171,0.001536327,0.00063990976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027675004,0.00010555812,0.00006901208,0.000033463144,0.000013985294,0.00040727443,0.000017936796,0.000117630196,0.99703217,0.00056321674,0.0001921243,0.0011709217],"study_design_scores_gemma":[0.0002672654,0.0008290142,0.0024030523,0.00002190975,0.000093937335,0.001972191,0.000058172252,0.0020610043,0.98682564,0.00029977525,0.0051489524,0.000019054629],"about_ca_topic_score_codex":0.0012415586,"about_ca_topic_score_gemma":0.0016152199,"teacher_disagreement_score":0.0025417807,"about_ca_system_score_codex":0.0004243222,"about_ca_system_score_gemma":0.0003976575,"threshold_uncertainty_score":0.008503079},"labels":[],"label_agreement":null},{"id":"W4366352907","doi":"10.1038/s41434-023-00400-6","title":"rAAV-PHP.B escapes the mouse eye and causes lethality whereas rAAV9 can transduce aniridic corneal limbal stem cells without lethality","year":2023,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Corneal Surgery and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; British Columbia Knowledge Development Fund; Foundation Fighting Blindness; Government of Canada; Canada Foundation for Innovation; BC Children's Hospital","keywords":"Aniridia; PAX6; Gene delivery; Biology; Genetic enhancement; Transduction (biophysics); Adeno-associated virus; Virology; Ophthalmology; Medicine; Genetics; Gene; Recombinant DNA; Vector (molecular biology)","score_opus":0.048377547322265735,"score_gpt":0.2921559127128007,"score_spread":0.243778365390535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366352907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9743329,0.0024720894,0.016998054,0.00017416601,0.000040359424,0.00009410266,0.00092719885,0.00046702608,0.0044941395],"genre_scores_gemma":[0.9788063,0.001645449,0.010863325,0.00012672662,0.000011804522,0.0001103968,0.001056321,0.0001681295,0.0072116363],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995572,0.0000708717,0.000049850158,0.00012958268,0.00012568918,0.000066857436],"domain_scores_gemma":[0.9995454,0.000095061434,0.00016883056,0.000080652135,0.00003202731,0.00007792041],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028875424,0.00068260304,0.00028252442,0.00053893845,0.00019803422,0.0004042741,0.000385437,0.00062988914,0.0015850737],"category_scores_gemma":[0.0001741012,0.00024772203,0.00036847653,0.00017174882,0.0004862707,0.000297193,0.00025604622,0.0011952547,0.0006843273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002385811,0.000016051543,0.00012924193,0.000028207516,0.0000044839862,0.000055682718,0.0000117060545,0.000029746203,0.9988092,0.000111446556,0.000018550738,0.0007617479],"study_design_scores_gemma":[0.000011332591,0.00043018587,0.0036218099,0.000012014467,0.00001630053,0.0008839595,0.000024547171,0.00048535084,0.9924509,0.000077492004,0.001980219,0.000005786846],"about_ca_topic_score_codex":0.00071310723,"about_ca_topic_score_gemma":0.0008886814,"teacher_disagreement_score":0.0015850737,"about_ca_system_score_codex":0.00021502301,"about_ca_system_score_gemma":0.0002477579,"threshold_uncertainty_score":0.0053025484},"labels":[],"label_agreement":null},{"id":"W4385902677","doi":"10.1038/s41434-023-00416-y","title":"Safety and biodistribution of XC001 (encoberminogene rezmadenovec) gene therapy in rats: a potential therapy for cardiovascular diseases","year":2023,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Genetic enhancement; Biodistribution; Spleen; Medicine; Gene delivery; Pathology; Internal medicine; Immunology; Pharmacology; Biology; Gene; In vivo","score_opus":0.019483381478716377,"score_gpt":0.28389903028785357,"score_spread":0.2644156488091372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385902677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928763,0.00076466246,0.0045503266,0.0000826006,0.000027185431,0.000046755587,0.0003160787,0.00010612865,0.0012300431],"genre_scores_gemma":[0.989952,0.0008609652,0.0024415366,0.00005149913,0.000019908095,0.00006491953,0.00046173757,0.000051376788,0.006095989],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99970883,0.00005395313,0.000014583865,0.00007689368,0.00007431081,0.00007136478],"domain_scores_gemma":[0.99963486,0.000064362765,0.00013809635,0.000055958815,0.00005829427,0.000048393926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044091928,0.00045772197,0.00026731225,0.0005215157,0.0002249618,0.0004164788,0.00034077239,0.00060004037,0.0012701119],"category_scores_gemma":[0.0003352047,0.00019173764,0.00025884958,0.0002365703,0.0005471235,0.0005246928,0.00011984494,0.00059974135,0.00038067577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035233626,0.00036341522,0.0010884557,0.000049408252,0.000016919681,0.00009561822,0.0000705216,0.0003409675,0.98794997,0.00034875935,0.000086102824,0.006066447],"study_design_scores_gemma":[0.00004987804,0.004240559,0.003049376,0.000007456209,0.000051765383,0.00015830465,0.000054026248,0.0011511864,0.99008346,0.000077330675,0.0010617186,0.000014813658],"about_ca_topic_score_codex":0.0019425554,"about_ca_topic_score_gemma":0.0012496129,"teacher_disagreement_score":0.0019425554,"about_ca_system_score_codex":0.00046294898,"about_ca_system_score_gemma":0.00073614996,"threshold_uncertainty_score":0.0042489767},"labels":[],"label_agreement":null},{"id":"W4395693065","doi":"10.1038/s41434-024-00453-1","title":"AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumonia","year":2024,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Government of Canada","keywords":"Pseudomonas aeruginosa; Monoclonal antibody; Biology; Microbiology; Virology; Pathogen; Pneumonia; Cystic fibrosis; Antibiotics; Antibody; Immunology; Medicine; Bacteria","score_opus":0.03192260880352587,"score_gpt":0.2685425019164961,"score_spread":0.23661989311297021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395693065","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98489285,0.001766393,0.008698568,0.00046779297,0.00030155023,0.00011316602,0.0006948253,0.0007080327,0.002356869],"genre_scores_gemma":[0.979832,0.0013914077,0.0056997957,0.00021264292,0.0001001291,0.00013288819,0.00082123047,0.00012152479,0.01168843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994295,0.000065304586,0.000054818658,0.00012469977,0.00014138165,0.00018421559],"domain_scores_gemma":[0.9995419,0.000060720624,0.00016752748,0.00003639971,0.000036664493,0.0001567484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039059363,0.0009652564,0.00062074704,0.0010060832,0.0002823055,0.00062512857,0.0005472821,0.0011498694,0.0019260588],"category_scores_gemma":[0.00019243601,0.0004532686,0.00038821207,0.00027649512,0.0006225574,0.0005158035,0.00026302482,0.0020081287,0.0005778573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023910672,0.0000962896,0.000090786976,0.0000262428,0.000007768195,0.000034320088,0.000011910295,0.0000807165,0.99823797,0.00020732194,0.00006964484,0.0008979737],"study_design_scores_gemma":[0.00006711066,0.00083607953,0.0014400671,0.000014956173,0.000037716065,0.00017842054,0.00003102066,0.0012397276,0.99420565,0.000119178425,0.0018204622,0.000009797149],"about_ca_topic_score_codex":0.0010957667,"about_ca_topic_score_gemma":0.00161696,"teacher_disagreement_score":0.0019260588,"about_ca_system_score_codex":0.0005648088,"about_ca_system_score_gemma":0.0005026423,"threshold_uncertainty_score":0.0064433217},"labels":[],"label_agreement":null},{"id":"W4408854527","doi":"10.1038/s41434-025-00524-x","title":"Optimization of adeno-associated viral (AAV) gene therapies vectors for balancing efficacy, longevity and safety for clinical application","year":2025,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; BC Children's Hospital; McGill University; University of British Columbia","funders":"National Research Council Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC; Government of Canada","keywords":"Adeno-associated virus; Genetic enhancement; Longevity; Biology; Virology; Gene transfer; Gene delivery; Vector (molecular biology); Gene; Genetics; Recombinant DNA","score_opus":0.02440312465991572,"score_gpt":0.3565630768798135,"score_spread":0.33215995221989775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408854527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8804265,0.005192401,0.10936711,0.0002646608,0.0001047851,0.0004983773,0.00044901553,0.0003544545,0.003342745],"genre_scores_gemma":[0.914468,0.0028735162,0.0796086,0.00007024559,0.00002628027,0.00029908738,0.00044889958,0.00015349576,0.0020519013],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992046,0.00015675425,0.00009420645,0.0001166287,0.00034353582,0.00008436924],"domain_scores_gemma":[0.99966776,0.00008465463,0.00012921974,0.000021037105,0.00006241875,0.00003494862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011205343,0.00078193366,0.00053095014,0.00059049175,0.00028559795,0.0011379643,0.00035318412,0.00037442657,0.0007646391],"category_scores_gemma":[0.0008491202,0.00027955,0.00033451576,0.00050916476,0.00042491782,0.00057466456,0.00033070968,0.00064677384,0.00033843453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012414015,0.00009136009,0.0002801541,0.000071648385,0.000013791259,0.000022009572,0.00002741234,0.0021322079,0.9891053,0.00097440544,0.000071661976,0.0070859427],"study_design_scores_gemma":[0.000032661053,0.00068165356,0.0011574752,0.000018144321,0.00006132773,0.00011828075,0.000034554436,0.007854649,0.9853338,0.0003886055,0.004294093,0.000024740059],"about_ca_topic_score_codex":0.0007077853,"about_ca_topic_score_gemma":0.0015998153,"teacher_disagreement_score":0.0011379643,"about_ca_system_score_codex":0.00090875116,"about_ca_system_score_gemma":0.0008877326,"threshold_uncertainty_score":0.006593466},"labels":[],"label_agreement":null},{"id":"W4411586250","doi":"10.1038/s41434-025-00547-4","title":"Preclinical evaluation of lentiviral gene therapy for adenosine deaminase 2 deficiency (DADA2): engraftment efficiency and biodistribution in humanised NBSGW mice","year":2025,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Great Ormond Street Hospital Charity; Rosetrees Trust; National Institute for Health and Care Research; Action Medical Research; University College London; LifeArc; Wellcome Trust","keywords":"Adenosine deaminase deficiency; Genetic enhancement; Haematopoiesis; Severe combined immunodeficiency; Biology; Stem cell; Immunology; Transplantation; Cancer research; Adenosine deaminase; Viral vector; Chronic granulomatous disease; In vivo; Medicine; Adenosine; Cell biology; Gene; Internal medicine; Recombinant DNA","score_opus":0.05058542497343813,"score_gpt":0.3781850293161237,"score_spread":0.32759960434268554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411586250","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885796,0.0018650419,0.00703636,0.000087869405,0.000040575935,0.00035127337,0.00051351084,0.00016644607,0.0013593078],"genre_scores_gemma":[0.98876965,0.0014978305,0.006063906,0.000050534065,0.000015399897,0.00033458765,0.0007916706,0.000051418247,0.0024249286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99969625,0.000081236125,0.000024482304,0.00006177873,0.000081041435,0.000055251123],"domain_scores_gemma":[0.99982685,0.000037473623,0.000045463723,0.000025154233,0.000023149554,0.000042023057],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00088291505,0.0006467094,0.00043312437,0.00035947765,0.00016829565,0.00043829283,0.00047985607,0.00063690863,0.00094119494],"category_scores_gemma":[0.00023663843,0.0001886929,0.0002785356,0.00022345813,0.0004642588,0.00034678946,0.00016898855,0.00096119684,0.0003460315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052788877,0.00059151865,0.00015150901,0.000060640225,0.000012007173,0.000051352472,0.0000475424,0.00041686604,0.99530303,0.000121034056,0.00007775436,0.0026388802],"study_design_scores_gemma":[0.00012741193,0.010768083,0.001179063,0.000009264444,0.000044799308,0.00021004013,0.000020278969,0.0015579292,0.9841474,0.00005156452,0.0018755125,0.000008637421],"about_ca_topic_score_codex":0.0010327976,"about_ca_topic_score_gemma":0.00072993967,"teacher_disagreement_score":0.0010327976,"about_ca_system_score_codex":0.00039060257,"about_ca_system_score_gemma":0.00029641174,"threshold_uncertainty_score":0.0046693087},"labels":[],"label_agreement":null},{"id":"W4417198906","doi":"10.1038/s41434-025-00584-z","title":"Lipid nanoparticle mediated base editing of the Q344X rhodopsin mutation associated with retinitis pigmentosa","year":2025,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Rhodopsin; Transfection; Plasmid; Mutation; Genome editing; RNA editing; genomic DNA; Cas9; Reporter gene","score_opus":0.008054652548033083,"score_gpt":0.22452477056590148,"score_spread":0.2164701180178684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417198906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923241,0.00034206535,0.004794995,0.00024997842,0.000076856915,0.000043587257,0.00007092888,0.00009154323,0.0020059322],"genre_scores_gemma":[0.99626833,0.00014183532,0.0018921108,0.000041461382,0.000006254511,0.0000064588066,0.000036919373,0.000020423338,0.0015862344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999082,0.00001974735,0.000008915899,0.000019068262,0.000025352667,0.000018649083],"domain_scores_gemma":[0.99992895,0.000027366266,0.00001747072,0.000007668968,0.0000055301603,0.000012996007],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001120927,0.00019345945,0.00018561754,0.00015516765,0.0001798866,0.00017407296,0.0002044999,0.0006503339,0.0012140978],"category_scores_gemma":[0.0001839427,0.00008815257,0.00023313786,0.0000669676,0.00022133028,0.00010836075,0.00020378087,0.00036061893,0.00025004486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001423095,0.000046309517,0.0001444136,0.000024387953,0.000008341729,0.0019539262,0.000028101673,0.00027264716,0.993421,0.00027175623,0.000077868746,0.0036089562],"study_design_scores_gemma":[0.000044272907,0.0004208576,0.0014070862,0.00000799077,0.000036715257,0.004850904,0.00003129107,0.00324357,0.98640084,0.00021917693,0.0033197356,0.000017552717],"about_ca_topic_score_codex":0.00069782924,"about_ca_topic_score_gemma":0.0006462664,"teacher_disagreement_score":0.0012140978,"about_ca_system_score_codex":0.00019856136,"about_ca_system_score_gemma":0.00011717739,"threshold_uncertainty_score":0.00406152},"labels":[],"label_agreement":null},{"id":"W8542398","doi":"","title":"Teachers' Perceptions of First Nations, Metis and Inuit Students in Alberta Public School Classrooms","year":2008,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Indigenous Health, Education, and Rights","field":"Social Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Metis; Perception; Geography; Pedagogy; Political science; Mathematics education; Psychology; Computer science","score_opus":0.022090117340919507,"score_gpt":0.3174728483322941,"score_spread":0.2953827309913746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W8542398","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966518,0.00012765192,0.000050641833,0.00024052277,0.0000067846154,0.000018231389,0.000013302103,0.000004499616,0.0028866103],"genre_scores_gemma":[0.99723536,0.00019765188,0.000086848275,0.00008942834,0.000002266879,0.000020664187,0.00001726788,0.000004069625,0.0023464393],"study_design_codex":"qualitative","study_design_gemma":"qualitative","domain_scores_codex":[0.9978219,0.000634526,0.000061953906,0.00015190404,0.00052328507,0.00080636825],"domain_scores_gemma":[0.99780923,0.0005430597,0.00025788456,0.0000444147,0.000433871,0.000911497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022611506,0.0005485642,0.00054637855,0.0014788356,0.012924523,0.0046493053,0.0017350486,0.00086057134,0.0023278566],"category_scores_gemma":[0.0031552613,0.00051567645,0.0001954284,0.0014587139,0.005628835,0.00085923297,0.0031646339,0.0017914837,0.00015718381],"study_design_candidate":"qualitative","study_design_consensus":"qualitative","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022742357,0.00006453701,0.027808353,0.000035951958,0.0000029621272,0.00049094757,0.9666559,0.000024398592,0.0008308973,0.00044507656,0.00023878344,0.0033794602],"study_design_scores_gemma":[0.0000014873178,0.000032648022,0.015441682,0.000035752048,0.000003241152,0.000054655808,0.9822364,0.000030558247,0.00010547307,0.000028627888,0.002022426,0.0000070783412],"about_ca_topic_score_codex":0.7758799,"about_ca_topic_score_gemma":0.92665493,"teacher_disagreement_score":0.22412008,"about_ca_system_score_codex":0.02098208,"about_ca_system_score_gemma":0.020179635,"threshold_uncertainty_score":0.45087993},"labels":[],"label_agreement":null}]}